Last updated: May 07, 2020 - 02:00 BST

Title Indication Intervention Actions PatientSelection Sponsor Collaborator Country StartDate EndDate Identifiers Phase Recruitment Status Sites Trial Duration Enrollment Count Contacts LastChanged
TRIIM-X: Thymus Regeneration, Immunorestoration, and Insulin Mitigation Extension Trial Aging, Cancer, Cardiovascular disease, Coronavirus disease 19 infection, Dementia, Diabetes mellitus, Infectious disease Variable regimens including DHEA , metformin hydrochloride , somatropin AMP activated protein kinase stimulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Intervene Immune Inc US 2020-10-31 2022-10-31 NCT04375657, TRIIM-X, TRIIM-X Phase 2 Clinical Recruiting 0 24 Months 85 Gregory M Fahy, PhD, Robert Brooke 2020-05-06
Community Pharmacists Behavior During Covid-19 Coronavirus disease 19 infection face to face interview alone, online google form survey alone, semi-structured telephone interview alone Damanhour University Egypt 2020-05-02 2021-04-30 NCT04374513, PHARMACISTS AND COVID-19 Phase Not Applicable Recruiting 0 11 Months 50 Amira Kassem, PhD, Amira Kassem, phD, Asser Ghoneim, phD, Noha El Bassiouny, PhD 2020-05-06
The effect of addition of selenium to treatment regimen of hospitalized patients with corona on the outcome of disease compared with control group Coronavirus disease 19 infection antibiotic therapy alone, antiretroviral therapy alone, selenium alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sabzevar University of Medical Sciences Iran 2020-05-20 IR.MEDSAB.REC.1399.017, IRCT20160706028815N5 Phase 2 Clinical Not yet recruiting 0 40 Afsaneh Kaffash, Fereshteh Ghorat 2020-05-06
I-SPY COVID: A clinical trial to rapidly identify therapies to treat acute respiratory distress syndrome (ARDS) in critically ill COVID-19 patients Coronavirus disease 19 infection, Respiratory distress syndrome standard-of-care alone QuantumLeap Healthcare, University of California San Francisco US I-SPY COVID Phase Not Applicable Status not specified 0 Laura Esserman 2020-05-06
A first in human clinical trial of DPX-COVID-19 for the potential prevention of COVID-19 Coronavirus disease 19 infection DPX-COVID-19 alone McGill University Health Center Fonds de solidarité FTQ 2020-07-31 Phase Not Applicable Planned 0 2020-05-06
Level and Predictors of Trauma-symptoms Among Health Workers and Public Service Providers During the COVID-19 Outbreak Anxiety disorder, Coronavirus disease 19 infection, Depression, Injury, Post traumatic stress disorder Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Oslo Modum Bad Norway 2020-03-31 2020-04-07 NCT04374097, REK125510(2) Phase Not Applicable Completed 1 1778 Asle Hoffart, PhD, Omid Ebrahimi, Sverre Urnes Johnson, PhD 2020-05-06
PROVID: PROne Positioning in coVID-19 Oxygeno-dependent Patients in Spontaneous Ventilation (PROVID Study) Coronavirus disease 19 infection Prone positioning alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-04-30 2020-07-31 APHP200504, NCT04366856, PROVID Phase Not Applicable Not yet recruiting 1 3 Months 500 Anatole HARROIS, Anatole HARROIS, MD, Anatole HARROIS, MD, PhD 2020-05-06
Pulmonary Rehabilitation in Post-Acute Period of COVID-19 Infection Anxiety disorder, Coronavirus disease 19 infection, Depression, Dyspnea, Fatigue, Myalgia Pulmonary Rehabilitation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Istanbul Bilgi University Turkey 2020-03-11 2020-04-26 NCT04365738, PR COVID-19 Phase Not Applicable Completed 1 1 Month 270 Tomri̇s Duymaz 2020-05-06
Recombinant Bacterial ACE2 Receptors -Like Enzyme of B38-CAP Could be Promising COVID-19 Infection- and Lung Injury Preventing Drug Better Than Recombinant Human ACE2 (Bacterial ACE2) Coronavirus disease 19 infection, Lung injury recombinant bacterial ACE2 receptors -like enzyme of B38-CAP (rbACE2) alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kafrelsheikh University Egypt 2020-08-31 2020-10-31 NCT04375046, PROPOSED BY MAHMOUD KAZAZZAZ Phase 1 Clinical Not yet recruiting 0 2 Months 24 M.Sc. Mahmoud Elkazzaz, M.Sc.Biochemistry, M.Sc.Mahmoud Elkazzaz, M.Sc.Biochemistry, Mahmoud Ramadan mohamed Elkazzaz 2020-05-06
An expanded access for compassionate use program to assess stem cells in the treatment of patients with COVID-19 infection Coronavirus disease 19 infection stem cells alone GIOSTAR US Phase Not Applicable Not yet recruiting 0 Dr. Prabhat Soni 2020-05-06
Prehospital Intubation of COVID-19 Patient With Personal Protective Equipment Cardiac arrest, Coronavirus disease 19 infection Vie Scope laryngoscopy alone, endotracheal intubation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Lazarski University Medical University of Bialystok, Poznan University of Medical Sciences, Wroclaw Medical University Poland 2020-03-20 2020-05-20 INT_EMS_PPE_1, NCT04365608 Phase Not Applicable Recruiting 2 2 Months 90 Lukasz Szarpak, PhD, Marek Dabrowski, PhD 2020-05-06
MYOCOVID: Hospital Registry of Acute Myocarditis: Evolution of the Proportion of Positive SARS-COV-2 (COVID-19) Cases Coronavirus disease 19 infection, Myocarditis CT scan alone, bacteriological test alone, immunological test alone, myocardial MRI alone, myocardial biopsy alone, parasitic tests alone, polymerase chain reaction alone, routine care alone, transthoracic echocardiography alone, viral test alone Centre Hospitalier Universitaire de Toulouse France 2020-04-15 2021-10-15 MYOCOVID, NCT04375748, RC31/20/0139 Phase Not Applicable Recruiting 1 18 Months 400 Audrey TOMASIK, Clément Delmas 2020-05-06
RECOVER: Trial to Promote Recovery From COVID-19 With Ivermectin or Endocrine Therapy Coronavirus disease 19 infection bicalutamide alone, standard of care alone Androgen receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sidney Kimmel Comprehensive Cancer Center US 2020-06-30 2021-06-30 COV2003, IRB00249425, NCT04374279, RECOVER Phase 2 Clinical Not yet recruiting 0 12 Months 60 Aliya Lalji, MD, Catherine H Marshall, MD/MPH, Jeffrey Rothstein, MD/PhD, Lindsey Hayes, MD/PhD, Samuel Denmeade, MD, Shawn Kwatra, MD, Vasan Yegnasubramanian, MD/PhD 2020-05-06
Early warning model and new biomarker of severe novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Anhui Provincial Hospital China 2020-01-10 2020-05-30 ChiCTR2000032460 Phase 0 Clinical No longer recruiting 1 4 Months 350 Meiqiao Chen, Wenting Li 2020-05-06
Effects of Mobile App in House Staff Health and Well-being During COVID-19 Pandemic Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Sleep disorder Calm Meditation App alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Arizona US 2020-05-01 2020-10-01 NCT04374786, TO BE DETERMINED Phase Not Applicable Not yet recruiting 0 5 Months 328 Kelley Saunders, Kelley T Saunders, MD, Mike Foley, MD, Rachael Smith, DO 2020-05-06
COR-CARDIO: Drug Safety and the Occurrence of Complications During Hospitalization in Patients With COVID-19 Cardiovascular disease, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instytut Kardiologii Im Prymasa Tysiaclecia Poland 2020-04-24 2021-08-24 1860/2020, COR-CARDIO, NCT04374110 Phase Not Applicable Not yet recruiting 0 16 Months 1000 Aleksander Prejbisz, MD, PhD, Andrzej Januszewicz, MD, PhD, Piotr Dobrowolski, MD, PhD, Rafal Dabrowski, MD, PhD, Tomasz Hryniewiecki, MD, PhD 2020-05-06
Treatment of Angiotensin Peptide (1-7) for COVID-19 Coronavirus disease 19 infection angiotensin peptide (1-7) derived plasma alone, routine treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Istanbul Bakirkoy Maternity and Children Diseases Hospital Turkey 2020-04-25 2020-09-30 KSSEAH--0059, NCT04375124 Phase 2 Clinical Not yet recruiting 0 5 Months 20 Hasan Onal, Seda Y Semerci 2020-05-06
Anosmia Rehabilitation in Patients Post Coronavirus Disease (COVID 19) Coronavirus disease 19 infection, Dysomia, Viral respiratory tract infection Nasal irrigation alone, NeilMed Sinus Rinse alone, NeilMed Sinus Rinse bottle alone, Olfactory retraining alone, budesonide plus budesonide (inhaled formulations), AstraZeneca Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Lawson Health Research Institute Canada 2020-06-30 2021-12-31 ANOSMIA_COVID 19, NCT04374474 Phase 4 Clinical Not yet recruiting 2 18 Months 75 Brian Rotenberg, MD, Janet Knechtel, Khrystyna Ioanidi, MD, Leigh J Sowerby, Leigh J Sowerby, MD, Leigh Sowerby, MD, FRCSC, Sherry Paiva 2020-05-06
COVID-19 Serology Screening and Strict Protocol in the Endoscopy Unit Coronavirus disease 19 infection endoscopic examination alone, nucleic acid PCR testing alone, serological screening alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) INSTITUTO ECUATORIANO DE ENFERMEDADES DIGESTIVAS GASTROCLINICA S.A Ecuador 2020-04-20 2020-06-01 IECED-04-15-COVID, NCT04374123 Phase Not Applicable Recruiting 0 1 Month 80 Carlos A Robles-Medranda, MD, Roberto A Oleas, MD 2020-05-06
HEROS: COVID-19: Human Epidemiology and Response to SARS-CoV-2 Asthma, Coronavirus disease 19 infection Healthy volunteers accepted, Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) National Institute of Allergy and Infectious Diseases Rho Inc US 2020-05-01 2020-12-31 DAIT-COVID-19-001, HEROS, NCT04375761 Phase Not Applicable Recruiting 0 8 Months 8000 Alexandra Connolly, Amanda Cyrus, Andrew Liu, MD, Asel Baatyrbek, Christine C. Johnson, PhD, Christine M. Seroogy, MD, Daniel J. Jackson, MD, Dolores Santoyo, Edward Zoratti, MD, Elizabeth Tesson, George T. O'Connor, MD, MS, Gurjit K. Khurana Hershey, MD, PhD, Jen Smith, Kyle Koshalek, Kyra Jones, Leonard B. Bacharier, MD, Nicole Gonzalez, Pamela Groh, Pascuala Pinedo-Estrada, Rebecca Gruchalla, MD, Sherae Hereford, Stephen Teach, MD, Tiffany Ogundipe, Tina V. Hartert, MD, MPH, Zachary Flege 2020-05-06
COLVID-19: Colchicine in COVID-19: a Pilot Study Coronavirus disease 19 infection, Viral pneumonia colchicine alone, current care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universita Degli Studi Di Perugia Italy 2020-04-18 2020-10-31 2020-001475-33, COLVID-19, NCT04375202 Phase 2 Clinical Recruiting 2 6 Months 308 Carlo Scirè, Claudia Diana, Prof Roberto Gerli 2020-05-06
A Phase II, Open-Label, Randomized, Controlled Trial to Assess the Safety and Efficacy of Convalescent Plasma to Limit COVID-19 Associated Complications Coronavirus disease 19 infection, Respiratory distress syndrome, Sepsis convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Max Healthcare Institute Ltd, India India 2020-05-09 2021-05-09 MHC-COVID-19-CP, NCT04374487 Phase 2 Clinical Not yet recruiting 0 12 Months 100 Deven Juneja, DNB, Rahul Naithani, MD, DM, Rajesh Saxena, MBA, Sandeep Budhiraja, MRCP,FACP, Sangeeta Pathak, MBBS,Diploma 2020-05-06
Stem cell therapy in COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia adipose and placenta-derived mesenchymal stem cell alone, common treatment alone Kermanshah University of Medical Sciences Iran 2020-05-09 IR.KUMS.REC.1399.065, IRCT20200418047121N2 Phase 1/Phase 2 Clinical Not yet recruiting 0 6 Farid Najafi, Kamran Mansouri 2020-05-06
Monocytes and NK Cells Activity in Covid-19 Patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Università degli Studi dell'Insubria Italy 2020-04-27 2020-10-31 67/2020, NCT04375176 Phase Not Applicable Recruiting 1 6 Months 150 Andrea Vigezzi, MD, Andreina Baj, MD, Angelo Genoni, Dr, Annarosaria De Vito, PhD, Caterina Franchi, MD, Daniela Dalla Gasperina, Professor, Denisa Baci, PhD, Domenico Iovino, M.D., Domenico Iovino, MD, Elisa Monti, MD, Federica Masci, MD, Francesco Acquati, Professor, Giulio Carcano, Professor, Giuseppe Ietto, M.D., Giuseppe Ietto, MD, Lorenzo Mortara, Professor, Matteo Gallazzi, PhD, Valentina Iori, MD, Walter Ageno, Professor 2020-05-06
A Study of N-acetylcysteine in Patients With COVID-19 Infection Coronavirus disease 19 infection N-acetylcysteine alone, supportive care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Memorial Sloan-Kettering Cancer Center US 2020-05-01 2021-05-31 20-168, NCT04374461 Phase 2 Clinical Recruiting 0 13 Months 86 Jedd Wolchok, MD, PhD, Santosha Vardhana, MD, PhD 2020-05-06
Inhalable Sodium Bicarbonate: a Possible Adjuvant Treatment of Patients With Novel COVID-19 Coronavirus disease 19 infection, Viral pneumonia nebulizer alone, oseltamivir plus sodium bicarbonate Exo-alpha sialidase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mansoura University Egypt 2020-04-01 2020-06-01 NCT04374591, SODIUM BICARBONATE COVID-19 Phase 0 Clinical No longer recruiting 1 2 Months 20 Mohammed K Elbadrawy, PhD 2020-05-06
COVHECBEHO: COVID-19 Among Healthcare Workers in Belgian Hospitals Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sciensano Institute of Tropical Medicine Antwerp Belgium 2020-04-22 2020-09-27 COVHECBEHO, NCT04373889, SCIENSANO Phase Not Applicable Recruiting 3 5 Months 800 Els Duysburgh, MD, MPH, PhD, Laure Mortgat, MD, MPH, Wesley Van Dessel 2020-05-06
Quality of Life and Physical Performance After Novel Coronavirus Infection (COVID-19) Coronavirus disease 19 infection education sessions alone, physical exercise alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kantonsspital Winterthur KSW Switzerland 2020-03-15 2021-08-31 2020_00899 / COV19_2020, NCT04375709 Phase Not Applicable Recruiting 1 17 Months 60 Cornel Sieber, Prof. MD, David Gisi, Giuseppe Mungo, MSc, Ines Unger, MSc Cand., Karrer Urs, PD MD, Markus Hofer, MD, Martina Betschart, PhD, Natalie Ott, MSc Cand., Spencer Rezek, MSc Cand., Swantje Beyer, MD 2020-05-06
LIFESAVER: Early transfusion of Convalescent Plasma in Elderly COVID-19 Patients to Prevent Disease Progression Coronavirus disease 19 infection COVID-19 Convalescent Plasma alone, standard therapy alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) Policlinico Universitario Agostino Gemelli Italy 2020-05-15 2021-06-30 3205, LIFESAVER, NCT04374526 Phase 2/Phase 3 Clinical Not yet recruiting 3 13 Months 182 Andrea Antinori, Prof., Antonella Cingolani, Jacopo Vecchiet, Prof., Luciana Teofili, Luciana Teofili, Prof., Maurizio Sanguinetti, Raffaele Landolfi, Prof. 2020-05-06
COVID19-HOPE: Hydroxychloroquine in Combination With Azithromycin or Sirolimus for Treating COVID-19 Patients Coronavirus disease 19 infection Variable regimens including azithromycin , hydroxychloroquine , sirolimus mTOR inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) King Hussein Cancer Center Jordan 2020-05-01 2020-09-01 20 KHCC 74, COVID19-HOPE, NCT04374903 Phase 2 Clinical Not yet recruiting 1 4 Months 58 Abdelghani Tbakhi, PhD, Amal Al Omari, PhD, Anwar Alnassan, MD, Dalia Al Rimawi, MDS, Feras Hawari, MD, Hikmat Abdel-Razeq, MD, Iyad Ammouri, MD, Iyad Sultan, MD, Mayada Abu Shanap, MD, Mohammed Abufaraj, Prof., Nedal Al-Rawashdeh, MPH, Osama Abu Ata, MD, Rana Damsees, MPH, Rula Najjar, Pharm. D 2020-05-06
Risk of Venous Thromboembolism in Critically Ill Patients With Severe COVID-19 Coronavirus disease 19 infection, Deep vein thrombosis, Lung embolism, Viral pneumonia blood test alone, computed tomography angiography alone, duplex ultrasound alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Vall D'Hebron Spain 2020-04-01 2020-05-01 NCT04374617, PR(AG)213/2020 Phase Not Applicable Completed 3 1 Month 230 Sergi Bellmunt, MD,PhD 2020-05-06
Study of Oral Ibrutinib Capsules to Assess Respiratory Failure in Adult Participants With CoronaVirus Induced Disease 2019 (COVID-19) and Pulmonary Distress Coronavirus disease 19 infection, Respiratory failure ibrutinib alone, standard care alone Btk tyrosine kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) AbbVie Inc Janssen Research & Development LLC US 2020-05-06 2020-08-27 M20-310, NCT04375397 Phase 2 Clinical Not yet recruiting 0 3 Months 46 ABBVIE CALL CENTER, AbbVie Inc. 2020-05-06
ACT: Asymptomatic COVID-19 Trial Coronavirus disease 19 infection Hydroxychloroquine sulfate alone, Hydroxychloroquine sulfate plus azithromycin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rutgers University US 2020-05-05 2021-04-30 ACT, NCT04374552, PRO2020000872 Phase 2 Clinical Not yet recruiting 0 11 Months 140 Helaine Noveck, MPH, Jeffrey L Carson, MD 2020-05-06
Convalescent Plasma for Treatment of COVID-19 Patients With Pneumonia Coronavirus disease 19 infection, Viral pneumonia High-Titer Anti-SARS-CoV-2 (COVID 19) Convalescent Plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Virginia US 2020-05-05 2021-04-05 200114, NCT04374565 Phase 2 Clinical Not yet recruiting 0 11 Months 29 Alex Kadl, MD, Amy Mathers, MD, Archana Thakur, PhD, Chelsea Sheppard, MD, James Gorham, MD, Jeffrey M. Sturek, MD, PhD, Jeffrey Sturek, Karen Ballen, MD, Kristen M Petros De Guex, MA, Lawrence G. Lum, MD, DSc, Melinda Poulter, PhD, Patrick Jackson, MD, Qin Liu, MD, PhD, Scott Heysell, MD, Taison Bell, MD, Tania Thomas, MD, MPH, William B Harrington, MPH 2020-05-06
COVIDANS Study: Testing for Dysautonomia in Patients Hospitalized for SARS-CoV-2 Infection (COVID-19) Autonomic nervous system disease, Coronavirus disease 19 infection ECG-Holter alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire de Saint Etienne France 2020-05-31 2020-10-31 2020-A01082-37, 20CH095, COVIDANS Study, NCT04374045 Phase Not Applicable Not yet recruiting 1 5 Months 25 Béatrice DEYGAS, CRA, David CHARIER, MD 2020-05-06
SARSCoV2 (COVID-19) Convalescent Plasma (CP) Expanded Access Protocol (EAP) Coronavirus disease 19 infection betacoronavirus (SARSCoV2) convalescent plasma (CP) alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) AdventHealth US 1596191, NCT04374370 Phase Not Applicable Recruiting 0 Chris Ensor, PharmD, Eduardo Oliveira, MD 2020-05-06
Incidence and risk factors for acute kidney injury in COVID-19 Coronavirus disease 19 infection, Renal injury Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Klinikum der Albert-Ludwigs Universitaet Freiburg Germany 2020-03-01 2020-04-30 276/20, DRKS00021658 Phase Not Applicable Completed 1 2 Months 100 Johanna Schneider 2020-05-06
Efficacy and Safety of Early COVID-19 Convalescent Plasma in Patients Admitted for COVID-19 Infection Coronavirus disease 19 infection, Respiratory failure Anti-SARS-COV-2 convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Pontificia Universidad Catolica De Chile Arturo Lopez Perez Foundation Chile 2020-05-04 2021-12-31 200415015, NCT04375098 Phase 2 Clinical Recruiting 0 19 Months 30 Maria Elvira Balcells, MD 2020-05-06
CovOM: Investigating the microorganisms found in the mouths of SARS-Cov-2 positive patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Ferrara Italy 2020-04-09 2020-10-01 COVOM, CovOM, ISRCTN87832712 Phase Not Applicable Not yet recruiting 3 5 Months 20 Prof Caselli 2020-05-06
Homoeopathy as adjuvant in management of coronavirus infection Coronavirus disease 19 infection homoeopathic medicines alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bajaj Auto Ltd India 2020-05-08 CTRI/2020/04/024925 Phase 2 Clinical Not yet recruiting 1 100 Dr Abhay S Talwalkar, Dr Anil Khurana, Dr Ayushi Shrikhande, Dr Govindarajan Sankaran 2020-05-06
A medical records based retrospective study: leukopenia is more common in asymptomatic patients less than 18 years old with novel coronavirus pneumonia (COVID-19) in convalescence Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Guizhou Provincial Staff Hospital, The Science and Technology Department of Guizhou Province China 2020-04-01 ChiCTR2000032458 Phase Not Applicable No longer recruiting 1 25 Wei Zhang 2020-05-06
A Clinical Trial to Ascertain the Effect of Homoeopathic Medicines in Prevention of Outbreak of Symptoms in Asymptomatic Coronavirus and Suspected Coronavirus Patients Coronavirus disease 19 infection homoeopathic medicine alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Naiminath Homoeopathic Medical College, Hospital and Research Centre India 2020-05-10 C-2020/05, CTRI/2020/04/024926 Phase 3 Clinical Not yet recruiting 1 100 Dr Ritu Gupta 2020-05-06
Diagnostic value of chest CT in outpatient for novel coronavirus pneumonia (COVID-19) compared to RT-PCR Coronavirus disease 19 infection, Viral pneumonia RT-PCR alone, chest-CT alone The Fifth People's Hospital of Ganzhou China 2020-01-01 2020-02-29 ChiCTR2000032574 Phase Not Applicable No longer recruiting 1 2 Months 248 Zhang Weiwei 2020-05-06
A randomized, double-blind, controlled trial for Bu-Fei-Huo-Xue Capsule in the treatment of novel coronavirus pneumonia (COVID-19) convalescence patient with ''Fei-Pi-Qi-Xu zhen'' Coronavirus disease 19 infection, Viral pneumonia Bufei Huoxue Capsule alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) State Key Laboratory Of Respiratory Diseases, The Fifth Affiliated Hospital of Guangzhou Medical University China 2020-05-02 2021-05-01 ChiCTR2000032573 Phase 0 Clinical Not yet recruiting 5 12 Months 120 Jian Wang, Nanshan Zhong 2020-05-06
Placental Mesenchymal Stem Cell Therapy for Acute Respiratory Distress Syndrome in Coronavirus Infection: A Phase I/II Clinical Trial Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia placental mesenchymal stem cell therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) National Institute for Medical Research Developement, Oghaf Organization and charity, Opal Parsian Company Iran 2020-03-20 IR.TUMS.VCR.REC.1399.009, IRCT20200413047063N1 Phase 1/Phase 2 Clinical Recruiting 2 20 Masoud Soleimani, Mohamad Azimi, Mohammad Alian Nejad, Mohammad Mokhber, Mohammad Reza Hashemian, Mohammad Vasei, Reza Malekzadeh, Sayed Mahdi Khamooshi 2020-05-06
Ozone Autohemotherapy in COVID-19 Coronavirus disease 19 infection conventional therapy alone, major autohemotherapy alone, ozone alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Tabriz University of Medical Sciences Iran 2020-04-25 IR.TBZMED.REC.1399.022, IRCT20190618043923N4 Phase 2/Phase 3 Clinical Recruiting 1 20 Dawood Aghamohammadi, Mohammad Samiei 2020-05-06
PIONEER: A Randomized, Controlled Trial of Early Intervention in COVID-19: Favipiravir Versus Hydroxycholorquine and Azithromycin and Zinc versus Standard Care Coronavirus disease 19 infection, Influenza virus infection favipiravir alone, standard clinical care alone, Variable regimens including Plaquenil , azithromycin , zinc sulfate RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chelsea & Westminster NHS Trust FUJIFILM Toyama Chemical Co Ltd, Imperial College London, Neat Id Foundation, Universitaire Ziekenhuizen Leuven UK 2020-05-01 2021-03-31 2020-001449-38, CW002, NCT04373733, PIONEER Phase 3 Clinical Not yet recruiting 2 11 Months 450 Bobby Mann, Pallav Shah, Research Delivery Operations Manager 2020-05-06
A Clinical Trial to study the effectiveness of Homoeopathy as an additional mode of treatment in combating Corona Virus infection Coronavirus disease 19 infection Homoeopathy (Arsenic Album, Bryonia Alba, Gelsemium, Antimonium Tartaricum, Crotalus Horridus) alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Central Council for Research in Homeopathy, Naiminath Homoeopathic Medical College, Hospital and Research Centre India 2020-05-05 C-2020/01, CTRI/2020/04/024905 Phase 3 Clinical Not yet recruiting 1 100 Dr Shaurabh Kumar 2020-05-05
PROTEGO: Prospective, Observational, Cohort Trial Evaluating Correlation of Clinical Findings, Symptoms And Disease Development Of German In- Or Outpatients Infected With SARS-CoV-2 - A CHIR-Net Student-Initiated German Medical Audit trial COVID-19 study (CHIR-Net SIGMA study group) Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Heidelberg Germany 2020-05-07 DRKS00021226, PROTEGO, S-215/2020, U1111-1250-1571 Phase Not Applicable Not yet recruiting 2 500 André Mihaljevic 2020-05-06
The effect of Intravenous immunoglobulin on COVID-19 infection Coronavirus disease 19 infection Intratect alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gonabad University of Medical Sciences Iran 2020-03-10 IR.GMU.REC.1399.009, IRCT20200418047116N1 Phase 2 Clinical Recruiting 1 20 Dr. Shahla Khosravan, Najme Davoodian, Negar Shafaei Bajestani 2020-05-06
ATTACC: Antithrombotic Therapy to Ameliorate Complications of COVID-19 Coronavirus disease 19 infection dalteparin sodium alone, enoxaparin sodium alone, tinzaparin sodium alone, unfractionated heparin alone Antithrombin III, Factor IIa antagonist, Factor Xa antagonist, Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Manitoba Hamilton Health Sciences Corp, Hopital Montfort, The University Health Network Canada 2020-05-31 2021-01-31 ATTACC, ATTACC, NCT04372589, OZM-113 Phase 2 Clinical Not yet recruiting 4 8 Months 3000 Jean-Philippe Galanaud, MD, Marc Carrier, MD, Patrick Lawler, MD, Peter Gross, MD, Ryan Zarychanski, MD 2020-05-06
C-reactive Protein Levels Among Individuals With COVID-19 Coronavirus disease 19 infection C-reactive protein test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Frederiksberg University Hospital Denmark 2020-05-04 2020-11-30 APPI2-CV-2020-02, NCT04373798 Phase Not Applicable Not yet recruiting 1 6 Months 3000 Henning Bliddal, DMSc 2020-05-06
An international, investigator-initiated clinical trial to evaluate the efficacy of Lambda in the treatment of patients with COVID-19 infection Coronavirus disease 19 infection peginterferon lambda-1a, Eiger BioPharmaceuticals alone Interferon receptor modulator, Interleukin-29 ligand University of Toronto Eiger BioPharmaceuticals Inc Canada 2020-04-30 Phase Not Applicable Recruiting 1 2020-05-05
An international, investigator-initiated clinical trial to evaluate the efficacy of Lambda in the treatment of patients with COVID-19 infection Coronavirus disease 19 infection peginterferon lambda-1a, Eiger BioPharmaceuticals alone Interferon receptor modulator, Interleukin-29 ligand Mount Sinai Hospital Eiger BioPharmaceuticals Inc US 2020-04-30 Phase Not Applicable Recruiting 0 2020-05-05
COVID-APE: Incidence of Acute Pulmonary Embolism in COVID-19 Patients on CT Angiography and Relationship to D-dimer Levels Coronavirus disease 19 infection, Lung embolism chest CT angiography alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopitaux Universitaires de Strasbourg France 2020-03-03 2020-05-01 7840, COVID-APE, NCT04373486 Phase Not Applicable Recruiting 1 1 Month 160 Aissam LABANI, MD, Catherine ROY, MD, Coralie PAUZET, MD, Françis SCHNEIDER, MD, PhD, François SEVERAC, MD, Ian LEONARD-LORANT, MD, Julie HELMS, MD, PhD, Mickaël OHANA, MD, PhD, Olivier COLLANGE, MD, PhD, Pascal BILBAULT, MD, PhD, Pierre LEYENDECKER, MD, Saïd CHAYER, PhD, HDR, Sébastien MOLIERE, MD, Xavier DELABRANCHE, MD, PhD 2020-05-06
An international, investigator-initiated clinical trial to evaluate the efficacy of Lambda in the treatment of patients with COVID-19 infection Coronavirus disease 19 infection peginterferon lambda-1a, Eiger BioPharmaceuticals alone Interferon receptor modulator, Interleukin-29 ligand Soroka University Medical Center Eiger BioPharmaceuticals Inc Israel 2020-04-30 Phase Not Applicable Recruiting 1 2020-05-05
COVID-SHIELD: COVID-19 prophylaxis with hydroxychloroquine in Front-line Health and Allied-Health Care Workers Coronavirus disease 19 infection hdroxychloroquine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Walter and Eliza Hall Institute of Medical Research Australian Government Australia 2020-04-28 ACTRN12620000501943p, COVID-SHIELD, U1111-1250-4307 Phase 2/Phase 3 Clinical Not yet recruiting 15 2250 Arunee Wilson, Ms Liz Williams, Prof Marc Pellegrini 2020-05-06
VM Spacer plus MDI use in Outpatient ED - COVID-19 Pandemic Coronavirus disease 19 infection, Respiratory disorder Venturi Mask alone Hospital Kuala Lumpur Malaysia 2020-05-01 2021-04-30 54673, NMRR-20-840-54673 Phase Not Applicable Not yet recruiting 1 12 Months 103 Dr. Jacelyn Ong Jia Whey, KOH HOCK PENG 2020-05-06
Health Outcome Rheum Pt on SoC Dur Covid-19 Coronavirus disease 19 infection standard of care alone Selayang Hospital Malaysia 2020-05-04 2020-05-28 54731, NMRR-20-839-54731 Phase Not Applicable Status not specified 1 Dr Lim Shiau Li 2020-05-05
Survey of WHOQoL-Bref Scores Among Persons with Chronic Illness and Public During COVID-19 Pandemic in Malaysia Coronavirus disease 19 infection HOSPITAL TENGKU AMPUAN RAHIMAH KLANG Malaysia 2020-04-29 2020-12-31 54818, NMRR-20-838-54818 Phase Not Applicable Not yet recruiting 1 8 Months Dr. Jacelyn Ong Jia Whey, Dr. Muralitharan Perumal 2020-05-05
McMonty: A reusable personalised ventilation hood: a phase I safety study of a new device (McMonty) in patients with suspected or confirmed COVID-19 Coronavirus disease 19 infection McMonty hood device alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Western Health Sunshine Hospital, University of Melbourne Australia 2020-05-01 ACTRN12620000500954p, McMonty, U1111-1250-6657 Phase 1 Clinical Not yet recruiting 2 20 Dr Forbes McGain 2020-05-06
A study to assess the effectiveness of Ayurvedic formulation in addition to standard of care in COVID-19 positive patients in a tertiary hospital Coronavirus disease 19 infection Tinospora cordifolia stem kashaya alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Medanta The Medicity, Ministry of Ayush Central Council for Research in Ayurvedic Sciences, Council of Scientific and Industrial Research (India) India 2020-04-28 CTRI/2020/04/024882 Phase 3 Clinical Not yet recruiting 1 60 DrSushila Kataria, Mr.Kuldeep K Chauhan 2020-05-06
The CERA Study: The COVID-19 Emergency Response Assessment Study: a survey of the psychological health of frontline doctors in the UK and Ireland during the coronavirus pandemic Coronavirus disease 19 infection North Bristol NHS Trust Royal College of Emergency Medicine UK, Ireland 2020-03-12 2020-10-01 ISRCTN10666798, The CERA Study, V5.0, IRAS 281944 Phase Not Applicable Recruiting 2 6 Months 7000 Dr Tom Roberts 2020-05-06
Treatment of COVID19 : A randomized controlled trial Coronavirus disease 19 infection, Viral pneumonia hydroxychloroquine alone, azithromycin plus hydroxychloroquine Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ministry of Defence India 2020-05-11 CTRI/2020/04/024904 Phase 3 Clinical Not yet recruiting 6 300 AirCmde V K Sashindran, Ajay Kumar, Col Anurag Khera, Col Sanjeevan Sharma, Dheeraj Kumar, Kuldeep Ashta, Rajneesh Thakur, Snehangsh Dash 2020-05-05
HelloBetter Corona: Naturalistic evaluation of an Internet-based psychological training program for mental strain associated with the coronavirus / COVID-19 pandemic Coronavirus disease 19 infection, Psychiatric disorder HelloBetter Corona online training alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Friedrich-Alexander-Universitaet Erlangen-Nuernberg Germany 2020-05-06 172_20 B, DRKS00021588, HelloBetter Corona Phase Not Applicable Not yet recruiting 1 1000 Mathias Harrer 2020-05-05
SROCL: Stroke Rehabilitation Outcome During COVID-19 Lockdown Coronavirus disease 19 infection, Hemorrhagic stroke, Ischemic stroke physical activity engagement alone, rehabilitation therapy alone, upper limb usage alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Zurich Switzerland 2020-04-16 2021-04-30 BASEC-NR. 2020-00761, NCT04373109, SROCL Phase Not Applicable Recruiting 1 12 Months 70 Andreas R Luft, Prof, Janne M Veerbeek, PhD, Jeremia Held, Jeremia PO Held, PhD 2020-05-05
Characteristics of seriously ill COVID-19 patients admitted to a tertiary care center Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences India 2020-05-08 CTRI/2020/04/024914 Phase Not Applicable Not yet recruiting 1 60 Dr Sulagna Bhattacharjee 2020-05-05
Impact of Quarantine on Quality of Life Among Persons Screened for COVID-19 in Malaysia Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) HOSPITAL TENGKU AMPUAN RAHIMAH KLANG Malaysia 2020-04-30 2020-07-29 54817, NMRR-20-837-54817 Phase Not Applicable Not yet recruiting 1 3 Months Dr Yap Soong Yiing, Dr. Muralitharan Perumal 2020-05-05
Clinical research on safety and efficacy of ZingiVir-H as an add on therapy in COVID-19 patients Coronavirus disease 19 infection ZingiVir-H alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Pankajakasthuri Ayurveda Medical College and Post Graduate Center India 2020-04-29 CTRI/2020/04/024883 Phase 4 Clinical Recruiting 1 112 Dr Shan Sasidharan, DrJHareendran Nair 2020-05-05
PRIEST: Evaluation of COVID-19 assessment in emergency departments and ambulance services Coronavirus disease 19 infection, Respiratory tract infection Emergency triage alone Sheffield Teaching Hospitals NHS Foundation Trust NIHR Evaluation, Trials and Studies Coordinating Centre (NETSCC) UK 2012-10-01 2020-07-31 CPMS 12725, IRAS 101138, ISRCTN28342533, PRIEST Phase Not Applicable Recruiting 64 94 Months Prof Goodacre 2020-05-05
Clinical and immunological predictors of SARS-CoV-2 infection and COVID-19 diseases in patients with renal diseases and healthy persons Coronavirus disease 19 infection, Renal disease Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Nierenzentrum Heidelberg Nierenzentrum e.V. Germany 2020-04-06 DRKS00021297, S-224/2020 Phase Not Applicable Recruiting 1 100 Claudia Sommerer 2020-05-05
Antiviral Therapy and Baricitinib for the Treatment of Patients With Moderate or Severe COVID-19 Coronavirus disease 19 infection, Viral pneumonia Variable regimens including baricitinib , hydroxychloroquine , lopinavir + ritonavir , remdesivir Coronavirus non structural protein 8 modulator, HIV protease inhibitor, Jak1 tyrosine kinase inhibitor, Jak2 tyrosine kinase inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Southern California National Cancer Institute US 2020-04-24 2022-04-24 0S-20-3, NCI-2020-02685, NCT04373044, P30CA014089 Phase 2 Clinical Not yet recruiting 0 24 Months 59 Heinz-Josef Lenz, MD, Tali Homsey, BA 2020-05-05
The Prophylactic Effect Of Hydroxychloroquine On Novel Corona Virus Coronavirus disease 19 infection hydroxychloroquine, Tehran Darou, Iran alone, routine care alone Arak University of Medical Sciences and Health Services Iran 2020-04-13 IR.ARAKMU.REC.1398.345, IRCT20151222025660N2 Phase 3 Clinical Recruiting 2 140 Dr Alirza Kamali, Dr. Ramin Parvizrad, Dr.Ramin Parvizrad 2020-05-06
Survive and Thrive: exploring the wellbeing of doctors in a post-COVID-19 era Anxiety disorder, Coronavirus disease 19 infection, Depression University Of Southampton Health Education England UK 2020-01-21 2021-12-31 55747, ISRCTN20867558 Phase Not Applicable Recruiting 1 23 Months 350 Dr Simons 2020-05-06
Epidemiology and Outcome of Ventilator-associated Pneumonia Among Critically Ill COVID-19 Patients Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Semmelweis University Hungary 2020-04-16 2020-08-31 57/2020., NCT04372576 Phase Not Applicable Recruiting 1 4 Months 30 Bence Mogyoródi, MD, Zsolt Iványi 2020-05-06
PredictCovidT: Blood Biomarkers as Predictors of COVID-19 Disease Progression in Recently Infected Kidney Transplant Patients Coronavirus disease 19 infection blood sample alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire De Nice France 2020-04-22 2020-10-22 20-PP-09, NCT04369456, PredictCovidT Phase Not Applicable Recruiting 7 6 Months 115 Alexandre HERTIG, Antoine SICARD, Barbara SEITZ-POLSKI, Christophe MARIAT, Dany ANGLICHEAU, Elisa DEMONCHY, Jean DELLAMONICA, Moglie Le Quintrec, Olivier THAUNAT, Renaud SNANOUDJ, Valerie MOAL, alexandre HERTIG, christophe MARIAT, cynthia CAILLON, sophie Caillard Ohlmann, valerie MOAL 2020-05-06
INVICTUS: Weaning From Mechanical Ventilation for ARDS CovId-19 Patients Guided by Combined Thoracic UltraSound Coronavirus disease 19 infection, Respiratory distress syndrome combined thoracic ultrasound alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire de Toulouse France 2020-04-22 2020-09-22 2020-A00916-33, INVICTUS, NCT04372680, RC31/20/0138 Phase Not Applicable Recruiting 2 5 Months 200 AUDREY BELLOC, Beatrice RIU-POULENC, PH, Béatrice RIU-POULENC, NADERA AINAOUI, PHD, Paul BOURZEIX, Philippe VIGNON, PU PH, Stein SILVA, PU PH 2020-05-06
Efficacy of solnatide to treat pulmonary permeability oedema in SARS-Cov-2 positive patients with moderate-to-severe ARDS Coronavirus disease 19 infection, Pulmonary edema, Respiratory distress syndrome solnatide (liquid aerosol inhalation, pulmonary edema), Apeptico/ Mediolanum alone Sodium channel stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Medical University of Vienna Apeptico Forschung und Entwicklung GmbH Austria 2020-04-11 2020-001244-26, COV-2-SOLNATIDE-20 Phase 2 Clinical Recruiting 1 40 Markus Zeitlinger 2020-05-06
Effect of Atorvastatin in Treatment of COVID-19 Infection Coronavirus disease 19 infection atorvastatin alone, standard treatment alone HMG CoA reductase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Islamic Azad University Iran 2020-04-13 IR.IAU.PS.REC.1399.002, IRCT20200413047062N1 Phase 3 Clinical Recruiting 1 76 Farshad Hashemian, Hamidreza Moezi, Keyhan Mohammadi, Maysa Ghayyem 2020-05-06
Understanding Immunity to SARS-CoV-2, the Coronavirus Causing COVID-19 Coronavirus disease 19 infection, Viral pneumonia Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Stanford University National Institute of Allergy and Infectious Diseases US 2020-04-08 2022-04-30 2U19AI057229, IRB-55689, NCT04373148 Phase Not Applicable Recruiting 0 24 Months 1000 Hena Din, Kari Nadeau, MD, PhD 2020-05-06
Analysis of clinical features of novel coronavirus pneumonia (COVID-19): a medical records based study Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Xiangya Hospital Of Central South University China 2020-03-23 2021-03-23 ChiCTR2000032476 Phase Not Applicable Recruiting 1 12 Months 500 Pinhua Pan 2020-05-06
A medical records based retrospective study for effect of applying individualized Chinese herbal medicine in treatment of patients with novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Chinese herbal medicine alone The Affiliated Hospital of Chengdu University of Traditional Chinese Medicine Science & Technology Department of Sichuan Province China 2020-05-06 2020-07-31 ChiCTR2000032461, ChiMCTR2000003266 Phase Not Applicable Not yet recruiting 3 2 Months 500 Chunguang Xie, Huizhen Chen 2020-05-06
Assessment of effect of levamisole on pneumonia caused by COVID-19 Coronavirus disease 19 infection, Viral pneumonia levamisole alone, symptomatic therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Shiraz University of Medical Sciences Iran 2020-05-04 IR.SUMS.REC.1399.178, IRCT20131215015805N2 Phase 4 Clinical Recruiting 1 50 Dr Mohsen Moghaddami, Dr Payam Peymani, Dr mohsen moghadami, Kamran Bagheri Lankarani 2020-05-06
MeHeS-STAFF Coronavirus disease 19 infection Hospital Tunku Azizah Malaysia 2020-05-01 2020-10-31 54721, NMRR-20-852-54721 Phase Not Applicable Not yet recruiting 1 6 Months Dr LUI SZE CHIANG 2020-05-06
SOAP: School opening in Norway during the COVID-19 pandemic Coronavirus disease 19 infection school opening program alone Norwegian Institute of Public Health Norway 2020-03-18 2020-09-30 ISRCTN44152751, SOAP Phase Not Applicable Not yet recruiting 1 6 Months 125 Prof Atle Fretheim 2020-05-06
ACICOVID: Cardiac Arrest Incidence and Outcome Among Patients With COVID-19 in French ICUs Cardiac arrest, Coronavirus disease 19 infection, Viral pneumonia cardiopulmonary resuscitation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer France 2020-05-31 2020-12-31 2020-CHITS-004, ACICOVID, NCT04373759 Phase Not Applicable Not yet recruiting 35 7 Months 100 Alain Gaffinel, Arnaud Galbois, Arnaud Galbois, MD, Asmaa JOBIC, Benjamin Sztrymf, Benjamin Sztrymf, MD, Camille Foucault, Camille Foucault, MD, Cedric Bruel, Cedric Bruel, MD, Cedric Daubin, Cedric Daubin, MD, Charles Damoisel, MD, Christophe Vinsonneau, Christophe Vinsonneau, MD, Clement Suply, Coralie Gernez, Damien Roux, MD, Damien Vimpere, David Schnell, David Schnell, MD, Didier Thevenin, Didier Thevenin, MD, Dorothee Carpentier, Dorothee Carpentier, MD, Elena Skripkina, Elena Skripkina, MD, Gaetan Plantefeve, Gaetan Plantefeve, MD, Guillaume Geri, Guillaume Geri, MD, Jean-Philippe Suppini, Jean-Pierre Quenot, Jean-Pierre Quenot, MD, Jennifer Brunet, Jobic Asmaa, Jonathan Chelly, Jonathan Chelly, MD, Julie Noublanche, Julien Fournier, Karim Chaoui, MD, Laurent Guérin, Lionel Lamhaut, Ly Van Vong, Ly Van Vong, MD, Marie-Anne Mélone, MD, Marine Paul, Marine Paul, MD, Marjorie Fleury, Maxime Leloup, Maxime Leloup, MD, Michel Kaidomar, Natacha Kapandji, Natacha Kapandji, MD, Nicolas Deye, Nicolas Deye, MD, Nicolas Pichon, Nicolas Pichon, MD, Nicolas Terzi, Nicolas Terzi, MD, Riad Chelha, MD, Richard Descamps, MD, Romain Persichini, Romain Persichini, MD, Saad Nseir, Saad Nseir, MD, Sandie Mazerand, Santiago Freita Ramos, Santiago Freita Ramos, MD, Santiago Picos, Sebastien Ehrminger, MD, Sebastien Jochmans, Sebastien Jochmans, MD, Tai Pham, Thomas Hullin, Thomas Hullin, MD, Toufik Kamel, Toufik Kamel, MD, Vivien Hong Tuan Ha, Vivien Hong Tuan Ha, MD 2020-05-06
Screening of Cancer Patients to Assess Impact of COVID-19 Coronavirus disease 19 infection nasopharyngeal (NP) swab alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The University Health Network Canada 2020-05-04 2020-12-04 CAPCR 20-5337, NCT04373005, U-DEPLOY: RESPONSE Phase Not Applicable Not yet recruiting 1 7 Months 1000 Stephanie Lheureux, M.D. 2020-05-06
HARMONICOV: Human Ab Response and immunomonitoring of COVID-19 Patients Coronavirus disease 19 infection, Respiratory distress syndrome blood sampling alone, immunomonitoring alone, saliva collection alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rennes University Hospital France 2020-05-01 2020-11-01 2020-A01100-39, 35RC20_9795_HARMONICOV, HARMONICOV, NCT04373200 Phase Not Applicable Not yet recruiting 1 6 Months 75 Alexandre MANSOUR, MD, Florian REIZINE, MD, Isabelle GOUIN, MD, Jean-Marc TADIE, MD, PhD, Karin TARTE, MD, PhD, Mathieu LESOUHAITIER, MD, Michel COGNE, MD, PhD, Mikaël ROUSSEL, MD 2020-05-05
COVENTRY: One-Year Quality of Life and Functional Prognosis of COVID-19 Patients in Post-ICU Setting Coronavirus disease 19 infection lung ultrasound alone, muscle ultrasound alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Groupe Hospitalier Paris Saint-Joseph Hôpital Forcilles France 2020-04-16 2021-09-16 COVENTRY, COVENTRY, NCT04373811 Phase Not Applicable Recruiting 1 17 Months 50 Andreia LOPES, PT, Aymeric LE NEINDRE, PT, PhD, Carlos DIAZ, PT, MSc, Gérald CHOUKROUN, MD, Hélène BEAUSSIER, PharmD, PhD, Joséphine COTTIAS, PT, Nesrine BEN NASR, PharmD, PhD, Pascal MEYER, MD 2020-05-06
Study for using sulfate in the prevention and control of novel coronavirus pneumonia (COVID-19) in high and low prevalence communities Coronavirus disease 19 infection, Viral pneumonia hydroxychloroquine sulfate alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Shanghai Public Health Clinical Center China 2020-03-01 2020-09-30 ChiCTR2000032487 Phase 4 Clinical Not yet recruiting 1 7 Months 2000 Lu Xia, Shuihua Lu 2020-05-06
Comparison of three methods of treatment in patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with and without coronavirus positive test (COVID-19) Coronavirus disease 19 infection, Vitamin C deficiency, Vitamin D deficiency routine treatment alone, vitamin C supplement alone, vitamin D supplement alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sabzevar University of Medical Sciences Iran 2020-04-20 IR.MEDSAB.REC.1399.015, IRCT20140305016852N4 Phase 2/Phase 3 Clinical Recruiting 1 30 Ebrahim Shirzade, Fereshteh Ghorat, Somayyeh Nayyeri 2020-05-06
KAPFM Coronavirus disease 19 infection respiratory protective device alone HOSPITAL SERI MANJUNG Malaysia 2020-05-04 2020-12-01 54775, NMRR-20-850-54775 Phase Not Applicable Status not specified 1 6 Months Gobi Hariyanayagam a/l Gunasekaran 2020-05-06
Clinical study on Dabur Chyawanprash as a preventive remedy in pandemic of Covid-19 Coronavirus disease 19 infection Chyawanprash alone Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Dabur India Ltd India 2020-05-15 CTRI/2020/05/024981, DCP-CVD-19/2020/01 Phase Not Applicable Not yet recruiting 5 600 Dr Arun Gupta, Dr Pawankumar Godatwar, Dr Pranita Deshmukh, Dr Raman Ghungralekar, Dr Sanjay Tamoli, Dr Shailesh Deshpande, Dr Vaishali Deshpande 2020-05-06
COVI-DOSE: Weight-Adjusted versus Fixed Low-Doses of Low Molecular Weight Heparin For Venous Thromboembolism Prevention in COVID-19 Coronavirus disease 19 infection, Thromboembolism, Viral pneumonia Variable regimens including dalteparin sodium , enoxaparin sodium , nadroparin calcium , tinzaparin sodium Antithrombin III, Factor IIa antagonist, Factor Xa antagonist, Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Hospital, Nancy, France Ministry of Health, France France 2020-05-31 2020-10-31 2020-001709-21, COVI-DOSE, NCT04373707 Phase 4 Clinical Not yet recruiting 14 5 Months 602 Alessandra Bura-Rivière, Amer Hamadé, Béatrice Terriat, Dominique Stephan, El Mehdi Siaghy, Francis Couturaud, Gabrielle Sarlon-Bartoli, Isabelle Quéré, Julien Bertrand, Nicolas Meneveau, Olivier Sanchez, Patricia Costa, Patrick Mismetti, Saïda Khaled-Jousselin, Res Proj Man, Simon Soudet, Stéphane Zuily, Stéphane Zuily, MD, PhD, Wael Younès, Yohann Bernard, Res Proj Man 2020-05-06
Homoeopathy as adjuvant in management of Covid-19 infection Coronavirus disease 19 infection, Viral pneumonia Homoeopathic medicines alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Naiminath Homoeopathic Medical College, Hospital and Research Centre India 2020-05-10 CTRI/2020/05/024969 Phase 2/Phase 3 Clinical Not yet recruiting 1 100 Dr Anil Khurana, Dr Debadatta Nayak, Prof Dr Pradeep Kumar Gupta 2020-05-06
COVID'HEMOS: Study of the Vascular Compartment and Hypercoagulability During Coronavirus Infection COVID-19 Coronavirus disease 19 infection blood sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Boisguillaume France 2020-04-09 2020-07-31 2020/0104/OB, COVID'HEMOS, NCT04367662 Phase Not Applicable Recruiting 1 3 Months 100 Francois CARON, Pr, Julien BLOT, Manuel ETIENNE, Pr, Paul BILLOIR, Pharmacist, Paul BILLOIR, pharmacist, Véronique LE CAM, MD 2020-05-06
COVID-19 social study: the effects of quarantine on mental health Coronavirus disease 19 infection, Psychiatric disorder Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University College London Nuffield Foundation UK 2020-03-23 2020-12-31 12467/005, ISRCTN97041334 Phase Not Applicable Recruiting 1 9 Months 1000000 Ms Vas James 2020-05-06
Developing and validating of clinical prediction model for novel coronavirus pneumonia (COVID-19) patients progressing to critical type, acute respiratory distress syndrome and death: a medical records based study Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tongji Medical College China 2020-05-01 2021-04-30 ChiCTR2000032527 Phase Not Applicable Not yet recruiting 1 12 Months 8500 Shusheng Li, Yi Bian 2020-05-06
Enhanced Hood PPE to Minimize COVID-19 Transmission to Front-line Health Care Workers Coronavirus disease 19 infection modified IPAC-UHN PPE alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) The University Health Network Canada 2020-05-07 2020-08-31 20-5448, NCT04373096 Phase Not Applicable Not yet recruiting 1 3 Months 42 Anahi Perlas, MD,FRCPC, Mehdi Soheili, Rongyu Jin 2020-05-06
MUM: Global Mental Health of Urban Mothers Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder Web-based psychosocial peer-to-peer support alone Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Karolinska Institutet Swiss National Science Foundation Hong Kong, China, Sweden 2020-06-30 2023-06-30 MUM, NCT04363177, P2SKP3_187728 Phase Not Applicable Not yet recruiting 3 36 Months 300 Ewa Andersson, PhD, Hsuan-Ying Huang, PhD, Liping Zhu, PhD 2020-05-06
A clinical study of anti-SARS-CoV-2 antibodies for the treatment of COVID-19 Coronavirus disease 19 infection anti-SARS-CoV-2 antibodies (COVID-19), AbCellera/Eli Lilly alone AbCellera Biologics Inc 2020-07-31 Phase Not Applicable Planned 0 2020-05-05
Effect of curcumin-piperine supplementation on disease duration, severity and clinical signs, and inflammatory factors in patients with coronavirus (COVID-19): A randomized, double-blind, placebo-controlled clinical trial study Coronavirus disease 19 infection curcumin capsules plus piperine capsules Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Isfahan University of medical Sciences Iran 2020-05-04 IR.MUI.MED.REC.1399.049, IRCT20121216011763N46 Phase Not Applicable Recruiting 1 100 Gholamreza Askari, Shaghayegh Haghjou 2020-05-06
Application of pulmonary rehabilitation exercise in the treatment of novel coronavirus pneumonia (COVID-19) patients during convalescence period Coronavirus disease 19 infection, Viral pneumonia pulmonary rehabilitation exercise alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Huazhong University of Science and Technology Beijing Chao-Yang Hospital China 2020-05-01 2020-05-31 ChiCTR2000032457 Phase Not Applicable Not yet recruiting 1 1 Month 60 Wang Feng, Zhang Jianchu 2020-05-06
PLASCOSSA: Efficacy of Convalescent Plasma Therapy in the Early Care of COVID-19 Patients Coronavirus disease 19 infection SARS-CoV-2 convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Direction Centrale du Service de Sante des Armees University Hospital, Grenoble France 2020-05-31 2021-05-31 2020-A01166-33, NCT04372979, PLASCOSSA Phase 3 Clinical Not yet recruiting 4 12 Months 80 Catherine VERRET, Christophe MARTINAUD, Christophe MARTINAUD, PU PH, Christophe RENARD, Cécile FICKO, Damien RICARD, Fabien DUTASTA, Hervé FOEHRENBACH, Hélène SAVINI, Jean-Luc BOSSON, Jean-Paul HYRIEN, Katia AVMART, Marc ALETTI 2020-05-06
Effects of convalescent plasma in COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome COVID-19 convalescent plasma alone, standard national guideline treatment alone Oroumia University of Medical Sciences Urmia University of Medical Sciences Iran 2020-05-04 IR.UMSU.REC.1399.030, IRCT20200501047258N1 Phase 2/Phase 3 Clinical Recruiting 1 120 Iraj Mohebbi, Rahim Asgari, Rahim Asghari 2020-05-06
Clinical trial on Immunity and antiviral for quarantine patients of COVID-19 Coronavirus disease 19 infection, Immune disorder MyVir alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) MiLab LifeSciences (P) Ltd India 2020-05-11 CT/MiLab/MyVir/2020, CTRI/2020/05/024967 Phase 4 Clinical Not yet recruiting 1 30 Dr CR Jayanthi, MrLAKSHMANA PERUMAL SPT 2020-05-06
A Randomized Controlled Trial for the Effects of Low-Oxygen Consumption Instruction on the Prognosis of Patients with Novel Coronavirus Pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia low oxygen consumption alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Shanghai Public Health Clinical Center China 2020-03-01 2020-05-01 ChiCTR2000032456 Phase Not Applicable Completed 1 2 Months 100 Shuihua Lu, Yang Yang 2020-05-05
TREAT NOW: Trial of Early Therapies During Non-hospitalized Outpatient Window for COVID-19 Coronavirus disease 19 infection hydroxychloroquine alone, lopinavir + ritonavir alone HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Vanderbilt University Medical Center, US AbbVie Inc US 2020-05-01 2021-05-01 200827, NCT04372628, TREAT NOW Phase 2 Clinical Not yet recruiting 0 12 Months 900 Adit A Ginde, MD, Lani L. Finck, Margaret A. Hays, Margaret Hays, Nathan I. Shapiro, M.D., Nathan L Shapiro, MD, Sharon Hayes, RN, Todd Rice, MD, Todd W. Rice, M.D., Todd W. Rice, MD 2020-05-05
The use of topical Povidone Iodine (PVP-I) oropharyngeal and intranasal application during the current coronavirus pandemic as a potential measure to reduce viral transmission Coronavirus disease 19 infection Povidone Iodine alone, standard oral antiviral therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) WIN MEDICARE PVTLTD Drugs Control Administration India 2020-05-05 CTRI/2020/05/024962 Phase Not Applicable Not yet recruiting 1 96 Dr Sumita Shankar 2020-05-06
COST ACTION: Study for the Evaluation of Specific Antibodies Anti Covid-19 Linked to Covid-19 Infection, Symptoms and Genetic Expression of ACE2 Polymorphisms in Patients Coronavirus disease 19 infection BioMedomics COVID-19 IgM-IgG Rapid Test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ospedale San Paolo Italy 2020-03-30 2020-09-30 2020/ST/057, COST ACTION, NCT04367402 Phase Not Applicable Recruiting 1 6 Months 600 Stefano Centanni, Full Professor 2020-05-05
Home Pulse Oximeter Use in Patients With COVID-19 Coronavirus disease 19 infection pulse oximetry alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Swedish Hospital US 2020-03-30 2020-04-22 2020032301, NCT04373161 Phase Not Applicable Completed 0 211 Kaushal Majmudar, Sonia Shah, DO 2020-05-06
MIA-COVID-19: Minimal Invasive Autopsies to Investigate Changes in Deceased COVID-19 Patients Coronavirus disease 19 infection CT-scan alone Jessa Hospital Antwerp University Hospital, Universiteit Hasselt Belgium 2020-04-14 2020-12-31 JESSAH_COVID-19_MIA, MIA-COVID-19, NCT04366882 Phase Not Applicable Recruiting 1 8 Months 45 Jan Vanrusselt, MD, Janneke Cox, MD, PhD 2020-05-06
A study for the mental health status of novel coronavirus pneumonia (COVID-19) convalescent patients and first-line medical staff and Isolate residents and Hospital staffand the intervention strategy of psychological crisis in Ningxia Coronavirus disease 19 infection psychological crisis intervention alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ningxia Medical University China 2020-04-28 2021-12-31 ChiCTR2000032455 Phase 0 Clinical Recruiting 1 20 Months 140 Jiang Hong, Ma Xin-rong 2020-05-06
US3R: Health Care Use During the COVID-19 Crisis Coronavirus disease 19 infection online questionnaire alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universite Catholique de Louvain Belgium 2020-05-01 2021-10-31 NCT04372030, US3R, US3R Phase Not Applicable Not yet recruiting 1 18 Months 10000 Dominique Vanpee, MD, Sandy Tubeuf, PhD 2020-05-06
Economic burden of COVID-19 in Malaysia Coronavirus disease 19 infection Government of Malaysia Malaysia 2020-05-04 2022-12-19 54823, NMRR-20-865-54823 Phase Not Applicable Not yet recruiting 1 31 Months Dr Amirah binti Azzeri, Dr Maznah Dahlui 2020-05-05
Clinical characteristics of renal patients with COVID-19 infection Coronavirus disease 19 infection, Renal failure Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Nierenzentrum Heidelberg Germany 2020-04-06 DRKS00021295, S-223/202 Phase Not Applicable Recruiting 1 100 Claudia Sommerer 2020-05-05
A multicenter, randomized, open comparative clinical trial of the drug Favipiravir in patients hospitalized with COVID-19 Coronavirus disease 19 infection favipiravir alone RNA polymerase inhibitor ChemRar High Tech Center, Russian Direct Investment Fund Russian Federation 2020-04-28 Phase 2 Clinical Recruiting 3 330 2020-05-05
Convalescent Plasma for the Treatment of Patients With COVID-19 Coronavirus disease 19 infection, Dyspnea, Respiratory failure COVID-19 convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Colorado, Denver, US US 20-0990, NCT04372368 Phase Not Applicable Recruiting 0 John D Beckham, MD 2020-05-06
A clinical trial of XRx-101 for prevention of acute kidney injury due to coronavirus/COVID-19 infection Coronavirus disease 19 infection, Renal injury oxypurinol (acute kidney injury/lung injury/COVID-19), XORTX Therapeutics alone Xanthine oxidase inhibitor XORTX Therapeutics Inc Phase Not Applicable Planned 0 2020-05-05
Convalescent Plasma to Limit SARS-CoV-2 Associated Complications Coronavirus disease 19 infection SARS-CoV-2 convalescent plasma (HCIP) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Johns Hopkins University Bloomberg Philanthropies, University of Maryland US 2020-05-11 2023-01-31 CSSC-004, IRB00247590, NCT04373460 Phase 2 Clinical Not yet recruiting 0 32 Months 1344 David J Sullivan, MD, David Sullivan, MD 2020-05-05
SQuISH-COVID: SQuISH-COVID: A Pilot Study Coronavirus disease 19 infection, Sepsis SeptiScan System alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cytovale Inc Biomedical Advanced Research and Development Authority (BARDA) US 2020-04-07 2020-05-29 CV-CLN-003, NCT04372472, SQuISH-COVID Phase Not Applicable No longer recruiting 0 1 Month 300 Hollis R O'Neal, Jr., MD, MSc 2020-05-05
COVID Liver Coronavirus disease 19 infection, Liver disease Selayang Hospital Malaysia 2020-05-20 2020-06-30 54896, NMRR-20-856-54896 Phase Not Applicable Status not specified 1 1 Month Dr Tan Soek Siam 2020-05-05
CoNFINE: Limitations of social life in the context of the COVID-19 pandemic - Effects on physical performance and health-related quality of life of older people Coronavirus disease 19 infection Milon-circuit training alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Carl Von Ossietzky Universität Oldenburg Germany 2020-04-20 2020-061, CoNFINE, DRKS00021432 Phase Not Applicable Recruiting 1 100 Jessica Koschate, Tania Zieschang 2020-05-05
Evaluation of the Fluid Response of SARS-CoV-2 (COVID-19) Patients in Intensive Care; Pleth Variability Index Coronavirus disease 19 infection fluid management alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Erzincan University Turkey 2020-05-05 2020-06-15 EBYU COVİD PVI, NCT04373213 Phase Not Applicable Not yet recruiting 1 1 Month 30 ILKE KUPELI 2020-05-05
Max Ivermectin - COVID-19 Study Versus Standard of Care Treatment for COVID-19 Cases. A Pilot Study Coronavirus disease 19 infection ivermectin alone, standard treatment alone Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Max Healthcare Institute Ltd, India India 2020-04-25 2020-07-25 MHC-COVID-19- INV- ACT-BHR, NCT04373824 Phase 2 Clinical Recruiting 1 3 Months 50 Rajesh Saxena, MBA, Ram Shankar Mishra, DNB, FRCP, Sandeep Budhiraja, MRCP, FACP 2020-05-05
Duvelisib to Combat COVID-19 Coronavirus disease 19 infection, Respiratory failure duvelisib alone Phosphoinositide-3 kinase delta inhibitor, Phosphoinositide-3 kinase gamma inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Washington University School of Medicine, US Verastem Oncology US 2020-06-30 2021-12-31 04-28-20-DIPERSIO, NCT04372602 Phase 2 Clinical Not yet recruiting 0 18 Months 25 Erik Dubberke, M.D., MSPH, John DiPersio, M.D., Ph.D., Mark Fiala, MSW 2020-05-05
CHIC: Covid High-intensity Immunosuppression in Cytokine release syndrome Coronavirus disease 19 infection, Viral pneumonia methylprednisolone plus tocilizumab Zuyderland Medical Center, Heerlen Netherlands 2020-04-23 2020-07-31 CHIC, NL8551 Phase Not Applicable Recruiting 1 3 Months 160 Sofia Ramiro 2020-05-06
BREATH: Breath Regulation and Yogic Exercise An Online Therapy for Calm and Happiness Anxiety disorder, Coronavirus disease 19 infection, Depression, Insomnia Health Enhancement Program alone, Sudarshan Kriya Yoga (SKY) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Lawson Health Research Institute Art Of Living foundation Canada 2020-05-10 2021-06-30 115855, BREATH, NCT04368676 Phase 0 Clinical Not yet recruiting 1 13 Months 60 Akshya Vasudev, MBBS, MD, Akshya Vasudev, MD, Emily Ionson, Hr.BSC 2020-05-06
CoVUm: Host-pathogen Interactions, Immune Response, and Clinical Prognosis at COVID-19 - the CoVUm Trial Coronavirus disease 19 infection blood sampling alone, urine and feces sampling alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Umea University Västerbotten County Council, Sweden Sweden 2020-04-28 2026-04-14 COVUM, CoVUm, NCT04368013 Phase Not Applicable Not yet recruiting 1 71 Months 400 Alicia Edin, M.D., Clas Ahlm, Professor, Johan Normark, Docent 2020-05-06
Hydroxychloroquine for Post-Exposure Prophylaxis of COVID-19 among naval personnel: a placebo-controlled, randomized, clinical trial Coronavirus disease 19 infection hydroxychloroquine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) University of Kelaniya Sri Lanka Navy, Ministry of Defense, State Pharmaceuticals Manufacturing Corporation of Sri Lanka Sri Lanka 2020-05-04 2020-05-31 P/22/04/2020, SLCTR/2020/011, U1111-1251-3613 Phase 4 Clinical Not yet recruiting 1 400 Niriella MA 2020-05-06
COVUSt: COVID19 ultrasound triage Coronavirus disease 19 infection Point-of-Care Ultrasound alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Isala Netherlands 2020-04-14 2020-06-01 COVUSt, NL8543 Phase Not Applicable Recruiting 1 1 Month 50 Svenja Haak 2020-05-06
PAPR: Prone Positioning in Awake Patients With COVID-19 Requiring Hospitalization Coronavirus disease 19 infection Prone Positioning alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Utah 2020-04-30 2021-01-31 IRB_00132123, NCT04368000, PAPR Phase Not Applicable Not yet recruiting 0 9 Months 60 Stacy A Johnson, MD 2020-05-05
ARMOR Study: COVID-19 Seroprevalence Among Healthcare Workers Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Columbia University US 2020-04-18 2021-10-31 AAAS9998, NCT04367857 Phase Not Applicable Recruiting 0 18 Months 1000 Brett Gray, Magdalena Sobieszczyk, MD, MPH 2020-05-06
The PRONE study: Sleep position related to hospital length of stay in admitted COVID-19 patients Coronavirus disease 19 infection Sleep Position Trainer alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Franciscus Gasthuis & Vlietland 2020-04-17 2021-04-17 NL8538, The PRONE study Phase Not Applicable Planned 0 12 Months 342 Vivan Baggen 2020-05-06
A randomized, double-blind, placebo-controlled trial of intravenous plasma-purified alpha-1 antitrypsin for severe COVID-19 illness Coronavirus disease 19 infection plasma-purified alpha-1 antitrypsin alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Royal College of Surgeons in Ireland Health Research Board Clinical Research Coordination Ireland Ireland 2020-04-24 2020-001391-15, V1Mar2020 Phase 2 Clinical Recruiting 1 Mandy Jackson 2020-05-06
NEUMONIA: Neurological Manifestations of COVID-19 and Indications of an Association with Respiratory Failure Coronavirus disease 19 infection, Respiratory failure neurological examination alone Zuyderland Medical Center, Heerlen Netherlands 2020-04-28 2020-07-31 METCZ20200077, NEUMONIA, NL8536 Phase Not Applicable Recruiting 1 3 Months 285 M. Beckers 2020-05-06
Functional status and health status in COVID-19 patients pre and post rehabilitation Coronavirus disease 19 infection rehabilitation alone CIRO TRADE PRIVATE LIMITED Netherlands 2020-03-30 2020-11-30 METC 2020-1340, NL8535 Phase Not Applicable Recruiting 1 8 Months 30 Anouk Vaes 2020-05-06
PredictCovid-D: Blood Biomarkers as Predictors of COVID-19 Disease Progression in Recently Infected Chronic Hemodialysis Patients Coronavirus disease 19 infection, Renal disease blood sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire De Nice France 2020-04-22 2021-02-22 20-PP-08, NCT04371510, PredictCovid-D Phase Not Applicable Recruiting 1 10 Months 115 SICARD Antoine, SICARD Antoine, Ph, sicard antoine, ph 2020-05-06
COVID-19 Health Messaging to Underserved Communities Coronavirus disease 19 infection Messaging alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), African Ancestry, European Ancestry National Bureau of Economic Research Inc Harvard University, Massachusetts General Hospital, Massachusetts Institute of Technology, Stanford University, Yale University 2020-05-08 2021-06-30 2003000118, NCT04371419 Phase Not Applicable Not yet recruiting 0 13 Months 20000 2020-05-06
Evaluation of the therapeutic effect of a combination drug including apocynin, niacin, and tannin on COVID-19 Cardiovascular disease, Coronavirus disease 19 infection, Respiratory disease, Viral pneumonia current standard treatment alone, Variable regimens including apocynin , niacin , tannin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Isfahan University of medical Sciences Iran 2020-04-25 IR.MUI.MED.REC.1399.050, IRCT20200418047122N1 Phase 2/Phase 3 Clinical Recruiting 1 80 Dr Hossein Khanahmad, Dr Mehrdad Zeinalian, Dr Pourajam, Dr Shirani 2020-05-06
Usage of topical lignocaine to decrease the gag reflex while sampling for Covid-19: Does it affect the yield of specimen? Coronavirus disease 19 infection qualitative reverse transcription real-time Polymerase Chain Reaction test alone, lidocaine plus lignocaine Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences India 2020-05-05 CTRI/2020/05/024983 Phase 2 Clinical Not yet recruiting 1 30 Alok Thakar, Dr Anupam Kanodia 2020-05-06
Effects of using hydroxychloroquine and azithromycin in the treatment of confirmed COVID-19 positive patients Coronavirus disease 19 infection azithromycin plus hydroxychloroquine Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Medical Sciences, Raipur India 2020-05-15 CTRI/2020/05/024982 Phase 2 Clinical Not yet recruiting 1 50 Dr PUGAZHENTHAN T 2020-05-06
Evaluation of the Sleep Hygiene in the Lebanese Population During the COVID-19 Confinement Period Coronavirus disease 19 infection Sleep Hygiene Index questionnaire alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Saint Joseph's University Lebanon 2020-04-30 2020-09-30 CEHDF1650, NCT04372043 Phase Not Applicable Not yet recruiting 1 5 Months 1200 Jad Costa, Jeanine El Helou, MD, MSc 2020-05-05
CARDICoVRISK: Predictors of Cardiovascular Risk in COVID-19 Patients During Acute Disease and at Short-Term Follow-up Cardiovascular disease, Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Istituto Auxologico Italiano Italy 2020-04-30 2020-09-10 CARDICoVRISK, CE_2020_03_26_02, NCT04371289 Phase Not Applicable Not yet recruiting 1 4 Months 5500 Gianfranco Parati, MD, PhD 2020-05-06
PREVENT: Prophylactic Benefit of Hydroxychloroquine in COVID-19 Cases With Mild to Moderate Symptoms and in Healthcare Workers With High Exposure Risk Coronavirus disease 19 infection hydroxychloroquine sulfate alone Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Texas Cardiac Arrhythmia Research Foundation US 2020-06-30 2021-07-31 NCT04371926, PREVENT, TCAI_PREVENT Phase Not Applicable Not yet recruiting 0 13 Months 64 Andrea Natale, Andrea Natale, MD, Angel Mayedo, MD, Bryan MacDonald, MD 2020-05-06
Effect of of Inhalation of Thyme Oil in COVID-19 Coronavirus disease 19 infection Variable regimens including hydroxychloroquine , lopinavir + ritonavir , thyme HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shoushtar School of Medical Sciences Iran 2020-05-04 IR.SHOUSHTAR.REC.1399.005, IRCT20200426047212N1 Phase 2/Phase 3 Clinical Recruiting 1 48 Ali Hatami, Barat Barati, Hassan Hassanzadeh Namin, Mohammad Nikzadian 2020-05-06
MG-COVID: Efficacy of Azithromycin-associated Hydroxychloroquine Therapy Given in General Practice in Early-stage Disease in COVID-19 Patients Coronavirus disease 19 infection standard of care alone, Plaquenil plus azithromycin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Assistance Publique Hopitaux de Paris France 2020-05-02 2020-09-02 2020-001702-35, APHP200447, MG-COVID, NCT04371406 Phase 3 Clinical Not yet recruiting 1 4 Months 2770 Alix PENEL, Julie CHASTANG, Dr, Sarra POCHON 2020-05-04
Study the effectiveness of concomitant use of vitamin C, metformin, azithromycin and doxycycline on improving patients with COVID-19 Coronavirus disease 19 infection Variable regimens including azithromycin , doxycycline hyclate , metformin hydrochloride , vitamin C AMP activated protein kinase stimulator Kermanshah University of Medical Sciences Iran 2020-05-09 IRCT20200418047121N1, ir.kums.rec.1399.079 Phase 3 Clinical Not yet recruiting 1 40 Dr. Faizullah Mansouri, Dr. Farid Najafi, Dr. Kamran Mansouri 2020-05-06
Trifluoperazine Effectiveness in Treatment of Coronavirus Coronavirus disease 19 infection standard care alone, trifluoperazine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rasht University of Medical Sciences Iran 2020-05-04 2020-05-27 IR.GUMS.REC.1399.021, IRCT20200329046892N1 Phase 2/Phase 3 Clinical Recruiting 1 70 Nematollah Ahangar, Seyed Ali Alavi 2020-05-05
Genetics of COVID-19 Susceptibility and Manifestations Coronavirus disease 19 infection SNP chip assay alone, genome sequencing alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) National Human Genome Research Institute National Institutes of Health Clinical Center US 2020-05-08 2025-06-01 20-HG-0090, 200090, NCT04371432 Phase Not Applicable Recruiting 0 60 Months 2500 Julie Sapp, Leslie G Biesecker, M.D. 2020-05-06
CATCH COVID-19: Comparison of the Efficacy of Rapid Tests to Identify COVID-19 Infection Coronavirus disease 19 infection Serology test alone, Viral RNA test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Texas Cardiac Arrhythmia US 2020-05-31 2021-06-30 CATCH COVID-19, NCT04372004, TCAI_CATCH COVID-19 Phase Not Applicable Not yet recruiting 0 13 Months 100 Andrea Natale, Executive Medical Director, Deb Cardinal, RN MBA, MITRA Mohanty, MD 2020-05-05
Direct evidence of rectal cancer patient infected with novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Zhangnan Hospital China 2020-05-06 2020-05-16 ChiCTR2000032514 Phase Not Applicable Not yet recruiting 1 13 Jiang Congqing 2020-05-05
COVISLEEP: Impact of Neck Inspiratory Muscle Activation During Sleep in ICU Patients After a COVID-19 ARDS Coronavirus disease 19 infection, Respiratory distress syndrome neck inspiratory muscle (NIM) activation alone, polysomnography (PSG) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Bordeaux France 2020-04-30 2020-09-30 CHUBX 2020/14, COVISLEEP, NCT04371029 Phase Not Applicable Not yet recruiting 1 5 Months 25 Léo GRASSION, Dr, Renaud PREVEL, Dr 2020-05-06
Provider Burnout During COVID-19 Acute stress disorder, Coronavirus disease 19 infection coping strategies video alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Pittsburgh US 2020-04-29 2020-10-29 NCT04370938, STUDY20040051 Phase Not Applicable Recruiting 0 6 Months 250 Sara Myers, MD, Sara P Myers, MD, PhD 2020-05-06
Recruit Blood Donors Via SMS During Epidemic of COVID-19 Coronavirus disease 19 infection blood donation SMS alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Guangzhou Blood Center China 2020-04-30 2020-05-10 NCT04370886, RECRUIT BLOOD DONORS VIA SMS Phase Not Applicable Recruiting 1 394578 2020-05-05
Impact of the COVID-19 Pandemic on Diet Quality and Food Insecurity: a NutriQuebec Sub-study Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universite Laval Canada 2020-04-16 2020-05-07 2018-042PHASE IIA6/09-04-2020, NCT04371848 Phase Not Applicable No longer recruiting 1 2465 Benoît Lamarche 2020-05-04
A randomized, double-blind, placebo-controlled, Phase II/III trial to determine the safety and efficacy of DSTAT in COVID-19 patients with acute lung injury (ALI) Acute lung injury, Coronavirus disease 19 infection dociparstat (iv, AML/acute lung injury/COVID-19), Chimerix alone CXCR4 chemokine modulator, Cathepsin G inhibitor, Complement cascade inhibitor, Elastase inhibitor, Heparin agonist, High mobility group protein B1 inhibitor, L selectin antagonist, P selectin antagonist, Platelet factor 4 ligand inhibitor, Stromal cell-derived factor 1 ligand modulator Chimerix Inc 2020-04-29 Phase 2/Phase 3 Clinical Recruiting 0 524 2020-05-05
Effect of Formoterol in treatment of covid19 Coronavirus disease 19 infection formoterol(Medochemie Company) alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) National Research Institute of Tuberculosis and Lung Diseases Iran 2020-04-18 IR.SBMU.NRITLD.REC.1398.003, IRCT20170210032478N3 Phase 3 Clinical Recruiting 1 50 Dr. Parisa Farnia, Fariba Ghorbani, Giti Pourdoulat, Guitti Pourdowlat 2020-05-05
Study on data management and diagnosis-treatment mode of TCM intervention for novel coronavirus pneumonia (COVID-19) convalescence Coronavirus disease 19 infection, Viral pneumonia TCM intervention alone Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, National Science and Technology Support Plan of the People's Republic of China China 2020-04-29 2021-04-22 2020YFC0845000, ChiCTR2000032480, ChiMCTR2000003257 Phase Not Applicable Not yet recruiting 5 11 Months 1000 Liu Baoyan, Liu Jia 2020-05-05
Effect of interactive psycho-educational interventions on patients infected with COVID-19 Coronavirus disease 19 infection psycho-educational interventions alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shiraz University of Medical Sciences Iran 2020-05-14 IR.SUMS.REC.1399.012, IRCT20130616013690N7 Phase Not Applicable Not yet recruiting 1 50 Maryam Shaygan, Younes Ghasemi 2020-05-05
Evaluation of the efficacy of melatonin tablets as auxiliary medication in accelerating the improvement of the COVID-19 symptoms and clinical findings Coronavirus disease 19 infection hydroxychloroquine plus melatonin Gonabad University of Medical Sciences Iran 2020-04-14 IR.GMU.REC.1399.016, IRCT20200408046988N1 Phase 2/Phase 3 Clinical Recruiting 1 60 Najmeh Davoodian, Najmeh Davoudian, Shayla khosravan 2020-05-05
FORCE: Avdoralimab an Anti-C5aR Antibody, in Patients With COVID-19 Severe Pneumonia Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia avdoralimab (IPH5401) alone CXCR1 chemokine antagonist, Complement C5a receptor antagonist, IL-8 receptor antagonist, Monocyte chemotactic protein 1 ligand inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux De Marseille Innate Pharma SA France 2020-04-27 2020-10-27 2020-21, FORCE, NCT04371367 Phase 2 Clinical Recruiting 1 6 Months 108 Emilie Garrido-Pradalie, Julien CARVELLI, Julien CARVELLI, MD, Nicolas, SCHLEINITZ, MD 2020-05-05
Clinical trial study on the therapeutic effect of Tenofovir besides Kaletra and Chloroquinein in patients with Coronavirus disease 2019 (COVID-19) Coronavirus disease 19 infection Variable regimens including alfamed tenofovir , chloroquine , lopinavir + ritonavir HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ahvaz University of Medical Sciences Iran 2020-04-18 IR.AJUMS.REC.1399.082, IRCT20200422047168N1 Phase 2/Phase 3 Clinical Recruiting 1 60 Ali Akbar Shayesteh, Ali akbar Shayesteh, Zahra Shokati 2020-05-06
KILLER: Povidone-iodine Mouthwash, Gargle, and Nasal Spray to Reduce Naso- Pharyngeal Viral Load in Patients With COVID-19 Coronavirus disease 19 infection povidone-iodine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire De Poitiers Etablissement D’Hospitalisation France 2020-05-01 2020-08-01 KILLER, KILLER, NCT04371965 Phase 2 Clinical Not yet recruiting 1 3 Months 24 Olivier MIMOZ, Professor, Sabrina SEGUIN, CRA 2020-05-05
Evaluation of the effect of Iranian medicine product, Algro, on patients with Coronavirus 19 Coronavirus disease 19 infection Algro alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bagheiat-allah University of Medical Sciences Iran 2020-05-04 2020-05-19 IR.BMSU.REC.1399.038, IRCT20160131026298N3 Phase 2/Phase 3 Clinical Recruiting 1 80 Ahmad Reza Sharifi Olounabadi, REZAMOHTASHAMI, AHMAD REZA SHARIFI OLOUNABADI, Reza Mohtashami 2020-05-05
SirCO-1: Sirolimus in COVID-19 Phase I Coronavirus disease 19 infection Standard medical care alone, sirolimus alone mTOR inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Thomas Jefferson University US 2020-05-31 2020-08-31 15680, NCT04371640, SirCO-1 Phase 1 Clinical Recruiting 0 3 Months 40 Angela C Pallotto, RN, BSN, Edwin Lam, PharmD, Walter K Kraft, MD 2020-05-06
Outcomes of Covid Protective Measures in Endoscopy Coronavirus disease 19 infection Covid PCR tests alone, endoscopy alone, protective protocol implementation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundación Pública Miguel Servet Spain 2020-04-27 2020-07-27 2020-COCHE, NCT04371354 Phase Not Applicable Not yet recruiting 2 3 Months 100 Juan J Vila, PhD, Ruth Garcia 2020-05-06
Evaluation effect of treatment with im (intramuscular) D3 on clinical, paraclinical symptoms and signs and inhospital outcome at patient admitted with COVID-19 Coronavirus disease 19 infection vitamin D alone Shahrood University of Medical Sciences Iran 2020-05-21 IR.SHMU.REC.1399.013, IRCT20200411047024N1 Phase 1/Phase 2 Clinical Not yet recruiting 1 100 Erfan Kazemi, Mohammad Hassan Emamian, hossien sheybani 2020-05-05
Safety and Effectiveness of Mesenchymal Stem Cells in the Treatment of Pneumonia of Coronavirus Disease 2019 Coronavirus disease 19 infection, Viral pneumonia hormones therapy alone, mechanical ventilation alone, oxygen therapy alone, supportive therapy alone, oseltamivir plus umbilical cord mesenchymal stem cells Exo-alpha sialidase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Fuzhou general hospital China 2020-03-01 2022-12-31 MSC-COVID-2020, NCT04371601 Phase 0 Clinical No longer recruiting 1 34 Months 60 Jianming Tan Tan, M.D and Ph.D 2020-05-05
A Study to Evaluate the Efficacy and Safety of Tocilizumab in Hospitalized Participants With COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia standard of care alone, tocilizumab (intravenous), Roche/Chugai alone IL-6 receptor antagonist, IL-6 receptor modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Genentech Inc 2020-05-08 2020-10-05 ML42528, NCT04372186 Phase 3 Clinical Not yet recruiting 0 4 Months 379 Clinical Trials 2020-05-06
The COVID-ICU Healthcare Professional Study Coronavirus disease 19 infection electronic questionnaire on views and experiences alone Healthy volunteers accepted Oslo University Hospital Norway 2020-04-30 2021-04-30 136144, NCT04372056 Phase Not Applicable Not yet recruiting 1 12 Months 2200 Irene LIe, Irene Lie, Siv Stafseth 2020-05-06
Hydroxychloroquine and Zinc With Either Azithromycin or Doxycycline for Treatment of COVID-19 in Outpatient Setting Coronavirus disease 19 infection Variable regimens including azithromycin , doxycycline , hydroxychloroquine , zinc sulfate Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) St. Francis Hospital, New York US 2020-04-28 2020-12-31 20-21, NCT04370782 Phase 4 Clinical Not yet recruiting 0 8 Months 750 Avni Thakore MD, Avni Thakore, MD, Elizabeth Haag, RN, Elizabeth S Haag, RN 2020-05-05
Risk Factors, Clinical Characteristics and Outcomes of Acute Infection With Coronavirus 2019 (COVID-19) In Children Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) St Jude Children's Research Hospital US 2020-04-27 2022-06-30 COVID-19, NCT04371315 Phase Not Applicable Recruiting 0 26 Months 400 Diego Hijano, MD 2020-05-05
Tocilizumab for Patients With Cancer and COVID-19 Disease Coronavirus disease 19 infection, Viral pneumonia tocilizumab (intravenous), Roche/Chugai alone IL-6 receptor antagonist, IL-6 receptor modulator Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Cancer Institute US 2020-05-01 2022-01-01 NCI-2020-02987, NCT04370834, TRC-10446 Phase 2 Clinical Not yet recruiting 0 20 Months 200 Richard F Little 2020-05-06
Study of Resilience and Loneliness in Youth (18 to 25 Years Old) During the SARS-CoV2 Pandemic Lock-down Measures Coronavirus disease 19 infection, Psychiatric disorder Healthy volunteers accepted, Young Adults (18-44 yrs) Erasme Hospital King Baudouin Foundation, Universite Libre de Bruxelles Belgium 2020-04-20 2020-12-30 NCT04371250, SRB2020_158 Phase Not Applicable Not yet recruiting 1 8 Months 600 Simone Marchini, MD 2020-05-05
COVID-HO: Changes in Cardiac and Pulmonary Hemodynamics as Predictor of Outcome in Hospitalized COVID-19 Patients Coronavirus disease 19 infection endotracheal intubation and ventilation alone, non-invasive ventilation alone Universiteit Hasselt Belgium 2020-04-01 2020-12-01 COVID-HO, COVID-HO, NCT04371679 Phase Not Applicable Recruiting 1 8 Months 40 Lieven Herbots, Lieven Herbots, MD, PhD 2020-05-05
STC-19: Covid-19 Pandemic Triage Score Coronavirus disease 19 infection STC-19 score test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier de La Rochelle Numa Health International France 2020-03-01 2020-04-30 2020/P04/288, NCT04371471, STC-19 Phase Not Applicable No longer recruiting 1 2 Months 50 David Chalvet, MD, Jean-Claude Lapraz, MD, Kamyar M. Hedayat, MD, Serge Bénéteaud, MD 2020-05-06
EXPOCOVIA: Prevalence of COVID-19 Infection Among HCW in a French University Hospital Coronavirus disease 19 infection reverse transcription polymerase chain reaction (RT-PCR) alone, serological testing alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Regional Universitaire de Lille Fondation Santé Roquette France 2020-04-30 2020-09-30 2020-A00951-38, 2020_35, EXPOCOVIA, NCT04371692 Phase Not Applicable Not yet recruiting 1 5 Months 100 Annie SOBASZEK, MD, Annie SOBASZEK, MD,PhD 2020-05-05
MSCs in COVID-19 ARDS Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure Standard of care alone, remestemcel-L alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mount Sinai Medical Center Mesoblast Ltd US 2020-04-30 2022-04-30 GCO 08-1078-0014, NCT04371393 Phase 3 Clinical Recruiting 0 24 Months 300 Abhijit Duggal, Alex Iribarne, MD, Annetine C Gelijns, PhD, Bradley Leshnower, MD, Denise Kosty-Sweeney, Edward Lozano, Eustace Fernandes, MD, Hunter McDaniel, Jeffrey Sturek, MD, Jonathan Golob, MD, Kathleen Lane, Keren Osman, MD, Manal Al-Suqi, Mary Beth Marks, Michael Bowdish, MD, Michael Mack, MD, Mission Hospital, P. Eugene Parrino, MD, Peter Hou, MD, Peter Smith, MD, Sharon Eichman, Sunjay Kaushal, MD 2020-05-06
Changes in Preference for Surgery of Patients Signed up for Arthroscopic Procedures Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Region Zealand Denmark 2020-04-17 2020-04-24 ARTHROCANCELLATIONSUH2020, NCT04370678 Phase Not Applicable Completed 1 79 Jesper S Nielsen, MD 2020-05-05
A trial to evaluate the effect of plasma therapy for the prevention and treatment of coronavirus infection Coronavirus disease 19 infection plasma therapy alone Columbia University Amazon.com Inc Phase 3 Clinical Status not specified 0 450 2020-05-04
COHIVE: Coronavirus (COVID-19) Outcomes in HIV Evaluation in Resource Limited Settings Coronavirus disease 19 infection, HIV infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Centre in HIV Epidemiology and Clinical Research The University of Liverpool, UNITAID, University of Montpellier, University of Witwatersrand UK, South Africa, Switzerland, France, Australia 2020-05-15 2021-12-31 2020-04-COHIVE, COHIVE, NCT04371835 Phase Not Applicable Not yet recruiting 5 19 Months 1500 Alexandra Calmy, MD, PhD, Emmanuelle Papot, MD, Eric Delaporte, MD, PhD, Francois WD Venter, MD, Joana Woods, MD, Maria E Arriaga, PhD, Mark Polizzotto, MD, PhD, Saye Khoo, MD, PhD 2020-05-05
ACCORD 2: A Phase II Study for the Treatment of COVID 19 in Hospitalized Patients Coronavirus disease 19 infection Variable regimens including MEDI-3506 , acalabrutinib , bemcentinib , zilucoplan Axl tyrosine kinase receptor inhibitor, Btk tyrosine kinase inhibitor, Complement C5 factor inhibitor, Interleukin 33 ligand inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Southampton NHS Foundation Trust UK 2020-04-28 2020-001736-95, ACCORD 2, MasterACCORD-2-001subACCORD-2-002 Phase 2 Clinical Recruiting 1 825 Emma Perry 2020-05-06
London Ambulance Service Experience of COVID-19 Coronavirus disease 19 infection London Ambulance Service NHS Trust London School of Hygiene and Tropical Medicine UK 2020-04-09 2021-04-08 LAS-INT-2020-01, NCT04372069 Phase Not Applicable No longer recruiting 1 12 Months 40 Rachael Fothergill, PhD 2020-05-05
QT-Logs: Artificial Intelligence for QT Interval Analysis of ECG From Smartwatches in Patient Receiving Treatment for Covid-19 Coronavirus disease 19 infection artificial intelligence QT measurement alone, smartwatch ECG collection alone, azithromycin plus hydroxychloroquine Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux De Marseille France 2020-04-17 2020-05-11 CIL 2020-52, NCT04371744, QT-Logs Phase Not Applicable Recruiting 1 100 Jean Claude Deharo, MD 2020-05-06
HYdILIC: Hydroxychloroquine or Diltiazem-Niclosamide for the Treatment of COVID-19 Coronavirus disease 19 infection antibiotic therapy alone, oxygen therapy alone, standard of care alone, steroid therapy alone, Variable regimens including diltiazem , hydroxychloroquine , niclosamide , paracetamol Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Regional Universitaire de Lille University of Lille Nord de France France 2020-05-31 2023-05-31 2020-002188-72, 2020_40, HYdILIC, NCT04372082 Phase 3 Clinical Not yet recruiting 1 36 Months 480 Karine Faure, MD,PhD 2020-05-05
AMBU-COVID: Proactive Care of Ambulatory COVID-19 Patients: Open-labeled, Randomized Trial Coronavirus disease 19 infection azithromycin alone, teleconsultation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire D Amiens France 2020-04-29 2020-07-31 AMBU-COVID, NCT04371107, PI2020_843_0039 Phase 3 Clinical Not yet recruiting 1 3 Months 64 Jean-Philippe Lanoix, Jean-Philippe Lanoix, Pr 2020-05-05
Severity Score For COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Policlinico Universitario Agostino Gemelli Italy 2020-04-29 2020-05-27 3112, NCT04372199 Phase Not Applicable Recruiting 1 248 Massimo Montalto, Massimo Montalto, Professor 2020-05-05
Investigating the efficacy and safety of Hydroxychloroquine nasal spray in controlling the symptoms of patients with COVID-19 Coronavirus disease 19 infection Hydroxychloroquine nasal spray alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Baqiyatallah University of Medical Sciences Iran 2020-05-01 IR.BMSU.REC.1399.091, IRCT20080901001165N51 Phase 3 Clinical Recruiting 1 80 Nematollah Jonaidi, Parisa Kianpour, Yunes Panahi 2020-05-05
Effect of Deferiprone on the improvement of symptoms of Coronavirus 2019 (COVID-19) Coronavirus disease 19 infection deferiprone alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sanandaj University of Medical Sciences Iran 2020-05-04 IR.MUK.REC.1399.012, IRCT20180114038350N3 Phase 3 Clinical Recruiting 1 80 Karim Naseri, Khaled Rahmani 2020-05-05
CO VOR IT: COVID-19: aaddition of azithromycin to chloroquine treatment Coronavirus disease 19 infection azithromycin alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Erasmus University Medical Center Rotterdam Netherlands 2020-04-21 2020-001527-14, CO VOR IT Phase 4 Clinical Recruiting 0 60 J.G.J.V. Aerts 2020-05-06
CHAMPS: COVID-19 CHAMPS Study of Healthcare, First Responder and Service Workers Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Villanova University US 2020-04-27 2040-04-27 CHAMPS, IRB FY2020-215, NCT04370821 Phase Not Applicable Not yet recruiting 0 240 Months 20000 Donna Havens, PhD,RN,FAAN, Janell Mensinger, PhD,FAED, Peter G. Kaufmann, PhD, Sandra Schultz 2020-05-05
DYNAMIC: Doxycycline Ambulatoire COVID-19 Coronavirus disease 19 infection GRANUDOXY alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) CHU De Nantes France 2020-05-01 2020-12-01 DYNAMIC, NCT04371952, RC20_0191 Phase 3 Clinical Not yet recruiting 6 7 Months 330 Amir KHAMMARI, Amir Khammari, Anne DOMPMARTIN-BLANCHERE, Brigitte DRENO, Brigitte DRENO, PUPH, Eve MAUBEC, Fabrice BONNET, Lionel PIROTH, Marie-Thérèse Leccia 2020-05-04
TCM Intervention study for novel coronavirus pneumonia (COVID-19) patient during home/designate-unit isolation based on community prevention and control Coronavirus disease 19 infection, Viral pneumonia TCM Intervention alone Guang'Anmen Hospital China Academy of Chinese Medical Sciences, TCM China Academy of Traditional Chinese Medicine Institute of Medicine China 2020-02-03 2020-05-01 ChiCTR2000032478, ChiMCTR2000003256 Phase Not Applicable Recruiting 5 2 Months 3000 Liu Jia 2020-05-06
BCG-DENMARK-COVID: Using BCG Vaccine to Protect Health Care Workers in the COVID-19 Pandemic Coronavirus disease 19 infection BCG vaccine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bandim Health Project AJ Vaccines A/S, University of Southern Denmark Denmark 2020-05-31 2021-01-31 2020-001888-90, 20201504, BCG-DENMARK-COVID, BCG-DENMARK-COVID, NCT04373291 Phase 3 Clinical Not yet recruiting 1 8 Months 1500 Anne Marie Rosendahl Madsen, MD, Christine Stabell Benn, Professor, Clinical Institute, OPEN, Frederik Schaltz-Buchholzer, MD 2020-05-06
Experimental use of tocilizumab in COVID-19 related pneumonia Coronavirus disease 19 infection, Viral pneumonia standard of care alone, tocilizumab (intravenous), Roche/Chugai alone IL-6 receptor antagonist, IL-6 receptor modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Clinique Inter-universitaire Ambroise Paré F Hoffmann-La Roche AG Belgium 2020-04-21 2020-001770-30, 2020COVID-19TCZ Phase 2 Clinical Recruiting 1 60 dr Camelia Rossi 2020-05-06
RECOP: Emergency Management in a Dedicated Respiratory Unit of Patients With a Possible COVID Infection (Unit 'COVID Possible') Coronavirus disease 19 infection, Dyspnea Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire de Toulouse France 2020-03-13 2021-03-31 NCT04371328, RC31/20/0094, RECOP Phase Not Applicable Recruiting 1 12 Months 2000 Frédéric Balen, MD, Paul-Henri Auboiroux, MD 2020-05-04
Efficacy and Safety of Dipeptidyl Peptidase-4 Inhibitors in Diabetic Patients With Established COVID-19 Coronavirus disease 19 infection, Non-insulin dependent diabetes insulin plus linagliptin Dipeptidyl peptidase IV inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rabin Medical Center Israel 2020-05-15 2021-09-30 0303-20-RMC, NCT04371978 Phase 3 Clinical Not yet recruiting 2 16 Months 100 Alon Grossman, MD, Ran Abuhasira, Ran Abuhasira, MD 2020-05-06
Efficacy of Sn-protoporphyrin IX (SnPPIX) and Sulfonated Tetranaphthyl Porphyrin Against Covid-19 Coronavirus disease 19 infection, Viral pneumonia Sn-protoporphyrin IX alone, sulfonated tetra-anthracenyl porphyrin alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kafrelsheikh University Egypt 2020-05-31 2020-08-31 NCT04371822, PROPOSED BY MAHMOUD ELKAZZ Phase 1 Clinical Not yet recruiting 1 3 Months 56 M.Sc. Mahmoud Elkazzaz, M.Sc.Biochemistry, M.Sc.Mahmoud Elkazzaz, M.Sc.Biochemistry, Mahmoud ELkazzaz 2020-05-04
Randomized, Double-Blind, Controlled Trial of Hydroxychloroquine as Post-Exposure Prophylaxis Against COVID-19 Infection Coronavirus disease 19 infection hydroxychloroquine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sanford Health 2020-04-30 2023-04-20 NCT04372017, SH HCQ Phase 3 Clinical Not yet recruiting 0 35 Months 1739 Christie Ellison, BSN, Susan Hoover, MD 2020-05-04
BREATH: Vitamin D Polymorphisms and Severity of COVID-19 Infection Coronavirus disease 19 infection, Vitamin D deficiency Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidade de Lisboa Cardiovascular Centre of Universidade de Lisboa (CCUL), Cardiovascular Centre of Universidade de Lisboa (CCUL), Center for Health Technology and Services Research, Centro Hospitalar Sao Joao, HeartGenetics, Genetics & Biotechnology, S.A., Hospital de Santa Maria, Instituto Gulbenkian de Ciencia (IGC), Nova Medical School Portugal 2020-04-30 2021-03-31 BREATH, COVID19-BREATH, NCT04370808 Phase Not Applicable Not yet recruiting 2 11 Months 500 Ana Freitas, PhD, Ana Miranda, MD, Conceição Calhau, PhD, Fausto J Pinto, PhD, Fausto Pinto, PhD, Fátima Casaca, BSc, Helena Proença, MD, Melo Cristino, PhD, Tiago Guimarães, PhD 2020-05-06
Investigating the efficacy and safety of Azithromycin inhaled spray in controlling the symptoms of patients with COVID-19 Coronavirus disease 19 infection Azithromycin inhaled spray alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Baqiyatallah University of Medical Sciences Iran 2020-05-01 IR.BMSU.REC.1399.092, IRCT20080901001165N50 Phase 3 Clinical Recruiting 1 80 Morteza Izadi, Parisa Kianpour, Yunes Panahi 2020-05-05
A real-time, smartphone-based data collection study in order to uncover scientifically significant trends about the current coronavirus pandemic Coronavirus disease 19 infection smartphone-based data collection alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) American Lung Association, Northwestern University, University of California San Francisco Phase Not Applicable Recruiting 0 2020-05-04
PROVIDE: Hydroxychloroquine to Prevent COVID-19 Disease Amongst Healthcare Workers Coronavirus disease 19 infection hydroxychloroquine sulfate alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) St Josephs Healthcare Hamilton Canada 2020-05-01 2020-08-30 3190, NCT04371523, PROVIDE Phase 3 Clinical Not yet recruiting 1 3 Months 1100 Kimberley Lewis, Waleed Al-Hazzani, Waleed Alhazzani 2020-05-05
Study for the water extract of soybean in the treatment of patients with novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia soybean extract alone Wuhan University China 2020-03-01 ChiCTR2000030162 Phase 0 Clinical Terminated 1 2020-05-05
A phase I/IIa clinical study to assess cVLP vaccine in the treatment of patietns with COVID-19 infection Coronavirus disease 19 infection cVLP vaccine (COVID19 infection), AdaptVac alone AdaptVac EU Horizon 2020, ExpreS2ion Biotechnologies, Koebenhavns Universitet, Leiden University Medical Center, University Hospital Tubingen, Wageningen University and Research Phase 1/Phase 2 Clinical Planned 0 2020-05-04
Predicting ICU Admission And Death For COVID-19 Patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Policlinico Universitario Agostino Gemelli Italy 2020-03-01 2020-04-15 0017055/20, NCT04371562 Phase Not Applicable Completed 1 1 Month 300 2020-05-05
J-COVID: Prospective, observational study on diagnosis and treatment of COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Japanese Red Cross Medical Center Japan 2020-02-01 J-COVID, UMIN000040295 Phase Not Applicable Recruiting 1 100 Takehiro Izumo 2020-05-06
A clinical study of hydroxychloroquine versus the standard of care for the treatment in patients hospitalized with COVID-19 infection Coronavirus disease 19 infection hydroxychloroquine alone Male Food and Drug Administration US Phase Not Applicable Status not specified 0 368 2020-05-04
A pilot study to assess the clinical activity, safety and tolerability of Selective Cytopheretic Device (SCD) among patients who have ARDS prior to CRRT and/or AKI with CRRT Adult respiratory distress syndrome, Coronavirus disease 19 infection Selective Cytopheretic Device (SCD) alone Seastar Medical Inc Empiristat Inc. US 2020-04-28 SCD-005 Phase Not Applicable Recruiting 0 35 2020-05-05
Pharmacodynamics of the Nasalferon in healthy volunteers Coronavirus disease 19 infection recombinant interferon alfa 2b (Nasalferon) alone Healthy volunteers accepted, Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Center for Genetic Engineering and Biotechnology Ministerio de Salud Publica Cuba 2020-05-04 2020-06-09 IG / IAGN / VS / 2001, RPCEC00000308 Phase 1 Clinical Not yet recruiting 1 1 Month 30 Carlos Alberto GonzAlez Delgado, Hugo Nodarse Cuni 2020-05-05
Study for construction and assessment of early warning score of the clinical risk of novel coronavirus (COVID-19) infected patients Coronavirus disease 19 infection West China Hospital Science & Technology Department of Sichuan Province China 2020-01-01 2020-12-31 2020YFS0009, ChiCTR2000029907 Phase 0 Clinical Not yet recruiting 1 12 Months 1000 Yao, Rong 2020-05-05
Construction and Analysis of Prognostic Predictive Model of Novel Coronavirus Pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Zhangnan Hospital Hubei Clinical Research Center China 2020-02-01 2021-05-01 ChiCTR2000029953 Phase Not Applicable Not yet recruiting 1 15 Months 400 Xianlong Zhou, Yan Zhao 2020-05-05
HOPE study: Evaluation of the effect and safety of HeberFERON versus Heberon alfa in patients infected with the SARS-CoV-2 coronavirus (COVID-19) Coronavirus disease 19 infection HeberFERON alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Center for Genetic Engineering and Biotechnology Ministerio de Salud Publica Cuba 2020-04-10 2020-07-30 HOPE study, IG / IAG / CV / 2001, RPCEC00000307 Phase 2 Clinical Recruiting 1 3 Months 120 Idelsis Esquivel Moynelo, Irraldo Bello Rivero 2020-05-05
Triple combination therapy in patients infected with COVID-19 Coronavirus disease 19 infection, Viral pneumonia Variable regimens including hydroxychloroquine sulfate , lopinavir + ritonavir , oseltamivir Exo-alpha sialidase inhibitor, HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gunma University Hospital Japan 2020-04-01 jRCTs031190227 Phase 2 Clinical Recruiting 1 50 Nakamura Tetsuya, Tokue Yutaka 2020-05-05
Favipiravir in patients infected with COVID-19 Coronavirus disease 19 infection, Viral pneumonia favipiravir alone RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gunma University Hospital Japan 2020-03-14 jRCTs031190226 Phase 2 Clinical Recruiting 1 50 Nakamura Tetsuya, Tokue Yutaka 2020-05-05
RACCO: A multicenter, open-label, randomized, controlled trial to evaluate the efficacy and safety of inhaled ciclesonide for asymptomatic and mild patients with COVID-19 Coronavirus disease 19 infection, Viral pneumonia ciclesonide alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Japanese Ministry of Health, Labor and Welfare Japan 2020-04-03 RACCO, jRCTs031190269 Phase 2 Clinical Recruiting 1 90 Junko Terada, Sugiyama Haruhito 2020-05-05
Favipiravir for SARS-CoV-infected patients Coronavirus disease 19 infection favipiravir alone RNA polymerase inhibitor Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Japan Agency for Medical Research and Development Japan 2020-03-02 jRCTs041190120 Phase 2 Clinical Recruiting 1 86 Doi Yohei, Kondo Masashi 2020-05-05
CHARTER: COVID-19: can nebulized heparin reduce time to extubation in SARS-CoV-2 patients requiring mechanical ventilation Coronavirus disease 19 infection heparin alone, invasive mechanical ventilation alone, standard care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) St Vincents Hospital (Melbourne) Ltd Victorian State Government Australia 2020-05-21 2021-07-25 ACTRN12620000517976p, CHARTER Phase 3 Clinical Not yet recruiting 3 14 Months 172 Dr Barry Dixon 2020-05-05
SARS-CoV2 in children presenting to hospital: a repeating point prevalence study during the COVID-19 pandemic in South East Queensland Coronavirus disease 19 infection PCR alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) Gold Coast Hospital Griffith University Australia 2020-04-29 2020-09-18 ACTRN12620000512921, HREC/2020/QGC/63198 Phase Not Applicable Not yet recruiting 1 4 Months 400 A/Prof Shane George 2020-05-05
ARDS Caused by COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Clinic of Barcelona Ubikare company Spain 2020-03-12 2020-12-31 COVID-19 ARDS, NCT04368975 Phase Not Applicable Recruiting 1 9 Months 500 Carlos Ferrando, Carlos Ferrando, PhD, Sara Darriba, PhD 2020-05-05
Clinical Application of Methylene Blue for Treatment of Covid-19 Patients Coronavirus disease 19 infection MCN (methylene blue, vitamin C, N-acetyl cysteine) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mashhad University of Medical Sciences Iran 2020-04-19 2020-09-21 IR.MUMS.REC.1399.122, NCT04370288 Phase 1 Clinical Recruiting 1 5 Months 20 Ahmad Bagheri Moghaddam, M.D, Amir Yarahmadi, Ph.D, Daryoush Hamidi Alamdari, Ph.D 2020-05-05
Efficacy and Safety Study of IV Ravulizumab in Patients With COVID-19 Severe Pneumonia Acute lung injury, Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia Best Supportive Care alone, ravulizumab alone Complement C5 factor inhibitor, IgG receptor FcRn large subunit p51 modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Alexion Pharmaceuticals Inc 2020-05-31 2021-02-28 ALXN1210-COV-305, NCT04369469 Phase 3 Clinical Not yet recruiting 0 9 Months 270 Alexion Pharmaceuticals, Inc. 2020-05-04
Repeated Measures Trial of Temporary Automated Manual Ventilation Versus Noninvasive Oxygenation or Conventional Vent Coronavirus disease 19 infection, Lung infection, Respiratory failure Mechanical ventilation alone, automated BVM compressor device, Spiro LLC/10x beta alone, rocuronium alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Massachusetts General Hospital 2020-05-31 2020-11-30 2020P001051, NCT04369274 Phase 2 Clinical Not yet recruiting 0 6 Months 30 Blair Parry, CCRC, Keith A Marill, MD 2020-05-05
BATTLE: COVID-19: BCG as Therapeutic Vaccine, Transmission Limitation, and Immunoglobulin Enhancement Coronavirus disease 19 infection BCG vaccine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidade Estadual de Campina Botucatu Medical School, Conselho Nacional de Desenvolvimento Cientifico e Tecnologico - CNPq, Faculdade de Medicina de Ribeirão Preto, Federal University of Sao Paulo, Instituto de Infectologia Emílio Ribas, Paulinia Municipal Hospital, Pontificia Universidade Catolica de Campinas, State Hospital Dr. Leandro Franceschini Brazil 2020-06-30 2022-05-31 BATTLE, COVID-19 BATTLE TRIAL, NCT04369794 Phase 4 Clinical Not yet recruiting 1 23 Months 1000 Bethania F Nascimento, BSN, Leonardo O Reis, MD, PhD 2020-05-04
Anxiety And Depression During COVID-19 In India Anxiety disorder, Coronavirus disease 19 infection, Depression Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Max Healthcare Institute Ltd, India India 2020-04-24 2021-02-24 COVID-19/MHC/PSYCH/20-10, NCT04369300 Phase Not Applicable Not yet recruiting 1 10 Months 1000 2020-05-04
MATCH: Multi-site Adaptive Trials Using Hydroxycholoroquine for COVID-19 Coronavirus disease 19 infection famotidine plus hydroxychloroquine Histamine H2 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Northwell Health Inc US 2020-04-07 2021-04-07 20-0268, MATCH, NCT04370262 Phase 3 Clinical Recruiting 0 12 Months 1170 Amanda Tice, RN, Asha Mellor, CCRC, Christina Brennan, MD, John Boockvar, MD, Joseph Conigliaro, MD, Julie DiGregorio, CCRP, Negin Hajizadeh, MD, Neubert Philippe, MD, Patricia Nadraus, RN, Richard Dima, MD, Tamika Wong, MPH 2020-05-06
Trans Thoracic Manipulation of Ventilation/Perfusion: the V/Q Vest Coronavirus disease 19 infection, Hypoxia, Respiratory distress syndrome, Respiratory failure V/Q Vest alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Emory University Georgia Institute for Clinical Research, Georgia Institute of Technology US 2020-05-31 2021-03-31 NCT04369599, STUDY00000402 Phase Not Applicable Not yet recruiting 0 10 Months 24 Maxwell Weinmann, MD 2020-05-04
Curie-O-SA: COVID-19 Study of the Serological Response Against the Severe Acute Respiratory Syndrome (SARS) Coronavirus 2 (CoV-2) Virus in 2 Types of Employees, Hospital and Non-hospital, at Institute Curie Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institut Curie France 2020-04-28 2021-01-28 Curie-O-SA, IC 2020-07, NCT04369066 Phase Not Applicable Recruiting 1 9 Months 2500 Isabelle Turbiez, Olivier Lantz, MD, Pierre Fumoleau, PhD 2020-05-04
XPro-1595 for the Treatment of Pulmonary Complications From COVID-19 Coronavirus disease 19 infection, Lung disease INB-03 alone, standard of care alone TNF alpha ligand inhibitor Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) INmune Bio Inc 2020-06-30 2021-01-31 NCT04370236, XPRO1595-COVID-19 Phase 2 Clinical Not yet recruiting 0 7 Months 150 Christopher Barnum, PhD 2020-05-05
COVID-19.KDIR.01: Long-term Analysis and Evaluation of morphologic and clinical Parameters in COVID-19 Patients: prospective development of a practical risk score Coronavirus disease 19 infection, Viral pneumonia CT scan alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Stuttgart Cancer Center Germany 2020-04-17 COVID-19.KDIR.01, DRKS00021537, F-2020-047, U1111-1251-0942 Phase Not Applicable Recruiting 1 150 Götz Martin Richter 2020-05-04
SARS-CoV-2 in tears in patients with COVID-19 Coronavirus disease 19 infection, Ocular disease RT-PCR assay alone, funduscopy alone, slit-lamp examination alone Universitatsklinikum Schleswig-Holstein Campus Kiel Germany 2020-04-29 D 469/20, DRKS00021416 Phase Not Applicable Recruiting 1 30 Mr. Prof. Dr. med. Johann Baptist Roider, Ms. Dr. med. Kristin Hosel 2020-05-04
ATHLOS: Telerehabilitation in Patients With COVID-19 After Hospitalization Coronavirus disease 19 infection aerobic exercise alone, breathing exercise alone, resistive training exercise alone, telerehabilitation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Clinical Exercise Physiology and Rehabilitation Reasearch Laboratory University of Athens, University of Ioannina, University of Thessaly Greece 2020-04-30 2021-03-31 1, ATHLOS, NCT04368845 Phase Not Applicable Not yet recruiting 1 11 Months 100 ELENI KAPRELI, PhD, PT, ELENI KORTIANOU, PhD, PT, Eleni Kortianou 2020-05-04
Management of Covid-19 Patients During Home Isolation Coronavirus disease 19 infection oxygen alone, physical therapy alone Young Adults (18-44 yrs) Cairo University Egypt 2020-03-15 2020-05-20 2318087, NCT04368923 Phase 2 Clinical No longer recruiting 1 2 Months 60 Mahmoud Sedky 2020-05-04
COVID-OZO: Ozone Auto-hemotherapy for COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia ozone auto-hemotherapy alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) L'Institut d Investigacio Biomedica de Girona Hospital Nuestra Señora del Rosario, Sociedad Española de Ozonoterapia Spain 2020-05-04 2020-12-25 COVID-19 NETWORKING GROUP, COVID-OZO, NCT04370223 Phase 3 Clinical Not yet recruiting 9 7 Months 208 Alberto Hernández, MD, PhD, Antònia Flor, MD, Eduardo Tamayo, MD, PhD, Isabel Guitart, MD, Javier Ripolles, MD, PhD, Marc Vives, MD, Marc Vives, MD, PhD, Miguel Angel Garcia, MD, Noelia Zurera Plaza, MD 2020-05-06
JoCORE: Acute Cardiovascular Events Triggered by COVID-19-Related Stress Acute stress disorder, Cardiovascular disease, Coronavirus disease 19 infection, Myocardial infarction, Shock, Sudden cardiac death, Ventricular tachycardia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Jordan Collaborating Cardiology Group Jordan 2020-05-03 2020-08-30 JCCG.JOCORE.4.4040, JoCORE, NCT04368637 Phase Not Applicable Recruiting 6 3 Months 50 Ayadeh Madanat, MD, Ayman Hammoudeh, MD, FACC, Ayman J Hammoudeh, MD, FACC, Ayman J. Hammoudeh, MD, FACC, Eyadeh Madanat, MD, Hadi Abu Hantash, MD, FACC, Hadi Abu hantash, MD, FACC, Imad Alhaddad, MD, Mahmoud Fakhri, MD, Mahmoud Izraiq Mahmoud Izraiq, MD, Walaa Abu Moghli, PharmD, Zaid Khouri, MD, Zeina Abu Orabi, MD 2020-05-06
VIRUS: Construction of a Composite Clinical-echo Score Predictive of a Risk of Short-term Aggravation of Respiratory Impairment in Patients Suspected of Covid-19 Coronavirus disease 19 infection, Respiratory failure clinical-echo score prediction alone, pleuro-pulmonary ultrasound alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) CHU De Nantes WINFOCUS-France France 2020-04-09 2020-06-30 NCT04370249, RC20_0164, VIRUS Phase Not Applicable Recruiting 1 2 Months 400 Philippe LE CONTE, Philippe LE CONTE, MD-PHD, Philippe PES, MD 2020-05-04
CONFIDODO: Sleep Quality During COVID-19 Containment in Children Whether or Not Usually Followed in Child Psychiatry Anxiety disorder, Coronavirus disease 19 infection, Depression, Sleep disorder routine psychiatric care alone Healthy volunteers accepted, Children (6-12 yrs) Centre Hospitalier René-Dubos France 2020-05-31 2020-06-30 CHRD 0520, CONFIDODO, NCT04370210 Phase Not Applicable Not yet recruiting 1 1 Month 464 Erwan VION, Maryline Delattre, Véronique Da Costa 2020-05-04
Project D: Observational Study to Assess the Seroconversion Status of Health Care Workers and Suspected or Confirmed Cases of COVID-19 Patients Coronavirus disease 19 infection COVID-19 testing alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Max Healthcare Institute Ltd, India India 2020-04-22 2020-07-30 COVID-19/MHC-2/2020, NCT04368884, Project D Phase Not Applicable Recruiting 1 3 Months 1000 Samreen Siddiqui, PhD, Sujeet Jha, MRCP (U.K), Swati Waghdhare, MD 2020-05-04
Observational Study of COVID-19 Treatment Efficacy Coronavirus disease 19 infection, Respiratory distress syndrome hydroxychloroquine alone, remdesivir alone, azithromycin plus hydroxychloroquine Coronavirus non structural protein 8 modulator, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) OSF Healthcare System US 2020-04-14 2021-04-14 1589936, NCT04369989 Phase Not Applicable Recruiting 0 12 Months 1000 David Hall 2020-05-04
TEACH: Treating COVID-19 With Hydroxychloroquine Coronavirus disease 19 infection hydroxychloroquine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) NYU Langone Health SUNY Downstate Medical Center US 2020-04-15 2020-06-30 20-00463, NCT04369742, TEACH Phase 2 Clinical Recruiting 0 2 Months 626 Jack A. DeHovitz, MD, MPH, MHCDS, FACP, Mark Mulligan, MD, Mark Mulligan, MD, FIDSA, Robert Ulrich, MD 2020-05-04
COVERSCAN: Mapping Organ Health Following COVID-19 Disease Due to SARS-CoV-2 Infection Coronavirus disease 19 infection MRI alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Perspectum Diagnostics Ltd UK 2020-04-21 2023-05-31 20/SC/0185, COVERSCAN, NCT04369807 Phase Not Applicable Recruiting 2 37 Months 507 Mary Norris Xu, BSc, RN, Rajarshi Banerjee, MSc, DPhil, Sandeep Kapur, BSc, MBBS 2020-05-04
Evaluation of the Safety and Immunogenicity of a SARS-CoV-2 rS (COVID-19) Nanoparticle Vaccine With/Without Matrix-M Adjuvant Coronavirus disease 19 infection SARS-CoV recombinant vaccine (nanoparticle), Novavax alone, Matrix M plus SARS-CoV recombinant vaccine (nanoparticle), Novavax Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Novavax Inc Australia 2020-05-15 2021-07-31 2019NCOV-101, NCT04368988 Phase 1/Phase 2 Clinical Not yet recruiting 2 14 Months 131 Biljana Georgievska 2020-05-04
Stroke-Covid19: Covid-19 Epidemic on Acute Stroke Management Coronavirus disease 19 infection, Stroke Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopitaux Universitaires de Strasbourg France 2020-03-03 2020-04-30 7826, NCT04370197, Stroke-Covid19 Phase Not Applicable Recruiting 1 1 Month 300 Raoul POP, MD, Rémy BEAUJEUX, MD, PhD, Saïd CHAYER, PhD, HDR 2020-05-04
PROTECT: Improving prenatal care during confinement Coronavirus disease 19 infection, Parturition remote consultation alone Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Hospital, Nancy, France 2020-05-01 2021-09-30 2020-A01023-36, NCT04368832, PROTECT Phase Not Applicable Not yet recruiting 0 17 Months 108 Gaëlle Ambroise, Nadine JUGE 2020-05-04
Study to Describe the Safety, Tolerability, Immunogenicity, and Potential Efficacy of RNA Vaccine Candidates Against COVID-19 in Healthy Adults Coronavirus disease 19 infection Variable regimens including BNT-162a1 , BNT-162b1 , BNT-162b2 , BNT-162c2 COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) BioNTech SE Pfizer Inc US 2020-04-29 2023-01-27 C4591001, NCT04368728 Phase 1/Phase 2 Clinical Recruiting 0 32 Months 7600 Pfizer CT.gov Call Center 2020-05-06
Hydroxychloroquine Chemoprophylaxis for COVID-19 Infection in High-risk Healthcare Workers: Randomized, Controlled Trial Coronavirus disease 19 infection hydroxychloroquine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) SERVICES INSTITUTE OF MEDICAL SCIENCES Pakistan 2020-04-30 2020-10-31 16082019, NCT04370015 Phase 2 Clinical Not yet recruiting 1 6 Months 374 Khadija I Khawaja, FCPS, Saira Burney, FRCP (Edin) 2020-05-04
CORRECT: COvid (Covid-19) Registry REChts der Isar intensive care Trial Adult respiratory distress syndrome, Coronavirus disease 19 infection extracorporeal organ support alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Technical University of Munich Germany 2020-03-30 178/20S, CORRECT, DRKS00021612 Phase Not Applicable Recruiting 1 500 Sebastian Rasch 2020-05-04
TeleCoviDiab: Management of Diabetic Patients With Telemedicine in the Context of the Covid-19 Epidemic Coronavirus disease 19 infection, Insulin dependent diabetes, Non-insulin dependent diabetes teleconsultation alone, telemedicine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital of Strasbourg France 2020-05-31 2020-12-31 7775, NCT04370171, TeleCoviDiab Phase Not Applicable Not yet recruiting 1 7 Months 200 Eric DEMONSANT 2020-05-06
SeCo: Screening for SARS-CoV-2-Infections and Monitoring of Serological Responses to SARS-CoV-2 in Healthcare Workers Coronavirus disease 19 infection Anti-SARS-CoV2 S protein IgG ELISA alone, SARS-CoV-2 PCR alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Medicine Greifswald EUROIMMUN GmbH, Friedrich Loeffler Institute Germany 2020-04-27 2025-05-31 BB 068/20, NCT04370119, SeCo Phase Not Applicable Recruiting 2 61 Months 4000 Andreas Greinacher, Prof.Dr., Christine Rutscher, Dipl.-Med., Henry Völzke, Prof.Dr., Karsten Becker, Prof.Dr., Lena Ulm, Dr., Marek Zygmunt, Prof.Dr., Martin Beer, Prof.Dr., Martin Groschup, Prof.Dr., Matthias Nauck, Prof.Dr., Mladen V. Tzvetkov, Prof.Dr., Nicole Endlich, Prof.Dr., Nils-Olaf Hübner, Prof.Dr., Thomas C. Mettenleiter, Prof.Dr., Wolfgang Schlumberger, Dr. 2020-05-04
PAN-COVID: A global registry of women affected by COVID-19 in pregnancy and their babies, to guide treatment and prevention Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Imperial College London United Kingdom Research & Innovation Israel, India, Japan, Lebanon, Mexico, Argentina, Canada, Greece, UK, Romania, US, Belgium, Indonesia, Germany, Russian Federation, Czech Republic, Austria, Guatemala, Tunisia, Brazil, Netherlands, South Africa, Latvia, Bosnia and Herzegovina, Colombia, Nigeria, Spain, Malta, Peru, Thailand, Uganda, Italy, United Arab Emirates, Hungary, Australia, Ireland, Qatar, Portugal, Ecuador, Chile, Estonia, Egypt 2020-01-01 2021-09-30 20QC5917, IRAS 282655, ISRCTN68026880, PAN-COVID Phase Not Applicable Recruiting 42 21 Months 1000 Dr Mullins 2020-05-04
POCUSars-CoV-2: Accuracy of Lung Ultrasound in the Diagnosis of COVID-19 Pneumonia Coronavirus disease 19 infection, Respiratory disease, Viral pneumonia lung ultrasound alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Latisana Hospital Italy 2020-04-23 2020-05-31 CEUR-2020-OS-086, NCT04370275, POCUSars-CoV-2 Phase Not Applicable Recruiting 1 1 Month 235 Carmine C Di Gioia, MD, Daniele Orso, MD, Roberto Copetti, MD, Director 2020-05-04
In-vitro Diagnostic Test to Predict COVID-19 Mortality and Disease Severity Coronavirus disease 19 infection Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Applied Biology Inc Hospital Universitario Ramon y Cajal Spain 2020-05-01 2020-12-01 AB-IVD-COV-001, NCT04368897 Phase Not Applicable Recruiting 1 7 Months 200 Andy Goren, MD, Carlos Wambier, MD, Sabina Herrera, MD 2020-05-06
Hungarian CoronaVirus Disease-19 Epidemiological Research Coronavirus disease 19 infection Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Semmelweis University Heart and Vascular Center Semmelweis University, University Of Pécs, University of Debrecen, University of Szeged Hungary 2020-05-01 2021-08-01 H-UNCOVER, NCT04370067 Phase Not Applicable Not yet recruiting 4 15 Months 11200 Andor Sebestyén, MD,PhD, Annamaria Kosztin, MD,PhD, Béla Merkely, PhD,DSc, Csaba Lengyel, MD,PhD, Ervin László Berényi, MD,PhD 2020-05-04
Radiographic Findings and Their Temporal Changes in COVID-19 Positive Changes Patients: a Prospective Study Coronavirus disease 19 infection real time reverse transcriptase polymerase chain reaction(rRT-PCR) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Max Healthcare Institute Ltd, India India 2020-04-28 2021-05-30 COVID-19/RFTC/MHC/2020, NCT04368871 Phase Not Applicable Not yet recruiting 1 13 Months 200 Bharat Aggarwal, Rajesh Saxena 2020-05-05
GROCO: Obstetric and Perinatal Outcomes of Women With COVID-19 Coronavirus disease 19 infection Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux De Marseille France 2020-04-23 2021-04-22 2020-18, GROCO, ID RCB, NCT04369859 Phase Not Applicable Recruiting 1 12 Months 1300 Florence BRETELLE, PU-PH, Jean-Olivier ARNAUD, Director 2020-05-05
C5-COV: C5a Receptor Expression - COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux De Marseille Innate Pharma SA France 2020-03-31 2020-11-30 2020-14, C5-COV, IDRCB, NCT04369820 Phase Not Applicable Recruiting 1 8 Months 100 Emilie EGP GARRIDO-PRADALIE, Julien CARVELLI, Julien JC CARVELLI, MD, Kahéna AMICHI, Kahéna KA AMICHI, Laurent PAPAZIAN, Lionel VELLY, Marc GAINNIER, Nicolas SCHLEINITZ, Pierre-Yves CORDIER 2020-05-05
C19Survey: The Psychological, Social, and Economic Impacts of COVID-19 Coronavirus disease 19 infection, Psychiatric disorder online survey alone Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Ottawa CHEO Research Institute, Centre for Addiction and Mental Health, Ciusss du Nord-De-L'île-De-Montréal, Hopital Du Sacre-Coeur De Montreal, Johns Hopkins University, McGill University, Ottawa Heart Institute Research Corp, Ottawa Hospital Research Institute, Southlake Regional Health Centre, Sunnybrook Health Sciences Centre, The Royal's Institute of Mental Health Research, Universite De Montreal Canada 2020-04-03 2021-04-03 2131, C19Survey, NCT04369690 Phase Not Applicable Recruiting 10 12 Months 1000 Addo Boafo, MD, Alexander Daros, PhD, CPsych, Cynda Rushton, RN, PhD, Denis Lafortune, PhD, Edward Spilg, FRCP, MSc, Elizaveta Solomonova, PhD, Janet Jeffrey, RN, PhD, Jennifer Phillips, PhD, Jodi Edwards, PhD, Kaitlyn Lopes, Lena Quilty, PhD, CPsych, Mamta Gautam, FRCP MBA, Marie-Hélène Pennestri, PhD, Mysa Saad, MSc, Raj Bhatla, MD FRCPC, Richard H Swartz, MD, PhD, Richard Swartz, MD, PhD, Roger Godbout, PhD, Rébecca Robillard, Rébecca Robillard, PhD, Samuel Paul Louis Veissière, PhD, Tetyana Kendzerska, MD PhD, Tetyana Kendzerska, MD, PhD, Wendy Gifford, RN, PhD, Zachary Kaminsky, PhD 2020-05-04
DigitalDoc: The Digital Doc in the Emergency Department: The solution for patient care in the Covid-19 pandemic? Coronavirus disease 19 infection telemedicine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Maxima Medical Center Netherlands 2020-04-08 2020-09-01 DigitalDoc, NL8522 Phase Not Applicable Recruiting 1 4 Months 50 Bart Candel 2020-05-04
Neuroinvasion in COVID-19 Coronavirus disease 19 infection, Respiratory disease RT-PCR alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Zuyderland Medical Center, Heerlen Netherlands 2020-04-26 2020-06-26 NL8526 Phase Not Applicable Not yet recruiting 1 2 Months 10 Floris Smeets 2020-05-04
Volatile Anesthetics in COVID-19 – a pilot study Coronavirus disease 19 infection, Respiratory distress syndrome isoflurane alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitair Medisch Centrum Utrecht Netherlands 2020-04-26 2020-05-31 NL8523 Phase 2 Clinical Not yet recruiting 1 1 Month 20 Jan Dieleman 2020-05-04
Duke COVID-19 Shared Data and Specimen Repository Coronavirus disease 19 infection Duke University US 2020-05-05 2025-04-30 NCT04368234, PRO00105316 Phase Not Applicable Recruiting 0 59 Months 100000 Chris Woods, MD, Lynn Sutton 2020-05-04
COVILUS: Lung Ultrasound to Diagnose COVID-19 Coronavirus disease 19 infection, Respiratory failure lung ultrasound alone, reverse transcription polymerase chain reaction test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire D Amiens France 2020-04-28 2020-09-28 COVILUS, NCT04368338, PI2020_843_0030 Phase Not Applicable Recruiting 1 5 Months 100 Stéphane Bar, Dr, Stéphane Bar, MD 2020-05-04
SCOPe: To Study the Clinical Characteristics and Treatment Outcome of COVID-19 Patients Admitted in Hospitals of Max Healthcare Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Max Healthcare Institute Ltd, India, Max Super Speciality Hospital India 2020-04-25 2020-07-25 CTRI/2020/04/024859, NCT04367064, SCOPE/MHC/COVID-19/2020, SCOPe Phase Not Applicable Recruiting 1 3 Months 1000 Dr Ram Shankar Mishra, Rajesh Saxena, Rajesh Saxena, MBA, Ram Shankar Mishra, DNB, FRCP, Sandeep Budhiraja, MRCP, FACP 2020-05-04
ELCOVID: Electrocardiogram Analysis in COVID-19 Patients Cardiovascular disease, Coronavirus disease 19 infection blood test alone, cardiac magnetic resonance imaging alone, radiographic examination alone, transthoracic echocardiography alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Azienda Ospedaliero-Universitaria di Ferrara Italy 2020-04-14 2021-12-01 385/2020/OSS/AOUFE, ELCOVID, NCT04367129 Phase Not Applicable Recruiting 1 19 Months 1000 Matteo Bertini, MD, PhD, Michele Malagù, MD 2020-05-04
EuroECMO-COVID: European/Euro-ELSO Survey on Adult and Neonatal/Pediatric COVID-19 Patients in ECMO Cardiogenic shock, Coronavirus disease 19 infection, Lung disease, Septic shock extracorporeal membrane oxygenation alone Maastricht University Medical Center Antwerp University Hospital, Azienda Ospedaliera Citta della Salute e della Scienza di Torino, Azienda Ospedaliero-Universitaria Ospedali Riunit, Azienda Ospedaliero-Universitaria di Udine, Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia, Cardiocentro Ticino, Centre Hospitalier Universitaire Saint Pierre, Centre Hospitalier Universitaire de Liege, Centro Hospitalar Sao Joao, Charles University, Chelyabinsk Regional Clinical Hospital, City Clinical Hospital No. 67, Moscow, Russia, City Hospital No 40, City Hospital No 41, Ekaterinburg, Department of Cardiovascular Surgery, German Heart Center Munich, Erasme Hospital, Erasmus University Medical Center Rotterdam, European chapter of the Extracorporeal Life Support Organization, G Gaslini Children's Hospital, G. Pasquinucci Heart Hospital, Massa, General University Hospital, Prague, Great Ormond Street Hospital for Children NHS Foundation Trust, Guy's & St Thomas' Hospital NHS Trust, Hannover Medical School, Heart Center Leipzig GmbH, Heim Pal Children's Hospital, Henri Mondor Hospital, Herlev Hospital Region Hovedstaden, Hopital Prive La Louviere, Hopital Universitaire de la Pitie Salpetriere, Hopitaux Universitaires De Geneve, Hospices Civils De Lyon, Hospital Miguel Servet, Hospital San Gerardo, Hospital Sant Joan de Deu, Hospital Universitario Ramon y Cajal, Hospital Vall D'Hebron, Hôpital Civil Marie Curie de Charleroi, IRCCS Policlinico San Matteo, Istituto Scientifico H San Raffaele, Karolinska University Hospital, Kemerovo Regional Clinical Cardiological Center named after academician L.S. Barbarash, Klinik Hirslanden, Klinikum Kassel GmbH, Krasnodar Regional Hospital no 1, Landesklinikum Sankt Polten, Leiden University Medical Center, Medical University of Vienna, Medical University of Warsaw, Newcastle Upon Tyne Hospitals NHS Trust, Niguarda Hospital, Novosibirsk City Hospital #2, Onze-Lieve-Vrouwziekenhuis Aalst Hospital, Ospedale Maurizio Bufalini, Ospedale Papa Giovanni XXIII, Ospedale Pediatrico Bambino Gesù (IRCCS), Ospedale S. Giovanni Bosco, Ospedale San Donato, Ospedale Umberto, Ospedale dell'Angelo, Paediatric Intensive Care Glasgow, Politecnico Di Milano, Rennes University Hospital, Rijksuniversiteit te Groningen, Royal Brompton & Harefield NHS Trust, San Bortolo Hosp, San Camillo Hospital, Rome, San Giorgio Clinic, Skåne University Hospital, St. Orsola Hospital, The Mediterranean Institute for Transplantation and Advanced Specialized Therapies, Tirol Kliniken, Universitair Medisch Centrum Utrecht, Universitair Ziekenhuis Brussel, Universitair Ziekenhuis Gent, Universitaire Ziekenhuizen Leuven, Universitat Duisburg Essen, Universitatsklinikum Essen, University General Hospital of Alexandroupolis, University Hospital Basel, University Hospital Regensburg, University Hospital Tubingen, University Hospital, Aachen, University Hospital, Bordeaux, University Hospital, Montpellier, University Hospitals of Leicester - Leicester Royal Infirmary, University of Bern, University of Erlangen-Nurnberg Medical School, University of Lausanne Hospitals, University of Zurich, Universitätklinikum Düsseldorf, Universitätsklinikum Koln, Vilnius University Hospital Santariškių Klinikos Denmark, Czech Republic, France, Portugal, Spain, Russian Federation, Austria, Switzerland, Italy, Israel, Sweden, Belgium, Germany, Netherlands, Greece, Poland, Lithuania, Hungary, UK 2020-04-10 2021-04-30 EuroECMO-COVID, METC 2020-1343, NCT04366921 Phase Not Applicable Recruiting 97 12 Months 150 Aaron Blandino, Ortiz, Alain Combes, Prof., Alberto Weber, Prof. Dr., Alessandro Paradiso, Dr., Alexander Kersten, Dr., Alexander Skopets, Alexandr Turchaninov, Alexandra Shilova, Allesandro Circelli, Dr., Andrea Montalto, Dr., Andrea Moscatelli, Angelo Polito, Antioco Cappai, Dr., Antonella Degani, Antonio Loforte, Dr., Aron Frederik Popov, Prof., Bernard Stockman, Dr., Christian Napp, Dr., Christoph Krapf, Dr., Claire Westrope, Daniel De Backer, Dr., Daniil Shelukhin, Dario Candura, Dr., Dario Fina, Dr., David Schibilsky, Dr., Davide Ghitti, Dr., De Piero, Drs., Dimitri Vandeweghe, Dimitrios Soufleris, Dinis Reis Miranda, Dr., Diyar Saeed, Prof., Edgars Grins, Esther Dreier, Dr., Fabio Taccone, Prof., Felix Hennig, Dr., Finn Moeller Pedersen, Dr., Gabriel Saiydoun, Dr., Gerdy Debeuckelaere, Giacomo Cavallaro, Gianluca Agus, Dr., Gil Bolotin, Dr., Giovanni Chiarini, Dr., Giovenni Landoni, Grünenfelder Jürg, Prof. Dr., Halbe Maximillian, Dr., Harlinde Peperstraete, Ignazio Condello, Igor Komilov, Ivan Akufov, J.J. van der Heijden, Dr., Jacinta Maas, Dr., Jan Belohlavek, Prof., Jan Schmitto, Prof., Jenni Hansjoerg, Jolanda Consiglio, Jordi Riero del Brio, Dr., Judit Llevadias, Justyna Swol, Dr., Katherine Brown, Lars Broman, Dr., Leen Vercaemst, Dr., Lo Coco, Drs., Lorusso, Prof. Dr., Luis Filipe Pinto, Dr., Maged Makhoul, Dr., Malaika Mendoca, Mara Scandroglio, Marc Lagny, Marco Giani, Dr., Marco Moscarelli, Dr., Marco Piccichè, Marco Ranucci, Dr., Maria Elena De Piero, Dr., Mariusz Kowaleswsky, Dr., Mark Davidson, Martin Kneyber, Matteo Di Nardo, Matteo Pozzi, Dr., Matthias Thielman, Prof., Maximillian Malfertheiner, Dr., Michael Piagnerelli, Mirko Belliato, Dr., Nicholas Bartlett, Dr., Nikolaos Bonaros, Prof., Olivier Brissaud, Olivier Germay, Pablo Ruiz, Dr., Paolo Del Sarto, Paolof Meani, Dr., Patrick Biston, Dr., Peter Schellongowski, Dr., Philipp Hen, Dr., Phillipe Gaudard, Pierre Tissieres, Ralf Muellenbach, Prof, Reina Gianfranco, Dr., Robertas Samalavicius, Dr., Roberto Carozza, Roberto Rona, Dr., Romain Courcelle, Roman Komelyuk, Sandrelli Luca, Dr., Sandro Sponga, Dr., Sergei Minin, Simone Schafer, Dr., Susana Segura Matute, Sven Maier, Dr., Thierry Folliguet, Prof., Thomas Doebele, Torje Iuliu, Dr., Udo Boeken, Prof., Vaclav Vobruba, Verna Aquino, Veronika Maraczi, Vito Fanelli, Dr., Xavier Bechtold 2020-05-04
COVID-19 outbreak and solid organ transplantation (SOT): an international, web-based survey Coronavirus disease 19 infection, Organ transplantation Policlinico Universitario Agostino Gemelli Italy 2020-03-24 2020-04-17 COVID-19_V1, NCT04367896 Phase Not Applicable Completed 1 1819 2020-05-01
COVID PRAYER: The COVID-19 ICU PRAYER Study Coronavirus disease 19 infection remote intercessory multi-denominational prayer alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kansas City Heart Rhythm Institute US 2020-05-01 2020-08-31 COVID PRAYER, COVID PRAYER STUDY, NCT04361838 Phase Not Applicable Not yet recruiting 0 4 Months 1000 Dhanunjaya Lakkireddy, MD, Donita Atkins, RN, BSN 2020-05-01
COVID19-CHIEF: COVID-19 Infection in Patients With Hepatocellular Carcinoma Coronavirus disease 19 infection, Hepatocellular carcinoma, Viral pneumonia nasopharyngeal Covid-19 RT-PCR alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire D Amiens Central Hospital, Nancy, France, Centre Hospitalien Sud Francilien, Centre Hospitalier Intercommunal Creteil, Centre Hospitalier Regional Universitaire de Lille, Centre Hospitalier Universitaire De Nice, Centre Hospitalier Universitaire De Poitiers Etablissement D’Hospitalisation, Centre Hospitalier Universitaire de Toulouse, Hospices Civils De Lyon, Hospital Boisguillaume, Hôpital Paul Brousse, Jean Verdier Hospital, Rennes University Hospital, University Hospital, Bordeaux, University Hospital, Grenoble, University Hospital, Montpellier France 2020-04-27 2020-10-31 COVID19-CHIEF, NCT04367805, PI2020_843_0042 Phase Not Applicable Recruiting 1 6 Months 50 Aurore BARON, MD, Christine SILVAIN, Pr, Eric ASSENAT, Pr, Eric NGUYEN KHAC, Pr, Giuliana AMADDEO, MD, Jean Pierre BRONOWICKI, Pr, Jean-Frédéric BLANC, MD, Jean-Marie PERON, Pr, Julien EDELINE, MD, Mohamed BOUATTOUR, MD, Nathalie GANNE-CARRIE, Pr, Olivier GANRY, Pr, Olivier Ganry, Pr, Philippe MATHURIN, Pr, Philippe MERLE, Pr, Pierre MICHEL, Pr, Rodolphe ANTY, Pr, Thomas DECAENS, Pr, Éric VIBERT, Pr 2020-05-01
ColchiVID: Colchicine Twice Daily During 10 Days as an Option for the Treatment of Symptoms Induced by Inflammation in Patients With Mild and Severe Coronavirus Disease Coronavirus disease 19 infection, Inflammatory disease colchicine (Perrigo) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Instituto Nacional de Ciencias Medicas y Nutricion Mexico 2020-04-27 2021-04-27 337420-21-1, ColchiVID, NCT04367168 Phase 2 Clinical Not yet recruiting 1 12 Months 174 Jose J Torres-Ruiz, MD, MSc, Marina Rull-Gabayet, MD 2020-05-05
Performance of 3 Sampling Methods for the Detection of SARS-CoV-2 (COVID-19) With Real-time Reverse Transcriptase PCR Coronavirus disease 19 infection Dry flocked nasopharyngeal Swab alone, Flocked nasopharyngeal eSwab alone, Flocked oropharynx eSwab alone Healthy volunteers accepted Jessa Hospital Belgium 2020-04-20 2020-05-20 20.43, NCT04361448 Phase Not Applicable Not yet recruiting 1 1 Month 30 Koen Magerman, Reinoud Cartuyvels 2020-05-04
COHORT: Covid-19 Hospitalized Patients Registry Coronavirus disease 19 infection University Hospital Halle Germany 2020-05-03 2020-039, COHORT, DRKS00021575 Phase Not Applicable Not yet recruiting 1 750 Daniel Sedding 2020-05-01
COVBIO: Thrombosis and Covid-19 Coronavirus disease 19 infection, Thrombosis thromboelastometry alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospices Civils De Lyon France 2020-05-31 2020-12-31 69HCL20_0401 - COVBIO, COVBIO, ID-RCB, NCT04366778 Phase Not Applicable Not yet recruiting 1 7 Months 300 Yesim DARGAUD, Pr, Yseim DARGAUD, Pf 2020-05-01
Social Media and COVID-19 Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Yale-NUS College Singapore 2020-03-08 2020-05-31 2020-CERC-001B, NCT04367363 Phase Not Applicable Recruiting 1 2 Months 150 Jean Liu, PhD 2020-05-01
Cardiac Injury in COVID-19: a Pathology Study Coronavirus disease 19 infection, Heart injury, Lung disease, Myocardial infarction, Myocarditis, Pulmonary heart disease EKG alone, RNAscope in situ hybridization alone, autopsy alone, cardiac catheterization alone, cardiac sampling alone, dual immunofluorescence alone, echocardiography alone, reverse transcription polymerase chain reaction alone, transmission electron microscopy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ospedale Papa Giovanni XXIII CVPath Institute Italy 2020-04-30 2021-03-31 56/20, NCT04367792 Phase Not Applicable Recruiting 1 11 Months 50 Andrea Gianatti, MD, Antonio Bellasi, MD, CTC CLINICAL TRIAL CENTER, Giulio Guagliumi, MD, Lara Faggi, PhD 2020-05-04
MARCO: A Phase Ib/II, Randomized, Placebo-Controlled, Dose-Finding Study Followed by a Dose Level Expansion to Assess the Safety and Efficacy of NoveCite MSCs in Subjects with Acute Respiratory Distress Syndrome (ARDS) Due to SARS-CoV-2 Disease (COVID-19) Coronavirus disease 19 infection, Respiratory distress syndrome Allogeneic NoveCite mesenchymal stem cell therapy (acute respiratory distress syndrome/COVID-19), Citius Pharmaceuticals alone Citius Pharmaceuticals Inc US MARCO Phase 1/Phase 2 Clinical Planned 0 2020-05-04
X-Covid 19: Comparison of Two Doses of Enoxaparin for Thromboprophylaxis in Hospitalized COVID-19 Patients Coronavirus disease 19 infection, Thromboembolism enoxaparin sodium alone Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Niguarda Hospital Italy 2020-05-31 2020-11-30 2020-001708-41, NCT04366960, X-Covid 19 Phase 3 Clinical Not yet recruiting 1 6 Months 2712 Nuccia Morici, MD 2020-05-02
A double-blinded, randomized and placebo-controlled study of trans sodium crocetinate (intravenous), Diffusion Pharmaceuticals in hospitalized COVID-19 patients who have not yet been admitted to an ICU Coronavirus disease 19 infection trans sodium crocetinate (intravenous), Diffusion Pharmaceuticals alone Diffusion Pharmaceuticals LLC, West Virginia University Healthcare US, Eastern Europe Phase Not Applicable Planned 0 Dr. Alex Kadl, Dr. Andrew Southerland 2020-04-30
Intermediate-size Expanded Access Program (EAP), Mesenchymal Stromal Cells (MSC) for Acute Respiratory Distress Syndrome (ARDS) Due to COVID-19 Infection Coronavirus disease 19 infection, Respiratory distress syndrome remestemcel-L alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mesoblast International Sarl Mesoblast Ltd US MSB-MSC-ARDS001, NCT04366830 Phase Not Applicable No longer recruiting 0 50 Mahboob Rahman, MD 2020-05-02
A phase I/II clinical trial for inactivated novel coronavirus (2019-CoV) vaccine (Vero cells) Coronavirus disease 19 infection COVID-19 vaccine (inactivated, Vero cells/intramuscular), Beijing Biological Products Institute/National Institute for Viral Disease Control and Prevention of Chinese Center for Disease Control and Prevention alone Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Beijing Biological Products Institute Co Ltd, China National Pharmaceutical Group Corporation, Henan Center for Disease Control and Prevention Ministry of Science and Technology of the People´s Republic of China China 2020-04-28 2021-11-28 ChiCTR2000032459 Phase 1/Phase 2 Clinical Recruiting 1 19 Months 2128 Wei Wang, Yanxia Wang 2020-05-06
LUCID: Lung Ultrasound in Covid-19 Pneumonia Coronavirus disease 19 infection, Cough, Dyspnea, Respiratory disease, Viral pneumonia computed tomography alone, lung ultrasoound alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Vivantes Humboldt-Klinikum Germany 2020-04-24 DRKS00021585, Eth08-20, LUCID Phase Not Applicable Recruiting 1 220 Andreas Umgelter 2020-05-02
SARS-CoV-2 and Surgery Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Jagiellonian University Poland 2020-03-30 2020-07-01 1072.6120.103.2020, NCT04368026 Phase Not Applicable Recruiting 2 3 Months 350 Tomasz Stefura, Tomasz Stefura, MD 2020-05-02
A larger, double-blinded, randomized, placebo-controlled study of trans sodium crocetinate (intravenous) to confirm safety in COVID-19 patients who have been admitted to Intensive Care Units (ICUs) Coronavirus disease 19 infection trans sodium crocetinate (intravenous), Diffusion Pharmaceuticals alone Diffusion Pharmaceuticals LLC, West Virginia University Healthcare US Phase Not Applicable Planned 0 Dr. Alex Kadl, Dr. Andrew Southerland 2020-04-30
COR-DIAL-1: Rapid Detection of COVID-19 by Portable and Connected Biosensor Coronavirus disease 19 infection RT-PCR alone, nasopharyngeal swab sampling alone, viral biosensor alone Centre Hospitalier Regional Universitaire de Lille France 2020-05-31 2020-09-30 2020-A01147-32, 2020_36, COR-DIAL-1, NCT04367142 Phase Not Applicable Not yet recruiting 1 4 Months 200 David Devos, MD,PhD, Enagnon Kazali ALIDJINOU, MD 2020-05-02
MolCOVID: Development of a Molecular Diagnostic Strategy for SARS-CoV2 Based on Saliva in the Context of the COVID-19 Pandemic Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Boisguillaume France 2020-04-30 2020-05-31 2020/0094/OB, MolCOVID, NCT04367545 Phase Not Applicable Recruiting 1 1 Month 50 Julien BLOT, Thierry FREBOURG, Pr 2020-05-01
EVIDENCE: COVID-19 Detection Test in Oncology Coronavirus disease 19 infection, Solid tumor enzyme-linked immunosorbent assay (ELISA) alone, rapid diagnostic test (RDT) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The UNICANCER Group France 2020-05-31 2021-05-31 2020-A01002-37, EVIDENCE, NCT04367870, UC-TRA-2002 Phase Not Applicable Not yet recruiting 11 12 Months 2500 Alexandra JACQUET, Aurélien NORET, François-Clément BIDARD, Frédéric VIRET, Georges EMILE, Jean-Baptiste BACHET, Jean-Marc FERRERO, Lionel MOREAU, WILLIAM JACOT 2020-05-03
ScreenNC: A Study to Determine the Number of Asymptomatic Individuals Who Have Antibodies to the Virus That Causes COVID-19 Coronavirus disease 19 infection COVID-19 testing alone, PCR test alone, sequencing alone, swab test alone, viral load testing alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of North Carolina US 2020-04-28 2021-04-30 20-0937, NCT04367740, ScreenNC Phase Not Applicable Recruiting 0 12 Months 10000 David B Peden, MD 2020-05-01
ACCORD: ACcelerating COVID-19 Research and Development platform Coronavirus disease 19 infection bemcentinib alone Axl tyrosine kinase receptor inhibitor BerGenBio AS Department of Health and Social Care, IQVIA Holdings Inc, United Kingdom Research & Innovation UK ACCORD Phase 2 Clinical Not yet recruiting 1 120 2020-05-05
BACT-ovid: Bacteriotherapy in the Treatment of COVID-19 Coronavirus disease 19 infection bacteriotherapy alone, Variable regimens including SivoMixx , azithromycin , darunavir , darunavir + cobicistat , hydroxychloroquine , lopinavir + ritonavir , ritonavir Cytochrome P450 3A4 inhibitor, HIV protease inhibitor, HIV-1 protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universita degli Studi di Roma La Sapienza Italy 2020-03-01 2020-07-31 BACT-ovid, DPHID-UNIROMA05, NCT04368351 Phase Not Applicable No longer recruiting 1 5 Months 70 Gabriella d'Ettorre, MD, PhD, Giancarlo Ceccarelli 2020-05-05
Comorbidites among COVID-19 Mortality Cases Coronavirus disease 19 infection National Institutes of Health Malaysia Malaysia 2020-04-30 54554, NMRR-20-766-54554 Phase Not Applicable Status not specified 1 Hamizatul Akmal Binti Abd Hamid, P Robert Lourdes, Tania Gayle 2020-05-01
Influenza Vaccination, ACEI and ARB in the Evolution of SARS-Covid19 Infection Coronavirus disease 19 infection angiotensin converting enzyme inhibitor therapy alone, angiotensin-receptor blocker therapy alone, influenza vaccine alone Healthy volunteers accepted Consorci Sanitari de Terrassa Catalan Health Service, Jordi Gol i Gurina Foundation Spain 2020-03-01 2023-08-31 02-20-161-021, NCT04367883 Phase Not Applicable Recruiting 1 42 Months 2574 Anna Puigdellívol-Sánchez, Ph D, Anna Puigdellívol-Sánchez, Ph.D., Mar Muñoz 2020-05-02
Health Behavior Change During COVID-19 Pandemic Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) SWPS University of Social Sciences and Humanities Poland, China, Singapore, France, Italy, Portugal, Gambia, Romania, Israel, Germany, Switzerland, Canada, Australia, Malaysia 2020-03-25 2021-03-24 3228-1BPSYPSBEH-30, NCT04367337 Phase Not Applicable Recruiting 14 12 Months 5600 Adriana Baban, PhD, Aleksandra Luszczynska, PhD, Bruno Quintard, PhD, Charles Abraham, PhD, Jan Keller, PhD, Karen Morgan, PhD, Katarzyna Byrka, PhD, Konstadina Griva, PhD, Konstantin Schenkel, MA, Margarida Gaspar de Matos, PhD, Martyna Kuszneruk, MA, Michelle Jongenelis, PhD, Nina Knoll, PhD, Noa Vilchinsky, PhD, Sabrina Cipolletta, PhD, Stephan Dombrowski, PhD, Urte Scholz, PhD, Vishna Shah, PhD, Yiquin Gan, PhD, Yiqun Gan, PhD, Zofia Szczuka, MA 2020-05-02
Stigmatization of Covid-19 patients Coronavirus disease 19 infection Hospital Raja Permaisuri Bainun Malaysia 2020-06-01 54697, NMRR-20-777-54697 Phase Not Applicable Status not specified 1 Chang Chee Tao, Ms. Chew Chii Chii 2020-05-02
Psychological Impairment Due to Covid-19 Anxiety disorder, Coronavirus disease 19 infection, Depression, Psychiatric disorder Healthy volunteers accepted Universitatsklinikum Essen 2020-05-06 2020-05-30 NCT04368312, TEMP553914-BO Phase Not Applicable Not yet recruiting 0 100 Johannes Siebermair, MD 2020-05-02
COVIVA: COVID-19 Survival Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Basel Switzerland 2020-03-19 2021-06-30 COVIVA, NCT04366765, UHOSPITAL SWITZ Phase Not Applicable Recruiting 3 15 Months 1500 Christian Mueller, MD, Christian Nickel, MD, Gabriela Kuster Pfister, MD, Hans Pargger, MD, Katharina Rentsch-Savoca, MD, Martin Siegemund, MD, Mirjam Christ Crain, MD, Raphael Twerenbold, MD, Roland Bingisser, MD, Sarah Tschudin-Sutter, MD, Stefan Osswald, MD, Stefano Bassetti, MD 2020-05-05
SAVIOR: Study Assessing Vagus Nerve Stimulation in COVID-19 Respiratory Symptoms Coronavirus disease 19 infection, Respiratory disease GammaCore alone, vagus nerve stimulation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Valencia Spain 2020-04-20 2020-07-31 NCT04368156, SAVIOR, SAVIOR Phase Not Applicable Recruiting 1 3 Months 90 Carlos Tornero, Carlos Tornero, PhD, Natividad Pozo, PhD 2020-05-01
IMPROVE: Intermediate or Prophylactic-Dose Anticoagulation for Venous or Arterial Thromboembolism in Severe COVID-19 Coronavirus disease 19 infection, Thromboembolism enoxaparin sodium alone, unfractionated heparin alone Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Columbia University US 2020-05-31 2021-04-30 AAAS8980, IMPROVE, NCT04367831 Phase 4 Clinical Not yet recruiting 0 11 Months 100 Ajay Kirtane, MD, Kate Dalton, Sahil A. Parikh, Sahil Parikh, MD 2020-05-04
Registry to Study Factors That May Impact COVID-19 Occurrence and Severity Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) IQVIA RDS Pty Ltd US 2020-04-02 2022-06-01 IQVIA-COVIDREGISTRY-2020, NCT04368065 Phase Not Applicable Recruiting 0 26 Months 100000 Barbara Arone, MS, Nancy Dreyer, PhD, MPH 2020-05-01
Use of Convalescent Plasma in the treatment of COVID-19 Coronavirus disease 19 infection convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) HILTON PHARMA (PVT) LTD, National Institute of Blood Disease Center Iran 2020-04-14 4-87/NBC-COVID19-/20/03, IRCT20200414047072N1 Phase 2 Clinical Recruiting 1 357 Dr. Arshi Naz, Dr. Neeta Maheshwary, Professor Dr. Tahir S Shamsi, Saba Fatima 2020-05-01
ATTRACT: A phase II, randomized, double-blind, placebo-controlled clinical trial of VP-01 for the tretment of patients with COVID-19, SARS CoV-2 infection Coronavirus disease 19 infection, Respiratory failure VP-01 alone Angiotensin II AT-2 receptor agonist Vicore Pharma AB UK ATTRACT Phase 2 Clinical Not yet recruiting 1 100 Professor Joanna Porter 2020-04-30
Chula Covid-19 Rapid Test for Pandemic Control Coronavirus disease 19 infection RT-PCR alone Healthy volunteers accepted Burapha University, Chaophraya Yommaraj Hospital, Chulalongkorn University, H.R.H. Maha Chakri Sirindhorn Medical Center, King Chulalongkorn Memorial Hospital, Lampang Hospital, Nan Hospital, National Cancer Institute, Thailand, Paholpolpayuhasena Hospital, Police General Hospital, Samitivej Sukhumvit Hospital, Samut Sakhon Hospital, Sikhio Hospital, Songkhla Hospital Thailand 2020-03-20 TCTR20200426002 Phase Not Applicable Recruiting 1 200 Krit Pongpirul, Narin Hiransuthikul 2020-05-05
Intravascular Access in Suspected/Confirmed COVID-19 Patient Cardiac arrest, Coronavirus disease 19 infection NIO needle set alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Lazarski University Medical University of Bialystok, Poznan University of Medical Sciences, Wroclaw Medical University Poland 2020-04-14 2020-05-20 IO_PPE_1, NCT04366947 Phase Not Applicable No longer recruiting 1 1 Month 60 Lukasz Szarpak, Lukasz Szarpak, PhD 2020-05-01
COVID-19BRAIN: Neuroradiolological Analysis of COVID-19 Patients Brain disease, Coronavirus disease 19 infection neurological examination alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopitaux Universitaires de Strasbourg France 2020-04-03 2021-04-30 7759, COVID-19BRAIN, NCT04368390 Phase Not Applicable Recruiting 1 12 Months 100 Saïd CHAYER, PhD, HDR, Stephane Kremer, MD, PhD, Stéphane KREMER, MD, PhD 2020-05-01
A clinical trial of recombinant protein vaccine for the prevention of COVID-19 infection Coronavirus disease 19 infection recombinant protein vaccine (COVID-19), UMN Pharma Inc alone Shionogi & Co Ltd Japan Phase Not Applicable Planned 1 2020-04-30
Clinical Validation of New Injection Molded Flocked Nasopharyngeal Swabs in Response to the COVID-19 Pandemic Coronavirus disease 19 infection injection molded polypropylene flocked nylon nasopharyngeal swab alone Healthy volunteers accepted, Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Virginia US 2020-04-24 2020-07-31 HSR200127, NCT04368260 Phase Not Applicable Recruiting 0 3 Months 40 Amy Mathers, MD, Limor Steinberg 2020-05-01
COVIDSMELL: Study of the Pathogenesis of Olfactory Disorders in COVID-19 Ageusia, Coronavirus disease 19 infection, Dysomia nasal swab sampling alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institut Pasteur Assistance Publique Hopitaux de Paris France 2020-04-30 2022-09-15 2020-021, COVIDSMELL, NCT04366934 Phase Not Applicable Not yet recruiting 1 28 Months 24 Charlotte HAUTEFORT, MD, Françoise LAZARINI, PhD 2020-05-01
RESCUE 1-19: Radiation Eliminates Storming Cytokines and Unchecked Edema as a 1-Day Treatment for COVID-19 Coronavirus disease 19 infection, Edema, Viral pneumonia low dose radiation therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Emory University National Cancer Institute US 2020-04-23 2020-07-01 NCI-2020-02676, NCT04366791, P30CA138292, RAD5002-20, RESCUE 1-19, STUDY00000476 Phase 1/Phase 2 Clinical Recruiting 0 2 Months 10 Autumn Lunceford, Clayton B Hess, MD, MPH, Clayton B. Hess, Clayton B. Hess, MD MPH, Clayton Hess, MD, MPH, Mohammad K Khan, MD, PhD, Mohammad K. Khan, MD PhD 2020-05-02
Prospective Registry of Corona Virus Disease 2019 (Covid-19) Patients With Neuromuscular Involvement Coronavirus disease 19 infection electromyography alone, electroneurography alone, muscle ultrasound alone, transthoracic echocardiography alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Tubingen Germany 2020-03-20 2022-03-31 246/2020BO2, NCT04367350 Phase Not Applicable Recruiting 1 24 Months 500 Alexander Grimm, MD, Helene Häberle, MD, Markus Krumbholz, MD, Sophia Willikens, MD, Sven Poli, MD 2020-05-01
African Covid-19 Critical Care Outcomes Study Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Cape Town University Of Kwazulu-Natal South Africa 2020-05-01 2020-12-31 ACCCOS, NCT04367207 Phase Not Applicable Not yet recruiting 1 8 Months 2000 Bruce Biccard, Bruce M Biccard 2020-05-01
DEPRECOVID: Impact of Giving Birth During the Covid 19 Pandemia on Postnatal Women's Depression Anxiety disorder, Coronavirus disease 19 infection, Depression, Gynecological disorder Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire De Poitiers Etablissement D’Hospitalisation France 2020-05-31 2020-12-31 2020-A01065-34, DEPRECOVID, NCT04368208 Phase Not Applicable Not yet recruiting 1 7 Months 900 bertarnd GACHON, MD, PhD student 2020-05-04
IRCEP: International Registry of Coronavirus (COVID-19) Exposure in Pregnancy Coronavirus disease 19 infection Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Pregistry Harvard TH Chan School of Public Health US 2020-05-01 2024-04-30 0001, IRCEP, NCT04366986 Phase Not Applicable Not yet recruiting 0 48 Months 25000 Diego Wyszynski, MD, MHS, PhD, Sonia Hernandez-Diaz, MD, DrPH 2020-05-01
reCoVery: Repurposing of Chlorpromazine in Covid-19 Treatment Coronavirus disease 19 infection chlorpromazine alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Sainte Anne Hôpital Cochin France 2020-04-29 2020-09-30 D20-P016, NCT04366739, reCoVery Phase 3 Clinical Not yet recruiting 1 5 Months 40 Marion Plaze, MD, PHD, Raphaël Gaillard, MD, PHD 2020-05-01
COVCKD: Antibody Response Against SARS-CoV-2 in Dialysis Patients During COVID-19 Coronavirus disease 19 infection, Kidney dialysis Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Region Midtjylland Aalborg Hospital, Aarhus University Hospital, Central Jutland Regional Hospital Denmark 2020-03-15 2021-12-01 COVCKD, FHM-1-2020, NCT04367714 Phase Not Applicable Recruiting 1 20 Months 300 Frank Mose, Frank Mose, MD 2020-05-01
MY-CO-VID: Characterization of Fungal Infections in COVID-19 Infected and Mechanically Ventilated Patients in ICU Aspergillus infection, Coronavirus disease 19 infection, Mucor infection, Pneumocystis carinii infection biological sampling alone, polymerase chain reaction alone, real-time polymerase chain reaction alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rennes University Hospital France 2020-04-30 2021-05-31 35RC20_8885_MY_CO_VID, MY-CO-VID, NCT04368221 Phase Not Applicable Not yet recruiting 15 13 Months 250 Achille Kouatchet, Alain Mercat, Anna Novara, Antoine Berry, Beatrice Riu-Poulenc, Carole Schwebel, Christophe Hennequin, Cécile Aubron, Daniele Monbon, Emmanuel Canet, Eric Dannaoui, Feraht Meziani, Florence Persat, Florence Robert-Gangneux, Florent Morio, Francoise Botterel, Frederic Dalle, Frédéric Dalle, Gilles Nevez, Gilles Nevez Nevez, Guillaume Desoubeaux, Jean Christophe Richard, Jean-Francois Timsit, Jean-Marc Tadié, Jean-Philippe Bouchara, Jean-Pierre GANGNEUX, MD, PhD, Jean-Pierre Gangneux, Keyvan Razazi, Laurent Argaud, Marie LE NAOU, Martine Wallon, Muriel Cornet, Muriel Sarrah Fartoukh, Nicolas Terzi, Nicolas de Prost, Patrice Le Pape, Pierre-Francois Dequin, Pierre-François Dequin, Sandrine Houzé, Sophie Brun, Stephane Gaudry, Stéphane Gaudry, Valerie Letcher-Bru, Valérie Letcher-Bru, Xavier Iriart, Yves Cohen, Yves Le Tulzo, cecile Aubron, cécile Aubron 2020-05-04
THROMBOCOVID: Thrombo Embolic Events in Critical Care Patients With Covid-19 Serious Acute Pneumopathy Coronavirus disease 19 infection, Lung disease, Thromboembolism, Viral pneumonia venous ultrasound alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire D Amiens France 2020-04-22 2020-09-22 NCT04366752, PI2020_843_0036, THROMBOCOVID Phase Not Applicable Recruiting 1 5 Months 100 Clement Brault, MD, Julien Maizel, Pr, Michel Slama, Pr, Simon Soudet, MD, Yoann Zerbib, MD 2020-05-01
IMSEQ: COVID-19 Immune Repertoire Sequencing Coronavirus disease 19 infection blood sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institute of Tropical Medicine, Belgium Antwerp University Hospital Belgium 2020-04-01 2020-12-31 IMSEQ, IMSEQ, NCT04368143 Phase Not Applicable Recruiting 1 9 Months 100 Koen Vercauteren 2020-05-01
The effect of NBS powder in treatment of patients with COVID-19 Coronavirus disease 19 infection NBS powder alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hamadan University of Medical Sciences Iran 2020-05-09 IR.UMSHA.REC.1399.046, IRCT20200426047206N1 Phase 3 Clinical Not yet recruiting 1 46 Farid Azizi Jalilian 2020-05-04
PIC-19: Enhanced Platelet Inhibition in Critically Ill Patients With COVID-19 Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia Variable regimens including acetylsalicylic acid , clopidogrel , fondaparinux sodium , tirofiban Factor Xa antagonist, GP IIb IIIa antagonist, P2Y12 purinoceptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universita degli Studi di Milano Fondazione Un Cuore per Milano Italy 2020-04-06 2020-04-23 18275/2020, NCT04368377, PIC-19 Phase 2b Clinical Completed 1 5 Pierachille Santus 2020-05-02
Effect of natural from Tahini oil product on corona Coronavirus disease 19 infection Tahini oil alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gonabad University of Medical Sciences Iran 2020-04-30 IR.GMU.REC.1399.014, IRCT20140407017169N2 Phase 0 Clinical Recruiting 1 100 Ahmadi Reza, Hossein Mohammadzadeh- Moghadam, Hossein Mohammadzadeh-moghadam 2020-05-05
BEVACOR: Pilot study of bevacizumab as a treatment for respiratory distress in patients with COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome bevacizumab alone VEGF ligand inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundación Para La Investigación Biomédica De Córdoba Spain 2020-04-24 2020-001541-39, BEVACOR, BEVACOR Phase 2 Clinical Recruiting 1 22 Antonio Luque 2020-05-01
Is there a benefit in treating novel corona virus (Sars-CoV2) infections with the established antihypertensive valsartan? Coronavirus disease 19 infection valsartan alone Angiotensin I receptor antagonist, Angiotensin II receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Klinikum St Georg Germany 2020-04-22 2020-001431-27, CovidVal01 Phase 2 Clinical No longer recruiting 1 300 Geschäftsführung 2020-05-04
Telemedicine in the Covid-19 pandemic in Brazil in a medical clinic in the supplementary health sector in São Paulo, Brazil Coronavirus disease 19 infection telemedicine alone, azithromycin plus hydroxychloroquine Centro Medico Mazzei Brazil 2020-04-01 3.947.259, 30246520.0.0000.0069, A36899523876, RBR-658khm Phase 2 Clinical Recruiting 1 90 Michelle Chechter 2020-05-01
SIDIACO: The Effect of Sitagliptin Treatment in COVID-19 Positive Diabetic Patients Coronavirus disease 19 infection, Non-insulin dependent diabetes, Respiratory failure, Viral pneumonia nutrition intake alone, sitagliptin alone, standard of care alone, insulin plus sitagliptin Dipeptidyl peptidase IV inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universita degli Studi di Milano Italy 2020-04-30 2020-12-30 FBF SACCO, NCT04365517, SIDIACO Phase 3 Clinical Not yet recruiting 1 8 Months 170 Paolo Fiorina, MD, PhD, Teresa Letizia, Dr. 2020-05-02
MERMAIDS 2: European Study of Major Infectious Disease Syndromes Related to COVID-19 Coronavirus disease 19 infection, Respiratory disease, Respiratory tract infection biological sampling alone Universitair Medisch Centrum Utrecht Netherlands 2020-05-01 2022-04-30 MERMAIDS 2, NCT04364711, RECOVER - MERMAIDS 2.0 Phase Not Applicable Not yet recruiting 1 24 Months 2000 MJM Bonten 2020-04-30
Intravascular Access of COVID-19 Patient Under Personal Protective Equipment Coronavirus disease 19 infection NIO alone, Standard intravenous cannula alone, intraosseous access alone, intravenous access alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Lazarski University Medical University of Bialystok, Poznan University of Medical Sciences, Wroclaw Medical University Poland 2020-01-12 2020-02-25 IO_PPE_MS_1, NCT04366297 Phase Not Applicable Completed 1 1 Month 41 Jacek Smereka, PhD, Łukasz Szarpak, Assoc Prof PhD 2020-04-30
PROBIOZOVID: Oxygen-Ozone as Adjuvant Treatment in Early Control of COVID-19 Progression and Modulation of the Gut Microbial Flora Coronavirus disease 19 infection oxygen-ozone therapy alone, standard of care alone, Variable regimens including Ozone , SivoMixx , azithromycin , darunavir , darunavir + cobicistat , hydroxychloroquine , lopinavir + ritonavir , ritonavir Cytochrome P450 3A4 inhibitor, HIV protease inhibitor, HIV-1 protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Azienda Policlinico Umberto I Italy 2020-03-26 2020-12-31 110/2020, NCT04366089, PROBIOZOVID Phase 2 Clinical Recruiting 1 9 Months 152 Andrea Calò, MD, Carmela Imperiale, MD, Claudio M Mastroianni, MD PhD, Fabio Araimo, MD, Francesco Pugliese, MD PhD, Francesco Pugliese, MD, PhD, Gabriella d'Ettorre, MD PhD, Giancarlo Ceccarelli, MD PhD MSc, Gregorio Egidio Recchia, MD, Paolo Tordiglione, MD PhD, Roberto Poscia MD, Serena Zancla, MD, Vera MAuro, MD 2020-05-01
The University of the Philippines Hydroxychloroquine PEP Against COVID-19 Trial Coronavirus disease 19 infection hydroxychloroquine alone, standard preventive measures alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) University of the Philippines Philippines 2020-05-31 2021-05-31 NCT04364815, RGAO-2020-0339 Phase 3 Clinical Not yet recruiting 1 12 Months 960 Belen L Dofitas, MD 2020-05-06
COVID-19 Seremban 3MCO Coronavirus disease 19 infection Pejabat Kesihatan Daerah Seremban Malaysia 2020-04-29 2020-09-01 54671, NMRR-20-786-54671 Phase Not Applicable Recruiting 1 4 Months Dr MOHD 'AMMAR IHSAN BIN AHMAD ZAMZURI 2020-05-01
COVID-T: COVID-19 Search in Conjunctival Cells Coronavirus disease 19 infection, Lung disease computed tomography alone, conjunctival swab alone, nasopharyngeal swab alone, real time-PCR alone, x-ray alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Policlinico Universitario Agostino Gemelli Italy 2020-03-26 2020-05-30 0013008/20, COVID-T, NCT04364594 Phase Not Applicable No longer recruiting 1 2 Months 50 2020-04-30
SCOPe: To Study the Clinical characteristics and treatment Outcome of COVID-19 Patients admitted in hospitals of Max Healthcare Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Max Super Speciality Hospital India 2020-04-25 CTRI/2020/04/024859, SCOPe Phase Not Applicable Not yet recruiting 1 1000 Dr Ram Shankar Mishra, Dr Sandeep Budhiraja, Rajesh Saxena 2020-04-29
PRON-COVID: The Prone Position in Covid-19 Affected Patients Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia continuous positive airway pressure therapy alone, oxygen therapy alone, prone positioning alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Milano-Bicocca Italy 2020-03-20 2020-05-31 NCT04365959, PRON-COVID, PRON-COVID Phase Not Applicable No longer recruiting 1 2 Months 56 Giuseppe Foti, Prof. 2020-05-01
To study the effectiveness of Ivermectin with standard of care treatment versus standard of care treatment for COVID-19 cases. A Pilot Study Coronavirus disease 19 infection ivermectin alone Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Max Super Speciality Hospital India 2020-04-25 CTRI/2020/04/024858 Phase 2 Clinical Not yet recruiting 1 50 Dr Ram Shankar Mishra, Dr Sandeep Budhiraja, Rajesh Saxena 2020-04-29
Bid data analytic COVID-19 Coronavirus disease 19 infection predictive visual analytic method alone National Institutes of Health Malaysia Malaysia 2020-04-30 2020-08-31 54648, NMRR-20-790-54648 Phase Not Applicable Not yet recruiting 1 4 Months Dr Mohd Azahadi Omar, Encik MOHAMAD FUAD BIN MOHAMAD ANUAR 2020-04-29
RNA-based vaccine for COVID-19 Coronavirus disease 19 infection RNA-based vaccine alone Institute For Medical Research (Inc In Malaysia) Malaysia 2020-06-01 2022-12-31 54569, NMRR-20-764-54569 Phase Not Applicable Status not specified 1 31 Months Dr MASITA BINTI ARIP, Ms Ching Yee Ming 2020-04-30
COVID-19 NGS: NGS Diagnostic in COVID-19 Hosts: Genetic Cause Relating to the Course of Disease Progression Coronavirus disease 19 infection DNA methylation analysis alone, T-cell receptor repertoire sequencing alone, methylation beadchip (EPIC) array alone, next generation sequencing alone, whole genome sequencing alone, whole transcriptome sequencing alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Tubingen Germany 2020-04-30 2021-08-31 COVID-19 NGS, COVID-19 NGS, NCT04364828 Phase Not Applicable Not yet recruiting 1 16 Months 1000 Michael Bitzer, Prof. Dr., Olaf Rieß, Prof. Dr. 2020-05-04
COVID-19: investigation into biochemical and hematological parameters in clinical laboratory Coronavirus disease 19 infection UNIVERSITI INDUSTRI SELANGOR (UNISEL) - SHAH ALAM CAMPUS Malaysia 2020-04-29 2020-05-29 54641, NMRR-20-760-54641 Phase Not Applicable Status not specified 1 1 Month CHIA ZHEN ZHAN 2020-04-29
Lung Recruitment Device for COVID-19 Coronavirus disease 19 infection Chest physiotherapy alone Dymedso Inc, Fonds de la Recherche en Sante du Quebec 2020-05-01 2020-12-31 MP-21-2020-2871, NCT04361435 Phase Not Applicable Not yet recruiting 0 8 Months 50 Atsushi Kawaguchi, MD PhD, Philippe Jouvet, MD PhD MBA, Saly Salti, MSc 2020-04-30
LAPTRANSCOV: Assessment of the Presence of the SARS-COV-2 Virus in the Peritoneum of COVID-19 Patients Coronavirus disease 19 infection RT-PCR alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier René-Dubos France 2020-05-31 2020-10-31 CHRD 0420, LAPTRANSCOV, NCT04361396 Phase Not Applicable Recruiting 2 5 Months 40 Christophe Poncelet, Maryline Delattre, Nelson Trelles, Veronique Da Costa 2020-05-01
Loneliness During the NPIs for the COVID-19 Pandemic in Norway: Risk Factors and Associations With Psychopathology Anxiety disorder, Coronavirus disease 19 infection, Depression, Psychiatric disorder non-pharmacological intervention treatment alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Modum Bad University of Oslo Norway 2020-03-31 2020-04-07 NCT04365881, REK12345 Phase Not Applicable Completed 1 10084 Asle Hoffart, PhD, Omid V. E. Ebrahimi, Cand Psychol, Sverre Urnes Johnson, PhD 2020-05-01
NutriCovid30: Nutritional Evaluation for Covid-19 Infection at D30 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Grenoble Universite Grenoble Alpes France 2020-05-31 2020-11-30 2020-A01120-39, NCT04365816, NutriCovid30 Phase Not Applicable Not yet recruiting 1 6 Months 600 Marie-France VAILLANT, PhD 2020-05-04
AIC: Azithromycin in Hospitalized COVID-19 Patients Coronavirus disease 19 infection azithromycin alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shaheed Beheshti Medical University Iran 2020-04-20 2020-05-05 AIC, AZITHROMYCIN IN COVID-19, NCT04359316 Phase 4 Clinical Not yet recruiting 1 40 Mehran Lack, MD, Mohammad Fathi, MD, Nader Markazi, MD, Nasser Malekpour Alamdari, MD, Sanaz Zargar Balaye Jam, MD, Sasan Tavana, MD, Seyed Sina Naghibi Irvani, MD, MPH, MBA 2020-04-29
An International, multicenter clinical study to evaluate the efficacy and safety of Polyoxidonium in hospitalized COVID-19 patients Coronavirus disease 19 infection Polyoxidonium alone NPO Petrovax Pharm LLC Russian Federation Phase Not Applicable Not yet recruiting 1 2020-04-29
CYNK001COVID: Natural Killer Cell (CYNK-001) Infusions in Adults With COVID-19 Coronavirus disease 19 infection, Lower respiratory tract infection CYNK-001 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Celularity Inc, Sorrento Therapeutics Inc Infectious Disease Research Institute, Lung Biotechnology Inc US 2020-04-30 2021-11-30 CYNK-001-COVID-19, CYNK001COVID, NCT04365101 Phase 1/Phase 2 Clinical Not yet recruiting 0 19 Months 86 Corey Casper, MD MPH, Erica Rave, MS, IDRI 2020-04-29
OzonoCOVID19: Indirect Endovenous Systemic Ozone for New Coronavirus Disease (COVID 19) in Non-intubated Patients Coronavirus disease 19 infection Base WHO recommended treatment. alone, Systemic indirect endovenous ozone therapy alone, ozone alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidad Católica San Antonio de Murcia Sociedad Española de Ozonoterapia Spain 2020-04-30 2020-06-30 NCT04359303, OzonoCOVID19, P.INV. OZONO-COVID19 VER.1.2 Phase 3 Clinical Not yet recruiting 1 2 Months 50 Francisco J Hidalgo Tallón, MD, PhD, Jose Baeza Noci, MD, PhD 2020-04-30
COVIDHIV: Clinical Characterization Protocol for COVID-19 in People Living With HIV Coronavirus disease 19 infection, HIV infection auto-questionnaires alone, biological collection alone, qualitative interviews alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-04-30 2020-10-31 2020-A00984-35, COVIDHIV, NCT04361604 Phase Not Applicable Not yet recruiting 1 6 Months 270 Antoine Chéret, Dr 2020-04-29
A Single-center, Retrospective Study to Find Prediction Factors Related to Mortality of COVID-19 Patients Coronavirus disease 19 infection, Diabetes mellitus, Viral pneumonia multivariate analysis alone, real-time RT-PCR test alone, univariate analysis alone Tongji Hospital China 2020-02-02 2020-04-01 NCT04365634, TJ20200202 Phase Not Applicable Completed 1 2 Months 306 Meifang Han, Professor, Qin Ning 2020-05-02
Metabolon Study to Provide Better Understanding of COVID-19 Coronavirus disease 19 infection Institute For Systems Biology, Metabolon Inc US Phase Not Applicable Status not specified 0 James R. Heath, Ph.D, Jason Goldman, M.D 2020-04-29
HASCOPT: Hydroxychloroquine Azithromycin COVID-19 Pregnancy Trial Coronavirus disease 19 infection, Respiratory failure azithromycin plus hydroxychloroquine Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital St. Joseph, Marseille, France France 2020-04-30 2021-01-31 HASCOPT, HASCOPT2020, NCT04365231 Phase 3 Clinical Not yet recruiting 1 9 Months 50 Laurence CUREL, Maria mg Gackiere, Raoul RD Desbriere, MD, Xavier-Côme xcd Donato 2020-04-29
Effect of RBT-9 on Preventing Progression of COVID-19 in High-Risk Individuals Coronavirus disease 19 infection RBT-9 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Renibus Therapeutics Inc 2020-06-01 2021-12-31 NCT04364763, REN-005 Phase 2 Clinical Not yet recruiting 0 19 Months 252 2020-04-29
A study to assess the efficacy of tocilizumab in severe patients with Corona Virus Disease19 (COVID-19) Coronavirus disease 19 infection routine therapy alone, tocilizumab (intravenous), Roche/Chugai alone IL-6 receptor antagonist, IL-6 receptor modulator 2nd People's Hospital of Fuyang City, Anhui Provincial Hospital China National Center For Biotechnology Development, Department of Science and Technology of Anhui Province China Phase Not Applicable Status not specified 2 21 2020-04-29
COVID-RPC: Observational, Cohort of COVID-19 Patients at Raymond-Poincare Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-04-30 2020-05-31 20SBS-COVID-RPC, COVID-RPC, NCT04364698 Phase Not Applicable Not yet recruiting 1 1 Month 500 Aurelien Dinh, MD, Simon Bessis, MD 2020-04-29
Convalescent Plasma for COVID-19 Coronavirus disease 19 infection, Viral pneumonia convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ente Ospedaliero Cantonale, Switzerland 2020-04-27 2020-06-30 2020-00895, NCT04365439 Phase 2 Clinical Not yet recruiting 2 2 Months 10 Beatrice Bernasconi, Enos Bernasconi, Enos Bernasconi, M.D., Stefano Fontana, M.D. 2020-04-29
Covid-19 Associated Coagulopathy Blood clotting disorder, Coronavirus disease 19 infection enoxaparin sodium alone Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Iowa US 2020-04-16 2021-04-16 202004235, NCT04360824 Phase 4 Clinical Not yet recruiting 0 12 Months 170 Usha Perepu 2020-04-29
Clinical Trial to Evaluate the Efficacy of Treatment With Hyperimmune Plasma Obtained From Convalescent Antibodies of COVID-19 Infection Coronavirus disease 19 infection convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Andalusian Network for Design and Translation of Advanced Therapies Spain 2020-04-30 2021-12-31 NCT04366245, PC/COVID-19 Phase 1/Phase 2 Clinical Recruiting 1 20 Months 72 Ana Cardesa Gil 2020-04-29
Proving the efficacy of Homeopathic treatment in prevention and cure of COVID-19 Coronavirus disease 19 infection Variable regimens including Ars Alb , Bryonia Alba , Camphora , Helleborus niger , Justicia Adhatoda Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Welling Healthcare Private Limited India 2020-05-04 CTRI/2020/04/024857 Phase 1/Phase 2 Clinical Not yet recruiting 1 100 Angelo Smith, Dr Sourabh R Welling 2020-04-29
HIGH-PRONE-COVID-19: Prone Position in Patients on High-flow Nasal Oxygen Therapy for COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia prone decubitus alone, usual care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Tours France 2020-04-27 2020-11-24 2020-A01121-38, DR200125, HIGH-PRONE-COVID-19, HIGH-PRONE-COVID-19, NCT04358939 Phase Not Applicable Recruiting 13 6 Months 248 Agathe DELBOVE, MD, Anne-Charlotte TELLIER, MD, Arnaud THILLE, MD-PhD, Christophe GUITTON, MD, Damien ROUX, MD-PhD, Erwan L'HER, MD-PhD, Gaetan PLANTEFEVE, MD, Guillaume VOIRIOT, MD, Jean DELLAMONICA, MD-PhD, Jean REIGNIER, MD-PhD, Mai-Anh NAY, MD, Saadalla NSEIR, MD, Stephan EHRMANN, MD-PhD, Yoanatan PEREZ, MD, Yonatan PEREZ, MD 2020-04-30
COVID-19 CAir: SARS-CoV-2 Associated Respiratory Failure Recovery Coronavirus disease 19 infection, Respiratory failure Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Zurich Switzerland 2020-05-31 2020-12-31 2020-00745, COVID-19 CAir, NCT04365595 Phase Not Applicable Recruiting 1 7 Months 200 Christian F Clarenbach, MD, Dario Kohlbrenner, MSc 2020-05-05
COP-COVID-19: Convalescent Plasma Compared to the Best Available Therapy for the Treatment of SARS-CoV-2 Pneumonia Coronavirus disease 19 infection, Viral pneumonia convalescent plasma alone, supportive management alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Universitario Dr. Jose E. Gonzalez Mexico 2020-04-27 2021-05-30 COP-COVID-19, IF20-00002, NCT04358783 Phase 2 Clinical Not yet recruiting 1 13 Months 30 Adrian Camacho-Ortiz, MD, Eduardo Pérez Alba, MD, Laura Marina Nuzzolo Shihadeh, MD 2020-04-30
COVID-19 (Coronavirus Disease 2019) Intubation Barrier Box Coronavirus disease 19 infection COVID-19 barrier box alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of British Columbia Canada 2020-05-31 2021-04-30 H20-01270, NCT04366141 Phase Not Applicable Not yet recruiting 1 11 Months 120 Anton Chau, MD, Tim Jen, MD 2020-05-05
A Proof of Concept study of Nu.Q COVID-19 Triage Test in COVID-19 patients Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia Volition’s Nu.QTM nucleosome assays alone VolitionRX Ltd Phase Not Applicable Planned 0 2020-04-29
REP-COVID: Plasma Exchange in Patients With COVID-19 Disease and Invasive Mechanical Ventilation: a Randomized Controlled Trial Coronavirus disease 19 infection Variable regimens including anakinra , azithromycin , enoxaparin sodium , hydroxychloroquine , lopinavir + ritonavir , methylprednisolone , plasma exchange , polyclonal immunoglobulin , serum albumin , tocilizumab HIV protease inhibitor, Low molecular weight heparin, Type I IL-1 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Fundació Clínic Per A La Recerca Biomèdica Instituto de Salud Carlos III Spain 2020-04-23 2021-08-29 2020-001722-66, NCT04374539, REP-COVID, REP_COVID Phase 2 Clinical Recruiting 2 16 Months 116 Anna Cruceta, Anna Cruceta, MD, CTU, Fundacio Hospital Clinic 2020-05-06
JAKINKOV: Efficacy of Intravenous Anakinra and Ruxolitinib During COVID-19 Inflammation Coronavirus disease 19 infection, Inflammatory disease, Respiratory distress syndrome, Viral pneumonia anakinra alone, Jakavi plus Kineret Type I IL-1 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer Assistance Publique Hopitaux De Marseille France 2020-05-01 2020-08-31 2020-001963-10, 2020-CHITS-003, JAKINKOV, NCT04366232 Phase 2 Clinical Not yet recruiting 3 4 Months 50 David DELARBRE, MD, Gilles HITTINGER, MD, Gilles KAPLANSKI, MD, Jean-Philippe Suppini, PhD 2020-04-30
A study to track coronavirus (COVID-19) in the general population Coronavirus disease 19 infection University of Oxford UK Phase Not Applicable Status not specified 1 300000 Department for Health and Social Care, Office for National Statistics 2020-04-29
ESCAPE: Study to evaluate the efficacy and tolerability of treatment with vafidemstat in combination with standard of care treatment to prevent Acute Respiratory Distress Syndrome in adult severely ill patients with COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome standard of care treatment alone, vafidemstat alone Lysine specific histone demethylase 1 inhibitor, MAO B inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Oryzon Genomics SA Spain 2020-04-24 2020-001618-39, CL08-ORY-2001_COVID-19, ESCAPE Phase 2 Clinical No longer recruiting 1 40 Sonia Gutiérrez 2020-04-30
AUTONOMIC: Stress Biomarkers Leading to Professional Burnout Among People Involved in a Mobile Intensive Care Unit During the COVID-19 Pandemic Anxiety disorder, Coronavirus disease 19 infection, Post traumatic stress disorder electrocardiography alone, electrodermal test alone, emotional stimulation test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Direction Centrale du Service de Sante des Armees Institut de Recherche Biomedicale des Armees France 2020-04-30 2020-06-30 2020-COVID19-11, AUTONOMIC, NCT04365335 Phase Not Applicable Recruiting 2 2 Months 60 Damien CLAVERIE, MD, PhD 2020-05-04
SINK COVID-19: Study of Immunomodulation Using Naltrexone and Ketamine for COVID-19 Coronavirus disease 19 infection Ketalar alone, naltrexone (once-monthly controlled-release, Medisorb), Alkermes alone, Ketalar plus naltrexone (once-monthly controlled-release, Medisorb), Alkermes Opioid receptor antagonist, Opioid receptor mu antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) William Beaumont Hospitals US 2020-04-29 2020-08-31 2020-097, NCT04365985, SINK COVID-19 Phase 2 Clinical Recruiting 0 4 Months 500 Matthew Sims, MD, Matthew Sims, MD PhD, Maureen Cooney, RN, BSN 2020-05-05
Convalescent Plasma to Limit COVID-19 Complications in Hospitalized Patients Coronavirus disease 19 infection, Respiratory disease anti-SARS-CoV-2 convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Albert Einstein College of Medicine New York University US 2020-04-17 2023-04-30 2020-11467, NCT04364737 Phase 2 Clinical Recruiting 0 36 Months 300 Hyunah Yoon, MD, Liise-anne Pirofski, MD, Mila Ortigoza, MD 2020-04-30
COVIDIOL: Prevention and Treatment With Calcifediol of COVID-19 Induced Acute Respiratory Syndrome Coronavirus disease 19 infection Hidroferol alone, best available therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundación Para La Investigación Biomédica De Córdoba, Maimonides Biomedical Research Institute of Cordoba Consejeria de Salud. Junta de Andalucia, Dynamic Solutions Inc, FAES Farma SA Spain 2020-04-28 2020-08-28 2020-001717-20, COVIDIOL, COVIDIOL, NCT04366908 Phase 2 Clinical Not yet recruiting 1 4 Months 1008 Antonio Luque, Antonio Luque, MsC, José López Miranda, MD, José Manuel Quesada Gómez, MD 2020-05-01
MESCEL-COVID19: Clinical Trial of Allogeneic Mesenchymal Cells From Umbilical Cord Tissue in Patients With COVID-19 Coronavirus disease 19 infection umbilical cord tissue derived undifferentiated allogeneic mesenchymal cells alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Infantil Universitario Nino Jesus Apices Soluciones, S.L. Spain 2020-04-24 2021-05-31 2020-001450-22, MESCEL-COVID19, MESCEL-COVID19, NCT04366271 Phase 2 Clinical Not yet recruiting 6 13 Months 106 Clara I Rodriguez, MD, Francisco García-Rio, MD, Jose A Lorente Balanza, MD, Julio Ancochea, MD, Luis Madero, MD, Luis Madero, PhD, Maria J del Cerro Marin, MD, Mrs. Laura Aranzasti, Sergio Serrano, MD, Teresa de Rojas, PhD 2020-05-02
REMDECO-19: Multicenter, Retrospective Study of the Effects of Remdesivir in the Treatment of Severe Covid-19 Infections Coronavirus disease 19 infection remdesivir alone Coronavirus non structural protein 8 modulator, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-04-30 2020-05-31 APHP200522, NCT04365725, REMDECO-19 Phase Not Applicable Not yet recruiting 1 1 Month 200 Jeremie ZERBIT, PharmaD, Jérémie ZERBIT, PharmaD 2020-04-30
RAMIC: Ramipril for the Treatment of COVID-19 Coronavirus disease 19 infection ramipril alone ACE inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of California San Diego Pfizer Inc US 2020-04-30 2021-04-30 NCT04366050, RAMIC, RAMIC TRIAL Phase 2 Clinical Not yet recruiting 0 12 Months 560 Archana Bhatt, Len Lazaro, Rohit Loomba 2020-05-02
Progesterone for the Treatment of COVID-19 in Hospitalized Men Coronavirus disease 19 infection progesterone (sc, in vitro fertlilization), Institut Biochimique alone, standard of care alone Progesterone receptor agonist Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cedars-Sinai Medical Center IBSA Institut Biochimique SA US 2020-04-27 2021-04-17 NCT04365127, STUDY00000611 Phase 1 Clinical Recruiting 0 11 Months 40 Sara Ghandehari, MD, Vanessa Vasco 2020-04-30
COVIDMES: Efficacy and safety evaluation of umbilical cord mesenchymal stem cells for the treatment of patients with respiratory failure due to coronavirus (COVID-19) Coronavirus disease 19 infection, Respiratory distress syndrome umbilical cord mesenchymal stem cells alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Banc De Sang I Teixits Spain 2020-04-23 2020-001505-22, BST-COVID-01, COVIDMES Phase 1/Phase 2 Clinical No longer recruiting 1 30 Banc de Sang i Teixits 2020-04-30
BIRCOV: ARB, ACEi, DRi in COVID-19 Coronavirus disease 19 infection, Hypertension angiotensin converting enzyme inhibitor (ACEi) therapy alone, angiotensin receptor blocker (ARB) therapy alone, dopamine reuptake inhibitor (DRI) therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Medical Practice Prof D. Ivanov Ukraine 2020-04-01 2021-08-01 BIRCOV, COVID20, NCT04364984 Phase Not Applicable Recruiting 1 16 Months 10 Dmytro Ivanov, MD, Prof, Mariia Ivanova, MD, PhD 2020-04-30
DURO-SIN: COVID-19 in an academic teaching hospital in Konstanz/Germany - evaluation of the 'double rule out - single rule in' concept Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Klinikum Konstanz, II. Medizin Germany 2020-04-27 81/2020, DRKS00021605, DURO-SIN, U1111-1251-0310 Phase Not Applicable Recruiting 1 200 Stephan Walterspacher 2020-04-30
Factors Associated With Clinical Outcomes in Patients Hospitalized for COVID-19 in GHT-93 Est Coronavirus disease 19 infection, Viral pneumonia corticosteroid therapy alone, systematic antibiotic therapy alone, Variable regimens including azithromycin , baricitinib , hydroxychloroquine , lopinavir + ritonavir , sarilumab , tocilizumab HIV protease inhibitor, IL-6 receptor antagonist, Jak1 tyrosine kinase inhibitor, Jak2 tyrosine kinase inhibitor Centre Hospitalier Intercommunal Robert Ballanger Groupe Hospitalier Pitie-Salpetriere France 2020-03-14 2020-07-31 GHTRB-2020-01, NCT04366206 Phase Not Applicable Recruiting 2 4 Months 143 Benjamin Rossi, MD, Dr. Hélène GROS, Hélène Gros, MD, Lee S Nguyen, MD, PhDc 2020-04-30
Evaluating AVM-0703 for Treatment of COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome AVM-0703 plus hydrocortisone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) AVM Biotechnology LLC Medpace Inc 2020-06-30 2023-06-30 AVM0703-101, NCT04366115 Phase 1/Phase 2 Clinical Not yet recruiting 0 36 Months 126 Brandon Franklin 2020-04-30
Effect of Treatments in Patients Hospitalized for Severe COVID-19 Pneumonia: a Multicenter, Cohort Study Coronavirus disease 19 infection, Viral pneumonia azithromycin alone, baricitinib alone, hydroxychloroquine alone, lopinavir + ritonavir alone, oseltamivir alone, remdesivir alone, sarilumab alone, tocilizumab alone Coronavirus non structural protein 8 modulator, Exo-alpha sialidase inhibitor, HIV protease inhibitor, IL-6 receptor antagonist, Jak1 tyrosine kinase inhibitor, Jak2 tyrosine kinase inhibitor, RNA polymerase modulator Groupe Hospitalier Pitie-Salpetriere CMC Ambroise Paré, Centre Hospitalier Intercommunal Montfermeil-Le Raincy, Centre Hospitalier Intercommunal Robert Ballanger France 2020-03-14 2020-12-31 CIC1421-20-06, NCT04365764 Phase Not Applicable Recruiting 2 9 Months 400 Anis Saib, MD, Hélène Gros, MD, Joe-Elie Salem, MD, PhD, Lee S Nguyen 2020-04-30
COV-CREM: Study of Specific Viral Immune Responses Induced by SARS-CoV-2 (COVID-19) Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital of Besancon France 2020-04-20 2025-04-20 2020/502, COV-CREM, NCT04365322 Phase Not Applicable Recruiting 1 60 Months 60 Kevin BOUILLER, MD, Marie KROEMER, PharmD PhD 2020-04-30
CBP-COVID: Impact of SARS-COV2 Infection and Confinement on Diagnostic and Therapeutic Management of Lung Cancer: Ambispective Study Extended Over Two Time Periods Coronavirus disease 19 infection, Lung tumor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier le Mans ONCOPL (FR) 2020-06-30 2022-08-28 CBP-COVID, CHM-2020/S15/03, NCT04366219 Phase Not Applicable Not yet recruiting 0 25 Months 2000 CHRISTELLE JADEAU, OLIVIER MOLINIER, MD 2020-04-30
A larger phase IIb/III trial of recombinant subunit-trimer vaccine (COVID-19), Clover Biopharmaceuticals for the potential prevention of coronavirus infection COVID-19 caused by SARS-CoV-2 (2019-nCoV) Coronavirus disease 19 infection recombinant subunit-trimer vaccine (COVID-19), Clover Biopharmaceuticals alone Angiotensin converting enzyme 2 modulator Linear Clinical Research Limited Australia Phase 2/Phase 3 Clinical Planned 1 2020-04-30
The Psychological Impact of COVID-19 Outbreak on COVID-19 Survivors and Their Families Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The University of Hong Kong Queen Mary Hospital Hong Kong 2020-04-27 2021-06-30 NCT04365348, UW20-300 Phase Not Applicable Not yet recruiting 1 14 Months 300 Agnes YK Lai, PhD, Mary SM Ip, MD 2020-04-30
A phase I clinical trial of recombinant subunit-trimer vaccine (COVID-19) in healthy adult and healthy elderly trial participants Coronavirus disease 19 infection recombinant subunit-trimer vaccine (COVID-19), Clover Biopharmaceuticals alone Angiotensin converting enzyme 2 modulator Healthy volunteers accepted Clover Biopharmaceuticals AUS Pty Ltd, Coalition for Epidemic Preparedness Innovations, Linear Clinical Research Limited Australia 2020-06-30 Phase 1 Clinical Planned 1 2020-05-04
COVIPACT: Impact of the COVID-19 Infectious Epidemic on the Management of Oncology and Onco-hematology Patients and on the Psychological Consequences for Patients and Caregivers Acute stress disorder, Cognitive disorder, Coronavirus disease 19 infection, Hematological neoplasm, Post traumatic stress disorder, Sleep disorder, Solid tumor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Francois Baclesse France 2020-04-15 2020-12-31 2020-A00879-30, COVIPACT, NCT04366154 Phase Not Applicable Recruiting 1 8 Months 385 Audrey FAVEYRIAL, MD, Florence JOLY, PhD 2020-05-01
OUTCOV: Outpatient Treatment of COVID-19 in Patients With Risk Factor for Poor Outcome Bordetella pertussis infection, Coronavirus disease 19 infection, Dyspnea azithromycin alone, hydroxychlororquine alone, lopinavir + ritonavir alone HIV protease inhibitor Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Groupe Hospitalier Paris Saint-Joseph France 2020-04-28 2021-01-28 NCT04365582, OUTCOV, OUTCOV Phase 3 Clinical Not yet recruiting 5 9 Months 640 Christos CHOUAID, MD, Helene Beaussier, MD PhD, Hilario Nunes, MD, Jean Marc NACCACHE, MD, Jean-Marc Naccache, MD, Pierre CHARLES, MD 2020-04-30
Evaluation of the Probiotic Lactobacillus Coryniformis K8 on COVID-19 Prevention in Healthcare Workers Coronavirus disease 19 infection Lactobacillus coryniformis K8 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Puleva Biotech SA Spain 2020-04-24 2020-10-31 NCT04366180, P054 Phase Not Applicable Recruiting 1 6 Months 314 Raquel Rodriguez Blanque 2020-05-01
COVIDGHPSJCite: Become of Patients Infected or Suspected of Being Infected by Covid-19 and Supported by the GHPSJ and the Establishments of the Paris Plaisance Hospital City Coronavirus disease 19 infection Groupe Hospitalier Paris Saint-Joseph France 2020-04-01 2022-12-31 COHORTE COVID GHPSJ CITEH, COVIDGHPSJCite, NCT04365530 Phase Not Applicable Recruiting 5 33 Months 2000 Benoit PILMIS, MD, Bernard DURAND GASSELIN, MD, Bernard Durand Gasselin, MD, Florence Bonte, MD, Helene BEAUSSIER, PharmD, pHD, Maxime TOUZOT, MD, Sebastien HASCOET, MD, Sebastien Hascoet, MD 2020-05-03
Canakinumab to Reduce Deterioration of Cardiac and Respiratory Function Due to COVID-19 Coronavirus disease 19 infection, Heart injury, Inflammatory disease, Respiratory failure canakinumab alone Immunoglobulin G1 agonist, Interleukin-1 beta ligand inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cleveland Clinic Foundation US 2020-04-24 2020-12-31 IND 149328, NCT04365153 Phase 2 Clinical Recruiting 0 8 Months 45 Calvin Sheng, M. D., Ossama Abou Hassan, M. D., Paul C Cremer, M. D., Sidhharth Dugar, M. D., Tom Wang, M. D., Venu Menon, M. D., Yuki Kuramochci, RN BSN, Yuki Kuramochi, RN BSN 2020-05-04
CardiacCovid: Patient Recovery From Heart Surgery During the Covid-19 Pandemic Cardiac surgical procedure, Coronavirus disease 19 infection, Depression Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Barts and The London NHS Trust Queen Mary University of London UK 2020-04-18 2021-12-31 132127, CardiacCovid, NCT04366167 Phase Not Applicable Recruiting 1 20 Months 100 Aung Ye Oo, MD, Julie Sanders, PhD, Teofila Bueser, MSc 2020-05-06
A Novel Nomogram to Predict Severity of COVID-19 Coronavirus disease 19 infection RT-PCR test alone, computed tomography imaging alone, novel nomogram model prediction alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Xinqiao Hospital of Chongqing China 2020-01-17 2021-12-31 NCT04366024, XQONC-016 Phase Not Applicable Recruiting 1 23 Months 1000 Jianguo Sun, Sun Jianguo 2020-05-06
A phase II, randomized, double-blind, placebo-controlled study to evaluate the safety and efficacy of OT-101 in adult patients hospitalized with COVID-19 and pneumonia Coronavirus disease 19 infection, Viral pneumonia OT-101 alone Factor IX agonist Mateon Therapeutics Inc US Phase 2 Clinical Planned 0 2020-04-29
PRE-VENT: A phase III, randomized, double-blind, placebo-controlled, multicenter study to evaluate the safety and efficacy of pacritinib plus standard of care versus placebo plus standard of care in hospitalized patients with severe COVID-19, including patients with and without cancer Coronavirus disease 19 infection pacritinib alone, standard of care alone CSF-1 antagonist, Cytochrome P450 reductase inhibitor, Flt3 tyrosine kinase inhibitor, IRAK-1 protein kinase inhibitor, Jak2 tyrosine kinase inhibitor CTI BioPharma Corp US 2020-04-27 PRE-VENT Phase 3 Clinical Not yet recruiting 0 358 John Mascarenhas 2020-04-29
REACOVIM: Study of Clinical and Immune Severity Profiles of Patients Infected With SARS-Cov2 (COVID-19) Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Direction Centrale du Service de Sante des Armees France 2020-04-20 2022-04-20 2020-COVID19-05, NCT04365166, REACOVIM Phase Not Applicable Recruiting 2 24 Months 100 Clément DUBOST, MD, PhD, Nicolas LIBERT, MD, PhD 2020-05-04
Cardiovascular Effects of COVID-19 Cardiovascular disease, Coronavirus disease 19 infection fluoxetine (Zydis, tablet, autism), Autism Therapeutics alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) NYU Langone Health US 2020-04-08 2020-12-31 20-00416, NCT04365699 Phase 2 Clinical Recruiting 0 8 Months 500 Stuart Katz, MD 2020-05-04
PIIPPI: COVID-19: Povidone-Iodine Intranasal Prophylaxis in Front-line Healthcare Personnel and Inpatients Coronavirus disease 19 infection Standard PPE alone, Standard care alone, povidone-iodine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Kentucky US 2020-05-31 2021-05-31 58748, NCT04364802, PIIPPI Phase 2 Clinical Not yet recruiting 0 12 Months 250 Alexandra E Kejner, MD, James Porterfield, MD, PhD, Melissa Thompson-Bastin, PharmD, Nikita Gupta, MD, Nikta Gupta, MD 2020-05-04
PEAC: Protective Effect of Aspirin on COVID-19 Patients Coronavirus disease 19 infection, Viral pneumonia aspirin alone, combined standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Xijing Hospital China 2020-02-10 2020-06-30 NCT04365309, PEAC, XI JINGH Phase 2/Phase 3 Clinical Recruiting 1 4 Months 128 Cai Yue 2020-04-30
The Psychological Impact of the COVID-19 on Students Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The University of Hong Kong Hong Kong 2020-04-26 2021-03-31 NCT04365361, UW20-298 Phase Not Applicable Not yet recruiting 1 11 Months 300 Agnes YK Lai, PhD, Kelvin MP Wang, PhD, LAI YK Agnes, PhD 2020-04-30
A phase III trial to evaluate NT-300 for the early treatment of COVID-19 and other viral respiratory illnesses Coronavirus disease 19 infection, Viral respiratory tract infection nitazoxanide (controlled-release, viral infections), Romark alone Romark Laboratories LC Phase 3 Clinical Planned 0 2020-04-29
Validation of new detection methods for SARS CoV-2 in suspected COVID-19 Coronavirus disease 19 infection Naso-pharyngeal swab testing alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Constance Deutsche Forschungsgemeinschaft (DFG), German Federal Ministry of Education and Research Germany 2020-04-24 DRKS00021578, Eilentscheid 05/2020, U0351-4483-4510 Phase 1 Clinical Recruiting 1 300 Christof Hauck, Marcus Schuchmann 2020-05-01
A clinical study of POL-6014 in the treatment of patients with COVID-related acute respiratory distress syndrome Coronavirus disease 19 infection, Respiratory distress syndrome lonodelestat alone Leukocyte elastase inhibitor Santhera Pharmaceuticals AG Cold Spring Harbor Laboratory Phase Not Applicable Planned 0 2020-04-29
PREVENT-COVID Trial: Prazosin to Prevent COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory tract infection once daily prazosin (OROS), ALZA alone Alpha 1A adrenoceptor antagonist, Cyclic nucleotide phosphodiesterase inhibitor Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Johns Hopkins University US 2020-04-30 2020-12-31 COV2001, IRB00246659, NCT04365257, PREVENT-COVID Trial Phase 2 Clinical Not yet recruiting 0 8 Months 220 Chetan Bettegowda, MD/PhD 2020-04-30
Mon-Covid: Home Care for Patients With COVID-19: Active Monitoring in Two Italian Health Units (Casale Monferrato and Torino) Coronavirus disease 19 infection home care monitoring alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mario Negri Gynecologic Oncology group Italy 2020-04-21 2020-12-31 MON-COVID, Mon-Covid, NCT04361916 Phase Not Applicable Recruiting 1 8 Months 425 Chiara Gerardi, PhD, Guido Bertolini, MD, Rita Banzi, PhD, Roberto Stura 2020-04-30
Use of Contemporary Live Tele-Video Conferencing for Continuing Surgical Training at the time of COVID-19 pandemic Coronavirus disease 19 infection Sultanah Aminah Hospital Malaysia 2020-05-01 2020-05-31 NMRR-20-814-54742 Phase Not Applicable Status not specified 1 1 Month dr henry tan chor lip 2020-04-30
Clinical Trial to Assess the Safety and Efficacy of Intravenous Administration of Allogeneic Adult Mesenchymal Stem Cells of Expanded Adipose Tissue in Patients With Severe Pneumonia Due to COVID-19 Coronavirus disease 19 infection, Viral pneumonia allogeneic and expanded adipose tissue-derived mesenchymal stem cells alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Andalusian Network for Design and Translation of Advanced Therapies Junta De Andalucia Spain 2020-04-30 2021-10-31 2020-001364-29, ADIQURE/COVID-19, NCT04366323 Phase 1/Phase 2 Clinical Not yet recruiting 1 18 Months 26 Ana Cardesa Gil, Clinical Trial Unit 2020-04-30
Stress Level Among Healthcare Workers in Handling COVID-19 Patients in Sarawak General Hospital Coronavirus disease 19 infection Universiti Malaysia Sarawak Malaysia 2020-05-04 2020-10-30 54744, NMRR-20-819-54744 Phase Not Applicable Not yet recruiting 1 5 Months Dr. Sim Sze Kiat 2020-04-30
CancerMCO: CancerMCO Coronavirus disease 19 infection Universiti Putra Malaysia Malaysia 2020-05-01 2020-11-01 54786, CancerMCO, NMRR-20-825-54786 Phase Not Applicable Not yet recruiting 1 6 Months Dr Sri Ganesh Muthiah 2020-04-30
CT-COVID-AI: CT-COVID-AI Coronavirus disease 19 infection Chest CT Diagnosis alone Hospital Sungai Buloh Malaysia 2020-05-01 2020-11-02 54784, CT-COVID-AI, NMRR-20-826-54784 Phase Not Applicable Not yet recruiting 1 6 Months Dr Mohan Dass Pathmanathan 2020-04-30
Effectiveness and Safety of Medical Treatment for SARS-CoV-2 (COVID-19) in Colombia Coronavirus disease 19 infection Standard treatment alone, hydroxychloroquine alone, Variable regimens including azithromycin , hydroxychloroquine , lopinavir + ritonavir HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National University of Colombia Fundación Cardioinfantil-Instituto De Cardiología, Hospital Universitario Reina Sofia, Hospital Universitario San Ignacio, Hospital Universitario de Neiva, Javeriana University Colombia 2020-05-11 2020-10-31 76968, NCT04359095 Phase 2/Phase 3 Clinical Not yet recruiting 6 5 Months 1600 Angel García-Peña, MD, Carlos A Alvarez-Moreno, MD, MSc, PhD, Dagoberto Santofimio-Sierra, MD, Hernando G Gaitán-Duarte, MD, MSc, Hernando Gaitán, MD, Jose G Ruiz-Rodriguez, MD, Juan Villar-Centeno, Nancy Yomayusa-Gonzalez, MD 2020-05-01
Needle Stick Injuries in Emergency Medical Service Practice Coronavirus disease 19 infection Cardiopulmonary resuscitation alone, double gloves alone Lazarski University Medical University of Bialystok, Poznan University of Medical Sciences Poland 2020-02-28 2020-04-24 NCT04363788, OH_PPE_1 Phase Not Applicable Completed 1 1 Month 300 2020-04-30
DISTANSE COVID: Direct Income SupporT and Advice Negating Spread of Epidemic COVID-19: a Randomized, Controlled Trial Coronavirus disease 19 infection Cash transfer alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) St Michaels Hospital Canada 2020-04-20 2021-06-30 20-081, DISTANSE COVID, NCT04359264 Phase Not Applicable Not yet recruiting 2 14 Months 392 Mike Bedard, Mike Bedard, MD, Nav Persaud, Nav Persaud, MD, MSc 2020-04-30
Adapting the Decathlon Group Easybreathe snorkelling face mask for the safer administration of oxygen and/or continuous positive airway pressure and in the intra/interhospital transportation of patients with proven or suspected COVID 19 infection Coronavirus disease 19 infection Easybreathe snorkelling face mask alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Monash Health Australia 2020-04-27 2020-10-27 ACTRN12620000472976p Phase Not Applicable Not yet recruiting 1 6 Months 100 Dr Simon Joosten 2020-05-01
COVID-19 Recovered Volunteer Research Participant Pool Registry Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of California Los Angeles US 2020-04-08 2042-04-20 20-000625, NCT04359602 Phase Not Applicable Recruiting 0 264 Months 10000 Antonia Petruse, MBA, Arash Naeim, MD, PhD 2020-05-05
Different PEEP Settings of COVID-19 Induced ARDS Coronavirus disease 19 infection, Respiratory distress syndrome ARDSnet table PEEP setting alone, Optimizing compliance alone, Optimizing oxygenation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Southeast University China 2020-03-05 2020-03-25 COVID-19 PEEP TITRATION, NCT04359251 Phase Not Applicable Completed 1 20 Chun C Pan, Chun Pan 2020-04-30
STRIPE-3: Study for Testing and Reviewing Improvised PPE Effectiveness 3 Coronavirus disease 19 infection Anesthetic facemask based improvised personal protective equipment alone, Snorkel-based improvised personal protective equipment alone, light exercise alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Guy's & St Thomas' Hospital NHS Trust UK 2020-04-28 2020-10-28 NCT04362163, STRIPE-3, TAP_PRG_21_04_2020_2 Phase Not Applicable Not yet recruiting 1 6 Months 10 Paul R Greig, MBChB 2020-05-01
REST: Online Cognitive Behavioral Therapy (CBT) for Stress Disorders in Health Workers Involved in the Care of Patients During the Covid-19 Epidemic Acute stress disorder, Coronavirus disease 19 infection Online cognitive behavioral therapy (CBT) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University Hospital of Strasbourg 2020-05-01 2021-10-01 7799, NCT04362358, REST Phase Not Applicable Not yet recruiting 0 17 Months 120 Luisa Weiner, MD 2020-04-30
TVP-COVID-RIV: Influence of COVID-19 Infection in Thromboembolic Venous Disease: National Cohort Study Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sociedad Espanola de Angiologia y Cirugia Vascular Spain 2020-04-30 2020-12-31 NCT04361981, RIV-R3, TVP-COVID-RIV Phase Not Applicable Not yet recruiting 1 8 Months 50 Joaquin De Haro, MD 2020-04-30
Liver Injury in Patients With COVID-19 Coronavirus disease 19 infection, Liver injury Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidad Austral De Argentina Argentina 2020-04-15 2020-12-31 CIE N° P 20-011, NCT04358380 Phase Not Applicable Recruiting 1 8 Months 34 Marcelo O Silva, MD 2020-04-30
DAWN AZITHRO: COVID-19: A randomized, open-label, adaptive, proof-of-concept clinical trial of new antiviral drug candidates against SARS-CoV-2 Coronavirus disease 19 infection azithromycin alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) UZ Leuven-University Hospitals Belgium 2020-04-22 2020-001614-38, DAWN AZITHRO, S63935 Phase 2 Clinical Recruiting 1 240 Clinical trial center UZ Leuven, clinical trial center UZ Leuven 2020-04-30
COVID19 HTAA: COVID19 HTAA Coronavirus disease 19 infection Hospital Tengku Ampuan Afzan Malaysia 2020-04-25 2020-07-31 54513, COVID19 HTAA, NMRR-20-811-54513 Phase Not Applicable Status not specified 1 3 Months 90 Dr SOH TZE VEE 2020-04-30
The epidemiology of COVID-19 cases and disease surveillance system in Hulu Langat district, Selangor Coronavirus disease 19 infection Pejabat Kesihatan Daerah Hulu Langat Malaysia 2020-04-24 2021-04-23 54757, NMRR-20-809-54757 Phase Not Applicable Status not specified 1 12 Months Dr WAN MING KEONG 2020-04-30
MLCOVID: MLCOVID Coronavirus disease 19 infection Machine Learning alone Institute For Medical Research (Inc In Malaysia) Malaysia 2020-04-24 2021-04-23 54483, COVID19-HSB/2, MLCOVID, NMRR-20-807-54483 Phase Not Applicable Status not specified 1 12 Months Dr Suresh Kumar, Dr WONG XIN CI 2020-04-30
QTc COVID: QTc COVID Coronavirus disease 19 infection Hospital Sungai Buloh Malaysia 2020-04-30 2020-05-30 54728, NMRR-20-798-54728, QTc COVID Phase Not Applicable Status not specified 1 1 Month Ms KOH HUI MOON 2020-04-30
IP COVID-19: IP COVID-19 Coronavirus disease 19 infection National Institutes of Health Malaysia Malaysia 2020-04-30 2020-09-30 54770, IP COVID-19, NMRR-20-793-54770 Phase Not Applicable Status not specified 1 5 Months Dr. Ainul Nadziha bt. Mohd. Hanafiah, Roslinda binti Abu Sapian 2020-04-30
Study of FT-516 for the Treatment of COVID-19 in Hospitalized Patients With Hypoxia Coronavirus disease 19 infection, Hypoxia FT-516 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Masonic Cancer Center US 2020-05-04 2022-01-31 IDIM-2020-28708, NCT04363346 Phase 1 Clinical Not yet recruiting 0 20 Months 12 Dr.Joshua Rhein, MD, Mahsa Abassi, DO,MPH, Meghan Rothenberger, MD, Timothy Schacker, MD 2020-05-01
COVID AMBU 60: Multicenter, Observational Study on Management COVID-19 Positive Outpatients in a French Cluster Coronavirus disease 19 infection observational management alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Maison de Sante Pluridisciplinaire de Creil France 2020-03-01 2020-12-31 2020-A01059-30, COVID AMBU 60, NCT04363099 Phase Not Applicable Recruiting 1 10 Months 1000 DIMI Svetlane, Svetlane DIMI, Svetlane DIMI, M.D 2020-04-30
COVID-EC Study: Clinical Characteristics of Patients With COVID-19 in Guayaquil, Ecuador Coronavirus disease 19 infection, Respiratory tract infection azithromycin alone, chloroquine alone, corticosteroids alone, enoxaparin alone, heparin alone, hydroxychloroquine alone, ivermectin alone, lopinavir + ritonavir alone, nitazoxanide alone, oseltamivir alone, tocilizumab alone Chloride channel modulator, Exo-alpha sialidase inhibitor, HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Clinico San Carlos Universidad Catolica Santiago de Guayaquil Spain 2020-04-30 2020-05-31 001, COVID-EC Study, NCT04362969 Phase Not Applicable Not yet recruiting 1 1 Month 300 Jorge Carriel M. 2020-05-01
Collection of Biological Samples With Clinical Characterization of Covid-19 Patients Coronavirus disease 19 infection blood sampling alone Centre Hospitalier Intercommunal Creteil France 2020-05-01 2020-12-01 COVIGENET, NCT04363385 Phase Not Applicable Not yet recruiting 1 7 Months 500 Bernard MAITRE, Ph D, Bernard Maitre, Ph D, Isabelle HAU, MD 2020-04-29
Rhu-pGSN for Severe Covid-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia gelsolin, BioAegis Therapeutics alone Actin antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) BioAegis Therapeutics Inc 2020-06-30 2020-09-30 BTI-202, NCT04358406 Phase 2 Clinical Not yet recruiting 0 3 Months 60 Mark J DiNubile, MD, Susan L Levinson, PhD 2020-05-01
CEDiD: COVID-19 Early Diagnosis in Doctors Coronavirus disease 19 infection Empatica E4 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) King's College London Empatica Srl UK 2020-04-27 2020-05-27 CEDID STUDY STH, CEDiD, NCT04363489 Phase Not Applicable Not yet recruiting 1 1 Month 30 Alexander Zargaran, Anne Greenough, Dina Radenkovic, Dina Radenkovic, MBBS, BSc, Dr Alexander Zargaran 2020-04-29
Levamisole and Isoprinosine in Immune-prophylaxis of Egyptian Healthcare Workers Facing COVID-19 Coronavirus disease 19 infection isoprinosine alone, levamisole alone, isoprinosine plus levamisole Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ain Shams University Egypt 2020-05-20 2020-12-01 FMASU P20A/ 2020, NCT04360122 Phase 3 Clinical Not yet recruiting 1 6 Months 100 Fatma Soliman E Ebeid, Mariam Amin, MD 2020-05-06
The Effects of Pulmonary Physiotherapy Treatments on Patients With COVID-19 Coronavirus disease 19 infection, Viral pneumonia pulmonary physiotherapy techniques alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Tehran University of Medical Sciences Iran 2020-04-20 2020-08-01 99-1-103-47429, NCT04357340 Phase Not Applicable Not yet recruiting 1 3 Months 40 Behrouz Attarbashi Moghaddam, Ph.D., Mohammad Javaherian, Ph.D. cand., Seyyed Reza Raees Karami, MD., Zahra Ahmadinejad, MD. 2020-04-30
CovImmune: Study of Immune Response During SARS-CoV-2 Infection - (COVID-19) Coronavirus disease 19 infection blood sampling alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire De Nice France 2020-04-22 2020-10-22 20-PP-05, CovImmune, NCT04355351 Phase Not Applicable Not yet recruiting 3 6 Months 400 Barbara SEITZ-POLSKI, MCUPH, Jean DELLAMONICA, PUPH, Matteo VASSALLO, PH, elisa DEMONCHY, PH, johanna PLANCHARD, PH, sonia BOYER-SUAVET, PH 2020-04-30
Convalescent Plasma Trial in COVID-19 Patients Coronavirus disease 19 infection, Hypoxia, Viral pneumonia convalescent plasma alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Royal College of Surgeons in Ireland - Medical University of Bahrain Bahrain Defence Force Royal Medical Services, Military Hospital, Salmaniya Medical Complex Bahrain 2020-04-19 2020-06-30 BDF/R&REC/2020-423, NCT04356534 Phase 2 Clinical Not yet recruiting 1 2 Months 40 Abdulkarim Abdulrahman, Dr., Abdulrahman Almadani, Dr., Amal Hejab, Dr., Manaf Al Qahtani, Dr., Manal Al Sayed, Dr., Pearl Wasif, MSc., Salman Yousif Alali, Dr., Sameer Otoom, Prof., Stephen Atkin, Prof. 2020-04-30
Nancy-CovH-AKI: Cardiovascular and Renal Biomarkers to Predict Acute Heart or Kidney Injury in Severe COVID-19 Infection Coronavirus disease 19 infection, Heart injury, Renal injury clinical examination alone, telephone follow-up alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Hospital, Nancy, France France 2020-04-27 2020-10-18 2020PI072, NCT04354610, Nancy-CovH-AKI Phase Not Applicable Recruiting 1 5 Months 57 Antoine KIMMOUN, MD, PhD, Patrick ROSSIGNOL, MD, PhD 2020-05-04
FatCovid-19: Chronic Fatigue Etiology and Recovery in Covid-19 Patients: the Role of Fatigability Chronic fatigue syndrome, Coronavirus disease 19 infection actigraphy alone, blood test alone, electromyography alone, ergometer alone, magnetic resonance imaging alone, maximal effort test alone, neuromuscular evaluation alone, peripheral nerve stimulation alone, transcranial magnetic stimulation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Centre Hospitalier Universitaire de Saint Etienne Universite Jean Monnet France 2020-04-30 2021-12-31 2020-A00982-37, 20CH085, FatCovid-19, NCT04363606 Phase Not Applicable Not yet recruiting 3 20 Months 52 Guillaume THIERY, MD PhD, Jérome MOREL, MD PhD, Jérôme MOREL, MD PhD, Laurent GERGELE, MD, Lydia OUJAMAA, MD, Léonard FEASSON, MD PhD, Pascal GIRAUX, MD, Pierre CROISILLE, MD PhD 2020-04-29
MARIPOSA: A Study to Investigate Intravenous Tocilizumab in Participants With Moderate to Severe COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia standard of care alone, tocilizumab (intravenous), Roche/Chugai alone IL-6 receptor antagonist, IL-6 receptor modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Roche Holding AG 2020-05-04 2020-08-03 CA42481, MARIPOSA, NCT04363736 Phase 2 Clinical Not yet recruiting 0 3 Months 100 Clinical Trials 2020-04-29
COVIDeF: Cohort of Patients Infected With SARS-CoV2 (COVID-19) or Suspected of Being Coronavirus disease 19 infection Variable regimens including blood sampling Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-03-31 2022-03-31 2020-A00754-35, APHP200382, COVIDeF, NCT04352348 Phase Not Applicable Recruiting 1 24 Months 2000 Linda Gimeno, Pierre HAUSFATER, MD, Pierre Hausfater, MD 2020-04-30
COMBAT-COVID19: Colchicine in Moderate Severity Hospitalized Patients Before ARDS to Treat COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome colchicine alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Maimonides Medical Center US 2020-04-26 2021-06-30 2020-04-12, COMBAT-COVID19, NCT04363437 Phase 2 Clinical Recruiting 0 14 Months 70 Antonios Likourezos, MA, MPH, Antonios Likourezos, MPH, Felix Yang, MD 2020-05-01
Early Identification and Treatment of Cytokine Storm Syndrome in Covid-19 Coronavirus disease 19 infection, Respiratory failure anakinra alone Type I IL-1 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Alabama at Birmingham US 2020-05-31 2020-12-31 CHATHAM-CYTOKINE COVID-19, NCT04362111 Phase 3 Clinical Not yet recruiting 0 7 Months 20 Angela Kendrach, Walter W Chatham, MD 2020-04-29
GETAFE: Low-dose Lenalidomide for Non-severe COVID-19 Treatment Trial Coronavirus disease 19 infection lenalidomide plus low molecular weight heparin (LMWH) Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Universitario de Getafe Spain 2020-04-27 2020-12-31 COVID19-EC01, GETAFE, NCT04361643 Phase 4 Clinical Not yet recruiting 2 8 Months 120 Joaquin De Haro, MD, Joaquin De Haro, MD, PhD, Joaquin De Haro, MD,PhD 2020-05-04
Tocilizumab Treatment in Patients With COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome tocilizumab (intravenous), Roche/Chugai alone IL-6 receptor antagonist, IL-6 receptor modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto Nacional de Cancerologia de Mexico Roche Pharma (Schweiz) AG Mexico 2020-04-01 2020-08-01 INF-3343-20-22-1, NCT04363853 Phase 2 Clinical Recruiting 1 4 Months 200 Diana Flores Estrada, Oscar G Arrieta, MD M Sc., Oscar G Arrieta, Oncologist, Oscar Gerardo Arrieta Rodríguez 2020-05-04
The Effects of Standard Protocol With or Without Colchicine in Covid-19 Infection Coronavirus disease 19 infection Variable regimens including azithromycin , ceftriaxone , colchicine , lopinavir + ritonavir , omega-3 , selenium , tiamine , vitamin A , vitamin C , vitamin D HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shaheed Beheshti Medical University Iran 2020-03-20 2020-05-30 NCT04360980, SBMU.IR.REC.165423 Phase 2 Clinical Recruiting 2 2 Months 80 CKDRC,SBMU, MD, Nooshin Dalili, Dr, Nooshin Dalili, MD, SBMU, nooshin dalili 2020-05-04
COVID 19 Biomarkers Coronavirus disease 19 infection, Respiratory distress syndrome University of British Columbia Canada 2020-03-30 2021-09-30 H20-00971, NCT04363008 Phase Not Applicable Recruiting 4 18 Months 150 Cheryl Wellington, PhD, Mypinder Sekhon, Mypinder Sekhon, MD 2020-05-04
The Impact of COVID-19 Pandemic on the Smoking Behavior of Young Smokers and the Youth Quitline Service in Hong Kong Coronavirus disease 19 infection, Nicotine dependence Telephone survey alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) The University of Hong Kong Hong Kong 2020-04-24 2020-06-30 NCT02758028_1, NCT04360863 Phase Not Applicable Recruiting 1 2 Months 150 Ho Cheung William Li, PhD, Long Kwan Ho, MPhil 2020-05-04
Psychological Impact of Corona Virus Among Doctors in Assiut University Hospitals Acute stress disorder, Coronavirus disease 19 infection, Psychiatric disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assiut University Egypt 2020-05-31 2021-06-30 NCT04363229, PSHYCOLOGICAL IMPACT OF CORONA Phase Not Applicable Not yet recruiting 1 13 Months 250 Mariam Roshdy Elkhayat, mariam elkhayat, MD, shimaa abdelsameaa, MD 2020-04-29
Clinical Impact of Bactek-R in Subject With Mild Pneumonia Due to COVID-19 Infection Coronavirus disease 19 infection, Viral pneumonia MV-130 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Inmunotek SL BioClever 2005 SL 2020-05-10 2020-07-31 MV130-SLG-35, NCT04363814 Phase 3 Clinical Not yet recruiting 0 2 Months 100 Guillermo Ángeles, Guillermo Ángeles, MD, M. Polanco, Martín Martín, MD, Miguel Casanovas, PhD, MD, Natalia García, Nicolas Batlle, MD, Raymundo Hernández 2020-05-04
ANACONDA: Anakinra for COVID-19 Respiratory Symptoms Coronavirus disease 19 infection, Respiratory disease anakinra alone, optimized standard of care alone Type I IL-1 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Tours INSERM CIC-P 1415, Swedish Orphan Biovitrum AB 2020-04-27 2020-09-24 2020-001734-36, ANACONDA, ANACONDA-COVID-19, DR200111, NCT04364009 Phase 3 Clinical Not yet recruiting 0 4 Months 240 Alexandra AUDEMARD-VERGER, MD-PhD, Elodie MOUSSET 2020-04-29
A multicenter, randomized, double-blind, placebo-controlled, proof-of-concept, phase II trial of Metablok for lung and kidney inflammation in patients with COVID-19 Coronavirus disease 19 infection, Lung inflammation, Nephritis Metablok alone Dehydropeptidase-1 modulator Arch Biopartners Inc Phase 2 Clinical Planned 0 2020-04-28
LEAD COVID-19: The LEAD COVID-19 Trial: Low-risk, Early Aspirin and Vitamin D to Reduce COVID-19 Hospitalizations Blood clotting disorder, Coronavirus disease 19 infection, Vitamin D deficiency aspirin alone, aspirin plus vitamin D Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Louisiana State University Health Sciences Center New Orleans US 2020-05-31 2020-12-31 20-063, LEAD COVID-19, NCT04363840 Phase 2 Clinical Not yet recruiting 0 7 Months 1080 Frank H Lau, MD 2020-04-29
Alterations in inflammatory and coagulation variables in COVID-19 patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Munich Germany 2020-04-27 20-296, DRKS00021581 Phase Not Applicable Recruiting 1 100 Tobias Nitschke 2020-04-29
AziA: Azithromycin + Amoxicillin/clavulanate versus Amoxicillin/clavulanate in COVID-19 Patients With Pneumonia in Non-intensive Unit Coronavirus disease 19 infection, Viral pneumonia Variable regimens including amoxicillin + clavulanate , azithromycin , cephalosporin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) CHU De Nantes France 2020-04-30 2020-07-30 AziA, NCT04363060, RC20_0168 Phase 3 Clinical Not yet recruiting 3 3 Months 104 Blandine RAMMAERT, MD, PhD, Emmanuel MONTASSIER, Romain DECOURS, MD, PhD, Vincent DUBEE, MD, PhD 2020-05-04
Sarilumab for Patients With Moderate COVID-19 Disease: A Randomized Controlled Trial With a Play-The-Winner Design Coronavirus disease 19 infection Variable regimens including hydroxychloroquine , remdesivir , sarilumab IL-6 receptor antagonist, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) VA Boston Healthcare System US 2020-04-10 2023-04-10 IRB 3305, NCT04359901 Phase 2 Clinical Recruiting 0 36 Months 120 Colleen Shannon, MPH, Patricia Woods, RN, MSN, Paul Monach, MD, Sara Schiller, MPH, Westyn Branch-Elliman, MD 2020-04-30
Identification of predictive biomarkers for severe progression of COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bundeswehrkrankenhaus Berlin Germany 2020-05-03 DRKS00021591, Eth-10/20 Phase Not Applicable Not yet recruiting 4 100 Christian Zobel, Maximilian Schreiner 2020-05-03
CytoResc: CytoSorb Rescue for COVID-19 Cytokine Storm Coronavirus disease 19 infection CytoSorb therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Charité Campus Virchow-Klinikum Germany 2020-05-01 CytoResc, DRKS00021447, EA1/069/20, U1111-1250-8875 Phase 2b Clinical Not yet recruiting 4 100 Philipp Enghardt, Torsten Slowinski 2020-04-30
Local Thermotherapy for Patients With Moderate Symptoms of COVID-19 Coronavirus disease 19 infection electric chest pad alone, electric cushion therapy alone, thermotherapy alone National Institute of Perinatology Directorate for Quality and Health Education, Juarez de Mexico Hospital, Laboratorios Silanes SA De CV Mexico 2020-04-30 2020-11-30 CONACYTF0005-2020-01S311971, NCT04363541, U1111-1250-7416 Phase Not Applicable Not yet recruiting 1 7 Months 298 Gabriela Ibañez Cervantes, PhD, Norma del Carmen Galindo Sevilla, PhD, Norma del Carmen Galindo-Sevilla 2020-04-30
ESCAPE: Evaluation of SARS-CoV-2 (COVID-19) Antibody-containing Plasma therapy Coronavirus disease 19 infection High-Titer COVID-19 Convalescent Plasma (HT-CCP) alone Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Brigham & Women's Hospital US 2020-04-30 2021-12-31 2020P001215, ESCAPE, NCT04361253 Phase 3 Clinical Not yet recruiting 0 20 Months 220 Karina Oganezova, Richard Kaufman, MD 2020-04-30
COVID.PPI: The influence of proton pump inhibitor therapy on the clinical course of COVID-19 Coronavirus disease 19 infection proton pump inhibitors therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Klinikum der Albert-Ludwigs Universitaet Freiburg Germany 2020-04-28 254/20, COVID.PPI, DRKS00021523 Phase Not Applicable Recruiting 1 200 Dominik Bettinger 2020-04-30
Impact of WeChat-based parenting education for children with autism spectrum disorder and their mothers during the epidemic of Coronavirus disease 2019 (COVID-19) Autism, Coronavirus disease 19 infection WeChat-based parenting education alone Preschool Children (2-5 yrs), Children (6-12 yrs) Fujian Maternity and Child Health Care Hospital China 2020-02-01 2020-10-31 ChiCTR2000031772 Phase 0 Clinical Recruiting 1 9 Months 105 Guihua Liu 2020-04-30
COVID-AGE: Clinical-epidemiological Characterization of COVID-19 Disease in Hospitalized Older Adults Coronavirus disease 19 infection glucocorticoids alone, Variable regimens including anakinra , azithromycin , baricitinib , ceftriaxone , emtricitabine + tenofovir , hydroxychloroquine , lopinavir + ritonavir HIV protease inhibitor, Jak1 tyrosine kinase inhibitor, Jak2 tyrosine kinase inhibitor, Type I IL-1 receptor antagonist Aged Adults (65-79 yrs), Elderly Adults (80 and over) Complejo Hospitalario Universitario de Albacete Spain 2020-04-20 2020-07-31 COVID-AGE, NCT04362943, PAS-BAR-2020-04 Phase 4 Clinical Recruiting 2 3 Months 576 Almudena Avendaño Céspedes, RN, PhD, Pedro Abizanda Soler, MD,PhD 2020-04-30
Use of the Interleukin-6 Inhibitor Clazakizumab in Patients With Life-threatening COVID-19 Infection Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure clazakizumab alone IL-6 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Johns Hopkins University US 2020-04-30 2020-07-31 IRB00247932, NCT04363502 Phase 2 Clinical Not yet recruiting 0 3 Months 30 Nada Alachkar, MD, Russell Wesson, MD 2020-04-30
PROTECT: Study With Hydroxychloroquine for Prevention and Early Phase Treatment of Coronavirus Disease (COVID-19) Coronavirus disease 19 infection hydroxychloroquine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Istituto Scientifico Romagnolo Per Lo Studio E La Cura Dei Tumori (IRST) SRL Universita di Bologna Italy 2020-05-31 2021-03-31 IRST100.47, NCT04363827, PROTECT Phase 2 Clinical Not yet recruiting 1 10 Months 2300 Giovanni Martinelli, Prof., Oriana Nanni, Pierluigi Viale, Prof. 2020-04-30
Study for Healthy Behavior, Psychological Analysis and Psychological Reconstruction Strategies of Students Population Keeping in Home Under the Pandemic of Novel Coronavirus Pneumonia (COVID-19) Coronavirus disease 19 infection, Psychiatric disorder Face-to-face consultation alone, Phone consultation alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Sun Yat-Sen University National Natural Science Foundation of China China 2020-03-18 2021-03-18 ChiCTR2000032095 Phase 0 Clinical Recruiting 1 12 Months 130 Peijia Liu 2020-04-30
The Danish Pre-HCQ COVID19 Dialysis Study: Hydroxychloroquine for prevention of COVID-19 in patients on chronic dialysis Coronavirus disease 19 infection Plaquenil alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rigshospitalet, Denmark Denmark 2020-04-15 2020-001257-51, The Danish Pre-HCQ COVID19 Dialysis Study Phase 3 Clinical Recruiting 1 568 Department of Nephrology 2132 2020-04-29
A pilot study in patients with SARS-CoV-2 infection Coronavirus disease 19 infection Hemogenyx Pharmaceuticals Ltd Phase Not Applicable Recruiting 0 2020-04-29
A Study for Efficacy and Safety of Live Biotherapeutic MRx-4DP0004 to Treat COVID-19 Coronavirus disease 19 infection MRx-0004 alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) 4D pharma plc UK 2020-05-31 2020-09-30 MRX-4DP0004-II-001, NCT04363372 Phase 2 Clinical Not yet recruiting 1 4 Months 90 Clinical Operations, Dinesh Saralaya, MBBS, MD, MRCP, FRCP 2020-04-30
Clinical Trial of Mycobacterium w in COVID-19 Positive Patients, Hospitalized But Not Critically Ill Coronavirus disease 19 infection Mycobacterium w alone, standard care therapy alone Interferon gamma receptor agonist, MAPK gene modulator, TLR-2 agonist, TLR-4 agonist, TLR-9 agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cadila Pharmaceuticals Ltd Council of Scientific and Industrial Research (India) 2020-04-30 2021-04-30 CRSC20006, NCT04358809 Phase 3 Clinical Not yet recruiting 0 12 Months 480 Anil Avhad, MBBS, Sanjay Patel, MBBS 2020-04-29
Pharmacological Ascorbic Acid as an Activator of Lymphocyte Signaling for COVID-19 Treatment Coronavirus disease 19 infection Ascor (McGuff Pharmaceuticals, Ltd) plus magnesium chloride Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Thomas Jefferson University US 2020-05-31 2021-05-31 JT#15681, NCT04363216 Phase 2 Clinical Not yet recruiting 0 12 Months 66 Dagan Coppock, M.D., Daniel Monti, M.D., Melissa McCarey, Michael W Foster, M.D. 2020-05-06
COroFet: Assessment of Obstetric, Fetal and Neonatal Risks and Vertical SARS-CoV-2 Transmission During COVID-19 Pandemic Coronavirus disease 19 infection RT-PCR alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire de Toulouse France 2020-04-17 2022-04-30 COroFet, NCT04360811, RC31/20/0123 Phase Not Applicable Recruiting 1 24 Months 3600 Charlotte Dubucs, MD, Marion Groussolles, MD 2020-04-30
HCQPreP: Hydroxychloroquine as Prophylaxis for COVID-19 in Healthcare Workers Coronavirus disease 19 infection hydroxychloroquine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Louisiana State University Health Sciences Center New Orleans Lafayette General Medical Center, University Of Louisiana At Lafayette US 2020-04-27 2020-08-03 HCQPreP, LSU NO HSC IRB 20-050, NCT04363450 Phase 3 Clinical Recruiting 0 3 Months 1700 Ann Chauffe, Ann D Chauffe, DO, MPH, Ann D. Chauffe, DO, MPH, Carl Sabottke, MD, Daniel Stout, MD, Daniel Stouts, MD, James B Falterman, MD, Nicholas Sells, MD, Rebecca B Lee, DO, MS, Rebecca B. Lee, DO, MS 2020-05-01
Comparison of VieScope versus Macintosh Laryngoscope for Intubation in Level Cpersonal Protective Equipment Conditions Coronavirus disease 19 infection, Edema Vie Scope laryngoscope alone, intubation alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Lazarski University Medical University of Bialystok, Poznan University of Medical Sciences, Wroclaw Medical University Poland 2020-01-20 2020-02-25 INT_PPE_2020_1, NCT04363775 Phase Not Applicable Completed 1 1 Month 35 Łukasz Szarpak 2020-04-29
ACCESS: ACCESS A Master Digital Surveillance Protocol for COVID-19 Coronavirus disease 19 infection mobile app (Medable Inc) alone, wearable sensor alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Medable Inc American Heart Association, Biointellisense Inc, Datavant, PWNHealth LLC US 2020-04-20 2031-10-01 ACCESS, NCT04363268, PRO00041635 Phase Not Applicable Recruiting 0 137 Months 1000000 Ingrid Oakley-Girvan, Ph.D., Ingrid Oakley-Girvan, PhD, Jena Daniels, B.S., Jena Daniels, BS, Michelle Longmire, M.D., Reem Yunis, Ph.D., Reem Yunis, PhD 2020-04-30
Effect of plasma of patients recovered from Covid-19 versus control group on treatment of Covid-19 Coronavirus disease 19 infection Variable regimens including chloroquine , lopinavir , plasma , ritonavir Cytochrome P450 3A4 inhibitor, HIV protease inhibitor, HIV-1 protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hamadan University of Medical Sciences Iran 2020-05-14 IR.UMSHA.REC.1399.037, IRCT20120215009014N353 Phase 2 Clinical Not yet recruiting 1 100 Dr. Ebrahim Jalili, Dr. Jalal Poorolajal, Dr. Saeid Bashirian, Samereh Ghelichkhani 2020-04-29
CAN-COVID: Study of Efficacy and Safety of Canakinumab Treatment for CRS in Participants With COVID-19-induced Pneumonia Coronavirus disease 19 infection, Viral pneumonia canakinumab alone, standard of care alone Immunoglobulin G1 agonist, Interleukin-1 beta ligand inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Novartis AG, Novartis Farmaceutica SA Spain 2020-04-30 2020-10-05 2020-001370-30, CACZ885D2310, CAN-COVID, NCT04362813 Phase 3 Clinical Recruiting 1 5 Months 450 Novartis Pharmaceuticals, Trial Monitoring Organization (TMo) 2020-04-29
Dose-Finding Study of Ivermectin in the Treatment of COVID-19 Coronavirus disease 19 infection ivermectin alone, standard regimen therapy alone Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Qazvin University Of Medical Sciences Iran 2020-05-04 IR.QUMS.REC.1399.017, IRCT20200408046987N1 Phase 3 Clinical Recruiting 2 100 Dr Abbas Allami, Dr. Aliakbar Karami, Nematollah Gheibi, dr. morteza shakhs niaee 2020-05-04
VA-REACH: VA Remote and Equitable Access to COVID-19 Healthcare Delivery Coronavirus disease 19 infection azithromycin alone, hydroxychloroquine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) San Francisco VA Health Care System US 2020-04-30 2021-08-31 20-30517, NCT04363203, VA-REACH Phase 4 Clinical Not yet recruiting 0 16 Months 600 Salomeh Keyhani, MD MPH, Staff Physician 2020-04-30
COVIDAM: An open-label, single-center, randomized, controlled trial to evaluate the effect of hydroxychloroquine on viral shedding in mild COVID-19 Coronavirus disease 19 infection hydroxychloroquine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Institute of Tropical Medicine Belgium 2020-04-12 2020-001417-21, COVIDAM, ITM202004 Phase 2 Clinical Recruiting 1 206 Yven Van Herrewege 2020-04-29
A first-in-human trial of recombinant adenoviral vector vaccine targeting SARS-CoV-2 spike protein for the treatment in patients with COVID-19 infection Coronavirus disease 19 infection recombinant adenoviral vector vaccine targeting SARS-CoV-2 spike protein (liquid formulation, COVID-19), ReiThera alone COVID19 Spike glycoprotein modulator ReiThera Srl Italy Phase Not Applicable Planned 1 2020-04-29
ONCOVID-19: Prospective Analysis of Morbi-mortality of Patients With Cancers in Active Phase of Treatment Suspected or Diagnosed of a SARS-CoV-2 Infection Coronavirus disease 19 infection, Hematological neoplasm, Solid tumor medical treatment alone Centre Leon Berard France 2020-04-02 2020-06-30 ET20-069, NCT04363632, ONCOVID-19 Phase Not Applicable Recruiting 18 2 Months 150 Anne-Laure Anne-Laure, Dr., Blaha BELGADI, Dr., Charlotte FAUCHER, Dr., Dominique DRAMAIS, Dr., Guillaume Carbonnelle, Dr., Jean-Pierre DELORD, Pr., Jocelyne PROVENCAL, Dr., Julien GAUTIER, Julien PERON, Dr., Laetitia STEFANI, Dr., Magali BRIERE, Dr., Marianne HAMON, Dr., Nicolas MARTIN, Dr, Roland SCHOTT, Dr., Simon PERNOT, Dr., Souad ASSAAD, Dr, Stéphane LEPRETRE, Dr., Xavier DURANDO, Pr., Yacine MERROUCHE, Dr. 2020-04-30
PEEP Incremental and Decremental Alveolar Recruitment of Critically Ill Corona Virus Disease-19 (COVID-19) Patients Coronavirus disease 19 infection Electric Impedance Tomography (EIT) alone, positive end-expiratory pressure (PEEP) decremental alveolar recruitment alone, positive end-expiratory pressure (PEEP) incremental alveolar recruitment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Szeged Budapesti Müszaki És Gazdaságtudományi Egyetem, Hochschule Furtwangen, Germany Hungary 2020-05-01 2021-04-19 COVID-19EIT, NCT04360837 Phase Not Applicable Not yet recruiting 1 11 Months 10 András Lovas, MD PhD 2020-05-01
ROCOCO: Serology COVID-19 From the Cornwall Hospital Union Coronavirus disease 19 infection immunoglobulin (IgG) Dia-Pro serological test alone, serum test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier de Cornouaille Centre Hospitalier Regional Universitaire de Brest France 2020-05-04 2020-11-04 29BRC20.0122, NCT04363593, ROCOCO Phase Not Applicable Not yet recruiting 1 6 Months 3200 Marie-Sarah FANGOUS, PH 2020-04-29
RESPIRE: Ruxolitinib for the Treatment of Acute Respiratory Distress Syndrome in Patients With COVID-19 Infection Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia ruxolitinib alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) L'Azienda USL Nord Ovest Azienda Ospedaliera Universitaria Senese, Azienda Ospedaliero, Universitaria Pisana, Fondazione Toscana Gabriele Monasterio Italy 2020-04-25 2020-05-31 2020.COVID-19.RUXO106, NCT04361903, RESPIRE Phase Not Applicable Not yet recruiting 1 1 Month 13 Barbara Dr Meini, Pharmacist, Enrico Dr Capochiani, hematologist 2020-04-29
SJTRC: St. Jude Tracking of Viral and Host Factors Associated With COVID-19 Coronavirus disease 19 infection blood sampling alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) St Jude Children's Research Hospital US 2020-04-23 2025-03-20 NCT04362995, SJTRC, SJTRC Phase Not Applicable Recruiting 0 58 Months 1517 Aditya H. Gaur, MD, Jeremie H. Estepp, MD, Joshua Wolf, MBBS, PhD, FRACP, Paul G. Thomas, PhD 2020-04-29
COPEP: Efficacy of Pragmatic Same-day COVID-19 Ring Prophylaxis for Adult Individuals Exposed to SARS-CoV-2 in Switzerland Coronavirus disease 19 infection Plaquenil alone, lopinavir + ritonavir alone HIV protease inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopitaux Universitaires De Geneve Switzerland 2020-04-30 2020-10-31 CCER 2020-00864, COPEP, NCT04364022 Phase 3 Clinical Recruiting 2 6 Months 420 Alexandra Calmy, Prof, Niklaus Labhardt, Prof 2020-04-29
OSACOVID-19: Obstructive Sleep Apnea and Covid-19 Outcomes Coronavirus disease 19 infection, Obstructive sleep apnea, Viral pneumonia polysomnography alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Koc University Turkey 2020-04-27 2020-12-31 2020.140.IRB1.030, NCT04363333, OSACOVID-19 Phase Not Applicable Recruiting 1 8 Months 275 The OSACOVID-19 Study Group, Yeliz Celik, MSc, Yuksel Peker, MD, PhD 2020-04-30
Arkansas Expanded Access COVID-19 Convalescent Plasma Treatment Program Coronavirus disease 19 infection convalescent plasma alone, acetaminophen plus diphenhydramine Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Arkansas 260944, NCT04363034 Phase Not Applicable Recruiting 0 Danielle Evans, David Avery 2020-04-30
PLACID: Study to assess the efficacy and safety of convalescent plasma in moderate COVID-19 disease Coronavirus disease 19 infection Usual care alone, convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Indian Council of Medical Research India 2020-04-22 CTRI/2020/04/024775, PLACID, Protocol v 1.1 Phase 2 Clinical Not yet recruiting 2 452 DR Sunita Bundas, Dr Anup Agarwal, Dr Aparna Mukherjee, Dr J R Khambolja 2020-05-04
A Pilot Study to Assess Hydroxychloroquine in Patients With SARS-CoV-2 (COVID-19) Coronavirus disease 19 infection, Viral pneumonia hydroxychloroquine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Oregon Health Sciences University OHSU Knight Cancer Institute US 2020-05-31 2021-06-30 NCT04363866, STUDY00021303 Phase 4 Clinical Not yet recruiting 0 13 Months 40 Brett Rodgers, Marcel Curlin, MD 2020-04-29
Novel Artificial Intelligence Algorithm to screen COVID-19 Patients from X-Ray , CT-Scan of Thorax and Voice Sampling through Android App and storage through Cloud Coronavirus disease 19 infection Android App alone, Chest X-Ray Artificial Intelligence Module alone, THORAX CT-Scan Artificial Intelligence Module alone, Voice Sampling Artificial Intelligence Module alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rabindranath Tagore Medical College India 2020-04-23 CTRI/2020/04/024776 Phase Not Applicable Recruiting 2 1650 Dr Arvind Kumar Morya, Dr Mahesh Mahich 2020-05-04
Immune Cells in Inflammatory Arthritis With Coronaviruses, Including COVID-19 Coronavirus disease 19 infection, Rheumatoid arthritis Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Manchester UK 2020-05-01 2021-05-01 282566, NCT04363047 Phase Not Applicable Not yet recruiting 1 12 Months 125 Anne C Barton, Dr. Sebastien Viatte, Lynne Macrae 2020-04-29
AdoPro-Cov19: Adolescents and Health Professionals Faced With the Necessity for Changing to Remote Care During the COVID-19 Outbreak Quarantine Coronavirus disease 19 infection Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Hôpital Cochin INSERM France 2020-05-31 2020-12-31 AdoPro-Cov19, NCT04363671, P20-670 Phase Not Applicable Not yet recruiting 1 7 Months 30 Carretier Emilie, Emilie Carretier, MD, Jonathan Lachal, PhD 2020-04-28
Clinical and Immunologic Impact of Perinatal SARS-CoV-2 (COVID-19) Infection Coronavirus disease 19 infection, Cough, Fever, Viral pneumonia Female Fundacion Infant Argentina 2020-05-01 2020-09-30 NCT04362956, PERINATAL COVID-19 Phase Not Applicable Not yet recruiting 1 5 Months 200 Gaston Ofman, Head of Perinatal Research, Gaston Ofman, MD 2020-04-29
RuXoCoil: Ruxolitinib for Treatment of Covid-19 Induced Lung Injury ARDS Coronavirus disease 19 infection, Viral pneumonia ruxolitinib (oral, myeloproliferative disorders), Incyte/Novartis alone Jak1 tyrosine kinase inhibitor, Jak2 tyrosine kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Philipps-Universitat Marburg Germany 2020-05-31 2020-11-30 KKS-278, NCT04359290, RuXoCoil Phase 2 Clinical Not yet recruiting 1 6 Months 15 Andreas Burchert, Prof Dr., Andreas Neubauer, Prof Dr. 2020-04-30
A medical records based study for epidemiological characteristics of 88 patients with new coronavirus pneumonia (COVID-19) and its impact on severe disease Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) First People's Hospital of Jiangxia District, Wuhan (Union Jiangnan Hospital) China 2020-01-29 2020-03-16 ChiCTR2000032239 Phase Not Applicable Recruiting 1 1 Month 88 Gu Xue 2020-04-29
COVIDITY: A Phase I Study of Vaccine SCIB-1 For the Treatment of COVID-19 Coronavirus disease 19 infection SCIB-1 alone Immunoglobulin Fc receptor modulator Scancell Ltd Nottingham Trent University, University of Nottingham UK 2021-03-31 COVIDITY Phase 1 Clinical Planned 1 Christopher Coleman, Dr. Sally Adams, Graham Pockley, James Dixon, Janet Daly, Jonathan Ball, Lindy Durrant 2020-04-29
CoCo-Neuro: Cohort of Patients With Covid-19 Presenting Neurological or Psychiatric Disorders Coronavirus disease 19 infection, Neurological disease, Psychiatric disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris 2020-04-24 2022-04-24 APHP200525, CoCo-Neuro, NCT04362930 Phase Not Applicable Not yet recruiting 0 24 Months 2000 CECILE DELORME, MD, Jean-Christophe CORVOL, MD,PHD 2020-04-29
Investigation of the B- and T-cell Repertoire and Immune Response in Patients With Acute and Resolved COVID-19 Infection Coronavirus disease 19 infection blood sampling alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Cancer Institute National Institutes of Health Clinical Center US 2020-04-27 2024-12-01 20-C-0103, 200103, NCT04362865 Phase Not Applicable Recruiting 0 55 Months 150 Leah E Hoffman, R.N., Robert J Kreitman, M.D. 2020-05-04
A trial to evaluate plasma therapy for the treatment of COVID-19 patients Coronavirus disease 19 infection plasma therapy alone Korea Center for Disease Control & Prevention South Korea Phase 2 Clinical Recruiting 1 2 2020-04-28
A clinical trial of a plasma therapy for the treatment of patients with Covid-19 Coronavirus disease 19 infection plasma therapy alone Korea Center for Disease Control & Prevention South Korea 2020-07-31 Phase Not Applicable Planned 1 2020-04-28
Hydroxychloroquine and Nitazoxanide Combination Therapy for COVID-19 Coronavirus disease 19 infection Hydroxychloroquine plus nitazoxanide Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Tanta University Egypt 2020-05-31 2020-12-31 HCQ/NTZ, NCT04361318 Phase 2/Phase 3 Clinical Not yet recruiting 1 7 Months 100 Kamal Okasha, MD, PhD 2020-04-30
Comparison of suspected or negative cases with confirmed cases of COVID-19 at Max Hospital Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Max Healthcare Institute Ltd, India India 2020-04-28 CTRI/2020/04/024772 Phase Not Applicable Not yet recruiting 1 90 Samreen Siddiqui, Sujeet Jha 2020-04-29