Last updated: May 21, 2020 - 02:00 BST

Title Indication Intervention Actions PatientSelection Sponsor Collaborator Country StartDate EndDate Identifiers Phase Recruitment Status Sites Trial Duration Enrollment Count Contacts LastChanged
RHUMACOVID: Drug Management of Rheumatoid Arthritis in COVID-19 Context: Impact on Therapeutic De-escalation Coronavirus disease 19 infection, Rheumatoid arthritis DMARD therapy management alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Brest France 2020-04-23 2020-05-23 NCT04393233, RHUMACOVID, RHUMACOVID (29BRC20.0110) Phase Not Applicable Recruiting 0 1 Month 300 Dewi GUELLEC, Dewi Guellec, Valerie Devauchelle 2020-05-20
An Observational Study to Assess the Incidental Findings Suggestive of COVID-19 in Asymptomatic Patients Undergoing Nuclear Medicine Procedures in a High-Prevalence Region Coronavirus disease 19 infection 131-iodine alone, 18F-FDG alone, PET/CT alone, SPECT/CT alone Universita degli Studi di Brescia Italy Phase Not Applicable Status not specified 0 77 2020-05-20
Impact of Covid-19 Pandemic on Depression and Quality of Life Coronavirus disease 19 infection, Depression Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Okan University Yuksek İhtisas University Turkey 2020-05-06 2020-05-18 56665618-204.01.07, NCT04394078 Phase Not Applicable Recruiting 0 500 Begum Okudan 2020-05-20
Low Dose Radiation Therapy for Covid-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia low dose radiation therapy (70 cGy) alone, standard therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences India 2020-06-30 2021-06-30 COVID-AIIMS, NCT04394793 Phase Not Applicable Not yet recruiting 0 12 Months 10 Daya Nand Sharma, MD, Randeep Guleria, MD, Supriya Mallick, MD 2020-05-20
SCOPE: Silymarin in COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia silymarin alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cairo University Egypt 2020-06-01 2020-09-30 CAIROU COVID-19 STUDY GROUP, NCT04394208, SCOPE Phase 3 Clinical Not yet recruiting 0 4 Months 50 Khaled Mohammed Korany Salem, Khaled Salem, MSc, Khaled Salem, Msc, Mostafa Alfishawy, Consultant, Mostafa Alfishawy, MD 2020-05-20
Amotosalen-Ultraviolet A Pathogen-Inactivated Convalescent Plasma in Addition to Best Supportive Care and Antiviral Therapy on Clinical Deterioration in Adults Presenting With Moderate to Severe COVID-19 Coronavirus disease 19 infection, SARS coronavirus infection INTERCEPT Blood System alone, convalescent plasma alone, standard of care alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) University Hospital Basel Switzerland 2020-03-31 2020-06-30 NCT04389944, REQ-2020-00508, ME20KHANNA2 Phase Not Applicable Recruiting 0 3 Months 15 Andreas Buser, Prof. Dr. MD, Andreas Buser, Prof. Dr. med., Maja Weisser, Prof. Dr. med., Manuel Battegay, Prof. Dr. med., Nina Khanna, Prof. Dr. MD, Nina Khanna, Prof. Dr. med 2020-05-20
ULTRA-COVID: Ultra Low Doses of Therapy With Radiation Applicated to COVID-19 Coronavirus disease 19 infection, Inflammatory disease, Viral pneumonia Ventimask alone, nasal cannula alone, oxygen therapy alone, ultra-low-dose radiotherapy (0.8 Gy) alone, Variable regimens including Urbason , azithromycin , hydroxychloroquine (Dolquine) , lopinavir + ritonavir , low molecular weight heparin , piperacillin + tazobactam , tocilizumab HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundacion GenesisCare Hospital La Milagrosa, Hospital Vithas Valencia Consuelo Spain 2020-04-21 2021-04-21 20.4.1597-GHM, NCT04394182, ULTRA-COVID Phase 2 Clinical Recruiting 0 12 Months 15 Elena Moreno Olmedo, MD, Escarlata López Ramírez, MD, PhD, Luis María Larrea Rabassa, MD, Manuel Pérez Fernández, MD 2020-05-20
Mir-Age: ABX-464 in Treating Inflammation and Preventing Acute Respiratory Failure in Patients With COVID-19 Coronavirus disease 19 infection, Inflammatory disease, Respiratory failure ABX-464 alone, standard of care alone Rev protein modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Abivax SA Bpifrance Europe, France 2020-05-01 2021-04-30 ABX464-401, Mir-Age, NCT04393038 Phase 2/Phase 3 Clinical Recruiting 0 12 Months 1034 Anais Vissian, Eric CUA, MD, Paul GINESTE 2020-05-20
Using Cord Blood in Treatment of COVID-19 Coronavirus disease 19 infection cord blood stem cells alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Aljazeera Hospital Egypt 2020-05-20 2020-08-01 COVID -19, NCT04393415 Phase 2 Clinical Not yet recruiting 0 2 Months 100 Mahmoud Alalfy, PhD 2020-05-20
Efficacy of Kelofan syrup on COVID-19 Coronavirus disease 19 infection Kelofan syrup alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ardabil University of Medical Sciences Iran 2020-05-17 2020-07-05 IR.ARUMS.REC.1399.009, IRCT20200405046960N2 Phase 2/Phase 3 Clinical Recruiting 0 1 Month 60 Ramin Nasimi Doost Azgomi 2020-05-20
Longitudinal, COVID-19 Cohort Study Coronavirus disease 19 infection, Respiratory failure Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Vermont US 2020-04-16 2023-05-31 CHRMS 16-540, NCT04393155 Phase Not Applicable Recruiting 0 37 Months 225 Arooj Fatima, Dale Needham, MD, PhD, Renee D Stapleton, MD, PhD, Sara S Ardren, PA 2020-05-20
COVID19IF: Imaging Feature of SARS-CoV2 Infection Coronavirus disease 19 infection IRCCS San Raffaele Italy 2020-04-16 2020-10-01 COVID-19 IF, COVID19IF, NCT04394026 Phase Not Applicable Recruiting 0 5 Months 500 Carlo Martinenghi, MD, Francesco De Cobelli, Francesco De Cobelli, MD, Stephanie Steidler, PhD 2020-05-20
Serological Testing of Household Contacts of Confirmed Cases of COVID-19 Coronavirus disease 19 infection COVID-19 IgM/IgG test kit (Singclean) alone, serological test alone Healthy volunteers accepted, Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Universitario Dr. Jose E. Gonzalez Mexico 2020-05-05 2020-06-01 IF20-00004, NCT04393142 Phase Not Applicable Recruiting 0 92 Adrian Camacho, PhD, Adrian Camacho-Ortiz, MD, Adrian Camacho-Ortiz, PhD, Eduardo Pérez Alba, MD, Edurdo Pérez Alba, MD, Gloria Mayela Aguirre García, MD, Jaime Eugenio Espinosa Mora, MD, Laura Marina Nuzzolo Shihadeh, MD 2020-05-20
LUS-COVID19: Lung Ultrasound Score in Covid-19 Infectious Disease in Critical Care Coronavirus disease 19 infection, Respiratory distress syndrome lung ultrasound (LUS) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire De Nice France 2020-03-20 2020-12-31 20REAMEDCOVID03, LUS-COVID19, NCT04393402 Phase Not Applicable Recruiting 0 9 Months 14 Jean DELLAMONICA, Jean DELLAMONICA, MD, PhD, Romain LOMBARDI 2020-05-20
Trial of Imatinib for Hospitalized Adults With COVID-19 Coronavirus disease 19 infection imatinib alone Abl tyrosine kinase inhibitor, Bcr protein inhibitor, Kit tyrosine kinase inhibitor, PDGF receptor antagonist, Signal transduction inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Maryland US 2020-05-20 2023-06-01 2038GCCC, NCT04394416 Phase 3 Clinical Not yet recruiting 0 36 Months 204 Ashkan Emadi, MD, PhD, Monica Estrada 2020-05-20
PROVENT-COVID: Accelerated Prone Position Ventilation of Patients With COVID-19 Coronavirus disease 19 infection Prone position ventilation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Nordsjaellands Hospital Denmark 2020-05-11 2020-12-31 H-20027361, NCT04384900, PROVENT-COVID Phase Not Applicable Recruiting 0 7 Months 150 Morten H Bestle, MD, PhD, Morten H Bestle, MD,PhD, Theis S Itenov, MD, PhD, Theis S Itenov, MD,PhD 2020-05-20
COVID-PRONE: Prone Positioning for Patients on General Medical Wards With COVID19 Coronavirus disease 19 infection Prone positioning alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) St Michaels Hospital Sinai Health System, Sunnybrook Health Sciences Centre, The University Health Network, Toronto General Hospital Canada 2020-05-11 2020-12-11 2020-1, COVID-PRONE, NCT04383613 Phase Not Applicable Not yet recruiting 0 7 Months 350 Amol Verma, MD, MPhil, Fahad Razak, MD, MSc, Michael Fralick, MD, PhD 2020-05-20
CoVInnate: Role of Inflammasomes in COVID-19 Disease Coronavirus disease 19 infection DNA analysis alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire De Nice France 2020-05-11 2021-06-12 20-PP-07, CoVInnate, NCT04385017 Phase Not Applicable Recruiting 0 13 Months 40 COURJON JOHAN, PH, COURJON JOHAN, Ph, COURJON Johan, COURJON Johan, Ph, CUA ERIC, PH, Cua Eric, Ph, ROBERT Alexandre, ROBERT Alexandre, Ph 2020-05-20
Seroprevalence of SARS CoV 2 Antibodies in Previously Undiagnosed Healthcare Workers Coronavirus disease 19 infection Serologic testing alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mayo Clinic Foundation US 2020-05-06 2020-06-12 20-004054, NCT04383587 Phase Not Applicable Recruiting 0 1 Month 300 Mark Parkulo, MD 2020-05-20
COVIDVIT: Do Vitamin D Levels Really Correlate With Disease Severity in COVID-19 Patients? Coronavirus disease 19 infection vitamin D alone Bursa City Hospital Turkey 2020-05-01 2020-06-30 1, COVIDVIT, NCT04394390 Phase Not Applicable Recruiting 0 2 Months 100 Taner Dandinoğlu 2020-05-20
Convalescent Plasma and Placebo for the Treatment of COVID-19 Severe Pneumonia Coronavirus disease 19 infection, Viral pneumonia Convalescent SARS COVID-19 plasma alone, standard care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Italiano de Buenos Aires Argentina 2020-05-15 2020-08-20 5565, NCT04383535 Phase Not Applicable Not yet recruiting 0 3 Months 333 Claudia Salgueira, Esteban Nannini, Fernando Palizas, Florencia Otermin, Francisco Klein, Gustavo Lopardo, Javier Altclas, Javier Sarro, Karina Rainiero, Laura Barcelona, Liliana Sarro, Marcelo Losso, Mariangeles Fenes, Matias Lahitte, Nadia Ahmed, Nora A Fuentes, MD, Pablo Gutierrez, Ricardo Valentini, Santiago Ramirez Borga, Ventura Simonovich, MD, Waldo H Belloso, PhD 2020-05-20
TACTIC-E: Multi-arm Therapeutic Study in Pre-ICU Patients Admitted With Covid-19 - Experimental Drugs and Mechanisms Coronavirus disease 19 infection, Multiple organ failure EDP-1815 alone, standard of care alone, ambrisentan plus dapagliflozin propanediol Endothelin ET-A receptor antagonist, Sodium glucose transporter-2 inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cambridge University Hospitals NHS Foundation Trust UK 2020-05-20 2021-05-20 NCT04393246, TACTIC-E, TACTIC-E Phase 2/Phase 3 Clinical Not yet recruiting 0 12 Months 1407 Joseph Cheriyan, MBChB MA FRCP, Sonakshi Kadyan, BTech MRes 2020-05-20
CLARITY: Controlled evaluation of Angiotensin Receptor Blockers for COVID-19 respiratory Disease Coronavirus disease 19 infection, Respiratory disease candesartan alone, eprosartan alone, irbesartan alone, losartan alone, olmesartan medoxomil alone, standard care alone, telmisartan alone, valsartan alone Angiotensin I receptor antagonist, Angiotensin II AT-1 receptor antagonist, Angiotensin II receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The George Institute for Global Health Australia 2020-05-20 2021-04-30 11052020, CLARITY, NCT04394117 Phase 4 Clinical Not yet recruiting 0 11 Months 605 Arlen Wilcox, Carol Pollock, Greg Fox, Louisa Sukkar, Meg Jardine 2020-05-20
HETHICO: Heparins for Thromboprophylaxis in COVID Patients: HETHICO Study in Veneto Coronavirus disease 19 infection, Thrombosis enoxaparin sodium alone Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Quovadis Associazione University of Padua Italy 2020-06-30 2020-12-31 HETHICO, HETHICO, NCT04393805 Phase Not Applicable Not yet recruiting 0 6 Months 877 Paolo Simioni, Prof. 2020-05-20
First Level Socio-geriatric Evaluation: ESOGER Databank Coronavirus disease 19 infection, Muscle weakness ESOGER questionnaire alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sir Mortimer B Davis Jewish General Hospital Canada 2020-04-20 2021-04-19 MP-05-2021-2308, NCT04393649 Phase Not Applicable Recruiting 0 12 Months 20000 Kevin Galery, Olivier Beauchet, MD 2020-05-20
KoCo19: Prospective COVID-19 Cohort Munich Coronavirus disease 19 infection Klinikum der Universitat Muenchen Deutsche Forschungsgemeinschaft (DFG), German Federal Ministry of Education and Research, Staatsministerium fur Wissenschaft und Kunst Germany 2020-04-07 20-275, DRKS00021698, KoCo19 Phase Not Applicable Recruiting 0 6000 Michael Hoelscher, Michael Pritsch 2020-05-20
FACCT: Favipiravir and Hydroxychloroquine Combination Therapy Coronavirus disease 19 infection favipiravir plus hydroxychloroquine RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) King Abdullah International Medical Research Center Saudi Arabia 2020-05-31 2021-11-30 FACCT, NCT04392973, RC20/174 Phase 2 Clinical Not yet recruiting 0 18 Months 520 Majed Al Jeraisy, Mohammad Bosaeed, Mohammad Bosaeed, MD 2020-05-20
A trial to assess IBIO-200 for potential treatment of COVID-19 Coronavirus disease 19 infection IBIO-200 alone iBio Inc Phase Not Applicable Planned 0 2020-05-20
Telepharmacy, inhaler technique, satisfaction, COVID-19 Coronavirus disease 19 infection telepharmacy counseling alone Hospital Sungai Buloh Malaysia 2020-05-15 2020-09-30 54975, NMRR-20-951-54975 Phase Not Applicable Status not specified 0 4 Months MS KALAIVANI A/P SUBRAMANIAM 2020-05-20
At-Home COVID-19 Antibody Test Usability Assessment and Behavior Change Study Coronavirus disease 19 infection Premier Biotech COVID-19 IgG/IgM Rapid test Cassette alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) ProofPilot Radish Health, Sanesco Bv US 2020-04-05 2020-08-29 2458, NCT04393961 Phase Not Applicable Recruiting 0 4 Months 600 Matthew Amsden, Viral Patel, MD 2020-05-20
TubeObs-Covid: Endotracheal Tube Obstruction in COVID-19 Patients Requiring Mechanical Ventilation Coronavirus disease 19 infection, Respiratory disease mechanical ventilation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopitaux Universitaires de Strasbourg France 2020-04-24 2020-06-24 7803, NCT04394429, TubeObs-Covid Phase Not Applicable Recruiting 0 2 Months 184 Bob HEGER, MD, Saïd CHAYER, PhD, HDR 2020-05-20
COVID-Net Validation Coronavirus disease 19 infection Selayang Hospital Malaysia 2020-05-15 2020-12-14 54941, NMRR-20-949-54941 Phase Not Applicable Status not specified 0 7 Months Hafiz Git Kim Ann 2020-05-20
Lung Irradiation for COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia bilateral lung irradiation (100 cGy) alone, single lung irradiation (100 cGy) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Brigham & Women's Hospital US 2020-05-31 2020-11-30 2020P001494, NCT04393948 Phase Not Applicable Not yet recruiting 0 6 Months 36 David Kozono, MD, PhD, Thomas Johnson, MS 2020-05-20
COALIZAO ACTION: Full Anticoagulation Versus Prophylaxis in COVID-19 Blood clotting disorder, Coronavirus disease 19 infection, Thromboembolism azithromycin alone, enoxaparin sodium alone, rivaroxaban alone, routine full anticoagulation strategy therapy alone, unfractionated heparin alone, Variable regimens including azithromycin , enoxaparin sodium , rivaroxaban , unfractionated heparin Factor Xa antagonist, Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Brazilian Clinical Research Institute Sociedade Beneficente Israelita Brasileira Hospital Albert Einsten Brazil 2020-05-31 2020-12-31 002/2020, COALIZAO ACTION, NCT04394377 Phase 4 Clinical Not yet recruiting 0 7 Months 600 Renato D. Lopes, MD, PhD 2020-05-20
COVIDsFlt1: sFlt1: a Biomarker of Organ Dysfunction in Critically-ill Patients With COVID-19? Coronavirus disease 19 infection, Multiple organ failure, Vascular disease Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire de Reims France 2020-03-25 2020-09-01 COVIDsFlt1, NCT04394195, PO20043* Phase Not Applicable Recruiting 0 5 Months 200 Damien JOLLY 2020-05-20
Efficacy of Ivermectin in COVID-19 Coronavirus disease 19 infection chloroquine plus ivermectin Chloride channel modulator Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Combined Military Hospital, Pakistan Pakistan 2020-04-15 2020-07-31 IVE-COV, NCT04392713 Phase 2 Clinical Recruiting 0 3 Months 100 Asma Asghar, Asma Asghar, FCPS MED, Karamat Hu Bukhari, FCPS MED, Najma Parveen, FCPS MED, Najma Parveen, FCPS med 2020-05-20
MaastrICCht: Serial measurements in COVID-19-induced acute respiratory disease to unravel heterogeneity of the disease course: design of the Maastricht Intensive Care COVID cohort Coronavirus disease 19 infection Maastricht University Medical Center Netherlands 2020-03-23 2022-03-23 MaastrICCht, NL8613 Phase Not Applicable Recruiting 0 24 Months 250 Bas van Bussel 2020-05-20
BARICIVID-19: Baricitinib Compared to Standard Therapy in Patients With COVID-19 Coronavirus disease 19 infection, Viral pneumonia standard therapy alone, Variable regimens including baricitinib , chloroquine , darunavir + ritonavir , idrossichloroquine , lopinavir + ritonavir , low-molecular weight heparin HIV protease inhibitor, Jak1 tyrosine kinase inhibitor, Jak2 tyrosine kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Azienda Ospedaliero, Universitaria Pisana Italy 2020-05-20 2020-07-30 BARICIVID-19, BARICIVID-19, NCT04393051 Phase 2a Clinical Not yet recruiting 0 2 Months 126 Francesco Menichetti, Francesco Menichetti, MD, Giusy Tiseo, MD, Marco Falcone, Marco Falcone, MD 2020-05-20
Ulinastatin for the Treatment of COVID-19 in Hospitalized Patients Coronavirus disease 19 infection ulinastatin alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Stanford University US 2020-06-30 2020-12-31 56639, NCT04393311 Phase 1/Phase 2 Clinical Not yet recruiting 0 6 Months 150 Kevin V Grimes, MD 2020-05-20
COVID-19 Wellness Survey Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rutgers University US 2020-05-15 2020-05-31 NCT04394104, PRO2020001009 Phase Not Applicable Not yet recruiting 0 1000 Alexandra DelCollo, Alexandra M DelCollo, MS, Sara Elnakib, MPH 2020-05-20
Wearable Sensor to Monitor COVID-19 Like Signs and Symptoms Coronavirus disease 19 infection ADAM Sensor alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rehabilitation Institute Of Chicago US 2020-04-20 2022-12-31 NCT04393558, STU00212522 Phase Not Applicable Recruiting 0 32 Months 100 Arun Jayaraman, Arun Jayaraman, PhD, Lori McGee Koch, Lori McGee Koch, PhD 2020-05-20
OnCovid: COVID-19 and Cancer Patients Cancer, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Imperial College London UK 2020-03-24 2022-03-24 282140, NCT04393974, OnCovid Phase Not Applicable Recruiting 0 24 Months 50 David J Pinato, MD 2020-05-20
Tetrix: The Critical Care Response to the COVID-19 Pandemic in Madrid Coronavirus disease 19 infection Healthy volunteers accepted Hospital Clinico San Carlos Instituto de Investigación Sanitaria del Hospital Clínico San Carlos Spain 2020-04-24 2020-06-30 MADRID COVID TETRIX, NCT04393324, Tetrix Phase Not Applicable Recruiting 0 2 Months 2000 Antonio S Núñez Reiz, Miguel S Sanchez Garcia, MD, Miguel Sanchez Garcia, MD. PhD, Miguel Sánchez García, MD 2020-05-20
A clinical study of hydroxychloroquine and azithromycin in the treatment of patients with COVID-19 Coronavirus disease 19 infection azithromycin alone, hydroxychloroquine alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Oxford UK 2020-05-12 Phase Not Applicable Recruiting 0 Chris Butler 2020-05-19
PIA: COVID-19 Pandemic Impact on Alcohol (PIA): A Natural History Study Alcoholism, Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute on Alcohol Abuse and Alcoholism National Institutes of Health Clinical Center US 2020-05-22 2024-12-31 20-AA-N115, 999920115, NCT04391816, PIA Phase Not Applicable Recruiting 0 55 Months 700 Vijay A Ramchandani, Ph.D., Vijay Ramchandani, Ph.D. 2020-05-20
DICER: Dipyridamole to Prevent Coronavirus Exacerbation of Respiratory Status in COVID-19 Blood clotting disorder, Coronavirus disease 19 infection dipyridamole alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Michigan US 2020-06-30 2020-12-31 DICER, HUM00179783, NCT04391179 Phase 2 Clinical Not yet recruiting 0 6 Months 80 Neha Shah, Yogendra Kanthi, MD 2020-05-20
The Use of Peripheral Blood Specimens From Patients Suspected of Having SARS-CoV-2 Infections in Research Studies Intended to Support the Development of COVID-19 Detection Methods, Treatments, and/or Vaccines Coronavirus disease 19 infection COVID-19 testing alone Invivoscribe Technologies Inc US 2020-06-01 2021-06-30 IVS-000-002, NCT04391400 Phase Not Applicable Not yet recruiting 0 13 Months 500 Ellen F Harris, BS, Jason Gerhold, Jordon Thornes 2020-05-20
Hydroxychloroquine and Ivermectin for the Treatment of COVID-19 Infection Coronavirus disease 19 infection, Respiratory tract infection, Viral pneumonia hydroxychloroquine plus ivermectin Chloride channel modulator Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centenario Hospital Miguel Hidalgo Mexico 2020-05-04 2020-09-30 2020-A-09, NCT04391127 Phase 3 Clinical Recruiting 0 4 Months 200 Jose Manuel Arreola Guerra, MD, MSc, PhD, Lucila Martinez, MDPhD, Mario Gonzalez Gamez, MD, Victor Monroy, MD 2020-05-19
ICMR – RUMC COVID 19: Questionnaire based study of drugs taken by healthcare workers to prevent COVID 19 Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Indian Council of Medical Research India 2020-05-18 CTRI/2020/05/025183, ICMR – RUMC COVID 19 Phase Not Applicable Not yet recruiting 0 5000 Dr Bikash Medhi, Dr C D Tripathi, Dr Chetna Desai, Dr Denis Xavier, Dr Dinesh K Badyal, Dr Niyati Trivedi, Dr Pooja Gupta, Dr R Raveendran, Dr S Balakrishnan, Dr Sandeep Kaushal, Dr Sandhya Kamat, Dr Santanu K Tripathi, Dr Sujith Chandy, Dr Suparna Chatterjee, DrHarihar Dikshit 2020-05-20
Global Snapshot of Covid19 patients with kidney dysfunction Coronavirus disease 19 infection, End stage renal disease, Renal injury chronic dialysis alone Hospital Kuala Lumpur Malaysia 2020-05-15 2021-08-11 54867, NMRR-20-911-54867 Phase Not Applicable Not yet recruiting 0 14 Months 200 Dr Ching Chen Hua, Dr EDDIE WONG FOOK SEM, Dr Liu Wen Jiun, Dr Loh Chek Loong, Dr Maisarah Binti Jalalonmuhali, Dr NURUL ZAYNAH BINTI NORDIN, Dr Ruslinda Bt Mustafar, Dr Sunita Bavanandam 2020-05-20
New Antiviral Drugs for Treatment of COVID-19 Coronavirus disease 19 infection Variable regimens including ivermectin , nitazoxanide , ribavirin , zinc Chloride channel modulator Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mansoura University Egypt 2020-05-31 2022-05-31 20.05.69, NCT04392427 Phase 3 Clinical Not yet recruiting 0 24 Months 100 HATEM ELALFY, HATEM ELALFY, MD, TAREK BESHEER, MD 2020-05-19
HCQ for COVID-19 Coronavirus disease 19 infection hydroxychloroquine alone Hospital Kuala Lumpur Malaysia 2020-06-01 2021-06-01 54901, NMRR-20-910-54901 Phase Not Applicable Not yet recruiting 1 12 Months 450 Dr. How Kang Nien 2020-05-20
Evaluation of the effect of trans sodium crocetinate in respiratory distress caused by COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome standard treatment regimen therapy alone, trans sodium crocetinate alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Mashhad University of Medical Sciences Iran 2020-06-21 IR.MUMS.REC.1399.245, IRCT20081019001369N6 Phase 2 Clinical Not yet recruiting 1 30 Amirhoushang Mohammadpour, Hossein Hosseinzadeh, Mohsen Tafaghodi 2020-05-20
HCQ POCKET ECG Ambulatory Telemetry Study Coronavirus disease 19 infection hydroxychloroquine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) All India Institute Of Medical Sciences, Rishikesh, MEDICALgorithmics India 2020-05-26 CTRI/2020/05/025216 Phase Not Applicable Not yet recruiting 0 30 Rohit Walia 2020-05-20
Effectiveness of Siddha medicine, Kabasura kudineer and vitamin c-zinc supplementation in the management of Mild COVID 19 patients Coronavirus disease 19 infection Kabasura Kudineer alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Central Council for Research in Siddha, Government Stanley Medical College Hospital India 2020-05-25 CTRI/2020/05/025215 Phase 1/Phase 2 Clinical Not yet recruiting 0 50 Dr C Anbarasi, Dr S Natarajan 2020-05-20
A randomized controlled trial for the efficacy and safety of artemisinin-pipequine tablets in the treatment of the mild and common type novel coronavirus pneumonia (COVID-19) patients whose nCoV Nucleic acid did not turn negative after treated by hydroxychloroquine and Abidor Coronavirus disease 19 infection artemisinin + pipequine alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hongqi hospital of Mudanjing medical university Guangzhou University of Traditional Chinese Medicine China 2020-05-07 2020-12-31 ChiCTR2000032915 Phase 4 Clinical Recruiting 0 7 Months 240 Fengjie Xie, Hongying Zhang 2020-05-20
A clinical trial to study the efficacy of convalescent plasma therapy in COVID-19 patients Coronavirus disease 19 infection convalescent plasma therapy alone Government of India Council of Scientific and Industrial Research (India) India Phase Not Applicable Not yet recruiting 1 Biswanath Sharma Biswas, Shekhar Ranjan Paul, Yogiraj Roy 2020-05-19
Cold Laser Therapy for COVID-19 Positive Patients With Pulmonary Disease Coronavirus disease 19 infection, Lung disease MLS laser alone, regular inpatient medical care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Lowell General Hospital US 2020-04-30 2020-06-30 2020.01, NCT04391712 Phase 2 Clinical Recruiting 0 2 Months 20 Michael McAuliffe, Scott Sigman, MD 2020-05-20
HCW COVID Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sultanah Nur Zahirah Hospital Malaysia 2020-05-28 2020-07-31 54858, NMRR-20-909-54858 Phase Not Applicable Not yet recruiting 0 2 Months 400 nurul ashikin binti adnan 2020-05-20
Traditional Chinese Medicine (TCM); Coronavirus disease 2019 (COVID-19) Coronavirus disease 19 infection, Cough Traditional Chinese Medicine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) National Cancer Institute - Malaysia Malaysia 2020-05-25 2020-08-25 54907, NMRR-20-940-54907 Phase Not Applicable Not yet recruiting 0 3 Months 120 Dr Teo Chiah Shean 2020-05-20
Investigating the Effect of BCG Vaccine on Preventing COVID-19 Infection in Healthcare Staff Exposed to SARS-CoV-2 Coronavirus disease 19 infection BCG vaccine alone, Mantoux Tuberculin alone, tuberculin test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shiraz University of Medical Sciences Iran 2020-06-04 IR.SUMS.REC.1399.181, IRCT20200411047019N1 Phase 3 Clinical Not yet recruiting 4 500 Ali Akbari, Bahman Pourabbas, GHolamreza Pouladfar, Gholamreza Pouladfar, Mohsen Moghadami, Mohsen Moghademi 2020-05-20
Hyperimmune Convalescent Plasma in Moderate and Severe COVID-19 Disease Coronavirus disease 19 infection, Viral pneumonia convalescent hyperimmune plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Federal Medical Biological Agency Russian Federation 2020-05-01 2020-09-15 COVPLAS-COVID19, NCT04392414 Phase 2 Clinical Recruiting 1 4 Months 60 Alexander V Averyanov, MD, PhD, Mikhail A Konoplyannikov, PhD, Vladimir P Baklaushev, MD, PhD 2020-05-20
A clinical trial of BDCA-04 for the treatment of Acute Respiratory Distress Syndrome due to COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome BDCA-04 alone BioCardia Inc Phase not specified Status not specified 0 2020-05-19
NIRS-COV: Effects of Cardiovascular and Pulmonary Optimization on Cerebral Oxygenation in COVID-19 Patients With Severe ARDS Adult respiratory distress syndrome, Coronavirus disease 19 infection, Hypoxia LiDCO alone, near-infrared spectroscopy alone, pulse oxymetry (Massimo) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) HS Hvidovre Hospital Denmark 2020-05-01 2021-05-01 H-20027818, NCT04392089, NIRS-COV Phase Not Applicable Recruiting 1 12 Months 20 Ana-Marija Hristovska, MD, Ana-Marija Hristovska, MD, Ph.d.-student 2020-05-19
Hydroxychloroquine, azithromycin and QT-prolongation Coronavirus disease 19 infection azithromycin plus hydroxychloroquine Taiping Hospital Malaysia 2020-05-19 2020-05-29 55091, NMRR-20-986-55091 Phase Not Applicable Status not specified 1 Dr Hor Chee Peng 2020-05-20
ICPHAM: ICPHAM Coronavirus disease 19 infection Ministry of Health, Malaysia Malaysia 2020-05-25 2021-12-31 54777, ICPHAM, NMRR-20-989-54777 Phase Not Applicable Status not specified 1 19 Months Dr Nur Wahida Binti Zulkifli 2020-05-19
Phase II, IC14 (Anti-CD14) Treatment in Patients With SARS-CoV-2 (COVID-19) Coronavirus disease 19 infection, Lung infection, Respiratory disease, Respiratory failure IC-14 alone Monocyte differentiation antigen CD14 inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Implicit Bioscience Ltd University of Washington US 2020-07-31 2021-09-30 COV04, NCT04391309 Phase 2 Clinical Not yet recruiting 0 14 Months 300 Mark Wurfel, MD, PhD 2020-05-19
Colchicine Plus Phenolic Monoterpenes to Treat COVID-19 Coronavirus disease 19 infection, Viral pneumonia standard treatment alone, colchicine plus herbal phenolic monoterpene fractions Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kermanshah University of Medical Sciences Iran 2020-04-01 2020-10-01 1399.062, NCT04392141 Phase 1/Phase 2 Clinical Recruiting 1 6 Months 200 Ahmad Bagheri, MSc, Ali Mostafaie, PhD, Alireza Janbakhsh, MD, Farhad Abdali, BSc, Farid Najafi, MD, PhD, Kavyan Fatahpour, MSc, Mohammad H Zamanian, MD, Siavash Vaziri, MD, Yadollah Shakiba, MD, PhD 2020-05-19
Assessment of boron-containing compounds and Oleoylethanolamide supplementation on the recovery trend in Patients with COVID-19: A double-blind, randomized, placebo-controlled clinical trial Coronavirus disease 19 infection boron containing compound alone, oleoylethanolamide alone, boron containing compound plus oleoylethanolamide Tabriz University of Medical Sciences Iran 2020-05-19 IR.TBZMED.REC.1399.099, IRCT20090609002017N35 Phase 2 Clinical Recruiting 1 40 Alireza Ostadrahimi 2020-05-20
A clinical trial of TargNaturTa, Off-the-Shelf T Cell Therapy for the prevention of COVID-19 Coronavirus disease 19 infection TargNaturTa alone Geneius Biotechnology Ltd Phase Not Applicable Planned 0 2020-05-20
BMI-SARSCoV2: Association Between BMI and SARS-CoV-2 Coronavirus disease 19 infection, Obesity Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Regional Universitaire de Lille France 2020-02-01 2020-09-30 BMI-SARSCoV2, DEC20-095, NCT04391738 Phase Not Applicable No longer recruiting 1 8 Months 1200 Francois Pattou, MD 2020-05-20
HYACINTHE: Randomized, Double-blind, Placebo-controlled, Phase II Study Evaluating the Efficacy of Hydroxychloroquine and Azithromycin in Patients With COVID-19 and Hematological Malignancies Coronavirus disease 19 infection, Hematological neoplasm azithromycin plus hydroxychloroquine Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institut de Cancerologie Strasbourg Europe France 2020-05-12 2021-01-31 2020-002002-45, 2020-005, HYACINTHE, NCT04392128 Phase 2 Clinical Not yet recruiting 1 8 Months 114 Anne QUINQUENEL, MD, Bernard DRENOU, MD, Denis CAILLOT, MD, Etienne DAGUINDAU, MD, Luc-Matthieu FORNECKER, MD-PhD, Manon VOEGELIN, Marie Thérèse RUBIO, MD-PhD, Philippe CARASSOU, MD, Stéphanie NGUYEN QUOC, MD-PhD, Valérie SARTORI 2020-05-20
Effect of colchicine in treatment of COVID-19 Coronavirus disease 19 infection colchicine plus hydroxychloroquine Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Shahid Sadoughi University of Medical Sciences and Health Services Iran 2020-04-04 IR.SBMU.NRITLD.REC.1399.018, IRCT20190810044500N5 Phase 3 Clinical Recruiting 1 200 Dr.Fateme Saghafi, Masoud Mirzaei, Nadia Soltani Gerdefaramarzi, Nadia Soltani gerdefaramarzi 2020-05-20
LOGIC: The symptoms, virology and immunity of COVID in healthcare workers Coronavirus disease 19 infection University of Bristol The Grand Appeal UK 2020-03-23 2021-12-31 IRAS 282718, ISRCTN44324934, LOGIC Phase Not Applicable Recruiting 1 21 Months 135 Prof Finn 2020-05-20
Therapeutic plasma exchange (removal of the non-cell portion of blood) in critically ill adult patients with serious SARS CoV-2 disease (COVID-19) Coronavirus disease 19 infection Depuro D2000 Adsorption Cartridge alone, Spectra Optia Apheresis System alone, antibiotics therapy alone, fluid resuscitation alone, mechanical (ARDS-net and prone position) ventilation alone, vasoactive substances therapy alone, hydroxychloroquine plus therapeutic plasma exchange Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) King Saud Medical City Saudi Arabia, Oman, United Arab Emirates 2020-04-01 2020-12-29 ISRCTN21363594, KSMC-IRB-H1R1-29-APR20-01 Phase 2 Clinical Recruiting 4 8 Months Dr Fahad Faqihi, Prof Karakitsos 2020-05-20
RICO: COVID-19 - Study of the Kinetics of the Immune Response During the Intensive Care Unit Stay in Adult Patients Infected With SARS-CoV-2: Multicentric, Non-Interventional Study Coronavirus disease 19 infection, Lung disease Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospices Civils De Lyon ACCRA France 2020-05-11 2021-02-28 2020-A01079-30, 69HCL20_0358, NCT04392401, RICO Phase Not Applicable Recruiting 7 9 Months 200 Anne-Claire LUKASZEWICZ, Pr, Bertrand SOUWEINE, Pr, Carole SCHWEBEL, Pr, Fabienne VENET, Guillaume THIERY, Pr, Hodane YONIS, MD, Laurent ARGAUD, Pr, Marie GROUSSAUD, Thomas RIMMELE, Pr, Vincent PIRIOU, Pr 2020-05-20
Effect of selenium on covid-19 disease Coronavirus disease 19 infection, Respiratory distress syndrome standard protocol treatment alone, hydroxychloroquine plus selenium Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ilam University of Medical Sciences Iran 2020-04-26 IR.MEDILAM.REC.1399.010, IRCT20190418043307N1 Phase 3 Clinical Recruiting 1 100 Ali Nazari, Elham Shafiei 2020-05-20
Evaluating Ehe Effects of Umifenovir (Arbidol) in COVID-19 Coronavirus disease 19 infection Arbidol alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shaheed Beheshti Medical University Iran 2020-04-08 IR.SBMU.RETECH.REC.1399.030, IRCT20151227025726N15 Phase 3 Clinical Recruiting 1 100 Afshin Zarghi, Ali Saffaei, Farzaneh Dastan, Payam Tabarsi 2020-05-20
A clinical study to assess TR-C 19 in the treatment of voluntary COVID-19 patients Coronavirus disease 19 infection TR-C 19 (COVID-19) VSY Biotechnology/Saglik Bilimleri Universitesi alone VSY Biotechnology Phase Not Applicable Not yet recruiting 0 2020-05-20
CTC REGISTRY: Registry of CytoSorb Therapy in COVID-19 ICU Patients Coronavirus disease 19 infection, Respiratory failure Continuous Renal Replacement Therapy (CRRT) alone, CytoSorb device alone, CytoSorb hemoadsorption alone, Extracorporeal Membrane Oxygenation (ECMO) alone, hemoperfusion extracorporeal circuits alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) CytoSorbents Corp 2020-05-31 2021-08-31 2020-001, CTC REGISTRY, FDA EUA, NCT04391920 Phase Not Applicable Not yet recruiting 0 15 Months 1000 Ola Ogunsakin, MD, Peter Nelson, MD 2020-05-20
PROCTOLOCK: Proctologic Practice and Covid-19 Coronavirus disease 19 infection Healthy volunteers accepted Societa Italiana di Chirurgia ColoRettale Katholieke Universiteit Leuven, Queen Mary University of London, The George Institute for Global Health, Universita' Degli Studi "Magna Graecia" Di Catanzaro, University of Pisa Italy 2020-04-15 2020-04-26 1, NCT04392245, PROCTOLOCK Phase Not Applicable Completed 1 1050 2020-05-20
Convalescent Plasma for the Treatment of Severe SARS-CoV-2 (COVID-19) Coronavirus disease 19 infection convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital San Vicente Fundación Clínica Cardiovid, Clínica Las Américas, Clínica León XIII, Clínica Rosario El Tesoro, Clínica Universitaria Bolivariana, Grupo de Inmunodeficiencias primarias Universidad de Antioquia, Hospital Pablo Tobon Uribe Colombia 2020-06-30 2021-12-31 002, NCT04391101 Phase 3 Clinical Not yet recruiting 1 18 Months 231 Fabian A Jaimes Barragan, Epidemiol, Oliver G Perilla Suarez, Hematologist, Oliver Perilla Suarez, Hematologist 2020-05-20
RECOVERY: Resting Energy Expenditure of the Coronavirus (COVID19) Patient in Reanimation Context Coronavirus disease 19 infection, Obesity indirect calorimetry alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Center D 'Arras France 2020-06-01 2020-12-31 2020-04, NCT04391686, RECOVERY Phase Not Applicable Not yet recruiting 1 7 Months 90 Kathleen Jacquez, MSc, vincent Florent, MD, PhD, vincent florent, MD, PhD 2020-05-20
A randomized, placebo-controlled trial to evaluate the effect of two formulations of anti-viral treatment in the reduction of number of COVID-19 patients requiring intensive care treatment Coronavirus disease 19 infection anti-viral treatment alone Senzer Ltd Phase Not Applicable Planned 0 2020-05-19
COVID19-LLC-MW: Observatory of Patients With Chronic Lymphocytic Leukemia / Lymphocytic Lymphoma or Waldenstrom Disease Infected With COVID-19 Chronic lymphocytic leukemia, Coronavirus disease 19 infection, Lymphoplasmacytic lymphoma Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) French Innovative Leukemia Organisation Institut de Cancerologie Strasbourg Europe France 2020-06-01 2022-12-31 COVID19-LLC-MW, FILO-COVID19_LLC-MW, NCT04391946 Phase Not Applicable Not yet recruiting 1 31 Months 50 Luc-Matthieu FORNECKER, Pr, Raoul HERBRECHT, Pr, Valérie ROUILLE 2020-05-19
Efficacy of Extract of of Zingiber Cinnamomum and Zataria multiflora in Covid-19 Disease Coronavirus disease 19 infection Zingiber, Cinnamon zeylanicum and Zataria multiflora extract (Armagan Salamat Zagros Yasuj Company) alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Yasouj University of Medical Sciences and Health Services Iran 2020-05-21 IR.YUMS.REC.1399.029, IRCT20081011001323N25 Phase 2/Phase 3 Clinical Not yet recruiting 1 80 Ali Mousavizadeh, Sadrollah Mehrabi 2020-05-19
A controlled clinical study to assess KB-109 added to supportive self-care (SSC) for outpatients who are positive for SARS-CoV-2 infection with mild-to-moderate COVID-19 Coronavirus disease 19 infection KB-109 alone, supportive self-care (SSC) alone Kaleido Biosciences Inc Phase Not Applicable Planned 0 50 2020-05-19
Evaluating the effect of intravenous N-acetylcysteine versus placebo in the treatment of patients with mild and moderate acute respiratory distress syndrome caused by COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome N-acetylcysteine alone, routine care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hamadan University of Medical Sciences Iran 2020-06-04 IR.UMSHA.REC.1399.153, IRCT20120215009014N355 Phase 2 Clinical Not yet recruiting 1 92 Dr Abbas Taher, Dr. Maryam Mehrpooya, Dr. Saeid Bashirian 2020-05-20
A Phase II Study of COVID-19 Convalescent Plasma in High Risk Patients With COVID-19 Infection Coronavirus disease 19 infection convalescent plasma alone Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) TriHealth US 2020-05-05 2020-12-31 20-045, NCT04392232 Phase 2 Clinical Recruiting 0 7 Months 100 Thomas E. Coyle, MD, William Judd, MBA, MHA(C.) 2020-05-20
Oral Manifestation of COVID-19 Patient: A Cross-Sectional Study on Egyptian Population Coronavirus disease 19 infection, Mouth ulcer Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cairo University Egypt 2020-05-30 2020-06-30 54678, NCT04391881 Phase Not Applicable Not yet recruiting 1 1 Month 500 Dina Mounir Elkady, Dina Mounir Elkady, Phd, Rawda Hisham Abdel aziz, Phd 2020-05-20
TMPRSS2: Mechanism of Covid 19 infection in Humans Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Asian Healthcare Foundation India 2020-05-11 COVID19TMPRSS2, CTRI/2020/05/024989, TMPRSS2 Phase Not Applicable Not yet recruiting 1 200 Dr D Nageshwar Reddy, Dr M Sasikala 2020-05-20
COVIDSPERM: Detection of SARS-CoV-2 in Semen of COVID-19 Positive Males Coronavirus disease 19 infection PCR alone Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Universitair Ziekenhuis Brussel Belgium 2020-05-12 2020-08-31 COVIDSPERM, COVIDSPERM, NCT04391829 Phase Not Applicable Not yet recruiting 1 3 Months 20 Michael De Brucker, MD PHD, Valerie Uvin, MD 2020-05-20
The Sungai Buloh Experience: A Retrospective Study in Olfactory and Taste Disturbance in COVID-19 Ageusia, Coronavirus disease 19 infection, Dysgeusia, Dysomia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hospital Sungai Buloh Malaysia 2020-06-01 2020-07-08 54938, NMRR-20-932-54938 Phase Not Applicable Not yet recruiting 2 1 Month Raudha Ezaty binti Ruslan 2020-05-20
Pregnancy with COVID-19 in Malaysia : A Case Series Coronavirus disease 19 infection Female Hospital Sungai Buloh Malaysia 2020-05-13 54904, NMRR-20-931-54904 Phase Not Applicable No longer recruiting 1 Dr Siti Hayati binti Mohd Nahwari 2020-05-20
Homeopathy in prevention of COVID-19 Coronavirus disease 19 infection Arsenicum album alone Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Council for Research in Homoeopathy India 2020-05-13 CTRI/2020/05/024986 Phase Not Applicable Not yet recruiting 1 10000 Dr Anil Khurana, Dr Debadatta Nayak, Dr Raj K Manchanda 2020-05-20
A controlled, multicenter clinical study to assess KB-109 added to supportive self-care (SSC) for outpatients who are positive for SARS-CoV-2 infection with mild-to-moderate COVID-19 Coronavirus disease 19 infection KB-109 alone, supportive self-care (SSC) alone Kaleido Biosciences Inc 2020-05-14 Phase Not Applicable Recruiting 0 350 2020-05-19
APDepCOVID19: Antenatal and postpartum depression among Malaysian women treated as covid-19 and its contributory factors Coronavirus disease 19 infection, Postnatal depression Female Hospital Sungai Buloh Malaysia 2020-05-20 2020-10-19 54717, APDepCOVID19, NMRR-20-917-54717 Phase Not Applicable Not yet recruiting 1 5 Months 77 Dr Norhana Binti Mohd Kasim 2020-05-20
Incidence of COVID-19 Test Conversion in Post-surgical Patients Coronavirus disease 19 infection, Lower respiratory tract infection polymerase chain reaction test alone, serology tests alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Northwell Health Inc US 2020-05-13 2020-07-31 IRB #20-0404, NCT04392323 Phase Not Applicable Recruiting 0 2 Months 500 Aaron Nizam, MD, Andrew W Menzin, MD, MBA, Bruce Farber, MD, Ernesto Molmenti, MD, PhD, MBA, James Crawford, MD, Jose Prince, MD, Matthew Weiss, MD, Michael Nimaroff, MD, MBA, Santiago Miyara, MD 2020-05-20
Validity of at Home Visual Acuity Measurements for Telemedicine During Corona Virus (COVID-19) Pandemic Coronavirus disease 19 infection, Glaucoma, Uveitis non invasive visual acuity testing alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Vanderbilt University Medical Center, US US 2020-05-15 2022-05-01 200826, NCT04391166 Phase Not Applicable Not yet recruiting 0 23 Months 150 Jeffery Kammer, MD, Megan C Barrett, CPO, Saige Wilkins, COA, Sapna Gangaputra, MD, MPH, Sean Donahue, MD, PHD, Shriji Patel, MD, Sylvia Groth, MD 2020-05-20
Efficacy and Safety of Itolizumab in COVID-19 Complications Coronavirus disease 19 infection antibiotics alone, antivirals alone, hydroxychloroquine alone, itolizumab alone, oxygen alone T-cell differentiation antigen CD6 inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Biocon Ltd India 2020-05-01 CTRI/2020/05/024959, ITOLI-C19-02-I-00 Phase 2 Clinical Recruiting 3 30 Dr Milind Nadkar, Dr Murli Mohan, Dr Shashank Joshi, Dr Subramanian Loganathan, Dr Suresh Kumar, Sivakumar Vaidyanathan 2020-05-20
Effect of intrapulmonary injection of processed serum derived from Covid-19 patients in reduction of pulmonary complications Coronavirus disease 19 infection autologous serum alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Tabriz University of Medical Sciences Iran 2019-05-05 IR.TBZMED.REC.1399.014, IRCT20091012002582N21 Phase 2 Clinical No longer recruiting 1 30 Ata Mahmoodpoor, Khosro Adibkia, Leila Roshangar 2020-05-20
IVIG and COVID19 Coronavirus disease 19 infection, Lung injury Flebogamma DIF 5% alone Beta amyloid modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Oroumia University of Medical Sciences Iran 2020-05-09 IR.UMSU.REC.1399.025, IRCT20200501047259N1 Phase 3 Clinical Recruiting 1 40 Naser Gharebaghi, Reza Hajizadeh 2020-05-20
A phase II, open design trial to evaluate KAND-567 in covid-19 patients Coronavirus disease 19 infection KAND-567 alone, best standard treatment alone CX3CR1 chemokine antagonist, Fractalkine ligand inhibitor Kancera AB Capio S:t Görans Hospital, Scandinavian CRO, Scandinavian Development Services AB, Science For Life Laboratory Sweden Phase 2 Clinical Planned 1 40 2020-05-19
Serial, cross-sectional, seroprevalence study of SARS-CoV-2 infection during and after the COVID-19 epidemic in Heidelberg and the Rhein-Neckar region Coronavirus disease 19 infection blood sampling alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Heidelberg SAP SE Germany 2020-05-25 DRKS00021709, S-279/2020 Phase Not Applicable Not yet recruiting 1 1500 Claudia Maria Denkinger 2020-05-20
Intervention Coronavirus disease 19 infection, Respiratory tract infection hyoscyamus niger methanolic extract plus propolis Kashan University of Medical Sciences and Health Services Iran 2020-05-06 IR.KAMUS.REC.1399.001, IRCT20200516047462N1 Phase 2 Clinical Recruiting 1 50 Dr. Hamidreza Banafsheh, Morteza Kosari 2020-05-20
Study to efficacy of Ivermectin in patients of COVID-19 Coronavirus disease 19 infection ivermectin alone, standard of care alone Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) RD Gardi Medical College India 2020-05-24 CTRI/2020/05/025224 Phase 2 Clinical Not yet recruiting 0 50 Dr Ashish Pathak, Dr Sunil Rathi 2020-05-20
COALA: Covid-19 related Obstetric Anesthesia Longitudinal Assessment-Registry Coronavirus disease 19 infection Female University Hospital Wurzburg Germany 2020-03-25 63/20-kr, COALA, DRKS00021772 Phase Not Applicable Recruiting 1 Magdalena Sitter, Peter Kranke 2020-05-20
Efficacy of Tablet AOIM - Z in Prevention of COVID - 19 in High Risk Healthy Police Personnel Coronavirus disease 19 infection AOIM - Z alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Shree Dhootapapeshwar Limited India 2020-06-01 CTRI/2020/05/025222 Phase 4 Clinical Not yet recruiting 0 275 Dr Mahesh Kumar Harit, Dr Vedvati Bhapkar, Dr Vinay Pawar 2020-05-20
SAPRIS-SERO: Health, Perception, Practices, Relations and Social Inequalities in the General Population During the Covid-19 Crisis Coronavirus disease 19 infection dried blood spot sampling alone Healthy volunteers accepted INSERM France 2020-05-01 2020-12-31 2020-A01195-34, C20-26, NCT04392388, SAPRIS-SERO Phase Not Applicable Recruiting 1 8 Months 110000 Fabrice Carrat, Fabrice Carrat, MD 2020-05-19
Create registry of Childhood Cancer patients in India with COVID 19 to provide guidelines for prevention and treatment Cancer, Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Max Super Speciality Hospital India 2020-05-26 CTRI/2020/05/025221, InPOG-EPI-20-02 Phase Not Applicable Not yet recruiting 0 1000 Dr Ramandeep Arora 2020-05-20
Neuropsychiatric effects of COVID-19 Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder Neuropsychiatric effects alone University Malaya Medical Centre Malaysia 2020-05-18 2021-05-18 54785, NMRR-20-905-54785 Phase Not Applicable Not yet recruiting 1 12 Months Dr Tai Mei Ling Sharon 2020-05-20
A study to evaluate anakinra in patients with severe coronavirus disease 2019 (COVID-19) with pneumonia and sHLH Coronavirus disease 19 infection, Hemophagocytic lymphohistiocytosis, Respiratory failure, Viral pneumonia antibiotics alone, anakinra plus hydroxychloroquine Type I IL-1 receptor antagonist Cell Press, Hellenic Institute for the Study of Sepsis Greece, Netherlands Phase 2 Clinical Status not specified 2 8 2020-05-19
COVID-19 Genome Sequence Coronavirus disease 19 infection Genome Sequencing alone The National Institute of Public Health Laboratory, Phnom Penh Malaysia 2020-05-12 2020-12-31 54809, NMRR-20-904-54809 Phase Not Applicable Status not specified 1 7 Months Dr NOORLIZA BINTI MOHAMAD NOORDIN 2020-05-20
PICP19: A clinical trial for validating therapeutic efficacy of convalescent plasma in severe COVID-19 disease Coronavirus disease 19 infection convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Council of Scientific and Industrial Research (India) India 2020-05-20 CTRI/2020/05/025209, PICP19 Phase 2 Clinical Not yet recruiting 1 80 Dipyaman Ganguly, Dr Biswanath Sharma Sarkar, Yogiraj Ray 2020-05-20
Arsenicum album-30c as prophylactic for COVID-19 Coronavirus disease 19 infection arsenicum album-30c alone Healthy volunteers accepted, Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Council for Research in Homoeopathy India 2020-05-24 CTRI/2020/05/025205 Phase 2/Phase 3 Clinical Not yet recruiting 10 33000 Dr Anil Khurana, Dr Ashish Mahajan, Dr Ch Ravender, Dr Debadatta Nayak, Dr KC Murleedharan, Dr Karthikeyan, Dr Lipipushpa Debata, Dr P Hima Bindu, Dr P P Pal, Dr Ramesh Bawaskar, Dr Subhash Kaushik 2020-05-20
Evaluation of the Immuno-Stimulatory Potential (Shareera Bala) of an Ayurveda Management Protocol in Cohort of Quarantined Delhi Police under Covid-19 Care Centers- An Exploratory Clinical Study Coronavirus disease 19 infection Anu taila alone, Variable regimens including Herbal tea , Samshamani Vati , aridra khanda Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) All India Institute of Ayurveda India 2020-05-18 CTRI/2020/05/025178 Phase 2 Clinical Not yet recruiting 1 140 Dr VG Huddar, PIprof Dr Tanuja Nesari 2020-05-20
PHOBIC: Mental status of public during lockdown COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Siddha Central Research Institute India 2020-05-22 CTRI/2020/05/025194, PHOBIC Phase Not Applicable Not yet recruiting 1 280 Narrain shree S, Vinoth N P 2020-05-20
PSY: COVID-19: Psychological Impact of COVID-19 Pandemic Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sri Ramachandra Institute of Higher Education and Research United Arab Emirates, India, US 2020-05-19 CTRI/2020/05/025184, PSY: COVID-19 Phase Not Applicable Not yet recruiting 2 1000 Dr Vivian Kapil V 2020-05-20
COVID-19 Long QT: COVID-19 Long QT Coronavirus disease 19 infection azithromycin alone, chloroquine alone, hydroxychloroquine alone, lopinavir + ritonavir alone, smartphone ECG monitoring alone, Variable regimens including azithromycin , chloroquine , hydroxychloroquine , lopinavir + ritonavir HIV protease inhibitor Sarawak Heart Centre Malaysia 2020-05-18 2020-05-19 54921, COVID-19 Long QT, NMRR-20-975-54921 Phase Not Applicable Recruiting 1 30 Dr Koh Keng Tat 2020-05-20
Clinical trial to assess the prognostic repercussions of rosuvastatin treatment in patients discharged after hospitalization for COVID-19 Positive Cardiac failure, Coronavirus disease 19 infection, Deep vein thrombosis, Lung embolism, Myocardial infarction rosuvastatin alone HMG CoA reductase inhibitor Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto de Investigación Sanitaria de la Fundacion Jimenez Diaz Jimenez Diaz Foundation Spain 2020-05-14 2020-001319-26, FJD-COVID-ESTATINAS Phase 3 Clinical Recruiting 1 1080 CLINICAL RESEARCH UNIT 2020-05-20
SEN-CoV-Fadj: Efficacy and Safety Evaluation of Treatment Regimens in Adult COVID-19 Patients in Senegal Coronavirus disease 19 infection azithromycin plus hydroxychloroquine Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institut Pasteur de Dakar Dalal Jamm Hospital, Senegal, Diamniadio Children Hospital, Senegal, Epicentre (MSF), Fann Hospital, Senegal, Ministry of Health, senegal Senegal 2020-06-01 2021-06-01 2020-002, NCT04390594, SEN-CoV-Fadj Phase 3 Clinical Not yet recruiting 3 12 Months 258 Abdoul Kane, MD, Aissatou Lakhe, MD, Amadou A. Sall, PhD, Fabien Taieb, MD, PhD, Fatou SD Ndiaye, MD, Khardiata D. Mbaye, MD, Louise Fortes, MD, Maguette N. Fall, MD, Moussa Seydi, MD, Oumar Kane, MD, Pape S. Ba, MD 2020-05-20
Postpartum Sexual Function in Pregnant Women With COVID-19 Coronavirus disease 19 infection, Dyspareunia, Female sexual dysfunction Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Istanbul Bakirkoy Maternity and Children Diseases Hospital Turkey 2020-05-14 2020-08-03 MTALMACCAROL, NCT04389489 Phase Not Applicable Not yet recruiting 1 2 Months 140 Merve Aldikactioglu Talmac, Merve Aldikactioglu Talmac, M.D. 2020-05-19
Respiratory Decompensation and Model for the Triage of COVID-19 Patients Coronavirus disease 19 infection, Respiratory disease COViage alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dascena US 2020-03-24 2020-05-30 051420, NCT04390516 Phase Not Applicable No longer recruiting 0 2 Months 197 2020-05-18
Front liner children in Covid-19 Coronavirus disease 19 infection Selayang Hospital Malaysia 2020-05-01 2020-05-15 54970, NMRR-20-908-54970 Phase Not Applicable Completed 1 Dr Tang Swee Ping 2020-05-18
LB-1148 for Pulmonary Dysfunction Associated With COVID-19 Pneumonia Coronavirus disease 19 infection, Lung inflammation, Respiratory disease, Viral pneumonia tranexamic acid (oral, multiple organ failure), InflammaGen/University of California San Diego alone Serine protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Leading BioSciences Inc 2020-06-30 2021-03-31 LBS-COVID19-201, NCT04390217 Phase 2 Clinical Not yet recruiting 0 9 Months 120 Brian K Wenzel, MS, CCRA, Inge K Bear, MS, CCRA, Michael J Dawson, MD 2020-05-18
Post-operative Recovery Index, Patient Expectations and Satisfaction With Prenatal Care Instrument in Pregnant Patients With COVID-19 Coronavirus disease 19 infection optimum postoperative care alone Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Istanbul Bakirkoy Maternity and Children Diseases Hospital Turkey 2020-05-14 2020-08-03 MTALMAC3, NCT04389515 Phase Not Applicable Not yet recruiting 1 2 Months 75 Merve Aldikactioglu Talmac 2020-05-19
TOFACoV-2: Tofacitinib Plus Hydroxychloroquine versus Hydroxychloroquine in Patients With COVID-19 Interstitial Pneumonia Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia hydroxychloroquine plus tofacitinib citrate (oral, inflammation), Pfizer JAK tyrosine kinase inhibitor, Jak1 tyrosine kinase inhibitor, Jak3 tyrosine kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Universita Politecnica delle Marche ASST Cremona, ASST Papa Giovanni XXIII, Azienda Ospedaliera Ospedali Riuniti Marche Nord, Azienda Policlinico Umberto I, Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico, Ospedale Civile Santo Spirito, Ospedale di Circolo e Fondazione Macchi, Università Magna Grecia Italy 2020-06-30 2020-10-31 2020-002035-30, NCT04390061, TOFACoV-2 Phase 2 Clinical Not yet recruiting 1 4 Months 116 Armando Gabrielli, Armando Gabrielli, MD 2020-05-20
The impact of Program Kesihatan Optimum (Pohon Sihat) on COVID-19 patients during COVID-19 pandemic Coronavirus disease 19 infection Program Kesihatan Optimum alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Putrajaya Hospital Malaysia 2020-05-18 2020-08-31 54998, NMRR-20-941-54998 Phase Not Applicable Not yet recruiting 1 3 Months Dr Thong Kai Shin 2020-05-19
DPCPM: Disease Progression of COVID-19 Patients in Malaysia Coronavirus disease 19 infection Government of Malaysia Malaysia 2020-05-15 2022-04-30 54834, DPCPM, NMRR-20-945-54834 Phase Not Applicable Not yet recruiting 2 23 Months Devi Peramalah, Dr. Noran Naqiah Hairi 2020-05-19
COVID-19 in the Swedish ICU-cohort: Risk Factors of Critical Care Admission and Intensive Care Mortality Coronavirus disease 19 infection, Diabetes mellitus, Hypertension ACE-inhibitors therapy alone, immunosuppressant therapy alone, intensive care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Uppsala University Center for Clinical Research Dalarna Sweden 2020-06-30 2020-06-30 NCT04390074, UTN: U1111-1251-8195 Phase Not Applicable Not yet recruiting 1 10000 Björn Ahlström, MD, Miklos Lipcsey, PhD 2020-05-20
Correlates between knowledge of COVID 19 and practice among patients in Luyang primary health clinic Coronavirus disease 19 infection KLINIK KESIHATAN LUYANG Malaysia 2020-05-15 2020-06-15 54915, NMRR-20-947-54915 Phase Not Applicable Not yet recruiting 1 1 Month Dr Nurul Akmanidar binti Zainuddin, Dr. Lee Wai Khew 2020-05-19
The Impact and Coping Strategy of COVID-19 Among Taiwan Society and Medical and Nursing Institutes Coronavirus disease 19 infection coping protocol plan alone, standardized crisis management alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kaohsiung Kai-Suan Psychiatric Hospital Taiwan 2020-06-01 2023-07-31 KSPH-2020-03, NCT04389476 Phase Not Applicable Not yet recruiting 1 38 Months 2500 Frank Huang-Chih Chou 2020-05-19
PROTECT: Prophylaxis for patients at risk of COVID-19 infection Coronavirus disease 19 infection hydroxychloroquine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cambridge University Hospitals NHS Foundation Trust University of Cambridge UK 2020-05-31 2025-08-31 A095590, NCT04389359, PROTECT Phase 2/Phase 3 Clinical Not yet recruiting 1 63 Months 1500 Kerrie Brusby, PhD, Thomas Hiemstra, PhD 2020-05-18
SEIR models to determine the effectiveness of the Movement Control Order (MCO) during the COVID-19 pandemic in Malaysia Coronavirus disease 19 infection movement control order (MCO) alone Institute For Medical Research (Inc In Malaysia) Malaysia 2020-05-22 2020-12-31 54856, NMRR-20-953-54856 Phase Not Applicable Status not specified 1 7 Months Dr Sarbhan Singh a/l Lakha Singh, Pharmacist Law Kian Boon 2020-05-20
miR-AGE: A phase IIb/III, randomized, double-blind and placebo-controlled clinical trial of ABX-464 in Covid-19 patients Coronavirus disease 19 infection ABX-464 alone, standard of care alone Rev protein modulator Abivax SA Bpifrance Europe, France miR-AGE Phase 2/Phase 3 Clinical Not yet recruiting 1 1034 Eric Cua 2020-05-20
Safety and Efficacy of Intravenous Wharton's Jelly Derived Mesenchymal Stem Cells in Acute Respiratory Distress Syndrome Due to COVID 19 Coronavirus disease 19 infection, Respiratory distress syndrome ventilation support therapy alone, Variable regimens including Wharton's jelly derived mesenchymal stem cells , azithromycin , hydroxychloroquine , lopinavir + ritonavir HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) BioXcellerator Clinical Somer Colombia 2020-06-30 2021-05-31 BIOXSOMCOV001, NCT04390152 Phase 1/Phase 2 Clinical Not yet recruiting 1 11 Months 40 Alfredo Hernandez-Ruiz, MSc, Santiago Saldarriaga-Gomez, MSc 2020-05-20
Phase II/III, randomized, blinded, placebo-controlled, multicenter trial of emetine in high-risk, symptomatic adult COVID-19 patients not requiring hospitalization Coronavirus disease 19 infection emetine alone Acer Therapeutics Inc 2020-09-30 Phase 2/Phase 3 Clinical Planned 0 2020-05-19
To observe the effect of Ayurvedic medicine for the treatment of COVID-19 Coronavirus disease 19 infection AYUSH 64 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Central Council for Research in Ayurvedic Sciences India 2020-05-24 CTRI/2020/05/025214 Phase 2/Phase 3 Clinical Not yet recruiting 1 Dr Sumit Shrivastva 2020-05-18
Ayurveda formulation for COVID-19 prevention Coronavirus disease 19 infection Guduchi ghan vati alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Central Council for Research in Ayurvedic Sciences India 2020-05-23 CTRI/2020/05/025213 Phase Not Applicable Not yet recruiting 1 1500 Dr Kavita Vyas 2020-05-19
Immunogenetics Predictors With COVID-19 Coronavirus disease 19 infection genotyping alone, real-time polymerase chain reaction alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mansoura University Egypt 2020-05-10 2022-05-09 NCT04390269, R.20.05.830.R1 Phase Not Applicable Not yet recruiting 1 24 Months 200 Mahmoud El-Bendary, M.D 2020-05-19
Combination: Combination Therapy With Isotretinoin and Tamoxifen May Provide Complete Protection Against Severe Acute Respiratory Syndrome Coronavirus Coronavirus disease 19 infection, Respiratory failure Variable regimens including isotretinoin , isotretinoin (aerosolized) , tamoxifen Estrogen receptor antagonist, Retinoic acid receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Kafrelsheikh University Egypt 2020-05-31 2020-08-31 COV-19 TREATMENT THIS IS, Combination, NCT04389580 Phase 2 Clinical Not yet recruiting 1 3 Months 160 M.Sc.Mahmoud Elkazzaz, M.Sc.Biochemistry, Mahmoud Ramadan mohamed Elkazzaz 2020-05-20
PCHF-COVICAV: The Global PCHF-COVICAV Registry Acute coronary syndrome, Arterial hypertension, Cardiac arrest, Cardiac failure, Cardiovascular disease, Coronavirus disease 19 infection, Diabetes mellitus, Heart arrhythmia, Lipid metabolism disorder, Myocarditis echocardiography alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Zurich Wroclaw Medical University Switzerland 2020-04-30 2021-07-31 NCT04390555, PCHF-COVICAV, PCHF-COVICAV Phase Not Applicable Recruiting 1 15 Months 1500 Andreas Flammer, PD Dr. med, Frank Ruschitzka, Prof. Dr. med, Mateusz Sokolski, MD, PhD, Sander Trenson, MD 2020-05-18
The Safety and Preliminary Efficacy of Lucinactant in Adults With COVID-19 Acute lung injury, Coronavirus disease 19 infection lucinactant (liquid instillate), Windtree Therapeutics/ Esteve/ Lee's Pharmaceutical alone Bone morphogenetic protein-10 ligand inhibitor, Bone morphogenetic protein-15 ligand inhibitor, Lung surfactant associated protein B stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Windtree Therapeutics Inc US 2020-06-01 2020-11-30 02-CL-2001A, NCT04389671 Phase 1/Phase 2 Clinical Not yet recruiting 0 6 Months 30 Phillip D Simmons, MS, Steven G Simonson, MD, Steven Keller, MD, PhD, Yuh-Chin T Huang, MD, MHS 2020-05-18
Convalescent Plasma for the Treatment of COVID-19 Coronavirus disease 19 infection, Multiple organ failure, Respiratory failure, Septic shock ABO compatible COVID-19 convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Thomas Jefferson University US 2020-04-15 2021-04-14 20D.379, NCT04389710 Phase 2 Clinical Recruiting 0 12 Months 100 Anna Marie Chang, MD, Michael Baram, MD 2020-05-18
PAP-COVID: Early CPAP in COVID-19 Confirmed or Suspected Patients Coronavirus disease 19 infection, Respiratory disease, Viral pneumonia WatchPAT alone, continuous positive airway pressure therapy alone, pulse oximeter monitoring alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mount Sinai School of Medicine Community Surgical Supply of Toms River, Inc, Itamar Medical (Cm) 1997 Ltd, Philips Healthcare USA US 2020-05-07 2021-05-31 GCO 20-0900, NCT04390191, PAP-COVID Phase Not Applicable Recruiting 0 12 Months 200 Neomi Shah, MD, MPH, MS, Samira Khan, MPH 2020-05-20
Feasibility of Non-contact Magnetically-controlled Capsule Endoscopy During COVID-19 Pandemic Coronavirus disease 19 infection MCE system, Ankon Technologies alone, non-contact magnetically-controlled capsule endoscopy alone, simethicone alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Changhai Hospital China 2020-03-26 2020-05-20 NC-MCE PILOTRCT, NCT04389333 Phase 2 Clinical Recruiting 1 1 Month 40 Jiahui Zhu, MD, Zhuan Liao, Zhuan Liao, MD 2020-05-18
A study to evaluate the effect of Oral Niclosamide in mild and very mild COVID-19 cases Coronavirus disease 19 infection niclosamide alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Lady Hardinge Medical College India 2020-05-15 CTRI/2020/04/024949 Phase 2 Clinical Not yet recruiting 1 48 Anupam Prakash 2020-05-18
CSTC-Exo: COVID-19 Specific T Cell Derived Exosomes Coronavirus disease 19 infection, Viral pneumonia COVID-19 specific T cell derived exosomes alone, metered dose inhaler therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) TC Erciyes University Turkey 2020-05-01 2021-05-31 CSTC-Exo, ERUCOVID2020, NCT04389385 Phase 1/Phase 2 Clinical No longer recruiting 1 13 Months 60 Mustafa Cetin, Prof 2020-05-20
Ayurveda protocol and COVID-19 exposed individuals: Clinical trial of an Ayurveda Intervention Coronavirus disease 19 infection Ayurveda management protocol alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) All India Institute of Ayurveda 2020-05-16 CTRI/2020/05/025171 Phase 2 Clinical Not yet recruiting 0 50000 Dr Mahesh Vyas, Dr VG Huddar, Prof Dr Tanuja Nesari 2020-05-19
TACTIC-R: Multi-arm, Therapeutic Study In Pre-ICU Patients Admitted With COVID-19 - Repurposed Drugs Coronavirus disease 19 infection baricitinib alone, ravulizumab alone, standard of care alone Complement C5 factor inhibitor, IgG receptor FcRn large subunit p51 modulator, Jak1 tyrosine kinase inhibitor, Jak2 tyrosine kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cambridge University Hospitals NHS Foundation Trust Alexion Pharmaceuticals Inc, Eli Lilly & Co Ltd UK 2020-05-01 2022-05-01 2020-001354-22, CCTU0303, IRAS 282213, ISRCTN11188345, NCT04390464, TACTIC-R, TACTIC-R Phase 4 Clinical Recruiting 3 24 Months 1167 Dr Joseph Cheriyan, Elena Hernan Sanch0, Elena Hernan-Sancho, Frances Hall Hall, FRCP (UK), D.Phil, Maria King 2020-05-19
Evaluation of the effect of Tocilizumab on outcomes of the severe COVID-19 patients Coronavirus disease 19 infection tocilizumab alone Arak University of Medical Sciences and Health Services Iran 2020-05-21 IR.ARAKMU.REC.1399.030, IRCT20200510047383N1 Phase 3 Clinical Not yet recruiting 1 100 Dr. Mohammadreza Bozorgmanesh, Zahrasadat Mousavi, ِDr. Mohammadreza Bozorgmanesh 2020-05-20
A clinical Trial to Study the Effects of Hydroxychloroquine, Ciclesonide and Ivermectin in treatment of moderate COVID-19 illness Coronavirus disease 19 infection ciclesonide alone, hydroxychloroquine alone, ivermectin alone Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Lady Hardinge Medical College India 2020-05-15 CTRI/2020/04/024948 Phase 2 Clinical Not yet recruiting 1 120 Anupam Prakash 2020-05-19
Evaluation of Efficacy and Safety of Thymoquinone compared to Best supportive care in Patients with COVID-19 Coronavirus disease 19 infection Best supportive care alone, Thymoquinone alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Intas Pharmaceuticals Ltd India 2020-05-17 0248-20, Version No: 2.0, CTRI/2020/05/025167 Phase 2 Clinical Recruiting 2 64 Dr Dhaiwat Shukla, Dr Janak Khambhoja, Dr Naman Shah, Mr Prashant Modi 2020-05-19
Study of ASHWAGANDHA TABLET on healthy individuals to prevent covid-19 Coronavirus disease 19 infection Ashwagandha tablet alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ministry of Ayush India 2020-05-19 CTRI/2020/05/025166 Phase 2 Clinical Not yet recruiting 1 1200 Dr C Muralikrishna 2020-05-19
Patient Outcome of Cardiac Surgery During the COVID-19 Pandemic Coronavirus disease 19 infection, Surgical procedure cardiac surgery alone, thoracic surgery alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) CHU De Nantes France 2020-05-11 2022-06-30 HEART-19 STUDY, NCT04389463 Phase Not Applicable Recruiting 1 25 Months 350 Annick COULON, Mickael VOURC'H, MD 2020-05-19
Use of Desferal for Prevention of ARDS in Hospitalized Cases Documented With Covid 19 Infection Coronavirus disease 19 infection, Respiratory distress syndrome deferoxamine mesylate alone Cairo University Egypt 2020-06-01 2020-12-31 0012, NCT04389801 Phase 4 Clinical Not yet recruiting 1 7 Months 200 Hesham Al-Inany 2020-05-19
CLEO-CD: COVID-19 Related Lockdown Effects On Chronic Diseases Age related macular degeneration, Cardiac failure, Coronary artery disease, Coronavirus disease 19 infection, Hematological neoplasm, Hemophilia, Idiopathic pulmonary fibrosis, Macular edema, Multiple sclerosis, Myocardial infarction, Pulmonary artery hypertension, Respiratory failure, Temporal arteritis Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire Dijon France 2020-04-20 2021-11-07 BOULIN AOIC 2020, CLEO-CD, NCT04390126 Phase Not Applicable No longer recruiting 1 18 Months 1200 2020-05-20
Convalescent Plasma for COVID-19 Close Contacts Coronavirus disease 19 infection convalescent plasma alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Columbia University US 2020-05-31 2021-04-30 AAAT0052, NCT04390503 Phase 2 Clinical Recruiting 0 11 Months 200 Jennifer Zech, MSc, Jessica Justman, MD 2020-05-20
Epidemiological, clinical and prognosticated features of novel coronavirus pneumonia (COVID-19) in Zhuhai Coronavirus disease 19 infection, Viral pneumonia Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fifth Affiliated Hospital, Sun Yat-Sen University China 2020-04-01 2021-04-01 ChiCTR2000032895 Phase Not Applicable Recruiting 1 12 Months 100 Jing Liu 2020-05-19
D-dimer Levels in Pregnant With COVID-19 Coronavirus disease 19 infection ELISA test alone Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Istanbul Bakirkoy Maternity and Children Diseases Hospital Turkey 2020-05-14 2020-07-03 MTALMAC, NCT04389554 Phase Not Applicable Recruiting 1 1 Month 400 Merve Aldikactioglu Talmac 2020-05-19
Interferon Gamma Induced Protein 10 (IP-10) in a Clinical Decision Support Protocol in COVID-19 Patients Coronavirus disease 19 infection clinical decision support protocol alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) MeMed Diagnostics Ltd Israel 2020-04-07 2020-05-12 MM-5000-BV, NCT04389645 Phase Not Applicable Completed 1 1 Month 52 Shaul Lev, MD 2020-05-19
The duration and influencing factors of medical staff wearing disposable protective equipment in the isolation area during novel coronavirus pneumonia (COVID-19): an epidemiological study Coronavirus disease 19 infection, Viral pneumonia The First Affiliated Hospital of Dalian Medical University China 2020-03-16 2020-04-01 ChiCTR2000032884 Phase Not Applicable No longer recruiting 1 176 Li Fanglin, Shi Tieying 2020-05-18
Double-Blind, Multicenter, Study to Evaluate the Efficacy of PLX-PAD for the Treatment of COVID-19 Adult respiratory distress syndrome, Coronavirus disease 19 infection PLX stem cell therapy, Pluristem/Cha Bio & Diostech alone IL-6 receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Pluristem Ltd Israel, US 2020-05-31 2021-09-30 NCT04389450, PLX-COV-01 Phase 2 Clinical Not yet recruiting 1 16 Months 140 Ami Mayo, MD, Paul Sanders, MD 2020-05-19
International survey to investigate the implementation of ICU daily care for COVID-19 Coronavirus disease 19 infection Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Japanese Society of Intensive Care Medicine Australia, South America, Asia, North America, Japan, Europe, Africa 2020-05-18 UMIN000040405 Phase Not Applicable Not yet recruiting 2 200 Keibun Liu, Tomoko Nakayasu 2020-05-19
Novel coronavirus pneumonia (COVID-19) s-vax loaded autologous dendritic cell trial Coronavirus disease 19 infection COVID-19 s-vax loaded autologous dendritic cells alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Beijing Tiers Cell Technology Co., Ltd China 2020-05-01 2022-04-30 ChiCTR2000033003 Phase 0 Clinical Not yet recruiting 0 24 Months 25 Xiaoyu Xiang 2020-05-20
HSS Covid-19 Antibody Serology Among Surgeons and Anesthesiologists Coronavirus disease 19 infection SARS-CoV2 serum antibody test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital for Special Surgery NY US 2020-05-05 2020-10-30 2020-0850, NCT04389294 Phase Not Applicable Recruiting 0 5 Months 300 Alexander P Hughes, MD, Ellen M Soffin, MD, PhD 2020-05-19
Efficacy evaluation of inhalation therapy (nasal spray) of Interferon Beta-1a in Mild to Moderate cases of Covid-19 at Baqiyatallal Hospital Coronavirus disease 19 infection national corona treatment alone, hydroxychloroquine plus interferon beta 1a CinnaGen Co Iran 2020-05-21 IR.BMSU.REC.1399.122, IRCT20200511047396N1 Phase 3 Clinical Not yet recruiting 1 100 Ashraf Karbasi 2020-05-20
The effect of cognitive-behavioral intervention on improving COVID-19 fear symptoms, improving quality of life and improving mental health in patients with corona Coronavirus disease 19 infection, Psychiatric disorder cognitive-behavioral crisis intervention alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Tehran University of Medical Sciences Iran 2020-05-03 IR.TUMS.VCR.REC.1399.335, IRCT20200509047360N1 Phase Not Applicable Recruiting 1 60 Seyyed Salman Alavi 2020-05-20
Evaluation of the effect of GCSF injection in treatment of COVID-19 patients with lymphopenia Coronavirus disease 19 infection, Lymphocytopenia, Viral pneumonia Granulocyte colony-stimulating factor (GCSF) alone Semnan University of Medical Sciences Iran 2020-05-21 IR.SEMUMS.REC.1399. 13, IRCT20200502047268N1 Phase 1/Phase 2 Clinical Not yet recruiting 1 10 Akram Alizadeh, Amir Sarabi, Amir sarabi 2020-05-20
Evaluation of the efficiency and safety of favipiravir + hydroxychloroquine drug regimen in comparison with hydroxychloroquine in hospitalized patients with covid-19 Coronavirus disease 19 infection antibiotic therapy alone, Variable regimens including favipiravir , hydroxychloroquine , oxygen RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shaheed Beheshti Medical University Iran 2020-05-19 IR.SBMU.RETECH.REC.1399.053, IRCT20200428047228N1 Phase 3 Clinical Recruiting 1 50 Dr. Mohammad Fathi, ِDr.Mohammad Fathi 2020-05-20
A clinical study of imatinib for the treatment in patients with COVID-19-associated ARDS Adult respiratory distress syndrome, Coronavirus disease 19 infection imatinib alone Abl tyrosine kinase inhibitor, Bcr protein inhibitor, Kit tyrosine kinase inhibitor, PDGF receptor antagonist, Signal transduction inhibitor Exvastat Ltd Innovative Medicines Initiative Phase Not Applicable Planned 0 110 2020-05-18
Study to Evaluate the Effect of a Probiotic in COVID-19 Coronavirus disease 19 infection probiotic alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bioithas SL Spain 2020-05-04 2021-05-31 COVID.PROB, NCT04390477 Phase Not Applicable Recruiting 2 12 Months 40 Laura Navarro, Maria Isabel Perez-Soto, Maykel Ayo-González, Vicente Navarro 2020-05-19
A COVID-19 antibody case study to help guide health preservation protocols and public discourse about the pandemic Coronavirus disease 19 infection Progressive Care Inc US Phase Not Applicable Planned 0 2020-05-18
Famotidine Outpatient COVID-19 Treatment Study Coronavirus disease 19 infection famotidine alone Histamine H2 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Northwell Health Inc Cold Spring Harbor Laboratory US 2020-05-12 2020-05-20 1605914-1, NCT04389567 Phase Not Applicable No longer recruiting 0 10 David A Tuveson, MD PhD 2020-05-19
Antimalarial and COVID-19 in Rheumatoid Arthritis Coronavirus disease 19 infection, Rheumatoid arthritis hydroxychloroquine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Assiut University Egypt 2020-03-15 2020-05-01 COVID 19 IN RA, NCT04389320 Phase Not Applicable Completed 1 1 Month 60 Manal Hassanien 2020-05-19
CONDITION: Contagiousness and Immunogenicity Status of COVID-19 in Asymptomatic Population (COVID-19 CONDITION) Coronavirus disease 19 infection ELISA test alone, polymerase chain reaction (PCR) test alone Healthy volunteers accepted Igenomix Spain Spain 2020-05-07 2020-08-31 CONDITION, IGX1-COV-XS-20-01, NCT04389658 Phase Not Applicable Recruiting 1 3 Months 1000 Carlos Gomez, BSc MSc, Carlos Gomez, Bsc, MSc, Carlos Simon, MD PhD, Carlos Simon, MD,PhD, Nasser Al-Asmar, BSc PhD, Xavier Santamaria, MD PhD, Xavier Santamaria, MD, PhD, Xavier Santamaria, MD,PhD 2020-05-19
COPICADS: COVID-19 Pandemic Impact on Patients With Cancer - a Danish Survey Cancer, Coronavirus disease 19 infection cancer treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Odense University Hospital Denmark 2020-05-14 2023-05-01 COPICADS, NCT04389996, OP_1132 Phase Not Applicable Recruiting 1 35 Months 5000 Stefan S Jeppesen, MD, PhD, Stefan Starup Jeppesen 2020-05-20
Dociparstat for the Treatment of Severe COVID-19 in Adults at High Risk of Respiratory Failure Acute lung injury, Coronavirus disease 19 infection, Respiratory failure dociparstat (iv, AML/acute lung injury/COVID-19), Chimerix alone CXCR4 chemokine modulator, Cathepsin G inhibitor, Complement cascade inhibitor, Elastase inhibitor, Heparin agonist, High mobility group protein B1 inhibitor, L selectin antagonist, P selectin antagonist, Platelet factor 4 ligand inhibitor, Stromal cell-derived factor 1 ligand modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chimerix Inc US 2020-05-31 2021-03-31 CMX-DS-004, NCT04389840 Phase 2/Phase 3 Clinical Recruiting 0 10 Months 524 Elizabeth MacLeod, Marion Morrison, MD 2020-05-20
COVIDICA: Clinical and Psycho-social Impact of COVID-19 Related Confinement on Patients With Digestive Tumors Coronavirus disease 19 infection, Gastrointestinal tumor, Metastatic colorectal cancer, Metastatic pancreas cancer Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire De Poitiers Etablissement D’Hospitalisation France 2020-05-15 2021-05-15 2020-A01301-38, COVIDICA, NCT04389684 Phase Not Applicable Not yet recruiting 1 12 Months 120 Violaine RANDRIAN, PhD 2020-05-19
COSMO: The COVID-19 Symptom Montelukast Trial Coronavirus disease 19 infection, Respiratory distress syndrome montelukast sodium alone Leukotriene D4 antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) McGill University Lady Davis Institute Canada 2020-07-31 2021-06-30 443807, COSMO, NCT04389411 Phase 2/Phase 3 Clinical Not yet recruiting 1 11 Months 600 Geoffrey Tranmer, PhD, Machelle Wilchesky, Machelle Wilchesky, PhD 2020-05-19
COVID-LAN: Lanadelumab for treatment of COVID-19 disease Coronavirus disease 19 infection lanadelumab alone Plasma kallikrein inhibitor Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Radboud University Medical Center Nijmegen Netherlands 2020-002472-12, COVID-LAN, UMCN-AKF20.04 Phase 4 Clinical Recruiting 1 80 Roger Bruggemann 2020-05-18
Convalescent Plasma as Treatment for Acute Coronavirus Disease (COVID-19) Coronavirus disease 19 infection SARS-CoV-2 convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Karolinska University Hospital Danderyd Hospital, Karolinska Institutet Sweden 2020-04-10 2020-12-31 CP1, NCT04390178 Phase 1/Phase 2 Clinical No longer recruiting 2 8 Months 10 Johan Ursing, MD, PhD 2020-05-19
CoBRA: CoViD-19 imaging register study Aachen Coronavirus disease 19 infection CoViD-19 imaging alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Aachen Germany 2020-04-05 097/20, CoBRA, DRKS00021740 Phase Not Applicable Recruiting 1 100 Christiane Kuhl 2020-05-20
ILIAD 7: Recombinant InterLeukin-7 (CYT-107) to Improve clinical outcomes in lymphopenic pAtients with COVID-19 infection Coronavirus disease 19 infection CYT-107 alone IL-7 receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) RevImmune SAS France Spain, Belgium, US, Italy, France 2020-05-06 2020-001786-36, ILIAD 7, ILIAD-7-UK-Cohort Phase 2 Clinical Recruiting 4 Michel Morre 2020-05-19
Clinical Effects of Internet Assisted Pulmonary Rehabilitation of COVID-2019 Pneumonia Patients After Discharge Coronavirus disease 19 infection, Viral pneumonia pulmonary rehabilitation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) China-Japan Friendship Hospital Ai You Foundation, Wuhan Central Hospital, Wuhan Tuberculosis Prevetion And Cure Hosptial, Wuhan University China 2020-04-06 2020-10-30 2020-22-K17, NCT04368793 Phase Not Applicable Recruiting 3 6 Months 300 Geyi Wen, Resident, Guangyun Guo, Doctor, Hongtao Niu, Ting Yang, Doctor, Yi Hu, Doctor, Zhenshun Cheng, Doctor 2020-05-19
Malaysian COVID-19 Anosmia Study (Phase I) - A Nation-wide, Multicenter, Cross-Sectional Study Coronavirus disease 19 infection, Dysomia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sultanah Bahiyah Hospital HOSPITAL RAJA PEREMPUAN ZAINAB II, Hospital Enche' Besar Hajjah Khalsom, Hospital Melaka, Hospital Permai, Hospital Queen Elizabeth, Hospital Raja Permaisuri Bainun, Hospital Sultan Ismail, Hospital Sultanah Aminah Johor Bahru, Hospital Sultanah Maliha, Hospital Sultanah Nur Zahirah, Hospital Sungai Buloh, Hospital Tengku Ampuan Afzan, Hospital Tuanku Fauziah, Kuala Lumpur Hospital, Pulau Pinang Hospital, Sarawak General Hospital, Tuanku Jaafar Hospital Malaysia 2020-05-31 2020-08-31 MCO-001, MCO-002 54803, NCT04390165, NMRR-20-934-54803 Phase 1 Clinical Not yet recruiting 18 3 Months 760 Amran Mohamad, MD MS, Anilawati Mat Jelani, MD MMed, Chee Loon Leong, MBBS MMed, Chenthilnathan Periasamy, MBBS MMed, Chun Yiing Wong, MBBS MMed, Dzawani Muhamad, MD MMed, Elang Kumaran Krishnan, MBBS MS, Fadzilah Ismail, MD MS, Halimuddin Sawali, MBBS MS, Heng Gee Lee, MBChB MRCP, Ibtisam Ismail, BSc, Ida Sadja'ah Sachlin, MBBS MMed, Jeyasakthy Saniasiaya, MMed FEBORL, Jothi Shanmuganathan, MBBS MMed, Kuldip Kaur Prem Kaur, MBBS MPH, Lee Lee Low, MD MRCP, Linda Pei Fang Lim, MD MS, Mahiran Mustafa, MBBCh MMed, Masliza Zaid, MBBS MMed, Mohd Noor Ismail, MD MRCP, Mohd Zambri Ibrahim, MD MMed, Nor Zaila Zaidan, MD MMed, Norzi Gazali, MBBS MMed, Philip Rajan Devesahayam, MMed FRCS, Rosdi Ramli, MBBS MMed, Shahrul Aiman Soelar, B Ind Stats, Sharifah Baizura Syed Alwi, MD MRCPI, Shen-Han Lee, MB PhD MRCS, Siti Sabzah Hashim, MD MS, Siti Sabzah Mohd Hashim, MD MS, Siti Sabzah bt Mohd Hashim, MD, MS, Sobani Din, MD MS, Suhaila Abd Wahab, MBBS MMed, Suhaimi Yusof, MBBS MMed, Suhaimi Yusuf, MBBS MMed, Tengku Mohamed Izam Tengku Kamalden, MS FRCS, Tiang Koi Ng, MBBS MRCP, Ting Soo Chow, MD MRCP, Zhi Xiang Yeoh, MBBS MS MRCS, Zulkiflee Salahuddin, MD MS 2020-05-19
A pilot clinical trial of AntiCovir for the prevention of COVID-19 infection Coronavirus disease 19 infection interferon alpha-2b (COVID-19, inhaled), Altum Pharmaceuticals alone Interferon alpha ligand modulator Altum Pharmaceuticals Inc, BLife Therapeutics Inc US 2020-12-31 Phase Not Applicable Planned 0 2020-05-18
NO-COVID-19: Inhaled Nitric Oxide for Preventing Progression in COVID-19 Coronavirus disease 19 infection nitric oxide (inhaled, INOpulse), Bellerophon alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tufts Medical Center Bellerophon Therapeutics LLC US 2020-05-12 2021-07-31 NCT04388683, NO-COVID-19, STUDY00000554 Phase 2 Clinical Recruiting 0 14 Months 42 Marvin Konstam, MD, Nicholas Hill, MD 2020-05-19
A pilot, phase II, randomized, double-blind, placebo controlled trial of interferon alpha-2b for the treatment of COVID-19 infection Coronavirus disease 19 infection interferon alpha-2b (COVID-19, inhaled), Altum Pharmaceuticals alone Interferon alpha ligand modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Altum Pharmaceuticals Inc Australia 2020-07-31 ALT-003-COV-01 Phase 3 Clinical Planned 1 306 2020-05-18
COVID-19 Treatment of Severe Acute Respiratory Syndrome With Veru-111 Coronavirus disease 19 infection, Respiratory distress syndrome VERU-111 alone Tubulin alpha inhibitor, Tubulin beta inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Veru Inc US 2020-05-25 2020-08-30 NCT04388826, V0211901 Phase 2 Clinical Not yet recruiting 0 3 Months 40 Domingo Rodriguez, Gary Barnette, Karen Lewandowski 2020-05-20
COVIDOR: Epidemiological Study of the Covid-19 Presto Test Coronavirus disease 19 infection Covid-19 presto test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Orléans Métropole Service de Médecine Préventive Universite Francois Rabelais de Tours France 2020-06-18 2022-01-18 2020-A01414-35, COVIDOR, NCT04387968 Phase Not Applicable Not yet recruiting 1 19 Months 700 Loic CLECH, MD, Mélanie MONSION, IDEST, Pr Raphaël O SERREAU, MD-PhD, Raphael Serreau, Raphaël SERREAU, MD, PhD 2020-05-18
SEROSARSCOV: Study of the SARS-COV-2 (COVID-19) Serological Profile of an Army Training Hospital Staff Coronavirus disease 19 infection ELISA alone, EVOLIS analyzer (Biorad) alone, blood sampling alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Direction Centrale du Service de Sante des Armees France 2020-05-13 2020-06-24 2020-COVID19-10, NCT04387838, SEROSARSCOV Phase Not Applicable Not yet recruiting 2 1 Month 900 David TRAN-VAN, MD, Elodie VALERO, PharmD, Frédéric JANVIER, MD 2020-05-18
Post COVID-19 Cardiopulmonary and Immunological Changes (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Mansoura University Egypt 2020-05-11 2021-10-10 20.05.67, NCT04388436 Phase Not Applicable No longer recruiting 1 17 Months 100 Tamer A Elhadidy, MD 2020-05-20
PRAISE@COVID: Screening Patients for a Strategic Shift to Pulmonary Telerehabilitation Because of COVID-19 Coronavirus disease 19 infection, Respiratory disease pulmonary telerehabilitation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidade de Lisboa Fundacao para a Ciencia e a Tecnologia, Hospital de Santa Maria, Nippon Gases Portugal, Unipessoal, Lda. Portugal 2020-03-20 2020-03-27 046I/17, NCT04388579, PRAISE@COVID Phase Not Applicable Completed 3 100 Catarina D Santos, MSc, Cristina Bárbara, PhD 2020-05-18
Protecting Health Care Workers During the COVID-19 Outbreak Coronavirus disease 19 infection ayurvedic kadha intake alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Aarogyam UK Samta Ayurveda Prakoshtha India 2020-03-01 2020-04-02 AU/SA/01, NCT04387643 Phase Not Applicable Completed 1 1 Month 52 Jaydeep Joshi, Neha Sharma, Parashar Sharma, Sahil Singhal 2020-05-18
Evaluation of colchicine in treatment of coronavirus Coronavirus disease 19 infection chloroquine plus colchicine Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ardabil University of Medical Sciences Iran 2020-05-04 IR.ARUMS.REC.1399.050, IRCT20200418047126N1 Phase 3 Clinical Recruiting 1 100 Farhad Pourfarzi, Farhad Salehzadeh, Haleh Valizadeh Haghi, Shahram Habibzadeh 2020-05-18
CLOT: COVID-19, Blood Coagulation and Thrombosis Coronavirus disease 19 infection, Deep vein thrombosis, Lung embolism, Respiratory failure, Viral pneumonia CT scan alone, echo-Doppler ultrasound alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ramsay Générale de Santé Hôpital Privé Jacques Cartier, service réanimation Dr Bougouin France 2020-05-01 2020-09-01 2020-A00, CLOT, NCT04388657 Phase Not Applicable Recruiting 3 4 Months 100 DRE Ramsay santé, Guillaume Peri, Dr, JEAN F OUDET, Julien Nahum, Dr, MH barba, Wulfran Bougouin 2020-05-18
Favipiravir versus Hydroxychloroquine in COVID-19 Coronavirus disease 19 infection Plaquenil alone, antiviral treatment alone, favipiravir alone, supportive care alone RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Royal College of Surgeons in Ireland - Medical University of Bahrain Bahrain Defence Force Royal Medical Services, Military Hospital, Ebrahim Khalil Kanoo Community Medical Center Bahrain 2020-05-14 2020-08-14 40 / 07-MAY-2020, NCT04387760 Phase 2/Phase 3 Clinical Not yet recruiting 1 3 Months 150 Abdulkarim Abdulrahman, Dr., Manaf Al Qahtani, Dr., Mohamed Wael, Dr., Omar Yaghi, Dr., Pearl Wasif, MSc., Salman Yousif Alali, Dr., Sameer Otoom, Prof., Sawsan Saeed, MDPH, Stephen Atkin, Prof. 2020-05-18
Serologic Surveillance for SARS-CoV-2 (COVID-19) in a Prospective, Cohort of Health Care Workers Coronavirus disease 19 infection quantitative indirect chemiluminescence immunoassay alone, serological testing alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Italiano de Buenos Aires Roche Pharma (Schweiz) AG Argentina 2020-05-15 2020-08-31 5566, NCT04387890 Phase Not Applicable Not yet recruiting 1 3 Months 50 Cristina Elizondo, MD, Diego Sanchez Thomas, MD, Ines Staneloni, MD, Leticia Peroni, MD, Vanina Stanek, MD 2020-05-20
Stem cell treatment for COVID-19 Coronavirus disease 19 infection, Viral pneumonia human umbilical cord Wharton’s jelly mesenchymal stem cells alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) DEY Company Iran 2020-05-12 IR.SBMU.RETECH.REC.1399.031, IRCT20200421047150N1 Phase 2/Phase 3 Clinical Recruiting 1 90 Ali Asghar Rezaei, Mehran Lak, Mohamad Fathi 2020-05-19
ACROVID: Analysis of Chilblains profile During COVID-19 Epidemic Coronavirus disease 19 infection, Frostbite anal swabbing alone, biological sampling alone, blood test alone, skin biopsy alone Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire De Poitiers Etablissement D’Hospitalisation 2020-05-31 2021-06-30 ACROVID, ACROVID, NCT04387955 Phase Not Applicable Not yet recruiting 0 13 Months 30 Damien BOUTIN 2020-05-18
A clinical trial of allogeneic iNKT cell-based immunotherapy for the treatment of COVID-19 infection Coronavirus disease 19 infection agenT-797 alone AgenTus Therapeutics Inc Phase Not Applicable Planned 0 2020-05-20
Interferon Lambda Therapy for COVID-19 Coronavirus disease 19 infection peginterferon lambda-1a, Eiger BioPharmaceuticals alone Interferon receptor modulator, Interleukin-29 ligand Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mount Sinai Medical Center Eiger BioPharmaceuticals Inc US 2020-04-30 2021-05-31 GCO 20-0820, NCT04388709 Phase 2 Clinical Recruiting 0 13 Months 66 Lynn Bui, Thomas Marron, MD 2020-05-19
QUALICOVID: Care in Patients Hospitalized for Anorexia Nervosa at the Time of the Coronavirus-19 Epidemic Anorexia nervosa, Coronavirus disease 19 infection intensive outpatient care alone, teleconsultation interview alone, telephone hotline alone, telephone interview alone Healthy volunteers accepted Centre Psychothérapique de Nancy France 2020-05-14 2020-06-08 NCT04387708, QUALICOVID, RIPH 2020-01 Phase Not Applicable Not yet recruiting 1 18 Marilou Lamourette, MD, Tatiana Dabrowski 2020-05-18
DACOVID: Dornase Alfa Administered to Patients With COVID-19 Coronavirus disease 19 infection albuterol plus dornase alfa Deoxyribonuclease I stimulator, Deoxyribonuclease stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Feinstein Institute for Medical Research Cold Spring Harbor Laboratory US 2020-03-31 2020-07-31 216, DACOVID, NCT04387786 Phase Not Applicable No longer recruiting 0 4 Months 5 Betsy J Barnes 2020-05-19
EPCOvid-1: Safety and Efficacy of Convalescent Plasma Transfusion for Patients With COVID-19 Coronavirus disease 19 infection convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto Nacional de Ciencias Medicas y Nutricion Hospital General Dr. Manuel Gea González, Hospital Regional de Alta Especialidad del Bajio, Hospital San Jose Tec de Monterrey, Instituto Nacional De Cancerologia, Instituto Nacional de Cardiologia Ignacio Chavez, Instituto Nacional de Enfermedades Respiratorias Mexico 2020-06-01 2020-12-31 3380, EPCOvid-1, NCT04388410 Phase 2/Phase 3 Clinical Not yet recruiting 1 7 Months 250 Juan G. Sierra Madero 2020-05-18
Influence of COVID-19 Infection on sensory organs in othorynolaryngology Coronavirus disease 19 infection ENT medical examination alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Klinikum der Albert-Ludwigs Universitaet Freiburg Germany 2020-05-20 270/20, DRKS00021664, U1111-1250-9799 Phase 0 Clinical Not yet recruiting 1 100 Kathrin Potkowski 2020-05-18
Investigating the efficacy and safety of Interferon Beta1a nasal spray in controlling the symptoms of patients with COVID-19 Coronavirus disease 19 infection interferon beta 1a nasal spray alone, routine treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bagheiat-allah University of Medical Sciences, CinnaGen Co Iran 2020-05-14 IR.BMSU.REC.1399.122, IRCT20080901001165N53 Phase 3 Clinical Recruiting 1 100 Mostafa Ghanei, Parisa Kianpour, Seyed Hasan Saadat, Yunes Panahi 2020-05-19
NCCAPS: NCI COVID-19 in Cancer Patients Coronavirus disease 19 infection, Hematological neoplasm, Solid tumor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Cancer Institute US 2020-05-17 2023-05-31 NCCAPS, NCI-2020-02986, NCICOVID, NCT04387656 Phase Not Applicable Not yet recruiting 0 36 Months 2000 Larissa A Korde 2020-05-15
ASPIRE: Assessing the Safety of Pregnancy In the Coronavirus (COVID-19) Pandemic Coronavirus disease 19 infection Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of California San Francisco US 2020-04-21 2022-09-30 20-30559, ASPIRE, NCT04388605 Phase Not Applicable Recruiting 0 29 Months 11000 Eleni Jaswa, MD, MSc, Heather Huddleston, Heather Huddleston, MD 2020-05-16
Investigating Anosmia and Ageusia in COVID-19 Adult Patients in Saudi Arabia Ageusia, Coronavirus disease 19 infection, Dysomia NHANES smell and taste tests alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Princess Nourah Bint Abdulrahman University Saudi Arabia 2020-06-01 2020-12-31 20-0189, NCT04388618 Phase Not Applicable Not yet recruiting 1 7 Months 250 AHMAD AALIBRAHIM, M.D, Abdulaziz s Algarni, MD, KHALED SOLIMAN, M.D, Khaled R Suliman, M.D, MARZOOQA ALENIZI, M.D, OSAMA KENTAB, M.D, Osama Y Kentab, M.D, Osama Y Kentab, MD 2020-05-20
DORM: A randomized, open-label prophylaxis trial among migrant workers at high-risk of Covid-19 Coronavirus disease 19 infection Variable regimens including hydroxychloroquine , ivermectin , povidone-iodine , vitamin C , zinc Chloride channel modulator National University Hospital (Singapore) Pte Ltd Singapore 2020/00561, DORM Phase 3 Clinical Status not specified 1 Dr Raymond Seet Chee Seong 2020-05-18
Immunological efficacy of Jinhua Qinggan Granule for COVID-19 Coronavirus disease 19 infection Jinhua qinggan granules alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Tokyo Takanawa Hospital Japan 2020-05-15 UMIN000040407 Phase Not Applicable No longer recruiting 2 15 Tomoka Ebisui, Tsutomu Nakamura 2020-05-19
Detection of Anti-COVID-19 Antibody Levels in an Hospital Population Coronavirus disease 19 infection RT-PCR alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Istituto Clinico Humanitas Italy 2020-05-04 2021-05-30 1374 IGG COVID-19 HUMANITAS, NCT04387929 Phase Not Applicable Recruiting 1 12 Months 6000 Patrizia Meroni, MD 2020-05-18
Survey of Satisfaction on Traditional Chinese Medicine Jing-Guan-Fang (JGF) for COVID-19 Prevention Coronavirus disease 19 infection Jing-Guan-Fang alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Taipei City Hospital National Yang Ming University Taiwan 2020-02-20 2020-05-30 NCT04388644, TCHIRB-10904015-E Phase Not Applicable Recruiting 3 3 Months 300 Chung Hua Hsu, PhD, Chung-HUa Hsu, PhD, Chung-Hua Hsu, MD, PhD, WEN-YING SUNG, MD, Master 2020-05-18
2019nCoV_ICU: Epidemiological and Clinical Characteristics of Critically Ill Patients With COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Policlinico Hospital Italy 2020-02-22 2020-08-31 2019nCoV_ICU, NCT04388670, POLICLINICOH Phase Not Applicable Recruiting 2 6 Months 1500 Giacomo Grasselli, Associate Professor, Giacomo Grasselli, MD 2020-05-18
A feasibility study of remote rehabilitation using a wearable biological monitoring device in the patients with COVID-19 Coronavirus disease 19 infection remote rehabilitation alone, wearable biological monitoring device alone Tokyo Medical and Dental University Japan 2020-05-15 UMIN000040401 Phase Not Applicable Recruiting 1 100 Tomoyuki Umemoto 2020-05-18
PRESCO: Predictors of Severe COVID-19 Outcomes Coronavirus disease 19 infection, Respiratory distress syndrome Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Verily Life Sciences LLC US 2020-05-31 2021-03-31 102293, NCT04388813, PRESCO Phase Not Applicable Not yet recruiting 0 10 Months 1500 2020-05-18
COVID-19 Convalescent Plasma for Mechanically Ventilated Population Coronavirus disease 19 infection, Viral pneumonia convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Pennsylvania US 2020-04-30 2020-09-30 842996 (PENNCCP-01), NCT04388527 Phase 1 Clinical Recruiting 0 5 Months 50 Julie Starr, Katharine J. Bar, MD 2020-05-18
Detection Rate of SARS-CoV-2 in Male Genitourinary System and Its Impact on Male Reproductive Health(COVID-19) Coronavirus disease 19 infection, Viral pneumonia Healthy volunteers accepted, Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Tongji Hospital China 2020-05-10 2021-05-01 2020-S073, NCT04388631 Phase Not Applicable Recruiting 1 11 Months 200 Jihong Liu, Jihong Liu, M.D, Tao Wang, M.D 2020-05-19
NPC-19: Negative-PCR for Covid- 19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Catholic University of the Sacred Heart Italy 2020-05-13 2020-07-10 20200505, NCT04387799, NPC-19 Phase Not Applicable Recruiting 1 1 Month 260 Anna Caprodossi, Antonio Gasbarrini, MD, Geltrude Mingrone, MD, Giovanni Addolorato, MD, Maria F Russo, MD 2020-05-18
PROTECT: Preventative treatment for patients at risk of COVID-19 infection Coronavirus disease 19 infection hydroxychloroquine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cambridge University Hospitals NHS Foundation Trust, University of Cambridge April Trust UK 2020-04-03 2025-05-03 2020-002016-48, CCTU0307, IRAS282317, ISRCTN88057279, PROTECT Phase 2/Phase 3 Clinical Recruiting 1 61 Months 500 Dr Hiemstra, Kerry Brusby 2020-05-18
A phase I trial to evaluate mRNA vaccine (LPP delivery platform, COVID-19), Shanghai Yinuosi Biotechnology/Tongji University/Biocad/Stemrina Therapeutics for the prevention of SARS-CoV-2 infection Coronavirus disease 19 infection mRNA vaccine (LPP delivery platform, COVID-19), Shanghai Yinuosi Biotechnology/Tongji University/Biocad/Stemrina Therapeutics alone Biocad Ltd Russian Federation 2020-10-31 Phase 1 Clinical Planned 1 2020-05-15
Radiographic findings and their temporal changes in COVID-19 positive patient: A Prospective study Coronavirus disease 19 infection reverse transcriptase polymerase chain reaction test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Max Super Speciality Hospital India 2020-05-06 CTRI/2020/05/025041 Phase Not Applicable Not yet recruiting 1 200 Dr Bharat Kumar, Dr Saroj Kumar sabath, Rajesh Saxena 2020-05-18
Use of High Flow Nasal Cannula Oxygen and COVID-19 Acute Hypoxemic Respiratory Failure Coronavirus disease 19 infection, Hypoxia, Respiratory failure, Viral pneumonia nasal high flow cannula oxygen therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hôpital Louis Mourier France 2020-03-01 2020-05-04 HLM_JDR9, NCT04385823 Phase Not Applicable Completed 1 2 Months 62 Jean-Damien Ricard, MD, PhD, Prof Jean-Damien RICARD 2020-05-18
Photobiomodulation Therapy Combined With Static Magnetic Field in Patients With COVID-19 Coronavirus disease 19 infection, Respiratory failure MR5 Activ Pro LaserShower (Multi Radiance Medical) alone, photobiomodulation therapy alone, standard physical therapy alone, static magnetic field therapy alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidade Nove de Julho Hospital Tacchini/RS Brazil 2020-05-11 2020-07-31 3.985.226, NCT04386694 Phase Not Applicable Not yet recruiting 1 2 Months 30 Ernesto Cesar Leal Junior, PhD, Ernesto Cesar Pinto Leal Junior, Thiago De Marchi, PhD 2020-05-20
Oral 25-hydroxyvitamin D3 and COVID-19 Coronavirus disease 19 infection 25-hydroxyvitamin D3 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Tehran University of Medical Sciences Boston University Iran 2020-04-14 2021-03-15 IR.TUMS.VCR.REC.1399.061, IRCT2020-0401046909N2, IRCT20200401046909N1, NCT04386850 Phase 3 Clinical Recruiting 5 11 Months 1500 Arash shirvani, Mohamadali Sahraian, MD, Zhila Maghbooli, PhD, zhila Maghbooli, PhD, zhila maghbooli, PhD 2020-05-15
Study of the Safety of Therapeutic Treatment With an Immunomodulary Agent (N-803 in Adults With COVID-19) Coronavirus disease 19 infection N-803 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) ImmunityBio Inc 2020-05-11 2020-07-11 NCT04385849, QUILT-COVID-19 Phase 1b Clinical Not yet recruiting 0 2 Months 30 Jeff Safrit 2020-05-18
Vitamin D and COVID-19 Management Coronavirus disease 19 infection, Vitamin D deficiency ergocalciferol alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Alberta Canada 2020-05-31 2020-12-31 00100606, NCT04385940 Phase 3 Clinical Not yet recruiting 1 7 Months 64 Aldo Montano-Loza 2020-05-14
Taiwan 'Aerosol Box' Versus UMMC 'Intubation Box' Coronavirus disease 19 infection Aerosol Box alone, Intubation Box alone Healthy volunteers accepted University of Malaya Malaysia 2020-05-15 2020-12-30 2020410-8498, NCT04385576 Phase Not Applicable Recruiting 1 7 Months 30 Dr SHAIRIL RAHAYU BINTI RUSLAN, INA I SHARIFFUDDIN, MAnaes, MOHD F ZAINAL ABIDIN, MAnaes, SHAIRIL R RUSLAN, MAnaes(UM) 2020-05-14
Neonatal Complications of Coronavirus Disease (COVID-19) Coronavirus disease 19 infection Newborn Infants (up to 5 months) University of Oxford Imperial College London, Public Health England, St Georges University of London, University Hospital of Wales, University of Glasgow, University of Leicester, University of Nottingham UK 2020-04-01 2021-09-30 14905, NCT04386109 Phase Not Applicable Recruiting 1 18 Months 500 Dr C Gale, MBBS,MSc,PhD, Professor J Kurinczuk, MBChB,MSc,MD 2020-05-15
SALICOV: Detection of COVID-19 in Saliva Collection Coronavirus disease 19 infection saliva sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire D Amiens France 2020-05-11 2020-08-31 NCT04386551, PI2020_843_0045, SALICOV Phase Not Applicable Recruiting 1 3 Months 225 Catherine François, MD, Etienne Brochot, MD, Jean-Luc Schmit, Pr, Jean-Philippe Lanoix, MD, Sandrine Castelain, Pr, Yves Edouard Herpe, Ing 2020-05-15
A Phase III, Double-blind, Randomized, Placebo-controlled, Multicenter Clinical Trial to Assess the Efficacy and Safety of VPM-1002 in Reducing Healthcare Professionals' Absenteeism in the SARS-CoV-2 Pandemic by Modulating the Immune System Coronavirus disease 19 infection, Respiratory disease VPM-1002 alone Listeriolysin stimulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Vakzine Projekt Management GmbH FGK Clinical Research GmbH Germany 2020-05-18 2021-06-30 NCT04387409, VPM1002-DE-3.06COV Phase 3 Clinical Not yet recruiting 1 13 Months 1200 Leander Grode, Dr rer nat 2020-05-14
Ayurvedic Interventions in prevention of COVID-19 infection-A survey study Coronavirus disease 19 infection Ashwagandha plus Sanshamani Vati Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Central Council for Research in Ayurvedic Sciences India 2020-05-16 CTRI/2020/05/025069 Phase 3 Clinical Not yet recruiting 1 1324 Dr BCS Rao, Dr Babita Yadav 2020-05-14
A Study to Evaluate the Safety and Efficacy of MSTT1041A (Astegolimab) or UTTR-1147A in Patients With Severe COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia RG-6149 alone, RG-7880 alone IL-22 agonist, Interleukin 1 like receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Genentech Inc US 2020-05-20 2020-10-27 GA42469, NCT04386616 Phase 2 Clinical Not yet recruiting 0 5 Months 300 Clinical Trials 2020-05-15
Can a medicine help in curing viral infection Coronavirus disease 19 infection ivermectin alone Chloride channel modulator Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Christian Medical College, Vellore, India, Science and Engineering Research Board India CTRI/2020/05/025068 Phase 2b Clinical Not yet recruiting 1 50 Biju George 2020-05-18
Covid-19 and Prevention of Malnutrition After Confinement by Dentists Coronavirus disease 19 infection, Malnutrition medical consultation alone, nutritional supplement intake alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire De Nice France 2020-05-11 2021-05-11 20ODONTOCOVID-02, NCT04386460 Phase Not Applicable Recruiting 1 12 Months 100 Isabelle precheur, Isabelle precheur, PUPH, isabelle precheur, valerie Pouyssegur, PH 2020-05-18
CYCOV-II: Cytokine Adsorption in Patients With Severe COVID-19 Pneumonia Requiring Extracorporeal Membrane Oxygenation Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia Cytosorb adsorber alone, cytokine adsorption alone, extracorporeal membrane oxygenation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Klinikum der Albert-Ludwigs Universitaet Freiburg Kliniken Ludwigsburg-Bietigheim gGmbH, Klinikum Ibbenbüren, Ludwig-Maximilians University of Munich, Martin-Luther-Universitaet, SLK Klinikum Heilbronn GmbH, Saarland University Hospital, Universitat Ulm Germany 2020-06-01 2021-10-31 CYCOV-II, CYCOV-II, NCT04385771 Phase Not Applicable Not yet recruiting 1 17 Months 80 Alexander Supady, Dr., MPH 2020-05-15
A clinical trial to investigate the anti-inflammatory properties of cannabidiol in COVID-19 patients with cardiac injury Coronavirus disease 19 infection, Heart injury cannabidiol alone Cardiol Therapeutics Inc Phase Not Applicable Status not specified 0 2020-05-14
Phase II Clinical Trial Evaluating FUJIFILM Toyama Chemical’s Favipiravir as a Preventative Measure Against COVID-19 in Canadian Long-Term Care Facilities Coronavirus disease 19 infection favipiravir alone RNA polymerase inhibitor Appili Therapeutics Inc Canada Phase 2 Clinical Planned 1 2020-05-15
A clinical trial of Ad5-nCoV for the treatment of COVID-19 infection Coronavirus disease 19 infection Ad5-nCoV alone COVID19 Spike glycoprotein modulator CanSino Biologics Inc, Canadian Center for Vaccinology, Canadian Immunization Research Network, National Research Council of Canada Canada Phase Not Applicable Not yet recruiting 1 2020-05-20
CONNECTDEM: Cognitive Outcomes During COVID-19 confinement in Elderly and Their Caregivers Using Technologies for Dementia Acute stress disorder, Coronavirus disease 19 infection, Dementia, Depression, Mild cognitive impairment telephone interview alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundacion Publica Andaluza para la Investigacion de Malaga en Biomedicina y Salud Consorci Sanitari de Terrassa Spain 2020-05-04 2020-06-30 CONNECT DEM, CONNECTDEM, NCT04385797 Phase Not Applicable Not yet recruiting 2 1 Month 414 Fermín Mayoral-Cleries, Fermín Mayoral-Cleries, MD, PhD, Jessica M Goodman-Casanova, RNCS, Maite Garolera, PhD, María Quintana, PhD 2020-05-15
Compassionate Use of Hyperbaric Oxygen Therapy Coronavirus disease 19 infection hyperbaric oxygen therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) SerenaGroup The Wound Treatment Center Poland, US 2020-05-11 2022-05-11 HBOT-COVID-19, NCT04386265 Phase Not Applicable Recruiting 0 24 Months 100 Thomas E Serena, MD 2020-05-20
Kidney Injury Severity and COVID-19 Coronavirus disease 19 infection, Renal injury, Respiratory distress syndrome, Viral pneumonia CT scan alone, urine test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) IM Sechenov Moscow Medical Academy Russian Federation 2020-05-15 2020-11-15 NCT04386564, SECHENOV-COVID19_AKI Phase Not Applicable Not yet recruiting 1 6 Months 120 Dmitry Enikeev, M.D., Ph.D., Dmitry Enikeev, MD, Mark Taratkin, M.D. 2020-05-14
A randomized, double-blinded, parallel-controlled clinical trial for azvudine in the treatment of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Standard of Care alone, azvudine alone Nucleoside reverse transcriptase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Beijing Ditan Hospital Capital Medical Universty China 2020-05-12 ChiCTR2000032769 Phase 2 Clinical Recruiting 6 342 Wan Yuanhao, Zhang Fujie 2020-05-14
Trial of Alpha-1 Antitrypsin Inhalation in Treating Patient With Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) Coronavirus disease 19 infection alpha-1 antitrypsin (iv, alpha-1 antitrypsin deficiency/type 1 diabetes/GvHD/ lung transplant rejection), Kamada/Shire alone Alpha 1 antitrypsin stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ministry of Health Saudi Arabia Saudi Arabia 2020-06-01 2020-09-01 4-0520- 076-K-02-H, NCT04385836 Phase 0 Clinical Recruiting 1 3 Months 150 mohammed m othman, mtair 2020-05-15
Evaluation of the use of hydroxychlorochine in Chinese flu Coronavirus disease 19 infection proper COVID19 treatment alone, azithromycin plus hydroxychloroquine Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital da Criança Santo Antônio Brazil 2020-05-01 Número do CAAE: 30585020.2.0000.0008, Número do Parecer do CEP: 3.982.682, RBR-3k4wxb, U1111-1250-7492 Phase 2 Clinical Not yet recruiting 1 45 Marcos Aurelio Barboza de Oliveira 2020-05-14
The Philippine CORONA: Neurological Manifestations of COVID-19 (CORONA) Coronavirus disease 19 infection, Neurological disease Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of the Philippines Asian Hospital and Medical Center, Baguio General Hospital and Medical Center, Cagayan Valley Medical Center, Capitol Medical Center, Cardinal Santos Medical Center, Chong Hua Hospital, De La Salle University Medical Center, Dr. Pablo O. Torre Memorial Hospital, East Avenue Medical Center, Jose B. Lingad Memorial Regional Hospital, Jose R. Reyes Memorial Medical Center, Lung Center of the Philippines, Makati Medical Center, Manila Doctors Hospital, Manila Medical Center, New Era General Hospital, Ospital ng Makati, Philippine Heart Center, Quirino Memorial Medical Center, Research Institute for Tropical Medicine, San Juan De Dios Educational Foundation Inc. - Hospital, San Lazaro Hospital, Southern Isabela Medical Center, Southern Philippines Medical Center, St Lukes Medical Center, Bonifacio Global City, St. Luke's Medical Center, The Medical City, Philippines, University of Santo Tomas Hospital, University of the East Ramon Magsaysay Memorial Medical Center, Inc, Veterans Memorial Medical Center Philippines 2020-05-31 2021-03-31 NCT04386083, RGAO-2020-0348, The Philippine CORONA Phase Not Applicable Not yet recruiting 1 10 Months 1342 Adrian I Espiritu, MD, Roland Dominic G Jamora, MD 2020-05-18
A Clinical Study on Favipiravir Compared to Standard Supportive Care in Patients With Mild to Moderate COVID-19 Coronavirus disease 19 infection Standard Supportive Care alone, favipiravir alone RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Glenmark Pharmaceuticals Ltd India 2020-05-20 CTRI/2020/05/025114, GPL/CT/2020/002/III Phase 3 Clinical Not yet recruiting 5 150 Amol Pendse, Dr Abdul Ansari, Dr Atul Jindal, Dr Bharat Purandare, Dr Chandrakant Pawar, Dr Keyur Madan Brahme, Dr Meenakshi Bhattacharya, Dr Pawan Singh, Dr Rajesh Gosavi, Dr Tanu Singhal, Dr Urman Dhruv 2020-05-19
Study of effect of Yashtimadhu tablet for the prevention of COVID -19 on healthy individuals Coronavirus disease 19 infection Yashtimadhu alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ministry of Ayush India 2020-05-18 CTRI/2020/05/025093 Phase 2/Phase 3 Clinical Not yet recruiting 1 1200 Dr G Babu, Dr Sujata Pundalikrao Dhoke, Dr Sujata pundlikrao Dhoke 2020-05-15
The effect of zinc on the treatment and clinical course of patients with SARS-cov2 (COVID-19) Coronavirus disease 19 infection hydroxychloroquine sulfate plus zinc Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Isfahan University of medical Sciences Iran 2020-04-20 IR.MUI.MED.REC.1399.074, IRCT20180425039414N2 Phase 2/Phase 3 Clinical Recruiting 1 80 Atousa Hakamifard, Ziba Farajzadegan 2020-05-15
To study the Effectiveness of herbal formulation - Aayudh Advance as a supplementary treatment for the Corona Virus 2019 (Covid-19) infected patients Coronavirus disease 19 infection Herbal formulation - Aayudh Advanced alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shukla Ashar Impex Pvt. Ltd., Rajkot India 2020-05-16 ARL/CSP/2020/002-01, CTRI/2020/05/025161 Phase 2 Clinical Recruiting 1 120 Dr Bhavdeep Ganatra, Dr Jayesh Dutt, Dr Manish Rachchh 2020-05-18
Pa-COVID-19: Analysis of the Pathophysiology and Pathology of Corona Virus Disease 2019 Coronavirus disease 19 infection Charité Campus Virchow-Klinikum Charite Universitaetsmedizin Berlin Germany 2020-03-01 DRKS00021688, EA2/066/20, Pa-COVID-19 Phase Not Applicable Recruiting 1 1500 Florian Kurth, Leif-Erik Sander 2020-05-15
COMBAT-COVID-19: Efficacy and safety of 72-h infusion of Prostacyclin (1 ng/kg/min) in patients with COVID-19 induced respiratory failure - a multicenter, randomized, placebo-controlled, blinded, investigator-initiated trial Coronavirus disease 19 infection, Respiratory failure iloprost (inhaled nebulizer formulation, pulmonary hypertension), Bayer Schering/Actelion alone PGI2 agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Copenhagen University Hospital, Hvidovre Denmark 2020-05-06 2020-001296-33, COMBAT-COVID-19, COMBAT-COVID-19 Phase 2 Clinical Recruiting 1 80 Kristine Pedersen 2020-05-18
POVA-TIE: Measurement of Airway Opening Pressure (AOP) in Patients With Acute Respiratory Distress Syndrome and With or Without Covid 19 Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia PEEP derived electrical impedance tomography alone, global ventilator pressure volume measurement alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Bordeaux France 2020-05-20 2021-05-20 CHUBX 2020/15, NCT04386720, POVA-TIE Phase Not Applicable Not yet recruiting 1 12 Months 20 Eline BONNARDEL, Dr, Hadrien ROZE, Dr 2020-05-19
COVID-19 Pandemic and Academic Performance of Veterinary Students Coronavirus disease 19 infection online survey alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) South Valley University Egypt 2020-04-13 2020-05-15 1-2020, NCT04387214 Phase Not Applicable Recruiting 1 1 Month 400 Mohamed Mahdy 2020-05-16
Artificial ventilation setting in patients infected with COVID19 Coronavirus disease 19 infection, Respiratory distress syndrome Artificial ventilation alone, infusion pumps alone, mechanical ventilator alone, ultiparametric monitor alone, norepinephrine plus vasopressin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Universitario Pedro Ernesto, Universidade Federal do Rio de Janeiro Brazil 2020-04-29 3,997,807, 31050420.8.1001.5259, A32070754871, RBR-2z3f7k Phase Not Applicable Recruiting 1 30 Luciana Moisés Camilo, Monica Rodrigues Cruz, Tiago Batista da Costa Xavier 2020-05-19
Effect of Ayurveda intervention AYUSH-64 add-on therapy for patients with COVID-19 infection (Stage I) Coronavirus disease 19 infection AYUSH-64 alone, standard treament alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Central Council for Research in Ayurvedic Sciences India 2020-05-18 CTRI/2020/05/025156 Phase 3 Clinical Not yet recruiting 1 60 Dr R Govind Reddy, Dr Rajesh Vithal Gosavi 2020-05-19
HOP-COVID: COVID-19 Infection in Healthcare Workers Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-05-31 2020-10-31 APHP200483, HOP-COVID, NCT04386759 Phase Not Applicable Not yet recruiting 1 5 Months 6000 Sylvie BASTUJI-GARIN, MD, PhD 2020-05-15
A population-based study was to evaluate the whether androgen-deprivation therapies (ADTs) could protect patients affected by prostate cancer from SARS-CoV-2 infections Coronavirus disease 19 infection, Prostate tumor androgen-deprivation therapies alone Universita Degli Studi Di Padova Italy Phase Not Applicable Status not specified 1 Andrea Alimonti 2020-05-14
Demographics and Outcomes of COVID 19 in Pregnancy at a Community Based Hospital Coronavirus disease 19 infection, Pregnancy disorder COVID positive testing alone Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Atlantic Health System US 2020-05-31 2020-12-31 1595116-1, NCT04385914 Phase Not Applicable Not yet recruiting 0 7 Months 200 Farah Benarba, Samantha Collazo, MD 2020-05-18
The Impact of COVID-19 on the Health Care Utilization of Inflammatory Bowel Disease Coronavirus disease 19 infection, Inflammatory bowel disease Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Keimyung University Dongsan Medical Center Yeungnam University College of Medicine South Korea 2020-04-24 2021-03-30 2020-04-070, NCT04387279 Phase Not Applicable Recruiting 3 11 Months 800 Kyeong Ok Kim, Ph.D., Yoo Jin Lee, Yoojin Lee, M.D. 2020-05-17
Placebo-controlled clinical trial to evaluate the efficacy and safety of hydroxychloroquine and azithromycin in relation to placebo in the negative viral load of participants with SARS-CoV2 flu syndrome and who do not have an indication for hospitalization Coronavirus disease 19 infection, Viral pneumonia azithromycin plus hydroxychloroquine Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hospital Santa Paula Brazil 2020-04-11 3,964,568, 30413020.8.0000.0008, A 33166752803, RBR-95yjmq Phase 3 Clinical Recruiting 1 108 Ana Tarina Alvarez Lopes 2020-05-17
Phase Ib/II Trial of Dendritic Cell Vaccine to Prevent COVID-19 in Frontline Healthcare Workers and First Responders Coronavirus disease 19 infection AV-COVID-19 alone, AV-COVID-19 plus GM-CSF Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Aivita Biomedical Inc 2020-09-30 2021-04-30 CL-COV-P01-US, NCT04386252 Phase 1/Phase 2 Clinical Not yet recruiting 0 7 Months 180 Candace Hsieh, PhD, Robert O Dillman, MD 2020-05-17
OsCOVID19: Phase II RCT to Assess Efficacy of Intravenous Administration of Oxytocin in Patients Affected by COVID-19 Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia deep vein thrombosis prophylaxis treatment alone, non-invasive ventilation alone, oxygen therapy alone, steroid therapy alone, Variable regimens including azithromycin , darunavir + cobicistat , hydroxychloroquine , lopinavir + ritonavir , oxytocin , remdesivir Coronavirus non structural protein 8 modulator, HIV protease inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Azienda Ospedaliero-Universitaria di Parma Universita' Degli Studi Di Parma France, Italy 2020-06-03 2020-12-31 NCT04386447, OSCOVID19, OsCOVID19 Phase 2 Clinical Not yet recruiting 4 6 Months 145 Angela Sirigu, PhD, Antonina Carai, MD, Antonio Nouvenne, MD,PhD, Antonio Nouvenne, MD,Phd, Carlo Ferrari, MD,Phd, Caterina Caminiti, PhD, Gianluca Deiana, MD, PhD, Giuseppe Maglietta, PhD, Licia Abbruzzese, MD, Lorenzo Finardi, MD,Phd, Peppino Paffi, MD, Pier Francesco Ferrari, PhD, Riccardo Volpi, MD,PhD, Tiziana Meschi, Tiziana Meschi, MD, PhD, Tiziana Meschi, MD,PhD 2020-05-20
Evaluating the Efficacy of Artesunate in Adults With Mild Symptoms of COVID-19 Coronavirus disease 19 infection artemisinin alone, artesunate alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Princess Nourah Bint Abdulrahman University Saudi Arabia 2020-06-30 2020-12-31 IN PROCESS, NCT04387240 Phase 2 Clinical Not yet recruiting 1 6 Months 22 Abdulaziz S Algarni, MD, Osama Kentab, MD, Osama Y Kentab, MD 2020-05-18
APRV-COVID19: Evaluation of Airway Pressure Release Ventilation in COVID-19 ARDS Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia Airway pressure release ventilation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Hospital, Nancy, France France 2020-05-15 2020-06-30 2020PI076, APRV-COVID19, NCT04386369 Phase Not Applicable Not yet recruiting 1 1 Month 40 Matthieu Koszutski, MD 2020-05-17
Study on the Use of Sarilumab in Patients With COVID-19 Infection Coronavirus disease 19 infection Variable regimens including chloroquine , hydroxychloroquine , sarilumab IL-6 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) ASST Fatebenefratelli Sacco Italy 2020-05-31 2020-12-31 COVID-SARI-001, NCT04386239 Phase 0 Clinical Not yet recruiting 1 7 Months 40 Agostino Riva, MD, Massimo Galli, Professor, Stefano Rusconi 2020-05-17
COVIDIMM: Immune Changes in Severe COVID-19 Pulmonary Infections Coronavirus disease 19 infection, Hypoxia, Lung infection, Respiratory failure NAVIOS flow cytometer (Beckman Coulter) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Hospital, Nancy, France France 2020-03-30 2020-05-30 CHRU NANCY : 2020PI080_1, COVIDIMM, NCT04386395 Phase Not Applicable No longer recruiting 1 2 Months 15 MARIE REINE LOSSER, MD, PhD 2020-05-17
COVIDANCE: Losartan and spironolactone treatment for COVID-19 patients with acute respiratory failure in intensive care unit Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure losartan alone, spironolactone alone Aldosterone antagonist, Angiotensin II AT-1 receptor antagonist, Angiotensin II receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux De Marseille France 2020-04-29 2020-001766-11, 2020-24, COVIDANCE Phase 2 Clinical Recruiting 1 clinical project manager 2020-05-18
GYNE-COVID: Study of Late Fetal Loss in Poitou-Charentes Coronavirus disease 19 infection, Spontaneous abortion polymerase chain reaction alone Healthy volunteers accepted Centre Hospitalier Universitaire De Poitiers Etablissement D’Hospitalisation France 2020-05-04 2021-07-04 GYNE-COVID, GYNE-COVID, NCT04387253 Phase Not Applicable Not yet recruiting 1 14 Months 80 2020-05-18
Investigating the Role of Vitamin D in the Morbidity of COVID-19 Patients Coronavirus disease 19 infection vitamin D alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tameside Hospital NHS Foundation Trust UK 2020-06-01 2021-06-01 NCT04386044, TGH1234 Phase Not Applicable Not yet recruiting 1 12 Months 1000 Edward Jude, MD, Margaret Cooper, Rebecca Roberts 2020-05-18
Hydroxychloroquine prophylaxis in Covid 19 infection Coronavirus disease 19 infection, SARS coronavirus infection hydroxychloroquine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Indian Council of Medical Research India 2020-05-04 CTRI/2020/05/025010, HCQ Pro Study Protocol Version 1.3, Phase Not Applicable Status not specified 6 2000 Dr Atul gogia, Dr Dorairajan Sureshkumar, Dr Neeraj Agarwal, Dr Suneela Garg, Dr Vikas Bhatia, Madhavi Eerike, Pranab Chatterjee, Prof Pankaja Raghav, Suman Kanungo 2020-05-15
WHO SOLIDARITY Finland: A clinical study to evaluate the efficacy of different anti-viral drugs in SARS-CoV-2 infected patients (COVID-19) Coronavirus disease 19 infection hydroxychloroquine sulphate (Oxiklorin ) plus remdesivir Coronavirus non structural protein 8 modulator, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Clinical Urology and Epidemiology Working Group, University of Helsinki Finland 2020-04-29 2020-001784-88, WHO SOLIDARITY Finland, WHO-FIN-COVID-19 Phase 3 Clinical Recruiting 1 664 Dept. of Public Health 2020-05-18
An observational, retrospective study to evaluate hydroxychloroquine administration in patients with Covid-19 who had been admitted to the hospital Coronavirus disease 19 infection hydroxychloroquine alone New York State Department Of Health US Phase Not Applicable Status not specified 0 1446 2020-05-14
Evaluation of the effectiveness of rabbit antibody against coronavirus in patients Coronavirus disease 19 infection COVID-19 treatment alone, CoviGlobulin alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kowsar Biotechnology Co Iran 2020-05-21 IR.BMSU.REC.1399.110, IRCT20200508047346N1 Phase 3 Clinical Not yet recruiting 1 124 Dr. Mostafa Ghanei, Mahdi Behdani, Mostafa Ghanei, Sirous Zeinali 2020-05-15
LymphoCov1: Clinical Epidemiology and Characteristics Of Covid-19 Cases Occurred In A Lymphoma Setting In The First Epidemic Phase Coronavirus disease 19 infection, Lymphoma Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Versailles University Hospital France 2020-05-15 2020-07-15 LymphoCov1, NCT04386512, P20/12_LYMPHOCOV Phase Not Applicable Not yet recruiting 1 2 Months 50 Caroline Besson 2020-05-18
CATALYST: A randomized, phase II proof of principle multi-arm multi-stage trial designed to guide the selection of interventions for phase III trials in hospitalized patients with COVID-19 infection Coronavirus disease 19 infection Drug therapy alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The University of Birmingham United Kingdom Research & Innovation UK 2020-03-26 2021-05-01 2020-001684-89, CATALYST, CPMS 45648, IRAS 282431, ISRCTN40580903, RG_20-030 Phase 2 Clinical Recruiting 1 13 Months Dr Rowe 2020-05-18
Outcomes of viral infection in hematology patients Coronavirus disease 19 infection, Hematological disease Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Science and Engineering Research Board India 2020-05-28 CTRI/2020/05/025092 Phase Not Applicable Not yet recruiting 1 250 Biju George 2020-05-15
Knowledge status of public about COVID 19 disease prevention and control in Tamil Nadu Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Siddha Central Research Institute India 2020-05-20 CTRI/2020/05/025091 Phase Not Applicable Not yet recruiting 1 125 Dr C Anbarasi, Dr R Meena, Dr S Natarajan 2020-05-15
COVID MILK: COVID MILK Coronavirus disease 19 infection Emma Childrens Hospital Foundation Netherlands 2020-05-01 2020-06-30 COVID MILK, Trial NL8575 Phase Not Applicable Recruiting 1 2 Months 60 Johannes (Hans) B. van Goudoever 2020-05-15
COVUSd: COVID19 ultrasound diagnosis Coronavirus disease 19 infection ultrasound alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Isala Netherlands 2020-04-18 2020-06-01 COVUSd, Trial NL8544 Phase Not Applicable Recruiting 1 1 Month 50 Svenja Haak 2020-05-15
CVC for COVID-19: Charite Trial of Cenicriviroc (CVC) Treatment for COVID-19 patients Coronavirus disease 19 infection cenicriviroc alone, standard of care alone CCR2 chemokine antagonist, CCR5 chemokine antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Charite Universitaetsmedizin Berlin Germany 2020-05-11 2020-001493-29, CVC for COVID-19, CVC-for-COVID-19 Phase 2 Clinical Recruiting 1 200 Dept. of Hepatology and Gastroenter 2020-05-15
A randomized-controlled study to investigate the potential efficacy of monalizumab compared to standard of care against COVID-19 in cancer patients with mild symptoms Coronavirus disease 19 infection monalizumab alone NKG2 A B activating NK receptor antagonist Centre Leon Berard, Innate Pharma SA Phase Not Applicable Planned 0 2020-05-14
A randomized-controlled study to investigate the potential efficacy of avdoralimab compared to standard of care against COVID-19 in cancer patients with pneumonia Coronavirus disease 19 infection, Viral pneumonia avdoralimab (IPH5401) alone CXCR1 chemokine antagonist, Complement C5a receptor antagonist, IL-8 receptor antagonist, Monocyte chemotactic protein 1 ligand inhibitor Centre Leon Berard, Innate Pharma SA Phase Not Applicable Planned 0 2020-05-14
Low Dose Radiotherapy in COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia radiotherapy (0.5 Gy) alone, standard treatment alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shaheed Beheshti Medical University Iran 2020-05-04 2020-12-31 23568, IR.SBMU.RETECH.REC.1399.073, IRCT20200509047366N1, NCT04390412 Phase 1/Phase 2 Clinical Recruiting 2 7 Months 5 Ahmad Ameri, Ahmad Ameri, Prof., Imam Hossein Hospital, Nazanin Rahnama, M.D. 2020-05-18
MPN-COVID: Myeloproliferative Neoplasms (MPN) and COVID-19 Coronavirus disease 19 infection, Myelofibrosis, Polycythemia, Polycythemia vera Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fondazione per la Ricerca Ospedale Maggiore European Leukemia Net Denmark, Italy, Spain, France, UK, Germany 2020-05-01 2020-09-01 FROM - O-MPN-COVID-2020, MPN-COVID, NCT04385160 Phase Not Applicable Not yet recruiting 39 4 Months 80 Alessandra Carobbio, BioStat, Alessandra Iurlo, Alessandro Maria Vannucchi, Andrea Patriarca, Arianna Masciulli, PharmD, Chiara Paoli, Claire Harrison, Clara De Ambrogi, Daniele Vanni, Denise Soldati, Elena Elli, Elena Rossi, Elisa Rumi, Emilia Florea, Fabrizio Cavalca, Francesca Pirillo, Giulia Benevolo, Giulia Desa, Giuseppe Rossi, Hans Carl Hasselbalch, Ida Martinelli, Ilaria Nichele, Jean-Jacques Kiladjian, Luigi Scaffidi, Marco Ruggeri, Massimiliano Bonifacio, Monia Marchetti, Paola Guglielmelli, Rosa Daffini, Rosalba Sciancalepore, Silvia Artuso, Silvia Betti, Stefania Priolo, Steffen Koschmieder, Valerio De Stefano 2020-05-14
Evaluating the effect of intravenous hydrocortisone, methylprednisolone, and dexamethasone in treatment of patients with moderate to severe acute respiratory distress syndrome caused by COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome dexamethasone alone, hydrocortisone alone, methylprednisolone alone, routine care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hamadan University of Medical Sciences Iran 2020-06-04 IR.UMSHA.REC.1399.152, IRCT20120215009014N354 Phase 2 Clinical Not yet recruiting 1 81 Dr Abbas Taher, Dr. Fariba Keramat, Dr. Jalal Poorolajal, Dr. Saeid Bashirian 2020-05-15
COSiN: Collection of Coronavirus COVID-19 Outbreak Samples in New South Wales Coronavirus disease 19 infection blood sampling alone National Centre in HIV Epidemiology and Clinical Research Australia 2020-05-06 2021-06-30 COSiN, NCT04383652, VISP2005 Phase Not Applicable Recruiting 9 13 Months 200 Adam Bartlett, Angie Pinto, Bernard Hudson, Gail Matthews, Jeffrey Post, Marianne Martiello, Marianne Martinello, Michael Mina, Nicky Gilroy, Rowena Bull, William Rawlinson 2020-05-14
A global study to evaluate the safety, tolerability and efficacy of the immunoglobulin therapy (COVID-19), CoVIg-19 Plasma Alliance in adult patients with COVID-19 Coronavirus disease 19 infection anti-SARS-CoV-2 polyclonal hyperimmune immunoglobulin therapy (COVID-19), CoVIg-19 Plasma Alliance/ Takeda/ CSL Behring alone CoVIg-19 Plasma Alliance, National Institute of Allergy and Infectious Diseases Phase Not Applicable Planned 0 2020-05-14
COVIDAge Study: Outcomes in Hospitalized Older Patients With COVID-19 Coronavirus disease 19 infection Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopitaux Universitaires De Geneve Switzerland 2020-03-13 2020-04-14 2020-00819, COVIDAge Study, NCT04385212 Phase Not Applicable Completed 1 1 Month 230 Christine Serratrice 2020-05-15
A phase I clinical study of COVID-19 vaccine (measles vaccine vector technology), Institut Pasteur/Themis Bioscience/University of Pittsburgh for the potential prevention of COVID-19 infection Coronavirus disease 19 infection COVID-19 vaccine (measles vaccine vector technology), Institut Pasteur/Themis Bioscience/University of Pittsburgh alone Themis Bioscience GmbH ABL Europe Phase 1 Clinical Planned 0 2020-05-14
MASC- study: Metabolic syndrome And Severity of Covid-19 Coronavirus disease 19 infection, Metabolic syndrome X Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sint Franciscus Gasthuis Netherlands 2020-04-28 2020-06-01 2020-041, MASC- study, NL8580 Phase Not Applicable Recruiting 1 1 Month 100 Cathelijne van Zelst 2020-05-18
TBA: Lung ultrasound findings in patients with novel SARS CoV2 Coronavirus disease 19 infection lung ultrasound alone Amsterdam UMC Netherlands 2020-03-26 2020-04-23 FWA00017598, NL8540, TBA Phase Not Applicable No longer recruiting 1 50 Mark Haaksma 2020-05-15
COVID KIDS: Humoral responses to SARS-CoV-2 infection in children Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Emma Children’s Hospital Netherlands 2020-04-12 2021-04-04 COVID KIDS, NL73556.018.20, NL8531 Phase Not Applicable Recruiting 1 11 Months 420 Dasja Pajkrt 2020-05-17
Malaysian COVID-19 Anosmia Study (Phase II) - A Nation-wide, Multicenter, Case-Control Study Coronavirus disease 19 infection, Dysomia Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sultanah Bahiyah Hospital HOSPITAL RAJA PEREMPUAN ZAINAB II, Hospital Enche' Besar Hajjah Khalsom, Hospital Kuala Lumpur, Hospital Permai, Hospital Queen Elizabeth, Hospital Raja Permaisuri Bainun, Hospital Sultan Ismail, Hospital Sultanah Maliha, Hospital Sungai Buloh, Hospital Tengku Ampuan Afzan, Hospital Tuanku Fauziah, Melaka Hospital, Pulau Pinang Hospital, Sarawak General Hospital, Sultanah Aminah Hospital, Sultanah Nur Zahirah Hospital, Tuanku Jaafar Hospital Malaysia 2020-05-31 2020-08-31 MCO-002, NCT04384042 Phase 2 Clinical Not yet recruiting 18 3 Months 60 Amran Mohamad, MD MS, Anilawati Mat Jelani, MD MMed, Chee Loon Leong, MBBS MMed, Chenthilnathan Periasamy, MBBS MMed, Chun Yiing Wong, MBBS MMed, Dzawani Muhamad, MD MMed, Elang Kumaran Krishnan, MBBS MS, Fadzilah Ismail, MD MS, Halimuddin Sawali, MBBS MS, Heng Gee Lee, MBChB MRCP, Ibtisam Ismail, BSc, Ida Sadja'ah Sachlin, MBBS MMed, Jeyasakthy Saniasiaya, MMed FEBORL, Jothi Shanmuganathan, MBBS MMed, Kuldip Kaur Prem Kaur, MBBS MPH, Lee Lee Low, MD MRCP, Linda Pei Fang Lim, MD MS, Mahiran Mustafa, MBBCh MMed, Masliza Zaid, MBBS MMed, Mohd Noor Ismail, MD MRCP, Mohd Zambri Ibrahim, MD MMed, Nor Zaila Zaidan, MD MMed, Norzi Gazali, MBBS MMed, Philip Rajan Devesahayam, MMed FRCS, Rosdi Ramli, MBBS MMed, Shahrul Aiman Soelar, B Ind Stats, Sharifah Baizura Syed Alwi, MD MRCPI, Shen-Han Lee, MB PhD MRCS, Siti Sabzah Hashim, MD MS, Siti Sabzah Mohd Hashim, MD MS, Sobani Din, MD MS, Suhaila Abd Wahab, MBBS MMed, Suhaimi Yusof, MBBS MMed, Suhaimi Yusuf, MBBS MMed, Tengku Mohamed Izam Tengku Kamalden, MS FRCS, Tiang Koi Ng, MBBS MRCP, Ting Soo Chow, MD MRCP, Zhi Xiang Yeoh, MBBS MS MRCS, Zulkiflee Salahuddin, MD MS 2020-05-17
ICOS: International SARS-CoV-2 (COVID-19) Infection Observational Study Coronavirus disease 19 infection, Dyspnea biological sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Minnesota National Institute of Allergy and Infectious Diseases, National Institutes of Health Argentina, UK, US, Denmark 2020-05-15 2021-06-30 75N91019D00024, ICOS, ICOS, NCT04385251 Phase Not Applicable Not yet recruiting 3 13 Months 10000 Edward Gardner, Eileen Denning, James Neaton, PhD, Jens Lundgren, Sarah Pett 2020-05-14
COVIDNA: Pre-exposure Prophylaxis With Hydroxychloroquine in Sanitaries Highly Exposed to COVID-19 Coronavirus disease 19 infection, Viral pneumonia hydroxychloroquine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Fundación Pública Miguel Servet Instituto de Salud Carlos III Spain 2020-04-23 2020-001697-30, COVIDNA, COVIDNA Phase 3 Clinical No longer recruiting 1 200 RUTH GARCÍA 2020-05-14
Lung ultrasound and computed tomography for monitoring SARS-CoV-2 in critical care departments Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia Lung ultrasound monitoring alone, computed tomography monitoring alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Amsterdam UMC 2020-03-27 2020-05-10 NL8584 Phase Not Applicable Recruiting 0 1 Month 80 Micah Heldeweg 2020-05-15
Validation of 3D nasopharyngeal swab Coronavirus disease 19 infection 3D nasopharyngeal swab validation alone Universiti Sains Islam Malaysia Malaysia 2020-05-18 2020-11-19 54849, NMRR-20-879-54849 Phase Not Applicable Not yet recruiting 1 6 Months 30 Dr Nor Eyzawiah Binti Hassan, Dr SITI ASMAT BINTI MD AREPEN 2020-05-14
COH-FIT: Collaborative Outcomes Study on Health and Functioning During Infection Times During COVID-19 Pandemic Coronavirus disease 19 infection Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Padova Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health Inc Greece 2020-04-26 2022-06-30 COH-FIT, COH-FIT, NCT04383470 Phase Not Applicable Recruiting 1 26 Months 100000 Agorastos Agorastos, Agorastos Agorastos, MD, Andres Estradè, MSc, Christoph U. Correll, MD, Marco Solmi, MD 2020-05-15
BEAT-COVID1: Biomarker-based Early Anti-inflammatory Therapy for severe COVID-19 Coronavirus disease 19 infection, Lung injury, Multiple organ failure Anti-inflammatory Therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Leiden University Medical Center Netherlands 2020-04-24 2020-09-30 BEAT-COVID1, METC LDD P20.046, NL8589 Phase Not Applicable Recruiting 1 5 Months 250 Anna Roukens, Dr. L.G. Visser 2020-05-18
RISC: Role of Ibuprofen and Other Medicines on Severity of Coronavirus Disease 2019 Coronavirus disease 19 infection University Hospital, Bordeaux Bordeaux PharmacoEpi France 2020-05-11 2020-07-31 CHUBX 2020/13, NCT04383899, RISC Phase Not Applicable Not yet recruiting 9 2 Months 200 Alexandre BOYER, Pr, Anne-Marie LEROI, Pr, Denis MALVY, Pr, Didier GRUSON, Pr, Duc NGUYEN, Dr, Florentia KAGUELIDOU, Dr, Jean-Jacques KILADJIAN, Pr, Jean-Luc CRACOWSKI, Pr, Jean-Sébastien HULOT, Pr, Marc BARDOU, Pr, Nicholas MOORE, Pr, Patrick BLIN, Dr, Rachel FROGET, Dr 2020-05-14
Fear Among Dentists During COVID-19 Pandemic Anxiety disorder, Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cairo University Egypt 2020-03-02 2020-05-05 COVID-19 PANDEMIC, NCT04383626 Phase Not Applicable Completed 1 2 Months 216 2020-05-14
'Investigation of the Relationship Between New Coronary Virus Disease (COVID-19) and Anxiety and Depressive Symptoms in Pregnant Women' Anxiety disorder, Coronavirus disease 19 infection, Depression Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Istanbul Bakirkoy Maternity and Children Diseases Hospital Turkey 2020-04-25 2020-07-26 BECKCOVID, NCT04384887 Phase Not Applicable No longer recruiting 1 3 Months 100 Pınar Yalcin bahat 2020-05-14
Covid-19 Triage Using Camera-based AI Coronavirus disease 19 infection RIA-device (Remote Investigation and Assessment) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Vastra Gotaland Region Detectivio Ab Sweden 2020-05-31 2020-12-31 NCT04383457, U1111-1251-4114 Phase Not Applicable Not yet recruiting 1 7 Months 500 Ronny K Gunnarsson, MD PhD, Stefan Malmberg, MD 2020-05-14
Efficacy and Tolerability of Hydroxychloroquine in Adult Patients With COVID-19 Coronavirus disease 19 infection, Viral pneumonia, Viral respiratory tract infection Plaquenil alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Taoyuan General Hospital Center For Disease Control Department Of Health Taiwan Roc, Center for Drug Evaluation, Taiwan, National Health Research Institutes, Taiwan Food and Drug Administration Taiwan 2020-04-01 2020-09-30 NCT04384380, TYGH109014 Phase 4 Clinical Recruiting 1 6 Months 45 Chien-Yu Cheng, Dr., Jang-bin Chen, Dr., Shu-Hsing Cheng, Dr., YUNG-NIEN HSU, Dean, Yi-Chun Lin, Dr. 2020-05-14
Surveillance of Individuals Following SARS-CoV-2 Exposure Coronavirus disease 19 infection antibody assays alone, reverse transcription-polymerase chain reaction (RT-PCR) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Allergy and Infectious Diseases National Institutes of Health Clinical Center US 2020-05-22 2023-06-16 20-I-0117, 200117, NCT04383444 Phase Not Applicable Recruiting 0 36 Months 1050 Lisa A Barnhart, R.N., Steven M Holland, M.D. 2020-05-20
Outcome of COVID-19 Patients After Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome Coronavirus disease 19 infection, Respiratory distress syndrome extracorporeal membrane oxygenation therapy alone Karolinska University Hospital HELSINKI UNIVERSITY HOSPITAL Finland, Italy, UK, Sweden, Germany, France 2020-03-01 2020-12-31 COVID-19 ECMO, NCT04383678 Phase Not Applicable Recruiting 11 10 Months 200 Andrea Perrotti, Antonio Fiore, Antonio Loforte, Enrico Leo, Fausto Biancari, Fausto Biancari, Professor, Giovanni Mariscalco, Henryk Welp, Lars M Broman, Magnus Dalen, Magnus Dalen, Assoc prof, Magnus Dalén, Nicla Settembre, Svante Zipfel, Vito G Ruggieri 2020-05-19
A randomized controlled trial of hydroxychloroquine prophylaxis for Healthcare Workers exposed to COVID-19 Coronavirus disease 19 infection hydroxychloroquine alone, standard care Personal protective equipment alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) George Institute for Global Health India India 2020-06-15 CTRI/2020/05/025067 Phase 2 Clinical Not yet recruiting 3 10990 Dr Bala Venkatesh, Dr Bharath Kumar, Professor Vivekanand Jha 2020-05-15
COVER-PRO: Evaluation of Emergency Department (ED) Staff Stress Level During COVID-19 Pandemic Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection stress and anxiety questionnaire alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospices Civils De Lyon France 2020-04-18 2020-08-18 69HCL20_0330, COVER-PRO, NCT04383886 Phase Not Applicable Recruiting 5 4 Months 200 Guillaume DURAND, MD, Julien BERTHILLER, Karim TAZAROURTE, MD, Laurent JACQUIN, MD, Marion DOUPLAT, MD, Vanessa LABEYE, MD 2020-05-14
GERONIMO 19: Study of the Efficiency of Normal Human Immunoglobulins (Ivig) in Patients Aged 75 Years and over Covid-19 with Severe Acute Respiratory Failure Coronavirus disease 19 infection, Respiratory failure polyvalent intravenous immunoglobulin alone, tandard management alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Hospital, Versailles France 2020-04-27 2020-001768-27, GERONIMO 19, P20/07 Phase 2 Clinical Recruiting 1 Mélody FORT 2020-05-14
Randomized controlled trial of an app-based intervention, Anchored, to support the mental health of Australians recently unemployed due to COVID-19 Coronavirus disease 19 infection Anchored app alone, mindfulness exercises alone, psychoeducational videos alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Australian Government Department of Health and Ageing Australia 2020-06-01 2020-12-30 ACTRN12620000555954 Phase Not Applicable Not yet recruiting 1 6 Months 492 Dr Mark Deady 2020-05-19
SINUS WASH: Sinus-Wash Pilot Study Coronavirus disease 19 infection betadine alone, vedine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hampshire Hospitals NHS Foundation Trust UK 2020-05-01 2020-001721-31, SINUS WASH, SPON-AK-0420 Phase 2 Clinical Recruiting 1 40 Chief Investigator 2020-05-14
RECOVER: A Randomized, Open-label, Phase-II Clinical Trial with or without Infusion of Plasma from Subjects after Convalescence of SARS-CoV-2 Infection in High-Risk Patients with Confirmed Severe SARS-CoV-2 Disease Coronavirus disease 19 infection convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Heidelberg German Federal Ministry of Education and Research Germany 2020-04-05 2020-001632-10, EudraCT-N° 2020-001632-10, RECOVER, SARS-CoV-2CP-HD-001 Phase 2 Clinical Recruiting 1 174 Prof. Dr. Carsten Müller-Tidow 2020-05-14
COVID-19 Prophylaxis With Hydroxychloroquine Associated With Zinc For High-Risk Healthcare Workers Coronavirus disease 19 infection hydroxychloroquine plus zinc sulfate Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Nucleo De Pesquisa E Desenvolvimento De Medicamentos Da Universidade Federal Do Ceara Federal University of Ceara Brazil 2020-05-31 2020-10-31 HCQZN, NCT04384458 Phase 2 Clinical Not yet recruiting 1 5 Months 400 A, Elisabete A Moraes (betemora), Elisabete A Moraes, Professor 2020-05-14
ALLIANCE: International ALLIANCE Study of Therapies to prevent progression of COVID-19, a randomized trial Coronavirus disease 19 infection Variable regimens including Vit B12 , Vit D3 , Vitamin C , azithromycin , hydroxychloroquine , zinc Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rinehart Medical Foundation National Institute of Integrative Medicine Australia, US 2020-05-18 2021-06-30 ACTRN12620000557932p, ALLIANCE Phase 2 Clinical Not yet recruiting 2 13 Months 200 A/Prof Karin Ried 2020-05-14
ADAPT: COVID-19 Study - A prospective, observational cohort study at St Vincent’s Hospital Sydney Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) St Vincents Hospital Sydney Ltd Australia 2020-05-14 2022-05-31 ACTRN12620000554965, ADAPT Phase Not Applicable Not yet recruiting 1 24 Months 300 A/Prof Gail Matthews 2020-05-14
VICTORIA: VICTORIA Coronavirus disease 19 infection, Viral pneumonia itolizumab alone T-cell differentiation antigen CD6 inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The Center of Molecular Immunology Cuba 2020-03-28 2020-07-31 IIC RD-EC 179, RPCEC00000311, VICTORIA Phase 2 Clinical Recruiting 5 4 Months 80 Armando Caballero Lopez, Crombet Ramos, Mayra Ramos-Suzarte 2020-05-18
Evaluation of the safety and efficacy of BIOMODULINA T for the prevention of infections, including COVID-19, in older adults in Cuba. Phase IV clinical trial (COVID-19) Coronavirus disease 19 infection Biomodulina T alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Biopreparations Center Cuba 2020-04-03 2020-07-30 GEC2020BMT024, RPCEC00000310 Phase 4 Clinical Recruiting 1 3 Months Macias Abraham, Reyes Zamora, Rodriguez Rivera 2020-05-18
Organicell Flow for Patients With COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome Organicell flow alone, standard care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Organicell Regenerative Medicine US 2020-05-31 2020-12-31 19881, NCT04384445 Phase 1 Clinical Not yet recruiting 0 7 Months 20 George C Shapiro, MD, Maria I Mitrani, MD, PhD, Maria I Mitrani, MD. PhD, William Kapp, MD 2020-05-14
Accelerated iTBS for Depressed Patients During the COVID-19 Pandemic Coronavirus disease 19 infection, Major depressive disorder, Psychotic disorder B70 Fluid-Cooled Coil alone, MagPro X100 stimulator alone, accelerated intermittent theta burst stimulation alone, relapse prevention treatment alone, virtual check-in alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre for Addiction and Mental Health Canada 2020-05-01 2022-11-01 059/2020, NCT04384965 Phase Not Applicable Recruiting 1 30 Months 200 Daniel Blumberger, MD, Mawahib Semeralul, Nicole Schoer 2020-05-15
Health and Wellbeing of Pregnant and Post-Partum Women During the COVID-19 Pandemic Coronavirus disease 19 infection online survey alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Pregistry Harvard TH Chan School of Public Health US 2020-05-15 2020-08-31 0002, NCT04385238 Phase Not Applicable Recruiting 0 3 Months 2500 Diego Wyszynski, MD, MHS, PhD, Karestan Koenen, PhD, Sonia Hernandez-Diaz, MD, DrPH, Sonia Hernandez-Diaz, MD, DrPh 2020-05-20
TX-COVID19: TX-COVID19 Coronavirus disease 19 infection Nebulization alone, Homeostec plus Paracetamol Cancerology State Institute, Colima State Health Services, Universidad de Colima Mexico 2020-05-20 2021-01-15 RPCEC00000309, TX-COVID19 Phase 1/Phase 2 Clinical Not yet recruiting 1 7 Months 50 Delgado Enciso, Paz Garcia 2020-05-18
COV2-CP: Hyperimmune Plasma in Patients With COVID-19 Severe Infection Coronavirus disease 19 infection plasma hyperimmune therapy alone, standard therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Universita' Degli Studi "Magna Graecia" Di Catanzaro Azienda Ospedaliera Bianchi Melacrino Morelli, Azienda Ospedaliera Universitaria Mater Domini di Catanzaro, Azienda Sanitaria Provinciale Di Catanzaro, Hospital of Cosenza Italy 2020-05-01 2021-05-15 COV2-CP, COVID-19 CONVALESCENT PLASMA, NCT04385043 Phase 2/Phase 3 Clinical Recruiting 6 12 Months 400 Alfonso Trimarchi, MD, Andrea Dominijanni, MD, Carlo Torti, MD, Federico Longhini, MD, Francesco Zinno, MD, Gabriella Talarico, MD, Giovanni Matera, MD, Luca Gallelli, Lucio Cosco, MD, Maria Laura Guzzo, MD, Paola Grandini, MD, Pasquale Minchella, MD, Patrizia Leonardo, MD, Piero Gangemi, MD 2020-05-14
ISCA: Inhaled Sedation in COVID-19-related Acute Respiratory Distress Syndrome (ISCA): an International Research Data Study in the Recent Context of Widespread Disease Resulting From the 2019 (SARS-CoV2) Coronavirus Pandemics (COVID-19) Coronavirus disease 19 infection, Respiratory distress syndrome Inhaled sedation alone, Intravenous sedation alone, isoflurane alone, sevoflurane alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Clermont-Ferrand Groupe Hospitalier Pitie-Salpetriere, University of Valencia, Universitätsklinikum Schleswig-Holstein France, Germany, Spain 2020-05-31 2020-12-31 ISCA, ISCA STUDY, NCT04383730 Phase Not Applicable Not yet recruiting 6 7 Months 400 Caroline Varillon, Jean-Michel Constantin, Lise Laclautre, Matthieu Jabaudon, Pierre Boucher, Rafael Badenes 2020-05-14
ACTT 2: A randomized, controlled clinical trial evaluating the safety and efficacy of a remdesivir plus baricitinib for coronavirus disease 2019 (COVID-19) Coronavirus disease 19 infection baricitinib plus remdesivir Coronavirus non structural protein 8 modulator, Jak1 tyrosine kinase inhibitor, Jak2 tyrosine kinase inhibitor, RNA polymerase modulator National Institutes of Health National Institute of Allergy and Infectious Diseases US 2020-05-08 ACTT 2 Phase Not Applicable Recruiting 0 2020-05-19
StayHome: Early Hydroxychloroquine to Reduce Secondary Hospitalization and Household Transmission in COVID-19 Coronavirus disease 19 infection hydroxychloroquine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Lausanne Switzerland 2020-05-12 2020-10-31 NCT04385264, StayHome, UNISANTE Phase 2/Phase 3 Clinical Not yet recruiting 1 5 Months 800 Alix Miauton, MD, Blaise Genton, MD-PhD, Jacques Cornuz, MD-PhD, Mary-Anne Hartley, MD, PhD MPH, Mary-Anne Hartley, MD, PhD, MPH, Valérie D'Acremont, MD-PhD 2020-05-15
Covid-19 Pandemic: Patients Experience in T1D Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression, Diabetic ketoacidosis, Hypoglycemia, Insulin dependent diabetes Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) McGill University Canadian Institutes of Health Research, Juvenile Diabetes Research Foundation Canada 2020-04-29 2021-01-01 2021-1079, NCT04384471 Phase Not Applicable Recruiting 1 8 Months 384 Anne-Sophie Brazeau, PhD 2020-05-15
Familles-COVID: Psychological Impact of the Hospitalization of a Family Member in Intensive Care for Covid-19 Infection Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopitaux Universitaires de Strasbourg France 2020-05-31 2021-02-28 7761, Familles-COVID, NCT04385121 Phase Not Applicable Not yet recruiting 1 9 Months 60 Ferhat MEZIANI, Julie HELMS 2020-05-14
Safety and Immunogenicity Study of Inactivated Vaccine for Prevention of SARS-CoV-2 Infection (COVID-19) Coronavirus disease 19 infection Inactivated vaccine (COVID-19), Sinovac Biotech alone Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sinovac Research & Development Co Ltd China 2020-05-20 2020-07-20 NCT04383574, PRO-NCOV-1002 Phase 1/Phase 2 Clinical Not yet recruiting 1 2 Months 422 Hui Jin, Yuliang Zhao, Master 2020-05-18
Rapid Detection 2019-nCOV via Surface Plasamon Resonance Coronavirus disease 19 infection RT-PCR method alone, Surface Plasamon Resonance method alone Southeast University, The Affiliated Zhongda Hospital of Southeast University National Natural Science Foundation of China China 2020-05-25 2021-03-19 ChiCTR2000032842 Phase 0 Clinical Not yet recruiting 1 9 Months 400 Wenjing Xu, Yewei Zhang 2020-05-14
The Geneva Covid-19 CVD Study Acute coronary syndrome, Cardiac failure, Coronavirus disease 19 infection, Heart arrhythmia, Myocarditis Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopitaux Universitaires De Geneve Switzerland 2020-03-24 2022-03-31 CCER-2020-00610, NCT04384029 Phase Not Applicable No longer recruiting 1 24 Months 7000 Francois MACH 2020-05-15
Inactivated Convalescent Plasma as a Therapeutic Alternative in Patients CoViD-19 Coronavirus disease 19 infection, Respiratory distress syndrome, Sepsis, Septic shock, Viral pneumonia inactivated convalescent plasma alone, support treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Blood Center Foundation, Hemolife Universidad de Antioquia Colombia 2020-05-20 2020-11-30 CT01, NCT04385186 Phase 2 Clinical Not yet recruiting 10 6 Months 60 Amanda E Maestre, MD, PhD, Ana L Muñoz, MSc, PhD, Andrés F Zuluaga, MD, MSc, MeH, Carlos A Arbélaez, MD, MSc, Daniel C Aguilar, MSc, PhD, Diego Gómez, MD, MSc, Diego Gómez, MD, Msc, Diego Gómez, MD. MSc, Fabian H Muñoz, MD, MSc, Harold Alvaréz, MD, MSc, Juan C Calderon, MD, MSc, Miguel G Rueda, MD, MSc 2020-05-20
COVIDBioToul: Predictive Immune Biomarkers for COVID-19 Pathogenesis Coronavirus disease 19 infection, Respiratory distress syndrome blood collection alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire de Toulouse France 2020-05-12 2021-12-31 COVIDBioToul, NCT04385108, RC31/20/0162 Phase Not Applicable Not yet recruiting 1 19 Months 170 Guillaume MARTIN-BLONDEL, MD PhD 2020-05-14
COV-HI: COVID-19 Hyperinflammation Syndrome (COV-HI): Protocol for a Rapidly Executed Cohort Study Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University College London Newcastle Upon Tyne Hospitals NHS Trust, Nottingham University Hospital, Sheffield Teaching Hospitals NHS Foundation Trust, The Leeds Teaching Hospitals NHS Trust, England, University College London Hospital UK 2020-04-16 2020-07-05 132388, COV-HI, NCT04385069 Phase Not Applicable Recruiting 5 2 Months 500 Amanda Ledlie, Jessica Manson, Dr, Joe West, Prof., Matthew Collin, Prof., Rachel Tattershall, Sinisa Savic 2020-05-14
Genetic Basis of COVID-19 Infection Coronavirus disease 19 infection whole exome sequencing alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Mansoura University Egypt 2020-05-10 2021-05-01 NCT04384250, RP:20.05.70 Phase Not Applicable Recruiting 1 11 Months 50 Ali Sobh, Ali Sobh, MD, Marwa Elnagdy, MD 2020-05-14
FALP-COVID: COVID-19-Convalescent Plasma for Treating Patients With Active Symptomatic COVID-19 Infection Coronavirus disease 19 infection convalescent plasma alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Arturo Lopez Perez Foundation Bolsa de Santiago, Confederation for Production and Commerce of Chile (CPC) Chile 2020-04-07 2021-04-06 FALP 001-2020, FALP-COVID, NCT04384588 Phase 2/Phase 3 Clinical Recruiting 1 12 Months 100 Christian Caglevic, MD, Christian Caglevic, md, Raimundo Gazitua, MD 2020-05-14
A clinical trial to study the efficacy of homeopathic medicine in prevention and cure of Coronavirus disease 19 Coronavirus disease 19 infection arsenic album 30 alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Sai Nidan Homeopathic Clinic India 2020-05-08 CTRI/2020/05/025049 Phase 2/Phase 3 Clinical Not yet recruiting 1 100 DR ASHISH DUBEY, DR DHIRENDRA TIWARI 2020-05-14
Levamisole and Isoprinosine in the Treatment of COVID-19: A Proposed, Therapeutic Trial Coronavirus disease 19 infection isoprinosine plus levamisole Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cairo University Egypt 2020-05-05 2020-10-30 LEVAMISOLE AND ISOPRINOSINE, NCT04383717 Phase 3 Clinical Not yet recruiting 1 5 Months 60 Hagar El Sayed, Hagar El Sayed, MD, Mohamed El Darouti, Professor 2020-05-14
POCUS: Predicting Outcomes for Covid-19 Using Sonography Coronavirus disease 19 infection, Viral pneumonia lung ultrasound alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Stanford University US 2020-03-21 2020-12-31 IRB-55621, NCT04384055, POCUS Phase Not Applicable Recruiting 0 9 Months 200 Andre D Kumar, MD, MEd 2020-05-14
H-Cov-Run: HDL Target of COVID-19 ? Analysis on the Caregivers of the Reunion University Hospital Coronavirus disease 19 infection blood sampling alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire de la Réunion France 2020-05-31 2021-06-30 2020/CHU/08, H-Cov-Run, NCT04384705 Phase Not Applicable Not yet recruiting 1 13 Months 500 David COURET, PH, Lucie AUZANNEAU 2020-05-14
CovidSurg-Cancer: Outcomes of Elective Cancer Surgery During the COVID-19 Pandemic Crisis Breast tumor, Colorectal tumor, Coronavirus disease 19 infection, Esophagus tumor, Gynecological disorder, Liver tumor, Pancreas tumor, Sarcoma, Stomach tumor, Urinary tract tumor elective cancer surgery alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The University of Birmingham Christian Medical College and Hospital Pakistan, Philippines, US, Ghana, Zambia, South Africa, India, UK, United Arab Emirates, Canada, Australia, Spain, Nigeria, Mexico, France, Italy, Benin, Rwanda 2020-03-30 2020-12-31 CSC-20200324, CTRI/2020/05/025160, CovidSurg-Cancer, NCT04384926 Phase Not Applicable Recruiting 23 9 Months 1000 Ana Minaya-Bravo, Aneel Bhangu, Arshad Rashid, Asif Mehraj, Dhruva Nath Ghosh, Dmitri Nepogodiev, Parvez David Haque, Rohin Mittal, Shyla Sree, Stanley Mathew, Vijay Pillai 2020-05-15
CoVideo: A short, animated video to improve COVID-19 hygiene uptake: an online randomized experiment with 20,000 participants Coronavirus disease 19 infection CoVideo alone, attention placebo control (PAC) video alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) University of Heidelberg Heidelberg Institute of Global Health, Stanford University Spain, France, US, UK, Germany, Mexico 2020-05-31 55820, CoVideo, DRKS00021582 Phase Not Applicable Not yet recruiting 5 20000 Alain Vandormael, Mr. Dr Till Barnighausen, Mr. Prof Dr Till Baernighausen, Ms. Dr Maya Adam 2020-05-14
CONNAITRE: COVID-19 In Tunisia: An Observational, Cross-Sectional, Registry Study Coronavirus disease 19 infection PCR test alone, TDR test alone, clinical examination alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ministère de la Santé Abderrahmane Mami Hospital, Dacima Consulting, Eshmoun Clinical Research Centre Tunisia 2020-05-15 2020-07-15 CONNAITRE, ECC2020-07, NCT04384614 Phase Not Applicable Not yet recruiting 1 2 Months 400 Agnès Hamzaoui, Pr, Chokri Jeribi, Dr, Eshmoun Clinical Research Centre 2020-05-14
Advanced Endoscopy During COVID-19 Coronavirus disease 19 infection, Gastrointestinal disease endoscopic retrograde cholangiopancreatography alone, endoscopic ultrasound alone Al-Azhar University Helwan University, National Liver Institute, Egypt Egypt, Singapore, US 2020-05-15 2020-09-01 GLOBAL-ENDO-COVID, NCT04385147 Phase Not Applicable Not yet recruiting 2 3 Months 250 Damien Tan, MBBS, MRCP, Mohamed Alboraie, MD, MRCP(UK), Shahzad Iqbal, MD 2020-05-14
PR-Covid-19: Clinical, Biological and Histological Pulmonary and Renal Damage Associated With the SARS-CoV-2 Syndrome in Patients Admitted in ICU Adult respiratory distress syndrome, Coronavirus disease 19 infection, Lung injury, Renal failure Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopitaux Universitaires de Strasbourg France 2020-04-27 2020-07-31 7815, NCT04385004, PR-Covid-19 Phase Not Applicable Recruiting 1 3 Months 320 Alexandra MONNIER, MD, Bruno MOULIN, MD, PhD, Ferhat MEZIANI, MD, PhD, Francis SCHNEIDER, MD, PhD, François SEVERAC, MD, Hamid MERDJI, MD, Julie HELMS, MD, Margaux DELLA CHIESA, MD, Michel MERTES, MD, PhD, Patrick OHLMANN, MD, PhD, Romain KESSLER, MD, PhD, Saïd CHAYER, PhD, HDR, Sophie CAILLARD, MD, PhD 2020-05-14
Convalescent Plasma for Patients With COVID-19 Coronavirus disease 19 infection, Dyspnea convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Henry Ford Health System US 2020-05-04 2020-08-01 13807, NCT04385199 Phase 2 Clinical Recruiting 0 2 Months 30 Geneva Tatem, MD 2020-05-15
CoV-ICU Score, Intensive Care Unit, SARS-CoV-2 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bursa Yüksek İhtisas Eğitim Ve Araştırma Hastanesi Turkey 2020-06-01 2020-08-31 BYIEAH-202005, NCT04383483 Phase Not Applicable Not yet recruiting 1 3 Months 100 Ali ASAN, Associate professor, Ali Asan, MD, Erkan Sayan, MD 2020-05-14
Caards-1: Curosurf in Adult Acute Respiratory Distress Syndrome Due to COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia Curosurf alone, bronchial fibroscopy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Versailles University Hospital France 2020-05-04 2021-01-30 2020-001598-66, Caards-1, NCT04384731, P20/06 Phase 2 Clinical Recruiting 1 8 Months 20 Christophe LENCLUD, MD, Sandrine ROUX 2020-05-14
HYDROCYCLO: Clinical Study In Which Patients Are Randomized To Receive Hydroxychloroquine versus Cyclosporine - Hydroxychloroquine To Compare Their Efficacy In The Treatment Of COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia ciclosporin, Novartis plus hydroxychloroquine Calcineurin inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Infanta Sofia Spain 2020-05-07 2020-002123-11, HUIS-04-2020, HYDROCYCLO Phase 4 Clinical Recruiting 1 280 Gemma María Mora Ortega, Gonzalo Serralta San Martín, Tatiana Cobo Ibañez 2020-05-14
Convalescent Plasma for Treatment of COVID-19: An Exploratory Dose Identifying Study Coronavirus disease 19 infection SARS-CoV-2 convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Karolinska University Hospital Danderyd Hospital, Karolinska Institutet Sweden 2020-05-07 2020-12-31 CP2, NCT04384497 Phase 1/Phase 2 Clinical Recruiting 2 7 Months 50 Joakim Dillner, Joakim Dillner, MD, PhD, Johan Ursing, MD, PhD, Karl Hagman, MD 2020-05-14
Neuromuscular Electrical Stimulation in Patients With COVID-19 Associated Pneumonia Coronavirus disease 19 infection, Viral pneumonia Neuromuscular Electrical Stimulation alone, Routine physical therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Turin Azienda Ospedaliero Universitaria San Luigi Gonzaga Italy 2020-04-17 2020-07-31 ESC270320, NCT04382729 Phase Not Applicable Recruiting 1 3 Months 80 Chiara Busso, MD, Federica Gamna, MD, Marco Alessandro Minetto, MD, PhD, Sabrina Dal Fior, MD 2020-05-14
ELVIS COVID-19: Hypertonic Saline Nasal Irrigation and Gargling in Suspected or Confirmed COVID-19 Coronavirus disease 19 infection hypertonic saline nasal irrigation and gargling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Edinburgh UK 2020-05-01 2020-07-31 AC20042, ELVIS COVID-19, NCT04382131 Phase Not Applicable Not yet recruiting 1 3 Months 405 Aziz Sheikh, Emma Ward, Kenny Scott 2020-05-14
A two-phase clinical trial to examine the sensitivity and specificity of COVID-19 Ag Respi-Strip test to detect COVID-19 infection Coronavirus disease 19 infection COVID-19 Ag Respi-Strip test alone Universite Libre de Bruxelles Phase Not Applicable Status not specified 0 2020-05-14
COVID_REHAB: Rehabilitation for People With COVID-19 in ICU Coronavirus disease 19 infection, Respiratory distress syndrome Pulmonary and Motor Rehabilitation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Padova Azienda Ospedaliera Universitaria Integrata Di Verona, University Hospital Padova Italy 2020-05-10 2020-09-30 COVID_REHAB, NCT04381338, UPADOVA_1 Phase Not Applicable Not yet recruiting 2 4 Months 92 Alessandra Del Felice, MD, PhD, Katia Donadello, MD, PhD 2020-05-15
Blind, placebo-controlled, adaptive, randomized clinical trial of the efficacy and safety of the drug Allokin-alpha, lyophilisate for the preparation of a solution for subcutaneous administration (LLC Alloferon, Russian Federation) as part of complex therapy in patients with mild or moderate coronovirus infection (COVID-19) Coronavirus disease 19 infection Allokin-alpha alone Alloferon Russian Federation 2020-05-28 2024-12-31 ALO001 Phase 3 Clinical Status not specified 2 55 Months 206 2020-05-20
IMPACT: Using blood plasma to develop passive immunity to coronavirus in Ecuador Coronavirus disease 19 infection convalescent plasma alone, standard care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidad Tecnológica Equinoccial SalvarVidasEC Ecuador 2020-03-11 2020-12-31 IMPACT, ISRCTN85216856 Phase 2/Phase 3 Clinical Recruiting 1 9 Months 200 Dr Baldeon 2020-05-20
APLICOV-PC: Proof-of-Concept Study to Evaluate the Safety Profile of Plitidepsin in Patients With COVID-19 Coronavirus disease 19 infection, Viral pneumonia plitidepsin alone Elongation factor 1 alpha 2 modulator, VEGF-1 receptor modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) PharmaMar SA Apices Soluciones, S.L. Spain 2020-05-12 2020-11-30 2020-001993-31, APL-D-002-20, APLICOV-PC, NCT04382066 Phase 1 Clinical Recruiting 3 6 Months 27 Jesús Fortún, MD, José Barberán, MD, José Barberán, Md, Maria J Pontes, María A Fores, Vicente Estrada, MD 2020-05-18
SAM-COVID: Immunosupressive Treatment in COVID-19 Patients Coronavirus disease 19 infection, Macrophage activation syndrome immunoglobulin alone, steroid therapy alone, Variable regimens including anakinra , sarilumab , tocilizumab IL-6 receptor antagonist, Type I IL-1 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Spanish Network for Research in Infectious Diseases Fundación Pública Andaluza Para La Gestión De La Investigación En Salud De Sevilla Spain 2020-05-31 2020-05-31 FIS-INM-2020-03, NCT04382781, SAM-COVID Phase Not Applicable Recruiting 1 500 Jesús Rodriguez-Baño, MD, PhD, Sánchez-Barriga 2020-05-14
SAVIORII: Study Assessing Vagus Nerve Stimulation in COVID-19 Respiratory Symptoms Coronavirus disease 19 infection, Dyspnea, Respiratory distress syndrome gammaCore Sapphire alone, standard of care alone, vagus nerve stimulation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Allegheny-Singer Research Inst Electrocore Inc US 2020-05-08 2020-12-30 2020-132-AGH, NCT04382391, SAVIORII Phase Not Applicable Recruiting 0 7 Months 20 AHN Research Institute, Boyle Cheng, PhD, Clinical Trials Contact, Tariq Cheema, MD 2020-05-14
Combination of Recombinant Bacterial ACE2 Receptors-Like Enzyme of B38-CAP and Isotretinoin Could be Promising COVID-19 Infection and Lung Injury Preventing Drug Better Than Recombinant Human ACE2 Coronavirus disease 19 infection, Lung injury standard of care alone, isotretinoin plus rbACE2 Retinoic acid receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Kafrelsheikh University Egypt 2020-05-31 2020-09-30 COV-2019 TREATMENT THIS IS, NCT04382950 Phase 1 Clinical Not yet recruiting 2 4 Months 24 M.Sc. Mahmoud Elkazzaz, M.Sc.Biochemistry, M.Sc.Mahmoud Elkazzaz, M.Sc.Biochemistry, Mahmoud Ramadan mohamed Elkazzaz 2020-05-15
Novel Regimens in COVID-19 Treatment Coronavirus disease 19 infection Variable regimens including azithromycin , chloroquine (Alexoquine) , ivermectin , nitazoxanide Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tanta University Egypt 2020-05-08 2030-12-01 NCT04382846, TANTA COVID TREATMENT Phase 3 Clinical Not yet recruiting 1 126 Months 80 Sherief Abd-Elsalam, ass. prof., sherief Abd-Elsalam, Ass. Prof. 2020-05-14
COVIDNOCHE: COVIDNOCHE Trial (HFNO Versus CPAP Helmet) in COVID-19 Pneumonia Coronavirus disease 19 infection, Hypoxia, Respiratory failure, Viral pneumonia helmet continuous positive airway pressure therapy alone, high flow nasal oxygen therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Pennsylvania US 2020-05-31 2020-10-31 843124, COVIDNOCHE, NCT04381923 Phase Not Applicable Not yet recruiting 0 5 Months 200 Tim Gaulton, MD, MSc, Timothy Gaulton 2020-05-14
Co-infection Management in COVID-19 Critically Ill Coronavirus disease 19 infection, Viral pneumonia FilmArray Pneumonia test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Clinique Universitaires Saint-Luc, Universite Catholique de Louvain bioMerieux SA Belgium 2020-03-23 2020-04-24 2019/14MAR/124, NCT04382092 Phase Not Applicable Completed 1 1 Month 32 Alexia VERROKEN, MD, PhD 2020-05-13
Ivermectin Effect on SARS-CoV-2 Replication in Patients With COVID-19 Coronavirus disease 19 infection ivermectin alone, standard care alone Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Laboratorios Phoenix SAICF Universidad Nacional de Quilmes, Universidad Nacional de Salta Argentina 2020-05-11 2020-06-30 IVM-AR-1, NCT04381884 Phase 2 Clinical Recruiting 1 1 Month 45 Alejandro Krolewiecki, MD, Marcelo A Tinelli, MD, Mónica Lombardo, MD, Ricardo Valentini, MD 2020-05-20
Effect of Hydroxychloroquine on QTc Interval Coronavirus disease 19 infection hydroxychloroquine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Sanjay Gandhi Postgraduate Institute of Medical Sciences India 2020-05-18 CTRI/2020/05/025089 Phase Not Applicable Recruiting 1 50 Dr Mohan Gurjar 2020-05-13
A Cross-sectional and Cohort Study of COVID-19 Patients With Post-discharge Dysfunction Coronavirus disease 19 infection, Respiratory disease aerobic exercise alone, airway clearance training alone, breathing training alone, chest activity training alone, health education and energy saving techniques alone, local lung dilation techniques alone, rehabilitation instruction program alone, resistance training alone, self-rehabilitation exercises alone, systematic rehabilitation treatment program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Peking University Third Hospital China 2020-03-10 2020-12-31 M20200421, NCT04382534 Phase Not Applicable Recruiting 1 9 Months 300 Yuanmingfei Zhang, Dr. 2020-05-13
ZILU-COV: Zilucoplan in Improving Oxygenation and Short- and Long-term Outcome of COVID-19 Patients With Acute Hypoxic Respiratory Failure Acute lung injury, Coronavirus disease 19 infection, Hypoxia, Respiratory failure prophylactic antibiotic therapy alone, standard of care alone, zilucoplan alone Complement C5 factor inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitair Ziekenhuis Gent UCB SA Belgium 2020-05-31 2021-09-30 NCT04382755, ZILU-COV, ZILU-COV Phase 2 Clinical Not yet recruiting 9 16 Months 81 Anja Delporte, Bart Lambrecht, MDPhD, Bart N. Lambrecht, Karolien Vanhove, MD, Nikolaas De Neve, MD, Wim MD Terryn 2020-05-13
COLCHI-COVID: Randomized clinical trial to investigate the efficacy of early administration of colchicine in patients > 70 years of age and at high risk of pulmonary complications such as coronavirus-associated pneumonia Coronavirus disease 19 infection, Lung disease, Viral pneumonia colchicine alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundacion Instituto de Investigacion Marques de Valdecilla, IDIVAL Spain 2020-05-06 2020-001603-16, COLCHI-COVID, COLCHI-COVID Phase 3 Clinical Recruiting 1 1024 Maria del Mar Garcia, María del Mar García 2020-05-20
A phase III trial of BT-588 in Covid-19 patients Coronavirus disease 19 infection BT-588 alone Biotest AG Phase 3 Clinical Planned 0 2020-05-12
Study of GUDUCHI TABLET on healthy individuals to prevent covid 19 Coronavirus disease 19 infection guduchi alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Central Council for Research in Ayurvedic Sciences Ministry of Ayush India 2020-05-20 CTRI/2020/05/025088 Phase 1/Phase 2 Clinical Not yet recruiting 1 1200 Dr B vankatshwarlu, Dr K Anumol 2020-05-14
Covid-19 Infection and Pulmonary Distress Treatment With Zanubrutinib in Hospitalized Participants Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure supportive care treatment alone, zanubrutinib alone Btk tyrosine kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) BeiGene Co Ltd US 2020-05-31 2020-09-30 BGB-3111-219, NCT04382586 Phase 2 Clinical Not yet recruiting 0 4 Months 52 BeiGene, Todd Zimmerman, MD 2020-05-14
Convalescent Plasma versus Human Immunoglobulin to Treat COVID-19 Pneumonia Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure, Viral pneumonia convalescent plasma alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centenario Hospital Miguel Hidalgo Mexico 2020-05-06 2020-09-30 2020-A-10, NCT04381858 Phase 3 Clinical Recruiting 1 4 Months 500 Alejandro Castillo, MD, Jose Manuel Arreola Guerra, MD, MSc, PhD, Jose Manuel Arreola, MD,PhD, Lucila Martinez, MDPhD, Mario Gonzalez Gamez, MD, Victor Monroy, MD 2020-05-14
Observational, Cohort Study of Critically Ill Patients With Covid-19 in Sweden Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Vastmanland County Council (Landstinget) Sweden 2020-03-26 2021-05-31 NCT04382417, REGIONVASTMANLAND Phase Not Applicable Recruiting 2 14 Months 100 Bjorn Sjostrom, M.D., Björn Sjöstrom, M.D., Erland Ostberg, M.D., Ph.D. 2020-05-15
ImmunoCOVID: Coronavirus Infection in Primary or Secondary Immunosuppressed Children and Adults Coronavirus disease 19 infection Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Southampton NHS Foundation Trust Alder Hey Children's Hospital, Birmingham Children's Hospital NHS Foundation Trust, Bradford Royal Infirmary, Bristol Royal Hospital for Children, Cambridge University Hospitals NHS Foundation Trust, Cardiff and Vale University Health Board, East Lancashire Hospitals NHS Trust, Great North Children's Hospital, Great Ormond Street Hospital for Children NHS Foundation Trust, Imperial College Healthcare NHS trust, Leeds Children's Hospital, NHS Ayrshire And Arran, Norfolk and Norwich University Hospitals NHS Foundation Trust, Nottingham Children's Hospital, Oxford University Hospitals NHS Trust, Royal Alexandra Children's Hospital, Royal Hospital for Sick Children, Royal Manchester Children's Hospital, Royal Sussex County Hospital, Sheffield Children's NHS Foundation Trust, St George's University Hospitals NHS Foundation Trust, Swansea Bay University Health Board, The Royal Marsden NHS Trust, University College London Hospitals Charity, University Hospitals Coventry & Warwickshire NHS Trust UK 2020-03-22 2021-03-21 ImmunoCOVID, NCT04382508, RHM CHI1061 Phase Not Applicable Recruiting 1 12 Months 1500 Hans de Graaf, MD 2020-05-13
High-Dose Inhaled Nitric Oxide for COVID-19 (ICU Patients) Coronavirus disease 19 infection, Respiratory failure nitric oxide alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The University Health Network 2020-05-31 2020-12-31 20-5449, NCT04383002 Phase 1 Clinical Not yet recruiting 0 7 Months 20 Jennifer Lister 2020-05-13
SIDIACO-RETRO: Sitagliptin Treatment in Diabetic COVID-19 Positive Patients Coronavirus disease 19 infection, Non-insulin dependent diabetes, Respiratory failure, Viral pneumonia sitagliptin alone Dipeptidyl peptidase IV inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universita degli Studi di Milano Humanitas Hospital, Italy, IRCCS Policlinico San Matteo, Ospedale Papa Giovanni XXIII, Ospedale dell'Angelo, Universita Degli Studi di Pavia Italy 2020-05-14 2020-08-15 5/2020, NCT04382794, SIDIACO-RETRO Phase Not Applicable Recruiting 8 3 Months 200 Andrea Lania, MD, Angelo Guido Corsico, MD, Antonio Di Sabatino, MD, Carlo De Riva, MD, Elisabetta Lovati, MD, Marco Mirani, MD, Paolo Fiorina, MD, PhD, Roberto Trevisan, MD, Sebastiano Bruno Solerte, MD, Teresa Letizia, Dr. 2020-05-19
A Phase II, Controlled Clinical Study Designed to Evaluate the Effect of ArtemiC in Patients Diagnosed With COVID-19 Coronavirus disease 19 infection ArtemiC alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) MGC Pharmaceuticals d.o.o Israel 2020-05-08 2020-07-31 MGC-006, NCT04382040 Phase 2 Clinical Recruiting 2 2 Months 50 Ameer Elemy, Elias, Ilana Aloni, Jamil Muhsan, Nadia Lisovoder, Rubi Zomer 2020-05-16
HeSAcovid: Full versus prophylactic anticoagulation for the treatment of severe forms of Covid-19 Coronavirus disease 19 infection enoxaparin sodium alone, full heparinization alone, unfractionated heparin alone Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital of the Faculty of Medicine of Ribeirão Preto Conselho Nacional de Desenvolvimento Cientifico e Tecnologico - CNPq Brazil 2020-05-30 30958120.2.0000.5440, CEP: 4.000.967, HeSAcovid, RBR-949z6v, U1111-1251-4283 Phase 2 Clinical Recruiting 1 30 Carlos Henrique Miranda 2020-05-14
Evaluation of the efficacy and safety of pharmacological inhibition of bradykinin for the treatment of Covid-19 Coronavirus disease 19 infection CE-1145 alone, icatibant alone, standard care alone Bradykinin B2 receptor antagonist, Complement C1s subcomponent inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidade Estadual de Campina Fundacao de Amparo a Pesquisa do Estado Sao Paulo Brazil 2020-04-27 3.979.595, 30227920.9.0000.5404, RBR-5s2mqg, U1111-1250-1843 Phase 2/Phase 3 Clinical Recruiting 1 180 Lício Augusto Velloso 2020-05-14
Egyptian Initial Experience About 2019 Novel Corona Virus: Study of 48 Patients in Alexandria-Egypt Using Chest CT Chronic obstructive pulmonary disease, Coronavirus disease 19 infection, Immune disorder, Interstitial lung disease, Mycobacterium tuberculosis infection, Vascular disease CT scanning alone University of Alexandria Egypt 2020-02-01 2020-05-01 IRB (00012098), FWA (00018699), NCT04382469 Phase Not Applicable Completed 1 3 Months 48 Ahmed Samir, MD 2020-05-13
CórdobaTrail: Inhaled Ibuprofen to Treat COVID-19 Coronavirus disease 19 infection, Lung injury, Respiratory disease, Viral pneumonia ibuprofen alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Quimica Luar srl CONICET, Ceprocor - Centro De Excelencia En Prod Y Procesos De Córdoba Argentina 2020-05-01 2021-01-31 CórdobaTrail, DNL000004, NCT04382768 Phase 2 Clinical No longer recruiting 1 9 Months 40 Dante M Beltramo, PhD, Néstor H García 2020-05-20
Examination in COVID-19 pandemic: whether endoscopies really generate aerosol particles? Coronavirus disease 19 infection endoscopy alone, handheld particle counter model 3889 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Oita San-ai Medical Center Japan 2020-05-11 UMIN000040353 Phase Not Applicable Not yet recruiting 1 50 Ryota Sagami 2020-05-13
Safety and Efficacy of Hydroxychloroquine Associated With Azythromycin in SARS-Cov-2 Virus Coronavirus disease 19 infection hydroxychloroquine alone, proper COVID19 treatment alone, azithromycin plus hydroxychloroquine Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) EMS SA, Hospital do Coracao Brazil 2020-03-30 3.934.659, 30161220.0.1001.0060, RBR-9d8z6m Phase 3 Clinical Recruiting 1 630 Fernando Godinho Zampieri 2020-05-13
Study of Efficacy and Safety of DV-890 in Patients With COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia DFV-890 alone, standard of care (SOC) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Novartis AG 2020-05-15 2020-07-29 2020-001870-32, CDFV890D12201, NCT04382053 Phase 2 Clinical Not yet recruiting 0 2 Months 120 Novartis Pharmaceuticals, Novartis pharmaceuticals 2020-05-13
GA and COVID19: Potential Role of Gum Arabic as Immunomodulatory Agent Among COVID 19 Patients Coronavirus disease 19 infection Acacia senegal gum arabic intake alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Al-Neelain University University of Khartoum Sudan 2020-06-01 2020-09-01 GA and COVID19, GA& COVID19, NCT04381871 Phase 2/Phase 3 Clinical Not yet recruiting 2 3 Months 110 Dr Babiker, PhD, Lamis Kaddam, Moawia M Mukhtar, PhD, Mustafa KM Nimeiri, MD, Shahenaz Satti, MSc 2020-05-14
Factors influencing psychological response among healthcare workers during 2020 COVID-19 pandemic Coronavirus disease 19 infection, Psychiatric disorder Sultan Haji Ahmad Shah Hospital Malaysia 2020-05-18 2020-09-14 54947, NMRR-20-899-54947 Phase Not Applicable Status not specified 1 3 Months Dr Ahmad Ashraf Ilman bin Zulbahri 2020-05-13
Vertical Transmission, COVID-19, Clinical Characteristics, Outcomes, Mothers, Neonates Coronavirus disease 19 infection Hospital Sungai Buloh Malaysia 2020-05-11 2020-11-16 54821, NMRR-20-894-54821 Phase Not Applicable Status not specified 1 6 Months Dr Lee Yee Leng, Dr See Kwee Ching 2020-05-13
COVIDIMMUNOPSY: Immunity and Infections in the Psychiatric Population Coronavirus disease 19 infection, Psychiatric disorder serological COVID testing alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris INSERM 2020-05-10 2020-06-25 APHP200553, COVIDIMMUNOPSY, NCT04381845 Phase Not Applicable Not yet recruiting 0 1 Month 200 France GUYOT 2020-05-14
Nurses Mental Healh_COVID-19 Coronavirus disease 19 infection, Psychiatric disorder University of Malaya Malaysia 2020-05-15 2020-12-15 54719, NMRR-20-890-54719 Phase Not Applicable Not yet recruiting 1 7 Months Dr. Chui Ping Lei 2020-05-13
A phase I trial of COVI-SHIELD to potentially treat COVID-19 Coronavirus disease 19 infection COVI-SHIELD alone COVID19 Spike glycoprotein inhibitor Sorrento Therapeutics Inc Mount Sinai Health System 2020-09-30 Phase 1 Clinical Planned 0 2020-05-14
Hydroxychloroquine in SARS-CoV-2 (COVID-19) Pneumonia Trial Acute lung injury, Coronavirus disease 19 infection, Hypoxia, Respiratory distress syndrome, Viral pneumonia hydroxychloroquine alone, usual care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kootenai Health Washington State University US 2020-05-31 2022-06-01 18244, NCT04382625 Phase 4 Clinical Not yet recruiting 0 24 Months 120 Jeanette Berg, MD, PhD, John Roll, PhD, Sandra Albritton, MN,RN, Sean Cook, D.O., Shamela Barnett, Sterling McPherson, PhD 2020-05-13
The Impact of COVID-19 Pandemic on Cancer Care Cancer, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) El Zaitoun Specialized Hospital Egypt 2020-05-23 2020-07-31 CANCER CARE DURING COVID-19, NCT04382495 Phase Not Applicable Not yet recruiting 2 2 Months 200 Aalaa Abdou, Dr, Aalaa Abdou, MSc, Ahmed Abdelaziz, MD 2020-05-19
COVID-Impact: Impact of COVID-19 on Mental Health of Health Care Workers Coronavirus disease 19 infection, Psychiatric disorder Healthy volunteers accepted Universitair Ziekenhuis Gent Belgium 2020-04-17 2022-12-31 BC-07564, COVID-Impact, NCT04382196 Phase Not Applicable No longer recruiting 1 32 Months 497 Gilbert Lemmens 2020-05-14
Safety and Efficacy of NP-120 (Ifenprodil) for the Treatment of Confirmed COVID-19 Infected Hospitalized Patients Coronavirus disease 19 infection repurposed ifenprodil (oral, IPF/UC/IBD/crohn's disease/cough), Nash Pharmaceuticals alone, standard of care alone NMDA receptor epsilon 2 subunit inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Algernon Pharmaceuticals Novotech (Australia) Pty Ltd US, Australia, South Korea, Canada 2020-07-31 2022-02-28 AGN120-3, NCT04382924 Phase 2/Phase 3 Clinical Not yet recruiting 2 19 Months 462 Mark Williams, Ph.D., Nancy Stewart, Ph.D. 2020-05-19
Treatment of Covid-19 Associated Pneumonia With Allogenic Pooled Olfactory Mucosa-derived Mesenchymal Stem Cells Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia allogenic pooled olfactory mucosa-derived mesenchymal stem cells alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus Belarusian State Medical University Belarus 2020-05-11 2021-06-30 IBCE_MSC2(COVID), NCT04382547 Phase 1/Phase 2 Clinical Not yet recruiting 1 13 Months 40 Andrei Y Hancharou, Dr., Eduard A Dotsenko, Dr., prof., Natalia G Antonevich, Dr. 2020-05-14
A Study of Hydroxychloroquine versus Placebo to Prevent COVID-19 Infection in Patients Receiving Radiotherapy Breast tumor, Central nervous system tumor, Coronavirus disease 19 infection, Gastrointestinal tumor, Gynecological disorder, Head and neck tumor, Lung tumor, Prostate tumor, Skin cancer hydroxychloroquine alone, standard radiation therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Memorial Sloan-Kettering Cancer Center US 2020-05-07 2021-05-31 20-176, NCT04381988 Phase 2 Clinical Recruiting 0 12 Months 132 Nancy Lee, MD, Yao Yu, MD 2020-05-14
MAS-COVID: Study of Efficacy and Safety of MAS-825 in Patients With COVID-19 Coronavirus disease 19 infection, Viral pneumonia MAS-825 alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Novartis AG 2020-05-15 2020-11-05 CMAS825F12201, MAS-COVID, NCT04382651 Phase 2 Clinical Not yet recruiting 0 5 Months 120 Novartis Pharmaceuticals 2020-05-14
WARd-COVID: Non-invasive Ventilatory Support of Patients Affected by COVID-19 Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia continuous positive airway pressure therapy alone, high-flow nasal cannula therapy alone, non-invasive ventilation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Milano-Bicocca Italy 2020-03-26 2020-06-30 NCT04382235, WARD-COVID, WARd-COVID Phase Not Applicable No longer recruiting 34 3 Months 900 2020-05-14
An accelerated phase II study of BT-588 in COVID-19 patients Coronavirus disease 19 infection BT-588 alone Biotest AG Phase 2 Clinical Planned 0 2020-05-12
ATOMIC2: A Multicenter, Open-label, Two-arm, Randomized, Superiority Clinical Trial of Azithromycin Versus Usual Care In Ambulatory COVID-19 Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia standard usual care alone, azithromycin plus paracetamol Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Oxford Pfizer Inc 2020-05-13 2020-10-13 20/HRA/2105, 2020-001740-26, 282892, ATOMIC2, ATOMIC2, NCT04381962 Phase 3 Clinical Not yet recruiting 0 5 Months 800 Lucy Cureton, Paul Little, MD PhD, Timothy SC Hinks, MD PhD 2020-05-14
COUP19: COVID-19 associated neuropathy and myopathy in Germany Coronavirus disease 19 infection, Myopathy, Neuropathy neurological and neuropyhsiological examination alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bergmannsheil, Bochum University of Wurzburg, Universitätsklinikum Schleswig-Holstein Germany 2020-07-01 20-6925, COUP19, DRKS00021677 Phase Not Applicable Not yet recruiting 3 200 Elena Enax-Krumova, Mr. Prof. Dr. Ralf Baron, Ms. Dr. Christine Meyer-Frießem, Ms. Jun. Prof. Dr. Elena Enax-Krumova, Ms. PD Dr. Janne Gierthmühlen, Ms. Prof. Dr. Claudia Sommer, Ms. Prof. Dr. Nurcan Üçeyler, Universitätsklinikum Bergmannsheil gGmbH 2020-05-13
lnfluence of the COVID-19-pandemic on the treatment of ENT patients Coronavirus disease 19 infection Universitats-Augenklinik Freiburg Germany 2020-05-12 302/20, DRKS00021699, U1111-1251-7604 Phase Not Applicable Not yet recruiting 1 20000 Sarah Riemann 2020-05-14
Ventilation@MPI: Retrospective analysis of the relationship between invasive ventilation (considering COVID-19) and a Comprehensive Geriatric Assessment (CGA) Coronavirus disease 19 infection, Lung disease, Viral pneumonia Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital of Cologne Germany 2020-04-17 2020-04-30 20-1179, DRKS00021638, Ventilation@MPI Phase Not Applicable Completed 1 1276 Maria Cristina Polidori Nelles 2020-05-13
Norwegian SARS-CoV-2 Study - Virological, Clinical and Immunological Characterisation of COVID-19 Coronavirus disease 19 infection SARS-CoV-2 PCR alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Oslo University Hospital Haukeland University Hospital, Ostfold Hospital Trust, St Olavs Hospital, University Hospital of North Norway, University Hospital, Akershus, Vestre Viken HF Norway 2020-03-02 2023-12-31 20-04072, NCT04381819 Phase Not Applicable Recruiting 7 45 Months 1000 Anders B Kildal, PhD, Bjørn Blomberg, PhD, Christian Prebensen, PhD, Erik Solligård, PhD, Fredrik G Müller, Professor, Jan C Holter, PhD, Jonas Bergan, phd, Lars Heggelund, PhD, Susanne G Dudman, Ass.Professor, Susanne G Dudman, PhD, Susanne G Dudman, Professor 2020-05-13
Hydroxychloroquine in patients with mild COVID-19 illness with risk factors for severe disease Coronavirus disease 19 infection hydroxychloroquine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences India 2020-05-06 CTRI/2020/05/025022 Phase 2 Clinical Not yet recruiting 1 166 Dr Manish Soneja 2020-05-13
A Medical Records Based Study for Clinical Efficacy and Safety of 'clear lung detoxification soup' in the treatment of Novel Coronavirus Pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Qingfei Paidu Decoction alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences National Science and Technology Support Plan of the People's Republic of China China 2020-01-27 2020-07-27 ChiCTR2000032767 Phase Not Applicable No longer recruiting 13 6 Months 782 Shi Nannan, Wang Yanping 2020-05-13
Low-Dose Anti-inflammatory Radiotherapy for the Treatment of Pneumonia by COVID-19 Coronavirus disease 19 infection, Viral pneumonia low-dose radiotherapy (0.5 Gy) alone, Variable regimens including Dolquine , azithromycin , dexamethasone , heparin , lopinavir + ritonavir , methylprednisolone , oxygen , prednisone , tocilizumab (intravenous), Roche/Chugai HIV protease inhibitor, IL-6 receptor antagonist, IL-6 receptor modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Grupo de Investigación Clínica en Oncología Radioterapia Hospital Universitari Sant Joan de Reus, Hospital Universitario Madrid Sanchinarro, Hospital del Mar Spain 2020-05-08 2021-07-01 IPACOVID, NCT04380818 Phase 2 Clinical Recruiting 3 13 Months 106 ANGEL MONTERO, Md, PhD, Angel Montero, MD, PhD, MANEL ALGARA, MD, PhD, MERITXELL ARENAS, MD, PhD, Manel Algara, MD, PhD, Merirxell Arenas, MD, PhD 2020-05-12
Prevalence of Severe Bleeding in COVID-19 Patients Treated With Higher Than Recommended Thromboprophylaxis Doses Bleeding, Coronavirus disease 19 infection thromboprophylaxis therapy alone Foundation for the study of VTE diseases (FUENTE) Spain 2020-04-13 2025-06-13 BLEEDING042020, NCT04380779 Phase Not Applicable Recruiting 1 62 Months 5000 Manuel Monreal, Mayra Hawkins 2020-05-12
A Pilot Study Evaluating the Effect of NT-17, a Long Acting Interleukin-7, to Enhance Immune Clearance of SARS-CoV-2(COVID-19) Coronavirus disease 19 infection HyLeukin-7 alone, supportive care alone IL-7 receptor agonist, Interleukin-7 ligand Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Washington University School of Medicine, US US 2020-07-31 2021-02-28 04-20-20-CAMPIAN, NCT04380948 Phase 1 Clinical Not yet recruiting 0 7 Months 30 Erik R Dubberke, M.D., MSPH, Jian Campian, M.D., Ph.D., Jingqin (Rosy) Luo, Ph.D. 2020-05-13
A 6-week, controlled, two-arm randomized study of molecular iodine for protecting healthcare workers from COVID-19 exposure Coronavirus disease 19 infection CDC guidelines alone, ioCleanse Hand Cleanser alone, ioMist Nasal Spray alone, ioRinse Oral Rinse alone Iotech International Llc US Phase Not Applicable Recruiting 0 300 Dr. Hillel Ephros 2020-05-11
Efficacy and Safety of Polyoxidonium in Hospitalized Patients With Coronavirus Disease COVID-19 Coronavirus disease 19 infection Polyoxidonium alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) NPO Petrovax Pharm LLC Russian Federation 2020-04-29 2021-04-30 NCT04381377, PО-COV-III-20 Phase 2/Phase 3 Clinical Recruiting 12 12 Months 394 A. A. Grebenyuk, A. A. Ploskireva, A. S. Pankov, D. A. Lioznov, D. N. Protsenko, E. G. Tikhomolova, I. G. Gordeev, I. G. Sitnikov, Jean-Francois Rossi, Professor, L. V. Kolobukhina, M. V. Smirnov, Nikolay Dodonov, S. K. Zyryanov, V. V. Kulabukhov 2020-05-12
HALT COVID-19: Inhalation of Ciclesonide for Patients With COVID-19: A Randomized, Open Treatment Study Coronavirus disease 19 infection ciclesonide (metered dose inhaler), Teijin/Covis/AstraZeneca alone Glucocorticoid receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Capio Saint Göran's Hospital Danderyd Hospital, Karolinska University Hospital, Vasteras Central Hospital Sweden 2020-05-15 2020-12-31 2020-02183, HALT COVID-19, NCT04381364 Phase 2 Clinical Not yet recruiting 4 7 Months 446 Anders Krifors, MD, Daniel Brodin, MD, Daniel P Andersson, MD, PhD, Magnus Bager, MD, Ola Blennow, MD, PhD 2020-05-13
Emergency Ventilator Splitting Between Two or More Patients (COVID-19) Coronavirus disease 19 infection emergency ventilator splitter alone, oxygen therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Stanford University US 2020-05-31 2020-06-30 55989, NCT04381013 Phase Not Applicable Not yet recruiting 0 1 Month 4 Joseph Woo, MD 2020-05-13
STATCO19: Atorvastatin in COVID-19 Coronavirus disease 19 infection atorvastatin alone HMG CoA reductase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mount Auburn Hospital 2020-05-08 2022-05-08 MOUNTAUBURN, NCT04380402, STATCO19 Phase 2 Clinical Not yet recruiting 0 24 Months 300 2020-05-12
Asymptomatic novel coronavirus pneumonia (COVID-19) patients Have Longer Treatment Cycle Than Mild and Moderate Patients: a medical records based study Coronavirus disease 19 infection, Viral pneumonia Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The Science and Technology Department of Guizhou Province China 2020-01-29 2020-03-31 ChiCTR2000032770 Phase 0 Clinical Completed 1 2 Months 52 Wei Zhang 2020-05-12
Co-Stars: COVID-19 Staff Testing of Antibody Responses Study Coronavirus disease 19 infection serological testing alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Great Ormond Street Hospital for Children NHS Foundation Trust UK 2020-04-27 2026-07-27 20CB17, Co-Stars, NCT04380896 Phase Not Applicable Recruiting 1 75 Months 1000 Louis Grandjean, Dr, Vanshree Patel, Dr 2020-05-18
Correlation between novel coronavirus pneumonia (COVID-19) and mental health of breast cancer patients: a cross-sectional study in Hunan Province Coronavirus disease 19 infection, Psychiatric disorder Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Xiangya Hospital Of Central South University Hunan Provincial Natural Science Foundation China 2020-01-01 ChiCTR2000032768 Phase Not Applicable Completed 1 309 Ling Wang 2020-05-11
Clinical efficacy of Nafamostat for COVID-19 pneumonia Coronavirus disease 19 infection, SARS coronavirus infection Nafamostat alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gyeongsang National University Hospital Ministry of Science and ICT South Korea 2020-05-25 GNUH-2020-04-012, KCT0005003 Phase 2 Clinical Not yet recruiting 7 84 In-Gyu Bae 2020-05-12
PanCOVID: Covid-19 Pandemic and Pancreatic Surgery in Italy Coronavirus disease 19 infection, Pancreas tumor pancreatic surgery alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fondazione Policlinico Universitario Agostino Gemelli IRCCS Italy 2019-01-01 2020-06-30 FPGEMELLIIRCCS, NCT04380766, PanCOVID Phase Not Applicable Recruiting 1 18 Months 700 Sergio Alfieri, Sergio Alfieri, MD 2020-05-13
Effectiveness and Safety of Convalescent Plasma Therapy on COVID-19 Patients With Acute Respiratory Distress Syndrome Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia convalescent plasma alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Indonesia Dr Cipto Mangunkusumo General Hospital, Faculty of Medicine, University of Indonesia Indonesia 2020-05-11 2020-08-31 CONVALESCENT PLASMA RSCM-FKUI, NCT04380935 Phase 2/Phase 3 Clinical Not yet recruiting 3 3 Months 60 Andri MT Lubis, MD, PhD, Andri Maruli Tua Lubis, Cosphiadi Irawan, MD, PhD, Elida Marpaung, MD, MBiomed, Lugyanti Sukrisman, MD, PhD, Robert Sinto, MD, Siti Rizny F Saldi, Pharm, MSc, William Djauhari, MD 2020-05-12
Evaluation of BCG as potential therapy for COVID-19 Coronavirus disease 19 infection BCG alone Young Adults (18-44 yrs) Haffkine Biopharmaceutical Corporation Ltd., Medical Education and Drugs Department India 2020-05-06 BIO/CT/20/000049, CTRI/2020/05/025013 Phase 2 Clinical Not yet recruiting 1 60 Dr Rajesh Deshmukh, Dr Sanjay Mukherjee, Dr Sonali Salvi, Dr Usha Padmanabhan 2020-05-11
Evaluation of the effect of jujube product on Covid-19 patients Coronavirus disease 19 infection jujube alone, routine protocol alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Semnan University of Medical Sciences Iran 2020-05-09 IR.SEMUMS.REC.1399.032, IRCT20171213037866N2 Phase 3 Clinical Recruiting 1 68 Ali Gohari, Nasim Behnoud, Parviz Kokhaie 2020-05-12
The effectiveness of educational-treatment package based on psychological flexibility in burnout, quality of working life, work-family conflict and mental health Coronavirus disease 19 infection training package alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Isfahan University of medical Sciences Iran 2020-05-04 IR.MUI.MED.REC.1399.026, IRCT20200413047052N1 Phase Not Applicable Recruiting 1 60 Amrolla Ebrahimi, Amrullah Ebrahimi, Sayed Mohammad Hosein Mosavi 2020-05-12
Study for the Use of the IL-6 Inhibitor Clazakizumab in Patients With Life-threatening COVID-19 Infection Coronavirus disease 19 infection, Lung failure, Respiratory distress syndrome clazakizumab alone IL-6 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Columbia University NYU Langone Health, Vitaeris Inc US 2020-05-31 2020-08-01 AAAT0142, NCT04381052 Phase 2/Phase 3 Clinical Not yet recruiting 0 2 Months 30 David J Cohen, MD, David J. Cohen, MD, Melanie Foley 2020-05-13
A phase III study of EDP-1815 for the treatment of COVID-19 infection Coronavirus disease 19 infection EDP-1815 alone Evelo Biosciences Inc Phase 3 Clinical Planned 0 2020-05-11
Describing Chinese Herbal Medicine Telehealth Care for Symptoms Related to Infectious Diseases Such as COVID-19 Coronavirus disease 19 infection Chinese herbal medicine (Spring Wind Herb Company) alone, telehealth care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Center for Integrated Care University of California San Francisco, University of Utah US 2020-04-11 2025-04-11 01-04-20, NCT04380870 Phase Not Applicable Recruiting 0 60 Months 500 Katherine Taromina, Katherine Taromina, DACM, Lee Hullender Rubin, DAOM, Lee Hullender Rubin, DOAM, Lisa A Conboy, ScD, Lisa Taylor-Swanson, PhD 2020-05-13
A phase II, double-blind, placebo-controlled study to assess the safety and efficacy of EDP-1815 for the treatment of hospitalized patients with newly diagnosed COVID-19 Coronavirus disease 19 infection EDP-1815 alone, standard of care alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Evelo Biosciences Inc, Robert Wood Johnson University Hospital, Rutgers University US 2020-12-31 EDP1815-205 Phase 2 Clinical Planned 0 60 Reynold A. Panettieri, Jr., M.D 2020-05-14
MiRCOVID: Noncoding RNAs in COVID-19 and COVID-19 Related Kidney Dysfunction Coronavirus disease 19 infection, Renal injury Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Heinrich Heine Universitat Dusseldorf Germany 2020-04-16 2021-07-31 1, MiRCOVID, NCT04381351 Phase Not Applicable Recruiting 1 15 Months 50 Dr. Timo Brandenburger, Timo Brandenburger, MD 2020-05-14
Predi-COVID: Luxembourg Cohort of Positive Patients for COVID-19: a Stratification Study to Predict Patient Prognosis Coronavirus disease 19 infection biological sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Luxembourg Institute of Health Centre Hospitalier de Luxembourg, Hopitaux Robert Schuman (Luxembourg), Laboratoire National de santé, Universite of Luxembourg Luxembourg 2020-05-04 2021-12-31 NCT04380987, PREDI-COVID, Predi-COVID Phase Not Applicable Recruiting 1 19 Months 200 Aurelie Fischer, MS, Laetitia Huiart, MD, PhD, Manon Gantenbein, PhD 2020-05-14
Changes in the Consumption of Psychoactive Substances During Containment Linked to COVID-19 Coronavirus disease 19 infection psychoactive substances alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Montpellier France 2020-05-01 2020-08-01 NCT04380714, RECHMPL20-0273 Phase Not Applicable Recruiting 1 3 Months 700 Aurélie Mieuset, MD, Aurélie Mieuset, PhD 2020-05-14
Oral Health and Psychosocial Factors During the COVID-19 Pandemic Coronavirus disease 19 infection, Periodontitis, Psychiatric disorder Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Heidelberg Germany 2020-05-08 2020-07-31 NCT04381273, S-303/2020 Phase Not Applicable Recruiting 1 2 Months 1000 Antonio Ciardo, Dr. 2020-05-12
Study to Evaluate the Safety and Efficacy of Prolastin in Hospitalized Patients with Coronavirus Disease (COVID-19) Coronavirus disease 19 infection Prolastin alone, Standard Medical Treatment alone Alpha 1 proteinase inhibitor, Serine protease inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Grifols SA Spain 2020-05-08 2020-001953-36, GC2005 Phase 2 Clinical Recruiting 1 100 Department of Clinical Trials 2020-05-13
Efficacy and safety study of IVIG in hospitalized subjects with COVID-19 Coronavirus disease 19 infection Flebogamma 10% DIF alone, Flebogamma DIF 5% alone, Standard Medical Treatment (SMT) alone Beta amyloid modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Grifols SA Spain 2020-05-08 2020-001696-32, GC2004 Phase 2 Clinical Recruiting 1 100 Department of Clinical Trials 2020-05-20
Study of the efficacy of ivermectin in the treatment and prevention of COVID-19 Coronavirus disease 19 infection ivermectin alone Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundació Recerca Mútua Terrassa (FMT) Spain 2020-05-06 2020-001994-66, ECIT-PRO19 Phase 3 Clinical Recruiting 1 266 Clinical trial 2020-05-13
Tableted COVID-19 Therapeutic Vaccine (COVID-19) Coronavirus disease 19 infection V-SARS alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Immunitor LLC Immunitor Inc Canada 2020-06-15 2021-06-15 IMM24, NCT04380532 Phase 1/Phase 2 Clinical Recruiting 1 12 Months 20 Aldar Bourinbaiar, MD/PhD, Allen Bain, PhD 2020-05-12
GLUCOCOVID: Use of corticosteroids in patients with sars-cov2 coronavirus infection Coronavirus disease 19 infection Urbason alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundacion Instituto de Investigacion Marques de Valdecilla, IDIVAL Spain 2020-05-07 2020-001934-37, GLUCOCOVID, GLUCOCOVID Phase 4 Clinical Recruiting 1 200 Mar García Sáiz 2020-05-13
COVIDADOMEVA: Risk Factors Worsening COVID-19 for Out-patient With Home Monitoring Coronavirus disease 19 infection University Hospital, Grenoble France 2020-05-20 2020-12-30 2020-A01040-39, 38RC20.135, COVIDADOMEVA, NCT04380662 Phase Not Applicable Not yet recruiting 1 7 Months 800 Guillaume DEBATY, MD-PhD, Olivier EPAULARD, MD-PhD, Sandra DAVID-TCHOUDA, MD, Sandrine MASSICOT, Master 2020-05-20
SAINT: Sars-CoV-2/COVID-19 Ivermectin Navarra-ISGlobal Trial Coronavirus disease 19 infection ivermectin alone Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Clinica Universidad de Navarra, University of Navarra Barcelona Institute for Global Health Spain 2020-05-14 2020-08-30 2020-001474-29, NCT04390022, SAINT, SAINT Phase 2 Clinical Not yet recruiting 1 3 Months 24 Carlos Chaccour, MD, Carlos J Chaccour, MD PhD, Irene Canales, UCEC 2020-05-20
ACHIEVE: Clarithromycin in COVID-19 Coronavirus disease 19 infection clarithromycin alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hellenic Institute for the Study of Sepsis Greece 2020-05-07 2020-001882-36, ACHIEVE, ACHIEVE Phase 2 Clinical No longer recruiting 1 90 President of the Board 2020-05-13
A trial to compare standard of care (SOC) alone with SOC plus hydroxychloroquine or SOC with a combination of hydroxycholorquine and azithromysin in the treatment of coronovirus Coronavirus disease 19 infection azithromycin alone, hydroxychloroquine alone, standard of care alone, azithromycin plus hydroxychloroquine Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University College Dublin Ireland 2020-05-05 2020-001265-36, UCDCRC/20/01 Phase 4 Clinical No longer recruiting 1 267 QRAM 2020-05-13
COVID-OLD: Direct and Indirect Impact of COVID-19 In Older Populations Coronavirus disease 19 infection Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Grenoble France 2020-04-09 2021-10-09 2020-A00846-33, 38RC20.118, COVID-OLD, NCT04381312 Phase Not Applicable Recruiting 1 18 Months 1000 Gaetan GAVAZZI, Pr, Gaëtan Gavazzi, PhD Professor, Saber Touati, ARC 2020-05-12
A randomized, double-blind, placebo-controlled clinical trial to assess whether hydroxychloroquine and azithromycin reduce hospitalization and/or death in individuals suffering from COVID-19 Coronavirus disease 19 infection azithromycin alone, hydroxychloroquine alone National Institutes of Health US Phase Not Applicable Recruiting 0 2000 Eric Daar 2020-05-12
A clinical trial of CERC-002 for potential treatment of Acute Respiratory Distress Syndrome (“ARDS”) and Acute Lung Injury (“ALI”) in hospitalized COVID-19 patients Acute lung injury, Coronavirus disease 19 infection, Respiratory distress syndrome CERC-002 alone Tumor necrosis factor 14 ligand inhibitor Cerecor Inc Phase Not Applicable Recruiting 0 2020-05-11
COVID-19 HOPE Study: A clinical study to assess AT-H201 in the treatment of subjects with COVID-19 infection Coronavirus disease 19 infection AT-H201 alone Atossa Genetics Inc US COVID-19 HOPE Study Phase Not Applicable Not yet recruiting 0 2020-05-11
A Study to Evaluate the Efficacy and Safety of Sirukumab in Confirmed Severe or Critical Confirmed Coronavirus Disease (COVID)-19 Coronavirus disease 19 infection sirukumab alone, standard of care (SOC) alone IL-6 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Janssen Pharmaceutica NV US 2020-04-24 2020-09-16 CNTO136COV2001, CR108820, NCT04380961 Phase 2 Clinical Recruiting 0 4 Months 270 Study Contact 2020-05-14
SCREENING: Prevalence of DVT or PE in Patients Infected With COVID-19 Admitted to Hospital Coronavirus disease 19 infection, Deep vein thrombosis, Lung embolism ultrasonography alone Foundation for the study of VTE diseases (FUENTE) Spain 2020-04-13 2025-06-30 NCT04380792, SCREENING, SCREENING042020 Phase Not Applicable Recruiting 1 62 Months 5000 Manuel Monreal, Mayra Hawkins 2020-05-12
MEND: An open-label, randomized controlled clinical trial to investigate early efficacy of Cymerus mesenchymal stem cells (MSCs) in adults admitted to intensive care with COVID-19 and respiratory distress Coronavirus disease 19 infection, Respiratory distress syndrome mesenchymoangioblast-derived mesenchymal stem cell therapy (Cymerus, critical limb ischemia/graft versus host disease/asthma/diabetic foot ulcer), Cynata/FUJIFILM alone, standard of care alone Cynata Therapeutics Ltd Cerebral Palsy Alliance Research Foundation Australia MEND Phase Not Applicable Not yet recruiting 1 24 2020-05-13
Spread COVID 19 ED: Sorting the wheat form the chaff – COVID-19 in the Emergency department Coronavirus disease 19 infection SARSCov2-swab test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitatsklinikum Essen Germany 2020-05-07 20-9310-BO, DRKS00021675, Spread COVID 19 ED Phase Not Applicable Recruiting 1 383 Joachim Risse 2020-05-18
Clinical trial on the treatment of novel coronavirus pneumonia (COVID-19) patients suspected with gut microbiota dysbiosis with washed microbiota transplantation Coronavirus disease 19 infection Routine treatment alone, Washed microbiota transplantation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Guangzhou 8th People's Hospital China 2020-05-08 2021-06-08 2020KZDZX1132, ChiCTR2000032737 Phase 0 Clinical Not yet recruiting 2 13 Months 60 Li-Hao Wu, Zhi-Ning Ye 2020-05-12
Clinical trial evaluating two ventilator settings in Corona virus related severe lung diseases ( known as ARDS) Coronavirus disease 19 infection, Respiratory distress syndrome Lowest driving pressure guided PEEP alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences India 2020-05-16 CTRI/2020/05/025071 Phase 3 Clinical Not yet recruiting 1 40 Dr Ajisha Aravindan 2020-05-12
TRANSPULMONARY-COVID19: Transpulmonary Driving Pressure in ARDS COVID-19 Patients Coronavirus disease 19 infection, Respiratory distress syndrome Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Montpellier France 2019-04-01 2021-12-31 NCT04381286, RECHMPL20_0194, TRANSPULMONARY-COVID19 Phase Not Applicable Recruiting 1 33 Months 40 Ramin SEVERIN, MD, Ramin Séverin, MD 2020-05-13
MICOV: Low-doses Melphalan Inhalation in Patients With COVID-19 (Coronavirus Disease 2019) Pneumonia Bacterial pneumonia, Coronavirus disease 19 infection, Viral pneumonia Alkeran alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Federal State Budgetary Institution, Pulmonology Scientific Research Institute Medsi Clinic #1, Moscow, Moscow State Medical and Dental University Russian Federation 2020-04-30 2020-10-30 MICOV, NCT04380376, PSRI05-20 Phase 2 Clinical Recruiting 2 6 Months 60 Anna Rvacheva, PhD, Evgeny Sinitsyn, Evgeny Sinitsyn, MD, Kiril A Zykov, Prof, Kirill A Zykov, Prof, Kirill Zykov, MD, Kirill Zykov, Prof 2020-05-13
Had COVID-19 Spread in Nagasaki Prefecture before the first confirmed case? Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Nagasaki University Japan 2020-06-01 UMIN000040278 Phase Not Applicable Not yet recruiting 1 182 Katsunori Yanagihara, Norihito Kaku 2020-05-12
Almitrine and COVID-19 Related Hypoxemia Coronavirus disease 19 infection, Hypoxia Mostcare (Vygon) alone, Vectarion (Servier Laboratory) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Hospital, Nancy, France France 2020-03-20 2020-04-25 COVID-19_CHRU NANCY_2020PI080, NCT04380727 Phase Not Applicable Completed 1 1 Month 17 Marie Reine LOSSER, MD, PhD 2020-05-13
Immunological efficacy of Qing Fei Pai Du Tang for COVID-19 Coronavirus disease 19 infection Qing Fei Pai Du Tang alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Tokyo Takanawa Hospital Japan 2020-05-09 UMIN000040341 Phase 2 Clinical No longer recruiting 1 15 Tomoka Ebisui, Tsutomu Nakamura 2020-05-15
Study on risk perception and behavioral change related to COVID-19 Coronavirus disease 19 infection educational counseling alone, training alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Tokyo Ministry of Education, Culture, Sports, Science and Technology of Japan Japan 2020-05-12 UMIN000040286 Phase Not Applicable Not yet recruiting 1 1980 Tsuyoshi Okuhara 2020-05-11
Impacts of COVID-19 on frailty in community-dwelling older adults; a cross-sectional study Coronavirus disease 19 infection Aged Adults (65-79 yrs), Elderly Adults (80 and over) Takasaki University of Health and Welfare Japan 2020-05-08 UMIN000040335 Phase Not Applicable Not yet recruiting 1 346 Tomoyuki Shinohara 2020-05-18
CALAVI US: Acalabrutinib Study With Best Supportive Care Versus Best Supportive Care in Subjects Hospitalized With COVID-19 Coronavirus disease 19 infection, Viral pneumonia acalabrutinib alone, best supportive care alone Btk tyrosine kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) AstraZeneca Pharmaceuticals LP Acerta Pharma BV US 2020-05-12 2020-09-30 CALAVI US, D822FC00003, NCT04380688 Phase 2 Clinical Not yet recruiting 0 4 Months 60 AstraZeneca Clinical Study Information Center 2020-05-12
KomCo: Communication in times of the corona virus pandemic (COVID-19) Coronavirus disease 19 infection Universitätsmedizin Rostock Germany 2020-04-02 A 2020-0068, DRKS00021676, KomCo Phase Not Applicable Recruiting 1 200 Christian Junghanß 2020-05-13
An international clinical trial of oral macrophage activating factor in the prevention of the COVID-19 associated cytokine storm Coronavirus disease 19 infection macrophage activating factor alone Saisei Pharma Co Ltd Phase Not Applicable Planned 0 2020-05-11
A double-blind clinical study to evaluate the efficacy of the Manremyc food supplement for those health professionals who are most exposed to the risk of contracting COVID-19 Coronavirus disease 19 infection Manremyc alone Reig Jofre Group IDIAP jordi gol, Institut Germans Trias I Pujol (Igtp) Spain 2020-05-31 Phase Not Applicable Recruiting 1 300 Dr. Pere-Joan Cardona 2020-05-11
Effect of propolis in COVID-19 Coronavirus disease 19 infection propolis alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Abadan University of Medical Sciences Iran 2020-05-21 IR.ABADANUMS.REC.1399.031, IRCT20200326046868N1 Phase 3 Clinical Not yet recruiting 1 88 Reza Malihi, Sara Mobarak 2020-05-12
The effect of herbal syrup on patients with Corona Coronavirus disease 19 infection herbal thyme syrup intake alone, azithromycin plus lopinavir + ritonavir HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Mazandaran University of Medical Sciences Iran 2020-04-04 IR.MAZUMS.REC.1398.1456, IRCT20131129015584N2 Phase 3 Clinical Recruiting 1 152 Assie Jokar, Dr Assie Jokar, Dr Majid Saidi 2020-05-12
The Effect of Convalescent Plasma Therapy on Patients with 19-COVID Coronavirus disease 19 infection convalescent plasma therapy alone, routine treatment alone Ardabil University of Medical Sciences Iran 2020-05-12 IR.ARUMS.REC.1399.052, IRCT20150808023559N21 Phase 1/Phase 2 Clinical Recruiting 1 60 Effat Irani Jam, Shahab Bohlooli, Somaieh Matin 2020-05-12
Effect of interferon-beta1 (Zifron) on clinical improvement and prognosis of COVID-19 in Tabriz Imam-Reza hospital Coronavirus disease 19 infection, Respiratory failure Variable regimens including hydroxychloroquine , interferon-beta1, Zifron Zist Darou Danesh , lopinavir + ritonavir HIV protease inhibitor Zist Daru Danesh Company Iran 2020-04-29 IR.TBZMED.REC.1399.019, IRCT20200406046968N3 Phase 2 Clinical Recruiting 1 60 Hooshmand Ilka, Mikaeili Haleh 2020-05-12
RAVEN: Ruxolitinib therapy to Avoid Ventilation and improve outcome for deteriorating COVID-19 patients Coronavirus disease 19 infection ruxolitinib (oral, myeloproliferative disorders), Incyte/Novartis alone Jak1 tyrosine kinase inhibitor, Jak2 tyrosine kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Guy's & St Thomas' Hospital NHS Trust Novartis Pharmaceuticals UK Ltd UK 2020-05-06 2020-001777-71, RAVEN, RAVEN Phase 4 Clinical No longer recruiting 1 59 Donal McLornan 2020-05-12
A phase II trial of PPP-003 in covid-19 infected patients Coronavirus disease 19 infection PPP-003 (intravenous), Tetra Bio-Pharma alone Cannabinoid CB2 receptor agonist Tetra Bio-Pharma Inc Onegevity Health LLC Phase 2 Clinical Planned 0 100 2020-05-12
Fact-finding survey on subclinical infection of SARS-CoV-2 in Kanagawa Prefecture Coronavirus disease 19 infection Test for COVID-19 alone Kanagawa Physicians Association Japan 2020-05-20 UMIN000040333 Phase Not Applicable Not yet recruiting 1 1500 Ikuro Matsuba 2020-05-15
A clinical trial of DARPin for the potential treatment of COVID-19 caused by SARS-CoV-2 Coronavirus disease 19 infection DARPin (COVID-19), Molecular Partners alone Angiotensin converting enzyme 2 inhibitor Molecular Partners AG 2020-12-31 Phase Not Applicable Planned 0 2020-05-11
Psychological effects of social isolation in the pandemic coronavirus Coronavirus disease 19 infection social isolation alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidade Federal do Para Colombia, Chile, Brazil, Spain, France, US, Portugal, UK, Canada 2020-04-07 2020-05-30 3,960,596, 30365720.8.0000.0008, RBR-9pgwfc, U1111-1250-1962 Phase Not Applicable Recruiting 8 1 Month 2300 Janari Silva Pedroso 2020-05-13
Investigating a Vaccine Against COVID-19 (COV002): Investigating a vaccine against COVID-19 Coronavirus disease 19 infection ChAdOx1 nCoV-19 alone, Nimenrix alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Oxford Coalition for Epidemic Preparedness Innovations, United Kingdom Research & Innovation UK 2020-03-02 2021-06-30 2020-001228-32, COV002, CPMS 45551, IRAS 281904, ISRCTN90906759, Investigating a Vaccine Against COVID-19 (COV002) Phase 2/Phase 3 Clinical Not yet recruiting 7 15 Months 5260 Mrs Plested 2020-05-16
An Expanded Access program of use of Convalescent Plasma for Severe COVID-19 Coronavirus disease 19 infection convalescent plasma alone OneBlood, University of Miami Health System Phase Not Applicable Status not specified 0 Shweta Anjan 2020-05-08
A phase I clinical trial of live attenuated SARS-CoV-2 virus vaccine for the prevention of SARS-CoV-2 COVID-19 infection Coronavirus disease 19 infection SARS-CoV-2 vaccine (recombinant measles virus vector, COVID-19), German Center for Infection Research alone COVID19 Spike glycoprotein modulator, COVID19 nucleoprotein modulator German Center for Infection Research (DZIF) Phase 1 Clinical Planned 0 2020-05-11
Study for the application of novel coronavirus pneumonia (COVID-19) intestinal tract toxicity in diagnosis and its prognostic effect Coronavirus disease 19 infection, Viral pneumonia probiotic plus rifaximin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Union Hospital Tongji Medical School Huazhong University Of Science & Technology China 2020-05-04 2021-12-31 ChiCTR2000032686 Phase Not Applicable Not yet recruiting 1 19 Months 390 Xiaohua Hou, Yu Jin 2020-05-11
Follow-up study of pregnancy outcomes of novel coronavirus pneumonia (COVID-19) complicated in the first and second trimester Coronavirus disease 19 infection Female, Young Adults (18-44 yrs) Union Hospital Tongji Medical School Huazhong University Of Science & Technology China 2020-04-01 2020-12-31 ChiCTR2000032666 Phase Not Applicable Recruiting 1 9 Months 6 Zhao Yin 2020-05-11
A phase I clinical trial to assess the tolerability and immune response of recombinant MVA vector vaccine fo the prevention of SARS-CoV-2 COVID-19 infection Coronavirus disease 19 infection recombinant MVA vector vaccine (COVID-19), German Center for Infection Research alone COVID19 Spike glycoprotein modulator German Center for Infection Research (DZIF) Phase 1 Clinical Planned 0 2020-05-08
A clinical trial of SARS-CoV-2 therapy for the prevention/treatment of COVID-19 infection Coronavirus disease 19 infection SARS-CoV-2 therapy (COVID-19), Shionogi/Hokkaido University Research Center alone Hokkaido University, Shionogi & Co Ltd Phase Not Applicable Planned 0 2020-05-08
Study for efficacy and safety of Jie-Xing-Jun-Zi granules in the Treatment of convalescent patients of novel coronavious pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Jiexingjunzi granules alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) The Third affiliated Hospital of Beijing Traditional Chinese Medicine University China 2020-05-01 2020-12-31 ChiCTR2000032313, ChiMCTR2000003243 Phase 0 Clinical Not yet recruiting 3 8 Months 60 Hongsheng Cui, Xinxin Qin 2020-05-11
A medical records based study for optimization and evaluation of the comprehensive diagnosis and treatment of novel coronavirus pneumonia (COVID-19) and the assessment of risk factors for severe pneumonia Coronavirus disease 19 infection, Viral pneumonia The First Affiliated Hospital of Nanchang University China 2020-01-31 2020-07-31 ChiCTR2000030095 Phase 0 Clinical Recruiting 1 6 Months 94 Anjun Chen, Wei Zhang 2020-05-11
Study for Screening of Chinese Patent Drugs in the Rehabilitation Treatment of Novel Coronavirus Pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Pien Tze Huang capsule plus thymosin enteric capsule Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hubei province hospital of Traditional Chinese Medicine Ministry of Science and Technology of the People´s Republic of China China 2020-04-01 2021-03-31 ChiCTR2000032635, ChiMCTR2000003279 Phase 0 Clinical Not yet recruiting 1 12 Months 60 He Shaobin, Zhuo Yana 2020-05-11
Moxibustion Plus Cupping in Convalescent Patients With COVID-19 Coronavirus disease 19 infection Moxibustion plus Cupping alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Guang'Anmen Hospital China Academy of Chinese Medical Sciences Ezhou Hospital of traditional Chinese Medicine in Hubei Province, Huangshi Hospital of Traditional Chinese Medicine, Hubei Hospital of Integrated Traditional Chinese and Western Medicine Zhongshan Branch, Hubei province hospital of Traditional Chinese Medicine, Shenzhen Baoan Hospital of Tradition Chinese Medicine, The Affiliated Hospital of JiangXi University of TCM, China, The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine, Wuhan Hospital of Traditional Chinese Medicine, Wuhan third Hospital China 2020-05-31 2021-12-31 2020YFC0845000, NCT04374084 Phase Not Applicable Not yet recruiting 1 19 Months 60 Jiani Wu, Xiaopin Wang, Zhongyu Zhou 2020-05-12
SurgiCovid: Surgical Activity During the Covid-19 Pandemic: Results for 112 Patients in a French Tertiary Care Center Coronavirus disease 19 infection Computed tomography chest alone, Reverse transcription polymerase chain reaction test alone, Screening test for covid alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospices Civils De Lyon France 2020-03-19 2020-04-25 CRC_GHN_2020_001, NCT04379232, SurgiCovid Phase Not Applicable Completed 1 1 Month 112 2020-05-11
FUTURE-T: Clinical Effect of Dialyzable Leukocyte Extract in Suspected or Confirmed Cases of COVID-19 Coronavirus disease 19 infection Dialyzable Leukocyte Extract alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto Politecnico Nacional Mexico 2020-05-31 2020-12-31 FUTURE-T, IC-20-001, NCT04379479, SH-001-2020 Phase 2 Clinical Not yet recruiting 1 7 Months 562 Maria C Jimenez-Martínez, MD PhD, Maricarmen Sánchez-Leon, MD, Maricarmen Sánchez-León, MD, Melissa I Espinosa-Navarro, MD, Sonia Mayra Pérez-Tapia, PhD, Toni A Homberg von Thaden, MD, Toni A Homberg, MD 2020-05-11
Social Media and Covid19 Pandemic Coronavirus disease 19 infection survey alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Acibadem University Turkey 2020-05-01 2020-05-08 ACIBADEMU SOCIAL MEDIA, NCT04378738 Phase Not Applicable Recruiting 2 212 2020-05-11
A clinical trial to investigate and define the molecular mechanisms of SARS-CoV-2 infection and COVID-19 and identify targets for medicines and vaccines Coronavirus disease 19 infection Institute For Systems Biology, Merck & Co Inc 10X Technologies Inc, Adaptive Biotechnologies Corp, Andy Hill CARE Fund, Biomedical Advanced Research and Development Authority (BARDA), Bloodworks Northwest, Isoplexis Corp, M.J. Murdock Charitable Trust, Metabolon Inc, NanoString Technologies Inc, Parker Institute for Cancer Immunotherapy, Scisco Genetics Inc, Stanford University, Swedish Hospital, Wilkes University Phase Not Applicable Status not specified 0 200 Dr. Jason D. Goldman 2020-05-08
Efficacy of Liu-zi-jue in patients with 2019 novel Coronavirus pneumonia (COVID-19): a randomized, controlled trial Coronavirus disease 19 infection, Viral pneumonia Liu-zi-jue alone, conventional treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Shanghai University of Traditional Chinese Medicine China 2020-02-19 2020-07-31 ChiCTR2000032367, ChiMCTR2000003246 Phase Not Applicable Recruiting 2 5 Months 186 Min Fang, Shuaigpan Zhang 2020-05-11
Lingnan Fire-Needle Therapy Improves the Quality of Life in General Population Under the Pandemic of Novel Coronavirus Pneumonia (COVID-19): A Prospective, Randomized Controlled Trial Coronavirus disease 19 infection, Viral pneumonia lingnan fire needle therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) The first affiliated hospital of Guangzhou university of Traditional Chinese medicine China 2020-04-27 2020-12-31 ChiCTR2000032346, ChiMCTR2000003245 Phase 0 Clinical Recruiting 1 8 Months 120 Guohua Lin, Jingchun Zeng 2020-05-11
Neurologic Manifestations of COVID 19 in Children Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) University of Pittsburgh Johns Hopkins University, University of Utah US 2020-04-29 2022-12-31 NCT04379089, STUDY20040154 Phase Not Applicable Recruiting 0 32 Months 500 David Maloney, BS, Ericka L Fink, Ericka L Fink, MD 2020-05-11
COPING: COVID Pandemic Short Interval National Survey Gauging Psychological Distress Acute stress disorder, Coronavirus disease 19 infection Nova Scotia Health Authority Canada 2020-05-31 2022-05-31 COPING, NCT04379063, Temporary REB#25470 Phase Not Applicable Not yet recruiting 1 24 Months 10000 Jonathan Bailey, MD MSc FRCPC 2020-05-12
CovRep: Effector and Regulatory T-Cell Receptor Repertoire Analysis in Patients Affected by COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Assistance Publique Hopitaux de Paris France 2020-05-31 2020-11-30 2020-A01245-34, APHP200544, CovRep, NCT04379466 Phase Not Applicable Not yet recruiting 1 6 Months 60 David KLATZMANN, MD, PhD, Roberta LORENZON, MD 2020-05-12
Rintatolimod and IFN Alpha-2b for the Treatment of Mild or Moderate COVID-19 Infection in Cancer Patients Coronavirus disease 19 infection interferon alfa-2b plus rintatolimod 2,5-Oligoadenylate synthetase stimulator, Interferon alpha ligand modulator, Interferon type I receptor agonist, Ribonuclease stimulator, TLR-3 agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Roswell Park Comprehensive Cancer Center National Cancer Institute US 2020-05-30 2021-04-30 I 659920, I 659920, NCI-2020-02317, NCT04379518, P30CA016056 Phase 1/Phase 2 Clinical Not yet recruiting 0 11 Months 80 Brahm H Segal, Brahm H. Segal 2020-05-11
A phase II study to assess the effect of DW-2008 in the treatment of COVID-19 patients Coronavirus disease 19 infection DW-2008 alone Dong Wha Pharmaceutical Co Ltd 2020-06-30 Phase 2 Clinical Planned 0 2020-05-08
Impact on Anxiety and Motivation of COVID-19 and Predictors of Individual Responses Anxiety disorder, Cognitive disorder, Coronavirus disease 19 infection, Psychiatric disorder Computer task questionnaires alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The National Institute of Mental Health National Institutes of Health Clinical Center US 2020-05-22 2021-02-28 20-M-N112, 999920112, NCT04377100 Phase Not Applicable Not yet recruiting 0 9 Months 500 Monique Ernst, M.D., Morgan Andrews, Ph.D. 2020-05-20
IMPACC: Immunophenotyping Assessment in a COVID-19 Cohort Coronavirus disease 19 infection genome-wide association analysis alone, immunophenotyping alone, serial biological sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Allergy and Infectious Diseases Benaroya Research Center at Virginia Mason, Boston Children's Hospital US 2020-05-01 2021-12-31 DAIT-COVID-19-002, IMPACC, NCT04378777 Phase Not Applicable Recruiting 0 20 Months 2000 Albert C. Shaw, MD, Carolyn S. Calfee, MD, MAS, Charles B. Cairns, MD, Elaine Reed, PhD, Grace McComsey, MD, Kari C. Nadeau, MD, PhD, Lindsey R. Baden, MD, Nadine Rouphael, M.D., Nadine Rouphael, MD, Viviana A. Simon, MD, PhD, William B. Messer, MD, PhD 2020-05-15
Serological Testing for COVID-19 (SARS-CoV-2) in ESKD Coronavirus disease 19 infection, End stage renal disease Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitaire Ziekenhuizen Leuven Belgium 2020-04-23 2022-05-01 NCT04378686, S64000 Phase Not Applicable Recruiting 2 24 Months 500 Annelien Van Der Veen, MD, Bjorn Meijers, MD, PhD, Björn Meijers, Helga Wielandt, Koen Stas, MD 2020-05-13
LDCTiP: LDCT in COVID-19 Pneumonia: a Prospective Moscow Study Coronavirus disease 19 infection, Viral pneumonia Low-dose Chest CT alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Federal State Institution "Medical Radiological Research Center" Russian Federation 2020-05-31 2020-07-31 2020-1, LDCTiP, NCT04379531 Phase Not Applicable Not yet recruiting 1 2 Months 230 Anton Vladzymyrskyy, Ivan Blokhin, Valeria Chernina, Victor Gombolevskiy, PhD 2020-05-12
VOC-COVID: Analysis of Volatile Organic Compounds by Electronic Noses in Hospitalized Patients for an Infection by SARS-CoV-2 (COVID-19) Coronavirus disease 19 infection, Respiratory disease electronic nose alone, volatile organic compounds analysis alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopital Foch France 2020-04-14 2020-11-16 2020-0060, NCT04379154, VOC-COVID Phase Not Applicable Recruiting 1 7 Months 60 Elisabeth Hulier-Ammar, Hélène Salvator 2020-05-12
A randomized clinical trial for the efficacy and safety of aliskiren and nifedipine in novel coronavirus pneumonia (COVID-19) patients with hypertension Coronavirus disease 19 infection, Hypertension, Viral pneumonia aliskiren alone, nifedipine alone, standard care alone Calcium channel inhibitor L-type, Renin inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) West China Hospital China 2020-03-01 2020-12-31 ChiCTR2000032314 Phase 0 Clinical Recruiting 5 10 Months 242 Fengming Luo, Min Zhu 2020-05-11