| Title |
Indication |
Intervention |
Actions |
PatientSelection |
Sponsor |
Collaborator |
Country |
StartDate |
EndDate |
Identifiers |
Phase |
Recruitment Status |
Sites |
Trial Duration |
Enrollment Count |
Contacts |
LastChanged |
| Coronavirus Disease 2019 (COVID-19) Study of Hospitalized Patients in Hong Kong |
Coronavirus disease 19 infection, Viral pneumonia |
laboratory monitoring alone, nasopharyngeal aspiration alone, sputum collection alone, swab flocking alone, tracheal aspiration alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Chinese University of Hong Kong |
|
Hong Kong |
2020-02-24 |
2021-06-17 |
COVID-19 STUDY 2020.076, NCT04325919 |
Phase Not Applicable |
Recruiting |
0 |
15 Months |
170 |
Paul CHAN, Paul KS Chan |
2020-03-31 |
| Psychological distress of the COVID-19 pandemic: A comparison between cancer patients and healthy controls |
Anxiety disorder, Coronavirus disease 19 infection, Depression |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Klinik fur Psychosomatische Medizin und Psychotherapie, Univeristat Duisburg-Essen |
|
Germany |
2020-03-16 |
|
19-8834-BO, DRKS00021164 |
Phase Not Applicable |
Recruiting |
0 |
|
220 |
Venja Musche |
2020-03-31 |
| COVIDx: Evaluation of Novel Diagnostic Tests for 2019-nCOV |
Coronavirus disease 19 infection |
CT scan alone, SAMBA II device alone, chest X-ray alone, polymerase chain reaction alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cambridge University Hospitals NHS Foundation Trust |
|
UK |
2020-04-08 |
2021-10-07 |
COVIDX, COVIDx, NCT04326387 |
Phase Not Applicable |
Not yet recruiting |
0 |
18 Months |
200 |
Anne-Laure Vallier, PhD., Ravindra Prof. Gupta, BMBCh, Richard D. Skells, BSc. |
2020-03-31 |
| Effectiveness and Safety of Respiratory Training in the Prevention and Severity of COVID-19 |
Coronavirus disease 19 infection |
Power-breath device alone, Winner-flow device alone, expiratory training alone, inspiratory training alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universidad Complutense de Madrid |
|
Spain |
2020-04-26 |
2020-10-12 |
COVID_ISCIII 20/265-E_BS, NCT04326114 |
Phase Not Applicable |
Not yet recruiting |
0 |
5 Months |
240 |
César Calvo Lobo, César Calvo Lobo, PhD |
2020-03-31 |
| GRECCO-19: The GReek Study in the Effects of Colchicine in Covid-19 |
Coronavirus disease 19 infection, SARS coronavirus infection |
Colchicine alone, Standard treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National and Kapodistrian University of Athens |
|
|
2020-04-01 |
2020-09-30 |
906295542, GRECCO-19, NCT04326790 |
Phase 4 Clinical |
Not yet recruiting |
0 |
6 Months |
180 |
Spyridon Deftereos |
2020-03-31 |
| CoV-Ak-Test: Development of a test to measure the immune response in patients with Covid-19 |
Coronavirus disease 19 infection |
SARS-CoV-2 antibody ELISA alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Institut für Virologie, Universitätsklinikum Leipzig |
|
Germany |
2020-03-30 |
|
124/20-ek, CoV-Ak-Test, DRKS00021166 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
15 |
Christian Jassoy |
2020-03-31 |
| A Phase I Study to Assess the Effect of Gimsilumab in The Treatment of COVID-19 Associated With Acute Respiratory Distress Syndrome (ARDS) Patients |
Coronavirus disease 19 infection, Respiratory distress syndrome |
gimsilumab alone |
GM-CSF ligand inhibitor |
|
Altasciences Company Inc, Roivant Sciences Ltd |
|
|
|
2020-03-27 |
|
Phase 1 Clinical |
Completed |
0 |
|
|
|
2020-03-31 |
| Clinical Trial of renin-angiotensin-aldosterone system inhibitors with halting their administration and the effect on clinical outcomes of patients with corona virus disease-2019 (COVID-19) referring to Sina Hospital in 2020 |
Coronavirus disease 19 infection |
beta-blocker therapy alone, calcium channel blocker therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tehran University of Medical Sciences |
|
Iran |
2020-04-05 |
|
IR.TUMS.VCR.REC.1399.028, IRCT20151113025025N3 |
Phase 4 Clinical |
Not yet recruiting |
1 |
|
60 |
Maryam Bahreini, Mohammad Ali Sahraian |
2020-03-31 |
| Active Monitoring And Determinants of Incidence Infection of COVID-19 |
Coronavirus disease 19 infection, SARS coronavirus infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fundacion Teofilo Hernando |
|
Spain |
2020-03-23 |
2020-09-20 |
AMADIICH, NCT04326400 |
Phase Not Applicable |
Recruiting |
1 |
5 Months |
1000 |
Artuto García, Joan Soriano, MD, PhD, Marcos Maroto |
2020-03-31 |
| A single-center, open-label, randomized, and controlled trial of darunavir and cobicistat (DRV/c) in treating laboratory-confirmed COVID-19 patients |
Coronavirus disease 19 infection |
darunavir + cobicistat (fixed dose, HIV infection), Janssen R&D/ Gilead alone |
Cytochrome P450 3 inhibitor, HIV-1 protease inhibitor |
|
Johnson & Johnson |
|
China |
|
|
|
Phase 2 Clinical |
Status not specified |
1 |
|
30 |
|
2020-03-31 |
| Effect of metformin in COVID-19 mortality rate and symptom improvement |
Coronavirus disease 19 infection |
metformin hydrochloride alone, standard regimen therapy alone |
AMP activated protein kinase stimulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tabriz University of Medical Sciences |
|
Iran |
2020-03-20 |
|
IR.TBZMED.REC.1398.1310, IRCT20160310026998N11 |
Phase 3 Clinical |
Recruiting |
1 |
|
200 |
Saba Ghaffary |
2020-03-31 |
| Effect of vitamin A in patients with COVID-19 |
Coronavirus disease 19 infection |
vitamin A alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tabriz University of Medical Sciences |
|
Iran |
2020-04-03 |
|
IR.TBZMED.REC.1398.1305, IRCT20170117032004N3 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
30 |
Dr. Mohammad Sameiee, Zeinab Niknaiz, Zeinab Nikniaz |
2020-03-31 |
| An adaptive phase II/III, randomized, double-blind, placebo-controlled, study assessing efficacy and safety of sarilumab for hospitalized patients with COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
sarilumab alone, supportive care alone |
IL-6 receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sanofi-Aventis Research and Development |
|
France, Italy, Spain, Russian Federation, Germany, Canada |
2020-03-26 |
|
2020-001162-12, EFC16844, U1111-1249-6021 |
Phase 2/Phase 3 Clinical |
Recruiting |
6 |
|
460 |
Sanofi-Aventis Deutschland GmbH, Sanofi-aventis France |
2020-03-31 |
| Proflaxis Using Hydroxychloroquine Plus Vitamins-Zinc During COVID-19 Pandemia |
Coronavirus disease 19 infection |
Variable regimens including Plaquenil , vitamin A , vitamin C , vitamin D , zinc |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Istinye Universitesi |
|
Turkey |
2020-03-20 |
2020-09-01 |
2020-2/1, NCT04326725 |
Phase Not Applicable |
Recruiting |
1 |
5 Months |
80 |
Istinye University M ozmen, Prof, Mahir M Ozmen, Professor, Mehmet Mahir Ozmen |
2020-03-31 |
| COVIDL1: A Study to Investigate the Efficacy of Tradipitant in Treating Severe or Critical COVID-19 Infection |
Coronavirus disease 19 infection, Lung injury |
tradipitant alone |
NK1 receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Vanda Pharmaceuticals Inc |
|
|
2020-04-01 |
2020-08-31 |
COVIDL1, NCT04326426, VLY-686-3501 |
Phase 3 Clinical |
Not yet recruiting |
0 |
5 Months |
300 |
Vasilios Polymeropoulos, MD |
2020-03-31 |
| HYCOVID: Hydroxychloroquine Versus Placebo in Patients Presenting COVID-19 Infection and at Risk of Secondary Complication: a Prospective, Multicenter, Randomized, Double-blind Study |
Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia |
hydroxychloroquine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital, Angers |
|
|
2020-04-30 |
2020-09-30 |
49RC20_0071, HYCOVID, NCT04325893 |
Phase 3 Clinical |
Not yet recruiting |
0 |
5 Months |
1300 |
Béatrice GABLE, Vincent DUBEE |
2020-03-31 |
| A trial to evaluate transplantation of ACE2-mesenchymal stem cells in patients diagnosed with COVID-19 pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
ACE2-mesenchymal stem cells alone |
|
|
Celltex Therapeutics Corp |
|
China |
|
|
|
Phase 2 Clinical |
Status not specified |
1 |
|
7 |
|
2020-03-31 |
| A retrospective study of clinical characteristics and prognosis of novel coronavirus pneumonia (COVID-19) patients with myocardial injury |
Coronavirus disease 19 infection, Heart injury, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
China-Japan Union Hospital of Jilin University, Tongji Hospital, Huazhong University of Science and Technology |
Jilin Provincial Science & Technology Department |
China |
2020-03-27 |
2020-04-27 |
ChiCTR2000031301 |
Phase Not Applicable |
Not yet recruiting |
2 |
1 Month |
100 |
Si Daoyuan |
2020-03-31 |
| A trial to evaluate human umbilical cord mesenchymal stem cells for the treatment of COVID-19 patients |
Coronavirus disease 19 infection |
allogenic human umbilical cord mesenchymal stem cells alone |
|
Female |
Chinese Academy of Sciences |
|
|
|
|
|
Phase 2 Clinical |
Status not specified |
0 |
|
1 |
|
2020-03-31 |
| Safety and Efficacy Study of Allogeneic Human Dental Pulp Mesenchymal Stem Cells to Treat Severe novel coronavirus pneumonia (COVID-19) patients |
Coronavirus disease 19 infection, Viral pneumonia |
allogeneic human dental pulp mesenchymal stem cells alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Renmin Hospital of Wuhan University |
|
China |
2020-04-01 |
2020-07-31 |
ChiCTR2000031319 |
Phase 2 Clinical |
Not yet recruiting |
1 |
4 Months |
20 |
Dr. Chenliang Zhou, Prof Qingsong Ye |
2020-03-31 |
| A randomized, open, parallel-controlled clinical trial on the efficacy and safety of Jingyebaidu granules in treating novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Jinyebaidu granule alone, routine treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tongji Hospital, Union Hospital Tongji Medical School Huazhong University Of Science & Technology |
|
China |
2020-02-12 |
2020-05-30 |
ChiCTR2000029755, ChiMCTR2000002999 |
Phase 4 Clinical |
Recruiting |
1 |
3 Months |
120 |
Chen Qian, Liu Dong |
2020-03-31 |
| Risk factors of death from coronavirus disease 2019 |
Coronavirus disease 19 infection, SARS coronavirus infection |
|
|
|
Yokohama City University |
|
Japan |
2020-03-28 |
|
UMIN000039986 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
|
Nobuyuki Horita |
2020-03-31 |
| Study for the Effect of Novel Coronavirus Pneumonia (COVID-19) on the Health of Different People |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Healthy volunteers accepted |
Sichuan University, West China Hospital |
|
China |
2020-02-10 |
2022-02-10 |
ChiCTR2000029754 |
Phase Not Applicable |
Recruiting |
1 |
24 Months |
1500 |
Chen Lei, Lai Wanlin |
2020-03-31 |
| Effectiveness and safety of hydroxychloroquine sulfate in the preventive treatment of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
hydroxychloroquine alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Shanghai Public Health Clinical Center |
|
China |
2020-03-23 |
2020-09-30 |
ChiCTR2000031174 |
Phase Not Applicable |
Not yet recruiting |
1 |
6 Months |
1000 |
Lu Shuihua, Xia Lu |
2020-03-31 |
| Evaluation of the effectiveness of Ipecac homeopathic remedy in control of Clinical manifestations of COVID-19 |
Coronavirus disease 19 infection |
alcohol plus ipecac homeopathic remedy with C30 potency, Hellios homeopathy pharmacy |
|
|
Iran University of Medical Sciences |
|
Iran |
2020-04-03 |
|
IR.IUMS.REC.1399.039, IRCT20140907019073N4 |
Phase 3 Clinical |
Not yet recruiting |
2 |
|
60 |
Ali Mazaherinezhad, Farbod Rahnama Chitsaz, Proffessor A.Motevalian, Somaye Mahroozade |
2020-03-31 |
| Persian Medicine Products in Covid-19 |
Coronavirus disease 19 infection |
Iranian medicine syrup intake alone, standard treatment alone, Variable regimens including Marticaria chamomilla , Mentha spp , Punicagranatum , Rheum officinale , Zattaria multiflora , Zizyphus sativa , nepeta bracteata , nigella Sativa |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tabriz University of Medical Sciences |
|
Iran |
2020-04-03 |
|
IR.TBZMED.REC.1398.1318, IRCT20140617018126N2 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
60 |
Hojjat Pourfathi Nematabad, Mohammad Samiei |
2020-03-31 |
| A medical records based retrospective study for novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Wuhan third Hospital |
|
China |
2020-03-23 |
2020-04-30 |
ChiCTR2000031187 |
Phase Not Applicable |
Not yet recruiting |
1 |
1 Month |
1292 |
Pengcheng Luo, Yilin Yin |
2020-03-31 |
| Efficacy and optimization of antiviral therapy for novel coronavirus pneumonia (COVID-19) patients |
Coronavirus disease 19 infection, Viral pneumonia |
interferon plus lopinavir + ritonavir |
HIV protease inhibitor |
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
302 Military Hospital of China |
|
China |
2020-01-10 |
2020-12-31 |
ChiCTR2000031196 |
Phase 2 Clinical |
Recruiting |
1 |
11 Months |
90 |
Zhe Xu |
2020-03-31 |
| Clinical features and prognosis of invasive mechanical ventilation patients with novel coronavirus pneumonia (COVID-19) in Wuhan, China: a single-centered, retrospective, observational study |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Renmin Hospital of Wuhan University |
|
China |
2020-03-26 |
2020-04-06 |
ChiCTR2000031227 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
|
Qianqian Qiao, Qingta Meng |
2020-03-31 |
| Shedding virus and functional prognosis in patients with novel coronavirus pneumonia (COVID-19): a medical records based study |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tongji Hospital, Huazhong University of Science and Technology |
|
China |
2020-03-25 |
2020-08-25 |
ChiCTR2000031244 |
Phase Not Applicable |
Not yet recruiting |
1 |
5 Months |
200 |
Shabei Xu, Wei Wang |
2020-03-31 |
| Epidemiologic and Clinical Characteristics of novel coronavirus pneumonia (COVID-19) in surgical patients: a medical records based retrospective study |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
Renmin Hospital of Wuhan University |
|
China |
2020-01-25 |
2020-03-12 |
ChiCTR2000031245 |
Phase Not Applicable |
Recruiting |
1 |
1 Month |
2000 |
Jiabao HOU |
2020-03-31 |
| A clinical study of ACE-MAB to potentially treat COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
ACE-MAB (COVID-19), Mabpharm alone |
|
|
Sorrento Therapeutics Inc |
Mabpharm Ltd |
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-03-31 |
| A clinical study to assess efficacy of alpha-1 antitrypsin in the treatment of patients with COVID-19 |
Coronavirus disease 19 infection |
alpha-1 antitrypsin alone |
|
|
Grifols SA |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-03-31 |
| A clinical study to assess efficacy of intravenous immunoglobulin in the treatment of patients with COVID-19 |
Coronavirus disease 19 infection |
immunoglobulin alone |
|
|
Grifols SA |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-03-31 |
| Epidemiological survey of close contacts of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
Chongqing Medical University |
|
China |
2020-03-01 |
2021-04-30 |
ChiCTR2000031246 |
Phase Not Applicable |
Not yet recruiting |
2 |
14 Months |
|
Kun Chu, Xiaojun Tang |
2020-03-31 |
| Study on the mental state of medical staff during the epidemic period of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
West China Hospital |
|
China |
2020-03-01 |
2021-03-01 |
ChiCTR2000031247 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
500 |
Qingqing Xiao, Xiandong Meng |
2020-03-31 |
| Outcomes and infectivity of patients with asymptomatic novel coronavirus (COVID-19) infection |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
Chongqing Medical University |
|
China |
2020-01-29 |
2020-06-30 |
ChiCTR2000031252 |
Phase Not Applicable |
No longer recruiting |
2 |
5 Months |
60 |
Qiuling Shi, Yang Pu |
2020-03-31 |
| Epidemiological study of novel coronavirus infection (COVID-19) in children at medium/low risk |
Coronavirus disease 19 infection, SARS coronavirus infection |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Tongji Hospital, Huazhong University of Science and Technology |
|
China |
2020-03-16 |
2020-05-16 |
ChiCTR2000031293 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
240 |
Xiaoping Luo, Xiuyun Zhou, Yan Hao |
2020-03-31 |
| The effect of Trachyspermum copticum syrup on clinical manifestations of patients with COVID-19 |
Coronavirus disease 19 infection |
Trachyspermum copticum syrup alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Arak University of Medical Sciences and Health Services |
|
Iran |
2018-04-09 |
|
IR.ARAKMU.REC.1398.342, IRCT20180610040049N3 |
Phase 3 Clinical |
No longer recruiting |
1 |
|
60 |
Alireza Kamali, Seied Amirhosein Latifi |
2020-03-31 |
| A medical records based study for clinical features of novel coronavirus pneumonia (COVID-19) patients and risk factors of death |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The First College Of Clinical Medical Science, China Three Gorges University |
|
China |
2020-01-14 |
2020-03-19 |
ChiCTR2000031296 |
Phase Not Applicable |
No longer recruiting |
1 |
2 Months |
200 |
Zhang Rong, Zhou Fating |
2020-03-31 |
| Clinical Evaluation of Cordio Application in Adult COVID-19 Virus Positive Patients |
Coronavirus disease 19 infection, Viral pneumonia |
Cordio App (Cordio Medical Ltd) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cordio Medical Ltd |
|
Israel |
2020-04-30 |
2021-09-30 |
COV001, NCT04325048 |
Phase Not Applicable |
Not yet recruiting |
1 |
17 Months |
5000 |
Miri Yafee, MSc, Zaher Azzam, Prof |
2020-03-30 |
| Efficacy and Safety of Emapalumab and Anakinra in Reducing Hyperinflammation and Respiratory Distress in Patients With COVID-19 Infection |
Coronavirus disease 19 infection, Respiratory distress syndrome |
anakinra alone, emapalumab alone |
Interferon gamma ligand inhibitor, Type I IL-1 receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Swedish Orphan Biovitrum AB |
|
Italy |
2020-03-31 |
2020-09-30 |
2020-001167-93, NCT04324021, SOBI.IMMUNO-101 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
4 |
6 Months |
54 |
Antonio Pesenti, Prof, Cristina de Min, MD / CMO, Emanuele Nicastri, Dr, Emanuele Nicastri, MD, Franco Franceschini, Prof, Gabriele Missale, Prof, Karin Becker, MSc, Prof |
2020-03-31 |
| VIRUS: Viral Infection and Respiratory Illness Universal Study [VIRUS]: COVID19 Registry |
Coronavirus disease 19 infection |
|
|
|
Mayo Clinic Foundation |
|
US |
2020-04-01 |
2021-04-30 |
20-002610, NCT04323787, VIRUS |
Phase Not Applicable |
Recruiting |
0 |
13 Months |
50000 |
Ayan Sen, MD, Devang Sanghavi, MD, Ognjen Gajic, MD, Rahul Kashya, MBBS, Rahul Kashyap |
2020-03-30 |
| ACT COVID19: Anti-Coronavirus Therapies to Prevent Progression of Coronavirus Disease 2019 (COVID-19) Trial |
Coronavirus disease 19 infection |
azithromycin plus chloroquine |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Population Health Research Institute |
|
Canada |
2020-04-01 |
2020-12-31 |
ACT COVID19, NCT04324463, PHRI.ACT.COVID19 |
Phase 3 Clinical |
Not yet recruiting |
1 |
9 Months |
1500 |
ACT COVID-19 Study Coordinator, Emilie Belley-Cote, MD PhD, Richard Whitlock, MD PhD |
2020-03-30 |
| CYCOV: Cytokine Adsorption in Severe COVID-19 Pneumonia Requiring Extracorporeal Membrane Oxygenation |
Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia |
CytoSorb adsorber alone, Extracorporeal Membrane Oxygenation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Klinikum der Albert-Ludwigs Universitaet Freiburg |
|
Germany |
2020-04-01 |
2020-12-01 |
CYCOV, CYCOV, CYCOV_ECMO_2020, NCT04324528 |
Phase Not Applicable |
Recruiting |
1 |
8 Months |
30 |
Alexander Supady, Dr., MPH |
2020-03-31 |
| CORIMUNO-19: Cohort, Multiple-Randomized, Controlled Trials, Open-label of Immune Modulatory Drugs and Other Treatments in COVID-19 Patients |
Coronavirus disease 19 infection, Viral pneumonia |
immune modulatory drug therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assistance Publique Hopitaux de Paris |
|
|
2020-03-26 |
2021-12-31 |
2020-001246-18, APHP200375, CORIMUNO-19, NCT04324047 |
Phase Not Applicable |
Not yet recruiting |
0 |
21 Months |
1000 |
Matthieu RESCHE-RIGON, MD PhD, Olivier HERMINE, MD-PhD |
2020-03-30 |
| CORONADO: 'Coronavirus SARS-CoV2 and Diabetes Outcomes' |
Coronavirus disease 19 infection, Diabetes mellitus |
antidiabetic treatment alone, antihypertensive treatment alone |
|
|
CHU De Nantes |
|
|
2020-03-30 |
2020-05-08 |
CORONADO, NCT04324736, RC20_0148 |
Phase Not Applicable |
Not yet recruiting |
0 |
1 Month |
300 |
Bertrand Cariou, Pr |
2020-03-30 |
| CORIMUNO-SARI: Cohort, Multiple, Randomized, Controlled Trials, Open-label of Immune Modulatory Drugs and Other Treatments in COVID-19 Patients - Sarilumab Trial |
Coronavirus disease 19 infection, Lung disease, Viral pneumonia |
sarilumab alone |
IL-6 receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assistance Publique Hopitaux de Paris |
|
France |
2020-03-26 |
2021-12-31 |
APHP200375-2, CORIMUNO-SARI, NCT04324073 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
21 Months |
180 |
Matthieu RESCHE-RIGON, MD PhD, Olivier HERMINE, MD-PhD, matthieu resche-rigon, MD-PhD, olivier HERMINE, MD PHD |
2020-03-30 |
| A Study of a Candidate COVID-19 Vaccine |
Coronavirus disease 19 infection |
ChAdOx1 nCoV-19 alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
University of Oxford |
|
UK |
2020-03-31 |
2021-05-31 |
COV001, NCT04324606 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
4 |
14 Months |
510 |
Andrew Pollard, Prof, Volunteer Recruitment Co-ordinator |
2020-03-30 |
| Efficacy and Safety Human Coronavirus Immune Plasma (HCIP) versus Control (SARS-CoV-2 Non-immune Plasma) Among Adults Exposed to COVID-19 |
Coronavirus disease 19 infection, SARS coronavirus infection |
anti-SARS-CoV-2 plasma alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sidney Kimmel Comprehensive Cancer Center |
|
|
2020-04-01 |
2023-01-31 |
CSSC-001, IRB00245634, NCT04323800 |
Phase 2 Clinical |
Not yet recruiting |
0 |
34 Months |
150 |
Darin Ostrander, PhD, Obi Ezennia, MPH |
2020-03-30 |
| PRIORITY: Pregnancy Coronavirus Outcomes Registry |
Coronavirus disease 19 infection |
|
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of California San Francisco |
University of California Los Angeles |
US |
2020-03-20 |
2024-03-31 |
20-30410, NCT04323839, PRIORITY |
Phase Not Applicable |
Recruiting |
0 |
48 Months |
1000 |
Ruth Gebrezghi, Study Coordinator, Vanessa Monzon, Vanessa Vacoby, MD, MAS |
2020-03-31 |
| EC-COVID-PCS: Early CPAP in COVID Patients With Respiratory Failure: a Prospective, Cohort Study |
Coronavirus disease 19 infection, Respiratory failure |
ACE inhibitor therapy alone, antiviral therapy alone, sartans therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Istituto di Ricerche Farmacologiche Mario Negri |
|
Italy |
2020-04-06 |
2021-11-09 |
EC-COVID-PCS, EC-COVID-PCS-FENICE, NCT04323878 |
Phase Not Applicable |
Not yet recruiting |
1 |
19 Months |
3000 |
|
2020-03-31 |
| The investigation on medical adhesive-related skin injury caused by protective dressings of medical staffs during the period of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
Nanjing Drum Tower Hospital |
|
|
2020-01-01 |
2021-01-01 |
ChiCTR2000031324 |
Phase Not Applicable |
Not yet recruiting |
0 |
12 Months |
300 |
Wei Min |
2020-03-31 |
| Convalescent Plasma to Limit Coronavirus Associated Complications |
Coronavirus disease 19 infection |
c,anti-SARS-CoV-2 onvalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Mayo Clinic Foundation |
|
US |
2020-04-01 |
2022-12-31 |
20-002864, NCT04325672 |
Phase 2a Clinical |
Not yet recruiting |
0 |
33 Months |
20 |
Michael Joyner, MD, Shelly Roberts, RN |
2020-03-31 |
| A prospective, randomized, open-label, controlled clinical study to evaluate the preventive effect of hydroxychloroquine on close contacts after exposure to the Novel Coronavirus Pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
hydroxychloroquine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Renmin Hospital of Wuhan University |
|
China |
2020-02-20 |
2021-02-20 |
ChiCTR2000029803 |
Phase 0 Clinical |
Not yet recruiting |
1 |
12 Months |
320 |
Shoumeng Han, Zhan Zhang |
2020-03-31 |
| Prevalence and Incidence of COVID-19 Infection in Patients With Chronic Plaque Psoriasis on Immunosuppressant Therapy |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Universita di Verona |
Azienda Ospedaliera Universitaria Integrata Di Verona |
Italy |
2020-04-01 |
2020-12-31 |
GISONDI 4, NCT04324866 |
Phase Not Applicable |
Not yet recruiting |
1 |
9 Months |
300 |
Paolo Gisondi |
2020-03-31 |
| A clinical study to assess anti-SARS-CoV-2 hyperimmune globulin therapy as a therapy for the treatment of patients with COVID-19 disease |
Coronavirus disease 19 infection |
hyperimmune globulin alone |
|
|
Grifols SA |
Biomedical Advanced Research and Development Authority (BARDA), Food and Drug Administration |
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-03-31 |
| Comparison of vitamin D3 and N-acetylcysteine prescription in COVID-19 patients and their effect on recovery process |
Coronavirus disease 19 infection |
N acetylcysteine alone, Vitamin D3 alone, standard treatment alone, N acetylcysteine plus Vitamin D3 |
|
|
Abadan School of Medical Sciences |
|
Iran |
2020-03-29 |
|
IR.ABADANUMS.REC.1398.118, IRCT20200324046850N1 |
Phase 3 Clinical |
Recruiting |
1 |
|
100 |
Sara Mobarak |
2020-03-30 |
| Efficacy of the myrtle syrup in the treatment of novel corona |
Coronavirus disease 19 infection, Viral pneumonia |
myrtle (Myrtus Communis) syrup alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Kerman University of Medical Sciences |
|
Iran |
2020-04-02 |
|
IR.KMU.REC.1399.015, IRCT20180923041093N3 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
100 |
Abbas Pardakhti, Maryam Azimi |
2020-03-30 |
| Shen-Fu injection in the treatment of severe novel coronavirus pneumonia (COVID-19): a multicenter, randomized, open-label, controlled trial |
Coronavirus disease 19 infection, Viral pneumonia |
Shen-Fu injection alone, conventional treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Peking University Third Hospital |
|
China |
2020-02-01 |
2020-12-31 |
ChiCTR2000030043 |
Phase 4 Clinical |
Not yet recruiting |
14 |
11 Months |
300 |
Ma Penglin, Wang Zongyu |
2020-03-31 |
| A Medical Records Based Retrospective Study for Clinical Characteristics of severe Novel Coronavirus Pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Xiangya Hospital Of Central South University |
|
China |
2020-03-24 |
2020-05-31 |
ChiCTR2000031199 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
150 |
Fan Rong, Wang Yang |
2020-03-31 |
| Study for the effect of Moxibustion Guidance and Intervention based on internet for the discharged patients with novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
moxibustion treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
People’s Hospital of Zhengzhou |
|
China |
2020-03-01 |
2022-02-28 |
ChiCTR2000031203, ChiMCTR2000003156 |
Phase 0 Clinical |
Recruiting |
1 |
24 Months |
28 |
Fu Liran |
2020-03-31 |
| Cancelled by the investigator A clinical study for 'Huo-Shen' particles in the treatment of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Huo-Shen particles alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shenzhen national medicine inheritance medical research institute co. LTD |
|
China |
2020-03-24 |
|
ChiCTR2000030118, ChiMCTR2000003048 |
Phase 0 Clinical |
Terminated |
1 |
|
120 |
Yuan Yongming, Zhang Jingsha |
2020-03-31 |
| Cancelled by the investigator Humanistic Care in Patients With Novel Coronavirus Pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
psychological and physical rehabilitation based humanistic care alone, routine regimen alone |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The Second Hospital of Xi'An Jiaotong University |
|
China |
2020-02-24 |
|
ChiCTR2000030136 |
Phase 0 Clinical |
Terminated |
1 |
|
130 |
Gong Shouping, Ma Xiaorong |
2020-03-31 |
| Efficacy of the barley-based remedy in the treatment of novel corona |
Coronavirus disease 19 infection, Viral pneumonia |
barley-based medication alone, drug pack therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Kerman University of Medical Sciences |
|
Iran |
2020-04-02 |
|
IR.KMU.REC.1399.014, IRCT20180923041093N4 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Abbas Pardakhti, Maryam Azimi |
2020-03-30 |
| Cancelled by the investigator Humanistic Care in Healthcare Workers in Novel Coronavirus Pneumonia (COVID-19) |
Coronavirus disease 19 infection, Depression, Post traumatic stress disorder, Viral pneumonia |
humanistic care alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
The Second Hospital of Xi'An Jiaotong University |
|
China |
2020-02-24 |
|
ChiCTR2000030137 |
Phase 0 Clinical |
Terminated |
1 |
|
130 |
Gong Shouping, Ma Xiaorong |
2020-03-30 |
| Quality of life among Chinese residents during and after novel coronavirus pneumonia (COVID-19) outbreak: an online survey |
Coronavirus disease 19 infection, Viral pneumonia |
health advice based on online survey alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry |
The Jockey Club School of Public Health and Primary Care |
|
China |
2020-02-20 |
2022-05-19 |
ChiCTR2000030223 |
Phase Not Applicable |
Recruiting |
1 |
27 Months |
5000 |
Daisy Dexing Zhang |
2020-03-30 |
| Efficacy evaluation of an herbal compound 'Fluherb' on clinical symptoms and paraclinical parameters in highly suspected COVID-19 patients: a controlled, randomized clinical trial |
Coronavirus disease 19 infection |
Fluherb supplement alone |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Mashhad University of Medical Sciences |
|
Iran |
2020-03-28 |
|
IR.MUMS.REC.1398.315, IRCT20200323046841N1 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
|
30 |
Dr. Mohsen Tafaghodi, Mahdi Yousefi |
2020-03-30 |
| Clinical study for the effects of ACEIs/ARBs on the infection of novel coronavirus pneumonia (CoVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
angiotensin II receptor blockers (ARBs) alone, angiotensin-converting enzyme inhibitors (ACEIs) alone |
|
|
The First Affiliated Hospital of Wenzhou Medical University |
|
China |
2020-03-02 |
|
ChiCTR2000030453 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Yanling Shi |
2020-03-30 |
| JYCO: A multicenter, single-blind, randomized, controlled clinical trial for chloroquine phosphate in the treatment of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
chloroquine phosphate alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Beijing Institute of Pharmacology and Toxicology, Beijing YouAn Hospital |
|
China |
2020-01-30 |
|
ChiCTR2000031204, JYCO, JYCO |
Phase 2 Clinical |
Recruiting |
3 |
|
300 |
Jin Ronghua, Zhong Wu |
2020-03-30 |
| Clinical study on the correlation between novel coronavirus pneumonia (COVID-19) clinical rehabilitation assessment and prognosis |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The First Rehabilitation Hospital of Shanghai, Wuhan third Hospital |
|
China |
2020-03-31 |
2022-03-31 |
ChiCTR2000031214 |
Phase 0 Clinical |
Not yet recruiting |
1 |
24 Months |
60 |
GAO Tian-lin, ZHOU Zhe |
2020-03-31 |
| Clinical Application of ECMO in the Treatment of Patients with Very Serious Respiratory Failure due to novel Coronavirus Pneumonia (COVID-19) |
Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia |
extracorporeal membrane oxygenation (ECMO) alone |
|
|
Capital Medical University, Wuhan Jinyintan Hospital |
Ministry of Science and Technology of the People´s Republic of China |
China |
2020-02-01 |
2021-01-31 |
ChiCTR2000029804 |
Phase Not Applicable |
Recruiting |
3 |
12 Months |
100 |
Liu Ying, Wu Wenjuan |
2020-03-31 |
| The effect of stem cell transplantation in the treatment of COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
cord-derived mesenchymal stem cells (SinaCell) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
MOM research and innovation center |
|
Iran |
2020-03-24 |
|
IR.IUMS.REC.1398.1400, IRCT20140528017891N8 |
Phase 3 Clinical |
Recruiting |
1 |
|
10 |
Amirhossein Asgary, Elham Jamshidi, Nader Tavakoli, Omid Moradimoghadam |
2020-03-30 |
| DEXA-COVID19: Efficacy of Dexamethasone Treatment for Patients With ARDS Caused by COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
dexamethasone (Indukern) alone, standard intensive care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Dr. Negrin University Hospital |
Li Ka Shing Knowledge Institute |
Spain |
2020-04-01 |
2020-10-30 |
2020-001278-31, DEXA-COVID19, NCT04325061 |
Phase 4 Clinical |
Not yet recruiting |
1 |
6 Months |
200 |
Arthur Slutsky, MD, Jesús Villar, MD |
2020-03-31 |
| Comparison of the Effect of Sofosbuvir + Daclatasvir (Sovodac) and Ribavirin in Covid-19 |
Coronavirus disease 19 infection |
daclatasvir+ sofosbuvir alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Abadan School of Medical Sciences |
|
Iran |
2020-03-18 |
|
IR.ABADANUMS.REC.1398.113, IRCT20200324046850N2 |
Phase 2 Clinical |
Recruiting |
1 |
|
60 |
Sara Mobarak, Sara Mobark |
2020-03-31 |
| ENACOVID: Efficacy of Addition of Naproxen in the Treatment of Critically Ill Patients Hospitalized for COVID-19 Infection |
Coronavirus disease 19 infection, Viral pneumonia |
Standard of care alone, naproxen alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assistance Publique Hopitaux de Paris |
|
France |
2020-03-27 |
2021-06-27 |
APHP200387, ENACOVID, NCT04325633 |
Phase 3 Clinical |
Not yet recruiting |
1 |
15 Months |
584 |
Anny SLAMA SCHWOK, MD, Frédéric ADNET, MD, PhD |
2020-03-31 |
| CAPACITY-COVID: Cardiac Complications in Patients With SARS Coronavirus 2 Registry |
Cardiovascular disease, Coronavirus disease 19 infection, SARS coronavirus infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universitair Medisch Centrum Utrecht |
|
Netherlands |
2020-03-23 |
2021-06-23 |
20-161/C, CAPACITY-COVID, NCT04325412 |
Phase Not Applicable |
Recruiting |
1 |
15 Months |
1000 |
Folkert W. Asselbergs, MD, PhD, Marijke Linschoten, MD, Prof. Dr. F.W. Asselbergs |
2020-03-31 |
| Recommendations of Integrated Traditional Chinese and Western Medicine for Novel Coronavirus Pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Western medicine therapy alone, traditional Chinese medicine therpy alone |
|
|
The Affiliated Hospital of Chengdu University of Traditional Chinese Medicine |
Science & Technology Department of Sichuan Province |
China |
2020-02-03 |
2020-05-01 |
ChiCTR2000029549, ChiMCTR2000002983 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
400 |
Tang Shiyun, Xie Chunguang |
2020-03-31 |
| A clinical study to assess Ampligen for the potential treatment of COVID-19 |
Coronavirus disease 19 infection |
|
|
|
AIM ImmunoTech Inc |
National Institute of Infectious Diseases Japan |
Japan |
|
|
|
Phase Not Applicable |
Not yet recruiting |
2 |
|
|
Dr. Hideki Hasegawa, Dr. Takeshi Ichinohe |
2020-03-30 |
| Chinese medicine prevention and treatment program for novel coronavirus pneumonia (COVID-19): a perspective, sing-arm trial |
Coronavirus disease 19 infection, Viral pneumonia |
traditional Chinese medicine therapy alone, western medicine therapy alone |
|
|
Zhejiang Chinese Medical University |
|
China |
2020-02-06 |
2020-04-30 |
ChiCTR2000029578 |
Phase 0 Clinical |
Recruiting |
1 |
2 Months |
1000 |
Chengping Wen, Zhijun Xie |
2020-03-30 |
| DAS-181 for COVID-19: Compassionate Use |
Coronavirus disease 19 infection, SARS coronavirus infection |
DAS-181 alone |
Exo-alpha sialidase modulator, Muscarinic receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Renmin Hospital of Wuhan University |
Ansun BioPharma Inc |
China |
2020-03-06 |
2020-04-30 |
DAS181-SARS-COV-2, NCT04324489 |
Phase 2 Clinical |
Recruiting |
1 |
1 Month |
4 |
Kejx Hu, MD, Zuojiong Gong, MD, Zuojiong Guong, MD |
2020-03-30 |
| Clinical characteristics and death risk factors in severe novel coronavirus pneumonia (COVID-19) patients: a single-center respective analysis based on medical records |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tongji Medical College |
|
China |
2020-04-01 |
2020-04-10 |
ChiCTR2000031327 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
120 |
Hong Qiu, Hui Peng |
2020-03-30 |
| A Retrospective Study for Preventive Medication in Tongji Hospital During the Epidemic of Novel Coronavirus Pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Jinyebaidu granule alone, angiotensin II receptor blockers therapy alone, other prophylactic drugs therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tongji Hospital, Huazhong University of Science and Technology |
|
China |
2020-02-12 |
2020-05-30 |
ChiCTR2000029728 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
500 |
Chen Qian, Liu Dong |
2020-03-31 |
| The protective effect of sleep psychology and music therapy of novel coronavirus pneumonia (COVID-19) mild and moderate type patients |
Coronavirus disease 19 infection, Viral pneumonia |
basic therapy alone, sleep-aid music therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine |
|
China |
2020-03-13 |
2020-04-30 |
2020003, ChiCTR2000031328 |
Phase Not Applicable |
Recruiting |
1 |
1 Month |
60 |
Yuan-hao Wu |
2020-03-30 |
| NIKE-C19: Prognostic Factors Keeping Track for Covid19 Pneumonia |
Cardiovascular disease, Chronic obstructive pulmonary disease, Coronavirus disease 19 infection, Hypertension, Non-insulin dependent diabetes, Obesity, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Catholic University of the Sacred Heart |
|
Italy |
2020-04-03 |
2020-06-30 |
20202503, NCT04324684, NIKE-C19 |
Phase Not Applicable |
Not yet recruiting |
1 |
2 Months |
198 |
Geltrude Mingrone |
2020-03-30 |
| A pilot study to diagnose COVID-19 in subject obtained oropharyngeal and salivary samples through FDA approved gold standard of COVID-19 testing |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
ZoomCare Company |
PeaceHealth System Services |
US |
|
|
|
Phase Not Applicable |
Recruiting |
0 |
|
|
|
2020-03-30 |
| Epidemiological investigation and clinical characteristics analysis of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
The First People's Hospital of Huaihua |
Hunan Provincial Natural Science Foundation |
China |
2020-01-31 |
2020-08-07 |
ChiCTR2000029734 |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
40 |
Chengfeng Qiu |
2020-03-31 |
| The effect of Gymnastic Qigong Yangfeifang on functional recovery and quality of life in patients with mild novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Qigong Yangfeifang alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Shanghai Public Health Clinical Center, Shanghai University of Traditional Chinese Medicine, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Shanghai University of Traditional Chinese Medicine |
|
China |
2020-02-18 |
2022-02-19 |
ChiCTR2000029976, ChiMCTR2000003032 |
Phase 0 Clinical |
Recruiting |
1 |
24 Months |
80 |
Shan Chunlei, Xu Shutian |
2020-03-31 |
| Influence of novel coronavirus pneumonia (COVID-19) on disease activity, medical and mental condition of patients with rheumatic diseases |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Guangdong Provincial People's Hospital |
|
China |
2020-03-11 |
2023-12-31 |
ChiCTR2000031329 |
Phase Not Applicable |
Recruiting |
1 |
45 Months |
120 |
Tianwang Li |
2020-03-31 |
| Expanded Access Treatment Protocol: Remdesivir (RDV; GS-5734) for the Treatment of SARS-CoV2 (CoV) Infection |
Coronavirus disease 19 infection |
remdesivir alone |
RNA polymerase modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Gilead Sciences Inc |
|
|
|
|
GS-US-540-5821, NCT04323761 |
Phase Not Applicable |
Recruiting |
0 |
|
|
Gilead Clinical Study Information Center, Gilead Study Director |
2020-03-31 |
| A medical records based study for risk assessment and treatment timing of invasive fungal infection in novel coronavirus pneumonia (COVID-19) critical patients |
Candida infection, Coronavirus disease 19 infection, Viral pneumonia |
antifungal therapy alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tongji Hospital, Huazhong University of Science and Technology |
|
China |
2020-04-01 |
2020-08-31 |
ChiCTR2000030717 |
Phase Not Applicable |
Not yet recruiting |
3 |
5 Months |
260 |
Minghao Fang, Xiaojing Zou |
2020-03-31 |
| A Phase I/II Study of Universal Off-the-shelf NKG2D-ACE2 CAR-NK Cells for Therapy of COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
ACE2 CAR-NK cells alone, IL-15 NK cells alone, NK cells alone, NKG2D CAR-NK cells alone, NKG2D-ACE2 CAR-NK cells alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Chongqing Infectious Disease Medical Center |
Chongqing Sidemu Biotechnology Co. Ltd |
China |
2020-03-21 |
2020-09-30 |
CHONGQINGPUBLICHMC, NCT04324996 |
Phase 1/Phase 2 Clinical |
Recruiting |
1 |
6 Months |
90 |
Jimin Gao, PhD, Min Liu, A.B |
2020-03-31 |
| AI based prognostic evaluation of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
prognostic evaluation alone |
|
|
Huazhong University of Science and Technology |
|
China |
2020-04-01 |
2021-03-31 |
ChiCTR2000031336 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
|
Fan Yang, Wenliang Fan |
2020-03-31 |
| Retrospective and Prospective Study for Nosocomial infection in Stomatology Department under the Background of novel coronavirus pneumonia (COVID-19) epidemic period |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Male |
Tongji Hospital, Huazhong University of Science and Technology |
|
China |
2020-03-14 |
2020-04-30 |
ChiCTR2000030895 |
Phase 1 Clinical |
Not yet recruiting |
1 |
1 Month |
1000 |
Jingyu Hu, Jingzhi Ma |
2020-03-31 |
| A clinical trial of Standard Q COVID-19 IgM/IgG Rapid Antibody Test for the qualitative presumptive detection of specific IgM and IgG antibodies associated with the 2019 novel coronavirus (SARS-CoV-2) |
Coronavirus disease 19 infection, SARS coronavirus infection |
Standard Q COVID-19 IgM/IgG Rapid Antibody Test alone |
|
|
Henry Schein Inc |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
|
|
2020-03-30 |
| Combined diagnostic value of novel coronavirus (2019-CoV) infection detected by NLR and CRP |
Coronavirus disease 19 infection, Viral pneumonia |
blood routine test alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kongjiang hospital |
|
China |
2020-01-21 |
2020-06-30 |
ChiCTR2000030942 |
Phase Not Applicable |
No longer recruiting |
1 |
5 Months |
191 |
MINGLI LIU |
2020-03-31 |
| Cancelled by investigator A cox regression analysis of prognosis of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Cox regression analysis alone |
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Wuhan Asia General Hospital |
|
China |
2020-02-01 |
2020-02-18 |
ChiCTR2000029820 |
Phase Not Applicable |
Suspended |
1 |
|
410 |
Huang Keqiang |
2020-03-31 |
| Analysis of clinical characteristics of severe novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
Peking Union Medical College Hospital, Wuhan Jinyintan Hospital |
Ministry of Science and Technology of the People´s Republic of China |
China |
2020-01-01 |
2021-01-31 |
ChiCTR2000029805 |
Phase Not Applicable |
Recruiting |
1 |
13 Months |
100 |
Liu Ying, Wu Wenjuan |
2020-03-31 |
| A study for the psychological status, social support, and care needs of tumor patients admitted to a general hospital during the novel coronavirus pneumonia (COVID-19) outbreak |
Cancer, Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fifth Affiliated Hospital, Sun Yat-Sen University |
|
China |
2020-02-14 |
2020-04-12 |
ChiCTR2000029830 |
Phase 0 Clinical |
Not yet recruiting |
1 |
1 Month |
400 |
Hongmei Tao, Weize Lyu |
2020-03-31 |
| Clinical observation and research of severe acute respiratory syndrome coronavirus 2(COVID-19) infection in perinatal newborns |
Coronavirus disease 19 infection, SARS coronavirus infection |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months) |
West China Second University Hospital |
|
China |
2020-01-25 |
2021-01-01 |
ChiCTR2000029959 |
Phase Not Applicable |
Recruiting |
2 |
11 Months |
30 |
Jun Tang |
2020-03-31 |
| Clinical efficacy of TCM syndrome differentiation in the treatment of severe/critical type of novel coronavirus pneumonia (COVID-19): a prospective, observational, one-arm clinical study |
Coronavirus disease 19 infection, Viral pneumonia |
standard treatment alone, traditional chinese medicine alone |
|
|
Chengdu University of Traditional Chinese Medicine |
State Administration of Traditional Chinese Medicine People's Republic of China |
China |
2020-03-01 |
2020-12-31 |
ChiCTR2000030962, ChiMCTR2000003153 |
Phase Not Applicable |
Not yet recruiting |
2 |
10 Months |
60 |
Peiyang Gao, Shikun Deng |
2020-03-31 |
| A Medical Based Retrospective Study for Clinical Characteristics, Treatments and Prognosis of Patients with Novel Coronavirus Pneumonia (COVID-19) in WuHan |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
Shanghai Changzheng Hospital, Wuhan Hankou Hospital |
|
China |
2020-03-01 |
2020-12-31 |
ChiCTR2000030961 |
Phase Not Applicable |
Recruiting |
2 |
10 Months |
2000 |
Miao Yushan, Tang Hao |
2020-03-31 |
| Myocardial injury and arrythmias in the novel coronavirus pneumonia (COVID-19) patients |
Coronavirus disease 19 infection, Heart arrhythmia, Heart injury, Pneumonia |
|
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fifth Affiliated Hospital, Sun Yat-Sen University |
|
China |
2020-01-18 |
2020-04-01 |
ChiCTR2000030952 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
93 |
Chen Jian |
2020-03-30 |
| TOCIVID: Anti-IL6 Treatment of Serious COVID-19 Disease With Threatening Respiratory Failure |
Coronavirus disease 19 infection, Viral pneumonia |
Standard medical care alone, sarilumab alone, tocilizumab (intravenous), Roche/Chugai alone, tocilizumab (subcutaneous), Roche/Chugai alone |
IL-6 receptor antagonist, IL-6 receptor modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Frederiksberg University Hospital |
|
Denmark |
2020-03-25 |
2021-06-01 |
APPI2-CV-2020-01, NCT04322773, TOCIVID |
Phase 2 Clinical |
Not yet recruiting |
1 |
14 Months |
200 |
Lars Erik Kristensen, PhD, Line Rustad |
2020-03-31 |
| An observational study for cardiac and pulmonary ultrasound and evaluation of treatment of severe patients with novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
ultrasound alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Wuhan Union Hospital, China, Xiangya Hospital Of Central South University |
|
China |
2020-03-20 |
2020-05-31 |
ChiCTR2000030919 |
Phase Not Applicable |
Not yet recruiting |
1 |
2 Months |
80 |
Zhang Lina, Zhao Chunguang |
2020-03-30 |
| Evaluation of the effect of taking tricholoma matsutake, cannabis sativa capsule and dendrobium candidum to nutrition intervention of patients with novel coronavirus pneumonia (COVID-19) during convalescence |
Coronavirus disease 19 infection, Viral pneumonia |
dendrobium candidum alone, tricholoma matsutake alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The 2nd People's Hospital of Ningbo |
|
China |
2020-02-01 |
2021-05-01 |
2020YJY0201, ChiCTR2000030920 |
Phase Not Applicable |
Recruiting |
1 |
15 Months |
100 |
Ting Cai |
2020-03-30 |
| Prospective, open-label, controlled, multicenter, cohort study of long-acting interferon plus ribavirin in patients with novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
long-acting interferon alpha-2a plus ribavirin |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
First People's Hospital of Foshan |
|
China |
2020-02-26 |
2020-08-26 |
ChiCTR2000030922 |
Phase 2 Clinical |
Recruiting |
4 |
6 Months |
30 |
Bin Zhang/Yinong Ye, Haiming Yan |
2020-03-30 |
| The treatment and diagnosis plan of integrated traditional Chinese and Western medicine for novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
TCM formula 1 alone, TCM formula 2 alone, TCM formula 3 alone, TCM formula 4 alone, TCM formula 5 alone, TCM formula 6 alone, Western medicine alone |
|
|
The Affiliated Hospital of Shaanxi University of Chinese Medicine |
Shaanxi Provincial Science and Technology Department |
China |
2020-01-15 |
2020-04-16 |
ChiCTR2000030923, ChiMCTR2000003148 |
Phase 0 Clinical |
Recruiting |
1 |
3 Months |
400 |
Lei Genping |
2020-03-30 |
| Hydroxychloroquine for the Treatment of Patients With Mild to Moderate COVID-19 to Prevent Progression to Severe Infection or Death |
Coronavirus disease 19 infection |
hydroxychloroquine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Rambam Health Care Campus |
Rabin Medical Center |
Israel |
2020-03-31 |
2020-12-31 |
0154-20-RMB, NCT04323631 |
Phase 0 Clinical |
Not yet recruiting |
1 |
9 Months |
1116 |
Paul |
2020-03-30 |
| CoV-CONTACT-SERO: Factors Associated With a Positive SARS-CoV-2 Serology in Contact Subjects at High/Moderate Risk of Coronavirus SARS-CoV-2 Infection |
Coronavirus disease 19 infection |
SARS-CoV-2 serology alone, Whole exome sequencing alone |
|
|
INSERM |
|
France |
2020-03-09 |
2020-05-01 |
2020-A00609-30, C20-16, CoV-CONTACT-SERO, NCT04322279 |
Phase Not Applicable |
Recruiting |
1 |
1 Month |
300 |
Bruno Lina, MD, Xavier Duval, MD |
2020-03-30 |
| LUSCOVID19: Simple, Safe, Same: Lung Ultrasound for COVID-19 |
Coronavirus disease 19 infection |
|
|
|
Catholic University of the Sacred Heart |
Fondazione IRCCS Policlinico San Matteo, L'Azienda USL Nord Ovest, Lodi Hospital, Universita Degli Studi di Pavia, University of Trento |
Italy |
2020-04-01 |
2021-01-15 |
0013226/20, LUSCOVID19, NCT04322487 |
Phase Not Applicable |
Not yet recruiting |
9 |
9 Months |
100 |
Andrea Smargiassi, MD, PhD, Gino Soldati, MD, Libertario Demi, PhD, Riccardo Inchingolo, MD, PhD |
2020-03-30 |
| Developing and evaluating of artificial intelligence triage system for suspected novel coronavirus pneumonia (COVID-19): a retrospective study |
Coronavirus disease 19 infection, Viral pneumonia |
artificial intelligence triage system alone |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Infervision, Tianyou hospital, Tongji Medical College, Xianning Central Hospital |
|
China |
2020-03-20 |
2020-06-30 |
ChiCTR2000030951 |
Phase Not Applicable |
Not yet recruiting |
3 |
3 Months |
|
Shabei Xu, Wei Wang |
2020-03-30 |
| CovidSurg: Outcomes of Surgery in COVID-19 Infection: International, Cohort Study |
Coronavirus disease 19 infection |
elective surgery alone |
|
|
The University of Birmingham |
|
|
2020-03-31 |
2020-09-30 |
CS-20200324, CovidSurg, NCT04323644 |
Phase Not Applicable |
Not yet recruiting |
0 |
6 Months |
1000 |
Aneel Bhangu, Dmitri Nepogodiev |
2020-03-30 |
| Study for novel coronavirus pneumonia (COVID-19) patients etiology and immune response and guidance for vaccine design |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
West China Hospital |
|
China |
2020-02-09 |
2022-02-10 |
ChiCTR2000030950 |
Phase 0 Clinical |
Recruiting |
1 |
24 Months |
|
Liujie, Yangqi |
2020-03-30 |
| Traditional Chinese Medicine for Severe COVID-19 |
Coronavirus disease 19 infection |
Traditional Chinese medicine alone, conventional treatment alone |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Xiyuan Hospital China Academy Of Chinese Medical Sciences |
|
China |
2020-03-31 |
2020-04-30 |
2020XLA015-1, NCT04323332 |
Phase 3 Clinical |
Not yet recruiting |
1 |
1 Month |
50 |
Hao Li, Prof., Hao Li, Professor, Li Hao, professor |
2020-03-30 |
| Escin in Patients With Covid-19 Infection (add-on-COV2) |
Coronavirus disease 19 infection, Viral pneumonia |
conventional antiviral drug therapy alone, escin alone, sodium escinate alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Universita' Degli Studi "Magna Graecia" Di Catanzaro |
Azienda Ospedaliera Pugliese Ciaccio, Azienda Ospedaliera Universitaria Mater Domini di Catanzaro |
Italy |
2020-03-23 |
2020-08-30 |
COVID-19 ADD-ON THERAPY, NCT04322344 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
5 Months |
120 |
LUCA GALLELLI, Luca Gallelli |
2020-03-30 |
| Effect of auricular point pressing on insomnia of novel coronavirus pneumonia (COVID-19) patients: a randomized controlled trial |
Coronavirus disease 19 infection, Viral pneumonia |
auricular point pressing alone, normal treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Xiyuan Hospital China Academy Of Chinese Medical Sciences |
|
China |
|
|
ChiCTR2000030996, ChiMCTR2000003137 |
Phase 0 Clinical |
Recruiting |
1 |
|
60 |
Jing Li |
2020-03-27 |
| Efficacy and Safety of Pirfenidone in the Treatment of Severe Post-Novel Coronavirus Pneumonia (COVID-19) Fibrosis: a prospective exploratory experimental medical study |
Coronavirus disease 19 infection, Fibrosis, Viral pneumonia |
pirfenidone alone, routine-life support symptomatic treatment alone |
PDGF receptor antagonist, TGF beta receptor antagonist, p38 MAP kinase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The First Affiliated Hospital of Guangzhou Medical College |
Beijing Pharmaceutical Group Companies |
China |
2020-03-06 |
2020-12-30 |
ChiCTR2000030892 |
Phase 0 Clinical |
Recruiting |
1 |
9 Months |
40 |
Qun Luo |
2020-03-31 |
| Study for effects of crisis intervention based on positive psychology for medical staffs working in the novel coronavirus pneumonia (COVID-19) field |
Coronavirus disease 19 infection, Viral pneumonia |
Positive Psychological Guidance Group Counseling alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
People’s Hospital of Zhengzhou |
|
China |
|
|
ChiCTR2000030893 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
50 |
Wang He |
2020-03-31 |
| The Use of Angiotensin Converting Enzyme Inhibitors and Incident Respiratory Infections, Are They Harmful or Protective? |
Coronavirus disease 19 infection, Influenza virus infection, Respiratory tract infection |
ACE inhibitor therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University College London |
|
|
1998-01-01 |
2020-03-31 |
ISAC17_205R, NCT04322786 |
Phase Not Applicable |
No longer recruiting |
0 |
267 Months |
1302508 |
|
2020-03-30 |
| COLCORONA: Colchicine Coronavirus SARS-CoV2 Trial (COVID-19) |
Coronavirus disease 19 infection, Lung disease |
colchicine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Montreal Health Innovations Coordinating Center, Montreal Heart Institute |
CGI Inc, DACIMA Software, Pharmascience Inc, Quebec government |
Canada |
2020-03-23 |
2020-09-30 |
COLCORONA, MHIPS-2020-001, NCT04322682 |
Phase 3 Clinical |
Recruiting |
1 |
6 Months |
6000 |
Chantal Lacoste, Jean-Claude Tardif, M.D, Jean-Claude Tardif, MD, Zohar Bassevitch, B.SC. |
2020-03-30 |
| A study of peripheral blood T lymphocyte subsets in patients with novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
People’s Hospital of Zhengzhou |
|
China |
2020-03-31 |
2021-03-31 |
ChiCTR2000031115 |
Phase 0 Clinical |
Recruiting |
1 |
12 Months |
30 |
Jiao Xianfa, Wang Hongyu |
2020-03-30 |
| A medical records based study for the value of upper respiratory tract virus detection in the assessment of rehabilitation of novel coronavirus pneumonia (COVID-19) patient |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Renmin Hospital of Wuhan University |
|
China |
2020-03-12 |
2020-06-12 |
ChiCTR2000030993 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
300 |
Binru Wang |
2020-03-30 |
| Study for metagenomics of patients with novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fifth Affiliated Hospital, Sun Yat-Sen University |
|
China |
2020-02-05 |
2020-12-01 |
ChiCTR2000031104 |
Phase Not Applicable |
Recruiting |
1 |
9 Months |
200 |
Pengfei Pang |
2020-03-30 |
| A clinical trial of Vesper, a unique ventilator expansion device, for potential treatment of COVID-19 |
Coronavirus disease 19 infection |
Vesper alone |
|
|
Prisma Health-Upstate |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
|
|
2020-03-27 |
| Analysis for the mental health status of residents in Jingzhou during the outbreak of the novel coronavirus pneumonia (COVID-19) and corresponding influencing factors |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Jingzhou Mental Hospital |
|
China |
2020-02-10 |
2020-04-30 |
ChiCTR2000030902 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
1000 |
Deng Xiaopeng, Zhang Xinfeng |
2020-03-30 |
| Clinical Application and Theoretical Discussion of Fu-Zheng Qing-Fei Thought in Treating Non-Critical Novel Coronavirus Pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Western medicine treatment alone, traditional Chinese medicine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Zhengzhou University |
|
China |
2020-02-06 |
2021-03-30 |
ChiCTR2000030896, ChiMCTR2000003125 |
Phase 0 Clinical |
Recruiting |
1 |
13 Months |
24 |
Wang Dazhong, Yu Zhongling |
2020-03-30 |
| Retrospective analysis of epidemiology and transmission dynamics of patients confirmed with Coronavirus Disease (COVID-19) in Hong Kong |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
Chinese University of Hong Kong |
|
China |
2020-03-09 |
2020-03-14 |
ChiCTR2000030901 |
Phase Not Applicable |
No longer recruiting |
1 |
|
100 |
Peter Choi Ching Lam, Prof. Christopher CK Lai |
2020-03-30 |
| Evaluation on the effect of Chushifangyi prescription in preventing novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Chushifangyi alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Affiliated Hospital of Changchun University of Traditional Chinese Medicine |
|
China |
2020-01-24 |
2020-12-31 |
ChiCTR2000030898, ChiMCTR2000003124 |
Phase Not Applicable |
Recruiting |
2 |
11 Months |
1000 |
Tian Lin, Wang Tan |
2020-03-30 |
| A clinical study of bucillamine for the potential treatment of infectious disease including coronavirus disease (COVID-19) |
Coronavirus disease 19 infection, Infectious disease |
repurposed formulation of bucillamine (gout/cystinuria/Wilson disease), Revive Therapeutics alone |
Xanthine oxidase inhibitor |
|
Pharm-Olam International, Revive Therapeutics Ltd |
|
US |
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-03-27 |
| A medical records based study for the diagnosis and prognosis prediction AI model of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
Shanghai Changzheng Hospital, Wuhan Hankou Hospital |
|
China |
2020-02-01 |
2023-02-28 |
ChiCTR2000030992 |
Phase Not Applicable |
Recruiting |
1 |
37 Months |
1000 |
Fan Li, Tang Hao |
2020-03-30 |
| A clinical trial to evaluate Xifaxan (rifaximin) in combination with established therapies, supportive care and other investigative therapies for the treatment of the symptoms of gastrointestinal distress and pulmonary compromise associated with COVID-19 infection |
Coronavirus disease 19 infection, Gastrointestinal disease, Lung disease |
other therapies alone, rifaximin alone, supportive care treatment alone |
RNA polymerase inhibitor |
|
Salix Pharmaceuticals Inc |
|
US |
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-03-30 |
| A Medical Records Based Study for SARS-COV-2 RNA Level in Blood and Excrement of Novel Coronavirus Pneumonia (COVID-19) Convalescent Patients |
Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia |
|
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The 2nd People's Hospital of Ningbo |
|
China |
2020-03-19 |
2020-09-19 |
ChiCTR2000031014 |
Phase Not Applicable |
Not yet recruiting |
1 |
6 Months |
100 |
Rengbin Ji |
2020-03-31 |
| Favipiravir Combined With Tocilizumab in the Treatment of novel coronavirus pneumonia (COVID-19) - A Multicenter, Randomized, Controlled Trial |
Coronavirus disease 19 infection, Viral pneumonia |
favipiravir plus tocilizumab |
RNA polymerase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Peking University First Hospital |
|
China |
2020-03-01 |
2020-05-01 |
ChiCTR2000030894 |
Phase 4 Clinical |
Recruiting |
10 |
2 Months |
150 |
Guiqiang Wang, Hong Zhao |
2020-03-30 |
| B-DT-COV2: Biomarkers for Identification of SARS-COV-2 Infection |
Coronavirus disease 19 infection, SARS coronavirus infection |
|
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Universita' Degli Studi "Magna Graecia" Di Catanzaro |
Azienda Ospedaliera Policlinico "Mater Domini", Azienda Ospedaliera Pugliese Ciaccio |
Italy |
2020-03-24 |
2020-08-30 |
B-DT-COV2, COVID-19 BIOMARKERS, NCT04322513 |
Phase Not Applicable |
Recruiting |
1 |
5 Months |
110 |
LUCA GALLELLI, Luca Gallelli, |
2020-03-30 |
| EELV and TPP in Covid-19: Prospective, observational study to evaluate transpulmonary pressure, end expiratory lung volume and intraabdominal pressure in mechanical ventilated patients with Covid-19 |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
KKH BergstrasseAbteilung Anästhesie/Intensivmedizin |
|
Germany |
2020-03-26 |
|
DRKS00021186, EELV and TPP in Covid-19, S-579/2016 |
Phase Not Applicable |
Recruiting |
1 |
|
45 |
Armin Kalenka |
2020-03-30 |
| Internet based solution focused brief therapy treating adolescent anxiety under the novel coronavirus pneumonia (COVID-19) outbreak: a randomized controlled trial |
Coronavirus disease 19 infection, Viral pneumonia |
internet based solution focused brief therapy alone |
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Beijing Normal University |
|
China |
2020-04-03 |
2020-08-08 |
ChiCTR2000030989 |
Phase Not Applicable |
Not yet recruiting |
1 |
4 Months |
76 |
Shitao Chen |
2020-03-30 |
| Treatment of Moderate to Severe Coronavirus Disease (COVID-19) in Hospitalized Patients |
Coronavirus disease 19 infection, SARS coronavirus infection |
baricitinib alone, hydroxychloroquine sulfate alone, lopinavir + ritonavir alone, sarilumab alone |
HIV protease inhibitor, IL-6 receptor antagonist, Jak1 tyrosine kinase inhibitor, Jak2 tyrosine kinase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Nova Scotia Health Authority |
Dalhousie University |
Canada |
2020-03-31 |
2021-07-31 |
NCT04321993, SAIL-004 |
Phase 2 Clinical |
Not yet recruiting |
1 |
16 Months |
1000 |
Barbara Goodall, Lisa Barrett |
2020-03-30 |
| Perioperative immune prediction and intervention of tumor patients undergoing surgery during the novel coronavirus pneumonia (COVID-19) outbreak period |
Coronavirus disease 19 infection, Viral pneumonia |
thymosin therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Hunan Cancer Hospital |
|
China |
2020-03-16 |
2020-05-16 |
ChiCTR2000031023, ChiMCTR2000003138 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
320 |
Yang Jinfeng |
2020-03-30 |
| Remedy of human coronavirus infection with genetic nanocomposit drug |
Coronavirus disease 19 infection, Viral pneumonia |
genetical nanocomposit drug (RNA Biotechnology) alone |
|
|
RNA biotechnology |
|
Iran |
2020-03-22 |
|
IR.IAU.KHUISF.REC.1399.001, IRCT20200321046828N1 |
Phase 1/Phase 2 Clinical |
No longer recruiting |
1 |
|
30 |
Dr Mahdi Khozaei, Mr Eng Montazeri, ِDr Mahdi Khozaei |
2020-03-31 |
| A Study to Assess the Effect of ChAdOx1 nCoV-19 in The Prevention Of Coronavirus disease 19 infection |
Coronavirus disease 19 infection |
ChAdOx1 nCoV-19 alone |
|
|
University of Oxford |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-03-27 |
| Use of Ascorbic Acid in Patients With COVID-19 |
Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia |
conventional therapy alone, vitamin C alone |
|
|
University of Palermo |
|
Italy |
2020-03-13 |
2021-03-13 |
3143, NCT04323514 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
500 |
Salvatore Corrao, Salvatore Corrao, MD |
2020-03-30 |
| Colchicine Efficacy in COVID-19 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
colchicine alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Azienda Ospedaliero-Universitaria di Parma |
|
Italy |
2020-04-01 |
2020-06-30 |
COLCOVID01, NCT04322565 |
Phase 2 Clinical |
Not yet recruiting |
1 |
3 Months |
100 |
Lucio Manenti, MD, Umberto Maggiore, MD |
2020-03-30 |
| A clinical trial of opaganib (Yeliva) alone and in combination with other compounds, for the treatment of COVID-19 |
Coronavirus disease 19 infection |
opaganib alone |
Dihydroceramide delta 4 desaturase inhibitor, Sphingosine kinase 2 inhibitor |
|
RedHill Biopharma Ltd |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-03-27 |
| An expanded access protocol to study potential benefit of nebulized treatment with Ampion in patients with SARS-Cov-2 (COVID-19) induced Acute Respiratory Distress Syndrome (ARDS) |
Coronavirus disease 19 infection, Respiratory distress syndrome |
Ampion (intranasal, inflammation), Ampio/DMI Biosciences alone |
Stem cell antigen-1 inhibitor |
|
Ampio Pharmaceuticals Inc |
|
US |
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-03-30 |
| Coalition-I: Safety and Efficacy of Hydroxychloroquine Associated With Azithromycin in SARS-Cov-2 Virus |
Coronavirus disease 19 infection |
hydroxychloroquine alone, azithromycin plus hydroxychloroquine |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital do Coracao |
Brazilian Research In Intensive Care Network, EMS SA, Hospital Of Syrian Lebanese Itatiba S/C Ltd, Sociedade Beneficente Israelita Brasileira Hospital Albert Einsten |
Brazil |
2020-04-06 |
2020-08-30 |
BRAZIL COVID COALITION I TRIAL, Coalition-I, NCT04322123 |
Phase 3 Clinical |
Not yet recruiting |
33 |
4 Months |
630 |
Alexandre Biasi, PhD, Antônio Paulo Nassar, Cassia Righy, Cintia Grion, Cristina Amendola, Emerson Silva, Eraldo Lucio, Felipe Dal Pizzol, Fernando Ramos, Fernando Zampieri, PhD, Flavia Machado, Flávio Freitas, Fábio Lacerda, Glauco Westphal, Hugo Urbano, Israel Maia, Israel Maia, PhD, Jorge Luiz Paranhos, José Andrade Neto, João Manoel Silva Junior, Luciazo Azevedo, Luiz Dalfior Junior, Lúcio Oliveira Junior, Marco Antonio Guedes, Miqueias Silva, Neymar Oliveira, Niklas Soderberg, Otavio Berwanger, Rodrigo Biondi, Rodrigo Cruvinel, Thiago Lisboa, Viviane Veiga, Wilson José Lovato, PhD |
2020-03-30 |
| A clinical study to assess antiviral activity of Elpida in the treatment of patients with COVID-19 |
Coronavirus disease 19 infection |
elsulfavirine alone |
HIV-1 reverse transcriptase inhibitor, Non-nucleoside reverse transcriptase inhibitor |
|
Viriom Inc |
Ministry of Health and Social Development of the Russian Federation, The Chinese Centre for Disease Control and Prevention |
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-03-27 |
| Efficacy of Natural Honey Treatment in Patients With Novel Coronavirus |
Coronavirus disease 19 infection |
standard care alone, Variable regimens including Arbidol , azithromycin , chloroquine , hydroxychloroquine , lopinavir + ritonavir , natural honey , oseltamivir |
Exo-alpha sialidase inhibitor, HIV protease inhibitor |
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Misr University for Science and Technology |
|
Egypt |
2020-03-25 |
2020-05-10 |
MUST23032020, NCT04323345 |
Phase 3 Clinical |
Not yet recruiting |
1 |
1 Month |
1000 |
Mahmoud Ahmed Tantawy, Mahmoud Tantawy, MD |
2020-03-30 |
| A clinical study to assess CoV-2 mRNA vaccine for the potential treatment of SARS-CoV-2 (2019-nCoV) |
Coronavirus disease 19 infection |
cross-strain mRNA vaccine (TriMix/intranasal, coronavirus infection), eTheRNA/EpiVax/ReproCELL alone |
CD40 ligand receptor agonist, CD70 antigen modulator, TLR-4 agonist |
|
eTheRNA immunotherapies NV |
EpiVax Inc, Nexelis, ReproCELL Inc, University of Antwerp |
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-03-31 |
| MP-C19: Efficacy of Methylprednisolone for Patients With COVID-19 Severe Acute Respiratory Syndrome |
Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia |
ECMO alone, antiviral therapy alone, empiric antibiotic therapy alone, mechanical ventilation alone, oxygen therapy alone, standard care alone, vitamins alone, chloroquine plus methylprednisolone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
L'Universita Degli Studi di Trieste |
|
Italy |
2020-03-23 |
2020-05-30 |
MP-19 023_2020, MP-C19, NCT04323592 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
2 Months |
104 |
Francesco Salton, MD, Francesco confalonieri, MD, Marco Confalonieri, MD, marco confalonieri, MD |
2020-03-30 |
| Evaluation the Efficacy and Safety of Tocilizumab in COVID-19 |
Coronavirus disease 19 infection |
Variable regimens including hydroxychloroquine , lopinavir + ritonavir , oseltamivir , tocilizumab (intravenous), Roche/Chugai |
Exo-alpha sialidase inhibitor, HIV protease inhibitor, IL-6 receptor antagonist, IL-6 receptor modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shaheed Beheshti Medical University |
|
Iran |
2020-03-11 |
|
IR.SBMU.NRITLD.REC.1399.002, IRCT20151227025726N13 |
Phase 2 Clinical |
Recruiting |
1 |
|
40 |
Ali Saffaei, Farzaneh Dastan, Payam Tabarsi |
2020-03-30 |
| SOLIDARITY: Public health emergency SOLIDARITY trial of treatments for COVID-19 infection in hospitalized patients |
Coronavirus disease 19 infection, SARS coronavirus infection |
chloroquine alone, hydroxychloroquine alone, lopinavir + ritonavir alone, remdesivir alone, standard of care alone, interferon-beta plus lopinavir + ritonavir |
HIV protease inhibitor, RNA polymerase modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
World Health Organization |
|
Qatar, Norway, South Africa, Canada, Thailand, Spain, Brazil, Argentina, Switzerland, Indonesia, Peru, Germany, Iran |
2020-03-01 |
2021-03-25 |
0003361, ISRCTN83971151, SOLIDARITY |
Phase 3 Clinical |
Recruiting |
13 |
12 Months |
|
Dr MariaHenaoRestrepo, Dr Moorthy, Dr Preziosi |
2020-03-30 |
| ProPAC-COVID: Proactive Prophylaxis With Azithromycin and Chloroquine in Hospitalized Patients With COVID-19 |
Coronavirus disease 19 infection |
standard care alone, azithromycin plus hydroxychloroquine |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Chronic Obstructive Pulmonary Disease Trial Network |
|
|
2020-04-01 |
2021-03-31 |
KRONLUNGESYG_COVID_19_PROTOKOL, NCT04322396, ProPAC-COVID |
Phase 4 Clinical |
Not yet recruiting |
0 |
12 Months |
226 |
Jens-Ulrik Stæhr Jensen, MD, PhD |
2020-03-30 |
| CloroCOVID19: Chloroquine Diphosphate for the Treatment of Severe Acute Respiratory Syndrome Secondary to SARS-CoV2 |
Coronavirus disease 19 infection, SARS coronavirus infection |
chloroquine diphosphate alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Foundation of Tropical Medicine Doctor Heitor Vieira Dourado |
|
Brazil |
2020-03-23 |
2020-08-31 |
CAAE: 30152620.1.0000.0005, CloroCOVID19, NCT04323527 |
Phase 2b Clinical |
Recruiting |
1 |
5 Months |
440 |
Fernando Val, PhD, Marcus Lacerda, PhD, Mayla Borba, MD |
2020-03-31 |
| ONSCOVID19: Anti-inflammatory/Antioxidant Oral Nutrition Supplementation in COVID-19 |
Coronavirus disease 19 infection |
Oxepa alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
King Saud University |
|
Saudi Arabia |
2020-04-01 |
2020-10-30 |
NCT04323228, ONSCOVID19, ONS_COVID-19 |
Phase 4 Clinical |
Not yet recruiting |
1 |
6 Months |
30 |
Mahmoud Abulmeaty, Mahmoud M.A. Abulmeaty, M.D., FACN |
2020-03-30 |
| A clinical trial of Assurance AB COVID-19 IgM/IgG Rapid Antibody Test to detect the presence of IgM and/or IgG antibodies to the SARS-CoV-2 virus |
Coronavirus disease 19 infection, SARS coronavirus infection |
Assurance AB alone |
|
|
Predictive Technology Group Inc |
|
US |
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
|
|
2020-03-30 |
| Study of the metformin effect on the survival and recovery rate of COVID-19 patients |
Coronavirus disease 19 infection |
metformin hydrochloride alone, standard therapy alone |
AMP activated protein kinase stimulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tabriz University of Medical Sciences |
|
Iran |
2020-03-20 |
|
IR.TBZMED.REC.1398.1309, IRCT20160310026998N10 |
Phase 3 Clinical |
Recruiting |
1 |
|
200 |
Ghaffary, Saba Ghaffary, saba ghaffary |
2020-03-30 |
| A phase III, large-scale clinical trial to evaluate the effectiveness of VPM-1002 against an infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in elderly people and healthcare workers |
Coronavirus disease 19 infection, SARS coronavirus infection |
VPM-1002 alone |
Listeriolysin stimulator |
|
Max-Planck Gesellschaft zur Förderung Der Wissenschaften eV |
|
Germany |
|
|
|
Phase 3 Clinical |
Planned |
1 |
|
|
|
2020-03-27 |
| A Phase I/II clinical trial of human monoclonal antibody for potential treatment of SARS-CoV-2 (COVID-19) |
Coronavirus disease 19 infection, SARS coronavirus infection |
human mAbs (COVID-19/ SARS/ MERS), Vir Biotechnology/ NIAID alone |
|
|
Vir Biotechnology Inc |
|
|
|
|
|
Phase 1/Phase 2 Clinical |
Planned |
0 |
|
|
|
2020-03-27 |
| Clinical study of human NK cells and MSCs transplantation for severe novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
SNCP treatment alone, natural killer (NK) cells plus umbilical cord derived mesenchymal stem cells (UC-MSCs) |
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Jiangxi Chest Hospital, Jiangxi Mayo Biotechnologies Co LTD, Second Hospital Affiliated to Nanchang University |
Science and Technology Agency of Jiangxi province |
China |
2020-03-01 |
2020-08-31 |
ChiCTR2000030944 |
Phase 1 Clinical |
Not yet recruiting |
2 |
6 Months |
20 |
Duan Zhongxin, Ye Xiaoqun |
2020-03-30 |
| Venous thrombosis risk of novel coronavirus pneumonia (COVID-19) patients: A prospective study |
Coronavirus disease 19 infection, Phlebothrombosis, Viral pneumonia |
|
|
|
Shandong Provincial Hospital |
|
China |
2020-03-25 |
2020-05-31 |
ChiCTR2000030943 |
Phase Not Applicable |
Not yet recruiting |
1 |
2 Months |
200 |
Jiang Shujuan, Wei Yuanhui |
2020-03-30 |
| Acute Encephalopathy in Critically Ill Patients With SARS-Cov-2 Infection |
Brain disease, Coronavirus disease 19 infection, SARS coronavirus infection |
clinical examination alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ictal Group |
|
France |
2020-03-23 |
2020-12-31 |
NCT04320472, NEURO-COVID-19 |
Phase Not Applicable |
Recruiting |
1 |
9 Months |
250 |
Stephane LEGRIEL, MD, PhD |
2020-03-30 |
| Risk Factors for Community- and Workplace Transmission of COVID-19 |
Coronavirus disease 19 infection |
biological sampling alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Oslo University Hospital |
Age Labs AS |
Norway |
2020-03-28 |
2030-03-20 |
NCT04320732, REK-124170 |
Phase Not Applicable |
Not yet recruiting |
1 |
119 Months |
50000 |
Arne Soraas, MD, PhD, Arne Vasli Lund Soraas, John Arne Dahl, PhD |
2020-03-30 |
| The Efficacy of Different Anti-viral Drugs in (Severe Acute Respiratory Syndrome-Corona Virus-2) SARS-CoV-2 |
Coronavirus disease 19 infection |
hydroxychloroquine alone, remdesivir alone, standard of care alone, hydroxychloroquine plus remdesivir |
RNA polymerase modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Oslo University Hospital |
|
Norway |
2020-03-26 |
2020-11-30 |
118684, NCT04321616 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
2 |
8 Months |
700 |
Andreas Barratt-Due, MD, PhD, Anne Margarita Dyrhol Riise, MD, Professor, Inge Christoffer Olsen, PhD, Katerina Nezvalova-Henriksen, Pharm D, PhD, Marius Troseid, MD, PhD, Paul Aukrust, MD, Professor, Trine Kasine, MD |
2020-03-27 |
| Non-contact Endoscopy at Covid-19 Outbreak |
Coronavirus disease 19 infection |
magnetically-controlled capsule endoscopy (MCE) system (Ankon Technologies) alone, non-contact endoscopy alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Changhai Hospital |
|
China |
2020-03-16 |
2020-03-16 |
NCMCE1, NCT04320953 |
Phase Not Applicable |
Completed |
1 |
|
1 |
Zhuan Liao, MD |
2020-03-27 |
| A medical records based study for clinical features and prognosis of severe patients with novel coronavirus pneumonia (COVID-19) in Huanggan, Hubei in Huanggang |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
Hunan Provincial People's Hospital |
|
China |
2020-03-15 |
2020-12-15 |
ChiCTR2000030941 |
Phase Not Applicable |
Recruiting |
1 |
9 Months |
200 |
Yi-Yin Chen |
2020-03-27 |
| Metabolic abnormalities and rearrangement reversal treatment in COVID-19 infection |
Coronavirus disease 19 infection, Viral pneumonia |
compound amino acid treatment alone, routine treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
The Third Affiliated Hospital of Sun Yat-Sen University |
|
China |
2020-04-01 |
2020-04-01 |
ChiCTR2000031271 |
Phase 1 Clinical |
Not yet recruiting |
1 |
|
80 |
Zhuang-Gui Chen |
2020-03-27 |
| A RCT for Hua-Shi Bai-Du granules in patients with novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Hua-Shi Bai-Du granules alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Guangdong Provincial Hospital of Chinese Medicine |
|
China |
2020-03-20 |
2020-05-31 |
ChiCTR2000030988, ChiMCTR2000003142 |
Phase Not Applicable |
Not yet recruiting |
1 |
2 Months |
204 |
Jianwen Guo, Zhongde Zhang |
2020-03-27 |
| CORIPREV-LR: COVID-19 Ring-based Prevention Trial With Lopinavir/Ritonavir |
Coronavirus disease 19 infection |
lopinavir + ritonavir alone |
HIV protease inhibitor |
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
St Michaels Hospital |
|
Canada |
2020-03-30 |
2022-03-31 |
CORIPREV-1, CORIPREV-LR, NCT04321174 |
Phase 3 Clinical |
Not yet recruiting |
3 |
24 Months |
1220 |
Adrienne Chan, MD MPH FRCPC, Alex Schnubb, Attia Qamar, BEng, Darrell Tan, MD FRCPC PhD |
2020-03-27 |
| A Randomized Controlled Trial for Favipiravir Tablets Combine With Chloroquine Phosphate in the Treatment of Novel Coronavirus Pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
favipiravir alone, chloroquine phosphate plus favipiravir |
RNA polymerase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Beijing Chao-Yang Hospital |
|
China |
2020-03-05 |
2020-06-25 |
ChiCTR2000030987 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
3 Months |
150 |
Shumin Wang, Zhaohui Tong |
2020-03-27 |
| Study for 'Bai-Du Duan Fang' application on the acupoint in the treatment of general type novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Bai-Du Duan Fang application alone, Western medicine alone, acupoint application (Zusanli + Feishu) alone, routine nursing alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Longhua Hospital Shanghai University of TCM |
|
China |
2020-02-01 |
2020-06-30 |
ChiCTR2000030940, ChiMCTR2000003152 |
Phase Not Applicable |
Not yet recruiting |
1 |
5 Months |
76 |
Wei Lu |
2020-03-27 |
| Preliminary evaluation of the safety and efficacy of oral LL-37 antiviral peptide (CAS-001) in the treatment of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
CAS-001 alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Chinese PLA General Hospital |
|
China |
2020-03-16 |
2020-10-01 |
ChiCTR2000030939 |
Phase 0 Clinical |
Recruiting |
2 |
6 Months |
10 |
Gang Sun |
2020-03-27 |
| Correlation of T-lymphocytes level and clinical severity in novel coronavirus pneumonia (COVID-19) patients: a medical records based retrospective study |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The Third People’s Hospital of Shenzhen |
|
China |
2020-03-20 |
|
ChiCTR2000030986 |
Phase Not Applicable |
Recruiting |
1 |
|
200 |
GAO Hong, WU Qiang |
2020-03-27 |
| CamoCO-19: The Impact of Camostat Mesilate on COVID-19 Infection |
Coronavirus disease 19 infection |
camostat mesylate alone |
Serine protease inhibitor, Trypsin inhibitor |
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Aarhus University |
|
Denmark |
2020-03-31 |
2021-05-01 |
2020-001200-42, CamoCO-19, NCT04321096 |
Phase 2a Clinical |
Not yet recruiting |
3 |
13 Months |
180 |
Jacob Bodilsen, Lars Ostergaard, Professor, Ole S Soegaard, MD, PhD, Ole S Sogaard, MD PhD, Ole S Søgaard, MD, PhD |
2020-03-27 |
| Clinical investigation and reseach on TCM syndrome of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin Haihe Hospital |
|
China |
2020-02-28 |
2021-06-30 |
ChiCTR2000030938, ChiMCTR2000003151 |
Phase 0 Clinical |
Recruiting |
2 |
16 Months |
160 |
Sun Hongyuan |
2020-03-27 |
| Psychological Responses of Medical Staff during the Metaphase of Novel Coronavirus pneumonia (COVID-19) Outbreak in Hubei, China |
Anxiety disorder, Coronavirus disease 19 infection, Depression, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Asian Ancestry |
Renmin Hospital of Wuhan University |
|
China |
2020-03-04 |
2020-03-09 |
ChiCTR2000030985 |
Phase Not Applicable |
No longer recruiting |
1 |
|
1300 |
Wenqin Song, Zhongyuan Xia |
2020-03-26 |
| A randomized, open-label, controlled trial for Gu-Shen Ding-Chuan-Wan in the treatment of patients with novel coronavirus pneumonia (COVID-19) at recovery phase with Fei-Pi-Qi-Xu Zhen |
Coronavirus disease 19 infection, Viral pneumonia |
Gu-Shen Ding-Chuan-Wan alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The First Affiliated Hospital of Guangzhou Medical College |
Guangzhou Baiyunshan Jingxiutang Pharmaceutical Co Ltd |
China |
2020-03-19 |
2020-08-30 |
ChiCTR2000030937, ChiMCTR2000003150 |
Phase 4 Clinical |
Recruiting |
6 |
5 Months |
144 |
Li Shi-yue, Zeng Li-jie |
2020-03-30 |
| A real-world study for the Chinese medicines 'Xinguan 2' and 'Xinguan 3' in the treatment of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
regular treatment alone, Jingfanghuopujiedu Mixture (Xinguan No. 3) plus Yinqiaohuopu Tuire Mixture (Xinguan No. 2) |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
The Affiliated Hospital of Chengdu University of Traditional Chinese Medicine |
|
China |
2020-03-10 |
2020-05-10 |
ChiCTR2000030936 |
Phase 3 Clinical |
Recruiting |
15 |
2 Months |
2840 |
Peiyang Gao, Xiaolan Kong |
2020-03-27 |
| A medical records based study for clinical application of extracorporeal membrane oxygenation in the treatment of severe respiratory failure patients with novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Beijing Chao-Yang Hospital, Capital Medical University |
|
China |
2020-02-01 |
2020-04-30 |
ChiCTR2000030947 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
34 |
Xuyan Li, Zhaohui Tong |
2020-03-27 |
| Study for the impact on fetus and neonates of vertical transmission of 2019-nCoV |
Coronavirus disease 19 infection |
|
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Union Hospital Tongji Medical School Huazhong University Of Science & Technology |
Huazhong University of Science and Technology |
China |
2020-02-01 |
2020-08-31 |
ChiCTR2000031140 |
Phase 0 Clinical |
Recruiting |
1 |
7 Months |
300 |
CHEN Hui |
2020-03-27 |
| A Platform for Rapid Immuno-detection and Emergency Vaccine Development of Novel Coronavirus (2019-COV) |
Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia |
|
|
|
Fifth Affiliated Hospital, Sun Yat-Sen University |
|
China |
2020-03-01 |
2021-02-28 |
ChiCTR2000030934 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
90 |
Tian Lin |
2020-03-27 |
| Safety and Effectiveness of Human embryonic stem cell-derived M cells (CAStem) for Pulmonary Fibrosis Correlated with novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Pulmonary fibrosis, Viral pneumonia |
Human embryonic stem cell-derived M cells (CAStem) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Chinese Academy of Sciences, Wuhan Jinyintan Hospital |
Ministry of Science and Technology of the People´s Republic of China |
China |
2020-03-20 |
2021-03-19 |
ChiCTR2000031139 |
Phase 0 Clinical |
Recruiting |
1 |
12 Months |
20 |
Liu Ying, Zhang Dingyu |
2020-03-27 |
| Alliance Covid-19 Brasil II: Safety and Efficacy of Hydroxychloroquine Associated With Azithromycin in SARS-CoV2 Virus |
Coronavirus disease 19 infection |
azithromycin plus hydroxychloroquine |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sociedade Beneficente Israelita Brasileira Hospital Albert Einsten |
Brazilian Research In Intensive Care Network, EMS SA, Hospital Of Syrian Lebanese Itatiba S/C Ltd, Hospital do Coracao |
Brazil |
2020-03-23 |
2020-08-30 |
ALLIANCE COVID-19 BRASIL II, Alliance Covid-19 Brasil II, CAAE, NCT04321278 |
Phase 3 Clinical |
Not yet recruiting |
22 |
5 Months |
440 |
ARO-HIAE Academic Research Organization HIAE, Adrian PM Kormann, MD, Ary Serpa-Neto, PhD, Carla MG Godoy, MD, Cintia MC Grion, MD, Cláudio Galvão, PhD, Cristina P Amendola, MD, Eraldo A Lucio, MD, Fabio H Lacerda, MD, Felipe Dal Pizzol, MD, Fernado G Zampieri, MD, Fernando C Neuenschwander, MD, Fernando G Zampieri, MD, Flavia R Machado, MD, Frederico TC DallOrto, MD, Guilherme Schettino, PhD, Henrique Fonseca, PhD, Israel S Maia, MD, Jorge LR Paranhos, MD, Leonardo R Ferraz, PhD, Luciano CP Azevedo, MD, Luiz V Rizzo, PhD, Marco AV Guedes, MD, Maria SM Paiva, MD, Mauro E Hernandes, MD, Otávio Berwanger, PhD, Remo Furtado, PhD, Rodrigo C Figueiredo, MD, Rodrigo S Biondi, MD, Thiago Correa, PhD, Viviane C Veiga, MD, Wilson J Lovato, MD, Ótávio Berwanger, PhD |
2020-03-27 |
| Psychological Support for Diagnosed Patients with novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
cognitive behavioral therapy alone, psychological support alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Ningbo Kangning Hospital |
|
China |
2020-03-24 |
2022-03-23 |
ChiCTR2000031090 |
Phase Not Applicable |
Not yet recruiting |
1 |
24 Months |
60 |
Haihang Yu, Xiaoli Liu |
2020-03-27 |
| A prognosis study of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Xiangyang First People's Hospital |
|
China |
2020-02-09 |
2022-02-09 |
ChiCTR2000031088 |
Phase Not Applicable |
Recruiting |
1 |
24 Months |
314 |
Huang Guoxin, Pei Bin |
2020-03-27 |
| Prospective exploratory clinical research on the efficacy and safety of pirfenidone capsules in the treatment of severe novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
pirfenidone alone |
PDGF receptor antagonist, TGF beta receptor antagonist, p38 MAP kinase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The Third Xiangya Hospital of Central South University |
|
China |
2020-03-01 |
2020-12-31 |
ChiCTR2000031138 |
Phase 0 Clinical |
Recruiting |
2 |
10 Months |
40 |
Meng Jie |
2020-03-27 |
| Efficacy and safety of aerosol inhalation of vMIP in the treatment of novel coronavirus pneumonia (COVID-19): a single-arm clinical trial |
Coronavirus disease 19 infection, Viral pneumonia |
conventional standardized treatment alone, vMIP alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Union Hospital Tongji Medical School Huazhong University Of Science & Technology |
Guangzhou Suyuan Biotechnology |
China |
2020-02-07 |
2020-07-30 |
ChiCTR2000029636 |
Phase 0 Clinical |
Recruiting |
1 |
5 Months |
40 |
Hu bo, Kuang fa-hao, Li wei, Sun han-xiao |
2020-03-27 |
| Effectiveness of 'Liu-Zi-Jue' combined with respiratory muscle training for respiratory function in novel coronavirus pneumonia (COVID-19) patients: a randomized, controlled trial |
Coronavirus disease 19 infection, Viral pneumonia |
Liu-Zi-Jue exercise alone, respiratory muscle training alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Jiangxi University of Science and Technology, The First Affiliated Hospital of Nanchang University |
|
China |
2020-02-29 |
2020-12-31 |
ChiCTR2000030933 |
Phase 0 Clinical |
Not yet recruiting |
3 |
10 Months |
108 |
Feng Zhen, Li Moyi |
2020-03-27 |
| Correlation between virological negative conversion and clinical factors and prognosis in patients with novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Anqing Municipal Hospital |
|
China |
2020-02-01 |
2020-06-30 |
ChiCTR2000030932 |
Phase Not Applicable |
Recruiting |
1 |
5 Months |
100 |
Changqing Hu, Changtai Wang |
2020-03-27 |
| Psychosocial Effects Of Coronavirus Disease 2019 (COVID-19) Amongst Healthcare Providers In Johor |
Coronavirus disease 19 infection, Psychiatric disorder |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Permai |
|
Malaysia |
2020-02-17 |
2020-08-31 |
53218, NMRR-20-213-53218 |
Phase Not Applicable |
Recruiting |
5 |
6 Months |
|
Dr NURUL NADIA BINTI HASBOLLAH, Suhaila Mohd Som |
2020-03-27 |
| A Medical Records Based Study for Clinical Characteristic and Outcomes of Hospitalized Patients With Novel Coronavirus Pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
Huizhou Municipal Central Hospital, Guangdong |
|
China |
2020-03-23 |
2020-05-22 |
ChiCTR2000030931 |
Phase Not Applicable |
Not yet recruiting |
1 |
2 Months |
60 |
Huang Hui |
2020-03-27 |
| COVID-19 detection by VOC: Early Detection of Novel Coronavirus Pneumonia (COVID-19) Based on a Novel High-Throughput Mass Spectrometry Analysis With Exhaled Breath |
Coronavirus disease 19 infection, Viral pneumonia |
Mass Spectrometry Analysis alone |
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shenzhen Burui Biotechnology Co., Ltd, The Third People’s Hospital of Shenzhen |
|
China |
2020-03-01 |
2023-03-31 |
COVID-19 detection by VOC, ChiCTR2000029695, NCP-VOC |
Phase 0 Clinical |
Not yet recruiting |
1 |
37 Months |
|
Deng Guofang, Fu Liang |
2020-03-27 |
| A Multicenter, Randomized, Parallel Controlled Clinical Study of Hydrogen-Oxygen Nebulizer to Improve the Symptoms of Patients With Novel Coronavirus Pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
hydrogen-oxygen nebulize alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The First Affiliated Hospital of Guangzhou Medical College |
Shanghai Asclepius Meditec Co., Ltd |
China |
2020-02-01 |
2021-08-31 |
ChiCTR2000029739 |
Phase Not Applicable |
Recruiting |
3 |
19 Months |
440 |
Changsheng Zhao, Nanshan Zhong, Zeguang Zheng |
2020-03-27 |
| Risks of Death and Severe cases in Patients with 2019 Novel Coronavirus Pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
Tongji Hospital |
National Natural Science Foundation of China |
China |
2020-01-26 |
2020-03-31 |
ChiCTR2000029735 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
500 |
Min Xie, Xiaochen Li |
2020-03-27 |
| BEAT19: Behavior, Environment And Treatments for COVID-19 |
Coronavirus disease 19 infection, SARS coronavirus infection |
daily diary survey alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
xCures inc |
Cancer Commons, Genetic Alliance, LunaPBC |
US |
2020-03-21 |
2022-03-20 |
BEAT19, NCT04321811, XC-PCOR-COVID19 |
Phase Not Applicable |
Recruiting |
0 |
24 Months |
100000 |
Mark Shapiro, xCures |
2020-03-27 |
| A Medical Records Based Study for the Effectiveness of Extracorporeal Membrane Oxygenation in Patients with Severe Novel Coronavirus Pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
extracorporeal membrane oxygenation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Zhangnan Hospital |
|
China |
2020-01-11 |
2020-12-28 |
ChiCTR2000029949 |
Phase Not Applicable |
Not yet recruiting |
1 |
11 Months |
40 |
Xian-Long, Zhou, Yan, Zhao |
2020-03-30 |
| Impact of vitamin D deficiency on prognosis of patients with novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia, Vitamin D deficiency |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
West China Hospital |
Science & Technology Department of Sichuan Province |
China |
2020-02-10 |
2020-04-10 |
ChiCTR2000029732 |
Phase 0 Clinical |
Not yet recruiting |
4 |
2 Months |
156 |
Jun Guo |
2020-03-27 |
| A randomized, double-blind, parallel-controlled trial to evaluate the efficacy and safety of anti-SARS-CoV-2 virus inactivated plasma in the treatment of severe novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
anti-SARS-CoV-2 virus inactivated plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Renmin Hospital of Wuhan University, Sinopharm Wuhan Blood Products Co., Ltd. |
|
China |
2020-03-17 |
2020-06-16 |
ChiCTR2000030929 |
Phase 2 Clinical |
Not yet recruiting |
1 |
3 Months |
60 |
Binghong Zhang, Lianghao Zhang |
2020-03-27 |
| A phase I clinical trial of COVID-HIG for potential treatment and prevention of coronavirus disease (COVID-19) |
Coronavirus disease 19 infection |
COVID-HIG alone |
|
|
Emergent BioSolutions Inc |
|
|
2020-09-30 |
|
|
Phase 1 Clinical |
Planned |
0 |
|
|
|
2020-03-26 |
| A multicenter study for efficacy of intelligent psychosomatic adjustment system intervention in the treatment of novel coronavirus pneumonia (COVID-19) patients with mild to moderate anxiety and depression |
Anxiety disorder, Coronavirus disease 19 infection, Depression, Viral pneumonia |
intelligent psychosomatic adjustment system intervention therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
The First Hospital of Shanxi Medical University |
|
China |
2020-02-01 |
2022-02-01 |
ChiCTR2000030084 |
Phase 0 Clinical |
Recruiting |
4 |
24 Months |
180 |
Liu Zhifen, Xu Yong |
2020-03-27 |
| Clinical study for the diagnostic value of pulmonary ultrasound for novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
Union Hospital Tongji Medical School Huazhong University Of Science & Technology |
National Natural Science Foundation of China |
China |
2020-02-12 |
2023-02-12 |
ChiCTR2000030087 |
Phase 0 Clinical |
Recruiting |
1 |
36 Months |
800 |
Li Zhang, Mingxing Xie |
2020-03-27 |
| A single-arm study for evaluation of integrated traditional Chinese and western medicine in the treatment of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
TCM syndrome differentiation treatment alone, Western medicine treatment alone |
|
|
Henan University of Chinese Medicine |
|
China |
2020-02-01 |
2020-12-31 |
ChiCTR2000029436, ChiMCTR2000002952 |
Phase 0 Clinical |
Not yet recruiting |
5 |
11 Months |
|
Li Jiansheng, Li Suyun, Xie Yang |
2020-03-27 |
| A Prospective, Randomized, Controlled Trial for Home Exercise Prescription Intervention During Epidemic of Novel Coronary Pneumonia (COVID-19) in College Students |
Coronavirus disease 19 infection, Viral pneumonia |
exercise prescription therapy alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
West China Hospital |
|
China |
2020-02-22 |
2020-03-22 |
ChiCTR2000030090 |
Phase Not Applicable |
Not yet recruiting |
1 |
1 Month |
400 |
LIU YAN, XIONG YAN |
2020-03-27 |
| Cancelled due to lack of patient Medical records based study for epidemiological and clinical characteristics of 2019 novel coronavirus pneumonia (COVID-19) in Chongqing |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Chongqing Three Gorges Central Hospital |
|
China |
2020-02-17 |
|
2020CDJYGRH-YJ03, ChiCTR2000029952 |
Phase Not Applicable |
No longer recruiting |
1 |
|
|
Kaihu Xiao |
2020-03-26 |
| A prospective, randomized, controlled trial for the home exercise prescription intervention in nursing students during epidemic of novel coronary pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
exercise prescription therapy alone |
|
|
West China Hospital |
|
China |
2020-02-22 |
2020-03-22 |
ChiCTR2000030091 |
Phase Not Applicable |
Not yet recruiting |
1 |
1 Month |
200 |
LIU YAN, XIONG YAN |
2020-03-26 |
| Evaluation of myocardial injury of novel coronavirus pneumonia (COVID-19) assessed by multimodal MRI imaging |
Coronavirus disease 19 infection, Viral pneumonia |
multimodal MRI imaging alone |
|
|
West China Second University Hospital |
|
China |
2020-03-01 |
|
ChiCTR2000029955 |
Phase 0 Clinical |
Not yet recruiting |
1 |
|
100 |
Ying-kun Guo |
2020-03-30 |
| Assessment of cardiac function in patients with Novel Coronavirus Pneumonia (COVID-19) by echocardiography and its new techniques |
Coronavirus disease 19 infection, Heart disease, Viral pneumonia |
|
|
|
Union Hospital Tongji Medical School Huazhong University Of Science & Technology |
National Natural Science Foundation of China |
China |
2020-02-12 |
2022-02-12 |
ChiCTR2000030092 |
Phase 0 Clinical |
Recruiting |
1 |
24 Months |
800 |
Li Zhang, Mingxing Xie |
2020-03-30 |
| Pandemic Response Network |
Coronavirus disease 19 infection |
|
|
|
Duke University |
|
US |
2020-03-31 |
2021-12-31 |
NCT04320862, PRO00105189 |
Phase Not Applicable |
Not yet recruiting |
0 |
21 Months |
20000 |
Becky Smith, MD, Mark Sendak, MD, MPP |
2020-03-30 |
| COVACTA: A Study to Evaluate the Safety and Efficacy of Tocilizumab in Patients With Severe COVID-19 Pneumonia |
Coronavirus disease 19 infection |
standard of care alone, tocilizumab (intravenous), Roche/Chugai alone |
IL-6 receptor antagonist, IL-6 receptor modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Genentech Inc, Roche Holding AG |
Biomedical Advanced Research and Development Authority (BARDA) |
US |
2020-03-19 |
2021-09-30 |
2020-001154-22, COVACTA, NCT04320615, WA42380 |
Phase 3 Clinical |
Recruiting |
0 |
18 Months |
330 |
Clinical Trials |
2020-03-31 |
| COVIP: Outcomes and Prognostic Factors in COVID-19 |
Coronavirus disease 19 infection, SARS coronavirus infection |
|
|
Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Heinrich Heine Universitat Dusseldorf |
|
Germany |
2020-03-19 |
2020-12-31 |
20-004, COVIP, NCT04321265 |
Phase Not Applicable |
Recruiting |
1 |
9 Months |
4000 |
Christian Jung, MD, Christian Jung, MD, PhD, Dr. Dr. Christian Jung, Rabea Wagstaff, MA, Raphael Bruno, MD |
2020-03-28 |
| A Pre-exposure, prophylaxis, randomized, placebo-controlled trial in front line health care workers including emergency room staff and ICU staff for the prevention of COVID-19 |
Coronavirus disease 19 infection |
hydroxychloroquine, Apotex Inc alone |
|
|
The University Health Network, Unity Health Toronto |
Apotex Inc |
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
|
|
2020-03-30 |
| A single-arm study for combination of traditional Chinese and Western Medicine in the treatment of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
traditional Chinese and Western Medicine alone |
|
|
Hubei Provincial Department of Education |
|
China |
2020-02-01 |
2020-12-01 |
ChiCTR2000029437, ChiMCTR2000002953 |
Phase Not Applicable |
Not yet recruiting |
1 |
10 Months |
300 |
Xia Wenguang, An Changqing, Zhang Boli, Zhang Junhua |
2020-03-27 |
| Study for application of simplified cognitive-behavioral therapy for related emergency psychological stress reaction of medical providers working in the position of treatment and control of novel coronavirus pneumonia (COVID-19) |
Acute stress disorder, Coronavirus disease 19 infection, Viral pneumonia |
simplify cognitive behavior therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
The Second Hospital of Shanxi Medical University |
|
China |
2020-02-01 |
2021-03-31 |
ChiCTR2000030093 |
Phase Not Applicable |
Not yet recruiting |
1 |
14 Months |
60 |
Tian Feng |
2020-03-27 |
| Beaumont Quantitative Lung Function Imaging to Characterize Patients With SARS-COV 2 |
Coronavirus disease 19 infection, SARS coronavirus infection |
computerized tomography alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
William Beaumont Hospitals |
|
US |
2020-03-23 |
2022-03-31 |
2020-087, NCT04320511 |
Phase Not Applicable |
Recruiting |
0 |
24 Months |
25 |
Girish B Nair, MD, Joanne Gondert, RN, BSN |
2020-03-26 |
| A randomized controlled trial of integrated TCM and Western Medicine in the treatment of severe novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
TCM standard decoction therapy alone, basic western medical therapy alone |
|
|
Beijing Hospital of Traditional Chinese Medicine affiliated to Capital Medical University |
|
China |
2020-02-01 |
2021-12-31 |
ChiCTR2000029438, ChiMCTR2000002954 |
Phase 0 Clinical |
Not yet recruiting |
2 |
23 Months |
120 |
WANG YUGUANG, LI XUCHENG, ZHANG BOLI, ZHANG JUNHUA |
2020-03-27 |
| Clinical study for the integration of traditional Chinese and western medicine in the treatment of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Western medicine basic treatment alone, traditional Chinese medicine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shanghai Pulmonary Hospital |
Tongji University |
China |
2020-02-17 |
2020-10-31 |
ChiCTR2000029790, ChiMCTR2000003009 |
Phase Not Applicable |
Recruiting |
1 |
8 Months |
120 |
Lixin Wang |
2020-03-30 |
| Clinical study of a novel high sensitivity nucleic acid assay for novel coronavirus pneumonia (COVID-19) based on CRISPR-cas protein |
Coronavirus disease 19 infection, Viral pneumonia |
RT-PCR test alone |
|
|
Shenzhen Second People's Hospital |
|
China |
2020-02-16 |
2020-03-20 |
ChiCTR2000029810 |
Phase Not Applicable |
Recruiting |
1 |
1 Month |
1300 |
Weiren Huang |
2020-03-27 |
| Combination of traditional Chinese medicine and western medicine in the treatment of common type novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
TCM standard decoction therapy alone, basic western medical therapy alone |
|
|
Beijing Hospital of Traditional Chinese Medicine affiliated to Capital Medical University |
|
China |
2020-02-01 |
2021-12-31 |
ChiCTR2000029439, ChiMCTR2000002955 |
Phase 0 Clinical |
Not yet recruiting |
2 |
23 Months |
120 |
WANG YUGUANG, LI XUCHENG, ZHANG BOLI, ZHANG JUNHUA |
2020-03-27 |
| A multicenter, randomized, open and controlled trial for the efficacy and safety of Kang-Bing-Du granules in the treatment of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Kangbingdu granules alone, routine treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Union Hospital Tongji Medical School Huazhong University Of Science & Technology |
Sichuan Guangda Pharmacy Co., Ltd. |
China |
2020-02-10 |
2020-06-30 |
ChiCTR2000029781, ChiMCTR2000003005 |
Phase 4 Clinical |
Recruiting |
5 |
4 Months |
160 |
Hong Sun, Xin Zheng |
2020-03-30 |
| Cancelled by the investigator Clinical Study for Anti-aging Active Freeze-dried Powder Granules in the Treatment of Acute Novel Coronavirus Pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Anti-aging Active Freeze-dried Powder Granules alone, Conventional treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Guangzhou reborn health management consultancy co., LTD |
|
China |
2020-02-20 |
2021-02-20 |
ChiCTR2000029811 |
Phase 0 Clinical |
Not yet recruiting |
1 |
12 Months |
60 |
Chao Xu |
2020-03-27 |
| A Medical Records Based Study for Construction and Analysis of Diagnosis Predictive Model of Novel Coronavirus Pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Chongqing Liangjiang New Area first people's Hospital, Dianjiang County People's Hospital of Chongqing |
|
China |
2020-02-21 |
2020-08-21 |
ChiCTR2000030042 |
Phase Not Applicable |
Recruiting |
2 |
6 Months |
240 |
Chen Hao |
2020-03-27 |
| Study for clinical characteristics and distribution of TCM syndrome of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Henan University of Chinese Medicine |
|
China |
2020-02-01 |
2020-12-31 |
ChiCTR2000029462, ChiMCTR2000002960 |
Phase Not Applicable |
Not yet recruiting |
8 |
11 Months |
200 |
Li Jiansheng, Xie Yang |
2020-03-27 |
| Clinical study for the changes in mental state of medical staff in the department of radiotherapy in a comprehensive tertiary hospital in Zhejiang Province during the epidemic of novel coronavirus infection (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Zhejiang Provincial People's Hospital |
|
China |
2020-01-30 |
2020-02-29 |
ChiCTR2000029782 |
Phase Not Applicable |
Not yet recruiting |
1 |
1 Month |
27 |
Tao Song, Yongshi Jia |
2020-03-27 |
| Comparative study for integrate Chinese and conventional medicine the the treatment of novel coronavirus pneumonia (COVID-19) in Hu'nan province |
Coronavirus disease 19 infection, Viral pneumonia |
integrated Chinese and conventional medicine alone |
|
|
The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine |
Hunan Provincial Science and Technology Department |
China |
2020-02-21 |
2020-05-31 |
ChiCTR2000029960 |
Phase 0 Clinical |
Not yet recruiting |
1 |
3 Months |
100 |
CAI Huzhi, CHEN Xinyu |
2020-03-27 |
| Clinical Trial for Integrated Chinese and Western Medicine in the Treatment of Children with Novel Coronavirus Pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Integrated Traditional Chinese alone, Western Medicine alone |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Children's Hospital of Fudan University |
|
China |
2020-02-14 |
2020-12-31 |
ChiCTR2000029814, ChiMCTR2000003013 |
Phase 0 Clinical |
Recruiting |
1 |
10 Months |
30 |
Cao Di, Zhai Xiaowen |
2020-03-27 |
| A medical records based study for the clinical characteristics of anesthesia novel coronavirus pneumonia (COVID-19) patients during perioperative period and assessment of infection and mental health of Anesthesiology Department |
Anesthesia, Anxiety disorder, Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Zhangnan Hospital |
|
China |
2020-01-01 |
|
ChiCTR2000029958 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
260 |
Yingying Chen, Zongze Zhang |
2020-03-27 |
| Application of imaging in the prevention and control system of major respiratory infectious diseases |
Coronavirus disease 19 infection, Lung infection, Viral pneumonia |
imaging alone |
|
|
The 2nd People's Hospital of Ningbo |
|
China |
2020-03-01 |
2020-12-31 |
ChiCTR2000031150 |
Phase Not Applicable |
Recruiting |
1 |
10 Months |
150 |
Jiaying Xu, Jie Lin |
2020-03-27 |
| Investigating effect of convalescent plasma on COVID-19 patients outcome: a randomized Clinical Trial |
Coronavirus disease 19 infection |
convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Sari University of Medical Sciences |
|
Iran |
2020-03-28 |
|
IR.MAZUMS.REC.1399.7330, IRCT20181104041551N1 |
Phase 2 Clinical |
Recruiting |
1 |
|
30 |
Fatemeh Heidari, Professor Majid Saeedi |
2020-03-31 |
| Traditional Chinese medicine cooperative therapy for patients with novel coronavirus pneumonia (COVID-19): a randomized controlled trial |
Coronavirus disease 19 infection, Viral pneumonia |
TCM syndrome differentiation treatment alone, Western medicine conventional chemotherapy regimen alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Dongzhimen Hospital |
|
China |
2020-03-31 |
2020-12-30 |
ChiCTR2000029788, ChiMCTR2000003007 |
Phase Not Applicable |
Not yet recruiting |
1 |
9 Months |
60 |
Jianwei Shang, Xudong Yu, Yaosheng Zhang |
2020-03-27 |
| Chinese Medicine Promotes Rehabilitation Recommendations after 2019 Novel Coronavirus Infection (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
guixi regulating lung gong method alone, health guidance alone, moxibustion treatment alone, shenling baizhu powder alone |
|
|
The Affiliated Hospital of Chengdu University of Traditional Chinese Medicine |
Science & Technology Department of Sichuan Province |
China |
2020-02-18 |
2020-07-01 |
ChiCTR2000029956 |
Phase Not Applicable |
Not yet recruiting |
1 |
4 Months |
120 |
Tang Jianyuan, Tang Shiyun |
2020-03-27 |
| REUSED: A randomized controlled trial for the Efficacy of Ultra Short Wave Electrotherapy in the treatment of Novel Coronavirus Pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Ultra short wave electrotherapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Tongji Hospital, Huazhong University of Science and Technology |
|
China |
2020-02-17 |
2020-05-17 |
ChiCTR2000029972, REUSED |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
40 |
Chen Hong, Huang Liangjiang |
2020-03-27 |
| The relationship between Vitamin D and novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia, Vitamin D deficiency |
|
|
Male, Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
People’s Hospital of Guangxi Zhuang Autonomous Region |
|
China |
2020-02-16 |
2022-02-09 |
ChiCTR2000031163 |
Phase Not Applicable |
No longer recruiting |
1 |
23 Months |
80 |
Kun Ye, Xin Liao |
2020-03-27 |
| Auscultatation of Covid-19: Auscultatory characteristics of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Wireless Stemoscope alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shanghai First People's Hospital |
Shanghai Jiao Tong University |
China |
2020-03-09 |
2020-06-30 |
Auscultatation of Covid-19, ChiCTR2000030722 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
30 |
Zhi Zhang |
2020-03-27 |
| Study for the physical and mental health status of medical workers under the novel coronavirus pneumonia (COVID-19) epidemic |
Anxiety disorder, Coronavirus disease 19 infection, Depression |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
The first affiliated hospital of Guangzhou university of Traditional Chinese medicine, Traditional Chinese Medicine Hospital of Hainan Province Affiliated to Guangzhou University of Chinese Medicine, University of Chinese Academy of Sciences Shenzhen Hospital |
|
China |
2020-03-20 |
2020-04-30 |
ChiCTR2000030850 |
Phase Not Applicable |
Not yet recruiting |
3 |
1 Month |
226 |
Fengbin Liu, Jinglin Pan |
2020-03-27 |
| A medical records based study for Tou-Jie-Qu-Wen Granules in the Treatment of mild and moderate patients with novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Toujiequwen Granules alone, basic treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Guangzhou 8th People's Hospital |
|
China |
2020-03-13 |
2020-04-30 |
ChiCTR2000031089, ChiMCTR2000003144 |
Phase Not Applicable |
Not yet recruiting |
3 |
1 Month |
300 |
Huijun Mao, Luping Lin |
2020-03-30 |
| Research for Traditional Chinese Medicine Technology Prevention and Control of Novel Coronavirus Pneumonia (COVID-19) in the Community Population |
Coronavirus disease 19 infection, Viral pneumonia |
Huoxiangzhengqi oral liquid alone, Jinhao Artemisia Antipyretic granules alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The Affiliated Hospital of Chengdu University of Traditional Chinese Medicine |
|
China |
2020-01-31 |
2020-05-01 |
ChiCTR2000029479, ChiMCTR2000002961 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
20000 |
Tang Jianyuan, Tang Shiyun |
2020-03-27 |
| Traditional Chinese Medicine, Psychological Intervention and Investigation of Mental Health for Patients With Novel Coronavirus Pneumonia (COVID-19) in Convalescent Period |
Coronavirus disease 19 infection, Psychiatric disorder, Viral pneumonia |
Traditional Chinese Medicine alone, psychological intervention alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Hubei Xinhua Hospital, Renmin Hospital of Wuhan University |
|
China |
2020-02-03 |
2021-12-31 |
ChiCTR2000029495 |
Phase 0 Clinical |
Not yet recruiting |
2 |
22 Months |
90 |
Min Huang, Zhengliang Li |
2020-03-27 |
| Chinese medicine prevention and treatment program for suspected novel coronavirus pneumonia (COVID-19): a perspective, double-blind, placebo, randomized controlled trial |
Coronavirus disease 19 infection, Viral pneumonia |
Chinese medicine alone, mechanical ventilation alone, transnasal high-flow oxygen therapy alone, alpha-interferon plus lopinavir + ritonavir |
HIV protease inhibitor |
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Zhejiang Chinese Medical University |
|
China |
2020-02-04 |
2020-04-30 |
ChiCTR2000029517, ChiMCTR2000002963 |
Phase 0 Clinical |
Recruiting |
1 |
2 Months |
100 |
Chengping Wen, Zhijun Xie |
2020-03-27 |
| A Medical Based Retrospective Real World Study for Assessment of Effectiveness of Comprehensive Traditional Chinese Medicine in the treatment of Novel Coronavirus Pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Chinese medicine alone, Western medicine alone |
|
|
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Shanghai University of Traditional Chinese Medicine |
|
China |
2020-02-21 |
2020-12-31 |
ChiCTR2000030163, ChiMCTR2000003047 |
Phase Not Applicable |
Not yet recruiting |
1 |
10 Months |
256 |
Bin Li, Ruiping Wang |
2020-03-30 |
| A cross-sectional study of novel coronavirus pneumonia (COVID-19) patients in ICU |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
Union Hospital Tongji Medical School Huazhong University Of Science & Technology, Wuhan Jinyintan Hospital |
|
China |
|
|
ChiCTR2000030164 |
Phase not specified |
Not yet recruiting |
2 |
|
10 |
You Shang, Yuan Yu |
2020-03-30 |
| Clinical study for ozonated autohemotherapy in the treatment of Novel Coronavirus Pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
conventional treatment alone, ozonated autohemotherapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tianjin University |
|
China |
2020-02-22 |
2020-12-31 |
ChiCTR2000030165 |
Phase Not Applicable |
Recruiting |
1 |
10 Months |
60 |
Ni Guangjian, Yu Hongzhi |
2020-03-31 |
| Chinese medicine prevention and treatment program for novel coronavirus pneumonia (COVID-19): a perspective, double-blind, placebo, randomized controlled trial |
Coronavirus disease 19 infection, Viral pneumonia |
Chinese medicine alone, Western medicine alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Zhejiang Chinese Medical University |
|
China |
2020-02-04 |
2020-04-30 |
ChiCTR2000029518, ChiMCTR2000002964 |
Phase 0 Clinical |
Recruiting |
1 |
2 Months |
140 |
Wen Chengping, Xie Zhijun |
2020-03-27 |
| Feature of Multiple Organs in Ultrasound Investigation for Clinical Management and Prognostic Evaluation of Novel Coronavirus Pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
invasive ultrasound test alone |
|
|
Renmin Hospital of Wuhan University |
National Natural Science Foundation of China |
China |
2020-02-17 |
2020-12-31 |
ChiCTR2000030017 |
Phase Not Applicable |
Recruiting |
1 |
10 Months |
200 |
Bo Hu, Qing Zhou |
2020-03-27 |
| Hydroxychloroquine Post-Exposure Prophylaxis for Coronavirus Disease (COVID-19) |
Coronavirus disease 19 infection |
hydroxychloroquine sulfate (LIPIN1 disease/rhabdomyolysis), INSERM alone |
TLR-9 antagonist |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Columbia University |
|
US |
2020-03-31 |
2022-03-31 |
AAAS9676, NCT04318444 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
0 |
24 Months |
1600 |
Elizabeth Oelsner, MD, MPH |
2020-03-27 |
| Study for the clinical characteristics and digestive system damage of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Gastrointestinal disease, SARS coronavirus infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Guangzhou 8th People's Hospital |
|
China |
2020-03-05 |
2021-03-05 |
ChiCTR2000030519 |
Phase 0 Clinical |
Not yet recruiting |
1 |
12 Months |
40 |
Chuo Li, Yuanjing Zhan |
2020-03-27 |
| The COVID-19 Mobile Health Study (CMHS), a large-scale clinical observational registration study using nCapp |
Coronavirus disease 19 infection, Viral pneumonia |
nCapp COVID-19 risk diagnostic modelling alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shanghai Zhongshan Hospital |
|
China |
2020-02-28 |
2020-05-31 |
ChiCTR2000030019 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
600 |
Chunxue Bai, Dawei Yang |
2020-03-27 |
| BCG-CORONA: Reducing health care workers absenteeism in Coronavirus 2019 pandemic nu enhancement of the immune system through vaccination with Bacillus Calmette-Guerin |
Coronavirus disease 19 infection, SARS coronavirus infection |
Bacillus Calmette-Guerin vaccine alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universitair Medisch Centrum Utrecht |
|
Netherlands |
2020-03-17 |
|
2020-000919-69, 73249, BCG-CORONA, U1111-1249-1107 |
Phase 4 Clinical |
Recruiting |
1 |
|
1000 |
Marc J. M. Bonten |
2020-03-27 |
| COVIDSOT: Multicentric Study of Coronavirus Disease 2019 (COVID-2019) in Solid Organ Transplant Recipients |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fundación Pública Andaluza Para La Gestión De La Investigación En Salud De Sevilla |
GESITRA-IC, Spanish Network for Research in Infectious Diseases |
|
2020-03-31 |
2022-04-30 |
COVIDSOT, COVIDSOT, NCT04319172 |
Phase Not Applicable |
Not yet recruiting |
0 |
25 Months |
50 |
Clara Rosso-Fernández, MD-PhD, Elisa Cordero-Matía, MD-PhD |
2020-03-27 |
| Medical records based study for the correlation between Chinese medicine certificate and lung image of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Chinese Academy of Medical Sciences |
|
China |
2020-03-09 |
2021-12-31 |
ChiCTR2000030597, ChiMCTR2000003096 |
Phase Not Applicable |
Not yet recruiting |
1 |
21 Months |
150 |
Miao Qing, Yuan Shasha |
2020-03-27 |
| A medical records based analysis for the clinical characteristics of novel coronavirus pneumonia (COVID-19) in immunocompromised patients |
Coronavirus disease 19 infection, Viral pneumonia |
medical records based analysis alone |
|
|
Tongji Hospital, Huazhong University of Science and Technology |
National Natural Science Foundation of China |
China |
2020-01-20 |
2020-02-29 |
ChiCTR2000030021 |
Phase Not Applicable |
Recruiting |
1 |
1 Month |
10 |
Zhou Min |
2020-03-27 |
| A multicenter, open-label observation study for psychological status and intervention efficacy of doctors, nurses, patients and their families in novel coronavirus pneumonia (COVID-19) designated hospitals |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ningbo First Hospital, Zhejiang University |
|
China |
2020-03-10 |
2021-03-10 |
2017C510010, 2018KY671, 2019KY564, ChiCTR2000030697 |
Phase Not Applicable |
No longer recruiting |
1 |
12 Months |
1500 |
Zhongze Lou |
2020-03-27 |
| A parallel, randomized controlled clinical trial for the efficacy and safety of Pediatric Huatanzhike granules (containing ipecacuanha tincture) in the treatment of mild and moderate novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Pediatric Huatanzhike granules alone, conventional therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
First Affiliated Hospital of Anhui Medical University |
|
China |
2020-02-22 |
2020-05-22 |
ChiCTR2000030022 |
Phase 4 Clinical |
Not yet recruiting |
6 |
3 Months |
100 |
Liangdan Sun, Song Fan |
2020-03-27 |
| Cancelled due to lack of participants Study for the Impact of Novel Coronavirus Pneumonia (COVID-19) to the Health of the elderly People |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Third People's Hospital of Chongqing |
|
China |
2020-02-21 |
2021-02-28 |
ChiCTR2000030222 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
658 |
Bin Zhan, Wenjing Sun |
2020-03-27 |
| Shedding of SARS-CoV-2 in Human Semen and Evaluation of Reproductive Health of Novel Coronavirus Pneumonia (COVID-19) Male Patients |
Coronavirus disease 19 infection, SARS coronavirus infection |
|
|
Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Union Hospital Tongji Medical School Huazhong University Of Science & Technology |
|
China |
2020-03-11 |
2020-06-30 |
ChiCTR2000030716 |
Phase Not Applicable |
Recruiting |
2 |
3 Months |
150 |
HONGGANG LI |
2020-03-27 |
| The treatment status and risk factors related to prognosis of hospitalized patients with novel coronavirus pneumonia (COVID-19) in intensive care unit, Hebei, China: a descriptive study |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
Hebei Provincial Cancer Hospital |
Science and Technology Department of Hebei Province of China |
China |
2020-02-01 |
2020-06-30 |
ChiCTR2000030226 |
Phase Not Applicable |
Recruiting |
5 |
5 Months |
40 |
Yuhong Chen, Zhenjie Hu |
2020-03-30 |
| Social Media Effect on Knowledge Dissemination During COVID-19 Virus Outbreak |
Coronavirus disease 19 infection |
survey alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Assiut University |
|
Egypt |
2020-03-11 |
2020-03-16 |
ASSIUTU-3-2020, NCT04319315 |
Phase Not Applicable |
Recruiting |
1 |
|
400 |
Aliae Hussein, MD, Aliae Mohamed-Hussein |
2020-03-27 |
| ICU healthcare personnel burnout investigation during the fight against novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Zhangnan Hospital |
|
China |
2020-02-01 |
2020-06-01 |
ChiCTR2000030264 |
Phase Not Applicable |
Not yet recruiting |
1 |
4 Months |
1000 |
WANG Jing |
2020-03-27 |
| Correlation between imaging characteristics and laboratory tests of new coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
Xianning Central Hospital |
|
China |
2020-02-26 |
2020-03-31 |
ChiCTR2000030283 |
Phase Not Applicable |
Recruiting |
1 |
1 Month |
100 |
Kaihu Yu, Yi Zheng |
2020-03-27 |
| Application of Regulating Intestinal Flora in the Treatment of Severe Novel Coronavirus Pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Regulating intestinal flora alone, conventional treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
The First Affiliated Hospital of Zhengzhou University |
Science and Technology Department of Henan Province |
China |
2020-02-01 |
2021-02-01 |
ChiCTR2000029849 |
Phase 0 Clinical |
Recruiting |
1 |
12 Months |
60 |
Huaqi Wang |
2020-03-27 |
| Ba-Bao-Dan in the adjuvant therapy of novel coronavirus pneumonia (COVID-19) patients |
Coronavirus disease 19 infection, Viral pneumonia |
Ba-Bao-Dan alone, conventional treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shao Yifu Hospital |
Chinese Government |
China |
2020-02-11 |
2020-08-11 |
ChiCTR2000029819 |
Phase 4 Clinical |
Recruiting |
1 |
6 Months |
80 |
Xu Hangdi, Ying Kejing |
2020-03-26 |
| An observational study on the clinical characteristics, treatment and outcome of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
variety treatments alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ningbo First Hospital |
|
China |
2020-02-10 |
2020-03-31 |
ChiCTR2000029839 |
Phase 4 Clinical |
Recruiting |
1 |
1 Month |
100 |
Chao Cao |
2020-03-27 |
| Efficacy of Traditional Chinese Medicine in the Treatment of Novel Coronavirus Pneumonia (COVID-19): a Randomized Controlled Trial |
Coronavirus disease 19 infection, Viral pneumonia |
general treatment alone, traditional Chinese medicine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
China Academy of Chinese Medical Sciences, Wuhan Jinyintan Hospital |
National Science and Technology Support Plan of the People's Republic of China |
China |
2020-02-27 |
2020-12-31 |
ChiCTR2000030288, ChiMCTR2000003059 |
Phase Not Applicable |
Recruiting |
1 |
10 Months |
204 |
Huang Luqi, Ruan Lianguo, Zhao Chen |
2020-03-27 |
| A randomized, controlled trial for honeysuckle decoction in the treatment of patients with novel coronavirus (COVID-19) infection |
Coronavirus disease 19 infection, Viral pneumonia |
honeysuckle decoction alone |
|
|
Nangjing Second Hospital Affiliated Southeast Medical University, Nanjing University |
|
China |
2020-02-07 |
2020-04-30 |
ChiCTR2000029822 |
Phase 0 Clinical |
Recruiting |
1 |
2 Months |
110 |
Likun Zhou, Yongxiang Yi |
2020-03-26 |
| Medical records based study for heart-type fatty acid-binding protein on prognosis of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
Chongqing Three Gorges Central Hospital |
|
China |
2020-02-15 |
|
ChiCTR2000029829 |
Phase Not Applicable |
Terminated |
1 |
|
40 |
Wang Hailong |
2020-03-27 |
| COVID-19: Effects of Social Isolation From Coronavirus; on Physical Activity, Quality of Life and Stress |
Coronavirus disease 19 infection, Viral pneumonia |
beck depression scale alone, physical activity questionnaire alone, short form 12 quality of life scale alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Istanbul University-Cerrahpasa |
|
Turkey |
2020-03-25 |
2020-07-20 |
COVID-19, EAVCIL, NCT04319211, İPEK YELDAN |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
200 |
Eren Avcıl, M.Sc,Pt, İpek Yeldan, Prof. |
2020-03-26 |
| Clinical observation and research plan of novel coronavirus pneumonia (COVID-19) patients |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shanghai Public Health Clinical Center |
|
China |
2020-03-01 |
2020-05-31 |
ChiCTR2000030293 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
300 |
Feng Li, Haicheng Tang |
2020-03-26 |
| Effects of novel coronavirus pneumonia (COVID-19) on menstruation, TCM body construction and psychological state for female at different ages |
Anxiety disorder, Coronavirus disease 19 infection, Depression, Menstruation disorder, Viral pneumonia |
|
|
Female, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Chengdu University of Traditional Chinese Medicine |
Ministry of Science and Technology of the People´s Republic of China |
China |
2020-03-01 |
2021-02-28 |
ChiCTR2000030094 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
200 |
Hua Lu, Qi Zhang |
2020-03-26 |
| Clinical Trial of Favipiravir Tablets Combine With Chloroquine Phosphate in the Treatment of Novel Coronavirus Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
favipiravir alone, chloroquine phosphate plus favipiravir |
RNA polymerase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Beijing Chao-Yang Hospital |
|
China |
2020-03-05 |
2020-06-25 |
2020-K-24-2, NCT04319900 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
3 Months |
150 |
Lihong Liu, Shumin Wang, Phd. |
2020-03-26 |
| CT Scores Predict Mortality in 2019-nCoV Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
Shanghai First People's Hospital |
|
China |
2020-01-31 |
2020-02-18 |
CT2019-NCOV, NCT04284046 |
Phase Not Applicable |
Completed |
1 |
|
39 |
Ruilan Wang |
2020-03-26 |
| A randomized, open-label, blank-controlled, multicenter trial for Shuang-Huang-Lian oral solution in the treatment of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Lianhua Qingwen alone, Shuanghuanglian alone, routine treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tongji Hospital, Huazhong University of Science and Technology |
HPGC Renmintongtai Pharmaceutical Corporation |
China |
2020-02-05 |
2021-02-05 |
ChiCTR2000029605, ChiMCTR2000002975 |
Phase 4 Clinical |
Recruiting |
2 |
12 Months |
400 |
Liu Cailing, Wang Daowen, Zhao Jianping |
2020-03-26 |
| COVID-BioB: COVID-19 Patients Characterization, Biobank, Treatment Response and Outcome Predictor |
Coronavirus disease 19 infection, SARS coronavirus infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universita Vita-Salute San Raffaele |
|
Italy |
2020-03-19 |
2022-03-19 |
COVID-BIOB/OSR, COVID-BioB, NCT04318366 |
Phase Not Applicable |
Recruiting |
1 |
24 Months |
1000 |
Alberto Zangrillo, Professor, Giovanni Landoni, Giovanni Landoni, Professor |
2020-03-26 |
| SEROCOV: Sars-CoV2 Seroconversion Among Front Line Medical and Paramedical Staff in Emergency, Intensive Care Units and Infectious Disease Departments During the 2020 Epidemic |
Coronavirus disease 19 infection, SARS coronavirus infection |
blood sample alone |
|
Healthy volunteers accepted |
Assistance Publique Hopitaux de Paris |
|
France |
2020-03-16 |
2020-10-16 |
APHP200310, NCT04304690, SEROCOV |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
1000 |
David BOUTOLLEAU, MD, Pierre HAUSFATER, MD PHD |
2020-03-26 |
| Covid-19 ,remdesivir, Tamiflu |
Coronavirus disease 19 infection |
oseltamivir alone, remdesivir alone |
Exo-alpha sialidase inhibitor, RNA polymerase modulator |
|
Hospital Queen Elizabeth |
|
Malaysia |
2020-03-03 |
2020-05-01 |
53302, NMRR-20-347-53302 |
Phase Not Applicable |
Status not specified |
1 |
1 Month |
|
Dr lem fui fui |
2020-03-26 |
| Critically Ill Patients With COVID-19 in Hong Kong: a Multicenter, Observational, Cohort Study |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Chinese University of Hong Kong |
|
Hong Kong |
2020-02-14 |
2020-02-25 |
2020.059, NCT04285801 |
Phase Not Applicable |
Completed |
3 |
|
8 |
Lowell Ling |
2020-03-26 |
| A randomized controlled Trial for therapeutic efficacy of Recombinant Human Interferon alpha 1b Eye Drops in the treatment of elderly with novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
recombinant human interferon alpha 1b alone |
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Chinese PLA General Hospital |
|
China |
2020-02-19 |
2020-05-31 |
ChiCTR2000029989 |
Phase 4 Clinical |
Not yet recruiting |
2 |
3 Months |
300 |
Feng Cao, Yabin Wang |
2020-03-26 |
| Traditional Chinese medicine cooperative therapy for patients with Novel coronavirus pneumonia (COVID-19) and its effect on spermatogenesis: a randomized controlled trial |
Coronavirus disease 19 infection, Viral pneumonia |
Traditional Chinese medicine alone, Western medicine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Dongzhimen Hospital |
|
China |
2020-02-19 |
2021-02-18 |
ChiCTR2000030027 |
Phase Not Applicable |
Recruiting |
3 |
12 Months |
60 |
Chun-yan Ji, Jian-wei Shang, Ting-rong Huang, Xu-dong Yu, Yao-sheng Zhang |
2020-03-26 |
| A clinical study to study COVID-HIG for the potential treatment of COVID-19 |
Coronavirus disease 19 infection |
COVID-HIG alone |
|
|
Emergent BioSolutions Inc |
|
|
2020-09-30 |
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-03-26 |
| A randomized, open and controlled clinical trial for traditional Chinese medicine in the treatment of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Traditional Chinese medicine alone, clear lung prescription alone, compound houttuynia mixture alone, qingfei prescription alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
The First Affiliated Hospital of college of medicine Zhejiang University |
|
China |
2020-02-15 |
|
ChiCTR2000029855 |
Phase Not Applicable |
Recruiting |
1 |
|
180 |
Wu Guolin |
2020-03-27 |
| A randomized controlled trial for the efficacy of Dao-Yin in the prevention and controlling novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Dao Yin alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Shanghai University of Traditional Chinese Medicine |
Shanghai University of Traditional Chinese Medicine |
China |
2020-02-21 |
2020-07-31 |
ChiCTR2000029978, ChiMCTR2000003033 |
Phase 0 Clinical |
Not yet recruiting |
2 |
5 Months |
186 |
Fang Min, Zhang Shuaipan |
2020-03-31 |
| Study for establishment of correlation between virological dynamics and clinical features in novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Peking University First Hospital |
|
China |
2020-02-17 |
2020-08-31 |
ChiCTR2000030096 |
Phase Not Applicable |
Not yet recruiting |
1 |
6 Months |
120 |
Hong Zhao |
2020-03-26 |
| A clinical study to study COVID-EIG for the potential treatment of COVID-19 |
Coronavirus disease 19 infection |
COVID-EIG alone |
|
|
Emergent BioSolutions Inc |
|
|
2020-09-30 |
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-03-26 |
| CODIV-ACE: ACE Inhibitors, Angiotensin II Type-I Receptor Blockers and Severity of COVID-19 |
Coronavirus disease 19 infection |
ACE inhibitors therapy alone, angiotensin receptor-blocker therapy alone, anti-aldosterone agents therapy alone, diuretics therapy alone, Variable regimens including chloroquine , cortisone , lopinavir + ritonavir , remdesivir , sacubitril , tocilizumab , valsartan |
Angiotensin I receptor antagonist, Angiotensin II receptor antagonist, HIV protease inhibitor, RNA polymerase modulator |
|
Neuromed IRCCS |
|
Italy |
2020-03-23 |
2020-04-30 |
CODIV-ACE, DEP-012020, NCT04318418 |
Phase Not Applicable |
Not yet recruiting |
1 |
1 Month |
5000 |
Augusto Di Castelnuovo, Augusto Di Castelnuovo, MSc, PhD, Licia Iacoviello, Licia Iacoviello, MD, PhD |
2020-03-26 |
| Evaluation of Rapid Diagnostic Kit (IgM/IgG) for Novel Coronavirus Pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
nucleic acid detection method alone |
|
|
Jiangsu Institute of Parasitic Diseases, Jiangsu Provincial People’s Hospital |
|
China |
2020-02-15 |
2020-12-31 |
ChiCTR2000029870 |
Phase 0 Clinical |
Recruiting |
3 |
10 Months |
600 |
Cao Jun |
2020-03-26 |
| Experimental Trial of rhIFN-alpha Nasal Drops to Prevent 2019-nCOV in Medical Staff |
Coronavirus disease 19 infection |
recombinant human interferon alpha-1b alone, recombinant human interferon alpha-1b plus thymalfasin |
Thymosin receptor agonist |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Shanghai Jiao Tong University |
|
China |
2020-01-21 |
2020-06-30 |
INTERFERON_PROPHYLAXIS, NCT04320238 |
Phase 3 Clinical |
Recruiting |
1 |
5 Months |
2944 |
Zhongji Meng |
2020-03-26 |
| A randomized, open-label, controlled trial for the safety and efficiency of Kesuting syrup and Keqing capsule in the treatment of mild and moderate novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
conventional therapy alone, Variable regimens including Keqing capsule , Kesuting syrup , conventional therapy |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Guizhou Bailing Group Pharmaceutial Co Ltd, The First Affiliated Hospital of Nanchang University |
|
China |
2020-02-15 |
2020-07-18 |
ChiCTR2000029991, ChiMCTR2000003035 |
Phase 4 Clinical |
Recruiting |
3 |
5 Months |
24 |
Tiantian Sun, Wei Zhang |
2020-03-26 |
| Transmission dynamic of the novel coronavirus in China |
Coronavirus disease 19 infection |
|
|
Asian Ancestry |
Clinical Research Malaysia |
|
Malaysia |
2020-02-10 |
2021-02-21 |
53195, NMRR-20-179-53195, corona01 |
Phase Not Applicable |
Status not specified |
1 |
12 Months |
|
Law Kian Boon |
2020-03-27 |
| CMHS: The COVID-19 Mobile Health Study |
Coronavirus disease 19 infection |
nCapp alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Chinese Alliance against Lung Cancer |
Shanghai Respiratory Research Institute |
China |
2020-02-14 |
2020-05-31 |
CAALC-008-CMHS, CMHS, NCT04275947 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
450 |
Chunlin Dong, Chunxue Bai, Dawei Yang, Jie Liu, Maosong Ye, Xun Wang, Yong Zhang |
2020-03-26 |
| Construction of a bio information platform for novel coronavirus pneumonia (COVID-19) patients follow-up in Anhui |
Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Anhui Provincial Hospital |
Chinese Academy of Sciences |
China |
2020-02-01 |
2022-02-01 |
ChiCTR2000030331 |
Phase Not Applicable |
Recruiting |
1 |
24 Months |
498 |
Weng Jianping, Zheng Xueying |
2020-03-31 |
| Study for using multiomics in the diagnosis and treatment of novel coronavirus pneumonia (COVID-19) |
Bacterial infection, Coronavirus disease 19 infection, Influenza virus infection, Viral pneumonia |
|
|
Healthy volunteers accepted |
Union Hospital Tongji Medical School Huazhong University Of Science & Technology |
|
China |
2020-02-18 |
2020-12-31 |
ChiCTR2000029982 |
Phase 0 Clinical |
Recruiting |
1 |
10 Months |
150 |
Huang Qi, Jin Yang |
2020-03-31 |
| A comparative study on the sensitivity of nasopharyngeal and oropharyngeal swabbing for the detection of SARS-CoV-2 by real-time PCR |
Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia |
gene sequencing alone, real-time RT-PCR alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Huazhong University of Science and Technology, Tongji Hospital, Tongji Medical College |
|
China |
2020-02-15 |
2020-03-31 |
ChiCTR2000029883 |
Phase 0 Clinical |
Not yet recruiting |
1 |
1 Month |
200 |
Xu Shuyun |
2020-03-26 |
| COVID-preg: Clinical Characteristics of Coronavirus Disease 2019 (COVID-19) in Pregnancy |
Coronavirus disease 19 infection |
|
|
Female |
Universita degli Studi di Napoli Federico II |
|
Italy |
2020-01-01 |
2020-05-01 |
06/20, COVID-preg, NCT04319016 |
Phase Not Applicable |
Recruiting |
1 |
4 Months |
20 |
Gabriele Saccone |
2020-03-26 |
| Rapid DNA Amplification assay for COVID-19 |
Coronavirus disease 19 infection |
Rapid Isothermal DNA Amplification assay alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Malaya |
|
Malaysia |
2020-03-16 |
2022-03-15 |
53855, NMRR-20-535-53855 |
Phase Not Applicable |
Not yet recruiting |
2 |
24 Months |
|
Dr Lau Yee Ling, Dr NUR IZATI BINTI MUSTAPA |
2020-03-26 |
| Clinical study of novel NLRP Inflammasome inhibitor (Tranilast) in the treatment of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
conventional therapy alone, tranilast alone |
Histamine H1 receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Anhui Provincial Hospital |
|
China |
2020-02-15 |
2020-07-30 |
ChiCTR2000030002 |
Phase 4 Clinical |
Recruiting |
1 |
5 Months |
30 |
Chengchao Ding, Hongliang He |
2020-03-26 |
| Evaluate the effectiveness of traditional Chinese medicine in the treatment of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
traditional Chinese medicine alone, western medicine alone |
|
|
Affiliated Hospital of Changchun University of Traditional Chinese Medicine |
Jilin Provincial Science & Technology Department |
China |
2020-01-31 |
2020-12-31 |
ChiCTR2000029896 |
Phase Not Applicable |
Recruiting |
1 |
11 Months |
100 |
Shi Li, Wang Tan |
2020-03-26 |
| KP COVID-19: KP COVID-19 |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ministry of Health, Malaysia |
|
Malaysia |
2020-03-23 |
2020-03-27 |
54367, KP COVID-19, NMRR-20-559-54367 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
|
Dr Shubash Shander a/l Ganapathy, Mrs. Komathi Perialathan, PUAN NAZIRAH BINTI ALIAS |
2020-03-27 |
| PFACOVID: PFACOVID |
Coronavirus disease 19 infection, Psychiatric disorder |
online-based psychological intervention alone |
|
|
Universiti Kebangsaan Malaysia Medical Centre |
|
Malaysia |
2020-03-02 |
2021-02-28 |
54410, NMRR-20-584-54410, PFACOVID |
Phase Not Applicable |
Status not specified |
1 |
11 Months |
|
Dr Nik Ruzyanei Nik Jaafar, Dr nur iwana binti abdul taib, Dr. Hajar Bt Mohd Salleh Sahimi |
2020-03-27 |
| Knowledge and Practice of Infection Control among Ministry of Health staffs during COVID-19 Outbreak |
Coronavirus disease 19 infection |
|
|
|
Ministry of Health, Malaysia, National Institutes of Health Malaysia |
|
Malaysia |
2020-03-23 |
2020-04-30 |
NMRR-20-571-54388 |
Phase Not Applicable |
Status not specified |
1 |
1 Month |
|
Dr Halizah Binti Mat Rifin, Mrs. Komathi Perialathan |
2020-03-26 |
| Effect of Novel Coronavirus Pneumonia (COVID-19) on the Mental Health of College Students |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
West China Hospital |
|
China |
2020-02-17 |
2023-01-31 |
ChiCTR2000030004 |
Phase Not Applicable |
Not yet recruiting |
1 |
35 Months |
150000 |
Tao Li, Xiaojing Li |
2020-03-26 |
| SRCOVID-19: SRCOVID-19 |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ministry of Health, Malaysia |
|
Malaysia |
2020-01-04 |
2020-12-31 |
NMRR-20-574-54389, SRCOVID-19 |
Phase Not Applicable |
Not yet recruiting |
1 |
11 Months |
|
Dr LOW LEE LAN |
2020-03-26 |
| Evaluation the Efficacy and Safety of Hydroxychloroquine Sulfate in Comparison with Phosphate Chloroquine in Severe Patients with Novel Coronavirus Pneumonia (COVID-19): a Randomized, Open-Label, Parallel, Controlled Trial |
Coronavirus disease 19 infection, Viral pneumonia |
hydroxychloroquine sulfate alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Peking University Third Hospital |
|
China |
|
|
ChiCTR2000029898 |
Phase 4 Clinical |
Recruiting |
3 |
|
100 |
Shen Ning |
2020-03-26 |
| A medical records based study for acute kidney injury in novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
urine analysis alone |
|
|
Tongji Hospital, Huazhong University of Science and Technology |
National Natural Science Foundation of China |
China |
2020-02-01 |
2020-05-01 |
ChiCTR2000030030 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
2000 |
Gang Xu, Shuwang Ge |
2020-03-26 |
| Nucleic acid analysis of novel coronavirus pneumonia (COVID-19) in morning sputum samples and pharyngeal swabs-a prospectively diagnostic test |
Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tongji Hospital, Huazhong University of Science and Technology |
|
China |
2020-02-21 |
2020-04-21 |
ChiCTR2000030005 |
Phase Not Applicable |
Not yet recruiting |
1 |
2 Months |
|
Cheng Yu, Jingzhi Ma |
2020-03-26 |
| Study on ultrasonographic manifestations of new type of novel coronavirus pneumonia (covid-19) in non-critical stage of pulmonary lesions |
Coronavirus disease 19 infection, Viral pneumonia |
ultrasonography alone |
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Xi'an Chest Hospital |
|
China |
2020-02-10 |
2020-03-28 |
ChiCTR2000030032 |
Phase Not Applicable |
Recruiting |
1 |
1 Month |
20 |
Huang Yi |
2020-03-26 |
| Assessment of Serological Response and Potential Risk Factors for COVID-19 Infection Among Healthcare Workers |
Coronavirus disease 19 infection |
|
|
|
Clinical Research Malaysia |
|
Malaysia |
2020-01-01 |
2020-03-31 |
NMRR-20-575-54382 |
Phase Not Applicable |
Status not specified |
1 |
3 Months |
|
Dr Lee Yee Leng |
2020-03-26 |
| Study for the TCM syndrome characteristics of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Guangdong Provincial Hospital of Chinese Medicine, Hubei Hospital of Integrated Traditional Chinese and Western Medicine Zhongshan Branch, Tianjin University of Traditional Chinese Medicine |
|
China |
2020-02-02 |
2020-12-01 |
ChiCTR2000029430, ChiMCTR2000002947 |
Phase Not Applicable |
Not yet recruiting |
1 |
10 Months |
600 |
ZHANG Boli, ZHANG Zhongde, Zhang Juhana |
2020-03-31 |
| A real world study for Compound Houttuyniae Mixture for prevention of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Compound Houttuynia Mixture alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Lishui People's Hospital, Wenzhou Central Hospital, Yancheng Hospital of TCM affiliated to Nanjing University of Chinese Medicine |
Zhejiang Conba Traditional Medicine Co.,Ltd |
China |
2020-02-29 |
2020-06-30 |
ChiCTR2000030168, ChiMCTR2000003045 |
Phase Not Applicable |
Not yet recruiting |
3 |
4 Months |
2000 |
Dawei Wang, Ruifan Shi |
2020-03-31 |
| Effect evaluation and prognosis of Chinese medicine based on Novel Coronavirus Pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Traditional Chinese Medicine alone |
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The first affiliated Hospital Of Anhui University Of Traditional Chinese Medicine |
Department of Science and Technology of Anhui Province |
China |
2020-02-10 |
2021-02-10 |
ChiCTR2000029747 |
Phase 0 Clinical |
Recruiting |
3 |
12 Months |
200 |
Mei Dong, Nianzhi Zhang |
2020-03-27 |
| COVID: Closed-Loop Oxygen to Verify That Healthcare Workers Interventions Decrease During Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
FreeO2 alone, oxygen alone, usual care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universite Laval |
|
|
2020-04-06 |
2021-10-31 |
2020-3445, 21909, COVID, NCT04320056 |
Phase 2 Clinical |
Not yet recruiting |
0 |
18 Months |
216 |
François Lellouche, Pierre-Alexandre Bouchard |
2020-03-30 |
| Clinical study for the remedy of M1 macrophages target in the treatment of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
M1 suppression therapy alone, methylprednisolone alone, severe intesive treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Affiliated Zhongshan Hospital of Dalian University |
|
China |
2020-01-29 |
2020-12-31 |
ChiCTR2000029431 |
Phase 0 Clinical |
Recruiting |
2 |
11 Months |
45 |
Dewei Zhao, Zhijie Ma |
2020-03-31 |
| Evaluation the Efficacy and Safety of Hydroxychloroquine Sulfate in Comparison with Phosphate Chloroquine in Mild and Commen Patients with Novel Coronavirus Pneumonia (COVID-19): a Randomized, Open-label, Parallel, Controlled Trial |
Coronavirus disease 19 infection, Viral pneumonia |
hydroxychloroquine sulfate alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Peking University Third Hospital |
|
China |
2020-02-17 |
2020-04-30 |
ChiCTR2000029899 |
Phase 4 Clinical |
Recruiting |
3 |
2 Months |
100 |
Shen Ning |
2020-03-26 |
| A randomized, open-label, blank-controlled trial for Lian-Hua Qing-Wen Capsule/Granule in the treatment of suspected novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
lianhua qingwen (oral/capsule, influenza), Yiling Pharmaceutical alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hebei Yiling Hospital, Renmin Hospital of Wuhan University |
Shijiazhuang Yiling Pharmaceutical Co Ltd |
China |
2020-02-01 |
2020-12-01 |
ChiCTR2000029433, ChiMCTR2000002949 |
Phase not specified |
Not yet recruiting |
7 |
10 Months |
240 |
Duan Zhongping, Han Shuolong, Jia Zhenhua, Li Lanjuan, Li Xingwang, Liu Qingquan, Song Yuanlin, Zhang Boli, Zhong Nanshan |
2020-03-31 |
| Convalescent plasma for the treatment of severe and critical novel coronavirus pneumonia (COVID-19): a prospective, randomized, controlled trial |
Coronavirus disease 19 infection, Viral pneumonia |
antibacterial treatment alone, antiviral treatment alone, convalescent plasma alone, symptomatic treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
China-Japan Friendship Hospital, Institute of Blood Transfusion, Chinese Academy of Medical Sciences, Union Hospital Tongji Medical School Huazhong University Of Science & Technology |
|
China |
2020-02-14 |
2021-02-05 |
ChiCTR2000029757 |
Phase 0 Clinical |
Recruiting |
12 |
11 Months |
200 |
Cao Bin, Liu Zhong |
2020-03-27 |
| COVID-19/HSB1: COVID-19/HSB1 |
Coronavirus disease 19 infection |
|
|
|
Hospital Sungai Buloh |
|
Malaysia |
2020-04-01 |
2021-03-31 |
54339, COVID-19/HSB1, NMRR-20-580-54339 |
Phase Not Applicable |
Status not specified |
1 |
12 Months |
|
Dr Mohan Dass Pathmanathan |
2020-03-30 |
| A randomized controlled trial for the efficacy of ozonated autohemotherapy in the treatment of Novel Coronavirus Pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
ozonated autohemotherapy alone |
|
|
Union Hospital Tongji Medical School Huazhong University Of Science & Technology |
|
China |
2020-02-19 |
2020-05-19 |
2018YFC2001802, ChiCTR2000030006 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
30 |
Chen Xiangdong, Han Linlin |
2020-03-26 |
| Research for Risks Associated with Novel Coronavirus Pneumonia (COVID-19) in the Hospital Workers and Nosocomial Prevention and Control Strategy |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Renmin Hospital of Wuhan University |
|
China |
2020-02-17 |
2020-02-29 |
ChiCTR2000029900 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
200 |
Bimuchibu, Yu Jia |
2020-03-26 |
| A medical records based study of novel coronavirus pneumonia (COVID-19) and influenza virus co-infection |
Coronavirus disease 19 infection, Influenza virus infection, SARS coronavirus infection, Viral pneumonia |
|
|
|
Hubei Clinical Research Center, Zhangnan Hospital |
|
China |
2020-02-10 |
2020-03-15 |
ChiCTR2000029905 |
Phase Not Applicable |
Recruiting |
1 |
1 Month |
271 |
Zhao Yan, Zhou Xianlong |
2020-03-26 |
| A study for the intervention of Xiangxue antiviral oral solution and Wu-Zhi-Fang-Guan-Fang on close contacts of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Wu-Zhi-Fang-Guan-Fang decoction alone, Xiangxue antiviral oral solution alone, routine quarantine measures alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The First Affiliated Hospital of Guangzhou Medical College |
|
China |
2020-02-14 |
2020-06-30 |
ChiCTR2000030033 |
Phase Not Applicable |
Not yet recruiting |
1 |
4 Months |
828 |
Feng Wang, Harry H.X. Wang |
2020-03-26 |
| SUNRISE Study: Cohort Study of Novel Coronavirus Pneumonia (COVID-19) Critical Ill Patients |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
West China Hospital |
Science & Technology Department of Sichuan Province |
China |
2020-02-03 |
2022-02-01 |
ChiCTR2000029758, SUNRISE Study |
Phase 0 Clinical |
Recruiting |
1 |
23 Months |
100 |
Cheng Jiangli, Kang Yan |
2020-03-27 |
| A retrospective, cohort study for integrated traditional Chinese and western medicine in the treatment of 1071 patients with novel coronavirus pneumonia (COVID-19) in Wuhan |
Coronavirus disease 19 infection, Viral pneumonia |
routine treatment of western medicine alone, traditional chinese medicine alone |
|
|
Wuhan Integrated Traditional Chinese Medicine & Western Medicine Hospital |
|
China |
2020-03-01 |
2020-12-31 |
ChiCTR2000030719 |
Phase Not Applicable |
Recruiting |
1 |
10 Months |
1071 |
Jia Wen, Wei Li |
2020-03-26 |
| Imaging Features and Mechanisms of Novel Coronavirus Pneumonia (COVID-19): a Multicenter Study |
Coronavirus disease 19 infection, Viral pneumonia |
chest CT scan alone |
|
|
West China Hospital |
|
China |
2020-02-16 |
2020-12-31 |
ChiCTR2000029764 |
Phase 0 Clinical |
Not yet recruiting |
1 |
10 Months |
100 |
Bin Song, Zixing Huang |
2020-03-27 |
| Study for the correlation between the incidence and outcome of novel coronary pneumonia (COVID-2019) and ovarian function in women |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Female |
Tongji Hospital, Huazhong University of Science and Technology |
|
China |
2020-02-19 |
2020-08-19 |
ChiCTR2000030015 |
Phase 0 Clinical |
Recruiting |
1 |
6 Months |
300 |
Jinjin Zhang, Shixuan Wang |
2020-03-31 |
| Babaodan Capsule used for the adjuvant treatment of severe novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Inflammatory disease, Viral pneumonia |
Babaodan alone, Routine treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Taizhou Enze Hospital |
|
China |
2020-02-15 |
2020-04-30 |
ChiCTR2000029769 |
Phase 0 Clinical |
Not yet recruiting |
1 |
2 Months |
40 |
Jiang Yongpo, Lv Dongqing |
2020-03-27 |
| Study for the effect of early endotracheal intubation on the outcome of novel coronavirus pneumonia (COVID-19) patients |
Coronavirus disease 19 infection, Viral pneumonia |
endotracheal intubation alone |
|
|
Union Hospital Tongji Medical School Huazhong University Of Science & Technology |
|
China |
2020-02-23 |
|
ChiCTR2000030056 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Qingping Wu |
2020-03-26 |
| A randomized, open-label, blank-controlled trial for Lian-Hua Qing-Wen capsule/granule in the treatment of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
lianhua qingwen (oral/capsule, influenza), Yiling Pharmaceutical alone, routine treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hebei Yiling Hospital, Renmin Hospital of Wuhan University |
Shijiazhuang Yiling Pharmaceutical Co Ltd |
China |
2020-02-01 |
2020-12-01 |
ChiCTR2000029434, ChiMCTR2000002950 |
Phase 4 Clinical |
Recruiting |
8 |
10 Months |
240 |
Duan Zhongping, Han Shuolong, Jia Zhenhua, Li Lanjuan, Li Xingwang, Liu Qingquan, Song Yuanlin, Zhang Boli, Zhong Nanshan |
2020-03-30 |
| A randomized controlled trial for traditional Chinese medicine in the treatment for novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
traditional Chinese medicine compound granules alone, western medicine symptomatic treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Longhua Hospital Shanghai University of TCM |
Ministry of Science and Technology of the People´s Republic of China, Shanghai Committee of Science and Technology |
China |
2020-03-01 |
2020-06-01 |
ChiCTR2000029941 |
Phase Not Applicable |
Not yet recruiting |
5 |
3 Months |
200 |
Lu Zhenhui, Qiu Lei |
2020-03-26 |
| Study for epidemiology, diagnosis and treatment of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
Union Hospital Tongji Medical School Huazhong University Of Science & Technology |
National Natural Science Foundation of China |
China |
2020-02-13 |
2020-05-31 |
ChiCTR2000029770 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
500 |
Huang Qi, Jin Yang |
2020-03-27 |
| COVILLE: Prevalence of SARS-Cov2 Carriage in Asymptomatic and Mildly-symptomatic Children |
Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia |
PCR alone, nasopharyngeal swabbing alone |
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) |
Centre Hospitalier Intercommunal Creteil |
ACTIV, France |
France |
2020-04-30 |
2020-06-30 |
2020-A00724-35, COVILLE, COVILLE, NCT04318431 |
Phase Not Applicable |
Not yet recruiting |
15 |
2 Months |
600 |
Alain Wollner, Anne-Sylvestre Michot, Annie ELBEZ, Aurélie SELLAM, Camille JUNG, MD, Catherine Turberg-Romain, Christophe BATARD, Elisa SEROR, François Corrard, Gwenaelle D'acremont, Lucette Coicadan, Marc Koskas, Marie-José Bodin, Mohammed Benani, Nadia D'Ovidio, Nassira Belaroussi, Olivier Romain, Patrice Deberdt, Robert Cohen, Sophie RAVILLY, Veronique Derkx |
2020-03-30 |
| Study for the key issues of the diagnosis and treatment of novel coronavirus pneumonia (COVID-19) based on the medical imaging |
Coronavirus disease 19 infection, Pneumonia, Viral pneumonia |
diagnosis model based on artificial intelligence alone |
|
|
Wuxi People's Hospital |
|
China |
2020-02-14 |
2020-05-31 |
ChiCTR2000029779 |
Phase 0 Clinical |
Recruiting |
1 |
3 Months |
|
Xiangming Fang |
2020-03-27 |
| A randomized controlled trial for Qingyi No. 4 compound in the treatment of convalescence patients of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Qingyi No. 4 compound alone, western medicine symptomatic treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Longhua Hospital Shanghai University of TCM |
Ministry of Science and Technology of the People´s Republic of China, Shanghai Committee of Science and Technology |
China |
2020-03-01 |
2020-06-01 |
ChiCTR2000029947 |
Phase Not Applicable |
Not yet recruiting |
5 |
3 Months |
200 |
Lu Zhenhui, Qiu Lei |
2020-03-26 |
| microRNA as a marker for early diagnosis of novel coronavirus infection (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
COVID-19 viral PCR alone |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Second Affiliated Hospital Nanjing Medical University |
|
China |
2020-02-19 |
2020-06-19 |
ChiCTR2000030334 |
Phase 0 Clinical |
Recruiting |
1 |
4 Months |
50 |
Likun Zhou, Yongxiang Yi |
2020-03-27 |
| Research and Development of Diagnostic Assistance Decision Support System for novel coronavirus pneumonia (COVID-19) Based on Big Data Technology |
Coronavirus disease 19 infection, Viral pneumonia |
Diagnostic Assistance Decision Support System alone, chest CT alone |
|
|
Ministry of Information Industry |
|
China |
2020-02-01 |
2020-06-01 |
ChiCTR2000030390 |
Phase Not Applicable |
Recruiting |
18 |
4 Months |
3000 |
Bohan Liu, Kunlun He |
2020-03-27 |
| Experimental study of novel coronavirus pneumonia rehabilitation plasma therapy severe novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
plasma treatment alone, routine treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
The First Affiliated Hospital of Nanchang University |
|
China |
2020-02-24 |
2020-04-24 |
ChiCTR2000030179 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
100 |
Le Aiping, Liu wei |
2020-03-31 |
| Study for the clinical characteristics of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
The Third Xiangya Hospital of Central South University |
National Natural Science Foundation of China |
China |
2020-03-03 |
2020-04-01 |
ChiCTR2000030464 |
Phase Not Applicable |
Recruiting |
1 |
|
200 |
Chengxian Guo |
2020-03-27 |
| JOCOVID: Joint Use of Electrocardiogram and Transthoracic Echocardiography in an Observational Study to Monitor Cardio-vascular Events in Patients Diagnosed With COVID-19 |
Cardiovascular disease, Coronavirus disease 19 infection |
PCR alone, electrocardiogram alone, transthoracic echocardiography alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Groupe Hospitalier Pitie-Salpetriere |
|
France |
2020-03-20 |
2020-05-20 |
CIC1421-20-05, JOCOVID, NCT04320017 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
500 |
Joe Elie Salem, Joe-Elie Salem, MD-PhD |
2020-03-26 |
| BARI-COVID: Baricitinib in Symptomatic Patients Infected by COVID-19: an Open-label, Pilot Study |
Coronavirus disease 19 infection |
baricitinib plus ritonavir |
Cytochrome P450 3A4 inhibitor, HIV protease inhibitor, HIV-1 protease inhibitor, Jak1 tyrosine kinase inhibitor, Jak2 tyrosine kinase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ospedale di Prato |
|
Italy |
2020-03-16 |
2020-04-30 |
BARI-COVID, HPRATO-3, NCT04320277 |
Phase 3 Clinical |
Recruiting |
1 |
1 Month |
60 |
Fabrizio Cantini, Fabrizio Cantini, MD, Laura Niccoli, MD |
2020-03-26 |
| A Pilot Study of Human Amniotic Fluid for COVID19 Associated Respiratory Failure |
Coronavirus disease 19 infection |
human amniotic fluid alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Utah |
|
US |
2020-03-20 |
2021-03-20 |
131618, NCT04319731 |
Phase 0 Clinical |
Not yet recruiting |
0 |
12 Months |
10 |
Craig Selzman, MD, Joseph Tonna, MD |
2020-03-26 |
| Investigation on Mental Health Status and Psychological Intervention of Hospitalized Patients with Novel Coronavirus Pneumonia (COVID-19) |
Coronavirus disease 19 infection, Psychiatric disorder, Viral pneumonia |
Psychological counseling alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Yongchuan Hospital of Chongqing Medical University |
|
China |
2020-02-26 |
2020-09-26 |
ChiCTR2000030466 |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
50 |
Song Ying |
2020-03-27 |
| A Clinical Trial Study for the Influence of TCM Psychotherapy on Negative Emotion of Patients with Novel Coronavirus Pneumonia (COVID-19) Based on Network Platform |
Coronavirus disease 19 infection, Psychiatric disorder, Viral pneumonia |
Integrated Chinese and Conventional medicine treatment alone, TCM psychological intervention alone, conventional medicine's psychological intervention alone |
|
|
Dalian Medical University, China, Lei Shen Shan Hospital |
Science and technology Agency of Liaoning Province |
China |
2020-03-01 |
2020-08-31 |
ChiCTR2000030467 |
Phase Not Applicable |
Not yet recruiting |
1 |
6 Months |
60 |
Wei Yao, Xin Niu |
2020-03-27 |
| A study to assess the effect of S-protein modulator (COVID-19), Celletrion in patient with COVID-19 |
Coronavirus disease 19 infection |
S-protein modulator (COVID-19), Celletrion alone |
Moesin modulator |
|
Celltrion Healthcare Co Ltd |
|
|
2020-09-30 |
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-03-27 |
| Phase II trial of NP-120 (Ifenprodil) for treating COVID-19 |
Coronavirus disease 19 infection |
ifenprodil (injectable, COVID-19/acute lung injury), Nash Pharmaceuticals alone |
NMDA receptor epsilon 2 subunit inhibitor |
|
Algernon Pharmaceuticals |
Novotech (Australia) Pty Ltd |
Australia |
|
|
|
Phase 2 Clinical |
Planned |
1 |
|
|
|
2020-03-27 |
| Phase II trial of NP-120 (Ifenprodil) for COVID-19 |
Coronavirus disease 19 infection |
ifenprodil (injectable, COVID-19/acute lung injury), Nash Pharmaceuticals alone |
NMDA receptor epsilon 2 subunit inhibitor |
|
Algernon Pharmaceuticals |
Novotech (Australia) Pty Ltd |
South Korea |
|
|
|
Phase 2 Clinical |
Planned |
1 |
|
|
|
2020-03-27 |
| COVIDED: ED Response against Covid-19 pandemic |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
INSERM |
|
France |
2020-03-20 |
|
COVIDED, TCTR20200321001 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
5000 |
Enrique Casalino |
2020-03-27 |
| A clinical trial of WP-1122 for treatment of COVID-19 |
Coronavirus disease 19 infection |
WP-1122 alone |
|
|
Moleculin Biotech Inc, University of Texas System |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-03-25 |
| Solidarity trial: A a large global clinical trial to evlauate the efficacy of combination of four drugs remdesivir, lopinavir + ritonavir, interferon beta, and chloroquine for the treatment of COVID-19 |
Coronavirus disease 19 infection, SARS coronavirus infection |
chloraquine alone, lopinavir + ritonavir alone, lopinavir/ritonavir/interferon beta alone, remdesivir alone |
HIV protease inhibitor, RNA polymerase modulator |
|
World Health Organization |
|
France, Thailand, Argentina, Spain, Norway, Switzerland, Canada, Iran, South Africa, Bahrain |
|
|
Solidarity trial |
Phase Not Applicable |
Planned |
10 |
|
|
|
2020-03-24 |
| Awareness Between Pregnant Women Regarding Corona |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Female, Young Adults (18-44 yrs) |
Aljazeera Hospital |
|
Egypt |
2020-03-24 |
2020-05-02 |
NCT04317365, RESPIRATORY INFECTION |
Phase Not Applicable |
Not yet recruiting |
1 |
1 Month |
500 |
Ahmed Elgazzar, M.D, Mahmoud Alalfy, Mahmoud Alalfy, master |
2020-03-24 |
| A Phase I/II clinical trial with CK-0802 for treatment of COVID-19 mediated acute respiratory distress syndrome (CoV-ARDS) |
Coronavirus disease 19 infection, Respiratory distress syndrome |
CK-0802 alone |
|
|
Cellenkos Inc |
Biomedical Advanced Research and Development Authority (BARDA) |
US |
|
|
|
Phase 1/Phase 2 Clinical |
Planned |
0 |
|
|
|
2020-03-24 |
| A clinical trial of astaxanthin for potential treatment of COVID-19 |
Coronavirus disease 19 infection |
astaxanthin alone |
|
|
Cardax Inc |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-03-24 |
| PHYDRA: Hydroxychloroquine Chemoprophylaxis in Healthcare Personnel in Contact With COVID-19 Patients |
Coronavirus disease 19 infection |
hydroxychloroquine sulfate (LIPIN1 disease/rhabdomyolysis), INSERM alone |
TLR-9 antagonist |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Institute of Respiratory Diseases, Mexico |
Sanofi SA |
Mexico |
2020-04-01 |
2021-03-31 |
NCT04318015, PHYDRA, PROFILAXISCOVID |
Phase 3 Clinical |
Not yet recruiting |
1 |
12 Months |
400 |
Alejandra Ramírez-Venegas, MD, MSc, Carmen Hernandez Cárdenas, MD, MSc, Cristobal Guadarrama-Pérez, MD, Felipe Camacho-Jurado, MD, Felipe Jurado-Camacho, MD. MSc, Ireri Thirion-Romero, MD, MSc, Jorge Rojas-Serrano, MD, PhD., Rogelio Perez-Padilla, MD, Rogelio Perez-Padilla, MD. PhD., Sebastian Rodríguez-Llamazares, MD, MPH |
2020-03-25 |
| TBCOVID-19: Biomarkers for prognosis in critically ill COVID-19 patients: a prospective, cohort study |
Coronavirus disease 19 infection |
|
|
|
St. Elisabeth Ziekenhuis |
|
Netherlands |
2020-03-16 |
2020-08-16 |
NL8460, TBCOVID-19 |
Phase Not Applicable |
Recruiting |
1 |
5 Months |
50 |
JAH VAN Oers |
2020-03-25 |
| HT-COVID19: Hypertension in Patients Hospitalized With COVID-19 |
Coronavirus disease 19 infection, Hypertension |
ACEI treatment alone, ARB treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Nanfang Hospital First Medical University of PLA |
|
China |
2020-03-21 |
2020-03-30 |
HT-COVID19, NCT04318301, ZHENHUAZEN2018 |
Phase Not Applicable |
No longer recruiting |
1 |
|
275 |
Zhenhua Zeng |
2020-03-25 |
| A trial to evaluate Rebif for the treatment of patients with COVID-19 |
Coronavirus disease 19 infection |
recombinant interferon beta-1a, Merck Serono alone |
Interferon beta ligand |
|
INSERM |
|
France |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
|
|
2020-03-24 |
| COVID19-HCW: COVID-19: Healthcare Worker Bioresource: Immune Protection and Pathogenesis in SARS-CoV-2 |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University College London |
Royal Free Hospital NHS Foundation Trust, St Bartholomew's Hospital, The University College London Hospitals NHS Trust |
UK |
2020-03-18 |
2021-12-31 |
130852, COVID19-HCW, NCT04318314 |
Phase Not Applicable |
Recruiting |
10 |
21 Months |
400 |
Ben O'Brien, Charlotte Manisty, Gabriella Captur, Hugh Montgomery, James C Moon, James C Moon, MD MBBS MRCP, James Moon, Mahdad Noursadeghi, Steffen Petersen, Thomas Treibel |
2020-03-27 |
| Evaluting The Therapeutic and Adverse Effects of Interferon beta 1-alpha in patients with Novel Coronavirus(COVID-19) |
Coronavirus disease 19 infection |
Variable regimens including hydroxychloroquine , interferon beta-1 alpha , lopinavir + ritonavir , oseltamivir |
Exo-alpha sialidase inhibitor, HIV protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shaheed Beheshti Medical University |
|
Iran |
2020-03-03 |
|
IR.SBMU.NRITLD.REC.1398.102, IRCT20151227025726N12 |
Phase 3 Clinical |
Recruiting |
1 |
|
20 |
Ali Saffaei, Farzaneh Dastan, Payam Tabarsi |
2020-03-25 |
| A clinical trial of Pritumumab for the potential treatment of COVID-19 |
Coronavirus disease 19 infection |
pritumumab alone |
Vimentin modulator |
|
Nascent Biotech Inc |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-03-26 |
| PIENTER Corona: Immunity against SARS-CoV-2 in Dutch population |
Coronavirus disease 19 infection |
|
|
|
National Institute for Public Health and the Environment |
Dutch Ministry of Health, Welfare and Sport |
Netherlands |
2020-03-23 |
2021-09-23 |
IIV-450, NL73474.100.20, NL8473, PIENTER Corona, R20.022 |
Phase Not Applicable |
Not yet recruiting |
1 |
18 Months |
4000 |
Alienke Wijmenga-Monsuur |
2020-03-25 |
| NOSCOVID: The Effect of Noscapine on Clinical and Pulmonary Manifestations of COVID-19 Patients |
Coronavirus disease 19 infection, Lung disease |
noscapine alone |
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Qazvin University Of Medical Sciences |
|
Iran |
2020-03-19 |
2020-04-17 |
IR.QUMS.REC.1398.417, IRCT20160625028622N1, NOSCOVID |
Phase 2 Clinical |
Recruiting |
1 |
|
125 |
Dr Ehsan Aali, Dr Mohammad Ali Zohal, Dr. Imam Friday |
2020-03-25 |
| HOPE: NestCell Mesenchymal Stem Cell to Treat Patients With Severe COVID-19 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
NestCell alone, standard care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Azidus Brasil |
Cellavita Pesquisa Científica Ltda, Hospital Espanol de Veracruz |
|
2020-04-30 |
2020-06-30 |
HOPE, HOPE, NCT04315987 |
Phase 1 Clinical |
Not yet recruiting |
0 |
2 Months |
24 |
Florentino de Araujo Cardoso Filho, Luciana Ferrara |
2020-03-25 |
| Predictors of Respiratory Failure in SARS-Cov-2 Infection |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universita di Bologna |
|
Italy |
2020-03-20 |
2020-05-31 |
NCT04316949, PREDI-CO |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
350 |
Michele Bartoletti, Pierluigi Viale, MD |
2020-03-28 |
| Combination therapy in COVID-19 |
Coronavirus disease 19 infection |
Variable regimens including atazanavir , hydroxychloroquine , lopinavir + ritonavir , ritonavir |
Cytochrome P450 3A4 inhibitor, HIV GAG POL polyprotein inhibitor, HIV GAG protein inhibitor, HIV protease inhibitor, HIV-1 protease inhibitor |
|
Tehran University of Medical Sciences |
|
Iran |
2020-03-15 |
|
IR.TUMS.VCR.REC.1398.1058, IRCT20100228003449N30 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
|
50 |
Hossein Khalili |
2020-03-26 |
| DisCoVeRy: Trial of Treatments for COVID-19 in Hospitalized Adults |
Coronavirus disease 19 infection |
lopinavir + ritonavir alone, remdesivir alone, standard of care alone, Variable regimens including hydroxychloroquine , interferon beta-1a , lopinavir + ritonavir |
HIV protease inhibitor, RNA polymerase modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
INSERM |
French Ministry of Research, Ministry of Health, France |
France, Sweden, Germany, Spain, UK, Benelux, Belgium, Luxembourg, Netherlands |
2020-03-22 |
2023-03-31 |
2020-000936-23, C20-15, DisCoVeRy, NCT04315948 |
Phase 3 Clinical |
Recruiting |
13 |
36 Months |
3100 |
Christelle DELMAS, Florence Ader, MD, François Raffi, François-Xavier Lescure, Hélène Espérou, MD, Jean Reignier, Jean-François Timsit, Julien Poissy, Karine Faure |
2020-03-26 |
| Acute Kidney Injury in Patients Hospitalized With COVID-19 |
Coronavirus disease 19 infection, Renal injury |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Nanfang Hospital First Medical University of PLA |
|
China |
2020-02-26 |
2020-03-08 |
HKYY2020-005 AKI, NCT04316299 |
Phase Not Applicable |
Completed |
1 |
|
287 |
Zhenhua Zen |
2020-03-31 |
| Zedoary Turmeric Oil for Injection in the treatment of Novel Coronavirus Pneumonia (COVID-19): a randomized, open, controlled trial |
Coronavirus disease 19 infection, Viral pneumonia |
zedoary turmeric oil alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The Second Hospital and Yuying Children's Hospital of Wenzhou Medical University |
|
China |
2020-02-29 |
2020-05-31 |
ChiCTR2000030518 |
Phase 0 Clinical |
Recruiting |
1 |
3 Months |
60 |
Lixue Zhang, Yuanrong Dai |
2020-03-24 |
| SAC-COVID: CD24Fc as a Non-antiviral Immunomodulator in COVID-19 Treatment |
Coronavirus disease 19 infection, SARS coronavirus infection |
CD24-IgFc alone |
Signal transducer CD24 modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
OncoImmune Inc |
|
US |
2020-05-31 |
2022-05-31 |
CD24FC-007, NCT04317040, SAC-COVID |
Phase 3 Clinical |
Not yet recruiting |
0 |
24 Months |
230 |
Martin Devenport, PhD, Pan Zheng, MD, PhD, Shyamasundaran Kottilil |
2020-03-24 |
| Clinical Characteristics and Long-term Prognosis of 2019-nCoV Infection in Children |
Coronavirus disease 19 infection |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Beijing Children's Hospital |
Capital Institute of Pediatrics, Children's Hospital Of Hebei Province, Children's Hospital of Changchun, Children's Hospital of Chongqing Medical University, China Medical University (China), China-Japan Friendship Hospital, First Affiliated Hospital of Anhui Medical University, Guangzhou Women and Children's Medical, Hainan People's Hospital, Jiangxi Province Children's Hospital, Kunming Children's Hospital, Nanjing Children's Hospital, Shanxi Provincial Maternity and Children's Hospital, Shenzhen Children's Hospital, The First Affiliated Hospital of Guangxi Medical University, The First Affiliated Hospital of Xiamen University, The Second Hospital and Yuying Children's Hospital of Wenzhou Medical University, Tianjin Childrens Hospital, Tianjin Medical University, Wuhan medical care center for women and children, Xi'an Children's Hospital |
China |
2020-02-15 |
2020-12-31 |
BCH LUNG 012, NCT04270383 |
Phase Not Applicable |
Not yet recruiting |
1 |
10 Months |
500 |
Baoping Xu, MD,PhD, Kunling Shen, MD,PhD, Lina Wang, Tianyou Wang, MD,PhD |
2020-03-24 |
| HYDRA: Hydroxychloroquine Treatment for Severe COVID-19 Pulmonary Infection |
Coronavirus disease 19 infection, Respiratory disease |
hydroxychloroquine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Institute of Respiratory Diseases, Mexico |
Sanofi SA |
Mexico |
2020-03-23 |
2021-03-22 |
HIDROXYCLOROQUINACOVID19, HYDRA, NCT04315896 |
Phase 3 Clinical |
Not yet recruiting |
1 |
12 Months |
500 |
Carmen Hernandez-Cárdenas, MD. MSc, Carmen Hernandez-Cárdenas, MD. MSc., Cristobal Guadarrama, MD MSc, Ireri Thirion-Romero, MD. MSc, Joel Vasquez-Pérez, MD, Luis-Felipe Jurado-Camacho, MD, Rogelio Perez-Padilla, MD. PhD, Rogelio Perez-Padilla, MD. PhD., Sebastian Rodriguez-Llamazares, MD.MPH |
2020-03-24 |
| PRINCIPLE: Can hydroxychloroquine and coronavirus swabbing reduce hospital admission or death for older patients with suspected coronavirus infection? |
Coronavirus disease 19 infection, SARS coronavirus infection |
hydroxychloroquine sulphate alone |
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Oxford |
|
UK |
2020-03-12 |
2021-03-24 |
2020-001209-22, IRAS 281958, ISRCTN86534580, PRINCIPLE |
Phase 3 Clinical |
Not yet recruiting |
2 |
12 Months |
3000 |
Dr Emily Bongard, Dr Emma Ogburn, Dr Sharon Tonner, Mrs Hannah Swayze, Ms Julie Allen, Prof Butler |
2020-03-25 |
| NOSO-COR: Multicenter Study on Nosocomial Transmission of SARS-CoV-2 Virus |
Coronavirus disease 19 infection, SARS coronavirus infection |
nasopharyngeal swab alone, real-time RT-PCR assay alone |
|
|
Hospices Civils De Lyon |
|
France |
2020-03-09 |
2020-10-30 |
69HCL20_0214, NCT04290780, NOSO-COR |
Phase Not Applicable |
Recruiting |
2 |
7 Months |
300 |
Cedric DANANCHE, MD, Hubert Endtz, MD, PhD, PHILIPPE VANHEMS, MD, Philippe VANHEMS, MD, PhD, Philippe VANHEMS, MP,PhD |
2020-03-31 |
| 2019-nCoV Outbreak and Cardiovascular Diseases |
Anxiety disorder, Cardiovascular disease, Coronavirus disease 19 infection |
|
|
|
Qilu Hospital of Shandong University |
|
China |
2020-01-20 |
2020-04-30 |
2019NCOV-CVD, NCT04255940 |
Phase Not Applicable |
Recruiting |
12 |
3 Months |
12000 |
Bin Li, MD, Bin Li, MD, PhD, Bo Li, MD, PhD, Jianjun Lu, MD, Kun Wen, MD, Lei Cao, MD, Liang Shan, MD, Lujing Meng, MD, Min Feng, MD, PhD, Panpan Hao, MD, Panpan Hao, MD, PHD, Peixin Hu, MD, Xin Zhang, MD, Xuexi Hao, MD, Yanping Liu, MD, Zhengyan Qu, MD, Zhongwen Zhang, MD, PHD, kun Wen, MD |
2020-03-26 |
| NO COVID-19: Norwegian Coronavirus Disease 2019 Study |
Coronavirus disease 19 infection, SARS coronavirus infection |
hydroxychloroquine sulfate (LIPIN1 disease/rhabdomyolysis), INSERM alone, standard of care alone |
TLR-9 antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital, Akershus |
|
Norway |
2020-03-23 |
2025-03-03 |
2020-001010-38, Ahus-NO-COVID-19, NCT04316377, NO COVID-19, REC 121446 |
Phase 4 Clinical |
No longer recruiting |
1 |
59 Months |
202 |
Department of Infectious Diseases, Olav Dalgard, MD PhD |
2020-03-24 |
| CCP-nCoV: Clinical Characterization Protocol for Severe Emerging Infections |
Coronavirus disease 19 infection |
|
|
|
INSERM |
|
France |
2020-02-07 |
2023-08-07 |
2020-A00256-33, C20-05, CCP-nCoV, NCT04262921 |
Phase Not Applicable |
Recruiting |
4 |
42 Months |
500 |
Denis MALVY, Eric CAUMES, Hélène ESPEROU, Jean-Francois TIMSIT, Yazdan YAZDANPANAH |
2020-03-24 |
| A clinical trial of hydroxychloroquine for treatment for coronavirus COVID-19 disease |
Coronavirus disease 19 infection |
hydroxychloroquine sulfate (LIPIN1 disease/rhabdomyolysis), INSERM alone |
TLR-9 antagonist |
|
University of Minnesota |
|
US |
|
|
|
Phase 3 Clinical |
Recruiting |
0 |
|
1500 |
David Boulware |
2020-03-23 |
| A trial of an inhaled antiviral drug to treat or prevent severe respiratory difficulties in patients with COVID-19 |
Coronavirus disease 19 infection |
inhaled interferon beta (lung disorders/influenza), Synairgen alone |
Interferon beta ligand |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Synairgen plc |
|
UK |
2020-03-17 |
|
2020-001023-14, SG016 |
Phase 2 Clinical |
Recruiting |
1 |
|
400 |
Jody Brookes |
2020-03-25 |
| Evaluation of the effect of taking Newgen beta-gluten probiotic composite powder to nutrition intervention of patients with novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Newgen beta-gluten probiotic composite powder alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The 2nd People's Hospital of Ningbo |
|
China |
2020-02-01 |
2021-05-01 |
2020YJY0202, ChiCTR2000030897 |
Phase Not Applicable |
Recruiting |
1 |
15 Months |
20 |
Honghua Ye, Ting Cai |
2020-03-24 |
| A phase I clinical study of DPX-COVID-19 for the potential prevention of COVID-19 infection |
Coronavirus disease 19 infection |
DPX-COVID-19 alone |
|
|
IMV Inc |
Canadian Government |
Canada |
|
|
|
Phase 1 Clinical |
Planned |
3 |
|
|
Dr. Gary Kobinger, Joanne Langley, Scott Halperin |
2020-03-24 |
| Clinical Performance of the VivaDiag COVID-19 lgM / IgG Rapid Test in Early Detecting the Infection of COVID-19 |
Coronavirus disease 19 infection |
VivaDiag COVID-19 lgM/IgG Rapid Test kit alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centro Studi Internazionali |
VivaChek Laboratories, Inc |
Italy |
2020-03-31 |
2020-11-30 |
NCT04316728, VIVADIAG-2020 |
Phase Not Applicable |
Not yet recruiting |
1 |
8 Months |
200 |
Antonio V Gaddi, MD, MSc, Fabio V Capello, MD, PhD, Maurizio Cipolla, MD |
2020-03-24 |
| I-COVID: Clinical Characteristics of Coronavirus Disease 2019 (COVID-19) in Pregnancy: The Italian Registry on Coronavirus in Pregnancy |
Coronavirus disease 19 infection |
|
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Universita degli Studi di Napoli Federico II |
|
Italy |
2020-01-01 |
2020-04-30 |
5/20, I-COVID, NCT04315870 |
Phase Not Applicable |
Recruiting |
1 |
4 Months |
20 |
Gabriele Saccone, Gabriele Saccone, MD |
2020-03-24 |
| UMODCOVID19: Mechanisms for Organ Dysfunction in Covid-19 |
Coronavirus disease 19 infection, SARS coronavirus infection |
blood, urine and sputum sampling alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Uppsala University |
|
Sweden |
2020-03-12 |
2021-12-31 |
EPN 2017/043 COVID19, NCT04316884, UMODCOVID19 |
Phase Not Applicable |
Recruiting |
1 |
21 Months |
100 |
Michael Hultström, MD. PhD., Miklos Lipcsey, MD. PhD., Robert Frithiof, MD. PhD, Robert Frithiof, MD. PhD., Sara Bülow Anderberg, MD. |
2020-03-24 |
| Effects of different VTE prevention methods on the prognosis of hospitalized patients with novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
low molecular weight heparin alone, mechanical preventive anticoagulation therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry |
The First Affiliated Hospital of Guangzhou Medical College |
|
China |
2020-02-10 |
2020-04-10 |
ChiCTR2000030946 |
Phase 4 Clinical |
Recruiting |
1 |
2 Months |
120 |
Chunli Liu |
2020-03-24 |
| A clinical study of leronlimab in patients with respiratory illness due to Coronavirus Disease 2019 (COVID-19) |
Coronavirus disease 19 infection, Respiratory disease |
leronlimab alone |
CCR5 chemokine antagonist |
|
CytoDyn Inc |
|
US |
2020-03-19 |
|
|
Phase 2 Clinical |
Recruiting |
0 |
|
7 |
|
2020-03-31 |
| A clinical study of BNT-162 for the prevention of COVID-19 infection |
Coronavirus disease 19 infection |
BNT-162 alone |
|
|
Shanghai Fosun Pharmaceutical (Group) Co Ltd |
BioNTech SE |
China |
|
|
|
Phase Not Applicable |
Planned |
1 |
|
|
|
2020-03-23 |
| A clinical trial of Remdesivir for potential treatment of COVID-19 |
Coronavirus disease 19 infection |
remdesivir alone |
RNA polymerase modulator |
|
StoneWise |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-03-23 |
| Interferon in treatment of COVID-19 |
Coronavirus disease 19 infection |
Variable regimens including hydroxychloroquine , interferon beta-1a follow-on biologic (subcutaneous), CinnaGen , lopinavir + ritonavir , oseltamivir |
Exo-alpha sialidase inhibitor, HIV protease inhibitor, Interferon beta ligand |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Tehran University of Medical Sciences |
|
Iran |
2020-03-15 |
|
IR.TUMS.VCR.REC.1398.1052, IRCT20100228003449N28 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
|
30 |
Hossein Khalili, Mohammad Ali Sahraian |
2020-03-27 |
| Evaluating efficacy and safety of sofosbuvir + ledipasvir in treatment of COVID-19 |
Coronavirus disease 19 infection |
Variable regimens including hydroxychloroquine , lopinavir + ritonavir , sofosbuvir+ ledipasvir (Danesh Pharmaceutical Development Company) |
HIV protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Tehran University of Medical Sciences |
|
Iran |
2020-03-18 |
|
IR.TUMS.VCR.REC.1398.1074, IRCT20100228003449N29 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
|
50 |
Hossein Khalili, Mohammad Ali Sahraian |
2020-03-26 |
| RECOVERY: Randomized Evaluation Of COVID-19 Therapy |
Coronavirus disease 19 infection, SARS coronavirus infection |
dexamethasone alone, hydroxychloroquine alone, interferon beta-1a alone, lopinavir + ritonavir alone |
HIV protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Oxford |
|
UK |
2020-03-17 |
|
2020-001113-21, NDPHRECOVERY, RECOVERY |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
|
1 |
Martin Landray, Peter Horby |
2020-03-30 |
| TOCIVID-19: Tocilizumab in COVID-19 Pneumonia |
Coronavirus disease 19 infection, Pneumonia, SARS coronavirus infection |
tocilizumab alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Cancer Institute of Naples |
|
Italy |
2020-03-19 |
2022-12-19 |
2020-001110-38, NCT04317092, TOCIVID-19, TOCIVID-19 |
Phase 2 Clinical |
Recruiting |
24 |
33 Months |
330 |
Antonio Mastroianni, MD, Arturo Montineri, MD, Carlo Salvarani, MD, Carmelo Iacobello, MD, Cristina Mussini, MD, Demetrio Labate, Demetrio Labate, MD, Elisabetta Bertelli, MD, Enrico Clini, MD, Evelina Tacconelli, MD, Fabio Franzetti, MD, Fabio Giuliano Numis, MD, Fiorentino Fragranza, MD, Francesco Cristini, MD, Francesco Dentali, MD, Francesco Perrone, MD, PhD, Giancarlo Titolo, MD, Giuseppe Carpinteri, MD, Luca Cabrini, MD, Maria Carmela Piccirillo, MD, Maria Concetta Monea, MD, Maria Danzi, MD, Massimo Girardis, MD, Maurizio Fusari, MD, Paola Faggioli, MD, Paolo Ascierto, MD, Paolo Grossi, MD, Roberto Cauda, MD, Roberto Parrella, MD, Salvo Nicosia, MD, Stobbione Paolo, MD, Vincenzo Montesarchio, MD, Walter Ageno, MD |
2020-03-24 |
| A clinical study to assess Ii-Key-SARS 2 peptide vaccine for the potential treatment of coronavirus disease 19 infection (COVID-19) |
Coronavirus disease 19 infection |
SARS-CoV-2 peptide vaccine (li-Key, COVID-19), Generex alone |
|
|
Generex Biotechnology Corp |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-03-23 |
| STORY: Sero-epidemiological Survey of England in 2019/2020 |
Coronavirus disease 19 infection |
venepuncture alone |
|
Healthy volunteers accepted, Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
University of Oxford |
|
UK |
2019-10-15 |
2020-11-30 |
ID 263097, NCT04061382, STORY |
Phase Not Applicable |
Recruiting |
1 |
13 Months |
2300 |
Helen Rafcliffe, Dr, Iason Vichos, Matthew Snape, Professor |
2020-03-25 |
| Humanistic Care in Patients With Coronavirus Disease 2019 |
Coronavirus disease 19 infection |
Psychological and physical rehabilitation based humanistic care alone, routine therapy alone |
|
|
The Second Hospital of Xi'An Jiaotong University |
|
China |
2020-02-22 |
|
NCT04283825, XJTU2H-WH1 |
Phase Not Applicable |
Terminated |
1 |
|
|
Shouping Gong, MD, PhD |
2020-03-24 |
| Blood Donor Recruitment During Epidemic of COVID-19 |
Coronavirus disease 19 infection |
questionnaire with precaution information alone, questionnaire without precaution information alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Guangzhou Blood Center |
|
China |
2020-03-12 |
2020-04-09 |
BLOOD DONOR RECRUITMENT, NCT04306055 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1500 |
OUYANG Jian |
2020-03-23 |
| Efficacy of a Self-test and Self-alert Mobile Applet in Detecting Susceptible Infection of COVID-19 |
Coronavirus disease 19 infection |
mobile internet survey on self-test (COVID-19 infection self-test and alert system) alone |
|
|
Tsinghua Changgung Hospital |
Chinese Medical Doctor Association, Tsinghua University |
China |
2020-02-01 |
2020-07-31 |
NCT04256395, RWS-BTCH-002 |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
300000 |
Bin Yang, Ph.D, Jiahong Dong, M.D, Xiaobin Feng, M.D, bin yang, Ph.D, chenquan li, D.E, jiahong dong, M.D, xiaobin feng, M.D, xiaojuan wang, Ph.D |
2020-03-24 |
| Identifying Critically-ill Patients With COVID-19 Who Will Benefit Most From Nutrition Support Therapy: Validation of the NUTRIC Nutritional Risk Assessment Tool |
Coronavirus disease 19 infection |
NUTRIC nutritional risk assessment tool (COV_NUTRIC) alone, nutrition support therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry |
Peking University Third Hospital |
Peking University, Queen's University |
China |
2020-02-29 |
2020-07-31 |
COV_NUTRIC, NCT04274322 |
Phase Not Applicable |
Not yet recruiting |
1 |
5 Months |
100 |
Qinggang Ge, M.D., Xiaoxiao Li, M.Sc. |
2020-03-24 |
| Development of a Simple, Fast and Portable Recombinase Aided Amplification Assay for 2019-nCoV |
Coronavirus disease 19 infection, Viral pneumonia |
reverse-transcription RAA (RT-RAA) assay alone |
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Beijing Ditan Hospital |
|
China |
2020-01-01 |
2020-12-31 |
DTXY022, NCT04245631 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
50 |
Xuejun Ma, phD, Yao Xie, Doctor |
2020-03-24 |
| Clinical Outcomes of Patients With COVID-19 |
Coronavirus disease 19 infection |
|
|
|
Guangzhou Institute Of Respiratory Disease, Huizhou Municipal Central Hospital, Guangdong |
|
China |
2020-02-22 |
|
GZHZ-COVID19, NCT04280913 |
Phase Not Applicable |
Terminated |
1 |
|
|
Luqian Zhou, MD |
2020-03-24 |
| Prognositc Factors in COVID-19 Patients Complicated With Hypertension |
Coronavirus disease 19 infection, Hypertension |
ACEI treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Chongqing Medical University |
|
China |
2020-01-25 |
|
2020-02, NCT04272710 |
Phase Not Applicable |
Terminated |
1 |
|
|
Dongying Zhang |
2020-03-25 |
| Humanistic Care in Healthcare Workers in Coronavirus Disease 2019 |
Coronavirus disease 19 infection, Depression, Post traumatic stress disorder |
Humanistic Care alone |
|
|
The Second Hospital of Xi'An Jiaotong University |
|
China |
2020-02-22 |
|
NCT04283838, XJTU2H-WH2 |
Phase Not Applicable |
Terminated |
1 |
|
|
Shouping Gong, MD, PhD |
2020-03-31 |
| A Survey of Psychological Status of Medical Workers and Residents in the Context of 2019 Novel Coronavirus Pneumonia |
Coronavirus disease 19 infection, Psychiatric disorder |
electronic questionnaire alone |
|
Healthy volunteers accepted |
Huazhong University of Science and Technology |
|
China |
2020-02-03 |
2020-04-20 |
IRBID:TJ-C 20200107, NCT04260308 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
30000 |
Xianglin Yuan, Yuhong Dai |
2020-03-23 |
| A New Screening Strategy for 2019 Novel Coronavirus Infection |
Coronavirus disease 19 infection |
minipool testing alone |
|
Healthy volunteers accepted |
No 307 Hospital of the Chinese People’s Liberation Army |
302 Military Hospital of China |
China |
2020-02-29 |
2020-03-31 |
307-NCOV, NCT04281693 |
Phase Not Applicable |
Not yet recruiting |
1 |
1 Month |
230 |
Xiaotian Sun, Yan Liu, Yan Liu, Ph.D., Zheng Lu |
2020-03-25 |
| Evaluation of the Efficacy and Safety of Sarilumab in Hospitalized Patients With COVID-19 |
Coronavirus disease 19 infection, Fever, Viral pneumonia |
sarilumab alone, supportive care alone |
IL-6 receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Regeneron Pharmaceuticals Inc, Sanofi SA |
|
US |
2020-03-16 |
2021-03-16 |
6R88-COV-2040, NCT04315298 |
Phase 2/Phase 3 Clinical |
Recruiting |
0 |
12 Months |
400 |
Clinical Trial Management, Clinical Trials Administrator |
2020-03-31 |
| CovidTox: Adverse Events Related to Treatments Used Against Coronavirus Disease 2019 |
Coronavirus disease 19 infection |
azithromycin alone, chloroquine alone, interferon beta-1a alone, lopinavir + ritonavir alone, remdesivir alone, Variable regimens including azithromycin , chloroquine , interferon beta-1a , lopinavir + ritonavir , remdesivir |
HIV protease inhibitor, RNA polymerase modulator |
|
Groupe Hospitalier Pitie-Salpetriere |
CMC Ambroise Pare |
France |
2020-03-17 |
2023-01-01 |
CIC1421-20-04, CovidTox, NCT04314817 |
Phase Not Applicable |
Recruiting |
1 |
33 Months |
1000 |
Joe-Elie Salem, MD, PhD, Lee S Nguyen, Lee S Nguyen, MD, PhDc |
2020-03-23 |
| Research for the influence of epidemic of novel coronavirus pneumonia (COVID-19) on sleep, psychological and chronic diseases among different populations |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Xiyuan Hospital China Academy Of Chinese Medical Sciences |
|
China |
2020-03-07 |
2020-12-01 |
ChiCTR2000030764 |
Phase Not Applicable |
Recruiting |
1 |
8 Months |
2800 |
Xia Hong |
2020-03-23 |
| Cancelled by the investigator Diagnosis and treatment of novel coronavirus pneumonia (COVID-19) in common and severe cases based on the theory of 'Shi-Du-Yi (damp and plague)' |
Coronavirus disease 19 infection, Viral pneumonia |
damp and plague alone |
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The Second Affiliated Hospital Of Guizhou Medical University |
|
China |
2020-12-01 |
2021-12-31 |
ChiCTR2000030762, ChiMCTR2000003128 |
Phase Not Applicable |
Not yet recruiting |
1 |
13 Months |
100 |
GuoLin Song |
2020-03-23 |
| Continuous renal replacement therapy (CRRT) alleviating inflammatory response in severe patients with novel coronavirus pneumonia (COVID-19) associated with renal injury: a prospective study |
Coronavirus disease 19 infection, Viral pneumonia |
continuous renal replacement therapy (CRRT) alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Lei Shen Shan Hospital, Renji Hospital |
|
China |
2020-04-01 |
|
ChiCTR2000030761 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
20 |
Leyi Gu, Qin Wang |
2020-03-23 |
| Clinical research and preparation development of qingfei detoxification decoction (mixture) for prevention and treatment of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
qingfei detoxification decoction (mixture) therapy alone |
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Affiliated Hospital of Traditional Chinese Medicine of Southwest Medical University |
|
China |
2020-02-18 |
2020-12-31 |
ChiCTR2000030883, ChiMCTR2000003122 |
Phase Not Applicable |
Recruiting |
1 |
10 Months |
100 |
Wang Rao-Qiong, Yang Si-Jin |
2020-03-23 |
| A phase I clinical study of COVID-19 recombinant adenovirus type 5 vector vaccine for the prevention/ treatment of coronavirus disease (COVID-19) |
Coronavirus disease 19 infection |
COVID-19 recombinant adenovirus type 5 vector vaccine (oral enteric-coated tablet, SARS-CoV-2), Vaxart alone |
TLR-3 agonist |
|
Emergent BioSolutions Inc, Vaxart Inc |
|
|
2020-12-31 |
|
|
Phase 1 Clinical |
Planned |
0 |
|
|
|
2020-03-20 |
| COVID-19 Registry |
Coronavirus disease 19 infection |
therapeutic agent therapy alone |
|
|
National Center For Global Health & Medicine |
Japanese Ministry of Health, Labor and Welfare |
Japan |
2020-03-19 |
|
UMIN000039873 |
Phase Not Applicable |
Recruiting |
1 |
|
9999 |
Junko Terada, Norio Ohmagari |
2020-03-23 |
| Treatment of Acute Severe novel coronavirus pneuvirus (COVID-19) With Immunoglobulin From Cured COVID-19 Patients |
Coronavirus disease 19 infection, Viral pneumonia |
immunoglobulin therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Union Hospital Tongji Medical School Huazhong University Of Science & Technology |
Huazhong University of Science and Technology |
China |
2020-02-17 |
2020-05-31 |
ChiCTR2000030841 |
Phase 0 Clinical |
Recruiting |
1 |
3 Months |
10 |
Xiang Cheng |
2020-03-23 |
| Preliminary screening of novel coronavirus pneumonia (COVID-19) by special laboratory examination and CT imaging before surgery |
Coronavirus disease 19 infection |
laboratory examination alone, pulmonary CT alone |
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shanghai Tongren Hospital |
|
China |
2020-03-01 |
2020-04-30 |
ChiCTR2000030839 |
Phase 0 Clinical |
Not yet recruiting |
1 |
2 Months |
100 |
Peng Sun, Yunpeng Zhang |
2020-03-23 |
| A phase II study of Metablok to target inflammation in the lungs caused by viral pneumonia and help reduce related mortality in COVID-19 |
Coronavirus disease 19 infection, Lung inflammation, Viral pneumonia |
Metablok alone |
Dehydropeptidase-1 modulator |
|
Arch Biopartners Inc |
|
|
|
|
|
Phase 2 Clinical |
Planned |
0 |
|
|
|
2020-03-27 |
| COVID MECH: Mechanisms to Morbidity and Mortality for Covid-19 |
Coronavirus disease 19 infection, SARS coronavirus infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Akershus University Hospital |
|
Norway |
2020-03-23 |
2021-12-31 |
117589, COVID MECH, NCT04314232 |
Phase Not Applicable |
Not yet recruiting |
1 |
21 Months |
200 |
Torbjorn Omland |
2020-03-24 |
| A clinical trial of SARS-CoV-2 mRNA vaccine (COVID-19), CureVac in the prevention of coronavirus infection in healthy subjects |
Coronavirus disease 19 infection |
SARS-CoV-2 mRNA vaccine (COVID-19), CureVac alone |
|
Healthy volunteers accepted |
CureVac AG |
|
|
2020-06-30 |
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-03-20 |
| Tocilizumab for SARS-CoV2 Severe Pneumonitis |
Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia |
tocilizumab (intravenous), Roche/Chugai alone |
IL-6 receptor antagonist, IL-6 receptor modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universita Politecnica delle Marche |
Azienda Ospedali Riuniti Marche Nord |
Italy |
2020-03-31 |
2020-05-31 |
NCT04315480, TOCICOV-1 |
Phase 2 Clinical |
Not yet recruiting |
1 |
2 Months |
30 |
Armando Gabrielli |
2020-03-24 |
| Application of blood purification in the treatment of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
blood purification alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Huashan Hospital |
Fudan University |
China |
2020-02-12 |
2020-07-12 |
ChiCTR2000030773 |
Phase Not Applicable |
Recruiting |
1 |
5 Months |
20 |
Jing Qian |
2020-03-23 |
| An anesthesia procedure and extubation strategy for reducing patient agitation and cough after extubation that can be used to prevent the spread of Novel Coronavirus Pneumonia (COVID-19) and other infectious viruses in the operating Room |
Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia |
sevoflurane alone |
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Liaocheng People's Hospital |
|
China |
2020-03-16 |
2020-11-16 |
ChiCTR2000030681 |
Phase 0 Clinical |
Not yet recruiting |
1 |
8 Months |
240 |
Zunyuan Liu |
2020-03-24 |
| The Observational Study of Cardiac and Pulmonary Ultrasound and Evaluation of Treatment of Severe Patients With Novel Coronavirus Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
Cardiopulmonary ultrasound alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Xiangya Hospital Of Central South University |
|
China |
2020-03-20 |
2020-05-31 |
202003028, NCT04314271 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
80 |
Xiao, Zhang Li Na, MD, Zhao Ch Guang, MD |
2020-03-24 |
| A clinical study of mosedipimod for the treatment in patients with COVID-19 infection |
Coronavirus disease 19 infection |
mosedipimod alone |
CCL26 gene inhibitor, TLR modulator |
|
Enzychem Lifesciences Corp |
|
South Korea |
|
|
|
Phase Not Applicable |
Planned |
1 |
|
|
|
2020-03-20 |
| SC2: Identification of host cell respiratory tract cell gene expression and epigenetic pattern after human SARS-CoV-2 infection (COVID-19) |
Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
UniversitätsKlinikum Leipzig |
|
Germany |
2020-03-20 |
|
123/20-ek, DRKS00021134, SC2 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
60 |
Sven Laudi |
2020-03-26 |
| Cohort study of Novel Coronavirus Pneumonia (COVID-19) in children |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Tongji Medical College, Wuhan Children's Hospital |
|
China |
2020-03-10 |
2021-12-31 |
ChiCTR2000030679 |
Phase Not Applicable |
Recruiting |
1 |
21 Months |
500 |
Liu Zhisheng, Xiao Han |
2020-03-24 |
| Clinical study for bronchoscopic alveolar lavage in the treatment of critically trachea intubation patients with new coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
fiberoptic bronchoscopy alone |
|
|
Huazhong University of Science and Technology |
|
China |
2020-03-01 |
2020-04-30 |
ChiCTR2000030857 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
|
Jingjun Yan, Shusheng Li |
2020-03-24 |
| Study for the Psychological Status of Medical Staff of Otolaryngology Head and Neck Surgery in Hubei Province under the Epidemic of novel coronavirus pneumonia (COVID-19) |
Anxiety disorder, Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
Zhangnan Hospital |
|
China |
2020-02-01 |
2021-02-01 |
ChiCTR2000030768 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
450 |
Xiong Chen, Xiuping Yang |
2020-03-24 |
| A clinical study to assess inhaled nitric oxide (NO) system, Lungfit Bro, in COVID-19 patients |
Coronavirus disease 19 infection |
Lungfit Bro alone, nitric oxide (inhalant formulation, cystic fibrosis/bronchiolitis/NTM/COPD/pulmonary hypertension), Beyond Air alone |
|
|
Beyond Air Inc |
|
US |
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-03-20 |
| An artificial intelligence assistant system for suspected novel coronavirus pneumonia (COVID-19) based on chest CT |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tongji Hospital, Huazhong University of Science and Technology |
|
China |
2020-02-15 |
2020-05-15 |
ChiCTR2000030856 |
Phase 0 Clinical |
Recruiting |
1 |
3 Months |
700 |
Liming Xia, Shuchang Zhou |
2020-03-24 |
| A clinical multicenter study for the occurrence, development and prognosis of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Variable regimens including abidor,lopinavir/ritonavir , interferon alfa-2b , lopinavir/ritonavir |
Interferon alpha ligand modulator |
|
The First Affiliated Hospital of college of medicine Zhejiang University |
|
China |
2020-01-22 |
2020-03-15 |
ChiCTR2000030854 |
Phase Not Applicable |
No longer recruiting |
1 |
1 Month |
237 |
Li Lanjuan, Wei Runan |
2020-03-23 |
| A clinical study of remdesivir for the treatment in patients with 2019-nCoV infection |
Coronavirus disease 19 infection |
remdesivir alone |
RNA polymerase modulator |
|
Hong Kong Department of health |
|
Hong Kong |
|
|
|
Phase Not Applicable |
Planned |
2 |
|
|
|
2020-03-20 |
| Study for the effect of external diaphragmatic pacing assisted invasive ventilation and weaning in patients with severe novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
external diaphragmatic pacing alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Zunyi Medical University |
|
China |
2020-02-01 |
2020-05-01 |
ChiCTR2000030855 |
Phase 1 Clinical |
Not yet recruiting |
1 |
3 Months |
200 |
Wen Jianli |
2020-03-24 |
| The prediction value of prognosis of novel coronavirus pneumonia (COVID-19) in elderly patients by modified early warning score (MEWS): a medical records based retrospective observational study |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sun Yat-Sen University |
|
China |
2020-03-09 |
2020-12-31 |
ChiCTR2000030683 |
Phase Not Applicable |
Not yet recruiting |
1 |
9 Months |
198 |
Chen Lei, Zhang Xiaofei |
2020-03-24 |
| A phase III clinical study to assess OT-101 in the treatment of subjects with COVID-19 infection |
Coronavirus disease 19 infection |
trabedersen alone |
TGFB2 gene inhibitor |
|
Mateon Therapeutics Inc |
|
US |
|
|
|
Phase 3 Clinical |
Planned |
0 |
|
|
|
2020-03-23 |
| SISCO: An Observational, Case-control Study of the Use of Siltuximab in ARDS Patients Diagnosed With COVID-19 Infection |
Coronavirus disease 19 infection, Respiratory disease, SARS coronavirus infection |
siltuximab alone |
Heat shock protein inhibitor, IL-6 receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ospedale Papa Giovanni XXIII |
EUSA Pharma |
Italy |
2020-03-19 |
2020-05-19 |
NCT04322188, SISCO, V 0.9 16TH MARCH 2020 |
Phase Not Applicable |
Recruiting |
2 |
2 Months |
50 |
ALESSANDRO RAMBALDI, MD, Alessandro Rambaldi, MD, DIEGO RIPAMONTI, MD, FABIANO DI MARCO, MD, GIUSEPPE GRITTI, MD, Giuseppe GRITTI, MD, Giuseppe Gritti, MD, IVANO RIVA, MD |
2020-03-31 |
| A medical based analysis for influencing factors of death of novel coronavirus pneumonia (COVID-19) patients in Wuhan third hospital |
Coronavirus disease 19 infection, Viral pneumonia |
routine treatment of western medicine alone, traditional Chinese medicine alone |
|
|
Wuhan third Hospital |
|
China |
2020-03-01 |
2020-06-01 |
ChiCTR2000030859 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
1305 |
Guoqin Sun, Meng Luo |
2020-03-24 |
| Clinical characteristics and outcomes of 483 mild patients with novel coronavirus pneumonia (COVID-19) in Wuhan, China during the outbreak: A single-center, retrospective study from the mobile cabin hospital |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hubei Cancer Hospital |
|
China |
2020-02-06 |
2020-03-15 |
ChiCTR2000030858 |
Phase Not Applicable |
Recruiting |
1 |
1 Month |
483 |
Tiejun Wang |
2020-03-23 |
| A medical records based study for clinical characteristics of 2019 novel coronavirus pneumonia (COVID-19) in Zhejiang province, China |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Zhejiang Hospital |
|
China |
2020-02-01 |
2020-03-02 |
ChiCTR2000030760 |
Phase Not Applicable |
No longer recruiting |
1 |
1 Month |
74 |
Hong Wang, Ling Chen |
2020-03-23 |
| A randomized, parallel controlled open-label trial for the efficacy and safety of Prolongin (Enoxaparin Sodium Injection) in the treatment of adult patients with novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
enoxaparin sodium alone, standard treatment alone |
Low molecular weight heparin |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shenzhen Hepalink Pharmaceutical Group Co Ltd, The Third People’s Hospital of Shenzhen |
|
China |
2020-03-10 |
2020-09-30 |
ChiCTR2000030701 |
Phase 0 Clinical |
Not yet recruiting |
1 |
6 Months |
60 |
Cai Qingxian |
2020-03-24 |
| The Use PUL-042 Inhalation Solution to Prevent COVID-19 in Adults Exposed to SARS-CoV-2 |
Coronavirus disease 19 infection, SARS coronavirus infection |
PUL-042 alone |
TLR agonist, TLR-2 agonist, TLR-6 agonist, TLR-9 agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Pulmotect Inc |
|
|
2020-04-30 |
2020-10-31 |
NCT04313023, PUL-042-501 |
Phase 2 Clinical |
Not yet recruiting |
0 |
6 Months |
200 |
Brenton Scott, Ph D, Colin Broom, MD |
2020-03-25 |
| Effect of herbal syrup and solution in treatment of COVID-19 |
Coronavirus disease 19 infection |
standard treatment alone, Coroguard plus Corostop |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Iran University of Medical Sciences |
|
Iran |
2020-03-16 |
|
IR.IUMS.REC.1398.1399, IRCT20200316046792N1 |
Phase 2/Phase 3 Clinical |
Recruiting |
3 |
|
150 |
Amir Hossein Jamshidi, Nader Tavakoli, Seyed Abbas Motevalian |
2020-03-25 |
| A clinical study of virus-neutralizing monoclonal antibodies, for the potential treatment or prevention of coronavirus 19 infection |
Coronavirus disease 19 infection |
virus-neutralizing monoclonal antibodies (COVID-19), Columbia University alone |
|
|
Columbia University |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-03-19 |
| A clinical trial of Polymerase inhibitors for the potential treatment/prevention of coronavirus 19 infection |
Coronavirus disease 19 infection |
Polymerase inhibitors (COVID-19), Columbia University alone |
RNA polymerase inhibitor |
|
Columbia University |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-03-19 |
| A clinical study of protease inhibitors for the potential treatment/prevention of Coronavirus disease 19 infection |
Coronavirus disease 19 infection |
protease inhibitors (Coronavirus disease 19 infection), Columbia University alone |
Protease inhibitor |
|
Columbia University |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-03-19 |
| Exploration of the Clinical Characteristics of Patients with Novel Coronavirus Pneumonia (COVID-19) and Its Differences from Patients with Severe Influenza A and MERS |
Coronavirus disease 19 infection, Influenza virus A infection, Respiratory disorder, SARS coronavirus infection |
|
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shandong Provincial Hospital |
Science and Technology Agency of Shandong Province |
China |
2020-02-01 |
2020-06-30 |
ChiCTR2000030739 |
Phase Not Applicable |
Recruiting |
4 |
5 Months |
100 |
Fenglin Liu, Wenqing Sun |
2020-03-23 |
| Prognosis Investigation and Intervention Study on Patients with novel coronavirus pneumonia (COVID-19) in recovery period Based on Community Health Management |
Coronavirus disease 19 infection, Viral pneumonia |
Glehnia littoralis alone, liriope alone, peach kernel alone, radix notoginseng alone, radix rehmanniae alone, schisandra alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Hubei province hospital of Traditional Chinese Medicine |
Ministry of Science and Technology of the People´s Republic of China |
China |
2020-03-01 |
2020-08-31 |
ChiCTR2000030720 |
Phase 0 Clinical |
Recruiting |
1 |
6 Months |
120 |
Mingzhong Xiao, Xiaodong Li |
2020-03-19 |
| Randomized controlled trial for Chloroquine Phosphate in the Treatment of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
chloroquine phosphate alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Zhangnan Hospital |
|
China |
2020-02-12 |
2020-03-20 |
ChiCTR2000030718 |
Phase 4 Clinical |
Recruiting |
1 |
1 Month |
80 |
Zhao Yan, Zhou Xianlong |
2020-03-19 |
| A Medical Records Based analysis for Risk Factors for Outcomes After Respiratory Support in Patients with ARDS Due to Novel Coronavirus Pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shandong Chest Hospital |
|
China |
2020-02-01 |
2020-08-31 |
ChiCTR2000030763 |
Phase Not Applicable |
Recruiting |
4 |
7 Months |
100 |
Fenglin Liu, Wenqing Sun |
2020-03-19 |
| Study for the therapeutic effect and mechanism of traditional Chinese medicine in the treatment of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Chinese medicine decoction alone, conventional supportive treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The First Affiliated Hospital of Wenzhou Medical University, The Second Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou Central Hospital, Wenzhou Hospital of Traditional Chinese Medicine, Wenzhou Scientific and Technologic Bureau |
|
China |
2020-02-15 |
2020-05-17 |
ChiCTR2000030759, ChiMCTR2000003129 |
Phase 0 Clinical |
Not yet recruiting |
3 |
3 Months |
70 |
Jing-Guo Cheng, Zheng-Zhong Yuan |
2020-03-20 |
| A medical records based study for epidemic and clinical features of novel coronavirus pneumonia (COVID-19) in Ningbo First Hospital |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
Ningbo First Hospital |
|
China |
2020-01-20 |
2020-02-29 |
ChiCTR2000030778 |
Phase Not Applicable |
No longer recruiting |
1 |
1 Month |
40 |
Guoqing Qian, Qian Guoqing |
2020-03-20 |
| Development of warning system with clinical differential diagnosis and prediction for severe type of novel coronavirus pneumonia (COVID-19) patients based on artificial intelligence and CT images |
Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia |
intensive warning system alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Zhangnan Hospital |
|
China |
2020-02-06 |
2020-05-06 |
ChiCTR2000030838 |
Phase Not Applicable |
No longer recruiting |
1 |
3 Months |
500 |
Sun Wenbo, Xu Haibo |
2020-03-24 |
| Novel coronavirus pneumonia (COVID-19) combined with Chinese and Western medicine based on 'Internal and External Relieving - Truncated Torsion' strategy |
Coronavirus disease 19 infection, Viral pneumonia |
Baidu truncated prescription therapy alone, Western medicine routine treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Longhua Hospital Shanghai University of TCM |
|
China |
2020-02-01 |
2020-06-30 |
ChiCTR2000030836, ChiMCTR2000003126 |
Phase 4 Clinical |
Not yet recruiting |
3 |
5 Months |
300 |
Bangjiang Fang |
2020-03-24 |
| Clinical study for the efficacy of Mesenchymal stem cells (MSC) in the treatment of severe novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
human mesenchymal stem cells alone, routine treatment alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Health Commission of Henan Province, The First Affiliated Hospital of Xinxiang Medical University |
|
China |
2020-02-14 |
2021-02-14 |
201100311200, ChiCTR2000030835 |
Phase Not Applicable |
Recruiting |
4 |
12 Months |
20 |
Dou Qifeng, Zhao Jianhua |
2020-03-20 |
| NOpreventCOVID: NO Prevention of COVID-19 for Healthcare Providers |
Coronavirus disease 19 infection, SARS coronavirus infection |
nitric oxide alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Massachusetts General Hospital |
|
US |
2020-03-20 |
2022-03-20 |
NCT04312243, NOPRECOVID-19, NOpreventCOVID |
Phase 2 Clinical |
Not yet recruiting |
0 |
24 Months |
460 |
Lorenzo Berra, Lorenzo Berra, MD |
2020-03-24 |
| Epidemiological Characteristics and Antibody Levels of novel coronavirus pneumonia (COVID-19) of Pediatric Medical Staff working in Quarantine Area |
Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia |
|
|
|
Tongji Hospital, Huazhong University of Science and Technology |
|
China |
2020-03-16 |
2020-03-31 |
ChiCTR2000030834 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
500 |
Jinzhu Zhao, Yan Hao, Xiaoping Luo |
2020-03-24 |
| The Use of PUL-042 Inhalation Solution to Reduce the Severity of COVID-19 in Adults Positive for SARS-CoV-2 Infection |
Coronavirus disease 19 infection, SARS coronavirus infection |
PUL-042 alone, normal care alone |
TLR agonist, TLR-2 agonist, TLR-6 agonist, TLR-9 agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Pulmotect Inc |
|
US |
2020-04-30 |
2020-10-31 |
NCT04312997, PUL-042-502 |
Phase 2 Clinical |
Not yet recruiting |
0 |
6 Months |
100 |
Brenton Scott, Ph D, Colin Broom, MD |
2020-03-25 |
| A Study for Clinical Characteristics of Novel Coronavirus Pneumonia (COVID-19) Patients Follow-up in Guangxi |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
People’s Hospital of Guangxi Zhuang Autonomous Region |
|
China |
2020-01-17 |
2022-01-17 |
ChiCTR2000030784 |
Phase Not Applicable |
Recruiting |
1 |
24 Months |
150 |
Guo Zhang |
2020-03-20 |
| Cancelled by the investigator clinical guidance of diagnose and treatment for novel coronavirus pneumonia (COVID-19) based on 'Shi-Du-Yi' |
Coronavirus disease 19 infection, Viral pneumonia |
traditional Chinese medicine alone |
|
|
The Second Affiliated Hospital Of Guizhou Medical University |
|
China |
2019-12-01 |
2021-12-31 |
ChiCTR2000030765 |
Phase Not Applicable |
Not yet recruiting |
2 |
25 Months |
|
GuoLin Song |
2020-03-20 |
| A double-blind, placebo-controlled clinical study to assess SNG-001 in the treatment of patients with COVID-19 |
Coronavirus disease 19 infection |
inhaled interferon beta (lung disorders/influenza), Synairgen alone |
Interferon beta ligand |
|
Synairgen plc |
|
UK |
|
|
|
Phase 2 Clinical |
Not yet recruiting |
1 |
|
|
|
2020-03-19 |
| The Value of CD4/CD8 cells, CRP/ALB and APACHE II in Novel Coronavirus Pneumonia (COVID-19) |
Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia |
|
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cangzhou People's Hospital |
|
China |
2020-02-01 |
2020-03-31 |
ChiCTR2000030782 |
Phase 1 Clinical |
Recruiting |
1 |
2 Months |
20 |
Lihui Wang |
2020-03-20 |
| Treatment of COVID-19 Patients Using Wharton's Jelly-Mesenchymal Stem Cells |
Coronavirus disease 19 infection, SARS coronavirus infection |
Wharton's Jelly-mesenchymal stem cells alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Stem Cells Arabia |
|
Jordan |
2020-03-16 |
2020-09-30 |
COVID-19, NCT04313322 |
Phase 1 Clinical |
Recruiting |
1 |
6 Months |
5 |
Adeeb Al Zoubi, Adeeb M AlZoubi, Ph.D., Adeeb M Alzoubi, Ph.D., Ahmad AlGhadi, M.Sc., Ahmad Y AlGhadi, M.Sc., Mahasen Zalloum, B.Sc., Marwa E Tapponi, Pharm.D., Sameh N AlBakheet, B.Sc., Sumaya H Aldajah, M.Sc. |
2020-03-20 |
| AI-COVID-Xr: Artificial Intelligence Algorithms for Discriminating Between COVID-19 and Influenza Pneumonitis Using Chest X-Rays |
Coronavirus disease 19 infection |
Chest X-ray alone |
|
|
Grigore T. Popa University of Medicine and Pharmacy |
Falcon Trading Iasi |
Romania |
2020-03-18 |
2020-08-18 |
0110, AI-COVID-Xr, NCT04313946 |
Phase Not Applicable |
Recruiting |
1 |
5 Months |
200 |
Alexandru Burlacu, Lecturer, Alexandru Burlacu, MD, PhD, Alexandru Burlacu, Md, PhD, Professor Adrian Covic, Vice-rector |
2020-03-21 |
| APICTHA: A Phase I Clinical Trial in 18 to 60 Adults |
Coronavirus disease 19 infection, Viral pneumonia |
Ad5-nCoV alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
CanSino Biologics Inc |
Hebei Provincial Center for Disease Control and Prevention, Institute of Biotechnology the Academy of Military Medical Sciences PLA, Jiangsu Province Centers for Disease Control and Prevention, Ministry of Science and Technology of the People´s Republic of China, Tongji Hospital |
China |
2020-03-16 |
2022-12-20 |
APICTHA, ChiCTR2000030906, JSVCT088, NCT04313127 |
Phase 1 Clinical |
Recruiting |
4 |
33 Months |
108 |
Guan Xuhua, Hou Lihua, Wang Wei, Wang Wenjuan, Wang Zhao, Zhu Fengcai |
2020-03-26 |
| Myocardial Damage in COVID-19 |
Coronavirus disease 19 infection, Heart injury |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Wuhan Union Hospital, China |
|
China |
2020-01-01 |
2020-03-18 |
MD-COVID-19, NCT04312464 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
500 |
Xiang Cheng |
2020-03-20 |
| A clinical trial for Ulinastatin Injection in the treatment of patients with severe novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Conventional treatment alone, Ulinastatin alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Shanghai Changzheng Hospital |
|
China |
2020-03-16 |
2020-05-31 |
ChiCTR2000030779 |
Phase 4 Clinical |
Recruiting |
2 |
2 Months |
100 |
Yi Shan, Zhaofen Lin,Wansheng Chen,Weifen Xie |
2020-03-20 |
| SOTSPC: Sequential Oxygen Therapy Strategy for Patients With COVID-19 |
Coronavirus disease 19 infection |
non-invasive positive pressure ventilation alone, oxygen alone, standard treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Henan Province People's Hospital |
|
China |
2020-02-01 |
2021-02-28 |
NCT04312100, SOT-C, SOTSPC |
Phase Not Applicable |
Recruiting |
1 |
13 Months |
30 |
Li Li, Master, Xiaoju Zhang, PhD, Ziqi Wang, MD |
2020-03-23 |
| Plasma of the convalescent in the treatment of novel coronavirus pneumonia (COVID-19) common patient: a prospective clinical trial |
Coronavirus disease 19 infection, Viral pneumonia |
convalescent plasma alone, conventional treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
China-Japan Friendship Hospital, Institute of Blood Transfusion, Chinese Academy of Medical Sciences |
|
China |
2020-02-15 |
2020-08-15 |
ChiCTR2000030702 |
Phase 0 Clinical |
Recruiting |
4 |
6 Months |
50 |
Cao Bin, Liu Zhong |
2020-03-20 |
| A phase II clinical trial to evaluate the safety and immunogenicity of mRNA-1273 in the treatment of patients with coronavirus COVID-19 infection |
Coronavirus disease 19 infection |
mRNA-1273 alone |
Moesin modulator |
|
ModeRNA Therapeutics |
|
|
|
|
|
Phase 2 Clinical |
Planned |
0 |
|
|
|
2020-03-19 |
| A clinical trial of HIV drug in combination with chloroquine for the treatment of patients with novel coronavirus COVID-19 infection |
Coronavirus disease 19 infection |
HIV drug alone, chloroquine alone |
|
|
University of Queensland Centre for Clinical Research |
|
Australia |
|
|
|
Phase Not Applicable |
Planned |
1 |
|
|
David Paterson |
2020-03-19 |
| CoV-19POC: Does point-of-care testing for coronavirus in hospital improve patient care compared to laboratory testing? |
Coronavirus disease 19 infection |
QIAstat-Dx Respiratory n-CoV Panel alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Southampton NHS Foundation Trust |
|
UK |
2020-02-07 |
2021-04-01 |
CoV-19POC, IRAS 280621, ISRCTN14966673, RHM MED1696 |
Phase Not Applicable |
Recruiting |
2 |
13 Months |
500 |
Dr Clark |
2020-03-20 |
| A randomized, blinded, controlled, multicenter clinical trial to evaluate the efficacy and safety of ixekizumab combined with conventional antiviral drugs in patients with novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
antiviral therapy alone, ixekizumab alone |
IL-17 antagonist, Interleukin 17A ligand inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
The Third Xiangya Hospital of Central South University, Xiangya Hospital Of Central South University |
|
China |
2020-03-10 |
2020-05-31 |
ChiCTR2000030703 |
Phase 0 Clinical |
Recruiting |
2 |
2 Months |
40 |
Pinhua Pan, Yehong Kuang |
2020-03-20 |
| Observation Of Clinical Efficacy And Safety Of Bufonis Venenum Injection In The Treatment Of Severe Novel Coronavirus Pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Bufonis venenum alone |
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Jiangsu Province Hospital of TCM |
|
China |
2020-02-10 |
2020-03-10 |
ChiCTR2000030704, ChiMCTR2000003105 |
Phase 2 Clinical |
Recruiting |
1 |
1 Month |
25 |
Hu Xingxing |
2020-03-20 |
| Study for the efficacy and safety of Prolongin (Enoxaparin Sodium Injection) in treatment of novel coronavirus pneumonia (COVID-19) adult common patients |
Coronavirus disease 19 infection, Viral pneumonia |
Prolongin alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shenzhen Hepalink Pharmaceutical Group Co Ltd, Union Hospital Tongji Medical School Huazhong University Of Science & Technology |
|
China |
2020-03-09 |
2020-09-30 |
ChiCTR2000030700 |
Phase 0 Clinical |
Not yet recruiting |
1 |
6 Months |
60 |
Cao Guanhua, Zhang Yu |
2020-03-24 |
| Clinical validation and application of high-throughput novel coronavirus (2019-nCoV) screening detection kit |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Male |
Tongji Hospital, Huazhong University of Science and Technology |
|
China |
2020-03-22 |
2020-03-31 |
ChiCTR2000030833 |
Phase 0 Clinical |
Not yet recruiting |
1 |
|
400 |
Chen Guang, Ning Qin |
2020-03-20 |
| COVID-AIV: Intravenous Aviptadil for COVID-19 Associated Acute Respiratory Distress |
Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia |
aviptadil (inhaled, sarcoidosis/acute lung injury), Relief Therapeutics Holding alone, maximal intensive care alone |
Adrenergic receptor antagonist, VIP receptor agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
NeuroRx Inc |
Relief Therapeutics Holding AG |
US, Israel |
2020-04-30 |
2020-09-30 |
COVID-AIV, COVID-AIV, NCT04311697 |
Phase 2 Clinical |
Not yet recruiting |
1 |
5 Months |
120 |
Jonathan C Javitt, MD, MPH, Robert E Besthof, MIM, Yaron Bar-Lavie, MD, FCCP |
2020-03-30 |
| Yinhu Qingwen Granula for the Treatment of Severe CoVID-19 |
Coronavirus disease 19 infection |
Yinhu Qingwen granula alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
China Academy of Chinese Medical Sciences |
Tangshan People's Hospital, The First Affiliated Hospital of Dalian Medical University |
China |
2020-03-20 |
2021-06-30 |
NCT04310865, YHQW-SEVERE-V2.0 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
4 |
15 Months |
116 |
Dong Shang, Dong Shang, M.D., Dong-Feng Shao, Gui-Fang Li, Jiang-Rong Huang, M.D., Jun Liu, M.D., Peiyan Du, Xiao-Dong Li, M.D., Xin-Rong Liu, Ya-Lan Song, Yan-Ling Hu, Yu Zhang, Zhong Wang, M.D. |
2020-03-19 |
| Losartan for Patients With COVID-19 Requiring Hospitalization |
Coronavirus disease 19 infection, SARS coronavirus infection |
losartan alone |
Angiotensin II AT-1 receptor antagonist, Angiotensin II receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Minnesota |
|
US |
2020-03-16 |
2021-04-01 |
NCT04312009, SURG-2020-28675-I |
Phase 2 Clinical |
Not yet recruiting |
0 |
12 Months |
200 |
Christopher Tignanelli, MD, David Wacker, MD, Jeffrey Chipman, MD, Michael Puskarich, MD, MS, Michelle Biros, MD, MS, Nicholas Ingraham, MD, Ron Reikoff, MD, Timothy Schacker, MD |
2020-03-24 |
| Favipiravir Combined With Tocilizumab in the Treatment of Coronavirus Disease 2019 |
Coronavirus disease 19 infection |
favipiravir plus tocilizumab |
RNA polymerase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Peking University First Hospital |
|
China |
2020-03-08 |
2020-05-31 |
2020YFC0844100, NCT04310228 |
Phase 2 Clinical |
Recruiting |
11 |
2 Months |
150 |
Dingyu Zhang, Guiqiang Wang, Haichao Li, Hong Zhao, Qin Ning, Qing Mao, Xi Zheng, Xianxiang Chen, Xihai Xu, Yu Hu, Yuhong Qin, Zhenshun Cheng |
2020-03-19 |
| Development and Verification of a New Coronavirus Multiplex Nucleic Acid Detection System |
Coronavirus disease 19 infection, SARS coronavirus infection |
QIAstat-Dx alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Huashan Hospital |
|
China |
2020-03-14 |
2020-12-01 |
KY2020-COVID-19, NCT04311398 |
Phase Not Applicable |
Not yet recruiting |
1 |
8 Months |
100 |
Chao Qiu, Jiazhen Chen, Jing Wu, Jingwen Ai, Mengqi Zhu, Wen-hong Zhang, Wenhong Zhang, Doctor, Wenhong Zhang, PhD,MD, Yanmin Wan, Zhongliang Shen |
2020-03-24 |
| A diagnostic study to detect SARS-CoV-2, the virus that causes COVID-19 disease through Hologic’s Panther Fusion SARS-CoV-2 assay |
Coronavirus disease 19 infection |
Hologic’s Panther Fusion SARS-CoV-2 assay alone |
|
|
Hologic Inc |
|
US |
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-03-18 |
| A clinical trial of AmnioBoost, in patients with acute respiratory distress syndrome (ARDS) caused by coronavirus (COVID-19) |
Coronavirus disease 19 infection, Respiratory distress syndrome |
AmnioBoost alone |
|
|
Lattice Biologics Inc |
|
US |
|
|
|
Phase 1 Clinical |
Recruiting |
0 |
|
10 |
|
2020-03-19 |
| A single-arm, Chinese clinical trial to assess the efficacy of tocilizumab in severe patients with Corona Virus Disease-19 (COVID-19) |
Coronavirus disease 19 infection |
routine therapy alone, tocilizumab alone |
|
Asian Ancestry |
2nd People's Hospital of Fuyang City, Anhui Provincial Hospital, South District of the First Affiliated Hospital of University of Science and Technology of China |
|
China |
|
|
|
Phase 2 Clinical |
Status not specified |
1 |
|
21 |
|
2020-03-18 |
| Evaluation of the protective effect of dexmedetomidine on patients with severe novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
dexmedetomidine alone |
Alpha 2 adrenoceptor agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The First People’s Hospital of Zunyi |
Zunyi science and technology bureau |
China |
2020-02-01 |
2020-05-31 |
ChiCTR2000030853 |
Phase 0 Clinical |
Not yet recruiting |
1 |
4 Months |
200 |
Wen Jianli |
2020-03-24 |
| Losartan for Patients With COVID-19 Not Requiring Hospitalization |
Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia |
losartan alone |
Angiotensin II AT-1 receptor antagonist, Angiotensin II receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Minnesota |
|
US |
2020-03-16 |
2021-04-01 |
NCT04311177, SURG-2020-28675-O, SURG-2020-28683 |
Phase 2 Clinical |
Not yet recruiting |
0 |
12 Months |
516 |
Christopher Tignanelli, MD, David Wacker, MD, Jeffrey Chipman, MD, Michael Puskarich, MD, MS, Michelle Biros, MD, MS, Nicholas Ingraham, MD, Ron Reikoff, MD, Timothy Schacker, MD |
2020-03-24 |
| A clinical trial of Kevzara for the treatment of symptoms of novel coronavirus infections outside of the U.S |
Coronavirus disease 19 infection |
sarilumab alone |
IL-6 receptor antagonist |
|
Regeneron Pharmaceuticals Inc, Sanofi SA |
|
Italy |
|
|
|
Phase Not Applicable |
Planned |
1 |
|
|
|
2020-03-18 |
| Factors associated with death in patients with novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Beijing Anzhen Hospital, Capital Medical University |
|
China |
2020-01-27 |
2020-02-27 |
ChiCTR2000030852 |
Phase Not Applicable |
Completed |
1 |
1 Month |
150 |
Jiang Xie |
2020-03-24 |
| Impact of Novel Coronavirus Pneumonia (COVID-19) Epidemic Period on the Management of Investigator-Initiated Clinical Trial and the Resilience of Medical Service Providers |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
Clinical Research Institute, Shenzhen-Peking University |
|
China |
2020-03-13 |
2020-06-30 |
ChiCTR2000030757 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
100 |
Zhang Yue |
2020-03-19 |
| A medical records based study for sedation and analgesia usage in critically ill patients with novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
sedation and analgesia treatment alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tongji Hospital |
|
China |
2020-03-10 |
2020-04-30 |
ChiCTR2000030758 |
Phase Not Applicable |
Not yet recruiting |
3 |
1 Month |
200 |
Zhigang He |
2020-03-19 |
| Cross sectional study of dialysis treatment and mental status under the outbreak of novel coronavirus pneumonia (COVID-2019) in China |
Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression, Kidney dialysis |
dialysis alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
West China Hospital |
|
China |
2020-03-10 |
2020-04-02 |
ChiCTR2000030708 |
Phase Not Applicable |
Recruiting |
1 |
|
1000 |
Hui Zhong |
2020-03-19 |
| Retrospective study on novel coronavirus pneumonia (COVID-19) in Tibetan Plateau |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
West China Hospital |
|
China |
2020-03-20 |
2022-03-19 |
ChiCTR2000030707 |
Phase Not Applicable |
Not yet recruiting |
1 |
24 Months |
78 |
LIijia Deng, Teresa Teng |
2020-03-19 |
| Detection of SARS-CoV-2 in EPS/semen of patients with novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shenzhen Hospital of Southern Medical University, Wuhan third Hospital, Xiangyang Central Hospital |
|
China |
2020-02-20 |
2020-08-20 |
ChiCTR2000030756 |
Phase 0 Clinical |
Recruiting |
3 |
6 Months |
60 |
Qingyou Zheng, Weihe Quan |
2020-03-19 |
| A medical records based study for characteristics, prognosis of ederly patients with Novel Coronavirus Pneumonia (COVID-19) in Wuhan area |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tongji Hospital |
|
China |
2020-03-15 |
2020-09-15 |
ChiCTR2000030755 |
Phase Not Applicable |
Not yet recruiting |
1 |
6 Months |
400 |
Cuntai Zhang, Hongyu Gao |
2020-03-19 |
| Medical records based study for the accuracy of SARS-CoV-2 IgM antibody screening for diagnosis of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
The Third Affiliated Hospital of Sun Yat-Sen University |
|
China |
2020-03-11 |
2020-06-30 |
ChiCTR2000030754 |
Phase Not Applicable |
No longer recruiting |
1 |
3 Months |
30 |
Dabiao Chen, Zhanlian Huang |
2020-03-19 |
| A medical records based analysis of the Incidence and Risk Factors of Ventilator-associated Pneumonia in ARDS Patients with Novel Coronavirus Pneumonia (COVID-19) |
Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia |
|
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shandong Chest Hospital |
|
China |
2020-02-01 |
2020-08-31 |
ChiCTR2000030753 |
Phase Not Applicable |
Suspended |
4 |
7 Months |
100 |
Fenglin Liu, Wenqing Sun |
2020-03-19 |
| Correlation analysis of blood eosinophil cell levels and clinical type category of novel coronavirus pneumonia (COVID-19): a medical records based retrospective study |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Japanese Ancestry |
Tongji Hospital, Huazhong University of Science and Technology |
|
China |
2020-03-16 |
2020-06-16 |
ChiCTR2000030862 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
150 |
Feng Gao, Zheng Li |
2020-03-20 |
| A medical records based analysis for risk factors for death in patients with Novel Coronavirus Pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shandong Chest Hospital |
|
China |
2020-02-01 |
2020-08-31 |
ChiCTR2000030752 |
Phase Not Applicable |
Recruiting |
4 |
7 Months |
500 |
Fenglin Liu, Wenqing Sun |
2020-03-19 |
| Clinical research for traditional mongolian medicine in the treatment of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
traditional mongolian medicine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
The Affiliated Hospital of Inner Mongolia Medical University |
|
China |
2020-01-25 |
2020-12-25 |
ChiCTR2000030751 |
Phase Not Applicable |
Not yet recruiting |
1 |
11 Months |
60 |
Burenbatu, Zhiqiang Han |
2020-03-19 |
| A medical records based study for clinical outcomes and follow-up of novel coronavirus pneumonia (COVID-19) patients |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tongji Hospital, Huazhong University of Science and Technology |
|
China |
2020-02-18 |
2021-03-30 |
ChiCTR2000030809 |
Phase Not Applicable |
Recruiting |
1 |
13 Months |
1000 |
Xu Shuyun |
2020-03-23 |
| Clinical characteristics and prognosis of cancer patients with novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia |
bioinformatics alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tongji Medical College |
|
China |
2020-02-10 |
2020-03-30 |
ChiCTR2000030807 |
Phase Not Applicable |
Recruiting |
10 |
1 Month |
100 |
Xianglin Yuan, Zhihua Wang |
2020-03-19 |
| Investigation on psychological status of novel coronavirus pneumonia (COVID-19) rehabilitation patients in Zhengzhou City and research on coping strategies |
Coronavirus disease 19 infection, Viral pneumonia |
Psychological intervention alone |
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
People’s Hospital of Zhengzhou |
|
China |
2020-03-01 |
2021-03-01 |
ChiCTR2000030849 |
Phase 0 Clinical |
Not yet recruiting |
1 |
12 Months |
81 |
Qingyan Pei, Yibin Hao |
2020-03-19 |
| Cancelled by the investigator Application of cas13a-mediated RNA detection in the assay of novel coronavirus nucleic acid (COVID-19) |
Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia |
cas13a-mediated RNA application alone |
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Zunyi Medical University |
|
China |
2020-02-09 |
2020-12-31 |
ChiCTR2000030706 |
Phase 0 Clinical |
Recruiting |
1 |
10 Months |
|
Guangtao huang, Jingjie Tan |
2020-03-24 |
| Study for immune cell subsets in convalescent patients with novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The Third Affiliated Hospital of the Second Military Medical University |
|
China |
2020-02-10 |
2021-02-10 |
ChiCTR2000030690 |
Phase 2 Clinical |
Recruiting |
2 |
12 Months |
30 |
Tang Hao, Wang Hongyang |
2020-03-24 |
| Novel coronavirus pneumonia (COVID-19) associated kidney injury in children |
Coronavirus disease 19 infection, Hematuria, Proteinuria, Renal disease, Renal injury |
Bailing alone, renal replacement therapy alone |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Wuhan medical care center for women and children |
|
China |
2020-02-01 |
2020-10-31 |
ChiCTR2000030687 |
Phase 0 Clinical |
Not yet recruiting |
1 |
9 Months |
120 |
Qi Chang, Wang Xiaowen |
2020-03-18 |
| The effects of prevention and control measures on treatment and psychological status of cancer patients during the novel coronavirus pneumonia (COVID-19) outbreak |
Cancer, Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Peking University Third Hospital |
|
China |
2020-03-03 |
2020-07-03 |
ChiCTR2000030686 |
Phase Not Applicable |
Recruiting |
1 |
4 Months |
300 |
Baoshan Cao, Yane Liu |
2020-03-18 |
| A comparative study for the sensitivity of induced sputum and throat swabs for the detection of SARS-CoV-2 by real-time PCR in patients with novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia |
induced sputum alone, throat swab alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
The Affiliated Hospital of Guangdong Medical College |
|
China |
2020-03-16 |
2020-04-26 |
ChiCTR2000030721 |
Phase 0 Clinical |
Not yet recruiting |
2 |
1 Month |
|
Huanqin Han |
2020-03-24 |
| Development and application of novel coronavirus pneumonia (COVID-19) intelligent image classification system based on deep learning |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
The 2nd People's Hospital of Ningbo |
|
China |
2020-03-01 |
2020-12-31 |
ChiCTR2000030830 |
Phase Not Applicable |
Recruiting |
1 |
10 Months |
150 |
Jiaying Xu, Jingfeng Zhang |
2020-03-18 |
| The analysis of related factors on improving oxygenation status by endotracheal intubation ventilation in severe patients suffered from novel coronavirus pneumonia (COVID-19): a single-center and descriptive study in Wuhan |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tongji Hospital, Huazhong University of Science and Technology |
|
China |
2020-03-16 |
2020-06-15 |
ChiCTR2000030831 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
75 |
Ye Tu, Zheng Li |
2020-03-18 |
| A clinical study for effectiveness and safety evaluation for recombinant chimeric COVID-19 epitope DC vaccine in the treatment of novel coronavirus pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
COVID-19 epitope gene recombinant chimeric DC vaccine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
The Third People’s Hospital of Shenzhen |
|
China |
2020-03-01 |
2021-02-28 |
ChiCTR2000030750 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
2 |
12 Months |
120 |
Jing Yuan, Zhenlin Zhao |
2020-03-18 |