Last updated: May 25, 2020 - 02:00 BST
| A study to determine if a new COVID-19 vaccine safely generates protective immune responses in adults in Kenya |
Coronavirus disease 19 infection |
AZD-1222 alone |
COVID19 Spike glycoprotein modulator |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
University of Oxford |
Wellcome Trust For Human Genetics |
Kenya |
2020-05-31 |
2022-05-31 |
PACTR202005681895696 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
24 Months |
400 |
George Warimwe, Marianne Munene, Philip Bejon |
2020-05-22 |
| Folic acid: A new suggested prevention and treatment of COVID-19 infection |
Coronavirus disease 19 infection |
folic acid alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cairo University |
|
Egypt |
2020-04-20 |
2020-05-21 |
PACTR202005599385499 |
Phase Not Applicable |
Not yet recruiting |
1 |
1 Month |
60 |
Ahmed Farag, Hala Salah, Nadia Ouda |
2020-05-22 |
| SARS-CoV-2 in Personal Protective Equipment |
Coronavirus disease 19 infection |
|
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Jose de San Martin Hospital de Clinicas |
|
Argentina |
2020-05-15 |
2020-07-30 |
NCT04398043, RT PCR EN EPP |
Phase Not Applicable |
Not yet recruiting |
1 |
2 Months |
16 |
Bernardo Bergroth, Bernardo bergroth, MD, Claudio Yaryour, MD |
2020-05-22 |
| An Investigation of the Efficacy and Safety of Favipiravir in COVID-19 Patients without Pneumonia − An open-label, randomized, controlled study |
Coronavirus disease 19 infection |
favipiravir alone, supportive care alone |
RNA polymerase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Faculty of Medicine Siriraj Hospital, Mahidol University, Health System Research Institute (HSRI) |
|
Thailand |
2020-06-01 |
|
TCTR20200514001 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
96 |
Rujipas Sirijatuphat |
2020-05-22 |
| Euro-COVIMID: Prevalence and Seroconversion of COVID-19 in Autoimmune Diseases in Europe |
Autoimmune disease, Coronavirus disease 19 infection, Rheumatoid arthritis, Sjoegrens syndrome, Spondylarthritis, Systemic lupus erythematosus, Temporal arteritis |
serological test alone, usual care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hopital Universitaire de la Pitie Salpetriere |
Groupe d'Études et de Recherche de l'Appareil Locomoteur (GERPAL), Rheumazentrum Ruhrgebiet, Universidad Complutense de Madrid, University College London, University of Coimbra, University of Ferrara |
France |
2020-05-31 |
2020-12-31 |
2020-A01371-38, Euro-COVIMID, NCT04397237 |
Phase Not Applicable |
Not yet recruiting |
1 |
7 Months |
3600 |
David Saadoun, MD, PhD, Laure Gossec, MD, PhD |
2020-05-22 |
| Open, randomized, multicenter, comparative study of the efficacy and safety of the drug AREPLIVIR, film-coated tablets (OOO PROMOMED RUS, Russia) in patients hospitalized with COVID-19 |
Coronavirus disease 19 infection |
favipiravie (Areplivir), Promomed Rus alone |
|
|
Promomed Rus |
|
Russian Federation |
2020-05-21 |
2020-12-31 |
FAV052020 |
Phase 3 Clinical |
Status not specified |
5 |
7 Months |
210 |
|
2020-05-22 |
| Multicenter, open-label, randomized trial of the efficacy and safety of TL-FVP-t compared to standard therapy in parallel groups in patients with mild to moderate coronavirus infection (SARS-CoV-2/COVID-19) |
Coronavirus disease 19 infection |
favipiravir (TL-FVP-t), Technology of Medicines alone |
|
|
Technology of Medicines LLC |
|
Russian Federation |
2020-05-20 |
2022-12-31 |
TL-FVP-t-01 |
Phase 3 Clinical |
Status not specified |
7 |
31 Months |
200 |
|
2020-05-22 |
| BEAT COVID-19: Randomised clinical trial of interventions for the treatment of COVID-19 in the community setting for high risk older people |
Coronavirus disease 19 infection |
hydroxychloroquine alone |
|
Middle-aged Adults (45-64 yrs) |
University of Sydney |
National Health and Medical Research Council |
Australia |
2013-08-03 |
|
ACTRN12620000566932, BEAT COVID-19 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
3000 |
Ms Kate Wilson, Prof Guy Marks |
2020-05-22 |
| An international, multicenter, adaptive, randomized, open, controlled trial to evaluate the efficacy and safety of radotinib in the treatment of hospitalized patients with SARS-CoV-2 coronavirus infection (COVID-19) |
Coronavirus disease 19 infection |
radotinib alone |
Abl tyrosine kinase inhibitor, Bcr protein inhibitor, Tyrosine protein kinase ABL1 inhibitor |
|
Il-Yang Pharmaceutical Co |
|
Russian Federation |
2020-05-14 |
2021-04-30 |
CL01072079 |
Phase 3 Clinical |
Status not specified |
8 |
11 Months |
180 |
|
2020-05-22 |
| ACT-20 in Patients With Severe COVID-19 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
ACT-20 alone, Conventional treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Aspire Health Science LLC |
|
|
2020-05-31 |
2020-10-31 |
AHS 20-03, NCT04398303 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
0 |
5 Months |
70 |
Laura Fairbairn |
2020-05-22 |
| ECMO-SARS: Extracorporeal Membrane Oxygenation (ECMO) and Coronavirus Disease (COVID) 19 |
Cardiac failure, Coronavirus disease 19 infection, Respiratory distress syndrome |
extracorporeal membrane oxygenation therapy alone |
|
|
Rennes University Hospital |
|
France |
2020-04-21 |
2020-10-21 |
35RC20_8979 ECMO-SARS, ECMO-SARS, NCT04397588 |
Phase Not Applicable |
Recruiting |
41 |
6 Months |
300 |
Alexandre OUATTARA, Professor, Alizée Porto, Doctor, André Vincentelli, Professor, André Vincentelli, professor, Antoine Guillon, Doctore, Bernard Cholley, Professor, Bertrand Rozec, Doctor, Bruno Levy, Professor, Claire Roger, Doctor, Claudio Barbanti, Doctor, Corentin Lacroix, Doctor, Cyril Cadoz, Doctor, Cécile Ferragu, DRI, Emmanuel Besnier, Doctor, François Labaste, Doctor, Guillaume Flicoteaux, Doctor, Gwenhaël COLIN, Doctor, Jean-Luc. Fellahi, Professor, Jerome Jouan, Doctor, Jordi Matiello, Doctor, Kais Brini, Doctor, Lucie Gaide-chevronnay, Doctor, Marc-Olivier FISCHER, Professor, Matthias CASTANIER, doctor, Nicolas Allou, Doctor, Nicolas BISCHOFF, Doctor, Nicolas D'OSTREVY, Doctor, Nicolas Mongardon, Doctor, Nicolas Nesseler, Doctor, Nicolas Nesseler, doctor, Olaf Mercier, professor, Olivier DESEBBE, Doctor, Olivier Fabre, Doctor, Olivier Fouquet, Doctor, Olivier Huet, professor, Philippe Gaudard, Doctor, Pierre Fillatre, Doctor, Pierre Guinot, Doctor, Pierre-Emmanuel Falcoz, Professor, Roxane NICOLAS, Sophie Provenchère, Doctor, Stéphane Aubert, Doctor, Vito Giovanni Ruggieri, Professor, Yannick Fedun, Doctor |
2020-05-22 |
| Myocardial Injury and Major Adverse Outcomes in Patients With COVID-19 |
Coronavirus disease 19 infection, Heart injury |
|
|
|
Mount Sinai Medical Center |
|
US |
2020-05-31 |
2022-03-31 |
GCO 20-0965, NCT04397939 |
Phase Not Applicable |
Not yet recruiting |
2 |
22 Months |
5000 |
Annapoorna Kini, MD, Yuliya Vengrenyuk, PhD |
2020-05-22 |
| CO-QUETTES: COVID-19: Study of Inflammasome and Platelets Functions |
Coronavirus disease 19 infection, Viral pneumonia |
blood sampling alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire de Toulouse |
|
France |
2020-04-16 |
2021-04-30 |
CO-QUETTES, NCT04397822, RC31/20/0142 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
60 |
Fanny BOUNES |
2020-05-22 |
| NO-COVER: iNOPulse for COVID-19 |
Coronavirus disease 19 infection, Hypoxia, Viral pneumonia |
nitric oxide (inhaled, INOpulse), Bellerophon plus oxygen |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Miami |
Bellerophon Therapeutics LLC |
US |
2020-07-01 |
2021-01-15 |
20200449, NCT04398290, NO-COVER |
Phase 2 Clinical |
Not yet recruiting |
1 |
6 Months |
30 |
Roger A Alvarez, D.O. |
2020-05-22 |
| Intensive Care Associated Complications and Outcome of Acute Respiratory Distress Syndrome Due to SARS-CoV-2 |
Adult respiratory distress syndrome, Coronavirus disease 19 infection, Myopathy |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Inselspital, Berne |
|
Switzerland |
2020-04-09 |
2021-12-31 |
2020-00730, NCT04397172 |
Phase Not Applicable |
Recruiting |
1 |
20 Months |
50 |
Nicole Söll, Nicoles Söll, Werner Z`Graggen, MD |
2020-05-22 |
| Nebulized Heparin for the Treatment of COVID-19 Induced Lung Injury |
Adult respiratory distress syndrome, Coronavirus disease 19 infection, Lung injury |
nebulized heparin alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Frederick Memorial Hospital |
|
US |
2020-06-01 |
2020-12-31 |
FHHEP518, NCT04397510 |
Phase 4 Clinical |
Not yet recruiting |
1 |
7 Months |
50 |
Thomas Smoot, Thomas Smoot, PharmD |
2020-05-22 |
| PSYCOV-CV: Psychological Impact of COVID-19 Quarantine and Worsening of Cardiovascular Risk in the French General Population |
Acute stress disorder, Anxiety disorder, Cardiovascular disease, Coronavirus disease 19 infection, Depression |
|
|
Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire de Toulouse |
|
France |
2020-04-17 |
2021-04-20 |
NCT04397835, PSYCOV-CV, RC31/20/0135 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
800 |
Emilie Bérard, Emilie Bérard, MD PhD, Emilie Bérard, MD, PHD |
2020-05-22 |
| Mobile Health Study and Enhanced Symptom Monitoring in COVID-19 Cancer Patients |
Cancer, Coronavirus disease 19 infection |
chemotherapy alone, mHealth app alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Oklahoma |
|
US |
2020-06-30 |
2021-12-31 |
COVID-19 MOBILE HEALTH, NCT04397614 |
Phase Not Applicable |
Not yet recruiting |
1 |
18 Months |
500 |
Katherine Moxley, MD, Lead Oncology Nurse, Michael Businelle, PhD |
2020-05-22 |
| RT-PCR on Conjunctival Sample for the Detection of SARS-CoV-2 in Patients With Covid-19 |
Conjunctivitis, Coronavirus disease 19 infection |
Conjunctival RT PCR alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Versailles University Hospital |
|
France |
2020-05-15 |
2020-11-15 |
NCT04397666, P20/09, P20/09_COVEYES |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
68 |
Edouard KOCH, Edouard KOCH, coordonator investigator |
2020-05-22 |
| COVID3T: SARS-CoV-2 Thales Thermography Triage: Thermal Camera Feasibility Study |
Coronavirus disease 19 infection |
thermal camera alone, thermography alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
NHS Greater Glasgow and Clyde |
|
UK |
2020-05-20 |
2020-07-01 |
COVID3T, INGC20AE209, NCT04397380 |
Phase Not Applicable |
Not yet recruiting |
1 |
1 Month |
100 |
Barry Connor, PhD, Dan Forbes, MBChB, David J Lowe, MBChB, David Lowe, MBChB, Iain D Carrie, PhD, Malcolm WG Gordon, MBChb |
2020-05-22 |
| COMBAT-19: Mavrilimumab in Severe COVID-19 Pneumonia and Hyper-inflammation (COMBAT-19) |
Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia |
mavrilimumab alone, standard of care alone |
C-reactive protein inhibitor, Chemokine CC22 ligand inhibitor, GM-CSF receptor antagonist, Hemoglobin scavenger receptor antagonist, Metalloprotease-1 inhibitor, Metalloprotease-3 inhibitor, Small inducible cytokine A17 ligand inhibitor, VEGF gene inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ospedale San Raffaele |
|
Italy |
2020-05-22 |
2020-11-22 |
COMBAT-19, COMBAT-19, NCT04397497 |
Phase 2 Clinical |
Not yet recruiting |
3 |
6 Months |
50 |
Giacomo De Luca, MD, Lorenzo Dagna, MD |
2020-05-22 |
| CACOVID-19: The GCO-002 CACOVID-19 Cohort: a French, Nationwide, Multicenter Study of COVID-19 Infected Cancer Patients |
Anal tumor, Appendix adenoma, Biliary cancer, Bladder cancer, Brain tumor, Breast tumor, Central nervous system tumor, Colorectal tumor, Coronavirus disease 19 infection, Endometrioid carcinoma, Esophagus tumor, Gastrointestinal stromal tumor, Gastrointestinal tumor, Genitourinary tract tumor, Head and neck tumor, Larynx tumor, Liver tumor, Mesothelioma, Mouth tumor, Nasal cancer, Nasopharyngeal carcinoma, Neuroendocrine tumor, Non-small-cell lung cancer, Ovary tumor, Pancreas tumor, Peritoneal tumor, Pharynx tumor, Prostate tumor, Renal tumor, Salivary gland cancer, Skin cancer, Small intestine cancer, Small-cell lung cancer, Stomach tumor, Urinary tract tumor, Uterine cervix tumor, Vulvar intraepithelial neoplasia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Federation Francophone de Cancerologie Digestive |
ARCAGY/ GINECO GROUP, Association des Neuro-OnCologues d'Expression Francaise, Groupe Cooperateur Multidisciplinaire en Oncologie, Groupe Oncologie Radiotherapie Tete et Cou, IFCT |
France |
2020-04-03 |
2020-09-01 |
CACOVID-19, GCO002 CACOVID-19, NCT04397575 |
Phase Not Applicable |
Recruiting |
5 |
4 Months |
1000 |
Anne-Laure PELLETIER, Arnaud BOUTAN-LAROZE, Astrid LIEVRE, PhD, Carole VITELLIUS, Cécile GIRAULT, Gaël GOUJON, Jean-Baptiste BACHET, Julie PHILIP, O. Bouche, MD, Olivier LELEU, Touraj MANSOURBAKHT |
2020-05-22 |
| Blood Collection Study From COVID-19 Convalescents to Identify Immunogenic Viral Epitopes |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
TScan Therapeutics Inc |
|
US |
2020-04-09 |
2020-07-31 |
1586788, NCT04397900 |
Phase Not Applicable |
Recruiting |
2 |
3 Months |
80 |
Abby Richardson, Joana Achanfuo-Yeboah, CRA, Kenneth J Olivier, PhD |
2020-05-22 |
| Efficacy of Early Prone Positioning in Non-Mechanical Ventilation novel coronavirus pneumonia (COVID-19) Patients with Severe Hypoxia- a single-center prospective cohort study |
Coronavirus disease 19 infection, Hypoxia, Viral pneumonia |
prone position alone |
|
|
Tongji Medical College |
|
China |
2020-02-01 |
2020-03-31 |
ChiCTR2000033053 |
Phase 0 Clinical |
Completed |
1 |
2 Months |
60 |
Zang Xuefeng |
2020-05-22 |
| Effect of high dose intravenous vitamin C on moderate novel coronavirus pneumonia (COVID-19) patients: a medical records based retrospective study |
Coronavirus disease 19 infection, Viral pneumonia |
vitamin C alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Rui Jin Hospital |
|
China |
2020-01-01 |
2020-06-30 |
ChiCTR2000033050 |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
110 |
Bing Zhao, Enqiang Mao |
2020-05-22 |
| A clinical study for the efficacy and safety of artemisinin-pipequine tablets in the treatment of the mild or common type novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
artemisinin-piperaquine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Hongqi hospital of Mudanjing medical university |
Guangzhou University of Traditional Chinese Medicine |
China |
2020-05-19 |
2020-12-31 |
ChiCTR2000033049 |
Phase 4 Clinical |
Not yet recruiting |
1 |
7 Months |
|
Fengjie Xie, Hongying Zhang |
2020-05-22 |
| RECAP: Remote Monitoring of Cancer Patients With Suspected Covid-19 |
Coronavirus disease 19 infection, Hematological neoplasm, Sepsis, Solid tumor |
biosensor monitoring alone, continuous physiological ambulatory monitoring alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The Christie NHS foundation trust |
|
UK |
2020-06-30 |
2020-10-31 |
CFTSP186, NCT04397705, RECAP |
Phase 1 Clinical |
Not yet recruiting |
1 |
4 Months |
30 |
John Radford, Wes Dale |
2020-05-22 |
| COVID-19 PEP- High-risk Individuals in Long-term and Specialized Care - Canada |
Coronavirus disease 19 infection |
hydroxychloroquine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Lawson Health Research Institute |
|
Canada |
2020-05-19 |
2021-04-30 |
9881, NCT04397328 |
Phase 3 Clinical |
Not yet recruiting |
1 |
11 Months |
336 |
Michael J Borrie, MB ChB |
2020-05-22 |
| A clinical study of anti-SARS-CoV-2 mRNA lipid nanoparticle vaccine for the prevention of COVID-19 infection |
Coronavirus disease 19 infection |
anti-SARS-CoV-2 mRNA lipid nanoparticle vaccine (COVID-19), CanSino Biologics/ Precision NanoSystems alone |
|
|
CanSino Biologics Inc, Precision NanoSystems Inc |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-05-22 |
| Efficacy and Safety of COVID-19 Convalescent Plasma |
Coronavirus disease 19 infection |
anti SARS-CoV-2 convalescent plasma alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Institute for Transfusion Medicine of RNM |
University clinic of infectious diseases |
|
2020-04-30 |
2021-04-29 |
ITM05/2020MKD, NCT04397523 |
Phase 2 Clinical |
Recruiting |
0 |
12 Months |
20 |
Rada Grubovic Rastvorceva, MD MSci PhD, Sedulla Useini, MD |
2020-05-22 |
| A clinical study to assess the efficacy of Axen COVID-19 RT in detecting COVID-19 infection |
Coronavirus disease 19 infection |
Axen COVID-19 RT alone |
|
|
Macrogen Inc |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
|
|
2020-05-22 |
| A clinical study of AT-100 for the treatment of COVID-19 infection |
Coronavirus disease 19 infection |
AT-100, Airway alone |
Lung surfactant associated protein D modulator |
|
Airway Therapeutics LLC |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-05-22 |
| Phase I/II Clinical Trial of Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector) (Ad5-nCoV) in Canada |
Coronavirus disease 19 infection |
Ad5-nCoV alone |
COVID19 Spike glycoprotein modulator |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
CanSino Biologics Inc, Canadian Center for Vaccinology, Canadian Immunization Research Network, National Research Council of Canada |
Institute of Biotechnology the Academy of Military Medical Sciences PLA |
Canada |
2020-05-31 |
2021-08-31 |
AD5-NCOV-2020003, NCT04398147 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
15 Months |
696 |
Helen H Mao, PhD/MBA, Joanne M Langley, MD, Scott A Halperin, MD |
2020-05-22 |
| CCOVID-PREG: Characteristics of COVID-19 Infection Among Pregnant Women |
Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia |
RT-PCR test alone |
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Inova Health Care Services |
|
US |
2020-05-30 |
2021-03-17 |
CCOVID-PREG, NCT04398264, U20-05-4055 |
Phase Not Applicable |
Not yet recruiting |
1 |
9 Months |
100 |
Luis M Gomez, MD. MScE, Luis M. Gomez |
2020-05-22 |
| Inhaled NO for the Treatment of COVID-19 Caused by SARS-CoV-2 (US Trial) |
Coronavirus disease 19 infection |
LungFit system, Beyond Air alone, nitric oxide alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Beyond Air Ltd |
|
US |
2020-05-18 |
2020-09-30 |
BAI_COV19_01_US, NCT04397692 |
Phase 2 Clinical |
Not yet recruiting |
1 |
4 Months |
20 |
Ashik Tal, MD, Enoch Bortey, Priyantha Wijewardane, Vladislava Zamfirova |
2020-05-22 |
| COVID-19/lactic acid bacteria |
Coronavirus disease 19 infection |
lactic acid bacteria alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Takanawa Pharma KK |
|
Japan |
2020-05-22 |
|
UMIN000040479 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
30 |
Tomoka Ebisui, Tsutomu Nakamura |
2020-05-22 |
| COVID-19 Convalescent Plasma for the Treatment of Hospitalized Patients With Pneumonia Caused by SARS-CoV-2 |
Coronavirus disease 19 infection, Respiratory disease, Viral pneumonia |
COVID-19 convalescent plasma alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Pennsylvania |
|
US |
2020-05-13 |
2020-11-13 |
843003 (PENNCCP-02), NCT04397757 |
Phase 1 Clinical |
Recruiting |
1 |
6 Months |
80 |
Julie Starr, Katharine J. Bar, Katharine J. Bar, MD |
2020-05-22 |
| A clinical trial of ADX-1612 in the treatment of patients with COVID-19 infection |
Coronavirus disease 19 infection |
ganetespib alone |
Hsp 90 inhibitor, Jak2 tyrosine kinase inhibitor, Kit tyrosine kinase inhibitor, STAT-3 inhibitor, STAT-5 inhibitor |
|
Aldeyra Therapeutics Inc |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-05-22 |
| COMET20d: A Study to Collect Bone Marrow for Process Development and Production of BM-MSC to Treat Severe COVID-19 Pneumonitis |
Coronavirus disease 19 infection, Pneumonia |
bone marrow harvest alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs) |
Cambridge Clinical Trials Unit |
Cambridge Cellular Therapies Laboratory, Cambridge University Hospitals NHS Foundation Trust, The Evelyn Trust |
UK |
2020-05-31 |
2021-12-31 |
COMET20D, COMET20d, NCT04397471 |
Phase Not Applicable |
Not yet recruiting |
1 |
19 Months |
10 |
Andrew McCaskie, FRCS, Charles Crawley, MD, Claire Mather, BSc, Purity Bundi, BSc |
2020-05-22 |
| Clinical record investigation about ADHD children because of COVID19 |
Coronavirus disease 19 infection |
|
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Chiba University |
|
Japan |
2020-05-21 |
|
UMIN000040476 |
Phase Not Applicable |
Recruiting |
1 |
|
10 |
Masaomi Iyo, Tsuyoshi Sasaki |
2020-05-22 |
| Effects of nokhod-ab on fatigue |
Coronavirus disease 19 infection, Fatigue |
nokhod-ab alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Semnan University of Medical Sciences |
|
Iran |
2020-05-31 |
|
IR.SEMUMS.REC.1399.031, IRCT20200115046144N2 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
40 |
Ali Gohari, Bahareh Ahadi, Dr. Parviz Kokhaei |
2020-05-22 |
| A phase III, multicenter, randomized, double-blind, placebo-controlled trial to evaluate efficacy and safety of Octagam 10% in patients with severe coronavirus disease |
Coronavirus disease 19 infection |
Octagam 10% alone |
|
|
Octapharma AG |
|
US |
|
|
|
Phase 3 Clinical |
Not yet recruiting |
1 |
|
54 |
|
2020-05-22 |
| RESPOND: Pathogenesis of BTK-mediated Hyper-Inflammatory Responses in COVID-19 |
Coronavirus disease 19 infection |
bruton tyrosine kinase inhibitor therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Institute of Allergy and Infectious Diseases |
National Institutes of Health Clinical Center |
US |
2020-05-28 |
2023-04-30 |
20-I-N114, 999920114, NCT04394884, RESPOND |
Phase Not Applicable |
Recruiting |
2 |
35 Months |
160 |
Ephraim Fuchs, M.D., Joe Roswarski, M.D., Michail S Lionakis, M.D. |
2020-05-23 |
| Combination With Alvelestat and Isotretinoin May Enhance Neutralizing Antibodies in COVID-19 Infected Patients Better Than COVID-19 Inactivated Vaccines (Antibodies) |
Coronavirus disease 19 infection, Respiratory failure, Respiratory tract infection |
alvelestat plus isotretinoin (aerosolized) |
Leukocyte elastase inhibitor |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Kafrelsheikh University |
Damietta University |
Egypt |
2020-06-30 |
2020-11-30 |
COVID-19, NCT04396067 |
Phase 2 Clinical |
Not yet recruiting |
1 |
5 Months |
360 |
M.Sc. Mahmoud Elkazzaz, M.Sc.in Biochemistry, M.Sc.Mahmoud Elkazzaz, Master of biochemistry |
2020-05-22 |
| Physical Activity Levels in COVID-19 Patients Admitted to Intensive Care |
Coronavirus disease 19 infection |
physiotherapy alone, rehabilitation alone, respiratory care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Birmingham NHS Foundation Trust |
|
UK |
2020-03-01 |
2020-05-08 |
NCT04396197, PHYSIOCOVID-19 |
Phase Not Applicable |
Completed |
1 |
2 Months |
92 |
David McWilliams |
2020-05-22 |
| ALLIANCE: International ALLIANCE Study of Therapies to Prevent Progression of COVID-19 |
Coronavirus disease 19 infection |
Variable regimens including Plaquenil , azithromycin , cholecalciferol , mecobalamin , sodium ascorbate , zinc citrate |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Institute of Integrative Medicine |
Catholic Health Initiatives |
Australia |
2020-05-25 |
2021-12-31 |
ALLIANCE, ALLIANCE-COVID19, NCT04395768 |
Phase 2 Clinical |
Not yet recruiting |
1 |
19 Months |
200 |
Karin Ried, PhD, Taufiq Binjemain, MD |
2020-05-22 |
| A Study of ResCure to Treat COVID-19 Infection |
Coronavirus disease 19 infection |
ResCure alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
ProgenaBiome |
Rinati Skin LLC |
US |
2020-05-31 |
2021-10-31 |
NCT04395716, PRG-048 |
Phase 1 Clinical |
Not yet recruiting |
1 |
17 Months |
50 |
Jordan Daniels, MS, Sabine Hazan, MD |
2020-05-22 |
| PAIN-COVID: Early Care Program for the Management of Post-ICU Syndrome and Chronic Pain After COVID-19 Infection |
Anxiety disorder, Coronavirus disease 19 infection, Depression, Pain, Post traumatic stress disorder |
psychological intervention alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Clinic of Barcelona |
|
Spain |
2020-05-25 |
2021-03-25 |
HCB/2020/0549, NCT04394169, PAIN-COVID |
Phase Not Applicable |
Not yet recruiting |
1 |
10 Months |
102 |
Antonio José Ojeda Niño, MD, Tomás Cuñat López, MD |
2020-05-21 |
| Patients Perspectives on Discontinuation of Their Fertility Treatment Due to the COVID-19 Pandemic |
Coronavirus disease 19 infection, Infertility |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Universitair Ziekenhuis Gent |
|
Belgium |
2020-05-14 |
2020-12-31 |
B6702020000247, BC-07783, NCT04396210 |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
2000 |
Frauke Vanden Meerschaut, MD, Rebecca De Beir, Msc |
2020-05-22 |
| Exercise Training and Sedentary Lifestyle on Clinical Outcomes in Patients With COVID-19 |
Coronavirus disease 19 infection |
exercise training alone |
|
Healthy volunteers accepted |
Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo |
|
Brazil |
2020-06-01 |
2021-01-20 |
COVID-19, NCT04396353 |
Phase Not Applicable |
Not yet recruiting |
1 |
7 Months |
850 |
Francis S Ribeiro, PhD, Marcelo R Santos, PhD |
2020-05-21 |
| PPRI: The Professional Peer Resilience Initiative |
Anxiety disorder, Coronavirus disease 19 infection, Post traumatic stress disorder |
MinnRAP peer support program alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Minnesota |
|
US |
2020-05-25 |
2022-05-25 |
NCT04396600, PPRI, STUDY00009564 |
Phase Not Applicable |
Recruiting |
1 |
24 Months |
1200 |
Cristina S Albott, MD, Sey Lee, BS |
2020-05-21 |
| PACCOVRA: Pediatric Acute and Critical Care COVID-19 Registry of Asia |
Coronavirus disease 19 infection |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
KK Women's and Children's Hospital |
Aichi Children's Health and Medical Center, Children's Hospital of Chongqing Medical University, General Hospital H. Adam Malik, Hyogo Prefectural Kobe Children's Hospital, King Chulalongkorn Memorial Hospital, National University Hospital (Singapore) Pte Ltd, Penang General Hospital, Postgraduate Institute of Medical Education and Research, Ramathibodi Hospital, Rumah Sakit Anak dan Bunda Harapan Kita, Singapore Clinical Research Institute, St Marianna University School of Medicine, Tokyo Metropolitan Childrens Medical Center Hospital, Vicente Sotto Memorial Medical Center - Public, Zhengzhou Children's Hospital |
Singapore |
2020-05-18 |
2023-12-31 |
2020/2094, NCT04395781, PACCOVRA |
Phase Not Applicable |
Not yet recruiting |
1 |
43 Months |
2000 |
Cecilia Chandra, Judith Ju Ming Wong |
2020-05-22 |
| Clinical Study for Efficacy of Anti-Corona VS2 Immunoglobulins Prepared From COVID19 Convalescent Plasma Prepared by VIPS Mini-Pool IVIG Medical Devices in Prevention of SARS-CoV-2 Infection in High Risk Groups as Well as Treatment of Early Cases of COVID19 Patients |
Coronavirus disease 19 infection |
Anti-Corona VS2 Immunoglobulins alone, Mini-Pool IVIG alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Assiut University |
|
Egypt |
2020-06-01 |
2021-01-01 |
MINI-POOLED IVIG IN COVID19, NCT04383548 |
Phase 2 Clinical |
Not yet recruiting |
1 |
7 Months |
100 |
Alia M Hussein, professor, Alshaimaa M Selim, specialist, Azza M Ez-Eldin, professor, Magdy El Ekiaby, Doctor, Maha A Mohamed, professor |
2020-05-22 |
| SAVE: A Phase II Study of the C3 Inhibitor AMY-101 in Patients With ARDS Due to COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
AMY-101 alone |
Complement C3 inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Amyndas Pharmaceuticals |
|
|
2020-07-31 |
2021-03-31 |
AMY-101_SAVE, NCT04395456, SAVE |
Phase 2 Clinical |
Not yet recruiting |
0 |
8 Months |
144 |
|
2020-05-21 |
| An Expanded Access Study to Provide at Home Subcutaneous Administration of Pertuzumab and Trastuzumab Fixed-Dose Combination (PH FDC SC) for Patients With HER2-Positive Breast Cancer During the COVID-19 Pandemic |
Breast tumor, Coronavirus disease 19 infection |
pertuzumab + trastuzumab (sc Enhanze, breast cancer), Roche alone |
Erbb2 tyrosine kinase receptor inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Genentech Inc |
|
US |
|
|
AL42478, NCT04395508 |
Phase Not Applicable |
Recruiting |
9 |
|
|
Clinical Trials |
2020-05-22 |
| Home Usability Study of the SARS-CoV-2 Test |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Exact Sciences Corp |
|
US |
2020-05-18 |
2020-06-30 |
2020-06, NCT04395391 |
Phase Not Applicable |
Recruiting |
1 |
1 Month |
30 |
Erin Bork, M.S, Irene Middendorf, Sarah Dunlap, PhD, Steven Shak |
2020-05-21 |
| The effect of hot cupping on corona symptoms |
Coronavirus disease 19 infection |
hot cupping alone, azithromycin plus lopinavir + ritonavir |
HIV protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Mazandaran University of Medical Sciences |
|
Iran |
2020-05-04 |
|
IR.MAZUMS.REC.1399.162, IRCT20131129015584N3 |
Phase 2 Clinical |
Recruiting |
1 |
|
68 |
Assie Jokar, Dr Assie Jokar, Dr Majid Saidi |
2020-05-22 |
| TAC-COVID19: Lung CT Scan Analysis of SARS-CoV2 Induced Lung Injury |
Coronavirus disease 19 infection, Lung injury, Respiratory distress syndrome, Respiratory insufficiency, Viral pneumonia |
CT scan alone, deep learning algorithm-artificial intelligence technology alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Milano-Bicocca |
|
Italy, San Marino |
2020-04-15 |
2020-10-15 |
NCT04395482, TAC-COVID19, TAC-COVID19 |
Phase Not Applicable |
Recruiting |
8 |
6 Months |
500 |
Emanuele Rezoagli, Giacomo Bellani, Giovanni Vitale, Giuseppe Nardi, Luca Lorini, Mario Tavola, Massimo Arlotti, Matteo Subert, Savino Spadaro |
2020-05-22 |
| A phase II study of R-107 for the treatment of severe acute respiratory syndrome in COVID-19 |
Coronavirus disease 19 infection, SARS coronavirus infection |
R-107 alone |
|
|
Massachusetts General Hospital |
|
|
|
|
|
Phase 2 Clinical |
Planned |
0 |
|
|
|
2020-05-21 |
| Dexamethasone for COVID-19 Related ARDS: a Multicenter, Randomized Clinical Trial |
Coronavirus disease 19 infection, Respiratory distress syndrome |
dexamethasone alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centro de Educación Medica e Investigaciones Clínicas Norberto Quirno |
|
Argentina |
2020-05-18 |
2021-01-31 |
1264, NCT04395105 |
Phase 3 Clinical |
Not yet recruiting |
1 |
8 Months |
284 |
Luis P Maskin, MD, Pablo O Rodriguez, MD |
2020-05-21 |
| Sleep Quality in Healthcare Personnel During COVID-19 |
Coronavirus disease 19 infection |
web based online survey alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assiut University |
|
Egypt |
2020-03-30 |
2020-05-16 |
ASSIUTU14, NCT04395300 |
Phase Not Applicable |
Completed |
1 |
1 Month |
143 |
Aliae AR Mohamed Hussein |
2020-05-21 |
| COVIDIV: Collateral Damage From the COVID-19 Pandemic Observed in Patients Treated With Intravitreal Injections (IVT) of Anti-angiogenic Agents |
Coronavirus disease 19 infection, Diabetic macular edema, Retinal venous occlusion, Wet age related macular degeneration |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fondation Ophtalmologique Adolf De Rothschild |
|
France |
2020-05-31 |
2021-12-31 |
COVIDIV, MMT_2020_15, NCT04395859 |
Phase Not Applicable |
Not yet recruiting |
4 |
19 Months |
1500 |
Amélie YAVCHITZ, MD, Benjamin WOLFF, MD, Flore DE BATS, MD, Martine MAUGET FAYSSE, Martine MAUGET FAYSSE, MD, Ramin TADAYONI, MD |
2020-05-22 |
| Sexual Function During COVID-19 Pandemic |
Coronavirus disease 19 infection, Sexual dysfunction |
electronic questionnaire alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs) |
Assiut University |
|
Egypt |
2020-06-01 |
2020-08-31 |
NCT04395885, SFCOV |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
120 |
Ahmed Mohamed Abbas |
2020-05-22 |
| A clinical study of SARS-CoV-2 vaccine (VLP, COVID-19) for the potential prevention of SARS-CoV-2 infection (COVID-19) |
Coronavirus disease 19 infection |
SARS-CoV-2 vaccine (VLP, COVID-19), Medicago alone |
|
|
Medicago Inc |
|
Canada |
2020-08-31 |
|
|
Phase Not Applicable |
Planned |
1 |
|
|
|
2020-05-21 |
| COVID HELMET: Helmet CPAP Versus HFNC in COVID-19 |
Coronavirus disease 19 infection, Respiratory failure |
CaStar hood (Bio-Med Devices) alone, Helmet continuous positive airway pressure therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Lund |
Region Skane |
Sweden |
2020-05-31 |
2021-05-31 |
COVID HELMET, COVID HELMET, NCT04395807 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
120 |
Jonas Tverring, MD, Niklas Nielsen, MD PhD |
2020-05-22 |
| Psychiatric Consultation for COVID-19 Patients |
Coronavirus disease 19 infection, Psychiatric disorder |
psychiatric counseling alone |
|
|
Daegu Catholic University medical center |
|
South Korea |
2020-05-11 |
2020-12-31 |
CR-20-062, NCT04395872 |
Phase Not Applicable |
Not yet recruiting |
1 |
7 Months |
54 |
Jonghun Lee, M.D., ph.D., geunhui Won, M.D. |
2020-05-22 |
| TMF-COVID-19: Maternal-fetal Transmission of SARS-Cov-2 |
Coronavirus disease 19 infection |
RT-PCR SARS-Cov-2 test alone, blood sampling alone, electron microscopy alone, serology test alone, vaginal swab sampling alone |
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Centre Hospitalier Regional D'Orleans |
Centre de Biophysique Moléculaire - Pr Chantal Pichon |
France |
2020-05-05 |
2021-05-31 |
CHRO-2020-10, NCT04395924, TMF-COVID-19 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
50 |
Aurélie DESPUJOLS, Elodie POUGOUE TOUKO, Souhail ALOUINI, Dr |
2020-05-21 |
| A clinical study of S-309 for the potential treatment and/or prevention of SARS-CoV-2 infection (COVID-19) |
Coronavirus disease 19 infection |
SARS-COV-2 targetin human monoclonal antibodies (COVID-19), Vir Biotechnology/ WuXi Biologics alone |
COVID19 Spike glycoprotein inhibitor |
|
Vir Biotechnology Inc |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-05-21 |
| Convalescent Plasma Compared to Anti-COVID-19 Human Immunoglobulin and Standard Treatment (TE) in Hospitalized Patients |
Coronavirus disease 19 infection |
COVID-19 convalescent plasma alone, anti-COVID-19 human immunoglobulin alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Lifefactors Zona Franca, SAS |
|
|
2020-06-30 |
2021-06-30 |
LFCOLCOVID-19-001, NCT04395170 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
0 |
12 Months |
75 |
Santiago Jaramillo |
2020-05-22 |
| TMX COVID: 1,3,7-Trimethylxanthine as a Treatment of COVID-19: Results of a Controlled Study |
Coronavirus disease 19 infection |
coffee containing 1,3,7-trimethylxanthine intake alone, tea and hot chocolate with milk intake alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire De Poitiers Etablissement D’Hospitalisation |
|
|
2020-05-31 |
2020-12-31 |
NCT04395742, TMX COVID, TMX COVID |
Phase Not Applicable |
Not yet recruiting |
0 |
7 Months |
93 |
Alexandre BLEIBTREU, Paul ROBLOT |
2020-05-22 |
| Impact of COVID-19 on Psychological Status in Case of IVF Interrupted or Postponed |
Coronavirus disease 19 infection, Female infertility |
|
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
IRCCS AOU San Martino – IST |
|
Italy |
2020-04-01 |
2020-05-15 |
COVID-19-NOIVF, NCT04395755 |
Phase Not Applicable |
Completed |
1 |
1 Month |
503 |
Fabio Barra |
2020-05-22 |
| ACOVID: Arrhythmias in Patients With COVID-19 |
Coronavirus disease 19 infection, Heart arrhythmia |
C3+ Holter Monitor alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Herlev and Gentofte Hospital, Denmark |
|
Denmark |
2020-04-16 |
2021-04-01 |
ACOVID, H-20021500, NCT04395664 |
Phase Not Applicable |
Recruiting |
1 |
11 Months |
1000 |
Morten Kjøbek Lamberts, MD, PhD, Morten Kjøbæk Lamberts, MD, PhD, Morten Lamberts |
2020-05-22 |
| A phase IIb/III trial to evaluate aviptadil in COVID-19 patients with Acute respiratory distress syndrome |
Coronavirus disease 19 infection, Respiratory distress syndrome |
aviptadil (inhaled, sarcoidosis/acute lung injury/acute respiratory distress syndrome associated COVID-19), Relief Therapeutics Holding alone |
Adrenergic receptor antagonist, VIP receptor agonist |
|
University of California Irvine |
|
US |
|
|
|
Phase 2/Phase 3 Clinical |
Planned |
1 |
|
30 |
|
2020-05-21 |
| Disguise: SARS-CoV-2 Disguise Study |
Coronavirus disease 19 infection |
biological testing alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Meshalkin Research Institute of Pathology of Circulation |
|
Russian Federation |
2020-05-07 |
2020-11-30 |
CS-COVID-19, Disguise, NCT04395794 |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
900 |
Alexander B Romanov, PhD, Denis V Losik, PhD, Dmitry N Ponomarev, PhD, Igor L Mikheenko, Nurlan A Elemesov, Vladimir V Beloborodov, Vladimir V Lomivorotov, PhD |
2020-05-22 |
| A randomized, double-blind, placebo-controlled, Phase II clinical trial designed to determine the clinical efficacy of chloroquine phosphate (CQ) in preventing coronavirus disease 2019 (COVID-19) in healthcare workers with moderate to high risk of exposure to SARS-CoV-2 |
Coronavirus disease 19 infection |
chloroquine phosphate alone |
|
|
Columbia University |
Rising Pharmaceuticals Inc |
US |
|
|
|
Phase 2 Clinical |
Status not specified |
1 |
|
350 |
|
2020-05-21 |
| ECHO: National Survey on the Lockdown of Children With Disabilities |
Coronavirus disease 19 infection, Movement disorder |
|
|
Healthy volunteers accepted, Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
University Hospital, Brest |
|
France |
2020-04-07 |
2020-05-11 |
CHRU DE BREST ECHO, ECHO, NCT04395833 |
Phase Not Applicable |
Completed |
1 |
1 Month |
2500 |
|
2020-05-22 |
| Safety and Efficacy of AT-527 in Subjects With Moderate Coronavirus Disease (COVID-19) |
Coronavirus disease 19 infection |
AT-527 alone, local supportive standard of care alone |
Hepatitis C virus NS5B polymerase inhibitor |
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Atea Pharmaceuticals Inc |
|
US |
2020-05-31 |
2020-08-31 |
AT-03A-001, NCT04396106 |
Phase 2 Clinical |
Not yet recruiting |
10 |
3 Months |
180 |
Clinical Trials Administrator |
2020-05-22 |
| The effect of omega-3 supplementation in COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia |
omega-3 (Omid persina damavand company) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sabzevar University of Medical Sciences |
|
Iran |
2020-06-04 |
|
IR.MEDSAB.REC.1399.054, IRCT20151226025699N3 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
50 |
Dr. Alireza Moslem, Saeid Doaei, Siamak Rimaz |
2020-05-22 |
| A clinical study to assess virosome-based Covid-19 vaccine candidate for the potential treatment of COVID-19 |
Coronavirus disease 19 infection |
SARS-CoV vaccine (protein subunit, COVID-19), Baylor College of Medicine alone |
COVID19 Spike glycoprotein modulator |
|
Mymetics Corp |
Baylor College of Medicine |
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-05-21 |
| Prone Positioning and High-flow Nasal Cannula in COVID-19 Induced ARDS |
Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia |
Prone position alone, high-flow nasal cannula alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Vall D'Hebron |
|
Spain |
2020-05-01 |
2021-06-30 |
NCT04391140, PR(AG)198/2020 |
Phase Not Applicable |
Recruiting |
1 |
14 Months |
248 |
Cesar Laborda, MD, Jordi Riera, MD PhD, Judit Sacanell, MD, Marina García-de-Acilu, MD, Oriol Roca, MD PhD |
2020-05-22 |
| COVID-AKI: Urinary Biomarkers for AKI Diagnosis in Patients With SARS-CoV-2 (COVID-19) |
Coronavirus disease 19 infection, Renal injury |
urinary sampling alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital, Montpellier |
|
France |
2020-03-01 |
2020-06-30 |
COVID-AKI, NCT04393428, RECHMPL20_0294 |
Phase Not Applicable |
Recruiting |
1 |
4 Months |
100 |
Romaric Larcher, MD, PharmD, Romaric Larcher, MD, PharmD, MSc |
2020-05-22 |
| Clinical Use of Stem Cells for the Treatment of COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
allogenic umbilical cord derived-mesenchymal stem cells alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Bakirkoy Dr. Sadi Konuk Research and Training Hospital |
Istinye Universitesi, Liv Hospital (Ulus), Regenerative Medicine and Stem Cell Production Center Liv MedCell |
Turkey |
2020-04-01 |
2020-09-30 |
BAK. SADI KONUK-ISTINYE UNI., NCT04392778 |
Phase 1/Phase 2 Clinical |
Recruiting |
2 |
6 Months |
30 |
Erdal Karaoz, Prof.Dr., Gokhan T Adas, Prof.Dr. |
2020-05-22 |
| TSUNAMI: Transfusion of Convalescent Plasma for the Early Treatment of Patients With COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
convalescent plasma alone, rescue therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Azienda Ospedaliero, Universitaria Pisana |
|
Italy |
2020-05-01 |
2020-10-30 |
NCT04393727, TSUNAMI, TSUNAMI |
Phase 2 Clinical |
Recruiting |
1 |
5 Months |
126 |
Francesco Menichetti, Marco Falcone |
2020-05-22 |
| RHUMACOVID: Drug Management of Rheumatoid Arthritis in COVID-19 Context: Impact on Therapeutic De-escalation |
Coronavirus disease 19 infection, Rheumatoid arthritis |
DMARD therapy management alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital, Brest |
|
France |
2020-04-23 |
2020-05-23 |
NCT04393233, RHUMACOVID, RHUMACOVID (29BRC20.0110) |
Phase Not Applicable |
Recruiting |
1 |
1 Month |
300 |
Dewi GUELLEC, Dewi Guellec, Valerie Devauchelle |
2020-05-21 |
| An Observational Study to Assess the Incidental Findings Suggestive of COVID-19 in Asymptomatic Patients Undergoing Nuclear Medicine Procedures in a High-Prevalence Region |
Coronavirus disease 19 infection |
131-iodine alone, 18F-FDG alone, PET/CT alone, SPECT/CT alone |
|
|
Universita degli Studi di Brescia |
|
Italy |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
77 |
|
2020-05-21 |
| Impact of an Intensified Thromboprofylaxis Protocol in COVID-19 |
Coronavirus disease 19 infection, Deep vein thrombosis, Liver failure, Renal failure |
low molecular weight heparin alone, thromboprophylaxis protocol alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Jessa Hospital |
|
Belgium |
2020-05-04 |
2020-05-15 |
JESSA-20.48, NCT04394000 |
Phase Not Applicable |
Completed |
1 |
|
72 |
|
2020-05-22 |
| Impact of Covid-19 Pandemic on Depression and Quality of Life |
Coronavirus disease 19 infection, Depression |
|
|
Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Okan University |
Yuksek İhtisas University |
Turkey |
2020-05-06 |
2020-05-18 |
56665618-204.01.07, NCT04394078 |
Phase Not Applicable |
Recruiting |
1 |
|
500 |
Begum Okudan |
2020-05-22 |
| Low Dose Radiation Therapy for Covid-19 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
low dose radiation therapy (70 cGy) alone, standard therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
All India Institute of Medical Sciences |
|
India |
2020-06-30 |
2021-06-30 |
COVID-AIIMS, NCT04394793 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
10 |
Daya Nand Sharma, MD, Randeep Guleria, MD, Supriya Mallick, MD |
2020-05-20 |
| SCOPE: Silymarin in COVID-19 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
silymarin alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cairo University |
|
Egypt |
2020-06-01 |
2020-09-30 |
CAIROU COVID-19 STUDY GROUP, NCT04394208, SCOPE |
Phase 3 Clinical |
Not yet recruiting |
1 |
4 Months |
50 |
Khaled Mohammed Korany Salem, Khaled Salem, MSc, Khaled Salem, Msc, Mostafa Alfishawy, Consultant, Mostafa Alfishawy, MD |
2020-05-20 |
| COVID 19 - What Families Think and Do? A Survey for Families Visiting the Pediatric Emergency Department |
Coronavirus disease 19 infection |
|
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
BC Children's Hospital, St Marianna University School of Medicine, University of British Columbia |
|
Japan, Europe, North America |
2020-05-22 |
|
UMIN000040451 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
500 |
Naoki Shimizu, Tomohiro Katsuta |
2020-05-23 |
| Investigation of the effect of intravenous vitamin C on definite patients with coronavirus pneumonia |
Coronavirus disease 19 infection |
Variable regimens including azithromycin , interferon beta , lopinavir + ritonavir , meropenem , vancomycin , vitamin C, Daroupakhsh Company |
HIV protease inhibitor, Penicillin binding protein inhibitor, Peptidoglycan recognition protein inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shaheed Beheshti Medical University |
|
Iran |
2020-04-08 |
|
IR.SBMU.RETECH.REC.1399.067, IRCT20200516047468N1 |
Phase 2/Phase 3 Clinical |
No longer recruiting |
1 |
|
50 |
Afshin Zarghi, Hamideh Moradi Shahr Babak |
2020-05-22 |
| Amotosalen-Ultraviolet A Pathogen-Inactivated Convalescent Plasma in Addition to Best Supportive Care and Antiviral Therapy on Clinical Deterioration in Adults Presenting With Moderate to Severe COVID-19 |
Coronavirus disease 19 infection, SARS coronavirus infection |
INTERCEPT Blood System alone, convalescent plasma alone, standard of care alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
University Hospital Basel |
|
Switzerland |
2020-03-31 |
2020-06-30 |
NCT04389944, REQ-2020-00508, ME20KHANNA2 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
15 |
Andreas Buser, Prof. Dr. MD, Andreas Buser, Prof. Dr. med., Maja Weisser, Prof. Dr. med., Manuel Battegay, Prof. Dr. med., Nina Khanna, Prof. Dr. MD, Nina Khanna, Prof. Dr. med |
2020-05-20 |
| ULTRA-COVID: Ultra Low Doses of Therapy With Radiation Applicated to COVID-19 |
Coronavirus disease 19 infection, Inflammatory disease, Viral pneumonia |
Ventimask alone, nasal cannula alone, oxygen therapy alone, ultra-low-dose radiotherapy (0.8 Gy) alone, Variable regimens including Urbason , azithromycin , hydroxychloroquine (Dolquine) , lopinavir + ritonavir , low molecular weight heparin , piperacillin + tazobactam , tocilizumab |
HIV protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fundacion GenesisCare |
Hospital La Milagrosa, Hospital Vithas Valencia Consuelo |
Spain |
2020-04-21 |
2021-04-21 |
20.4.1597-GHM, NCT04394182, ULTRA-COVID |
Phase 2 Clinical |
Recruiting |
2 |
12 Months |
15 |
Elena Moreno Olmedo, MD, Escarlata López Ramírez, MD, PhD, Luis María Larrea Rabassa, MD, Manuel Pérez Fernández, MD |
2020-05-20 |
| Long Term Functional Outcomes of COVID-19 Patients Treated by Rehabilitation Services viaTelehealth |
Coronavirus disease 19 infection, Viral pneumonia |
rehabilitation program alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Missouri |
|
US |
2020-05-19 |
2022-04-19 |
COVID19RECOVERY, NCT04385901 |
Phase Not Applicable |
Not yet recruiting |
1 |
23 Months |
72 |
Chelsea Harrison, DPT, Jennifer Y Stone, Jennifer Y Stone, PT, DPT, OCS |
2020-05-22 |
| Mir-Age: ABX-464 in Treating Inflammation and Preventing Acute Respiratory Failure in Patients With COVID-19 |
Coronavirus disease 19 infection, Inflammatory disease, Respiratory failure |
ABX-464 alone, standard of care alone |
Rev protein modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Abivax SA |
Bpifrance |
France, Europe |
2020-05-01 |
2021-04-30 |
ABX464-401, Mir-Age, NCT04393038 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
12 Months |
1034 |
Anais Vissian, Eric CUA, MD, Paul GINESTE |
2020-05-20 |
| Using Cord Blood in Treatment of COVID-19 |
Coronavirus disease 19 infection |
cord blood stem cells alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Aljazeera Hospital |
|
Egypt |
2020-05-20 |
2020-08-01 |
COVID -19, NCT04393415 |
Phase 2 Clinical |
Not yet recruiting |
1 |
2 Months |
100 |
Mahmoud Alalfy, PhD |
2020-05-21 |
| Efficacy of Kelofan syrup on COVID-19 |
Coronavirus disease 19 infection |
Kelofan syrup alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ardabil University of Medical Sciences |
|
Iran |
2020-05-17 |
2020-07-05 |
IR.ARUMS.REC.1399.009, IRCT20200405046960N2 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
1 Month |
60 |
Ramin Nasimi Doost Azgomi |
2020-05-21 |
| Longitudinal, COVID-19 Cohort Study |
Coronavirus disease 19 infection, Respiratory failure |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Vermont |
|
US |
2020-04-16 |
2023-05-31 |
CHRMS 16-540, NCT04393155 |
Phase Not Applicable |
Recruiting |
2 |
37 Months |
225 |
Arooj Fatima, Dale Needham, MD, PhD, Renee D Stapleton, MD, PhD, Sara S Ardren, PA |
2020-05-21 |
| COVID19IF: Imaging Feature of SARS-CoV2 Infection |
Coronavirus disease 19 infection |
|
|
|
IRCCS San Raffaele |
|
Italy |
2020-04-16 |
2020-10-01 |
COVID-19 IF, COVID19IF, NCT04394026 |
Phase Not Applicable |
Recruiting |
1 |
5 Months |
500 |
Carlo Martinenghi, MD, Francesco De Cobelli, Francesco De Cobelli, MD, Stephanie Steidler, PhD |
2020-05-20 |
| Serological Testing of Household Contacts of Confirmed Cases of COVID-19 |
Coronavirus disease 19 infection |
COVID-19 IgM/IgG test kit (Singclean) alone, serological test alone |
|
Healthy volunteers accepted, Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Universitario Dr. Jose E. Gonzalez |
|
Mexico |
2020-05-05 |
2020-06-01 |
IF20-00004, NCT04393142 |
Phase Not Applicable |
Recruiting |
1 |
|
92 |
Adrian Camacho, PhD, Adrian Camacho-Ortiz, MD, Adrian Camacho-Ortiz, PhD, Eduardo Pérez Alba, MD, Edurdo Pérez Alba, MD, Gloria Mayela Aguirre García, MD, Jaime Eugenio Espinosa Mora, MD, Laura Marina Nuzzolo Shihadeh, MD |
2020-05-21 |
| COVID_coagulation: Investigation of the predictive value of coagulation parameters for the course of disease in COVID-19 patients |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Johann Wolfgang Goethe-Universitat Frankfurt am Main |
|
Germany |
2020-04-08 |
|
20-627, COVID_coagulation, DRKS00021574 |
Phase Not Applicable |
Recruiting |
1 |
|
1000 |
Wolfgang Prof Miesbach |
2020-05-22 |
| DOCOV: Description of Ophthalmologic Injuries in Intensive Care During the SARS-CoV2 Epidemic - COVID19 |
Coronavirus disease 19 infection, Ocular injury |
Direct exam alone, Shirmer test Retinophotography alone, Slit lamp exam alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fondation Ophtalmologique Adolf De Rothschild |
|
France |
2020-04-27 |
2020-10-31 |
DOCOV, JDS_2020_13, NCT04385810 |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
100 |
Amélie YAVCHITZ, MD, Jean Michel DEVYS, MD, Sophie STEPHAN, MD |
2020-05-22 |
| LUS-COVID19: Lung Ultrasound Score in Covid-19 Infectious Disease in Critical Care |
Coronavirus disease 19 infection, Respiratory distress syndrome |
lung ultrasound (LUS) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire De Nice |
|
France |
2020-03-20 |
2020-12-31 |
20REAMEDCOVID03, LUS-COVID19, NCT04393402 |
Phase Not Applicable |
Recruiting |
1 |
9 Months |
14 |
Jean DELLAMONICA, Jean DELLAMONICA, MD, PhD, Romain LOMBARDI |
2020-05-21 |
| Trial of Imatinib for Hospitalized Adults With COVID-19 |
Coronavirus disease 19 infection |
imatinib alone |
Abl tyrosine kinase inhibitor, Bcr protein inhibitor, Kit tyrosine kinase inhibitor, PDGF receptor antagonist, Signal transduction inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Maryland |
|
US |
2020-05-20 |
2023-06-01 |
2038GCCC, NCT04394416 |
Phase 3 Clinical |
Not yet recruiting |
1 |
36 Months |
204 |
Ashkan Emadi, MD, PhD, Monica Estrada |
2020-05-21 |
| CORMOR: Blood Ozonization in Patients With SARS-CoV-2 Respiratory Failure |
Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure, Respiratory insufficiency, Viral pneumonia |
Blood Ozonization alone, Variable regimens including Hydroxychloroquine , darunavir + cobicistat (fixed dose, HIV infection), Janssen R&D/ Gilead , lopinavir + ritonavir |
Cytochrome P450 3 inhibitor, HIV protease inhibitor, HIV-1 protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Azienda Universitaria Integrata di Udine |
Azienda Ospedaliera Ordine Mauriziano di Torino, Azienda Sanitaria Locale di Vercelli, Celio Military Hospital, Fondazione Toscana Gabriele Monasterio, Ospedale Civile S. Liberatore di Atri, Ospedale Civile di Lucca, Ospedale di Siracusa, University of Siena |
Italy |
2020-04-08 |
2020-10-08 |
CIG: Z7C2CA5837, CORMOR, NCT04388514 |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
90 |
Amato De Monte, Amato De Monte, MD, Carlo Tascini, MD, Emanuela Sozio, MD |
2020-05-22 |
| PROVENT-COVID: Accelerated Prone Position Ventilation of Patients With COVID-19 |
Coronavirus disease 19 infection |
Prone position ventilation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Nordsjaellands Hospital |
|
Denmark |
2020-05-11 |
2020-12-31 |
H-20027361, NCT04384900, PROVENT-COVID |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
150 |
Morten H Bestle, MD, PhD, Morten H Bestle, MD,PhD, Theis S Itenov, MD, PhD, Theis S Itenov, MD,PhD |
2020-05-21 |
| COVID-PRONE: Prone Positioning for Patients on General Medical Wards With COVID19 |
Coronavirus disease 19 infection |
Prone positioning alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
St Michaels Hospital |
Sinai Health System, Sunnybrook Health Sciences Centre, The University Health Network, Toronto General Hospital |
Canada |
2020-05-15 |
2020-12-11 |
2020-1, COVID-PRONE, NCT04383613 |
Phase Not Applicable |
Recruiting |
5 |
6 Months |
350 |
Amol Verma, MD, MPhil, Fahad Razak, MD, MSc, Michael Fralick, MD, PhD |
2020-05-22 |
| CoVInnate: Role of Inflammasomes in COVID-19 Disease |
Coronavirus disease 19 infection |
DNA analysis alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire De Nice |
|
France |
2020-05-11 |
2021-06-12 |
20-PP-07, CoVInnate, NCT04385017 |
Phase Not Applicable |
Recruiting |
2 |
13 Months |
40 |
COURJON JOHAN, PH, COURJON JOHAN, Ph, COURJON Johan, COURJON Johan, Ph, CUA ERIC, PH, Cua Eric, Ph, ROBERT Alexandre, ROBERT Alexandre, Ph |
2020-05-21 |
| Seroprevalence of SARS CoV 2 Antibodies in Previously Undiagnosed Healthcare Workers |
Coronavirus disease 19 infection |
Serologic testing alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Mayo Clinic Foundation |
|
US |
2020-05-06 |
2020-06-12 |
20-004054, NCT04383587 |
Phase Not Applicable |
Recruiting |
1 |
1 Month |
300 |
Mark Parkulo, MD |
2020-05-21 |
| COVIDVIT: Do Vitamin D Levels Really Correlate With Disease Severity in COVID-19 Patients? |
Coronavirus disease 19 infection |
vitamin D alone |
|
|
Bursa City Hospital |
|
Turkey |
2020-05-01 |
2020-06-30 |
1, COVIDVIT, NCT04394390 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
100 |
Taner Dandinoğlu |
2020-05-22 |
| Convalescent Plasma and Placebo for the Treatment of COVID-19 Severe Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
Convalescent SARS COVID-19 plasma alone, standard care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Italiano de Buenos Aires |
|
Argentina |
2020-05-15 |
2020-08-20 |
5565, NCT04383535 |
Phase Not Applicable |
Not yet recruiting |
7 |
3 Months |
333 |
Claudia Salgueira, Esteban Nannini, Fernando Palizas, Florencia Otermin, Francisco Klein, Gustavo Lopardo, Javier Altclas, Javier Sarro, Karina Rainiero, Laura Barcelona, Liliana Sarro, Marcelo Losso, Mariangeles Fenes, Matias Lahitte, Nadia Ahmed, Nora A Fuentes, MD, Pablo Gutierrez, Ricardo Valentini, Santiago Ramirez Borga, Ventura Simonovich, MD, Waldo H Belloso, PhD |
2020-05-22 |
| SINUS WASH: Pilot Study in Adults Testing Positive for COVID-19 |
Coronavirus disease 19 infection |
Betadine alone, Umotif app alone, Videne alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hampshire Hospitals NHS Foundation Trust |
|
UK |
2020-05-31 |
2020-08-31 |
2020-001721-31, NCT04393792, SINUS WASH, SPON-AK-0420 |
Phase 2 Clinical |
Recruiting |
1 |
3 Months |
40 |
Afroze Khan, MBBS MRCS, Chief Investigator, Matthew Dryden |
2020-05-22 |
| TACTIC-E: Multi-arm Therapeutic Study in Pre-ICU Patients Admitted With Covid-19 - Experimental Drugs and Mechanisms |
Coronavirus disease 19 infection, Multiple organ failure |
EDP-1815 alone, standard of care alone, ambrisentan plus dapagliflozin propanediol |
Endothelin ET-A receptor antagonist, Sodium glucose transporter-2 inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cambridge University Hospitals NHS Foundation Trust |
|
UK |
2020-05-20 |
2021-05-20 |
NCT04393246, TACTIC-E, TACTIC-E |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
12 Months |
1407 |
Joseph Cheriyan, MBChB MA FRCP, Sonakshi Kadyan, BTech MRes |
2020-05-21 |
| CLARITY: Controlled evaluation of Angiotensin Receptor Blockers for COVID-19 respiratory Disease |
Coronavirus disease 19 infection, Respiratory disease |
candesartan alone, eprosartan alone, irbesartan alone, losartan alone, olmesartan medoxomil alone, standard care alone, telmisartan alone, valsartan alone |
Angiotensin I receptor antagonist, Angiotensin II AT-1 receptor antagonist, Angiotensin II receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The George Institute for Global Health |
|
Australia |
2020-05-20 |
2021-04-30 |
11052020, CLARITY, NCT04394117 |
Phase 4 Clinical |
Not yet recruiting |
4 |
11 Months |
605 |
Arlen Wilcox, Carol Pollock, Greg Fox, Louisa Sukkar, Meg Jardine |
2020-05-21 |
| HETHICO: Heparins for Thromboprophylaxis in COVID-19 Patients: HETHICO Study in Veneto |
Coronavirus disease 19 infection, Thrombosis |
enoxaparin sodium alone |
Low molecular weight heparin |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Quovadis Associazione |
University of Padua |
Italy |
2020-06-30 |
2020-12-31 |
HETHICO, HETHICO, NCT04393805 |
Phase Not Applicable |
Not yet recruiting |
1 |
6 Months |
877 |
Paolo Simioni, Prof. |
2020-05-22 |
| First Level Socio-geriatric Evaluation: ESOGER Databank |
Coronavirus disease 19 infection, Muscle weakness |
ESOGER questionnaire alone |
|
Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sir Mortimer B Davis Jewish General Hospital |
|
Canada |
2020-04-20 |
2021-04-19 |
MP-05-2021-2308, NCT04393649 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
20000 |
Kevin Galery, Olivier Beauchet, MD |
2020-05-21 |
| KoCo19: Prospective COVID-19 Cohort Munich |
Coronavirus disease 19 infection |
|
|
|
Klinikum der Universitat Muenchen |
Deutsche Forschungsgemeinschaft (DFG), German Federal Ministry of Education and Research, Staatsministerium fur Wissenschaft und Kunst |
Germany |
2020-04-07 |
|
20-275, DRKS00021698, KoCo19 |
Phase Not Applicable |
Recruiting |
1 |
|
6000 |
Michael Hoelscher, Michael Pritsch |
2020-05-21 |
| FACCT: Favipiravir and Hydroxychloroquine Combination Therapy |
Coronavirus disease 19 infection |
favipiravir plus hydroxychloroquine |
RNA polymerase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
King Abdullah International Medical Research Center |
|
Saudi Arabia |
2020-05-31 |
2021-11-30 |
FACCT, NCT04392973, RC20/174 |
Phase 2 Clinical |
Not yet recruiting |
1 |
18 Months |
520 |
Majed Al Jeraisy, Mohammad Bosaeed, Mohammad Bosaeed, MD |
2020-05-21 |
| A trial to assess IBIO-200 for potential treatment of COVID-19 |
Coronavirus disease 19 infection |
IBIO-200 alone |
|
|
iBio Inc |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-05-20 |
| Telepharmacy, inhaler technique, satisfaction, COVID-19 |
Coronavirus disease 19 infection |
telepharmacy counseling alone |
|
|
Hospital Sungai Buloh |
|
Malaysia |
2020-05-15 |
2020-09-30 |
54975, NMRR-20-951-54975 |
Phase Not Applicable |
Status not specified |
1 |
4 Months |
|
MS KALAIVANI A/P SUBRAMANIAM |
2020-05-21 |
| At-Home COVID-19 Antibody Test Usability Assessment and Behavior Change Study |
Coronavirus disease 19 infection |
Premier Biotech COVID-19 IgG/IgM Rapid test Cassette alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
ProofPilot |
Radish Health, Sanesco Bv |
US |
2020-04-05 |
2020-08-29 |
2458, NCT04393961 |
Phase Not Applicable |
Recruiting |
1 |
4 Months |
600 |
Matthew Amsden, Viral Patel, MD |
2020-05-21 |
| TubeObs-Covid: Endotracheal Tube Obstruction in COVID-19 Patients Requiring Mechanical Ventilation |
Coronavirus disease 19 infection |
mechanical ventilation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hopitaux Universitaires de Strasbourg |
|
France |
2020-04-24 |
2020-06-24 |
7803, NCT04394429, TubeObs-Covid |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
184 |
Bob HEGER, MD, Saïd CHAYER, PhD, HDR |
2020-05-21 |
| COVID-Net Validation |
Coronavirus disease 19 infection |
|
|
|
Selayang Hospital |
|
Malaysia |
2020-05-15 |
2020-12-14 |
54941, NMRR-20-949-54941 |
Phase Not Applicable |
Status not specified |
1 |
7 Months |
|
Hafiz Git Kim Ann |
2020-05-21 |
| Lung Irradiation for COVID-19 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
bilateral lung irradiation (100 cGy) alone, single lung irradiation (100 cGy) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Brigham & Women's Hospital |
|
US |
2020-05-31 |
2020-11-30 |
2020P001494, NCT04393948 |
Phase Not Applicable |
Not yet recruiting |
1 |
6 Months |
36 |
David Kozono, MD, PhD, Thomas Johnson, MS |
2020-05-21 |
| COALIZAO ACTION: Full Anticoagulation Versus Prophylaxis in COVID-19 |
Blood clotting disorder, Coronavirus disease 19 infection, Thromboembolism |
azithromycin alone, enoxaparin sodium alone, rivaroxaban alone, routine full anticoagulation strategy therapy alone, unfractionated heparin alone, Variable regimens including azithromycin , enoxaparin sodium , rivaroxaban , unfractionated heparin |
Factor Xa antagonist, Low molecular weight heparin |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Brazilian Clinical Research Institute |
Sociedade Beneficente Israelita Brasileira Hospital Albert Einsten |
Brazil |
2020-05-31 |
2020-12-31 |
002/2020, COALIZAO ACTION, NCT04394377 |
Phase 4 Clinical |
Not yet recruiting |
1 |
7 Months |
600 |
Renato D. Lopes, MD, PhD |
2020-05-21 |
| COVIDsFlt1: sFlt1: a Biomarker of Organ Dysfunction in Critically-ill Patients With COVID-19? |
Coronavirus disease 19 infection, Multiple organ failure, Vascular disease |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire de Reims |
|
France |
2020-03-25 |
2020-09-01 |
COVIDsFlt1, NCT04394195, PO20043* |
Phase Not Applicable |
Recruiting |
1 |
5 Months |
200 |
Damien JOLLY |
2020-05-21 |
| Efficacy of Ivermectin in COVID-19 |
Coronavirus disease 19 infection |
chloroquine plus ivermectin |
Chloride channel modulator |
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Combined Military Hospital, Pakistan |
|
Pakistan |
2020-04-15 |
2020-07-31 |
IVE-COV, NCT04392713 |
Phase 2 Clinical |
Recruiting |
1 |
3 Months |
100 |
Asma Asghar, Asma Asghar, FCPS MED, Karamat Hu Bukhari, FCPS MED, Najma Parveen, FCPS MED, Najma Parveen, FCPS med |
2020-05-21 |
| MaastrICCht: Serial measurements in COVID-19-induced acute respiratory disease to unravel heterogeneity of the disease course: design of the Maastricht Intensive Care COVID cohort |
Coronavirus disease 19 infection |
|
|
|
Maastricht University Medical Center |
|
Netherlands |
2020-03-23 |
2022-03-23 |
MaastrICCht, NL8613 |
Phase Not Applicable |
Recruiting |
1 |
24 Months |
250 |
Bas van Bussel |
2020-05-21 |
| BARICIVID-19: Baricitinib Compared to Standard Therapy in Patients With COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
standard therapy alone, Variable regimens including baricitinib , chloroquine , darunavir + ritonavir , idrossichloroquine , lopinavir + ritonavir , low-molecular weight heparin |
HIV protease inhibitor, Jak1 tyrosine kinase inhibitor, Jak2 tyrosine kinase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Azienda Ospedaliero, Universitaria Pisana |
|
Italy |
2020-05-20 |
2020-07-30 |
BARICIVID-19, BARICIVID-19, NCT04393051 |
Phase 2a Clinical |
Not yet recruiting |
1 |
2 Months |
126 |
Francesco Menichetti, Francesco Menichetti, MD, Giusy Tiseo, MD, Marco Falcone, Marco Falcone, MD |
2020-05-21 |
| Ulinastatin for the Treatment of COVID-19 in Hospitalized Patients |
Coronavirus disease 19 infection |
ulinastatin alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Stanford University |
|
US |
2020-06-30 |
2020-12-31 |
56639, NCT04393311 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
6 Months |
150 |
Kevin V Grimes, MD |
2020-05-21 |
| COVID-19 Wellness Survey |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Rutgers University |
|
US |
2020-05-15 |
2020-05-31 |
NCT04394104, PRO2020001009 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1000 |
Alexandra DelCollo, Alexandra M DelCollo, MS, Sara Elnakib, MPH |
2020-05-21 |
| Hydroxychloroquine in COVID-19 Patients |
Coronavirus disease 19 infection |
hydroxychloroquine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Zagazig University |
|
Saudi Arabia |
2020-03-21 |
2020-08-31 |
NCT04394442, SNH1352020 |
Phase 2 Clinical |
Recruiting |
1 |
5 Months |
200 |
Samah Lutfy, Samah Lutfy, MD, Samah M Lutfy, MD |
2020-05-22 |
| Wearable Sensor to Monitor COVID-19 Like Signs and Symptoms |
Coronavirus disease 19 infection |
ADAM Sensor alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Rehabilitation Institute Of Chicago |
|
US |
2020-04-20 |
2022-12-31 |
NCT04393558, STU00212522 |
Phase Not Applicable |
Recruiting |
1 |
32 Months |
100 |
Arun Jayaraman, Arun Jayaraman, PhD, Lori McGee Koch, Lori McGee Koch, PhD |
2020-05-22 |
| OnCovid: COVID-19 and Cancer Patients |
Cancer, Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Imperial College London |
|
UK |
2020-03-24 |
2022-03-24 |
282140, NCT04393974, OnCovid |
Phase Not Applicable |
Recruiting |
1 |
24 Months |
1000 |
David J Pinato, MD |
2020-05-22 |
| Tetrix: The Critical Care Response to the COVID-19 Pandemic in Madrid |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted |
Hospital Clinico San Carlos |
Instituto de Investigación Sanitaria del Hospital Clínico San Carlos |
Spain |
2020-04-24 |
2020-06-30 |
MADRID COVID TETRIX, NCT04393324, Tetrix |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
2000 |
Antonio S Núñez Reiz, Miguel S Sanchez Garcia, MD, Miguel Sanchez Garcia, MD. PhD, Miguel Sánchez García, MD |
2020-05-21 |
| A clinical study of hydroxychloroquine and azithromycin in the treatment of patients with COVID-19 |
Coronavirus disease 19 infection |
azithromycin alone, hydroxychloroquine alone |
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Oxford |
|
UK |
2020-05-12 |
|
|
Phase Not Applicable |
Recruiting |
1 |
|
|
Chris Butler |
2020-05-20 |
| PIA: COVID-19 Pandemic Impact on Alcohol (PIA): A Natural History Study |
Alcoholism, Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Institute on Alcohol Abuse and Alcoholism |
National Institutes of Health Clinical Center |
US |
2020-05-27 |
2024-12-31 |
20-AA-N115, 999920115, NCT04391816, PIA |
Phase Not Applicable |
Recruiting |
1 |
55 Months |
700 |
Vijay A Ramchandani, Ph.D., Vijay Ramchandani, Ph.D. |
2020-05-22 |
| DICER: Dipyridamole to Prevent Coronavirus Exacerbation of Respiratory Status in COVID-19 |
Blood clotting disorder, Coronavirus disease 19 infection |
dipyridamole alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Michigan |
|
US |
2020-06-30 |
2020-12-31 |
DICER, HUM00179783, NCT04391179 |
Phase 2 Clinical |
Not yet recruiting |
1 |
6 Months |
80 |
Neha Shah, Yogendra Kanthi, MD |
2020-05-20 |
| The Use of Peripheral Blood Specimens From Patients Suspected of Having SARS-CoV-2 Infections in Research Studies Intended to Support the Development of COVID-19 Detection Methods, Treatments, and/or Vaccines |
Coronavirus disease 19 infection |
COVID-19 testing alone |
|
|
Invivoscribe Technologies Inc |
|
US |
2020-06-01 |
2021-06-30 |
IVS-000-002, NCT04391400 |
Phase Not Applicable |
Not yet recruiting |
1 |
13 Months |
500 |
Ellen F Harris, BS, Jason Gerhold, Jordon Thornes |
2020-05-20 |
| Hydroxychloroquine and Ivermectin for the Treatment of COVID-19 Infection |
Coronavirus disease 19 infection, Respiratory tract infection, Viral pneumonia |
hydroxychloroquine plus ivermectin |
Chloride channel modulator |
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centenario Hospital Miguel Hidalgo |
|
Mexico |
2020-05-04 |
2020-09-30 |
2020-A-09, NCT04391127 |
Phase 3 Clinical |
Recruiting |
1 |
4 Months |
200 |
Jose Manuel Arreola Guerra, MD, MSc, PhD, Lucila Martinez, MDPhD, Mario Gonzalez Gamez, MD, Victor Monroy, MD |
2020-05-19 |
| ICMR – RUMC COVID 19: Questionnaire based study of drugs taken by healthcare workers to prevent COVID 19 |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Indian Council of Medical Research |
|
India |
2020-05-18 |
|
CTRI/2020/05/025183, ICMR – RUMC COVID 19 |
Phase Not Applicable |
Not yet recruiting |
15 |
|
5000 |
Dr Bikash Medhi, Dr C D Tripathi, Dr Chetna Desai, Dr Denis Xavier, Dr Dinesh K Badyal, Dr Niyati Trivedi, Dr Pooja Gupta, Dr R Raveendran, Dr S Balakrishnan, Dr Sandeep Kaushal, Dr Sandhya Kamat, Dr Santanu K Tripathi, Dr Sujith Chandy, Dr Suparna Chatterjee, DrHarihar Dikshit |
2020-05-21 |
| Global Snapshot of Covid19 patients with kidney dysfunction |
Coronavirus disease 19 infection, End stage renal disease, Renal injury |
chronic dialysis alone |
|
|
Hospital Kuala Lumpur |
|
Malaysia |
2020-05-15 |
2021-08-11 |
54867, NMRR-20-911-54867 |
Phase Not Applicable |
Not yet recruiting |
9 |
14 Months |
200 |
Dr Ching Chen Hua, Dr EDDIE WONG FOOK SEM, Dr Liu Wen Jiun, Dr Loh Chek Loong, Dr Maisarah Binti Jalalonmuhali, Dr NURUL ZAYNAH BINTI NORDIN, Dr Ruslinda Bt Mustafar, Dr Sunita Bavanandam |
2020-05-20 |
| New Antiviral Drugs for Treatment of COVID-19 |
Coronavirus disease 19 infection |
Variable regimens including ivermectin , nitazoxanide , ribavirin , zinc |
Chloride channel modulator |
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Mansoura University |
|
Egypt |
2020-05-31 |
2022-05-31 |
20.05.69, NCT04392427 |
Phase 3 Clinical |
Not yet recruiting |
1 |
24 Months |
100 |
HATEM ELALFY, HATEM ELALFY, MD, TAREK BESHEER, MD |
2020-05-19 |
| HCQ for COVID-19 |
Coronavirus disease 19 infection |
hydroxychloroquine alone |
|
|
Hospital Kuala Lumpur |
|
Malaysia |
2020-06-01 |
2021-06-01 |
54901, NMRR-20-910-54901 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
450 |
Dr. How Kang Nien |
2020-05-20 |
| Evaluation of the effect of trans sodium crocetinate in respiratory distress caused by COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
standard treatment regimen therapy alone, trans sodium crocetinate alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Mashhad University of Medical Sciences |
|
Iran |
2020-06-21 |
|
IR.MUMS.REC.1399.245, IRCT20081019001369N6 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
30 |
Amirhoushang Mohammadpour, Hossein Hosseinzadeh, Mohsen Tafaghodi |
2020-05-20 |
| HCQ POCKET ECG Ambulatory Telemetry Study |
Coronavirus disease 19 infection |
hydroxychloroquine alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
All India Institute Of Medical Sciences, Rishikesh, MEDICALgorithmics |
|
India |
2020-05-26 |
|
CTRI/2020/05/025216 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
30 |
Rohit Walia |
2020-05-21 |
| Effectiveness of Siddha medicine, Kabasura kudineer and vitamin c-zinc supplementation in the management of Mild COVID 19 patients |
Coronavirus disease 19 infection |
Kabasura Kudineer alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Central Council for Research in Siddha, Government Stanley Medical College Hospital |
|
India |
2020-05-25 |
|
CTRI/2020/05/025215 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
|
50 |
Dr C Anbarasi, Dr S Natarajan |
2020-05-21 |
| A multicenter, randomized, double-blind, placebo-controlled trial for Lu-Dang-Shen oral liquid in the treatment of reduced digestion function of convalescent new coronavirus pneumonia (COVID-19) patient |
Coronavirus disease 19 infection, Indigestion, Viral pneumonia |
Lu-Dang-Shen alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Wuhan third Hospital |
|
China |
2020-05-08 |
2021-05-08 |
ChiCTR2000032919, ChiMCTR2000003304 |
Phase 4 Clinical |
Recruiting |
3 |
12 Months |
200 |
Peng Bo, Qiu tao |
2020-05-22 |
| A randomized controlled trial for the efficacy and safety of artemisinin-pipequine tablets in the treatment of the mild and common type novel coronavirus pneumonia (COVID-19) patients whose nCoV Nucleic acid did not turn negative after treated by hydroxychloroquine and Abidor |
Coronavirus disease 19 infection |
artemisinin + pipequine alone |
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Hongqi hospital of Mudanjing medical university |
Guangzhou University of Traditional Chinese Medicine |
China |
2020-05-07 |
2020-12-31 |
ChiCTR2000032915 |
Phase 4 Clinical |
Recruiting |
1 |
7 Months |
240 |
Fengjie Xie, Hongying Zhang |
2020-05-21 |
| A clinical trial to study the efficacy of convalescent plasma therapy in COVID-19 patients |
Coronavirus disease 19 infection |
convalescent plasma therapy alone |
|
|
Government of India |
Council of Scientific and Industrial Research (India) |
India |
|
|
|
Phase Not Applicable |
Not yet recruiting |
1 |
|
|
Biswanath Sharma Biswas, Shekhar Ranjan Paul, Yogiraj Roy |
2020-05-19 |
| Cold Laser Therapy for COVID-19 Positive Patients With Pulmonary Disease |
Coronavirus disease 19 infection, Lung disease |
MLS laser alone, regular inpatient medical care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Lowell General Hospital |
|
US |
2020-04-30 |
2020-06-30 |
2020.01, NCT04391712 |
Phase 2 Clinical |
Recruiting |
1 |
2 Months |
20 |
Michael McAuliffe, Scott Sigman, MD |
2020-05-20 |
| HCW COVID |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sultanah Nur Zahirah Hospital |
|
Malaysia |
2020-05-28 |
2020-07-31 |
54858, NMRR-20-909-54858 |
Phase Not Applicable |
Not yet recruiting |
1 |
2 Months |
400 |
nurul ashikin binti adnan |
2020-05-21 |
| Traditional Chinese Medicine (TCM); Coronavirus disease 2019 (COVID-19) |
Coronavirus disease 19 infection, Cough |
Traditional Chinese Medicine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
National Cancer Institute - Malaysia |
|
Malaysia |
2020-05-25 |
2020-08-25 |
54907, NMRR-20-940-54907 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
120 |
Dr Teo Chiah Shean |
2020-05-21 |
| Investigating the Effect of BCG Vaccine on Preventing COVID-19 Infection in Healthcare Staff Exposed to SARS-CoV-2 |
Coronavirus disease 19 infection |
BCG vaccine alone, Mantoux Tuberculin alone, tuberculin test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shiraz University of Medical Sciences |
|
Iran |
2020-06-04 |
|
IR.SUMS.REC.1399.181, IRCT20200411047019N1 |
Phase 3 Clinical |
Not yet recruiting |
4 |
|
500 |
Ali Akbari, Bahman Pourabbas, GHolamreza Pouladfar, Gholamreza Pouladfar, Mohsen Moghadami, Mohsen Moghademi |
2020-05-20 |
| Hyperimmune Convalescent Plasma in Moderate and Severe COVID-19 Disease |
Coronavirus disease 19 infection, Viral pneumonia |
convalescent hyperimmune plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Federal Medical Biological Agency |
|
Russian Federation |
2020-05-01 |
2020-09-15 |
COVPLAS-COVID19, NCT04392414 |
Phase 2 Clinical |
Recruiting |
1 |
4 Months |
60 |
Alexander V Averyanov, MD, PhD, Mikhail A Konoplyannikov, PhD, Vladimir P Baklaushev, MD, PhD |
2020-05-20 |
| A clinical trial of BDCA-04 for the treatment of Acute Respiratory Distress Syndrome due to COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
BDCA-04 alone |
|
|
BioCardia Inc |
|
|
|
|
|
Phase not specified |
Status not specified |
0 |
|
|
|
2020-05-19 |
| NIRS-COV: Effects of Cardiovascular and Pulmonary Optimization on Cerebral Oxygenation in COVID-19 Patients With Severe ARDS |
Adult respiratory distress syndrome, Coronavirus disease 19 infection, Hypoxia |
LiDCO alone, near-infrared spectroscopy alone, pulse oxymetry (Massimo) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
HS Hvidovre Hospital |
|
Denmark |
2020-05-01 |
2021-05-01 |
H-20027818, NCT04392089, NIRS-COV |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
20 |
Ana-Marija Hristovska, MD, Ana-Marija Hristovska, MD, Ph.d.-student |
2020-05-19 |
| Hydroxychloroquine, azithromycin and QT-prolongation |
Coronavirus disease 19 infection |
azithromycin plus hydroxychloroquine |
|
|
Taiping Hospital |
|
Malaysia |
2020-05-19 |
2020-05-29 |
55091, NMRR-20-986-55091 |
Phase Not Applicable |
Status not specified |
1 |
|
|
Dr Hor Chee Peng |
2020-05-20 |
| ICPHAM: ICPHAM |
Coronavirus disease 19 infection |
|
|
|
Ministry of Health, Malaysia |
|
Malaysia |
2020-05-25 |
2021-12-31 |
54777, ICPHAM, NMRR-20-989-54777 |
Phase Not Applicable |
Status not specified |
1 |
19 Months |
|
Dr Nur Wahida Binti Zulkifli |
2020-05-20 |
| Phase II, IC14 (Anti-CD14) Treatment in Patients With SARS-CoV-2 (COVID-19) |
Coronavirus disease 19 infection, Lung infection, Respiratory disease, Respiratory failure |
IC-14 alone |
Monocyte differentiation antigen CD14 inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Implicit Bioscience Ltd |
University of Washington |
US |
2020-07-31 |
2021-09-30 |
COV04, NCT04391309 |
Phase 2 Clinical |
Not yet recruiting |
1 |
14 Months |
300 |
Mark Wurfel, MD, PhD |
2020-05-19 |
| Colchicine Plus Phenolic Monoterpenes to Treat COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
standard treatment alone, colchicine plus herbal phenolic monoterpene fractions |
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kermanshah University of Medical Sciences |
|
Iran |
2020-04-01 |
2020-10-01 |
1399.062, NCT04392141 |
Phase 1/Phase 2 Clinical |
Recruiting |
1 |
6 Months |
200 |
Ahmad Bagheri, MSc, Ali Mostafaie, PhD, Alireza Janbakhsh, MD, Farhad Abdali, BSc, Farid Najafi, MD, PhD, Kavyan Fatahpour, MSc, Mohammad H Zamanian, MD, Siavash Vaziri, MD, Yadollah Shakiba, MD, PhD |
2020-05-19 |
| Assessment of boron-containing compounds and Oleoylethanolamide supplementation on the recovery trend in Patients with COVID-19: A double-blind, randomized, placebo-controlled clinical trial |
Coronavirus disease 19 infection |
boron containing compound alone, oleoylethanolamide alone, boron containing compound plus oleoylethanolamide |
|
|
Tabriz University of Medical Sciences |
|
Iran |
2020-05-19 |
|
IR.TBZMED.REC.1399.099, IRCT20090609002017N35 |
Phase 2 Clinical |
Recruiting |
1 |
|
40 |
Alireza Ostadrahimi |
2020-05-20 |
| A clinical trial of TargNaturTa, Off-the-Shelf T Cell Therapy for the prevention of COVID-19 |
Coronavirus disease 19 infection |
TargNaturTa alone |
|
|
Geneius Biotechnology Ltd |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-05-20 |
| BMI-SARSCoV2: Association Between BMI and COVID-19 |
Coronavirus disease 19 infection, Obesity |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Regional Universitaire de Lille |
|
France |
2020-02-01 |
2020-09-30 |
BMI-SARSCoV2, DEC20-095, NCT04391738 |
Phase Not Applicable |
No longer recruiting |
1 |
8 Months |
1200 |
Francois Pattou, MD |
2020-05-21 |
| HYACINTHE: Study Evaluating the Efficacy of Hydroxychloroquine and Azithromycin in Patients With COVID-19 and Hematological Malignancies |
Coronavirus disease 19 infection, Hematological neoplasm |
azithromycin plus hydroxychloroquine |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Institut de Cancerologie Strasbourg Europe |
|
France |
2020-05-12 |
2021-01-31 |
2020-002002-45, 2020-005, HYACINTHE, NCT04392128 |
Phase 2 Clinical |
Not yet recruiting |
1 |
8 Months |
114 |
Anne QUINQUENEL, MD, Bernard DRENOU, MD, Denis CAILLOT, MD, Etienne DAGUINDAU, MD, Luc-Matthieu FORNECKER, MD-PhD, Manon VOEGELIN, Marie Thérèse RUBIO, MD-PhD, Philippe CARASSOU, MD, Stéphanie NGUYEN QUOC, MD-PhD, Valérie SARTORI |
2020-05-21 |
| Effect of colchicine in treatment of COVID-19 |
Coronavirus disease 19 infection |
colchicine plus hydroxychloroquine |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Shahid Sadoughi University of Medical Sciences and Health Services |
|
Iran |
2020-04-04 |
|
IR.SBMU.NRITLD.REC.1399.018, IRCT20190810044500N5 |
Phase 3 Clinical |
Recruiting |
1 |
|
200 |
Dr.Fateme Saghafi, Masoud Mirzaei, Nadia Soltani Gerdefaramarzi, Nadia Soltani gerdefaramarzi |
2020-05-20 |
| LOGIC: The symptoms, virology and immunity of COVID in healthcare workers |
Coronavirus disease 19 infection |
|
|
|
University of Bristol |
The Grand Appeal |
UK |
2020-03-23 |
2021-12-31 |
IRAS 282718, ISRCTN44324934, LOGIC |
Phase Not Applicable |
Recruiting |
1 |
21 Months |
135 |
Prof Finn |
2020-05-20 |
| Therapeutic plasma exchange (removal of the non-cell portion of blood) in critically ill adult patients with serious SARS CoV-2 disease (COVID-19) |
Coronavirus disease 19 infection |
Depuro D2000 Adsorption Cartridge alone, Spectra Optia Apheresis System alone, antibiotics therapy alone, fluid resuscitation alone, mechanical (ARDS-net and prone position) ventilation alone, vasoactive substances therapy alone, hydroxychloroquine plus therapeutic plasma exchange |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
King Saud Medical City |
|
Oman, Saudi Arabia, United Arab Emirates |
2020-04-01 |
2020-12-29 |
ISRCTN21363594, KSMC-IRB-H1R1-29-APR20-01 |
Phase 2 Clinical |
Recruiting |
4 |
8 Months |
|
Dr Fahad Faqihi, Prof Karakitsos |
2020-05-20 |
| RICO: COVID-19 - Study of the Kinetics of the Immune Response During the Intensive Care Unit Stay in Adult Patients Infected With SARS-CoV-2: Multicentric, Non-Interventional Study |
Coronavirus disease 19 infection, Lung disease |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospices Civils De Lyon |
ACCRA |
France |
2020-05-11 |
2021-02-28 |
2020-A01079-30, 69HCL20_0358, NCT04392401, RICO |
Phase Not Applicable |
Recruiting |
7 |
9 Months |
200 |
Anne-Claire LUKASZEWICZ, Pr, Bertrand SOUWEINE, Pr, Carole SCHWEBEL, Pr, Fabienne VENET, Guillaume THIERY, Pr, Hodane YONIS, MD, Laurent ARGAUD, Pr, Marie GROUSSAUD, Thomas RIMMELE, Pr, Vincent PIRIOU, Pr |
2020-05-20 |
| Effect of selenium on covid-19 disease |
Coronavirus disease 19 infection, Respiratory distress syndrome |
standard protocol treatment alone, hydroxychloroquine plus selenium |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ilam University of Medical Sciences |
|
Iran |
2020-04-26 |
|
IR.MEDILAM.REC.1399.010, IRCT20190418043307N1 |
Phase 3 Clinical |
Recruiting |
1 |
|
100 |
Ali Nazari, Elham Shafiei |
2020-05-20 |
| Evaluating Ehe Effects of Umifenovir (Arbidol) in COVID-19 |
Coronavirus disease 19 infection |
Arbidol alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shaheed Beheshti Medical University |
|
Iran |
2020-04-08 |
|
IR.SBMU.RETECH.REC.1399.030, IRCT20151227025726N15 |
Phase 3 Clinical |
Recruiting |
1 |
|
100 |
Afshin Zarghi, Ali Saffaei, Farzaneh Dastan, Payam Tabarsi |
2020-05-20 |
| A clinical study to assess TR-C 19 in the treatment of voluntary COVID-19 patients |
Coronavirus disease 19 infection |
TR-C 19 (COVID-19) VSY Biotechnology/Saglik Bilimleri Universitesi alone |
|
|
VSY Biotechnology |
|
|
|
|
|
Phase Not Applicable |
Not yet recruiting |
0 |
|
|
|
2020-05-20 |
| CTC REGISTRY: Registry of CytoSorb Therapy in COVID-19 ICU Patients |
Coronavirus disease 19 infection, Respiratory failure |
Continuous Renal Replacement Therapy (CRRT) alone, CytoSorb device alone, CytoSorb hemoadsorption alone, Extracorporeal Membrane Oxygenation (ECMO) alone, hemoperfusion extracorporeal circuits alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
CytoSorbents Corp |
|
|
2020-05-31 |
2021-08-31 |
2020-001, CTC REGISTRY, FDA EUA, NCT04391920 |
Phase Not Applicable |
Not yet recruiting |
0 |
15 Months |
1000 |
Ola Ogunsakin, MD, Peter Nelson, MD |
2020-05-20 |
| PROCTOLOCK: Proctologic Practice and Covid-19 |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted |
Societa Italiana di Chirurgia ColoRettale |
Katholieke Universiteit Leuven, Queen Mary University of London, The George Institute for Global Health, Universita' Degli Studi "Magna Graecia" Di Catanzaro, University of Pisa |
Italy |
2020-04-15 |
2020-04-26 |
1, NCT04392245, PROCTOLOCK |
Phase Not Applicable |
Completed |
1 |
|
1050 |
|
2020-05-20 |
| Convalescent Plasma for the Treatment of Severe SARS-CoV-2 (COVID-19) |
Coronavirus disease 19 infection |
convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital San Vicente Fundación |
Clinica de las Americas, Clínica Cardiovid, Clínica Rosario El Tesoro, Clínica Universitaria Bolivariana, Grupo de Inmunodeficiencias primarias Universidad de Antioquia, Hospital Pablo Tobon Uribe |
Colombia |
2020-06-30 |
2021-12-31 |
002, NCT04391101 |
Phase 3 Clinical |
Not yet recruiting |
1 |
18 Months |
231 |
Fabian A Jaimes Barragan, Epidemiol, Fabian Jaimes, Epidemiologi, Oliver G Perilla Suarez, Hematologist, Oliver Perilla Suarez, Hematologist, Oliver Perilla, Hematologist |
2020-05-22 |
| RECOVERY: Resting Energy Expenditure of the Coronavirus (COVID19) Patient in Reanimation Context |
Coronavirus disease 19 infection, Obesity |
indirect calorimetry alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Center D 'Arras |
|
France |
2020-06-01 |
2020-12-31 |
2020-04, NCT04391686, RECOVERY |
Phase Not Applicable |
Not yet recruiting |
1 |
7 Months |
90 |
Kathleen Jacquez, MSc, vincent Florent, MD, PhD, vincent florent, MD, PhD |
2020-05-20 |
| A randomized, placebo-controlled trial to evaluate the effect of two formulations of anti-viral treatment in the reduction of number of COVID-19 patients requiring intensive care treatment |
Coronavirus disease 19 infection |
anti-viral treatment alone |
|
|
Senzer Ltd |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-05-19 |
| COVID19-LLC-MW: Observatory of Patients With Chronic Lymphocytic Leukemia / Lymphocytic Lymphoma or Waldenstrom Disease Infected With COVID-19 |
Chronic lymphocytic leukemia, Coronavirus disease 19 infection, Lymphoplasmacytic lymphoma |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
French Innovative Leukemia Organisation |
Institut de Cancerologie Strasbourg Europe |
France |
2020-06-01 |
2022-12-31 |
COVID19-LLC-MW, FILO-COVID19_LLC-MW, NCT04391946 |
Phase Not Applicable |
Not yet recruiting |
1 |
31 Months |
50 |
Luc-Matthieu FORNECKER, Pr, Raoul HERBRECHT, Pr, Valérie ROUILLE |
2020-05-19 |
| Efficacy of Extract of of Zingiber Cinnamomum and Zataria multiflora in Covid-19 Disease |
Coronavirus disease 19 infection |
Zingiber, Cinnamon zeylanicum and Zataria multiflora extract (Armagan Salamat Zagros Yasuj Company) alone, standard treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Yasouj University of Medical Sciences and Health Services |
|
Iran |
2020-05-21 |
|
IR.YUMS.REC.1399.029, IRCT20081011001323N25 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
|
80 |
Ali Mousavizadeh, Sadrollah Mehrabi |
2020-05-21 |
| A controlled clinical study to assess KB-109 added to supportive self-care (SSC) for outpatients who are positive for SARS-CoV-2 infection with mild-to-moderate COVID-19 |
Coronavirus disease 19 infection |
KB-109 alone, supportive self-care (SSC) alone |
|
|
Kaleido Biosciences Inc |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
50 |
|
2020-05-19 |
| Evaluating the effect of intravenous N-acetylcysteine versus placebo in the treatment of patients with mild and moderate acute respiratory distress syndrome caused by COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
N-acetylcysteine alone, routine care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Hamadan University of Medical Sciences |
|
Iran |
2020-06-04 |
|
IR.UMSHA.REC.1399.153, IRCT20120215009014N355 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
92 |
Dr Abbas Taher, Dr. Maryam Mehrpooya, Dr. Saeid Bashirian |
2020-05-20 |
| A Study of COVID-19 Convalescent Plasma in High Risk Patients With COVID-19 Infection |
Coronavirus disease 19 infection |
convalescent plasma alone |
|
Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
TriHealth |
|
US |
2020-05-05 |
2020-12-31 |
20-045, NCT04392232 |
Phase 2 Clinical |
Recruiting |
2 |
7 Months |
100 |
Thomas E. Coyle, MD, William Judd, MBA, MHA(C.) |
2020-05-21 |
| Oral Manifestation of COVID-19 Patient: A Cross-Sectional Study on Egyptian Population |
Coronavirus disease 19 infection, Mouth ulcer |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cairo University |
|
Egypt |
2020-05-30 |
2020-06-30 |
54678, NCT04391881 |
Phase Not Applicable |
Not yet recruiting |
1 |
1 Month |
500 |
Dina Mounir Elkady, Dina Mounir Elkady, Phd, Rawda Hisham Abdel aziz, Phd |
2020-05-20 |
| TMPRSS2: Mechanism of Covid 19 infection in Humans |
Coronavirus disease 19 infection |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Asian Healthcare Foundation |
|
India |
2020-05-11 |
|
COVID19TMPRSS2, CTRI/2020/05/024989, TMPRSS2 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
200 |
Dr D Nageshwar Reddy, Dr M Sasikala |
2020-05-20 |
| COVIDSPERM: Detection of SARS-CoV-2 in Semen of COVID-19 Positive Males |
Coronavirus disease 19 infection |
PCR alone |
|
Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Universitair Ziekenhuis Brussel |
|
Belgium |
2020-05-12 |
2020-08-31 |
COVIDSPERM, COVIDSPERM, NCT04391829 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
20 |
Michael De Brucker, MD PHD, Valerie Uvin, MD |
2020-05-20 |
| The Sungai Buloh Experience: A Retrospective Study in Olfactory and Taste Disturbance in COVID-19 |
Ageusia, Coronavirus disease 19 infection, Dysgeusia, Dysomia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Hospital Sungai Buloh |
|
Malaysia |
2020-06-01 |
2020-07-08 |
54938, NMRR-20-932-54938 |
Phase Not Applicable |
Not yet recruiting |
2 |
1 Month |
|
Raudha Ezaty binti Ruslan |
2020-05-20 |
| Pregnancy with COVID-19 in Malaysia : A Case Series |
Coronavirus disease 19 infection |
|
|
Female |
Hospital Sungai Buloh |
|
Malaysia |
2020-05-13 |
|
54904, NMRR-20-931-54904 |
Phase Not Applicable |
No longer recruiting |
1 |
|
|
Dr Siti Hayati binti Mohd Nahwari |
2020-05-20 |
| Homeopathy in prevention of COVID-19 |
Coronavirus disease 19 infection |
Arsenicum album alone |
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Central Council for Research in Homoeopathy |
|
India |
2020-05-13 |
|
CTRI/2020/05/024986 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
10000 |
Dr Anil Khurana, Dr Debadatta Nayak, Dr Raj K Manchanda |
2020-05-20 |
| A controlled, multicenter clinical study to assess KB-109 added to supportive self-care (SSC) for outpatients who are positive for SARS-CoV-2 infection with mild-to-moderate COVID-19 |
Coronavirus disease 19 infection |
KB-109 alone, supportive self-care (SSC) alone |
|
|
Kaleido Biosciences Inc |
|
|
2020-05-14 |
|
|
Phase Not Applicable |
Recruiting |
0 |
|
350 |
|
2020-05-19 |
| APDepCOVID19: Antenatal and postpartum depression among Malaysian women treated as covid-19 and its contributory factors |
Coronavirus disease 19 infection, Postnatal depression |
|
|
Female |
Hospital Sungai Buloh |
|
Malaysia |
2020-05-20 |
2020-10-19 |
54717, APDepCOVID19, NMRR-20-917-54717 |
Phase Not Applicable |
Not yet recruiting |
1 |
5 Months |
77 |
Dr Norhana Binti Mohd Kasim |
2020-05-20 |
| Incidence of COVID-19 Test Conversion in Post-surgical Patients |
Coronavirus disease 19 infection, Lower respiratory tract infection |
polymerase chain reaction test alone, serology tests alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Northwell Health Inc |
|
US |
2020-05-13 |
2020-07-31 |
IRB #20-0404, NCT04392323 |
Phase Not Applicable |
Recruiting |
2 |
2 Months |
500 |
Aaron Nizam, MD, Andrew W Menzin, MD, MBA, Bruce Farber, MD, Ernesto Molmenti, MD, PhD, MBA, James Crawford, MD, Jose Prince, MD, Matthew Weiss, MD, Michael Nimaroff, MD, MBA, Santiago Miyara, MD |
2020-05-20 |
| Validity of at Home Visual Acuity Measurements for Telemedicine During Corona Virus (COVID-19) Pandemic |
Coronavirus disease 19 infection, Glaucoma, Uveitis |
non invasive visual acuity testing alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Vanderbilt University Medical Center, US |
|
US |
2020-05-15 |
2022-05-01 |
200826, NCT04391166 |
Phase Not Applicable |
Not yet recruiting |
1 |
23 Months |
150 |
Jeffery Kammer, MD, Megan C Barrett, CPO, Saige Wilkins, COA, Sapna Gangaputra, MD, MPH, Sean Donahue, MD, PHD, Shriji Patel, MD, Sylvia Groth, MD |
2020-05-21 |
| Efficacy and Safety of Itolizumab in COVID-19 Complications |
Coronavirus disease 19 infection |
antibiotics alone, antivirals alone, hydroxychloroquine alone, itolizumab alone, oxygen alone |
T-cell differentiation antigen CD6 inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Biocon Ltd |
|
India |
2020-05-01 |
|
CTRI/2020/05/024959, ITOLI-C19-02-I-00 |
Phase 2 Clinical |
Recruiting |
3 |
|
30 |
Dr Milind Nadkar, Dr Murli Mohan, Dr Shashank Joshi, Dr Subramanian Loganathan, Dr Suresh Kumar, Sivakumar Vaidyanathan |
2020-05-20 |
| Effect of intrapulmonary injection of processed serum derived from Covid-19 patients in reduction of pulmonary complications |
Coronavirus disease 19 infection |
autologous serum alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Tabriz University of Medical Sciences |
|
Iran |
2019-05-05 |
|
IR.TBZMED.REC.1399.014, IRCT20091012002582N21 |
Phase 2 Clinical |
No longer recruiting |
1 |
|
30 |
Ata Mahmoodpoor, Khosro Adibkia, Leila Roshangar |
2020-05-20 |
| IVIG and COVID19 |
Coronavirus disease 19 infection, Lung injury |
Flebogamma DIF 5% alone |
Beta amyloid modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Oroumia University of Medical Sciences |
|
Iran |
2020-05-09 |
|
IR.UMSU.REC.1399.025, IRCT20200501047259N1 |
Phase 3 Clinical |
Recruiting |
1 |
|
40 |
Naser Gharebaghi, Reza Hajizadeh |
2020-05-20 |
| A phase II, open design trial to evaluate KAND-567 in covid-19 patients |
Coronavirus disease 19 infection |
KAND-567 alone, best standard treatment alone |
CX3CR1 chemokine antagonist, Fractalkine ligand inhibitor |
|
Kancera AB |
Capio S:t Görans Hospital, Scandinavian CRO, Scandinavian Development Services AB, Science For Life Laboratory |
Sweden |
|
|
|
Phase 2 Clinical |
Planned |
1 |
|
40 |
|
2020-05-19 |
| Serial, cross-sectional, seroprevalence study of SARS-CoV-2 infection during and after the COVID-19 epidemic in Heidelberg and the Rhein-Neckar region |
Coronavirus disease 19 infection |
blood sampling alone |
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Heidelberg |
SAP SE |
Germany |
2020-05-25 |
|
DRKS00021709, S-279/2020 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1500 |
Claudia Maria Denkinger |
2020-05-20 |
| Intervention |
Coronavirus disease 19 infection, Respiratory tract infection |
hyoscyamus niger methanolic extract plus propolis |
|
|
Kashan University of Medical Sciences and Health Services |
|
Iran |
2020-05-06 |
|
IR.KAMUS.REC.1399.001, IRCT20200516047462N1 |
Phase 2 Clinical |
Recruiting |
1 |
|
50 |
Dr. Hamidreza Banafsheh, Morteza Kosari |
2020-05-21 |
| Study to efficacy of Ivermectin in patients of COVID-19 |
Coronavirus disease 19 infection |
ivermectin alone, standard of care alone |
Chloride channel modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
RD Gardi Medical College |
|
India |
2020-05-24 |
|
CTRI/2020/05/025224 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
50 |
Dr Ashish Pathak, Dr Sunil Rathi |
2020-05-21 |
| COALA: Covid-19 related Obstetric Anesthesia Longitudinal Assessment-Registry |
Coronavirus disease 19 infection |
|
|
Female |
University Hospital Wurzburg |
|
Germany |
2020-03-25 |
|
63/20-kr, COALA, DRKS00021772 |
Phase Not Applicable |
Recruiting |
1 |
|
|
Magdalena Sitter, Peter Kranke |
2020-05-20 |
| Efficacy of Tablet AOIM - Z in Prevention of COVID - 19 in High Risk Healthy Police Personnel |
Coronavirus disease 19 infection |
AOIM - Z alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Shree Dhootapapeshwar Limited |
|
India |
2020-06-01 |
|
CTRI/2020/05/025222 |
Phase 4 Clinical |
Not yet recruiting |
1 |
|
275 |
Dr Mahesh Kumar Harit, Dr Vedvati Bhapkar, Dr Vinay Pawar |
2020-05-21 |
| SAPRIS-SERO: Health, Perception, Practices, Relations and Social Inequalities in the General Population During the Covid-19 Crisis |
Coronavirus disease 19 infection |
dried blood spot sampling alone |
|
Healthy volunteers accepted |
INSERM |
|
France |
2020-05-01 |
2020-12-31 |
2020-A01195-34, C20-26, NCT04392388, SAPRIS-SERO |
Phase Not Applicable |
Recruiting |
1 |
8 Months |
110000 |
Fabrice Carrat, Fabrice Carrat, MD |
2020-05-20 |
| Create registry of Childhood Cancer patients in India with COVID 19 to provide guidelines for prevention and treatment |
Cancer, Coronavirus disease 19 infection |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Max Super Speciality Hospital |
|
India |
2020-05-26 |
|
CTRI/2020/05/025221, InPOG-EPI-20-02 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1000 |
Dr Ramandeep Arora |
2020-05-21 |
| Neuropsychiatric effects of COVID-19 |
Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder |
Neuropsychiatric effects alone |
|
|
University Malaya Medical Centre |
|
Malaysia |
2020-05-18 |
2021-05-18 |
54785, NMRR-20-905-54785 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
|
Dr Tai Mei Ling Sharon |
2020-05-20 |
| A study to evaluate anakinra in patients with severe coronavirus disease 2019 (COVID-19) with pneumonia and sHLH |
Coronavirus disease 19 infection, Hemophagocytic lymphohistiocytosis, Respiratory failure, Viral pneumonia |
antibiotics alone, anakinra plus hydroxychloroquine |
Type I IL-1 receptor antagonist |
|
Cell Press, Hellenic Institute for the Study of Sepsis |
|
Greece, Netherlands |
|
|
|
Phase 2 Clinical |
Status not specified |
2 |
|
8 |
|
2020-05-19 |
| COVID-19 Genome Sequence |
Coronavirus disease 19 infection |
Genome Sequencing alone |
|
|
The National Institute of Public Health Laboratory, Phnom Penh |
|
Malaysia |
2020-05-12 |
2020-12-31 |
54809, NMRR-20-904-54809 |
Phase Not Applicable |
Status not specified |
1 |
7 Months |
|
Dr NOORLIZA BINTI MOHAMAD NOORDIN |
2020-05-20 |
| PICP19: A clinical trial for validating therapeutic efficacy of convalescent plasma in severe COVID-19 disease |
Coronavirus disease 19 infection |
convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Council of Scientific and Industrial Research (India) |
|
India |
2020-05-20 |
|
CTRI/2020/05/025209, PICP19 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
80 |
Dipyaman Ganguly, Dr Biswanath Sharma Sarkar, Yogiraj Ray |
2020-05-21 |
| Arsenicum album-30c as prophylactic for COVID-19 |
Coronavirus disease 19 infection |
arsenicum album-30c alone |
|
Healthy volunteers accepted, Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Central Council for Research in Homoeopathy |
|
India |
2020-05-24 |
|
CTRI/2020/05/025205 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
10 |
|
33000 |
Dr Anil Khurana, Dr Ashish Mahajan, Dr Ch Ravender, Dr Debadatta Nayak, Dr KC Murleedharan, Dr Karthikeyan, Dr Lipipushpa Debata, Dr P Hima Bindu, Dr P P Pal, Dr Ramesh Bawaskar, Dr Subhash Kaushik |
2020-05-20 |
| Siddha interventions prevention to front line workers |
Coronavirus disease 19 infection |
Kabasurakudineer alone, Nilavembukudineer alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Central Council for Research in Siddha |
|
India |
2020-05-22 |
|
CTRI/2020/05/025182 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
366 |
DrPSathiyarajeswaran |
2020-05-22 |
| Evaluation of the Immuno-Stimulatory Potential (Shareera Bala) of an Ayurveda Management Protocol in Cohort of Quarantined Delhi Police under Covid-19 Care Centers- An Exploratory Clinical Study |
Coronavirus disease 19 infection |
Anu taila alone, Variable regimens including Herbal tea , Samshamani Vati , aridra khanda |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
All India Institute of Ayurveda |
|
India |
2020-05-18 |
|
CTRI/2020/05/025178 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
140 |
Dr VG Huddar, PIprof Dr Tanuja Nesari |
2020-05-20 |
| PHOBIC: Mental status of public during lockdown COVID-19 |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Siddha Central Research Institute |
|
India |
2020-05-22 |
|
CTRI/2020/05/025194, PHOBIC |
Phase Not Applicable |
Not yet recruiting |
1 |
|
280 |
Narrain shree S, Vinoth N P |
2020-05-20 |
| PSY: COVID-19: Psychological Impact of COVID-19 Pandemic |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sri Ramachandra Institute of Higher Education and Research |
|
US, India, United Arab Emirates |
2020-05-19 |
|
CTRI/2020/05/025184, PSY: COVID-19 |
Phase Not Applicable |
Not yet recruiting |
3 |
|
1000 |
Dr Vivian Kapil V |
2020-05-20 |
| COVID-19 Long QT: COVID-19 Long QT |
Coronavirus disease 19 infection |
azithromycin alone, chloroquine alone, hydroxychloroquine alone, lopinavir + ritonavir alone, smartphone ECG monitoring alone, Variable regimens including azithromycin , chloroquine , hydroxychloroquine , lopinavir + ritonavir |
HIV protease inhibitor |
|
Sarawak Heart Centre |
|
Malaysia |
2020-05-18 |
2020-05-19 |
54921, COVID-19 Long QT, NMRR-20-975-54921 |
Phase Not Applicable |
Recruiting |
1 |
|
30 |
Dr Koh Keng Tat |
2020-05-20 |
| Clinical trial to assess the prognostic repercussions of rosuvastatin treatment in patients discharged after hospitalization for COVID-19 Positive |
Cardiac failure, Coronavirus disease 19 infection, Deep vein thrombosis, Lung embolism, Myocardial infarction |
rosuvastatin alone |
HMG CoA reductase inhibitor |
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Instituto de Investigación Sanitaria de la Fundacion Jimenez Diaz |
Jimenez Diaz Foundation |
Spain |
2020-05-14 |
|
2020-001319-26, FJD-COVID-ESTATINAS |
Phase 3 Clinical |
Recruiting |
1 |
|
1080 |
CLINICAL RESEARCH UNIT |
2020-05-20 |
| SEN-CoV-Fadj: Efficacy and Safety Evaluation of Treatment Regimens in Adult COVID-19 Patients in Senegal |
Coronavirus disease 19 infection |
azithromycin plus hydroxychloroquine |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Institut Pasteur de Dakar |
Dalal Jamm Hospital, Senegal, Diamniadio Children Hospital, Senegal, Epicentre (MSF), Fann Hospital, Senegal, Ministry of Health, senegal |
Senegal |
2020-06-01 |
2021-06-01 |
2020-002, NCT04390594, SEN-CoV-Fadj |
Phase 3 Clinical |
Not yet recruiting |
3 |
12 Months |
258 |
Abdoul Kane, MD, Aissatou Lakhe, MD, Amadou A. Sall, PhD, Fabien Taieb, MD, PhD, Fatou SD Ndiaye, MD, Khardiata D. Mbaye, MD, Louise Fortes, MD, Maguette N. Fall, MD, Moussa Seydi, MD, Oumar Kane, MD, Pape S. Ba, MD |
2020-05-20 |
| Postpartum Sexual Function in Pregnant Women With COVID-19 |
Coronavirus disease 19 infection, Dyspareunia, Female sexual dysfunction |
|
|
Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Istanbul Bakirkoy Maternity and Children Diseases Hospital |
|
Turkey |
2020-05-14 |
2020-08-03 |
MTALMACCAROL, NCT04389489 |
Phase Not Applicable |
Not yet recruiting |
1 |
2 Months |
140 |
Merve Aldikactioglu Talmac, Merve Aldikactioglu Talmac, M.D. |
2020-05-19 |
| Respiratory Decompensation and Model for the Triage of COVID-19 Patients |
Coronavirus disease 19 infection, Respiratory disease |
COViage alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Dascena |
|
US |
2020-03-24 |
2020-05-30 |
051420, NCT04390516 |
Phase Not Applicable |
No longer recruiting |
1 |
2 Months |
197 |
|
2020-05-18 |
| Front liner children in Covid-19 |
Coronavirus disease 19 infection |
|
|
|
Selayang Hospital |
|
Malaysia |
2020-05-01 |
2020-05-15 |
54970, NMRR-20-908-54970 |
Phase Not Applicable |
Completed |
1 |
|
|
Dr Tang Swee Ping |
2020-05-20 |
| LB-1148 for Pulmonary Dysfunction Associated With COVID-19 Pneumonia |
Coronavirus disease 19 infection, Lung inflammation, Respiratory disease, Viral pneumonia |
tranexamic acid (oral, multiple organ failure), InflammaGen/University of California San Diego alone |
Serine protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Leading BioSciences Inc |
|
|
2020-06-30 |
2021-03-31 |
LBS-COVID19-201, NCT04390217 |
Phase 2 Clinical |
Not yet recruiting |
0 |
9 Months |
120 |
Brian K Wenzel, MS, CCRA, Inge K Bear, MS, CCRA, Michael J Dawson, MD |
2020-05-18 |
| Post-operative Recovery Index, Patient Expectations and Satisfaction With Prenatal Care Instrument in Pregnant Patients With COVID-19 |
Coronavirus disease 19 infection |
optimum postoperative care alone |
|
Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Istanbul Bakirkoy Maternity and Children Diseases Hospital |
|
Turkey |
2020-05-14 |
2020-08-03 |
MTALMAC3, NCT04389515 |
Phase Not Applicable |
Not yet recruiting |
1 |
2 Months |
75 |
Merve Aldikactioglu Talmac |
2020-05-19 |
| TOFACoV-2: Tofacitinib Plus Hydroxychloroquine versus Hydroxychloroquine in Patients With COVID-19 Interstitial Pneumonia |
Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia |
hydroxychloroquine plus tofacitinib citrate (oral, inflammation), Pfizer |
JAK tyrosine kinase inhibitor, Jak1 tyrosine kinase inhibitor, Jak3 tyrosine kinase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Universita Politecnica delle Marche |
ASST Cremona, ASST Papa Giovanni XXIII, Azienda Ospedali Riuniti Marche Nord, Azienda Policlinico Umberto I, Fondazione IRCCS Ca' Granda-Ospedale Maggiore Policlinico, Hospital S. Spirit, Regional Hospital, Varese, Italy, Università Magna Grecia |
Italy |
2020-06-30 |
2020-10-31 |
2020-002035-30, NCT04390061, TOFACoV-2 |
Phase 2 Clinical |
Not yet recruiting |
1 |
4 Months |
116 |
Armando Gabrielli, Armando Gabrielli, MD |
2020-05-21 |
| The impact of Program Kesihatan Optimum (Pohon Sihat) on COVID-19 patients during COVID-19 pandemic |
Coronavirus disease 19 infection |
Program Kesihatan Optimum alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Putrajaya Hospital |
|
Malaysia |
2020-05-18 |
2020-08-31 |
54998, NMRR-20-941-54998 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
|
Dr Thong Kai Shin |
2020-05-19 |
| DPCPM: Disease Progression of COVID-19 Patients in Malaysia |
Coronavirus disease 19 infection |
|
|
|
Government of Malaysia |
|
Malaysia |
2020-05-15 |
2022-04-30 |
54834, DPCPM, NMRR-20-945-54834 |
Phase Not Applicable |
Not yet recruiting |
2 |
23 Months |
|
Devi Peramalah, Dr. Noran Naqiah Hairi |
2020-05-19 |
| COVID-19 in the Swedish ICU-cohort: Risk Factors of Critical Care Admission and Intensive Care Mortality |
Coronavirus disease 19 infection, Diabetes mellitus, Hypertension |
ACE-inhibitors therapy alone, immunosuppressant therapy alone, intensive care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Uppsala University |
Center for Clinical Research Dalarna |
Sweden |
2020-06-30 |
2020-06-30 |
NCT04390074, UTN: U1111-1251-8195 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
10000 |
Björn Ahlström, MD, Miklos Lipcsey, PhD |
2020-05-22 |
| Correlates between knowledge of COVID 19 and practice among patients in Luyang primary health clinic |
Coronavirus disease 19 infection |
|
|
|
KLINIK KESIHATAN LUYANG |
|
Malaysia |
2020-05-15 |
2020-06-15 |
54915, NMRR-20-947-54915 |
Phase Not Applicable |
Not yet recruiting |
1 |
1 Month |
|
Dr Nurul Akmanidar binti Zainuddin, Dr. Lee Wai Khew |
2020-05-19 |
| The Impact and Coping Strategy of COVID-19 Among Taiwan Society and Medical and Nursing Institutes |
Coronavirus disease 19 infection |
coping protocol plan alone, standardized crisis management alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kaohsiung Kai-Suan Psychiatric Hospital |
|
Taiwan |
2020-06-01 |
2023-07-31 |
KSPH-2020-03, NCT04389476 |
Phase Not Applicable |
Not yet recruiting |
1 |
38 Months |
2500 |
Frank Huang-Chih Chou |
2020-05-19 |
| PROTECT: Prophylaxis for patients at risk of COVID-19 infection |
Coronavirus disease 19 infection |
hydroxychloroquine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cambridge University Hospitals NHS Foundation Trust |
University of Cambridge |
UK |
2020-05-31 |
2025-08-31 |
A095590, NCT04389359, PROTECT |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
63 Months |
1500 |
Kerrie Brusby, PhD, Thomas Hiemstra, PhD |
2020-05-18 |
| SEIR models to determine the effectiveness of the Movement Control Order (MCO) during the COVID-19 pandemic in Malaysia |
Coronavirus disease 19 infection |
movement control order (MCO) alone |
|
|
Institute For Medical Research (Inc In Malaysia) |
|
Malaysia |
2020-05-22 |
2020-12-31 |
54856, NMRR-20-953-54856 |
Phase Not Applicable |
Status not specified |
1 |
7 Months |
|
Dr Sarbhan Singh a/l Lakha Singh, Pharmacist Law Kian Boon |
2020-05-20 |
| Safety and Efficacy of Intravenous Wharton's Jelly Derived Mesenchymal Stem Cells in Acute Respiratory Distress Syndrome Due to COVID 19 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
ventilation support therapy alone, Variable regimens including Wharton's jelly derived mesenchymal stem cells , azithromycin , hydroxychloroquine , lopinavir + ritonavir |
HIV protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
BioXcellerator |
Clinical Somer |
Colombia |
2020-06-30 |
2021-05-31 |
BIOXSOMCOV001, NCT04390152 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
11 Months |
40 |
Alfredo Hernandez-Ruiz, MSc, Santiago Saldarriaga-Gomez, MSc |
2020-05-20 |
| Phase II/III, randomized, blinded, placebo-controlled, multicenter trial of emetine in high-risk, symptomatic adult COVID-19 patients not requiring hospitalization |
Coronavirus disease 19 infection |
emetine alone |
|
|
Acer Therapeutics Inc |
|
|
2020-09-30 |
|
|
Phase 2/Phase 3 Clinical |
Planned |
0 |
|
|
|
2020-05-19 |
| To observe the effect of Ayurvedic medicine for the treatment of COVID-19 |
Coronavirus disease 19 infection |
AYUSH 64 alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Central Council for Research in Ayurvedic Sciences |
|
India |
2020-05-24 |
|
CTRI/2020/05/025214 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
|
Dr Sumit Shrivastva |
2020-05-18 |
| Ayurveda formulation for COVID-19 prevention |
Coronavirus disease 19 infection |
Guduchi ghan vati alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Central Council for Research in Ayurvedic Sciences |
|
India |
2020-05-23 |
|
CTRI/2020/05/025213 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1500 |
Dr Kavita Vyas |
2020-05-19 |
| Immunogenetics Predictors With COVID-19 |
Coronavirus disease 19 infection |
genotyping alone, real-time polymerase chain reaction alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Mansoura University |
|
Egypt |
2020-05-10 |
2022-05-09 |
NCT04390269, R.20.05.830.R1 |
Phase Not Applicable |
Not yet recruiting |
1 |
24 Months |
200 |
Mahmoud El-Bendary, M.D |
2020-05-20 |
| Combination: Combination Therapy With Isotretinoin and Tamoxifen May Provide Complete Protection Against Severe Acute Respiratory Syndrome Coronavirus |
Coronavirus disease 19 infection, Respiratory failure |
Variable regimens including isotretinoin , isotretinoin (aerosolized) , tamoxifen |
Estrogen receptor antagonist, Retinoic acid receptor agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Kafrelsheikh University |
|
Egypt |
2020-05-31 |
2020-08-31 |
COV-19 TREATMENT THIS IS, Combination, NCT04389580 |
Phase 2 Clinical |
Not yet recruiting |
1 |
3 Months |
160 |
M.Sc.Mahmoud Elkazzaz, M.Sc.Biochemistry, Mahmoud Ramadan mohamed Elkazzaz |
2020-05-20 |
| PCHF-COVICAV: The Global PCHF-COVICAV Registry |
Acute coronary syndrome, Arterial hypertension, Cardiac arrest, Cardiac failure, Cardiovascular disease, Coronavirus disease 19 infection, Diabetes mellitus, Heart arrhythmia, Lipid metabolism disorder, Myocarditis |
echocardiography alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Zurich |
Wroclaw Medical University |
Switzerland |
2020-04-30 |
2021-07-31 |
NCT04390555, PCHF-COVICAV, PCHF-COVICAV |
Phase Not Applicable |
Recruiting |
1 |
15 Months |
1500 |
Andreas Flammer, PD Dr. med, Frank Ruschitzka, Prof. Dr. med, Mateusz Sokolski, MD, PhD, Sander Trenson, MD |
2020-05-18 |
| The Safety and Preliminary Efficacy of Lucinactant in Adults With COVID-19 |
Acute lung injury, Coronavirus disease 19 infection |
lucinactant (liquid instillate), Windtree Therapeutics/ Esteve/ Lee's Pharmaceutical alone |
Bone morphogenetic protein-10 ligand inhibitor, Bone morphogenetic protein-15 ligand inhibitor, Lung surfactant associated protein B stimulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Windtree Therapeutics Inc |
|
US |
2020-06-01 |
2020-11-30 |
02-CL-2001A, NCT04389671 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
2 |
6 Months |
30 |
Phillip D Simmons, MS, Steven G Simonson, MD, Steven Keller, MD, PhD, Yuh-Chin T Huang, MD, MHS |
2020-05-18 |
| Convalescent Plasma for the Treatment of COVID-19 |
Coronavirus disease 19 infection, Multiple organ failure, Respiratory failure, Septic shock |
ABO compatible COVID-19 convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Thomas Jefferson University |
|
US |
2020-04-15 |
2021-04-14 |
20D.379, NCT04389710 |
Phase 2 Clinical |
Recruiting |
1 |
12 Months |
100 |
Anna Marie Chang, MD, Michael Baram, MD |
2020-05-18 |
| PAP-COVID: Early CPAP in COVID-19 Confirmed or Suspected Patients |
Coronavirus disease 19 infection, Respiratory disease, Viral pneumonia |
WatchPAT alone, continuous positive airway pressure therapy alone, pulse oximeter monitoring alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Mount Sinai School of Medicine |
Community Surgical Supply of Toms River, Inc, Itamar Medical (Cm) 1997 Ltd, Philips Healthcare USA |
US |
2020-05-07 |
2021-05-31 |
GCO 20-0900, NCT04390191, PAP-COVID |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
200 |
Neomi Shah, MD, MPH, MS, Samira Khan, MPH |
2020-05-20 |
| Feasibility of Non-contact Magnetically-controlled Capsule Endoscopy During COVID-19 Pandemic |
Coronavirus disease 19 infection |
MCE system, Ankon Technologies alone, non-contact magnetically-controlled capsule endoscopy alone, simethicone alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Changhai Hospital |
|
China |
2020-03-26 |
2020-05-20 |
NC-MCE PILOTRCT, NCT04389333 |
Phase 2 Clinical |
Recruiting |
1 |
1 Month |
40 |
Jiahui Zhu, MD, Zhuan Liao, Zhuan Liao, MD |
2020-05-18 |
| A study to evaluate the effect of Oral Niclosamide in mild and very mild COVID-19 cases |
Coronavirus disease 19 infection |
niclosamide alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Lady Hardinge Medical College |
|
India |
2020-05-15 |
|
CTRI/2020/04/024949 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
48 |
Anupam Prakash |
2020-05-18 |
| CSTC-Exo: COVID-19 Specific T Cell Derived Exosomes |
Coronavirus disease 19 infection, Viral pneumonia |
COVID-19 specific T cell derived exosomes alone, metered dose inhaler therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
TC Erciyes University |
|
Turkey |
2020-05-01 |
2021-05-31 |
CSTC-Exo, ERUCOVID2020, NCT04389385 |
Phase 1/Phase 2 Clinical |
No longer recruiting |
1 |
13 Months |
60 |
Mustafa Cetin, Prof |
2020-05-20 |
| Ayurveda protocol and COVID-19 exposed individuals: Clinical trial of an Ayurveda Intervention |
Coronavirus disease 19 infection |
Ayurveda management protocol alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
All India Institute of Ayurveda |
|
|
2020-05-16 |
|
CTRI/2020/05/025171 |
Phase 2 Clinical |
Not yet recruiting |
0 |
|
50000 |
Dr Mahesh Vyas, Dr VG Huddar, Prof Dr Tanuja Nesari |
2020-05-19 |
| TACTIC-R: Multi-arm, Therapeutic Study In Pre-ICU Patients Admitted With COVID-19 - Repurposed Drugs |
Coronavirus disease 19 infection |
baricitinib alone, ravulizumab alone, standard of care alone |
Complement C5 factor inhibitor, IgG receptor FcRn large subunit p51 modulator, Jak1 tyrosine kinase inhibitor, Jak2 tyrosine kinase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cambridge University Hospitals NHS Foundation Trust |
Alexion Pharmaceuticals Inc, Eli Lilly & Co Ltd |
UK |
2020-05-01 |
2022-05-01 |
2020-001354-22, CCTU0303, IRAS 282213, ISRCTN11188345, NCT04390464, TACTIC-R, TACTIC-R |
Phase 4 Clinical |
Recruiting |
3 |
24 Months |
1167 |
Dr Joseph Cheriyan, Elena Hernan Sanch0, Elena Hernan-Sancho, Frances Hall Hall, FRCP (UK), D.Phil, Maria King |
2020-05-19 |
| Evaluation of the effect of Tocilizumab on outcomes of the severe COVID-19 patients |
Coronavirus disease 19 infection |
tocilizumab alone |
|
|
Arak University of Medical Sciences and Health Services |
|
Iran |
2020-05-21 |
|
IR.ARAKMU.REC.1399.030, IRCT20200510047383N1 |
Phase 3 Clinical |
Recruiting |
1 |
|
100 |
Dr. Mohammadreza Bozorgmanesh, Zahrasadat Mousavi, ِDr. Mohammadreza Bozorgmanesh |
2020-05-21 |
| A clinical Trial to Study the Effects of Hydroxychloroquine, Ciclesonide and Ivermectin in treatment of moderate COVID-19 illness |
Coronavirus disease 19 infection |
ciclesonide alone, hydroxychloroquine alone, ivermectin alone |
Chloride channel modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Lady Hardinge Medical College |
|
India |
2020-05-15 |
|
CTRI/2020/04/024948 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
120 |
Anupam Prakash |
2020-05-19 |
| Evaluation of Efficacy and Safety of Thymoquinone compared to Best supportive care in Patients with COVID-19 |
Coronavirus disease 19 infection |
Best supportive care alone, Thymoquinone alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Intas Pharmaceuticals Ltd |
|
India |
2020-05-17 |
|
0248-20, Version No: 2.0, CTRI/2020/05/025167 |
Phase 2 Clinical |
Recruiting |
2 |
|
64 |
Dr Dhaiwat Shukla, Dr Janak Khambhoja, Dr Naman Shah, Mr Prashant Modi |
2020-05-19 |
| Study of ASHWAGANDHA TABLET on healthy individuals to prevent covid-19 |
Coronavirus disease 19 infection |
Ashwagandha tablet alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Ministry of Ayush |
|
India |
2020-05-19 |
|
CTRI/2020/05/025166 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
1200 |
Dr C Muralikrishna |
2020-05-19 |
| Patient Outcome of Cardiac Surgery During the COVID-19 Pandemic |
Coronavirus disease 19 infection, Surgical procedure |
cardiac surgery alone, thoracic surgery alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
CHU De Nantes |
|
France |
2020-05-11 |
2022-06-30 |
HEART-19 STUDY, NCT04389463 |
Phase Not Applicable |
Recruiting |
1 |
25 Months |
350 |
Annick COULON, Mickael VOURC'H, MD |
2020-05-19 |
| Use of Desferal for Prevention of ARDS in Hospitalized Cases Documented With Covid 19 Infection |
Coronavirus disease 19 infection, Respiratory distress syndrome |
deferoxamine mesylate alone |
|
|
Cairo University |
|
Egypt |
2020-06-01 |
2020-12-31 |
0012, NCT04389801 |
Phase 4 Clinical |
Not yet recruiting |
1 |
7 Months |
200 |
Hesham Al-Inany |
2020-05-19 |
| CLEO-CD: COVID-19 Related Lockdown Effects On Chronic Diseases |
Age related macular degeneration, Cardiac failure, Coronary artery disease, Coronavirus disease 19 infection, Hematological neoplasm, Hemophilia, Idiopathic pulmonary fibrosis, Macular edema, Multiple sclerosis, Myocardial infarction, Pulmonary artery hypertension, Respiratory failure, Temporal arteritis |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire Dijon |
|
France |
2020-04-20 |
2021-11-07 |
BOULIN AOIC 2020, CLEO-CD, NCT04390126 |
Phase Not Applicable |
No longer recruiting |
1 |
18 Months |
1200 |
|
2020-05-20 |
| Convalescent Plasma for COVID-19 Close Contacts |
Coronavirus disease 19 infection |
convalescent plasma alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Columbia University |
|
US |
2020-05-31 |
2021-04-30 |
AAAT0052, NCT04390503 |
Phase 2 Clinical |
Recruiting |
1 |
11 Months |
200 |
Jennifer Zech, MSc, Jessica Justman, MD |
2020-05-20 |
| Epidemiological, clinical and prognosticated features of novel coronavirus pneumonia (COVID-19) in Zhuhai |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fifth Affiliated Hospital, Sun Yat-Sen University |
|
China |
2020-04-01 |
2021-04-01 |
ChiCTR2000032895 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
100 |
Jing Liu |
2020-05-19 |
| D-dimer Levels in Pregnant With COVID-19 |
Coronavirus disease 19 infection |
ELISA test alone |
|
Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Istanbul Bakirkoy Maternity and Children Diseases Hospital |
|
Turkey |
2020-05-14 |
2020-07-03 |
MTALMAC, NCT04389554 |
Phase Not Applicable |
Recruiting |
1 |
1 Month |
400 |
Merve Aldikactioglu Talmac |
2020-05-19 |
| Interferon Gamma Induced Protein 10 (IP-10) in a Clinical Decision Support Protocol in COVID-19 Patients |
Coronavirus disease 19 infection |
clinical decision support protocol alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
MeMed Diagnostics Ltd |
|
Israel |
2020-04-07 |
2020-05-12 |
MM-5000-BV, NCT04389645 |
Phase Not Applicable |
Completed |
1 |
1 Month |
52 |
Shaul Lev, MD |
2020-05-19 |
| The duration and influencing factors of medical staff wearing disposable protective equipment in the isolation area during novel coronavirus pneumonia (COVID-19): an epidemiological study |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
The First Affiliated Hospital of Dalian Medical University |
|
China |
2020-03-16 |
2020-04-01 |
ChiCTR2000032884 |
Phase Not Applicable |
No longer recruiting |
1 |
|
176 |
Li Fanglin, Shi Tieying |
2020-05-18 |
| Double-Blind, Multicenter, Study to Evaluate the Efficacy of PLX-PAD for the Treatment of COVID-19 |
Adult respiratory distress syndrome, Coronavirus disease 19 infection |
PLX stem cell therapy, Pluristem/Cha Bio & Diostech alone |
IL-6 receptor agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Pluristem Ltd |
|
Israel, US |
2020-05-31 |
2021-09-30 |
NCT04389450, PLX-COV-01 |
Phase 2 Clinical |
Not yet recruiting |
2 |
16 Months |
140 |
Ami Mayo, MD, Paul Sanders, MD |
2020-05-19 |
| International survey to investigate the implementation of ICU daily care for COVID-19 |
Coronavirus disease 19 infection |
|
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Japanese Society of Intensive Care Medicine |
|
North America, Australia, Europe, South America, Asia, Japan, Africa |
2020-05-18 |
|
UMIN000040405 |
Phase Not Applicable |
Not yet recruiting |
2 |
|
200 |
Keibun Liu, Tomoko Nakayasu |
2020-05-19 |
| Novel coronavirus pneumonia (COVID-19) s-vax loaded autologous dendritic cell trial |
Coronavirus disease 19 infection |
autologous dendritic cell vaccine (injection, COVID-19), Beijing TIL Therapeutics alone |
COVID19 Spike glycoprotein modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Beijing TIL Therapeutics Co Ltd |
|
China |
2020-05-01 |
2022-04-30 |
ChiCTR2000033003 |
Phase 0 Clinical |
Not yet recruiting |
1 |
24 Months |
25 |
Xiaoyu Xiang |
2020-05-22 |
| HSS Covid-19 Antibody Serology Among Surgeons and Anesthesiologists |
Coronavirus disease 19 infection |
SARS-CoV2 serum antibody test alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital for Special Surgery NY |
|
US |
2020-05-05 |
2020-10-30 |
2020-0850, NCT04389294 |
Phase Not Applicable |
Recruiting |
1 |
5 Months |
300 |
Alexander P Hughes, MD, Ellen M Soffin, MD, PhD |
2020-05-19 |
| Efficacy evaluation of inhalation therapy (nasal spray) of Interferon Beta-1a in Mild to Moderate cases of Covid-19 at Baqiyatallal Hospital |
Coronavirus disease 19 infection |
national corona treatment alone, hydroxychloroquine plus interferon beta 1a |
|
|
CinnaGen Co |
|
Iran |
2020-05-21 |
|
IR.BMSU.REC.1399.122, IRCT20200511047396N1 |
Phase 3 Clinical |
Recruiting |
1 |
|
100 |
Ashraf Karbasi |
2020-05-21 |
| The effect of cognitive-behavioral intervention on improving COVID-19 fear symptoms, improving quality of life and improving mental health in patients with corona |
Coronavirus disease 19 infection, Psychiatric disorder |
cognitive-behavioral crisis intervention alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Tehran University of Medical Sciences |
|
Iran |
2020-05-03 |
|
IR.TUMS.VCR.REC.1399.335, IRCT20200509047360N1 |
Phase Not Applicable |
Recruiting |
1 |
|
60 |
Seyyed Salman Alavi |
2020-05-20 |
| Evaluation of the effect of GCSF injection in treatment of COVID-19 patients with lymphopenia |
Coronavirus disease 19 infection, Lymphocytopenia, Viral pneumonia |
Granulocyte colony-stimulating factor (GCSF) alone |
|
|
Semnan University of Medical Sciences |
|
Iran |
2020-05-21 |
|
IR.SEMUMS.REC.1399. 13, IRCT20200502047268N1 |
Phase 1/Phase 2 Clinical |
Recruiting |
1 |
|
10 |
Akram Alizadeh, Amir Sarabi, Amir sarabi |
2020-05-21 |
| Evaluation of the efficiency and safety of favipiravir + hydroxychloroquine drug regimen in comparison with hydroxychloroquine in hospitalized patients with covid-19 |
Coronavirus disease 19 infection |
antibiotic therapy alone, Variable regimens including favipiravir , hydroxychloroquine , oxygen |
RNA polymerase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shaheed Beheshti Medical University |
|
Iran |
2020-05-19 |
|
IR.SBMU.RETECH.REC.1399.053, IRCT20200428047228N1 |
Phase 3 Clinical |
Recruiting |
1 |
|
50 |
Dr. Mohammad Fathi, ِDr.Mohammad Fathi |
2020-05-20 |
| A clinical study of imatinib for the treatment in patients with COVID-19-associated ARDS |
Adult respiratory distress syndrome, Coronavirus disease 19 infection |
imatinib alone |
Abl tyrosine kinase inhibitor, Bcr protein inhibitor, Kit tyrosine kinase inhibitor, PDGF receptor antagonist, Signal transduction inhibitor |
|
Exvastat Ltd |
Innovative Medicines Initiative |
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
110 |
|
2020-05-18 |
| Study to Evaluate the Effect of a Probiotic in COVID-19 |
Coronavirus disease 19 infection |
probiotic alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Bioithas SL |
|
Spain |
2020-05-04 |
2021-05-31 |
COVID.PROB, NCT04390477 |
Phase Not Applicable |
Recruiting |
2 |
12 Months |
40 |
Laura Navarro, Maria Isabel Perez-Soto, Maykel Ayo-González, Vicente Navarro |
2020-05-19 |
| A COVID-19 antibody case study to help guide health preservation protocols and public discourse about the pandemic |
Coronavirus disease 19 infection |
|
|
|
Progressive Care Inc |
|
US |
|
|
|
Phase Not Applicable |
Planned |
1 |
|
|
|
2020-05-18 |
| Famotidine Outpatient COVID-19 Treatment Study |
Coronavirus disease 19 infection |
famotidine alone |
Histamine H2 receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Northwell Health Inc |
Cold Spring Harbor Laboratory |
US |
2020-05-12 |
2020-05-20 |
1605914-1, NCT04389567 |
Phase Not Applicable |
No longer recruiting |
1 |
|
10 |
David A Tuveson, MD PhD |
2020-05-19 |
| Antimalarial and COVID-19 in Rheumatoid Arthritis |
Coronavirus disease 19 infection, Rheumatoid arthritis |
hydroxychloroquine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Assiut University |
|
Egypt |
2020-03-15 |
2020-05-01 |
COVID 19 IN RA, NCT04389320 |
Phase Not Applicable |
Completed |
1 |
1 Month |
60 |
Manal Hassanien |
2020-05-19 |
| CONDITION: Contagiousness and Immunogenicity Status of COVID-19 in Asymptomatic Population (COVID-19 CONDITION) |
Coronavirus disease 19 infection |
ELISA test alone, polymerase chain reaction (PCR) test alone |
|
Healthy volunteers accepted |
Igenomix Spain |
|
Spain |
2020-05-07 |
2020-08-31 |
CONDITION, IGX1-COV-XS-20-01, NCT04389658 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
1000 |
Carlos Gomez, BSc MSc, Carlos Gomez, Bsc, MSc, Carlos Simon, MD PhD, Carlos Simon, MD,PhD, Nasser Al-Asmar, BSc PhD, Xavier Santamaria, MD PhD, Xavier Santamaria, MD, PhD, Xavier Santamaria, MD,PhD |
2020-05-19 |
| COPICADS: COVID-19 Pandemic Impact on Patients With Cancer - a Danish Survey |
Cancer, Coronavirus disease 19 infection |
cancer treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Odense University Hospital |
|
Denmark |
2020-05-14 |
2023-05-01 |
COPICADS, NCT04389996, OP_1132 |
Phase Not Applicable |
Recruiting |
2 |
35 Months |
5000 |
Stefan S Jeppesen, MD, PhD, Stefan Starup Jeppesen |
2020-05-20 |
| Dociparstat for the Treatment of Severe COVID-19 in Adults at High Risk of Respiratory Failure |
Acute lung injury, Coronavirus disease 19 infection, Respiratory failure |
dociparstat (iv, AML/acute lung injury/COVID-19), Chimerix alone |
CXCR4 chemokine modulator, Cathepsin G inhibitor, Complement cascade inhibitor, Elastase inhibitor, Heparin agonist, High mobility group protein B1 inhibitor, L selectin antagonist, P selectin antagonist, Platelet factor 4 ligand inhibitor, Stromal cell-derived factor 1 ligand modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Chimerix Inc |
|
US |
2020-05-31 |
2021-03-31 |
CMX-DS-004, NCT04389840 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
10 Months |
524 |
Elizabeth MacLeod, Marion Morrison, MD |
2020-05-20 |
| COVIDICA: Clinical and Psycho-social Impact of COVID-19 Related Confinement on Patients With Digestive Tumors |
Coronavirus disease 19 infection, Gastrointestinal tumor, Metastatic colorectal cancer, Metastatic pancreas cancer |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire De Poitiers Etablissement D’Hospitalisation |
|
France |
2020-05-15 |
2021-05-15 |
2020-A01301-38, COVIDICA, NCT04389684 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
120 |
Violaine RANDRIAN, PhD |
2020-05-19 |
| COSMO: The COVID-19 Symptom Montelukast Trial |
Coronavirus disease 19 infection, Respiratory distress syndrome |
montelukast sodium alone |
Leukotriene D4 antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
McGill University |
Lady Davis Institute |
Canada |
2020-07-31 |
2021-06-30 |
443807, COSMO, NCT04389411 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
11 Months |
600 |
Geoffrey Tranmer, PhD, Machelle Wilchesky, Machelle Wilchesky, PhD |
2020-05-19 |
| COVID-LAN: Lanadelumab for treatment of COVID-19 disease |
Coronavirus disease 19 infection |
lanadelumab alone |
Plasma kallikrein inhibitor |
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Radboud University Medical Center Nijmegen |
|
Netherlands |
|
|
2020-002472-12, COVID-LAN, UMCN-AKF20.04 |
Phase 4 Clinical |
Recruiting |
1 |
|
80 |
Roger Bruggemann |
2020-05-18 |
| Convalescent Plasma as Treatment for Acute Coronavirus Disease (COVID-19) |
Coronavirus disease 19 infection |
SARS-CoV-2 convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Karolinska University Hospital |
Danderyd Hospital, Karolinska Institutet |
Sweden |
2020-04-10 |
2020-12-31 |
CP1, NCT04390178 |
Phase 1/Phase 2 Clinical |
No longer recruiting |
2 |
8 Months |
10 |
Johan Ursing, MD, PhD |
2020-05-19 |
| CoBRA: CoViD-19 imaging register study Aachen |
Coronavirus disease 19 infection |
CoViD-19 imaging alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital, Aachen |
|
Germany |
2020-04-05 |
|
097/20, CoBRA, DRKS00021740 |
Phase Not Applicable |
Recruiting |
1 |
|
100 |
Christiane Kuhl |
2020-05-20 |
| ILIAD 7: Recombinant InterLeukin-7 (CYT-107) to Improve clinical outcomes in lymphopenic pAtients with COVID-19 infection |
Coronavirus disease 19 infection |
CYT-107 alone |
IL-7 receptor agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
RevImmune SAS France |
|
Spain, Italy, US, France, Belgium |
2020-05-06 |
|
2020-001786-36, ILIAD 7, ILIAD-7-UK-Cohort |
Phase 2 Clinical |
Recruiting |
5 |
|
|
Michel Morre |
2020-05-19 |
| Clinical Effects of Internet Assisted Pulmonary Rehabilitation of COVID-2019 Pneumonia Patients After Discharge |
Coronavirus disease 19 infection, Viral pneumonia |
pulmonary rehabilitation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
China-Japan Friendship Hospital |
Ai You Foundation, Wuhan Central Hospital, Wuhan Tuberculosis Prevetion And Cure Hosptial, Wuhan University |
China |
2020-04-06 |
2020-10-30 |
2020-22-K17, NCT04368793 |
Phase Not Applicable |
Recruiting |
3 |
6 Months |
300 |
Geyi Wen, Resident, Guangyun Guo, Doctor, Hongtao Niu, Ting Yang, Doctor, Yi Hu, Doctor, Zhenshun Cheng, Doctor |
2020-05-19 |
| Malaysian COVID-19 Anosmia Study (Phase I) - A Nation-wide, Multicenter, Cross-Sectional Study |
Coronavirus disease 19 infection, Dysomia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sultanah Bahiyah Hospital |
HOSPITAL RAJA PEREMPUAN ZAINAB II, Hospital Enche' Besar Hajjah Khalsom, Hospital Kuala Lumpur, Hospital Permai, Hospital Queen Elizabeth, Hospital Raja Permaisuri Bainun, Hospital Sultan Ismail, Hospital Sultanah Maliha, Hospital Sungai Buloh, Hospital Tengku Ampuan Afzan, Hospital Tuanku Fauziah, Melaka Hospital, Pulau Pinang Hospital, Sarawak General Hospital, Sultanah Aminah Hospital, Sultanah Nur Zahirah Hospital, Tuanku Jaafar Hospital |
Malaysia |
2020-05-31 |
2020-08-31 |
MCO-001, MCO-002 54803, NCT04390165, NMRR-20-934-54803 |
Phase 1 Clinical |
Not yet recruiting |
18 |
3 Months |
760 |
Amran Mohamad, MD MS, Anilawati Mat Jelani, MD MMed, Chee Loon Leong, MBBS MMed, Chenthilnathan Periasamy, MBBS MMed, Chun Yiing Wong, MBBS MMed, Dzawani Muhamad, MD MMed, Elang Kumaran Krishnan, MBBS MS, Fadzilah Ismail, MD MS, Halimuddin Sawali, MBBS MS, Heng Gee Lee, MBChB MRCP, Ibtisam Ismail, BSc, Ida Sadja'ah Sachlin, MBBS MMed, Jeyasakthy Saniasiaya, MMed FEBORL, Jothi Shanmuganathan, MBBS MMed, Kuldip Kaur Prem Kaur, MBBS MPH, Lee Lee Low, MD MRCP, Linda Pei Fang Lim, MD MS, Mahiran Mustafa, MBBCh MMed, Masliza Zaid, MBBS MMed, Mohd Noor Ismail, MD MRCP, Mohd Zambri Ibrahim, MD MMed, Nor Zaila Zaidan, MD MMed, Norzi Gazali, MBBS MMed, Philip Rajan Devesahayam, MMed FRCS, Rosdi Ramli, MBBS MMed, Shahrul Aiman Soelar, B Ind Stats, Sharifah Baizura Syed Alwi, MD MRCPI, Shen-Han Lee, MB PhD MRCS, Siti Sabzah Hashim, MD MS, Siti Sabzah Mohd Hashim, MD MS, Siti Sabzah bt Mohd Hashim, MD, MS, Sobani Din, MD MS, Suhaila Abd Wahab, MBBS MMed, Suhaimi Yusof, MBBS MMed, Suhaimi Yusuf, MBBS MMed, Tengku Mohamed Izam Tengku Kamalden, MS FRCS, Tiang Koi Ng, MBBS MRCP, Ting Soo Chow, MD MRCP, Zhi Xiang Yeoh, MBBS MS MRCS, Zulkiflee Salahuddin, MD MS |
2020-05-21 |
| A clinical trial of OraPro-COVID-19 for the treatment of COVID-19 infection |
Coronavirus disease 19 infection |
OraPro-COVID-19 alone |
COVID19 Spike glycoprotein modulator |
|
Stabilitech Ltd |
|
UK |
2020-06-30 |
|
|
Phase Not Applicable |
Planned |
1 |
|
|
|
2020-05-21 |
| A pilot clinical trial of AntiCovir for the prevention of COVID-19 infection |
Coronavirus disease 19 infection |
interferon alpha-2b (COVID-19, inhaled), Altum Pharmaceuticals alone |
Interferon alpha ligand modulator |
|
Altum Pharmaceuticals Inc, BLife Therapeutics Inc |
|
US |
2020-12-31 |
|
|
Phase Not Applicable |
Planned |
1 |
|
|
|
2020-05-18 |
| NO-COVID-19: Inhaled Nitric Oxide for Preventing Progression in COVID-19 |
Coronavirus disease 19 infection |
nitric oxide (inhaled, INOpulse), Bellerophon alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tufts Medical Center |
Bellerophon Therapeutics LLC |
US |
2020-05-12 |
2021-07-31 |
NCT04388683, NO-COVID-19, STUDY00000554 |
Phase 2 Clinical |
Recruiting |
1 |
14 Months |
42 |
Marvin Konstam, MD, Nicholas Hill, MD |
2020-05-19 |
| A pilot, phase II, randomized, double-blind, placebo controlled trial of interferon alpha-2b for the treatment of COVID-19 infection |
Coronavirus disease 19 infection |
interferon alpha-2b (COVID-19, inhaled), Altum Pharmaceuticals alone |
Interferon alpha ligand modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Altum Pharmaceuticals Inc |
|
Australia |
2020-07-31 |
|
ALT-003-COV-01 |
Phase 3 Clinical |
Planned |
1 |
|
306 |
|
2020-05-18 |
| COVID-19 Treatment of Severe Acute Respiratory Syndrome With Veru-111 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
VERU-111 alone |
Tubulin alpha inhibitor, Tubulin beta inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Veru Inc |
|
US |
2020-05-25 |
2020-08-30 |
NCT04388826, V0211901 |
Phase 2 Clinical |
Not yet recruiting |
5 |
3 Months |
40 |
Domingo Rodriguez, Gary Barnette, Jennifer Stanford, Jenny Koops, Jenny.J.Koops@HealthPartners.Com, Karen Lewandowski |
2020-05-22 |
| COVIDOR: Epidemiological Study of the Covid-19 Presto Test |
Coronavirus disease 19 infection |
Covid-19 presto test alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Orléans Métropole Service de Médecine Préventive |
Universite Francois Rabelais de Tours |
France |
2020-06-18 |
2022-01-18 |
2020-A01414-35, COVIDOR, NCT04387968 |
Phase Not Applicable |
Not yet recruiting |
1 |
19 Months |
700 |
Loic CLECH, MD, Mélanie MONSION, IDEST, Pr Raphaël O SERREAU, MD-PhD, Raphael Serreau, Raphaël SERREAU, MD, PhD |
2020-05-18 |
| SEROSARSCOV: Study of the SARS-COV-2 (COVID-19) Serological Profile of an Army Training Hospital Staff |
Coronavirus disease 19 infection |
ELISA alone, EVOLIS analyzer (Biorad) alone, blood sampling alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Direction Centrale du Service de Sante des Armees |
|
France |
2020-05-13 |
2020-06-24 |
2020-COVID19-10, NCT04387838, SEROSARSCOV |
Phase Not Applicable |
Not yet recruiting |
2 |
1 Month |
900 |
David TRAN-VAN, MD, Elodie VALERO, PharmD, Frédéric JANVIER, MD |
2020-05-18 |
| Post COVID-19 Cardiopulmonary and Immunological Changes (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
Mansoura University |
|
Egypt |
2020-05-11 |
2021-10-10 |
20.05.67, NCT04388436 |
Phase Not Applicable |
No longer recruiting |
1 |
17 Months |
100 |
Tamer A Elhadidy, MD |
2020-05-20 |
| PRAISE@COVID: Screening Patients for a Strategic Shift to Pulmonary Telerehabilitation Because of COVID-19 |
Coronavirus disease 19 infection, Respiratory disease |
pulmonary telerehabilitation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universidade de Lisboa |
Fundacao para a Ciencia e a Tecnologia, Hospital de Santa Maria, Nippon Gases Portugal, Unipessoal, Lda. |
Portugal |
2020-03-20 |
2020-03-27 |
046I/17, NCT04388579, PRAISE@COVID |
Phase Not Applicable |
Completed |
3 |
|
100 |
Catarina D Santos, MSc, Cristina Bárbara, PhD |
2020-05-18 |
| Protecting Health Care Workers During the COVID-19 Outbreak |
Coronavirus disease 19 infection |
ayurvedic kadha intake alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Aarogyam UK |
Samta Ayurveda Prakoshtha |
India |
2020-03-01 |
2020-04-02 |
AU/SA/01, NCT04387643 |
Phase Not Applicable |
Completed |
1 |
1 Month |
52 |
Jaydeep Joshi, Neha Sharma, Parashar Sharma, Sahil Singhal |
2020-05-18 |
| Evaluation of colchicine in treatment of coronavirus |
Coronavirus disease 19 infection |
chloroquine plus colchicine |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Ardabil University of Medical Sciences |
|
Iran |
2020-05-04 |
|
IR.ARUMS.REC.1399.050, IRCT20200418047126N1 |
Phase 3 Clinical |
Recruiting |
1 |
|
100 |
Farhad Pourfarzi, Farhad Salehzadeh, Haleh Valizadeh Haghi, Shahram Habibzadeh |
2020-05-18 |
| CLOT: COVID-19, Blood Coagulation and Thrombosis |
Coronavirus disease 19 infection, Deep vein thrombosis, Lung embolism, Respiratory failure, Viral pneumonia |
CT scan alone, echo-Doppler ultrasound alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ramsay Générale de Santé |
Hôpital Privé Jacques Cartier, service réanimation Dr Bougouin |
France |
2020-05-01 |
2020-09-01 |
2020-A00, CLOT, NCT04388657 |
Phase Not Applicable |
Recruiting |
3 |
4 Months |
100 |
DRE Ramsay santé, Guillaume Peri, Dr, JEAN F OUDET, Julien Nahum, Dr, MH barba, Wulfran Bougouin |
2020-05-18 |
| Favipiravir versus Hydroxychloroquine in COVID-19 |
Coronavirus disease 19 infection |
Plaquenil alone, antiviral treatment alone, favipiravir alone, supportive care alone |
RNA polymerase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Royal College of Surgeons in Ireland - Medical University of Bahrain |
Bahrain Defence Force Royal Medical Services, Military Hospital, Ebrahim Khalil Kanoo Community Medical Center |
Bahrain |
2020-05-14 |
2020-08-14 |
40 / 07-MAY-2020, NCT04387760 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
3 Months |
150 |
Abdulkarim Abdulrahman, Dr., Manaf Al Qahtani, Dr., Mohamed Wael, Dr., Omar Yaghi, Dr., Pearl Wasif, MSc., Salman Yousif Alali, Dr., Sameer Otoom, Prof., Sawsan Saeed, MDPH, Stephen Atkin, Prof. |
2020-05-18 |
| Serologic Surveillance for SARS-CoV-2 (COVID-19) in a Prospective, Cohort of Health Care Workers |
Coronavirus disease 19 infection |
quantitative indirect chemiluminescence immunoassay alone, serological testing alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Italiano de Buenos Aires |
Roche Pharma (Schweiz) AG |
Argentina |
2020-05-15 |
2020-08-31 |
5566, NCT04387890 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
50 |
Cristina Elizondo, MD, Diego Sanchez Thomas, MD, Ines Staneloni, MD, Leticia Peroni, MD, Vanina Stanek, MD |
2020-05-20 |
| Stem cell treatment for COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
human umbilical cord Wharton’s jelly mesenchymal stem cells alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
DEY Company |
|
Iran |
2020-05-12 |
|
IR.SBMU.RETECH.REC.1399.031, IRCT20200421047150N1 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
|
90 |
Ali Asghar Rezaei, Mehran Lak, Mohamad Fathi |
2020-05-19 |
| ACROVID: Analysis of Chilblains profile During COVID-19 Epidemic |
Coronavirus disease 19 infection, Frostbite |
anal swabbing alone, biological sampling alone, blood test alone, skin biopsy alone |
|
Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire De Poitiers Etablissement D’Hospitalisation |
|
|
2020-05-31 |
2021-06-30 |
ACROVID, ACROVID, NCT04387955 |
Phase Not Applicable |
Not yet recruiting |
0 |
13 Months |
30 |
Damien BOUTIN |
2020-05-18 |
| A clinical trial of allogeneic iNKT cell-based immunotherapy for the treatment of COVID-19 infection |
Coronavirus disease 19 infection |
agenT-797 alone |
|
|
AgenTus Therapeutics Inc |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-05-20 |
| Interferon Lambda Therapy for COVID-19 |
Coronavirus disease 19 infection |
peginterferon lambda-1a, Eiger BioPharmaceuticals alone |
Interferon receptor modulator, Interleukin-29 ligand |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Mount Sinai Medical Center |
Eiger BioPharmaceuticals Inc |
US |
2020-04-30 |
2021-05-31 |
GCO 20-0820, NCT04388709 |
Phase 2 Clinical |
Recruiting |
2 |
13 Months |
66 |
Lynn Bui, Thomas Marron, MD |
2020-05-19 |
| QUALICOVID: Care in Patients Hospitalized for Anorexia Nervosa at the Time of the Coronavirus-19 Epidemic |
Anorexia nervosa, Coronavirus disease 19 infection |
intensive outpatient care alone, teleconsultation interview alone, telephone hotline alone, telephone interview alone |
|
Healthy volunteers accepted |
Centre Psychothérapique de Nancy |
|
France |
2020-05-14 |
2020-06-08 |
NCT04387708, QUALICOVID, RIPH 2020-01 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
18 |
Marilou Lamourette, MD, Tatiana Dabrowski |
2020-05-18 |
| DACOVID: Dornase Alfa Administered to Patients With COVID-19 |
Coronavirus disease 19 infection |
albuterol plus dornase alfa |
Deoxyribonuclease I stimulator, Deoxyribonuclease stimulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Feinstein Institute for Medical Research |
Cold Spring Harbor Laboratory |
US |
2020-03-31 |
2020-07-31 |
216, DACOVID, NCT04387786 |
Phase Not Applicable |
No longer recruiting |
1 |
4 Months |
5 |
Betsy J Barnes |
2020-05-19 |
| EPCOvid-1: Safety and Efficacy of Convalescent Plasma Transfusion for Patients With COVID-19 |
Coronavirus disease 19 infection |
convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Instituto Nacional de Ciencias Medicas y Nutricion |
Hospital General Dr. Manuel Gea González, Hospital Regional de Alta Especialidad del Bajio, Hospital San Jose Tec de Monterrey, Instituto Nacional De Cancerologia, Instituto Nacional de Cardiologia Ignacio Chavez, Instituto Nacional de Enfermedades Respiratorias |
Mexico |
2020-06-01 |
2020-12-31 |
3380, EPCOvid-1, NCT04388410 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
7 Months |
250 |
Juan G. Sierra Madero |
2020-05-18 |
| Influence of COVID-19 Infection on sensory organs in othorynolaryngology |
Coronavirus disease 19 infection |
ENT medical examination alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Klinikum der Albert-Ludwigs Universitaet Freiburg |
|
Germany |
2020-05-20 |
|
270/20, DRKS00021664, U1111-1250-9799 |
Phase 0 Clinical |
Not yet recruiting |
1 |
|
100 |
Kathrin Potkowski |
2020-05-18 |
| Investigating the efficacy and safety of Interferon Beta1a nasal spray in controlling the symptoms of patients with COVID-19 |
Coronavirus disease 19 infection |
interferon beta 1a nasal spray alone, routine treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Bagheiat-allah University of Medical Sciences, CinnaGen Co |
|
Iran |
2020-05-14 |
|
IR.BMSU.REC.1399.122, IRCT20080901001165N53 |
Phase 3 Clinical |
Recruiting |
1 |
|
100 |
Mostafa Ghanei, Parisa Kianpour, Seyed Hasan Saadat, Yunes Panahi |
2020-05-19 |
| NCCAPS: NCI COVID-19 in Cancer Patients |
Coronavirus disease 19 infection, Hematological neoplasm, Solid tumor |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Cancer Institute |
|
US |
2020-05-17 |
2023-05-31 |
NCCAPS, NCI-2020-02986, NCICOVID, NCT04387656 |
Phase Not Applicable |
Not yet recruiting |
1 |
36 Months |
2000 |
Larissa A Korde |
2020-05-15 |
| ASPIRE: Assessing the Safety of Pregnancy In the Coronavirus (COVID-19) Pandemic |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of California San Francisco |
|
US |
2020-04-21 |
2022-09-30 |
20-30559, ASPIRE, NCT04388605 |
Phase Not Applicable |
Recruiting |
1 |
29 Months |
11000 |
Eleni Jaswa, MD, MSc, Heather Huddleston, Heather Huddleston, MD |
2020-05-16 |
| Investigating Anosmia and Ageusia in COVID-19 Adult Patients in Saudi Arabia |
Ageusia, Coronavirus disease 19 infection, Dysomia |
NHANES smell and taste tests alone |
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Princess Nourah Bint Abdulrahman University |
|
Saudi Arabia |
2020-06-01 |
2020-12-31 |
20-0189, H-01-R-059, NCT04388618 |
Phase Not Applicable |
Not yet recruiting |
2 |
7 Months |
250 |
AHMAD AALIBRAHIM, M.D, Abdulaziz s Algarni, MD, KHALED SOLIMAN, M.D, Khaled R Suliman, M.D, MARZOOQA ALENIZI, M.D, OSAMA KENTAB, M.D, Osama Y Kentab, M.D, Osama Y Kentab, MD |
2020-05-22 |
| DORM: A randomized, open-label prophylaxis trial among migrant workers at high-risk of Covid-19 |
Coronavirus disease 19 infection |
Variable regimens including hydroxychloroquine , ivermectin , povidone-iodine , vitamin C , zinc |
Chloride channel modulator |
|
National University Hospital (Singapore) Pte Ltd |
|
Singapore |
|
|
2020/00561, DORM |
Phase 3 Clinical |
Status not specified |
1 |
|
|
Dr Raymond Seet Chee Seong |
2020-05-18 |
| Immunological efficacy of Jinhua Qinggan Granule for COVID-19 |
Coronavirus disease 19 infection |
Jinhua qinggan granules alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Tokyo Takanawa Hospital |
|
Japan |
2020-05-15 |
|
UMIN000040407 |
Phase Not Applicable |
No longer recruiting |
1 |
|
15 |
Tomoka Ebisui, Tsutomu Nakamura |
2020-05-19 |
| Detection of Anti-COVID-19 Antibody Levels in an Hospital Population |
Coronavirus disease 19 infection |
RT-PCR alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Istituto Clinico Humanitas |
|
Italy |
2020-05-04 |
2021-05-30 |
1374 IGG COVID-19 HUMANITAS, NCT04387929 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
6000 |
Patrizia Meroni, MD |
2020-05-18 |
| Survey of Satisfaction on Traditional Chinese Medicine Jing-Guan-Fang (JGF) for COVID-19 Prevention |
Coronavirus disease 19 infection |
Jing-Guan-Fang alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Taipei City Hospital |
National Yang Ming University |
Taiwan |
2020-02-20 |
2020-05-30 |
NCT04388644, TCHIRB-10904015-E |
Phase Not Applicable |
Recruiting |
3 |
3 Months |
300 |
Chung Hua Hsu, PhD, Chung-HUa Hsu, PhD, Chung-Hua Hsu, MD, PhD, WEN-YING SUNG, MD, Master |
2020-05-18 |
| 2019nCoV_ICU: Epidemiological and Clinical Characteristics of Critically Ill Patients With COVID-19 |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Policlinico Hospital |
|
Italy |
2020-02-22 |
2020-08-31 |
2019nCoV_ICU, NCT04388670, POLICLINICOH |
Phase Not Applicable |
Recruiting |
2 |
6 Months |
1500 |
Giacomo Grasselli, Associate Professor, Giacomo Grasselli, MD |
2020-05-18 |
| A feasibility study of remote rehabilitation using a wearable biological monitoring device in the patients with COVID-19 |
Coronavirus disease 19 infection |
remote rehabilitation alone, wearable biological monitoring device alone |
|
|
Tokyo Medical and Dental University |
|
Japan |
2020-05-15 |
|
UMIN000040401 |
Phase Not Applicable |
Recruiting |
1 |
|
100 |
Tomoyuki Umemoto |
2020-05-18 |
| PRESCO: Predictors of Severe COVID-19 Outcomes |
Coronavirus disease 19 infection, Respiratory distress syndrome |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Verily Life Sciences LLC |
|
US |
2020-05-31 |
2021-03-31 |
102293, NCT04388813, PRESCO |
Phase Not Applicable |
Not yet recruiting |
1 |
10 Months |
1500 |
|
2020-05-18 |
| COVID-19 Convalescent Plasma for Mechanically Ventilated Population |
Coronavirus disease 19 infection, Viral pneumonia |
convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Pennsylvania |
|
US |
2020-04-30 |
2020-09-30 |
842996 (PENNCCP-01), NCT04388527 |
Phase 1 Clinical |
Recruiting |
1 |
5 Months |
50 |
Julie Starr, Katharine J. Bar, MD |
2020-05-18 |
| Detection Rate of SARS-CoV-2 in Male Genitourinary System and Its Impact on Male Reproductive Health(COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Healthy volunteers accepted, Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Tongji Hospital |
|
China |
2020-05-10 |
2021-05-01 |
2020-S073, NCT04388631 |
Phase Not Applicable |
Recruiting |
1 |
11 Months |
200 |
Jihong Liu, Jihong Liu, M.D, Tao Wang, M.D |
2020-05-19 |
| NPC-19: Negative-PCR for Covid- 19 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Catholic University of the Sacred Heart |
|
Italy |
2020-05-13 |
2020-07-10 |
20200505, NCT04387799, NPC-19 |
Phase Not Applicable |
Recruiting |
1 |
1 Month |
260 |
Anna Caprodossi, Antonio Gasbarrini, MD, Geltrude Mingrone, MD, Giovanni Addolorato, MD, Maria F Russo, MD |
2020-05-18 |
| PROTECT: Preventative treatment for patients at risk of COVID-19 infection |
Coronavirus disease 19 infection |
hydroxychloroquine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cambridge University Hospitals NHS Foundation Trust, University of Cambridge |
April Trust |
UK |
2020-04-03 |
2025-05-03 |
2020-002016-48, CCTU0307, IRAS282317, ISRCTN88057279, PROTECT |
Phase 2/Phase 3 Clinical |
Recruiting |
37 |
61 Months |
500 |
Dr Hiemstra, Kerry Brusby |
2020-05-22 |
| A phase I trial to evaluate mRNA vaccine (LPP delivery platform, COVID-19), Shanghai Yinuosi Biotechnology/Tongji University/Biocad/Stemrina Therapeutics for the prevention of SARS-CoV-2 infection |
Coronavirus disease 19 infection |
mRNA vaccine (LPP delivery platform, COVID-19), Shanghai Yinuosi Biotechnology/Tongji University/Biocad/Stemrina Therapeutics alone |
|
|
Biocad Ltd |
|
Russian Federation |
2020-10-31 |
|
|
Phase 1 Clinical |
Planned |
1 |
|
|
|
2020-05-15 |
| Radiographic findings and their temporal changes in COVID-19 positive patient: A Prospective study |
Coronavirus disease 19 infection |
reverse transcriptase polymerase chain reaction test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Max Super Speciality Hospital |
|
India |
2020-05-06 |
|
CTRI/2020/05/025041 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
200 |
Dr Bharat Kumar, Dr Saroj Kumar sabath, Rajesh Saxena |
2020-05-18 |
| Use of High Flow Nasal Cannula Oxygen and COVID-19 Acute Hypoxemic Respiratory Failure |
Coronavirus disease 19 infection, Hypoxia, Respiratory failure, Viral pneumonia |
nasal high flow cannula oxygen therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hôpital Louis Mourier |
|
France |
2020-03-01 |
2020-05-04 |
HLM_JDR9, NCT04385823 |
Phase Not Applicable |
Completed |
1 |
2 Months |
62 |
Jean-Damien Ricard, MD, PhD, Prof Jean-Damien RICARD |
2020-05-18 |
| Photobiomodulation Therapy Combined With Static Magnetic Field in Patients With COVID-19 |
Coronavirus disease 19 infection, Respiratory failure |
MR5 Activ Pro LaserShower (Multi Radiance Medical) alone, photobiomodulation therapy alone, standard physical therapy alone, static magnetic field therapy alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universidade Nove de Julho |
Hospital Tacchini/RS |
Brazil |
2020-05-18 |
2020-07-31 |
3.985.226, NCT04386694 |
Phase Not Applicable |
Recruiting |
2 |
2 Months |
30 |
Ernesto Cesar Leal Junior, PhD, Ernesto Cesar Pinto Leal Junior, Fabiano Francio, Thiago De Marchi, PhD |
2020-05-21 |
| Oral 25-hydroxyvitamin D3 and COVID-19 |
Coronavirus disease 19 infection |
25-hydroxyvitamin D3 alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Tehran University of Medical Sciences |
Boston University |
Iran |
2020-04-14 |
2021-03-15 |
IR.TUMS.VCR.REC.1399.061, IRCT2020-0401046909N2, IRCT20200401046909N1, NCT04386850 |
Phase 3 Clinical |
Recruiting |
5 |
11 Months |
1500 |
Arash shirvani, Mohamadali Sahraian, MD, Zhila Maghbooli, PhD, zhila Maghbooli, PhD, zhila maghbooli, PhD |
2020-05-21 |
| Study of the Safety of Therapeutic Treatment With an Immunomodulary Agent (N-803 in Adults With COVID-19) |
Coronavirus disease 19 infection |
N-803 alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
ImmunityBio Inc |
|
|
2020-05-11 |
2020-07-11 |
NCT04385849, QUILT-COVID-19 |
Phase 1b Clinical |
Not yet recruiting |
0 |
2 Months |
30 |
Jeff Safrit |
2020-05-18 |
| Vitamin D and COVID-19 Management |
Coronavirus disease 19 infection, Vitamin D deficiency |
ergocalciferol alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Alberta |
|
Canada |
2020-05-31 |
2020-12-31 |
00100606, NCT04385940 |
Phase 3 Clinical |
Not yet recruiting |
1 |
7 Months |
64 |
Aldo Montano-Loza |
2020-05-14 |
| Taiwan 'Aerosol Box' Versus UMMC 'Intubation Box' |
Coronavirus disease 19 infection |
Aerosol Box alone, Intubation Box alone |
|
Healthy volunteers accepted |
University of Malaya |
|
Malaysia |
2020-05-15 |
2020-12-30 |
2020410-8498, NCT04385576 |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
30 |
Dr SHAIRIL RAHAYU BINTI RUSLAN, INA I SHARIFFUDDIN, MAnaes, MOHD F ZAINAL ABIDIN, MAnaes, SHAIRIL R RUSLAN, MAnaes(UM) |
2020-05-14 |
| Neonatal Complications of Coronavirus Disease (COVID-19) |
Coronavirus disease 19 infection |
|
|
Newborn Infants (up to 5 months) |
University of Oxford |
Imperial College London, Public Health England, St Georges University of London, University Hospital of Wales, University of Glasgow, University of Leicester, University of Nottingham |
UK |
2020-04-01 |
2021-09-30 |
14905, NCT04386109 |
Phase Not Applicable |
Recruiting |
1 |
18 Months |
500 |
Dr C Gale, MBBS,MSc,PhD, Professor J Kurinczuk, MBChB,MSc,MD |
2020-05-15 |
| SALICOV: Detection of COVID-19 in Saliva Collection |
Coronavirus disease 19 infection |
saliva sampling alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire D Amiens |
|
France |
2020-05-11 |
2020-08-31 |
NCT04386551, PI2020_843_0045, SALICOV |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
225 |
Catherine François, MD, Etienne Brochot, MD, Jean-Luc Schmit, Pr, Jean-Philippe Lanoix, MD, Sandrine Castelain, Pr, Yves Edouard Herpe, Ing |
2020-05-15 |
| A Phase III, Double-blind, Randomized, Placebo-controlled, Multicenter Clinical Trial to Assess the Efficacy and Safety of VPM-1002 in Reducing Healthcare Professionals' Absenteeism in the SARS-CoV-2 Pandemic by Modulating the Immune System |
Coronavirus disease 19 infection, Respiratory disease |
VPM-1002 alone |
Listeriolysin stimulator |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Vakzine Projekt Management GmbH |
FGK Clinical Research GmbH |
Germany |
2020-05-18 |
2021-06-30 |
NCT04387409, VPM1002-DE-3.06COV |
Phase 3 Clinical |
Not yet recruiting |
1 |
13 Months |
1200 |
Leander Grode, Dr rer nat |
2020-05-14 |
| Ayurvedic Interventions in prevention of COVID-19 infection-A survey study |
Coronavirus disease 19 infection |
Ashwagandha plus Sanshamani Vati |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Central Council for Research in Ayurvedic Sciences |
|
India |
2020-05-16 |
|
CTRI/2020/05/025069 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
1324 |
Dr BCS Rao, Dr Babita Yadav |
2020-05-14 |
| COVASTIL: A Study to Evaluate the Safety and Efficacy of MSTT1041A (Astegolimab) or UTTR-1147A in Patients With Severe COVID-19 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
RG-6149 alone, RG-7880 alone |
IL-22 agonist, Interleukin 1 like receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Genentech Inc |
|
US |
2020-05-22 |
2020-10-27 |
COVASTIL, GA42469, NCT04386616 |
Phase 2 Clinical |
Recruiting |
20 |
5 Months |
300 |
Clinical Trials |
2020-05-22 |
| Can a medicine help in curing viral infection |
Coronavirus disease 19 infection |
ivermectin alone |
Chloride channel modulator |
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Christian Medical College, Vellore, India, Science and Engineering Research Board |
|
India |
|
|
CTRI/2020/05/025068 |
Phase 2b Clinical |
Not yet recruiting |
1 |
|
50 |
Biju George |
2020-05-18 |
| Covid-19 and Prevention of Malnutrition After Confinement by Dentists |
Coronavirus disease 19 infection, Malnutrition |
medical consultation alone, nutritional supplement intake alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire De Nice |
|
France |
2020-05-11 |
2021-05-11 |
20ODONTOCOVID-02, NCT04386460 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
100 |
Isabelle precheur, Isabelle precheur, PUPH, isabelle precheur, valerie Pouyssegur, PH |
2020-05-18 |
| CYCOV-II: Cytokine Adsorption in Patients With Severe COVID-19 Pneumonia Requiring Extracorporeal Membrane Oxygenation |
Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia |
Cytosorb adsorber alone, cytokine adsorption alone, extracorporeal membrane oxygenation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Klinikum der Albert-Ludwigs Universitaet Freiburg |
Kliniken Ludwigsburg-Bietigheim gGmbH, Klinikum Ibbenbüren, Ludwig-Maximilians University of Munich, Martin-Luther-Universitaet, SLK Klinikum Heilbronn GmbH, Saarland University Hospital, Universitat Ulm |
Germany |
2020-06-01 |
2021-10-31 |
CYCOV-II, CYCOV-II, NCT04385771 |
Phase Not Applicable |
Not yet recruiting |
1 |
17 Months |
80 |
Alexander Supady, Dr., MPH |
2020-05-15 |
| A clinical trial to investigate the anti-inflammatory properties of cannabidiol in COVID-19 patients with cardiac injury |
Coronavirus disease 19 infection, Heart injury |
cannabidiol alone |
|
|
Cardiol Therapeutics Inc |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
|
|
2020-05-14 |
| Phase II Clinical Trial Evaluating FUJIFILM Toyama Chemical’s Favipiravir as a Preventative Measure Against COVID-19 in Canadian Long-Term Care Facilities |
Coronavirus disease 19 infection |
favipiravir alone |
RNA polymerase inhibitor |
|
Appili Therapeutics Inc |
|
Canada |
|
|
|
Phase 2 Clinical |
Planned |
1 |
|
|
|
2020-05-15 |
| A clinical trial of Ad5-nCoV for the prevention/treatment of COVID-19 infection |
Coronavirus disease 19 infection |
Ad5-nCoV alone |
COVID19 Spike glycoprotein modulator |
|
CanSino Biologics Inc, Canadian Center for Vaccinology, Canadian Immunization Research Network, National Research Council of Canada |
|
Canada |
|
|
|
Phase Not Applicable |
Not yet recruiting |
1 |
|
|
|
2020-05-22 |
| CONNECTDEM: Cognitive Outcomes During COVID-19 confinement in Elderly and Their Caregivers Using Technologies for Dementia |
Acute stress disorder, Coronavirus disease 19 infection, Dementia, Depression, Mild cognitive impairment |
telephone interview alone |
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fundacion Publica Andaluza para la Investigacion de Malaga en Biomedicina y Salud |
Consorci Sanitari de Terrassa |
Spain |
2020-05-04 |
2020-06-30 |
CONNECT DEM, CONNECTDEM, NCT04385797 |
Phase Not Applicable |
Not yet recruiting |
2 |
1 Month |
414 |
Fermín Mayoral-Cleries, Fermín Mayoral-Cleries, MD, PhD, Jessica M Goodman-Casanova, RNCS, Maite Garolera, PhD, María Quintana, PhD |
2020-05-15 |
| Compassionate Use of Hyperbaric Oxygen Therapy |
Coronavirus disease 19 infection |
hyperbaric oxygen therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
SerenaGroup |
The Wound Treatment Center |
US, Poland |
2020-05-11 |
2022-05-11 |
HBOT-COVID-19, NCT04386265 |
Phase Not Applicable |
Recruiting |
11 |
24 Months |
100 |
Thomas E Serena, MD |
2020-05-20 |
| Kidney Injury Severity and COVID-19 |
Coronavirus disease 19 infection, Renal injury, Respiratory distress syndrome, Viral pneumonia |
CT scan alone, urine test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
IM Sechenov Moscow Medical Academy |
|
Russian Federation |
2020-05-15 |
2020-11-15 |
NCT04386564, SECHENOV-COVID19_AKI |
Phase Not Applicable |
Not yet recruiting |
1 |
6 Months |
120 |
Dmitry Enikeev, M.D., Ph.D., Dmitry Enikeev, MD, Mark Taratkin, M.D. |
2020-05-14 |
| A randomized, double-blinded, parallel-controlled clinical trial for azvudine in the treatment of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Standard of Care alone, azvudine alone |
Nucleoside reverse transcriptase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Beijing Ditan Hospital Capital Medical Universty |
|
China |
2020-05-12 |
|
ChiCTR2000032769 |
Phase 2 Clinical |
Recruiting |
6 |
|
342 |
Wan Yuanhao, Zhang Fujie |
2020-05-14 |
| Trial of Alpha-1 Antitrypsin Inhalation in Treating Patient With Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) |
Coronavirus disease 19 infection |
alpha-1 antitrypsin (iv, alpha-1 antitrypsin deficiency/type 1 diabetes/GvHD/ lung transplant rejection), Kamada/Shire alone |
Alpha 1 antitrypsin stimulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ministry of Health Saudi Arabia |
|
Saudi Arabia |
2020-06-01 |
2020-09-01 |
4-0520- 076-K-02-H, NCT04385836 |
Phase 0 Clinical |
Recruiting |
1 |
3 Months |
150 |
mohammed m othman, mtair |
2020-05-21 |
| Evaluation of the use of hydroxychlorochine in Chinese flu |
Coronavirus disease 19 infection |
proper COVID19 treatment alone, azithromycin plus hydroxychloroquine |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital da Criança Santo Antônio |
|
Brazil |
2020-05-01 |
|
Número do CAAE: 30585020.2.0000.0008, Número do Parecer do CEP: 3.982.682, RBR-3k4wxb, U1111-1250-7492 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
45 |
Marcos Aurelio Barboza de Oliveira |
2020-05-21 |
| The Philippine CORONA: Neurological Manifestations of COVID-19 (CORONA) |
Coronavirus disease 19 infection, Neurological disease |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of the Philippines |
Asian Hospital and Medical Center, Baguio General Hospital and Medical Center, Cagayan Valley Medical Center, Capitol Medical Center, Cardinal Santos Medical Center, Chong Hua Hospital, De La Salle University Medical Center, Dr. Pablo O. Torre Memorial Hospital, East Avenue Medical Center, Jose B. Lingad Memorial Regional Hospital, Jose R. Reyes Memorial Medical Center, Lung Center of the Philippines, Makati Medical Center, Manila Doctors Hospital, Medical Center Manila, New Era General Hospital, Ospital ng Makati, Philippine Heart Center, Quirino Memorial Medical Center, Research Institute for Tropical Medicine, San Juan De Dios Educational Foundation Inc. - Hospital, San Lazaro Hospital, Southern Isabela Medical Center, Southern Philippines Medical Center, St. Luke's Medical Center, The Medical City, Philippines, University of Santo Tomas Hospital, University of the East Ramon Magsaysay Memorial Medical Center, Inc, Veterans Memorial Medical Center |
Philippines |
2020-05-31 |
2021-03-31 |
NCT04386083, RGAO-2020-0348, The Philippine CORONA |
Phase Not Applicable |
Not yet recruiting |
1 |
10 Months |
1342 |
Adrian I Espiritu, MD, Roland Dominic G Jamora, MD |
2020-05-23 |
| A Clinical Study on Favipiravir Compared to Standard Supportive Care in Patients With Mild to Moderate COVID-19 |
Coronavirus disease 19 infection |
Standard Supportive Care alone, favipiravir alone |
RNA polymerase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Glenmark Pharmaceuticals Ltd |
|
India |
2020-05-20 |
|
CTRI/2020/05/025114, GPL/CT/2020/002/III |
Phase 3 Clinical |
Not yet recruiting |
5 |
|
150 |
Amol Pendse, Dr Abdul Ansari, Dr Atul Jindal, Dr Bharat Purandare, Dr Chandrakant Pawar, Dr Keyur Madan Brahme, Dr Meenakshi Bhattacharya, Dr Pawan Singh, Dr Rajesh Gosavi, Dr Tanu Singhal, Dr Urman Dhruv |
2020-05-19 |
| Study of effect of Yashtimadhu tablet for the prevention of COVID -19 on healthy individuals |
Coronavirus disease 19 infection |
Yashtimadhu alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Ministry of Ayush |
|
India |
2020-05-18 |
|
CTRI/2020/05/025093 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
1200 |
Dr G Babu, Dr Sujata Pundalikrao Dhoke, Dr Sujata pundlikrao Dhoke |
2020-05-15 |
| The effect of zinc on the treatment and clinical course of patients with SARS-cov2 (COVID-19) |
Coronavirus disease 19 infection |
hydroxychloroquine sulfate plus zinc |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Isfahan University of medical Sciences |
|
Iran |
2020-04-20 |
|
IR.MUI.MED.REC.1399.074, IRCT20180425039414N2 |
Phase 2/Phase 3 Clinical |
No longer recruiting |
1 |
|
80 |
Atousa Hakamifard, Ziba Farajzadegan |
2020-05-22 |
| To study the Effectiveness of herbal formulation - Aayudh Advance as a supplementary treatment for the Corona Virus 2019 (Covid-19) infected patients |
Coronavirus disease 19 infection |
Herbal formulation - Aayudh Advanced alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shukla Ashar Impex Pvt. Ltd., Rajkot |
|
India |
2020-05-16 |
|
ARL/CSP/2020/002-01, CTRI/2020/05/025161 |
Phase 2 Clinical |
Recruiting |
1 |
|
120 |
Dr Bhavdeep Ganatra, Dr Jayesh Dutt, Dr Manish Rachchh |
2020-05-18 |
| Pa-COVID-19: Analysis of the Pathophysiology and Pathology of Corona Virus Disease 2019 |
Coronavirus disease 19 infection |
|
|
|
Charité Campus Virchow-Klinikum |
Charite Universitaetsmedizin Berlin |
Germany |
2020-03-01 |
|
DRKS00021688, EA2/066/20, Pa-COVID-19 |
Phase Not Applicable |
Recruiting |
1 |
|
1500 |
Florian Kurth, Leif-Erik Sander |
2020-05-15 |
| COMBAT-COVID-19: Efficacy and safety of 72-h infusion of Prostacyclin (1 ng/kg/min) in patients with COVID-19 induced respiratory failure - a multicenter, randomized, placebo-controlled, blinded, investigator-initiated trial |
Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure |
iloprost (inhaled nebulizer formulation, pulmonary hypertension), Bayer Schering/Actelion alone |
PGI2 agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Copenhagen University Hospital, Hvidovre |
BioPorto Diagnostics A/S, The Danish National Advanced Technology Foundation |
Denmark |
2020-05-06 |
|
2020-001296-33, COMBAT-COVID-19, COMBAT-COVID-19 |
Phase 2 Clinical |
Recruiting |
4 |
|
80 |
Kristine Pedersen |
2020-05-21 |
| POVA-TIE: Measurement of Airway Opening Pressure (AOP) in Patients With Acute Respiratory Distress Syndrome and With or Without Covid 19 |
Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia |
PEEP derived electrical impedance tomography alone, global ventilator pressure volume measurement alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital, Bordeaux |
|
France |
2020-05-20 |
2021-05-20 |
CHUBX 2020/15, NCT04386720, POVA-TIE |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
20 |
Eline BONNARDEL, Dr, Hadrien ROZE, Dr |
2020-05-21 |
| COVID-19 Pandemic and Academic Performance of Veterinary Students |
Coronavirus disease 19 infection |
online survey alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
South Valley University |
|
Egypt |
2020-04-13 |
2020-05-15 |
1-2020, NCT04387214 |
Phase Not Applicable |
Recruiting |
1 |
1 Month |
400 |
Mohamed Mahdy |
2020-05-16 |
| Artificial ventilation setting in patients infected with COVID19 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
Artificial ventilation alone, infusion pumps alone, mechanical ventilator alone, ultiparametric monitor alone, norepinephrine plus vasopressin |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Universitario Pedro Ernesto, Universidade Federal do Rio de Janeiro |
|
Brazil |
2020-04-29 |
|
3,997,807, 31050420.8.1001.5259, A32070754871, RBR-2z3f7k |
Phase Not Applicable |
Recruiting |
1 |
|
30 |
Luciana Moisés Camilo, Monica Rodrigues Cruz, Tiago Batista da Costa Xavier |
2020-05-19 |
| Effect of Ayurveda intervention AYUSH-64 add-on therapy for patients with COVID-19 infection (Stage I) |
Coronavirus disease 19 infection |
AYUSH-64 alone, standard treament alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Central Council for Research in Ayurvedic Sciences |
|
India |
2020-05-18 |
|
CTRI/2020/05/025156 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
60 |
Dr R Govind Reddy, Dr Rajesh Vithal Gosavi |
2020-05-19 |
| HOP-COVID: COVID-19 Infection in Healthcare Workers |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assistance Publique Hopitaux de Paris |
|
France |
2020-05-31 |
2020-10-31 |
APHP200483, HOP-COVID, NCT04386759 |
Phase Not Applicable |
Not yet recruiting |
1 |
5 Months |
6000 |
Sylvie BASTUJI-GARIN, MD, PhD |
2020-05-15 |
| A population-based study was to evaluate the whether androgen-deprivation therapies (ADTs) could protect patients affected by prostate cancer from SARS-CoV-2 infections |
Coronavirus disease 19 infection, Prostate tumor |
androgen-deprivation therapies alone |
|
|
Universita Degli Studi Di Padova |
|
Italy |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
|
Andrea Alimonti |
2020-05-14 |
| Demographics and Outcomes of COVID 19 in Pregnancy at a Community Based Hospital |
Coronavirus disease 19 infection, Pregnancy disorder |
COVID positive testing alone |
|
Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Atlantic Health System |
|
US |
2020-05-31 |
2020-12-31 |
1595116-1, NCT04385914 |
Phase Not Applicable |
Not yet recruiting |
1 |
7 Months |
200 |
Farah Benarba, Samantha Collazo, MD |
2020-05-18 |
| The Impact of COVID-19 on the Health Care Utilization of Inflammatory Bowel Disease |
Coronavirus disease 19 infection, Inflammatory bowel disease |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Keimyung University Dongsan Medical Center |
Yeungnam University College of Medicine |
South Korea |
2020-04-24 |
2021-03-30 |
2020-04-070, NCT04387279 |
Phase Not Applicable |
Recruiting |
3 |
11 Months |
800 |
Kyeong Ok Kim, Ph.D., Yoo Jin Lee, Yoojin Lee, M.D. |
2020-05-17 |
| Placebo-controlled clinical trial to evaluate the efficacy and safety of hydroxychloroquine and azithromycin in relation to placebo in the negative viral load of participants with SARS-CoV2 flu syndrome and who do not have an indication for hospitalization |
Coronavirus disease 19 infection, Viral pneumonia |
azithromycin plus hydroxychloroquine |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Hospital Santa Paula |
|
Brazil |
2020-04-11 |
|
3,964,568, 30413020.8.0000.0008, A 33166752803, RBR-95yjmq |
Phase 3 Clinical |
Recruiting |
1 |
|
108 |
Ana Tarina Alvarez Lopes |
2020-05-17 |
| Phase Ib/II Trial of Dendritic Cell Vaccine to Prevent COVID-19 in Frontline Healthcare Workers and First Responders |
Coronavirus disease 19 infection |
AV-COVID-19 alone, AV-COVID-19 plus GM-CSF |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Aivita Biomedical Inc |
|
|
2020-09-30 |
2021-04-30 |
CL-COV-P01-US, NCT04386252 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
0 |
7 Months |
180 |
Candace Hsieh, PhD, Robert O Dillman, MD |
2020-05-17 |
| OsCOVID19: Phase II RCT to Assess Efficacy of Intravenous Administration of Oxytocin in Patients Affected by COVID-19 |
Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia |
deep vein thrombosis prophylaxis treatment alone, non-invasive ventilation alone, oxygen therapy alone, steroid therapy alone, Variable regimens including azithromycin , darunavir + cobicistat , hydroxychloroquine , lopinavir + ritonavir , oxytocin , remdesivir |
Coronavirus non structural protein 8 modulator, HIV protease inhibitor, RNA polymerase modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Azienda Ospedaliero-Universitaria di Parma |
Universita' Degli Studi Di Parma |
Italy, France |
2020-06-03 |
2020-12-31 |
NCT04386447, OSCOVID19, OsCOVID19 |
Phase 2 Clinical |
Not yet recruiting |
4 |
6 Months |
145 |
Angela Sirigu, PhD, Antonina Carai, MD, Antonio Nouvenne, MD,PhD, Antonio Nouvenne, MD,Phd, Carlo Ferrari, MD,Phd, Caterina Caminiti, PhD, Gianluca Deiana, MD, PhD, Giuseppe Maglietta, PhD, Licia Abbruzzese, MD, Lorenzo Finardi, MD,Phd, Peppino Paffi, MD, Pier Francesco Ferrari, PhD, Riccardo Volpi, MD,PhD, Tiziana Meschi, Tiziana Meschi, MD, PhD, Tiziana Meschi, MD,PhD |
2020-05-20 |
| Evaluating the Efficacy of Artesunate in Adults With Mild Symptoms of COVID-19 |
Coronavirus disease 19 infection |
artemisinin alone, artesunate alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Princess Nourah Bint Abdulrahman University |
|
Saudi Arabia |
2020-06-30 |
2020-12-31 |
20-0192, IN PROCESS, NCT04387240 |
Phase 2 Clinical |
Not yet recruiting |
1 |
6 Months |
22 |
Abdulaziz S Algarni, MD, Osama Kentab, MD, Osama Y Kentab, MD |
2020-05-21 |
| APRV-COVID19: Evaluation of Airway Pressure Release Ventilation in COVID-19 ARDS |
Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia |
Airway pressure release ventilation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Central Hospital, Nancy, France |
|
France |
2020-05-15 |
2020-06-30 |
2020PI076, APRV-COVID19, NCT04386369 |
Phase Not Applicable |
Not yet recruiting |
1 |
1 Month |
40 |
Matthieu Koszutski, MD |
2020-05-17 |
| Study on the Use of Sarilumab in Patients With COVID-19 Infection |
Coronavirus disease 19 infection |
Variable regimens including chloroquine , hydroxychloroquine , sarilumab |
IL-6 receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
ASST Fatebenefratelli Sacco |
|
Italy |
2020-05-31 |
2020-12-31 |
COVID-SARI-001, NCT04386239 |
Phase 0 Clinical |
Not yet recruiting |
1 |
7 Months |
40 |
Agostino Riva, MD, Massimo Galli, Professor, Stefano Rusconi |
2020-05-17 |
| COVIDIMM: Immune Changes in Severe COVID-19 Pulmonary Infections |
Coronavirus disease 19 infection, Hypoxia, Lung infection, Respiratory failure |
NAVIOS flow cytometer (Beckman Coulter) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Central Hospital, Nancy, France |
|
France |
2020-03-30 |
2020-05-30 |
CHRU NANCY : 2020PI080_1, COVIDIMM, NCT04386395 |
Phase Not Applicable |
No longer recruiting |
1 |
2 Months |
15 |
MARIE REINE LOSSER, MD, PhD |
2020-05-17 |
| COVIDANCE: Losartan and spironolactone treatment for COVID-19 patients with acute respiratory failure in intensive care unit |
Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure |
losartan alone, spironolactone alone |
Aldosterone antagonist, Angiotensin II AT-1 receptor antagonist, Angiotensin II receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assistance Publique Hopitaux De Marseille |
|
France |
2020-04-29 |
|
2020-001766-11, 2020-24, COVIDANCE |
Phase 2 Clinical |
Recruiting |
1 |
|
|
clinical project manager |
2020-05-18 |
| GYNE-COVID: Study of Late Fetal Loss in Poitou-Charentes |
Coronavirus disease 19 infection, Spontaneous abortion |
polymerase chain reaction alone |
|
Healthy volunteers accepted |
Centre Hospitalier Universitaire De Poitiers Etablissement D’Hospitalisation |
|
France |
2020-05-20 |
2021-07-20 |
GYNE-COVID, GYNE-COVID, NCT04387253 |
Phase Not Applicable |
Not yet recruiting |
1 |
14 Months |
80 |
|
2020-05-22 |
| Investigating the Role of Vitamin D in the Morbidity of COVID-19 Patients |
Coronavirus disease 19 infection |
vitamin D alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tameside Hospital NHS Foundation Trust |
|
UK |
2020-06-01 |
2021-06-01 |
NCT04386044, TGH1234 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
1000 |
Edward Jude, MD, Margaret Cooper, Rebecca Roberts |
2020-05-18 |
| Hydroxychloroquine prophylaxis in Covid 19 infection |
Coronavirus disease 19 infection, SARS coronavirus infection |
hydroxychloroquine alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Indian Council of Medical Research |
|
India |
2020-05-04 |
|
CTRI/2020/05/025010, HCQ Pro Study Protocol Version 1.3, |
Phase Not Applicable |
Status not specified |
6 |
|
2000 |
Dr Atul gogia, Dr Dorairajan Sureshkumar, Dr Neeraj Agarwal, Dr Suneela Garg, Dr Vikas Bhatia, Madhavi Eerike, Pranab Chatterjee, Prof Pankaja Raghav, Suman Kanungo |
2020-05-15 |
| WHO SOLIDARITY Finland: A clinical study to evaluate the efficacy of different anti-viral drugs in SARS-CoV-2 infected patients (COVID-19) |
Coronavirus disease 19 infection |
hydroxychloroquine sulphate (Oxiklorin ) plus remdesivir |
Coronavirus non structural protein 8 modulator, RNA polymerase modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Clinical Urology and Epidemiology Working Group, University of Helsinki |
|
Finland |
2020-04-29 |
|
2020-001784-88, WHO SOLIDARITY Finland, WHO-FIN-COVID-19 |
Phase 3 Clinical |
Recruiting |
1 |
|
664 |
Dept. of Public Health |
2020-05-18 |
| An observational, retrospective study to evaluate hydroxychloroquine administration in patients with Covid-19 who had been admitted to the hospital |
Coronavirus disease 19 infection |
hydroxychloroquine alone |
|
|
New York State Department Of Health |
|
US |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
1446 |
|
2020-05-14 |
| Evaluation of the effectiveness of rabbit antibody against coronavirus in patients |
Coronavirus disease 19 infection, Viral pneumonia |
COVID-19 treatment alone, CoviGlobulin alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kowsar Biotechnology Co |
|
Iran |
2020-05-21 |
|
IR.BMSU.REC.1399.110, IRCT20200508047346N1 |
Phase 3 Clinical |
Recruiting |
1 |
|
124 |
Dr. Mostafa Ghanei, Mahdi Behdani, Mostafa Ghanei, Sirous Zeinali |
2020-05-21 |
| LymphoCov1: Clinical Epidemiology and Characteristics Of Covid-19 Cases Occurred In A Lymphoma Setting In The First Epidemic Phase |
Coronavirus disease 19 infection, Lymphoma |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Versailles University Hospital |
|
France |
2020-05-15 |
2020-07-15 |
LymphoCov1, NCT04386512, P20/12_LYMPHOCOV |
Phase Not Applicable |
Not yet recruiting |
1 |
2 Months |
50 |
Caroline Besson |
2020-05-18 |
| CATALYST: A randomized, phase II proof of principle multi-arm multi-stage trial designed to guide the selection of interventions for phase III trials in hospitalized patients with COVID-19 infection |
Coronavirus disease 19 infection |
Drug therapy alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The University of Birmingham |
United Kingdom Research & Innovation |
UK |
2020-03-26 |
2021-05-01 |
2020-001684-89, CATALYST, CPMS 45648, IRAS 282431, ISRCTN40580903, RG_20-030 |
Phase 2 Clinical |
Recruiting |
1 |
13 Months |
|
Dr Rowe |
2020-05-18 |
| Outcomes of viral infection in hematology patients |
Coronavirus disease 19 infection, Hematological disease |
|
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Science and Engineering Research Board |
|
India |
2020-05-28 |
|
CTRI/2020/05/025092 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
250 |
Biju George |
2020-05-15 |
| Knowledge status of public about COVID 19 disease prevention and control in Tamil Nadu |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Siddha Central Research Institute |
|
India |
2020-05-20 |
|
CTRI/2020/05/025091 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
125 |
Dr C Anbarasi, Dr R Meena, Dr S Natarajan |
2020-05-15 |
| COVID MILK: COVID MILK |
Coronavirus disease 19 infection |
|
|
|
Emma Childrens Hospital Foundation |
|
Netherlands |
2020-05-01 |
2020-06-30 |
COVID MILK, Trial NL8575 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
60 |
Johannes (Hans) B. van Goudoever |
2020-05-15 |
| COVUSd: COVID19 ultrasound diagnosis |
Coronavirus disease 19 infection |
ultrasound alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Isala |
|
Netherlands |
2020-04-18 |
2020-06-01 |
COVUSd, Trial NL8544 |
Phase Not Applicable |
Recruiting |
1 |
1 Month |
50 |
Svenja Haak |
2020-05-15 |
| CVC for COVID-19: Charite Trial of Cenicriviroc (CVC) Treatment for COVID-19 patients |
Coronavirus disease 19 infection |
cenicriviroc alone, standard of care alone |
CCR2 chemokine antagonist, CCR5 chemokine antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Charite Universitaetsmedizin Berlin |
|
Germany |
2020-05-11 |
|
2020-001493-29, CVC for COVID-19, CVC-for-COVID-19 |
Phase 2 Clinical |
Recruiting |
1 |
|
200 |
Dept. of Hepatology and Gastroenter |
2020-05-15 |
| A randomized-controlled study to investigate the potential efficacy of monalizumab compared to standard of care against COVID-19 in cancer patients with mild symptoms |
Coronavirus disease 19 infection |
monalizumab alone |
NKG2 A B activating NK receptor antagonist |
|
Centre Leon Berard, Innate Pharma SA |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-05-14 |
| A randomized-controlled study to investigate the potential efficacy of avdoralimab compared to standard of care against COVID-19 in cancer patients with pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
avdoralimab (IPH5401) alone |
CXCR1 chemokine antagonist, Complement C5a receptor antagonist, IL-8 receptor antagonist, Monocyte chemotactic protein 1 ligand inhibitor |
|
Centre Leon Berard, Innate Pharma SA |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-05-14 |
| Low Dose Radiotherapy in COVID-19 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
radiotherapy (0.5 Gy) alone, standard treatment alone |
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shaheed Beheshti Medical University |
|
Iran |
2020-05-04 |
2020-12-31 |
23568, IR.SBMU.RETECH.REC.1399.073, IRCT20200509047366N1, NCT04390412 |
Phase 1/Phase 2 Clinical |
Recruiting |
2 |
7 Months |
5 |
Ahmad Ameri, Ahmad Ameri, Prof., Imam Hossein Hospital, Nazanin Rahnama, M.D. |
2020-05-21 |
| MPN-COVID: Myeloproliferative Neoplasms (MPN) and COVID-19 |
Coronavirus disease 19 infection, Myelofibrosis, Polycythemia, Polycythemia vera |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fondazione per la Ricerca Ospedale Maggiore |
European Leukemia Net |
Italy, UK, Spain, Germany, Denmark, France |
2020-05-01 |
2020-09-01 |
FROM - O-MPN-COVID-2020, MPN-COVID, NCT04385160 |
Phase Not Applicable |
Not yet recruiting |
39 |
4 Months |
80 |
Alessandra Carobbio, BioStat, Alessandra Iurlo, Alessandro Maria Vannucchi, Andrea Patriarca, Arianna Masciulli, PharmD, Chiara Paoli, Claire Harrison, Clara De Ambrogi, Daniele Vanni, Denise Soldati, Elena Elli, Elena Rossi, Elisa Rumi, Emilia Florea, Fabrizio Cavalca, Francesca Pirillo, Giulia Benevolo, Giulia Desa, Giuseppe Rossi, Hans Carl Hasselbalch, Ida Martinelli, Ilaria Nichele, Jean-Jacques Kiladjian, Luigi Scaffidi, Marco Ruggeri, Massimiliano Bonifacio, Monia Marchetti, Paola Guglielmelli, Rosa Daffini, Rosalba Sciancalepore, Silvia Artuso, Silvia Betti, Stefania Priolo, Steffen Koschmieder, Valerio De Stefano |
2020-05-14 |
| Evaluating the effect of intravenous hydrocortisone, methylprednisolone, and dexamethasone in treatment of patients with moderate to severe acute respiratory distress syndrome caused by COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
dexamethasone alone, hydrocortisone alone, methylprednisolone alone, routine care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Hamadan University of Medical Sciences |
|
Iran |
2020-06-04 |
|
IR.UMSHA.REC.1399.152, IRCT20120215009014N354 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
81 |
Dr Abbas Taher, Dr. Fariba Keramat, Dr. Jalal Poorolajal, Dr. Saeid Bashirian |
2020-05-15 |
| COSiN: Collection of Coronavirus COVID-19 Outbreak Samples in New South Wales |
Coronavirus disease 19 infection |
blood sampling alone |
|
|
National Centre in HIV Epidemiology and Clinical Research |
|
Australia |
2020-05-06 |
2021-06-30 |
COSiN, NCT04383652, VISP2005 |
Phase Not Applicable |
Recruiting |
9 |
13 Months |
200 |
Adam Bartlett, Angie Pinto, Bernard Hudson, Gail Matthews, Jeffrey Post, Marianne Martiello, Marianne Martinello, Michael Mina, Nicky Gilroy, Rowena Bull, William Rawlinson |
2020-05-14 |
| A global study to evaluate the safety, tolerability and efficacy of the immunoglobulin therapy (COVID-19), CoVIg-19 Plasma Alliance in adult patients with COVID-19 |
Coronavirus disease 19 infection |
anti-SARS-CoV-2 polyclonal hyperimmune immunoglobulin therapy (COVID-19), CoVIg-19 Plasma Alliance/ Takeda/ CSL Behring alone |
|
|
CoVIg-19 Plasma Alliance, National Institute of Allergy and Infectious Diseases |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-05-14 |
| COVIDAge Study: Outcomes in Hospitalized Older Patients With COVID-19 |
Coronavirus disease 19 infection |
|
|
Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hopitaux Universitaires De Geneve |
|
Switzerland |
2020-03-13 |
2020-04-14 |
2020-00819, COVIDAge Study, NCT04385212 |
Phase Not Applicable |
Completed |
1 |
1 Month |
230 |
Christine Serratrice |
2020-05-15 |
| A phase I clinical study of COVID-19 vaccine (measles vaccine vector technology), Institut Pasteur/Themis Bioscience/University of Pittsburgh for the potential prevention of COVID-19 infection |
Coronavirus disease 19 infection |
COVID-19 vaccine (measles vaccine vector technology), Institut Pasteur/Themis Bioscience/University of Pittsburgh alone |
|
|
Themis Bioscience GmbH |
ABL Europe |
|
|
|
|
Phase 1 Clinical |
Planned |
0 |
|
|
|
2020-05-14 |
| MASC- study: Metabolic syndrome And Severity of Covid-19 |
Coronavirus disease 19 infection, Metabolic syndrome X |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sint Franciscus Gasthuis |
|
Netherlands |
2020-04-28 |
2020-06-01 |
2020-041, MASC- study, NL8580 |
Phase Not Applicable |
Recruiting |
1 |
1 Month |
100 |
Cathelijne van Zelst |
2020-05-18 |
| TBA: Lung ultrasound findings in patients with novel SARS CoV2 |
Coronavirus disease 19 infection |
lung ultrasound alone |
|
|
Amsterdam UMC |
|
Netherlands |
2020-03-26 |
2020-04-23 |
FWA00017598, NL8540, TBA |
Phase Not Applicable |
No longer recruiting |
1 |
|
50 |
Mark Haaksma |
2020-05-15 |
| COVID KIDS: Humoral responses to SARS-CoV-2 infection in children |
Coronavirus disease 19 infection |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Emma Children’s Hospital |
|
Netherlands |
2020-04-12 |
2021-04-04 |
COVID KIDS, NL73556.018.20, NL8531 |
Phase Not Applicable |
Recruiting |
1 |
11 Months |
420 |
Dasja Pajkrt |
2020-05-17 |
| Malaysian COVID-19 Anosmia Study (Phase II) - A Nation-wide, Multicenter, Case-Control Study |
Coronavirus disease 19 infection, Dysomia |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sultanah Bahiyah Hospital |
HOSPITAL RAJA PEREMPUAN ZAINAB II, Hospital Enche' Besar Hajjah Khalsom, Hospital Kuala Lumpur, Hospital Permai, Hospital Queen Elizabeth, Hospital Raja Permaisuri Bainun, Hospital Sultan Ismail, Hospital Sultanah Maliha, Hospital Sungai Buloh, Hospital Tengku Ampuan Afzan, Hospital Tuanku Fauziah, Melaka Hospital, Pulau Pinang Hospital, Sarawak General Hospital, Sultanah Aminah Hospital, Sultanah Nur Zahirah Hospital, Tuanku Jaafar Hospital |
Malaysia |
2020-05-31 |
2020-08-31 |
MCO-002, NCT04384042 |
Phase 2 Clinical |
Not yet recruiting |
18 |
3 Months |
60 |
Amran Mohamad, MD MS, Anilawati Mat Jelani, MD MMed, Chee Loon Leong, MBBS MMed, Chenthilnathan Periasamy, MBBS MMed, Chun Yiing Wong, MBBS MMed, Dzawani Muhamad, MD MMed, Elang Kumaran Krishnan, MBBS MS, Fadzilah Ismail, MD MS, Halimuddin Sawali, MBBS MS, Heng Gee Lee, MBChB MRCP, Ibtisam Ismail, BSc, Ida Sadja'ah Sachlin, MBBS MMed, Jeyasakthy Saniasiaya, MMed FEBORL, Jothi Shanmuganathan, MBBS MMed, Kuldip Kaur Prem Kaur, MBBS MPH, Lee Lee Low, MD MRCP, Linda Pei Fang Lim, MD MS, Mahiran Mustafa, MBBCh MMed, Masliza Zaid, MBBS MMed, Mohd Noor Ismail, MD MRCP, Mohd Zambri Ibrahim, MD MMed, Nor Zaila Zaidan, MD MMed, Norzi Gazali, MBBS MMed, Philip Rajan Devesahayam, MMed FRCS, Rosdi Ramli, MBBS MMed, Shahrul Aiman Soelar, B Ind Stats, Sharifah Baizura Syed Alwi, MD MRCPI, Shen-Han Lee, MB PhD MRCS, Siti Sabzah Hashim, MD MS, Siti Sabzah Mohd Hashim, MD MS, Sobani Din, MD MS, Suhaila Abd Wahab, MBBS MMed, Suhaimi Yusof, MBBS MMed, Suhaimi Yusuf, MBBS MMed, Tengku Mohamed Izam Tengku Kamalden, MS FRCS, Tiang Koi Ng, MBBS MRCP, Ting Soo Chow, MD MRCP, Zhi Xiang Yeoh, MBBS MS MRCS, Zulkiflee Salahuddin, MD MS |
2020-05-17 |
| ICOS: International SARS-CoV-2 (COVID-19) Infection Observational Study |
Coronavirus disease 19 infection, Dyspnea |
biological sampling alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Minnesota |
National Institute of Allergy and Infectious Diseases, National Institutes of Health |
Denmark, US, Argentina, UK |
2020-05-15 |
2021-06-30 |
75N91019D00024, ICOS, ICOS, NCT04385251 |
Phase Not Applicable |
Not yet recruiting |
4 |
13 Months |
10000 |
Edward Gardner, Eileen Denning, James Neaton, PhD, Jens Lundgren, Sarah Pett |
2020-05-14 |
| COVIDNA: Pre-exposure Prophylaxis With Hydroxychloroquine in Sanitaries Highly Exposed to COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
hydroxychloroquine alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Fundación Pública Miguel Servet |
Instituto de Salud Carlos III |
Spain |
2020-04-23 |
|
2020-001697-30, COVIDNA, COVIDNA |
Phase 3 Clinical |
No longer recruiting |
1 |
|
200 |
RUTH GARCÍA |
2020-05-14 |
| Lung ultrasound and computed tomography for monitoring SARS-CoV-2 in critical care departments |
Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia |
Lung ultrasound monitoring alone, computed tomography monitoring alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Amsterdam UMC |
|
|
2020-03-27 |
2020-05-10 |
NL8584 |
Phase Not Applicable |
Recruiting |
0 |
1 Month |
80 |
Micah Heldeweg |
2020-05-15 |
| Validation of 3D nasopharyngeal swab |
Coronavirus disease 19 infection |
3D nasopharyngeal swab validation alone |
|
|
Universiti Sains Islam Malaysia |
|
Malaysia |
2020-05-18 |
2020-11-19 |
54849, NMRR-20-879-54849 |
Phase Not Applicable |
Not yet recruiting |
1 |
6 Months |
30 |
Dr Nor Eyzawiah Binti Hassan, Dr SITI ASMAT BINTI MD AREPEN |
2020-05-14 |
| COH-FIT: Collaborative Outcomes Study on Health and Functioning During Infection Times During COVID-19 Pandemic |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Padova |
Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Northwell Health Inc |
Greece |
2020-04-26 |
2022-06-30 |
COH-FIT, COH-FIT, NCT04383470 |
Phase Not Applicable |
Recruiting |
1 |
26 Months |
100000 |
Agorastos Agorastos, Agorastos Agorastos, MD, Andres Estradè, MSc, Christoph U. Correll, MD, Marco Solmi, MD |
2020-05-15 |
| BEAT-COVID1: Biomarker-based Early Anti-inflammatory Therapy for severe COVID-19 |
Coronavirus disease 19 infection, Lung injury, Multiple organ failure |
Anti-inflammatory Therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Leiden University Medical Center |
|
Netherlands |
2020-04-24 |
2020-09-30 |
BEAT-COVID1, METC LDD P20.046, NL8589 |
Phase Not Applicable |
Recruiting |
1 |
5 Months |
250 |
Anna Roukens, Dr. L.G. Visser |
2020-05-18 |
| RISC: Role of Ibuprofen and Other Medicines on Severity of Coronavirus Disease 2019 |
Coronavirus disease 19 infection |
|
|
|
University Hospital, Bordeaux |
Bordeaux PharmacoEpi |
France |
2020-05-11 |
2020-07-31 |
CHUBX 2020/13, NCT04383899, RISC |
Phase Not Applicable |
Not yet recruiting |
9 |
2 Months |
200 |
Alexandre BOYER, Pr, Anne-Marie LEROI, Pr, Denis MALVY, Pr, Didier GRUSON, Pr, Duc NGUYEN, Dr, Florentia KAGUELIDOU, Dr, Jean-Jacques KILADJIAN, Pr, Jean-Luc CRACOWSKI, Pr, Jean-Sébastien HULOT, Pr, Marc BARDOU, Pr, Nicholas MOORE, Pr, Patrick BLIN, Dr, Rachel FROGET, Dr |
2020-05-14 |
| Fear Among Dentists During COVID-19 Pandemic |
Anxiety disorder, Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cairo University |
|
Egypt |
2020-03-02 |
2020-05-05 |
COVID-19 PANDEMIC, NCT04383626 |
Phase Not Applicable |
Completed |
1 |
2 Months |
216 |
|
2020-05-14 |
| 'Investigation of the Relationship Between New Coronary Virus Disease (COVID-19) and Anxiety and Depressive Symptoms in Pregnant Women' |
Anxiety disorder, Coronavirus disease 19 infection, Depression |
|
|
Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Istanbul Bakirkoy Maternity and Children Diseases Hospital |
|
Turkey |
2020-04-25 |
2020-07-26 |
BECKCOVID, NCT04384887 |
Phase Not Applicable |
No longer recruiting |
1 |
3 Months |
100 |
Pınar Yalcin bahat |
2020-05-14 |
| Covid-19 Triage Using Camera-based AI |
Coronavirus disease 19 infection |
RIA-device (Remote Investigation and Assessment) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Vastra Gotaland Region |
Detectivio Ab |
Sweden |
2020-05-31 |
2020-12-31 |
NCT04383457, U1111-1251-4114 |
Phase Not Applicable |
Not yet recruiting |
1 |
7 Months |
500 |
Ronny K Gunnarsson, MD PhD, Stefan Malmberg, MD |
2020-05-14 |
| Efficacy and Tolerability of Hydroxychloroquine in Adult Patients With COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia, Viral respiratory tract infection |
Plaquenil alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Taoyuan General Hospital |
Center For Disease Control Department Of Health Taiwan Roc, Center for Drug Evaluation, Taiwan, National Health Research Institutes, Taiwan Food and Drug Administration |
Taiwan |
2020-04-01 |
2020-09-30 |
NCT04384380, TYGH109014 |
Phase 4 Clinical |
Recruiting |
1 |
6 Months |
45 |
Chien-Yu Cheng, Dr., Jang-bin Chen, Dr., Shu-Hsing Cheng, Dr., YUNG-NIEN HSU, Dean, Yi-Chun Lin, Dr. |
2020-05-14 |
| Surveillance of Individuals Following SARS-CoV-2 Exposure |
Coronavirus disease 19 infection |
antibody assays alone, reverse transcription-polymerase chain reaction (RT-PCR) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Institute of Allergy and Infectious Diseases |
National Institutes of Health Clinical Center |
US |
2020-05-28 |
2023-06-16 |
20-I-0117, 200117, NCT04383444 |
Phase Not Applicable |
Recruiting |
1 |
36 Months |
1050 |
Lisa A Barnhart, R.N., Steven M Holland, M.D. |
2020-05-23 |
| Outcome of COVID-19 Patients After Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome |
Coronavirus disease 19 infection, Respiratory distress syndrome |
extracorporeal membrane oxygenation therapy alone |
|
|
HELSINKI UNIVERSITY HOSPITAL |
|
Italy, Sweden, France, Germany, Finland, UK |
2020-03-01 |
2020-12-31 |
COVID-19 ECMO, NCT04383678 |
Phase Not Applicable |
Recruiting |
11 |
10 Months |
200 |
Andrea Perrotti, Antonio Fiore, Antonio Loforte, Enrico Leo, Fausto Biancari, Fausto Biancari, Professor, Giovanni Mariscalco, Henryk Welp, Lars M Broman, Magnus Dalen, Magnus Dalen, Assoc prof, Magnus Dalén, Nicla Settembre, Svante Zipfel, Vito G Ruggieri |
2020-05-22 |
| A randomized controlled trial of hydroxychloroquine prophylaxis for Healthcare Workers exposed to COVID-19 |
Coronavirus disease 19 infection |
hydroxychloroquine alone, standard care Personal protective equipment alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
George Institute for Global Health India |
|
India |
2020-06-15 |
|
CTRI/2020/05/025067 |
Phase 2 Clinical |
Not yet recruiting |
3 |
|
10990 |
Dr Bala Venkatesh, Dr Bharath Kumar, Professor Vivekanand Jha |
2020-05-15 |
| COVER-PRO: Evaluation of Emergency Department (ED) Staff Stress Level During COVID-19 Pandemic |
Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection |
stress and anxiety questionnaire alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospices Civils De Lyon |
|
France |
2020-04-18 |
2020-08-18 |
69HCL20_0330, COVER-PRO, NCT04383886 |
Phase Not Applicable |
Recruiting |
5 |
4 Months |
200 |
Guillaume DURAND, MD, Julien BERTHILLER, Karim TAZAROURTE, MD, Laurent JACQUIN, MD, Marion DOUPLAT, MD, Vanessa LABEYE, MD |
2020-05-14 |
| GERONIMO 19: Study of the Efficiency of Normal Human Immunoglobulins (Ivig) in Patients Aged 75 Years and over Covid-19 with Severe Acute Respiratory Failure |
Coronavirus disease 19 infection, Respiratory failure |
polyvalent intravenous immunoglobulin alone, tandard management alone |
|
Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Central Hospital, Versailles |
|
France |
2020-04-27 |
|
2020-001768-27, GERONIMO 19, P20/07 |
Phase 2 Clinical |
Recruiting |
1 |
|
|
Mélody FORT |
2020-05-14 |
| Randomized controlled trial of an app-based intervention, Anchored, to support the mental health of Australians recently unemployed due to COVID-19 |
Coronavirus disease 19 infection |
Anchored app alone, mindfulness exercises alone, psychoeducational videos alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Australian Government Department of Health and Ageing |
|
Australia |
2020-06-01 |
2020-12-30 |
ACTRN12620000555954 |
Phase Not Applicable |
Not yet recruiting |
1 |
6 Months |
492 |
Dr Mark Deady |
2020-05-19 |
| RECOVER: A Randomized, Open-label, Phase-II Clinical Trial with or without Infusion of Plasma from Subjects after Convalescence of SARS-CoV-2 Infection in High-Risk Patients with Confirmed Severe SARS-CoV-2 Disease |
Coronavirus disease 19 infection |
convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Heidelberg |
German Federal Ministry of Education and Research |
Germany |
2020-04-05 |
|
2020-001632-10, EudraCT-N° 2020-001632-10, RECOVER, SARS-CoV-2CP-HD-001 |
Phase 2 Clinical |
Recruiting |
1 |
|
174 |
Prof. Dr. Carsten Müller-Tidow |
2020-05-14 |
| COVID-19 Prophylaxis With Hydroxychloroquine Associated With Zinc For High-Risk Healthcare Workers |
Coronavirus disease 19 infection |
hydroxychloroquine plus zinc sulfate |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Nucleo De Pesquisa E Desenvolvimento De Medicamentos Da Universidade Federal Do Ceara |
Federal University of Ceara |
Brazil |
2020-05-31 |
2020-10-31 |
HCQZN, NCT04384458 |
Phase 2 Clinical |
Not yet recruiting |
1 |
5 Months |
400 |
A, Elisabete A Moraes (betemora), Elisabete A Moraes, Professor |
2020-05-14 |
| ALLIANCE: International ALLIANCE Study of Therapies to prevent progression of COVID-19, a randomized trial |
Coronavirus disease 19 infection |
Variable regimens including Vit B12 , Vit D3 , Vitamin C , azithromycin , hydroxychloroquine , zinc |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Rinehart Medical Foundation |
National Institute of Integrative Medicine |
US, Australia |
2020-05-18 |
2021-06-30 |
ACTRN12620000557932p, ALLIANCE |
Phase 2 Clinical |
Not yet recruiting |
3 |
13 Months |
200 |
A/Prof Karin Ried |
2020-05-14 |
| ADAPT: COVID-19 Study - A prospective, observational cohort study at St Vincent’s Hospital Sydney |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
St Vincents Hospital Sydney Ltd |
|
Australia |
2020-05-14 |
2022-05-31 |
ACTRN12620000554965, ADAPT |
Phase Not Applicable |
Not yet recruiting |
1 |
24 Months |
300 |
A/Prof Gail Matthews |
2020-05-14 |
| VICTORIA: VICTORIA |
Coronavirus disease 19 infection, Viral pneumonia |
itolizumab alone |
T-cell differentiation antigen CD6 inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The Center of Molecular Immunology |
|
Cuba |
2020-03-28 |
2020-07-31 |
IIC RD-EC 179, RPCEC00000311, VICTORIA |
Phase 2 Clinical |
Recruiting |
5 |
4 Months |
80 |
Armando Caballero Lopez, Crombet Ramos, Mayra Ramos-Suzarte |
2020-05-18 |
| Evaluation of the safety and efficacy of BIOMODULINA T for the prevention of infections, including COVID-19, in older adults in Cuba. Phase IV clinical trial (COVID-19) |
Coronavirus disease 19 infection |
Biomodulina T alone |
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Biopreparations Center |
|
Cuba |
2020-04-03 |
2020-07-30 |
GEC2020BMT024, RPCEC00000310 |
Phase 4 Clinical |
Recruiting |
1 |
3 Months |
|
Macias Abraham, Reyes Zamora, Rodriguez Rivera |
2020-05-18 |
| Organicell Flow for Patients With COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
Organicell flow alone, standard care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Organicell Regenerative Medicine |
|
US |
2020-05-31 |
2020-12-31 |
19881, NCT04384445 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
2 |
7 Months |
20 |
George C Shapiro, MD, FACC, George Shapiro, MD, Maria Ines Mitrani, MD, PhD, Marie Saylor, RN, MSN, William Kapp, MD, FAAOS |
2020-05-22 |
| Accelerated iTBS for Depressed Patients During the COVID-19 Pandemic |
Coronavirus disease 19 infection, Major depressive disorder, Psychotic disorder |
B70 Fluid-Cooled Coil alone, MagPro X100 stimulator alone, accelerated intermittent theta burst stimulation alone, relapse prevention treatment alone, virtual check-in alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre for Addiction and Mental Health |
|
Canada |
2020-05-01 |
2022-11-01 |
059/2020, NCT04384965 |
Phase Not Applicable |
Recruiting |
1 |
30 Months |
200 |
Daniel Blumberger, MD, Mawahib Semeralul, Nicole Schoer |
2020-05-15 |
| Health and Wellbeing of Pregnant and Post-Partum Women During the COVID-19 Pandemic |
Coronavirus disease 19 infection |
online survey alone |
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Pregistry |
Harvard TH Chan School of Public Health |
US |
2020-05-15 |
2020-08-31 |
0002, NCT04385238 |
Phase Not Applicable |
Recruiting |
2 |
3 Months |
2500 |
Diego Wyszynski, MD, MHS, PhD, Karestan Koenen, PhD, Sonia Hernandez-Diaz, MD, DrPH, Sonia Hernandez-Diaz, MD, DrPh |
2020-05-20 |
| TX-COVID19: TX-COVID19 |
Coronavirus disease 19 infection |
Nebulization alone, Homeostec plus Paracetamol |
|
|
Cancerology State Institute, Colima State Health Services, Universidad de Colima |
|
Mexico |
2020-05-20 |
2021-01-15 |
RPCEC00000309, TX-COVID19 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
7 Months |
50 |
Delgado Enciso, Paz Garcia |
2020-05-18 |
| COV2-CP: Hyperimmune Plasma in Patients With COVID-19 Severe Infection |
Coronavirus disease 19 infection |
plasma hyperimmune therapy alone, standard therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Universita' Degli Studi "Magna Graecia" Di Catanzaro |
Azienda Ospedaliera Bianchi Melacrino Morelli, Azienda Ospedaliera Universitaria Mater Domini di Catanzaro, Azienda Sanitaria Provinciale Di Catanzaro, Hospital of Cosenza |
Italy |
2020-05-01 |
2021-05-15 |
COV2-CP, COVID-19 CONVALESCENT PLASMA, NCT04385043 |
Phase 2/Phase 3 Clinical |
Recruiting |
6 |
12 Months |
400 |
Alfonso Trimarchi, MD, Andrea Dominijanni, MD, Carlo Torti, MD, Federico Longhini, MD, Francesco Zinno, MD, Gabriella Talarico, MD, Giovanni Matera, MD, Luca Gallelli, Lucio Cosco, MD, Maria Laura Guzzo, MD, Paola Grandini, MD, Pasquale Minchella, MD, Patrizia Leonardo, MD, Piero Gangemi, MD |
2020-05-14 |
| ISCA: Inhaled Sedation in COVID-19-related Acute Respiratory Distress Syndrome (ISCA): an International Research Data Study in the Recent Context of Widespread Disease Resulting From the 2019 (SARS-CoV2) Coronavirus Pandemics (COVID-19) |
Coronavirus disease 19 infection, Respiratory distress syndrome |
Inhaled sedation alone, Intravenous sedation alone, isoflurane alone, sevoflurane alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Clermont-Ferrand |
Groupe Hospitalier Pitie-Salpetriere, University of Valencia, Universitätsklinikum Schleswig-Holstein |
Spain, Germany, France |
2020-05-31 |
2020-12-31 |
ISCA, ISCA STUDY, NCT04383730 |
Phase Not Applicable |
Not yet recruiting |
6 |
7 Months |
400 |
Caroline Varillon, Jean-Michel Constantin, Lise Laclautre, Matthieu Jabaudon, Pierre Boucher, Rafael Badenes |
2020-05-14 |
| ACTT 2: A randomized, controlled clinical trial evaluating the safety and efficacy of a remdesivir plus baricitinib for coronavirus disease 2019 (COVID-19) |
Coronavirus disease 19 infection |
baricitinib plus remdesivir |
Coronavirus non structural protein 8 modulator, Jak1 tyrosine kinase inhibitor, Jak2 tyrosine kinase inhibitor, RNA polymerase modulator |
|
National Institutes of Health |
National Institute of Allergy and Infectious Diseases |
US |
2020-05-08 |
|
ACTT 2 |
Phase Not Applicable |
Recruiting |
1 |
|
|
|
2020-05-19 |
| StayHome: Early Hydroxychloroquine to Reduce Secondary Hospitalization and Household Transmission in COVID-19 |
Coronavirus disease 19 infection |
hydroxychloroquine alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Lausanne |
|
Switzerland |
2020-05-12 |
2020-10-31 |
NCT04385264, StayHome, UNISANTE |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
5 Months |
800 |
Alix Miauton, MD, Blaise Genton, MD-PhD, Jacques Cornuz, MD-PhD, Mary-Anne Hartley, MD, PhD MPH, Mary-Anne Hartley, MD, PhD, MPH, Valérie D'Acremont, MD-PhD |
2020-05-15 |
| Covid-19 Pandemic: Patients Experience in T1D |
Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression, Diabetic ketoacidosis, Hypoglycemia, Insulin dependent diabetes |
|
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
McGill University |
Canadian Institutes of Health Research, Juvenile Diabetes Research Foundation |
Canada |
2020-04-29 |
2021-01-01 |
2021-1079, NCT04384471 |
Phase Not Applicable |
Recruiting |
1 |
8 Months |
384 |
Anne-Sophie Brazeau, PhD |
2020-05-15 |
| Familles-COVID: Psychological Impact of the Hospitalization of a Family Member in Intensive Care for Covid-19 Infection |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hopitaux Universitaires de Strasbourg |
|
France |
2020-05-31 |
2021-02-28 |
7761, Familles-COVID, NCT04385121 |
Phase Not Applicable |
Not yet recruiting |
1 |
9 Months |
60 |
Ferhat MEZIANI, Julie HELMS |
2020-05-14 |
| Safety and Immunogenicity Study of Inactivated Vaccine for Prevention of SARS-CoV-2 Infection (COVID-19) |
Coronavirus disease 19 infection |
Inactivated vaccine (COVID-19), Sinovac Biotech alone |
|
Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sinovac Research & Development Co Ltd |
|
China |
2020-05-20 |
2020-07-20 |
NCT04383574, PRO-NCOV-1002 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
2 Months |
422 |
Hui Jin, Yuliang Zhao, Master |
2020-05-18 |
| Rapid Detection 2019-nCOV via Surface Plasamon Resonance |
Coronavirus disease 19 infection |
RT-PCR method alone, Surface Plasamon Resonance method alone |
|
|
Southeast University, The Affiliated Zhongda Hospital of Southeast University |
National Natural Science Foundation of China |
China |
2020-05-25 |
2021-03-19 |
ChiCTR2000032842 |
Phase 0 Clinical |
Not yet recruiting |
1 |
9 Months |
400 |
Wenjing Xu, Yewei Zhang |
2020-05-14 |
| The Geneva Covid-19 CVD Study |
Acute coronary syndrome, Cardiac failure, Coronavirus disease 19 infection, Heart arrhythmia, Myocarditis |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hopitaux Universitaires De Geneve |
|
Switzerland |
2020-03-24 |
2022-03-31 |
CCER-2020-00610, NCT04384029 |
Phase Not Applicable |
No longer recruiting |
1 |
24 Months |
7000 |
Francois MACH |
2020-05-15 |
| Inactivated Convalescent Plasma as a Therapeutic Alternative in Patients CoViD-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome, Sepsis, Septic shock, Viral pneumonia |
inactivated convalescent plasma alone, support treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Blood Center Foundation, Hemolife |
Universidad de Antioquia |
Colombia |
2020-05-20 |
2020-11-30 |
CT01, NCT04385186 |
Phase 2 Clinical |
Not yet recruiting |
10 |
6 Months |
60 |
Amanda E Maestre, MD, PhD, Ana L Muñoz, MSc, PhD, Andrés F Zuluaga, MD, MSc, MeH, Carlos A Arbélaez, MD, MSc, Daniel C Aguilar, MSc, PhD, Diego Gómez, MD, MSc, Diego Gómez, MD, Msc, Diego Gómez, MD. MSc, Fabian H Muñoz, MD, MSc, Fernando J Charries, MD, MSc, Harold Alvaréz, MD, MSc, José R Almarales, MD, MSc, Miguel G Rueda, MD, MSc |
2020-05-23 |
| COVIDBioToul: Predictive Immune Biomarkers for COVID-19 Pathogenesis |
Coronavirus disease 19 infection, Respiratory distress syndrome |
blood collection alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire de Toulouse |
|
France |
2020-05-12 |
2021-12-31 |
COVIDBioToul, NCT04385108, RC31/20/0162 |
Phase Not Applicable |
Not yet recruiting |
1 |
19 Months |
170 |
Guillaume MARTIN-BLONDEL, MD PhD |
2020-05-14 |
| COV-HI: COVID-19 Hyperinflammation Syndrome (COV-HI): Protocol for a Rapidly Executed Cohort Study |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University College London |
Newcastle Upon Tyne Hospitals NHS Trust, Nottingham University Hospital, Sheffield Teaching Hospitals NHS Foundation Trust, The Leeds Teaching Hospitals NHS Trust, England, University College London Hospital |
UK |
2020-04-16 |
2020-07-05 |
132388, COV-HI, NCT04385069 |
Phase Not Applicable |
Recruiting |
5 |
2 Months |
500 |
Amanda Ledlie, Jessica Manson, Dr, Joe West, Prof., Matthew Collin, Prof., Rachel Tattershall, Sinisa Savic |
2020-05-14 |
| Genetic Basis of COVID-19 Infection |
Coronavirus disease 19 infection |
whole exome sequencing alone |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Mansoura University |
|
Egypt |
2020-05-10 |
2021-05-01 |
NCT04384250, RP:20.05.70 |
Phase Not Applicable |
Recruiting |
1 |
11 Months |
50 |
Ali Sobh, Ali Sobh, MD, Marwa Elnagdy, MD |
2020-05-14 |
| FALP-COVID: COVID-19-Convalescent Plasma for Treating Patients With Active Symptomatic COVID-19 Infection |
Coronavirus disease 19 infection |
convalescent plasma alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Arturo Lopez Perez Foundation |
Bolsa de Santiago, Confederation for Production and Commerce of Chile (CPC) |
Chile |
2020-04-07 |
2021-04-06 |
FALP 001-2020, FALP-COVID, NCT04384588 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
12 Months |
100 |
Christian Caglevic, MD, Christian Caglevic, md, Raimundo Gazitua, MD |
2020-05-14 |
| A clinical trial to study the efficacy of homeopathic medicine in prevention and cure of Coronavirus disease 19 |
Coronavirus disease 19 infection |
arsenic album 30 alone |
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Sai Nidan Homeopathic Clinic |
|
India |
2020-05-08 |
|
CTRI/2020/05/025049 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
100 |
DR ASHISH DUBEY, DR DHIRENDRA TIWARI |
2020-05-14 |
| Levamisole and Isoprinosine in the Treatment of COVID-19: A Proposed, Therapeutic Trial |
Coronavirus disease 19 infection |
isoprinosine plus levamisole |
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cairo University |
|
Egypt |
2020-05-05 |
2020-10-30 |
LEVAMISOLE AND ISOPRINOSINE, NCT04383717 |
Phase 3 Clinical |
Not yet recruiting |
1 |
5 Months |
60 |
Hagar El Sayed, Hagar El Sayed, MD, Mohamed El Darouti, Professor |
2020-05-14 |
| POCUS: Predicting Outcomes for Covid-19 Using Sonography |
Coronavirus disease 19 infection, Viral pneumonia |
lung ultrasound alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Stanford University |
|
US |
2020-03-21 |
2020-12-31 |
IRB-55621, NCT04384055, POCUS |
Phase Not Applicable |
Recruiting |
1 |
9 Months |
200 |
Andre D Kumar, MD, MEd |
2020-05-14 |
| H-Cov-Run: HDL Target of COVID-19 ? Analysis on the Caregivers of the Reunion University Hospital |
Coronavirus disease 19 infection |
blood sampling alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire de la Réunion |
|
France |
2020-05-31 |
2021-06-30 |
2020/CHU/08, H-Cov-Run, NCT04384705 |
Phase Not Applicable |
Not yet recruiting |
1 |
13 Months |
500 |
David COURET, PH, Lucie AUZANNEAU |
2020-05-22 |
| CovidSurg-Cancer: Outcomes of Elective Cancer Surgery During the COVID-19 Pandemic Crisis |
Breast tumor, Colorectal tumor, Coronavirus disease 19 infection, Esophagus tumor, Gynecological disorder, Liver tumor, Pancreas tumor, Sarcoma, Stomach tumor, Urinary tract tumor |
elective cancer surgery alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The University of Birmingham |
Christian Medical College and Hospital |
Italy, Rwanda, Benin, South Africa, Mexico, India, UK, US, Philippines, Zambia, Ghana, Pakistan, Spain, United Arab Emirates, Canada, Australia, Nigeria, France |
2020-03-30 |
2020-12-31 |
CSC-20200324, CTRI/2020/05/025160, CovidSurg-Cancer, NCT04384926 |
Phase Not Applicable |
Recruiting |
24 |
9 Months |
1000 |
Ana Minaya-Bravo, Aneel Bhangu, Arshad Rashid, Asif Mehraj, Dhruva Nath Ghosh, Dmitri Nepogodiev, Parvez David Haque, Rohin Mittal, Shyla Sree, Stanley Mathew, Vijay Pillai |
2020-05-15 |
| CoVideo: A short, animated video to improve COVID-19 hygiene uptake: an online randomized experiment with 20,000 participants |
Coronavirus disease 19 infection |
CoVideo alone, attention placebo control (PAC) video alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
University of Heidelberg |
Heidelberg Institute of Global Health, Stanford University |
UK, Spain, France, Germany, US, Mexico |
2020-05-31 |
|
55820, CoVideo, DRKS00021582 |
Phase Not Applicable |
Not yet recruiting |
6 |
|
20000 |
Alain Vandormael, Mr. Dr Till Barnighausen, Mr. Prof Dr Till Baernighausen, Ms. Dr Maya Adam |
2020-05-14 |
| CONNAITRE: COVID-19 In Tunisia: An Observational, Cross-Sectional, Registry Study |
Coronavirus disease 19 infection |
PCR test alone, TDR test alone, clinical examination alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ministère de la Santé |
Abderrahmane Mami Hospital, Dacima Consulting, Eshmoun Clinical Research Centre |
Tunisia |
2020-05-15 |
2020-07-15 |
CONNAITRE, ECC2020-07, NCT04384614 |
Phase Not Applicable |
Not yet recruiting |
1 |
2 Months |
400 |
Agnès Hamzaoui, Pr, Chokri Jeribi, Dr, Eshmoun Clinical Research Centre |
2020-05-14 |
| Advanced Endoscopy During COVID-19 |
Coronavirus disease 19 infection, Gastrointestinal disease |
endoscopic retrograde cholangiopancreatography alone, endoscopic ultrasound alone |
|
|
Al-Azhar University |
Helwan University, National Liver Institute, Egypt |
Egypt, Germany, Peru, Singapore, US |
2020-05-18 |
2020-06-20 |
GLOBAL-ENDO-COVID, NCT04385147 |
Phase Not Applicable |
Recruiting |
5 |
1 Month |
250 |
Alejandro Piscoya, MD, MSc(Ed), AGAF, Damien Tan, MBBS, MRCP, Mohamed Alboraie, MD, MRCP(UK), Quang Trung Tran, MD., Shahzad Iqbal, MD |
2020-05-21 |
| PR-Covid-19: Clinical, Biological and Histological Pulmonary and Renal Damage Associated With the SARS-CoV-2 Syndrome in Patients Admitted in ICU |
Adult respiratory distress syndrome, Coronavirus disease 19 infection, Lung injury, Renal failure |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hopitaux Universitaires de Strasbourg |
|
France |
2020-04-27 |
2020-07-31 |
7815, NCT04385004, PR-Covid-19 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
320 |
Alexandra MONNIER, MD, Bruno MOULIN, MD, PhD, Ferhat MEZIANI, MD, PhD, Francis SCHNEIDER, MD, PhD, François SEVERAC, MD, Hamid MERDJI, MD, Julie HELMS, MD, Margaux DELLA CHIESA, MD, Michel MERTES, MD, PhD, Patrick OHLMANN, MD, PhD, Romain KESSLER, MD, PhD, Saïd CHAYER, PhD, HDR, Sophie CAILLARD, MD, PhD |
2020-05-14 |
| Convalescent Plasma for Patients With COVID-19 |
Coronavirus disease 19 infection, Dyspnea |
convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Henry Ford Health System |
|
US |
2020-05-04 |
2020-08-01 |
13807, NCT04385199 |
Phase 2 Clinical |
Recruiting |
1 |
2 Months |
30 |
Geneva Tatem, MD |
2020-05-15 |
| CoV-ICU Score, Intensive Care Unit, SARS-CoV-2 |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Bursa Yüksek İhtisas Eğitim Ve Araştırma Hastanesi |
|
Turkey |
2020-06-01 |
2020-08-31 |
BYIEAH-202005, NCT04383483 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
100 |
Ali ASAN, Associate professor, Ali Asan, MD, Erkan Sayan, MD |
2020-05-14 |
| Caards-1: Curosurf in Adult Acute Respiratory Distress Syndrome Due to COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia |
Curosurf alone, bronchial fibroscopy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Versailles University Hospital |
|
France |
2020-05-04 |
2021-01-30 |
2020-001598-66, Caards-1, NCT04384731, P20/06 |
Phase 2 Clinical |
Recruiting |
1 |
8 Months |
20 |
Christophe LENCLUD, MD, Sandrine ROUX |
2020-05-14 |
| HYDROCYCLO: Clinical Study In Which Patients Are Randomized To Receive Hydroxychloroquine versus Cyclosporine - Hydroxychloroquine To Compare Their Efficacy In The Treatment Of COVID-19 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
ciclosporin, Novartis plus hydroxychloroquine |
Calcineurin inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Infanta Sofia |
|
Spain |
2020-05-07 |
|
2020-002123-11, HUIS-04-2020, HYDROCYCLO |
Phase 4 Clinical |
Recruiting |
1 |
|
280 |
Gemma María Mora Ortega, Gonzalo Serralta San Martín, Tatiana Cobo Ibañez |
2020-05-14 |
| Convalescent Plasma for Treatment of COVID-19: An Exploratory Dose Identifying Study |
Coronavirus disease 19 infection |
SARS-CoV-2 convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Karolinska University Hospital |
Danderyd Hospital, Karolinska Institutet |
Sweden |
2020-05-07 |
2020-12-31 |
CP2, NCT04384497 |
Phase 1/Phase 2 Clinical |
Recruiting |
2 |
7 Months |
50 |
Joakim Dillner, Joakim Dillner, MD, PhD, Johan Ursing, MD, PhD, Karl Hagman, MD |
2020-05-14 |
| Neuromuscular Electrical Stimulation in Patients With COVID-19 Associated Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
Neuromuscular Electrical Stimulation alone, Routine physical therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Turin |
Azienda Ospedaliero Universitaria San Luigi Gonzaga |
Italy |
2020-04-17 |
2020-07-31 |
ESC270320, NCT04382729 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
80 |
Chiara Busso, MD, Federica Gamna, MD, Marco Alessandro Minetto, MD, PhD, Sabrina Dal Fior, MD |
2020-05-14 |
| ELVIS COVID-19: Hypertonic Saline Nasal Irrigation and Gargling in Suspected or Confirmed COVID-19 |
Coronavirus disease 19 infection |
hypertonic saline nasal irrigation and gargling alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Edinburgh |
|
UK |
2020-05-01 |
2020-07-31 |
AC20042, ELVIS COVID-19, NCT04382131 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
405 |
Aziz Sheikh, Emma Ward, Kenny Scott |
2020-05-14 |
| A two-phase clinical trial to examine the sensitivity and specificity of COVID-19 Ag Respi-Strip test to detect COVID-19 infection |
Coronavirus disease 19 infection |
COVID-19 Ag Respi-Strip test alone |
|
|
Universite Libre de Bruxelles |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
|
|
2020-05-14 |
| COVID_REHAB: Rehabilitation for People With COVID-19 in ICU |
Coronavirus disease 19 infection, Respiratory distress syndrome |
Pulmonary and Motor Rehabilitation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Padova |
Azienda Ospedaliera Universitaria Integrata Di Verona, University Hospital Padova |
Italy |
2020-05-10 |
2020-09-30 |
COVID_REHAB, NCT04381338, UPADOVA_1 |
Phase Not Applicable |
Not yet recruiting |
2 |
4 Months |
92 |
Alessandra Del Felice, MD, PhD, Katia Donadello, MD, PhD |
2020-05-15 |
| Blind, placebo-controlled, adaptive, randomized clinical trial of the efficacy and safety of the drug Allokin-alpha, lyophilisate for the preparation of a solution for subcutaneous administration (LLC Alloferon, Russian Federation) as part of complex therapy in patients with mild or moderate coronovirus infection (COVID-19) |
Coronavirus disease 19 infection |
Allokin-alpha alone |
|
|
Alloferon |
|
Russian Federation |
2020-05-28 |
2024-12-31 |
ALO001 |
Phase 3 Clinical |
Status not specified |
2 |
55 Months |
206 |
|
2020-05-20 |
| IMPACT: Using blood plasma to develop passive immunity to coronavirus in Ecuador |
Coronavirus disease 19 infection |
convalescent plasma alone, standard care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universidad Tecnológica Equinoccial |
SalvarVidasEC |
Ecuador |
2020-03-11 |
2020-12-31 |
IMPACT, ISRCTN85216856 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
9 Months |
200 |
Dr Baldeon |
2020-05-20 |
| APLICOV-PC: Proof-of-Concept Study to Evaluate the Safety Profile of Plitidepsin in Patients With COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
plitidepsin alone |
Elongation factor 1 alpha 2 modulator, VEGF-1 receptor modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
PharmaMar SA |
Apices Soluciones, S.L. |
Spain |
2020-05-12 |
2020-11-30 |
2020-001993-31, APL-D-002-20, APLICOV-PC, NCT04382066 |
Phase 1 Clinical |
Recruiting |
3 |
6 Months |
27 |
Jesús Fortún, MD, José Barberán, MD, José Barberán, Md, Maria J Pontes, María A Fores, Vicente Estrada, MD |
2020-05-18 |
| SAM-COVID: Immunosupressive Treatment in COVID-19 Patients |
Coronavirus disease 19 infection, Macrophage activation syndrome |
immunoglobulin alone, steroid therapy alone, Variable regimens including anakinra , sarilumab , tocilizumab |
IL-6 receptor antagonist, Type I IL-1 receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Spanish Network for Research in Infectious Diseases |
Fundación Pública Andaluza Para La Gestión De La Investigación En Salud De Sevilla |
Spain |
2020-05-31 |
2020-05-31 |
FIS-INM-2020-03, NCT04382781, SAM-COVID |
Phase Not Applicable |
Recruiting |
1 |
|
500 |
Jesús Rodriguez-Baño, MD, PhD, Sánchez-Barriga |
2020-05-14 |
| SAVIORII: Study Assessing Vagus Nerve Stimulation in COVID-19 Respiratory Symptoms |
Coronavirus disease 19 infection, Dyspnea, Respiratory distress syndrome |
gammaCore Sapphire alone, standard of care alone, vagus nerve stimulation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Allegheny-Singer Research Inst |
Electrocore Inc |
US |
2020-05-08 |
2020-12-30 |
2020-132-AGH, NCT04382391, SAVIORII |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
20 |
AHN Research Institute, Boyle Cheng, PhD, Clinical Trials Contact, Tariq Cheema, MD |
2020-05-14 |
| Combination of Recombinant Bacterial ACE2 Receptors-Like Enzyme of B38-CAP and Isotretinoin Could be Promising COVID-19 Infection and Lung Injury Preventing Drug Better Than Recombinant Human ACE2 |
Coronavirus disease 19 infection, Lung injury |
standard of care alone, isotretinoin plus rbACE2 |
Retinoic acid receptor agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Kafrelsheikh University |
|
Egypt |
2020-05-31 |
2020-09-30 |
COV-2019 TREATMENT THIS IS, NCT04382950 |
Phase 1 Clinical |
Not yet recruiting |
2 |
4 Months |
24 |
M.Sc. Mahmoud Elkazzaz, M.Sc.Biochemistry, M.Sc.Mahmoud Elkazzaz, M.Sc.Biochemistry, Mahmoud Ramadan mohamed Elkazzaz |
2020-05-15 |
| Novel Regimens in COVID-19 Treatment |
Coronavirus disease 19 infection |
Variable regimens including azithromycin , chloroquine (Alexoquine) , ivermectin , nitazoxanide |
Chloride channel modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tanta University |
|
Egypt |
2020-05-08 |
2030-12-01 |
NCT04382846, TANTA COVID TREATMENT |
Phase 3 Clinical |
Not yet recruiting |
1 |
126 Months |
80 |
Sherief Abd-Elsalam, ass. prof., sherief Abd-Elsalam, Ass. Prof. |
2020-05-14 |
| COVIDNOCHE: COVIDNOCHE Trial (HFNO Versus CPAP Helmet) in COVID-19 Pneumonia |
Coronavirus disease 19 infection, Hypoxia, Respiratory failure, Viral pneumonia |
helmet continuous positive airway pressure therapy alone, high flow nasal oxygen therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Pennsylvania |
|
US |
2020-05-31 |
2020-10-31 |
843124, COVIDNOCHE, NCT04381923 |
Phase Not Applicable |
Not yet recruiting |
1 |
5 Months |
200 |
Tim Gaulton, MD, MSc, Timothy Gaulton |
2020-05-14 |
| Co-infection Management in COVID-19 Critically Ill |
Coronavirus disease 19 infection, Viral pneumonia |
FilmArray Pneumonia test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Clinique Universitaires Saint-Luc, Universite Catholique de Louvain |
bioMerieux SA |
Belgium |
2020-03-23 |
2020-04-24 |
2019/14MAR/124, NCT04382092 |
Phase Not Applicable |
Completed |
1 |
1 Month |
32 |
Alexia VERROKEN, MD, PhD |
2020-05-13 |
| Ivermectin Effect on SARS-CoV-2 Replication in Patients With COVID-19 |
Coronavirus disease 19 infection |
ivermectin alone, standard care alone |
Chloride channel modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Laboratorios Phoenix SAICF |
Universidad Nacional de Quilmes, Universidad Nacional de Salta |
Argentina |
2020-05-11 |
2020-06-30 |
IVM-AR-1, NCT04381884 |
Phase 2 Clinical |
Recruiting |
1 |
1 Month |
45 |
Alejandro Krolewiecki, MD, Marcelo A Tinelli, MD, Mónica Lombardo, MD, Ricardo Valentini, MD |
2020-05-20 |
| Effect of Hydroxychloroquine on QTc Interval |
Coronavirus disease 19 infection |
hydroxychloroquine alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Sanjay Gandhi Postgraduate Institute of Medical Sciences |
|
India |
2020-05-18 |
|
CTRI/2020/05/025089 |
Phase Not Applicable |
Recruiting |
1 |
|
50 |
Dr Mohan Gurjar |
2020-05-13 |
| A Cross-sectional and Cohort Study of COVID-19 Patients With Post-discharge Dysfunction |
Coronavirus disease 19 infection, Respiratory disease |
aerobic exercise alone, airway clearance training alone, breathing training alone, chest activity training alone, health education and energy saving techniques alone, local lung dilation techniques alone, rehabilitation instruction program alone, resistance training alone, self-rehabilitation exercises alone, systematic rehabilitation treatment program alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Peking University Third Hospital |
|
China |
2020-03-10 |
2020-12-31 |
M20200421, NCT04382534 |
Phase Not Applicable |
Recruiting |
1 |
9 Months |
300 |
Yuanmingfei Zhang, Dr. |
2020-05-13 |
| ZILU-COV: Zilucoplan in Improving Oxygenation and Short- and Long-term Outcome of COVID-19 Patients With Acute Hypoxic Respiratory Failure |
Acute lung injury, Coronavirus disease 19 infection, Hypoxia, Respiratory failure |
prophylactic antibiotic therapy alone, standard of care alone, zilucoplan alone |
Complement C5 factor inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universitair Ziekenhuis Gent |
UCB SA |
Belgium |
2020-05-31 |
2021-09-30 |
NCT04382755, ZILU-COV, ZILU-COV |
Phase 2 Clinical |
Not yet recruiting |
9 |
16 Months |
81 |
Anja Delporte, Bart Lambrecht, MDPhD, Bart N. Lambrecht, Karolien Vanhove, MD, Nikolaas De Neve, MD, Wim MD Terryn |
2020-05-13 |
| COLCHI-COVID: Randomized clinical trial to investigate the efficacy of early administration of colchicine in patients > 70 years of age and at high risk of pulmonary complications such as coronavirus-associated pneumonia |
Coronavirus disease 19 infection, Lung disease, Viral pneumonia |
colchicine alone |
|
Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fundacion Instituto de Investigacion Marques de Valdecilla, IDIVAL |
|
Spain |
2020-05-06 |
|
2020-001603-16, COLCHI-COVID, COLCHI-COVID |
Phase 3 Clinical |
Recruiting |
1 |
|
1024 |
Maria del Mar Garcia, María del Mar García |
2020-05-20 |
| A phase III trial of BT-588 in Covid-19 patients |
Coronavirus disease 19 infection |
BT-588 alone |
|
|
Biotest AG |
|
|
|
|
|
Phase 3 Clinical |
Planned |
0 |
|
|
|
2020-05-12 |
| Study of GUDUCHI TABLET on healthy individuals to prevent covid 19 |
Coronavirus disease 19 infection |
guduchi alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Central Council for Research in Ayurvedic Sciences |
Ministry of Ayush |
India |
2020-05-20 |
|
CTRI/2020/05/025088 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
|
1200 |
Dr B vankatshwarlu, Dr K Anumol |
2020-05-14 |
| Covid-19 Infection and Pulmonary Distress Treatment With Zanubrutinib in Hospitalized Participants |
Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure |
supportive care treatment alone, zanubrutinib alone |
Btk tyrosine kinase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
BeiGene Co Ltd |
|
US |
2020-05-31 |
2020-09-30 |
BGB-3111-219, NCT04382586 |
Phase 2 Clinical |
Not yet recruiting |
7 |
4 Months |
52 |
BeiGene, Todd Zimmerman, MD |
2020-05-14 |
| Convalescent Plasma versus Human Immunoglobulin to Treat COVID-19 Pneumonia |
Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure, Viral pneumonia |
convalescent plasma alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centenario Hospital Miguel Hidalgo |
|
Mexico |
2020-05-06 |
2020-09-30 |
2020-A-10, NCT04381858 |
Phase 3 Clinical |
Recruiting |
1 |
4 Months |
500 |
Alejandro Castillo, MD, Jose Manuel Arreola Guerra, MD, MSc, PhD, Jose Manuel Arreola, MD,PhD, Lucila Martinez, MDPhD, Mario Gonzalez Gamez, MD, Victor Monroy, MD |
2020-05-14 |
| Observational, Cohort Study of Critically Ill Patients With Covid-19 in Sweden |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Vastmanland County Council (Landstinget) |
|
Sweden |
2020-03-26 |
2021-05-31 |
NCT04382417, REGIONVASTMANLAND |
Phase Not Applicable |
Recruiting |
2 |
14 Months |
100 |
Bjorn Sjostrom, M.D., Björn Sjöstrom, M.D., Erland Ostberg, M.D., Ph.D. |
2020-05-15 |
| ImmunoCOVID: Coronavirus Infection in Primary or Secondary Immunosuppressed Children and Adults |
Coronavirus disease 19 infection |
|
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Southampton NHS Foundation Trust |
Alder Hey Children's Hospital, Birmingham Children's Hospital NHS Foundation Trust, Bradford Royal Infirmary, Bristol Royal Hospital for Children, Cambridge University Hospitals NHS Foundation Trust, Cardiff and Vale University Health Board, East Lancashire Hospitals NHS Trust, Great North Children's Hospital, Great Ormond Street Hospital for Children NHS Foundation Trust, Imperial College Healthcare NHS trust, NHS Ayrshire And Arran, Norfolk and Norwich University Hospitals NHS Foundation Trust, Nottingham Children's Hospital, Oxford University Hospitals NHS Trust, Royal Alexandra Children's Hospital, Royal Hospital for Sick Children, Royal Manchester Children's Hospital, Royal Sussex County Hospital, Sheffield Children's NHS Foundation Trust, St George's University Hospitals NHS Foundation Trust, Swansea Bay University Health Board, The Leeds Teaching Hospitals NHS Trust, England, The Royal Marsden NHS Trust, University College London Hospitals Charity, University Hospitals Coventry & Warwickshire NHS Trust |
UK |
2020-03-22 |
2021-03-21 |
ImmunoCOVID, NCT04382508, RHM CHI1061 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
1500 |
Hans de Graaf, MD |
2020-05-21 |
| High-Dose Inhaled Nitric Oxide for COVID-19 (ICU Patients) |
Coronavirus disease 19 infection, Respiratory failure |
nitric oxide alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The University Health Network |
|
|
2020-05-31 |
2020-12-31 |
20-5449, NCT04383002 |
Phase 1 Clinical |
Not yet recruiting |
0 |
7 Months |
20 |
Jennifer Lister |
2020-05-13 |
| SIDIACO-RETRO: Sitagliptin Treatment in Diabetic COVID-19 Positive Patients |
Coronavirus disease 19 infection, Non-insulin dependent diabetes, Respiratory failure, Viral pneumonia |
sitagliptin alone |
Dipeptidyl peptidase IV inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universita degli Studi di Milano |
IRCCS Policlinico San Matteo, Istituto Clinico Humanitas, Ospedale Papa Giovanni XXIII, Ospedale dell'Angelo, Universita Degli Studi di Pavia |
Italy |
2020-05-14 |
2020-08-15 |
5/2020, NCT04382794, SIDIACO-RETRO |
Phase Not Applicable |
Recruiting |
8 |
3 Months |
200 |
Andrea Lania, MD, Angelo Guido Corsico, MD, Antonio Di Sabatino, MD, Carlo De Riva, MD, Elisabetta Lovati, MD, Marco Mirani, MD, Paolo Fiorina, MD, PhD, Roberto Trevisan, MD, Sebastiano Bruno Solerte, MD, Teresa Letizia, Dr. |
2020-05-22 |
| A Phase II, Controlled Clinical Study Designed to Evaluate the Effect of ArtemiC in Patients Diagnosed With COVID-19 |
Coronavirus disease 19 infection |
ArtemiC alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
MGC Pharmaceuticals d.o.o |
|
Israel |
2020-05-08 |
2020-07-31 |
MGC-006, NCT04382040 |
Phase 2 Clinical |
Recruiting |
2 |
2 Months |
50 |
Ameer Elemy, Elias, Ilana Aloni, Jamil Muhsan, Nadia Lisovoder, Rubi Zomer |
2020-05-16 |
| HeSAcovid: Full versus prophylactic anticoagulation for the treatment of severe forms of Covid-19 |
Coronavirus disease 19 infection |
enoxaparin sodium alone, full heparinization alone, unfractionated heparin alone |
Low molecular weight heparin |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital of the Faculty of Medicine of Ribeirão Preto |
Conselho Nacional de Desenvolvimento Cientifico e Tecnologico - CNPq |
Brazil |
2020-05-30 |
|
30958120.2.0000.5440, CEP: 4.000.967, HeSAcovid, RBR-949z6v, U1111-1251-4283 |
Phase 2 Clinical |
Recruiting |
1 |
|
30 |
Carlos Henrique Miranda |
2020-05-14 |
| Evaluation of the efficacy and safety of pharmacological inhibition of bradykinin for the treatment of Covid-19 |
Coronavirus disease 19 infection |
CE-1145 alone, icatibant alone, standard care alone |
Bradykinin B2 receptor antagonist, Complement C1s subcomponent inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universidade Estadual de Campina |
Fundacao de Amparo a Pesquisa do Estado Sao Paulo |
Brazil |
2020-04-27 |
|
3.979.595, 30227920.9.0000.5404, RBR-5s2mqg, U1111-1250-1843 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
|
180 |
Lício Augusto Velloso |
2020-05-14 |
| Egyptian Initial Experience About 2019 Novel Corona Virus: Study of 48 Patients in Alexandria-Egypt Using Chest CT |
Chronic obstructive pulmonary disease, Coronavirus disease 19 infection, Immune disorder, Interstitial lung disease, Mycobacterium tuberculosis infection, Vascular disease |
CT scanning alone |
|
|
University of Alexandria |
|
Egypt |
2020-02-01 |
2020-05-01 |
IRB (00012098), FWA (00018699), NCT04382469 |
Phase Not Applicable |
Completed |
1 |
3 Months |
48 |
Ahmed Samir, MD |
2020-05-13 |
| CórdobaTrail: Inhaled Ibuprofen to Treat COVID-19 |
Coronavirus disease 19 infection, Lung injury, Respiratory disease, Viral pneumonia |
ibuprofen alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Quimica Luar srl |
CONICET, Ceprocor - Centro De Excelencia En Prod Y Procesos De Córdoba |
Argentina |
2020-05-01 |
2021-01-31 |
CórdobaTrail, DNL000004, NCT04382768 |
Phase 2 Clinical |
No longer recruiting |
1 |
9 Months |
40 |
Dante M Beltramo, PhD, Néstor H García |
2020-05-20 |
| Examination in COVID-19 pandemic: whether endoscopies really generate aerosol particles? |
Coronavirus disease 19 infection |
endoscopy alone, handheld particle counter model 3889 alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Oita San-ai Medical Center |
|
Japan |
2020-05-11 |
|
UMIN000040353 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
50 |
Ryota Sagami |
2020-05-13 |
| Safety and Efficacy of Hydroxychloroquine Associated With Azythromycin in SARS-Cov-2 Virus |
Coronavirus disease 19 infection |
hydroxychloroquine alone, proper COVID19 treatment alone, azithromycin plus hydroxychloroquine |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
EMS SA, Hospital do Coracao |
|
Brazil |
2020-03-30 |
|
3.934.659, 30161220.0.1001.0060, RBR-9d8z6m |
Phase 3 Clinical |
Recruiting |
1 |
|
630 |
Fernando Godinho Zampieri |
2020-05-13 |
| Study of Efficacy and Safety of DV-890 in Patients With COVID-19 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
DFV-890 alone, standard of care (SOC) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Novartis AG |
|
|
2020-05-15 |
2020-07-29 |
2020-001870-32, CDFV890D12201, NCT04382053 |
Phase 2 Clinical |
Not yet recruiting |
0 |
2 Months |
120 |
Novartis Pharmaceuticals, Novartis pharmaceuticals |
2020-05-13 |
| GA and COVID19: Potential Role of Gum Arabic as Immunomodulatory Agent Among COVID 19 Patients |
Coronavirus disease 19 infection |
Acacia senegal gum arabic intake alone |
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Al-Neelain University |
University of Khartoum |
Sudan |
2020-06-01 |
2020-09-01 |
GA and COVID19, GA& COVID19, NCT04381871 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
2 |
3 Months |
110 |
Dr Babiker, PhD, Lamis Kaddam, Moawia M Mukhtar, PhD, Mustafa KM Nimeiri, MD, Shahenaz Satti, MSc |
2020-05-14 |
| Factors influencing psychological response among healthcare workers during 2020 COVID-19 pandemic |
Coronavirus disease 19 infection, Psychiatric disorder |
|
|
|
Sultan Haji Ahmad Shah Hospital |
|
Malaysia |
2020-05-18 |
2020-09-14 |
54947, NMRR-20-899-54947 |
Phase Not Applicable |
Status not specified |
1 |
3 Months |
|
Dr Ahmad Ashraf Ilman bin Zulbahri |
2020-05-13 |
| Vertical Transmission, COVID-19, Clinical Characteristics, Outcomes, Mothers, Neonates |
Coronavirus disease 19 infection |
|
|
|
Hospital Sungai Buloh |
|
Malaysia |
2020-05-11 |
2020-11-16 |
54821, NMRR-20-894-54821 |
Phase Not Applicable |
Status not specified |
1 |
6 Months |
|
Dr Lee Yee Leng, Dr See Kwee Ching |
2020-05-13 |
| COVIDIMMUNOPSY: Immunity and Infections in the Psychiatric Population |
Coronavirus disease 19 infection, Psychiatric disorder |
serological COVID-19 testing alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assistance Publique Hopitaux de Paris |
INSERM |
France |
2020-05-10 |
2020-06-25 |
APHP200553, COVIDIMMUNOPSY, NCT04381845 |
Phase Not Applicable |
Not yet recruiting |
1 |
1 Month |
200 |
France GUYOT, Marion LEBOYER, PHD |
2020-05-22 |
| Nurses Mental Healh_COVID-19 |
Coronavirus disease 19 infection, Psychiatric disorder |
|
|
|
University of Malaya |
|
Malaysia |
2020-05-15 |
2020-12-15 |
54719, NMRR-20-890-54719 |
Phase Not Applicable |
Not yet recruiting |
1 |
7 Months |
|
Dr. Chui Ping Lei |
2020-05-13 |
| A phase I trial of COVI-SHIELD to potentially treat COVID-19 |
Coronavirus disease 19 infection |
COVI-SHIELD alone |
COVID19 Spike glycoprotein inhibitor |
|
Sorrento Therapeutics Inc |
Mount Sinai Health System |
|
2020-09-30 |
|
|
Phase 1 Clinical |
Planned |
0 |
|
|
|
2020-05-21 |
| Hydroxychloroquine in SARS-CoV-2 (COVID-19) Pneumonia Trial |
Acute lung injury, Coronavirus disease 19 infection, Hypoxia, Respiratory distress syndrome, Viral pneumonia |
hydroxychloroquine alone, usual care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kootenai Health |
Washington State University |
US |
2020-05-31 |
2022-06-01 |
18244, NCT04382625 |
Phase 4 Clinical |
Not yet recruiting |
1 |
24 Months |
120 |
Jeanette Berg, MD, PhD, John Roll, PhD, Sandra Albritton, MN,RN, Sean Cook, D.O., Shamela Barnett, Sterling McPherson, PhD |
2020-05-13 |
| The Impact of COVID-19 Pandemic on Cancer Care |
Cancer, Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
El Zaitoun Specialized Hospital |
|
Egypt |
2020-05-23 |
2020-07-31 |
CANCER CARE DURING COVID-19, NCT04382495 |
Phase Not Applicable |
Not yet recruiting |
2 |
2 Months |
200 |
Aalaa Abdou, Dr, Aalaa Abdou, MSc, Ahmed Abdelaziz, MD |
2020-05-19 |
| COVID-Impact: Impact of COVID-19 on Mental Health of Health Care Workers |
Coronavirus disease 19 infection, Psychiatric disorder |
|
|
Healthy volunteers accepted |
Universitair Ziekenhuis Gent |
|
Belgium |
2020-04-17 |
2022-12-31 |
BC-07564, COVID-Impact, NCT04382196 |
Phase Not Applicable |
No longer recruiting |
1 |
32 Months |
497 |
Gilbert Lemmens |
2020-05-14 |
| Safety and Efficacy of NP-120 (Ifenprodil) for the Treatment of Confirmed COVID-19 Infected Hospitalized Patients |
Coronavirus disease 19 infection |
repurposed ifenprodil (oral, IPF/UC/IBD/crohn's disease/cough), Nash Pharmaceuticals alone, standard of care alone |
NMDA receptor epsilon 2 subunit inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Algernon Pharmaceuticals |
Novotech (Australia) Pty Ltd |
Canada, South Korea, US, Australia |
2020-07-31 |
2022-02-28 |
AGN120-3, NCT04382924 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
4 |
19 Months |
462 |
Mark Williams, Ph.D., Nancy Stewart, Ph.D. |
2020-05-19 |
| Treatment of Covid-19 Associated Pneumonia With Allogenic Pooled Olfactory Mucosa-derived Mesenchymal Stem Cells |
Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia |
allogenic pooled olfactory mucosa-derived mesenchymal stem cells alone, standard treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus |
Belarusian State Medical University |
Belarus |
2020-05-11 |
2021-06-30 |
IBCE_MSC2(COVID), NCT04382547 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
13 Months |
40 |
Andrei Y Hancharou, Dr., Eduard A Dotsenko, Dr., prof., Natalia G Antonevich, Dr. |
2020-05-14 |
| A Study of Hydroxychloroquine versus Placebo to Prevent COVID-19 Infection in Patients Receiving Radiotherapy |
Breast tumor, Central nervous system tumor, Coronavirus disease 19 infection, Gastrointestinal tumor, Gynecological disorder, Head and neck tumor, Lung tumor, Prostate tumor, Skin cancer |
hydroxychloroquine alone, standard radiation therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Memorial Sloan-Kettering Cancer Center |
|
US |
2020-05-07 |
2021-05-31 |
20-176, NCT04381988 |
Phase 2 Clinical |
Recruiting |
7 |
12 Months |
132 |
Nancy Lee, MD, Yao Yu, MD |
2020-05-14 |
| MAS-COVID: Study of Efficacy and Safety of MAS-825 in Patients With COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
MAS-825 alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Novartis AG |
|
|
2020-05-15 |
2020-11-05 |
CMAS825F12201, MAS-COVID, NCT04382651 |
Phase 2 Clinical |
Not yet recruiting |
0 |
5 Months |
120 |
Novartis Pharmaceuticals |
2020-05-14 |
| WARd-COVID: Non-invasive Ventilatory Support of Patients Affected by COVID-19 |
Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia |
continuous positive airway pressure therapy alone, high-flow nasal cannula therapy alone, non-invasive ventilation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Milano-Bicocca |
|
Italy |
2020-03-26 |
2020-06-30 |
NCT04382235, WARD-COVID, WARd-COVID |
Phase Not Applicable |
No longer recruiting |
34 |
3 Months |
900 |
|
2020-05-14 |
| An accelerated phase II study of BT-588 in COVID-19 patients |
Coronavirus disease 19 infection |
BT-588 alone |
|
|
Biotest AG |
|
|
|
|
|
Phase 2 Clinical |
Planned |
0 |
|
|
|
2020-05-12 |
| ATOMIC2: A Multicenter, Open-label, Two-arm, Randomized, Superiority Clinical Trial of Azithromycin Versus Usual Care In Ambulatory COVID-19 |
Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia |
standard usual care alone, azithromycin plus paracetamol |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Oxford |
Pfizer Inc |
|
2020-05-13 |
2020-10-13 |
20/HRA/2105, 2020-001740-26, 282892, ATOMIC2, ATOMIC2, NCT04381962 |
Phase 3 Clinical |
Not yet recruiting |
0 |
5 Months |
800 |
Lucy Cureton, Paul Little, MD PhD, Timothy SC Hinks, MD PhD |
2020-05-21 |
| COUP19: COVID-19 associated neuropathy and myopathy in Germany |
Coronavirus disease 19 infection, Myopathy, Neuropathy |
neurological and neuropyhsiological examination alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Bergmannsheil, Bochum |
University of Wurzburg, Universitätsklinikum Schleswig-Holstein |
Germany |
2020-07-01 |
|
20-6925, COUP19, DRKS00021677 |
Phase Not Applicable |
Not yet recruiting |
3 |
|
200 |
Elena Enax-Krumova, Mr. Prof. Dr. Ralf Baron, Ms. Dr. Christine Meyer-Frießem, Ms. Jun. Prof. Dr. Elena Enax-Krumova, Ms. PD Dr. Janne Gierthmühlen, Ms. Prof. Dr. Claudia Sommer, Ms. Prof. Dr. Nurcan Üçeyler, Universitätsklinikum Bergmannsheil gGmbH |
2020-05-13 |
| lnfluence of the COVID-19-pandemic on the treatment of ENT patients |
Coronavirus disease 19 infection |
|
|
|
Universitats-Augenklinik Freiburg |
|
Germany |
2020-05-12 |
|
302/20, DRKS00021699, U1111-1251-7604 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
20000 |
Sarah Riemann |
2020-05-14 |
| Ventilation@MPI: Retrospective analysis of the relationship between invasive ventilation (considering COVID-19) and a Comprehensive Geriatric Assessment (CGA) |
Coronavirus disease 19 infection, Lung disease, Viral pneumonia |
|
|
Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital of Cologne |
|
Germany |
2020-04-17 |
2020-04-30 |
20-1179, DRKS00021638, Ventilation@MPI |
Phase Not Applicable |
Completed |
1 |
|
1276 |
Maria Cristina Polidori Nelles |
2020-05-13 |
| Norwegian SARS-CoV-2 Study - Virological, Clinical and Immunological Characterisation of COVID-19 |
Coronavirus disease 19 infection |
SARS-CoV-2 PCR alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Oslo University Hospital |
Haukeland University Hospital, Ostfold Hospital Trust, St Olavs Hospital, University Hospital of North Norway, University Hospital, Akershus, Vestre Viken HF |
Norway |
2020-03-02 |
2023-12-31 |
20-04072, NCT04381819 |
Phase Not Applicable |
Recruiting |
7 |
45 Months |
1000 |
Anders B Kildal, PhD, Bjørn Blomberg, PhD, Christian Prebensen, PhD, Erik Solligård, PhD, Fredrik G Müller, Professor, Jan C Holter, PhD, Jonas Bergan, phd, Lars Heggelund, PhD, Susanne G Dudman, Ass.Professor, Susanne G Dudman, PhD, Susanne G Dudman, Professor |
2020-05-13 |
| Hydroxychloroquine in patients with mild COVID-19 illness with risk factors for severe disease |
Coronavirus disease 19 infection |
hydroxychloroquine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
All India Institute of Medical Sciences |
|
India |
2020-05-06 |
|
CTRI/2020/05/025022 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
166 |
Dr Manish Soneja |
2020-05-13 |