Last updated: May 15, 2020 - 02:00 BST
| Oral 25-hydroxyvitamin D3 and COVID-19 |
Coronavirus disease 19 infection |
25-hydroxyvitamin D3 alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Tehran University of Medical Sciences |
Boston University |
Iran |
2020-04-14 |
2021-03-15 |
IR.TUMS.VCR.REC.1399.061, IRCT2020-0401046909N2, IRCT20200401046909N1, NCT04386850 |
Phase 3 Clinical |
Recruiting |
0 |
11 Months |
1500 |
Arash shirvani, Mohamadali Sahraian, MD, Zhila Maghbooli, PhD, zhila Maghbooli, PhD, zhila maghbooli, PhD |
2020-05-14 |
| Study of the Safety of Therapeutic Treatment With an Immunomodulary Agent (N-803 in Adults With COVID-19) |
Coronavirus disease 19 infection |
N-803 alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
ImmunityBio Inc |
|
|
2020-05-11 |
2020-07-11 |
NCT04385849, QUILT-COVID-19 |
Phase 1b Clinical |
Not yet recruiting |
0 |
2 Months |
30 |
Jeff Safrit |
2020-05-14 |
| Vitamin D and COVID-19 Management |
Coronavirus disease 19 infection, Vitamin D deficiency |
ergocalciferol alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Alberta |
|
Canada |
2020-05-31 |
2020-12-31 |
00100606, NCT04385940 |
Phase 3 Clinical |
Not yet recruiting |
0 |
7 Months |
64 |
Aldo Montano-Loza |
2020-05-14 |
| Taiwan 'Aerosol Box' Versus UMMC 'Intubation Box' |
Coronavirus disease 19 infection |
Aerosol Box alone, Intubation Box alone |
|
Healthy volunteers accepted |
University of Malaya |
|
Malaysia |
2020-05-15 |
2020-12-30 |
2020410-8498, NCT04385576 |
Phase Not Applicable |
Recruiting |
0 |
7 Months |
30 |
Dr SHAIRIL RAHAYU BINTI RUSLAN, INA I SHARIFFUDDIN, MAnaes, MOHD F ZAINAL ABIDIN, MAnaes, SHAIRIL R RUSLAN, MAnaes(UM) |
2020-05-14 |
| Neonatal Complications of Coronavirus Disease (COVID-19) |
Coronavirus disease 19 infection |
|
|
Newborn Infants (up to 5 months) |
University of Oxford |
Imperial College London, Public Health England, St Georges University of London, University Hospital of Wales, University of Glasgow, University of Leicester, University of Nottingham |
UK |
2020-04-01 |
2021-09-30 |
14905, NCT04386109 |
Phase Not Applicable |
Recruiting |
0 |
18 Months |
500 |
Dr C Gale, MBBS,MSc,PhD, Professor J Kurinczuk, MBChB,MSc,MD |
2020-05-14 |
| SALICOV: Detection of COVID-19 in Saliva Collection |
Coronavirus disease 19 infection |
saliva sampling alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire D Amiens |
|
France |
2020-05-11 |
2020-08-31 |
NCT04386551, PI2020_843_0045, SALICOV |
Phase Not Applicable |
Recruiting |
0 |
3 Months |
225 |
Catherine François, MD, Etienne Brochot, MD, Jean-Luc Schmit, Pr, Jean-Philippe Lanoix, MD, Sandrine Castelain, Pr, Yves Edouard Herpe, Ing |
2020-05-14 |
| A Phase III, Double-blind, Randomized, Placebo-controlled, Multicenter Clinical Trial to Assess the Efficacy and Safety of VPM-1002 in Reducing Healthcare Professionals' Absenteeism in the SARS-CoV-2 Pandemic by Modulating the Immune System |
Coronavirus disease 19 infection, Respiratory disease |
VPM-1002 alone |
Listeriolysin stimulator |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Vakzine Projekt Management GmbH |
FGK Clinical Research GmbH |
Germany |
2020-05-18 |
2021-06-30 |
NCT04387409, VPM1002-DE-3.06COV |
Phase 3 Clinical |
Not yet recruiting |
1 |
13 Months |
1200 |
Leander Grode, Dr rer nat |
2020-05-14 |
| Ayurvedic Interventions in prevention of COVID-19 infection-A survey study |
Coronavirus disease 19 infection |
Ashwagandha plus Sanshamani Vati |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Central Council for Research in Ayurvedic Sciences |
|
India |
2020-05-16 |
|
CTRI/2020/05/025069 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
1324 |
Dr BCS Rao, Dr Babita Yadav |
2020-05-14 |
| A Study to Evaluate the Safety and Efficacy of MSTT1041A (Astegolimab) or UTTR-1147A in Patients With Severe COVID-19 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
RG-6149 alone, RG-7880 alone |
IL-22 agonist, Interleukin 1 like receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Genentech Inc |
|
US |
2020-05-20 |
2020-10-27 |
GA42469, NCT04386616 |
Phase 2 Clinical |
Not yet recruiting |
0 |
5 Months |
300 |
Clinical Trials |
2020-05-14 |
| CYCOV-II: Cytokine Adsorption in Patients With Severe COVID-19 Pneumonia Requiring Extracorporeal Membrane Oxygenation |
Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia |
Cytosorb adsorber alone, cytokine adsorption alone, extracorporeal membrane oxygenation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Klinikum der Albert-Ludwigs Universitaet Freiburg |
Kliniken Ludwigsburg-Bietigheim gGmbH, Klinikum Ibbenbüren, Ludwig-Maximilians University of Munich, Martin-Luther-Universitaet, SLK Klinikum Heilbronn GmbH, Saarland University Hospital, Universitat Ulm |
Germany |
2020-06-01 |
2021-10-31 |
CYCOV-II, CYCOV-II, NCT04385771 |
Phase Not Applicable |
Not yet recruiting |
1 |
17 Months |
80 |
Alexander Supady, Dr., MPH |
2020-05-14 |
| A clinical trial to investigate the anti-inflammatory properties of cannabidiol in COVID-19 patients with cardiac injury |
Coronavirus disease 19 infection, Heart injury |
cannabidiol alone |
|
|
Cardiol Therapeutics |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
|
|
2020-05-14 |
| A clinical trial of Ad5-nCoV for the treatment of COVID-19 infection |
Coronavirus disease 19 infection |
Ad5-nCoV alone |
COVID19 Spike glycoprotein modulator |
|
CanSino Biologics Inc, Canadian Center for Vaccinology, Canadian Immunization Research Network, National Research Council of Canada |
|
Canada |
|
|
|
Phase Not Applicable |
Planned |
1 |
|
|
|
2020-05-14 |
| CONNECTDEM: Cognitive Outcomes During COVID-19 confinement in Elderly and Their Caregivers Using Technologies for Dementia |
Acute stress disorder, Coronavirus disease 19 infection, Dementia, Depression, Mild cognitive impairment |
telephone interview alone |
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fundacion Publica Andaluza para la Investigacion de Malaga en Biomedicina y Salud |
Consorci Sanitari de Terrassa |
Spain |
2020-05-04 |
2020-06-30 |
CONNECT DEM, CONNECTDEM, NCT04385797 |
Phase Not Applicable |
Not yet recruiting |
2 |
1 Month |
414 |
Fermín Mayoral-Cleries, Fermín Mayoral-Cleries, MD, PhD, Jessica M Goodman-Casanova, RNCS, Maite Garolera, PhD, María Quintana, PhD |
2020-05-14 |
| Compassionate Use of Hyperbaric Oxygen Therapy |
Coronavirus disease 19 infection |
hyperbaric oxygen therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
SerenaGroup |
The Wound Treatment Center |
US |
2020-05-11 |
2022-05-11 |
HBOT-COVID-19, NCT04386265 |
Phase Not Applicable |
Recruiting |
0 |
24 Months |
100 |
Thomas E Serena, MD |
2020-05-14 |
| Kidney Injury Severity and COVID-19 |
Coronavirus disease 19 infection, Renal injury, Respiratory distress syndrome, Viral pneumonia |
CT scan alone, urine test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
IM Sechenov Moscow Medical Academy |
|
Russian Federation |
2020-05-15 |
2020-11-15 |
NCT04386564, SECHENOV-COVID19_AKI |
Phase Not Applicable |
Not yet recruiting |
1 |
6 Months |
120 |
Dmitry Enikeev, M.D., Ph.D., Dmitry Enikeev, MD, Mark Taratkin, M.D. |
2020-05-14 |
| A randomized, double-blinded, parallel-controlled clinical trial for azvudine in the treatment of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Standard of Care alone, azvudine alone |
Nucleoside reverse transcriptase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Beijing Ditan Hospital Capital Medical Universty |
|
China |
2020-05-12 |
|
ChiCTR2000032769 |
Phase 2 Clinical |
Recruiting |
6 |
|
342 |
Wan Yuanhao, Zhang Fujie |
2020-05-14 |
| Trial of Alpha-1 Antitrypsin Inhalation in Treating Patient With Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) |
Coronavirus disease 19 infection |
alpha-1 antitrypsin (iv, alpha-1 antitrypsin deficiency/type 1 diabetes/GvHD/ lung transplant rejection), Kamada/Shire alone |
Alpha 1 antitrypsin stimulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ministry of Health Saudi Arabia |
|
Saudi Arabia |
2020-06-01 |
2020-09-01 |
4-0520- 076-K-02-H, NCT04385836 |
Phase 0 Clinical |
Recruiting |
1 |
3 Months |
150 |
mohammed m othman, mtair |
2020-05-14 |
| Evaluation of the use of hydroxychlorochine in Chinese flu |
Coronavirus disease 19 infection |
proper COVID19 treatment alone, azithromycin plus hydroxychloroquine |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital da Criança Santo Antônio |
|
Brazil |
2020-05-01 |
|
Número do CAAE: 30585020.2.0000.0008, Número do Parecer do CEP: 3.982.682, RBR-3k4wxb, U1111-1250-7492 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
45 |
Marcos Aurelio Barboza de Oliveira |
2020-05-14 |
| Study of effect of Yashtimadhu tablet for the prevention of COVID -19 on healthy individuals |
Coronavirus disease 19 infection |
Yashtimadhu alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Ministry of Ayush |
|
India |
2020-05-18 |
|
CTRI/2020/05/025093 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
1200 |
Dr G Babu, Dr Sujata Pundalikrao Dhoke, Dr Sujata pundlikrao Dhoke |
2020-05-14 |
| The effect of zinc on the treatment and clinical course of patients with SARS-cov2 (COVID-19) |
Coronavirus disease 19 infection |
hydroxychloroquine sulfate plus zinc |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Isfahan University of medical Sciences |
|
Iran |
2020-04-20 |
|
IR.MUI.MED.REC.1399.074, IRCT20180425039414N2 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
|
80 |
Atousa Hakamifard, Ziba Farajzadegan |
2020-05-14 |
| Pa-COVID-19: Analysis of the Pathophysiology and Pathology of Corona Virus Disease 2019 |
Coronavirus disease 19 infection |
|
|
|
Charité Campus Virchow-Klinikum |
Charite Universitaetsmedizin Berlin |
Germany |
2020-03-01 |
|
DRKS00021688, EA2/066/20, Pa-COVID-19 |
Phase Not Applicable |
Recruiting |
1 |
|
1500 |
Florian Kurth, Leif-Erik Sander |
2020-05-14 |
| HOP-COVID: COVID-19 Infection in Healthcare Workers |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assistance Publique Hopitaux de Paris |
|
France |
2020-05-31 |
2020-10-31 |
APHP200483, HOP-COVID, NCT04386759 |
Phase Not Applicable |
Not yet recruiting |
1 |
5 Months |
6000 |
Sylvie BASTUJI-GARIN, MD, PhD |
2020-05-14 |
| A population-based study was to evaluate the whether androgen-deprivation therapies (ADTs) could protect patients affected by prostate cancer from SARS-CoV-2 infections |
Coronavirus disease 19 infection, Prostate tumor |
androgen-deprivation therapies alone |
|
|
Universita Degli Studi Di Padova |
|
Italy |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
|
Andrea Alimonti |
2020-05-14 |
| The Impact of COVID-19 on the Health Care Utilization of Inflammatory Bowel Disease |
Coronavirus disease 19 infection, Inflammatory bowel disease |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Keimyung University Dongsan Medical Center |
Yeungnam University College of Medicine |
South Korea |
2020-04-24 |
2021-03-30 |
2020-04-070, NCT04387279 |
Phase Not Applicable |
Recruiting |
3 |
11 Months |
800 |
Kyeong Ok Kim, Ph.D., Yoo Jin Lee, Yoojin Lee, M.D. |
2020-05-14 |
| Placebo-controlled clinical trial to evaluate the efficacy and safety of hydroxychloroquine and azithromycin in relation to placebo in the negative viral load of participants with SARS-CoV2 flu syndrome and who do not have an indication for hospitalization |
Coronavirus disease 19 infection, Viral pneumonia |
azithromycin plus hydroxychloroquine |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Hospital Santa Paula |
|
Brazil |
2020-04-11 |
|
3,964,568, 30413020.8.0000.0008, A 33166752803, RBR-95yjmq |
Phase 3 Clinical |
Recruiting |
1 |
|
108 |
Ana Tarina Alvarez Lopes |
2020-05-14 |
| Phase Ib/II Trial of Dendritic Cell Vaccine to Prevent COVID-19 in Frontline Healthcare Workers and First Responders |
Coronavirus disease 19 infection |
AV-COVID-19 alone, AV-COVID-19 plus GM-CSF |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Aivita Biomedical Inc |
|
|
2020-09-30 |
2021-04-30 |
CL-COV-P01-US, NCT04386252 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
0 |
7 Months |
180 |
Candace Hsieh, PhD, Robert O Dillman, MD |
2020-05-14 |
| Evaluating the Efficacy of Artesunate in Adults With Mild Symptoms of COVID-19 |
Coronavirus disease 19 infection |
artemisinin alone, artesunate alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Princess Nourah Bint Abdulrahman University |
|
Saudi Arabia |
2020-06-30 |
2020-12-31 |
IN PROCESS, NCT04387240 |
Phase 2 Clinical |
Not yet recruiting |
1 |
6 Months |
22 |
Abdulaziz S Algarni, MD, Osama Kentab, MD, Osama Y Kentab, MD |
2020-05-14 |
| APRV-COVID19: Evaluation of Airway Pressure Release Ventilation in COVID-19 ARDS |
Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia |
Airway pressure release ventilation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Central Hospital, Nancy, France |
|
France |
2020-05-15 |
2020-06-30 |
2020PI076, APRV-COVID19, NCT04386369 |
Phase Not Applicable |
Not yet recruiting |
1 |
1 Month |
40 |
Matthieu Koszutski, MD |
2020-05-14 |
| Study on the Use of Sarilumab in Patients With COVID-19 Infection |
Coronavirus disease 19 infection |
Variable regimens including chloroquine , hydroxychloroquine , sarilumab |
IL-6 receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
ASST Fatebenefratelli Sacco |
|
Italy |
2020-05-31 |
2020-12-31 |
COVID-SARI-001, NCT04386239 |
Phase 0 Clinical |
Not yet recruiting |
1 |
7 Months |
40 |
Agostino Riva, MD, Massimo Galli, Professor, Stefano Rusconi |
2020-05-14 |
| COVIDIMM: Immune Changes in Severe COVID-19 Pulmonary Infections |
Coronavirus disease 19 infection, Hypoxia, Lung infection, Respiratory failure |
NAVIOS flow cytometer (Beckman Coulter) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Central Hospital, Nancy, France |
|
France |
2020-03-30 |
2020-05-30 |
CHRU NANCY : 2020PI080_1, COVIDIMM, NCT04386395 |
Phase Not Applicable |
No longer recruiting |
1 |
2 Months |
15 |
MARIE REINE LOSSER, MD, PhD |
2020-05-14 |
| GYNE-COVID: Study of Late Fetal Loss in Poitou-Charentes |
Coronavirus disease 19 infection, Spontaneous abortion |
polymerase chain reaction alone |
|
Healthy volunteers accepted |
Centre Hospitalier Universitaire De Poitiers Etablissement D’Hospitalisation |
|
France |
2020-05-04 |
2021-07-04 |
GYNE-COVID, GYNE-COVID, NCT04387253 |
Phase Not Applicable |
Not yet recruiting |
1 |
14 Months |
80 |
|
2020-05-14 |
| Hydroxychloroquine prophylaxis in Covid 19 infection |
Coronavirus disease 19 infection, SARS coronavirus infection |
hydroxychloroquine alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Indian Council of Medical Research |
|
India |
2020-05-04 |
|
CTRI/2020/05/025010, HCQ Pro Study Protocol Version 1.3, |
Phase Not Applicable |
Status not specified |
6 |
|
2000 |
Dr Atul gogia, Dr Dorairajan Sureshkumar, Dr Neeraj Agarwal, Dr Suneela Garg, Dr Vikas Bhatia, Madhavi Eerike, Pranab Chatterjee, Prof Pankaja Raghav, Suman Kanungo |
2020-05-14 |
| A phase III clinical trial to compare Favipiravir with standard supportive care or standalone standard supportive care in subjects with mild to moderate COVID-19 |
Coronavirus disease 19 infection |
favipiravir alone, standard supportive care alone |
RNA polymerase inhibitor |
|
Glenmark Pharmaceuticals Ltd |
|
India |
|
|
|
Phase 3 Clinical |
Not yet recruiting |
1 |
|
150 |
|
2020-05-14 |
| An observational, retrospective study to evaluate hydroxychloroquine administration in patients with Covid-19 who had been admitted to the hospital |
Coronavirus disease 19 infection |
hydroxychloroquine alone |
|
|
New York State Department Of Health |
|
US |
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
1446 |
|
2020-05-14 |
| Evaluation of the effectiveness of rabbit antibody against coronavirus in patients |
Coronavirus disease 19 infection |
COVID-19 treatment alone, CoviGlobulin alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kowsar Biotechnology Co |
|
Iran |
2020-05-21 |
|
IR.BMSU.REC.1399.110, IRCT20200508047346N1 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
124 |
Dr. Mostafa Ghanei, Mahdi Behdani, Mostafa Ghanei, Sirous Zeinali |
2020-05-14 |
| CATALYST: A randomized, phase II proof of principle multi-arm multi-stage trial designed to guide the selection of interventions for phase III trials in hospitalized patients with COVID-19 infection |
Coronavirus disease 19 infection |
Drug therapy alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The University of Birmingham |
|
UK |
2020-05-05 |
|
2020-001684-89, CATALYST, RG_20-030 |
Phase 2 Clinical |
Recruiting |
1 |
|
|
|
2020-05-14 |
| Outcomes of viral infection in hematology patients |
Coronavirus disease 19 infection, Hematological disease |
|
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Science and Engineering Research Board |
|
India |
2020-05-28 |
|
CTRI/2020/05/025092 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
250 |
Biju George |
2020-05-14 |
| Knowledge status of public about COVID 19 disease prevention and control in Tamil Nadu |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Siddha Central Research Institute |
|
India |
2020-05-20 |
|
CTRI/2020/05/025091 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
125 |
Dr C Anbarasi, Dr R Meena, Dr S Natarajan |
2020-05-14 |
| COVID MILK: COVID MILK |
Coronavirus disease 19 infection |
|
|
|
Emma Childrens Hospital Foundation |
|
Netherlands |
2020-05-01 |
2020-06-30 |
COVID MILK, Trial NL8575 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
60 |
Johannes (Hans) B. van Goudoever |
2020-05-14 |
| COVUSd: COVID19 ultrasound diagnosis |
Coronavirus disease 19 infection |
ultrasound alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Isala |
|
Netherlands |
2020-04-18 |
2020-06-01 |
COVUSd, Trial NL8544 |
Phase Not Applicable |
Recruiting |
1 |
1 Month |
50 |
Svenja Haak |
2020-05-14 |
| CVC for COVID-19: Charite Trial of Cenicriviroc (CVC) Treatment for COVID-19 patients |
Coronavirus disease 19 infection |
cenicriviroc alone, standard of care alone |
CCR2 chemokine antagonist, CCR5 chemokine antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Charite Universitaetsmedizin Berlin |
|
Germany |
2020-05-11 |
|
2020-001493-29, CVC for COVID-19, CVC-for-COVID-19 |
Phase 2 Clinical |
Recruiting |
1 |
|
200 |
Dept. of Hepatology and Gastroenter |
2020-05-13 |
| A randomized-controlled study to investigate the potential efficacy of monalizumab compared to standard of care against COVID-19 in cancer patients with mild symptoms |
Coronavirus disease 19 infection |
monalizumab alone |
NKG2 A B activating NK receptor antagonist |
|
Centre Leon Berard, Innate Pharma SA |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-05-13 |
| A randomized-controlled study to investigate the potential efficacy of avdoralimab compared to standard of care against COVID-19 in cancer patients with pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
avdoralimab (IPH5401) alone |
CXCR1 chemokine antagonist, Complement C5a receptor antagonist, IL-8 receptor antagonist, Monocyte chemotactic protein 1 ligand inhibitor |
|
Centre Leon Berard, Innate Pharma SA |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-05-13 |
| Radiotherapy in COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
pulmonary radiotherapy 0.5 Gy alone, standard treatment alone |
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shaheed Beheshti Medical University |
|
Iran |
2020-05-21 |
2020-07-22 |
IR.SBMU.RETECH.REC.1399.073, IRCT20200509047366N1 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
2 Months |
5 |
Ahmad Ameri, Nazanin Rahnama, Rahnama, Rezaei Tavirani |
2020-05-13 |
| MPN-COVID: Myeloproliferative Neoplasms (MPN) and COVID-19 |
Coronavirus disease 19 infection, Myelofibrosis, Polycythemia, Polycythemia vera |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fondazione per la Ricerca Ospedale Maggiore |
European Leukemia Net |
UK, Germany, Spain, Denmark, Italy, France |
2020-05-01 |
2020-09-01 |
FROM - O-MPN-COVID-2020, MPN-COVID, NCT04385160 |
Phase Not Applicable |
Not yet recruiting |
39 |
4 Months |
80 |
Alessandra Carobbio, BioStat, Alessandra Iurlo, Alessandro Maria Vannucchi, Andrea Patriarca, Arianna Masciulli, PharmD, Chiara Paoli, Claire Harrison, Clara De Ambrogi, Daniele Vanni, Denise Soldati, Elena Elli, Elena Rossi, Elisa Rumi, Emilia Florea, Fabrizio Cavalca, Francesca Pirillo, Giulia Benevolo, Giulia Desa, Giuseppe Rossi, Hans Carl Hasselbalch, Ida Martinelli, Ilaria Nichele, Jean-Jacques Kiladjian, Luigi Scaffidi, Marco Ruggeri, Massimiliano Bonifacio, Monia Marchetti, Paola Guglielmelli, Rosa Daffini, Rosalba Sciancalepore, Silvia Artuso, Silvia Betti, Stefania Priolo, Steffen Koschmieder, Valerio De Stefano |
2020-05-14 |
| Evaluating the effect of intravenous hydrocortisone, methylprednisolone, and dexamethasone in treatment of patients with moderate to severe acute respiratory distress syndrome caused by COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
dexamethasone alone, hydrocortisone alone, methylprednisolone alone, routine care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Hamadan University of Medical Sciences |
|
Iran |
2020-06-04 |
|
IR.UMSHA.REC.1399.152, IRCT20120215009014N354 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
81 |
Dr Abbas Taher, Dr. Fariba Keramat, Dr. Jalal Poorolajal, Dr. Saeid Bashirian |
2020-05-14 |
| COSiN: Collection of Coronavirus COVID-19 Outbreak Samples in New South Wales |
Coronavirus disease 19 infection |
blood sampling alone |
|
|
National Centre in HIV Epidemiology and Clinical Research |
|
Australia |
2020-05-06 |
2021-06-30 |
COSiN, NCT04383652, VISP2005 |
Phase Not Applicable |
Recruiting |
9 |
13 Months |
200 |
Adam Bartlett, Angie Pinto, Bernard Hudson, Gail Matthews, Jeffrey Post, Marianne Martiello, Marianne Martinello, Michael Mina, Nicky Gilroy, Rowena Bull, William Rawlinson |
2020-05-13 |
| A global study to evaluate the safety, tolerability and efficacy of the immunoglobulin therapy (COVID-19), CoVIg-19 Plasma Alliance in adult patients with COVID-19 |
Coronavirus disease 19 infection |
anti-SARS-CoV-2 polyclonal hyperimmune immunoglobulin therapy (COVID-19), CoVIg-19 Plasma Alliance/ Takeda/ CSL Behring alone |
|
|
CoVIg-19 Plasma Alliance, National Institute of Allergy and Infectious Diseases |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-05-13 |
| COVIDAge Study: Outcomes in Hospitalized Older Patients With COVID-19 |
Coronavirus disease 19 infection |
|
|
Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hopitaux Universitaires De Geneve |
|
Switzerland |
2020-03-13 |
2020-04-14 |
2020-00819, COVIDAge Study, NCT04385212 |
Phase Not Applicable |
Completed |
1 |
1 Month |
230 |
Christine Serratrice |
2020-05-13 |
| A phase I clinical study of COVID-19 vaccine (measles vaccine vector technology), Institut Pasteur/Themis Bioscience/University of Pittsburgh for the potential prevention of COVID-19 infection |
Coronavirus disease 19 infection |
COVID-19 vaccine (measles vaccine vector technology), Institut Pasteur/Themis Bioscience/University of Pittsburgh alone |
|
|
Themis Bioscience GmbH |
ABL Europe |
|
|
|
|
Phase 1 Clinical |
Planned |
0 |
|
|
|
2020-05-13 |
| MASC- study: Metabolic syndrome And Severity of Covid-19 |
Coronavirus disease 19 infection, Metabolic syndrome X |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sint Franciscus Gasthuis |
|
Netherlands |
2020-04-28 |
2020-06-01 |
2020-041, MASC- study, NL8580 |
Phase Not Applicable |
Recruiting |
1 |
1 Month |
100 |
Cathelijne van Zelst |
2020-05-13 |
| TBA: Lung ultrasound findings in patients with novel SARS CoV2 |
Coronavirus disease 19 infection |
lung ultrasound alone |
|
|
Amsterdam UMC |
|
Netherlands |
2020-03-26 |
2020-04-23 |
FWA00017598, NL8540, TBA |
Phase Not Applicable |
No longer recruiting |
1 |
|
50 |
Mark Haaksma |
2020-05-14 |
| COVID KIDS: Humoral responses to SARS-CoV-2 infection in children |
Coronavirus disease 19 infection |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Stichting Steun Emma Kinderziekenhuis AMC |
|
Netherlands |
2020-04-12 |
2021-04-04 |
COVID KIDS, NL73556.018.20, NL8531 |
Phase Not Applicable |
Recruiting |
1 |
11 Months |
420 |
Dasja Pajkrt |
2020-05-14 |
| Malaysian COVID-19 Anosmia Study (Phase II) - A Nationwide, Multicenter, Case-Control Study |
Coronavirus disease 19 infection, Dysgeusia, Dysomia |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sultanah Bahiyah Hospital |
HOSPITAL RAJA PEREMPUAN ZAINAB II, Hospital Enche' Besar Hajjah Khalsom, Hospital Kuala Lumpur, Hospital Permai, Hospital Queen Elizabeth, Hospital Raja Permaisuri Bainun, Hospital Sultan Ismail, Hospital Sultanah Maliha, Hospital Sungai Buloh, Hospital Tuanku Fauziah, Melaka Hospital, Pulau Pinang Hospital, Sarawak General Hospital, Sultanah Aminah Hospital, Sultanah Nur Zahirah Hospital, Tuanku Jaafar Hospital |
Malaysia |
2020-05-31 |
2020-08-31 |
MCO-002, NCT04384042 |
Phase 2 Clinical |
Not yet recruiting |
18 |
3 Months |
60 |
Amran Mohamad, MD MS, Anilawati Mat Jelani, MD MMed, Chee Loon Leong, MBBS MMed, Chenthilnathan Periasamy, MBBS MMed, Chun Yiing Wong, MBBS MMed, Dzawani Muhamad, MD MMed, Elang Kumaran Krishnan, MBBS MS, Fadzilah Ismail, MD MS, Halimuddin Sawali, MBBS MS, Heng Gee Lee, MBChB MRCP, Ibtisam Ismail, BSc, Ida Sadja'ah Sachlin, MBBS MMed, Jeyasakthy Saniasiaya, MMed FEBORL, Jothi Shanmuganathan, MBBS MMed, Kuldip Kaur Prem Kaur, MBBS MPH, Lee Lee Low, MD MRCP, Linda Pei Fang Lim, MD MS, Mahiran Mustafa, MBBCh MMed, Masliza Zaid, MBBS MMed, Mohd Noor Ismail, MD MRCP, Mohd Zambri Ibrahim, MD MMed, Nor Zaila Zaidan, MD MMed, Norzi Gazali, MBBS MMed, Philip Rajan Devesahayam, MMed FRCS, Rosdi Ramli, MBBS MMed, Shahrul Aiman Soelar, B Ind Stats, Sharifah Baizura Syed Alwi, MD MRCPI, Shen-Han Lee, MB PhD MRCS, Siti Sabzah Hashim, MD MS, Siti Sabzah Mohd Hashim, MD MS, Sobani Din, MD MS, Suhaila Abd Wahab, MBBS MMed, Suhaimi Yusof, MBBS MMed, Suhaimi Yusuf, MBBS MMed, Tengku Mohamed Izam Tengku Kamalden, MS FRCS, Tiang Koi Ng, MBBS MRCP, Ting Soo Chow, MD MRCP, Zhi Xiang Yeoh, MBBS MS MRCS, Zulkiflee Salahuddin, MD MS |
2020-05-14 |
| ICOS: International SARS-CoV-2 (COVID-19) Infection Observational Study |
Coronavirus disease 19 infection, Dyspnea |
biological sampling alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Minnesota |
National Institute of Allergy and Infectious Diseases, National Institutes of Health |
US, Denmark, Argentina, UK |
2020-05-15 |
2021-06-30 |
75N91019D00024, ICOS, ICOS, NCT04385251 |
Phase Not Applicable |
Not yet recruiting |
3 |
13 Months |
10000 |
Edward Gardner, Eileen Denning, James Neaton, PhD, Jens Lundgren, Sarah Pett |
2020-05-14 |
| COVIDNA: Pre-exposure Prophylaxis With Hydroxychloroquine in Sanitaries Highly Exposed to COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
hydroxychloroquine alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Fundación Pública Miguel Servet |
Instituto de Salud Carlos III |
Spain |
2020-04-23 |
|
2020-001697-30, COVIDNA, COVIDNA |
Phase 3 Clinical |
No longer recruiting |
1 |
|
200 |
RUTH GARCÍA |
2020-05-14 |
| Lung ultrasound and computed tomography for monitoring SARS-CoV-2 in critical care departments |
Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia |
Lung ultrasound monitoring alone, computed tomography monitoring alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Amsterdam UMC |
|
|
2020-03-27 |
2020-05-10 |
NL8584 |
Phase Not Applicable |
Recruiting |
0 |
1 Month |
80 |
Micah Heldeweg |
2020-05-14 |
| Validation of 3D nasopharyngeal swab |
Coronavirus disease 19 infection |
3D nasopharyngeal swab validation alone |
|
|
Universiti Sains Islam Malaysia |
|
Malaysia |
2020-05-18 |
2020-11-19 |
54849, NMRR-20-879-54849 |
Phase Not Applicable |
Not yet recruiting |
1 |
6 Months |
30 |
Dr Nor Eyzawiah Binti Hassan, Dr SITI ASMAT BINTI MD AREPEN |
2020-05-14 |
| COH-FIT: Collaborative Outcomes Study on Health and Functioning During Infection Times |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Padova |
Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health Inc |
Greece |
2020-04-26 |
2022-06-30 |
COH-FIT, COH-FIT, NCT04383470 |
Phase Not Applicable |
Recruiting |
1 |
26 Months |
100000 |
Agorastos Agorastos, Agorastos Agorastos, MD, Andres Estradè, MSc, Christoph U. Correll, MD, Marco Solmi, MD |
2020-05-13 |
| RISC: Role of Ibuprofen and Other Medicines on Severity of Coronavirus Disease 2019 |
Coronavirus disease 19 infection |
|
|
|
University Hospital, Bordeaux |
Bordeaux PharmacoEpi |
France |
2020-05-11 |
2020-07-31 |
CHUBX 2020/13, NCT04383899, RISC |
Phase Not Applicable |
Not yet recruiting |
9 |
2 Months |
200 |
Alexandre BOYER, Pr, Anne-Marie LEROI, Pr, Denis MALVY, Pr, Didier GRUSON, Pr, Duc NGUYEN, Dr, Florentia KAGUELIDOU, Dr, Jean-Jacques KILADJIAN, Pr, Jean-Luc CRACOWSKI, Pr, Jean-Sébastien HULOT, Pr, Marc BARDOU, Pr, Nicholas MOORE, Pr, Patrick BLIN, Dr, Rachel FROGET, Dr |
2020-05-14 |
| Fear Among Dentists During COVID-19 Pandemic |
Anxiety disorder, Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cairo University |
|
Egypt |
2020-03-02 |
2020-05-05 |
COVID-19 PANDEMIC, NCT04383626 |
Phase Not Applicable |
Completed |
1 |
2 Months |
216 |
|
2020-05-13 |
| 'Investigation of the Relationship Between New Coronary Virus Disease (COVID-19) and Anxiety and Depressive Symptoms in Pregnant Women' |
Anxiety disorder, Coronavirus disease 19 infection, Depression |
|
|
Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Istanbul Bakirkoy Maternity and Children Diseases Hospital |
|
Turkey |
2020-04-25 |
2020-07-26 |
BECKCOVID, NCT04384887 |
Phase Not Applicable |
No longer recruiting |
1 |
3 Months |
100 |
Pınar Yalcin bahat |
2020-05-13 |
| Covid-19 Triage Using Camera-based AI |
Coronavirus disease 19 infection |
RIA-device (Remote Investigation and Assessment) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Vastra Gotaland Region |
Detectivio Ab |
Sweden |
2020-05-31 |
2020-12-31 |
NCT04383457, U1111-1251-4114 |
Phase Not Applicable |
Not yet recruiting |
1 |
7 Months |
500 |
Ronny K Gunnarsson, MD PhD, Stefan Malmberg, MD |
2020-05-13 |
| Efficacy and Tolerability of Hydroxychloroquine in Adult Patients With COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia, Viral respiratory tract infection |
Plaquenil alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Taoyuan General Hospital |
Center For Disease Control Department Of Health Taiwan Roc, Center for Drug Evaluation, Taiwan, National Health Research Institutes, Taiwan Food and Drug Administration |
Taiwan |
2020-04-01 |
2020-09-30 |
NCT04384380, TYGH109014 |
Phase 4 Clinical |
Recruiting |
1 |
6 Months |
45 |
Chien-Yu Cheng, Dr., Jang-bin Chen, Dr., Shu-Hsing Cheng, Dr., YUNG-NIEN HSU, Dean, Yi-Chun Lin, Dr. |
2020-05-14 |
| Surveillance of Individuals Following SARS-CoV-2 Exposure |
Coronavirus disease 19 infection |
antibody assays alone, reverse transcription-polymerase chain reaction (RT-PCR) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Institute of Allergy and Infectious Diseases |
National Institutes of Health Clinical Center |
US |
2020-05-18 |
2023-06-16 |
20-I-0117, 200117, NCT04383444 |
Phase Not Applicable |
Recruiting |
0 |
36 Months |
1050 |
Lisa A Barnhart, R.N., Steven M Holland, M.D. |
2020-05-14 |
| Outcome of COVID-19 Patients After Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome |
Coronavirus disease 19 infection, Respiratory distress syndrome |
extracorporeal membrane oxygenation therapy alone |
|
|
Karolinska University Hospital |
HELSINKI UNIVERSITY HOSPITAL |
France, Sweden, UK, Germany, Italy, Finland |
2020-03-01 |
2020-12-31 |
COVID-19 ECMO, NCT04383678 |
Phase Not Applicable |
Recruiting |
11 |
10 Months |
200 |
Andrea Perrotti, Antonio Fiore, Antonio Loforte, Enrico Leo, Fausto Biancari, Fausto Biancari, Professor, Giovanni Mariscalco, Henryk Welp, Lars M Broman, Magnus Dalen, Magnus Dalen, Assoc prof, Magnus Dalén, Nicla Settembre, Svante Zipfel, Vito G Ruggieri |
2020-05-14 |
| A randomized controlled trial of hydroxychloroquine prophylaxis for Healthcare Workers exposed to COVID-19 |
Coronavirus disease 19 infection |
hydroxychloroquine alone, standard care Personal protective equipment alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
George Institute for Global Health India |
|
India |
2020-06-15 |
|
CTRI/2020/05/025067 |
Phase 2 Clinical |
Not yet recruiting |
3 |
|
10990 |
Dr Bala Venkatesh, Dr Bharath Kumar, Professor Vivekanand Jha |
2020-05-14 |
| COVER-PRO: Evaluation of Emergency Department (ED) Staff Stress Level During COVID-19 Pandemic |
Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection |
stress and anxiety questionnaire alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospices Civils De Lyon |
|
France |
2020-04-18 |
2020-08-18 |
69HCL20_0330, COVER-PRO, NCT04383886 |
Phase Not Applicable |
Recruiting |
5 |
4 Months |
200 |
Guillaume DURAND, MD, Julien BERTHILLER, Karim TAZAROURTE, MD, Laurent JACQUIN, MD, Marion DOUPLAT, MD, Vanessa LABEYE, MD |
2020-05-14 |
| GERONIMO 19: Study of the Efficiency of Normal Human Immunoglobulins (Ivig) in Patients Aged 75 Years and over Covid-19 with Severe Acute Respiratory Failure |
Coronavirus disease 19 infection, Respiratory failure |
polyvalent intravenous immunoglobulin alone, tandard management alone |
|
Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Central Hospital, Versailles |
|
France |
2020-04-27 |
|
2020-001768-27, GERONIMO 19, P20/07 |
Phase 2 Clinical |
Recruiting |
1 |
|
|
Mélody FORT |
2020-05-13 |
| SINUS WASH: Sinus-Wash Pilot Study |
Coronavirus disease 19 infection |
betadine alone, vedine alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hampshire Hospitals NHS Foundation Trust |
|
UK |
2020-05-01 |
|
2020-001721-31, SINUS WASH, SPON-AK-0420 |
Phase 2 Clinical |
Recruiting |
1 |
|
40 |
Chief Investigator |
2020-05-13 |
| RECOVER: A Randomized, Open-label, Phase-II Clinical Trial with or without Infusion of Plasma from Subjects after Convalescence of SARS-CoV-2 Infection in High-Risk Patients with Confirmed Severe SARS-CoV-2 Disease |
Coronavirus disease 19 infection |
convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Heidelberg |
German Federal Ministry of Education and Research |
Germany |
2020-04-05 |
|
2020-001632-10, EudraCT-N° 2020-001632-10, RECOVER, SARS-CoV-2CP-HD-001 |
Phase 2 Clinical |
Recruiting |
1 |
|
174 |
Prof. Dr. Carsten Müller-Tidow |
2020-05-14 |
| COVID-19 Prophylaxis With Hydroxychloroquine Associated With Zinc For High-Risk Healthcare Workers |
Coronavirus disease 19 infection |
hydroxychloroquine plus zinc sulfate |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Nucleo De Pesquisa E Desenvolvimento De Medicamentos Da Universidade Federal Do Ceara |
Federal University of Ceara |
Brazil |
2020-05-31 |
2020-10-31 |
HCQZN, NCT04384458 |
Phase 2 Clinical |
Not yet recruiting |
1 |
5 Months |
400 |
A, Elisabete A Moraes (betemora), Elisabete A Moraes, Professor |
2020-05-14 |
| ALLIANCE: International ALLIANCE Study of Therapies to prevent progression of COVID-19, a randomized trial |
Coronavirus disease 19 infection |
Variable regimens including Vit B12 , Vit D3 , Vitamin C , azithromycin , hydroxychloroquine , zinc |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Rinehart Medical Foundation |
National Institute of Integrative Medicine |
US, Australia |
2020-05-18 |
2021-06-30 |
ACTRN12620000557932p, ALLIANCE |
Phase 2 Clinical |
Not yet recruiting |
2 |
13 Months |
200 |
A/Prof Karin Ried |
2020-05-14 |
| ADAPT: COVID-19 Study - A prospective, observational cohort study at St Vincent’s Hospital Sydney |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
St Vincents Hospital Sydney Ltd |
|
Australia |
2020-05-14 |
2022-05-31 |
ACTRN12620000554965, ADAPT |
Phase Not Applicable |
Not yet recruiting |
1 |
24 Months |
300 |
A/Prof Gail Matthews |
2020-05-13 |
| Organicell Flow for Patients With COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
Organicell flow alone, standard care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Organicell Regenerative Medicine |
|
US |
2020-05-31 |
2020-12-31 |
19881, NCT04384445 |
Phase 1 Clinical |
Not yet recruiting |
0 |
7 Months |
20 |
George C Shapiro, MD, Maria I Mitrani, MD, PhD, Maria I Mitrani, MD. PhD, William Kapp, MD |
2020-05-13 |
| Accelerated iTBS for Depressed Patients During the COVID-19 Pandemic |
Coronavirus disease 19 infection, Major depressive disorder, Psychotic disorder |
B70 Fluid-Cooled Coil alone, MagPro X100 stimulator alone, accelerated intermittent theta burst stimulation alone, relapse prevention treatment alone, virtual check-in alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre for Addiction and Mental Health |
|
Canada |
2020-05-01 |
2022-11-01 |
059/2020, NCT04384965 |
Phase Not Applicable |
Recruiting |
1 |
30 Months |
200 |
Daniel Blumberger, MD, Mawahib Semeralul, Nicole Schoer |
2020-05-13 |
| Health and Wellbeing of Pregnant and Post-Partum Women During the COVID-19 Pandemic |
Coronavirus disease 19 infection |
online survey alone |
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Pregistry |
Harvard TH Chan School of Public Health |
US |
2020-05-20 |
2020-08-31 |
0002, NCT04385238 |
Phase Not Applicable |
Not yet recruiting |
0 |
3 Months |
25000 |
Diego Wyszynski, MD, MHS, PhD, Karestan Koenen, PhD, Sonia Hernandez-Diaz, MD, DrPh |
2020-05-13 |
| TX-COVID19: TX-COVID19 |
Coronavirus disease 19 infection |
Nebulization alone, Homeostec plus Paracetamol |
|
|
Cancerology State Institute, Colima State Health Services, Universidad de Colima |
|
Mexico |
2020-05-20 |
2021-01-15 |
RPCEC00000309, TX-COVID19 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
7 Months |
50 |
Delgado Enciso, Paz Garcia |
2020-05-14 |
| COV2-CP: Hyperimmune Plasma in Patients With COVID-19 Severe Infection |
Coronavirus disease 19 infection |
plasma hyperimmune therapy alone, standard therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Universita' Degli Studi "Magna Graecia" Di Catanzaro |
Azienda Ospedaliera Bianchi Melacrino Morelli, Azienda Ospedaliera Universitaria Mater Domini di Catanzaro, Azienda Sanitaria Provinciale Di Catanzaro, Hospital of Cosenza |
Italy |
2020-05-01 |
2021-05-15 |
COV2-CP, COVID-19 CONVALESCENT PLASMA, NCT04385043 |
Phase 2/Phase 3 Clinical |
Recruiting |
6 |
12 Months |
400 |
Alfonso Trimarchi, MD, Andrea Dominijanni, MD, Carlo Torti, MD, Federico Longhini, MD, Francesco Zinno, MD, Gabriella Talarico, MD, Giovanni Matera, MD, Luca Gallelli, Lucio Cosco, MD, Maria Laura Guzzo, MD, Paola Grandini, MD, Pasquale Minchella, MD, Patrizia Leonardo, MD, Piero Gangemi, MD |
2020-05-14 |
| ISCA: Inhaled Sedation in COVID-19-related Acute Respiratory Distress Syndrome (ISCA): an International Research Data Study in the Recent Context of Widespread Disease Resulting From the 2019 (SARS-CoV2) Coronavirus Pandemics (COVID-19) |
Coronavirus disease 19 infection, Respiratory distress syndrome |
Inhaled sedation alone, Intravenous sedation alone, isoflurane alone, sevoflurane alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Clermont-Ferrand |
Groupe Hospitalier Pitie-Salpetriere, University of Valencia, Universitätsklinikum Schleswig-Holstein |
Germany, Spain, France |
2020-05-31 |
2020-12-31 |
ISCA, ISCA STUDY, NCT04383730 |
Phase Not Applicable |
Not yet recruiting |
6 |
7 Months |
400 |
Caroline Varillon, Jean-Michel Constantin, Lise Laclautre, Matthieu Jabaudon, Pierre Boucher, Rafael Badenes |
2020-05-14 |
| ACTT 2: A randomized, controlled clinical trial evaluating the safety and efficacy of a remdesivir plus baricitinib for coronavirus disease 2019 (COVID-19) |
Coronavirus disease 19 infection |
baricitinib plus remdesivir |
Coronavirus non structural protein 8 modulator, Jak1 tyrosine kinase inhibitor, Jak2 tyrosine kinase inhibitor, RNA polymerase modulator |
|
National Institutes of Health |
National Institute of Allergy and Infectious Diseases |
US |
2020-05-08 |
|
ACTT 2 |
Phase Not Applicable |
Recruiting |
0 |
|
|
|
2020-05-13 |
| StayHome: Early Hydroxychloroquine to Reduce Secondary Hospitalization and Household Transmission in COVID-19 |
Coronavirus disease 19 infection |
hydroxychloroquine alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Lausanne |
|
Switzerland |
2020-05-12 |
2020-10-31 |
NCT04385264, StayHome, UNISANTE |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
5 Months |
800 |
Alix Miauton, MD, Blaise Genton, MD-PhD, Jacques Cornuz, MD-PhD, Mary-Anne Hartley, MD, PhD MPH, Mary-Anne Hartley, MD, PhD, MPH, Valérie D'Acremont, MD-PhD |
2020-05-13 |
| Covid-19 Pandemic: Patients Experience in T1D |
Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression, Diabetic ketoacidosis, Hypoglycemia, Insulin dependent diabetes |
|
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
McGill University |
Canadian Institutes of Health Research, Juvenile Diabetes Research Foundation |
Canada |
2020-04-29 |
2021-01-01 |
2021-1079, NCT04384471 |
Phase Not Applicable |
Recruiting |
1 |
8 Months |
384 |
Anne-Sophie Brazeau, PhD |
2020-05-13 |
| Familles-COVID: Psychological Impact of the Hospitalization of a Family Member in Intensive Care for Covid-19 Infection |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hopitaux Universitaires de Strasbourg |
|
France |
2020-05-31 |
2021-02-28 |
7761, Familles-COVID, NCT04385121 |
Phase Not Applicable |
Not yet recruiting |
1 |
9 Months |
60 |
Ferhat MEZIANI, Julie HELMS |
2020-05-13 |
| Safety and Immunogenicity Study of Inactivated Vaccine for Prevention of SARS-CoV-2 Infection (COVID-19) |
Coronavirus disease 19 infection |
inactivated SARS-CoV-2 vaccine (vero cells) alone |
|
Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sinovac Research & Development Co Ltd |
|
China |
2020-05-20 |
2020-07-20 |
NCT04383574, PRO-NCOV-1002 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
2 Months |
422 |
Hui Jin, Yuliang Zhao, Master |
2020-05-13 |
| Rapid Detection 2019-nCOV via Surface Plasamon Resonance |
Coronavirus disease 19 infection |
RT-PCR method alone, Surface Plasamon Resonance method alone |
|
|
Southeast University, The Affiliated Zhongda Hospital of Southeast University |
National Natural Science Foundation of China |
China |
2020-05-25 |
2021-03-19 |
ChiCTR2000032842 |
Phase 0 Clinical |
Not yet recruiting |
1 |
9 Months |
400 |
Wenjing Xu, Yewei Zhang |
2020-05-13 |
| The Geneva Covid-19 CVD Study |
Acute coronary syndrome, Cardiac failure, Coronavirus disease 19 infection, Heart arrhythmia, Myocarditis |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hopitaux Universitaires De Geneve |
|
Switzerland |
2020-03-24 |
2022-03-31 |
CCER-2020-00610, NCT04384029 |
Phase Not Applicable |
No longer recruiting |
1 |
24 Months |
7000 |
Francois MACH |
2020-05-13 |
| Inactivated Convalescent Plasma as a Therapeutic Alternative in Patients CoViD-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome, Sepsis, Septic shock, Viral pneumonia |
inactivated convalescent plasma alone, support treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Blood Center Foundation, Hemolife |
Universidad de Antioquia |
Colombia |
2020-05-20 |
2020-11-30 |
CT01, NCT04385186 |
Phase 2 Clinical |
Not yet recruiting |
9 |
6 Months |
60 |
Amanda E Maestre, MD, PhD, Ana L Muñoz, MSc, PhD, Andrés F Zuluaga, MD, PhD, Carlos A Arbélaez, MD, MSc, Daniel C Aguilar, MSc, PhD, Diego Gómez, MD, MSc, Diego Gómez, MD, Msc, Diego Gómez, MD. MSc, Fabian H Muñoz, MD, MSc, Harold Alvaréz, MD, MSc, Miguel G Rueda, MD, MSc |
2020-05-14 |
| COVIDBioToul: Predictive Immune Biomarkers for COVID-19 Pathogenesis |
Coronavirus disease 19 infection, Respiratory distress syndrome |
blood collection alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire de Toulouse |
|
France |
2020-05-12 |
2021-12-31 |
COVIDBioToul, NCT04385108, RC31/20/0162 |
Phase Not Applicable |
Not yet recruiting |
1 |
19 Months |
170 |
Guillaume MARTIN-BLONDEL, MD PhD |
2020-05-14 |
| COV-HI: COVID-19 Hyperinflammation Syndrome (COV-HI): Protocol for a Rapidly Executed Cohort Study |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University College London |
Newcastle Upon Tyne Hospitals NHS Trust, Nottingham University Hospital, Sheffield Teaching Hospitals NHS Foundation Trust, The Leeds Teaching Hospitals NHS Trust, England, University College London Hospital |
UK |
2020-04-16 |
2020-07-05 |
132388, COV-HI, NCT04385069 |
Phase Not Applicable |
Recruiting |
5 |
2 Months |
500 |
Amanda Ledlie, Jessica Manson, Dr, Joe West, Prof., Matthew Collin, Prof., Rachel Tattershall, Sinisa Savic |
2020-05-14 |
| Genetic Basis of COVID-19 Infection |
Coronavirus disease 19 infection |
whole exome sequencing alone |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Mansoura University |
|
Egypt |
2020-05-10 |
2021-05-01 |
NCT04384250, RP:20.05.70 |
Phase Not Applicable |
Recruiting |
1 |
11 Months |
50 |
Ali Sobh, Ali Sobh, MD, Marwa Elnagdy, MD |
2020-05-14 |
| FALP-COVID: COVID-19-Convalescent Plasma for Treating Patients With Active Symptomatic COVID-19 Infection |
Coronavirus disease 19 infection |
convalescent plasma alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Arturo Lopez Perez Foundation |
Bolsa de Santiago, Confederation for Production and Commerce of Chile (CPC) |
Chile |
2020-04-07 |
2021-04-06 |
FALP 001-2020, FALP-COVID, NCT04384588 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
12 Months |
100 |
Christian Caglevic, MD, Christian Caglevic, md, Raimundo Gazitua, MD |
2020-05-14 |
| A clinical trial to study the efficacy of homeopathic medicine in prevention and cure of Coronavirus disease 19 |
Coronavirus disease 19 infection |
arsenic album 30 alone |
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Sai Nidan Homeopathic Clinic |
|
India |
2020-05-08 |
|
CTRI/2020/05/025049 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
100 |
DR ASHISH DUBEY, DR DHIRENDRA TIWARI |
2020-05-14 |
| Levamisole and Isoprinosine in the Treatment of COVID-19: A Proposed, Therapeutic Trial |
Coronavirus disease 19 infection |
isoprinosine plus levamisole |
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cairo University |
|
Egypt |
2020-05-05 |
2020-10-30 |
LEVAMISOLE AND ISOPRINOSINE, NCT04383717 |
Phase 3 Clinical |
Not yet recruiting |
1 |
5 Months |
60 |
Hagar El Sayed, Hagar El Sayed, MD, Mohamed El Darouti, Professor |
2020-05-14 |
| POCUS: Predicting Outcomes for Covid-19 Using Sonography |
Coronavirus disease 19 infection, Viral pneumonia |
lung ultrasound alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Stanford University |
|
US |
2020-03-21 |
2020-12-31 |
IRB-55621, NCT04384055, POCUS |
Phase Not Applicable |
Recruiting |
0 |
9 Months |
200 |
Andre D Kumar, MD, MEd |
2020-05-14 |
| H-Cov-Run: HDL Target of COVID-19 ? Analysis on the Caregivers of the Reunion University Hospital |
Coronavirus disease 19 infection |
blood sampling alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire de la Réunion |
|
France |
2020-05-31 |
2021-06-30 |
2020/CHU/08, H-Cov-Run, NCT04384705 |
Phase Not Applicable |
Not yet recruiting |
1 |
13 Months |
500 |
David COURET, PH, Lucie AUZANNEAU |
2020-05-14 |
| CovidSurg-Cancer: Outcomes of Elective Cancer Surgery During the COVID-19 Pandemic Crisis |
Breast tumor, Colorectal tumor, Coronavirus disease 19 infection, Esophagus tumor, Gynecological disorder, Liver tumor, Pancreas tumor, Sarcoma, Stomach tumor, Urinary tract tumor |
elective cancer surgery alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The University of Birmingham |
Christian Medical College and Hospital |
US, Ghana, Zambia, Philippines, Nigeria, UK, France, India, Pakistan, Benin, Italy, Rwanda, Australia, United Arab Emirates, Canada, Mexico, South Africa, Spain |
2020-03-30 |
2020-12-31 |
CSC-20200324, CTRI/2020/05/025160, CovidSurg-Cancer, NCT04384926 |
Phase Not Applicable |
Recruiting |
23 |
9 Months |
1000 |
Ana Minaya-Bravo, Aneel Bhangu, Arshad Rashid, Asif Mehraj, Dhruva Nath Ghosh, Dmitri Nepogodiev, Parvez David Haque, Rohin Mittal, Shyla Sree, Stanley Mathew, Vijay Pillai |
2020-05-14 |
| CoVideo: A short, animated video to improve COVID-19 hygiene uptake: an online randomized experiment with 20,000 participants |
Coronavirus disease 19 infection |
CoVideo alone, attention placebo control (PAC) video alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
University of Heidelberg |
Heidelberg Institute of Global Health, Stanford University |
Germany, France, US, Mexico, Spain, UK |
2020-05-31 |
|
55820, CoVideo, DRKS00021582 |
Phase Not Applicable |
Not yet recruiting |
5 |
|
20000 |
Alain Vandormael, Mr. Dr Till Barnighausen, Mr. Prof Dr Till Baernighausen, Ms. Dr Maya Adam |
2020-05-14 |
| CONNAITRE: COVID-19 In Tunisia: An Observational, Cross-Sectional, Registry Study |
Coronavirus disease 19 infection |
PCR test alone, TDR test alone, clinical examination alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ministère de la Santé |
Abderrahmane Mami Hospital, Dacima Consulting, Eshmoun Clinical Research Centre |
Tunisia |
2020-05-15 |
2020-07-15 |
CONNAITRE, ECC2020-07, NCT04384614 |
Phase Not Applicable |
Not yet recruiting |
1 |
2 Months |
400 |
Agnès Hamzaoui, Pr, Chokri Jeribi, Dr, Eshmoun Clinical Research Centre |
2020-05-14 |
| Advanced Endoscopy During COVID-19 |
Coronavirus disease 19 infection, Gastrointestinal disease |
endoscopic retrograde cholangiopancreatography alone, endoscopic ultrasound alone |
|
|
Al-Azhar University |
Helwan University, National Liver Institute, Egypt |
Egypt, US, Singapore |
2020-05-15 |
2020-09-01 |
GLOBAL-ENDO-COVID, NCT04385147 |
Phase Not Applicable |
Not yet recruiting |
2 |
3 Months |
250 |
Damien Tan, MBBS, MRCP, Mohamed Alboraie, MD, MRCP(UK), Shahzad Iqbal, MD |
2020-05-14 |
| PR-Covid-19: Clinical, Biological and Histological Pulmonary and Renal Damage Associated With the SARS-CoV-2 Syndrome in Patients Admitted in ICU |
Adult respiratory distress syndrome, Coronavirus disease 19 infection, Lung injury, Renal failure |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hopitaux Universitaires de Strasbourg |
|
France |
2020-04-27 |
2020-07-31 |
7815, NCT04385004, PR-Covid-19 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
320 |
Alexandra MONNIER, MD, Bruno MOULIN, MD, PhD, Ferhat MEZIANI, MD, PhD, Francis SCHNEIDER, MD, PhD, François SEVERAC, MD, Hamid MERDJI, MD, Julie HELMS, MD, Margaux DELLA CHIESA, MD, Michel MERTES, MD, PhD, Patrick OHLMANN, MD, PhD, Romain KESSLER, MD, PhD, Saïd CHAYER, PhD, HDR, Sophie CAILLARD, MD, PhD |
2020-05-14 |
| Convalescent Plasma for Patients With COVID-19 |
Coronavirus disease 19 infection, Dyspnea |
convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Henry Ford Health System |
|
US |
2020-05-04 |
2020-08-01 |
13807, NCT04385199 |
Phase 2 Clinical |
Recruiting |
0 |
2 Months |
30 |
Geneva Tatem, MD |
2020-05-13 |
| CoV-ICU Score, Intensive Care Unit, SARS-CoV-2 |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Bursa Yüksek İhtisas Eğitim Ve Araştırma Hastanesi |
|
Turkey |
2020-06-01 |
2020-08-31 |
BYIEAH-202005, NCT04383483 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
100 |
Ali ASAN, Associate professor, Ali Asan, MD, Erkan Sayan, MD |
2020-05-14 |
| Caards-1: Curosurf in Adult Acute Respiratory Distress Syndrome Due to COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia |
Curosurf alone, bronchial fibroscopy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Versailles University Hospital |
|
France |
2020-05-27 |
2021-01-30 |
Caards-1, NCT04384731, P20/06 |
Phase 2 Clinical |
Not yet recruiting |
1 |
8 Months |
20 |
Christophe LENCLUD, MD, Sandrine ROUX |
2020-05-14 |
| HYDROCYCLO: Clinical Study In Which Patients Are Randomized To Receive Hydroxychloroquine versus Cyclosporine - Hydroxychloroquine To Compare Their Efficacy In The Treatment Of COVID-19 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
ciclosporin, Novartis plus hydroxychloroquine |
Calcineurin inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Infanta Sofia |
|
Spain |
2020-05-07 |
|
2020-002123-11, HUIS-04-2020, HYDROCYCLO |
Phase 4 Clinical |
Recruiting |
1 |
|
280 |
Gemma María Mora Ortega, Gonzalo Serralta San Martín, Tatiana Cobo Ibañez |
2020-05-14 |
| Convalescent Plasma for Treatment of COVID-19: An Exploratory Dose Identifying Study |
Coronavirus disease 19 infection |
SARS-CoV-2 convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Karolinska University Hospital |
Danderyd Hospital, Karolinska Institutet |
Sweden |
2020-05-07 |
2020-12-31 |
CP2, NCT04384497 |
Phase 1/Phase 2 Clinical |
Recruiting |
2 |
7 Months |
50 |
Joakim Dillner, Joakim Dillner, MD, PhD, Johan Ursing, MD, PhD, Karl Hagman, MD |
2020-05-14 |
| Neuromuscular Electrical Stimulation in Patients With COVID-19 Associated Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
Neuromuscular Electrical Stimulation alone, Routine physical therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Turin |
Azienda Ospedaliero Universitaria San Luigi Gonzaga |
Italy |
2020-04-17 |
2020-07-31 |
ESC270320, NCT04382729 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
80 |
Chiara Busso, MD, Federica Gamna, MD, Marco Alessandro Minetto, MD, PhD, Sabrina Dal Fior, MD |
2020-05-14 |
| ELVIS COVID-19: Hypertonic Saline Nasal Irrigation and Gargling in Suspected or Confirmed COVID-19 |
Coronavirus disease 19 infection |
hypertonic saline nasal irrigation and gargling alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Edinburgh |
|
UK |
2020-05-01 |
2020-07-31 |
AC20042, ELVIS COVID-19, NCT04382131 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
405 |
Aziz Sheikh, Emma Ward, Kenny Scott |
2020-05-14 |
| A two-phase clinical trial to examine the sensitivity and specificity of COVID-19 Ag Respi-Strip test to detect COVID-19 infection |
Coronavirus disease 19 infection |
COVID-19 Ag Respi-Strip test alone |
|
|
Universite Libre de Bruxelles |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
|
|
2020-05-13 |
| COVID_REHAB: Rehabilitation for People With COVID-19 in ICU |
Coronavirus disease 19 infection, Respiratory distress syndrome |
Pulmonary and Motor Rehabilitation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Padova |
Azienda Ospedaliera Universitaria Integrata Di Verona, University Hospital Padova |
Italy |
2020-05-10 |
2020-09-30 |
COVID_REHAB, NCT04381338, UPADOVA_1 |
Phase Not Applicable |
Not yet recruiting |
2 |
4 Months |
92 |
Alessandra Del Felice, MD, PhD, Katia Donadello, MD, PhD |
2020-05-14 |
| Blind, placebo-controlled, adaptive, randomized clinical trial of the efficacy and safety of the drug Allokin-alpha, lyophilisate for the preparation of a solution for subcutaneous administration (LLC Alloferon, Russian Federation) as part of complex therapy in patients with mild or moderate coronovirus infection (COVID-19) |
Coronavirus disease 19 infection |
Allokin-alpha alone |
|
|
Alloferon |
|
Russian Federation |
2020-05-28 |
2024-12-31 |
ALO001 |
Phase 3 Clinical |
Status not specified |
2 |
55 Months |
206 |
|
2020-05-13 |
| IMPACT: Using blood plasma to develop passive immunity to coronavirus in Ecuador |
Coronavirus disease 19 infection |
convalescent plasma alone, standard care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universidad Tecnológica Equinoccial |
SalvarVidasEC |
Ecuador |
2020-03-11 |
2020-12-31 |
IMPACT, ISRCTN85216856 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
9 Months |
200 |
Dr Baldeon |
2020-05-14 |
| APLICOV-PC: Proof-of-Concept Study to Evaluate the Safety Profile of Plitidepsin in Patients With COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
plitidepsin alone |
Elongation factor 1 alpha 2 modulator, VEGF-1 receptor modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
PharmaMar SA |
Apices Soluciones, S.L. |
Spain |
2020-05-07 |
2020-11-30 |
2020-001993-31, APL-D-002-20, APLICOV-PC, NCT04382066 |
Phase 1 Clinical |
Recruiting |
3 |
6 Months |
27 |
Jesús Fortún, MD, José Barberán, MD, José Barberán, Md, Maria J Pontes, María A Fores, Vicente Estrada, MD |
2020-05-14 |
| SAM-COVID: Immunosupressive Treatment in COVID-19 Patients |
Coronavirus disease 19 infection, Macrophage activation syndrome |
immunoglobulin alone, steroid therapy alone, Variable regimens including anakinra , sarilumab , tocilizumab |
IL-6 receptor antagonist, Type I IL-1 receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Spanish Network for Research in Infectious Diseases |
Fundación Pública Andaluza Para La Gestión De La Investigación En Salud De Sevilla |
Spain |
2020-05-31 |
2020-05-31 |
FIS-INM-2020-03, NCT04382781, SAM-COVID |
Phase Not Applicable |
Recruiting |
1 |
|
500 |
Jesús Rodriguez-Baño, MD, PhD, Sánchez-Barriga |
2020-05-14 |
| SAVIORII: Study Assessing Vagus Nerve Stimulation in COVID-19 Respiratory Symptoms |
Coronavirus disease 19 infection, Dyspnea, Respiratory distress syndrome |
gammaCore Sapphire alone, standard of care alone, vagus nerve stimulation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Allegheny-Singer Research Inst |
Electrocore Inc |
US |
2020-05-08 |
2020-12-30 |
2020-132-AGH, NCT04382391, SAVIORII |
Phase Not Applicable |
Recruiting |
0 |
7 Months |
20 |
AHN Research Institute, Boyle Cheng, PhD, Clinical Trials Contact, Tariq Cheema, MD |
2020-05-14 |
| Combination of Recombinant Bacterial ACE2 Receptors-Like Enzyme of B38-CAP and Isotretinoin Could be Promising COVID-19 Infection and Lung Injury Preventing Drug Better Than Recombinant Human ACE2 |
Coronavirus disease 19 infection, Lung injury |
standard of care alone, isotretinoin plus rbACE2 |
Retinoic acid receptor agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Kafrelsheikh University |
|
Egypt |
2020-05-31 |
2020-09-30 |
COV-2019 TREATMENT THIS IS, NCT04382950 |
Phase 1 Clinical |
Not yet recruiting |
2 |
4 Months |
24 |
M.Sc. Mahmoud Elkazzaz, M.Sc.Biochemistry, M.Sc.Mahmoud Elkazzaz, M.Sc.Biochemistry, Mahmoud Ramadan mohamed Elkazzaz |
2020-05-14 |
| Novel Regimens in COVID-19 Treatment |
Coronavirus disease 19 infection |
Variable regimens including azithromycin , chloroquine (Alexoquine) , ivermectin , nitazoxanide |
Chloride channel modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tanta University |
|
Egypt |
2020-05-08 |
2030-12-01 |
NCT04382846, TANTA COVID TREATMENT |
Phase 3 Clinical |
Not yet recruiting |
1 |
126 Months |
80 |
Sherief Abd-Elsalam, ass. prof., sherief Abd-Elsalam, Ass. Prof. |
2020-05-14 |
| COVIDNOCHE: COVIDNOCHE Trial (HFNO Versus CPAP Helmet) in COVID-19 Pneumonia |
Coronavirus disease 19 infection, Hypoxia, Respiratory failure, Viral pneumonia |
helmet continuous positive airway pressure therapy alone, high flow nasal oxygen therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Pennsylvania |
|
US |
2020-05-31 |
2020-10-31 |
843124, COVIDNOCHE, NCT04381923 |
Phase Not Applicable |
Not yet recruiting |
0 |
5 Months |
200 |
Tim Gaulton, MD, MSc, Timothy Gaulton |
2020-05-13 |
| Co-infection Management in COVID-19 Critically Ill |
Coronavirus disease 19 infection, Viral pneumonia |
FilmArray Pneumonia test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Clinique Universitaires Saint-Luc, Universite Catholique de Louvain |
bioMerieux SA |
Belgium |
2020-03-23 |
2020-04-24 |
2019/14MAR/124, NCT04382092 |
Phase Not Applicable |
Completed |
1 |
1 Month |
32 |
Alexia VERROKEN, MD, PhD |
2020-05-13 |
| Ivermectin Effect on SARS-CoV-2 Replication in Patients With COVID-19 |
Coronavirus disease 19 infection |
ivermectin alone, standard care alone |
Chloride channel modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Laboratorios Phoenix SAICF |
|
Argentina |
2020-05-07 |
2020-06-30 |
IVM-AR-1, NCT04381884 |
Phase 2 Clinical |
Not yet recruiting |
1 |
1 Month |
45 |
Alejandro Krolewiecki, MD, Marcelo A Tinelli, MD, Mónica Lombardo, MD, Ricardo Valentini, MD |
2020-05-14 |
| Effect of Hydroxychloroquine on QTc Interval |
Coronavirus disease 19 infection |
hydroxychloroquine alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Sanjay Gandhi Postgraduate Institute of Medical Sciences |
|
India |
2020-05-18 |
|
CTRI/2020/05/025089 |
Phase Not Applicable |
Recruiting |
1 |
|
50 |
Dr Mohan Gurjar |
2020-05-13 |
| A Cross-sectional and Cohort Study of COVID-19 Patients With Post-discharge Dysfunction |
Coronavirus disease 19 infection, Respiratory disease |
aerobic exercise alone, airway clearance training alone, breathing training alone, chest activity training alone, health education and energy saving techniques alone, local lung dilation techniques alone, rehabilitation instruction program alone, resistance training alone, self-rehabilitation exercises alone, systematic rehabilitation treatment program alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Peking University Third Hospital |
|
China |
2020-03-10 |
2020-12-31 |
M20200421, NCT04382534 |
Phase Not Applicable |
Recruiting |
1 |
9 Months |
300 |
Yuanmingfei Zhang, Dr. |
2020-05-13 |
| ZILU-COV: Zilucoplan in Improving Oxygenation and Short- and Long-term Outcome of COVID-19 Patients With Acute Hypoxic Respiratory Failure |
Acute lung injury, Coronavirus disease 19 infection, Hypoxia, Respiratory failure |
prophylactic antibiotic therapy alone, standard of care alone, zilucoplan alone |
Complement C5 factor inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universitair Ziekenhuis Gent |
UCB SA |
Belgium |
2020-05-31 |
2021-09-30 |
NCT04382755, ZILU-COV, ZILU-COV |
Phase 2 Clinical |
Not yet recruiting |
9 |
16 Months |
81 |
Anja Delporte, Bart Lambrecht, MDPhD, Bart N. Lambrecht, Karolien Vanhove, MD, Nikolaas De Neve, MD, Wim MD Terryn |
2020-05-13 |
| COLCHI-COVID: Randomized clinical trial to investigate the efficacy of early administration of colchicine in patients > 70 years of age and at high risk of pulmonary complications such as coronavirus-associated pneumonia |
Coronavirus disease 19 infection, Lung disease, Viral pneumonia |
colchicine alone |
|
Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fundacion Instituto de Investigacion Marques de Valdecilla, IDIVAL |
|
Spain |
2020-05-06 |
|
2020-001603-16, COLCHI-COVID, COLCHI-COVID |
Phase 3 Clinical |
Recruiting |
1 |
|
1024 |
Maria del Mar Garcia, María del Mar García |
2020-05-13 |
| A phase III trial of BT-588 in Covid-19 patients |
Coronavirus disease 19 infection |
BT-588 alone |
|
|
Biotest AG |
|
|
|
|
|
Phase 3 Clinical |
Planned |
0 |
|
|
|
2020-05-12 |
| Study of GUDUCHI TABLET on healthy individuals to prevent covid 19 |
Coronavirus disease 19 infection |
guduchi alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Central Council for Research in Ayurvedic Sciences |
Ministry of Ayush |
India |
2020-05-20 |
|
CTRI/2020/05/025088 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
|
1200 |
Dr B vankatshwarlu, Dr K Anumol |
2020-05-14 |
| Covid-19 Infection and Pulmonary Distress Treatment With Zanubrutinib in Hospitalized Participants |
Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure |
supportive care treatment alone, zanubrutinib alone |
Btk tyrosine kinase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
BeiGene Co Ltd |
|
US |
2020-05-31 |
2020-09-30 |
BGB-3111-219, NCT04382586 |
Phase 2 Clinical |
Not yet recruiting |
0 |
4 Months |
52 |
BeiGene, Todd Zimmerman, MD |
2020-05-14 |
| Convalescent Plasma versus Human Immunoglobulin to Treat COVID-19 Pneumonia |
Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure, Viral pneumonia |
convalescent plasma alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centenario Hospital Miguel Hidalgo |
|
Mexico |
2020-05-06 |
2020-09-30 |
2020-A-10, NCT04381858 |
Phase 3 Clinical |
Recruiting |
1 |
4 Months |
500 |
Alejandro Castillo, MD, Jose Manuel Arreola Guerra, MD, MSc, PhD, Jose Manuel Arreola, MD,PhD, Lucila Martinez, MDPhD, Mario Gonzalez Gamez, MD, Victor Monroy, MD |
2020-05-14 |
| Observational, Cohort Study of Critically Ill Patients With Covid-19 in Sweden |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Vastmanland County Council (Landstinget) |
|
Sweden |
2020-03-26 |
2021-05-31 |
NCT04382417, REGIONVASTMANLAND |
Phase Not Applicable |
Recruiting |
2 |
14 Months |
100 |
Bjorn Sjostrom, M.D., Björn Sjöstrom, M.D., Erland Ostberg, M.D., Ph.D. |
2020-05-14 |
| ImmunoCOVID: Coronavirus Infection in Primary or Secondary Immunosuppressed Children and Adults |
Coronavirus disease 19 infection |
|
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Southampton NHS Foundation Trust |
Alder Hey Children's Hospital, Birmingham Children's Hospital NHS Foundation Trust, Bradford Royal Infirmary, Bristol Royal Hospital for Children, Cambridge University Hospitals NHS Foundation Trust, Cardiff and Vale University Health Board, East Lancashire Hospitals NHS Trust, Great North Children's Hospital, Great Ormond Street Hospital for Children NHS Foundation Trust, Imperial College Healthcare NHS trust, Leeds Children's Hospital, NHS Ayrshire And Arran, Norfolk and Norwich University Hospitals NHS Foundation Trust, Nottingham Children's Hospital, Oxford University Hospitals NHS Trust, Royal Alexandra Children's Hospital, Royal Hospital for Sick Children, Royal Manchester Children's Hospital, Royal Sussex County Hospital, Sheffield Children's NHS Foundation Trust, St George's University Hospitals NHS Foundation Trust, Swansea Bay University Health Board, The Royal Marsden NHS Trust, University College London Hospitals Charity, University Hospitals Coventry & Warwickshire NHS Trust |
UK |
2020-03-22 |
2021-03-21 |
ImmunoCOVID, NCT04382508, RHM CHI1061 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
1500 |
Hans de Graaf, MD |
2020-05-13 |
| High-Dose Inhaled Nitric Oxide for COVID-19 (ICU Patients) |
Coronavirus disease 19 infection, Respiratory failure |
nitric oxide alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The University Health Network |
|
|
2020-05-31 |
2020-12-31 |
20-5449, NCT04383002 |
Phase 1 Clinical |
Not yet recruiting |
0 |
7 Months |
20 |
Jennifer Lister |
2020-05-13 |
| SIDIACO-RETRO: Sitagliptin Treatment in Diabetic COVID-19 Positive Patients |
Coronavirus disease 19 infection, Non-insulin dependent diabetes, Respiratory failure, Viral pneumonia |
sitagliptin alone |
Dipeptidyl peptidase IV inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universita degli Studi di Milano |
Humanitas Hospital, Italy, IRCCS Policlinico San Matteo, Ospedale Papa Giovanni XXIII, Ospedale dell'Angelo, Universita Degli Studi di Pavia |
Italy |
2020-05-15 |
2020-08-15 |
5/2020, NCT04382794, SIDIACO-RETRO |
Phase Not Applicable |
Not yet recruiting |
2 |
3 Months |
200 |
Paolo Fiorina, MD, PhD, Teresa Letizia, Dr. |
2020-05-13 |
| A Phase II, Controlled Clinical Study Designed to Evaluate the Effect of ArtemiC in Patients Diagnosed With COVID-19 |
Coronavirus disease 19 infection |
ArtemiC alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
MGC Pharmaceuticals d.o.o |
|
Israel |
2020-05-08 |
2020-07-31 |
MGC-006, NCT04382040 |
Phase 2 Clinical |
Recruiting |
2 |
2 Months |
50 |
Ameer Elemy, Elias, Ilana Aloni, Jamil Muhsan, Nadia Lisovoder, Rubi Zomer |
2020-05-13 |
| HeSAcovid: Full versus prophylactic anticoagulation for the treatment of severe forms of Covid-19 |
Coronavirus disease 19 infection |
enoxaparin sodium alone, full heparinization alone, unfractionated heparin alone |
Low molecular weight heparin |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital of the Faculty of Medicine of Ribeirão Preto |
Conselho Nacional de Desenvolvimento Cientifico e Tecnologico - CNPq |
Brazil |
2020-05-30 |
|
30958120.2.0000.5440, CEP: 4.000.967, HeSAcovid, RBR-949z6v, U1111-1251-4283 |
Phase 2 Clinical |
Recruiting |
1 |
|
30 |
Carlos Henrique Miranda |
2020-05-14 |
| Evaluation of the efficacy and safety of pharmacological inhibition of bradykinin for the treatment of Covid-19 |
Coronavirus disease 19 infection |
CE-1145 alone, icatibant alone, standard care alone |
Bradykinin B2 receptor antagonist, Complement C1s subcomponent inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universidade Estadual de Campina |
Fundacao de Amparo a Pesquisa do Estado Sao Paulo |
Brazil |
2020-04-27 |
|
3.979.595, 30227920.9.0000.5404, RBR-5s2mqg, U1111-1250-1843 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
|
180 |
Lício Augusto Velloso |
2020-05-14 |
| Egyptian Initial Experience About 2019 Novel Corona Virus: Study of 48 Patients in Alexandria-Egypt Using Chest CT |
Chronic obstructive pulmonary disease, Coronavirus disease 19 infection, Immune disorder, Interstitial lung disease, Mycobacterium tuberculosis infection, Vascular disease |
CT scanning alone |
|
|
University of Alexandria |
|
Egypt |
2020-02-01 |
2020-05-01 |
IRB (00012098), FWA (00018699), NCT04382469 |
Phase Not Applicable |
Completed |
1 |
3 Months |
48 |
Ahmed Samir, MD |
2020-05-13 |
| CórdobaTrail: Inhaled Ibuprofen to Treat COVID-19 |
Coronavirus disease 19 infection, Lung injury, Respiratory disease, Viral pneumonia |
ibuprofen alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Quimica Luar srl |
CONICET, Ceprocor - Centro De Excelencia En Prod Y Procesos De Córdoba |
Argentina |
2020-05-01 |
2021-01-31 |
CórdobaTrail, DNL000004, NCT04382768 |
Phase 2 Clinical |
Recruiting |
1 |
9 Months |
40 |
Dante M Beltramo, PhD, Néstor H García |
2020-05-13 |
| Examination in COVID-19 pandemic: whether endoscopies really generate aerosol particles? |
Coronavirus disease 19 infection |
endoscopy alone, handheld particle counter model 3889 alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Oita San-ai Medical Center |
|
Japan |
2020-05-11 |
|
UMIN000040353 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
50 |
Ryota Sagami |
2020-05-13 |
| Safety and Efficacy of Hydroxychloroquine Associated With Azythromycin in SARS-Cov-2 Virus |
Coronavirus disease 19 infection |
hydroxychloroquine alone, proper COVID19 treatment alone, azithromycin plus hydroxychloroquine |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
EMS SA, Hospital do Coracao |
|
Brazil |
2020-03-30 |
|
3.934.659, 30161220.0.1001.0060, RBR-9d8z6m |
Phase 3 Clinical |
Recruiting |
1 |
|
630 |
Fernando Godinho Zampieri |
2020-05-13 |
| Study of Efficacy and Safety of DV-890 in Patients With COVID-19 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
DFV-890 alone, standard of care (SOC) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Novartis AG |
|
|
2020-05-15 |
2020-07-29 |
2020-001870-32, CDFV890D12201, NCT04382053 |
Phase 2 Clinical |
Not yet recruiting |
0 |
2 Months |
120 |
Novartis Pharmaceuticals, Novartis pharmaceuticals |
2020-05-13 |
| GA and COVID19: Potential Role of Gum Arabic as Immunomodulatory Agent Among COVID 19 Patients |
Coronavirus disease 19 infection |
Acacia senegal gum arabic intake alone |
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Al-Neelain University |
University of Khartoum |
Sudan |
2020-06-01 |
2020-09-01 |
GA and COVID19, GA& COVID19, NCT04381871 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
2 |
3 Months |
110 |
Dr Babiker, PhD, Lamis Kaddam, Moawia M Mukhtar, PhD, Mustafa KM Nimeiri, MD, Shahenaz Satti, MSc |
2020-05-14 |
| Factors influencing psychological response among healthcare workers during 2020 COVID-19 pandemic |
Coronavirus disease 19 infection, Psychiatric disorder |
|
|
|
Sultan Haji Ahmad Shah Hospital |
|
Malaysia |
2020-05-18 |
2020-09-14 |
54947, NMRR-20-899-54947 |
Phase Not Applicable |
Status not specified |
1 |
3 Months |
|
Dr Ahmad Ashraf Ilman bin Zulbahri |
2020-05-13 |
| Vertical Transmission, COVID-19, Clinical Characteristics, Outcomes, Mothers, Neonates |
Coronavirus disease 19 infection |
|
|
|
Hospital Sungai Buloh |
|
Malaysia |
2020-05-11 |
2020-11-16 |
54821, NMRR-20-894-54821 |
Phase Not Applicable |
Status not specified |
1 |
6 Months |
|
Dr Lee Yee Leng, Dr See Kwee Ching |
2020-05-13 |
| COVIDIMMUNOPSY: Immunity and Infections in the Psychiatric Population |
Coronavirus disease 19 infection, Psychiatric disorder |
serological COVID testing alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assistance Publique Hopitaux de Paris |
INSERM |
|
2020-05-10 |
2020-06-25 |
APHP200553, COVIDIMMUNOPSY, NCT04381845 |
Phase Not Applicable |
Not yet recruiting |
0 |
1 Month |
200 |
France GUYOT |
2020-05-14 |
| Nurses Mental Healh_COVID-19 |
Coronavirus disease 19 infection, Psychiatric disorder |
|
|
|
University of Malaya |
|
Malaysia |
2020-05-15 |
2020-12-15 |
54719, NMRR-20-890-54719 |
Phase Not Applicable |
Not yet recruiting |
1 |
7 Months |
|
Dr. Chui Ping Lei |
2020-05-13 |
| A phase I trial of COVI-SHIELD to potentially treat COVID-19 |
Coronavirus disease 19 infection |
COVI-SHIELD alone |
COVID19 Spike glycoprotein inhibitor |
|
Sorrento Therapeutics Inc |
Mount Sinai Health System |
|
2020-09-30 |
|
|
Phase 1 Clinical |
Planned |
0 |
|
|
|
2020-05-13 |
| Hydroxychloroquine in SARS-CoV-2 (COVID-19) Pneumonia Trial |
Acute lung injury, Coronavirus disease 19 infection, Hypoxia, Respiratory distress syndrome, Viral pneumonia |
hydroxychloroquine alone, usual care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kootenai Health |
Washington State University |
US |
2020-05-31 |
2022-06-01 |
18244, NCT04382625 |
Phase 4 Clinical |
Not yet recruiting |
0 |
24 Months |
120 |
Jeanette Berg, MD, PhD, John Roll, PhD, Sandra Albritton, MN,RN, Sean Cook, D.O., Shamela Barnett, Sterling McPherson, PhD |
2020-05-13 |
| The Impact of COVID-19 Pandemic on Cancer Care |
Cancer, Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
El Zaitoun Specialized Hospital |
|
Egypt |
2020-05-23 |
2020-07-31 |
CANCER CARE DURING COVID-19, NCT04382495 |
Phase Not Applicable |
Not yet recruiting |
1 |
2 Months |
200 |
Aalaa Abdou, Dr, Aalaa Abdou, MSc |
2020-05-14 |
| COVID-Impact: Impact of COVID-19 on Mental Health of Health Care Workers |
Coronavirus disease 19 infection, Psychiatric disorder |
|
|
Healthy volunteers accepted |
Universitair Ziekenhuis Gent |
|
Belgium |
2020-04-17 |
2022-12-31 |
BC-07564, COVID-Impact, NCT04382196 |
Phase Not Applicable |
No longer recruiting |
1 |
32 Months |
497 |
Gilbert Lemmens |
2020-05-14 |
| Safety and Efficacy of NP-120 (Ifenprodil) for the Treatment of Confirmed COVID-19 Infected Hospitalized Patients |
Coronavirus disease 19 infection |
repurposed ifenprodil (oral, IPF/UC/IBD/crohn's disease/cough), Nash Pharmaceuticals alone, standard of care alone |
NMDA receptor epsilon 2 subunit inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Algernon Pharmaceuticals |
Novotech (Australia) Pty Ltd |
|
2020-07-31 |
2022-02-28 |
AGN120-3, NCT04382924 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
0 |
19 Months |
462 |
Mark Williams, Ph.D., Nancy Stewart, Ph.D. |
2020-05-14 |
| Treatment of Covid-19 Associated Pneumonia With Allogenic Pooled Olfactory Mucosa-derived Mesenchymal Stem Cells |
Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia |
allogenic pooled olfactory mucosa-derived mesenchymal stem cells alone, standard treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus |
Belarusian State Medical University |
Belarus |
2020-05-11 |
2021-06-30 |
IBCE_MSC2(COVID), NCT04382547 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
13 Months |
40 |
Andrei Y Hancharou, Dr., Eduard A Dotsenko, Dr., prof., Natalia G Antonevich, Dr. |
2020-05-14 |
| A Study of Hydroxychloroquine versus Placebo to Prevent COVID-19 Infection in Patients Receiving Radiotherapy |
Breast tumor, Central nervous system tumor, Coronavirus disease 19 infection, Gastrointestinal tumor, Gynecological disorder, Head and neck tumor, Lung tumor, Prostate tumor, Skin cancer |
hydroxychloroquine alone, standard radiation therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Memorial Sloan-Kettering Cancer Center |
|
US |
2020-05-07 |
2021-05-31 |
20-176, NCT04381988 |
Phase 2 Clinical |
Recruiting |
0 |
12 Months |
132 |
Nancy Lee, MD, Yao Yu, MD |
2020-05-14 |
| MAS-COVID: Study of Efficacy and Safety of MAS-825 in Patients With COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
MAS-825 alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Novartis AG |
|
|
2020-05-15 |
2020-11-05 |
CMAS825F12201, MAS-COVID, NCT04382651 |
Phase 2 Clinical |
Not yet recruiting |
0 |
5 Months |
120 |
Novartis Pharmaceuticals |
2020-05-14 |
| WARd-COVID: Non-invasive Ventilatory Support of Patients Affected by COVID-19 |
Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia |
continuous positive airway pressure therapy alone, high-flow nasal cannula therapy alone, non-invasive ventilation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Milano-Bicocca |
|
Italy |
2020-03-26 |
2020-06-30 |
NCT04382235, WARD-COVID, WARd-COVID |
Phase Not Applicable |
No longer recruiting |
34 |
3 Months |
900 |
|
2020-05-14 |
| An accelerated phase II study of BT-588 in COVID-19 patients |
Coronavirus disease 19 infection |
BT-588 alone |
|
|
Biotest AG |
|
|
|
|
|
Phase 2 Clinical |
Planned |
0 |
|
|
|
2020-05-12 |
| ATOMIC2: A Multicenter, Open-label, Two-arm, Randomized, Superiority Clinical Trial of Azithromycin Versus Usual Care In Ambulatory COVID-19 |
Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia |
standard usual care alone, azithromycin plus paracetamol |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Oxford |
Pfizer Inc |
|
2020-05-13 |
2020-10-13 |
20/HRA/2105, 2020-001740-26, 282892, ATOMIC2, ATOMIC2, NCT04381962 |
Phase 3 Clinical |
Not yet recruiting |
0 |
5 Months |
800 |
Lucy Cureton, Paul Little, MD PhD, Timothy SC Hinks, MD PhD |
2020-05-14 |
| COUP19: COVID-19 associated neuropathy and myopathy in Germany |
Coronavirus disease 19 infection, Myopathy, Neuropathy |
neurological and neuropyhsiological examination alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Bergmannsheil, Bochum |
University of Wurzburg, Universitätsklinikum Schleswig-Holstein |
Germany |
2020-07-01 |
|
20-6925, COUP19, DRKS00021677 |
Phase Not Applicable |
Not yet recruiting |
3 |
|
200 |
Elena Enax-Krumova, Mr. Prof. Dr. Ralf Baron, Ms. Dr. Christine Meyer-Frießem, Ms. Jun. Prof. Dr. Elena Enax-Krumova, Ms. PD Dr. Janne Gierthmühlen, Ms. Prof. Dr. Claudia Sommer, Ms. Prof. Dr. Nurcan Üçeyler, Universitätsklinikum Bergmannsheil gGmbH |
2020-05-13 |
| lnfluence of the COVID-19-pandemic on the treatment of ENT patients |
Coronavirus disease 19 infection |
|
|
|
Universitats-Augenklinik Freiburg |
|
Germany |
2020-05-12 |
|
302/20, DRKS00021699, U1111-1251-7604 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
20000 |
Sarah Riemann |
2020-05-13 |
| Ventilation@MPI: Retrospective analysis of the relationship between invasive ventilation (considering COVID-19) and a Comprehensive Geriatric Assessment (CGA) |
Coronavirus disease 19 infection, Lung disease, Viral pneumonia |
|
|
Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital of Cologne |
|
Germany |
2020-04-17 |
2020-04-30 |
20-1179, DRKS00021638, Ventilation@MPI |
Phase Not Applicable |
Completed |
1 |
|
1276 |
Maria Cristina Polidori Nelles |
2020-05-13 |
| Norwegian SARS-CoV-2 Study - Virological, Clinical and Immunological Characterisation of COVID-19 |
Coronavirus disease 19 infection |
SARS-CoV-2 PCR alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Oslo University Hospital |
Haukeland University Hospital, Ostfold Hospital Trust, St Olavs Hospital, University Hospital of North Norway, University Hospital, Akershus, Vestre Viken HF |
Norway |
2020-03-02 |
2023-12-31 |
20-04072, NCT04381819 |
Phase Not Applicable |
Recruiting |
7 |
45 Months |
1000 |
Anders B Kildal, PhD, Bjørn Blomberg, PhD, Christian Prebensen, PhD, Erik Solligård, PhD, Fredrik G Müller, Professor, Jan C Holter, PhD, Jonas Bergan, phd, Lars Heggelund, PhD, Susanne G Dudman, Ass.Professor, Susanne G Dudman, PhD, Susanne G Dudman, Professor |
2020-05-13 |
| Hydroxychloroquine in patients with mild COVID-19 illness with risk factors for severe disease |
Coronavirus disease 19 infection |
hydroxychloroquine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
All India Institute of Medical Sciences |
|
India |
2020-05-06 |
|
CTRI/2020/05/025022 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
166 |
Dr Manish Soneja |
2020-05-13 |
| A Medical Records Based Study for Clinical Efficacy and Safety of 'clear lung detoxification soup' in the treatment of Novel Coronavirus Pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Qingfei Paidu Decoction alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences |
National Science and Technology Support Plan of the People's Republic of China |
China |
2020-01-27 |
2020-07-27 |
ChiCTR2000032767 |
Phase Not Applicable |
No longer recruiting |
13 |
6 Months |
782 |
Shi Nannan, Wang Yanping |
2020-05-13 |
| Low-Dose Anti-inflammatory Radiotherapy for the Treatment of Pneumonia by COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
low-dose radiotherapy (0.5 Gy) alone, Variable regimens including Dolquine , azithromycin , dexamethasone , heparin , lopinavir + ritonavir , methylprednisolone , oxygen , prednisone , tocilizumab (intravenous), Roche/Chugai |
HIV protease inhibitor, IL-6 receptor antagonist, IL-6 receptor modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Grupo de Investigación Clínica en Oncología Radioterapia |
Hospital Universitari Sant Joan de Reus, Hospital Universitario Madrid Sanchinarro, Hospital del Mar |
Spain |
2020-05-08 |
2021-07-01 |
IPACOVID, NCT04380818 |
Phase 2 Clinical |
Recruiting |
3 |
13 Months |
106 |
ANGEL MONTERO, Md, PhD, Angel Montero, MD, PhD, MANEL ALGARA, MD, PhD, MERITXELL ARENAS, MD, PhD, Manel Algara, MD, PhD, Merirxell Arenas, MD, PhD |
2020-05-12 |
| Prevalence of Severe Bleeding in COVID-19 Patients Treated With Higher Than Recommended Thromboprophylaxis Doses |
Bleeding, Coronavirus disease 19 infection |
thromboprophylaxis therapy alone |
|
|
Foundation for the study of VTE diseases (FUENTE) |
|
Spain |
2020-04-13 |
2025-06-13 |
BLEEDING042020, NCT04380779 |
Phase Not Applicable |
Recruiting |
1 |
62 Months |
5000 |
Manuel Monreal, Mayra Hawkins |
2020-05-12 |
| A Pilot Study Evaluating the Effect of NT-17, a Long Acting Interleukin-7, to Enhance Immune Clearance of SARS-CoV-2(COVID-19) |
Coronavirus disease 19 infection |
HyLeukin-7 alone, supportive care alone |
IL-7 receptor agonist, Interleukin-7 ligand |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Washington University School of Medicine, US |
|
US |
2020-07-31 |
2021-02-28 |
04-20-20-CAMPIAN, NCT04380948 |
Phase 1 Clinical |
Not yet recruiting |
0 |
7 Months |
30 |
Erik R Dubberke, M.D., MSPH, Jian Campian, M.D., Ph.D., Jingqin (Rosy) Luo, Ph.D. |
2020-05-13 |
| A 6-week, controlled, two-arm randomized study of molecular iodine for protecting healthcare workers from COVID-19 exposure |
Coronavirus disease 19 infection |
CDC guidelines alone, ioCleanse Hand Cleanser alone, ioMist Nasal Spray alone, ioRinse Oral Rinse alone |
|
|
Iotech International Llc |
|
US |
|
|
|
Phase Not Applicable |
Recruiting |
0 |
|
300 |
Dr. Hillel Ephros |
2020-05-11 |
| Efficacy and Safety of Polyoxidonium in Hospitalized Patients With Coronavirus Disease COVID-19 |
Coronavirus disease 19 infection |
Polyoxidonium alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
NPO Petrovax Pharm LLC |
|
Russian Federation |
2020-04-29 |
2021-04-30 |
NCT04381377, PО-COV-III-20 |
Phase 2/Phase 3 Clinical |
Recruiting |
12 |
12 Months |
394 |
A. A. Grebenyuk, A. A. Ploskireva, A. S. Pankov, D. A. Lioznov, D. N. Protsenko, E. G. Tikhomolova, I. G. Gordeev, I. G. Sitnikov, Jean-Francois Rossi, Professor, L. V. Kolobukhina, M. V. Smirnov, Nikolay Dodonov, S. K. Zyryanov, V. V. Kulabukhov |
2020-05-12 |
| HALT COVID-19: Inhalation of Ciclesonide for Patients With COVID-19: A Randomized, Open Treatment Study |
Coronavirus disease 19 infection |
ciclesonide (metered dose inhaler), Teijin/Covis/AstraZeneca alone |
Glucocorticoid receptor agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Capio Saint Göran's Hospital |
Danderyd Hospital, Karolinska University Hospital, Vasteras Central Hospital |
Sweden |
2020-05-15 |
2020-12-31 |
2020-02183, HALT COVID-19, NCT04381364 |
Phase 2 Clinical |
Not yet recruiting |
4 |
7 Months |
446 |
Anders Krifors, MD, Daniel Brodin, MD, Daniel P Andersson, MD, PhD, Magnus Bager, MD, Ola Blennow, MD, PhD |
2020-05-13 |
| Emergency Ventilator Splitting Between Two or More Patients (COVID-19) |
Coronavirus disease 19 infection |
emergency ventilator splitter alone, oxygen therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Stanford University |
|
US |
2020-05-31 |
2020-06-30 |
55989, NCT04381013 |
Phase Not Applicable |
Not yet recruiting |
0 |
1 Month |
4 |
Joseph Woo, MD |
2020-05-13 |
| STATCO19: Atorvastatin in COVID-19 |
Coronavirus disease 19 infection |
atorvastatin alone |
HMG CoA reductase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Mount Auburn Hospital |
|
|
2020-05-08 |
2022-05-08 |
MOUNTAUBURN, NCT04380402, STATCO19 |
Phase 2 Clinical |
Not yet recruiting |
0 |
24 Months |
300 |
|
2020-05-12 |
| Asymptomatic novel coronavirus pneumonia (COVID-19) patients Have Longer Treatment Cycle Than Mild and Moderate Patients: a medical records based study |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The Science and Technology Department of Guizhou Province |
|
China |
2020-01-29 |
2020-03-31 |
ChiCTR2000032770 |
Phase 0 Clinical |
Completed |
1 |
2 Months |
52 |
Wei Zhang |
2020-05-12 |
| Co-Stars: COVID-19 Staff Testing of Antibody Responses Study |
Coronavirus disease 19 infection |
serological testing alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Great Ormond Street Hospital for Children NHS Foundation Trust |
|
UK |
2020-04-27 |
2026-07-27 |
20CB17, Co-Stars, NCT04380896 |
Phase Not Applicable |
Recruiting |
1 |
75 Months |
1000 |
Louis Grandjean, Dr, Vanshree Patel, Dr |
2020-05-12 |
| Correlation between novel coronavirus pneumonia (COVID-19) and mental health of breast cancer patients: a cross-sectional study in Hunan Province |
Coronavirus disease 19 infection, Psychiatric disorder |
|
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Xiangya Hospital Of Central South University |
Hunan Provincial Natural Science Foundation |
China |
2020-01-01 |
|
ChiCTR2000032768 |
Phase Not Applicable |
Completed |
1 |
|
309 |
Ling Wang |
2020-05-11 |
| Clinical efficacy of Nafamostat for COVID-19 pneumonia |
Coronavirus disease 19 infection, SARS coronavirus infection |
Nafamostat alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Gyeongsang National University Hospital |
Ministry of Science and ICT |
South Korea |
2020-05-25 |
|
GNUH-2020-04-012, KCT0005003 |
Phase 2 Clinical |
Not yet recruiting |
7 |
|
84 |
In-Gyu Bae |
2020-05-12 |
| PanCOVID: Covid-19 Pandemic and Pancreatic Surgery in Italy |
Coronavirus disease 19 infection, Pancreas tumor |
pancreatic surgery alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fondazione Policlinico Universitario Agostino Gemelli IRCCS |
|
Italy |
2019-01-01 |
2020-06-30 |
FPGEMELLIIRCCS, NCT04380766, PanCOVID |
Phase Not Applicable |
Recruiting |
1 |
18 Months |
700 |
Sergio Alfieri, Sergio Alfieri, MD |
2020-05-13 |
| Effectiveness and Safety of Convalescent Plasma Therapy on COVID-19 Patients With Acute Respiratory Distress Syndrome |
Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia |
convalescent plasma alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Indonesia |
Dr Cipto Mangunkusumo General Hospital, Faculty of Medicine, University of Indonesia |
Indonesia |
2020-05-11 |
2020-08-31 |
CONVALESCENT PLASMA RSCM-FKUI, NCT04380935 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
3 |
3 Months |
60 |
Andri MT Lubis, MD, PhD, Andri Maruli Tua Lubis, Cosphiadi Irawan, MD, PhD, Elida Marpaung, MD, MBiomed, Lugyanti Sukrisman, MD, PhD, Robert Sinto, MD, Siti Rizny F Saldi, Pharm, MSc, William Djauhari, MD |
2020-05-12 |
| Evaluation of BCG as potential therapy for COVID-19 |
Coronavirus disease 19 infection |
BCG alone |
|
Young Adults (18-44 yrs) |
Haffkine Biopharmaceutical Corporation Ltd., Medical Education and Drugs Department |
|
India |
2020-05-06 |
|
BIO/CT/20/000049, CTRI/2020/05/025013 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
60 |
Dr Rajesh Deshmukh, Dr Sanjay Mukherjee, Dr Sonali Salvi, Dr Usha Padmanabhan |
2020-05-11 |
| Evaluation of the effect of jujube product on Covid-19 patients |
Coronavirus disease 19 infection |
jujube alone, routine protocol alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Semnan University of Medical Sciences |
|
Iran |
2020-05-09 |
|
IR.SEMUMS.REC.1399.032, IRCT20171213037866N2 |
Phase 3 Clinical |
Recruiting |
1 |
|
68 |
Ali Gohari, Nasim Behnoud, Parviz Kokhaie |
2020-05-12 |
| The effectiveness of educational-treatment package based on psychological flexibility in burnout, quality of working life, work-family conflict and mental health |
Coronavirus disease 19 infection |
training package alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Isfahan University of medical Sciences |
|
Iran |
2020-05-04 |
|
IR.MUI.MED.REC.1399.026, IRCT20200413047052N1 |
Phase Not Applicable |
Recruiting |
1 |
|
60 |
Amrolla Ebrahimi, Amrullah Ebrahimi, Sayed Mohammad Hosein Mosavi |
2020-05-12 |
| Study for the Use of the IL-6 Inhibitor Clazakizumab in Patients With Life-threatening COVID-19 Infection |
Coronavirus disease 19 infection, Lung failure, Respiratory distress syndrome |
clazakizumab alone |
IL-6 receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Columbia University |
NYU Langone Health, Vitaeris Inc |
US |
2020-05-31 |
2020-08-01 |
AAAT0142, NCT04381052 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
0 |
2 Months |
30 |
David J Cohen, MD, David J. Cohen, MD, Melanie Foley |
2020-05-13 |
| A phase III study of EDP-1815 for the treatment of COVID-19 infection |
Coronavirus disease 19 infection |
EDP-1815 alone |
|
|
Evelo Biosciences Inc |
|
|
|
|
|
Phase 3 Clinical |
Planned |
0 |
|
|
|
2020-05-11 |
| Describing Chinese Herbal Medicine Telehealth Care for Symptoms Related to Infectious Diseases Such as COVID-19 |
Coronavirus disease 19 infection |
Chinese herbal medicine (Spring Wind Herb Company) alone, telehealth care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Center for Integrated Care |
University of California San Francisco, University of Utah |
US |
2020-04-11 |
2025-04-11 |
01-04-20, NCT04380870 |
Phase Not Applicable |
Recruiting |
0 |
60 Months |
500 |
Katherine Taromina, Katherine Taromina, DACM, Lee Hullender Rubin, DAOM, Lee Hullender Rubin, DOAM, Lisa A Conboy, ScD, Lisa Taylor-Swanson, PhD |
2020-05-13 |
| A phase II, double-blind, placebo-controlled study to assess the safety and efficacy of EDP-1815 for the treatment of hospitalized patients with newly diagnosed COVID-19 |
Coronavirus disease 19 infection |
EDP-1815 alone, standard of care alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Evelo Biosciences Inc, Robert Wood Johnson University Hospital, Rutgers University |
|
US |
2020-12-31 |
|
EDP1815-205 |
Phase 2 Clinical |
Planned |
0 |
|
60 |
Reynold A. Panettieri, Jr., M.D |
2020-05-14 |
| MiRCOVID: Noncoding RNAs in COVID-19 and COVID-19 Related Kidney Dysfunction |
Coronavirus disease 19 infection, Renal injury |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Heinrich Heine Universitat Dusseldorf |
|
Germany |
2020-04-16 |
2021-07-31 |
1, MiRCOVID, NCT04381351 |
Phase Not Applicable |
Recruiting |
1 |
15 Months |
50 |
Dr. Timo Brandenburger, Timo Brandenburger, MD |
2020-05-14 |
| Predi-COVID: Luxembourg Cohort of Positive Patients for COVID-19: a Stratification Study to Predict Patient Prognosis |
Coronavirus disease 19 infection |
biological sampling alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Luxembourg Institute of Health |
Centre Hospitalier de Luxembourg, Hopitaux Robert Schuman (Luxembourg), Laboratoire National de santé, Universite of Luxembourg |
Luxembourg |
2020-05-04 |
2021-12-31 |
NCT04380987, PREDI-COVID, Predi-COVID |
Phase Not Applicable |
Recruiting |
1 |
19 Months |
200 |
Aurelie Fischer, MS, Laetitia Huiart, MD, PhD, Manon Gantenbein, PhD |
2020-05-14 |
| Changes in the Consumption of Psychoactive Substances During Containment Linked to COVID-19 |
Coronavirus disease 19 infection |
psychoactive substances alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital, Montpellier |
|
France |
2020-05-01 |
2020-08-01 |
NCT04380714, RECHMPL20-0273 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
700 |
Aurélie Mieuset, MD, Aurélie Mieuset, PhD |
2020-05-14 |
| Oral Health and Psychosocial Factors During the COVID-19 Pandemic |
Coronavirus disease 19 infection, Periodontitis, Psychiatric disorder |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Heidelberg |
|
Germany |
2020-05-08 |
2020-07-31 |
NCT04381273, S-303/2020 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
1000 |
Antonio Ciardo, Dr. |
2020-05-12 |
| Study to Evaluate the Safety and Efficacy of Prolastin in Hospitalized Patients with Coronavirus Disease (COVID-19) |
Coronavirus disease 19 infection |
Prolastin alone, Standard Medical Treatment alone |
Alpha 1 proteinase inhibitor, Serine protease inhibitor |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Grifols SA |
|
Spain |
2020-05-08 |
|
2020-001953-36, GC2005 |
Phase 2 Clinical |
Recruiting |
1 |
|
100 |
Department of Clinical Trials |
2020-05-13 |
| Efficacy and safety study of IVIG in hospitalized subjects with COVID-19 |
Coronavirus disease 19 infection |
Flebogamma 10% DIF alone, Flebogamma DIF 5% alone, Standard Medical Treatment (SMT) alone |
Beta amyloid modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Grifols SA |
|
Spain |
2020-05-08 |
|
2020-001696-32, GC2004 |
Phase 2 Clinical |
Recruiting |
1 |
|
100 |
Department of Clinical Trials |
2020-05-13 |
| Study of the efficacy of ivermectin in the treatment and prevention of COVID-19 |
Coronavirus disease 19 infection |
ivermectin alone |
Chloride channel modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fundació Recerca Mútua Terrassa (FMT) |
|
Spain |
2020-05-06 |
|
2020-001994-66, ECIT-PRO19 |
Phase 3 Clinical |
Recruiting |
1 |
|
266 |
Clinical trial |
2020-05-13 |
| Tableted COVID-19 Therapeutic Vaccine (COVID-19) |
Coronavirus disease 19 infection |
V-SARS alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Immunitor LLC |
Immunitor Inc |
Canada |
2020-06-15 |
2021-06-15 |
IMM24, NCT04380532 |
Phase 1/Phase 2 Clinical |
Recruiting |
1 |
12 Months |
20 |
Aldar Bourinbaiar, MD/PhD, Allen Bain, PhD |
2020-05-12 |
| GLUCOCOVID: Use of corticosteroids in patients with sars-cov2 coronavirus infection |
Coronavirus disease 19 infection |
Urbason alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fundacion Instituto de Investigacion Marques de Valdecilla, IDIVAL |
|
Spain |
2020-05-07 |
|
2020-001934-37, GLUCOCOVID, GLUCOCOVID |
Phase 4 Clinical |
Recruiting |
1 |
|
200 |
Mar García Sáiz |
2020-05-13 |
| COVIDADOMEVA: Risk Factors Worsening COVID-19 for Out-patient With Home Monitoring |
Coronavirus disease 19 infection |
|
|
|
University Hospital, Grenoble |
|
France |
2020-05-15 |
2020-12-30 |
2020-A01040-39, 38RC20.135, COVIDADOMEVA, NCT04380662 |
Phase Not Applicable |
Not yet recruiting |
1 |
7 Months |
1000 |
Guillaume DEBATY, PhD, Olivier EPAULARD, PhD, Sandra DAVID-TCHOUDA, MD, Sandrine MASSICOT, Master |
2020-05-12 |
| Pilot study to evaluate the potential of ivermectin to reduce COVID-19 transmission |
Coronavirus disease 19 infection |
ivermectin alone |
Chloride channel modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Clinica Universidad de Navarra |
|
Spain |
2020-05-07 |
|
2020-001474-29, SAINT |
Phase 2 Clinical |
Recruiting |
1 |
|
24 |
UCEC |
2020-05-13 |
| ACHIEVE: Clarithromycin in COVID-19 |
Coronavirus disease 19 infection |
clarithromycin alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hellenic Institute for the Study of Sepsis |
|
Greece |
2020-05-07 |
|
2020-001882-36, ACHIEVE, ACHIEVE |
Phase 2 Clinical |
No longer recruiting |
1 |
|
90 |
President of the Board |
2020-05-13 |
| A trial to compare standard of care (SOC) alone with SOC plus hydroxychloroquine or SOC with a combination of hydroxycholorquine and azithromysin in the treatment of coronovirus |
Coronavirus disease 19 infection |
azithromycin alone, hydroxychloroquine alone, standard of care alone, azithromycin plus hydroxychloroquine |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University College Dublin |
|
Ireland |
2020-05-05 |
|
2020-001265-36, UCDCRC/20/01 |
Phase 4 Clinical |
No longer recruiting |
1 |
|
267 |
QRAM |
2020-05-13 |
| COVID-OLD: Direct and Indirect Impact of COVID-19 In Older Populations |
Coronavirus disease 19 infection |
|
|
Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital, Grenoble |
|
France |
2020-04-09 |
2021-10-09 |
2020-A00846-33, 38RC20.118, COVID-OLD, NCT04381312 |
Phase Not Applicable |
Recruiting |
1 |
18 Months |
1000 |
Gaetan GAVAZZI, Pr, Gaëtan Gavazzi, PhD Professor, Saber Touati, ARC |
2020-05-12 |
| A randomized, double-blind, placebo-controlled clinical trial to assess whether hydroxychloroquine and azithromycin reduce hospitalization and/or death in individuals suffering from COVID-19 |
Coronavirus disease 19 infection |
azithromycin alone, hydroxychloroquine alone |
|
|
National Institutes of Health |
|
US |
|
|
|
Phase Not Applicable |
Recruiting |
0 |
|
2000 |
Eric Daar |
2020-05-12 |
| A clinical trial of CERC-002 for potential treatment of Acute Respiratory Distress Syndrome (“ARDS”) and Acute Lung Injury (“ALI”) in hospitalized COVID-19 patients |
Acute lung injury, Coronavirus disease 19 infection, Respiratory distress syndrome |
CERC-002 alone |
Tumor necrosis factor 14 ligand inhibitor |
|
Cerecor Inc |
|
|
|
|
|
Phase Not Applicable |
Recruiting |
0 |
|
|
|
2020-05-11 |
| COVID-19 HOPE Study: A clinical study to assess AT-H201 in the treatment of subjects with COVID-19 infection |
Coronavirus disease 19 infection |
AT-H201 alone |
|
|
Atossa Genetics Inc |
|
US |
|
|
COVID-19 HOPE Study |
Phase Not Applicable |
Not yet recruiting |
0 |
|
|
|
2020-05-11 |
| A Study to Evaluate the Efficacy and Safety of Sirukumab in Confirmed Severe or Critical Confirmed Coronavirus Disease (COVID)-19 |
Coronavirus disease 19 infection |
sirukumab alone, standard of care (SOC) alone |
IL-6 receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Janssen Pharmaceutica NV |
|
US |
2020-04-24 |
2020-09-16 |
CNTO136COV2001, CR108820, NCT04380961 |
Phase 2 Clinical |
Recruiting |
0 |
4 Months |
270 |
Study Contact |
2020-05-14 |
| SCREENING: Prevalence of DVT or PE in Patients Infected With COVID-19 Admitted to Hospital |
Coronavirus disease 19 infection, Deep vein thrombosis, Lung embolism |
ultrasonography alone |
|
|
Foundation for the study of VTE diseases (FUENTE) |
|
Spain |
2020-04-13 |
2025-06-30 |
NCT04380792, SCREENING, SCREENING042020 |
Phase Not Applicable |
Recruiting |
1 |
62 Months |
5000 |
Manuel Monreal, Mayra Hawkins |
2020-05-12 |
| MEND: An open-label, randomized controlled clinical trial to investigate early efficacy of Cymerus mesenchymal stem cells (MSCs) in adults admitted to intensive care with COVID-19 and respiratory distress |
Coronavirus disease 19 infection, Respiratory distress syndrome |
mesenchymoangioblast-derived mesenchymal stem cell therapy (Cymerus, critical limb ischemia/graft versus host disease/asthma/diabetic foot ulcer), Cynata/FUJIFILM alone, standard of care alone |
|
|
Cynata Therapeutics Ltd |
Cerebral Palsy Alliance Research Foundation |
Australia |
|
|
MEND |
Phase Not Applicable |
Not yet recruiting |
1 |
|
24 |
|
2020-05-13 |
| Spread COVID 19 ED: Sorting the wheat form the chaff – COVID-19 in the Emergency department |
Coronavirus disease 19 infection |
SARSCov2-swab test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universitatsklinikum Essen |
|
Germany |
2020-05-07 |
|
20-9310-BO, DRKS00021675, Spread COVID 19 ED |
Phase Not Applicable |
Recruiting |
1 |
|
383 |
Joachim Risse |
2020-05-13 |
| Clinical trial on the treatment of novel coronavirus pneumonia (COVID-19) patients suspected with gut microbiota dysbiosis with washed microbiota transplantation |
Coronavirus disease 19 infection |
Routine treatment alone, Washed microbiota transplantation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Guangzhou 8th People's Hospital |
|
China |
2020-05-08 |
2021-06-08 |
2020KZDZX1132, ChiCTR2000032737 |
Phase 0 Clinical |
Not yet recruiting |
2 |
13 Months |
60 |
Li-Hao Wu, Zhi-Ning Ye |
2020-05-12 |
| Clinical trial evaluating two ventilator settings in Corona virus related severe lung diseases ( known as ARDS) |
Coronavirus disease 19 infection, Respiratory distress syndrome |
Lowest driving pressure guided PEEP alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
All India Institute of Medical Sciences |
|
India |
2020-05-16 |
|
CTRI/2020/05/025071 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
40 |
Dr Ajisha Aravindan |
2020-05-12 |
| TRANSPULMONARY-COVID19: Transpulmonary Driving Pressure in ARDS COVID-19 Patients |
Coronavirus disease 19 infection, Respiratory distress syndrome |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital, Montpellier |
|
France |
2019-04-01 |
2021-12-31 |
NCT04381286, RECHMPL20_0194, TRANSPULMONARY-COVID19 |
Phase Not Applicable |
Recruiting |
1 |
33 Months |
40 |
Ramin SEVERIN, MD, Ramin Séverin, MD |
2020-05-13 |
| MICOV: Low-doses Melphalan Inhalation in Patients With COVID-19 (Coronavirus Disease 2019) Pneumonia |
Bacterial pneumonia, Coronavirus disease 19 infection, Viral pneumonia |
Alkeran alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Federal State Budgetary Institution, Pulmonology Scientific Research Institute |
Medsi Clinic #1, Moscow, Moscow State Medical and Dental University |
Russian Federation |
2020-04-30 |
2020-10-30 |
MICOV, NCT04380376, PSRI05-20 |
Phase 2 Clinical |
Recruiting |
2 |
6 Months |
60 |
Anna Rvacheva, PhD, Evgeny Sinitsyn, Evgeny Sinitsyn, MD, Kiril A Zykov, Prof, Kirill A Zykov, Prof, Kirill Zykov, MD, Kirill Zykov, Prof |
2020-05-13 |
| Had COVID-19 Spread in Nagasaki Prefecture before the first confirmed case? |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Nagasaki University |
|
Japan |
2020-06-01 |
|
UMIN000040278 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
182 |
Katsunori Yanagihara, Norihito Kaku |
2020-05-12 |
| Almitrine and COVID-19 Related Hypoxemia |
Coronavirus disease 19 infection, Hypoxia |
Mostcare (Vygon) alone, Vectarion (Servier Laboratory) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Central Hospital, Nancy, France |
|
France |
2020-03-20 |
2020-04-25 |
COVID-19_CHRU NANCY_2020PI080, NCT04380727 |
Phase Not Applicable |
Completed |
1 |
1 Month |
17 |
Marie Reine LOSSER, MD, PhD |
2020-05-13 |
| COVID-19/Qing Fei Pai Du Tang |
Coronavirus disease 19 infection |
Qing Fei Pai Du Tang alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Tokyo Takanawa Hospital |
|
Japan |
2020-05-09 |
|
UMIN000040341 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
15 |
Tomoka Ebisui, Tsutomu Nakamura |
2020-05-12 |
| Study on risk perception and behavioral change related to COVID-19 |
Coronavirus disease 19 infection |
educational counseling alone, training alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
University of Tokyo |
Ministry of Education, Culture, Sports, Science and Technology of Japan |
Japan |
2020-05-12 |
|
UMIN000040286 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1980 |
Tsuyoshi Okuhara |
2020-05-11 |
| Impacts of COVID-19 on frailty in community-dwelling older adults; a cross-sectional study |
Coronavirus disease 19 infection |
|
|
Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Takasaki University of Health and Welfare |
|
Japan |
2020-05-08 |
|
UMIN000040335 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
346 |
Tomoyuki Shinohara |
2020-05-12 |
| CALAVI US: Acalabrutinib Study With Best Supportive Care Versus Best Supportive Care in Subjects Hospitalized With COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
acalabrutinib alone, best supportive care alone |
Btk tyrosine kinase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
AstraZeneca Pharmaceuticals LP |
Acerta Pharma BV |
US |
2020-05-12 |
2020-09-30 |
CALAVI US, D822FC00003, NCT04380688 |
Phase 2 Clinical |
Not yet recruiting |
0 |
4 Months |
60 |
AstraZeneca Clinical Study Information Center |
2020-05-12 |
| KomCo: Communication in times of the corona virus pandemic (COVID-19) |
Coronavirus disease 19 infection |
|
|
|
Universitätsmedizin Rostock |
|
Germany |
2020-04-02 |
|
A 2020-0068, DRKS00021676, KomCo |
Phase Not Applicable |
Recruiting |
1 |
|
200 |
Christian Junghanß |
2020-05-13 |
| An international clinical trial of oral macrophage activating factor in the prevention of the COVID-19 associated cytokine storm |
Coronavirus disease 19 infection |
macrophage activating factor alone |
|
|
Saisei Pharma Co Ltd |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-05-11 |
| A double-blind clinical study to evaluate the efficacy of the Manremyc food supplement for those health professionals who are most exposed to the risk of contracting COVID-19 |
Coronavirus disease 19 infection |
Manremyc alone |
|
|
Reig Jofre Group |
IDIAP jordi gol, Institut Germans Trias I Pujol (Igtp) |
Spain |
2020-05-31 |
|
|
Phase Not Applicable |
Recruiting |
1 |
|
300 |
Dr. Pere-Joan Cardona |
2020-05-11 |
| Effect of propolis in COVID-19 |
Coronavirus disease 19 infection |
propolis alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Abadan University of Medical Sciences |
|
Iran |
2020-05-21 |
|
IR.ABADANUMS.REC.1399.031, IRCT20200326046868N1 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
88 |
Reza Malihi, Sara Mobarak |
2020-05-12 |
| The effect of herbal syrup on patients with Corona |
Coronavirus disease 19 infection |
herbal thyme syrup intake alone, azithromycin plus lopinavir + ritonavir |
HIV protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Mazandaran University of Medical Sciences |
|
Iran |
2020-04-04 |
|
IR.MAZUMS.REC.1398.1456, IRCT20131129015584N2 |
Phase 3 Clinical |
Recruiting |
1 |
|
152 |
Assie Jokar, Dr Assie Jokar, Dr Majid Saidi |
2020-05-12 |
| The Effect of Convalescent Plasma Therapy on Patients with 19-COVID |
Coronavirus disease 19 infection |
convalescent plasma therapy alone, routine treatment alone |
|
|
Ardabil University of Medical Sciences |
|
Iran |
2020-05-12 |
|
IR.ARUMS.REC.1399.052, IRCT20150808023559N21 |
Phase 1/Phase 2 Clinical |
Recruiting |
1 |
|
60 |
Effat Irani Jam, Shahab Bohlooli, Somaieh Matin |
2020-05-12 |
| Effect of interferon-beta1 (Zifron) on clinical improvement and prognosis of COVID-19 in Tabriz Imam-Reza hospital |
Coronavirus disease 19 infection, Respiratory failure |
Variable regimens including hydroxychloroquine , interferon-beta1, Zifron Zist Darou Danesh , lopinavir + ritonavir |
HIV protease inhibitor |
|
Zist Daru Danesh Company |
|
Iran |
2020-04-29 |
|
IR.TBZMED.REC.1399.019, IRCT20200406046968N3 |
Phase 2 Clinical |
Recruiting |
1 |
|
60 |
Hooshmand Ilka, Mikaeili Haleh |
2020-05-12 |
| RAVEN: Ruxolitinib therapy to Avoid Ventilation and improve outcome for deteriorating COVID-19 patients |
Coronavirus disease 19 infection |
ruxolitinib (oral, myeloproliferative disorders), Incyte/Novartis alone |
Jak1 tyrosine kinase inhibitor, Jak2 tyrosine kinase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Guy's & St Thomas' Hospital NHS Trust |
Novartis Pharmaceuticals UK Ltd |
UK |
2020-05-06 |
|
2020-001777-71, RAVEN, RAVEN |
Phase 4 Clinical |
No longer recruiting |
1 |
|
59 |
Donal McLornan |
2020-05-12 |
| A phase II trial of PPP-003 in covid-19 infected patients |
Coronavirus disease 19 infection |
PPP-003 (intravenous), Tetra Bio-Pharma alone |
Cannabinoid CB2 receptor agonist |
|
Tetra Bio-Pharma Inc |
Onegevity Health LLC |
|
|
|
|
Phase 2 Clinical |
Planned |
0 |
|
100 |
|
2020-05-12 |
| A study of subclinical infection of COVID-19 in Kanagawa prefecture |
Coronavirus disease 19 infection |
Test for COVID-19 alone |
|
|
Kanagawa Physicians Association |
|
Japan |
2020-05-20 |
|
UMIN000040333 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1000 |
Ikuro Matsuba |
2020-05-12 |
| A clinical trial of DARPin for the potential treatment of COVID-19 caused by SARS-CoV-2 |
Coronavirus disease 19 infection |
DARPin (COVID-19), Molecular Partners alone |
Angiotensin converting enzyme 2 inhibitor |
|
Molecular Partners AG |
|
|
2020-12-31 |
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-05-11 |
| A phase IIb/III multinational clinical trial of NP-120 (ifenprodil (injectable/intravenous, COVID-19/acute lung injury), Nash Pharmaceuticals) for the treatment in COVID-19 diagnosed patients |
Coronavirus disease 19 infection |
ifenprodil (injectable/intravenous, COVID-19/acute lung injury), Nash Pharmaceuticals alone, standard of care (SOC) alone |
NMDA receptor epsilon 2 subunit inhibitor |
|
Algernon Pharmaceuticals |
|
Canada, South Korea |
|
|
|
Phase 2/Phase 3 Clinical |
Not yet recruiting |
2 |
|
100 |
|
2020-05-11 |
| A phase IIb/III multinational clinical trial of NP-120 (ifenprodil (long-acting, oral, COVID-19/acute lung injury), Nash Pharmaceuticals) for the treatment in COVID-19 diagnosed patients |
Coronavirus disease 19 infection |
ifenprodil (long-acting, oral, COVID-19/acute lung injury), Nash Pharmaceuticals alone, standard of care (SOC) alone |
NMDA receptor epsilon 2 subunit inhibitor |
|
Algernon Pharmaceuticals |
|
Canada, South Korea |
|
|
|
Phase 2/Phase 3 Clinical |
Not yet recruiting |
2 |
|
100 |
|
2020-05-11 |
| Psychological effects of social isolation in the pandemic coronavirus |
Coronavirus disease 19 infection |
social isolation alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universidade Federal do Para |
|
Canada, Colombia, Brazil, US, Chile, France, UK, Spain, Portugal |
2020-04-07 |
2020-05-30 |
3,960,596, 30365720.8.0000.0008, RBR-9pgwfc, U1111-1250-1962 |
Phase Not Applicable |
Recruiting |
8 |
1 Month |
2300 |
Janari Silva Pedroso |
2020-05-13 |
| Investigating a vaccine against COVID-19 |
Coronavirus disease 19 infection |
ChAdOx1 nCoV-19 alone, Nimenrix alone |
COVID19 Spike glycoprotein modulator |
Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Oxford |
Coalition for Epidemic Preparedness Innovations, United Kingdom Research & Innovation |
UK |
2020-03-02 |
2021-06-30 |
2020-001228-32, COV002, CPMS 45551, IRAS 281904, ISRCTN90906759 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
7 |
15 Months |
5260 |
Mrs Plested |
2020-05-14 |
| An Expanded Access program of use of Convalescent Plasma for Severe COVID-19 |
Coronavirus disease 19 infection |
convalescent plasma alone |
|
|
OneBlood, University of Miami Health System |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
|
Shweta Anjan |
2020-05-08 |
| A phase I clinical trial of live attenuated SARS-CoV-2 virus vaccine for the prevention of SARS-CoV-2 COVID-19 infection |
Coronavirus disease 19 infection |
SARS-CoV-2 vaccine (recombinant measles virus vector, COVID-19), German Center for Infection Research alone |
COVID19 Spike glycoprotein modulator, COVID19 nucleoprotein modulator |
|
German Center for Infection Research (DZIF) |
|
|
|
|
|
Phase 1 Clinical |
Planned |
0 |
|
|
|
2020-05-11 |
| Study for the application of novel coronavirus pneumonia (COVID-19) intestinal tract toxicity in diagnosis and its prognostic effect |
Coronavirus disease 19 infection, Viral pneumonia |
probiotic plus rifaximin |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Union Hospital Tongji Medical School Huazhong University Of Science & Technology |
|
China |
2020-05-04 |
2021-12-31 |
ChiCTR2000032686 |
Phase Not Applicable |
Not yet recruiting |
1 |
19 Months |
390 |
Xiaohua Hou, Yu Jin |
2020-05-11 |
| Follow-up study of pregnancy outcomes of novel coronavirus pneumonia (COVID-19) complicated in the first and second trimester |
Coronavirus disease 19 infection |
|
|
Female, Young Adults (18-44 yrs) |
Union Hospital Tongji Medical School Huazhong University Of Science & Technology |
|
China |
2020-04-01 |
2020-12-31 |
ChiCTR2000032666 |
Phase Not Applicable |
Recruiting |
1 |
9 Months |
6 |
Zhao Yin |
2020-05-11 |
| A phase I clinical trial to assess the tolerability and immune response of recombinant MVA vector vaccine fo the prevention of SARS-CoV-2 COVID-19 infection |
Coronavirus disease 19 infection |
recombinant MVA vector vaccine (COVID-19), German Center for Infection Research alone |
COVID19 Spike glycoprotein modulator |
|
German Center for Infection Research (DZIF) |
|
|
|
|
|
Phase 1 Clinical |
Planned |
0 |
|
|
|
2020-05-08 |
| A clinical trial of SARS-CoV-2 therapy for the prevention/treatment of COVID-19 infection |
Coronavirus disease 19 infection |
SARS-CoV-2 therapy (COVID-19), Shionogi/Hokkaido University Research Center alone |
|
|
Hokkaido University, Shionogi & Co Ltd |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-05-08 |
| Study for efficacy and safety of Jie-Xing-Jun-Zi granules in the Treatment of convalescent patients of novel coronavious pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Jiexingjunzi granules alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
The Third affiliated Hospital of Beijing Traditional Chinese Medicine University |
|
China |
2020-05-01 |
2020-12-31 |
ChiCTR2000032313, ChiMCTR2000003243 |
Phase 0 Clinical |
Not yet recruiting |
3 |
8 Months |
60 |
Hongsheng Cui, Xinxin Qin |
2020-05-11 |
| A medical records based study for optimization and evaluation of the comprehensive diagnosis and treatment of novel coronavirus pneumonia (COVID-19) and the assessment of risk factors for severe pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
The First Affiliated Hospital of Nanchang University |
|
China |
2020-01-31 |
2020-07-31 |
ChiCTR2000030095 |
Phase 0 Clinical |
Recruiting |
1 |
6 Months |
94 |
Anjun Chen, Wei Zhang |
2020-05-11 |
| Study for Screening of Chinese Patent Drugs in the Rehabilitation Treatment of Novel Coronavirus Pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Pien Tze Huang capsule plus thymosin enteric capsule |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Hubei province hospital of Traditional Chinese Medicine |
Ministry of Science and Technology of the People´s Republic of China |
China |
2020-04-01 |
2021-03-31 |
ChiCTR2000032635, ChiMCTR2000003279 |
Phase 0 Clinical |
Not yet recruiting |
1 |
12 Months |
60 |
He Shaobin, Zhuo Yana |
2020-05-11 |
| Moxibustion Plus Cupping in Convalescent Patients With COVID-19 |
Coronavirus disease 19 infection |
Moxibustion plus Cupping alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Guang'Anmen Hospital China Academy of Chinese Medical Sciences |
Ezhou Hospital of traditional Chinese Medicine in Hubei Province, Huangshi Hospital of Traditional Chinese Medicine, Hubei Hospital of Integrated Traditional Chinese and Western Medicine Zhongshan Branch, Hubei province hospital of Traditional Chinese Medicine, Shenzhen Baoan Hospital of Tradition Chinese Medicine, The Affiliated Hospital of JiangXi University of TCM, China, The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine, Wuhan Hospital of Traditional Chinese Medicine, Wuhan third Hospital |
China |
2020-05-31 |
2021-12-31 |
2020YFC0845000, NCT04374084 |
Phase Not Applicable |
Not yet recruiting |
1 |
19 Months |
60 |
Jiani Wu, Xiaopin Wang, Zhongyu Zhou |
2020-05-12 |
| SurgiCovid: Surgical Activity During the Covid-19 Pandemic: Results for 112 Patients in a French Tertiary Care Center |
Coronavirus disease 19 infection |
Computed tomography chest alone, Reverse transcription polymerase chain reaction test alone, Screening test for covid alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospices Civils De Lyon |
|
France |
2020-03-19 |
2020-04-25 |
CRC_GHN_2020_001, NCT04379232, SurgiCovid |
Phase Not Applicable |
Completed |
1 |
1 Month |
112 |
|
2020-05-11 |
| FUTURE-T: Clinical Effect of Dialyzable Leukocyte Extract in Suspected or Confirmed Cases of COVID-19 |
Coronavirus disease 19 infection |
Dialyzable Leukocyte Extract alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Instituto Politecnico Nacional |
|
Mexico |
2020-05-31 |
2020-12-31 |
FUTURE-T, IC-20-001, NCT04379479, SH-001-2020 |
Phase 2 Clinical |
Not yet recruiting |
1 |
7 Months |
562 |
Maria C Jimenez-Martínez, MD PhD, Maricarmen Sánchez-Leon, MD, Maricarmen Sánchez-León, MD, Melissa I Espinosa-Navarro, MD, Sonia Mayra Pérez-Tapia, PhD, Toni A Homberg von Thaden, MD, Toni A Homberg, MD |
2020-05-11 |
| Social Media and Covid19 Pandemic |
Coronavirus disease 19 infection |
survey alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Acibadem University |
|
Turkey |
2020-05-01 |
2020-05-08 |
ACIBADEMU SOCIAL MEDIA, NCT04378738 |
Phase Not Applicable |
Recruiting |
2 |
|
212 |
|
2020-05-11 |
| A clinical trial to investigate and define the molecular mechanisms of SARS-CoV-2 infection and COVID-19 and identify targets for medicines and vaccines |
Coronavirus disease 19 infection |
|
|
|
Institute For Systems Biology, Merck & Co Inc |
10X Technologies Inc, Adaptive Biotechnologies Corp, Andy Hill CARE Fund, Biomedical Advanced Research and Development Authority (BARDA), Bloodworks Northwest, Isoplexis Corp, M.J. Murdock Charitable Trust, Metabolon Inc, NanoString Technologies Inc, Parker Institute for Cancer Immunotherapy, Scisco Genetics Inc, Stanford University, Swedish Hospital, Wilkes University |
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
200 |
Dr. Jason D. Goldman |
2020-05-08 |
| Efficacy of Liu-zi-jue in patients with 2019 novel Coronavirus pneumonia (COVID-19): a randomized, controlled trial |
Coronavirus disease 19 infection, Viral pneumonia |
Liu-zi-jue alone, conventional treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Shanghai University of Traditional Chinese Medicine |
|
China |
2020-02-19 |
2020-07-31 |
ChiCTR2000032367, ChiMCTR2000003246 |
Phase Not Applicable |
Recruiting |
2 |
5 Months |
186 |
Min Fang, Shuaigpan Zhang |
2020-05-11 |
| Lingnan Fire-Needle Therapy Improves the Quality of Life in General Population Under the Pandemic of Novel Coronavirus Pneumonia (COVID-19): A Prospective, Randomized Controlled Trial |
Coronavirus disease 19 infection, Viral pneumonia |
lingnan fire needle therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
The first affiliated hospital of Guangzhou university of Traditional Chinese medicine |
|
China |
2020-04-27 |
2020-12-31 |
ChiCTR2000032346, ChiMCTR2000003245 |
Phase 0 Clinical |
Recruiting |
1 |
8 Months |
120 |
Guohua Lin, Jingchun Zeng |
2020-05-11 |
| Neurologic Manifestations of COVID 19 in Children |
Coronavirus disease 19 infection |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) |
University of Pittsburgh |
Johns Hopkins University, University of Utah |
US |
2020-04-29 |
2022-12-31 |
NCT04379089, STUDY20040154 |
Phase Not Applicable |
Recruiting |
0 |
32 Months |
500 |
David Maloney, BS, Ericka L Fink, Ericka L Fink, MD |
2020-05-11 |
| COPING: COVID Pandemic Short Interval National Survey Gauging Psychological Distress |
Acute stress disorder, Coronavirus disease 19 infection |
|
|
|
Nova Scotia Health Authority |
|
Canada |
2020-05-31 |
2022-05-31 |
COPING, NCT04379063, Temporary REB#25470 |
Phase Not Applicable |
Not yet recruiting |
1 |
24 Months |
10000 |
Jonathan Bailey, MD MSc FRCPC |
2020-05-12 |
| CovRep: Effector and Regulatory T-Cell Receptor Repertoire Analysis in Patients Affected by COVID-19 |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Assistance Publique Hopitaux de Paris |
|
France |
2020-05-31 |
2020-11-30 |
2020-A01245-34, APHP200544, CovRep, NCT04379466 |
Phase Not Applicable |
Not yet recruiting |
1 |
6 Months |
60 |
David KLATZMANN, MD, PhD, Roberta LORENZON, MD |
2020-05-12 |
| Rintatolimod and IFN Alpha-2b for the Treatment of Mild or Moderate COVID-19 Infection in Cancer Patients |
Coronavirus disease 19 infection |
interferon alfa-2b plus rintatolimod |
2,5-Oligoadenylate synthetase stimulator, Interferon alpha ligand modulator, Interferon type I receptor agonist, Ribonuclease stimulator, TLR-3 agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Roswell Park Comprehensive Cancer Center |
National Cancer Institute |
US |
2020-05-30 |
2021-04-30 |
I 659920, I 659920, NCI-2020-02317, NCT04379518, P30CA016056 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
0 |
11 Months |
80 |
Brahm H Segal, Brahm H. Segal |
2020-05-11 |
| A phase II study to assess the effect of DW-2008 in the treatment of COVID-19 patients |
Coronavirus disease 19 infection |
DW-2008 alone |
|
|
Dong Wha Pharmaceutical Co Ltd |
|
|
2020-06-30 |
|
|
Phase 2 Clinical |
Planned |
0 |
|
|
|
2020-05-08 |
| Impact on Anxiety and Motivation of COVID-19 and Predictors of Individual Responses |
Anxiety disorder, Cognitive disorder, Coronavirus disease 19 infection, Psychiatric disorder |
Computer task questionnaires alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The National Institute of Mental Health |
National Institutes of Health Clinical Center |
US |
2020-05-18 |
2021-02-28 |
20-M-N112, 999920112, NCT04377100 |
Phase Not Applicable |
Not yet recruiting |
0 |
9 Months |
500 |
Monique Ernst, M.D., Morgan Andrews, Ph.D. |
2020-05-14 |
| IMPACC: Immunophenotyping Assessment in a COVID-19 Cohort |
Coronavirus disease 19 infection |
genome-wide association analysis alone, immunophenotyping alone, serial biological sampling alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Institute of Allergy and Infectious Diseases |
Benaroya Research Center at Virginia Mason, Boston Children's Hospital |
US |
2020-05-01 |
2021-12-31 |
DAIT-COVID-19-002, IMPACC, NCT04378777 |
Phase Not Applicable |
Recruiting |
0 |
20 Months |
2000 |
Albert C. Shaw, MD, Alejandra Jauregui, Allison Nelson, Carolyn S. Calfee, MD, MAS, Charles B. Cairns, MD, Elaine Reed, PhD, Grace McComsey, MD, Hannah Jin, Hena Din, MPH, Jennifer Sustin, Joanna M. Schaenman, MD, PhD, Kari C. Nadeau, MD, PhD, Karina Oganezova, Komal Srivastava, Laurel Bristow, Lindsey R. Baden, MD, Mariana Bernui, Nadine Rouphael, M.D., Nadine Rouphael, MD, Sarah Siegel, Viviana A. Simon, MD, PhD, William B. Messer, MD, PhD |
2020-05-12 |
| Serological Testing for COVID-19 (SARS-CoV-2) in ESKD |
Coronavirus disease 19 infection, End stage renal disease |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universitaire Ziekenhuizen Leuven |
|
Belgium |
2020-04-23 |
2022-05-01 |
NCT04378686, S64000 |
Phase Not Applicable |
Recruiting |
2 |
24 Months |
500 |
Annelien Van Der Veen, MD, Bjorn Meijers, MD, PhD, Björn Meijers, Helga Wielandt, Koen Stas, MD |
2020-05-13 |
| LDCTiP: LDCT in COVID-19 Pneumonia: a Prospective Moscow Study |
Coronavirus disease 19 infection, Viral pneumonia |
Low-dose Chest CT alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Federal State Institution "Medical Radiological Research Center" |
|
Russian Federation |
2020-05-31 |
2020-07-31 |
2020-1, LDCTiP, NCT04379531 |
Phase Not Applicable |
Not yet recruiting |
1 |
2 Months |
230 |
Anton Vladzymyrskyy, Ivan Blokhin, Valeria Chernina, Victor Gombolevskiy, PhD |
2020-05-12 |
| VOC-COVID: Analysis of Volatile Organic Compounds by Electronic Noses in Hospitalized Patients for an Infection by SARS-CoV-2 (COVID-19) |
Coronavirus disease 19 infection, Respiratory disease |
electronic nose alone, volatile organic compounds analysis alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hopital Foch |
|
France |
2020-04-14 |
2020-11-16 |
2020-0060, NCT04379154, VOC-COVID |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
60 |
Elisabeth Hulier-Ammar, Hélène Salvator |
2020-05-12 |
| A randomized clinical trial for the efficacy and safety of aliskiren and nifedipine in novel coronavirus pneumonia (COVID-19) patients with hypertension |
Coronavirus disease 19 infection, Hypertension, Viral pneumonia |
aliskiren alone, nifedipine alone, standard care alone |
Calcium channel inhibitor L-type, Renin inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
West China Hospital |
|
China |
2020-03-01 |
2020-12-31 |
ChiCTR2000032314 |
Phase 0 Clinical |
Recruiting |
5 |
10 Months |
242 |
Fengming Luo, Min Zhu |
2020-05-11 |
| Evaluation of Clinical Parameters on Admission and Medications in Covid-19 Pneumonia (Corona Virus Disease 2019) (Covid-19) |
Coronavirus disease 19 infection, Viral pneumonia |
ACE inhibitor therapy alone, calcium channel blocker therapy alone, computed tomography alone, polymerase chain reaction test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Nisantasi University |
|
Turkey |
2020-05-01 |
2020-05-08 |
20200504441, NCT04379310 |
Phase Not Applicable |
Recruiting |
1 |
|
60 |
Hasan Haciosman, Hasan Haciosman, M.D., Murat Civan, Murat Civan, M.D. |
2020-05-11 |
| Vagus Nerve Stimulation ARDS Prevention Trial for COVID-19 Hospitalized Patients |
Coronavirus disease 19 infection, Lung disease, Respiratory distress syndrome, Viral pneumonia |
transcutaneous auricular vagus nerve stimulation alone, transcutaneous auricular vagus nerve stimulator (Nemechek Technologies) alone |
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Nemechek Technologies |
|
|
2020-07-31 |
2021-01-31 |
NCM-001, NCT04379037 |
Phase Not Applicable |
Not yet recruiting |
0 |
6 Months |
50 |
Jean R Nemechek, JD, Patrick M Nemechek, D.O. |
2020-05-11 |
| Viral Infections in Healthy and Immunocompromised Hosts |
Coronavirus disease 19 infection, Viral infection |
|
|
Healthy volunteers accepted, Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs) |
National Institute of Allergy and Infectious Diseases |
National Institutes of Health Clinical Center |
US |
2011-03-05 |
|
11-I-0109, 110109, NCT01306084 |
Phase Not Applicable |
Recruiting |
0 |
|
164 |
Jeffrey I Cohen, M.D. |
2020-05-12 |
| Peer Champion Support for Hospital Staff During and After the COVID-19 Pandemic |
Coronavirus disease 19 infection |
Enriched Survey Feedback alone, Peer Resilience Champion alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Mount Sinai Hospital |
Canadian Institutes of Health Research |
Canada |
2020-06-30 |
2022-02-28 |
20-0084-E, NCT04373382 |
Phase Not Applicable |
Not yet recruiting |
1 |
20 Months |
1000 |
Robert G Maunder |
2020-05-11 |
| Robot Assisted Percutaneous Cardiovascular Intervention as a Strategy to Reduce or Risk of Intra-Procedure Contamination by COVID-19 and Other Respiratory Viruses |
Cardiovascular disease, Coronavirus disease 19 infection, Ischemic heart disease |
Robot Assisted Percutaneous Cardiovascular Intervention alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sociedade Beneficente Israelita Brasileira Hospital Albert Einsten |
|
Brazil |
2020-04-27 |
2020-04-27 |
4094-20, NCT04379453 |
Phase Not Applicable |
Recruiting |
1 |
|
10 |
Marcelo Franken, MD, Pedro A Lemos, MD, Pedro Lemos, MD |
2020-05-11 |
| Risks of COVID-19 in the Pregnant Population |
Coronavirus disease 19 infection |
Biospecimen collection alone |
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Mayo Clinic Foundation |
|
US |
2020-05-05 |
2021-07-31 |
20-003251, NCT04379284 |
Phase Not Applicable |
Not yet recruiting |
0 |
14 Months |
100 |
Ann L VanOosten, Maureen A Lemens, BSN, Regan N Theiler, MD, PhD |
2020-05-12 |
| Simulation of Risk of Adverse Drug Events Associated With the Initiation of Drugs Repurposed for the Treatment of COVID-19 in Adults With Polypharmacy Using Data From Large Medicare and Commercially Insured Populations |
Coronavirus disease 19 infection |
drug therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tabula Rasa HealthCare Inc |
Cambia Health Solutions Inc |
US |
2020-05-05 |
2021-04-30 |
COVID19-TRHC-2020-002, NCT04378881 |
Phase Not Applicable |
Not yet recruiting |
0 |
11 Months |
100 |
Pamela Dow, MS, Veronique Michaud, Veronique Michaud, PhD |
2020-05-11 |
| UC-COVID: Understanding Community Considerations, Opinions, Values, Impacts, and Decisions for COVID-19 |
Coronavirus disease 19 infection |
Brief educational video alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of California Los Angeles |
|
US |
2020-05-08 |
2020-12-31 |
NCT04373135, UC-COVID, UCLA-20-000683 |
Phase Not Applicable |
Recruiting |
0 |
7 Months |
1000 |
Lauren E Wisk, PhD, Russell G Buhr, MD, PhD |
2020-05-13 |
| ILIAD-7-UK: InterLeukin-7 (CYT107) to Improve Clinical Outcomes in Lymphopenic pAtients With COVID-19 Infection UK Cohort |
Coronavirus disease 19 infection, Lymphocytopenia |
CYT-107 alone |
IL-7 receptor agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Revimmune Inc |
Amarex Clinical Research |
|
2020-05-11 |
2020-12-30 |
CLI107 COVID UK, ILIAD-7-UK, NCT04379076 |
Phase 2 Clinical |
Not yet recruiting |
0 |
7 Months |
48 |
Frederique Berbille, MHSc, Manu Shankar-Hari, MD PhD, Michel Morre, DVM MSc |
2020-05-12 |
| Analysis of Mortality of Critically Ill Patients With COVID-19 |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Universitario de Getafe |
Fundación Para La Investigación Biomédica Del Hospital De La Princesa, Hospital General Universitario Gregorio Marañon, Hospital Infanta Cristinam, Hospital Puerta de Hierro Majadahonda, Hospital Universitario Madrid Sanchinarro, Hospital Universitario Ramon y Cajal, Hospital Universitario Severo Ochoa, Hospital Universitario de Mostoles, Hospital de Henares, Hospital de Sant Pau, La Paz University Hospital (Madrid), University Hospital of Torrejon, University of Gregorio Maranon |
Spain |
2020-05-11 |
2020-05-30 |
COVID-UCI_SPAIN, NCT04379258 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
650 |
Laura Ojalvo, Oscar Peñuelas, P.h.D |
2020-05-14 |
| Hydrogen/Oxygen Mixed Gas Inhalation for Coronavirus Disease 2019 (COVID-19) |
Coronavirus disease 19 infection, Dyspnea |
Standard of care alone, hydrogen + oxygen alone, hydrogen oxygen generator (AMS-H-03, Shanghai Asclepius Meditec Co., Ltd., China) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Guangzhou Institute Of Respiratory Disease |
|
China |
2020-01-21 |
2020-03-23 |
JT202005LZ, NCT04378712 |
Phase 2 Clinical |
Completed |
2 |
2 Months |
90 |
Wei-jie Guan, PhD |
2020-05-11 |
| Unplanned Shifting to Online Distance Learning: Nursing Students' Perception and Achievement (COVID-19) |
Coronavirus disease 19 infection |
implimenting Online Distance Learning alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kasr El Aini Hospital |
|
Egypt |
2020-02-01 |
2020-06-30 |
FON170133, NCT04372693 |
Phase Not Applicable |
Recruiting |
1 |
5 Months |
180 |
Sameh Elhabashy |
2020-05-12 |
| Platelet Count, Platelet, Mean Platelet Volume and Platelet Distribution Width in COVID-19 |
Coronavirus disease 19 infection |
|
|
|
Konya Training And Research Hospital |
|
|
2020-05-04 |
2020-05-13 |
COVID-19, NCT04378829 |
Phase Not Applicable |
Not yet recruiting |
0 |
|
40 |
Yasin TİRE |
2020-05-11 |
| Nudges to Limit COVID-19 |
Coronavirus disease 19 infection |
Behavioral Nudges (BN) alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Medical College of Wisconsin |
|
US |
2020-05-11 |
2020-10-10 |
NCT04379375 |
Phase Not Applicable |
Not yet recruiting |
0 |
5 Months |
300 |
Nicholas D Young, PhD |
2020-05-11 |
| COVID-BMR: COVID-19 and ICU-acquired MDR Bacteria |
Bacterial infection, Coronavirus disease 19 infection, Multidrug resistant infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Regional Universitaire de Lille |
|
France |
2020-05-31 |
2021-05-31 |
2020-A01157-32, 2020_37, COVID-BMR, NCT04378842 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
690 |
Saad Nseir, MD,PhD |
2020-05-11 |
| Innovative Tool to Limit Spread of SARS-CoV-2 in Residential Aged Care Facilities |
Coronavirus disease 19 infection |
Gamification function alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Queensland |
|
|
2020-05-06 |
2020-06-04 |
CARE COLLECTIVE STUDY, NCT04377165 |
Phase Not Applicable |
Not yet recruiting |
0 |
|
9000 |
Anna Donaldson, Caitlin Falconer, David L Paterson, PhD |
2020-05-11 |
| CORONA: a Study Using DeltaRex-G Gene Therapy for Symptomatic COVID-19 |
Coronavirus disease 19 infection |
Rexin-G alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Aveni Foundation |
|
US |
2020-06-12 |
2021-03-12 |
AF20-203, NCT04378244 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
0 |
9 Months |
18 |
Erlinda M Gordon, MD, Sant P Chawla, MD, Victoria Chua-Alcala, MD |
2020-05-11 |
| CON-VINCE: Covid-19 National Survey for Assessing Viral Spread by Nonaffected Carriers |
Coronavirus disease 19 infection |
Covid-19 national survey alone, RT-PCR test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Luxembourg Institute of Health |
BioneXt Lab, Centre Hospitalier de Luxembourg, Ketterthill, Laboratoire National de santé, Laboratoires Réunis, Luxembourg Centre for Systems Biomedicine, Luxembourg National Research Funds, TNS-Ilres, Universite of Luxembourg |
Luxembourg |
2020-04-10 |
2021-12-31 |
831X6CE0D, CNER 202004/01, CON-VINCE, FNR/CON-VINCE, NCT04379297 |
Phase Not Applicable |
No longer recruiting |
1 |
20 Months |
1800 |
Rejko Krüger, Dr |
2020-05-11 |
| BCG Vaccination for Healthcare Workers in COVID-19 Pandemic |
Coronavirus disease 19 infection |
BCG vaccine Danish strain 1331 (Statens Serum Institute) alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Applied Sciences Inc |
|
South Africa |
2020-05-04 |
2021-04-28 |
NCT04379336, TASK-008 BCG-CORONA |
Phase 3 Clinical |
Recruiting |
1 |
11 Months |
500 |
Caryn M Upton, MBChB, Caryn Upton, MD, Christelle Van Niekerk |
2020-05-11 |
| FRESH: Fluid Response Evaluation in Sepsis Hypotension and Shock study |
Coronavirus disease 19 infection, Hypotension, Septic shock |
Baxter’s Starling Fluid Management Monitoring System alone, Passive Leg Raises alone, vasopressor therapy alone |
|
|
Baxter International Inc |
|
US, UK |
|
|
FRESH |
Phase Not Applicable |
Status not specified |
1 |
|
|
Ivor Douglas |
2020-05-08 |
| A Study of Hydroxycholoroquine Compared to Placebo as Treatment for People With COVID-19 |
Coronavirus disease 19 infection |
hydroxychloroquine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Memorial Sloan-Kettering Cancer Center |
|
US |
2020-05-05 |
2021-05-31 |
20-187, NCT04379492 |
Phase 2 Clinical |
Recruiting |
0 |
12 Months |
120 |
Genovefa Papanicolaou, MD, Susan Seo, MD |
2020-05-13 |
| A Study of Trans Crocetin in Patients With Acute Respiratory Distress Syndrome Due to COVID-19 Disease (LEAF-4L7520/4L6715) (LEAF-4L6715) |
Coronavirus disease 19 infection, Respiratory distress syndrome |
LEAF-4L6715 alone, LEAF-4L7520 alone, artificial respiratory support therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Institut de Cancerologie Strasbourg Europe |
LEAF4Life LLC |
France |
2020-04-14 |
2020-10-31 |
2020-001393-30, 2020-003, 2020-A00900-39, NCT04378920 |
Phase 1/Phase 2 Clinical |
Recruiting |
2 |
6 Months |
180 |
Manon VOEGELIN, Manon VOEGELIN, PhD, Olivier COLLANGE, PhD MD, Paul Michel MERTES, PhD MD, Valerie SARTORI, Vitaliy CHABAN, MD |
2020-05-11 |
| Efficacy and safety of high-dose vitamin C combined with traditional Chinese medicine in the treatment of moderate and severe novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Chinese medicine alone, Buzhong Yiqi Decoction plus vitamin C |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Xi'an International Medical Center Hospital |
Shaanxi Hospital of Traditional Chinese Medicine |
China |
2020-02-06 |
2021-01-31 |
ChiCTR2000032717, ChiMCTR2000003284 |
Phase Not Applicable |
No longer recruiting |
2 |
11 Months |
60 |
Xijing He |
2020-05-12 |
| High dose intravenous vitamin C might be used as an important rescue therapy for aggravation of severe and critical novel coronavirus pneumonia (COVID-19) patients |
Coronavirus disease 19 infection, Viral pneumonia |
vitamin C alone |
|
|
Rui Jin Hospital |
Science and Technology Commission of Shanghai Municipality |
China |
2020-02-05 |
2020-04-30 |
ChiCTR2000032716 |
Phase Not Applicable |
No longer recruiting |
1 |
2 Months |
12 |
Bing Zhao, Enqiang Mao |
2020-05-11 |
| Assessing Pediatric Food Insecurity During the COVID-19 Pandemic in Austin |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Texas System |
|
US |
2020-04-10 |
2021-07-30 |
2020-004-0019, NCT04378595 |
Phase Not Applicable |
Recruiting |
0 |
15 Months |
1000 |
Ana Avalos, MD, Keli Hawthorne, Keli Hawthorne, MS, Megan Gray, MD, Steve Abrams, MD, Steven Abrams |
2020-05-11 |
| Prevalence of Long-term Respiratory Complications of Severe SARS-CoV-2 Pneumonia |
Coronavirus disease 19 infection, Respiratory disorder, Viral pneumonia |
blood sample and data record alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire de Reims |
|
France |
2020-05-15 |
2021-10-15 |
NCT04376840, PO20066 |
Phase Not Applicable |
Not yet recruiting |
1 |
17 Months |
240 |
Jeanne-Marie PEROTIN-COLLARD |
2020-05-11 |
| COM-COVID: Assessment of the Psycho-social Impact of COVID-19 Outbreak |
Coronavirus disease 19 infection |
COM-COVID anonimous survey alone |
|
Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fundació Institut Germans Trias i Pujol |
Anaxomics Biotech, Fundació Lluita contra la SIDA |
Spain |
2020-03-31 |
2020-12-31 |
COM-COVID, COM-COVID, NCT04378452 |
Phase Not Applicable |
Recruiting |
3 |
9 Months |
65000 |
Carol Armengol, PhD, Cris Vilaplana, MD, PhD, José A Muñoz-Moreno, PhD, Judith Farrés, PhD, Lilibeth Arias, PhD, Maria Rosa Sarrias, PhD, Pau Benito, Pere-Joan Cardona, MD, PhD |
2020-05-11 |
| A Study to Evaluate the Efficacy, Safety and Tolerability of IMU-838 as Addition to Investigator's Choice of Standard of Care Therapy, in Patients With Coronavirus Disease 19 (COVID-19) |
Coronavirus disease 19 infection |
standard-of-care antiviral therapy alone, vidofludimus alone, Variable regimens including chloroquine , hydroxychloroquine , vidofludimus |
Dihydroorotate dehydrogenase inhibitor, IL-17 antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Immunic AG, Immunic Inc |
FGK Clinical Research GmbH |
Europe, US |
2020-05-31 |
2020-10-31 |
NCT04379271, P2-IMU-838-COV |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
0 |
5 Months |
230 |
Andreas Muehler, Dr., Neera Ahuja, Prof. |
2020-05-12 |
| Safety and Efficacy of Therapeutic Anticoagulation on Clinical Outcomes in Hospitalized Patients With COVID-19 |
Blood clotting disorder, Coronavirus disease 19 infection, Viral pneumonia |
enoxaparin sodium plus unfractionated heparin |
Low molecular weight heparin |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Massachusetts General Hospital |
Beth Israel Deaconess Medical Center, Dartmouth-Hitchcock Medical Center |
US |
2020-05-15 |
2022-01-01 |
2020P001136, NCT04377997 |
Phase 2 Clinical |
Not yet recruiting |
0 |
19 Months |
300 |
Jaclyn Pagliaro, MPH, Mazen Albaghdadi, MD |
2020-05-11 |
| EpiCoV-Brazil: Characteristics and Outcomes of Patients With COVID-19 Admitted to the ICU |
Coronavirus disease 19 infection |
|
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo |
|
Brazil |
2020-05-10 |
2020-12-31 |
31382620.0.0000.0068, EpiCoV-Brazil, NCT04378582 |
Phase Not Applicable |
Not yet recruiting |
1 |
7 Months |
300 |
Juliana C Ferreira, MD |
2020-05-11 |
| GEROCOVIDobs: Geriatric Population COVID-19 Observational Study |
Coronavirus disease 19 infection |
|
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universita Campus Bio MediCo Di Roma |
BLUECOMPANION FRANCE, Italian Society of Gerontology and Geriatrics |
Italy |
2020-04-25 |
2020-11-30 |
GC01-OBS, GEROCOVIDobs, NCT04379440 |
Phase Not Applicable |
Recruiting |
7 |
7 Months |
1500 |
Raffaele Antonelli Incalzi, M.D., Susanna Del Signore, M.D. |
2020-05-11 |
| COVIDHIVPrEP: COVID-19 Infection in Patients Infected With HIV and/or on PrEP |
Coronavirus disease 19 infection, HIV infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospices Civils De Lyon |
|
France |
2020-04-30 |
2020-05-04 |
COVIDHIVPrEP, CRC_GHN_2020_002, NCT04379245 |
Phase Not Applicable |
Completed |
1 |
|
4200 |
|
2020-05-11 |
| CLUSCO: Prognostic Value of Point of Care Cardiac and Lung Ultrasound in COVID-19 |
Coronavirus disease 19 infection, Respiratory failure |
cardiopulmonary ultrasound alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Pennsylvania |
|
US |
2020-04-23 |
2020-12-31 |
843008, CLUSCO, NCT04379544 |
Phase Not Applicable |
Recruiting |
0 |
8 Months |
105 |
Brian Luu, MD, Cameron Baston, MD, Christy Moore, Claire Centeno, EMT, Dave Poliner, MD, Deepti Kilaru, MD, Emily Gordon, MD, Felipe Teran, MD, Hari Shankar, MD, Jeffery Kramer, MD, Jennifer Morganroth, MD, Jesse Kiefer, MD, Meghan Lane-fall, MD, Nahreen Ahmed, MD, Nathaniel Reisinger, MD, Nova Panebianco, MD, Oscar Mitchell, MD, Scott Falk, MD, Scott Tilton, Steven Pugliese, MD |
2020-05-12 |
| Effects of tests for covid-19 on the preservation of the healthcare workforce during pandemic in Brazil |
Coronavirus disease 19 infection |
RT-PCR testing alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
University Hospital of Brasilia |
|
Brazil |
2020-04-30 |
|
3,959,938, 30540720.2.0000.0008, RBR-6w5tbk, U1111-1251-0177 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
250 |
Cleandro Pires de Albuquerque |
2020-05-11 |
| A phase II, randomized, open-label clinical study to assess safety and efficacy of masitinib in combination with isoquercetin in the treatment of hospitalized patients with moderate and severe COVID-19 |
Coronavirus disease 19 infection |
isoquercetin plus masitinib |
CSF-1 antagonist, FGF3 receptor antagonist, Fyn tyrosine kinase inhibitor, Kit tyrosine kinase inhibitor, Lyn tyrosine kinase inhibitor, PDGF receptor antagonist, Protein tyrosine kinase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
AB Science SA |
|
France |
2020-05-06 |
|
AB20001 |
Phase 2 Clinical |
Recruiting |
1 |
|
200 |
|
2020-05-08 |
| A study to assess the efficacy of a imiquimod cream with hydroxychloroquine for primary and secondary prophylaxis of subjects with COVID19 infection |
Coronavirus disease 19 infection |
hydroxychloroquine plus imiquimod |
TLR-7 agonist |
|
University of Texas System |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-05-08 |
| Clinical trial on the efficacy of tocilizumab in modifying the inflammatory parameters of patients with COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
tocilizumab (intravenous), Roche/Chugai alone |
IL-6 receptor antagonist, IL-6 receptor modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal |
|
Spain |
2020-05-04 |
|
2020-002032-69, COVITOZ-01 |
Phase 2 Clinical |
Recruiting |
1 |
|
78 |
Departamento de Ensayos Clínicos |
2020-05-11 |
| ANA-COVID-GEAS: Clinical Trial of the Use of Anakinra (Anti-IL-1) in Cytokine Storm Syndrome (CSS) Secondary to COVID-19 |
Coronavirus disease 19 infection, Systemic inflammatory response syndrome, Viral pneumonia |
anakinra alone, standard treatment alone |
Type I IL-1 receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fundación Pública Miguel Servet |
Instituto de Salud Carlos III |
Spain |
2020-04-28 |
|
2020-001825-29, ANA-COVID-GEAS, ANA-COVID-GEAS |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
|
180 |
RUTH GARCIA |
2020-05-11 |
| Anxiety and depression during COVID-19 in India |
Anxiety disorder, Coronavirus disease 19 infection, Depression |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Max Super Speciality Hospital |
|
India |
2020-04-24 |
|
CTRI/2020/04/024784 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1000 |
Dr Sameer Malhotra, Sameer Malhotra, Shreya Singhal |
2020-05-11 |
| A study to assess the effect of Ternatin-4 in patients with Covid-19 |
Coronavirus disease 19 infection |
Ternatin-4 alone |
|
|
University of California San Francisco |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-05-07 |
| SoDi: Neuroendocrine mechanisms, Social isolation and psychobiological stress during the COVID-19 pandemic |
Acute stress disorder, Coronavirus disease 19 infection, Social phobia |
psychotherapeutical counselling alone, smartphone application alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Heidelberg |
|
Germany |
2020-04-03 |
|
DRKS00021671, S-214/2020, SoDi |
Phase Not Applicable |
Recruiting |
1 |
|
200 |
Ekaterina Schneider, Monika Eckstein |
2020-05-11 |
| A study to assess the effect of zotatifin in patients with Covid-19 |
Coronavirus disease 19 infection |
zotatifin alone |
Eukaryotic initiation factor 4A-I inhibitor |
|
University of California San Francisco |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-05-08 |
| COVID-19 DETOUR: Detection of a delayed Treatment of urgent ophthalmologic Treatment during the SARS-CoV-2 pandemic (COVID-19) |
Coronavirus disease 19 infection, Ocular disease |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universitatsklinikum Schleswig-Holstein Campus Kiel |
Klinik für Augenheilkunde, Germany |
Germany |
2020-05-08 |
|
20-477, COVID-19 DETOUR, DRKS00021630 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
30 |
Christoph Ehlken |
2020-05-11 |
| Control of inflammatory parameters with fish oil in parenteral nutrition |
Coronavirus disease 19 infection, Respiratory tract infection |
Variable regimens including ClinOleic , Nutriflex Lipid special , Olimel N9 , Omegaflex special , Omegaven , Smofkabiven , Smoflipid |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Vall D'Hebron |
|
Spain |
2020-04-26 |
|
01-2020, 2020-000705-86 |
Phase 4 Clinical |
Recruiting |
1 |
|
117 |
DAVID BERLANA, David Berlana |
2020-05-11 |
| EMBELLIE: Barrier Measures to Limit COVID-19 Nosocomial Transmission: a Cross-sectional Evaluation |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital, Montpellier |
|
France |
2020-04-01 |
2020-12-30 |
EMBELLIE, NCT04376944, RECHMPL20_0261 |
Phase Not Applicable |
Recruiting |
1 |
8 Months |
300 |
Alain MAKINSON, MCU-PH, Marie Bistoquet, MB, Marie Bistoquet, MD |
2020-05-08 |
| CORTIVID: Early Treatment Of Pneumonia COVID-19 With Glucocorticoids: Randomized, Controlled Clinical Trial |
Coronavirus disease 19 infection, Viral pneumonia |
methylprednisolone alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fundación Pública Miguel Servet |
Centro De Investigación Biomédica En Red De Enfermedades Neurodegenerativas |
Spain |
2020-04-30 |
|
2020-001827-15, CORTIVID, CORTIVID |
Phase 3 Clinical |
Recruiting |
1 |
|
72 |
CLINICAL TRIAL UNIT |
2020-05-11 |
| Heparin-SARS-CoV2: Impact of the use of low molecular weight heparins (LMWH), at prophylactic versus intermediate doses, on SARS-CoV2 infection (COVID-19) |
Coronavirus disease 19 infection |
enoxaparin sodium alone |
Low molecular weight heparin |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fundacion Neumosur |
|
Spain |
2020-05-04 |
|
2020-001891-14, Heparin-SARS-CoV2, Heparin-SARS-CoV2 |
Phase 2 Clinical |
Recruiting |
1 |
|
140 |
Alejandro |
2020-05-11 |
| MindCOVID: Risk Factors for Anxiety and Depression Among Pregnant Women During the COVID-19 Pandemic |
Anxiety disorder, Coronavirus disease 19 infection, Depression |
|
|
Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Zelazna Medical Centre, LLC |
American University of Beirut Medical Center, Central Clinical Hospital of the Internal Affairs and Administration Ministry, Chang Gung University, Charite University, Charles University, Chinese University of Hong Kong, Fundación Para la Investigación y el Desarrollode la Medicina Materno-Fetal y Neonatal “iMaterna”, Hopital Necker Enfants Malades, Karolinska Institutet, Medical Center of Postgraduate Education, Meir Medical Center, Nicolaus Copernicus University, Polish Academy of Sciences, Pomeranian Medical University, Royal Prince Alfred Hospital, Taiji Clinic, Universita degli Studi di Brescia, University of Medicine, Tirana, University of Tromso, Wayne State University |
Italy, Spain, Lebanon, Taiwan, Germany, Czech Republic, Hong Kong, Poland, Israel, Albania, Australia, France, Sweden, Norway, US |
2020-05-01 |
2020-10-31 |
MATERNAL AXIETY AND COVID-19, MindCOVID, NCT04377412 |
Phase Not Applicable |
Recruiting |
16 |
6 Months |
8500 |
Anna Kajdy, Anna Kajdy, MD, PhD, Artur Pokropek, PhD, Professor, Barbara Baranowska, PhD, RM, Dariusz Borowski, MD, PhD, Dorota Sys, PhD, Equal Chen, Ewa Andersson, RNM, PhD, Federico Prefumo, MD, PhD, Ganesh Acharya, MD, PhD, FRCOG, Professor, Ganesh Archaya, MD, PhD, Professor, Gihad Chalouhi, MD, PhD, Heidi Tiller, MD, PhD, Jade Harris, MD, Jan Modzelewski, MD, Jon Hayett, Professor, Jon Hyett, Karine Stiberg Birkelund, Ksenia Olisova, MD, MPH, Laurent J Salomon, MD, PhD, Laurent J Salomon, MD, PhD, Professor, Liona C Poon, MBBS, MRCOG, Professor, Maria del Mar Gil Mira, MD, PhD, Maya Ben-Zion, MD, Michał Rabijewski, MD, PhD, Professor, Orion Gliozheni, MD, Pavel Calda, MD, MSc, Professor, Roksana Lewandowska, MD, Sebastian Kwiatkowski, MD, PhD, Simone Schwank, PhD M.S. M.A. Msc. Clinical Ps, Solrun Rasmussen, Sonia Hassan, MD, Stefan Verlohren, MD, Professor, Stepan Feduniw, MD, Steven Shaw, Tal Biron-Shental, MD, Tung-Yao Chang, MD, M Med Sci, Urszula Ajdacka, MD, pavel Calda, MD, MSc. |
2020-05-11 |
| Tocilizumab Versus Methylprednisolone in the Cytokine Release Syndrome of Patients With COVID-19 |
Coronavirus disease 19 infection, Inflammatory disease |
tocilizumab alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Sao Domingos |
|
Brazil |
2020-05-31 |
2020-11-30 |
COVID-19 HSD, NCT04377503 |
Phase 2 Clinical |
Not yet recruiting |
1 |
6 Months |
40 |
HUGO C LIMA, MD, JOSE A AZEVEDO, MD, PhD, PEDRO B FROTA, MD |
2020-05-12 |
| Use of the Nasal Cannula During COVID-19 |
Coronavirus disease 19 infection |
low flow nasal cannula alone |
|
Healthy volunteers accepted |
Asociación de Anestesia Analgesia y Reanimación de Buenos Aires (AAARBA) |
|
Argentina |
2020-04-30 |
2020-09-30 |
NASAL CANNULAS FLOW RATE, NCT04376580 |
Phase Not Applicable |
Recruiting |
1 |
5 Months |
100 |
Carolina Frederico |
2020-05-08 |
| Parental Stress During the COVID-19 Pandemic and Its Association With Depression and Anxiety |
Acute stress disorder, Coronavirus disease 19 infection, Depression, Generalized anxiety disorder |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Oslo |
Modum Bad, Oslo and Akershus University College of Applied Sciences |
Norway |
2020-03-31 |
2020-04-07 |
NCT04377074, REK125510(3) |
Phase Not Applicable |
Completed |
1 |
|
2880 |
Asle Hoffart, PhD, Miriam Sinkerud Johnson, PhD, Nora Paulsen Skjerdingstad, Omid Ebrahimi, Sverre Urnes Johnson, PhD |
2020-05-11 |
| Fluoxetine to Reduce Intubation and Death After COVID19 Infection |
Coronavirus disease 19 infection |
fluoxetine hydrochloride alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The University of Toledo Health Science Campus |
|
US |
2020-05-01 |
2021-10-20 |
FRIDA COVID19, NCT04377308 |
Phase 4 Clinical |
Recruiting |
0 |
17 Months |
2000 |
Cheryl McCullumsmith, MD PhD, Cheryl Mccullumsmith |
2020-05-08 |
| FORECAST: Finding Out if COVID-19 Infection Can be predicted by Changes in Smell and/or Taste |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University College London |
|
UK |
2020-04-23 |
2020-12-23 |
132311, 20/HRA/1879, FORECAST, NCT04377815 |
Phase Not Applicable |
Recruiting |
2 |
8 Months |
500 |
Alisia Carnemolla, PhD, Rachel L Batterham, PhD |
2020-05-07 |
| The Use of Tocilizumab in the Management of Patients Who Have Severe COVID-19 With Suspected Pulmonary Hyperinflammation |
Coronavirus disease 19 infection, Hypoxia, Lung inflammation, Respiratory failure, Viral pneumonia |
tocilizumab (intravenous), Roche/Chugai alone |
IL-6 receptor antagonist, IL-6 receptor modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hadassah Medical Organization |
Sheba Medical Center, Wolfson Medical Center |
Israel |
2020-04-08 |
2021-05-08 |
0224-20-HMO-CTIL, NCT04377750 |
Phase 4 Clinical |
Recruiting |
4 |
13 Months |
500 |
Eithan Galun, Prof., Galia Rahav, Prof., Juli Benbenisty, MPH, Reuven Pizov, Prof., Shlomo Maayan, PROF, Yasmin Meir, Dr. |
2020-05-14 |
| COVID-Milit: A Study of Hydroxychloroquine and Zinc in the Prevention of COVID-19 Infection in Military Healthcare Workers |
Coronavirus disease 19 infection |
hydroxychloroquine plus zinc |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Hopital Militaire Principal d'instruction de Tunis |
Dacima Consulting, UR17DN02 : Autoimmune Diseases Research Unit |
Tunisia |
2020-05-04 |
2020-07-31 |
COVID-Milit, NCT04377646, TN2020-NAT-INS-38, UR17DN02-001 |
Phase 3 Clinical |
Not yet recruiting |
1 |
2 Months |
660 |
Faida Ajili, MD, Neja Stambouli, PhD, Nejla Mrabet, PhD, Nejla Stambouli, PhD |
2020-05-12 |
| OSCAR: Investigating Otilimab in Patients With Severe Pulmonary COVID-19 Related Disease |
Coronavirus disease 19 infection, Lung disease, Viral pneumonia |
otilimab alone, standard of care alone |
GM-CSF receptor modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
GlaxoSmithKline plc |
|
|
2020-05-18 |
2020-12-20 |
214094, NCT04376684, OSCAR |
Phase 2 Clinical |
Not yet recruiting |
0 |
7 Months |
800 |
EU GSK Clinical Trials Call Center, GSK Clinical Trials, US GSK Clinical Trials Call Center |
2020-05-11 |
| PRED ICU COVID19: Predicting the Need for Intubation in Hospitalized COVID-19 Patients |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Central Hospital, Nancy, France |
|
France |
2020-05-31 |
2020-11-30 |
2020-A01076-33, NCT04376879, PRED ICU COVID19 |
Phase Not Applicable |
Not yet recruiting |
2 |
6 Months |
384 |
Antoine KIMMOUN, MD-PhD, Jean Damien RICARD, MD-PhD, Julie JOSSE, PhD, Patrick ROSSIGNOL, MD-PhD |
2020-05-11 |
| Human Convalescent Plasma for High Risk Children Exposed or Infected With SARS-CoV-2 (COVID-19) |
Coronavirus disease 19 infection |
anti-SARS-CoV-2 human convalescent plasma alone |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Johns Hopkins University |
|
US |
2020-05-18 |
2022-05-18 |
IRB00247557, NCT04377672 |
Phase 1 Clinical |
Not yet recruiting |
0 |
24 Months |
30 |
Mary Katherine Brosnan, Oren Gordon, MD, Sanjay K Jain, MD |
2020-05-11 |
| COVID-CTPRED: Prediction of Clinical Course in COVID-19 Patients |
Coronavirus disease 19 infection |
computed tomography alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire de Saint Etienne |
Centre National de la Recherche Scientifique (CNRS), INSERM, Institut National Des Sciences Appliquées, Universite Jean Monnet, University of Lyon |
France |
2020-03-01 |
2020-09-30 |
20CH096, 20CH109, COVID-CTPRED, NCT04377685 |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
800 |
Beatrice DEYGAS, Pierre CROISILLE, PhD |
2020-05-13 |
| PiCCOVID: Extra Vascular Lung Water and Pulmonary Permeability in Critically Ill Patients With SARS-CoV-2 (COVID-19) |
Coronavirus disease 19 infection |
transpulmonary thermodilution alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital, Montpellier |
|
France |
2020-04-01 |
2020-09-30 |
NCT04376905, PiCCOVID, RECHMPL20-0193 |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
30 |
Fanny Garnier, chef de clinique, Kada KLOUCHE, MD PhD |
2020-05-08 |
| RUXCOVID-DEVENT: Assessment of Efficacy and Safety of Ruxolitinib in Participants With COVID-19-Associated ARDS Who Require Mechanical Ventilation |
Coronavirus disease 19 infection, Respiratory distress syndrome |
Standard of care alone, ruxolitinib (oral, myeloproliferative disorders), Incyte/Novartis alone |
Jak1 tyrosine kinase inhibitor, Jak2 tyrosine kinase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Incyte Corp, Novartis AG |
|
US |
2020-05-08 |
2020-07-29 |
INCB 18424-369, NCT04377620, RUXCOVID-DEVENT |
Phase 3 Clinical |
Recruiting |
0 |
2 Months |
500 |
Incyte Corporation Call Center (US) |
2020-05-11 |
| Mesenchymal Stem Cells (MSCs) in Inflammation-Resolution Programs of Coronavirus Disease 2019 (COVID-19) Induced Acute Respiratory Distress Syndrome (ARDS) |
Coronavirus disease 19 infection, Respiratory distress syndrome |
allogeneic bone marrow-derived human mesenchymal stem (stromal) cells (MSCs) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Tubingen |
|
Germany |
2020-05-31 |
2021-02-28 |
NCT04377334, RESCOVID |
Phase 2 Clinical |
Not yet recruiting |
1 |
9 Months |
40 |
Peter Rosenberger, MD, Peter Rosenberger, Prof., Valbona Mirakaj, Prof. |
2020-05-11 |
| CoronaWatch: Early Detection of Cardiovascular Risks in COVID-19 Via SmartWatch |
Cardiovascular disease, Coronavirus disease 19 infection, Heart arrhythmia |
Apple watch series 5 alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Heidelberg |
Deutsche Herzstiftung eV, Freunde und Förderer der Kardiologie Heidelberg, Klaus Tschira Stiftung GmbH |
Germany |
2020-04-15 |
2020-07-31 |
CORONAWATCH, CoronaWatch, NCT04376853 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
50 |
Benjamin Meder, Prof. Dr. |
2020-05-12 |
| ECHOVID-19: The Role of Ultrasound in COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Gentofte |
|
Denmark |
2020-03-31 |
2021-03-01 |
ECHOVID-19, H-20021500, NCT04377035 |
Phase Not Applicable |
Recruiting |
1 |
11 Months |
1000 |
Tor Biering-Sørensen, MD, PhD, MPH, Tor Biering-sørensen, MD, PhD, MPH |
2020-05-11 |
| PANDEMIC study: Patient’s knowledge And behavior oN the COVID-19 disease and as DEterMInants of Contamination |
Coronavirus disease 19 infection |
questionnaires alone |
|
|
Franciscus Gasthuis & Vlietland |
|
Netherlands |
2020-04-22 |
2020-08-21 |
NL8563, PANDEMIC study |
Phase Not Applicable |
Recruiting |
1 |
4 Months |
170 |
Hanna van der Valk |
2020-05-12 |
| Bioelectric Impedance Analysis in COVID-19 positive patients. A prospective prevalence study |
Coronavirus disease 19 infection |
Bioelectric Impedance Analysis alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ziekenhuis Gelderse Valle |
|
Netherlands |
2020-04-01 |
2020-04-30 |
NL8562 |
Phase Not Applicable |
No longer recruiting |
1 |
1 Month |
50 |
Rianne Slingerland |
2020-05-12 |
| Safe Return to Regular Clinical Operation After COVID-19 Pandemic |
Coronavirus disease 19 infection |
ARCHITECT i2000SR system alone, RealStar SARS-CoV-2 RT-PCR Kit RUO (Altona Diagnostics) alone, SARS-CoV-2 IgG assay kit (Abbott Diagnostics) alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
King Fahad Specialist Hospital Dammam |
|
Saudi Arabia |
2020-05-17 |
2020-12-30 |
KFSH-ONC-02, NCT04377802 |
Phase Not Applicable |
Not yet recruiting |
1 |
7 Months |
400 |
Fahad Ibnshamsah, MD, Hani Al Hashmi, MD, Salem Ghandourah, PhD |
2020-05-08 |
| Convalescent Plasma Collection and Treatment in Pediatrics and Adults |
Coronavirus disease 19 infection, Dyspnea |
convalescent plasma alone |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
West Virginia University |
|
US |
2020-04-16 |
2021-03-30 |
2004965705, NCT04376034 |
Phase 3 Clinical |
Recruiting |
0 |
11 Months |
240 |
Brian Peppers, DO, PhD, Lisa Giblin Sutton, PharmD |
2020-05-07 |
| Attention Bias Modification for Reducing Health Anxiety During the Coronavirus Pandemic |
Anxiety disorder, Coronavirus disease 19 infection |
Attention Bias Modification (ABM) alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tel Aviv University |
|
Israel |
2020-04-23 |
2020-04-30 |
NCT04365972, TAU-COVID-19 |
Phase Not Applicable |
Completed |
1 |
|
20 |
Yair Bar-Haim, PhD |
2020-05-11 |
| Tocilizumab for Prevention of Respiratory Failure in Patients With Severe COVID-19 Infection |
Coronavirus disease 19 infection, Respiratory failure |
tocilizumab alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Memorial Sloan-Kettering Cancer Center |
|
US |
2020-05-01 |
2021-05-01 |
20-185, NCT04377659 |
Phase 2 Clinical |
Recruiting |
0 |
12 Months |
40 |
Ann Jubowski, MD, Boglarka Gyurkocza, MD |
2020-05-11 |
| COVID: Survey: COVID-19 Patients Managed in the Operating Theatre of Belgian Hospitals |
Coronavirus disease 19 infection |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Clinique Universitaires Saint-Luc, Universite Catholique de Louvain |
Society for Anesthesia and Resuscitation of Belgium |
Belgium |
2020-04-06 |
2020-09-30 |
COVID, COVID-ANESTHESIO, NCT04376398 |
Phase Not Applicable |
Recruiting |
1 |
5 Months |
200 |
Mona Momeni, MD, PhD, Vincent Bonhomme, MD, PhD |
2020-05-12 |
| COVID-BCG: Efficacy of BCG Vaccination in the Prevention of COVID19 Via the Strengthening of Innate Immunity in Health Care Workers |
Coronavirus disease 19 infection |
VACCIN BCG AJVaccines alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assistance Publique Hopitaux de Paris |
French Health Ministry |
France |
2020-04-28 |
2021-02-11 |
2020-001678-31, APHP200462, COVID-BCG, NCT04384549 |
Phase 3 Clinical |
Recruiting |
2 |
9 Months |
1120 |
Ahlam SAAD, Anne RADENNE, Camille LOCHT, Professor, Odile LAUNAY, Professor |
2020-05-13 |
| HPI-COVID-19: Host-pathogen Interactions During SARS-CoV-2 Infection |
Coronavirus disease 19 infection, Viral pneumonia |
biological sampling alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Hospices Civils De Lyon |
|
France |
2020-05-05 |
2021-06-05 |
2020-A01102-37, 69HCL20-0342, HPI-COVID-19, NCT04376476 |
Phase Not Applicable |
Recruiting |
12 |
13 Months |
450 |
Aurélie PORTEFAIX, MD,PhD, Christèle GRAS-LE-GUEN, PU,PH, Clémence JARRASSE, MD,PhD, Cyrille CONFAVREUX, PU,PH, Etienne JAVOUHEY, PU,PH, Florent VALOUR, PhD, Guillaume MORTAMET, MD,PhD, Hervé LOBBES, MD,PhD, Hugues PATURAL, PU,PH, Marie BAILS-DE-GEORGES, MD,PhD, Nicolas JORAM, MD,PhD, Philippe REBAUD, MD,PhD, Romain BASMACI, PU,PH, Sébastien COURAUD, PU,PH, Thomas BARBA, MD,PhD, Thomas JULLIEN, PhD, Tiphanie Ginhoux, Vincent COTTIN, PU,PH, Yvan JAMILLOUX, PhD |
2020-05-11 |
| COVID-19 - Quality of Life After Infection |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Chinese University of Hong Kong |
|
Hong Kong |
2020-05-05 |
2022-04-30 |
NCT04377464, NTEC-2020-0227 |
Phase Not Applicable |
Not yet recruiting |
2 |
23 Months |
200 |
Colin Graham, MD, MPH, Joseph Walline, MD |
2020-05-08 |
| SLO-COVID-19: Slovenian National COVID-19 Prevalence Study |
Coronavirus disease 19 infection |
nasopharyngeal sampling alone |
|
|
University Of Ljubljana |
|
Slovenia |
2020-04-20 |
2020-12-31 |
NCT04376996, SLO-COVID-19, ULMF2020-COVID-19 |
Phase Not Applicable |
Recruiting |
1 |
8 Months |
3000 |
Mario Poljak, MD, PhD, Polona Maver Vodicar, MD, PhD |
2020-05-08 |
| Exchange Transfusion Versus Plasma From Convalescent Patients With Methylene Blue in Patients With COVID-19 |
Coronavirus disease 19 infection, Lung disease |
antihistamine therapy alone, standard of care alone, Variable regimens including convalescent plasma , epinephrine , low-molecular-weight heparin , methyl prednisone , methylene blue , packed washed RBC |
Adrenergic receptor agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Ain Shams University |
|
Egypt |
2020-05-05 |
2020-06-01 |
FMASU P22/2020, NCT04376788 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
15 |
Essam A Hassan, MD, Mohamed M Moussa, Mohamed M Moussa, MD |
2020-05-11 |
| THROMBCOVID2: Thrombo Embolic Events in Hospitalized Patients With Covid-19 Serious Acute Pneumopathy |
Coronavirus disease 19 infection, Thromboembolism, Viral pneumonia |
blood sampling alone, venous ultrasound alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire D Amiens |
|
France |
2020-05-04 |
2020-11-30 |
2020-A01084-35, NCT04377490, PI2020_843_0040, THROMBCOVID2 |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
100 |
Claire Andrejak, Pr, Julien Maizel, Pr, Michel Slama, Pr, Philippe Lanoix, Pr, Simon Soudet, MD, Valery Salle, MD, Yoann Zerbib, MD |
2020-05-11 |
| COVID-19 infections in health care workers |
Coronavirus disease 19 infection |
|
|
|
Franciscus Gasthuis & Vlietland |
|
Netherlands |
2020-05-01 |
2020-12-31 |
NL8570, R20.030 |
Phase Not Applicable |
Not yet recruiting |
1 |
8 Months |
300 |
Hans Koeleman |
2020-05-08 |
| ReCOVER: Evaluation of a remote monitoring smartphone application and care model of COVID-19 patients in the community |
Coronavirus disease 19 infection |
TCC-COVID alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Health South Eastern Sydney Local Health District, University of New South Wales |
|
Australia |
2020-04-28 |
2021-04-30 |
ACTRN12620000524998, ReCOVER |
Phase Not Applicable |
Not yet recruiting |
4 |
12 Months |
2000 |
Dr Sze-Yuan Ooi |
2020-05-14 |
| A clinical study of CardiALLO cell therapy for the treatment of COVID-19 infection related Acute Respiratory Distress Syndrome |
Coronavirus disease 19 infection, Respiratory distress syndrome |
CardiALLO cell therapy alone |
|
|
BioCardia Inc |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-05-08 |
| A Study of the Safety and Efficacy of Ciclesonide in the Treatment of Non-hospitalized COVID-19 Patients |
Coronavirus disease 19 infection |
ciclesonide (metered dose inhaler), Teijin/Covis/AstraZeneca alone |
Glucocorticoid receptor agonist |
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Covis Pharma Sarl |
|
|
2020-05-26 |
2020-12-01 |
ALV-020-001, NCT04377711 |
Phase 3 Clinical |
Not yet recruiting |
0 |
6 Months |
400 |
|
2020-05-08 |
| COVID-19 Health Messaging Efficacy and Its Impact on Public Perception, Anxiety and Behavior |
Anxiety disorder, Coronavirus disease 19 infection, Psychiatric disorder |
health messaging alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Milton S. Hershey Medical Center |
Huck Institutes of the Life Sciences, The College of Healthcare Information Management Executives (CHIME), The Department of Family and Community Medicine, Penn State College of Medicine, The Social Science Research Institute, US |
US |
2020-04-09 |
2020-05-31 |
NCT04377581, STUDY00014798 |
Phase Not Applicable |
Recruiting |
0 |
1 Month |
25000 |
Erin McGinley, Erin McGinley, MD, JD, Robert P Lennon, MD, JD, Sherry Tate |
2020-05-11 |
| NCoS: Neonatal CoVID-19 Study to evaluate the population health impacts of COVID-19 in mothers and their newborn infants cared for in tertiary and non-tertiary hospitals in Australia |
Coronavirus disease 19 infection |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Hunter New England Health |
Sydney Childrens Hospital |
Australia |
2020-05-01 |
2022-11-30 |
ACTRN12620000527965, NCoS, U1111-1250-9525 |
Phase Not Applicable |
Not yet recruiting |
7 |
31 Months |
1000 |
Dr Javeed Travadi |
2020-05-14 |
| PET/CT Imaging in COVID-19 Patients |
Coronavirus disease 19 infection, Lung injury |
18F-alphavbeta6-BP alone, computed tomography (CT) alone, positron emission tomography (PET) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of California Davis |
|
US |
2020-05-31 |
2022-05-31 |
1592298, NCT04376593 |
Phase 0 Clinical |
Recruiting |
0 |
24 Months |
10 |
Julie L. Sutcliffe |
2020-05-07 |
| COVIDECOLE: Incidence of COVID-19 in School Children |
Coronavirus disease 19 infection |
RT-PCR alone |
|
Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs) |
Fondation Lenval |
|
France |
2020-05-15 |
2020-09-30 |
20-HPNCL-02, COVIDECOLE, NCT04377737 |
Phase Not Applicable |
Not yet recruiting |
1 |
4 Months |
914 |
Anne-Laure HERISSE, Antoine TRAN, Antoine TRAN, MD, Diane DEMONCHY, Hervé HAAS, Hervé HAAS, MD, Lisa GIOVANNINI-CHAMI, Sarah MARCHAL |
2020-05-08 |
| CoV-ETH: Spread And Course Of COVID-19 Infections |
Coronavirus disease 19 infection |
serological testing alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
ETH Zurich |
|
Switzerland |
2020-04-27 |
2021-06-30 |
20-05, CoV-ETH, NCT04377724 |
Phase Not Applicable |
Recruiting |
1 |
14 Months |
3000 |
Christoph Kolling, MD, Goldhahn Jorg, Jörg Goldhahn, MD |
2020-05-11 |
| Hemoglobin Concentration on COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
Nevsehir Public Hospital |
Konya Training And Research Hospital |
Turkey |
2020-05-01 |
2020-05-30 |
145/2020, NCT04377607 |
Phase Not Applicable |
Recruiting |
1 |
|
200 |
Ahmet Yasin, Mehmet Akif Yazar, Yasin Tire |
2020-05-12 |
| CONCOR-KIDS: Efficacy of Human Coronavirus-immune Convalescent Plasma for the Treatment of COVID-19 Disease in Hospitalized Children |
Coronavirus disease 19 infection |
COVID-19 convalescent plasma (C19-CP) alone, standard of care alone |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
C17 Council, Hospital for Sick Children |
|
Canada |
2020-05-01 |
2022-05-01 |
1000070143, CONCOR-KIDS, NCT04377568 |
Phase 2 Clinical |
Not yet recruiting |
12 |
24 Months |
100 |
Anne Pham-Huy, Ari Joffe, Carol Portwine, Christoph Licht, Geoff Cuvelier Cuvelier, Julia Upton, Julia Upton, MD, MPH, Julie Autmizguine, Karina Top, Kathy Brodeur-Robb, Kirk Leifso, Kyla Hildebrand, Nancy Nashid, Peter Gill, MD, Rupeena Purewal, Sergio Fanella, Tammie Dewan |
2020-05-07 |
| Quality of Life and Patient-centered Outcomes After Hospitalization for COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
extracorporeal membrane oxygenation alone, high flow nasal cannula alone, mechanical ventilation alone, nasal catheter alone, noninvasive ventilation alone, oxygen alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Instituto de Educação e Pesquisa do Hospital Moinhos de Vento |
Beneficencia Portuguesa of Sao Paulo, Brazilian Clinical Research Institute, Brazilian Research In Intensive Care Network, Hospital Alemao Oswaldo Cruz, Hospital do Coracao, Sociedade Beneficente Israelita Brasileira Hospital Albert Einsten, Sociedade Beneficiente De Senhoras Hospital Sirio Libanes |
Brazil |
2020-06-15 |
2021-09-15 |
COALITION COVID-19: LONG-TERM, NCT04376658 |
Phase Not Applicable |
Not yet recruiting |
1 |
15 Months |
1000 |
Maicon Falavigna, MD, Regis G Rosa, MD |
2020-05-12 |
| Neuro-Covid: COVID-19 Prevalence and Cognitive Deficits in Neurological Patients |
Cognitive disorder, Coronavirus disease 19 infection, Epilepsy, Neurological disease, Seizure disorder, Stroke |
COVID-19 PCR swab test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Aarhus University Hospital |
|
Denmark |
2020-05-07 |
2022-06-30 |
NCT04377425, NEURO-COVID-19, Neuro-Covid |
Phase Not Applicable |
Not yet recruiting |
4 |
25 Months |
100 |
Boris Modrau, Boris Modrau, MD, Grethe Andersen, MD, Grethe Andersen, MD, DMSc, Lene Rosendahl, MD, Morten Stilund, MD, PhD, Rolf Blauenfeldt, MD |
2020-05-11 |
| Observational Study Concerning COVID-19 Infection in Transplanted Kidney, Pancreas or Pancreatic Islet Patients |
Coronavirus disease 19 infection, Kidney transplantation, Pancreas transplantation, Transplantation |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
IRCCS San Raffaele |
|
Italy |
2020-05-04 |
2020-05-18 |
COVID-19 MITRA, NCT04377776 |
Phase Not Applicable |
Recruiting |
1 |
|
700 |
Antonio Secchi, Federica Pazzi, Paola Maffi, Rossana Caldara |
2020-05-14 |
| Effect of Quercetin on Prophylaxis and Treatment of COVID-19 |
Coronavirus disease 19 infection |
Quercetin alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Istanbul Bakirkoy Maternity and Children Diseases Hospital |
|
Turkey |
2020-03-20 |
2020-08-31 |
KSSEAH--0058, NCT04377789 |
Phase Not Applicable |
Recruiting |
2 |
5 Months |
50 |
Hasan Onal, Hasan Onal, Professor, Seda Yilmaz Semerci |
2020-05-09 |
| SEROCOV: Development and Evaluation of Serological Assays for COVID-19 |
Coronavirus disease 19 infection |
serological assay alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assistance Publique Hopitaux de Paris |
|
France |
2020-05-31 |
2020-10-31 |
20MWI-SEROCOV, NCT04377763, SEROCOV |
Phase Not Applicable |
Not yet recruiting |
1 |
5 Months |
500 |
Marie-Anne RAMEIX-WELTI, MD, PhD |
2020-05-11 |
| COLOR-19: COVID-19 Pneumonitis Low Dose Lung Radiotherapy |
Coronavirus disease 19 infection, Viral pneumonia |
Single fraction whole lung radiotherapy (0.7 Gy) alone |
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia |
|
Italy |
2020-05-10 |
2022-07-23 |
COLOR-19, NCT04377477, NP 4097 |
Phase Not Applicable |
Recruiting |
1 |
26 Months |
30 |
Davide Tomasini, MD, Stefano M Magrini, Prof |
2020-05-12 |
| COWAIT: Assessment of the Impact of COVID-19 on Transplant Patients and on Patients Awaiting Transplantation |
Coronavirus disease 19 infection, Heart transplantation, Kidney transplantation, Liver transplantation, Lung transplantation, Pancreas transplantation |
patient-completed survey alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital, Bordeaux |
Societe Francophone de Transplantation |
France |
2020-05-15 |
2020-12-15 |
CHUBX 2020/19, COWAIT, NCT04376775 |
Phase Not Applicable |
Not yet recruiting |
1 |
7 Months |
2000 |
Lionel COUZI, Pr |
2020-05-12 |
| A clinical study of JS-016 in treatment of patients with COVID-19 |
Coronavirus disease 19 infection |
JS-016 alone |
COVID19 Spike glycoprotein inhibitor |
|
Eli Lilly & Co, Shanghai Junshi Biosciences Co Ltd |
|
US |
2020-12-31 |
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-05-08 |
| Surgical Telemedicine in the COVID-19 Pandemic Era |
Coronavirus disease 19 infection |
telemedicine program alone |
|
Healthy volunteers accepted, Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
University of Colorado, Denver, US |
|
US |
2020-06-01 |
2020-12-31 |
20-1177, NCT04376710 |
Phase Not Applicable |
Not yet recruiting |
0 |
7 Months |
100 |
|
2020-05-07 |
| A study to evaluate REGN-COV2 for the prevention and treatment of SARS-CoV-2 |
Coronavirus disease 19 infection |
REGN-COV2 alone |
|
|
Regeneron Pharmaceuticals Inc |
|
|
2020-06-30 |
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-05-07 |
| COVID-19 MMR: A study to assess the use of MMR vaccine for the treatment of COVID-19 infection |
Coronavirus disease 19 infection |
MMR vaccine alone |
|
|
World Health Organization |
|
|
|
|
COVID-19 MMR |
Phase Not Applicable |
Status not specified |
0 |
|
|
Dr. Larry P. Tilley, Jeff Gold |
2020-05-08 |
| Correlation Between Oxidative Stress Status and COVID-19 Severity |
Coronavirus disease 19 infection, Hypoxia |
ELISA alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shaheed Beheshti Medical University |
|
Iran |
2020-04-20 |
2020-07-01 |
NCT04375137, SBMU.12543 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
90 |
Dalili, Nooshin Dalili, Nooshin Dalili, Dr, nooshin dalili |
2020-05-08 |
| TRIIM-X: Thymus Regeneration, Immunorestoration, and Insulin Mitigation Extension Trial |
Aging, Cancer, Cardiovascular disease, Coronavirus disease 19 infection, Dementia, Diabetes mellitus, Infectious disease, Influenza virus infection |
Variable regimens including DHEA , metformin hydrochloride , somatropin |
AMP activated protein kinase stimulator |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Intervene Immune Inc |
|
US |
2020-10-31 |
2022-10-31 |
NCT04375657, TRIIM-X, TRIIM-X |
Phase 2 Clinical |
Recruiting |
0 |
24 Months |
85 |
Gregory M Fahy, PhD, Robert Brooke |
2020-05-08 |
| Community Pharmacists Behavior During Covid-19 |
Coronavirus disease 19 infection |
face to face interview alone, semi-structured telephone interview alone |
|
|
Damanhour University |
|
Egypt |
2020-05-02 |
2021-04-30 |
NCT04374513, PHARMACISTS AND COVID-19 |
Phase Not Applicable |
Recruiting |
2 |
11 Months |
50 |
Amira Kassem, PhD, Amira Kassem, phD, Asser Ghoneim, phD, Noha El Bassiouny, PhD |
2020-05-07 |
| The effect of addition of selenium to treatment regimen of hospitalized patients with corona on the outcome of disease compared with control group |
Coronavirus disease 19 infection |
antibiotic therapy alone, antiretroviral therapy alone, selenium alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sabzevar University of Medical Sciences |
|
Iran |
2020-05-20 |
|
IR.MEDSAB.REC.1399.017, IRCT20160706028815N5 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
40 |
Afsaneh Kaffash, Fereshteh Ghorat |
2020-05-07 |
| I-SPY COVID: A clinical trial to rapidly identify therapies to treat acute respiratory distress syndrome (ARDS) in critically ill COVID-19 patients |
Coronavirus disease 19 infection, Respiratory distress syndrome |
standard-of-care alone |
|
|
QuantumLeap Healthcare, University of California San Francisco |
|
US |
|
|
I-SPY COVID |
Phase Not Applicable |
Status not specified |
0 |
|
|
Laura Esserman |
2020-05-07 |
| Less Frequency Hemodialysis and COVID-19 |
Coronavirus disease 19 infection, Kidney dialysis |
less-frequency hemodialysis alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Dialisis Madariaga |
|
Argentina |
2020-03-20 |
2021-03-31 |
CORONAVIRUS, NCT04374058 |
Phase Not Applicable |
No longer recruiting |
1 |
12 Months |
50 |
Esteban L Siga, MD |
2020-05-12 |
| A first in human clinical trial of DPX-COVID-19 for the potential prevention of COVID-19 |
Coronavirus disease 19 infection |
DPX-COVID-19 alone |
|
|
McGill University Health Center |
Fonds de solidarité FTQ |
|
2020-07-31 |
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-05-06 |
| Early Short Course Corticosteroids in COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
antibiotic therapy alone, antiviral therapy alone, high-flow nasal cannula therapy alone, mechanical ventilation therapy alone, renal-replacement therapy alone, standard care alone, supportive care alone, Variable regimens including hydroxychloroquine , lopinavir , methylprednisolone , remdesivir , ritonavir |
Coronavirus non structural protein 8 modulator, RNA polymerase modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Henry Ford Health System |
|
US |
2020-03-12 |
2020-04-30 |
HFH IRB # 13739, NCT04374071 |
Phase Not Applicable |
Completed |
0 |
1 Month |
250 |
Dr. Mayur S. Ramesh |
2020-05-08 |
| Level and Predictors of Trauma-symptoms Among Health Workers and Public Service Providers During the COVID-19 Outbreak |
Anxiety disorder, Coronavirus disease 19 infection, Depression, Injury, Post traumatic stress disorder |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Oslo |
Modum Bad |
Norway |
2020-03-31 |
2020-04-07 |
NCT04374097, REK125510(2) |
Phase Not Applicable |
Completed |
1 |
|
1778 |
Asle Hoffart, PhD, Omid Ebrahimi, Sverre Urnes Johnson, PhD |
2020-05-07 |
| PROVID: PROne Positioning in coVID-19 Oxygeno-dependent Patients in Spontaneous Ventilation (PROVID Study) |
Coronavirus disease 19 infection |
Prone positioning alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assistance Publique Hopitaux de Paris |
|
France |
2020-04-30 |
2020-07-31 |
APHP200504, NCT04366856, PROVID |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
500 |
Anatole HARROIS, Anatole HARROIS, MD, Anatole HARROIS, MD, PhD |
2020-05-07 |
| Clinical trial of anti-SARS-CoV-2 antibodies (COVID-19), Formycon for the treatment of Covid-19 |
Coronavirus disease 19 infection |
anti-SARS-CoV-2 antibodies (COVID-19), Formycon alone |
|
|
Formycon AG |
|
|
2021-09-30 |
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-05-08 |
| Pulmonary Rehabilitation in Post-Acute Period of COVID-19 Infection |
Anxiety disorder, Coronavirus disease 19 infection, Depression, Dyspnea, Fatigue, Myalgia |
Pulmonary Rehabilitation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Istanbul Bilgi University |
|
Turkey |
2020-03-11 |
2020-04-26 |
NCT04365738, PR COVID-19 |
Phase Not Applicable |
Completed |
1 |
1 Month |
270 |
Tomri̇s Duymaz |
2020-05-07 |
| Bacterial ACE2: Recombinant Bacterial ACE2 Receptors -Like Enzyme of B38-CAP Could be Promising COVID-19 Infection- and Lung Injury Preventing Drug Better Than Recombinant Human ACE2 |
Coronavirus disease 19 infection, Lung injury |
recombinant bacterial ACE2 receptors -like enzyme of B38-CAP (rbACE2) alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kafrelsheikh University |
|
Egypt |
2020-08-31 |
2020-10-31 |
Bacterial ACE2, NCT04375046, PROPOSED BY MAHMOUD KAZAZZAZ |
Phase 1 Clinical |
Not yet recruiting |
1 |
2 Months |
24 |
M.Sc. Mahmoud Elkazzaz, M.Sc.Biochemistry, M.Sc.Mahmoud Elkazzaz, M.Sc.Biochemistry, Mahmoud Ramadan mohamed Elkazzaz |
2020-05-12 |
| An expanded access for compassionate use program to assess stem cells in the treatment of patients with COVID-19 infection |
Coronavirus disease 19 infection |
stem cells alone |
|
|
GIOSTAR |
|
US |
|
|
|
Phase Not Applicable |
Not yet recruiting |
0 |
|
|
Dr. Prabhat Soni |
2020-05-06 |
| Prehospital Intubation of COVID-19 Patient With Personal Protective Equipment |
Cardiac arrest, Coronavirus disease 19 infection |
Vie Scope laryngoscopy alone, endotracheal intubation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Lazarski University |
Medical University of Bialystok, Poznan University of Medical Sciences, Wroclaw Medical University |
Poland |
2020-03-20 |
2020-05-20 |
INT_EMS_PPE_1, NCT04365608 |
Phase Not Applicable |
Recruiting |
2 |
2 Months |
90 |
Lukasz Szarpak, PhD, Marek Dabrowski, PhD |
2020-05-06 |
| MYOCOVID: Hospital Registry of Acute Myocarditis: Evolution of the Proportion of Positive SARS-COV-2 (COVID-19) Cases |
Coronavirus disease 19 infection, Myocarditis |
CT scan alone, bacteriological test alone, immunological test alone, myocardial MRI alone, myocardial biopsy alone, parasitic tests alone, polymerase chain reaction alone, routine care alone, transthoracic echocardiography alone, viral test alone |
|
|
Centre Hospitalier Universitaire de Toulouse |
|
France |
2020-04-15 |
2021-10-15 |
MYOCOVID, NCT04375748, RC31/20/0139 |
Phase Not Applicable |
Recruiting |
1 |
18 Months |
400 |
Audrey TOMASIK, Clément Delmas |
2020-05-06 |
| RECOVER: Trial to Promote Recovery From COVID-19 With Ivermectin or Endocrine Therapy |
Coronavirus disease 19 infection |
bicalutamide alone, standard of care alone |
Androgen receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sidney Kimmel Comprehensive Cancer Center |
|
US |
2020-06-30 |
2021-06-30 |
COV2003, IRB00249425, NCT04374279, RECOVER |
Phase 2 Clinical |
Not yet recruiting |
0 |
12 Months |
60 |
Aliya Lalji, MD, Catherine H Marshall, MD/MPH, Jeffrey Rothstein, MD/PhD, Lindsey Hayes, MD/PhD, Samuel Denmeade, MD, Shawn Kwatra, MD, Vasan Yegnasubramanian, MD/PhD |
2020-05-06 |
| Early warning model and new biomarker of severe novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
Anhui Provincial Hospital |
|
China |
2020-01-10 |
2020-05-30 |
ChiCTR2000032460 |
Phase 0 Clinical |
No longer recruiting |
1 |
4 Months |
350 |
Meiqiao Chen, Wenting Li |
2020-05-08 |
| COVID19-FOIE National Observatory |
Brain disease, Coronavirus disease 19 infection, Diabetes mellitus, Hepatitis B virus infection, Hepatitis C virus infection, Hepatocellular carcinoma, Hypertension, Liver cirrhosis, Liver disease, Metabolic syndrome X, Obesity, Renal disease |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assistance Publique Hopitaux de Paris |
Association Française pour l’Etude du Foie (AFEF), Societe Nationale Francaise de Gastroenterologie |
France |
2020-05-05 |
2020-12-31 |
IRB00006477, NCT04375670 |
Phase Not Applicable |
Not yet recruiting |
1 |
7 Months |
1000 |
Nathalie Ganne-Carrié, MD-PhD |
2020-05-08 |
| Evaluation effect of indomethacin for Covid19 infection |
Coronavirus disease 19 infection, Viral pneumonia |
indomethacin (Aria Pharmaceutical Company) alone, usual treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Isfahan University of medical Sciences |
|
Iran |
2020-05-08 |
|
IR.MUI.MED.REC.1399.045, IRCT20200427047215N1 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
|
60 |
Ali Darakhshandeh |
2020-05-11 |
| Effects of Mobile App in House Staff Health and Well-being During COVID-19 Pandemic |
Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Sleep disorder |
Calm Meditation App alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Arizona |
|
US |
2020-05-01 |
2020-10-01 |
NCT04374786, TO BE DETERMINED |
Phase Not Applicable |
Not yet recruiting |
0 |
5 Months |
328 |
Kelley Saunders, Kelley T Saunders, MD, Mike Foley, MD, Rachael Smith, DO |
2020-05-07 |
| COR-CARDIO: Drug Safety and the Occurrence of Complications During Hospitalization in Patients With COVID-19 |
Cardiovascular disease, Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Instytut Kardiologii Im Prymasa Tysiaclecia |
|
Poland |
2020-05-05 |
2021-08-24 |
1860/2020, COR-CARDIO, NCT04374110 |
Phase Not Applicable |
Recruiting |
2 |
15 Months |
1000 |
Alekander Prejbisz, Aleksander Prejbisz, MD, PhD, Andrzej Januszewicz, MD, PhD, Piotr Dobrowolski, Piotr Dobrowolski, MD, PhD, Rafal Dabrowski, MD, PhD, Tomasz Hryniewiecki, MD, PhD |
2020-05-07 |
| Treatment of Angiotensin Peptide (1-7) for COVID-19 |
Coronavirus disease 19 infection |
angiotensin peptide (1-7) derived plasma alone, routine treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Istanbul Bakirkoy Maternity and Children Diseases Hospital |
|
Turkey |
2020-04-25 |
2020-09-30 |
KSSEAH--0059, NCT04375124 |
Phase 2 Clinical |
Recruiting |
1 |
5 Months |
20 |
Hasan Onal, Seda Yilmaz Semerci |
2020-05-11 |
| Investigating the efficacy of high dose of glucocorticoid in patients with moderate to severe pneumonia related to COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
national guideline based routine treatment alone, methylprednisolone plus prednisolone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Bagheiat-allah University of Medical Sciences |
|
Iran |
2020-04-20 |
|
IR.BMSU.REC.1399.099, IRCT20080901001165N52 |
Phase 3 Clinical |
Recruiting |
1 |
|
50 |
Ahmad Zarei, Behzad Einollahi, Gholamhosein Alishiri, Parisa Kianpour, Yunes Panahi |
2020-05-08 |
| Therapeutic Plasma Exchange Alone or in Combination With Ruxolitinib in COVID-19 Associated CRS |
Coronavirus disease 19 infection |
Therapeutic Plasma Exchange alone, ruxolitinib alone |
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Prisma Health-Upstate |
|
US |
2020-04-30 |
2021-04-30 |
NCT04374149, PHU COVID-19-001 |
Phase 2 Clinical |
Not yet recruiting |
0 |
12 Months |
20 |
Jan Kueber, RN, Julie Martin, DNP, W. Larry Gluck, MD |
2020-05-08 |
| Anosmia Rehabilitation in Patients Post Coronavirus Disease (COVID 19) |
Coronavirus disease 19 infection, Dysomia, Viral respiratory tract infection |
Nasal irrigation alone, NeilMed Sinus Rinse alone, NeilMed Sinus Rinse bottle alone, Olfactory retraining alone, budesonide plus budesonide (inhaled formulations), AstraZeneca |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Lawson Health Research Institute |
|
Canada |
2020-06-30 |
2021-12-31 |
ANOSMIA_COVID 19, NCT04374474 |
Phase 4 Clinical |
Not yet recruiting |
2 |
18 Months |
75 |
Brian Rotenberg, MD, Janet Knechtel, Khrystyna Ioanidi, MD, Leigh J Sowerby, Leigh J Sowerby, MD, Leigh Sowerby, MD, FRCSC, Sherry Paiva |
2020-05-07 |
| COVID-19 Serology Screening and Strict Protocol in the Endoscopy Unit |
Coronavirus disease 19 infection |
endoscopic examination alone, nucleic acid PCR testing alone, serological screening alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
INSTITUTO ECUATORIANO DE ENFERMEDADES DIGESTIVAS GASTROCLINICA S.A |
|
Ecuador |
2020-04-20 |
2020-06-01 |
IECED-04-15-COVID, NCT04374123 |
Phase Not Applicable |
Recruiting |
1 |
1 Month |
80 |
Carlos A Robles-Medranda, MD, Roberto A Oleas, MD |
2020-05-07 |
| HEROS: COVID-19: Human Epidemiology and Response to SARS-CoV-2 |
Asthma, Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
National Institute of Allergy and Infectious Diseases |
Rho Inc |
US |
2020-05-01 |
2020-12-31 |
DAIT-COVID-19-001, HEROS, NCT04375761 |
Phase Not Applicable |
Recruiting |
0 |
8 Months |
8000 |
Alexandra Connolly, Amanda Cyrus, Andrew Liu, MD, Asel Baatyrbek, Carlos A. Camargo, Jr., MD, DrPH, Christine C. Johnson, PhD, Christine M. Seroogy, MD, Daniel J. Jackson, MD, Daphne Suzin, Dolores Santoyo, Edward Zoratti, MD, Elizabeth Tesson, George T. O'Connor, MD, MS, Gurjit K. Khurana Hershey, MD, PhD, Jen Smith, Kyle Koshalek, Kyra Jones, Leonard B. Bacharier, MD, Marcela Pierce, Meyer Kattan, MD, Nicole Gonzalez, Pamela Groh, Pascuala Pinedo-Estrada, Rebecca Gruchalla, MD, Sherae Hereford, Stephen Teach, MD, Tiffany Ogundipe, Tina V. Hartert, MD, MPH, Zachary Flege |
2020-05-14 |
| COLVID-19: Colchicine in COVID-19: a Pilot Study |
Coronavirus disease 19 infection, Viral pneumonia |
colchicine alone, current care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universita Degli Studi Di Perugia |
|
Italy |
2020-04-18 |
2020-10-31 |
2020-001475-33, COLVID-19, NCT04375202 |
Phase 2 Clinical |
Recruiting |
2 |
6 Months |
308 |
Carlo Scirè, Claudia Diana, Prof Roberto Gerli |
2020-05-07 |
| Clinical Trial to Evaluate the Efficacy and Safety of an Immunomodulatory Therapy for the Treatment of Patients With Moderate to Severe COVID-19 Infection |
Coronavirus disease 19 infection, Viral pneumonia |
metenkefalin acetate + tridecactide acetate (injectable, multiple sclerosis), Farmacija alone, standard of care treatment alone |
ACTH receptor agonist, Adrenocorticotrophic hormone ligand, Opioid growth factor receptor agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Bosnalijek Pharmaceutical & Chemical Industry Joint Stock Co |
|
Bosnia and Herzegovina |
2020-05-01 |
2020-10-31 |
EN-COVCS-01, NCT04374032 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
6 Months |
120 |
Jasna Dzananovic, MPharm, Rusmir Baljic, doc.dr.med |
2020-05-08 |
| COVHYP: Renin-Angiotensin-Aldosterone System Inhibitors, Hypertension, and COVID-19 |
Cancer, Chill, Congestive heart failure, Coronavirus disease 19 infection, Cough, Diabetes mellitus, Dyspnea, Heart disease, Hypertension, Lung malformation, Myalgia, Viral pneumonia |
chest CT-Scan alone, chest X-ray alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Versailles University Hospital |
|
France |
2020-05-01 |
2020-07-01 |
COVHYP, NCT04374695, P20/11_COVHYP |
Phase Not Applicable |
Not yet recruiting |
1 |
2 Months |
700 |
Alisson BERTRAND, Alix PREVOT, Bernard LIVAREK, MD, Cécile LAUREANA, Floriane GILLES, MD, Guillaume ROGER, Jean-Baptiste AZOWA, Jean-François PROST, Jean-Louis GEORGES, MD, MPH, Jean-Paul BERESSI, MD, Joseph SABA, Joséphine SOLTANI, Maeva PASQUALINI, Marie DE TOURNEMIRE, Mehrsa KOUKABI FRADELIZZI, MD, Victorien MONGUILLON |
2020-05-12 |
| A Phase II, Open-Label, Randomized, Controlled Trial to Assess the Safety and Efficacy of Convalescent Plasma to Limit COVID-19 Associated Complications |
Coronavirus disease 19 infection, Respiratory distress syndrome, Sepsis |
convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Max Healthcare Institute Ltd, India |
|
India |
2020-05-09 |
2021-05-09 |
CTRI/2020/04/024915, MHC-COVID-19-CP, MHC-COVID-19-CP, Version 2.0, NCT04374487 |
Phase 2 Clinical |
Not yet recruiting |
1 |
12 Months |
100 |
Deven Juneja, DNB, Rahul Naithani, MD, DM, Rajesh Saxena, Rajesh Saxena, MBA, Sandeep Budhiraja, MRCP,FACP, Sangeeta Pathak, MBBS,Diploma |
2020-05-07 |
| Stem cell therapy in COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory tract infection, Viral pneumonia |
adipose and placenta-derived mesenchymal stem cell alone, common treatment alone |
|
|
Kermanshah University of Medical Sciences |
|
Iran |
2020-05-09 |
|
IR.KUMS.REC.1399.065, IRCT20200418047121N2 |
Phase 1/Phase 2 Clinical |
Recruiting |
1 |
|
6 |
Farid Najafi, Kamran Mansouri |
2020-05-12 |
| Prevalence of SARS-CoV-2 in Conjunctival Swab Samples Among Patients With Conjunctivitis During the COVID-19 Pandemic |
Conjunctivitis, Coronavirus disease 19 infection, Keratoconjunctivitis, Ocular disease |
conjunctival swab sampling alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Johns Hopkins University |
|
US |
2020-05-31 |
2021-04-30 |
IRB00249598, NCT04374656 |
Phase Not Applicable |
Not yet recruiting |
0 |
11 Months |
50 |
Sezen Karakus, MD |
2020-05-08 |
| Monocytes and NK Cells Activity in Covid-19 Patients |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Università degli Studi dell'Insubria |
|
Italy |
2020-04-27 |
2020-10-31 |
67/2020, NCT04375176 |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
150 |
Andrea Vigezzi, MD, Andreina Baj, MD, Angelo Genoni, Dr, Annarosaria De Vito, PhD, Caterina Franchi, MD, Daniela Dalla Gasperina, Professor, Denisa Baci, PhD, Domenico Iovino, M.D., Domenico Iovino, MD, Elisa Monti, MD, Federica Masci, MD, Francesco Acquati, Professor, Giulio Carcano, Professor, Giuseppe Ietto, M.D., Giuseppe Ietto, MD, Lorenzo Mortara, Professor, Matteo Gallazzi, PhD, Valentina Iori, MD, Walter Ageno, Professor |
2020-05-07 |
| A Study of N-acetylcysteine in Patients With COVID-19 Infection |
Coronavirus disease 19 infection |
N-acetylcysteine alone, supportive care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Memorial Sloan-Kettering Cancer Center |
|
US |
2020-05-01 |
2021-05-31 |
20-168, NCT04374461 |
Phase 2 Clinical |
Recruiting |
0 |
13 Months |
86 |
Jedd Wolchok, MD, PhD, Santosha Vardhana, MD, PhD |
2020-05-11 |
| Inhalable Sodium Bicarbonate: a Possible Adjuvant Treatment of Patients With Novel COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
nebulizer alone, oseltamivir plus sodium bicarbonate |
Exo-alpha sialidase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Mansoura University |
|
Egypt |
2020-04-01 |
2020-06-01 |
NCT04374591, SODIUM BICARBONATE COVID-19 |
Phase 0 Clinical |
No longer recruiting |
1 |
2 Months |
20 |
Mohammed K Elbadrawy, PhD |
2020-05-07 |
| A multicenter, randomized, open, controlled trial for the efficacy and safety of oral kolimycin in the treatment of patients with new coronavirus pneumonia (CoVID-19) |
Coronavirus disease 19 infection |
Basic treatment alone, kolimycin alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Mudanjiang Kang'an Hospital |
|
China |
2020-04-24 |
2021-05-01 |
ChiCTR2000032242 |
Phase 0 Clinical |
Not yet recruiting |
2 |
12 Months |
350 |
Kaijiang Yu |
2020-05-13 |
| COVHECBEHO: COVID-19 Among Healthcare Workers in Belgian Hospitals |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sciensano |
Instituut Voor Tropische Geneeskunde |
Belgium |
2020-04-22 |
2020-09-27 |
COVHECBEHO, NCT04373889, SCIENSANO |
Phase Not Applicable |
Recruiting |
3 |
5 Months |
800 |
Els Duysburgh, MD, MPH, PhD, Laure Mortgat, MD, MPH, Wesley Van Dessel |
2020-05-11 |
| Quality of Life and Physical Performance After Novel Coronavirus Infection (COVID-19) |
Coronavirus disease 19 infection |
education sessions alone, physical exercise alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kantonsspital Winterthur KSW |
|
Switzerland |
2020-03-15 |
2021-08-31 |
2020_00899 / COV19_2020, NCT04375709 |
Phase Not Applicable |
Recruiting |
1 |
17 Months |
60 |
Cornel Sieber, Prof. MD, David Gisi, Giuseppe Mungo, MSc, Ines Unger, MSc Cand., Karrer Urs, PD MD, Markus Hofer, MD, Martina Betschart, PhD, Natalie Ott, MSc Cand., Spencer Rezek, MSc Cand., Swantje Beyer, MD |
2020-05-13 |
| LIFESAVER: Early transfusion of Convalescent Plasma in Elderly COVID-19 Patients to Prevent Disease Progression |
Coronavirus disease 19 infection |
COVID-19 Convalescent Plasma alone, standard therapy alone |
|
Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Policlinico Universitario Agostino Gemelli |
|
Italy |
2020-05-15 |
2021-06-30 |
3205, LIFESAVER, NCT04374526 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
3 |
13 Months |
182 |
Andrea Antinori, Prof., Antonella Cingolani, Jacopo Vecchiet, Prof., Luciana Teofili, Luciana Teofili, Prof., Maurizio Sanguinetti, Raffaele Landolfi, Prof. |
2020-05-08 |
| VADER: Verification of Alternative Do-it-yourself Equipment Respirators for the COVID-19 Personal Protective Equipment (PPE) |
Coronavirus disease 19 infection |
FFP2 alone, Face Fit test alone, Facial mask alone, PortaCount PRO+ 8038 alone, modified full-face snorkelling mask alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Clinique Universitaires Saint-Luc |
|
Belgium |
2020-05-31 |
2020-05-31 |
2020/15AVR/226, NCT04375774, VADER |
Phase Not Applicable |
Recruiting |
1 |
|
10 |
Guillaume Lemaire, MD, Marco Pettinger, MD |
2020-05-11 |
| LESSCOVID: London's Exogenous Surfactant Study for COVID19 |
Coronavirus disease 19 infection |
Bovine Lipid Extract Surfactant alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Lawson Health Research Institute |
London Health Sciences Centre Research Inc |
Canada |
2020-05-01 |
2021-07-01 |
9890, LESSCOVID, NCT04375735 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
14 Months |
20 |
Gordon Barkwell, MSc, Jim Lewis, MD, Tracey Bentall |
2020-05-11 |
| Effect of COVID-19 Pandemic on Pediatric Cancer Care |
Cancer, Coronavirus disease 19 infection |
|
|
|
south egypt cancer institute |
|
Saudi Arabia, Egypt, United Arab Emirates |
2020-05-15 |
2021-05-15 |
COVID-19 AND PEDIATRIC CANCER, NCT04374838 |
Phase Not Applicable |
Not yet recruiting |
3 |
12 Months |
20 |
Mahmoud Motaz Elzembely |
2020-05-07 |
| COVID19-HOPE: Hydroxychloroquine in Combination With Azithromycin or Sirolimus for Treating COVID-19 Patients |
Coronavirus disease 19 infection |
Variable regimens including azithromycin , hydroxychloroquine , sirolimus |
mTOR inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
King Hussein Cancer Center |
|
Jordan |
2020-05-01 |
2020-09-01 |
20 KHCC 74, COVID19-HOPE, NCT04374903 |
Phase 2 Clinical |
Not yet recruiting |
1 |
4 Months |
58 |
Abdelghani Tbakhi, PhD, Amal Al Omari, PhD, Anwar Alnassan, MD, Dalia Al Rimawi, MDS, Feras Hawari, MD, Hikmat Abdel-Razeq, MD, Iyad Ammouri, MD, Iyad Sultan, MD, Mayada Abu Shanap, MD, Mohammed Abufaraj, Prof., Nedal Al-Rawashdeh, MPH, Osama Abu Ata, MD, Rana Damsees, MPH, Rula Najjar, Pharm. D |
2020-05-08 |
| Risk of Venous Thromboembolism in Critically Ill Patients With Severe COVID-19 |
Coronavirus disease 19 infection, Deep vein thrombosis, Lung embolism, Viral pneumonia |
blood test alone, computed tomography angiography alone, duplex ultrasound alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Vall D'Hebron |
|
Spain |
2020-04-01 |
2020-05-01 |
NCT04374617, PR(AG)213/2020 |
Phase Not Applicable |
Completed |
2 |
1 Month |
230 |
Sergi Bellmunt, MD,PhD |
2020-05-08 |
| Study of Oral Ibrutinib Capsules to Assess Respiratory Failure in Adult Participants With CoronaVirus Induced Disease 2019 (COVID-19) and Pulmonary Distress |
Coronavirus disease 19 infection, Respiratory failure |
ibrutinib alone, standard care alone |
Btk tyrosine kinase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
AbbVie Inc |
Janssen Research & Development LLC |
US |
2020-05-06 |
2020-08-27 |
M20-310, NCT04375397 |
Phase 2 Clinical |
Recruiting |
0 |
3 Months |
46 |
ABBVIE CALL CENTER, AbbVie Inc. |
2020-05-08 |
| ACT: Asymptomatic COVID-19 Trial |
Coronavirus disease 19 infection |
Hydroxychloroquine sulfate alone, Hydroxychloroquine sulfate plus azithromycin |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Rutgers University |
|
US |
2020-05-05 |
2021-04-30 |
ACT, NCT04374552, PRO2020000872 |
Phase 2 Clinical |
Not yet recruiting |
0 |
11 Months |
140 |
Helaine Noveck, MPH, Jeffrey L Carson, MD |
2020-05-08 |
| Novel Agents for Treatment of High-risk COVID-19 Positive Patients |
Coronavirus disease 19 infection, Viral pneumonia |
camostat mesylate alone, hydroxychloroquine sulfate alone, Variable regimens including azithromycin , hydroxychloroquine sulfate , ivermectin |
Chloride channel modulator, Serine protease inhibitor, Trypsin inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Kentucky |
|
US |
2020-05-01 |
2021-05-31 |
MCC-20-COVID-01-PMC, NCT04374019 |
Phase 2 Clinical |
Recruiting |
0 |
13 Months |
240 |
Susanne Arnold, M.D., Susanne Arnold, MD |
2020-05-08 |
| Convalescent Plasma for Treatment of COVID-19 Patients With Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
High-Titer Anti-SARS-CoV-2 (COVID 19) Convalescent Plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Virginia |
|
US |
2020-05-05 |
2021-04-05 |
200114, NCT04374565 |
Phase 2 Clinical |
Recruiting |
0 |
11 Months |
29 |
Alex Kadl, MD, Amy Mathers, MD, Archana Thakur, PhD, Chelsea Sheppard, MD, James Gorham, MD, Jeffrey M. Sturek, MD, PhD, Jeffrey Sturek, Jeffrey Sturek, MD, PhD, Karen Ballen, MD, Kristen M Petros De Guex, MA, Lawrence G. Lum, MD, DSc, Melinda Poulter, PhD, Patrick Jackson, MD, Qin Liu, MD, PhD, Scott Heysell, MD, Taison Bell, MD, Tania Thomas, MD, MPH, William B Harrington, MPH |
2020-05-11 |
| COVIDANS Study: Testing for Dysautonomia in Patients Hospitalized for SARS-CoV-2 Infection (COVID-19) |
Autonomic nervous system disease, Coronavirus disease 19 infection |
ECG-Holter alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire de Saint Etienne |
|
France |
2020-04-30 |
2020-10-31 |
2020-A01082-37, 20CH095, COVIDANS Study, NCT04374045 |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
25 |
Béatrice DEYGAS, CRA, David CHARIER, MD, Frédéric ROCHE, MD-PhD, Isabelle COURT-FORTUNE, MD, Jerome MOREL, MD-PhD, Serge MOLLIEX, MD-PhD |
2020-05-07 |
| SARSCoV2 (COVID-19) Convalescent Plasma (CP) Expanded Access Protocol (EAP) |
Coronavirus disease 19 infection |
betacoronavirus (SARSCoV2) convalescent plasma (CP) alone |
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
AdventHealth |
|
US |
|
|
1596191, NCT04374370 |
Phase Not Applicable |
Recruiting |
0 |
|
|
Chris Ensor, PharmD, Eduardo Oliveira, MD |
2020-05-07 |
| Incidence and risk factors for acute kidney injury in COVID-19 |
Coronavirus disease 19 infection, Renal injury |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Klinikum der Albert-Ludwigs Universitaet Freiburg |
|
Germany |
2020-03-01 |
2020-04-30 |
276/20, DRKS00021658 |
Phase Not Applicable |
Completed |
1 |
2 Months |
100 |
Johanna Schneider |
2020-05-07 |
| Efficacy and Safety of Early COVID-19 Convalescent Plasma in Patients Admitted for COVID-19 Infection |
Coronavirus disease 19 infection, Respiratory failure |
Anti-SARS-COV-2 convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Pontificia Universidad Catolica De Chile |
Arturo Lopez Perez Foundation |
Chile |
2020-05-04 |
2021-12-31 |
200415015, NCT04375098 |
Phase 2 Clinical |
Recruiting |
1 |
19 Months |
30 |
Maria Elvira Balcells, MD |
2020-05-07 |
| A trial to evaluate TerraCoV2 for the treatment and prevention of Coronavirus disease 19 infection |
Coronavirus disease 19 infection |
TerraCoV2 vaccine (COVID-19), Noachis Terra alone |
COVID19 Spike glycoprotein modulator |
|
Oragenics Inc |
Noachis Terra Inc |
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-05-07 |
| CovOM: Investigating the microorganisms found in the mouths of SARS-Cov-2 positive patients |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Ferrara |
|
Italy |
2020-04-09 |
2020-10-01 |
COVOM, CovOM, ISRCTN87832712 |
Phase Not Applicable |
Not yet recruiting |
3 |
5 Months |
20 |
Prof Caselli |
2020-05-07 |
| Homoeopathy as adjuvant in management of coronavirus infection |
Coronavirus disease 19 infection |
homoeopathic medicines alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Bajaj Auto Ltd |
|
India |
2020-05-08 |
|
CTRI/2020/04/024925 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
100 |
Dr Abhay S Talwalkar, Dr Anil Khurana, Dr Ayushi Shrikhande, Dr Govindarajan Sankaran |
2020-05-07 |
| COVID Immunity: The COVID Immunity Study |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Translational Genomics Research Institute |
|
US |
|
|
COVID Immunity |
Phase Not Applicable |
Planned |
0 |
|
|
Dr. John Zaia |
2020-05-08 |
| A medical records based retrospective study: leukopenia is more common in asymptomatic patients less than 18 years old with novel coronavirus pneumonia (COVID-19) in convalescence |
Coronavirus disease 19 infection |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Guizhou Provincial Staff Hospital, The Science and Technology Department of Guizhou Province |
|
China |
2020-04-01 |
|
ChiCTR2000032458 |
Phase Not Applicable |
No longer recruiting |
1 |
|
25 |
Wei Zhang |
2020-05-08 |
| A Clinical Trial to Ascertain the Effect of Homoeopathic Medicines in Prevention of Outbreak of Symptoms in Asymptomatic Coronavirus and Suspected Coronavirus Patients |
Coronavirus disease 19 infection |
homoeopathic medicine alone |
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Naiminath Homoeopathic Medical College, Hospital and Research Centre |
|
India |
2020-05-10 |
|
C-2020/05, CTRI/2020/04/024926 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
100 |
Dr Ritu Gupta |
2020-05-07 |
| Diagnostic value of chest CT in outpatient for novel coronavirus pneumonia (COVID-19) compared to RT-PCR |
Coronavirus disease 19 infection, Viral pneumonia |
RT-PCR alone, chest-CT alone |
|
|
The Fifth People's Hospital of Ganzhou |
|
China |
2020-01-01 |
2020-02-29 |
ChiCTR2000032574 |
Phase Not Applicable |
No longer recruiting |
1 |
2 Months |
248 |
Zhang Weiwei |
2020-05-07 |
| A randomized, double-blind, controlled trial for Bu-Fei-Huo-Xue Capsule in the treatment of novel coronavirus pneumonia (COVID-19) convalescence patient with ''Fei-Pi-Qi-Xu zhen'' |
Coronavirus disease 19 infection, Viral pneumonia |
Bufei Huoxue Capsule alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
State Key Laboratory Of Respiratory Diseases, The Fifth Affiliated Hospital of Guangzhou Medical University |
|
China |
2020-05-02 |
2021-05-01 |
ChiCTR2000032573 |
Phase 0 Clinical |
Not yet recruiting |
5 |
12 Months |
120 |
Jian Wang, Nanshan Zhong |
2020-05-07 |
| Placental Mesenchymal Stem Cell Therapy for Acute Respiratory Distress Syndrome in Coronavirus Infection: A Phase I/II Clinical Trial |
Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia |
placental mesenchymal stem cell therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
National Institute for Medical Research Developement, Oghaf Organization and charity, Opal Parsian Company |
|
Iran |
2020-03-20 |
|
IR.TUMS.VCR.REC.1399.009, IRCT20200413047063N1 |
Phase 1/Phase 2 Clinical |
Recruiting |
2 |
|
20 |
Masoud Soleimani, Mohamad Azimi, Mohammad Alian Nejad, Mohammad Mokhber, Mohammad Reza Hashemian, Mohammad Vasei, Reza Malekzadeh, Sayed Mahdi Khamooshi |
2020-05-07 |
| Ozone Autohemotherapy in COVID-19 |
Coronavirus disease 19 infection |
conventional therapy alone, major autohemotherapy alone, ozone alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Tabriz University of Medical Sciences |
|
Iran |
2020-04-25 |
|
IR.TBZMED.REC.1399.022, IRCT20190618043923N4 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
|
20 |
Dawood Aghamohammadi, Mohammad Samiei |
2020-05-07 |
| PIONEER: A Randomized, Controlled Trial of Early Intervention in COVID-19: Favipiravir Versus Hydroxycholorquine and Azithromycin and Zinc versus Standard Care |
Coronavirus disease 19 infection, Influenza virus infection |
favipiravir alone, standard clinical care alone, Variable regimens including Plaquenil , azithromycin , zinc sulfate |
RNA polymerase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Chelsea & Westminster NHS Trust |
FUJIFILM Toyama Chemical Co Ltd, Imperial College London, Neat Id Foundation, Universitaire Ziekenhuizen Leuven |
UK |
2020-05-01 |
2021-03-31 |
2020-001449-38, CW002, NCT04373733, PIONEER |
Phase 3 Clinical |
Not yet recruiting |
2 |
11 Months |
450 |
Bobby Mann, Pallav Shah, Research Delivery Operations Manager |
2020-05-07 |
| A Clinical Trial to study the effectiveness of Homoeopathy as an additional mode of treatment in combating Corona Virus infection |
Coronavirus disease 19 infection |
Homoeopathy (Arsenic Album, Bryonia Alba, Gelsemium, Antimonium Tartaricum, Crotalus Horridus) alone |
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Central Council for Research in Homeopathy, Naiminath Homoeopathic Medical College, Hospital and Research Centre |
|
India |
2020-05-05 |
|
C-2020/01, CTRI/2020/04/024905 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
100 |
Dr Shaurabh Kumar |
2020-05-07 |
| PROTEGO: Prospective, Observational, Cohort Trial Evaluating Correlation of Clinical Findings, Symptoms And Disease Development Of German In- Or Outpatients Infected With SARS-CoV-2 - A CHIR-Net Student-Initiated German Medical Audit trial COVID-19 study (CHIR-Net SIGMA study group) |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Heidelberg |
|
Germany |
2020-05-07 |
|
DRKS00021226, PROTEGO, S-215/2020, U1111-1250-1571 |
Phase Not Applicable |
Not yet recruiting |
2 |
|
500 |
André Mihaljevic |
2020-05-07 |
| The effect of Intravenous immunoglobulin on COVID-19 infection |
Coronavirus disease 19 infection |
Intratect alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Gonabad University of Medical Sciences |
|
Iran |
2020-03-10 |
|
IR.GMU.REC.1399.009, IRCT20200418047116N1 |
Phase 2 Clinical |
Recruiting |
1 |
|
20 |
Dr. Shahla Khosravan, Najme Davoodian, Negar Shafaei Bajestani |
2020-05-06 |
| ATTACC: Antithrombotic Therapy to Ameliorate Complications of COVID-19 |
Bleeding, Coronavirus disease 19 infection, Ischemic stroke, Myocardial infarction, Thrombocytopenia |
dalteparin sodium alone, enoxaparin sodium alone, tinzaparin sodium alone, unfractionated heparin alone |
Antithrombin III, Factor IIa antagonist, Factor Xa antagonist, Low molecular weight heparin |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Manitoba |
Hamilton Health Sciences Corp, Hopital Montfort, The University Health Network |
Canada |
2020-05-31 |
2021-01-31 |
ATTACC, ATTACC, NCT04372589, OZM-113 |
Phase 2 Clinical |
Not yet recruiting |
3 |
8 Months |
3000 |
Ewan Goligher, MD, Jean-Philippe Galanaud, MD, Marc Carrier, MD, Patrick Lawler, Ryan Zarychanski, MD |
2020-05-13 |
| C-reactive Protein Levels Among Individuals With COVID-19 |
Coronavirus disease 19 infection |
C-reactive protein test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Frederiksberg University Hospital |
|
Denmark |
2020-05-04 |
2020-11-30 |
APPI2-CV-2020-02, NCT04373798 |
Phase Not Applicable |
Not yet recruiting |
1 |
6 Months |
3000 |
Henning Bliddal, DMSc |
2020-05-06 |
| An international, investigator-initiated clinical trial to evaluate the efficacy of Lambda in the treatment of patients with COVID-19 infection |
Coronavirus disease 19 infection |
peginterferon lambda-1a, Eiger BioPharmaceuticals alone |
Interferon receptor modulator, Interleukin-29 ligand |
|
University of Toronto |
Eiger BioPharmaceuticals Inc |
Canada |
2020-04-30 |
|
|
Phase Not Applicable |
Recruiting |
1 |
|
|
|
2020-05-05 |
| An international, investigator-initiated clinical trial to evaluate the efficacy of Lambda in the treatment of patients with COVID-19 infection |
Coronavirus disease 19 infection |
peginterferon lambda-1a, Eiger BioPharmaceuticals alone |
Interferon receptor modulator, Interleukin-29 ligand |
|
Mount Sinai Hospital |
Eiger BioPharmaceuticals Inc |
US |
2020-04-30 |
|
|
Phase Not Applicable |
Recruiting |
0 |
|
|
|
2020-05-05 |
| COVID-APE: Incidence of Acute Pulmonary Embolism in COVID-19 Patients on CT Angiography and Relationship to D-dimer Levels |
Coronavirus disease 19 infection, Lung embolism |
chest CT angiography alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hopitaux Universitaires de Strasbourg |
|
France |
2020-03-03 |
2020-05-01 |
7840, COVID-APE, NCT04373486 |
Phase Not Applicable |
Recruiting |
1 |
1 Month |
160 |
Aissam LABANI, MD, Catherine ROY, MD, Coralie PAUZET, MD, Françis SCHNEIDER, MD, PhD, François SEVERAC, MD, Ian LEONARD-LORANT, MD, Julie HELMS, MD, PhD, Mickaël OHANA, MD, PhD, Olivier COLLANGE, MD, PhD, Pascal BILBAULT, MD, PhD, Pierre LEYENDECKER, MD, Saïd CHAYER, PhD, HDR, Sébastien MOLIERE, MD, Xavier DELABRANCHE, MD, PhD |
2020-05-06 |
| An international, investigator-initiated clinical trial to evaluate the efficacy of Lambda in the treatment of patients with COVID-19 infection |
Coronavirus disease 19 infection |
peginterferon lambda-1a, Eiger BioPharmaceuticals alone |
Interferon receptor modulator, Interleukin-29 ligand |
|
Soroka University Medical Center |
Eiger BioPharmaceuticals Inc |
Israel |
2020-04-30 |
|
|
Phase Not Applicable |
Recruiting |
1 |
|
|
|
2020-05-05 |
| COVID-SHIELD: COVID-19 prophylaxis with hydroxychloroquine in Front-line Health and Allied-Health Care Workers |
Coronavirus disease 19 infection |
hdroxychloroquine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Walter and Eliza Hall Institute of Medical Research |
Australian Government |
Australia |
2020-04-28 |
|
ACTRN12620000501943p, COVID-SHIELD, U1111-1250-4307 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
15 |
|
2250 |
Arunee Wilson, Ms Liz Williams, Prof Marc Pellegrini |
2020-05-06 |
| VM Spacer plus MDI use in Outpatient ED - COVID-19 Pandemic |
Coronavirus disease 19 infection, Respiratory disorder |
Venturi Mask alone |
|
|
Hospital Kuala Lumpur |
|
Malaysia |
2020-05-01 |
2021-04-30 |
54673, NMRR-20-840-54673 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
103 |
Dr. Jacelyn Ong Jia Whey, KOH HOCK PENG |
2020-05-06 |
| Health Outcome Rheum Pt on SoC Dur Covid-19 |
Coronavirus disease 19 infection |
standard of care alone |
|
|
Selayang Hospital |
|
Malaysia |
2020-05-04 |
2020-05-28 |
54731, NMRR-20-839-54731 |
Phase Not Applicable |
Status not specified |
1 |
|
|
Dr Lim Shiau Li |
2020-05-05 |
| Survey of WHOQoL-Bref Scores Among Persons with Chronic Illness and Public During COVID-19 Pandemic in Malaysia |
Coronavirus disease 19 infection |
|
|
|
HOSPITAL TENGKU AMPUAN RAHIMAH KLANG |
|
Malaysia |
2020-04-29 |
2020-12-31 |
54818, NMRR-20-838-54818 |
Phase Not Applicable |
Not yet recruiting |
1 |
8 Months |
|
Dr. Jacelyn Ong Jia Whey, Dr. Muralitharan Perumal |
2020-05-05 |
| McMonty: A reusable personalised ventilation hood: a phase I safety study of a new device (McMonty) in patients with suspected or confirmed COVID-19 |
Coronavirus disease 19 infection |
McMonty hood device alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Western Health |
Sunshine Hospital, University of Melbourne |
Australia |
2020-05-01 |
|
ACTRN12620000500954p, McMonty, U1111-1250-6657 |
Phase 1 Clinical |
Not yet recruiting |
2 |
|
20 |
Dr Forbes McGain |
2020-05-06 |
| A study to assess the effectiveness of Ayurvedic formulation in addition to standard of care in COVID-19 positive patients in a tertiary hospital |
Coronavirus disease 19 infection |
Tinospora cordifolia stem kashaya alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Medanta The Medicity, Ministry of Ayush |
Central Council for Research in Ayurvedic Sciences, Council of Scientific and Industrial Research (India) |
India |
2020-04-28 |
|
CTRI/2020/04/024882 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
60 |
DrSushila Kataria, Mr.Kuldeep K Chauhan |
2020-05-06 |
| The CERA Study: The COVID-19 Emergency Response Assessment Study: a survey of the psychological health of frontline doctors in the UK and Ireland during the coronavirus pandemic |
Coronavirus disease 19 infection |
|
|
|
North Bristol NHS Trust |
Royal College of Emergency Medicine |
Ireland, UK |
2020-03-12 |
2020-10-01 |
ISRCTN10666798, The CERA Study, V5.0, IRAS 281944 |
Phase Not Applicable |
Recruiting |
2 |
6 Months |
7000 |
Dr Tom Roberts |
2020-05-06 |
| Treatment of COVID19 : A randomized controlled trial |
Coronavirus disease 19 infection, Viral pneumonia |
hydroxychloroquine alone, azithromycin plus hydroxychloroquine |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ministry of Defence |
|
India |
2020-05-11 |
|
CTRI/2020/04/024904 |
Phase 3 Clinical |
Not yet recruiting |
6 |
|
300 |
AirCmde V K Sashindran, Ajay Kumar, Col Anurag Khera, Col Sanjeevan Sharma, Dheeraj Kumar, Kuldeep Ashta, Rajneesh Thakur, Snehangsh Dash |
2020-05-07 |
| HelloBetter Corona: Naturalistic evaluation of an Internet-based psychological training program for mental strain associated with the coronavirus / COVID-19 pandemic |
Coronavirus disease 19 infection, Psychiatric disorder |
HelloBetter Corona online training alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Friedrich-Alexander-Universitaet Erlangen-Nuernberg |
|
Germany |
2020-05-06 |
|
172_20 B, DRKS00021588, HelloBetter Corona |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1000 |
Mathias Harrer |
2020-05-05 |
| SROCL: Stroke Rehabilitation Outcome During COVID-19 Lockdown |
Coronavirus disease 19 infection, Hemorrhagic stroke, Ischemic stroke |
physical activity engagement alone, rehabilitation therapy alone, upper limb usage alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Zurich |
|
Switzerland |
2020-04-16 |
2021-04-30 |
BASEC-NR. 2020-00761, NCT04373109, SROCL |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
70 |
Andreas R Luft, Prof, Janne M Veerbeek, PhD, Jeremia Held, Jeremia PO Held, PhD |
2020-05-07 |
| Characteristics of seriously ill COVID-19 patients admitted to a tertiary care center |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
All India Institute of Medical Sciences |
|
India |
2020-05-08 |
|
CTRI/2020/04/024914 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
60 |
Dr Sulagna Bhattacharjee |
2020-05-11 |
| Impact of Quarantine on Quality of Life Among Persons Screened for COVID-19 in Malaysia |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
HOSPITAL TENGKU AMPUAN RAHIMAH KLANG |
|
Malaysia |
2020-04-30 |
2020-07-29 |
54817, NMRR-20-837-54817 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
|
Dr Yap Soong Yiing, Dr. Muralitharan Perumal |
2020-05-11 |
| Clinical research on safety and efficacy of ZingiVir-H as an add on therapy in COVID-19 patients |
Coronavirus disease 19 infection |
ZingiVir-H alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Pankajakasthuri Ayurveda Medical College and Post Graduate Center |
|
India |
2020-04-29 |
|
CTRI/2020/04/024883 |
Phase 4 Clinical |
Recruiting |
1 |
|
112 |
Dr Shan Sasidharan, DrJHareendran Nair |
2020-05-05 |
| NPATCM |
Coronavirus disease 19 infection |
Decoction of Traditional Chinese Medicines therapy alone |
|
|
National Institutes of Health Malaysia |
|
Malaysia |
2020-04-28 |
2022-04-01 |
LFF0015 54738, NMRR-20-833-54738 |
Phase Not Applicable |
Status not specified |
1 |
23 Months |
|
Dr lem fui fui |
2020-05-12 |
| PRIEST: Evaluation of COVID-19 assessment in emergency departments and ambulance services |
Coronavirus disease 19 infection, Respiratory tract infection |
Emergency triage alone |
|
|
Sheffield Teaching Hospitals NHS Foundation Trust |
NIHR Evaluation, Trials and Studies Coordinating Centre (NETSCC) |
UK |
2012-10-01 |
2020-07-31 |
CPMS 12725, IRAS 101138, ISRCTN28342533, PRIEST |
Phase Not Applicable |
Recruiting |
64 |
94 Months |
|
Prof Goodacre |
2020-05-05 |
| GPWTMCVD19 |
Coronavirus disease 19 infection |
personal protective equipment alone |
|
|
HOSPITAL SERI MANJUNG |
|
Malaysia |
2020-05-01 |
2020-12-31 |
54819, NMRR-20-832-54819 |
Phase Not Applicable |
Recruiting |
1 |
8 Months |
|
Gobi Hariyanayagam a/l Gunasekaran |
2020-05-11 |
| Clinical and immunological predictors of SARS-CoV-2 infection and COVID-19 diseases in patients with renal diseases and healthy persons |
Coronavirus disease 19 infection, Renal disease |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Nierenzentrum Heidelberg |
Nierenzentrum e.V. |
Germany |
2020-04-06 |
|
DRKS00021297, S-224/2020 |
Phase Not Applicable |
Recruiting |
1 |
|
100 |
Claudia Sommerer |
2020-05-05 |
| Antiviral Therapy and Baricitinib for the Treatment of Patients With Moderate or Severe COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
Variable regimens including baricitinib , hydroxychloroquine , lopinavir + ritonavir , remdesivir |
Coronavirus non structural protein 8 modulator, HIV protease inhibitor, Jak1 tyrosine kinase inhibitor, Jak2 tyrosine kinase inhibitor, RNA polymerase modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Southern California |
National Cancer Institute |
US |
2020-05-18 |
2022-04-24 |
0S-20-3, NCI-2020-02685, NCT04373044, P30CA014089 |
Phase 2 Clinical |
Not yet recruiting |
0 |
23 Months |
59 |
Heinz-Josef Lenz, MD, Tali Homsey, BA |
2020-05-13 |
| The Prophylactic Effect Of Hydroxychloroquine On Novel Corona Virus |
Coronavirus disease 19 infection |
hydroxychloroquine, Tehran Darou, Iran alone, routine care alone |
|
|
Arak University of Medical Sciences and Health Services |
|
Iran |
2020-04-13 |
|
IR.ARAKMU.REC.1398.345, IRCT20151222025660N2 |
Phase 3 Clinical |
Recruiting |
2 |
|
140 |
Dr Alirza Kamali, Dr. Ramin Parvizrad, Dr.Ramin Parvizrad |
2020-05-06 |
| Survive and Thrive: exploring the wellbeing of doctors in a post-COVID-19 era |
Anxiety disorder, Coronavirus disease 19 infection, Depression |
|
|
|
University Of Southampton |
Health Education England |
UK |
2020-01-21 |
2021-12-31 |
55747, ISRCTN20867558 |
Phase Not Applicable |
Recruiting |
1 |
23 Months |
350 |
Dr Simons |
2020-05-06 |
| Epidemiology and Outcome of Ventilator-associated Pneumonia Among Critically Ill COVID-19 Patients |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Semmelweis University |
|
Hungary |
2020-04-16 |
2020-08-31 |
57/2020., NCT04372576 |
Phase Not Applicable |
Recruiting |
1 |
4 Months |
30 |
Bence Mogyoródi, MD, Zsolt Iványi |
2020-05-06 |
| PredictCovidT: Blood Biomarkers as Predictors of COVID-19 Disease Progression in Recently Infected Kidney Transplant Patients |
Coronavirus disease 19 infection |
blood sample alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire De Nice |
|
France |
2020-04-22 |
2020-10-22 |
20-PP-09, NCT04369456, PredictCovidT |
Phase Not Applicable |
Recruiting |
7 |
6 Months |
115 |
Alexandre HERTIG, Antoine SICARD, Barbara SEITZ-POLSKI, Christophe MARIAT, Dany ANGLICHEAU, Elisa DEMONCHY, Jean DELLAMONICA, Moglie Le Quintrec, Olivier THAUNAT, Renaud SNANOUDJ, Valerie MOAL, alexandre HERTIG, christophe MARIAT, cynthia CAILLON, sophie Caillard Ohlmann, valerie MOAL |
2020-05-06 |
| INVICTUS: Weaning From Mechanical Ventilation for ARDS CovId-19 Patients Guided by Combined Thoracic Ultrasound |
Coronavirus disease 19 infection, Respiratory distress syndrome |
combined thoracic ultrasound-based mechanical ventilation weaning alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire de Toulouse |
|
France |
2020-04-22 |
2020-09-22 |
2020-A00916-33, INVICTUS, NCT04372680, RC31/20/0138 |
Phase Not Applicable |
Recruiting |
2 |
5 Months |
200 |
AUDREY BELLOC, Beatrice RIU-POULENC, PH, Béatrice RIU-POULENC, NADERA AINAOUI, PHD, Paul BOURZEIX, Philippe VIGNON, PU PH, Stein SILVA, PU PH |
2020-05-06 |
| Efficacy of solnatide to treat pulmonary permeability oedema in SARS-Cov-2 positive patients with moderate-to-severe ARDS |
Coronavirus disease 19 infection, Pulmonary edema, Respiratory distress syndrome |
solnatide (liquid aerosol inhalation, pulmonary edema), Apeptico/ Mediolanum alone |
Sodium channel stimulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Medical University of Vienna |
Apeptico Forschung und Entwicklung GmbH |
Austria |
2020-04-11 |
|
2020-001244-26, COV-2-SOLNATIDE-20 |
Phase 2 Clinical |
Recruiting |
1 |
|
40 |
Markus Zeitlinger |
2020-05-07 |
| Effect of Atorvastatin in Treatment of COVID-19 Infection |
Coronavirus disease 19 infection |
atorvastatin alone, standard treatment alone |
HMG CoA reductase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Islamic Azad University |
|
Iran |
2020-04-13 |
|
IR.IAU.PS.REC.1399.002, IRCT20200413047062N1 |
Phase 3 Clinical |
No longer recruiting |
1 |
|
76 |
Farshad Hashemian, Hamidreza Moezi, Keyhan Mohammadi, Maysa Ghayyem |
2020-05-14 |
| Understanding Immunity to SARS-CoV-2, the Coronavirus Causing COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Stanford University |
National Institute of Allergy and Infectious Diseases |
US |
2020-04-08 |
2022-04-30 |
2U19AI057229, IRB-55689, NCT04373148 |
Phase Not Applicable |
Recruiting |
0 |
24 Months |
1000 |
Hena Din, Kari Nadeau, MD, PhD |
2020-05-06 |
| Analysis of clinical features of novel coronavirus pneumonia (COVID-19): a medical records based study |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Xiangya Hospital Of Central South University |
|
China |
2020-03-23 |
2021-03-23 |
ChiCTR2000032476 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
500 |
Pinhua Pan |
2020-05-06 |
| A medical records based retrospective study for effect of applying individualized Chinese herbal medicine in treatment of patients with novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Chinese herbal medicine alone |
|
|
The Affiliated Hospital of Chengdu University of Traditional Chinese Medicine |
Science & Technology Department of Sichuan Province |
China |
2020-05-06 |
2020-07-31 |
ChiCTR2000032461, ChiMCTR2000003266 |
Phase Not Applicable |
Not yet recruiting |
3 |
2 Months |
500 |
Chunguang Xie, Huizhen Chen |
2020-05-06 |
| Assessment of effect of levamisole on pneumonia caused by COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
levamisole alone, symptomatic therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Shiraz University of Medical Sciences |
|
Iran |
2020-05-04 |
|
IR.SUMS.REC.1399.178, IRCT20131215015805N2 |
Phase 4 Clinical |
Recruiting |
1 |
|
50 |
Dr Mohsen Moghaddami, Dr Payam Peymani, Dr mohsen moghadami, Kamran Bagheri Lankarani |
2020-05-06 |
| MeHeS-STAFF |
Coronavirus disease 19 infection |
|
|
|
Hospital Tunku Azizah |
|
Malaysia |
2020-05-01 |
2020-10-31 |
54721, NMRR-20-852-54721 |
Phase Not Applicable |
Not yet recruiting |
1 |
6 Months |
|
Dr LUI SZE CHIANG |
2020-05-06 |
| SOAP: School opening in Norway during the COVID-19 pandemic |
Coronavirus disease 19 infection |
school opening program alone |
|
|
Norwegian Institute of Public Health |
|
Norway |
2020-03-18 |
2020-09-30 |
ISRCTN44152751, SOAP |
Phase Not Applicable |
Not yet recruiting |
1 |
6 Months |
125 |
Prof Atle Fretheim |
2020-05-06 |
| ACICOVID: Cardiac Arrest Incidence and Outcome Among Patients With COVID-19 in French ICUs |
Cardiac arrest, Coronavirus disease 19 infection, Viral pneumonia |
cardiopulmonary resuscitation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer |
|
France |
2020-05-31 |
2020-12-31 |
2020-CHITS-004, ACICOVID, NCT04373759 |
Phase Not Applicable |
Not yet recruiting |
39 |
7 Months |
100 |
Alain Gaffinel, Arnaud Galbois, Arnaud Galbois, MD, Asmaa JOBIC, Benjamin Sztrymf, Benjamin Sztrymf, MD, Camille Foucault, Camille Foucault, MD, Cedric Bruel, Cedric Bruel, MD, Cedric Daubin, Cedric Daubin, MD, Charles Damoisel, MD, Christophe Vinsonneau, Christophe Vinsonneau, MD, Clement Suply, Coralie Gernez, Damien Roux, MD, Damien Vimpere, David Schnell, David Schnell, MD, Didier Thevenin, Didier Thevenin, MD, Dorothee Carpentier, Dorothee Carpentier, MD, Elena Skripkina, Elena Skripkina, MD, Elodie Bouvier, Gabriel Lejour, Gaetan Plantefeve, Gaetan Plantefeve, MD, Guillaume Geri, Guillaume Geri, MD, Jean-Philippe Suppini, Jean-Pierre Quenot, Jean-Pierre Quenot, MD, Jennifer Brunet, Jobic Asmaa, Jonathan Chelly, Jonathan Chelly, MD, Julie Noublanche, Julien Fournier, Julio Badie, Karim Chaoui, MD, Laurent Guérin, Lionel Lamhaut, Ly Van Vong, Ly Van Vong, MD, Marie-Anne Mélone, MD, Marine Paul, Marine Paul, MD, Marjorie Fleury, Maxime Leloup, Maxime Leloup, MD, Michel Kaidomar, Mihaela Mihaila, Mohamed Bouguettaya, Natacha Kapandji, Natacha Kapandji, MD, Nicolas Deye, Nicolas Deye, MD, Nicolas Pichon, Nicolas Pichon, MD, Nicolas Terzi, Nicolas Terzi, MD, Riad Chelha, MD, Richard Descamps, MD, Romain Persichini, Romain Persichini, MD, Romaric Larcher, Saad Nseir, Saad Nseir, MD, Sandie Mazerand, Santiago Freita Ramos, Santiago Freita Ramos, MD, Santiago Picos, Sebastien Ehrminger, MD, Sebastien Jochmans, Sebastien Jochmans, MD, Tai Pham, Thomas Hullin, Thomas Hullin, MD, Toufik Kamel, Toufik Kamel, MD, Vivien Hong Tuan Ha, Vivien Hong Tuan Ha, MD |
2020-05-13 |
| Screening of Cancer Patients to Assess Impact of COVID-19 |
Coronavirus disease 19 infection |
nasopharyngeal (NP) swab alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The University Health Network |
|
Canada |
2020-05-04 |
2020-12-04 |
CAPCR 20-5337, NCT04373005, U-DEPLOY: RESPONSE |
Phase Not Applicable |
Not yet recruiting |
1 |
7 Months |
1000 |
Stephanie Lheureux, M.D. |
2020-05-06 |
| HARMONICOV: Human Ab Response and immunomonitoring of COVID-19 Patients |
Coronavirus disease 19 infection, Respiratory distress syndrome |
blood sampling alone, immunomonitoring alone, saliva collection alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Rennes University Hospital |
|
France |
2020-05-15 |
2020-11-15 |
2020-A01100-39, 35RC20_9795_HARMONICOV, HARMONICOV, NCT04373200 |
Phase Not Applicable |
Not yet recruiting |
1 |
6 Months |
75 |
Alexandre MANSOUR, MD, Florian REIZINE, MD, Isabelle GOUIN, MD, Jean-Marc TADIE, MD, PhD, Karin TARTE, MD, PhD, Mathieu LESOUHAITIER, MD, Michel COGNE, MD, PhD, Mikaël ROUSSEL, MD |
2020-05-12 |
| COVENTRY: One-Year Quality of Life and Functional Prognosis of COVID-19 Patients in Post-ICU Setting |
Coronavirus disease 19 infection |
lung ultrasound alone, muscle ultrasound alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Groupe Hospitalier Paris Saint-Joseph |
Hôpital Forcilles |
France |
2020-04-16 |
2021-09-16 |
COVENTRY, COVENTRY, NCT04373811 |
Phase Not Applicable |
Recruiting |
1 |
17 Months |
50 |
Andreia LOPES, PT, Aymeric LE NEINDRE, PT, PhD, Carlos DIAZ, PT, MSc, Gérald CHOUKROUN, MD, Hélène BEAUSSIER, PharmD, PhD, Joséphine COTTIAS, PT, Nesrine BEN NASR, PharmD, PhD, Pascal MEYER, MD |
2020-05-06 |
| BRACE-CORONA: Angiotensin Receptor Blockers and Angiotensin-converting Enzyme Inhibitors and Adverse Outcomes in Patients With COVID19 |
Coronavirus disease 19 infection |
Suspension of Angiotensin Receptor Blockers and Angiotensin-converting Enzymes alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Instituto D'Or de Pesquisa |
Brazilian Clinical Research Institute |
Brazil |
2020-04-06 |
2020-12-01 |
BRACE-CORONA, NCT04364893, PRJ_2003 |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
500 |
Renato D. Lopes, MD, PhD |
2020-05-11 |
| Study for using sulfate in the prevention and control of novel coronavirus pneumonia (COVID-19) in high and low prevalence communities |
Coronavirus disease 19 infection, Viral pneumonia |
hydroxychloroquine sulfate alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Shanghai Public Health Clinical Center |
|
China |
2020-03-01 |
2020-09-30 |
ChiCTR2000032487 |
Phase 4 Clinical |
Not yet recruiting |
1 |
7 Months |
2000 |
Lu Xia, Shuihua Lu |
2020-05-06 |
| CRC-COVID: COVID-19 Infection: Exploration of Respiratory Control Center Abnormalities |
Coronavirus disease 19 infection |
14.3 and 12.7% FIO2, hypercapnia 7% CO2, inspiratory mechanical constraint alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assistance Publique Hopitaux de Paris |
|
|
2020-04-27 |
2021-11-27 |
APHP200476, CRC-COVID, NCT04363749 |
Phase Not Applicable |
Not yet recruiting |
0 |
19 Months |
30 |
Thomas Similowski, MD, PhD |
2020-05-08 |
| Comparison of three methods of treatment in patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with and without coronavirus positive test (COVID-19) |
Coronavirus disease 19 infection, Vitamin C deficiency, Vitamin D deficiency |
routine treatment alone, vitamin C supplement alone, vitamin D supplement alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sabzevar University of Medical Sciences |
|
Iran |
2020-04-20 |
|
IR.MEDSAB.REC.1399.015, IRCT20140305016852N4 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
|
30 |
Ebrahim Shirzade, Fereshteh Ghorat, Somayyeh Nayyeri |
2020-05-06 |
| COVIDOP-DVT: Incidence of Deep Vein Thrombosis at Doppler Echo in Covid-19 Patients With SARS-Cov-2 Pneumopathy Hospitalized in ICU |
Coronavirus disease 19 infection, Deep vein thrombosis, Viral pneumonia |
Doppler Echo alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Versailles University Hospital |
|
France |
2020-04-27 |
2020-10-30 |
COVIDOP-DVT, NCT04363528, P20/08 |
Phase Not Applicable |
Not yet recruiting |
1 |
6 Months |
50 |
Aurelien Maurizot |
2020-05-12 |
| KAPFM |
Coronavirus disease 19 infection |
respiratory protective device alone |
|
|
HOSPITAL SERI MANJUNG |
|
Malaysia |
2020-05-04 |
2020-12-01 |
54775, NMRR-20-850-54775 |
Phase Not Applicable |
Status not specified |
1 |
6 Months |
|
Gobi Hariyanayagam a/l Gunasekaran |
2020-05-06 |
| Clinical study on Dabur Chyawanprash as a preventive remedy in pandemic of Covid-19 |
Coronavirus disease 19 infection |
Chyawanprash alone |
|
Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Dabur India Ltd |
|
India |
2020-05-15 |
|
CTRI/2020/05/024981, DCP-CVD-19/2020/01 |
Phase Not Applicable |
Not yet recruiting |
5 |
|
600 |
Dr Arun Gupta, Dr Pawankumar Godatwar, Dr Pranita Deshmukh, Dr Raman Ghungralekar, Dr Sanjay Tamoli, Dr Shailesh Deshpande, Dr Vaishali Deshpande |
2020-05-07 |
| COVI-DOSE: Weight-Adjusted versus Fixed Low-Doses of Low Molecular Weight Heparin For Venous Thromboembolism Prevention in COVID-19 |
Coronavirus disease 19 infection, Thromboembolism, Viral pneumonia |
Variable regimens including dalteparin sodium , enoxaparin sodium , nadroparin calcium , tinzaparin sodium |
Antithrombin III, Factor IIa antagonist, Factor Xa antagonist, Low molecular weight heparin |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Central Hospital, Nancy, France |
Ministry of Health, France |
France |
2020-05-31 |
2020-10-31 |
2020-001709-21, COVI-DOSE, NCT04373707 |
Phase 4 Clinical |
Not yet recruiting |
14 |
5 Months |
602 |
Alessandra Bura-Rivière, Amer Hamadé, Béatrice Terriat, Dominique Stephan, El Mehdi Siaghy, Francis Couturaud, Gabrielle Sarlon-Bartoli, Isabelle Quéré, Julien Bertrand, Nicolas Meneveau, Olivier Sanchez, Patricia Costa, Patrick Mismetti, Saïda Khaled-Jousselin, Res Proj Man, Simon Soudet, Stéphane Zuily, Stéphane Zuily, MD, PhD, Wael Younès, Yohann Bernard, Res Proj Man |
2020-05-06 |
| Homoeopathy as adjuvant in management of Covid-19 infection |
Coronavirus disease 19 infection, Viral pneumonia |
Homoeopathic medicines alone, standard treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Naiminath Homoeopathic Medical College, Hospital and Research Centre |
|
India |
2020-05-10 |
|
CTRI/2020/05/024969 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
100 |
Dr Anil Khurana, Dr Debadatta Nayak, Prof Dr Pradeep Kumar Gupta |
2020-05-07 |
| PROVID-19: Impact of Prone Position in Patients Under Spontaneous Breathing on Intubation or Non-invasive Ventilation or Death Incidence During COVID-19 Acute Respiratory Distress |
Coronavirus disease 19 infection |
conventional positioning alone, prone position alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Régional d'Orléans |
|
France |
2020-05-31 |
2022-05-31 |
CHRO-2020-09, NCT04363463, PROVID-19 |
Phase Not Applicable |
Not yet recruiting |
14 |
24 Months |
400 |
Amanda LOPES, Dr, Aurélie DESPUJOLS, Aymeric SEVE, Dr, Elodie POUGOUE TOUKO, Elsa NYAMANKOLLY, Elsa NYAMANKOLLY, Dr, François MAILLOT, Pr, Jean-François GAUTIER, Pr, Laurent PLANTIER, Pr, Louis BERNARD, Pr, Léa COLOMBAIN, Dr, MARINE MORIER, Mai-Anh NAY, Dr, Marine MORIER, Dr, Nicolas BIZIEN, Dr, Pierre SELLIER, Pr, Sylvie DRUELLE, Sylvie DRUELLE, Dr, Xavier POUGET-ABADIE, Xavier POUGET-ABADIE, Dr |
2020-05-12 |
| COVID'HEMOS: Study of the Vascular Compartment and Hypercoagulability During Coronavirus Infection COVID-19 |
Coronavirus disease 19 infection |
blood sampling alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Boisguillaume |
|
France |
2020-04-09 |
2020-07-31 |
2020/0104/OB, COVID'HEMOS, NCT04367662 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
100 |
Francois CARON, Pr, Julien BLOT, Manuel ETIENNE, Pr, Paul BILLOIR, Pharmacist, Paul BILLOIR, pharmacist, Véronique LE CAM, MD |
2020-05-06 |
| COVID-19 social study: the effects of quarantine on mental health |
Coronavirus disease 19 infection, Psychiatric disorder |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University College London |
Nuffield Foundation |
UK |
2020-03-23 |
2020-12-31 |
12467/005, ISRCTN97041334 |
Phase Not Applicable |
Recruiting |
1 |
9 Months |
1000000 |
Ms Vas James |
2020-05-06 |
| Developing and validating of clinical prediction model for novel coronavirus pneumonia (COVID-19) patients progressing to critical type, acute respiratory distress syndrome and death: a medical records based study |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tongji Medical College |
|
China |
2020-05-01 |
2021-04-30 |
ChiCTR2000032527 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
8500 |
Shusheng Li, Yi Bian |
2020-05-06 |
| Enhanced Hood PPE to Minimize COVID-19 Transmission to Front-line Health Care Workers |
Coronavirus disease 19 infection |
modified IPAC-UHN PPE alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
The University Health Network |
|
Canada |
2020-05-07 |
2020-08-31 |
20-5448, NCT04373096 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
42 |
Anahi Perlas, MD,FRCPC, Mehdi Soheili, Rongyu Jin |
2020-05-06 |
| MUM: Global Mental Health of Urban Mothers |
Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder |
Web-based psychosocial peer-to-peer support alone |
|
Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Karolinska Institutet |
Swiss National Science Foundation |
Sweden, Hong Kong, China |
2020-06-30 |
2023-06-30 |
MUM, NCT04363177, P2SKP3_187728 |
Phase Not Applicable |
Not yet recruiting |
3 |
36 Months |
300 |
Ewa Andersson, PhD, Hsuan-Ying Huang, PhD, Liping Zhu, PhD |
2020-05-07 |
| A clinical study of anti-SARS-CoV-2 antibodies for the treatment of COVID-19 |
Coronavirus disease 19 infection |
anti-SARS-CoV-2 antibodies (COVID-19), AbCellera/Eli Lilly alone |
|
|
AbCellera Biologics Inc |
|
|
2020-07-31 |
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-05-05 |
| Effect of curcumin-piperine supplementation on disease duration, severity and clinical signs, and inflammatory factors in patients with coronavirus (COVID-19): A randomized, double-blind, placebo-controlled clinical trial study |
Coronavirus disease 19 infection |
curcumin capsules plus piperine capsules |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Isfahan University of medical Sciences |
|
Iran |
2020-05-04 |
|
IR.MUI.MED.REC.1399.049, IRCT20121216011763N46 |
Phase Not Applicable |
Recruiting |
1 |
|
100 |
Gholamreza Askari, Shaghayegh Haghjou |
2020-05-06 |
| Application of pulmonary rehabilitation exercise in the treatment of novel coronavirus pneumonia (COVID-19) patients during convalescence period |
Coronavirus disease 19 infection, Viral pneumonia |
pulmonary rehabilitation exercise alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Huazhong University of Science and Technology |
Beijing Chao-Yang Hospital |
China |
2020-05-01 |
2020-05-31 |
ChiCTR2000032457 |
Phase Not Applicable |
Not yet recruiting |
1 |
1 Month |
60 |
Wang Feng, Zhang Jianchu |
2020-05-06 |
| PLASCOSSA: Efficacy of Convalescent Plasma Therapy in the Early Care of COVID-19 Patients |
Coronavirus disease 19 infection |
SARS-CoV-2 convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Direction Centrale du Service de Sante des Armees |
University Hospital, Grenoble |
France |
2020-05-31 |
2021-05-31 |
2020-A01166-33, NCT04372979, PLASCOSSA |
Phase 3 Clinical |
Not yet recruiting |
4 |
12 Months |
80 |
Catherine VERRET, Christophe MARTINAUD, Christophe MARTINAUD, PU PH, Christophe RENARD, Cécile FICKO, Damien RICARD, Fabien DUTASTA, Hervé FOEHRENBACH, Hélène SAVINI, Jean-Luc BOSSON, Jean-Paul HYRIEN, Katia AVMART, Marc ALETTI |
2020-05-06 |
| Effects of convalescent plasma in COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
COVID-19 convalescent plasma alone, standard national guideline treatment alone |
|
|
Oroumia University of Medical Sciences |
Urmia University of Medical Sciences |
Iran |
2020-05-04 |
|
IR.UMSU.REC.1399.030, IRCT20200501047258N1 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
|
120 |
Iraj Mohebbi, Rahim Asgari, Rahim Asghari |
2020-05-06 |
| Clinical trial on Immunity and antiviral for quarantine patients of COVID-19 |
Coronavirus disease 19 infection, Immune disorder |
MyVir alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
MiLab LifeSciences (P) Ltd |
|
India |
2020-05-11 |
|
CT/MiLab/MyVir/2020, CTRI/2020/05/024967 |
Phase 4 Clinical |
Not yet recruiting |
1 |
|
30 |
Dr CR Jayanthi, MrLAKSHMANA PERUMAL SPT |
2020-05-07 |
| A Randomized Controlled Trial for the Effects of Low-Oxygen Consumption Instruction on the Prognosis of Patients with Novel Coronavirus Pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
low oxygen consumption alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Shanghai Public Health Clinical Center |
|
China |
2020-03-01 |
2020-05-01 |
ChiCTR2000032456 |
Phase Not Applicable |
Completed |
1 |
2 Months |
100 |
Shuihua Lu, Yang Yang |
2020-05-06 |
| TREAT NOW: Trial of Early Therapies During Non-hospitalized Outpatient Window for COVID-19 |
Coronavirus disease 19 infection, Respiratory tract infection |
hydroxychloroquine alone, lopinavir + ritonavir alone |
HIV protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Vanderbilt University Medical Center, US |
AbbVie Inc |
US |
2020-05-01 |
2021-05-01 |
200827, NCT04372628, TREAT NOW |
Phase 2 Clinical |
Not yet recruiting |
0 |
12 Months |
900 |
Adit A Ginde, MD, Lani L. Finck, Margaret A. Hays, Margaret Hays, Nathan I. Shapiro, M.D., Nathan L Shapiro, MD, Sharon Hayes, RN, Todd Rice, MD, Todd W. Rice, M.D., Todd W. Rice, MD |
2020-05-06 |
| The use of topical Povidone Iodine (PVP-I) oropharyngeal and intranasal application during the current coronavirus pandemic as a potential measure to reduce viral transmission |
Coronavirus disease 19 infection |
Povidone Iodine alone, standard oral antiviral therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
WIN MEDICARE PVTLTD |
Drugs Control Administration |
India |
2020-05-05 |
|
CTRI/2020/05/024962 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
96 |
Dr Sumita Shankar |
2020-05-07 |
| COST ACTION: Study for the Evaluation of Specific Antibodies Anti Covid-19 Linked to Covid-19 Infection, Symptoms and Genetic Expression of ACE2 Polymorphisms in Patients |
Coronavirus disease 19 infection |
BioMedomics COVID-19 IgM-IgG Rapid Test alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ospedale San Paolo |
|
Italy |
2020-03-30 |
2020-09-30 |
2020/ST/057, COST ACTION, NCT04367402 |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
600 |
Stefano Centanni, Full Professor |
2020-05-06 |
| Home Pulse Oximeter Use in Patients With COVID-19 |
Coronavirus disease 19 infection |
pulse oximetry alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Swedish Hospital |
|
US |
2020-03-20 |
2020-04-22 |
2020032301, NCT04373161 |
Phase Not Applicable |
Completed |
0 |
1 Month |
209 |
Kaushal Majmudar, Sonia Shah, DO |
2020-05-07 |
| MIA-COVID-19: Minimal Invasive Autopsies to Investigate Changes in Deceased COVID-19 Patients |
Coronavirus disease 19 infection |
CT-scan alone |
|
|
Jessa Hospital |
Antwerp University Hospital, Universiteit Hasselt |
Belgium |
2020-04-14 |
2020-12-31 |
JESSAH_COVID-19_MIA, MIA-COVID-19, NCT04366882 |
Phase Not Applicable |
Recruiting |
1 |
8 Months |
45 |
Jan Vanrusselt, MD, Janneke Cox, MD, PhD |
2020-05-06 |
| A study for the mental health status of novel coronavirus pneumonia (COVID-19) convalescent patients and first-line medical staff and Isolate residents and Hospital staffand the intervention strategy of psychological crisis in Ningxia |
Coronavirus disease 19 infection |
psychological crisis intervention alone |
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ningxia Medical University |
|
China |
2020-04-28 |
2021-12-31 |
ChiCTR2000032455 |
Phase 0 Clinical |
Recruiting |
1 |
20 Months |
140 |
Jiang Hong, Ma Xin-rong |
2020-05-06 |
| US3R: Health Care Use During the COVID-19 Crisis |
Coronavirus disease 19 infection |
online questionnaire alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universite Catholique de Louvain |
|
Belgium |
2020-05-01 |
2021-10-31 |
NCT04372030, US3R, US3R |
Phase Not Applicable |
Not yet recruiting |
1 |
18 Months |
10000 |
Dominique Vanpee, MD, Sandy Tubeuf, PhD |
2020-05-06 |
| RFCIM: RFCIM |
Coronavirus disease 19 infection |
|
|
|
Government of Malaysia |
|
Malaysia |
2020-05-01 |
2022-04-30 |
54832, NMRR-20-861-54832, RFCIM |
Phase Not Applicable |
Status not specified |
1 |
24 Months |
|
Associate Prof Dr Awang bulgiba awang mahmud, Devi Peramalah |
2020-05-14 |
| Economic burden of COVID-19 in Malaysia |
Coronavirus disease 19 infection |
|
|
|
Government of Malaysia |
|
Malaysia |
2020-05-04 |
2022-12-19 |
54823, NMRR-20-865-54823 |
Phase Not Applicable |
Not yet recruiting |
1 |
31 Months |
|
Dr Amirah binti Azzeri, Dr Maznah Dahlui |
2020-05-07 |
| Clinical characteristics of renal patients with COVID-19 infection |
Coronavirus disease 19 infection, Renal failure |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Nierenzentrum Heidelberg |
|
Germany |
2020-04-06 |
|
DRKS00021295, S-223/202 |
Phase Not Applicable |
Recruiting |
1 |
|
100 |
Claudia Sommerer |
2020-05-07 |
| A multicenter, randomized, open comparative clinical trial of the drug Favipiravir in patients hospitalized with COVID-19 |
Coronavirus disease 19 infection |
favipiravir alone |
RNA polymerase inhibitor |
|
ChemRar High Tech Center, Russian Direct Investment Fund |
|
Russian Federation |
2020-04-28 |
|
|
Phase 2 Clinical |
Recruiting |
3 |
|
330 |
|
2020-05-05 |
| Convalescent Plasma for the Treatment of Patients With COVID-19 |
Coronavirus disease 19 infection, Dyspnea, Respiratory failure |
COVID-19 convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Colorado, Denver, US |
|
US |
|
|
20-0990, NCT04372368 |
Phase Not Applicable |
Recruiting |
0 |
|
|
John D Beckham, MD |
2020-05-06 |
| A clinical trial of XRx-101 for prevention of acute kidney injury due to coronavirus/COVID-19 infection |
Coronavirus disease 19 infection, Renal injury |
oxypurinol (acute kidney injury/lung injury/COVID-19), XORTX Therapeutics alone |
Xanthine oxidase inhibitor |
|
XORTX Therapeutics Inc |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-05-05 |
| A clinical trial of Wyss-designed swabs for COVID-19 |
Coronavirus disease 19 infection |
Wyss-designed swabs alone |
|
|
Wyss Institute for Biologically Inspired Engineering |
|
US |
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-05-08 |