Last updated: Apr 08, 2020 - 02:00 +0100

Title Indication Intervention Actions PatientSelection Sponsor Collaborator Country StartDate EndDate Identifiers Phase Recruitment Status Sites Trial Duration Enrollment Count Contacts LastChanged
FingoCov: Effect of Fingolimod for treatment of COVID-19-induced cytokine storm Coronavirus disease 19 infection, Viral pneumonia fingolimod alone, standard regimen alone Cannabinoid receptor antagonist, Sphingosine-1-phosphate receptor-1 modulator, Sphingosine-1-phosphate receptor-3 modulator, Sphingosine-1-phosphate receptor-4 modulator, Sphingosine-1-phosphate receptor-5 modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tabriz University of Medical Sciences Iran 2020-04-08 FingoCov, IR.TBZMED.REC.1399.001, IRCT20200317046797N2 Phase 3 Clinical Not yet recruiting 1 40 Dr Khalil Ansarin, Dr Mohammad Samiei, Mohammadreza Ardalan, Sepideh Zununi Vahed 2020-04-06
EPI-COVID-19: Household Transmission Investigation Study for COVID-19 in French Guiana Coronavirus disease 19 infection, SARS coronavirus infection Blood sample alone, Nasopharyngeal swab alone Healthy volunteers accepted Institut Pasteur Centre Hospitalier de Cayenne, Institut Pasteur de Guyane French Guiana 2020-03-23 2022-03-23 2020-009, EPI-COVID-19, NCT04328129 Phase Not Applicable Recruiting 0 24 Months 450 Claude Flamand, PhD, Claude Flamand, Phd, Dominique Rousset, MD 2020-04-06
Evaluation of the effect of traditional Iranian medicine product on improvement of clinical manifestation of COVID-19 Coronavirus disease 19 infection Traditional Medicine (Astragalus gossypinus with food spice) alone Kerman University of Medical Sciences Iran 2020-03-24 IR.KMU.REC.1399.003, IRCT20101219005416N2 Phase 3 Clinical Recruiting 1 80 Haleh Tajadini 2020-04-06
Comparison of efficacy of oral levamisole and formoterol + budesonide inhaler with standard treatment of Corona infection Coronavirus disease 19 infection Variable regimens including budesonide + formoterol fumarate, AstraZeneca , hydroxychloroquine sulfate , levamisole (Poursina pharmaceutical Company) , lopinavir + ritonavir Beta 2 adrenoceptor agonist, HIV protease inhibitor Fasa University of Medical Sciences Iran 2020-04-01 IR.FUMS.REC.1399.002, IRCT20200324046852N1 Phase 2/Phase 3 Clinical Recruiting 0 30 Dr. Jalal Karimi, Dr. Mojtaba Farjaam, Dr. Siamack Afazeli, Dr.Siamack Afazeli 2020-04-06
Supplementation in COVID-19 Coronavirus disease 19 infection Soluvit (Fresenius Kabi New Zealand) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Tehran University of Medical Sciences Iran 2020-04-02 IR.TUMS.VCR.REC.1399.090, IRCT20200319046819N1 Phase 3 Clinical Recruiting 0 60 Dr. Mohammad Ali Sahraian, Sama Bitarafan 2020-04-06
A clinical study to assess KL4 surfactant for treatment of lung injury resulting from severe COVID-19 infection Coronavirus disease 19 infection, Lung injury lucinactant (aerosol), Windtree Therapeutics/ Esteve/ Lee's Pharmaceutical alone BMP10 gene inhibitor, BMP15 gene inhibitor Windtree Therapeutics Inc Phase Not Applicable Planned 0 2020-04-06
The effect of dental pulp mesenchymal stem cells in treatment of corona virus disease Coronavirus disease 19 infection, Viral pneumonia dental pulp mesenchymal stem cells alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kerman University of Medical Sciences Iran 2020-04-04 IR.KMU.REC.1399.018, IRCT20140911019125N6 Phase 2 Clinical Recruiting 2 10 Abbas Pardakhty, Alireza Farsinejad, Mehrdad Farrokhnia 2020-04-06
HOPE: Chroloquine Phosphate Against Infection by the Novel Coronavirus Coronavirus disease 19 infection, Viral pneumonia chroloquine phosphate, Uni-Pharma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories Sa Greece 2020-04-02 2020-001345-38, HOPE, UNIKINON-01/HOPE Phase 2 Clinical No longer recruiting 1 60 Regulatory Affairs department 2020-04-06
COVID-19 in Patients With HIV Coronavirus disease 19 infection, SARS coronavirus infection University of Missouri US 2020-04-01 2020-10-01 262095, NCT04333953 Phase Not Applicable Recruiting 0 6 Months 500 Dima Dandachi, Dima Dandachi, MD 2020-04-06
COVITD-19: Vitamin D on Prevention and Treatment of COVID-19 Coronavirus disease 19 infection ACE2 inhibitor therapy alone, Angiotensin II Receptor Blockers therapy alone, NSAIDs therapy alone, Vitamin D alone, thiazolidinediones therapy alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Granada Spain 2020-04-10 2020-06-30 COVITD-19, COVITD-19, NCT04334005 Phase Not Applicable Not yet recruiting 2 2 Months 200 Manuel J Castillo, MD, PhD, Manuel J. Castillo Garzón, Proffesor Amaro Gahete, PhD student 2020-04-06
Effect of Camostate mesylate on the outcome of Coronavirus (COVID-19)-induced pneumonia Coronavirus disease 19 infection, Viral pneumonia camostat mesylate alone, standard regimen alone Serine protease inhibitor, Trypsin inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tabriz University of Medical Sciences Iran 2020-04-08 IR.TBZMED.REC.1398.1312, IRCT20200317046797N1 Phase 3 Clinical Not yet recruiting 1 40 Dr Khalil Ansarin, Mohammad Reza Ardalan, Sepideh Zununi Vahed 2020-04-06
Escape: Management of Novel SARS Coronavirus Coronavirus disease 19 infection, Multiple organ failure anakinra alone, tocilizumab (intravenous), Roche/Chugai alone IL-6 receptor antagonist, IL-6 receptor modulator, Type I IL-1 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hellenic Institute for the Study of Sepsis Greece 2020-04-01 2020-001039-29, Escape Phase 2 Clinical Recruiting 1 20 President of the Board 2020-04-06
Effect of febuxostat against coronavirus Coronavirus disease 19 infection, Lung injury acetaminophen plus febuxostat Xanthine oxidase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mazandaran University of Medical Sciences Iran 2020-03-16 2020-04-09 IR.MAZUMS.REC.1398.1452, IRCT20190727044343N1 Phase 3 Clinical No longer recruiting 1 60 Lotfollah Davoodi, Majid Saeedi 2020-04-06
Clinical study for prevention and treatment of digestive tract lesions caused by novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Gastrointestinal disease, Viral pneumonia chloroquine plus rabeprazole H+ K+ ATPase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Fifth Affiliated Hospital, Sun Yat-Sen University China 2020-02-12 2021-07-31 ChiCTR2000031454 Phase 0 Clinical Recruiting 1 17 Months Xiao Fei 2020-04-06
Novel coronavirus (2019-nCOV) IgG detection kit (magnetic particle chemiluminescence) clinical trial Coronavirus disease 19 infection, Viral pneumonia 2019-nCov IgG test alone, PCR Nucleic acid detection alone First People's Hospital of Jiangxia District, Wuhan (Union Jiangnan Hospital) Taizhou Zecheng Biotechnology Co. Ltd. China 2020-03-25 2021-03-31 ChiCTR2000031465 Phase 0 Clinical Not yet recruiting 1 12 Months 200 Pang Jifeng, Xiang Changgang 2020-04-06
Sleep quality of patients with novel coronavirus pneumonia (COVID-19) treated in mobile cabin hospital: a retrospective study Coronavirus disease 19 infection, Viral pneumonia earplugs alone, eye patch alone Shanghai East Hospital China 2020-02-10 2020-02-25 ChiCTR2000031499 Phase Not Applicable Completed 1 55 Li Chen, Ma Shaolin 2020-04-06
Effect of hydroxychloroquine on prevention of Covid-19 virus Coronavirus disease 19 infection, Viral infection hydroxychloroquine, Amin Pharmaceutical alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Tehran University of Medical Sciences Iran 2020-03-29 IR.TUMS.VCR.REC.1399.001, IRCT20120826010664N6 Phase 2 Clinical Recruiting 1 310 Mohammad Ali Sahraian, Reihaneh Pirjani, Reihaneh Pirjani MD. 2020-04-06
A multicenter, randomized Phase II clinical trial of plitidepsin for the treatment of patients with COVID-19 pneumonia Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia plitidepsin alone Elongation factor 1 alpha 2 modulator, VEGF-1 receptor modulator PharmaMar SA Spain Phase 2 Clinical Planned 1 160 2020-04-06
The Effect of Tanacetum parthenium (L) sch Syrup on Clinical Manifestations of Patients with COVID-19 Coronavirus disease 19 infection, Respiratory tract infection Trachyspermum copticum syrup (Barij Essence and Shahid Beheshti Pharmaceutical Group) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ghoum University of Medical Sciences Iran 2020-04-07 IR.MUQ.REC.1399.012, IRCT20180610040049N4 Phase 3 Clinical Not yet recruiting 1 60 Ehsan Sharifipour, Mohammad KamaliNejad, Mohsen Bahrami, Reza Shirvani 2020-04-06
Impact of measuring distance and cold outdoor environment on the screening of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia cold outdoor environment alone, temperature measuring distance alone Young Adults (18-44 yrs) Peking University First Hospital China 2020-03-07 2020-04-12 ChiCTR2000031500 Phase 0 Clinical No longer recruiting 1 1 Month 58 LI HANG, PENG RUI 2020-04-06
Study of the effect of vitamin C in patients with COVID-19 Coronavirus disease 19 infection Variable regimens including chloroquine phosphate (Pars) , hydroxychloroquine sulfate (Tehran) , lopinavir + ritonavir , vitamin C HIV protease inhibitor Abadan School of Medical Sciences Iran 2020-04-19 IR.ABADANUMS.REC.1398.119, IRCT20200324046850N5 Phase 2 Clinical Not yet recruiting 1 40 Sara Mobarak, سارا مبارک 2020-04-06
The efficacy of convalescent plasma in patients with critical novel coronavirus pneumonia (COVID-19): a pragmatic, prospective cohort study Coronavirus disease 19 infection, Viral pneumonia convalescent plasma alone, routine treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Nanjing General Hospital of Nanjing Military Command, PLA China 2020-03-17 2020-07-17 ChiCTR2000031501 Phase 0 Clinical Not yet recruiting 1 4 Months 20 Lu Ke, Weiqin Li 2020-04-06
Effects of nano curcumin supplementation on the reduction of inflammation and mortality in patients with coronavirus 2019 admitted to ICU ward of Imam Reza hospital in Tabriz Coronavirus disease 19 infection Variable regimens including hydroxychloroquine , lopinavir , nano curcumin, Exir Sina , oseltamivir , ribavirin Exo-alpha sialidase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tabriz University of Medical Sciences Iran 2020-03-29 IR.TBZMED.REC.1398.1314, IRCT20200324046851N1 Phase 2/Phase 3 Clinical Recruiting 1 86 Hamed Valizadeh, Hassan soleimanpor, Majid Ahmadi, Ramin Pourakbari 2020-04-06
A Prospective Study on Corona Virus Disease 2019 Patients Whose Nucleic Acids Changed From Negative to Positive Coronavirus disease 19 infection favipiravir alone RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Peking University First Hospital China 2020-04-01 2020-09-15 2020 RESEARCH 112, NCT04333589 Phase 2 Clinical Not yet recruiting 8 5 Months 210 Dingyu Zhang, Guiqiang Wang, Hong Zhao, Junhua Yu, Sibin Zhang, Xianfeng Han, Xianxiang Chen, Xinghuan Wang, Xinsheng Chen, Yongping Chen 2020-04-06
A phase II/III clinical study to assess leronlimab in the treatment of critically ill patients with COVID-19 infection Coronavirus disease 19 infection leronlimab alone CCR5 chemokine antagonist CytoDyn Inc Phase 2/Phase 3 Clinical Planned 0 342 2020-04-06
Chloroquine for Mild Symptomatic and Asymptomatic COVID-19 Coronavirus disease 19 infection chloroquine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) HaEmek Medical Center 2020-04-30 2021-12-31 EMC 0045-20, NCT04333628 Phase 2/Phase 3 Clinical Not yet recruiting 0 20 Months 210 Lee Goldstein, MD, gilat ron avraham 2020-04-06
Hydroxychloroquine in Outpatient Adults With COVID-19 Coronavirus disease 19 infection hydroxychloroquine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sanofi SA US 2020-03-31 2020-05-31 2020-001269-35, EFC16855, NCT04333654, U1111-1249-6168 Phase 1b Clinical Recruiting 0 2 Months 210 Clinical Sciences & Operations 2020-04-06
Covid-VAS: Outcomes of Vascular Surgery in COVID-19 Infection: National Cohort Study Coronavirus disease 19 infection vascular surgery alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sociedad Espanola de Angiologia y Cirugia Vascular Spain 2020-04-01 2020-11-01 Covid-VAS, NCT04333693, RIV-2020-1 Phase Not Applicable Not yet recruiting 1 7 Months 50 Alvaro Torres, MD, PhD, Carlos Vaquero, MD, PhD, Prof, Enrique M San Norberto, MD, PhD, MsC, Investigator Council, Joaquin de Haro, MD, PhD, Jorge Cuenca, MD, PhD, Jorge Fernández-Noya, MD, PdD, Luis Riera, MD, PhD, Raul Lara, MD, PhD, Sergi Bellmunt, MD, PhD 2020-04-06
Study for the Mechanism of the Relationship between Infection of novel coronavirus pneumonia (COVID-19) and Host Innate Immune Coronavirus disease 19 infection, Viral pneumonia isolate blood monocyte therapy alone Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) 2nd People's Hospital of Fuyang City, Institute of Blood Transfusion, Chinese Academy of Medical Sciences China 2020-04-20 2021-04-20 ChiCTR2000031627 Phase 0 Clinical Not yet recruiting 0 12 Months 60 Shasha Li, Xiuyong Li 2020-04-06
Clinical study for Celebrex in the treatment of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia celecoxib alone Cyclooxygenase 2 inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Guangzhou 8th People's Hospital China 2020-02-17 2020-06-17 ChiCTR2000031630 Phase 0 Clinical Recruiting 1 4 Months 60 Hong wenxin 2020-04-06
Application of non-invasive multichannel cardiopulmonary monitoring cloud management platform in patients with Novel Coronavirus Pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia non-invasive multi-channel cardiopulmonary monitor alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shanghai Sixth People’s Hospital China 2020-04-01 2022-10-31 ChiCTR2000031503 Phase Not Applicable Not yet recruiting 1 31 Months 100 Chen Yu, Shen Chengxing 2020-04-06
A phase II clinical study to assess ifenprodil in the treatment of patients with COVID-19 infection Coronavirus disease 19 infection ifenprodil (long-acting, oral, COVID-19/acute lung injury), Nash Pharmaceuticals alone NMDA receptor epsilon 2 subunit inhibitor Algernon Pharmaceuticals Novotech (Australia) Pty Ltd Australia Phase 2 Clinical Planned 1 2020-04-06
An investigator-initiated feasible phase II clinical study to assess ifenprodil in the treatment of patients with COVID-19 infection Coronavirus disease 19 infection ifenprodil (long-acting, oral, COVID-19/acute lung injury), Nash Pharmaceuticals alone NMDA receptor epsilon 2 subunit inhibitor Asian Ancestry Algernon Pharmaceuticals Novotech (Australia) Pty Ltd South Korea Phase 2 Clinical Planned 1 2020-04-06
Efficacy and safety of Nintedanib esilate soft capsules in the treatment of pulmonary fibrosis in healed moderate to severe patients of novel coronavirus pneumonia (COVID-19): a single-center, randomized, placebo-controlled trial Coronavirus disease 19 infection, Pulmonary fibrosis, Viral pneumonia nintedanib alone CSF-1 antagonist, FGF receptor antagonist, FGF1 receptor antagonist, FGF2 receptor antagonist, FGF3 receptor antagonist, Flt3 tyrosine kinase inhibitor, Lck tyrosine kinase inhibitor, Lyn tyrosine kinase inhibitor, PDGF receptor alpha antagonist, PDGF receptor antagonist, PDGF receptor beta antagonist, Src tyrosine kinase inhibitor, VEGF receptor antagonist, VEGF-1 receptor antagonist, VEGF-2 receptor antagonist, VEGF-3 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Tongji Hospital, Huazhong University of Science and Technology China 2020-04-02 2020-08-01 ChiCTR2000031453 Phase 4 Clinical Not yet recruiting 1 4 Months 80 Huilan Zhang, Xianglin Yuan 2020-04-06
A Phase III Study to Assess The Effect of Ruxolitinib in Combination with Standard of Care (SoC) Therapy, Compared to SoC Therapy Alone, in Patients With Severe COVID-19 Pneumonia Following Infection With SARS-CoV-2 Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia Standard of Care (SoC) alone, ruxolitinib (oral, myeloproliferative disorders), Incyte/Novartis alone Jak1 tyrosine kinase inhibitor, Jak2 tyrosine kinase inhibitor Novartis AG Incyte Corp Phase 3 Clinical Planned 0 2020-04-06
A Medical Records Based Study for the Correlation between Angiotensin II Type 1 Receptor Blockers (ARBs) and the Progression and Outcome of Novel Coronavirus Pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Wuhan medical care center for women and children China 2019-03-15 2020-06-30 ChiCTR2000031539 Phase Not Applicable Not yet recruiting 3 15 Months 180 Zhang Hua-nian 2020-04-06
A multicenter, national, follow-up study to evaluate the effectiveness of convalescent serum therapy against the COVID-19 virus infection Coronavirus disease 19 infection convalescent serum therapy alone Houston Methodist US Phase Not Applicable Planned 0 2020-04-06
Study for clinical effect of rehabilitation nursing program for patients with novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia rehabilitation Nursing Program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Zunyi Medical University China 2020-02-05 2020-12-05 ChiCTR2000031540 Phase 1 Clinical Recruiting 1 10 Months 100 Huang Di, Jiang ZhiXia 2020-04-06
A paired clinical study for novel coronavirus pneumonia (COVID-19) patients with ordinary, severe, critical, and deceased patients in Tongji Hospital Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Huazhong University of Science and Technology China 2020-01-27 2022-12-31 ChiCTR2000031587 Phase 0 Clinical Recruiting 1 35 Months 2000 Xiaomei Guo 2020-04-06
COVID-19 Symptom Tracker Coronavirus disease 19 infection COVID-19 symptom tracker app alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) King's College London Harvard TH Chan School of Public Health, Massachusetts General Hospital, Stanford University, Zoe Global Ltd UK, US 2020-03-23 2022-03-23 COVID-19 SYMPTOM TRACKER, NCT04331509 Phase Not Applicable Recruiting 1 24 Months 10000000 Andrew Chan, Andrew T. Chan, MD, David A Drew, PhD, Tim D Spector, Victoria Vazquez 2020-04-06
QUARANTINE2020: Chloroquine as Antiviral Treatment in Coronavirus Infection 2020 Coronavirus disease 19 infection, SARS coronavirus infection chloroquine phosphate alone, standard of care alone, telemedical supervision alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Wroclaw Medical University 2020-04-06 2020-12-31 NCT04331600, QUARANTINE2020, QUARANTINE2020 Phase 4 Clinical Not yet recruiting 0 8 Months 400 Marta Duda-Sikula, MBA 2020-04-06
COVIPRIM: Accompanying monitoring of primary care in GP practices during the COVID-19 pandemic Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Medical University of Graz, Paracelsus Medical University J.W. Goethe University Hospital Austria, Germany 2020-04-03 20-619, COVIPRIM, DRKS00021231 Phase Not Applicable Not yet recruiting 2 2000 Ms. Dr. Dagmar Schaffler 2020-04-06
PrEP_COVID: Pre-exposure Prophylaxis With Hydroxychloroquine for High-risk Healthcare Workers During the COVID-19 Pandemic Coronavirus disease 19 infection, SARS coronavirus infection hydroxychloroquine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Barcelona Institute for Global Health Hospital Clinic of Barcelona, Laboratorios Rubio SA Spain 2020-04-03 2020-10-30 NCT04331834, PREP_COVID, PrEP_COVID Phase 3 Clinical Not yet recruiting 1 6 Months 440 Jose Munoz Gutierrez, MD, PhD 2020-04-06
Timely Diagnosis and Treatment Shortens the Time to Resolution of Coronavirus Disease (COVID-19) Pneumonia and Lowers the Highest and Last computed tomography (CT) criteria Scores From Sequential Chest CT Coronavirus disease 19 infection, Viral pneumonia computed tomography (CT) scoring criteria alone American Roentgen Ray Society China Phase Not Applicable Status not specified 1 25 Erpeng Cai, Guangbin Wang, Guoquan Huang, Jianwen Wang, Liangjie Lin, Shirong Li, Tao Gong, Xiaohu Li, Xinfu Guo, Yongqiang Yu 2020-04-06
DIIC19: Efficacy of dexamethasone, IV-IG and Interferone beta for treatment of patients with severe COVID-19 Coronavirus disease 19 infection standard treatment alone, Variable regimens including dexamethasone , hydroxychloroquine , interferon beta , intravenous immunoglobulin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Gorgan University of Medical Sciences Iran 2020-04-18 2020-06-19 DIIC19, IR.GOUMS.REC.1399.004, IRCT20120225009124N4 Phase 2 Clinical Not yet recruiting 1 2 Months 105 Dr Nafiseh Abdolahi, Gholamreza Roshandel, Mohammadreza Honarvar 2020-04-06
The effectiveness of mindfulness intervention in improving people's psychological and physical well-being during novel coronavirus pneumonia (COVID-19) outbreak Coronavirus disease 19 infection, Viral pneumonia mindfulness exercise alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Asian Ancestry China European International Business School (CEIBS) China 2020-02-20 2020-03-02 ChiCTR2000031272 Phase Not Applicable Completed 1 110 Zheng Xue 2020-04-06
ACTION: Azithromycin for COVID-19 Treatment in Outpatients Nationwide Coronavirus disease 19 infection, SARS coronavirus infection azithromycin alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of California San Francisco US 2020-04-01 2021-07-30 20-30504, ACTION, NCT04332107 Phase 3 Clinical Not yet recruiting 0 15 Months 2271 Catherine Cook, MPH, Catherine Oldenburg, ScD, MPH, Jessica M Brogdon, MPH, Thuy Doan, MD, PhD 2020-04-03
Hyperbaric Oxygen for COVID-19 Patients Coronavirus disease 19 infection, Respiratory distress syndrome hyperbaric oxygen alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) NYU Langone Health US 2020-04-30 2020-07-31 NCT04332081, S20-00399 Phase 2 Clinical Not yet recruiting 0 3 Months 40 David Lee, David Lee, MD, Scott Gorenstein 2020-04-06
C19REG: COVID-19 Public Image Registry Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) RAD-AID International BioClinica Inc, Google Inc US 2020-03-30 2025-03-30 C19REG, C19REG, NCT04331860 Phase Not Applicable Recruiting 0 60 Months 500000 Dan Gebow, PhD, Daniel Mollura, MD, TBD TBD 2020-04-06
CP-COVID-19: Convalescent Plasma for Patients With COVID-19: A Pilot Study Coronavirus disease 19 infection, Viral pneumonia convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Del Rosario University CES University, Fundación Universitaria de Ciencias de la Salud, Instituto Distrital de Ciencia Biotecnologia e Innovacion en salud Colombia 2020-04-01 2020-12-31 ABN011-1, CP-COVID-19, NCT04332380 Phase 2 Clinical Not yet recruiting 1 9 Months 10 Adriana Rojas Villarraga, MD, Anha M Robledo Moreno, Bernardo Camacho Rodríguez, MD, MSc, Carlos E Perez, MD, Cristian A Ricaurte Perez, MSc, Diana M Monsalve Carmona, PhD, Gustavo A Salguero López, MD, PhD, Gustavo Quintero, MD, MSc, Heily C Ramírez Santana, MSc, PhD, Isaura P Torres Gómez, MSc, PhD, Jeser S Grass Guaqueta, MSc, Juan C Diaz Coronado, MD, MSc, Juan E Gallo Bonilla, MSc, PhD, Juan M Anaya Cabrera, MD, PhD, Luisa P Duarte Correales, Manuel E Rojas Quintana, MD, MSc, Oscar M Gómez Guzmán, MSc, PhD, Paula A Pedroza Rodríguez, Paula Gaviria, MSc, Ruben D Manrique Hernández, MSc, PhD, Ruben D Mantilla, MD, Sara Velez Gomez, Yeny Y Acosta Ampudia, PhD, Yhojan A Rodríguez Velandia, MD 2020-04-06
An adaptive, multicenter, randomized controlled clinical study to evaluate the safety and efficacy of IFX-1 in patients with severe COVID-19 pneumonia Coronavirus disease 19 infection, Viral pneumonia IFX-1 alone Complement C5a factor inhibitor InflaRx GmbH Netherlands Phase Not Applicable Recruiting 1 2020-04-03
A Study to Assess The Effect Of AP-1189 in the Treatment of Coronavirus Disease 19 Infection (COVID-19) Patients Coronavirus disease 19 infection AP-1189 alone Melanocortin MC1 receptor agonist, Melanocortin MC3 receptor agonist SynAct Pharma ApS Phase Not Applicable Planned 0 2020-04-03
COVID-Lambda: Mild COVID-19 Peginterferon Lambda Coronavirus disease 19 infection, SARS coronavirus infection peginterferon lambda-1a alone, standard of care treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Stanford University US 2020-04-15 2022-05-31 55619, COVID-Lambda, NCT04331899 Phase 2 Clinical Not yet recruiting 0 25 Months 120 Julie Parsonnet, Upinder Singh 2020-04-06
A clinical trial of Veyonda in patients at risk of developing COVID-19 associated acute respiratory distress syndrome (ARDS) and multi-organ failure Coronavirus disease 19 infection, Multiple organ failure, Respiratory distress syndrome idronoxil (suppository, cancer), Noxopharm alone CASP8-FADD-like regulator inhibitor, Ecto NOX disulfide thiol exchanger 2 inhibitor, Sphingosine kinase inhibitor, Sphingosine-1-phosphate receptor-1 antagonist, Stimulator of interferon genes protein stimulator, Topoisomerase inhibitor, X-linked inhibitor of apoptosis protein inhibitor Noxopharm Ltd Phase Not Applicable Planned 0 2020-04-06
CORIMUNO-TOC: Cohort, Multiple, Randomized, Controlled Trials, Open-label of Immune Modulatory Drugs and Other Treatments in COVID-19 Patients - Tocilizumab Trial - CORIMUNO-19 - TOCI Coronavirus disease 19 infection, Viral pneumonia tocilizumab alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris 2020-03-31 2021-12-31 APHP200375-1, CORIMUNO-TOC, NCT04331808 Phase 2 Clinical Not yet recruiting 0 21 Months 240 Matthieu RESCHE-RIGON, MD PhD, Olivier HERMINE, MD-PhD 2020-04-06
Evaluation of Efficacy of Levamisole and Formoterol + Budesonide in Treatment of COVID-19 Coronavirus disease 19 infection Variable regimens including budesonide + formoterol , hydoxychloroquine , levamisole , lopinavir + ritonavir HIV protease inhibitor Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fasa University of Medical Sciences Iran 2020-03-31 2020-05-20 97548, NCT04331470 Phase 2/Phase 3 Clinical Not yet recruiting 1 1 Month 30 Mojtaba Farjaam, MD, Siamack Afazeli, Siamack Afazeli, Pharm.D 2020-04-06
TOCOVID: Clinical Trial of Combined Use of Hydroxychloroquine, Azithromycin, and Tocilizumab for the Treatment of COVID-19 Coronavirus disease 19 infection, SARS coronavirus infection Variable regimens including azithromycin , hydroxychloroquine , tocilizumab Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) FUNDACIÓ INSTITUT DE RECERCA DE L'HOSPITAL DE LA SANTA CREU I SANT PAU Instituto de Salud Carlos III 2020-04-30 2020-10-31 IIBSP-COV-2020-23, NCT04332094, TOCOVID Phase 2 Clinical Not yet recruiting 0 6 Months 276 Pere Domingo, MD, PhD 2020-04-06
GO2 PEEP: Bidirectional Oxygenation Valve in the Management of Pulmonary Complications of COVID-19 Coronavirus disease 19 infection GO2 PEEP Mouthpiece alone, PEEP therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Emory University US 2020-04-30 2020-04-30 GO2 PEEP, NCT04331366, STUDY00000381 Phase Not Applicable Not yet recruiting 0 5 Jeffrey Miller, MD 2020-04-06
Tofacitinib in SARS-CoV2 Pneumonia Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia tofacitinib alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Universita Politecnica delle Marche Italy 2020-04-10 2020-07-10 NCT04332042, TOFACOV Phase 2 Clinical Not yet recruiting 1 3 Months 50 Armando Gabrielli, Armando Gabrielli, Prof, Giovanni Pomponio, Dr 2020-04-06
COVID CALL 15: Epidemiological Observation From a Smartphone Self-monitoring Application for Suspected COVID-19 Patient's Triage Coronavirus disease 19 infection Moovcare alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Weprom Assistance Publique Hopitaux de Paris, DOCAPOSTE, Direction generale de l'offre de soins, Institut Pasteur France 2020-03-17 2020-07-31 COVID CALL 15, NCT04331171, WP-2020-02 Phase Not Applicable Recruiting 1 4 Months 15000000 Fabrice DENIS, MD 2020-04-06
An Observational Study of Patients With Coronavirus Disease 2019 (COVID-19) Coronavirus disease 19 infection, SARS coronavirus infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) TARGET PharmaSolutions, Inc US 2020-04-30 2021-03-31 NCT04331886, TARGET-COVID-19 Phase Not Applicable Not yet recruiting 0 11 Months 5000 Chuck Moser 2020-04-06
COVIDOSE: Tocilizumab to Prevent Clinical Decompensation in Hospitalized, Non-critically Ill Patients With COVID-19 Pneumonitis Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia tocilizumab alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Chicago US 2020-04-03 2020-12-01 COVIDOSE, IRB20-0515, NCT04331795 Phase 2 Clinical Not yet recruiting 0 7 Months 50 Pankti Reid, MD, MPH 2020-04-06
INHASCO: Protective Role of Inhaled Steroids for Covid-19 Infection Coronavirus disease 19 infection Usual practice alone, budesonide + formoterol fumarate, AstraZeneca alone Beta 2 adrenoceptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Assistance Publique Hopitaux de Paris France 2020-04-30 2020-07-31 2020-001306-35, INHASCO, NCT04331054, P 200394 Phase 3 Clinical Not yet recruiting 1 3 Months 436 Bruno CRESTANI, MD, PhD, Camille TAILLE, MD, PhD 2020-04-06
Study on home pharmaceutical care for chronic patients over the novel coronavirus pneumonia (COVID-19) epidemic Coronavirus disease 19 infection, Viral pneumonia Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) People's hospital of Zhengzhou University China 2020-03-12 2021-03-11 ChiCTR2000031176 Phase Not Applicable Recruiting 1 12 Months 100 Zhang Yi 2020-04-06
The efficacy of intravenous immunoglobulin (IVIg) in patients with severe COVID-19 who have not responded to standard three-drug protocol Coronavirus disease 19 infection intravenous immunoglobulin alone, heparin plus intravenous immunoglobulin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Mashhad University of Medical Sciences Iran 2020-04-04 IR.MUMS.REC.1399.013, IRCT20200325046859N1 Phase 2 Clinical Recruiting 1 50 Dr Mohsen Tafaghodi, Rozita Khodashahi 2020-04-06
Safety and Efficacy of CAStem for Severe COVID-19 Associated With/Without ARDS Coronavirus disease 19 infection, Respiratory distress syndrome human embryonic stem cells derived M cells (CAStem) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Asian Ancestry Chinese Academy of Sciences Beijing YouAn Hospital China 2020-01-27 2020-12-31 CHINESEASZQ-006, NCT04331613 Phase 1/Phase 2 Clinical Recruiting 1 11 Months 9 Hao Jie, Doctor, Wang Liu, Doctor, Zhou Qi, Doctor 2020-04-06
A Phase I, First in Human trial to Assess The Effect of OpenCorona, Karolinska Institutet In Treatment of Coronavirus disease 19 infection (COVID-19) Patient Coronavirus disease 19 infection SARS-CoV-2 vaccine (coronavirus COVID-19 infection), Karolinska Institutet alone Cobra Biologics Holding AB, The European Union Sweden Phase 1 Clinical Planned 1 2020-04-03
Nosocomial infection of coronavirus disease 2019 in the hospital without negative pressure chamber Coronavirus disease 19 infection, Infectious disease Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Oita San-ai Medical Center Japan 2020-04-02 UMIN000040033 Phase Not Applicable Recruiting 1 300 Ryota Sagami 2020-04-06
A clinical study of trans sodium crocetinate in patients with Acute Respiratory Distress Syndrome (ARDS) associated with COVID-19 infection Coronavirus disease 19 infection, Respiratory distress syndrome trans sodium crocetinate (intravenous), Diffusion Pharmaceuticals alone Diffusion Pharmaceuticals LLC, University of Virginia US Phase Not Applicable Planned 0 Dr. Andrew Southerland 2020-04-03
COLCOV19-BX: COVID-19 Biological Samples Collection Coronavirus disease 19 infection, SARS coronavirus infection biological sampling alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Bordeaux France 2020-04-02 2023-03-31 CHUBX 2020/11, COLCOV19-BX, NCT04332016 Phase Not Applicable Recruiting 1 35 Months 2000 Aurelie POUZET, Aurélie POUZET, Isabelle PELLEGRIN 2020-04-06
A proof-of-concept clinical trial to assess rhu-pGSN in the treatment of patients suffering from severe lung injury due to COVID-19 pneumonia Coronavirus disease 19 infection, Lung injury, Viral pneumonia gelsolin, BioAegis Therapeutics alone Actin antagonist BioAegis Therapeutics Inc US Phase Not Applicable Planned 0 2020-04-06
SARS-RAS: Renin-angiotensin System Inhibitors and COVID-19 Coronavirus disease 19 infection, Hypertension, SARS coronavirus infection RAS inhibitor therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Societa Italiana dell'Ipertensione Arteriosa Italy 2020-03-10 2020-04-30 NCT04331574, SARS-RAS, SARS-RAS Phase 4 Clinical Recruiting 1 1 Month 2000 Claudio Borghi, MD, Claudio Ferri, MD, Guido Grassi, MD, Guido Iaccarino, MD, Guido Iaccarino, MD, PhD, Leonardo Sechi, MASSIMO VOLPE, MD, MariaLorenza Muiesan, MD, Marialorenza Muiesan 2020-04-06
A randomized, double-blind, phase II clinical study to assess efficacy and safety of APN-01 in the treatment of patients with COVID-19 Coronavirus disease 19 infection APN-01 alone Angiotensin converting enzyme 2 stimulator Apeiron Biologics GmbH Denmark, Germany, Austria Phase 2 Clinical Not yet recruiting 3 200 2020-04-03
Study of the Efficacy and Safety of Ruxolitinib to Treat COVID-19 Pneumonia Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia Standard of Care (SoC) alone, ruxolitinib (oral, myeloproliferative disorders), Incyte/Novartis alone Jak1 tyrosine kinase inhibitor, Jak2 tyrosine kinase inhibitor Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Incyte Corp, Novartis AG, The University Health Network Canada 2020-04-06 2021-01-31 20-5315, NCT04331665, U-DEPLOY: RUX-COVID Phase 3 Clinical Not yet recruiting 1 9 Months 64 Steven Chan, M.D., Vikas Gupta, M.D. 2020-04-06
A clinical study to assess anti-androgen therapy in patients with COVID-19 infection Coronavirus disease 19 infection anti-androgen therapy alone Applied Biology Inc US Phase Not Applicable Planned 0 Andy Goren, MD 2020-04-04
A clinical study to assess safety and efficacy of Lambda in the treatment of patients with COVID-19 Coronavirus disease 19 infection peginterferon lambda-1a, Eiger BioPharmaceuticals alone Interferon receptor modulator, Interleukin-29 ligand Eiger BioPharmaceuticals Inc US Phase Not Applicable Planned 0 2020-04-03
Comparison of The Therapeutic Effect of Convalescent Plasma and Plasma-derived Immunoglobulin-enriched solution on COVID-19 Patients Coronavirus disease 19 infection convalescent plasma alone, plasma-derived immunoglobulin-enriched solution alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Ahvaz University of Medical Sciences Iran 2020-03-24 IR.AJUMS.REC.1399.003, IRCT20200310046736N1 Phase 2/Phase 3 Clinical Not yet recruiting 1 45 Mandana Puladzadeh, Mehdi Safdarian, Mohammad Badavi 2020-04-06
Treatment of patients with Coronavirus infection Coronavirus disease 19 infection, Respiratory distress syndrome Septimeb alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Tehran University of Medical Sciences Iran 2020-03-28 IR.TUMS.VCR.REC.1399.041, IRCT20200324046847N1 Phase 2 Clinical Recruiting 1 30 Dr. Mohammad Ali Sahraian, Hamidreza Khorram Khorshid, Minoo Mohraz 2020-04-06
COV-AID: Treatment of COVID-19 Patients With Anti-interleukin Drugs Coronavirus disease 19 infection, Respiratory failure anakinra alone, siltuximab alone, tocilizumab (intravenous), Roche/Chugai alone, Variable regimens including anakinra , siltuximab , tocilizumab (intravenous), Roche/Chugai Heat shock protein inhibitor, IL-6 receptor antagonist, IL-6 receptor modulator, Type I IL-1 receptor antagonist Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitair Ziekenhuis Gent Belgium Health Care Knowledge Centre Belgium 2020-04-30 2020-12-31 COV-AID, COV-AID, NCT04330638 Phase 4 Clinical Not yet recruiting 9 8 Months 342 Anja Delporte, Bart Lambrecht, MD, PhD, CyrJean Yombi, MD PhD, Elisabeth Dewaele, Manu Malbrain, MD PhD, Maya Hites, MD PhD, Necsoi Coca, MD, Olivier Malaise, Sebastien Anguille, MD, Stefaan Vandecasteele, MD 2020-04-06
Comparison of the safety and efficacy of favipiravir and Kaletra in COVID-19 Coronavirus disease 19 infection routine care alone, favipiravir plus hydroxychloroquine RNA polymerase inhibitor Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bagheiat-allah University of Medical Sciences Iran 2020-04-01 IR.BMSU.REC.1399.017, IR.IUMS.REC.1399.065, IRCT20200318046812N1 Phase 3 Clinical Recruiting 11 324 Dr Behzad Einollahi, Dr Farhad Zamani, Dr Farzaneh Dastan, Dr Hossein Khalili, Dr Mansooreh Momen Heravi, Dr Mariam Qaraati, Dr Mohamad Memarian, Dr Mostafa Ghanee, Dr Ramin Sami, Dr Roya Qasemian, Dr Saeid Kalantari, Dr Shadi Ziaei, Dr. Mostafa Ghanei, Hossein Biganeh 2020-04-06
Effect of Licorice in COVID-19 Coronavirus disease 19 infection licorice extract syrup alone, standard treatment alone Artesh University of Medical Sciences Iran 2020-03-23 IR.AJAUMS.REC.1398.267, IRCT20160316027081N1, LCT-19 Phase 3 Clinical Recruiting 4 374 Dr. Ali Asgari, Dr. Amir Ezzati, Dr. Saeed Soleiman Meigooni, Dr. Saeed Soleiman-Meigooni, Dr.Mohammad Aminianfar, Dr.Saeed Soleiman-Meigooni, Ramin Hamidi Farahani 2020-04-02
A Trial of Ciclesonide in Adults With Mild COVID-19 Coronavirus disease 19 infection, SARS coronavirus infection ciclesonide (metered dose inhaler), Teijin/Covis/AstraZeneca alone Glucocorticoid receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Korea University Guro Hospital South Korea 2020-04-01 2020-09-30 KUMC-COVID-19, NCT04330586 Phase 2 Clinical Not yet recruiting 1 6 Months 141 Joon Young Song, MD, PhD, Woo Joo Kim, Professor 2020-04-06
A clinical study of first plasma therapy for the treatment of COVID-19 infection Coronavirus disease 19 infection convalescent serum therapy alone Houston Methodist US Phase Not Applicable Recruiting 0 Eric Salazar, M.D., Ph.D 2020-04-06
CORONACION: Coronavirus ACEi/ARB Investigation Coronavirus disease 19 infection, Hypertension, SARS coronavirus infection amlodipine alone, bendroflumethiazide alone, chlorothiazide alone, chlorthalidone alone, diltiazem alone, felodipine alone, hydrochlorothiazide alone, indapamide alone, metolazone alone, nicardipine alone, nifedipine alone, nimodipine alone, nitrendipine alone, verapamil alone Calcium channel inhibitor, Calcium channel inhibitor L-type Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National University of Ireland Galway Ireland 2020-03-30 2021-03-01 C.A. 2348, C.A. 2628, CORONACION, NCT04330300 Phase 4 Clinical Recruiting 1 11 Months 2414 Chee Hwui Liew, MSc, Darren Mylotte, MBBCh PhD, Faisal Sharif, MBBS PhD, John William McEvoy, MBBCh MHS 2020-04-03
A small field study to detect SARS-CoV-2 in unselected patient samples Coronavirus disease 19 infection pool testing of SARS-CoV-02 samples alone infektiologikum frankfurt Phase Not Applicable Status not specified 0 50 2020-04-02
A validation study to test the efficacy of at-home COVID-19 test for the diagnosis of COVID19 infection Coronavirus disease 19 infection at-home COVID-19 test alone Care Access Research US Phase Not Applicable Status not specified 0 500 2020-04-03
EPICOS: Clinical Trial for the Prevention of Infection in Healthcare Personnel Coronavirus disease 19 infection, SARS coronavirus infection hydroxychloroquine alone, tenofovir disoproxil fumarate + emtricitabine alone, hydroxychloroquine plus tenofovir disoproxil fumarate + emtricitabine Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Effice Servicios Para la Investigacion Spain 2020-04-01 2020-07-31 EPICOS, NCT04329520, PREP COVID-19 Phase 3 Clinical No longer recruiting 1 4 Months 4000 Julia del Amo, PhD 2020-04-03
A study of INOpulse inhaled nitric oxide system (iNO) in a patient with novel coronavirus disease (COVID-19) Coronavirus disease 19 infection nitric oxide (inhaled, INOpulse), Bellerophon alone Bellerophon Therapeutics LLC US 2020-03-31 Phase Not Applicable Recruiting 0 2020-04-03
HOPE: Hydroxychloroquine as Post Exposure Prophylaxis for SARS-CoV-2 Coronavirus disease 19 infection, SARS coronavirus infection hydroxychloroquine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gangnam Severance Hospital South Korea 2020-04-01 2022-03-30 3-2020-0036, HOPE, NCT04330144 Phase 3 Clinical Not yet recruiting 1 23 Months 2486 Yong Goo Song, Professor 2020-04-03
Evaluation of the effects of losartan in patients with Coronavirus disease 2019 Coronavirus disease 19 infection losartan alone, routine treatment protocol alone Angiotensin II AT-1 receptor antagonist, Angiotensin II receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tabriz University of Medical Sciences Iran 2020-03-31 IR.TBZMED.REC.1399.002, IRCT20180802040678N4 Phase 3 Clinical Recruiting 1 100 Akbar Sharifi, Armin Sadeghi, Mohammad Samiei 2020-04-06
Randomized, Controlled, Double-blind Clinical Trial Comparing the Efficacy and Safety of Chemoprophylaxis With Hydroxychloroquine in Patients Under Biological Treatment and/or JAK Inhibitors in the Prevention of SARS-CoV-2 Infection Coronavirus disease 19 infection, SARS coronavirus infection hydroxychloroquine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Fundacion Instituto de Investigacion Marques de Valdecilla, IDIVAL 2020-04-06 2020-11-06 ENCOVID-HIDROXICLOROQUINA, NCT04330495 Phase 4 Clinical Not yet recruiting 0 7 Months 800 Javier Crespo, MDPhD 2020-04-06
Non-invasive Detection of Pneumonia in Context of Covid-19 Using Gas Chromatography - Ion Mobility Spectrometry (GC-IMS) Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia BreathSpec alone, breath test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) NHS Lothian 2020-03-25 2020-03-25 282014, NCT04329507 Phase Not Applicable Not yet recruiting 0 200 Michael Eddleston 2020-04-03
CATCO: Treatments for COVID-19: Canadian Arm of the Solidarity Trial Coronavirus disease 19 infection, SARS coronavirus infection lopinavir + ritonavir alone, standard of care alone HIV protease inhibitor Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sunnybrook Health Sciences Centre AbbVie Inc Canada 2020-03-18 2022-05-18 2114, CATCO, NCT04330690 Phase 2 Clinical No longer recruiting 1 26 Months 440 2020-04-03
PERN-COVID-19: Clinical Characteristics and Outcomes of Pediatric COVID-19 Coronavirus disease 19 infection, SARS coronavirus infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) University of Calgary Canada 2020-03-18 2022-03-17 NCT04330261, PERN-COVID-19, REB18-0107-MOD9 Phase Not Applicable Recruiting 1 24 Months 12500 Anna Funk, PhD, Stephen Freedman, MD, Stephen Freedman, MDCM, MSc 2020-04-03
Efficacy and Safety of Hydroxychloroquine and Azithromycin for the Treatment of Hospitalized Patients With Moderate to Severe COVID-19 Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia standard care alone, azithromycin plus hydroxychloroquine sulfate Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Azidus Brasil Prevent Senior Private Operadora de Saúde LTDA 2020-04-03 2020-06-30 HIAPRE0320OR, NCT04329572 Phase 0 Clinical Not yet recruiting 0 2 Months 400 Alvaro Razuk Filho, Carla Morales Guerra Godoy, MD, PhD, Luciana Ferrara 2020-04-03
ALBERTA HOPE-Covid19: Hydroxychloroquine to Prevent Covid19 Pneumonia Coronavirus disease 19 infection, SARS coronavirus infection Plaquenil alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Calgary Canada 2020-04-08 2020-08-31 ABCOV-01, ALBERTA HOPE-Covid19, NCT04329611 Phase 3 Clinical Not yet recruiting 1 4 Months 1660 Carol C Kenney, RN, CCRP, Dr. L Metz, MD, Dr. M Hill, MD, Dr. Michael Hill, Luanne M Metz, MD, FRCPC, Luanne Metz, MD, Michael D Hill, MD, Michael D Hill, MD.FRCPC 2020-04-04
Hydroxychloroquine for COVID-19 PEP Coronavirus disease 19 infection, SARS coronavirus infection hydroxychloroquine sulfate alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Washington Bill & Melinda Gates Foundation, New York University US 2020-03-31 2020-10-31 NCT04328961, STUDY00009750 Phase 1 Clinical Not yet recruiting 0 7 Months 2000 Anna Bershteyn, PhD, Christine Johnston, MD, Helen Stankiewicz Karita, MD, Justice Quame-Amaglo, Kirsten Hauge, Meighan Krows, Ruanne V. Barnabas, MBChB, DPhil 2020-04-06
HAHPS: Hydroxychloroquine versus Azithromycin for Hospitalized Patients With Suspected or Confirmed COVID-19 Coronavirus disease 19 infection hydroxychloroquine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Intermountain Health Care Inc University of Utah US 2020-04-01 2021-12-31 1051355, HAHPS, NCT04329832 Phase 2 Clinical Not yet recruiting 0 21 Months 300 David P Tomer, MS, Estelle Harris, MD, Samuel M Brown, MD MS, Valerie T Aston, MBA, Valerie T Aston, MD MS 2020-04-06
COVID-19 During Pregnancy: a Prospective, Observational, Cohort Coronavirus disease 19 infection, Pregnancy disorder, SARS coronavirus infection Máxima Medical Center Netherlands 2020-03-27 2020-12-31 N20.035, NL8485 Phase Not Applicable Recruiting 1 9 Months 20 Marion Frenken 2020-04-03
A clinical trial of ALLTest Rapid Screen Antibody Test Cassette to evaluate the presence of the IgG and IgM antibodies to COVID-19 in whole blood, serum or plasma samples of COVID-19 patients Coronavirus disease 19 infection ALLTest Rapid Screen Antibody Test Cassette alone University of North Carolina Phase Not Applicable Status not specified 0 2020-04-02
A clinical study to detect COVID-19 using SeroFlash SARS-CoV-2 IgG/IgM Antibody Detection Kit Coronavirus disease 19 infection SeroFlash SARS-CoV-2 IgG/IgM Antibody Detection Kit alone Epigentek Group Inc Phase Not Applicable Status not specified 0 267 2020-04-02
ECMOCARD: ExtraCorporeal Membrane Oxygenation for 2019 novel Coronavirus Acute Respiratory Disease (COVID-19) Coronavirus disease 19 infection, Hypoxia, Respiratory disease ISARIC, Monash University, The Prince Charles Hospital Extracorporeal Life Support Organization US, Japan, Vietnam, Taiwan, Thailand, Australia, Singapore, South Korea, UK, Italy, Hong Kong, Indonesia 2020-03-05 2020-07-31 ACTRN12620000421932, ECMOCARD Phase Not Applicable Recruiting 18 4 Months 400 A / Prof Gianluigi Li Bassi, Prof John Fraser 2020-04-03
Mesenchymal Stem Cell therapy in COVID-19 Coronavirus disease 19 infection, Viral pneumonia conventional treatment alone, mesenchymal stem cells alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Bagheiat-allah University of Medical Sciences Iran 2020-03-28 2020-04-29 IR.BMSU.REC.1399.007, IRCT20200325046860N2 Phase 1 Clinical Recruiting 1 1 Month 5 Hasan Abolghasemi, Hasan abolghasemi 2020-04-03
ACORES-2: ACE Inhibitors or ARBs Discontinuation in Context of SARS-CoV-2 Pandemia Coronavirus disease 19 infection, SARS coronavirus infection discontinuation of RAS blocker therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris Hopital Universitaire de la Pitie Salpetriere France 2020-03-31 2020-05-31 ACORES-2, APHP200409, NCT04329195 Phase 3 Clinical Not yet recruiting 1 2 Months 554 Gilles MONTALESCOT, MD, PhD, Mathieu KERNEIS, MD 2020-04-03
COVID-19 in Patients With Pre-existing Cirrhosis (COVID-Cirrhosis-CHESS2002): A Multicenter, Observational Study Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hepatopancreatobiliary Surgery Institute of Gansu Province Affiliated Hospital of Jiangsu University, Ankang City Central Hospital, Dalian Sixth People's Hospital, Guangxi Zhuang Autonomous Region Guangxi, Hubei University for Nationalities, Hubei University of Medicine, LanZhou University, Lishui Central Hospital, Renmin Hospital of Wuhan University, The Central Hospital of Enshi Tujia And Miao Autonomous Prefecture, The Third People’s Hospital of Shenzhen, The sixth people's hospital of Shenyang, Tianjin Infectious Disease Hospital, Wuhan Union Hospital, China, XINGTAI PEOPLE HOSPITAL China 2020-03-30 2021-06-29 CHESS2002, NCT04329559 Phase Not Applicable Recruiting 15 15 Months 50 Bin Xiong, MD, Chuxiao Shao, MD, Dengxiang Liu, MD, Fengmei Wang, MD, Guo Zhang, MD, Hongguang Zhang, MD, Hongmei Yue, MD, Hua Yang, MD, Mingkai Chen, MD, Qing He, MD, Xiaodan Li, MD, Xiaolong Qi, Xiaolong Qi, MD, Yanna Liu, MD, Ye Gu, MD, Yong Zhang, MD, Zhengyan Wang, MD, Zicheng Jiang, MD 2020-04-03
SEB-COVID-19: SEB-COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Likas Malaysia 2020-04-01 2020-12-31 54437, NMRR-20-595-54437, SEB-COVID-19 Phase Not Applicable Not yet recruiting 1 9 Months Dr Cheah Phee Kheng 2020-04-03
PATCH: Prevention And Treatment of COVID-19 With Hydroxychloroquine Coronavirus disease 19 infection, Viral pneumonia Plaqeunil alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Pennsylvania US 2020-04-06 2021-12-01 842838, NCT04329923, PATCH Phase 2 Clinical Not yet recruiting 0 19 Months 400 Ravi Amaravadi, Ravi Amaravadi, MD 2020-04-06
A phase I trial of COVID-19 Vaccine, Ad26 SARS-CoV-2, for treatment of COVID-19 Coronavirus disease 19 infection Ad26 SARS-CoV-2 alone Johnson & Johnson Phase 1 Clinical Planned 0 2020-04-02
Impact of the Coronavirus (COVID-19) on Patients With Cancer Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Stanford University US 2020-04-30 2022-05-31 55596, NCT04330521 Phase Not Applicable Not yet recruiting 0 25 Months 50 Manali Indravadan Patel 2020-04-06
Evaluation of the performance of novel rapid diagnostics for COVID-19 at point-of-care Coronavirus disease 19 infection POC tests alone, standard PCR test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Heidelberg Germany 2020-04-05 DRKS00021220, S-180/2020 Phase Not Applicable Not yet recruiting 1 2000 Claudia Denkinger 2020-04-03
COVit: Improvement of the nutritional status regarding nicotinamide (vitamin B3) and the course of COVID-19 disease Coronavirus disease 19 infection nicotinamide alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitatsklinikum Schleswig-Holstein Campus Kiel Germany 2020-04-06 A 107/20, COVit, DRKS00021214 Phase Not Applicable Not yet recruiting 1 1300 Stefan Schreiber 2020-04-03
UKOSS: Pandemic COVID-19 in pregnancy Coronavirus disease 19 infection, Pregnancy disorder Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) University of Oxford National Institute for Health Research (NIHR) UK 2020-01-24 2022-12-31 CPMS 14162, IRAS 112935, ISRCTN40092247 Phase Not Applicable Recruiting 1 35 Months 500 Prof Knight 2020-04-06
COVIDENCE: Longitudinal. Population-based, Observational Study of Coronavirus Disease in the UK Population Coronavirus disease 19 infection, Viral pneumonia Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Queen Mary University of London King's College London, London School of Hygiene and Tropical Medicine UK 2020-04-02 2025-04-01 COVIDENCE, COVIDENCE, NCT04330599 Phase Not Applicable Not yet recruiting 1 60 Months 12000 Adrian Martineau, PhD, Hayley Holt, MSc 2020-04-06
Effects of High-dose Vitamin C on COVID-19 Coronavirus disease 19 infection standard treatment alone, vitamin C alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tehran University of Medical Sciences Iran 2020-04-03 IR.TUMS.VCR.REC.1399.056, IRCT20190917044805N2 Phase 2/Phase 3 Clinical Recruiting 1 60 Kourosh Sadeghi, Mohammad Ali Sahraian 2020-04-06
Effect of oral multi-herbal preparation on COVID-19 Coronavirus disease 19 infection routine treatment alone, capsule (dried extract of Hyssopus officinalis L., Punica granatum L.) plus decoction (Glycyrrhiza glabra L., Althaea officinalis L., Ziziphus jujuba Mill) Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Tehran University of Medical Sciences Iran 2020-03-23 IR.TUMS.VCR.REC.1399.024, IRCT20180712040449N2 Phase 3 Clinical Recruiting 3 68 Mehrdad Karimi, Mohammad Ali Sahraian, Samaneh Soleymani 2020-04-02
CORKUM: COVID-19 Registry of the LMU Hospital Munich Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Klinikum der Universitat Muenchen Germany 2020-04-02 20-245, CORKUM, DRKS00021225 Phase Not Applicable Not yet recruiting 1 1500 Johannes Hellmuth, Maximilian Münchhoff 2020-04-03
Efficacy and Safety of Siltuximab versus Corticosteroids in Hospitalized Patients With COVID19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia siltuximab alone Heat shock protein inhibitor, IL-6 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundacion Clinic per a la Recerca Biomédica Spain 2020-04-01 2020-05-20 NCT04329650, SILCOR-COVID-19 Phase 2 Clinical Not yet recruiting 2 1 Month 100 Alex Soriano, MD, Felipe García, MD, Judit Pich Martínez, Clinical Research Manager 2020-04-03
A Phase II Study to Assess The Effect of anti-Covid vaccine (coronavirus disease 19 infection), Federal Medical Biological Agency in the Treatment of Coronavirus disease 19 infection (Covid 19) Patient Coronavirus disease 19 infection prototype vaccine (coronavirus disease 19 infection), Federal Medical Biological Agency alone Federal Medical Biological Agency 2021-03-31 Phase 2 Clinical Planned 0 2020-04-03
A Phase I Study to Assess The Effect of anti-Covid vaccine (coronavirus disease 19 infection), Federal Medical Biological Agency in the Treatment of Coronavirus disease 19 infection (Covid 19) Patient Coronavirus disease 19 infection prototype vaccine (coronavirus disease 19 infection), Federal Medical Biological Agency alone Federal Medical Biological Agency 2020-12-31 Phase 1 Clinical Planned 0 2020-04-03
Understanding COVID Coronavirus disease 19 infection, SARS coronavirus infection sampling alone Hopitaux Universitaires De Geneve University of Geneva Switzerland 2020-03-27 2022-03-31 2020-00516, NCT04329546 Phase Not Applicable Recruiting 1 24 Months 250 Angela Huttner, MD, Claire-Anne Siegrist, MD 2020-04-03
TBA: A weapon against COVID-19: (Social) media and influencers Coronavirus disease 19 infection, SARS coronavirus infection social media and influencers alone Fred Foundation, Noaber Foundation Netherlands 2020-03-16 2020-03-29 METc VUmc 2020.141, NL8483, TBA Phase Not Applicable Recruiting 1 17000 Hamza Yousuf 2020-04-06
HB-MCO-Covid19: HB-MCO-Covid19 Coronavirus disease 19 infection National Institutes of Health Malaysia Malaysia 2020-04-01 2020-05-31 54511, HB-MCO-Covid19, NMRR-20-634-54511 Phase Not Applicable Status not specified 1 2 Months Norbaidurah binti Ithnain 2020-04-06
A clinical study to assess bucillamine in the treatment of subjects with COVID-19 infection Coronavirus disease 19 infection repurposed formulation of bucillamine (gout/cystinuria/Wilson disease), Revive Therapeutics alone Xanthine oxidase inhibitor Revive Therapeutics Ltd Japan, South Korea Phase Not Applicable Planned 2 2020-04-02
Psychological effects of coronavirus disease 2019 (covid-19) amongst healthcare workers Coronavirus disease 19 infection, Psychiatric disorder National Institutes of Health Malaysia Malaysia 2020-04-01 2020-05-31 54488, NMRR-20-633-54488 Phase Not Applicable Status not specified 1 2 Months Mr Kamarul Zaman bin Salleh 2020-04-02
Phase III Clinical Study of Favipiravir in Patients with COVID-19 Non-Severe Pneumonia Coronavirus disease 19 infection, Viral pneumonia favipiravir alone RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) FUJIFILM Toyama Chemical Co Ltd Japan 2020-03-31 2020-06-30 JapicCTI-205238 Phase 3 Clinical Recruiting 1 3 Months 96 2020-04-02
BCG-CORONA: Reducing Health Care Workers Absenteeism in Covid-19 Pandemic Through BCG Vaccine Coronavirus disease 19 infection, SARS coronavirus infection Bacillus Calmette-Guerin vaccine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitair Medisch Centrum Utrecht Radboud University Netherlands 2020-03-25 2020-12-25 BCG-CORONA, NCT04328441, NL73249.041.20, NL8477 Phase 3 Clinical Recruiting 9 9 Months 1500 Andreas Voss, MD, PhD, Angele Kerckhoffs, MD, PhD, Anna Roukens, MD, PhD, Bart Rijnders, MD, PhD, Jaap den Oever, MD, PhD, Karin Veerman, MD, Kees van Nieuwkoop, MD, PhD, MJM Bonten, Thijs ten Doesschate, MD, Thomas van der Vaart, MD, Wim Boersma, MD, PhD 2020-04-06
Clinical Characteristics and Prognostic Factors of Patients With COVID-19 Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shanghai 10th People's Hospital Chibi People's Hospital China 2020-01-30 2020-04-15 HBCBH-IEC-2020-101, NCT04328454 Phase Not Applicable Recruiting 1 2 Months 120 Ming Li, Ming Li, M.D. 2020-04-02
Prevention of COVID-19 infection in a medical institution and maintenance of medical system Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Jichi Medical School Japan 2020-04-01 UMIN000039997 Phase Not Applicable Not yet recruiting 1 3700 Hironori Yamamoto 2020-04-02
A clinical study of BOLD-100 in the treatment in patients of COVID-19 infection Coronavirus disease 19 infection IT-139 alone Grp78 calcium binding protein inhibitor, Jun N terminal kinase inhibitor, Transferrin modulator, p38 MAP kinase modulator Bold Therapeutics Inc Phase Not Applicable Planned 0 2020-04-02
A study of hydroxychloroquine for the treatment of patients with COVID-19 Coronavirus disease 19 infection hydroxychloroquine alone Sandoz International GmbH, US Department of Health and Human Services US Phase Not Applicable Planned 0 2020-04-02
A phase I clinical study to assess immunogenicity of single-dose, intranasal AdCOVID in the treatment of COVID-19 Coronavirus disease 19 infection AdCOVID alone Altimmune Inc University of Alabama at Birmingham 2020-09-30 Phase 1 Clinical Planned 0 2020-04-06
CRONOS: COVID-19 related obstetric and neonatal outcome study Coronavirus disease 19 infection Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Deutschen Gesellschaft für Perinatale Medizin e.V.c/o Conventus Congressmanagement & Marketing GmbH Germany 2020-04-01 CRONOS, D 451/20, DRKS00021208 Phase Not Applicable Not yet recruiting 1 100 Ulrich Pecks 2020-04-03
A compassionate use program to assess PLX cell therapy in the treatment of patients with coronavirus infection (COVID-19) Coronavirus disease 19 infection PLX stem cell therapy, Pluristem/Cha Bio & Diostech alone IL-6 receptor agonist Pluristem Therapeutics Inc Charite University Phase Not Applicable Recruiting 0 2020-04-02
Phase II clinical trial of antroquinonol to treat Covid-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia antroquinonol alone MEK-1 protein kinase inhibitor, Ras gene inhibitor Golden Biotechnology Corp Phase 2 Clinical Planned 0 2020-04-02
COVID-19-HBO: Safety and Efficacy of Hyperbaric Oxygen for ARDS in Patients With COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome hyperbaric oxygen alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Karolinska University Hospital Blekingesjukhuset, Karlskrona, Karolinska Institutet, University of California San Diego Sweden 2020-04-25 2022-12-31 2020-001349-37, 4-1199/2020, COVID-19-HBO, K-2020-2611, NCT04327505 Phase 2/Phase 3 Clinical Not yet recruiting 1 32 Months 200 Anders Kjellberg, MD, Peter Lindholm, MD, PhD 2020-04-02
CODEX: COVID-19-associated ARDS Treated With Dexamethasone: Alliance Covid-19 Brasil III Adult respiratory distress syndrome, Coronavirus disease 19 infection dexamethasone alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sociedade Beneficiente De Senhoras Hospital Sirio Libanes Ache Laboratorios Farmaceuticos SA, Brazilian Research In Intensive Care Network, Hospital do Coracao, Sociedade Beneficente Israelita Brasileira Hospital Albert Einsten Brazil 2020-04-01 2020-08-30 CODEX, CODEX_V1.1, NCT04327401 Phase 3 Clinical Not yet recruiting 21 4 Months 290 Adrian PM Kormann, MD, Bruno M Tomazini, MD, Bruno Tomazini, M.D, Carla MG Godoy, MD, Cintia MC Grion, MD, Cristina P Amendola, MD, Eduardo LV Costa, PhD, Eraldo A Lucio, MD, Felipe Dal Pizzol, MD, Fernando C Neuenschwander, MD, Fernando G Zampieri, MD, Flavia R Machado, MD, Frederico C DallOrto, MD, Israel S Maia, MD, Jorge LR Paranhos, MD, Luciano CP Azevedo, PhD, Luciano Cesar Pontes Azevedo, Ph.D, Luiz F. L. Reis, Ph.D., Marco AV Guedes, MD, Maria SM Paiva, MD, Mauro E Hernandes, MD, Otávio Berwanger, PhD, Rodrigo C Figueiredo, MD, Rodrigo S Biondi, MD, Viviane C Veiga, MD, Wilson J Lovato, MD 2020-04-02
A medical records based study for safety and effectiveness analysis of data from novel coronavirus pneumonia (COVID-19) patients with conventional therapy Coronavirus disease 19 infection, Viral pneumonia chloroquine plus hydroxychloroquine Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Peking University Third Hospital China 2020-03-28 2020-05-29 ChiCTR2000031376 Phase Not Applicable Recruiting 1 2 Months 600 Chunyang Wang, Dongyang Liu 2020-04-06
A Longitudinal Study of SARS-CoV-2 Positive Patients Testing Nasal Swabs and Collecting Blood Samples for Research Coronavirus disease 19 infection, SARS coronavirus infection Foam nasal swabs alone, Polyester nasal swabs alone UnitedHealth Group Inc Bill & Melinda Gates Foundation, Mayo Clinic Foundation, PATH (US) US 2020-03-25 2020-04-10 20-002, NCT04327804 Phase Not Applicable Recruiting 0 120 Ethan Berke, Yuan Po Tu, MD, Yuan Tu 2020-04-02
The Use of Focused Lung Ultrasound in Patients Suspected of COVID-19 Coronavirus disease 19 infection, Respiratory failure focused lung ultrasound alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Aarhus University Denmark 2020-03-14 2020-05-15 COVID-FLUS, NCT04327674 Phase Not Applicable Recruiting 2 2 Months 375 Jesper Weile, Søren H Skaarup, Søren Helbo SH Skaarup, MD 2020-04-02
Mindfulness During COVID-19 Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection Mindfulness session(s) alone Healthy volunteers accepted Wake Forest University Health Sciences, US US 2020-03-31 2020-12-31 IRB00064587, NCT04319445 Phase Not Applicable Not yet recruiting 0 9 Months 200 Rebecca E Wells, MD, MPH 2020-04-02
COV19-PLASMA: Hyperimmune Plasma for Critical Patients With COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome, SARS coronavirus infection hyperimmune plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fondazione IRCCS Policlinico San Matteo ASST Cremona, Carlo Poma Hospital, Lodi Hospital Italy 2020-03-17 2020-05-31 COV19-PLASMA, IRCCSSANMATTEOH, NCT04321421 Phase 2 Clinical No longer recruiting 1 2 Months 49 Cesare Perotti, MD 2020-04-02
PROACTIVE-19: Personalized Health Education Against the Health Damage of Novel Coronavirus (COVID-19) Outbreak in Hungary Coronavirus disease 19 infection, Heart arrhythmia, Respiratory distress syndrome, Shock Personalized health education alone Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Of Pécs Hungary 2020-04-01 2021-08-21 IV/2428- 2 /2020/EKU, NCT04321928, PROACTIVE-19 Phase Not Applicable Not yet recruiting 1 16 Months 7576 Bálint Erőss, MD, Péter Hegyi, MD, PhD, DSc 2020-04-02
DISPOSE: DIgital Online SuPport for COVID-19 StrEss Acute stress disorder, Coronavirus disease 19 infection, Depression, Generalized anxiety disorder Guided online support program alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) International Psychoanalytic University Selfapy GmbH Germany 2020-03-31 2021-12-31 DISPOSE, IPUB_2020_01, NCT04324190 Phase Not Applicable Not yet recruiting 1 21 Months 600 Gunther Meinlschmidt, Prof. Dr., Kati Bermbach 2020-04-02
Covid: Effectiveness of Hydroxychloroquine in Covid-19 Patients Coronavirus disease 19 infection, Viral pneumonia hydroxychloroquine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Ayub Medical College Pakistan 2020-03-28 2020-06-28 ATH/CT101/22/3, Covid, NCT04328272 Phase 3 Clinical Not yet recruiting 2 3 Months 75 Muhammad J Khan, MBBS, Prof. Dr. Umar Farooq, Dean, Umar Farooq, PhD, Umer Farooq, PhD 2020-04-06
Evaluation of Covid 19 Knowledge Anxiety and Expectation Levels of Turkish Physicians, Survey Study Anxiety disorder, Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Istanbul Bakirkoy Maternity and Children Diseases Hospital Turkey 2020-03-26 2020-04-28 NCT04327531, TURKISHCOVID19 Phase Not Applicable No longer recruiting 1 1 Month 200 Pınar Yalcin bahat 2020-04-03
COVID-19 Rapid Test Kit Use in Screening Center Coronavirus disease 19 infection COVID-19 IgG/IgM Rapid Test kit alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sabah Women and Children's Hospital Malaysia 2020-04-10 2020-09-30 NMRR-20-640-54491 Phase Not Applicable Not yet recruiting 1 5 Months Darlene Flavius Ongkili, Dr Cheah Phee Kheng 2020-04-02
CORONA: Hydroxy Chloroquine, in open-labelled, Randomized intervention for prevention of new infection and adverse outcomes following COVID-19 infection -A Tertiary Hospital based study Coronavirus disease 19 infection hydroxychloroquine sulphate alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Aster Malabar Institute of Medical Sciences India 2020-04-08 CORONA, CTRI/2020/03/024402 Phase 3 Clinical Not yet recruiting 1 500 Dr Remesh Bhasi 2020-04-02
COVID MED: Comparison Of Therapeutics For Hospitalized Patients Infected With SARS-CoV-2 In A Pragmatic Adaptive Randomized Clinical Trial During The COVID-19 Pandemic Coronavirus disease 19 infection, SARS coronavirus infection hydroxychloroquine sulfate alone, lopinavir + ritonavir alone, losartan alone, standard care alone Angiotensin II AT-1 receptor antagonist, Angiotensin II receptor antagonist, HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bassett Healthcare US 2020-04-01 2021-04-01 1581969, COVID MED, NCT04328012 Phase 2/Phase 3 Clinical Not yet recruiting 0 12 Months 4000 Daniel Freilich, MD, Jennifer Victory, RN, daniel Freilich, MD 2020-04-02
Study for the changes of the brain structure and function in healed patients of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia functional magnetic resonance imaging technology alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Union Hospital Tongji Medical School Huazhong University Of Science & Technology China 2020-04-01 2021-04-04 ChiCTR2000031356 Phase Not Applicable Not yet recruiting 1 12 Months 600 Wenliang Fan 2020-04-02
COVIDAXIS: Chemoprophylaxis of SARS-CoV-2 Infection (COVID-19) in Exposed Healthcare Workers Coronavirus disease 19 infection, SARS coronavirus infection hydroxychloroquine alone, lopinavir + ritonavir alone HIV protease inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire de Saint Etienne Institut Pasteur France 2020-03-30 2020-11-30 2020-001188-96, 20PH061, COVIDAXIS, NCT04328285 Phase 3 Clinical Not yet recruiting 3 8 Months 1200 Amandine GAGNEUX-BRUNON, Arnauld Garcin, Bernard TARDY, Bruno Hoen, MD, PhD, Elisabeth BOTELHO-NEVERS, Elisabeth Botelho-Nevers, MD, PhD, Isabelle PELLIER, Marc-Antoine CUSTAUD, Nathalie Jolly, Sandrine ACCASSAT, Vincent DUBEE, Xavier DUVAL 2020-04-02
A phase I clinical treatment to evaluate the safety and efficacy of COVID-19 vaccine for the potential prevention of coronavirus infection COVID-19 Coronavirus disease 19 infection SARS-CoV-2 recombinant adenoviral vector vaccine (AdVac/PER.C6, COVID-19), Johnson & Johnson/Biomedical Advanced Research and Development Authority/Beth Israel Deaconess Medical Center alone Beth Israel Deaconess Medical Center, Johnson & Johnson 2020-09-30 Phase 1 Clinical Planned 0 2020-04-02
COVID-19 HOPE Trial: Heparin-N-acetylcysteine in COVID-19 Patients by Evaluation of Pulmonary Function Coronavirus disease 19 infection N-acetylcysteine plus heparin Atossa Genetics Inc COVID-19 HOPE Trial Phase Not Applicable Not yet recruiting 0 Dr Steven Quay 2020-04-02
A clinical study of CytoSorb for the treatment of in patients infected with COVID-19 Coronavirus disease 19 infection CytoSorb alone CytoSorbents Corp Phase Not Applicable Status not specified 0 2020-04-06
Causes of fever in outpatient outside Wuhan during novel coronavirus pneumonia pandemic: a medical records based retrospective analysis Coronavirus disease 19 infection, Fever, Influenza virus infection medical records based analysis alone Chinese PLA General Hospital China 2020-04-01 2020-05-31 ChiCTR2000031366 Phase Not Applicable Not yet recruiting 1 2 Months 5000 Bin Liu, Kun Xiao 2020-04-02
BRACE: BCG Vaccination to Protect Healthcare Workers Against COVID-19 Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia BCG vaccine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Murdoch Childrens Research Institute Royal Childrens Hospital, Melbourne Australia 2020-03-30 2022-03-30 62586, BRACE, NCT04327206 Phase 3 Clinical Recruiting 2 24 Months 4170 Kaya Gardiner, Prof Nigel Curtis, Prof Nigel Curtis, MBBS PhD 2020-04-03
To explore the pathogenesis and course prediction of novel coronavirus pneumonia (COVID-19) severe patients Coronavirus disease 19 infection, Viral pneumonia LC-MS-based metabolomic analysis alone, TMT-based quantitative proteomics alone Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Westlake University China ChiCTR2000031365 Phase 0 Clinical Recruiting 1 Bo Shen, Haixiao Chen 2020-04-02
COLCOVID: The ECLA PHRI COLCOVID Trial Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia colchicine alone, local standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Estudios Clinicos Latino America Population Health and Research Institute, Trivandrum, Kerala, india 2020-03-31 2020-06-30 COLCOVID, COLCOVID VERSION1.2, NCT04328480 Phase 3 Clinical Not yet recruiting 0 3 Months 2500 Andres Orlandini, MD, Rafael Diaz, MD 2020-04-02
TPB-COVID-19 Coronavirus disease 19 infection National Institutes of Health Malaysia Ministry of Health, Malaysia Malaysia 2020-04-01 2020-06-30 54505, NMRR-20-632-54505 Phase Not Applicable Not yet recruiting 1 3 Months MUHAMMAD RIDZWAN BIN ZAKARIA 2020-04-03
VICO: The Vietnam Chloroquine Treatment on COVID-19 Coronavirus disease 19 infection, SARS coronavirus infection chloroquine phosphate alone, standard of care therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Oxford University Clinical Research Unit, Vietnam Can Gio COVID Hospital, Cho Ray Hospital, Cu Chi COVID Hospital, Department of Health, Ho Chi Minh city, Ministry of Health and Welfare, Vietnam, National Institute for Infectious And Tropical Diseases, The Hospital for Tropical Diseases Vietnam 2020-04-01 2022-04-01 COVID, NCT04328493, VICO Phase 2 Clinical Not yet recruiting 5 24 Months 250 Dung Nguyen, PhD. MD, Guy Thwaites, PhD. MD, Hung Le Quoc, MD, Jeremy Day, PhD. MD, Manh Hung Le, Nguyen Huy Man Dinh, Dr, Phuong Thao Huynh, Phar, Thach N Pham, PhD. MD, Thach N Pham, PhD.MD, Thanh Dung Nguyen, Thanh Dung Nguyen, Dr, Thanh Phong Nguyen, Dr, Thanh Truong Nguyen, Dr, Van Vinh Chau Nguyen, Dr, Van Vinh Chau Nguyen, PhD, MD 2020-04-03
Audio Data Collection for Identification and Classification of Coughing Allergic rhinitis, Asthma, Chronic obstructive pulmonary disease, Common cold, Coronavirus disease 19 infection, Coronavirus infection, Cough, Influenza virus infection, Respiratory tract infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) HealthMode Inc. US 2020-03-25 2022-09-25 HM070102, NCT04326309 Phase Not Applicable Recruiting 0 30 Months 1000 Daniel R Karlin, MD, MA 2020-04-02
COntAGIouS: In-depth Immunological Investigation of COVID-19 Coronavirus disease 19 infection, SARS coronavirus infection Patient sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitaire Ziekenhuizen Leuven 2020-03-27 2020-09-30 CONTAGIOUS, COntAGIouS, NCT04327570 Phase Not Applicable Not yet recruiting 0 6 Months 100 Joost Wauters, MD PhD 2020-04-02
A randomized trial to evaluate the effectiveness and safety of COVID-19 convalescent plasma for both treatment of COVID-19 positive patients at all stages of disease progression as well as prevention of infection after high-risk exposure Coronavirus disease 19 infection COVID-19 convalescent plasma alone Healthy volunteers accepted Johns Hopkins University Albert Einstein College of Medicine, Bloomberg Philanthropies, Mayo Clinic, Minnesota, Stanford University Medical Center US Phase Not Applicable Planned 0 Arturo Casadevall 2020-04-02
A Phase I/II safety trial of ST-266 for Treatment of the Severe Inflammatory Response Associated with COVID-19 Coronavirus disease 19 infection ST-266 alone Noveome Biotherapeutics Inc Phase 1/Phase 2 Clinical Planned 0 2020-04-02
Characterization of Cardiovascular Diseases and Risk Factors in Patients With Suspected SARS-CoV2/Covid-19 Infection Cardiovascular disease, Coronavirus disease 19 infection, SARS coronavirus infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitatsklinikum Essen Germany 2020-03-26 2026-03-25 20-9213-BO, NCT04327479 Phase Not Applicable Recruiting 1 72 Months 6000 Amir A Mahabadi, MD, Matthias Totzeck, MD, Tienush Rassaf, MD 2020-04-03
Pre-exposure Prophylaxis for SARS-coronavirus-2 Coronavirus disease 19 infection, SARS coronavirus infection hydroxychloroquine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Minnesota US 2020-04-01 2020-08-31 NCT04328467, RAJASINGHAM Phase 3 Clinical Not yet recruiting 0 5 Months 3500 Radha Rajasingham (Please Email), MD, Radha Rajasingham, MD, Sarah Lofgren 2020-04-04
Antivirals for COVID-19: Covid-19: A randomized, open-label, adaptive, proof-of-concept clinical trial of new antiviral drug candidates against SARS-CoV-2 Coronavirus disease 19 infection itraconazole alone Lanosterol-14 demethylase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) UZ Leuven-University Hospitals Belgium 2020-04-26 2020-001243-15, Antivirals for COVID-19, S63874 Phase 2 Clinical No longer recruiting 1 200 Laurens Liesenborghs 2020-04-02
N-ReCOVID 19: A clinical study to evaluate the efficacy of different anti-viral drugs in SARS-CoV-2 infected patients (COVID-19) Coronavirus disease 19 infection Plaquenil plus remdesivir RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Oslo University Hospital Norway 2020-03-26 2020-000982-18, N-ReCOVID 19, WHO-NOR-COVID-19 Phase 3 Clinical No longer recruiting 1 443 Sect. Clin. Imm. & Infect. Diseases 2020-04-02
A medical records based study for novel coronavirus pneumonia (COVID-19) patients undergoing endotracheal intubation Coronavirus disease 19 infection, Viral pneumonia endotracheal intubation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tongji Hospital, Huazhong University of Science and Technology China 2020-02-04 2020-03-12 ChiCTR2000031439 Phase Not Applicable No longer recruiting 1 1 Month 59 Hongbo Zheng, Li Wan 2020-04-03
The Effects of novel coronavirus pneumonia (COVID-19) Risk Factors on Dynamic Changes of Immunological, biochemical, and Metabolic Parameters: a Retrospective, Observational Study Coronavirus disease 19 infection, Viral pneumonia Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tongji Hospital, Huazhong University of Science and Technology China 2020-04-01 2021-03-31 ChiCTR2000031429 Phase Not Applicable Not yet recruiting 1 12 Months 2000 Ji-Xin Zhong, Lingli Dong 2020-04-03
Novel coronavirus infection (COVID-19) IgM detection kit (magnetic particle chemiluminescence) clinical trial Coronavirus disease 19 infection First People's Hospital of Jiangxia District, Wuhan (Union Jiangnan Hospital) Taizhou Zecheng Biotechnology Co. Ltd. China 2020-03-01 2020-03-25 ChiCTR2000031427 Phase 0 Clinical Not yet recruiting 1 200 Pang Jifeng, Xiang Changgang 2020-04-02
COVID-19-FR: COVID-19 Registry Freiburg Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Heart Centre Freiburg-Bad Krozingen Germany 2020-03-26 153/20, COVID-19-FR, DRKS00021206 Phase Not Applicable Recruiting 1 400 Achim Lother, Mr. Prof. Dr. Daniel Dürschmied 2020-04-02
Clinical application value of multiple tests for novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Wuhan Asia Heart Hospital China 2020-02-05 2020-10-04 ChiCTR2000031428 Phase Not Applicable No longer recruiting 1 8 Months 500 Qingkun Fan, Zejin Liu 2020-04-02
Clinical study of human umbilical cord mesenchymal stem cells in the treatment of novel coronavirus pneumonia (COVID-19) induced pulmonary fibrosis Coronavirus disease 19 infection, Pulmonary fibrosis, Viral pneumonia Conventional treatment regimen alone, human umbilical cord mesenchymal stem cells alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) 302 Military Hospital of China China 2020-03-14 2021-12-31 ChiCTR2000031430 Phase 2 Clinical Recruiting 4 21 Months 200 Fu-Sheng Wang, Lei Shi 2020-04-03
A single center clinical study of evaluating the injection of microRNA2911 plasmid in healthy adults Coronavirus disease 19 infection, Viral pneumonia microRNA2911 plasmid alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Nanjing Drum Tower Hospital, Nanjing University China 2020-04-01 2020-08-31 ChiCTR2000031432 Phase 1 Clinical Not yet recruiting 1 5 Months 15 Chenyu Zhang, Yanbo Wang 2020-04-06
Treating COVID-19 With a Bidirectional Oxygenation Valve Coronavirus disease 19 infection bidirectional oxygenation mouthpiece alone, non-rebreather face mask alone, oxygen alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) TMC HealthCare PEEP Medical, LLC US 2020-03-27 2020-06-01 COVID19PEEP2020, GO2 PEEP Study, NCT04326452 Phase Not Applicable Recruiting 0 2 Months 15 Ashvinder Khanna, MD, Jeffrey Miller, MD, Joseph Levitt, MD, Matthew Weiner, MD, Natalia Elias Calles, MPH, Sonya Mathewson, RN 2020-04-02
PREDICT: Prediction of Diagnosed Covid-19 Infection in IUC Patients Coronavirus disease 19 infection, Respiratory tract infection PCR alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Regional Universitaire de Lille France 2020-03-30 2021-09-30 2020-A00763-36, 2020_20, NCT04327180, PREDICT Phase Not Applicable Recruiting 1 18 Months 500 Julien Goutay, MD, Julien Poissy, MD,PhD, Martine Remy-Jardin, MD,PhD, Morgan Caplan, MD, Philippe Mathurin, MD,PhD, Sophie Susen, MD,PhD 2020-04-03
Efficacy of Tumor Necrosis Factor-Alpha Inhibitor in COVID-19 Coronavirus disease 19 infection, SARS coronavirus infection Variable regimens including etanercept biosimilar, AryoGen , hydroxychloroquine , lopinavir + ritonavir HIV protease inhibitor, TNF antagonist, TNF binding agent, Type II TNF receptor modulator Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tehran University of Medical Sciences Iran 2020-03-27 IR.TUMS.VCR.REC.1399.034, IRCT20200312046749N1 Phase 2/Phase 3 Clinical Recruiting 1 80 Mohammad Ali Sahraian, Raheleh Assari, Vahid Ziaee 2020-04-02
GARM-COVID19: Use of cSVF Via IV Deployment for Residual Lung Damage After Symptomatic COVID-19 Infection Chronic obstructive pulmonary disease, Coronavirus disease 19 infection, Lung disease, Respiratory distress syndrome Centricyte 1000 (Healeon Medical) alone, Microcannula Closed System (Tulip Med) alone, autologous cellular stromal vascular fraction alone, lipoaspiration alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) HEALEON MEDICAL INC Robert W. Alexander, MD US 2020-03-25 2021-12-31 GARM COVID19, GARM-COVID19, NCT04326036 Phase 0 Clinical Recruiting 0 21 Months 10 Robert W Alexander, MD 2020-04-02
EC-COVID-RCT: Early CPAP in COVID Patients With Respiratory Failure Coronavirus disease 19 infection, Respiratory failure continuous positive airway pressure ventilation alone, current clinical practice alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Istituto di Ricerche Farmacologiche Mario Negri Italy 2020-04-06 2020-11-09 EC-COVID-RCT, EC-COVID-RCT-FENICE, NCT04326075 Phase Not Applicable Not yet recruiting 1 7 Months 900 Elena Garbero, M.Sc., Guido Bertolini, MD 2020-04-02
Coronavirus Disease 2019 (COVID-19) Study of Hospitalized Patients in Hong Kong Coronavirus disease 19 infection, Viral pneumonia laboratory monitoring alone, nasopharyngeal aspiration alone, sputum collection alone, swab flocking alone, tracheal aspiration alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chinese University of Hong Kong Hong Kong 2020-02-24 2021-06-17 COVID-19 STUDY 2020.076, NCT04325919 Phase Not Applicable Recruiting 1 15 Months 170 Paul CHAN, Paul KS Chan 2020-04-03
Early PP With HFNC Versus HFNC in COVID-19 Induced Moderate to Severe ARDS Coronavirus disease 19 infection, Respiratory distress syndrome Prone positioning alone, high flow nasal cannula alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rush University Medical Center Medical College of Wisconsin US 2020-04-06 2020-06-30 COVID-19-HFNC+PP, NCT04325906 Phase Not Applicable Not yet recruiting 0 2 Months 346 David Vines, PhD, Jennifer Peterson, PhD, Jie Li, PhD, Kellianne Fleming, MS, Rahul Nanchal, MD, Sara Mirza, MD, Victoria Arinta, MS 2020-04-04
Psychological distress of the COVID-19 pandemic: A comparison between cancer patients and healthy controls Anxiety disorder, Coronavirus disease 19 infection, Depression Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Klinik fur Psychosomatische Medizin und Psychotherapie, Univeristat Duisburg-Essen Germany 2020-03-16 19-8834-BO, DRKS00021164 Phase Not Applicable Recruiting 1 220 Venja Musche 2020-04-02
COVIDx: Evaluation of Novel Diagnostic Tests for 2019-nCOV Coronavirus disease 19 infection CT scan alone, SAMBA II device alone, chest X-ray alone, polymerase chain reaction alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cambridge University Hospitals NHS Foundation Trust UK 2020-04-08 2021-10-07 COVIDX, COVIDx, NCT04326387 Phase Not Applicable Not yet recruiting 1 18 Months 200 Anne-Laure Vallier, PhD., Ravindra Prof. Gupta, BMBCh, Richard D. Skells, BSc. 2020-04-01
Effectiveness and Safety of Respiratory Training in the Prevention and Severity of COVID-19 Coronavirus disease 19 infection Power-breath device alone, Winner-flow device alone, expiratory training alone, inspiratory training alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidad Complutense de Madrid Spain 2020-04-26 2020-10-12 COVID_ISCIII 20/265-E_BS, NCT04326114 Phase Not Applicable Not yet recruiting 1 5 Months 240 César Calvo Lobo, César Calvo Lobo, PhD 2020-03-31
GRECCO-19: The GReek Study in the Effects of Colchicine in COVID-19 complications prevention Coronavirus disease 19 infection, Myocardial infarction, SARS coronavirus infection, Viral pneumonia Colchicine alone, Standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) ELPEN Pharmaceutical Co Inc, Hellenic Society of Rhythmology, National and Kapodistrian University of Athens Greece 2020-04-06 2020-09-30 2020-001455-40, 906295542, GRECCO-19, NCT04326790 Phase 2 Clinical Recruiting 1 5 Months 180 Hellenic Society of Rhythmology, Spyridon Deftereos 2020-04-06
CoV-Ak-Test: Development of a test to measure the immune response in patients with Covid-19 Coronavirus disease 19 infection, SARS coronavirus infection SARS-CoV-2 antibody ELISA alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institut für Virologie, Universitätsklinikum Leipzig Germany 2020-03-30 124/20-ek, CoV-Ak-Test, DRKS00021166 Phase Not Applicable Not yet recruiting 1 15 Christian Jassoy 2020-04-02
Clinical study of recombinant protein subunit vaccine (COVID-19) Coronavirus disease 19 infection recombinant protein subunit vaccine (COVID-19), SK Bioscience alone SK Bioscience 2020-09-30 Phase Not Applicable Planned 0 2020-04-02
A Phase I Study to Assess the Effect of Gimsilumab in The Treatment of COVID-19 Associated With Acute Respiratory Distress Syndrome (ARDS) Patients Coronavirus disease 19 infection, Respiratory distress syndrome gimsilumab alone GM-CSF ligand inhibitor Altasciences Company Inc, Roivant Sciences Ltd 2020-03-27 Phase 1 Clinical Completed 0 2020-03-31
Clinical Trial of renin-angiotensin-aldosterone system inhibitors with halting their administration and the effect on clinical outcomes of patients with corona virus disease-2019 (COVID-19) referring to Sina Hospital in 2020 Coronavirus disease 19 infection, Viral pneumonia beta-blocker therapy alone, calcium channel blocker therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tehran University of Medical Sciences Iran 2020-04-05 IR.TUMS.VCR.REC.1399.028, IRCT20151113025025N3 Phase 4 Clinical Recruiting 1 60 Maryam Bahreini, Mohammad Ali Sahraian 2020-04-06
Convalescent Plasma therapy for COVID-19 Patients Coronavirus disease 19 infection convalescent plasma alone, current treatment alone Darman Ara, Iran Blood Transfusion Organization Iran 2020-03-15 IR.BMSU.REC.1398.434, IR.TMI.REC.1398.031, IRCT20200325046860N1 Phase 2 Clinical Recruiting 4 200 Abbas Ali Imani Fooladi, Dr Ehsan Sharifipour, Dr Hassan Abolghasemi, Dr Masoud Reza Sohrabi, Dr. Payam Tabarsi, Hassan Abolghasemi 2020-04-02
The effect of naproxen on the healing process of patients with COVID-19 Coronavirus disease 19 infection, Viral pneumonia Variable regimens including chloroquine phosphate , hydroxychloroquine sulfate , lopinavir + ritonavir , naproxen HIV protease inhibitor Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Abadan School of Medical Sciences Iran 2020-03-28 IR.ABADANUMS.REC.1398.115, IRCT20200324046850N3 Phase 3 Clinical Recruiting 1 40 Sara Mobarak 2020-04-02
Effect of Benson Relaxation on Quality of Life and job stress in nurses Acute stress disorder, Coronavirus disease 19 infection Benson relaxation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Sabzevar University of Medical Sciences Iran 2020-02-28 IR.MEDSAB.REC.1398.141, IRCT20131113015393N6 Phase Not Applicable Recruiting 1 62 Ali Taj Abadi, Narjes Heshmati Far, Narjes Heshmatifar 2020-04-02
Active Monitoring And Determinants of Incidence Infection of COVID-19 Coronavirus disease 19 infection, SARS coronavirus infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundacion Teofilo Hernando Spain 2020-03-23 2020-09-20 AMADIICH, NCT04326400 Phase Not Applicable Recruiting 1 5 Months 1000 Artuto García, Joan Soriano, MD, PhD, Marcos Maroto 2020-04-02
A single-center, open-label, randomized, and controlled trial of darunavir and cobicistat (DRV/c) in treating laboratory-confirmed COVID-19 patients Coronavirus disease 19 infection darunavir + cobicistat (fixed dose, HIV infection), Janssen R&D/ Gilead alone Cytochrome P450 3 inhibitor, HIV-1 protease inhibitor Johnson & Johnson China Phase 2 Clinical Status not specified 1 30 2020-03-31
Effect of metformin in COVID-19 mortality rate and symptom improvement Coronavirus disease 19 infection, Viral pneumonia metformin hydrochloride alone, standard regimen therapy alone AMP activated protein kinase stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tabriz University of Medical Sciences Iran 2020-03-20 IR.TBZMED.REC.1398.1310, IRCT20160310026998N11 Phase 3 Clinical Recruiting 1 200 Saba Ghaffary 2020-04-06
Effect of vitamin A in patients with COVID-19 Coronavirus disease 19 infection vitamin A alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tabriz University of Medical Sciences Iran 2020-04-03 IR.TBZMED.REC.1398.1305, IRCT20170117032004N3 Phase 2 Clinical Recruiting 1 30 Dr. Mohammad Sameiee, Zeinab Niknaiz, Zeinab Nikniaz 2020-04-06
Sarilumab COVID-19 Coronavirus disease 19 infection, Viral pneumonia sarilumab alone, supportive care alone IL-6 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sanofi SA, Sanofi-Aventis Research and Development Regeneron Pharmaceuticals Inc Canada, Russian Federation, Spain, Italy, France, Germany 2020-03-28 2021-06-30 2020-001162-12, EFC16844, NCT04327388, U1111-1249-6021 Phase 2/Phase 3 Clinical Recruiting 7 15 Months 300 Clinical Sciences & Operations 2020-04-03
Proflaxis Using Hydroxychloroquine Plus Vitamins-Zinc During COVID-19 Pandemia Coronavirus disease 19 infection Variable regimens including Plaquenil , vitamin A , vitamin C , vitamin D , zinc Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Istinye Universitesi Turkey 2020-03-20 2020-09-01 2020-2/1, NCT04326725 Phase Not Applicable Recruiting 1 5 Months 80 Istinye University M ozmen, Prof, Mahir M Ozmen, Professor, Mehmet Mahir Ozmen 2020-04-01
COVIDL1: A Study to Investigate the Efficacy of Tradipitant in Treating Severe or Critical COVID-19 Infection Coronavirus disease 19 infection, Lung injury tradipitant alone NK1 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Vanda Pharmaceuticals Inc 2020-04-01 2020-08-31 COVIDL1, NCT04326426, VLY-686-3501 Phase 3 Clinical Not yet recruiting 0 5 Months 300 Vasilios Polymeropoulos, MD 2020-04-01
HYCOVID: Hydroxychloroquine Versus Placebo in Patients Presenting COVID-19 Infection and at Risk of Secondary Complication: a Prospective, Multicenter, Randomized, Double-blind Study Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia hydroxychloroquine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Angers 2020-04-30 2020-09-30 49RC20_0071, HYCOVID, NCT04325893 Phase 3 Clinical Not yet recruiting 0 5 Months 1300 Béatrice GABLE, Vincent DUBEE 2020-04-03
A trial to evaluate transplantation of ACE2-mesenchymal stem cells in patients diagnosed with COVID-19 pneumonia Coronavirus disease 19 infection, Viral pneumonia ACE2-mesenchymal stem cells alone Celltex Therapeutics Corp China Phase 2 Clinical Status not specified 1 7 2020-04-01
A retrospective study of clinical characteristics and prognosis of novel coronavirus pneumonia (COVID-19) patients with myocardial injury Coronavirus disease 19 infection, Heart injury, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) China-Japan Union Hospital of Jilin University, Tongji Hospital, Huazhong University of Science and Technology Jilin Provincial Science & Technology Department China 2020-03-27 2020-04-27 ChiCTR2000031301 Phase Not Applicable Not yet recruiting 2 1 Month 100 Si Daoyuan 2020-04-01
A trial to evaluate human umbilical cord mesenchymal stem cells for the treatment of COVID-19 patients Coronavirus disease 19 infection allogenic human umbilical cord mesenchymal stem cells alone Female Chinese Academy of Sciences Phase 2 Clinical Status not specified 0 1 2020-03-31
Safety and Efficacy Study of Allogeneic Human Dental Pulp Mesenchymal Stem Cells to Treat Severe novel coronavirus pneumonia (COVID-19) patients Coronavirus disease 19 infection, Viral pneumonia allogeneic human dental pulp mesenchymal stem cells alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Renmin Hospital of Wuhan University China 2020-04-01 2020-07-31 ChiCTR2000031319 Phase 2 Clinical Not yet recruiting 1 4 Months 20 Dr. Chenliang Zhou, Prof Qingsong Ye 2020-04-01
A randomized, open, parallel-controlled clinical trial on the efficacy and safety of Jingyebaidu granules in treating novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Jinyebaidu granule alone, routine treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tongji Hospital, Union Hospital Tongji Medical School Huazhong University Of Science & Technology China 2020-02-12 2020-05-30 ChiCTR2000029755, ChiMCTR2000002999 Phase 4 Clinical Recruiting 1 3 Months 120 Chen Qian, Liu Dong 2020-04-01
Risk factors of death from coronavirus disease 2019 Coronavirus disease 19 infection, SARS coronavirus infection Yokohama City University Japan 2020-03-28 UMIN000039986 Phase Not Applicable Not yet recruiting 1 Nobuyuki Horita 2020-04-01
Study for the Effect of Novel Coronavirus Pneumonia (COVID-19) on the Health of Different People Coronavirus disease 19 infection, Viral pneumonia Healthy volunteers accepted Sichuan University, West China Hospital China 2020-02-10 2022-02-10 ChiCTR2000029754 Phase Not Applicable Recruiting 1 24 Months 1500 Chen Lei, Lai Wanlin 2020-04-01
Effectiveness and safety of hydroxychloroquine sulfate in the preventive treatment of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia hydroxychloroquine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Shanghai Public Health Clinical Center China 2020-03-23 2020-09-30 ChiCTR2000031174 Phase Not Applicable Not yet recruiting 1 6 Months 1000 Lu Shuihua, Xia Lu 2020-04-01
Evaluation of the effectiveness of Ipecac homeopathic remedy in control of Clinical manifestations of COVID-19 Coronavirus disease 19 infection alcohol plus ipecac homeopathic remedy with C30 potency, Hellios homeopathy pharmacy Iran University of Medical Sciences Iran 2020-04-03 IR.IUMS.REC.1399.039, IRCT20140907019073N4 Phase 3 Clinical Recruiting 2 60 Ali Mazaherinezhad, Farbod Rahnama Chitsaz, Proffessor A.Motevalian, Somaye Mahroozade 2020-04-06
Persian Medicine Products in Covid-19 Coronavirus disease 19 infection Iranian medicine alone, herbal therapy alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tabriz University of Medical Sciences Iran 2020-04-03 IR.TBZMED.REC.1398.1318, IRCT20140617018126N2 Phase 3 Clinical Recruiting 1 60 Hojjat Pourfathi Nematabad, Mohammad Samiei 2020-04-06
A medical records based retrospective study for novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Wuhan third Hospital China 2020-03-23 2020-04-30 ChiCTR2000031187 Phase Not Applicable Not yet recruiting 1 1 Month 1292 Pengcheng Luo, Yilin Yin 2020-04-01
Efficacy and optimization of antiviral therapy for novel coronavirus pneumonia (COVID-19) patients Coronavirus disease 19 infection, Viral pneumonia interferon plus lopinavir + ritonavir HIV protease inhibitor Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) 302 Military Hospital of China China 2020-01-10 2020-12-31 ChiCTR2000031196 Phase 2 Clinical Recruiting 1 11 Months 90 Zhe Xu 2020-04-01
Clinical features and prognosis of invasive mechanical ventilation patients with novel coronavirus pneumonia (COVID-19) in Wuhan, China: a single-centered, retrospective, observational study Coronavirus disease 19 infection, Viral pneumonia Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Renmin Hospital of Wuhan University China 2020-03-26 2020-04-06 ChiCTR2000031227 Phase Not Applicable Not yet recruiting 1 40 Qianqian Qiao, Qingta Meng 2020-04-06
Shedding virus and functional prognosis in patients with novel coronavirus pneumonia (COVID-19): a medical records based study Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tongji Hospital, Huazhong University of Science and Technology China 2020-03-25 2020-08-25 ChiCTR2000031244 Phase Not Applicable Not yet recruiting 1 5 Months 200 Shabei Xu, Wei Wang 2020-04-01
Epidemiologic and Clinical Characteristics of novel coronavirus pneumonia (COVID-19) in surgical patients: a medical records based retrospective study Coronavirus disease 19 infection, Viral pneumonia Renmin Hospital of Wuhan University China 2020-01-25 2020-03-12 ChiCTR2000031245 Phase Not Applicable Recruiting 1 1 Month 2000 Jiabao HOU 2020-04-01
A clinical study of ACE-MAB to potentially treat SARS-CoV-2 Coronavirus disease 19 infection, SARS coronavirus infection ACE-MAB (COVID-19), Mabpharm alone Sorrento Therapeutics Inc Mabpharm Ltd Phase Not Applicable Planned 0 2020-04-01
A clinical study to assess efficacy of alpha-1 antitrypsin in the treatment of patients with COVID-19 Coronavirus disease 19 infection alpha-1 antitrypsin alone Grifols SA Phase Not Applicable Planned 0 2020-03-31
A clinical study to assess efficacy of intravenous immunoglobulin in the treatment of patients with COVID-19 Coronavirus disease 19 infection immunoglobulin alone Grifols SA Phase Not Applicable Planned 0 2020-03-31
Epidemiological survey of close contacts of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Chongqing Medical University China 2020-03-01 2021-04-30 ChiCTR2000031246 Phase Not Applicable Not yet recruiting 2 14 Months 68 Kun Chu, Xiaojun Tang 2020-04-06
Study on the mental state of medical staff during the epidemic period of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia West China Hospital China 2020-03-01 2021-03-01 ChiCTR2000031247 Phase Not Applicable Recruiting 1 12 Months 500 Qingqing Xiao, Xiandong Meng 2020-04-01
Outcomes and infectivity of patients with asymptomatic novel coronavirus (COVID-19) infection Coronavirus disease 19 infection, Viral pneumonia Chongqing Medical University China 2020-01-29 2020-06-30 ChiCTR2000031252 Phase Not Applicable No longer recruiting 2 5 Months 60 Qiuling Shi, Yang Pu 2020-04-01
Epidemiological study of novel coronavirus infection (COVID-19) in children at medium/low risk Coronavirus disease 19 infection, SARS coronavirus infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Tongji Hospital, Huazhong University of Science and Technology China 2020-03-16 2020-05-16 ChiCTR2000031293 Phase Not Applicable Recruiting 1 2 Months 240 Xiaoping Luo, Xiuyun Zhou, Yan Hao 2020-04-01
The effect of Trachyspermum copticum syrup on clinical manifestations of patients with COVID-19 Coronavirus disease 19 infection Trachyspermum copticum syrup alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Arak University of Medical Sciences and Health Services Iran 2018-04-09 IR.ARAKMU.REC.1398.342, IRCT20180610040049N3 Phase 3 Clinical No longer recruiting 1 60 Alireza Kamali, Seied Amirhosein Latifi 2020-04-01
A medical records based study for clinical features of novel coronavirus pneumonia (COVID-19) patients and risk factors of death Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The First College Of Clinical Medical Science, China Three Gorges University China 2020-01-14 2020-03-19 ChiCTR2000031296 Phase Not Applicable No longer recruiting 1 2 Months 200 Zhang Rong, Zhou Fating 2020-04-01
Clinical Evaluation of Cordio Application in Adult COVID-19 Virus Positive Patients Coronavirus disease 19 infection, Viral pneumonia Cordio App (Cordio Medical Ltd) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cordio Medical Ltd Israel 2020-04-30 2021-09-30 COV001, NCT04325048 Phase Not Applicable Not yet recruiting 1 17 Months 5000 Miri Yafee, MSc, Zaher Azzam, Prof 2020-04-01
Efficacy and Safety of Emapalumab and Anakinra in Reducing Hyperinflammation and Respiratory Distress in Patients With COVID-19 Infection Coronavirus disease 19 infection, Respiratory distress syndrome anakinra alone, emapalumab alone Interferon gamma ligand inhibitor, Type I IL-1 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Swedish Orphan Biovitrum AB Italy 2020-03-31 2020-09-30 2020-001167-93, NCT04324021, SOBI.IMMUNO-101 Phase 2/Phase 3 Clinical Not yet recruiting 4 6 Months 54 Antonio Pesenti, Prof, Cristina de Min, MD / CMO, Emanuele Nicastri, Dr, Emanuele Nicastri, MD, Franco Franceschini, Prof, Gabriele Missale, Prof, Karin Becker, MSc, Prof 2020-04-01
VIRUS: Viral Infection and Respiratory Illness Universal Study [VIRUS]: COVID19 Registry Coronavirus disease 19 infection, Viral infection Mayo Clinic Foundation US 2020-03-30 2021-04-30 20-002610, NCT04323787, VIRUS Phase Not Applicable Recruiting 0 13 Months 50000 Ayan Sen, MD, Devang Sanghavi, MD, Ognjen Gajic, MD, Rahul Kashya, MBBS, Rahul Kashyap, Vishakha Kumar, MD 2020-04-04
ACT COVID19: Anti-Coronavirus Therapies to Prevent Progression of Coronavirus Disease 2019 (COVID-19) Trial Coronavirus disease 19 infection azithromycin plus chloroquine Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Population Health Research Institute Canada 2020-04-01 2020-12-31 ACT COVID19, NCT04324463, PHRI.ACT.COVID19 Phase 3 Clinical Not yet recruiting 1 9 Months 1500 ACT COVID-19 Study Coordinator, Emilie Belley-Cote, MD PhD, Richard Whitlock, MD PhD 2020-04-01
CYCOV: Cytokine Adsorption in Severe COVID-19 Pneumonia Requiring Extracorporeal Membrane Oxygenation Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia CytoSorb adsorber alone, Extracorporeal Membrane Oxygenation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Klinikum der Albert-Ludwigs Universitaet Freiburg Germany 2020-03-27 2020-11-26 CYCOV, CYCOV, CYCOV_ECMO_2020, NCT04324528 Phase Not Applicable Recruiting 2 8 Months 30 Alexander Supady, Dr., MPH 2020-04-02
CORIMUNO-19: Cohort, Multiple-Randomized, Controlled Trials, Open-label of Immune Modulatory Drugs and Other Treatments in COVID-19 Patients Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia immune modulatory drug therapy alone, sarilumab alone, tocilizumab (intravenous), Roche/Chugai alone IL-6 receptor antagonist, IL-6 receptor modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-03-27 2021-12-31 2020-001246-18, APHP200375, CORIMUNO-19, NCT04324047 Phase Not Applicable Recruiting 4 21 Months 1000 Cécile Kedzia, Matthieu RESCHE-RIGON, MD PhD, Olivier HERMINE, MD-PhD 2020-04-02
CORONADO: 'Coronavirus SARS-CoV2 and Diabetes Outcomes' Coronavirus disease 19 infection, Diabetes mellitus antidiabetic treatment alone, antihypertensive treatment alone CHU De Nantes 2020-03-30 2020-05-08 CORONADO, NCT04324736, RC20_0148 Phase Not Applicable Not yet recruiting 0 1 Month 300 Bertrand Cariou, Pr 2020-04-02
CORIMUNO-SARI: Cohort, Multiple, Randomized, Controlled Trials, Open-label of Immune Modulatory Drugs and Other Treatments in COVID-19 Patients - Sarilumab Trial Coronavirus disease 19 infection, Lung disease, Viral pneumonia sarilumab alone IL-6 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-03-27 2021-12-31 APHP200375-2, CORIMUNO-SARI, NCT04324073 Phase 2/Phase 3 Clinical Recruiting 4 21 Months 240 Matthieu RESCHE-RIGON, MD PhD, Olivier HERMINE, MD-PhD, Xavier Mariette, MD-PHD, matthieu resche-rigon, MD-PhD, olivier HERMINE, MD PHD 2020-04-02
A Study of a Candidate COVID-19 Vaccine Coronavirus disease 19 infection ChAdOx1 nCoV-19 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) University of Oxford UK 2020-03-31 2021-05-31 COV001, NCT04324606 Phase 1/Phase 2 Clinical Recruiting 4 14 Months 510 Andrew Pollard, Prof, Volunteer Recruitment Co-ordinator 2020-04-02
Efficacy and Safety Human Coronavirus Immune Plasma (HCIP) versus Control (SARS-CoV-2 Non-immune Plasma) Among Adults Exposed to COVID-19 Coronavirus disease 19 infection, SARS coronavirus infection anti-SARS-CoV-2 plasma alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sidney Kimmel Comprehensive Cancer Center 2020-04-01 2023-01-31 CSSC-001, IRB00245634, NCT04323800 Phase 2 Clinical Not yet recruiting 0 34 Months 150 Darin Ostrander, PhD, Obi Ezennia, MPH 2020-04-03
PRIORITY: Pregnancy Coronavirus Outcomes Registry Coronavirus disease 19 infection Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of California San Francisco University of California Los Angeles US 2020-03-20 2024-03-31 20-30410, NCT04323839, PRIORITY Phase Not Applicable Recruiting 0 48 Months 1000 Ruth Gebrezghi, Study Coordinator, Vanessa Monzon, Vanessa Vacoby, MD, MAS 2020-04-02
EC-COVID-PCS: Early CPAP in COVID Patients With Respiratory Failure: a Prospective, Cohort Study Coronavirus disease 19 infection, Respiratory failure ACE inhibitor therapy alone, antiviral therapy alone, sartans therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Istituto di Ricerche Farmacologiche Mario Negri Italy 2020-04-06 2020-11-09 EC-COVID-PCS, EC-COVID-PCS-FENICE, NCT04323878 Phase Not Applicable Not yet recruiting 1 7 Months 3000 Elena Garbero, M.Sc, Guido Bertolini, MD 2020-04-01
The investigation on medical adhesive-related skin injury caused by protective dressings of medical staffs during the period of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Nanjing Drum Tower Hospital 2020-01-01 2021-01-01 ChiCTR2000031324 Phase Not Applicable Not yet recruiting 0 12 Months 300 Wei Min 2020-03-31
Convalescent Plasma to Limit Coronavirus Associated Complications Coronavirus disease 19 infection, SARS coronavirus infection c,anti-SARS-CoV-2 onvalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mayo Clinic Foundation US 2020-04-01 2022-12-31 20-002864, NCT04325672 Phase 2a Clinical Not yet recruiting 0 33 Months 20 Michael Joyner, MD, Shelly Roberts, RN 2020-04-02
A prospective, randomized, open-label, controlled clinical study to evaluate the preventive effect of hydroxychloroquine on close contacts after exposure to the Novel Coronavirus Pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia hydroxychloroquine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Renmin Hospital of Wuhan University China 2020-02-20 2021-02-20 ChiCTR2000029803 Phase 0 Clinical Not yet recruiting 1 12 Months 320 Shoumeng Han, Zhan Zhang 2020-04-01
Prevalence and Incidence of COVID-19 Infection in Patients With Chronic Plaque Psoriasis on Immunosuppressant Therapy Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Universita di Verona Azienda Ospedaliera Universitaria Integrata Di Verona Italy 2020-04-01 2020-12-31 GISONDI 4, NCT04324866 Phase Not Applicable Not yet recruiting 1 9 Months 300 Paolo Gisondi 2020-03-31
A clinical study to assess anti-SARS-CoV-2 hyperimmune globulin therapy as a therapy for the treatment of patients with COVID-19 disease Coronavirus disease 19 infection hyperimmune globulin alone Grifols SA Biomedical Advanced Research and Development Authority (BARDA), Food and Drug Administration Phase Not Applicable Planned 0 2020-03-31
Comparison of vitamin D3 and N-acetylcysteine prescription in COVID-19 patients and their effect on recovery process Coronavirus disease 19 infection N acetylcysteine alone, Vitamin D3 alone, standard treatment alone, N acetylcysteine plus Vitamin D3 Abadan School of Medical Sciences Iran 2020-03-29 IR.ABADANUMS.REC.1398.118, IRCT20200324046850N1 Phase 3 Clinical Recruiting 1 100 Sara Mobarak 2020-03-31
Efficacy of the myrtle syrup in the treatment of novel corona Coronavirus disease 19 infection, Viral pneumonia myrtle (Myrtus Communis) syrup alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Kerman University of Medical Sciences Iran 2020-04-02 IR.KMU.REC.1399.015, IRCT20180923041093N3 Phase 3 Clinical Recruiting 1 100 Abbas Pardakhti, Maryam Azimi 2020-04-03
Shen-Fu injection in the treatment of severe novel coronavirus pneumonia (COVID-19): a multicenter, randomized, open-label, controlled trial Coronavirus disease 19 infection, Viral pneumonia Shen-Fu injection alone, conventional treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Peking University Third Hospital China 2020-02-01 2020-12-31 ChiCTR2000030043 Phase 4 Clinical Not yet recruiting 14 11 Months 300 Ma Penglin, Wang Zongyu 2020-03-31
A Medical Records Based Retrospective Study for Clinical Characteristics of severe Novel Coronavirus Pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Xiangya Hospital Of Central South University China 2020-03-24 2020-05-31 ChiCTR2000031199 Phase Not Applicable Recruiting 1 2 Months 150 Fan Rong, Wang Yang 2020-03-31
Study for the effect of Moxibustion Guidance and Intervention based on internet for the discharged patients with novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia moxibustion treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) People’s Hospital of Zhengzhou China 2020-03-01 2022-02-28 ChiCTR2000031203, ChiMCTR2000003156 Phase 0 Clinical Recruiting 1 24 Months 28 Fu Liran 2020-04-01
Cancelled by the investigator A clinical study for 'Huo-Shen' particles in the treatment of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Huo-Shen particles alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shenzhen national medicine inheritance medical research institute co. LTD China 2020-03-24 ChiCTR2000030118, ChiMCTR2000003048 Phase 0 Clinical Terminated 1 120 Yuan Yongming, Zhang Jingsha 2020-03-31
Cancelled by the investigator Humanistic Care in Patients With Novel Coronavirus Pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia psychological and physical rehabilitation based humanistic care alone, routine regimen alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The Second Hospital of Xi'An Jiaotong University China 2020-02-24 ChiCTR2000030136 Phase 0 Clinical Terminated 1 130 Gong Shouping, Ma Xiaorong 2020-03-31
Efficacy of the barley-based remedy in the treatment of novel corona Coronavirus disease 19 infection, Viral pneumonia barley-based medication alone, drug pack therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Kerman University of Medical Sciences Iran 2020-04-02 IR.KMU.REC.1399.014, IRCT20180923041093N4 Phase Not Applicable Recruiting 1 100 Abbas Pardakhti, Maryam Azimi 2020-04-03
Cancelled by the investigator Humanistic Care in Healthcare Workers in Novel Coronavirus Pneumonia (COVID-19) Coronavirus disease 19 infection, Depression, Post traumatic stress disorder, Viral pneumonia humanistic care alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) The Second Hospital of Xi'An Jiaotong University China 2020-02-24 ChiCTR2000030137 Phase 0 Clinical Terminated 1 130 Gong Shouping, Ma Xiaorong 2020-03-30
Quality of life among Chinese residents during and after novel coronavirus pneumonia (COVID-19) outbreak: an online survey Coronavirus disease 19 infection, Viral pneumonia health advice based on online survey alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry The Jockey Club School of Public Health and Primary Care China 2020-02-20 2022-05-19 ChiCTR2000030223 Phase Not Applicable Recruiting 1 27 Months 5000 Daisy Dexing Zhang 2020-03-30
Efficacy evaluation of an herbal compound 'Fluherb' on clinical symptoms and paraclinical parameters in highly suspected COVID-19 patients: a controlled, randomized clinical trial Coronavirus disease 19 infection Fluherb supplement alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Mashhad University of Medical Sciences Iran 2020-03-28 IR.MUMS.REC.1398.315, IRCT20200323046841N1 Phase 2/Phase 3 Clinical Recruiting 1 30 Dr. Mohsen Tafaghodi, Mahdi Yousefi 2020-03-30
Clinical study for the effects of ACEIs/ARBs on the infection of novel coronavirus pneumonia (CoVID-19) Coronavirus disease 19 infection, Viral pneumonia angiotensin II receptor blockers (ARBs) alone, angiotensin-converting enzyme inhibitors (ACEIs) alone The First Affiliated Hospital of Wenzhou Medical University China 2020-03-02 ChiCTR2000030453 Phase Not Applicable Not yet recruiting 1 100 Yanling Shi 2020-03-30
JYCO: A multicenter, single-blind, randomized, controlled clinical trial for chloroquine phosphate in the treatment of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia chloroquine phosphate alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Beijing Institute of Pharmacology and Toxicology, Beijing YouAn Hospital China 2020-01-30 ChiCTR2000031204, JYCO, JYCO Phase 2 Clinical Recruiting 3 300 Jin Ronghua, Zhong Wu 2020-03-30
Clinical study on the correlation between novel coronavirus pneumonia (COVID-19) clinical rehabilitation assessment and prognosis Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The First Rehabilitation Hospital of Shanghai, Wuhan third Hospital China 2020-03-31 2022-03-31 ChiCTR2000031214 Phase 0 Clinical Not yet recruiting 1 24 Months 60 GAO Tian-lin, ZHOU Zhe 2020-03-31
Clinical Application of ECMO in the Treatment of Patients with Very Serious Respiratory Failure due to novel Coronavirus Pneumonia (COVID-19) Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia extracorporeal membrane oxygenation (ECMO) alone Capital Medical University, Wuhan Jinyintan Hospital Ministry of Science and Technology of the People´s Republic of China China 2020-02-01 2021-01-31 ChiCTR2000029804 Phase Not Applicable Recruiting 3 12 Months 100 Liu Ying, Wu Wenjuan 2020-04-02
The effect of stem cell transplantation in the treatment of COVID-19 Coronavirus disease 19 infection, Viral pneumonia cord-derived mesenchymal stem cells (SinaCell) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) MOM research and innovation center Iran 2020-03-24 IR.IUMS.REC.1398.1400, IRCT20140528017891N8 Phase 3 Clinical Recruiting 1 10 Amirhossein Asgary, Elham Jamshidi, Nader Tavakoli, Omid Moradimoghadam 2020-04-02
DEXA-COVID19: Efficacy of Dexamethasone Treatment for Patients With ARDS Caused by COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome dexamethasone (Indukern) alone, standard intensive care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dr. Negrin University Hospital Centro De Investigación Biomédica En Red De Enfermedades Hepáticas Y Digestivas (Ciberehd), Li Ka Shing Knowledge Institute Spain 2020-04-01 2020-10-30 2020-001278-31, DEXA-COVID19, NCT04325061 Phase 4 Clinical Not yet recruiting 15 6 Months 200 Alberto Martínez-Ruiz, MD, PhD, Alfonso Ambrós, MD, PhD, Arthur Slutsky, MD, Carlos Ferrando, MD, PhD, Carmen Martín, MD, César Pérez-Calvo, MD, Domingo Martínez, MD, Emilio Maseda, MD, PhD, Fernando Ramasco, MD, PhD, Fernando Suarez-Sipmann, MD, PhD, Gerardo Aguilar, MD, PhD, Gonzalo Tamayo, MD, PhD, Iñaki Bilbao-Villasante, Jesús Villar, MD, José A Carbonell, MD, José Ferreres, MD, PhD, José I Gómez-Herreras, MD, PhD, José M Añón, MD, PhD, Juan A Soler, MD, PhD, Lorena Fernández, MD, PhD, Marina Varela, MD, PhD, Pablo Serna-Grande, MD, Pilar Diaz-Parada, MD, Rafael del Campo, MD, Tomás Muñoz, MD, PhD, Álvaro Castellanos, MD, PhD, Ánxela Vidal, MD 2020-04-02
Comparison of the Effect of Sofosbuvir + Daclatasvir (Sovodac) and Ribavirin in Covid-19 Coronavirus disease 19 infection daclatasvir+ sofosbuvir alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Abadan School of Medical Sciences Iran 2020-03-18 IR.ABADANUMS.REC.1398.113, IRCT20200324046850N2 Phase 2 Clinical Recruiting 1 60 Sara Mobarak, Sara Mobark 2020-03-31
ENACOVID: Efficacy of Addition of Naproxen in the Treatment of Critically Ill Patients Hospitalized for COVID-19 Infection Coronavirus disease 19 infection, Viral pneumonia Standard of care alone, naproxen alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-03-27 2021-06-27 APHP200387, ENACOVID, NCT04325633 Phase 3 Clinical Not yet recruiting 1 15 Months 584 Anny SLAMA SCHWOK, MD, Frédéric ADNET, MD, PhD 2020-03-31
CAPACITY-COVID: Cardiac Complications in Patients With SARS Coronavirus 2 Registry Cardiovascular disease, Coronavirus disease 19 infection, SARS coronavirus infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitair Medisch Centrum Utrecht Netherlands 2020-03-23 2021-06-23 20-161/C, CAPACITY-COVID, NCT04325412 Phase Not Applicable Recruiting 1 15 Months 1000 Folkert W. Asselbergs, MD, PhD, Marijke Linschoten, MD, Prof. Dr. F.W. Asselbergs 2020-04-02
Recommendations of Integrated Traditional Chinese and Western Medicine for Novel Coronavirus Pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Western medicine therapy alone, traditional Chinese medicine therpy alone The Affiliated Hospital of Chengdu University of Traditional Chinese Medicine Science & Technology Department of Sichuan Province China 2020-02-03 2020-05-01 ChiCTR2000029549, ChiMCTR2000002983 Phase Not Applicable Recruiting 1 2 Months 400 Tang Shiyun, Xie Chunguang 2020-04-01
A phase I clinical study of STI-6991 (I-Cell) for the potential im prevention of coronavirus COVID-19 caused by SARS-CoV-2 (2019-nCoV) Coronavirus disease 19 infection, SARS coronavirus infection STI-6991 alone Sorrento Therapeutics Inc US 2020-06-30 Phase 1 Clinical Planned 0 2020-04-02
A clinical study to assess Ampligen for the potential treatment of subjects with COVID-19 Coronavirus disease 19 infection rintatolimod alone 2,5-Oligoadenylate synthetase stimulator, Interferon type I receptor agonist, Ribonuclease stimulator, TLR-3 agonist AIM ImmunoTech Inc National Institute of Infectious Diseases Japan Japan Phase Not Applicable Not yet recruiting 2 Dr. Hideki Hasegawa, Dr. Takeshi Ichinohe 2020-04-01
Chinese medicine prevention and treatment program for novel coronavirus pneumonia (COVID-19): a perspective, sing-arm trial Coronavirus disease 19 infection, Viral pneumonia traditional Chinese medicine therapy alone, western medicine therapy alone Zhejiang Chinese Medical University China 2020-02-06 2020-04-30 ChiCTR2000029578 Phase 0 Clinical Recruiting 1 2 Months 1000 Chengping Wen, Zhijun Xie 2020-04-01
DAS-181 for Severe COVID-19: Compassionate Use Coronavirus disease 19 infection, SARS coronavirus infection DAS-181 alone Exo-alpha sialidase modulator, Muscarinic receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Renmin Hospital of Wuhan University Ansun BioPharma Inc China 2020-03-06 2020-04-30 DAS181-SARS-COV-2, NCT04324489 Phase 2 Clinical Recruiting 1 1 Month 4 Ke Hu, MD, Zuojiong Gong, MD, Zuojiong Guong, MD 2020-04-03
Clinical characteristics and death risk factors in severe novel coronavirus pneumonia (COVID-19) patients: a single-center respective analysis based on medical records Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tongji Medical College China 2020-04-01 2020-04-10 ChiCTR2000031327 Phase Not Applicable Not yet recruiting 1 120 Hong Qiu, Hui Peng 2020-04-01
A Retrospective Study for Preventive Medication in Tongji Hospital During the Epidemic of Novel Coronavirus Pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Jinyebaidu granule alone, angiotensin II receptor blockers therapy alone, other prophylactic drugs therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tongji Hospital, Huazhong University of Science and Technology China 2020-02-12 2020-05-30 ChiCTR2000029728 Phase Not Applicable Not yet recruiting 1 3 Months 500 Chen Qian, Liu Dong 2020-04-01
The protective effect of sleep psychology and music therapy of novel coronavirus pneumonia (COVID-19) mild and moderate type patients Coronavirus disease 19 infection, Viral pneumonia basic therapy alone, sleep-aid music therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) First Teaching Hospital of Tianjin University of Traditional Chinese Medicine China 2020-03-13 2020-04-30 2020003, ChiCTR2000031328 Phase Not Applicable Recruiting 1 1 Month 60 Yuan-hao Wu 2020-04-01
NIKE-C19: Prognostic Factors Keeping Track for Covid19 Pneumonia Cardiovascular disease, Chronic obstructive pulmonary disease, Coronavirus disease 19 infection, Hypertension, Non-insulin dependent diabetes, Obesity, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Catholic University of the Sacred Heart Italy 2020-03-31 2020-06-15 20202503, NCT04324684, NIKE-C19 Phase Not Applicable Recruiting 2 2 Months 198 Anna Caprodossi, Geltrude Mingrone, Geltrude Mingrone, MD PhD, Gian Ludovico Rapaccini, MD, Giovanni Addolorato, MD, Massimo Montalto, MD, Maurizio Pompili, MD 2020-04-03
A pilot study to diagnose COVID-19 in subject obtained oropharyngeal and salivary samples through FDA approved gold standard of COVID-19 testing Coronavirus disease 19 infection FDA approved gold standard of COVID-19 testing alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) ZoomCare Company PeaceHealth System Services US Phase Not Applicable Recruiting 0 2020-04-02
Epidemiological investigation and clinical characteristics analysis of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia The First People's Hospital of Huaihua Hunan Provincial Natural Science Foundation China 2020-01-31 2020-08-07 ChiCTR2000029734 Phase Not Applicable Recruiting 1 6 Months 40 Chengfeng Qiu 2020-03-31
The effect of Gymnastic Qigong Yangfeifang on functional recovery and quality of life in patients with mild novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Qigong Yangfeifang alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Shanghai Public Health Clinical Center, Shanghai University of Traditional Chinese Medicine, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Shanghai University of Traditional Chinese Medicine China 2020-02-18 2022-02-19 ChiCTR2000029976, ChiMCTR2000003032 Phase 0 Clinical Recruiting 1 24 Months 80 Shan Chunlei, Xu Shutian 2020-03-31
Influence of novel coronavirus pneumonia (COVID-19) on disease activity, medical and mental condition of patients with rheumatic diseases Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Guangdong Provincial People's Hospital China 2020-03-11 2023-12-31 ChiCTR2000031329 Phase Not Applicable Recruiting 1 45 Months 120 Tianwang Li 2020-03-31
Expanded Access Treatment Protocol: Remdesivir (RDV; GS-5734) for the Treatment of SARS-CoV2 (CoV) Infection Coronavirus disease 19 infection remdesivir alone RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gilead Sciences Inc US GS-US-540-5821, NCT04323761 Phase Not Applicable Recruiting 0 Gilead Clinical Study Information Center, Gilead Study Director 2020-04-03
A medical records based study for risk assessment and treatment timing of invasive fungal infection in novel coronavirus pneumonia (COVID-19) critical patients Candida infection, Coronavirus disease 19 infection, Viral pneumonia antifungal therapy alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tongji Hospital, Huazhong University of Science and Technology China 2020-04-01 2020-08-31 ChiCTR2000030717 Phase Not Applicable Not yet recruiting 3 5 Months 260 Minghao Fang, Xiaojing Zou 2020-04-01
A Phase I/II Study of Universal Off-the-shelf NKG2D-ACE2 CAR-NK Cells for Therapy of COVID-19 Coronavirus disease 19 infection, Viral pneumonia ACE2 CAR-NK cells alone, IL-15 NK cells alone, NK cells alone, NKG2D CAR-NK cells alone, NKG2D-ACE2 CAR-NK cells alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chongqing Infectious Disease Medical Center Chongqing Sidemu Biotechnology Co. Ltd China 2020-03-21 2020-09-30 CHONGQINGPUBLICHMC, NCT04324996 Phase 1/Phase 2 Clinical Recruiting 1 6 Months 90 Jimin Gao, PhD, Min Liu, A.B 2020-03-31
AI based prognostic evaluation of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia prognostic evaluation alone Huazhong University of Science and Technology China 2020-04-01 2021-03-31 ChiCTR2000031336 Phase Not Applicable Not yet recruiting 1 12 Months 1000 Fan Yang, Wenliang Fan 2020-04-06
Retrospective and Prospective Study for Nosocomial infection in Stomatology Department under the Background of novel coronavirus pneumonia (COVID-19) epidemic period Coronavirus disease 19 infection, Viral pneumonia Male Tongji Hospital, Huazhong University of Science and Technology China 2020-03-14 2020-04-30 ChiCTR2000030895 Phase 1 Clinical Not yet recruiting 1 1 Month 1000 Jingyu Hu, Jingzhi Ma 2020-04-01
A clinical trial of Standard Q COVID-19 IgM/IgG Rapid Antibody Test for the qualitative presumptive detection of specific IgM and IgG antibodies associated with the 2019 novel coronavirus (SARS-CoV-2) Coronavirus disease 19 infection, SARS coronavirus infection Standard Q COVID-19 IgM/IgG Rapid Antibody Test alone Henry Schein Inc Phase Not Applicable Status not specified 0 2020-03-30
Combined diagnostic value of novel coronavirus (2019-CoV) infection detected by NLR and CRP Coronavirus disease 19 infection, Viral pneumonia blood routine test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kongjiang hospital China 2020-01-21 2020-06-30 ChiCTR2000030942 Phase Not Applicable No longer recruiting 1 5 Months 191 MINGLI LIU 2020-04-02
Cancelled by investigator A cox regression analysis of prognosis of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Cox regression analysis alone Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Wuhan Asia General Hospital China 2020-02-01 2020-02-18 ChiCTR2000029820 Phase Not Applicable Suspended 1 410 Huang Keqiang 2020-03-31
Analysis of clinical characteristics of severe novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Peking Union Medical College Hospital, Wuhan Jinyintan Hospital Ministry of Science and Technology of the People´s Republic of China China 2020-01-01 2021-01-31 ChiCTR2000029805 Phase Not Applicable Recruiting 1 13 Months 100 Liu Ying, Wu Wenjuan 2020-03-31
Clinical observation and research of severe acute respiratory syndrome coronavirus 2(COVID-19) infection in perinatal newborns Coronavirus disease 19 infection, SARS coronavirus infection Newborn Infants (up to 5 months), Infants (6-23 months) West China Second University Hospital China 2020-01-25 2021-01-01 ChiCTR2000029959 Phase Not Applicable Recruiting 2 11 Months 30 Jun Tang 2020-03-31
Clinical efficacy of TCM syndrome differentiation in the treatment of severe/critical type of novel coronavirus pneumonia (COVID-19): a prospective, observational, one-arm clinical study Coronavirus disease 19 infection, Viral pneumonia standard treatment alone, traditional chinese medicine alone Chengdu University of Traditional Chinese Medicine State Administration of Traditional Chinese Medicine People's Republic of China China 2020-03-01 2020-12-31 ChiCTR2000030962, ChiMCTR2000003153 Phase Not Applicable Not yet recruiting 2 10 Months 60 Peiyang Gao, Shikun Deng 2020-04-02
A Medical Based Retrospective Study for Clinical Characteristics, Treatments and Prognosis of Patients with Novel Coronavirus Pneumonia (COVID-19) in WuHan Coronavirus disease 19 infection, Viral pneumonia Shanghai Changzheng Hospital, Wuhan Hankou Hospital China 2020-03-01 2020-12-31 ChiCTR2000030961 Phase Not Applicable Recruiting 2 10 Months 2000 Miao Yushan, Tang Hao 2020-03-31
Myocardial injury and arrythmias in the novel coronavirus pneumonia (COVID-19) patients Coronavirus disease 19 infection, Heart arrhythmia, Heart injury, Pneumonia Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fifth Affiliated Hospital, Sun Yat-Sen University China 2020-01-18 2020-04-01 ChiCTR2000030952 Phase Not Applicable Recruiting 1 2 Months 93 Chen Jian 2020-03-31
TOCIVID: Anti-IL6 Treatment of Serious COVID-19 Disease With Threatening Respiratory Failure Coronavirus disease 19 infection, Viral pneumonia Standard medical care alone, sarilumab alone, tocilizumab (intravenous), Roche/Chugai alone, tocilizumab (subcutaneous), Roche/Chugai alone IL-6 receptor antagonist, IL-6 receptor modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Frederiksberg University Hospital Denmark 2020-04-04 2021-06-01 APPI2-CV-2020-01, NCT04322773, TOCIVID Phase 2 Clinical Not yet recruiting 1 13 Months 200 Lars Erik Kristensen, PhD, Line Rustad 2020-04-04
An observational study for cardiac and pulmonary ultrasound and evaluation of treatment of severe patients with novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia ultrasound alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Wuhan Union Hospital, China, Xiangya Hospital Of Central South University China 2020-03-20 2020-05-31 ChiCTR2000030919 Phase Not Applicable Not yet recruiting 1 2 Months 80 Zhang Lina, Zhao Chunguang 2020-03-30
Evaluation of the effect of taking tricholoma matsutake, cannabis sativa capsule and dendrobium candidum to nutrition intervention of patients with novel coronavirus pneumonia (COVID-19) during convalescence Coronavirus disease 19 infection, Viral pneumonia dendrobium candidum alone, tricholoma matsutake alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The 2nd People's Hospital of Ningbo China 2020-02-01 2021-05-01 2020YJY0201, ChiCTR2000030920 Phase Not Applicable Recruiting 1 15 Months 100 Ting Cai 2020-03-30
Prospective, open-label, controlled, multicenter, cohort study of long-acting interferon plus ribavirin in patients with novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia long-acting interferon alpha-2a plus ribavirin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) First People's Hospital of Foshan China 2020-02-26 2020-08-26 ChiCTR2000030922 Phase 2 Clinical Recruiting 4 6 Months 30 Bin Zhang/Yinong Ye, Haiming Yan 2020-04-02
The treatment and diagnosis plan of integrated traditional Chinese and Western medicine for novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia TCM formula 1 alone, TCM formula 2 alone, TCM formula 3 alone, TCM formula 4 alone, TCM formula 5 alone, TCM formula 6 alone, Western medicine alone The Affiliated Hospital of Shaanxi University of Chinese Medicine Shaanxi Provincial Science and Technology Department China 2020-01-15 2020-04-16 ChiCTR2000030923, ChiMCTR2000003148 Phase 0 Clinical Recruiting 1 3 Months 400 Lei Genping 2020-03-30
Hydroxychloroquine for the Treatment of Patients With Mild to Moderate COVID-19 to Prevent Progression to Severe Infection or Death Coronavirus disease 19 infection hydroxychloroquine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rambam Health Care Campus Rabin Medical Center Israel 2020-03-31 2020-12-31 0154-20-RMB, NCT04323631 Phase 0 Clinical Not yet recruiting 1 9 Months 1116 Paul 2020-03-30
CoV-CONTACT-SERO: Factors Associated With a Positive SARS-CoV-2 Serology in Contact Subjects at High/Moderate Risk of Coronavirus SARS-CoV-2 Infection Coronavirus disease 19 infection SARS-CoV-2 serology alone, Whole exome sequencing alone INSERM France 2020-03-09 2020-05-01 2020-A00609-30, C20-16, CoV-CONTACT-SERO, NCT04322279 Phase Not Applicable Recruiting 1 1 Month 300 Bruno Lina, MD, Xavier Duval, MD 2020-03-30
LUSCOVID19: Simple, Safe, Same: Lung Ultrasound for COVID-19 Coronavirus disease 19 infection Catholic University of the Sacred Heart Fondazione IRCCS Policlinico San Matteo, L'Azienda USL Nord Ovest, Lodi Hospital, Universita Degli Studi di Pavia, University of Trento Italy 2020-04-01 2021-01-15 0013226/20, LUSCOVID19, NCT04322487 Phase Not Applicable Not yet recruiting 8 9 Months 100 Andrea Smargiassi, MD, PhD, Gino Soldati, MD, Libertario Demi, PhD, Riccardo Inchingolo, MD, PhD 2020-03-30
Developing and evaluating of artificial intelligence triage system for suspected novel coronavirus pneumonia (COVID-19): a retrospective study Coronavirus disease 19 infection, Viral pneumonia artificial intelligence triage system alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Infervision, Tianyou hospital, Tongji Medical College, Xianning Central Hospital China 2020-03-20 2020-06-30 ChiCTR2000030951 Phase Not Applicable Not yet recruiting 3 3 Months Shabei Xu, Wei Wang 2020-03-30
CovidSurg: Outcomes of Surgery in COVID-19 Infection: International, Cohort Study Coronavirus disease 19 infection elective surgery alone The University of Birmingham 2020-03-31 2020-09-30 CS-20200324, CovidSurg, NCT04323644 Phase Not Applicable Not yet recruiting 0 6 Months 1000 Aneel Bhangu, Dmitri Nepogodiev 2020-03-30
Study for novel coronavirus pneumonia (COVID-19) patients etiology and immune response and guidance for vaccine design Coronavirus disease 19 infection, Viral pneumonia West China Hospital China 2020-02-09 2022-02-10 ChiCTR2000030950 Phase 0 Clinical Recruiting 1 24 Months Liujie, Yangqi 2020-03-30
Traditional Chinese Medicine for Severe COVID-19 Coronavirus disease 19 infection Traditional Chinese medicine alone, conventional treatment alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Xiyuan Hospital China Academy Of Chinese Medical Sciences China 2020-03-31 2020-04-30 2020XLA015-1, NCT04323332 Phase 3 Clinical Not yet recruiting 1 1 Month 50 Hao Li, Prof., Hao Li, Professor, Li Hao, professor 2020-03-30
Escin in Patients With Covid-19 Infection (add-on-COV2) Coronavirus disease 19 infection, Viral pneumonia conventional antiviral drug therapy alone, escin alone, sodium escinate alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Universita' Degli Studi "Magna Graecia" Di Catanzaro Azienda Ospedaliera Pugliese Ciaccio, Azienda Ospedaliera Universitaria Mater Domini di Catanzaro Italy 2020-03-23 2020-08-30 COVID-19 ADD-ON THERAPY, NCT04322344 Phase 2/Phase 3 Clinical Recruiting 1 5 Months 120 LUCA GALLELLI, Luca Gallelli 2020-03-30
Effect of auricular point pressing on insomnia of novel coronavirus pneumonia (COVID-19) patients: a randomized controlled trial Coronavirus disease 19 infection, Viral pneumonia auricular point pressing alone, normal treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Xiyuan Hospital China Academy Of Chinese Medical Sciences China ChiCTR2000030996, ChiMCTR2000003137 Phase 0 Clinical Recruiting 1 60 Jing Li 2020-03-31
Efficacy and Safety of Pirfenidone in the Treatment of Severe Post-Novel Coronavirus Pneumonia (COVID-19) Fibrosis: a prospective exploratory experimental medical study Coronavirus disease 19 infection, Fibrosis, Viral pneumonia pirfenidone alone, routine-life support symptomatic treatment alone PDGF receptor antagonist, TGF beta receptor antagonist, p38 MAP kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The First Affiliated Hospital of Guangzhou Medical College Beijing Pharmaceutical Group Companies China 2020-03-06 2020-12-30 ChiCTR2000030892 Phase 0 Clinical Recruiting 1 9 Months 40 Qun Luo 2020-03-31
Study for effects of crisis intervention based on positive psychology for medical staffs working in the novel coronavirus pneumonia (COVID-19) field Coronavirus disease 19 infection, Viral pneumonia Positive Psychological Guidance Group Counseling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) People’s Hospital of Zhengzhou China ChiCTR2000030893 Phase Not Applicable Not yet recruiting 1 50 Wang He 2020-03-31
The Use of Angiotensin Converting Enzyme Inhibitors and Incident Respiratory Infections, Are They Harmful or Protective? Coronavirus disease 19 infection, Influenza virus infection, Respiratory tract infection ACE inhibitor therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University College London 1998-01-01 2020-03-31 ISAC17_205R, NCT04322786 Phase Not Applicable No longer recruiting 0 267 Months 1302508 2020-03-30
COLCORONA: Colchicine Coronavirus SARS-CoV2 Trial (COVID-19) Coronavirus disease 19 infection, Lung disease colchicine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Montreal Health Innovations Coordinating Center, Montreal Heart Institute CGI Inc, DACIMA Software, Pharmascience Inc, Quebec government Canada 2020-03-23 2020-09-30 COLCORONA, MHIPS-2020-001, NCT04322682 Phase 3 Clinical Recruiting 1 6 Months 6000 Chantal Lacoste, Jean-Claude Tardif, M.D, Jean-Claude Tardif, MD, Montreal Heart Institute, Zohar Bassevitch, B.SC. 2020-04-01
A study of peripheral blood T lymphocyte subsets in patients with novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) People’s Hospital of Zhengzhou China 2020-03-31 2021-03-31 ChiCTR2000031115 Phase 0 Clinical Recruiting 1 12 Months 30 Jiao Xianfa, Wang Hongyu 2020-03-30
A medical records based study for the value of upper respiratory tract virus detection in the assessment of rehabilitation of novel coronavirus pneumonia (COVID-19) patient Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Renmin Hospital of Wuhan University China 2020-03-12 2020-06-12 ChiCTR2000030993 Phase Not Applicable Not yet recruiting 1 3 Months 300 Binru Wang 2020-03-30
Study for metagenomics of patients with novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fifth Affiliated Hospital, Sun Yat-Sen University China 2020-02-05 2020-12-01 ChiCTR2000031104 Phase Not Applicable Recruiting 1 9 Months 200 Pengfei Pang 2020-04-06
A clinical trial of Vesper, a unique ventilator expansion device, for potential treatment of COVID-19 Coronavirus disease 19 infection Vesper alone Prisma Health-Upstate Phase Not Applicable Status not specified 0 2020-03-27
Analysis for the mental health status of residents in Jingzhou during the outbreak of the novel coronavirus pneumonia (COVID-19) and corresponding influencing factors Coronavirus disease 19 infection, Viral pneumonia Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Jingzhou Mental Hospital China 2020-02-10 2020-04-30 ChiCTR2000030902 Phase Not Applicable Recruiting 1 2 Months 1000 Deng Xiaopeng, Zhang Xinfeng 2020-03-30
Clinical Application and Theoretical Discussion of Fu-Zheng Qing-Fei Thought in Treating Non-Critical Novel Coronavirus Pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Western medicine treatment alone, traditional Chinese medicine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Zhengzhou University China 2020-02-06 2021-03-30 ChiCTR2000030896, ChiMCTR2000003125 Phase 0 Clinical Recruiting 1 13 Months 24 Wang Dazhong, Yu Zhongling 2020-03-30
Retrospective analysis of epidemiology and transmission dynamics of patients confirmed with Coronavirus Disease (COVID-19) in Hong Kong Coronavirus disease 19 infection, Viral pneumonia Chinese University of Hong Kong China 2020-03-09 2020-03-14 ChiCTR2000030901 Phase Not Applicable No longer recruiting 1 100 Peter Choi Ching Lam, Prof. Christopher CK Lai 2020-03-30
Evaluation on the effect of Chushifangyi prescription in preventing novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Chushifangyi alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Affiliated Hospital of Changchun University of Traditional Chinese Medicine China 2020-01-24 2020-12-31 ChiCTR2000030898, ChiMCTR2000003124 Phase Not Applicable Recruiting 2 11 Months 1000 Tian Lin, Wang Tan 2020-03-30
A phase II clinical study of bucillamine for the treatment of subjects with coronavirus disease (COVID-19) Coronavirus disease 19 infection repurposed formulation of bucillamine (gout/cystinuria/Wilson disease), Revive Therapeutics alone Xanthine oxidase inhibitor Pharm-Olam International, Revive Therapeutics Ltd US Phase 2 Clinical Planned 0 2020-04-02
A medical records based study for the diagnosis and prognosis prediction AI model of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Shanghai Changzheng Hospital, Wuhan Hankou Hospital China 2020-02-01 2023-02-28 ChiCTR2000030992 Phase Not Applicable Recruiting 1 37 Months 1000 Fan Li, Tang Hao 2020-03-30
A clinical trial to evaluate Xifaxan (rifaximin) in combination with established therapies, supportive care and other investigative therapies for the treatment of the symptoms of gastrointestinal distress and pulmonary compromise associated with COVID-19 infection Coronavirus disease 19 infection, Gastrointestinal disease, Lung disease other therapies alone, rifaximin alone, supportive care treatment alone RNA polymerase inhibitor Salix Pharmaceuticals Inc US Phase Not Applicable Planned 0 2020-03-30
A Medical Records Based Study for SARS-COV-2 RNA Level in Blood and Excrement of Novel Coronavirus Pneumonia (COVID-19) Convalescent Patients Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The 2nd People's Hospital of Ningbo China 2020-03-19 2020-09-19 ChiCTR2000031014 Phase Not Applicable Not yet recruiting 1 6 Months 100 Rengbin Ji 2020-04-02
Favipiravir Combined With Tocilizumab in the Treatment of novel coronavirus pneumonia (COVID-19) - A Multicenter, Randomized, Controlled Trial Coronavirus disease 19 infection, Viral pneumonia favipiravir plus tocilizumab RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Peking University First Hospital China 2020-03-01 2020-05-01 ChiCTR2000030894 Phase 4 Clinical Recruiting 10 2 Months 150 Guiqiang Wang, Hong Zhao 2020-03-30
B-DT-COV2: Biomarkers for Identification of SARS-COV-2 Infection Coronavirus disease 19 infection, SARS coronavirus infection Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Universita' Degli Studi "Magna Graecia" Di Catanzaro Azienda Ospedaliera Pugliese Ciaccio, Azienda Ospedaliera Universitaria Mater Domini di Catanzaro Italy 2020-03-24 2020-08-30 B-DT-COV2, COVID-19 BIOMARKERS, NCT04322513 Phase Not Applicable Recruiting 1 5 Months 110 LUCA GALLELLI, Luca Gallelli, 2020-04-01
EELV and TPP in Covid-19: Prospective, observational study to evaluate transpulmonary pressure, end expiratory lung volume and intraabdominal pressure in mechanical ventilated patients with Covid-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) KKH BergstrasseAbteilung Anästhesie/Intensivmedizin Germany 2020-03-26 DRKS00021186, EELV and TPP in Covid-19, S-579/2016 Phase Not Applicable Recruiting 1 45 Armin Kalenka 2020-03-30
Internet based solution focused brief therapy treating adolescent anxiety under the novel coronavirus pneumonia (COVID-19) outbreak: a randomized controlled trial Coronavirus disease 19 infection, Viral pneumonia internet based solution focused brief therapy alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Beijing Normal University China 2020-04-03 2020-08-08 ChiCTR2000030989 Phase Not Applicable Not yet recruiting 1 4 Months 76 Shitao Chen 2020-03-30
Treatment of Moderate to Severe Coronavirus Disease (COVID-19) in Hospitalized Patients Coronavirus disease 19 infection, SARS coronavirus infection baricitinib alone, hydroxychloroquine sulfate alone, lopinavir + ritonavir alone, sarilumab alone HIV protease inhibitor, IL-6 receptor antagonist, Jak1 tyrosine kinase inhibitor, Jak2 tyrosine kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Nova Scotia Health Authority Dalhousie University Canada 2020-03-31 2021-07-31 NCT04321993, SAIL-004 Phase 2 Clinical Not yet recruiting 1 16 Months 1000 Barbara Goodall, Lisa Barrett 2020-03-30
Perioperative immune prediction and intervention of tumor patients undergoing surgery during the novel coronavirus pneumonia (COVID-19) outbreak period Coronavirus disease 19 infection, Viral pneumonia thymosin therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Hunan Cancer Hospital China 2020-03-16 2020-05-16 ChiCTR2000031023, ChiMCTR2000003138 Phase Not Applicable Recruiting 1 2 Months 320 Yang Jinfeng 2020-03-30
Remedy of human coronavirus infection with genetic nanocomposit drug Coronavirus disease 19 infection, Viral pneumonia genetical nanocomposit drug (RNA Biotechnology) alone RNA biotechnology Iran 2020-03-22 IR.IAU.KHUISF.REC.1399.001, IRCT20200321046828N1 Phase 1/Phase 2 Clinical No longer recruiting 1 30 Dr Mahdi Khozaei, Mr Eng Montazeri, ِDr Mahdi Khozaei 2020-03-31
Use of Ascorbic Acid in Patients With COVID-19 Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia conventional therapy alone, vitamin C alone University of Palermo Italy 2020-03-13 2021-03-13 3143, NCT04323514 Phase Not Applicable Recruiting 1 12 Months 500 Salvatore Corrao, Salvatore Corrao, MD 2020-03-30
Colchicine Efficacy in COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia colchicine alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Azienda Ospedaliero-Universitaria di Parma Italy 2020-04-01 2020-06-30 COLCOVID01, NCT04322565 Phase 2 Clinical Not yet recruiting 1 3 Months 100 Lucio Manenti, MD, Umberto Maggiore, MD 2020-03-30
A clinical trial of opaganib (Yeliva) alone and in combination with other compounds, for the treatment of COVID-19 Coronavirus disease 19 infection opaganib alone Dihydroceramide delta 4 desaturase inhibitor, Sphingosine kinase 2 inhibitor RedHill Biopharma Ltd Phase Not Applicable Planned 0 2020-03-27
An expanded access protocol to study potential benefit of nebulized treatment with Ampion in patients with SARS-Cov-2 (COVID-19) induced Acute Respiratory Distress Syndrome (ARDS) Coronavirus disease 19 infection, Respiratory distress syndrome Ampion (intranasal, inflammation), Ampio/DMI Biosciences alone Stem cell antigen-1 inhibitor Ampio Pharmaceuticals Inc US Phase Not Applicable Planned 0 2020-03-30
Coalition-I: Safety and Efficacy of Hydroxychloroquine Associated With Azithromycin in SARS-Cov-2 Virus Coronavirus disease 19 infection hydroxychloroquine alone, azithromycin plus hydroxychloroquine Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital do Coracao Brazilian Research In Intensive Care Network, EMS SA, Hospital Of Syrian Lebanese Itatiba S/C Ltd, Sociedade Beneficente Israelita Brasileira Hospital Albert Einsten Brazil 2020-04-06 2020-08-30 BRAZIL COVID COALITION I TRIAL, Coalition-I, NCT04322123 Phase 3 Clinical Not yet recruiting 33 4 Months 630 Alexandre Biasi, PhD, Antônio Paulo Nassar, Cassia Righy, Cintia Grion, Cristina Amendola, Emerson Silva, Eraldo Lucio, Felipe Dal Pizzol, Fernando Ramos, Fernando Zampieri, PhD, Flavia Machado, Flávio Freitas, Fábio Lacerda, Glauco Westphal, Hugo Urbano, Israel Maia, Israel Maia, PhD, Jorge Luiz Paranhos, José Andrade Neto, João Manoel Silva Junior, Luciazo Azevedo, Luiz Dalfior Junior, Lúcio Oliveira Junior, Marco Antonio Guedes, Miqueias Silva, Neymar Oliveira, Niklas Soderberg, Otavio Berwanger, Rodrigo Biondi, Rodrigo Cruvinel, Thiago Lisboa, Viviane Veiga, Wilson José Lovato, PhD 2020-03-30
A clinical study to assess antiviral activity of Elpida in the treatment of patients with COVID-19 Coronavirus disease 19 infection elsulfavirine alone HIV-1 reverse transcriptase inhibitor, Non-nucleoside reverse transcriptase inhibitor Viriom Inc Ministry of Health and Social Development of the Russian Federation, The Chinese Centre for Disease Control and Prevention Phase Not Applicable Planned 0 2020-03-27
Efficacy of Natural Honey Treatment in Patients With Novel Coronavirus Coronavirus disease 19 infection standard care alone, Variable regimens including Arbidol , azithromycin , chloroquine , hydroxychloroquine , lopinavir + ritonavir , natural honey , oseltamivir Exo-alpha sialidase inhibitor, HIV protease inhibitor Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Misr University for Science and Technology Egypt 2020-03-25 2020-05-10 MUST23032020, NCT04323345 Phase 3 Clinical Not yet recruiting 1 1 Month 1000 Mahmoud Ahmed Tantawy, Mahmoud Tantawy, MD 2020-03-30
A clinical study to assess CoV-2 mRNA vaccine for the potential treatment of SARS-CoV-2 (2019-nCoV) Coronavirus disease 19 infection cross-strain mRNA vaccine (TriMix/intranasal, coronavirus infection), eTheRNA/EpiVax/ReproCELL alone CD40 ligand receptor agonist, CD70 antigen modulator, TLR-4 agonist eTheRNA immunotherapies NV EpiVax Inc, Nexelis, ReproCELL Inc, University of Antwerp Phase Not Applicable Planned 0 2020-03-31
MP-C19: Efficacy of Methylprednisolone for Patients With COVID-19 Severe Acute Respiratory Syndrome Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia ECMO alone, antiviral therapy alone, empiric antibiotic therapy alone, mechanical ventilation alone, oxygen therapy alone, standard care alone, vitamins alone, chloroquine plus methylprednisolone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) L'Universita Degli Studi di Trieste Italy 2020-03-23 2020-05-30 MP-19 023_2020, MP-C19, NCT04323592 Phase 2/Phase 3 Clinical Recruiting 1 2 Months 104 Francesco Salton, MD, Francesco confalonieri, MD, Marco Confalonieri, MD, marco confalonieri, MD 2020-03-30
Evaluation the Efficacy and Safety of Tocilizumab in COVID-19 Coronavirus disease 19 infection Variable regimens including hydroxychloroquine , lopinavir + ritonavir , oseltamivir , tocilizumab (intravenous), Roche/Chugai Exo-alpha sialidase inhibitor, HIV protease inhibitor, IL-6 receptor antagonist, IL-6 receptor modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shaheed Beheshti Medical University Iran 2020-03-11 IR.SBMU.NRITLD.REC.1399.002, IRCT20151227025726N13 Phase 2 Clinical Recruiting 1 40 Ali Saffaei, Farzaneh Dastan, Payam Tabarsi 2020-03-30
SOLIDARITY: Public health emergency SOLIDARITY trial of treatments for COVID-19 infection in hospitalized patients Coronavirus disease 19 infection, SARS coronavirus infection chloroquine alone, hydroxychloroquine alone, lopinavir + ritonavir alone, remdesivir alone, standard of care alone, interferon-beta plus lopinavir + ritonavir HIV protease inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) World Health Organization Iran, Brazil, Spain, Qatar, South Africa, Peru, Indonesia, Switzerland, Canada, Thailand, Germany, Argentina, Norway 2020-03-01 2021-03-25 0003361, ISRCTN83971151, SOLIDARITY Phase 3 Clinical Recruiting 13 12 Months Dr MariaHenaoRestrepo, Dr Moorthy, Dr Preziosi 2020-03-30
ProPAC-COVID: Proactive Prophylaxis With Azithromycin and Chloroquine in Hospitalized Patients With COVID-19 Coronavirus disease 19 infection standard care alone, azithromycin plus hydroxychloroquine Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chronic Obstructive Pulmonary Disease Trial Network 2020-04-01 2021-03-31 KRONLUNGESYG_COVID_19_PROTOKOL, NCT04322396, ProPAC-COVID Phase 4 Clinical Not yet recruiting 0 12 Months 226 Jens-Ulrik Stæhr Jensen, MD, PhD 2020-03-30
CloroCOVID19: Chloroquine Diphosphate for the Treatment of Severe Acute Respiratory Syndrome Secondary to SARS-CoV2 Coronavirus disease 19 infection, SARS coronavirus infection chloroquine diphosphate alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Foundation of Tropical Medicine Doctor Heitor Vieira Dourado Brazil 2020-03-23 2020-08-31 CAAE: 30152620.1.0000.0005, CloroCOVID19, NCT04323527 Phase 2b Clinical Recruiting 1 5 Months 440 Fernando Val, PhD, Marcus Lacerda, PhD, Mayla Borba, MD 2020-03-31
ONSCOVID19: Anti-inflammatory/Antioxidant Oral Nutrition Supplementation in COVID-19 Coronavirus disease 19 infection Oxepa alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) King Saud University Saudi Arabia 2020-04-01 2020-10-30 NCT04323228, ONSCOVID19, ONS_COVID-19 Phase 4 Clinical Not yet recruiting 1 6 Months 30 Mahmoud Abulmeaty, Mahmoud M.A. Abulmeaty, M.D., FACN 2020-03-30
A clinical trial of Assurance AB COVID-19 IgM/IgG Rapid Antibody Test to detect the presence of IgM and/or IgG antibodies to the SARS-CoV-2 virus Coronavirus disease 19 infection, SARS coronavirus infection Assurance AB alone Predictive Technology Group Inc US Phase Not Applicable Status not specified 0 2020-03-30
Study of the metformin effect on the survival and recovery rate of COVID-19 patients Coronavirus disease 19 infection metformin hydrochloride alone, standard therapy alone AMP activated protein kinase stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tabriz University of Medical Sciences Iran 2020-03-20 IR.TBZMED.REC.1398.1309, IRCT20160310026998N10 Phase 3 Clinical Recruiting 1 200 Ghaffary, Saba Ghaffary, saba ghaffary 2020-03-30
A phase III, large-scale clinical trial to evaluate the effectiveness of VPM-1002 against an infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in elderly people and healthcare workers Coronavirus disease 19 infection, SARS coronavirus infection VPM-1002 alone Listeriolysin stimulator Max-Planck Gesellschaft zur Förderung Der Wissenschaften eV Germany Phase 3 Clinical Planned 1 2020-03-27
SARPAC: Sargramostim in Patients With Acute Hypoxic Respiratory Failure Due to COVID-19 Coronavirus disease 19 infection, Hypoxia, Respiratory failure sargramostim alone CSF-1 agonist, GM-CSF receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Partner Therapeutics Inc, Universitair Ziekenhuis Gent VIB Belgium, Italy, Spain, Germany 2020-03-23 2020-12-31 2020-001254-22, NCT04326920, SARPAC Phase 4 Clinical Recruiting 6 9 Months 80 Anja Delporte, Bart Lambrecht, Bart Lambrecht, MD PhD, HIRUZ CTU, Stefaan Vandecasteele, MD Phd 2020-04-03
A Phase I/II clinical trial of human monoclonal antibody for potential treatment of SARS-CoV-2 (COVID-19) Coronavirus disease 19 infection, SARS coronavirus infection human mAbs (COVID-19/ SARS/ MERS), Vir Biotechnology/ NIAID alone Vir Biotechnology Inc Phase 1/Phase 2 Clinical Planned 0 2020-03-27
Clinical study of human NK cells and MSCs transplantation for severe novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia SNCP treatment alone, natural killer (NK) cells plus umbilical cord derived mesenchymal stem cells (UC-MSCs) Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Jiangxi Chest Hospital, Jiangxi Mayo Biotechnologies Co LTD, Second Hospital Affiliated to Nanchang University Science and Technology Agency of Jiangxi province China 2020-03-01 2020-08-31 ChiCTR2000030944 Phase 1 Clinical Not yet recruiting 2 6 Months 20 Duan Zhongxin, Ye Xiaoqun 2020-03-30
Venous thrombosis risk of novel coronavirus pneumonia (COVID-19) patients: A prospective study Coronavirus disease 19 infection, Phlebothrombosis, Viral pneumonia Shandong Provincial Hospital China 2020-03-25 2020-05-31 ChiCTR2000030943 Phase Not Applicable Not yet recruiting 1 2 Months 200 Jiang Shujuan, Wei Yuanhui 2020-03-30
Acute Encephalopathy in Critically Ill Patients With SARS-Cov-2 Infection Brain disease, Coronavirus disease 19 infection, SARS coronavirus infection clinical examination alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ictal Group France 2020-03-23 2020-12-31 NCT04320472, NEURO-COVID-19 Phase Not Applicable Recruiting 1 9 Months 250 Stephane LEGRIEL, MD, PhD 2020-04-02
Risk Factors for Community- and Workplace Transmission of COVID-19 Coronavirus disease 19 infection biological sampling alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Oslo University Hospital Age Labs AS Norway 2020-03-27 2030-03-20 NCT04320732, REK-124170 Phase Not Applicable Recruiting 2 119 Months 50000 Arne Soraas, MD, PhD, Arne Søraas, PhD, Arne Vasli Lund Soraas, John A Dahl, PhD, John Arne Dahl, PhD 2020-04-01
The Efficacy of Different Anti-viral Drugs in (Severe Acute Respiratory Syndrome-Corona Virus-2) SARS-CoV-2 Coronavirus disease 19 infection hydroxychloroquine alone, remdesivir alone, standard of care alone, hydroxychloroquine plus remdesivir RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Oslo University Hospital Norway 2020-03-26 2020-11-30 118684, NCT04321616 Phase 2/Phase 3 Clinical Not yet recruiting 2 8 Months 700 Andreas Barratt-Due, MD, PhD, Anne Margarita Dyrhol Riise, MD, Professor, Inge Christoffer Olsen, PhD, Katerina Nezvalova-Henriksen, Pharm D, PhD, Marius Troseid, MD, PhD, Paul Aukrust, MD, Professor, Trine Kasine, MD 2020-04-06
Non-contact Endoscopy at Covid-19 Outbreak Coronavirus disease 19 infection magnetically-controlled capsule endoscopy (MCE) system (Ankon Technologies) alone, non-contact endoscopy alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Changhai Hospital China 2020-03-16 2020-03-16 NCMCE1, NCT04320953 Phase Not Applicable Completed 1 1 Zhuan Liao, MD 2020-03-27
A medical records based study for clinical features and prognosis of severe patients with novel coronavirus pneumonia (COVID-19) in Huanggan, Hubei in Huanggang Coronavirus disease 19 infection, Viral pneumonia Hunan Provincial People's Hospital China 2020-03-15 2020-12-15 ChiCTR2000030941 Phase Not Applicable Recruiting 1 9 Months 200 Yi-Yin Chen 2020-03-27
Metabolic abnormalities and rearrangement reversal treatment in COVID-19 infection Coronavirus disease 19 infection, Viral pneumonia compound amino acid treatment alone, routine treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) The Third Affiliated Hospital of Sun Yat-Sen University China 2020-04-01 2020-04-01 ChiCTR2000031271 Phase 1 Clinical Not yet recruiting 1 80 Zhuang-Gui Chen 2020-03-27
A RCT for Hua-Shi Bai-Du granules in patients with novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Hua-Shi Bai-Du granules alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Guangdong Provincial Hospital of Chinese Medicine China 2020-03-20 2020-05-31 ChiCTR2000030988, ChiMCTR2000003142 Phase Not Applicable Not yet recruiting 1 2 Months 204 Jianwen Guo, Zhongde Zhang 2020-03-27
CORIPREV-LR: COVID-19 Ring-based Prevention Trial With Lopinavir/Ritonavir Coronavirus disease 19 infection lopinavir + ritonavir alone HIV protease inhibitor Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) St Michaels Hospital Canada 2020-03-30 2022-03-31 CORIPREV-1, CORIPREV-LR, NCT04321174 Phase 3 Clinical Not yet recruiting 3 24 Months 1220 Adrienne Chan, MD MPH FRCPC, Alex Schnubb, Attia Qamar, BEng, Darrell Tan, MD FRCPC PhD 2020-03-27
A Randomized Controlled Trial for Favipiravir Tablets Combine With Chloroquine Phosphate in the Treatment of Novel Coronavirus Pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia favipiravir alone, chloroquine phosphate plus favipiravir RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Beijing Chao-Yang Hospital China 2020-03-05 2020-06-25 ChiCTR2000030987 Phase 2/Phase 3 Clinical Recruiting 1 3 Months 150 Shumin Wang, Zhaohui Tong 2020-03-27
Study for 'Bai-Du Duan Fang' application on the acupoint in the treatment of general type novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Bai-Du Duan Fang application alone, Western medicine alone, acupoint application (Zusanli + Feishu) alone, routine nursing alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Longhua Hospital Shanghai University of TCM China 2020-02-01 2020-06-30 ChiCTR2000030940, ChiMCTR2000003152 Phase Not Applicable Not yet recruiting 1 5 Months 76 Wei Lu 2020-03-27
Preliminary evaluation of the safety and efficacy of oral LL-37 antiviral peptide (CAS-001) in the treatment of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia CAS-001 alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chinese PLA General Hospital China 2020-03-16 2020-10-01 ChiCTR2000030939 Phase 0 Clinical Recruiting 2 6 Months 10 Gang Sun 2020-03-27
Correlation of T-lymphocytes level and clinical severity in novel coronavirus pneumonia (COVID-19) patients: a medical records based retrospective study Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The Third People’s Hospital of Shenzhen China 2020-03-20 ChiCTR2000030986 Phase Not Applicable Recruiting 1 200 GAO Hong, WU Qiang 2020-03-27
CamoCO-19: The Impact of Camostat Mesilate on COVID-19 Infection Coronavirus disease 19 infection camostat mesylate alone Serine protease inhibitor, Trypsin inhibitor Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Aarhus University Denmark 2020-03-31 2021-05-01 2020-001200-42, CamoCO-19, NCT04321096 Phase 2a Clinical Not yet recruiting 3 13 Months 180 Jacob Bodilsen, Lars Ostergaard, Professor, Ole S Soegaard, MD, PhD, Ole S Sogaard, MD PhD, Ole S Søgaard, MD, PhD 2020-03-27
Clinical investigation and reseach on TCM syndrome of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin Haihe Hospital China 2020-02-28 2021-06-30 ChiCTR2000030938, ChiMCTR2000003151 Phase 0 Clinical Recruiting 2 16 Months 160 Sun Hongyuan 2020-03-27
Psychological Responses of Medical Staff during the Metaphase of Novel Coronavirus pneumonia (COVID-19) Outbreak in Hubei, China Anxiety disorder, Coronavirus disease 19 infection, Depression, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Asian Ancestry Renmin Hospital of Wuhan University China 2020-03-04 2020-03-09 ChiCTR2000030985 Phase Not Applicable No longer recruiting 1 1300 Wenqin Song, Zhongyuan Xia 2020-03-26
A randomized, open-label, controlled trial for Gu-Shen Ding-Chuan-Wan in the treatment of patients with novel coronavirus pneumonia (COVID-19) at recovery phase with Fei-Pi-Qi-Xu Zhen Coronavirus disease 19 infection, Viral pneumonia Gu-Shen Ding-Chuan-Wan alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The First Affiliated Hospital of Guangzhou Medical College Guangzhou Baiyunshan Jingxiutang Pharmaceutical Co Ltd China 2020-03-19 2020-08-30 ChiCTR2000030937, ChiMCTR2000003150 Phase 4 Clinical Recruiting 6 5 Months 144 Li Shi-yue, Zeng Li-jie 2020-03-30
A real-world study for the Chinese medicines 'Xinguan 2' and 'Xinguan 3' in the treatment of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia regular treatment alone, Jingfanghuopujiedu Mixture (Xinguan No. 3) plus Yinqiaohuopu Tuire Mixture (Xinguan No. 2) Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) The Affiliated Hospital of Chengdu University of Traditional Chinese Medicine China 2020-03-10 2020-05-10 ChiCTR2000030936 Phase 3 Clinical Recruiting 15 2 Months 2840 Peiyang Gao, Xiaolan Kong 2020-03-27
A medical records based study for clinical application of extracorporeal membrane oxygenation in the treatment of severe respiratory failure patients with novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Beijing Chao-Yang Hospital, Capital Medical University China 2020-02-01 2020-04-30 ChiCTR2000030947 Phase Not Applicable Recruiting 1 3 Months 34 Xuyan Li, Zhaohui Tong 2020-03-27
Study for the impact on fetus and neonates of vertical transmission of 2019-nCoV Coronavirus disease 19 infection Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Union Hospital Tongji Medical School Huazhong University Of Science & Technology Huazhong University of Science and Technology China 2020-02-01 2020-08-31 ChiCTR2000031140 Phase 0 Clinical Recruiting 1 7 Months 300 CHEN Hui 2020-03-27
A Platform for Rapid Immuno-detection and Emergency Vaccine Development of Novel Coronavirus (2019-COV) Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia Fifth Affiliated Hospital, Sun Yat-Sen University China 2020-03-01 2021-02-28 ChiCTR2000030934 Phase Not Applicable Recruiting 1 12 Months 90 Tian Lin 2020-03-27
Safety and Effectiveness of Human embryonic stem cell-derived M cells (CAStem) for Pulmonary Fibrosis Correlated with novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Pulmonary fibrosis, Viral pneumonia Human embryonic stem cell-derived M cells (CAStem) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chinese Academy of Sciences, Wuhan Jinyintan Hospital Ministry of Science and Technology of the People´s Republic of China China 2020-03-20 2021-03-19 ChiCTR2000031139 Phase 0 Clinical Recruiting 1 12 Months 20 Liu Ying, Zhang Dingyu 2020-03-27
Coalition Covid-19 Brasil II: Safety and Efficacy of Hydroxychloroquine Associated With Azithromycin in SARS-CoV2 Virus Coronavirus disease 19 infection azithromycin plus hydroxychloroquine Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sociedade Beneficente Israelita Brasileira Hospital Albert Einsten Brazilian Research In Intensive Care Network, Cristalia, EMS SA, Hospital Of Syrian Lebanese Itatiba S/C Ltd, Hospital do Coracao Brazil 2020-03-28 2020-08-30 30155020.5.1001.0071, ALLIANCE COVID-19 BRASIL II, CAAE, Coalition Covid-19 Brasil II, NCT04321278 Phase 3 Clinical Recruiting 21 5 Months 440 ARO-HIAE Academic Research Organization HIAE, Adrian PM Kormann, MD, Alexandre M Soeiro, MD, Ary Serpa-Neto, PhD, Carla MG Godoy, MD, Cintia MC Grion, MD, Cláudio Galvão, PhD, Cristina P Amendola, MD, Eraldo A Lucio, MD, Fabio H Lacerda, MD, Felipe Dal Pizzol, MD, Fernado G Zampieri, MD, Fernando C Neuenschwander, MD, Fernando G Zampieri, MD, Flavia R Machado, MD, Flavio GR Freitas, MD, Frederico TC DallOrto, MD, Guilherme Schettino, PhD, Henrique Fonseca, PhD, Israel S Maia, MD, Jorge LR Paranhos, MD, Leonardo R Ferraz, PhD, Luciano CP Azevedo, MD, Luiz V Rizzo, PhD, Marco AV Guedes, MD, Maria SM Paiva, MD, Mauro E Hernandes, MD, Otávio Berwanger, PhD, Remo Furtado, PhD, Rodrigo C Figueiredo, MD, Rodrigo S Biondi, MD, Thiago C Lisboa, MD, Thiago Correa, PhD, Viviane C Veiga, MD, Wilson J Lovato, MD, Ótávio Berwanger, PhD 2020-04-02
Psychological Support for Diagnosed Patients with novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia cognitive behavioral therapy alone, psychological support alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ningbo Kangning Hospital China 2020-03-24 2022-03-23 ChiCTR2000031090 Phase Not Applicable Not yet recruiting 1 24 Months 60 Haihang Yu, Xiaoli Liu 2020-03-27
A prognosis study of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Xiangyang First People's Hospital China 2020-02-09 2022-02-09 ChiCTR2000031088 Phase Not Applicable Recruiting 1 24 Months 314 Huang Guoxin, Pei Bin 2020-03-27
Prospective exploratory clinical research on the efficacy and safety of pirfenidone capsules in the treatment of severe novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia pirfenidone alone PDGF receptor antagonist, TGF beta receptor antagonist, p38 MAP kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The Third Xiangya Hospital of Central South University China 2020-03-01 2020-12-31 ChiCTR2000031138 Phase 0 Clinical Recruiting 2 10 Months 40 Meng Jie 2020-03-27
Efficacy and safety of aerosol inhalation of vMIP in the treatment of novel coronavirus pneumonia (COVID-19): a single-arm clinical trial Coronavirus disease 19 infection, Viral pneumonia conventional standardized treatment alone, vMIP alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Union Hospital Tongji Medical School Huazhong University Of Science & Technology Guangzhou Suyuan Biotechnology China 2020-02-07 2020-07-30 ChiCTR2000029636 Phase 0 Clinical Recruiting 1 5 Months 40 Hu bo, Kuang fa-hao, Li wei, Sun han-xiao 2020-03-27
Effectiveness of 'Liu-Zi-Jue' combined with respiratory muscle training for respiratory function in novel coronavirus pneumonia (COVID-19) patients: a randomized, controlled trial Coronavirus disease 19 infection, Viral pneumonia Liu-Zi-Jue exercise alone, respiratory muscle training alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Jiangxi University of Science and Technology, The First Affiliated Hospital of Nanchang University China 2020-02-29 2020-12-31 ChiCTR2000030933 Phase 0 Clinical Not yet recruiting 3 10 Months 108 Feng Zhen, Li Moyi 2020-03-27
Correlation between virological negative conversion and clinical factors and prognosis in patients with novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Anqing Municipal Hospital China 2020-02-01 2020-06-30 ChiCTR2000030932 Phase Not Applicable Recruiting 1 5 Months 100 Changqing Hu, Changtai Wang 2020-03-27
Psychosocial Effects Of Coronavirus Disease 2019 (COVID-19) Amongst Healthcare Providers In Johor Coronavirus disease 19 infection, Psychiatric disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Permai Malaysia 2020-02-17 2020-08-31 53218, NMRR-20-213-53218 Phase Not Applicable Recruiting 5 6 Months Dr NURUL NADIA BINTI HASBOLLAH, Suhaila Mohd Som 2020-03-27
A Medical Records Based Study for Clinical Characteristic and Outcomes of Hospitalized Patients With Novel Coronavirus Pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Huizhou Municipal Central Hospital, Guangdong China 2020-03-23 2020-05-22 ChiCTR2000030931 Phase Not Applicable Not yet recruiting 1 2 Months 60 Huang Hui 2020-03-27
COVID-19 detection by VOC: Early Detection of Novel Coronavirus Pneumonia (COVID-19) Based on a Novel High-Throughput Mass Spectrometry Analysis With Exhaled Breath Coronavirus disease 19 infection, Viral pneumonia Mass Spectrometry Analysis alone Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shenzhen Burui Biotechnology Co., Ltd, The Third People’s Hospital of Shenzhen China 2020-03-01 2023-03-31 COVID-19 detection by VOC, ChiCTR2000029695, NCP-VOC Phase 0 Clinical Not yet recruiting 1 37 Months Deng Guofang, Fu Liang 2020-03-27
A Multicenter, Randomized, Parallel Controlled Clinical Study of Hydrogen-Oxygen Nebulizer to Improve the Symptoms of Patients With Novel Coronavirus Pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia hydrogen-oxygen nebulize alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The First Affiliated Hospital of Guangzhou Medical College Shanghai Asclepius Meditec Co., Ltd China 2020-02-01 2021-08-31 ChiCTR2000029739 Phase Not Applicable Recruiting 3 19 Months 440 Changsheng Zhao, Nanshan Zhong, Zeguang Zheng 2020-03-27
Risks of Death and Severe cases in Patients with 2019 Novel Coronavirus Pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Tongji Hospital National Natural Science Foundation of China China 2020-01-26 2020-03-31 ChiCTR2000029735 Phase Not Applicable Recruiting 1 2 Months 500 Min Xie, Xiaochen Li 2020-03-27
BEAT19: Behavior, Environment And Treatments for COVID-19 Coronavirus disease 19 infection, SARS coronavirus infection daily diary survey alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) xCures inc Cancer Commons, Genetic Alliance, LunaPBC, RedCap LLC US 2020-03-21 2022-03-20 BEAT19, NCT04321811, XC-PCOR-COVID19 Phase Not Applicable Recruiting 0 24 Months 100000 BEAT19.org, Mark Shapiro 2020-04-03
A Medical Records Based Study for the Effectiveness of Extracorporeal Membrane Oxygenation in Patients with Severe Novel Coronavirus Pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia extracorporeal membrane oxygenation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Zhangnan Hospital China 2020-01-11 2020-12-28 ChiCTR2000029949 Phase Not Applicable Not yet recruiting 1 11 Months 40 Xian-Long, Zhou, Yan, Zhao 2020-03-30
Impact of vitamin D deficiency on prognosis of patients with novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia, Vitamin D deficiency Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) West China Hospital Science & Technology Department of Sichuan Province China 2020-02-10 2020-04-10 ChiCTR2000029732 Phase 0 Clinical Not yet recruiting 4 2 Months 156 Jun Guo 2020-03-27
A randomized, double-blind, parallel-controlled trial to evaluate the efficacy and safety of anti-SARS-CoV-2 virus inactivated plasma in the treatment of severe novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia anti-SARS-CoV-2 virus inactivated plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Renmin Hospital of Wuhan University, Sinopharm Wuhan Blood Products Co., Ltd. China 2020-03-17 2020-06-16 ChiCTR2000030929 Phase 2 Clinical Not yet recruiting 1 3 Months 60 Binghong Zhang, Lianghao Zhang 2020-03-27
A phase I clinical trial of COVID-HIG for potential treatment and prevention of coronavirus disease (COVID-19) Coronavirus disease 19 infection COVID-HIG alone Emergent BioSolutions Inc 2020-09-30 Phase 1 Clinical Planned 0 2020-03-26
A multicenter study for efficacy of intelligent psychosomatic adjustment system intervention in the treatment of novel coronavirus pneumonia (COVID-19) patients with mild to moderate anxiety and depression Anxiety disorder, Coronavirus disease 19 infection, Depression, Viral pneumonia intelligent psychosomatic adjustment system intervention therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) The First Hospital of Shanxi Medical University China 2020-02-01 2022-02-01 ChiCTR2000030084 Phase 0 Clinical Recruiting 4 24 Months 180 Liu Zhifen, Xu Yong 2020-03-27
Clinical study for the diagnostic value of pulmonary ultrasound for novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Union Hospital Tongji Medical School Huazhong University Of Science & Technology National Natural Science Foundation of China China 2020-02-12 2023-02-12 ChiCTR2000030087 Phase 0 Clinical Recruiting 1 36 Months 800 Li Zhang, Mingxing Xie 2020-03-27
A single-arm study for evaluation of integrated traditional Chinese and western medicine in the treatment of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia TCM syndrome differentiation treatment alone, Western medicine treatment alone Henan University of Chinese Medicine China 2020-02-01 2020-12-31 ChiCTR2000029436, ChiMCTR2000002952 Phase 0 Clinical Not yet recruiting 5 11 Months Li Jiansheng, Li Suyun, Xie Yang 2020-03-27
A Prospective, Randomized, Controlled Trial for Home Exercise Prescription Intervention During Epidemic of Novel Coronary Pneumonia (COVID-19) in College Students Coronavirus disease 19 infection, Viral pneumonia exercise prescription therapy alone Adolescents (13-17 yrs), Young Adults (18-44 yrs) West China Hospital China 2020-02-22 2020-03-22 ChiCTR2000030090 Phase Not Applicable Not yet recruiting 1 1 Month 400 LIU YAN, XIONG YAN 2020-03-27
Cancelled due to lack of patient Medical records based study for epidemiological and clinical characteristics of 2019 novel coronavirus pneumonia (COVID-19) in Chongqing Coronavirus disease 19 infection, Viral pneumonia Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Chongqing Three Gorges Central Hospital China 2020-02-17 2020CDJYGRH-YJ03, ChiCTR2000029952 Phase Not Applicable No longer recruiting 1 Kaihu Xiao 2020-03-26
A prospective, randomized, controlled trial for the home exercise prescription intervention in nursing students during epidemic of novel coronary pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia exercise prescription therapy alone West China Hospital China 2020-02-22 2020-03-22 ChiCTR2000030091 Phase Not Applicable Not yet recruiting 1 1 Month 200 LIU YAN, XIONG YAN 2020-03-26
Evaluation of myocardial injury of novel coronavirus pneumonia (COVID-19) assessed by multimodal MRI imaging Coronavirus disease 19 infection, Viral pneumonia multimodal MRI imaging alone West China Second University Hospital China 2020-03-01 ChiCTR2000029955 Phase 0 Clinical Not yet recruiting 1 100 Ying-kun Guo 2020-03-30
Assessment of cardiac function in patients with Novel Coronavirus Pneumonia (COVID-19) by echocardiography and its new techniques Coronavirus disease 19 infection, Heart disease, Viral pneumonia Union Hospital Tongji Medical School Huazhong University Of Science & Technology National Natural Science Foundation of China China 2020-02-12 2022-02-12 ChiCTR2000030092 Phase 0 Clinical Recruiting 1 24 Months 800 Li Zhang, Mingxing Xie 2020-03-30
Pandemic Response Network Coronavirus disease 19 infection Duke University US 2020-03-31 2021-12-31 NCT04320862, PRO00105189 Phase Not Applicable Not yet recruiting 0 21 Months 200000 Becky Smith, MD, Devdutta Sangvai, M.D., Manesh Patel, M.D., Mark Sendak, M.D., Mark Sendak, MD, MPP, Raquel Bartz, M.D. 2020-04-01
COVACTA: A Study to Evaluate the Safety and Efficacy of Tocilizumab in Patients With Severe COVID-19 Pneumonia Coronavirus disease 19 infection standard of care alone, tocilizumab (intravenous), Roche/Chugai alone IL-6 receptor antagonist, IL-6 receptor modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Genentech Inc, Roche Holding AG Biomedical Advanced Research and Development Authority (BARDA) US 2020-03-19 2021-09-30 2020-001154-22, COVACTA, NCT04320615, WA42380 Phase 3 Clinical Recruiting 0 18 Months 330 Clinical Trials 2020-03-31
COVIP: Outcomes and Prognostic Factors in COVID-19 Coronavirus disease 19 infection, SARS coronavirus infection Aged Adults (65-79 yrs), Elderly Adults (80 and over) Heinrich Heine Universitat Dusseldorf Germany 2020-03-19 2020-12-31 20-004, COVIP, NCT04321265 Phase Not Applicable Recruiting 1 9 Months 4000 Christian Jung, MD, Christian Jung, MD, PhD, Dr. Dr. Christian Jung, Rabea Wagstaff, MA, Raphael Bruno, MD 2020-03-28
A Pre-exposure, prophylaxis, randomized, placebo-controlled trial in front line health care workers including emergency room staff and ICU staff for the prevention of COVID-19 Coronavirus disease 19 infection hydroxychloroquine, Apotex Inc alone The University Health Network, Unity Health Toronto Apotex Inc Phase Not Applicable Status not specified 0 2020-03-30
A single-arm study for combination of traditional Chinese and Western Medicine in the treatment of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia traditional Chinese and Western Medicine alone Hubei Provincial Department of Education China 2020-02-01 2020-12-01 ChiCTR2000029437, ChiMCTR2000002953 Phase Not Applicable Not yet recruiting 1 10 Months 300 Xia Wenguang, An Changqing, Zhang Boli, Zhang Junhua 2020-03-27
Study for application of simplified cognitive-behavioral therapy for related emergency psychological stress reaction of medical providers working in the position of treatment and control of novel coronavirus pneumonia (COVID-19) Acute stress disorder, Coronavirus disease 19 infection, Viral pneumonia simplify cognitive behavior therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) The Second Hospital of Shanxi Medical University China 2020-02-01 2021-03-31 ChiCTR2000030093 Phase Not Applicable Not yet recruiting 1 14 Months 60 Tian Feng 2020-03-27
COVID CT: Beaumont Quantitative Lung Function Imaging to Characterize Patients With SARS-COV 2 Coronavirus disease 19 infection, SARS coronavirus infection computerized tomography alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) William Beaumont Hospitals US 2020-04-30 2022-03-31 2020-087, COVID CT, NCT04320511 Phase Not Applicable Not yet recruiting 0 23 Months 25 Girish B Nair, MD, Joanne Gondert, RN, BSN 2020-04-01
A randomized controlled trial of integrated TCM and Western Medicine in the treatment of severe novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia TCM standard decoction therapy alone, basic western medical therapy alone Beijing Hospital of Traditional Chinese Medicine affiliated to Capital Medical University China 2020-02-01 2021-12-31 ChiCTR2000029438, ChiMCTR2000002954 Phase 0 Clinical Not yet recruiting 2 23 Months 120 WANG YUGUANG, LI XUCHENG, ZHANG BOLI, ZHANG JUNHUA 2020-03-27
Clinical study for the integration of traditional Chinese and western medicine in the treatment of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Western medicine basic treatment alone, traditional Chinese medicine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shanghai Pulmonary Hospital Tongji University China 2020-02-17 2020-10-31 ChiCTR2000029790, ChiMCTR2000003009 Phase Not Applicable Recruiting 1 8 Months 120 Lixin Wang 2020-03-30
Clinical study of a novel high sensitivity nucleic acid assay for novel coronavirus pneumonia (COVID-19) based on CRISPR-cas protein Coronavirus disease 19 infection, Viral pneumonia RT-PCR test alone Shenzhen Second People's Hospital China 2020-02-16 2020-03-20 ChiCTR2000029810 Phase Not Applicable Recruiting 1 1 Month 1300 Weiren Huang 2020-03-27
Combination of traditional Chinese medicine and western medicine in the treatment of common type novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia TCM standard decoction therapy alone, basic western medical therapy alone Beijing Hospital of Traditional Chinese Medicine affiliated to Capital Medical University China 2020-02-01 2021-12-31 ChiCTR2000029439, ChiMCTR2000002955 Phase 0 Clinical Not yet recruiting 2 23 Months 120 WANG YUGUANG, LI XUCHENG, ZHANG BOLI, ZHANG JUNHUA 2020-03-27
A multicenter, randomized, open and controlled trial for the efficacy and safety of Kang-Bing-Du granules in the treatment of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Kangbingdu granules alone, routine treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Union Hospital Tongji Medical School Huazhong University Of Science & Technology Sichuan Guangda Pharmacy Co., Ltd. China 2020-02-10 2020-06-30 ChiCTR2000029781, ChiMCTR2000003005 Phase 4 Clinical Recruiting 5 4 Months 160 Hong Sun, Xin Zheng 2020-04-01
Cancelled by the investigator Clinical Study for Anti-aging Active Freeze-dried Powder Granules in the Treatment of Acute Novel Coronavirus Pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Anti-aging Active Freeze-dried Powder Granules alone, Conventional treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Guangzhou reborn health management consultancy co., LTD China 2020-02-20 2021-02-20 ChiCTR2000029811 Phase 0 Clinical Not yet recruiting 1 12 Months 60 Chao Xu 2020-03-27
A Medical Records Based Study for Construction and Analysis of Diagnosis Predictive Model of Novel Coronavirus Pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chongqing Liangjiang New Area first people's Hospital, Dianjiang County People's Hospital of Chongqing China 2020-02-21 2020-08-21 ChiCTR2000030042 Phase Not Applicable Recruiting 2 6 Months 240 Chen Hao 2020-03-27
Study for clinical characteristics and distribution of TCM syndrome of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Henan University of Chinese Medicine China 2020-02-01 2020-12-31 ChiCTR2000029462, ChiMCTR2000002960 Phase Not Applicable Not yet recruiting 8 11 Months 200 Li Jiansheng, Xie Yang 2020-03-27
Clinical study for the changes in mental state of medical staff in the department of radiotherapy in a comprehensive tertiary hospital in Zhejiang Province during the epidemic of novel coronavirus infection (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Zhejiang Provincial People's Hospital China 2020-01-30 2020-02-29 ChiCTR2000029782 Phase Not Applicable Not yet recruiting 1 1 Month 27 Tao Song, Yongshi Jia 2020-03-27
Comparative study for integrate Chinese and conventional medicine the the treatment of novel coronavirus pneumonia (COVID-19) in Hu'nan province Coronavirus disease 19 infection, Viral pneumonia integrated Chinese and conventional medicine alone The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine Hunan Provincial Science and Technology Department China 2020-02-21 2020-05-31 ChiCTR2000029960 Phase 0 Clinical Not yet recruiting 1 3 Months 100 CAI Huzhi, CHEN Xinyu 2020-03-27
Clinical Trial for Integrated Chinese and Western Medicine in the Treatment of Children with Novel Coronavirus Pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Integrated Traditional Chinese alone, Western Medicine alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Children's Hospital of Fudan University China 2020-02-14 2020-12-31 ChiCTR2000029814, ChiMCTR2000003013 Phase 0 Clinical Recruiting 1 10 Months 30 Cao Di, Zhai Xiaowen 2020-04-02
A medical records based study for the clinical characteristics of anesthesia novel coronavirus pneumonia (COVID-19) patients during perioperative period and assessment of infection and mental health of Anesthesiology Department Anesthesia, Anxiety disorder, Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Zhangnan Hospital China 2020-01-01 ChiCTR2000029958 Phase Not Applicable Not yet recruiting 1 260 Yingying Chen, Zongze Zhang 2020-03-27
Application of imaging in the prevention and control system of major respiratory infectious diseases Coronavirus disease 19 infection, Lung infection, Viral pneumonia imaging alone The 2nd People's Hospital of Ningbo China 2020-03-01 2020-12-31 ChiCTR2000031150 Phase Not Applicable Recruiting 1 10 Months 150 Jiaying Xu, Jie Lin 2020-03-27
Investigating effect of convalescent plasma on COVID-19 patients outcome: A Clinical Trial Coronavirus disease 19 infection convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Mazandaran University of Medical Sciences, Sari University of Medical Sciences Iran 2020-03-28 2020-09-30 IR.MAZUMS.REC.1399.7330, IRCT20181104041551N1, NCT04327349 Phase 2 Clinical Recruiting 2 6 Months 30 Fatemeh Heidari, Majid Saeedi, Ph.D. 2020-04-01
Traditional Chinese medicine cooperative therapy for patients with novel coronavirus pneumonia (COVID-19): a randomized controlled trial Coronavirus disease 19 infection, Viral pneumonia TCM syndrome differentiation treatment alone, Western medicine conventional chemotherapy regimen alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dongzhimen Hospital China 2020-03-31 2020-12-30 ChiCTR2000029788, ChiMCTR2000003007 Phase Not Applicable Not yet recruiting 1 9 Months 60 Jianwei Shang, Xudong Yu, Yaosheng Zhang 2020-03-27
Chinese Medicine Promotes Rehabilitation Recommendations after 2019 Novel Coronavirus Infection (COVID-19) Coronavirus disease 19 infection, Viral pneumonia guixi regulating lung gong method alone, health guidance alone, moxibustion treatment alone, shenling baizhu powder alone The Affiliated Hospital of Chengdu University of Traditional Chinese Medicine Science & Technology Department of Sichuan Province China 2020-02-18 2020-07-01 ChiCTR2000029956 Phase Not Applicable Not yet recruiting 1 4 Months 120 Tang Jianyuan, Tang Shiyun 2020-03-27
REUSED: A randomized controlled trial for the Efficacy of Ultra Short Wave Electrotherapy in the treatment of Novel Coronavirus Pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Ultra short wave electrotherapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Tongji Hospital, Huazhong University of Science and Technology China 2020-02-17 2020-05-17 ChiCTR2000029972, REUSED Phase Not Applicable Recruiting 1 3 Months 40 Chen Hong, Huang Liangjiang 2020-03-27
The relationship between Vitamin D and novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia, Vitamin D deficiency Male, Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) People’s Hospital of Guangxi Zhuang Autonomous Region China 2020-02-16 2022-02-09 ChiCTR2000031163 Phase Not Applicable No longer recruiting 1 23 Months 80 Kun Ye, Xin Liao 2020-03-27
Auscultatation of Covid-19: Auscultatory characteristics of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Wireless Stemoscope alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shanghai First People's Hospital Shanghai Jiao Tong University China 2020-03-09 2020-06-30 Auscultatation of Covid-19, ChiCTR2000030722 Phase Not Applicable Not yet recruiting 1 3 Months 30 Zhi Zhang 2020-03-27
Study for the physical and mental health status of medical workers under the novel coronavirus pneumonia (COVID-19) epidemic Anxiety disorder, Coronavirus disease 19 infection, Depression Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) The first affiliated hospital of Guangzhou university of Traditional Chinese medicine, Traditional Chinese Medicine Hospital of Hainan Province Affiliated to Guangzhou University of Chinese Medicine, University of Chinese Academy of Sciences Shenzhen Hospital China 2020-03-20 2020-04-30 ChiCTR2000030850 Phase Not Applicable Not yet recruiting 3 1 Month 226 Fengbin Liu, Jinglin Pan 2020-03-27
A medical records based study for Tou-Jie-Qu-Wen Granules in the Treatment of mild and moderate patients with novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Toujiequwen Granules alone, basic treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Guangzhou 8th People's Hospital China 2020-03-13 2020-04-30 ChiCTR2000031089, ChiMCTR2000003144 Phase Not Applicable Not yet recruiting 3 1 Month 300 Huijun Mao, Luping Lin 2020-04-01
Research for Traditional Chinese Medicine Technology Prevention and Control of Novel Coronavirus Pneumonia (COVID-19) in the Community Population Coronavirus disease 19 infection, Viral pneumonia Huoxiangzhengqi oral liquid alone, Jinhao Artemisia Antipyretic granules alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The Affiliated Hospital of Chengdu University of Traditional Chinese Medicine China 2020-01-31 2020-05-01 ChiCTR2000029479, ChiMCTR2000002961 Phase Not Applicable Recruiting 1 3 Months 20000 Tang Jianyuan, Tang Shiyun 2020-03-27
Traditional Chinese Medicine, Psychological Intervention and Investigation of Mental Health for Patients With Novel Coronavirus Pneumonia (COVID-19) in Convalescent Period Coronavirus disease 19 infection, Psychiatric disorder, Viral pneumonia Traditional Chinese Medicine alone, psychological intervention alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hubei Xinhua Hospital, Renmin Hospital of Wuhan University China 2020-02-03 2021-12-31 ChiCTR2000029495 Phase 0 Clinical Not yet recruiting 2 22 Months 90 Min Huang, Zhengliang Li 2020-03-27
Chinese medicine prevention and treatment program for suspected novel coronavirus pneumonia (COVID-19): a perspective, double-blind, placebo, randomized controlled trial Coronavirus disease 19 infection, Viral pneumonia Chinese medicine alone, mechanical ventilation alone, transnasal high-flow oxygen therapy alone, alpha-interferon plus lopinavir + ritonavir HIV protease inhibitor Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Zhejiang Chinese Medical University China 2020-02-04 2020-04-30 ChiCTR2000029517, ChiMCTR2000002963 Phase 0 Clinical Recruiting 1 2 Months 100 Chengping Wen, Zhijun Xie 2020-03-27
A Medical Based Retrospective Real World Study for Assessment of Effectiveness of Comprehensive Traditional Chinese Medicine in the treatment of Novel Coronavirus Pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Chinese medicine alone, Western medicine alone Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Shanghai University of Traditional Chinese Medicine China 2020-02-21 2020-12-31 ChiCTR2000030163, ChiMCTR2000003047 Phase Not Applicable Not yet recruiting 1 10 Months 256 Bin Li, Ruiping Wang 2020-03-30
A cross-sectional study of novel coronavirus pneumonia (COVID-19) patients in ICU Coronavirus disease 19 infection, Viral pneumonia Union Hospital Tongji Medical School Huazhong University Of Science & Technology, Wuhan Jinyintan Hospital China ChiCTR2000030164 Phase Not Applicable Not yet recruiting 2 10 You Shang, Yuan Yu 2020-04-02
Clinical study for ozonated autohemotherapy in the treatment of Novel Coronavirus Pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia conventional treatment alone, ozonated autohemotherapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tianjin University China 2020-02-22 2020-12-31 ChiCTR2000030165 Phase Not Applicable Recruiting 1 10 Months 60 Ni Guangjian, Yu Hongzhi 2020-03-31
Chinese medicine prevention and treatment program for novel coronavirus pneumonia (COVID-19): a perspective, double-blind, placebo, randomized controlled trial Coronavirus disease 19 infection, Viral pneumonia Chinese medicine alone, Western medicine alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Zhejiang Chinese Medical University China 2020-02-04 2020-04-30 ChiCTR2000029518, ChiMCTR2000002964 Phase 0 Clinical Recruiting 1 2 Months 140 Wen Chengping, Xie Zhijun 2020-03-27
Feature of Multiple Organs in Ultrasound Investigation for Clinical Management and Prognostic Evaluation of Novel Coronavirus Pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia invasive ultrasound test alone Renmin Hospital of Wuhan University National Natural Science Foundation of China China 2020-02-17 2020-12-31 ChiCTR2000030017 Phase Not Applicable Recruiting 1 10 Months 200 Bo Hu, Qing Zhou 2020-03-27
Hydroxychloroquine Post-Exposure Prophylaxis for Coronavirus Disease (COVID-19) Coronavirus disease 19 infection hydroxychloroquine sulfate (LIPIN1 disease/rhabdomyolysis), INSERM alone TLR-9 antagonist Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Columbia University US 2020-03-31 2022-03-31 AAAS9676, NCT04318444 Phase 2/Phase 3 Clinical Not yet recruiting 0 24 Months 1600 Elizabeth Oelsner, MD, MPH 2020-03-27
Study for the clinical characteristics and digestive system damage of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Gastrointestinal disease, SARS coronavirus infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Guangzhou 8th People's Hospital China 2020-03-05 2021-03-05 ChiCTR2000030519 Phase 0 Clinical Not yet recruiting 1 12 Months 40 Chuo Li, Yuanjing Zhan 2020-03-27
The COVID-19 Mobile Health Study (CMHS), a large-scale clinical observational registration study using nCapp Coronavirus disease 19 infection, Viral pneumonia nCapp COVID-19 risk diagnostic modelling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shanghai Zhongshan Hospital China 2020-02-28 2020-05-31 ChiCTR2000030019 Phase Not Applicable Not yet recruiting 1 3 Months 600 Chunxue Bai, Dawei Yang 2020-03-27
BCG-CORONA: Reducing health care workers absenteeism in Coronavirus 2019 pandemic nu enhancement of the immune system through vaccination with Bacillus Calmette-Guerin Coronavirus disease 19 infection, SARS coronavirus infection Bacillus Calmette-Guerin vaccine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitair Medisch Centrum Utrecht Netherlands 2020-03-17 2020-12-25 2020-000919-69, 73249, BCG-CORONA, U1111-1249-1107 Phase 4 Clinical Recruiting 10 9 Months 1000 Andreas Voss, MD, PhD, Angele Kerckhoffs, MD, PhD, Anna Roukens, MD, PhD, Bart Rijnders, MD, PhD, Jaap den Oever, MD, PhD, Karin Veerman, MD, Kees van Nieuwkoop, MD, PhD, Marc J. M. Bonten, Thijs ten Doesschate, MD, Wim Boersma, MD, PhD 2020-04-02
COVIDSOT: Multicentric Study of Coronavirus Disease 2019 (COVID-2019) in Solid Organ Transplant Recipients Coronavirus disease 19 infection, Viral pneumonia Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundación Pública Andaluza Para La Gestión De La Investigación En Salud De Sevilla GESITRA-IC, Spanish Network for Research in Infectious Diseases 2020-03-31 2022-04-30 COVIDSOT, COVIDSOT, NCT04319172 Phase Not Applicable Not yet recruiting 0 25 Months 50 Clara Rosso-Fernández, MD-PhD, Elisa Cordero-Matía, MD-PhD 2020-03-27
Medical records based study for the correlation between Chinese medicine certificate and lung image of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chinese Academy of Medical Sciences China 2020-03-09 2021-12-31 ChiCTR2000030597, ChiMCTR2000003096 Phase Not Applicable Not yet recruiting 1 21 Months 150 Miao Qing, Yuan Shasha 2020-03-27
A medical records based analysis for the clinical characteristics of novel coronavirus pneumonia (COVID-19) in immunocompromised patients Coronavirus disease 19 infection, Viral pneumonia medical records based analysis alone Tongji Hospital, Huazhong University of Science and Technology National Natural Science Foundation of China China 2020-01-20 2020-02-29 ChiCTR2000030021 Phase Not Applicable Recruiting 1 1 Month 10 Zhou Min 2020-03-27
A multicenter, open-label observation study for psychological status and intervention efficacy of doctors, nurses, patients and their families in novel coronavirus pneumonia (COVID-19) designated hospitals Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ningbo First Hospital, Zhejiang University China 2020-03-10 2021-03-10 2017C510010, 2018KY671, 2019KY564, ChiCTR2000030697 Phase Not Applicable No longer recruiting 1 12 Months 1500 Zhongze Lou 2020-03-27
A parallel, randomized controlled clinical trial for the efficacy and safety of Pediatric Huatanzhike granules (containing ipecacuanha tincture) in the treatment of mild and moderate novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Pediatric Huatanzhike granules alone, conventional therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) First Affiliated Hospital of Anhui Medical University China 2020-02-22 2020-05-22 ChiCTR2000030022 Phase 4 Clinical Not yet recruiting 6 3 Months 100 Liangdan Sun, Song Fan 2020-03-27
Cancelled due to lack of participants Study for the Impact of Novel Coronavirus Pneumonia (COVID-19) to the Health of the elderly People Coronavirus disease 19 infection, Viral pneumonia Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Third People's Hospital of Chongqing China 2020-02-21 2021-02-28 ChiCTR2000030222 Phase Not Applicable Not yet recruiting 1 12 Months 658 Bin Zhan, Wenjing Sun 2020-03-27
Shedding of SARS-CoV-2 in Human Semen and Evaluation of Reproductive Health of Novel Coronavirus Pneumonia (COVID-19) Male Patients Coronavirus disease 19 infection, SARS coronavirus infection Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Union Hospital Tongji Medical School Huazhong University Of Science & Technology China 2020-03-11 2020-06-30 ChiCTR2000030716 Phase Not Applicable Recruiting 2 3 Months 150 HONGGANG LI 2020-03-27
The treatment status and risk factors related to prognosis of hospitalized patients with novel coronavirus pneumonia (COVID-19) in intensive care unit, Hebei, China: a descriptive study Coronavirus disease 19 infection, Viral pneumonia Hebei Provincial Cancer Hospital Science and Technology Department of Hebei Province of China China 2020-02-01 2020-06-30 ChiCTR2000030226 Phase Not Applicable Recruiting 5 5 Months 40 Yuhong Chen, Zhenjie Hu 2020-03-30
Social Media Effect on Knowledge Dissemination During COVID-19 Virus Outbreak Coronavirus disease 19 infection survey alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Assiut University Egypt 2020-03-11 2020-03-16 ASSIUTU-3-2020, NCT04319315 Phase Not Applicable Recruiting 1 400 Aliae Hussein, MD, Aliae Mohamed-Hussein 2020-03-27
ICU healthcare personnel burnout investigation during the fight against novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Zhangnan Hospital China 2020-02-01 2020-06-01 ChiCTR2000030264 Phase Not Applicable Not yet recruiting 1 4 Months 1000 WANG Jing 2020-03-27
Correlation between imaging characteristics and laboratory tests of new coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Xianning Central Hospital China 2020-02-26 2020-03-31 ChiCTR2000030283 Phase Not Applicable Recruiting 1 1 Month 100 Kaihu Yu, Yi Zheng 2020-03-27
Application of Regulating Intestinal Flora in the Treatment of Severe Novel Coronavirus Pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Regulating intestinal flora alone, conventional treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) The First Affiliated Hospital of Zhengzhou University Science and Technology Department of Henan Province China 2020-02-01 2021-02-01 ChiCTR2000029849 Phase 0 Clinical Recruiting 1 12 Months 60 Huaqi Wang 2020-03-27
Ba-Bao-Dan in the adjuvant therapy of novel coronavirus pneumonia (COVID-19) patients Coronavirus disease 19 infection, Viral pneumonia Ba-Bao-Dan alone, conventional treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shao Yifu Hospital Chinese Government China 2020-02-11 2020-08-11 ChiCTR2000029819 Phase 4 Clinical Recruiting 1 6 Months 80 Xu Hangdi, Ying Kejing 2020-03-26
An observational study on the clinical characteristics, treatment and outcome of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia variety treatments alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ningbo First Hospital China 2020-02-10 2020-03-31 ChiCTR2000029839 Phase 4 Clinical Recruiting 1 1 Month 100 Chao Cao 2020-03-27
Efficacy of Traditional Chinese Medicine in the Treatment of Novel Coronavirus Pneumonia (COVID-19): a Randomized Controlled Trial Coronavirus disease 19 infection, Viral pneumonia general treatment alone, traditional Chinese medicine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) China Academy of Chinese Medical Sciences, Wuhan Jinyintan Hospital National Science and Technology Support Plan of the People's Republic of China China 2020-02-27 2020-12-31 ChiCTR2000030288, ChiMCTR2000003059 Phase Not Applicable Recruiting 1 10 Months 204 Huang Luqi, Ruan Lianguo, Zhao Chen 2020-03-27
A randomized, controlled trial for honeysuckle decoction in the treatment of patients with novel coronavirus (COVID-19) infection Coronavirus disease 19 infection, Viral pneumonia honeysuckle decoction alone Nangjing Second Hospital Affiliated Southeast Medical University, Nanjing University China 2020-02-07 2020-04-30 ChiCTR2000029822 Phase 0 Clinical Recruiting 1 2 Months 110 Likun Zhou, Yongxiang Yi 2020-03-26
Medical records based study for heart-type fatty acid-binding protein on prognosis of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Chongqing Three Gorges Central Hospital China 2020-02-15 ChiCTR2000029829 Phase Not Applicable Terminated 1 40 Wang Hailong 2020-03-27
COVID-19: Effects of Social Isolation From Coronavirus; on Physical Activity, Quality of Life and Stress Coronavirus disease 19 infection, Viral pneumonia beck depression scale alone, physical activity questionnaire alone, short form 12 quality of life scale alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Istanbul University-Cerrahpasa Turkey 2020-03-25 2020-07-20 COVID-19, EAVCIL, NCT04319211, İPEK YELDAN Phase Not Applicable Not yet recruiting 1 3 Months 200 Eren Avcıl, M.Sc,Pt, İpek Yeldan, Prof. 2020-03-26
Clinical observation and research plan of novel coronavirus pneumonia (COVID-19) patients Coronavirus disease 19 infection, Viral pneumonia Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shanghai Public Health Clinical Center China 2020-03-01 2020-05-31 ChiCTR2000030293 Phase Not Applicable Recruiting 1 3 Months 300 Feng Li, Haicheng Tang 2020-04-02
Effects of novel coronavirus pneumonia (COVID-19) on menstruation, TCM body construction and psychological state for female at different ages Anxiety disorder, Coronavirus disease 19 infection, Depression, Menstruation disorder, Viral pneumonia Female, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Chengdu University of Traditional Chinese Medicine Ministry of Science and Technology of the People´s Republic of China China 2020-03-01 2021-02-28 ChiCTR2000030094 Phase Not Applicable Not yet recruiting 1 12 Months 200 Hua Lu, Qi Zhang 2020-03-26
Clinical Trial of Favipiravir Tablets Combine With Chloroquine Phosphate in the Treatment of Novel Coronavirus Pneumonia Coronavirus disease 19 infection, Viral pneumonia favipiravir alone, chloroquine phosphate plus favipiravir RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Beijing Chao-Yang Hospital China 2020-03-05 2020-06-25 2020-K-24-2, NCT04319900 Phase 2/Phase 3 Clinical Recruiting 1 3 Months 150 Lihong Liu, Shumin Wang, Phd. 2020-03-26
CT Scores Predict Mortality in 2019-nCoV Pneumonia Coronavirus disease 19 infection, Viral pneumonia Shanghai First People's Hospital China 2020-01-31 2020-02-18 CT2019-NCOV, NCT04284046 Phase Not Applicable Completed 1 39 Ruilan Wang 2020-03-26
A randomized, open-label, blank-controlled, multicenter trial for Shuang-Huang-Lian oral solution in the treatment of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Lianhua Qingwen alone, Shuanghuanglian alone, routine treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tongji Hospital, Huazhong University of Science and Technology HPGC Renmintongtai Pharmaceutical Corporation China 2020-02-05 2021-02-05 ChiCTR2000029605, ChiMCTR2000002975 Phase 4 Clinical Recruiting 2 12 Months 400 Liu Cailing, Wang Daowen, Zhao Jianping 2020-03-26
COVID-BioB: COVID-19 Patients Characterization, Biobank, Treatment Response and Outcome Predictor Coronavirus disease 19 infection, SARS coronavirus infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universita Vita-Salute San Raffaele Italy 2020-03-19 2022-03-19 COVID-BIOB/OSR, COVID-BioB, NCT04318366 Phase Not Applicable Recruiting 12 24 Months 1000 Adriano Lazzarin, Prof, Alberto Zangrillo, Professor, Andrea Poli, Ing, Angelo AM Manfredi, Prof, Antonella Castagna, Prof, Chiara Bonini, Prof, Chiara Lanzani, Dr, Elisa Vicenzi, Dr, Emanuele Bosi, Prof, Fabio Ciceri, Prof, Giovanni Landoni, Giovanni Landoni, Professor, Giudo Poli, Prof, Lorenzo Dagna, Prof, Lorenzo Piemonti, Prof, Massimo Clementi, Prof, Moreno Tresoldi, Dr, Nicasio Mancini, Prof, Paolo Manunta, Prof, Paolo Scarpellini, Dr, Patrizia Rovere Querini, Prof 2020-04-01
SEROCOV: Sars-CoV2 Seroconversion Among Front Line Medical and Paramedical Staff in Emergency, Intensive Care Units and Infectious Disease Departments During the 2020 Epidemic Coronavirus disease 19 infection, SARS coronavirus infection blood sample alone Healthy volunteers accepted Assistance Publique Hopitaux de Paris France 2020-03-16 2020-10-16 APHP200310, NCT04304690, SEROCOV Phase Not Applicable Recruiting 1 7 Months 1000 David BOUTOLLEAU, MD, Pierre HAUSFATER, MD PHD 2020-03-26
Covid-19 ,remdesivir, Tamiflu Coronavirus disease 19 infection oseltamivir alone, remdesivir alone Exo-alpha sialidase inhibitor, RNA polymerase modulator Hospital Queen Elizabeth Malaysia 2020-03-03 2020-05-01 53302, NMRR-20-347-53302 Phase Not Applicable Status not specified 1 1 Month Dr lem fui fui 2020-03-26
Critically Ill Patients With COVID-19 in Hong Kong: a Multicenter, Observational, Cohort Study Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chinese University of Hong Kong Hong Kong 2020-02-14 2020-02-25 2020.059, NCT04285801 Phase Not Applicable Completed 3 8 Lowell Ling 2020-03-26
A randomized controlled Trial for therapeutic efficacy of Recombinant Human Interferon alpha 1b Eye Drops in the treatment of elderly with novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia recombinant human interferon alpha 1b alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chinese PLA General Hospital China 2020-02-19 2020-05-31 ChiCTR2000029989 Phase 4 Clinical Not yet recruiting 2 3 Months 300 Feng Cao, Yabin Wang 2020-03-26
Traditional Chinese medicine cooperative therapy for patients with Novel coronavirus pneumonia (COVID-19) and its effect on spermatogenesis: a randomized controlled trial Coronavirus disease 19 infection, Viral pneumonia Traditional Chinese medicine alone, Western medicine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dongzhimen Hospital China 2020-02-19 2021-02-18 ChiCTR2000030027 Phase Not Applicable Recruiting 3 12 Months 60 Chun-yan Ji, Jian-wei Shang, Ting-rong Huang, Xu-dong Yu, Yao-sheng Zhang 2020-03-26
A clinical study to study COVID-HIG for the potential treatment of COVID-19 Coronavirus disease 19 infection COVID-HIG alone Emergent BioSolutions Inc 2020-09-30 Phase Not Applicable Planned 0 2020-03-26
A randomized, open and controlled clinical trial for traditional Chinese medicine in the treatment of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Traditional Chinese medicine alone, clear lung prescription alone, compound houttuynia mixture alone, qingfei prescription alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) The First Affiliated Hospital of college of medicine Zhejiang University China 2020-02-15 ChiCTR2000029855 Phase Not Applicable Recruiting 1 180 Wu Guolin 2020-03-27
A randomized controlled trial for the efficacy of Dao-Yin in the prevention and controlling novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Dao Yin alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Shanghai University of Traditional Chinese Medicine Shanghai University of Traditional Chinese Medicine China 2020-02-21 2020-07-31 ChiCTR2000029978, ChiMCTR2000003033 Phase 0 Clinical Not yet recruiting 2 5 Months 186 Fang Min, Zhang Shuaipan 2020-03-31
Study for establishment of correlation between virological dynamics and clinical features in novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Peking University First Hospital China 2020-02-17 2020-08-31 ChiCTR2000030096 Phase Not Applicable Not yet recruiting 1 6 Months 120 Hong Zhao 2020-03-26
A clinical study to study COVID-EIG for the potential treatment of COVID-19 Coronavirus disease 19 infection COVID-EIG alone Emergent BioSolutions Inc 2020-09-30 Phase Not Applicable Planned 0 2020-03-26
CODIV-ACE: ACE Inhibitors, Angiotensin II Type-I Receptor Blockers and Severity of COVID-19 Coronavirus disease 19 infection ACE inhibitors therapy alone, angiotensin receptor-blocker therapy alone, anti-aldosterone agents therapy alone, diuretics therapy alone, Variable regimens including chloroquine , cortisone , lopinavir + ritonavir , remdesivir , sacubitril , tocilizumab , valsartan Angiotensin I receptor antagonist, Angiotensin II receptor antagonist, HIV protease inhibitor, RNA polymerase modulator Neuromed IRCCS Italy 2020-03-23 2020-04-30 CODIV-ACE, DEP-012020, NCT04318418 Phase Not Applicable Not yet recruiting 1 1 Month 5000 Augusto Di Castelnuovo, Augusto Di Castelnuovo, MSc, PhD, Licia Iacoviello, Licia Iacoviello, MD, PhD 2020-03-26
Evaluation of Rapid Diagnostic Kit (IgM/IgG) for Novel Coronavirus Pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia nucleic acid detection method alone Jiangsu Institute of Parasitic Diseases, Jiangsu Provincial People’s Hospital China 2020-02-15 2020-12-31 ChiCTR2000029870 Phase 0 Clinical Recruiting 3 10 Months 600 Cao Jun 2020-03-26
Experimental Trial of rhIFN-alpha Nasal Drops to Prevent 2019-nCOV in Medical Staff Coronavirus disease 19 infection recombinant human interferon alpha-1b alone, recombinant human interferon alpha-1b plus thymalfasin Thymosin receptor agonist Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Shanghai Jiao Tong University China 2020-01-21 2020-06-30 INTERFERON_PROPHYLAXIS, NCT04320238 Phase 3 Clinical Recruiting 1 5 Months 2944 Zhongji Meng 2020-04-01
A randomized, open-label, controlled trial for the safety and efficiency of Kesuting syrup and Keqing capsule in the treatment of mild and moderate novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia conventional therapy alone, Variable regimens including Keqing capsule , Kesuting syrup , conventional therapy Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Guizhou Bailing Group Pharmaceutial Co Ltd, The First Affiliated Hospital of Nanchang University China 2020-02-15 2020-07-18 ChiCTR2000029991, ChiMCTR2000003035 Phase 4 Clinical Recruiting 3 5 Months 24 Tiantian Sun, Wei Zhang 2020-03-26
Transmission dynamic of the novel coronavirus in China Coronavirus disease 19 infection Asian Ancestry Clinical Research Malaysia Malaysia 2020-02-10 2021-02-21 53195, NMRR-20-179-53195, corona01 Phase Not Applicable Status not specified 1 12 Months Law Kian Boon 2020-03-27
CMHS: The COVID-19 Mobile Health Study Coronavirus disease 19 infection nCapp alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chinese Alliance against Lung Cancer Shanghai Respiratory Research Institute China 2020-02-14 2020-05-31 CAALC-008-CMHS, CMHS, NCT04275947 Phase Not Applicable Recruiting 1 3 Months 450 Chunlin Dong, Chunxue Bai, Dawei Yang, Jie Liu, Maosong Ye, Xun Wang, Yong Zhang 2020-03-26
Construction of a bio information platform for novel coronavirus pneumonia (COVID-19) patients follow-up in Anhui Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Anhui Provincial Hospital Chinese Academy of Sciences China 2020-02-01 2022-02-01 ChiCTR2000030331 Phase Not Applicable Recruiting 1 24 Months 498 Weng Jianping, Zheng Xueying 2020-03-31
Study for using multiomics in the diagnosis and treatment of novel coronavirus pneumonia (COVID-19) Bacterial infection, Coronavirus disease 19 infection, Influenza virus infection, Viral pneumonia Healthy volunteers accepted Union Hospital Tongji Medical School Huazhong University Of Science & Technology China 2020-02-18 2020-12-31 ChiCTR2000029982 Phase 0 Clinical Recruiting 1 10 Months 150 Huang Qi, Jin Yang 2020-04-02
A comparative study on the sensitivity of nasopharyngeal and oropharyngeal swabbing for the detection of SARS-CoV-2 by real-time PCR Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia gene sequencing alone, real-time RT-PCR alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Huazhong University of Science and Technology, Tongji Hospital, Tongji Medical College China 2020-02-15 2020-03-31 ChiCTR2000029883 Phase 0 Clinical Not yet recruiting 1 1 Month 200 Xu Shuyun 2020-03-26
COVID-preg: Clinical Characteristics of Coronavirus Disease 2019 (COVID-19) in Pregnancy Coronavirus disease 19 infection Female Universita degli Studi di Napoli Federico II Italy 2020-01-01 2020-05-01 06/20, 145/20, COVID-preg, NCT04319016 Phase Not Applicable Recruiting 1 4 Months 20 Gabriele Saccone 2020-04-02
Rapid DNA Amplification assay for COVID-19 Coronavirus disease 19 infection Rapid Isothermal DNA Amplification assay alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Malaya Malaysia 2020-03-16 2022-03-15 53855, NMRR-20-535-53855 Phase Not Applicable Not yet recruiting 2 24 Months Dr Lau Yee Ling, Dr NUR IZATI BINTI MUSTAPA 2020-03-26
Clinical study of novel NLRP Inflammasome inhibitor (Tranilast) in the treatment of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia conventional therapy alone, tranilast alone Histamine H1 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Anhui Provincial Hospital China 2020-02-15 2020-07-30 ChiCTR2000030002 Phase 4 Clinical Recruiting 1 5 Months 30 Chengchao Ding, Hongliang He 2020-03-26
Evaluate the effectiveness of traditional Chinese medicine in the treatment of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia traditional Chinese medicine alone, western medicine alone Affiliated Hospital of Changchun University of Traditional Chinese Medicine Jilin Provincial Science & Technology Department China 2020-01-31 2020-12-31 ChiCTR2000029896 Phase Not Applicable Recruiting 1 11 Months 100 Shi Li, Wang Tan 2020-03-26
KP COVID-19: KP COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ministry of Health, Malaysia Malaysia 2020-03-23 2020-03-27 54367, KP COVID-19, NMRR-20-559-54367 Phase Not Applicable Not yet recruiting 1 Dr Shubash Shander a/l Ganapathy, Mrs. Komathi Perialathan, PUAN NAZIRAH BINTI ALIAS 2020-03-27
PFACOVID: PFACOVID Coronavirus disease 19 infection, Psychiatric disorder online-based psychological intervention alone Universiti Kebangsaan Malaysia Medical Centre Malaysia 2020-03-02 2021-02-28 54410, NMRR-20-584-54410, PFACOVID Phase Not Applicable Status not specified 1 11 Months Dr Nik Ruzyanei Nik Jaafar, Dr nur iwana binti abdul taib, Dr. Hajar Bt Mohd Salleh Sahimi 2020-03-27
Knowledge and Practice of Infection Control among Ministry of Health staffs during COVID-19 Outbreak Coronavirus disease 19 infection Ministry of Health, Malaysia, National Institutes of Health Malaysia Malaysia 2020-03-23 2020-04-30 NMRR-20-571-54388 Phase Not Applicable Status not specified 1 1 Month Dr Halizah Binti Mat Rifin, Mrs. Komathi Perialathan 2020-03-26
Effect of Novel Coronavirus Pneumonia (COVID-19) on the Mental Health of College Students Coronavirus disease 19 infection, Viral pneumonia Adolescents (13-17 yrs), Young Adults (18-44 yrs) West China Hospital China 2020-02-17 2023-01-31 ChiCTR2000030004 Phase Not Applicable Not yet recruiting 1 35 Months 150000 Tao Li, Xiaojing Li 2020-03-26
SRCOVID-19: SRCOVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ministry of Health, Malaysia Malaysia 2020-01-04 2020-12-31 NMRR-20-574-54389, SRCOVID-19 Phase Not Applicable Not yet recruiting 1 11 Months Dr LOW LEE LAN 2020-04-02
Evaluation the Efficacy and Safety of Hydroxychloroquine Sulfate in Comparison with Phosphate Chloroquine in Severe Patients with Novel Coronavirus Pneumonia (COVID-19): a Randomized, Open-Label, Parallel, Controlled Trial Coronavirus disease 19 infection, Viral pneumonia hydroxychloroquine sulfate alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Peking University Third Hospital China ChiCTR2000029898 Phase 4 Clinical Recruiting 3 100 Shen Ning 2020-03-26
A medical records based study for acute kidney injury in novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia urine analysis alone Tongji Hospital, Huazhong University of Science and Technology National Natural Science Foundation of China China 2020-02-01 2020-05-01 ChiCTR2000030030 Phase Not Applicable Recruiting 1 3 Months 2000 Gang Xu, Shuwang Ge 2020-03-26
Nucleic acid analysis of novel coronavirus pneumonia (COVID-19) in morning sputum samples and pharyngeal swabs-a prospectively diagnostic test Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tongji Hospital, Huazhong University of Science and Technology China 2020-02-21 2020-04-21 ChiCTR2000030005 Phase Not Applicable Not yet recruiting 1 2 Months Cheng Yu, Jingzhi Ma 2020-03-26
Study on ultrasonographic manifestations of new type of novel coronavirus pneumonia (covid-19) in non-critical stage of pulmonary lesions Coronavirus disease 19 infection, Viral pneumonia ultrasonography alone Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Xi'an Chest Hospital China 2020-02-10 2020-03-28 ChiCTR2000030032 Phase Not Applicable Recruiting 1 1 Month 20 Huang Yi 2020-03-26
Assessment of Serological Response and Potential Risk Factors for COVID-19 Infection Among Healthcare Workers Coronavirus disease 19 infection Clinical Research Malaysia Malaysia 2020-01-01 2020-03-31 NMRR-20-575-54382 Phase Not Applicable Status not specified 1 3 Months Dr Lee Yee Leng 2020-03-26
Study for the TCM syndrome characteristics of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Guangdong Provincial Hospital of Chinese Medicine, Hubei Hospital of Integrated Traditional Chinese and Western Medicine Zhongshan Branch, Tianjin University of Traditional Chinese Medicine China 2020-02-02 2020-12-01 ChiCTR2000029430, ChiMCTR2000002947 Phase Not Applicable Not yet recruiting 1 10 Months 600 ZHANG Boli, ZHANG Zhongde, Zhang Juhana 2020-04-01
A real world study for Compound Houttuyniae Mixture for prevention of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Compound Houttuynia Mixture alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Lishui People's Hospital, Wenzhou Central Hospital, Yancheng Hospital of TCM affiliated to Nanjing University of Chinese Medicine Zhejiang Conba Traditional Medicine Co.,Ltd China 2020-02-29 2020-06-30 ChiCTR2000030168, ChiMCTR2000003045 Phase Not Applicable Not yet recruiting 3 4 Months 2000 Dawei Wang, Ruifan Shi 2020-03-31
Effect evaluation and prognosis of Chinese medicine based on Novel Coronavirus Pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Traditional Chinese Medicine alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The first affiliated Hospital Of Anhui University Of Traditional Chinese Medicine Department of Science and Technology of Anhui Province China 2020-02-10 2021-02-10 ChiCTR2000029747 Phase 0 Clinical Recruiting 3 12 Months 200 Mei Dong, Nianzhi Zhang 2020-03-27
COVID: Closed-Loop Oxygen to Verify That Healthcare Workers Interventions Decrease During Pneumonia Coronavirus disease 19 infection, Viral pneumonia FreeO2 alone, oxygen alone, usual care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universite Laval 2020-04-06 2021-10-31 2020-3445, 21909, COVID, NCT04320056 Phase 2 Clinical Not yet recruiting 0 18 Months 216 François Lellouche, Pierre-Alexandre Bouchard 2020-03-30
Clinical study for the remedy of M1 macrophages target in the treatment of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia M1 suppression therapy alone, methylprednisolone alone, severe intesive treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Affiliated Zhongshan Hospital of Dalian University China 2020-01-29 2020-12-31 ChiCTR2000029431 Phase 0 Clinical Recruiting 2 11 Months 45 Dewei Zhao, Zhijie Ma 2020-03-31
Evaluation the Efficacy and Safety of Hydroxychloroquine Sulfate in Comparison with Phosphate Chloroquine in Mild and Commen Patients with Novel Coronavirus Pneumonia (COVID-19): a Randomized, Open-label, Parallel, Controlled Trial Coronavirus disease 19 infection, Viral pneumonia hydroxychloroquine sulfate alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Peking University Third Hospital China 2020-02-17 2020-04-30 ChiCTR2000029899 Phase 4 Clinical Recruiting 3 2 Months 100 Shen Ning 2020-03-26
A randomized, open-label, blank-controlled trial for Lian-Hua Qing-Wen Capsule/Granule in the treatment of suspected novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia lianhua qingwen (oral/capsule, influenza), Yiling Pharmaceutical alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hebei Yiling Hospital, Renmin Hospital of Wuhan University Shijiazhuang Yiling Pharmaceutical Co Ltd China 2020-02-01 2020-12-01 ChiCTR2000029433, ChiMCTR2000002949 Phase 4 Clinical Not yet recruiting 7 10 Months 240 Duan Zhongping, Han Shuolong, Jia Zhenhua, Li Lanjuan, Li Xingwang, Liu Qingquan, Song Yuanlin, Zhang Boli, Zhong Nanshan 2020-04-02
Convalescent plasma for the treatment of severe and critical novel coronavirus pneumonia (COVID-19): a prospective, randomized, controlled trial Coronavirus disease 19 infection, Viral pneumonia antibacterial treatment alone, antiviral treatment alone, convalescent plasma alone, symptomatic treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) China-Japan Friendship Hospital, Institute of Blood Transfusion, Chinese Academy of Medical Sciences, Union Hospital Tongji Medical School Huazhong University Of Science & Technology China 2020-02-14 2021-02-05 ChiCTR2000029757 Phase 0 Clinical Recruiting 12 11 Months 200 Cao Bin, Liu Zhong 2020-03-27
COVID-19/HSB1: COVID-19/HSB1 Coronavirus disease 19 infection Hospital Sungai Buloh Malaysia 2020-04-01 2021-03-31 54339, COVID-19/HSB1, NMRR-20-580-54339 Phase Not Applicable Status not specified 1 12 Months Dr Mohan Dass Pathmanathan 2020-03-30
A randomized controlled trial for the efficacy of ozonated autohemotherapy in the treatment of Novel Coronavirus Pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia ozonated autohemotherapy alone Union Hospital Tongji Medical School Huazhong University Of Science & Technology China 2020-02-19 2020-05-19 2018YFC2001802, ChiCTR2000030006 Phase Not Applicable Recruiting 1 3 Months 30 Chen Xiangdong, Han Linlin 2020-03-26
Research for Risks Associated with Novel Coronavirus Pneumonia (COVID-19) in the Hospital Workers and Nosocomial Prevention and Control Strategy Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Renmin Hospital of Wuhan University China 2020-02-17 2020-02-29 ChiCTR2000029900 Phase Not Applicable Not yet recruiting 1 200 Bimuchibu, Yu Jia 2020-03-26
A medical records based study of novel coronavirus pneumonia (COVID-19) and influenza virus co-infection Coronavirus disease 19 infection, Influenza virus infection, SARS coronavirus infection, Viral pneumonia Hubei Clinical Research Center, Zhangnan Hospital China 2020-02-10 2020-03-15 ChiCTR2000029905 Phase Not Applicable Recruiting 1 1 Month 271 Zhao Yan, Zhou Xianlong 2020-03-26