Last updated: May 31, 2020 - 02:00 BST

Title Indication Intervention Actions PatientSelection Sponsor Collaborator Country StartDate EndDate Identifiers Phase Recruitment Status Sites Trial Duration Enrollment Count Contacts LastChanged
A study to evaluate the effect and safety of a phytopharmaceutical drug in treatment of Coronavirus infection Coronavirus disease 19 infection purified aqueous extract of Cocculus hirsutus alone Sun Pharmaceutical Industries Ltd India 2020-06-01 CTRI/2020/05/025397, Secondary ID Registry ICR/20/005, Version No. 1.0 Phase 2 Clinical Not yet recruiting 0 210 Dr Amit Dhamija, Dr Apurva Agarwal, Dr Bhattachrya Meenakshi, Dr D Anil Kumar, Dr Harish Gupta, Dr K Vengadakrishnan, Dr Khobragade Akash Ashokkumar, Dr Maulik Doshi, Dr Md Sabah Siddiqui, Dr Parvaiz Koul, Dr Rajadhyaksha Girish Chandrakant, Dr Rakesh Patil, Dr Rohit Parate, Dr Shilpi Dhawan, Dr Shivakumar Sankaranarayanan Iyer, Dr Sushila Kataria, Guruprasad Palekar 2020-05-30
Study to find out the results of Ayurvedic Kwath & Ashwagandha churna with Yoga exercises to prevent our health workers against corona virus infection Coronavirus disease 19 infection Kiratiktadi Kwath & Ashwagandha churna alone, Yoga exercises alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) GS Ayurveda Medical College & Hospital India 2020-05-28 CTRI/2020/05/025398 Phase Not Applicable Not yet recruiting 0 30 Prof Dr Ankur Singhal 2020-05-30
Pregnancy and COVID-19 Registry Coronavirus disease 19 infection Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) ICMR National Institute for Research in Reproductive Health, Medical Education and Drugs Department India CTRI/2020/05/025423 Phase Not Applicable Not yet recruiting 0 2000 Dr Niraj Mahajan, Dr Rahul Gajbhiye, Dr Rakesh Waghmare 2020-05-30
Clinical features and outcome of COVID-19 and non-COVID respiratory infection Coronavirus disease 19 infection, Respiratory tract infection, Viral pneumonia Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) Christian Medical College, Vellore, India India 2020-06-04 CTRI/2020/05/025424 Phase Not Applicable Not yet recruiting 0 100 Leni G Mathew 2020-05-30
Ayurvedic intervention (Chyawanprash) in the prevention of COVID-19 pandemic among Health Care Personnel Coronavirus disease 19 infection Chayavanprash alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Central Council for Research in Ayurvedic Sciences Ministry of Ayush India 2020-06-02 CTRI/2020/05/025425 Phase 4 Clinical Not yet recruiting 0 50 Dr BabitaYadav, Dr Nitin Jindal, Dr Shivshankar Rajput 2020-05-30
SCB-2019 as COVID-19 Vaccine Coronavirus disease 19 infection SCB-2019 alone, Variable regimens including AS03 adjuvant , CpG 1018 adjuvant , SCB-2019 , alum adjuvant Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Clover Biopharmaceuticals AUS Pty Ltd 2020-06-20 2021-03-30 CLO-SCB-2019-001, NCT04405908 Phase 1 Clinical Not yet recruiting 0 9 Months 150 Min Dong 2020-05-29
Clinical Characteristics and Outcomes of Patients Admitted with Severe Acute Respiratory Illness Coronavirus disease 19 infection, Respiratory disease Mazumdar Shaw Medical Foundation India 2020-05-30 CTRI/2020/05/025427 Phase Not Applicable Not yet recruiting 9 200 Amarja Havaldar, Chandan, Dr Murthy, Farookh Khan, Gagan Brar, Jose Chacko, Rajesh Shetty, Shashidhar, Venkatesh Gupta 2020-05-30
CLIPSI study: COVID -19 Pandemic and Lockdown : Impact on Parents Stress level, Infant care and follow-up Acute stress disorder, Coronavirus disease 19 infection Healthy volunteers accepted, Newborn Infants (up to 5 months) Sri Ramachandra Institute of Higher Education and Research India 2020-05-29 CLIPSI study, CTRI/2020/05/025428 Phase Not Applicable Not yet recruiting 1 300 Usha Devi R 2020-05-29
Prediction of Acute Kidney Injury in Patients With COVID-19 Coronavirus disease 19 infection, Renal injury, Respiratory distress syndrome Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Muenster Germany 2020-05-25 2021-03-31 04-ANIT-20, NCT04406688 Phase Not Applicable Not yet recruiting 1 10 Months 300 Alexander Zarbock, MD, Melanie Meersch, MD 2020-05-29
Effect of Ashwagandha (Withania somnifera) as a prophylactic measure among high risk population (Health Care Workers/Containment Zone Population) exposed to COVID-19 Coronavirus disease 19 infection Ashwagandha capsule alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Central Council for Research in Ayurveda and Siddha India 2020-10-06 CTRI/2020/05/025429 Phase 2/Phase 3 Clinical Not yet recruiting 1 5000 Dr PVV Prasad, Dr T Saketh Ram 2020-05-29
Evaluation the anti-inflammatory effects of curcumin in the treatment of patients with COVID-19 Coronavirus disease 19 infection common therapeutic protocol alone, nano-curcumin alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ahvaz University of Medical Sciences Iran 2020-06-05 IR.AJUMS.REC.1399.176, IRCT20200519047510N1 Phase 3 Clinical Not yet recruiting 1 60 Ali Asadirad, Mohammad Badavi, Roohangiz Nashibi 2020-05-29
Prevention of Infection and Incidence of COVID-19 in Medical Personnel Assisting Patients With New Coronavirus Disease Coronavirus disease 19 infection bromhexine hydrochloride alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health Russian Federation 2020-05-14 2020-09-30 05-20-02-С, NCT04405999 Phase 4 Clinical Recruiting 1 4 Months 140 Evgeny Mikhailov, MD, PhD, Evgeny Shlyakhto, MD, PhD, Tamara Lyubimtseva, MD 2020-05-29
CONFI-LOMB: Confinement Effect on Low Back Pain Intensity in Chronic Low Back Pain Patients Coronavirus disease 19 infection, Lower back pain Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Angers France 2020-06-02 2020-06-21 CONFI-LOMB, CONFI-LOMB, NCT04406363 Phase Not Applicable Not yet recruiting 1 300 Audrey Petit, PhD 2020-05-29
This Study Examines the Use of Disinfectants by Egyptian Women During the Coronavirus Lockdown and How They Seak Medical Advice for Adverse Reactions Related to the Use of Disinfectants Coronavirus disease 19 infection, Toxicity disinfectant usage alone, online survey alone Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Helwan University University of Nebraska Egypt 2020-05-31 2020-07-01 COVID2020_HELWANU_01, NCT04405284 Phase Not Applicable Not yet recruiting 1 1 Month 100 Maha M Farid, PhD, Wael M ElRayes, PhD 2020-05-29
COVADO: Psychological Impact of the Health Measures Generated by the COVID19 in Adolescents Coronavirus disease 19 infection, Psychiatric disorder interview alone Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Centre Hospitalier Intercommunal Creteil France 2020-05-27 2020-11-30 COVADO, COVADO, NCT04406558 Phase Not Applicable Recruiting 1 6 Months 400 Adele CARLIER-GONOD, MD, Camille JUNG, MD PhD 2020-05-29
A follow up research of exercise, cardiopulmonary and quality of Life for patients of novel coronavirus pneumonia Coronavirus disease 19 infection pulmonary rehabilitation program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Anhui Provincial Hospital China 2020-05-01 2021-05-20 ChiCTR2000033319 Phase Not Applicable Recruiting 1 12 Months 85 Ming Wu, Yang Zhang 2020-05-29
ArcHIV - SARS-CoV-2 IgG: Study platform ArcHIV - Substudy on SARS-CoV-2 (COVID-19) IgG antibody prevalence in an HIV cohort Coronavirus disease 19 infection, HIV infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) MUC Research GmbH Lab4More GmbH Germany 2020-05-29 13112 Substudie zu ArcHIV Studienplattform, ArcHIV - SARS-CoV-2 IgG, DRKS00021737, DRKS00021752 Phase Not Applicable Not yet recruiting 1 500 Celia Jonsson-Oldenbüttel, Eva Wolf, Sebastian Noe 2020-05-29
Epidemiological and Clinical Characteristics of 20 Re-positive novel coronavirus pneumonia (COVID-19) Patients Coronavirus disease 19 infection anti-virus treatment alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Affiliated Hospital of Zunyi Medical College The Science and Technology Department of Guizhou Province China 2020-01-29 2020-04-30 ChiCTR2000033347 Phase 1 Clinical No longer recruiting 1 3 Months 20 Zhang Wei 2020-05-29
Erythrocyte Sedimentation Rate in novel coronavirus pneumonia (COVID-19) patients Coronavirus disease 19 infection Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Affiliated Hospital of Zunyi Medical College The Science and Technology Department of Guizhou Province China 2020-02-29 2020-05-12 ChiCTR2000033346 Phase 1 Clinical No longer recruiting 1 2 Months 80 Zhang Wei 2020-05-29
CA-COVID19: Coagulopathy in COVID19 - A Multicenter, Observational Study in UK (COVID19) Bleeding, Coronavirus disease 19 infection, Thrombosis Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Imperial College London UK 2020-05-21 2021-06-20 20SM5934, CA-COVID19, NCT04405232 Phase Not Applicable Recruiting 1 13 Months 5000 Dr Deepa Jayakody Arachchillage, FRCPath, MD 2020-05-29
Study for the effect of Traditional Chinese medicine in the prevention of novel coronavirus pneumonia (COVID-19) in the high risk area Coronavirus disease 19 infection Chushifangyi prescription alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Affiliated Hospital of Changchun University of Traditional Chinese Medicine China 2020-05-29 2020-12-31 ChiCTR2000033345 Phase Not Applicable Not yet recruiting 1 7 Months 10000 Liu Yangyang, Shi Li 2020-05-29
Efficacy of Liu-zi-jue in Patients with 2019 Novel Coronavirus Pneumonia (COVID-19): a randomized controlled trial Coronavirus disease 19 infection Liu--zi-jue alone, conventional treatment alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shanghai University of Traditional Chinese Medicine, Yueyang Xinhua Pharmaceutical Co Ltd China 2020-02-20 2020-12-30 ChiCTR2000033318 Phase Not Applicable Recruiting 1 10 Months 104 Min Fang, Shuaigpan Zhang 2020-05-29
The Effect of EIDD-2801 on Viral Shedding of SARS-CoV-2 Coronavirus disease 19 infection, Dysomia, Viral pneumonia EIDD-2801, Drug Innovation Ventures/Georgia State University/Emory University alone RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ridgeback Biotherapeutics LP 2020-05-26 2020-07-13 EIDD-2801-2004, NCT04405739 Phase 2a Clinical Not yet recruiting 0 1 Month 80 Laura Szewczyk 2020-05-29
Clinical Scores for Outcome Prediction in Patients With Severe COVID-19 Pneumonia Requiring ECMO Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia veno-venous extracorporeal membrane oxygenation therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Klinikum der Albert-Ludwigs Universitaet Freiburg Germany 2020-05-19 2020-08-31 EK-FR 329/20, NCT04405973 Phase Not Applicable Recruiting 1 3 Months 100 Alexander Supady, Dr., MPH, Alexander Supady, MD, MPH, Dawid Staudacher, MD 2020-05-29
Determination of Acute Encephalopathy Predictors in Patients With COVID-19 Brain disease, Coronavirus disease 19 infection, Viral pneumonia Blood test alone, Electroencephalography alone, Pulse oximetry alone, chest CT-scan alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Ministry of Health and Social Development of the Russian Federation, Pirogov National Medical Surgical Center, State Budgetary Healthcare Institution Russian Federation 2020-05-22 2020-10-22 NCT04405544, NMSC-01-20 Phase Not Applicable Recruiting 1 5 Months 60 Oleg I Vinogradov, MD, PhD 2020-05-29
COVICLOT: Thromboembolic Events in Severe COVID-19 Patients Coronavirus disease 19 infection, Thromboembolism Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopitaux Universitaires de Strasbourg France 2020-04-29 2021-04-30 7779, COVICLOT, NCT04405869 Phase Not Applicable Recruiting 1 12 Months 300 Alexandre GODON, MD, Alexandre MANSOUR, MD, Anne Claude ROCHE, MD, Anne GODIER, MD, PhD, Annick STEIB, MD, PhD, Bélaïd BOUHEMAD, MD, PhD, Charles TACQUARD, MD, Cécile AUBRON, MD, PhD, Delphine GARRIGUE, MD, Eric KIPNIS, MD, PhD, Isabelle GOUIN-THIBAULT, MD, Julien POISSY, MD, PhD, Lea RYFFEL, MD, Maxime NGUYEN SOENEN, MD, Pierre ALBALADEJO, MD, PhD, Saïd CHAYER, PhD, HDR, Sophie SUSEN, MD, PhD, Stephan MANKIKIAN, MD 2020-05-30
A Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Baicalein in Hospitalized Adult Patients With Mild and Moderate 2019-nCoV Respiratory Disease Coronavirus disease 19 infection Baicoli alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chinese Academy of Medical Sciences & Peking Union Medical College, Xiangyang Central Hospital China 2020-02-15 2020-03-09 ChiCTR2000033286 Phase 2/Phase 3 Clinical Completed 2 60 Chaoqing Wang, Xiansheng Zeng 2020-05-29
COZI: COVID-19 Ozanimod Intervention Study Coronavirus disease 19 infection, Hypoxia, Viral pneumonia anticoagulation therapy alone, antipyretics agent therapy alone, antiviral agent therapy alone, corticoid therapy alone, fluid resuscitation alone, immunomodulator therapy alone, ozanimod alone, standard of care alone Sphingosine-1-phosphate receptor-1 agonist, Sphingosine-1-phosphate receptor-5 agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Universite Laval Bristol-Myers Squibb Co, Celgro Corp Canada 2020-07-06 2022-07-06 2021-3474, COZI, NCT04405102 Phase 2 Clinical Not yet recruiting 2 24 Months 48 David Marsolais, PhD, Francois Lellouche, Francois Lellouche, MD, Nathalie Chateauvert, B. pharm, Pascale Blais-Lecours, PhD 2020-05-29
'Pirfenidone XR as a protector in patients with COVID-19' Coronavirus disease 19 infection pirfenidone XR alone Instituto Nacional de Ciencias Medicas y Nutricion Mexico 3381 Phase 3 Clinical Status not specified 1 801 2020-05-29
The comprehensive evaluation of therapeutic drugs for pediatric novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection traditional Chinese medicine alone Children's Hospital of Fudan University China 2020-06-15 2020-11-30 ChiCTR2000033342 Phase Not Applicable Not yet recruiting 12 5 Months 100 Zhiping Li 2020-05-29
IMPACT: Anticoagulation in Critically Ill Patients With COVID-19 Blood clotting disorder, Coronavirus disease 19 infection argatroban alone, enoxaparin sodium alone, fondaparinux sodium alone, unfractionated heparin alone Factor IIa antagonist, Factor Xa antagonist, Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Weill Medical College of Cornell University US 2020-06-30 2021-06-30 20-04021936, IMPACT, NCT04406389 Phase 4 Clinical Not yet recruiting 1 12 Months 186 Maria T DeSancho, MD, MSc, Marina Loizou 2020-05-29
Severe Reluctant COVID-19 Patients Responding to Convalescent Plasma; A case series Coronavirus disease 19 infection convalescent plasma therapy alone Middle-aged Adults (45-64 yrs) University of Sulaimani Iraq 2020-05-11 2020-05-19 ChiCTR2000033323 Phase Not Applicable No longer recruiting 1 24 Fahmi Hussein Kakamad, Rawezh qadr 2020-05-29
The Effectiveness of Telerehabilitation-Based Physiotherapy in COVID 19 Patients Coronavirus disease 19 infection telerehabilitation physical therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Istanbul Medipol University Hospital Saglik bilimleri universtesi Turkey 2020-05-20 2020-12-01 NCT04402983, TELEREHAB_COVID19 Phase Not Applicable Recruiting 1 6 Months 34 Esra Pehlivan, PhD 2020-05-29
Study for Traditional Chinese Medicine in the treatment of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection Traditional Chinese Medicine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Shuguang Hospital Shanghai University Of Traditional Chinese Medicine Shanghai Committee of Science and Technology China 2020-03-27 2020-12-31 ChiCTR2000033320, ChiMCTR2000003347 Phase 0 Clinical Recruiting 1 9 Months 300 Zhang Wei 2020-05-29
Viral Specific T-cells for Treatment of COVID-19 Coronavirus disease 19 infection viral specific T-cells alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cincinnati Children's Hospital Medical Center Hoxworth Blood Center US 2020-06-30 2025-06-30 2020-0353, NCT04406064 Phase 2 Clinical Not yet recruiting 1 60 Months 100 Adam Nelson, MBBS, FRACP, Celeste Dourson, MS, Jamie Wilhelm, BS 2020-05-29
Survival and risk factors in COVID-19 and influenza, a retrospective analysis Coronavirus disease 19 infection, Influenza virus infection Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie (DE) Universitat des Saarlandes Germany 2020-05-29 78/20, DRKS00021823 Phase Not Applicable Not yet recruiting 1 18000 Mr. Prof. Dr. Sascha Kreuer 2020-05-29
Home-Based Covid-19 Rehabilitation Program Coronavirus disease 19 infection PT-Pal guided exercise alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Albert Einstein College of Medicine US 2020-07-01 2021-03-01 2020-11535, NCT04406532 Phase Not Applicable Not yet recruiting 1 8 Months 100 Anne F Ambrose, MD, Emmeline Ayers, MPH, Joe Verghese, MBBS 2020-05-29
Stellate Ganglion Block (SGB) for COVID-19 Acute Respiratory Distress Syndrome (ARDS) Coronavirus disease 19 infection, Respiratory distress syndrome Stellate Ganglion Block alone, Variable regimens including bupivacaine, AstraZeneca , dexamethasone , lidocaine Sodium channel inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) West Virginia University US 2020-04-24 2020-12-31 2004963113, NCT04402840 Phase 2 Clinical Recruiting 1 8 Months 5 Ali R Rezai, MD, Ali Rezai, Padma Tirumalai, PhD 2020-05-29
MEMO-COV2: COVID-19: SARS-CoV-2 Specific Memory B and T-CD4+ Cells Coronavirus disease 19 infection blood sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-06-01 2021-03-01 APHP200551, MEMO-COV2, NCT04402892 Phase Not Applicable Not yet recruiting 1 9 Months 60 MAHEVAS Matthieu, PHD 2020-05-29
Psychiatric admissions during the COVID-19 pandemic Coronavirus disease 19 infection, Psychiatric disorder psychological assessment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) China 2020-05-25 2021-07-31 ChiCTR2000033317 Phase Not Applicable Not yet recruiting 1 14 Months 10000 Allen Ting Chun LEE 2020-05-29
ERap-COV: Evaluation of Rapid Diagnostic Solutions, Serological and Molecular Tests for COVID-19 Coronavirus disease 19 infection ELISA alone, biological sampling alone, rapid diagnostic test (NG Biotech) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-05-25 2021-03-25 APHP200556, ERap-COV, NCT04405492 Phase Not Applicable Not yet recruiting 2 10 Months 1210 Anne-Marie Roque-Afonso, Thierry Naas 2020-05-29
A clinical study to assess the efficacy of Neumifil in the treatment of patients with COVID-19 infection Coronavirus disease 19 infection Neumifil alone Pneumagen Ltd 2021-06-30 Phase Not Applicable Planned 0 2020-05-29
A multinational, double-blind, randomized, phase II clinical study to assess the effect of ATR-002 in the treatment of COVID-19 patients Coronavirus disease 19 infection ATR-002 alone MEK protein kinase inhibitor Atriva Therapeutics GmbH Evonik Industries AG 2020-07-31 Phase 2 Clinical Planned 0 2020-05-29
CoviPrep Study: TAF/FTC for Pre-exposure Prophylaxis of COVID-19 in Healthcare Workers Coronavirus disease 19 infection emtricitabine + tenofovir alafenamide alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hospital Italiano de Buenos Aires Sociedad Argentina de Infectología Argentina 2020-06-15 2020-11-15 16052020, CoviPrep Study, NCT04405271 Phase 3 Clinical Not yet recruiting 1 5 Months 1378 Diego H Giunta, PhD, Elvira Zini, MD, Esteban Nannini, MD, Fernando Riera, MD, Gonzalo Corral, MD, Gustavo Costilla Campero, MD, Gustavo D Lopardo, MD, Marcelo Figueiras, MD, Omar Sued, MD, Santiago Ramirez Borga, MD, Ventura Simonovich, MD, Waldo H Belloso, MD, Wanda Cornistein, MD 2020-05-29
Study on the improvement the quality of life of severe patients with COVID-19 by the integrated treatment with Chinese medicine and Western medicine Coronavirus disease 19 infection chinese herbal medication alone, pirfenidone alone, traPirfenidone alone, traditional Chinese Medicine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Guangzhou Women and Children's Medical China 2020-06-01 2025-05-31 ChiCTR2000033284 Phase 0 Clinical Not yet recruiting 2 60 Months Zhang Shunxian 2020-05-29
Study of the Spread of COVID-19 in Saint Petersburg, Russia Coronavirus disease 19 infection SARS-CoV-2-specific antibodies test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) European University at St. Petersburg Clinic “Scandinavia” (LLC Ava-Peter) Russian Federation 2020-05-27 2020-10-28 CDRU-001, ISRCTN11060415, NCT04406038 Phase Not Applicable Recruiting 1 5 Months 1550 Anton Barchuk, MD, Daniil Shirokov, Dr Dmitriy Skougarevskiy, Lubov Barabanova, MD 2020-05-30
Monitoring COVID-19 Patients' Lung Fluid Using Impedance Technique Coronavirus disease 19 infection lung impedance technique alone, x-ray alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hillel Yaffe Medical Center Israel 2020-04-28 2021-04-28 0059-20-HYMC, NCT04406493 Phase Not Applicable Recruiting 1 12 Months 50 Michael Cleiner, M.D, Michael Cleiner, M.D. 2020-05-29
CPC-SARS: Convalescent Plasma of Covid-19 to Treat SARS-COV-2 a Randomized, Doble-Blind, Two-Center Trial Coronavirus disease 19 infection, Hypoxia, Viral pneumonia Variable regimens including azithromycin , convalescent plasma , hydroxychloroquine Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hospital General Naval de Alta Especialidad Instituto Nacional de Enfermedades Respiratorias, National Institute of Pediatrics Mexico 2020-05-20 2020-07-20 CPC-SARS, DI/20/201/04/19, NCT04405310 Phase 2/Phase 3 Clinical Recruiting 2 2 Months 80 AMALIA BRAVO-LINDORO, MS, ANGEL A PEREZ-CALATAYUD, MD, ANGEL AUGUSTO PEREZ-CALATAYUD, MD, Angel Augusto Perez Calatayud, BALTAZAR PECH-ALONSO, MD, CARLOS CABELLO-GUTIERREZ, PHD, CARLOS PEÑA-PEREZ, MD, CATALINA CASILLAS-SUAREZ, PHD, EVELYN CORTINA-DE LA ROSA, MS, JOSE CARRILLO RUIZ, PhD, KARLA MALDONADO-SILVA, MD, ORLANDO CARILLO-TORRES, PHD, ORLANDO CARRILLO-TORRES, PHD, RAUL CARRILLO-ESPER, MD, SANDRA MURRIETA, MD, VERONICA FERNANDEZ-SANCHEZ, PHD, YANET VENTURA, MD, YANET VENTURA-ENRIQUEZ, MD 2020-05-29
Efficacy of Ivermectin in Adult Patients With Early Stages of COVID-19 Coronavirus disease 19 infection ivermectin alone Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centro de Estudios en Infectogía Pediatrica Colombia 2020-06-30 2020-11-01 NCT04405843, SCDI823 Phase 2/Phase 3 Clinical Not yet recruiting 1 4 Months 400 2020-05-29
Muscle Mass and Strength as Predictors of Time to Discharge in Patients With COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Sao Paulo Brazil 2020-05-23 2022-05-23 31303720.7.0000.0068, NCT04406233 Phase Not Applicable Recruiting 1 24 Months 176 Bruno Gualano, Phd 2020-05-29
Prospective, observational study on cytokine removal effect of continuous hemodiafiltration in COVID-19 Coronavirus disease 19 infection continuous hemodiafiltration alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Juntendo University Japan 2020-05-18 UMIN000040563 Phase Not Applicable Recruiting 1 20 Junichiro Nakata 2020-05-29
Co-SURVIVORS: COVID-19: Respiratory and Sleep Follow-up Coronavirus disease 19 infection, Post traumatic stress disorder, Sleep disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Grenoble France 2020-06-05 2026-03-05 38RC20.157, Co-SURVIVORS, NCT04406324 Phase Not Applicable Not yet recruiting 4 69 Months 400 Anne-Laure Mounayar, MD, Bruno Chenuel, MD, Pr, Carole Planes, MD, Pr, Genevieve Derumeaux, MD, Pr, Jean-Louis Pepin, MD, Pr, PhD, Marie Destors, MD, Nicolas Terzi, MD, Pr, Renaud Tamisier, MD, PhD, MBA, Renaud Tamisier, MD, Pr, PhD, Sam Bayat, MD, Pr, PhD 2020-05-29
Investigation of Systemic Microvascular Flow and Reactivity in Patients Presenting in the Acute Phase of Coronavirus Disease-19 Cardiovascular disease, Coronavirus disease 19 infection skin laser Doppler perfusion monitoring alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto Nacional de Cardiologia Brazil 2020-05-15 2020-11-30 #CAAE 31237220.1.0000.5272, NCT04406545 Phase Not Applicable Recruiting 1 6 Months 25 Eduardo Tibirica, Eduardo Tibirica, MD, PhD 2020-05-29
A Study to Assess the Feasibility of Screening for SARS-CoV-2 Among Healthy Workers Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Miltenyi Biotec B.V. & Co. KG Germany 2020-04-22 2021-01-31 M-2020-360, NCT04405466 Phase Not Applicable Recruiting 1 9 Months 500 Barbara von Ingersleben, Dr., Sandra Karitzky, Dr. 2020-05-29
REMDACTA: A two-armed, global, phase III, randomized, double-blind, multicenter study to evaluate the efficacy and safety of Actemra plus remdesivir versus placebo plus remdesivir in hospitalized patients with severe COVID-19 pneumonia receiving standard of care (SOC) Coronavirus disease 19 infection, Viral pneumonia standard of care (SOC) alone, remdesivir plus tocilizumab (intravenous), Roche/Chugai COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, IL-6 receptor antagonist, IL-6 receptor modulator, RNA polymerase modulator Genentech Inc Gilead Sciences Inc US, Europe, Canada 2020-05-28 REMDACTA Phase 3 Clinical Not yet recruiting 2 450 2020-05-29
ET-COVID-19: Endovascular Thrombectomy in COVID-19 Infected Patients Coronavirus disease 19 infection, Ischemic stroke mechanical thrombectomy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Montpellier France 2020-04-01 2020-06-30 ET-COVID-19, NCT04406090, RECHMPL20_0322 Phase Not Applicable Recruiting 1 3 Months 50 Federico Cagnazzo, MD, Federico Cagnazzo, MD PhD, Vincent COSTALAT, PhD, MD, MSc 2020-05-29
QUARCOPSY: Consequences of the QUARANTINE Relating to the Covid-19 Epidemic on the Mental Health of the Patients Followed in Psychiatry Anxiety disorder, Coronavirus disease 19 infection, Mood disorder, Personality disorder, Post traumatic stress disorder, Psychotic disorder, Somatoform disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Regional Universitaire de Lille 2020-05-31 2021-05-31 2020-A01186-33, 2020_39, NCT04405362, QUARCOPSY Phase Not Applicable Not yet recruiting 0 12 Months 753 Arnaud Leroy, MD 2020-05-29
The Impact of quarantine and social distancing on mental health in the context of the Covid-19 pandemic Coronavirus disease 19 infection, Psychiatric disorder exercise alone, social support alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Eberhard Karls Universität Tübingen Germany 2020-04-08 A2.5.4-120_kr, DRKS00021791 Phase Not Applicable No longer recruiting 1 Sebastian Wolf 2020-05-29
Prevention of Coronavirus Disease (COVID-19) Outbreaks With Nitazoxanide Coronavirus disease 19 infection nitazoxanide alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Materno-Perinatal Hospital of the State of Mexico Laboratorios Liomont Sa De Cv Mexico 2020-05-21 2020-12-31 2020-04-682, NCT04406246 Phase 4 Clinical Recruiting 1 7 Months 150 Hugo Mendieta Zeron, PhD, Hugo Mendieta Zerón, MD., PhD., José Meneses Calderón, MD, José Meneses Calderón, MD., Marlen Santamaría Benhumea, PhD., Nancy Santamaría Benhumea, Bachelor in Law 2020-05-29
PACTT: Hydroxychloroquine, Azithromycin in the Treatment of Covid-19 Coronavirus disease 19 infection, Viral pneumonia standard of care alone, azithromycin plus hydroxychloroquine Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Farhat Hached University Hospital Tunisia 2020-05-31 2021-03-31 NCT04405921, PACTT, PACTT Phase 3 Clinical Not yet recruiting 1 10 Months 200 Amel Letaief, Amel Letaief, Professor 2020-05-29
COVID-HUS: Clinical, Biological and Genetic Prognostic Factors for SARS-CoV-2 Infection in Patients Hospitalized in Strasbourg Coronavirus disease 19 infection Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopitaux Universitaires de Strasbourg France 2020-03-27 2022-03-31 7760, COVID-HUS, NCT04405726 Phase Not Applicable Recruiting 1 24 Months 500 Aurélie VELAY, MD, Eric SOULIER, InG, Floriane GALLAIS, MD, François DANION, MD, Héloïse DELAGREVERIE, MD, Ilies BENOTMANE, MD, Morgane SOLIS, MD, Nicolas LEFEBVRE, MD, Nicolas MEYER, MD, PhD, Samira FAFI-KREMER, PharmD, PhD, Saïd CHAYER, PhD, HDR, Yves HANSMANN, MD, PhD, Yvon RUCH, MD 2020-05-29
A global, multicenter, randomized, double-blinded, placebo-controlled trial to assess the efficacy, safety and tolerability of LYT-100 in non-critical COVID-19 patients with respiratory complications Coronavirus disease 19 infection, Fibrosis, Inflammatory disease, Respiratory disease deupirfenidone alone PDGF receptor antagonist, TGF beta receptor antagonist, p38 MAP kinase inhibitor PureTech Health Plc 2020-09-23 Phase Not Applicable Planned 0 150 2020-05-29
CAPANCOVID-19: Reorganization of the Healthcare System During COVID-19 Pandemic: Impact on Management of Patients With Exocrine Pancreatic Cancer Adenocarcinoma, Coronavirus disease 19 infection, Pancreas tumor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire de Reims France 2020-04-01 2022-04-30 CAPANCOVID-19, NCT04406571, PO20042 Phase Not Applicable Recruiting 1 25 Months 700 Olivier BOUCHE 2020-05-29
Investigating the efficacy of Provita Capsule in controlling the symptoms of patients with COVID-19 Coronavirus disease 19 infection, Cough, Dyspnea, Fever Provita alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Bagheiat-allah University of Medical Sciences, TAK GENE ZIST Baqiyatallah University of Medical Sciences Iran 2020-05-14 IR.BMSU.REC.1399.124, IRCT20080901001165N60 Phase 3 Clinical Recruiting 1 30 Gholamhosein Alishiri, Maryam Tajabadi, Mostafa Ghanei, Parisa Kianpour, Seyed Hasan Saadat, Yunes Panahi 2020-05-29
Dose-Confirmation Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1273 COVID-19 Vaccine in Adults Aged 18 Years and Older Coronavirus disease 19 infection mRNA-1273 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) ModeRNA Therapeutics Biomedical Advanced Research and Development Authority (BARDA), US Department of Health and Human Services US 2020-05-25 2021-08-31 75A50120C00034, MRNA-1273-P201, NCT04405076 Phase 2a Clinical Recruiting 10 15 Months 600 Moderna Clinical Trials 2020-05-29
A Safety, Tolerability and Efficacy of EIDD-2801 to Eliminate Infectious Virus Detection in Persons With COVID-19 Coronavirus disease 19 infection EIDD-2801, Drug Innovation Ventures/Georgia State University/Emory University alone RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ridgeback Biotherapeutics LP US 2020-05-26 2020-07-13 EIDD-2801-2003, NCT04405570 Phase 2a Clinical Not yet recruiting 1 1 Month 44 Laura Szewczyk, Susan Pedersen, William Fischer 2020-05-29
IMPACT SMI-COVID-19 Survey: Investigating the impact of COVID-19 and its response, on people with severe mental illness in South Asia Bipolar disorder, Coronavirus disease 19 infection, Depression, Schizoaffective disorder, Schizophrenia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of York National Institute for Health Research (NIHR) Pakistan, Bangladesh, India 2020-04-10 2022-02-01 IMPACT SMI-COVID-19 Survey, ISRCTN15571919, NIL KNOWN Phase Not Applicable Recruiting 6 21 Months 2000 Dr Zavala 2020-05-29
Multi-site audit of COVID-19 airway interventions Coronavirus disease 19 infection airway intervention alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) St Vincents Hospital Sydney Ltd Australia 2020-04-30 2021-03-27 ACTRN12620000617965 Phase Not Applicable Recruiting 1 10 Months 100 Dr Erez Ben-Menachem 2020-05-29
In a simulation environment, is there a difference in time taken for consultant anesthetists to perform spinal anaesthesia as compared to general anesthesia on women, with suspected or confirmed COVID-19, who require emergency cesarean delivery? Coronavirus disease 19 infection general anesthesia simulation alone, spinal anesthesia simulation alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mackay Base Hospital Australia 2020-05-20 2020-06-01 ACTRN12620000579998, U1111-1251-9551 Phase Not Applicable Not yet recruiting 1 10 Dr Marcelo Epsztein Kanczuk 2020-05-29
TROCAR: Tocilizumab for treatment Of COVID-19 in intensive care patients Coronavirus disease 19 infection tocilizumab (intravenous), Roche/Chugai alone IL-6 receptor antagonist, IL-6 receptor modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Queensland Institute of Medical Research Australia 2020-05-26 ACTRN12620000580976, TROCAR Phase 1/Phase 2 Clinical Not yet recruiting 4 150 A/Prof Bridget Barber 2020-05-29
Post-Intensive Care Nutrition Status in Patients with COVID-19 Coronavirus disease 19 infection, Malnutrition Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Australian and New Zealand Intensive Care Research Centre Australia 2020-05-29 ACTRN12620000602921 Phase Not Applicable Not yet recruiting 9 200 Dr Emma Ridley 2020-05-29
Covid-19 Biobank of clinical samples and data for use in research to help understand the immune characteristics of people who are diagnosed with COVID19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Alfred Health Lord Mayor's Charitable Foundation Australia 2020-04-16 ACTRN12620000609954, U1111-1252-1632 Phase Not Applicable Recruiting 6 250 Dr James McMahon, Ms Janine Roney 2020-05-29
The MEND Trial: The MEND (MEseNchymal coviD-19) Trial: a pilot study to investigate early efficacy of mesenchymal stem cells in adults with COVID-19 Coronavirus disease 19 infection mesenchymoangioblast-derived mesenchymal stem cell therapy (Cymerus, critical limb ischemia/graft versus host disease/asthma/diabetic foot ulcer), Cynata/FUJIFILM alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cynata Therapeutics Ltd Cerebral Palsy Alliance Research Foundation Australia 2020-06-01 ACTRN12620000612910, The MEND Trial Phase 1/Phase 2 Clinical Not yet recruiting 2 24 A/Prof Vineet Nayyar, Dr Kilian Kelly, Dr Madison Paton 2020-05-29
Validation of COVID-19 Tests Coronavirus disease 19 infection RAPG-COV-019 test kit membrane-based immunoassay alone, quantitative IgG test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Richmond Pharmacology Limited UK 2020-03-16 2020-08-31 C20010, NCT04404062 Phase Not Applicable No longer recruiting 1 5 Months 500 Jorg Taubel, MD 2020-05-28
COVIT-D: Increased Risk of Severe COVID-19 Infection in Patients With Vitamin D Deficiency Coronavirus disease 19 infection, Vitamin D deficiency Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Clinico San Carlos Spain 2020-04-17 2020-07-01 20/428-E_COVID, COVIT-D, NCT04403932 Phase Not Applicable Recruiting 1 2 Months 500 Fernando Macaya, Francisco J Martín, MD PhD 2020-05-29
A proof-of-concept clinical study to assess whether the Prototype Polygenic Risk Score would differentiate COVID-19 patients who required hospitalization from those who did not require hospitalization Coronavirus disease 19 infection Prototype Polygenic Risk Score alone Genetic Technologies Ltd Phase Not Applicable Status not specified 0 1500 2020-05-29
COVID-PSL: Observational Study in Diagnosed Patients COVID-19, Supported on an Outpatient Basis Coronavirus disease 19 infection telephone consultation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre de Recherches et d'Etude sur la Pathologie Tropicale et le Sida France 2020-06-15 2020-08-15 COVID-PSL, CREPATS 011, NCT04402905 Phase Not Applicable Not yet recruiting 1 2 Months 450 Christine Katlama, MD, Yasmine Dudoit 2020-05-29
IONIC: IMU-838 and Oseltamivir in treatment of Novel Coronavirus (COVID-19) Coronavirus disease 19 infection standard care alone, oseltamivir plus vidofludimus Dihydroorotate dehydrogenase inhibitor, Exo-alpha sialidase inhibitor, IL-17 antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospitals Coventry & Warwickshire NHS Trust UK 2020-05-15 2020-001805-21, IONIC, RA486120 Phase 2 Clinical Recruiting 1 120 Kavi Sharma 2020-05-29
Investigating the efficacy and safety of Niwasha mouthwash in controlling the symptoms of patients with COVID-19 Coronavirus disease 19 infection Niwasha mouthwash alone, routine treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Niwasha company Baqiyatallah University of Medical Sciences Iran 2020-05-25 IRCT20080901001165N59, ir.bmsu.rec.1399.021 Phase 3 Clinical Recruiting 1 80 Ali Ghazivini, Dr. Ghahreman, Mohammad Rezapour, Parisa Kianpour, Yunes Panahi 2020-05-29
Investigating the efficacy and safety of Plasmapheresis in patients with Moderate to severe COVID-19 Coronavirus disease 19 infection, Viral pneumonia Plasmapheresis alone, Routine treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bagheiat-allah University of Medical Sciences Iran 2020-04-29 IR.BMSU.REC.1399.119, IRCT20080901001165N58 Phase Not Applicable Recruiting 1 100 Behzad Einollahi, Gholamhosein Alishiri, Mohammad Rezapour, Parisa Kianpour, Yunes Panahi 2020-05-29
IgG/IgM Antibody Test in Patients Who Have Tested Negative or Positive for COVID-19 With Nasopharyngeal PCR Testing Coronavirus disease 19 infection SARS-Cov2 virus IgG/IgM Clungene rapid test cassette alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sharp HealthCare US 2020-05-05 2020-12-01 2005801, IGG/IGM COVID19, NCT04402814 Phase Not Applicable Recruiting 3 6 Months 60 Divina Fanning, RN, Fadi Haddad, MD, Kathryn Miller 2020-05-29
Pembrolizumab (CinnaGen Co, Iran) in COVID-19 Coronavirus disease 19 infection Standard of care alone, pembrolizumab, CinnaGen alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) CinnaGen Co Iran 2020-06-06 IR.SBMU.NRITLD.REC.1399.117, IRCT20150303021315N19 Phase 2 Clinical Not yet recruiting 2 62 Alireza Rezvani, Nasim Anjidani, Payam Tabarsi 2020-05-29
Endotoxin and circulating bacteriome in severe COVID-19 patients Coronavirus disease 19 infection, Sepsis, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chulalongkorn University Thailand 2020-03-13 TCTR20200527001 Phase Not Applicable Completed 1 19 Nattachai Srisawat 2020-05-29
Egyptian Doctors Stresses, Knowledge and Attitude During COVID-19 Pandemic Acute stress disorder, Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Ain Shams University Egypt 2020-05-31 2020-06-30 EGYPTIAN DOCTORS IN COVID-19, NCT04403581 Phase Not Applicable Not yet recruiting 1 1 Month 384 Riham H Raafat, MD 2020-05-29
Impact of COVID-19 on Personal Protection Among Dentist in Egypt Coronavirus disease 19 infection online survey alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Fayoum University, EG Egypt 2020-05-20 2020-06-15 NCT04403828, PPE IN COVID-19 Phase Not Applicable Recruiting 1 300 Aliaa I Mahroun, PhD, Aliaa I Mahrous, PhD, Alshaimaa A Shabaan, PhD, Alshaimaa Ahmed shabaan 2020-05-28
Convalescent Plasma Therapy in Severe COVID-19 Infection Coronavirus disease 19 infection, Respiratory distress syndrome antibiotic therapy alone, fluid therapy alone, steroid therapy alone, Variable regimens including apheretic convalescent plasma , enoxaparin sodium , favipiravir , lopinavir + ritonavir , oxygen , remdesivir COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, HIV protease inhibitor, Low molecular weight heparin, RNA polymerase inhibitor, RNA polymerase modulator Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bangabandhu Sheikh Mujib Medical University Dhaka medical college Bangladesh 2020-05-20 2020-10-30 BSMMU/2020/6104, NCT04403477 Phase 2 Clinical Recruiting 1 5 Months 20 Fazle R Chowdhury, FCPS, PhD, Fazle R Chowdhury, FCPS, PhD, Fazle Rabbi Chowdhury, Mohammad S Rahman, MPhil,FCPS, Mohammad S Rahman, MPhil, FCPS, Sayedur Rahman, MPhil, FCPS 2020-05-28
Covid-Immun: The role of immune-reactions in patients with COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Heidelberg Germany 2020-03-18 Covid-Immun, DRKS00021810, S-148/2020 Phase Not Applicable Recruiting 1 1000 Uta Merle 2020-05-29
Characterizing SARS-CoV-2-specific Immunity in Individuals Who Have Recovered From COVID-19 Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) HIV Vaccine Trials Network HIV Prevention Trials Network, National Institute of Allergy and Infectious Diseases US, Peru 2020-05-13 2021-08-31 5UM1AI068614-14, HVTN 405/HPTN 1901, NCT04403880 Phase Not Applicable Recruiting 27 15 Months 400 CRS Coodinator, CRS Coordinator, CRS Coorindator, CRS Leader, Clinical Trial Manager, E CRS Coordinator, Fernando Roman, Larry Corey, Protocol Team Leader, Shelly Karuna 2020-05-30
SOCRATES: Somerset and South Essex Coronavirus Antigen Testing Coronavirus disease 19 infection PCL COVID-19 Ag rapid FIA test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Somerset NHS Foundation Trust UK 2020-06-30 2021-08-31 IRAS283137, NCT04403906, SOCRATES Phase Not Applicable Not yet recruiting 1 14 Months 200 Caitlin Morgan, MBBS, Justin Pepperell, MD 2020-05-28
Convalescent plasma to limit COVID-19 associated complications Coronavirus disease 19 infection Convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Yale University Albert Einstein College of Medicine, NYU Langone Health 2020-05-31 2023-01-31 2000028181, NCT04404634 Phase 2 Clinical Not yet recruiting 0 32 Months 300 Alessandro Santin, MD, Mahalia Desruisseaux, MD 2020-05-29
Comparative assessment of the efficacy and safety of addon treatment with 'Sofosbuvir-Daclatasvir', 'Lithium',and 'Trifluoprazine' to 'standard of care' in three groups of patients with COVID-19 Coronavirus disease 19 infection hydroxychloroquine alone, Variable regimens including Sofosbuvir + Daclatasvir , hydroxychloroquine , lithium , trifluoperazine , trihexyphenidyl Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kermanshah University of Medical Sciences Iran 2020-04-08 IR.KUMS.REC.1399.063, IRCT20130812014333N147 Phase 3 Clinical Recruiting 1 80 Dr. Babak Sayad, Dr. Reza Khodarahmi, Feizollah Foroughi, habibolah khzaei 2020-05-28
DORNASESARS2: Dornase Alfa for ARDS in Patients With SARS-CoV-2 Coronavirus disease 19 infection, Lung injury, Respiratory distress syndrome, Respiratory failure dornase alfa alone, standard of care alone Deoxyribonuclease I stimulator, Deoxyribonuclease stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Missouri US 2020-05-30 2022-05-31 2022206, DORNASESARS2, NCT04402970 Phase 3 Clinical Not yet recruiting 1 24 Months 20 Mohammed Alnijoumi, MD, Zachary M Holliday, MD 2020-05-28
S3-study: Sero-surveillance SARS-CoV-2 Coronavirus disease 19 infection Serologic surveillance alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Amsterdam UMC Netherlands 2020-03-23 2020-12-31 NL8645, S3-study Phase Not Applicable Recruiting 1 9 Months 800 Jonne Sikkens 2020-05-28
COV-PLAS: A randomized, double blinded clinical trial of convalescent plasma compared to standard plasma for treatment of hospitalized non-ICU patients with COVID-19 infections Coronavirus disease 19 infection convalescent thawed fresh frozen plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Leiden University Medical Center Netherlands 2020-05-31 2021-05-01 COV-PLAS, NL8633 Phase 2/Phase 3 Clinical Recruiting 1 11 Months 430 Jaap Jan Zwaginga 2020-05-28
Ivermectin and Doxycycine in COVID-19 Treatment Coronavirus disease 19 infection doxycycline hyclate plus ivermectin (Iverzine) Tanta University Egypt 2020-06-01 2030-12-03 NCT04403555, TANTA COMBO COVID TREATMENT Phase 2/Phase 3 Clinical Not yet recruiting 1 126 Months 40 Sherief Abd-Elsalam, ass. prof., sherief Abd-Elsalam, Ass. Prof. 2020-05-28
The safety and efficacy of STC-3141 in patient with COVID-19 Acute Respiratory Distress Syndrome Adult respiratory distress syndrome, Coronavirus disease 19 infection STC-3141 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Grand Medical Pty Ltd Australia 2020-05-29 ACTRN12620000588998 Phase 2 Clinical Not yet recruiting 1 160 Dr Marcel Tanudji, Prof Anders Aneman 2020-05-28
Familial Mediterranean Fever and Behcet: Analysis Before and After COVID-19 Pandemic Behcets disease, Coronavirus disease 19 infection, Familial mediterranean fever Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Istanbul University Turkey 2020-04-01 2020-06-15 10840098-604.01.01-E.14697, NCT04403438 Phase Not Applicable Recruiting 1 2 Months 45 Nejla Uzun, MSc, Pt 2020-05-28
CoVEX: Different Susceptibility Among Health Care Workers Highly Exposed to Patients With COVID-19 Diagnosis Coronavirus disease 19 infection Flow cytometry alone, PCR test alone, RT-PCR test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Asociacion para el Estudio de las Enfermedades Infecciosas Spain 2020-06-01 2020-09-30 CoVEX, EC, NCT04402827 Phase Not Applicable Not yet recruiting 1 4 Months 50 Alejandro Vallejo, MD, PhD, Jose L Casado, MD, PhD 2020-05-29
Convalescent Plasma treatment trial in COVID 19 patients Coronavirus disease 19 infection Convalescent Plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Wockhardt Ltd India 2020-06-01 CTRI/2020/05/025299, WH-CP-02-21 Phase 2 Clinical Not yet recruiting 1 20 Dr AjayKumar R Yadav, Dr Ashima Bhatia, Dr Behram Shawak Pardiwalla 2020-05-28
Survey of Mouth-dissolving Turmeric Lozenges in Healthcare Workers Coronavirus disease 19 infection Trumgel alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Gelnova Laboratories (India) Pvt Ltd India 2020-05-26 CTRI/2020/05/025317 Phase 4 Clinical Not yet recruiting 1 300 DR MANJUSHA RAJARSHI, Dr Niharika Gill 2020-05-29
TRANSCOVID: Study of Viral Load and Maternal-fetal Serology in the Interpretation of the Vertical Transmission of SARS Cov-2 (COVID-19) During Pregnancy Coronavirus disease 19 infection nasopharyngeal aspiration alone, nasopharyngeal swab sampling alone, placenta swab sampling alone, serology alone, vaginal swab sampling alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital of Besancon France 2020-05-17 2020-12-31 2020/500, NCT04402918, TRANSCOVID Phase Not Applicable Recruiting 1 7 Months 160 Benazet Louis, MOTTET Nicolas, Dr 2020-05-29
LICCI: Trial of antihypertensive losartan for additional benefit in treating COVID 19 infection. Coronavirus disease 19 infection losartan alone, standard of care alone Angiotensin II AT-1 receptor antagonist, Angiotensin II receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sanjay Gandhi Postgraduate Institute of Medical Sciences India 2020-06-01 CTRI/2020/05/025319, LICCI Phase 3 Clinical Not yet recruiting 1 186 Dr Able Lawrence 2020-05-29
Etiology of Lymphopenia in Covid-19 Infection Coronavirus disease 19 infection, Lymphocytopenia blood sampling alone, bone marrow aspiration cytology alone Cairo University Egypt 2020-06-30 2021-12-31 201920008.2, NCT04404608 Phase Not Applicable Not yet recruiting 1 18 Months 90 Dr Medhat Khafagy 2020-05-29
YONAC: Effect of Yoga & Naturopathy in patients with COVID-19 Coronavirus disease 19 infection Yoga & Naturopathy immune boostinng and stress management protocol alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Government Yoga And Naturopathy Medical College Indian Naturopathy And Yoga Graduates Medical Associatio India 2020-05-22 CTRI/2020/05/025320, YONAC Phase 3 Clinical Recruiting 4 658 Manavalan Narayanaswamy 2020-05-29
Comparison of the ID NOW and Accula Point-of-Care Assays for Detection of COVID-19 Coronavirus disease 19 infection Accula (Mesa Biotech) alone, ID Now (Abbott) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ascension South East Michigan US 2020-05-10 2021-05-09 1599159, NCT04403035 Phase Not Applicable Recruiting 1 12 Months 100 Leonard B Johnson, MD, Leonard B. Johnson, MD, Melphine Harriott, PhD 2020-05-29
The Hope Coalition - 1: Hydroxychloroquine and Lopinavir + Ritonavir to Improve the Health of People With COVID-19 Coronavirus disease 19 infection, Respiratory disease hydroxychloroquine alone, lopinavir + ritonavir alone, hydroxychloroquine plus lopinavir + ritonavir HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cardresearch - Cardiologia Assistencial e de Pesquisa LTDA Cytel Inc Brazil 2020-05-28 2020-11-28 COVID19-AMB-BRASIL, NCT04403100, The Hope Coalition - 1 Phase 3 Clinical Not yet recruiting 4 6 Months 1968 Daniela Silva, MD, PhD, Eduardo Silva, MD, PhD, Gilmar Reis, MD, PhD, Gilmar Reis, MD,PhD, Izabel Silva, SC, Leonardo Savassi, MD, PhD, Rosemary Oliveira, SC 2020-05-29
PH-94B in the Treatment of Adjustment Disorder With Anxiety Adjustment disorder, Anxiety disorder, Coronavirus disease 19 infection PH-94B alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) VistaGen Therapeutics Inc US 2020-11-30 2021-09-30 COVID19_IMPACT, NCT04404192, PH94B-CL-029 Phase 2a Clinical Not yet recruiting 1 10 Months 30 Ann Draine, Matt Turzilli, Michael Liebowitz, MD 2020-05-29
Tablet PINAK given as treatment to COVID positive patients Coronavirus disease 19 infection PINAK alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shree Bharadi Ayurvedic Pharamaceuticals India 2020-05-31 CTRI/2020/05/025326 Phase 2 Clinical Not yet recruiting 1 30 Dr Pandurang Pawar, Shreepad Bhat 2020-05-29
PedCan-COVID: Extraordinary Measures for Egyptian Children With Hemato-Oncological Disorders During COVID-19 Pandemic Coronavirus disease 19 infection, Hematological disease, Hematological neoplasm, Respiratory disease, Solid tumor chest x-ray alone, computed chest tomography alone, reverse transcription polymerase chain reaction test alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Ain Shams University Egypt 2020-01-01 2021-06-01 FMASU P25A/ 2020, NCT04404244, PedCan-COVID Phase Not Applicable Recruiting 1 17 Months 100 Fatma Ebeid, Fatma Soliman E Ebeid 2020-05-28
To study some blood tests which would help predict severity and outcome in children with cancers having the novel corona virus infection Coronavirus disease 19 infection Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) Christian Medical College, Vellore, India India 2020-06-09 CTRI/2020/05/025327 Phase Not Applicable Not yet recruiting 1 60 Deepthi Boddu 2020-05-29
COLORIT: Colchicine Versus Ruxolitinib and Secukinumab In Open, Prospective, Randomized Trial Coronavirus disease 19 infection, Viral pneumonia colchicine alone, ruxolitinib alone, secukinumab alone IL-17 antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) MV Lomonosov Moscow State University Russian Federation 2020-05-08 2020-08-23 COLORIT, MSU080520, NCT04403243 Phase 2 Clinical Recruiting 1 3 Months 70 Julia Begrambekova, Phd, Julia Leonovna Begrambekova, Phd, Yana Orlova, Professor 2020-05-29
TOCIBRAS: Safety and Efficacy of Tocilizumab in Moderate to Severe COVID-19 With Inflammatory Markers Coronavirus disease 19 infection Best supportive care alone, tocilizumab (intravenous), Roche/Chugai alone, tocilizumab (subcutaneous), Roche/Chugai alone IL-6 receptor antagonist, IL-6 receptor modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Beneficencia Portuguesa of Sao Paulo Brazilian Clinical Research Institute, Brazilian Research In Intensive Care Network, Hospital Alemao Oswaldo Cruz, Hospital do Coracao, Instituto de Educação e Pesquisa do Hospital Moinhos de Vento, Sociedade Beneficente Israelita Brasileira Hospital Albert Einsten, Sociedade Beneficiente De Senhoras Hospital Sirio Libanes Brazil 2020-05-08 2020-08-31 NCT04403685, TOCIBRAS, TOCIBRAS Phase 3 Clinical Recruiting 7 3 Months 150 Alexandre Biasi Cavalcanti, MD, Danielle Leao Cordeiro de Farias, MD, Danielle Leão Cordeiro de Farias, MD, Flavia R Machado, Joao Prats, MD, Luciano Azevedo, Phillip Scheinberg, MD, Viviane C Veiga, MD, Viviane Veiga, MD 2020-05-29
The Acai Berry COVID-19 Anti-inflammation Trial Coronavirus disease 19 infection acai palm berry extract (Nature's Way) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The University Health Network University of Toronto Canada 2020-05-31 2021-05-31 CTO3176, NCT04404218 Phase 2 Clinical Not yet recruiting 2 12 Months 480 Ana Andreazza, PhD, Hassan Ellaban, Michael Farkouh, MD, MSc 2020-05-29
TaCOVID: Tannin Specific Natural Extract for COVID-19 Infection Coronavirus disease 19 infection antibiotic therapy alone, antipyretics therapy alone, non-invasive ventilation alone, supplemental oxygen therapy alone, Variable regimens including ARBOX , azithromycin , hydroxychloroquine , lopinavir + ritonavir HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Jose de San Martin Hospital de Clinicas SILVATEAM Argentina 2020-06-01 2020-10-31 HCJSM-20-005, NCT04403646, TaCOVID Phase 2 Clinical Not yet recruiting 1 5 Months 140 Maria M Piskorz, MD, Maria Marta Piskorz, MD 2020-05-28
COVID PLASMA: Study to Assess the Safety and Efficacy of Convalescent Plasma on outcome of COVID-19 Associated Complications Coronavirus disease 19 infection convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Indraprastha Apollo Hospitals India 2020-06-01 COVID PLASMA, CTRI/2020/05/025328, Protocol No. Covid 19, Version no 1.1 Phase 2 Clinical Not yet recruiting 5 100 Dr D Suresh Kumar, Dr Rajesh Chawla, Dr Suneetha Narreddy, Dr Suresh Ramasubban, Dr Tushar Parmar 2020-05-28
CISCO-19: Cardiac Imaging in SARS-CoV-2 (COVID-19) Coronavirus disease 19 infection, Heart injury, Myocarditis, Pulmonary heart disease MRI alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) NHS Greater Glasgow and Clyde University of Glasgow UK 2020-05-22 2021-08-31 CISCO-19, GN20ID164, NCT04403607 Phase Not Applicable Recruiting 3 15 Months 180 Colin Berry, MBChB/PhD, Douglas Grieve, MBChB/PhD, Hannah Bayes, MBChB/PhD, Kenneth Mangion, MBChB/PhD, Kevin Blyth, MBChB/PhD, Lynsey Gillespie, PhD 2020-05-28
Performance Evaluation of RealDetect COVID-19 RT-PCR Kit for the Detection of SARS-CoV-2 Virus Coronavirus disease 19 infection RealDetect COVID-19 RT-PCR kit alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Bangladesh Medical Research Council (BMRC) Bangladesh 2020-05-18 2020-07-24 30005052020, NCT04403672 Phase Not Applicable Recruiting 1 2 Months 120 Rosy Sultana, MBBS, MPhil, Zahid Hassan, MBBS, PhD 2020-05-29
SR4COVID: Protect and prevent onset of COVID like infections in Health Care Workers and High risk person Coronavirus disease 19 infection REIMMUGEN plus SUVED Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Health Solutions, India India 2020-05-30 CTRI/2020/05/025334, SR4COVID Phase 2 Clinical Not yet recruiting 1 30 Shreepad Bhat, Sujata Vaidya 2020-05-28
The Clinical Difference Between the Nonfatal Patients and the Fatal Patients With Severe COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The First Affiliated Hospital of Guangzhou Medical College China 2020-02-01 2020-06-20 NCT04403009, YLS2020(112) Phase Not Applicable Recruiting 2 4 Months 100 jianheng zhang, MD 2020-05-28
PRE-VENT: Phase III Study in Hospitalized Patients With Severe COVID-19 With or Without Cancer Coronavirus disease 19 infection pacritinib alone, standard of care alone CSF-1 antagonist, Cytochrome P450 reductase inhibitor, Flt3 tyrosine kinase inhibitor, IRAK-1 protein kinase inhibitor, Jak2 tyrosine kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) CTI BioPharma Corp US 2020-05-22 2021-10-31 NCT04404361, PAC319, PRE-VENT Phase 3 Clinical Not yet recruiting 1 17 Months 358 John Mascarenhas 2020-05-28
A biomarker study to assess the correlation between LIGHT levels and disease severity and mortality in a COVID-19 acute respiratory distress syndrome (ARDS) Coronavirus disease 19 infection, Respiratory distress syndrome Healthy volunteers accepted Cerecor Inc, Myriad Genetics Inc Phase Not Applicable Status not specified 0 77 2020-05-28
EpiCovCreil: Study of SARS-CoV2 Virus (COVID-19) Seroprevalence in the Population of Creil Air Force Base (BA110) Coronavirus disease 19 infection Anti-SARS-CoV2 serology test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Direction Centrale du Service de Sante des Armees France 2020-05-31 2021-02-28 2020-COVID19-22, EpiCovCreil, NCT04404270 Phase Not Applicable Not yet recruiting 1 9 Months 2500 Anaïs GROSSET-JANIN, MD, Sandrine DURON, MD, PhD 2020-05-29
SARS Cov-2 in Conjunctival Secretion Coronavirus disease 19 infection, Viral pneumonia rtPCR alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Università degli Studi dell'Insubria Italy 2020-02-01 2020-05-20 72/2020, NCT04402853 Phase Not Applicable Completed 1 3 Months 100 Simone Donati, Professor 2020-05-29
SARS-CoV-2 Saliva Coronavirus disease 19 infection Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Hospital Sungai Buloh Ministry of Health, Malaysia Malaysia 2020-05-18 2020-08-17 NMRR-20-902-54894 Phase Not Applicable Not yet recruiting 1 3 Months 12 Dr Denisa Khoo Fern Ying, Dr Kalaiarasu Peariasamy 2020-05-29
Rapid antigen detection for SARS-CoV-2 Coronavirus disease 19 infection rapid antigen detection test alone National Institutes of Health Malaysia Ministry of Health, Malaysia Malaysia 2020-06-01 2022-02-28 54859, NMRR-20-944-54859 Phase Not Applicable Status not specified 1 21 Months Dr Norazah binti Ahmad, Ms Jamaayah Bt Mohamed Zahidi @ Ahmad Bakri 2020-05-29
HCW-COVID Coronavirus disease 19 infection HOSPITAL RAJA PEREMPUAN ZAINAB II Malaysia 2020-06-01 2021-06-01 55011, NMRR-20-952-55011 Phase Not Applicable Status not specified 1 12 Months 2000 Dr Diana Foo Hui Ping, Dr LEE HUEY CHUN 2020-05-29
Generation of immune Fab phage display library against a novel coronavirus (2019-nCoV) Coronavirus disease 19 infection Universiti Sains Malaysia Malaysia 2020-02-20 2020-12-31 34314, NMRR-17-3569-34314 Phase Not Applicable Status not specified 1 10 Months Dr Jeyanthi a/p Suppiah, Dr. Mohammad Ridhuan Bin Mohd Ali 2020-05-29
Detailed Organ System Analysis of Asymptomatic COVID19 patients using noninvasive mobile tool Coronavirus disease 19 infection Lyfas Mobile tool alone Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Acculi Labs India 2020-06-05 CTRI/2020/05/025345 Phase Not Applicable Not yet recruiting 1 100 Dr Pooja Sharma, Dr Sushila Kataria, Rishikesh Ranjan 2020-05-29
LSALT Peptide versus Placebo to Prevent ARDS and Other Organ Injuries in Patients Infected With SARS-CoV-2 (COVID-19) Blood clotting disorder, Coronavirus disease 19 infection, Liver injury, Lung inflammation, Myocardial disease, Nephritis, Renal injury, Respiratory distress syndrome Metablok alone, standard of care alone Dehydropeptidase-1 modulator Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Arch Biopartners Inc Canada 2020-07-01 2021-06-30 AB002, NCT04402957 Phase 2 Clinical Not yet recruiting 1 12 Months 60 Daniel A Muruve, MD, Richard Muruve 2020-05-29
Pulmozyme to Improve COVID-19 ARDS Outcomes Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure, Viral pneumonia dornase alfa alone, standard of care alone Deoxyribonuclease I stimulator, Deoxyribonuclease stimulator Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Boston Children's Hospital Brigham & Women's Hospital US 2020-05-25 2021-12-31 NCT04402944, P00035140 Phase 2 Clinical Not yet recruiting 1 19 Months 60 Benjamiin Raby, Robert Fowler 2020-05-29
A Clinical Trial to Assess the Safety and Efficacy of Convalescent Plasma in Severe COVID-19 patients Coronavirus disease 19 infection convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Government of Tamil Nadu India 2020-06-01 CTRI/2020/05/025346, Form CT-06, No. CT/BP/07/2020 Phase 2 Clinical Not yet recruiting 1 90 Dr Latha B, Dr S Anbuselvi Mattuvar Kuzhali, DrJAYANTHI RANGARAJAN 2020-05-28
Resistir: Th1/Th2/Th17/TREG and TLRs Activation/KIR for COVID-19 Prediction of Outcome Coronavirus disease 19 infection RT-PCR alone, flow cytometry alone, plasma sampling alone, polymerase chain reaction alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Asociacion para el Estudio de las Enfermedades Infecciosas Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal Spain 2020-05-22 2020-09-30 EC128/20, NCT04403061, Resistir Phase Not Applicable Recruiting 1 4 Months 80 Alejandro Vallejo, MD, PhD, Ana Moreno, MD, PhD, Carmen Quereda, MD, PhD, Jose L Casado, Md, PhD, Jose M Del Rey, MD, PhD, Pilar Vizcarra, MD 2020-05-29
'Increasing Physical Activity in Canadian Adults Who Have Been Affected by COVID-19 Social Distancing Restrictions: A Feasibility Trial of an Online Intervention' (COVID-19) Coronavirus disease 19 infection Digital Health Online Platform alone, baseline questionnaire alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Victoria Canada 2020-05-20 2020-09-30 05-281983, NCT04400305 Phase Not Applicable Recruiting 1 4 Months 40 Ryan Rhodes, Sandy L Courtnall, Stina Grant 2020-05-29
Prospective, Natural History Study of Smoking, Immune Cell Profiles, Epigenetics and COVID-19 Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) National Institute Of Environmental Health Sciences National Institutes of Health Clinical Center US 2020-06-02 2022-05-31 20-E-0108, 200108, NCT04403386 Phase Not Applicable Not yet recruiting 2 23 Months 200 Nicole Edwards, Stavros Garantziotis, M.D. 2020-05-29
Study to assess safety and efficacy of Inj Sepsivac in patients of COVID-19 Coronavirus disease 19 infection Sepsivac alone, standard therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) RD Gardi Medical College India 2020-05-31 CTRI/2020/05/025350 Phase 2 Clinical Not yet recruiting 1 50 Dr Ashish Pathak 2020-05-29
QTW2020: COVID-19 Brief Advice and Chat-based Support for Smoking Cessation Via 'Quit to Win' Contest 2020 Coronavirus disease 19 infection, Nicotine dependence AWARD advice alone, COSH booklet alone, COVID-19 specific advice alone, COVID-related health warning leaflet alone, Personalized instant messaging alone, referral card alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The University of Hong Kong Hong Kong Council on Smoking and Health Hong Kong 2020-06-13 2022-06-30 NCT04399967, QTW 2020, QTW2020 Phase Not Applicable Not yet recruiting 1 24 Months 842 Man Ping Kelvin Wang, PhD, Xue Weng, PhD 2020-05-29
FAITH: A Phase III study of Favipiravir and Umifenovir in hospitalized patients of moderate COVID-19 in India Coronavirus disease 19 infection standard supportive care alone, favipiravir plus umifenovir RNA polymerase inhibitor Glenmark Pharmaceuticals Ltd India FAITH Phase 3 Clinical Planned 1 158 2020-05-28
A Study of APL-9 in Adults With Mild to Moderate ARDS Due to COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure APL-9 alone, standard of care alone Complement C3 modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Apellis Pharmaceuticals Inc US 2020-05-26 2020-11-30 APL9-COV-201, NCT04402060 Phase 1/Phase 2 Clinical Not yet recruiting 4 6 Months 66 Apellis Clinical Trial Information Line 2020-05-29
CACOLAC: Citrulline Administration in the Hospital Patient in Intensive Care for COVID-19 Acute Respiratory Distress Syndrome Coronavirus disease 19 infection, Lung disease, Respiratory distress syndrome, Viral pneumonia L-citrulline alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rennes University Hospital France 2020-06-15 2021-07-15 2020-A01189-30, 35RC20_9815_CACOLAC, CACOLAC, CPP 1288 HPS1, NCT04404426 Phase Not Applicable Not yet recruiting 5 13 Months 100 Agathe Delbove, MD, Aurélien Frerou, MD, Erwan L'Her, MD, Florian Reizine, MD, Jean-Marc Tadié, MD, Pierre Asfar, MD 2020-05-29
IVERCOVID: Does ivermectin cure and/or prevent COVID-19? Coronavirus disease 19 infection Lagos State University Teaching Hospital Nigeria 2020-04-23 2020-06-23 ISRCTN40302986, IVERCOVID Phase Not Applicable Recruiting 2 2 Months Prof Babalola 2020-05-29
StudentCov: Psychological Impact of the Covid-19 Pandemic on Student Nurses Coronavirus disease 19 infection, Post traumatic stress disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Hospital, Versailles France 2020-05-12 2020-07-31 NCT04402229, P17/04_STUDENTCOV, StudentCov Phase Not Applicable Recruiting 2 2 Months 2000 Guillaume Decormeille, RN, MSc, Gwenaelle Jacq, RN, Jacq Gwenaelle, Stephane Legriel, MD, PhD 2020-05-29
Real-World Antiviral Therapy In COVID-19 Coronavirus disease 19 infection antiviral therapy alone Hospital Universiti Sains Malaysia Malaysia 2020-05-20 2021-08-31 54911, NMRR-20-1006-54911 Phase 4 Clinical Not yet recruiting 4 15 Months Dr Lee Yeong Yeh, SITI NORIZAN BINTI ABDUL RANI 2020-05-29
COVID-19 Seroprevalence in RRT patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Malaya Medical Centre Malaysia 2020-06-01 2020-12-31 54927, NMRR-20-997-54927 Phase Not Applicable Not yet recruiting 2 7 Months 650 Dr Rosnawati Yahya, LIM SOO KUN 2020-05-29
Efficacy of AYUSH-64 (a polyherbal formulation) in COVID - 19 Cases Coronavirus disease 19 infection AYUSH-64 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Central Council for Research in Ayurvedic Sciences India 2020-05-31 CTRI/2020/05/025335 Phase 3 Clinical Not yet recruiting 1 40 Dr N R Singh, Dr Vidula Gujjarwar 2020-05-29
Randomized Controlled Trial Of Resveretrol-Copper Or Sodium-Copper-Chlorophyllin Vs Standard Treatment In Mild Covid-19 infection Coronavirus disease 19 infection Resveratrol- Copper alone, antibacterial therapy alone, antibiotic therapy alone, antimicrobial therapy alone, antiviral therapy alone, sodium-copper-chlorophyllin alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tata Memorial Centre India 2020-06-01 CTRI/2020/05/025336 Phase 3 Clinical Not yet recruiting 1 Indraneel Mittra, Vikram Gota 2020-05-29
Randomized Controlled Trial Of Resveretrol-Copper OR Sodium-Copper-Chlorophyllin Versus Standard Treatment In Severe Covid-19 Coronavirus disease 19 infection Resveratrol- Copper alone, antibacterial therapy alone, antibiotic therapy alone, antimicrobial therapy alone, antiviral therapy alone, sodium-copper-chlorophyllin alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tata Memorial Centre India 2020-06-01 CTRI/2020/05/025337 Phase 2 Clinical Not yet recruiting 1 200 Indraneel Mittra, Vikram Gota 2020-05-29
Predictive Models for Intensive Care Admission and Death of COVID-19 Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), African Ancestry, European Ancestry Cliniques Saint-Pierre Ottignies Belgium 2020-03-01 2021-01-01 0410508057, NCT04401228 Phase Not Applicable No longer recruiting 1 10 Months 60 Nicolas Parisi 2020-05-29
COLIDE: COVID-19: Laser Interferometry for Rapid Single Coronavirus Detection Coronavirus disease 19 infection laser interferometry test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Somerset NHS Foundation Trust Exeter University, University of Plymouth UK 2020-06-30 2021-12-31 COLIDE, NCT04401644, RBA20203 Phase Not Applicable Not yet recruiting 1 18 Months 250 Flora Darch, Karen Tanner 2020-05-29
Evaluation of Efficacy and Safety of Ayurveda Intervention (Ayush -64) in the management of COVID-19 infection (Asymptomatic &Mild to Moderate symptoms Coronavirus disease 19 infection Ayush 64 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Council for Research in Ayurvedic Sciences India 2020-06-02 CTRI/2020/05/025338 Phase 2/Phase 3 Clinical Not yet recruiting 1 40 Dr BabitaYadav, Dr Manoj Shamkuwar, Dr Shivshankar Rajput 2020-05-29
Prevalence and Severity of Venous Thromboembolism in a General Population During the COVID-19 Pandemic Coronavirus disease 19 infection, Deep vein thrombosis, Lung embolism CT pulmonary angiogram alone, ultrasound alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Linkoeping Sweden 2020-06-01 2020-06-30 NCT04400877, SE2020-02701 Phase Not Applicable Not yet recruiting 1 1 Month 12000 Daniel Wilhelms, Daniel Wilhelms, PhD, Jens Wretborn, MD, Joakim Henricson, PhD, Matthias Jörg, MD, Patrik Benjaminsson Nyberg, PhD 2020-05-29
Treatment and economical problems faced due to non COVID patients admitted in severe acute respiratory illness (SARI) ICU based on SARI criteria Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kasturba Medical College and Hospital India 2020-06-02 COVID_IMPACT, CTRI/2020/05/025339 Phase Not Applicable Not yet recruiting 2 500 Dr Sumalatha A, Dr Sunil R 2020-05-29
Controlled and randomized trial to assess the safety and efficacy of hydroxychloroquine chemoprophylaxis in SARS CoV2 infection in hospital healthcare personnel (Sanitarios sin COVID-19) Coronavirus disease 19 infection, SARS coronavirus infection Hydroxychloroquine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Fundacion Instituto de Investigacion Marques de Valdecilla, IDIVAL Spain 2020-05-15 2020-001704-42, SANsinCOVID Phase 4 Clinical No longer recruiting 1 450 Mar García Sáiz 2020-05-29
Clinical trial of ShatPlus in SARS-CoV-2 Infection Coronavirus disease 19 infection ShatPlus alone, Standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) BVG Life Sciences Ltd India 2020-06-01 CTRI/2020/05/025340, PROTOCOL NO- MHC/CT/20-21/001 Phase 1/Phase 2 Clinical Not yet recruiting 1 60 Dr Patsute Sudhir Dadaram, Dr Pawan Kumar Singh 2020-05-29
Study on Safety and Efficacy of Favipiravir (Favipira) for COVID-19 Patient in Selected Hospitals of Bangladesh Coronavirus disease 19 infection favipiravir alone, standard treatment alone RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Bangladesh Medical Research Council (BMRC) Bangladesh 2020-05-31 2020-07-31 29318042020, NCT04402203 Phase 2/Phase 3 Clinical Recruiting 1 2 Months 50 Ahmedul Kabir, MBBS, FCPS FACP, FRCP, Ahmedul Kabir, MBBS, FCPS, FACP, FRCP, Md. Billal Alam, MBBS, FCPS MD, MACP, FACP 2020-05-29
CALYPSO: COVID-19 Associated Lymphopenia Pathogenesis Study in Blood Coronavirus disease 19 infection, Lymphocytopenia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Allergy and Infectious Diseases National Institutes of Health Clinical Center US 2020-05-22 2022-06-30 20-I-0111, 200111, CALYPSO, NCT04401436 Phase Not Applicable Recruiting 2 25 Months 165 Irini Sereti, M.D., Princy Kumar, M.D. 2020-05-29
A study to know the effect of Ayurvedic Kwath(Kiratiktadi Kwath) and Ashwagandha Churna along with yoga exercises in the treatment of COVID-19 Positive patients Coronavirus disease 19 infection Variable regimens including Ashwagandha churna , Kiratiktadi Kwath Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) GS Ayurveda Medical College & Hospital India 2020-06-02 CTRI/2020/05/025341 Phase Not Applicable Not yet recruiting 1 30 Ankur Singhal 2020-05-29
Efficacy of vitamin D treatment in patients diagnosed with pneumonia who require hospital admission and have vitamin D deficiency and a positive diagnosis for SARS-Cov-2 (COVID-19) Coronavirus disease 19 infection, Viral pneumonia, Vitamin D deficiency Hidroferol alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Investigation Institute Bioaraba Spain 2020-05-25 2020-001960-28, RCTVITD/SARS-CoV-19 Phase 4 Clinical Recruiting 1 108 Inés Pérez Francisco 2020-05-29
Nigella Sativa in COVID-19 Coronavirus disease 19 infection, Upper respiratory tract infection Nigella sativa seed oil alone, standard care protocol alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) King Abdulaziz University Saudi Arabia 2020-05-21 2020-12-31 266-20, NCT04401202 Phase 2 Clinical Recruiting 1 7 Months 200 Abdulrahman Koshak, Dr, Dr Abdulrahman E. Koshak 2020-05-29
SARSCoV2CZPrev: COVID-19: Herd Immunity Study in the Czech Republic Coronavirus disease 19 infection Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institute of health information and statistics of the Czech Republic Central Military Hospital, Prague, Charles University, Czech Academy of Sciences, Czech Statistical Office, Faculty Hospital Olomouc, General University Hospital, Prague, Institut Klinické a Experimentální Medicin, Krajská zdravotní, a.s., Ústí nad Labem Region Hospitals, MasaryKuv Onkologicky Ustav, Masaryk University, Ministry of Health, Czech Republic, Palacky University, University Hospital Brno, University of Defence in Brno, University of Ostrava, Univerzita Jana Evangelisty Purkyne Prirodovedecka Fakulta Czech Republic 2020-04-23 2020-05-01 NCT04401085, SARSCoV2CZPrev, UZIS 2020/1 Phase Not Applicable Completed 1 27000 Ladislav Dušek, Prof., Marián Hajdúch, Assoc. Prof., Rastislav Maďar, Assoc. Prof., Roman Chlíbek, Prof. 2020-05-29
Multicenter, randomized, open-label study to evaluate the efficacy and safety of SOC + sarilumab versus standard of care for the early treatment of COVID-19-pneumonia in hospitalized patients Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia sarilumab alone, standard of care alone IL-6 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidad Autonoma de Madrid SANOFI-AVENTIS, S.A Spain 2020-05-25 2020-002037-15, SARTRE Phase 2 Clinical Recruiting 1 200 Belen Ruiz Antorán 2020-05-29
ACTIVATE II: BCG Vaccination to Prevent COVID-19 Coronavirus disease 19 infection BCG vaccine (Serum Institute of India Pvt. Ltd) alone Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hellenic Institute for the Study of Sepsis Greece 2020-05-26 2020-002448-21, ACTIVATE II, ACTIVATEII Phase 4 Clinical Recruiting 1 900 President of the Board 2020-05-29
Using GM-CSF as a Host Directed Therapeutic Against COVID-19 Coronavirus disease 19 infection, Hypoxia, Respiratory failure, Viral pneumonia sargramostim alone, standard of care alone CSF-1 agonist, GM-CSF receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Singapore General Hospital Pte Ltd Singapore 2020-06-30 2022-06-30 NCT04400929, SH-LEUK-01 Phase 2 Clinical Not yet recruiting 1 24 Months 30 Jenny Low, MBBS 2020-05-29
Colchicine for the Treatment of Hyperinflammation Associated with Pneumonia due to COVID-19 Coronavirus disease 19 infection, Inflammatory disease, Viral pneumonia colchicine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Spanish Society of Cardiology Spain 2020-05-25 2020-001841-38, Col-VID Phase 3 Clinical Recruiting 1 240 Alberto Cecconi 2020-05-29
Impact of remote audio-visual surveillance of doffing process during COVID 19 pandemic on the safety of health care workers Coronavirus disease 19 infection remote audio-visual surveillance alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Postgraduate Institute of Medical Education and Research India 2020-05-30 CTRI/2020/05/025274 Phase Not Applicable Not yet recruiting 1 100 AJAY SINGH 2020-05-29
Role of Chyawanprash in the prevention of COVID-19 in health care workers Coronavirus disease 19 infection Chyawanprash alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Central Council for Research in Ayurveda and Siddha India 2020-05-30 CTRI/2020/05/025275 Phase 3 Clinical Not yet recruiting 1 200 Dr Arun Gupta, Prof Dr Vidula Gujjarwar 2020-05-29
Effect of Ayurvedic intervention in COVID-19 positive cases Coronavirus disease 19 infection Variable regimens including Amalaki Churna , Golden Milk , Nagaradi kwath , Sanshamani Vati Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Chaudhary Brahm Prakash Ayurved Charak Sansthan India 2020-05-29 CTRI/2020/05/025276 Phase 3 Clinical Not yet recruiting 1 50 Dr Arun Gupta, ProfDr Vidula Gujjarwar 2020-05-29
Attitude of Egyptian Population Toward COVID-19 in Ramadan Coronavirus disease 19 infection Healthy volunteers accepted Damanhour University Egypt 2020-04-24 2020-10-31 COVID 19 IN RAMADAN, NCT04401072 Phase Not Applicable Recruiting 1 6 Months 500 Amira Kassem, PHD, Amira kassem, PHD, Noha El bassiouny, PHD, Noha el bassiouny, PHD 2020-05-28
DECORE: Increased Risk of SARS-CoronaVirus-2 (SARS-CoV-2) Infection Associated With Endoscopy Coronavirus disease 19 infection abdominal ultrasound alone, gastrointestinal endoscopy alone, telephonic medical visit alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Hospital del Río Hortega Spain 2020-05-11 2020-06-30 003, DECORE, NCT04401033 Phase Not Applicable Recruiting 1 1 Month 450 Manuel Pérez-Miranda Castillo, MD PhD, Marina De Benito, MD, Marina de Benito Sanz, Marina de Benito Sanz, MD 2020-05-28
SU-REM-COVID: Study results of Ayurvedic treatment on COVID patients using proprietary herbal formulation SUVED and whole colostrum REIMMUGEN Coronavirus disease 19 infection REIMMUGEN plus SUVED Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Health Solutions, India India 2020-05-30 CTRI/2020/05/025343, SU-REM-COVID Phase 2/Phase 3 Clinical Not yet recruiting 1 30 Shreepad Bhat, Sujata Vaidya 2020-05-28
SARS-CoV-2 in Malaysia Coronavirus disease 19 infection Institute For Medical Research (Inc In Malaysia), University of Malaya Malaysia 2020-03-17 54197, NMRR-20-536-54197 Phase Not Applicable Not yet recruiting 2 3000 Dr Norazah binti Ahmad, Professor Dr Jamal I-Ching Sam 2020-05-28
A multicenter registry analysis on the use of hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19 Coronavirus disease 19 infection chloroquine alone, hydroxychloroquine alone, Variable regimens including chloroquine , hydroxychloroquine , macrolide Brigham & Women's Hospital US Phase Not Applicable Status not specified 1 96032 2020-05-28
A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of EB05 + SOC versus Placebo + SOC in Adult Hospitalized Patients With Moderate to Severe COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia EB-05 alone, standard of care alone TLR-4 antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Edesa Biotech Inc JSS Medical Research Inc 2020-07-31 2020-10-31 EB05-01-2020, NCT04401475 Phase 2 Clinical Not yet recruiting 0 3 Months 510 Blair Gordon, PhD 2020-05-28
BAT IT: Anti-SARS Cov-2 T Cell Infusions for COVID-19 Coronavirus disease 19 infection anti-SARS Cov-2 T Cell alone, Tylenol plus cetirizine Histamine H1 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Baylor College of Medicine AlloVir, Center for Cell and Gene Therapy, Houston Methodist US 2020-07-30 2021-08-15 BAT IT, H-47739 BAT IT, NCT04401410 Phase 1 Clinical Not yet recruiting 1 12 Months 20 Premal Lulla, Premal Lulla, MD 2020-05-27
CO-Qo-ICU: One-year Outcomes in Survivors of the Severe COVID-19 Pneumonia Coronavirus disease 19 infection, Hypoxia, Respiratory distress syndrome, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire De Nice France 2020-06-16 2021-06-15 20REAMEDCOVID04, CO-Qo-ICU, NCT04401111 Phase Not Applicable Not yet recruiting 1 12 Months 150 Clément SACCHERI, Jean DELLAMONICA, Jean DELLAMONICA, MD, PhD 2020-05-27
LOVIT-COVID: Lessening Organ Dysfunction With Vitamin C - COVID-19 Coronavirus disease 19 infection vitamin C alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universite de Sherbrooke Lotte & John Hecht Memorial Foundation Canada 2020-06-30 2022-01-31 LOVIT-COVID, MP-31-2021-3741, NCT04401150 Phase 3 Clinical Not yet recruiting 1 19 Months 800 François Lamontagne, MD, FRCPC, MSc, Julie Menard, PhD, Marie-Helene Masse, Neill K Adhikari, MDCM, FRCPC, MSc 2020-05-28
COVID-Recovery: Recovery of Patients From COVID-19 After Critical Illness Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Australian and New Zealand Intensive Care Research Centre The Alfred (AU) Australia 2020-05-31 2022-04-30 COVID-RECOVERY V1.0 01MAY2020, COVID-Recovery, NCT04401254 Phase Not Applicable Not yet recruiting 7 23 Months 300 Carol Hodgson, PhD, Natalie Linke, RN 2020-05-27
Cardiac Manifestation of Covid-19 Patients in Children Coronavirus disease 19 infection, Kawasaki disease echocardiography alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Universiti Putra Malaysia Malaysia 2020-05-22 2020-05-30 55099, NMRR-20-1018-55099 Phase Not Applicable Not yet recruiting 1 7 dr putri bt yubbu 2020-05-27
Treatment of Lung Injury From COVID-19 Infection With Intravenous Sodium Nitrite Coronavirus disease 19 infection, Lung injury, Respiratory failure sodium nitrite (intravenous, sickle cell disease/myocardial infarction/cerebral vasospasm), Hope Pharmaceuticals alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hope Pharmaceuticals Inc 2020-06-30 2020-12-31 NCT04401527, SN02-01 Phase 2 Clinical Not yet recruiting 0 6 Months 200 Hope Pharmaceuticals Medical Director 2020-05-28
NGS SARS-CoV-2 Coronavirus disease 19 infection National Institutes of Health Malaysia Malaysia 2020-05-18 2021-12-31 54816, NMRR-20-884-54816 Phase Not Applicable Status not specified 1 19 Months Dr Jeyanthi a/p Suppiah 2020-05-27
In vitro COVID-19 Anti-Viral Screening of Herbal Formulations Coronavirus disease 19 infection herbal formulation therapy alone National Institutes of Health Malaysia Malaysia 2020-05-18 2020-12-31 54715, NMRR-20-874-54715 Phase Not Applicable Status not specified 1 7 Months Dr Mohd Ridzuan Bin Mohd Abd Razak 2020-05-27
Characteristics of Neonatal Covid-19 in Turkey Coronavirus disease 19 infection Healthy volunteers accepted, Newborn Infants (up to 5 months) Recep Tayyip Erdogan University Training and Research Hospital Turkish Neonatal Society Turkey 2020-05-01 2020-10-30 NCT04401540, NICU-COVID-TR Phase Not Applicable Recruiting 1 5 Months 90 Mehmet K Kanburoglu, M.D., Mehmet Kenan Kanburoglu, Mehmet Y Oncel, M.D. 2020-05-28
The Efficacy Comparing Daily and After-each-case Room Disinfection Coronavirus disease 19 infection after-each-case room disinfection alone, daily room disinfection alone The First Affiliated Hospital of Zhejiang Chinese Medical University China 2020-05-25 2020-06-10 DACD-HUY-2005, NCT04399005 Phase Not Applicable Recruiting 1 240 Bin Lu, Bin Lu, M.D., Bo Jin, Bachelor, Liang Huang, Liang Huang, Bachelor, Yue Hu, Yue Hu, M.D. 2020-05-28
SARS-CoV-2, Nasopharygeal swab, Saliva Coronavirus disease 19 infection RT-PCR alone Institute For Medical Research (Inc In Malaysia) Malaysia 2020-05-05 2020-06-30 54884, NMRR-20-860-54884 Phase Not Applicable Status not specified 1 1 Month Dr Mohan Rao Nageswara Rao 2020-05-27
Cardiopulmonary Inflammation and Multi-System Imaging During the Clinical Course of COVID-19 Infection in Asymptomatic and Symptomatic Persons Coronavirus disease 19 infection, Inflammatory disease, Pulmonary heart disease CT scans alone, MRI scans alone, biological sampling alone, bronchoscopy alone, ultrasound alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institutes of Health Clinical Center US 2020-05-21 2024-05-01 20-CC-0113, 200113, NCT04401449 Phase Not Applicable Recruiting 1 47 Months 92 Anthony F Suffredini, M.D. 2020-05-27
A phase II, randomized, placebo-controlled study to evaluate the safety and efficacy of KT-PC-301 for the treatment of acute respiratory distress syndrome symptoms in patients with moderate to severe COVID-19 infection Coronavirus disease 19 infection, Respiratory distress syndrome KT-PC-301 alone Koligo Therapeutics Inc US Phase 2 Clinical Planned 1 75 Mohamed Saad 2020-05-27
ICUCOVID-MY Coronavirus disease 19 infection University Malaya Medical Centre Malaysia 2020-05-31 2020-09-30 54772, NMRR-20-1037-54772 Phase Not Applicable Recruiting 1 4 Months ABDUL JABBAR BIN ISMAIL, Dr Nor Azim bin Mohd Yunos 2020-05-29
OVID: Enoxaparin for Primary Thromboprophylaxis in Ambulatory Patients With COVID-19 Blood clotting disorder, Coronavirus disease 19 infection enoxaparin sodium alone Low molecular weight heparin Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Zurich Centre Hospitalier Universitaire Vaudois, Clinica Luganese Moncucco, Hopitaux Universitaires De Geneve, Oncology Institute of Southern Switzerland, University Hospital Basel, University Hospital Inselspital, Berne Switzerland 2020-06-01 2021-04-14 NCT04400799, OVID, OVID TRIAL Phase 3 Clinical Not yet recruiting 1 10 Months 1000 Nils Kucher, Prof., Rebecca Spescha, Dr. sc. nat. 2020-05-27
A clinical trial of inactivated vaccine (COVID-19), KM Biologics for the potential treatment of COVID-19 infection Coronavirus disease 19 infection inactivated vaccine (COVID-19), KM Biologics alone KM Biologics Co Ltd Phase Not Applicable Planned 0 2020-05-29
Changing Of Egyptian Population Behavior Towards COVID-19 Outbreak Coronavirus disease 19 infection online survey alone Healthy volunteers accepted Damanhour University Egypt 2020-05-02 2021-04-01 COVID 19, NCT04401098 Phase Not Applicable Recruiting 1 11 Months 700 Amira Kassem, PHD, Amira kassem, PHD, Noha El Bassiouny, PHD, Noha El bassiouny, PHD 2020-05-27
HEP-COVID: Full Dose Heparin Versus Prophylactic Or Intermediate Dose Heparin in High Risk COVID-19 Patients Coronavirus disease 19 infection enoxaparin sodium alone Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Northwell Health Inc US 2020-04-26 2021-04-26 20-0340, HEP-COVID, NCT04401293 Phase 3 Clinical Recruiting 6 12 Months 308 Aaron Harrison, MD, Adrian Popp, MD, Alex C Spyropoulos, MD, Andrea Mignatti, MD, Barbara Shannon, RN, Christina Brennan, MD, Cynthia Price, NP, Damian Inlall, CCRC, Dana Kuziw, RN, Eugenia Gianos, MD, George Surguladze, MD, Gulru Sharifova, MD, Jane Hubert, RN, Janice Wang, MD, Jeremy Jacobson, MD, John Flynt, MD, Kevin Molina, Lisa Lumley, RN, Luis Gruberg, MD, Mangala Narasimhan, MD, Marc Cohen, MD, Mark Goldin, MD, Melissa Panzo, RN, Michael Krzyzak, MD, Nazish Ilyas, MD, Negin Hajizadeh, MD, Paul Maccaro, MD, Phyllis Suen, MD, Puneet Gandotra, MD, Richard Dima, MD, Sean Taylor, Wassim Diab, MD 2020-05-28
COVID-TRAUMA: Covid-19 and Reorganisation of Cancer Patient Care: Self-evaluation of Potential Post Traumatic Stress Disorder Coronavirus disease 19 infection, Post traumatic stress disorder Survey alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institut Paoli-Calmettes IPC France 2020-05-30 2020-11-30 COVID-TRAUMA, COVID-TRAUMA-IPC 2020-026, NCT04401046 Phase Not Applicable Not yet recruiting 1 6 Months 4000 Dominique Genre, MD, Gwenaelle GRAVIS, MD, Jihane PAKRADOUNI, PharmD, PhD 2020-05-29
Distance Learning for Dental Student During COVID-19 Pandemic Coronavirus disease 19 infection pediatric dentistry online course alone Cairo University Egypt 2020-05-01 2020-05-10 DISTANCE LEARNING ENVIRONMENT, NCT04401371 Phase Not Applicable Completed 1 418 Maha Moussa, Yasmin Mohamed Yousry 2020-05-27
Status of Management of Surgery in Beijing During COVID-19 Coronavirus disease 19 infection, Gastrointestinal disease surgery alone Beijing Friendship Hospital Beijing Chao-Yang Hospital, Beijing Hospital, China-Japan Friendship Hospital, Chinese PLA General Hospital, Peking Union Medical College Hospital, Peking University Cancer Hospital, Peking University First Hospital, Peking University Shougang Hospital, Peking University Third Hospital, People's Hospital Peking University, Xuanwu Hospital Of Capital Medical University China 2020-05-25 2020-06-07 BFH-SURGERYCOVID, NCT04401124 Phase Not Applicable Not yet recruiting 1 500 Kai Pang, M.D., Zhongtao Zhang, M.D. 2020-05-29
MONACOVID: How Routine Biomarkers and Blood Leucocytes Count Can Assist Diagnosis of COVID-19 in Emergency Department Coronavirus disease 19 infection, Viral pneumonia CT-scan alone, naso-pharyngeal swab sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Princesse Grace Monaco 2020-02-01 2020-05-15 20-06, MONACOVID, NCT04401241 Phase Not Applicable Completed 1 3 Months 257 2020-05-28
ACTT-II: Adaptive COVID-19 Treatment Trial 2 Coronavirus disease 19 infection baricitinib plus remdesivir COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, Jak1 tyrosine kinase inhibitor, Jak2 tyrosine kinase inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Allergy and Infectious Diseases US, Singapore, Japan 2020-05-08 2023-08-01 20-0006 ACTT-II, ACTT-II, NCT04401579 Phase 3 Clinical Recruiting 48 38 Months 1032 20-0006 Central Contact 2020-05-28
Randomized, Proof-of-Concept Trial to Evaluate the Safety and Explore the Effectiveness of Resveratrol for COVID-19 Coronavirus disease 19 infection Vitamin D3 plus resveratrol Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mount Carmel Health System US 2020-06-30 2020-11-30 MCCREARY2020, NCT04400890 Phase 2 Clinical Not yet recruiting 1 5 Months 200 Marvin R McCreary 2020-05-28
Acute impairment of renal function in COVID-19: study on incidence, risk factors and mortality Coronavirus disease 19 infection, Renal failure Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Unidade de Pesquisa Clínica - Hospital das Clínicas da Faculdade de Medicina de Botucatu Brazil 2020-05-01 30451520.6.0000.5411, CEP: 4.003.880, RBR-62y3h7, U1111-1251-0281 Phase Not Applicable Recruiting 1 1000 Welder Zamoner 2020-05-28
Everett Clinic study: A clinical study to evaluate the efficacy of ID NOW COVID-19 Rapid Test Coronavirus disease 19 infection ID NOW COVID-19 Rapid Test alone Abbott Laboratories Everett Clinic study Phase Not Applicable Status not specified 0 955 2020-05-29
Urgent care clinic study: A multisite clinical study to evaluate the efficacy of ID NOW COVID-19 Rapid Test Coronavirus disease 19 infection ID NOW COVID-19 Rapid Test alone Abbott Laboratories Urgent care clinic study Phase Not Applicable Status not specified 0 256 2020-05-29
Long-term Pulmonary Outcomes After Infection With Sars-CoV-2 Coronavirus disease 19 infection Lung imaging alone, Pulmonary function test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Aarhus University Denmark 2020-05-31 2022-12-31 33510, NCT04401163 Phase Not Applicable Not yet recruiting 1 31 Months 180 Elisabeth Bendstrup, MD, PhD, Søren S Haugen, MD 2020-05-28
PREVICHARM: Prevention of COVID-19 Infection in Nursing Homes by Chemoprophylaxis With Hydroxychloroquine Coronavirus disease 19 infection hydroxychloroquine (Dolquine) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundacion Publica Andaluza para la Investigacion de Malaga en Biomedicina y Salud, University of Malaga Instituto de Investigacion Biomedica de Malaga, Instituto de Salud Carlos III Spain 2020-05-15 2021-04-01 2020-002287-31, COV20/00565, NCT04400019, PREVICHARM, PREVICHARM Phase 2/Phase 3 Clinical Not yet recruiting 3 10 Months 1930 Gloria Luque, José M Morales-Asencio, PhD, José M Morales-Asencio, Professor, Juan C Morilla-Herrera, PhD, Ricardo Gómez-Huelgas, PhD 2020-05-29
TXA COVID-19 Clinical Trial Coronavirus disease 19 infection, Multiple organ failure, Renal injury TXA-127 alone Angiotensin II receptor modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Columbia University US 2020-06-30 2021-12-31 AAAT0535, NCT04401423 Phase 2 Clinical Not yet recruiting 1 18 Months 100 Jeanine D'Armiento, Jeanine D'Armiento, MD, PhD, Laura Fonseca 2020-05-29
Mavrilimumab to Reduce Progression of Acute Respiratory Failure in COVID-19 Pneumonia and Systemic Hyper-inflammation Coronavirus disease 19 infection, Hypoxia, Inflammatory disease, Respiratory failure, Viral pneumonia mavrilimumab alone C-reactive protein inhibitor, Chemokine CC22 ligand inhibitor, GM-CSF receptor antagonist, Hemoglobin scavenger receptor antagonist, Metalloprotease-1 inhibitor, Metalloprotease-3 inhibitor, Small inducible cytokine A17 ligand inhibitor, VEGF gene inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cleveland Clinic Foundation Kiniksa Pharmaceuticals Ltd US 2020-05-20 2021-05-31 IND 149324, IRB 20-523, NCT04399980 Phase 2 Clinical Recruiting 2 12 Months 60 Alice Goyanes, M. D., Calvin Sheng, M. D., Debases Sahoo, M.D., Narendrakumar Alappan, M. D., Ossama K Abou Hassan, M. D., Paul C Cremer, M. D., Prabalini Rajendram, M. D., Ravi Sunderkrishnan, M. D., Robier Aguillon-Prada, M. D., Shiddharth P Dugar, M. D., Tom Wang, M. D., Venu Menon, M. D., Yuki Kuramochi, BSN, RN 2020-05-28
Attitude and Perception Towards COVID-19 Pandemic Coronavirus disease 19 infection Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Zagazig University Egypt 2020-05-19 2020-08-31 NCT04400812, ZU#IRB#6138-17-5-2020 Phase Not Applicable Recruiting 1 3 Months 5000 Waheed Shouman 2020-05-29
Octagam 10% Therapy In COVID-19 Patients With Severe Disease Progression Coronavirus disease 19 infection Octagam 10% alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Octapharma AG, Octapharma USA US 2020-06-01 2020-09-30 2020-002482-34, GAM10-10, NCT04400058 Phase 3 Clinical Not yet recruiting 1 4 Months 54 Mikaela Raymond 2020-05-28
Mechanisms of Multi-organ Failure in COVID-19 Coronavirus disease 19 infection, Multiple organ failure Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Imperial College London UK 2020-05-18 2021-11-17 283783, NCT04399603 Phase Not Applicable Not yet recruiting 1 18 Months 120 2020-05-29
Niclosamide for Mild to Moderate COVID-19 Coronavirus disease 19 infection niclosamide alone, standard of care alone, telehealth monitoring alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tufts Medical Center US 2020-06-01 2020-11-30 NCT04399356, STUDY00000605 Phase 2 Clinical Not yet recruiting 1 6 Months 100 Dorothy Dulko, PhD, Harry P Selker, MD 2020-05-28
A retrospective, observational study to explore the clinical characteristics and prognosis of the new coronavirus 2019-nCoV patients combined with cardiovascular disease Cardiovascular disease, Coronavirus disease 19 infection angiotensin receptor blockers (ARBs) alone, angiotensin-converting enzyme inhibitors (ACEIs) alone Union Hospital Tongji Medical School Huazhong University Of Science & Technology China Phase Not Applicable Status not specified 1 112 2020-05-27
Flow Controlled Ventilation in ARDS Associated With COVID-19 Adult respiratory distress syndrome, Coronavirus disease 19 infection Evone-ventilator alone, flow controlled ventilation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hamad Medical Corp Qatar 2020-05-31 2020-08-31 MRC-05-018, NCT04399317 Phase Not Applicable Not yet recruiting 1 3 Months 20 Marcus Lance, MD, PhD, Nabil Shallik, MD 2020-05-29
Ivermectin-Azithromycin-Cholecalciferol (IvAzCol) Combination Therapy for COVID-19 (IvAzCol) Coronavirus disease 19 infection, Respiratory disease Variable regimens including azithromycin , cholecalciferol , ivermectin Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto De Seguridad Y Servicios Sociales De Los Trabajadores Del Estado Mexico 2020-03-15 2020-06-10 IVAZCOL, NCT04399746 Phase 2 Clinical Recruiting 1 2 Months 30 Guadalupe Espitia Hernandez, MD, PhD, Guadalupe Espitia, MD, PhD 2020-05-28
Effect of Lactobacillus on the Microbiome of Household Contacts Exposed to COVID-19 Coronavirus disease 19 infection Lactobaciltus rhamnosus GG alone Healthy volunteers accepted, Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Duke University US 2020-05-25 2022-05-25 NCT04399252, PRO00105674 Phase Not Applicable Not yet recruiting 1 24 Months 1000 Anthony Sung, MD, Lauren Bohannon 2020-05-28
Acceptance of Telemedicine During the COVID-19 Pandemic Coronavirus disease 19 infection telemedicine consultation alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Foundation for Health Research and Biomedical Valencia Philippines 2020-06-01 2020-10-31 NCT04400448, TELECOVID Phase Not Applicable Not yet recruiting 1 5 Months 200 Luis Sánchez Guillen 2020-05-29
Evaluation effect of Dinvl for Covid19 infection Coronavirus disease 19 infection, Viral pneumonia dinvl, Health Medicine Chemistry Company alone, usual treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Baqiyatallah Hospital Iran 2020-06-03 IR.BMSU.REC.1399.154, IRCT20200509047373N1 Phase 2/Phase 3 Clinical Not yet recruiting 1 60 Ahmad Hosseinpour, Mohsen Saberi 2020-05-29
Evaluation efficacy of 'curcumin and resveratrol' capsule in controlling symptoms in patients with COVID-19 Coronavirus disease 19 infection curcumin + resveratrol alone, routine treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bagheiat-allah University of Medical Sciences Iran 2020-05-16 IR.BMSU.REC.1399.129, IRCT20080901001165N56 Phase 3 Clinical Recruiting 1 60 Gholamhosein Alishiri, Morteza Izadi, Parisa Kianpour, Rouhollah Ahmadiyan, Yunes Panahi 2020-05-29
Cyclosporin for the Prevention and Treatment of COVID-19 Disease Coronavirus disease 19 infection, Respiratory failure cyclosporin alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shaheed Beheshti Medical University Iran 2020-03-20 IR.SBMU.NRITLD.REC.1399.058, IRCT20150107020592N22 Phase 3 Clinical Recruiting 1 60 Dr Seyyed Mohamadreza Hashemian, Seyed Mohammad Reza Hashemian 2020-05-28
Low dose whole lung irradiation for treatment of COVID-19 pneumonia Coronavirus disease 19 infection, Lung disease, Respiratory distress syndrome, Viral pneumonia low dose whole lung irradiation (100 Rads) alone Male, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tehran University of Medical Sciences Iran 2020-05-27 IR.TUMS.VCR.REC.1399.362, IRCT20170211032494N3 Phase 2 Clinical Recruiting 1 10 Dr. Mohammad Ali Sahraian, Nima Mousavi Darzikolaee 2020-05-28
Polio Vaccine and COVID-19 Coronavirus disease 19 infection oral polio vaccine (Razi Institute) alone Petroleum Industry Health Organization Iran 2020-06-13 IR.SUMS.REC.1399.183, IRCT20140428017469N1 Phase 3 Clinical Not yet recruiting 1 130000 Farrokh Habibzadeh, Habibollah Sami 2020-05-28
A Randomized Study to Assess the Effect of Genedrive 96 SARS-CoV-2 Kit in patients With COVID-19 Coronavirus disease 19 infection Genedrive 96 SARS-CoV-2 Kit alone Genedrive plc Phase Not Applicable Status not specified 0 180 2020-05-26
EMPOWER: BAME versus COVID Coronavirus disease 19 infection Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry, African Ancestry, Japanese Ancestry Future Genetics Limited UK 2020-07-01 2021-10-01 EMPOWER, EMPOWER-BAME VS COVID, NCT04399733 Phase Not Applicable Not yet recruiting 1 15 Months 12800 Dr Mohammed Kamran, Kash Arfan 2020-05-28
Hydroxychloroquine of pharmacokinetics in healthcare workers Coronavirus disease 19 infection Hydroxychloroquine sulphate alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Indian Council of Medical Research India 2020-05-25 83341, CTRI/2020/05/025242 Phase 1 Clinical Not yet recruiting 1 400 Dr Nithya Gogtay 2020-05-28
A study on salivary samples and nasopharyngeal samples in diagnosis of COVID-19 Disease Patients Coronavirus disease 19 infection salivary and nasopharyngeal sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Medanta The Medicity India 2020-05-19 CTRI/2020/05/025243 Phase Not Applicable Not yet recruiting 1 40 Dr Sushila Kataria, Dr Vikas Deswal, Kuldeep K Chauhan 2020-05-28
Ashwagandha for prevention against SARS-CoV-2 Infection: A Randomized, Hydroxychloroquine Controlled drug trial in high risk Health Care Providers Coronavirus disease 19 infection Ashwagandha (Withania somnifera) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Council of Scientific and Industrial Research (India), Ministry of Ayush India 2020-05-28 CTRI/2020/05/025332 Phase 2 Clinical Not yet recruiting 1 400 DR ARVIND CHOPRA 2020-05-27
hCT-MSCs for COVID-19 ARDS Coronavirus disease 19 infection, Respiratory distress syndrome human cord tissue mesenchymal stromal cells alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Duke University The Marcus Foundation Inc US 2020-06-01 2021-07-31 NCT04399889, PRO00105410 Phase 1/Phase 2 Clinical Not yet recruiting 1 14 Months 30 Bryan Frank, MD, Jennifer Baker, RN, Joanne Kurtzberg, MD, Julie Lopez, MD 2020-05-29
To Study Clinical Characteristics, Treatment Outcome of Coronavirus (COVID-19) Patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) CIMS Hospital Pvt. Ltd. India 2020-05-26 COVID-19/20-01, CTRI/2020/05/025247 Phase Not Applicable Not yet recruiting 1 500 Dr Amit Patel, Dr Hardik Shah, Dr Surabhi Madan 2020-05-28
To Study effectiveness and outcomes of Unani Medicine prophylactic interventions on population at risk of COVID-19 Coronavirus disease 19 infection Variable regimens including Khameera Marwareed , Tiryaq-e-Arba , Unani Joshanda Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Central Council for Research in Unani Medicine India 2020-05-29 CCRUM 05/2020/01, CTRI/2020/05/025254 Phase 3 Clinical Not yet recruiting 7 40000 Dr Ahmad Minhajuddin, Dr Arsheed Iqbal, Dr H A Lari, Dr Maqbool Ahmed, Dr Naheed Parveen, Dr Parvez Khan, Dr Pradeep Kumar, Dr Shagufta Parveen, Prof Abdul Wadood, Prof Asim Ali Khan 2020-05-29
An observational study on QT interval changes with Hydroxychloroquine used as prophylaxis in COVID exposure risk individuals Coronavirus disease 19 infection hydroxychloroquine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Vydehi Institute of Nursing Sciences & Research CentreVydehi Institute of Nursing Sciences & Research Centre India 2020-06-15 CTRI/2020/05/025289 Phase Not Applicable Not yet recruiting 1 50 P Vamsavardhana Reddy 2020-05-28
The Utility of Bedside Lung Ultrasonography on Diagnosis of COVID-19 Coronavirus disease 19 infection, Viral pneumonia lung ultrasound alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Istanbul Bakirkoy Maternity and Children Diseases Hospital Turkey 2020-05-10 2020-09-10 KSSEAH--, NCT04399681 Phase Not Applicable Recruiting 1 4 Months 100 Ramazan Guven, Seda Yilmaz Semerci 2020-05-26
Impact of effect of Ayurvedic treatment on novel Corona virus disease Coronavirus disease 19 infection Variable regimens including Anu Taila , Ashwagandha , Giloy Extract , Swasari Ras , Tulsi Extract Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) NIMS University, Patanjali Research Foundation India 2020-05-29 CTRI/2020/05/025273 Phase 2 Clinical Recruiting 1 120 Dr Abhishek Sharma, Dr Ganpat Devpura 2020-05-28
HPCOV-19: A study to assess the efficacy of Homoeopathic medicine in the prevention of Covid-19 Coronavirus disease 19 infection Arsenicum album 30 alone Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) District Homeopathic Medical Office India 2020-05-30 CTRI/2020/05/025272, HPCOV-19 Phase 3 Clinical Not yet recruiting 1 800 Dr Boban J, Dr Pramod P, Dr S Balamani 2020-05-28
Corona virus in tears Coronavirus disease 19 infection, SARS coronavirus infection Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Maulana Azad Medical College India 2020-05-24 CTRI/2020/05/025291 Phase Not Applicable Not yet recruiting 1 70 Dr RITU ARORA 2020-05-26
Ozone Therapy in the Prevention of COVID-19 Infection Coronavirus disease 19 infection Turkozone Blue-S medical ozone generator alone, ozone therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Marmara University Turkey 2020-05-06 2020-05-17 2761, NCT04400006 Phase Not Applicable Completed 1 71 Kardelen Gencer 2020-05-26
CIRCA-19: Cellular Immuno-Therapy for COVID-19 Acute Respiratory Distress Syndrome - Vanguard Coronavirus disease 19 infection, Respiratory distress syndrome mesenchymal stromal cells alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ottawa Hospital Research Institute Stem Cell Network Canada 2020-05-31 2021-06-30 20200243-01H, CIRCA-19, NCT04400032 Phase 1 Clinical Not yet recruiting 1 13 Months 9 Bernard Thebaud, MD, David Courtman, PhD, Dean Fergusson, PhD, Duncan J Stewart, MD, Manoj Lalu, MD, Shane English, MD 2020-05-26
Siddha Intervention Population Study Coronavirus disease 19 infection Kabasurakudineer Nilavembukudineer alone Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Central Council for Research in Siddha Ministry of Ayush India 2020-05-25 CTRI/2020/05/025298 Phase Not Applicable Not yet recruiting 1 21500 DrKKanakavalli, PSathiyarajeswaran 2020-05-26
Study to assess efficacy of Ivermectin as prophylaxis of COVID -19 Coronavirus disease 19 infection ivermectin alone Chloride channel modulator Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) RD Gardi Medical College India 2020-05-27 CTRI/2020/05/025333 Phase 2 Clinical Not yet recruiting 1 2000 Dr Ashish Pathak, Dr Sunil Rathi 2020-05-26
The effects of Ginger on clinical manifestations and paraclinical features of patients with COVID-19: A randomized, double-blind, placebo-control clinical trial Coronavirus disease 19 infection Vomigone (Dineh Iran Pharmaceutical Company) alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bandare-abbas University of Medical Sciences Iran 2020-05-21 IR.HUMS.REC.1399.130, IRCT20200506047323N1 Phase 3 Clinical Recruiting 1 84 Mohammad Fathalipour, Parivash Davoodian, Teamur Aghamolaei 2020-05-26
Ayurveda as Prophylaxis for Suspected COVID-19 Patients Coronavirus disease 19 infection Ayurveda traetment alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) British Ayurvedic Medical Council All Party Parliamentary Group - Indian Traditional Sciences, Warwick University UK 2020-06-10 2020-10-01 BAMC01, NCT04395976 Phase Not Applicable Not yet recruiting 1 3 Months 120 Amarjeet S Bhamra, Avtar Singh, Jaydeep Joshi, Mahesh Mathpati, Mauroof Anthique, Neha Sharma, Shantha Godagama, Venkata Joshi, Vishwes Kulkarni 2020-05-26
Investigating the efficacy and safety of N-Acetyl Cysteine (NAC) inhalation spray in controlling the symptoms of patients with COVID-19 Coronavirus disease 19 infection N-acetyl-cysteine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bagheiat-allah University of Medical Sciences Iran 2020-05-13 IR.BMSU.REC.1399.123, IRCT20080901001165N55 Phase 3 Clinical Recruiting 1 72 Dr. Rezaeiyan, Mostafa Ghanei, Parisa Kianpour, Yunes Panahi 2020-05-26
Vitamin D and COVID-19: Evaluation of the likely beneficial effects of vitamin D on infection with coronavirus Coronavirus disease 19 infection cholecalciferol alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundación Para La Investigación E Innovación Biosanitaria En El Principado De Asturias (Finba) Spain 2020-05-19 2020-002274-28, COVID-VIT-D, Vitamin D and COVID-19 Phase 4 Clinical Recruiting 1 60 Managing director 2020-05-27
Convalescent Plasma in the treatment of 6 COVID-19 Patients Coronavirus disease 19 infection convalescent plasma alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Affiliated Hospital of Zunyi Medical College, Guizhou Provincial Jiangjunshan Hospital China 2020-01-29 2020-04-30 ChiCTR2000033056 Phase 0 Clinical No longer recruiting 1 3 Months 6 Zhang Wei 2020-05-27
The research of novel coronavirus pneumonia (COVID-19) patients' immune status and severity of disease Coronavirus disease 19 infection, Viral pneumonia Human immunoglobulin alone, Xuebijing alone, Human immunoglobulin plus Xuebijing Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) First Hospital of Changsha China 2020-03-01 2021-03-01 ChiCTR2000033190 Phase 0 Clinical No longer recruiting 1 12 Months 60 Ailian Lv, Yuanlin Xie 2020-05-27
Novel coronavirus pneumonia (COVID-19) and Symptomatic Venous Thromboembolism: a Multicenter Retrospective Study Coronavirus disease 19 infection, Viral pneumonia Union Hospital Tongji Medical School Huazhong University Of Science & Technology National Natural Science Foundation of China China 2020-05-20 2020-05-30 ChiCTR2000033055 Phase Not Applicable Not yet recruiting 15 300 Liang Tang, Yu Hu 2020-05-27
A randomized, open-label, blank-controlled, multicenter trial for Shuang-Huang-Lian oral solution in the treatment of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Lianhua Qingwen alone, shuanghuanglian oral solution alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The First Affiliated Hospital of Wenzhou Medical University HPGC Renmintongtai Pharmaceutical Corporation China 2020-02-12 2020-04-20 ChiCTR2000033133, ChiMCTR2000003320 Phase Not Applicable No longer recruiting 1 2 Months 60 Chen Yongping, Liu Cailing 2020-05-27
A follow-up study about clinically diagnosed cases of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The First Affiliated Hospital of Zhengzhou University Science and Technology Department of Henan Province China 2020-02-01 2022-02-01 ChiCTR2000033186 Phase Not Applicable Recruiting 2 24 Months 118 An Xiaocai, Xu Aiguo 2020-05-27
Associations between suboptimal health status and TraditChinese Medicine constitution of medical staff fighting the disease, recovered COVID-19 patients and the general public under the outbreak of novel coronavirus pneumonia: an epidemiological study Coronavirus disease 19 infection, Viral pneumonia Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Southern Medical University China 2020-05-20 2021-12-31 ChiCTR2000033108, ChiMCTR2000003319 Phase Not Applicable Recruiting 1 19 Months 600 Chen Jieyu, Zhao Xiaoshan 2020-05-27
Online parent training for reducing parenting stress during the coronavirus pandemic Acute stress disorder, Coronavirus disease 19 infection online forum sharing alone, online parent-training program alone, personal feedback alone Healthy volunteers accepted Heim Pal Children's Hospital Eotvos Lorand University Hungary 2020-04-06 2020-12-15 2020/185, ISRCTN15254871 Phase Not Applicable Recruiting 2 8 Months 300 Dr Monika Miklosi 2020-05-29
Clinical characteristics and outcomes of novel coronavirus pneumonia (COVID-19) patients with pre-existing HBV infection Coronavirus disease 19 infection, Hepatitis B virus infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institute of Field Surgery Third Military Medical University of the Chinese PLA China 2020-05-01 2020-08-01 ChiCTR2000033107 Phase Not Applicable No longer recruiting 1 3 Months 72 Chen Dongfeng, Wang Wensheng, Wen Liangzhi 2020-05-27
CYCOV-II: Cytokine adsorption in patients with severe COVID-19 pneumonia requiring extracorporeal membrane oxygenation – randomized, controlled, open-label intervention, multicenter trial Coronavirus disease 19 infection, Viral pneumonia CytoSorb cytokine adsorber alone, venovenous extracorporeal membrane oxygenation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Klinikum der Albert-Ludwigs Universitaet Freiburg Germany 2020-05-31 285/20, CYCOV-II, DRKS00021248, DRKS21300 Phase Not Applicable Not yet recruiting 7 80 Alexander Supady 2020-05-27
COWUPAK: A prospective trial on the prevalence and the variation over time of SARS-CoV-2 antibodies in hospital health care workers (COVID-19) Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hygiene Helios Klinik Wuppertal Germany 2020-05-12 94/2020, COWUPAK, DRKS00021729 Phase Not Applicable Recruiting 1 300 Felix Giebel, Parviz Ahmad-Nejad 2020-05-27
Evaluation of the effect of thyme on corona patients Coronavirus disease 19 infection hospital protocol based medication treatment alone, thyme syrup (Gol Daru Company) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Zanjan University of Medical Sciences Iran 2020-05-30 047‏IR.ZUMS.REC.1399, IRCT20200506047319N1 Phase Not Applicable Not yet recruiting 1 100 Alireza Shoghli, Narjes Khavasi 2020-05-28
COVAYDE: COVid-19: Awake Proning and High-flow Nasal Cannula in respiratorY DistrEss Coronavirus disease 19 infection, Respiratory distress syndrome Awake Prone Positioning alone, nasal high-flow oxygen alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopital de Verdun Canada 2020-05-15 2020-12-31 2021-01, COVAYDE, NCT04395144 Phase Not Applicable Recruiting 1 7 Months 346 Ivan Pavlov, MD 2020-05-28
COELIOCOVID: Risk of Air Contamination During Visceral Surgery in COVID19 Patients Coronavirus disease 19 infection, Respiratory tract infection Air sampling alone, biological fluid sampling alone, operating room surfaces sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Regional Universitaire de Lille France 2020-05-31 2020-10-31 2020-A01461-38, 2020_44, COELIOCOVID, NCT04395599 Phase Not Applicable Not yet recruiting 1 5 Months 40 Robert CAIAZZO, MD,PhD 2020-05-28
Follow up study of convalescent patients of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Union Hospital Tongji Medical School Huazhong University Of Science & Technology National Natural Science Foundation of China China 2020-02-20 2021-02-20 ChiCTR2000033105 Phase Not Applicable Recruiting 1 12 Months 400 Huang Qi, Jin Yang 2020-05-28
Corona virus disease 2019 (COVID-19) antibody seroprevalence of the medical staff in the hospital with cluster of COVID-19 Coronavirus disease 19 infection Elecsys Anti-SARS-CoV-2 immunoassay alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) NTT West Osaka Hospital, Osaka City University Graduate School of Medicine, Osaka Police Hospital Japan 2020-05-25 UMIN000040453 Phase Not Applicable Not yet recruiting 2 2500 Atsushi Ogata 2020-05-29
A trial to assess nafamostat for COVID-19 infection Coronavirus disease 19 infection nafamostat (COVID-19 infection), Institut Pasteur Korea alone Serine protease inhibitor, Transmembrane serine protease 2 inhibitor Institut Pasteur Korea South Korea Phase Not Applicable Not yet recruiting 1 Bae In-gyu 2020-05-26
Clinical study for rapid detection of novel coronavirus pneumonia (COVID-19) nucleic acid Coronavirus disease 19 infection, Viral pneumonia test reagent alone Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hubei Zhongshan Hospital Affiliated to Wuhan University Anbio (Xiamen) Products Inc. China 2020-03-07 2020-03-20 ChiCTR2000033104 Phase Not Applicable No longer recruiting 1 Daming Wang, Yang Lei 2020-05-27
Usefulness of PCR testing for SARS-CoV-2 before gastrointestinal endoscopy and hospitalization Coronavirus disease 19 infection PCR testing alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chiba University Japan 2023-03-31 UMIN000040516 Phase Not Applicable Recruiting 1 200 Naoya Kato, Yuki Ohta 2020-05-27
A randomized controlled trial for determination of the clinical effect of Internet-assisted pulmonary rehabilitation on patients with novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Internet-assisted pulmonary rehabilitation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The First Hospital Of China Medical University China Medical University (China) China 2020-02-25 2020-09-01 ChiCTR2000033057 Phase Not Applicable Recruiting 3 6 Months 160 Gang Hou 2020-05-27
A 14-day, long prospective, multi-site, two-armed, randomized, open-label study is to investigate the effects of Vascepa on inflammatory biomarkers in individuals with COVID-19 Coronavirus disease 19 infection icosapent ethyl, Amarin alone Apolipoprotein B antagonist, Phospholipase A2 inhibitor Canadian Medical and Surgical Knowledge Translation Research Group, HLS Therapeutics Inc Amarin Corp plc Canada 2020-05-31 Phase Not Applicable Planned 1 100 Dr. Deepak L. Bhatt, Dr. Subodh Verma 2020-05-26
Investigating blood clotting changes in patients with COVID-19 Coronavirus disease 19 infection, Thrombosis Oxford University Hospitals NHS Trust UK 2020-03-01 2020-11-30 14937, IRAS 282457, ISRCTN64783542 Phase Not Applicable Recruiting 1 9 Months Dr Curry 2020-05-27
PICO: A pilot study of the ability of povidone-iodine (PVP-I) 0.5% aqueous solution oral/nasal spray and mouthwash to kill the SARS-CoV-2 virus in people with COVID-19 Coronavirus disease 19 infection mouthwash alone, povidone-iodine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Royal Surrey County Hospital NHS Trust British Association of Oral and Maxillofacial Surgeons, Royal Surrey County Hospital Charity, Surrey Peri-Operative Anaesthesia and Critical Care Collaborative Research Group (SPACER) UK 2020-03-15 2020-07-30 IRAS 283182, ISRCTN13447477, PICO Phase 2 Clinical Recruiting 1 4 Months 25 Dr Justin Kirk-Bayley 2020-05-26
Psycho-behavioral response to the 2019-nCoV Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry The University of Hong Kong Hong Kong 2020-02-04 20200131whpp, HKUCTR-2855, UW 20-120 Phase Not Applicable Not yet recruiting 1 1000 Dr. Qiuyan Liao, HKUCTR Administrator 2020-05-27
BREATH-19: Clinical trial to evaluate the efficacy and safety of tocilizumab for treating patients with COVID-19 pneumonia Coronavirus disease 19 infection, Viral pneumonia tocilizumab (intravenous), Roche/Chugai alone IL-6 receptor antagonist, IL-6 receptor modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundacion SEIMC-GESIDA ROCHE Espana Spain 2020-05-15 2020-001995-13, BREATH-19, BREATH-19, FSG011-20 Phase 2 Clinical Recruiting 1 500 Dynamic Science S.L., Raúl Montalbán Casado 2020-05-26
A study to determine if a new COVID-19 vaccine safely generates protective immune responses in adults in Kenya Coronavirus disease 19 infection AZD-1222 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) University of Oxford Wellcome Trust For Human Genetics Kenya 2020-05-31 2022-05-31 PACTR202005681895696 Phase 1/Phase 2 Clinical Not yet recruiting 1 24 Months 400 George Warimwe, Marianne Munene, Philip Bejon 2020-05-25
Folic acid: A new suggested prevention and treatment of COVID-19 infection Coronavirus disease 19 infection folic acid alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cairo University Egypt 2020-04-20 2020-05-21 PACTR202005599385499 Phase Not Applicable Not yet recruiting 1 1 Month 60 Ahmed Farag, Hala Salah, Nadia Ouda 2020-05-25
SARS-CoV-2 in Personal Protective Equipment Coronavirus disease 19 infection Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Jose de San Martin Hospital de Clinicas Argentina 2020-05-15 2020-07-30 NCT04398043, RT PCR EN EPP Phase Not Applicable Not yet recruiting 1 2 Months 16 Bernardo Bergroth, Bernardo bergroth, MD, Claudio Yaryour, MD 2020-05-25
An Investigation of the Efficacy and Safety of Favipiravir in COVID-19 Patients without Pneumonia − An open-label, randomized, controlled study Coronavirus disease 19 infection favipiravir alone, supportive care alone RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Faculty of Medicine Siriraj Hospital, Mahidol University, Health System Research Institute (HSRI) Thailand 2020-06-01 TCTR20200514001 Phase 2/Phase 3 Clinical Not yet recruiting 1 96 Rujipas Sirijatuphat 2020-05-25
Euro-COVIMID: Prevalence and Seroconversion of COVID-19 in Autoimmune Diseases in Europe Autoimmune disease, Coronavirus disease 19 infection, Rheumatoid arthritis, Sjoegrens syndrome, Spondylarthritis, Systemic lupus erythematosus, Temporal arteritis serological test alone, usual care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopital Universitaire de la Pitie Salpetriere Rheumazentrum Ruhrgebiet, Universidad Complutense de Madrid, University College London, University of Coimbra, University of Ferrara France 2020-05-31 2020-12-31 2020-A01371-38, Euro-COVIMID, NCT04397237 Phase Not Applicable Not yet recruiting 1 7 Months 3600 David Saadoun, MD, PhD, Laure Gossec, MD, PhD 2020-05-25
SMELLY: Prevalence of the loss of smell in patients with COVID-19 Coronavirus disease 19 infection, Olfactory nerve disorder University of Pennsylvania Smell Identification Test (UPSIT) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Royal North Shore Hospital Australia 2020-05-03 2020-08-31 ACTRN12620000575932, SMELLY Phase Not Applicable Recruiting 1 3 Months 100 A/Prof Roderick Clifton-Bligh, Ms Liza Nery 2020-05-26
Open, randomized, multicenter, comparative study of the efficacy and safety of the drug AREPLIVIR, film-coated tablets (OOO PROMOMED RUS, Russia) in patients hospitalized with COVID-19 Coronavirus disease 19 infection favipiravie (Areplivir), Promomed Rus alone Promomed Rus Russian Federation 2020-05-21 2020-12-31 FAV052020 Phase 3 Clinical Status not specified 5 7 Months 210 2020-05-25
Multicenter, open-label, randomized trial of the efficacy and safety of TL-FVP-t compared to standard therapy in parallel groups in patients with mild to moderate coronavirus infection (SARS-CoV-2/COVID-19) Coronavirus disease 19 infection favipiravir (TL-FVP-t), Technology of Medicines alone Technology of Medicines LLC Russian Federation 2020-05-20 2022-12-31 TL-FVP-t-01 Phase 3 Clinical Status not specified 7 31 Months 200 2020-05-25
BEAT COVID-19: Randomised clinical trial of interventions for the treatment of COVID-19 in the community setting for high risk older people Coronavirus disease 19 infection hydroxychloroquine alone Middle-aged Adults (45-64 yrs) University of Sydney National Health and Medical Research Council Australia 2013-08-03 ACTRN12620000566932, BEAT COVID-19 Phase 3 Clinical Not yet recruiting 1 3000 Ms Kate Wilson, Prof Guy Marks 2020-05-25
An international, multicenter, adaptive, randomized, open, controlled trial to evaluate the efficacy and safety of radotinib in the treatment of hospitalized patients with SARS-CoV-2 coronavirus infection (COVID-19) Coronavirus disease 19 infection radotinib alone Abl tyrosine kinase inhibitor, Bcr protein inhibitor, Tyrosine protein kinase ABL1 inhibitor Il-Yang Pharmaceutical Co Russian Federation 2020-05-14 2021-04-30 CL01072079 Phase 3 Clinical Status not specified 8 11 Months 180 2020-05-22
ACT-20 in Patients With Severe COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia ACT-20 alone, Conventional treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Aspire Health Science LLC 2020-05-31 2020-10-31 AHS 20-03, NCT04398303 Phase 1/Phase 2 Clinical Not yet recruiting 0 5 Months 70 Laura Fairbairn 2020-05-25
ECMO-SARS: Extracorporeal Membrane Oxygenation (ECMO) and Coronavirus Disease (COVID) 19 Cardiac failure, Coronavirus disease 19 infection, Respiratory distress syndrome extracorporeal membrane oxygenation therapy alone Rennes University Hospital France 2020-04-21 2020-10-21 35RC20_8979 ECMO-SARS, ECMO-SARS, NCT04397588 Phase Not Applicable Recruiting 41 6 Months 300 Alexandre OUATTARA, Professor, Alizée Porto, Doctor, André Vincentelli, Professor, André Vincentelli, professor, Antoine Guillon, Doctore, Bernard Cholley, Professor, Bertrand Rozec, Doctor, Bruno Levy, Professor, Claire Roger, Doctor, Claudio Barbanti, Doctor, Corentin Lacroix, Doctor, Cyril Cadoz, Doctor, Cécile Ferragu, DRI, Emmanuel Besnier, Doctor, François Labaste, Doctor, Guillaume Flicoteaux, Doctor, Gwenhaël COLIN, Doctor, Jean-Luc. Fellahi, Professor, Jerome Jouan, Doctor, Jordi Matiello, Doctor, Kais Brini, Doctor, Lucie Gaide-chevronnay, Doctor, Marc-Olivier FISCHER, Professor, Matthias CASTANIER, doctor, Nicolas Allou, Doctor, Nicolas BISCHOFF, Doctor, Nicolas D'OSTREVY, Doctor, Nicolas Mongardon, Doctor, Nicolas Nesseler, Doctor, Nicolas Nesseler, doctor, Olaf Mercier, professor, Olivier DESEBBE, Doctor, Olivier Fabre, Doctor, Olivier Fouquet, Doctor, Olivier Huet, professor, Philippe Gaudard, Doctor, Pierre Fillatre, Doctor, Pierre Guinot, Doctor, Pierre-Emmanuel Falcoz, Professor, Roxane NICOLAS, Sophie Provenchère, Doctor, Stéphane Aubert, Doctor, Vito Giovanni Ruggieri, Professor, Yannick Fedun, Doctor 2020-05-25
OHSCAR: Survival of patients suffering an out-of-hospital cardiac arrest treated by emergency services in Spain during the COVID-19 pandemic and One year later Cardiac arrest, Coronavirus disease 19 infection Andalusian School of Public Health, Sistema d'Emergències Mèdiques (SEM) Spain 2020-01-23 2021-12-31 ISRCTN10437835, OHSCAR, OHSCAR 3 Phase Not Applicable Recruiting 14 23 Months Dr RosellOrtiz 2020-05-29
Myocardial Injury and Major Adverse Outcomes in Patients With COVID-19 Coronavirus disease 19 infection, Heart injury Mount Sinai Medical Center US 2020-05-31 2022-03-31 GCO 20-0965, NCT04397939 Phase Not Applicable Not yet recruiting 2 22 Months 5000 Annapoorna Kini, MD, Yuliya Vengrenyuk, PhD 2020-05-26
CO-QUETTES: COVID-19: Study of Inflammasome and Platelets Functions Coronavirus disease 19 infection, Viral pneumonia blood sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire de Toulouse France 2020-04-16 2021-04-30 CO-QUETTES, NCT04397822, RC31/20/0142 Phase Not Applicable Recruiting 1 12 Months 60 Fanny BOUNES 2020-05-25
NO-COVER: iNOPulse for COVID-19 Coronavirus disease 19 infection, Hypoxia, Viral pneumonia nitric oxide (inhaled, INOpulse), Bellerophon plus oxygen Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Miami Bellerophon Therapeutics LLC US 2020-07-01 2021-01-15 20200449, NCT04398290, NO-COVER Phase 2 Clinical Not yet recruiting 1 6 Months 30 Roger A Alvarez, D.O. 2020-05-25
Intensive Care Associated Complications and Outcome of Acute Respiratory Distress Syndrome Due to COVID-19 Adult respiratory distress syndrome, Coronavirus disease 19 infection, Myopathy Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Inselspital, Berne Switzerland 2020-04-09 2021-12-31 2020-00730, NCT04397172 Phase Not Applicable Recruiting 1 20 Months 50 Nicole Söll, Nicoles Söll, Werner Z`Graggen, MD 2020-05-26
Nebulized Heparin for the Treatment of COVID-19 Induced Lung Injury Adult respiratory distress syndrome, Coronavirus disease 19 infection, Lung injury nebulized heparin alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Frederick Memorial Hospital US 2020-06-01 2020-12-31 FHHEP518, NCT04397510 Phase 4 Clinical Not yet recruiting 1 7 Months 50 Thomas Smoot, Thomas Smoot, PharmD 2020-05-25
PSYCOV-CV: Psychological Impact of COVID-19 Quarantine and Worsening of Cardiovascular Risk in the French General Population Acute stress disorder, Anxiety disorder, Cardiovascular disease, Coronavirus disease 19 infection, Depression Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire de Toulouse France 2020-04-17 2021-04-20 NCT04397835, PSYCOV-CV, RC31/20/0135 Phase Not Applicable Recruiting 1 12 Months 800 Emilie Bérard, Emilie Bérard, MD PhD, Emilie Bérard, MD, PHD 2020-05-25
Mobile Health Study and Enhanced Symptom Monitoring in COVID-19 Cancer Patients Cancer, Coronavirus disease 19 infection chemotherapy alone, mHealth app alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Oklahoma US 2020-06-30 2021-12-31 COVID-19 MOBILE HEALTH, NCT04397614 Phase Not Applicable Not yet recruiting 1 18 Months 500 Katherine Moxley, MD, Lead Oncology Nurse, Michael Businelle, PhD 2020-05-25
COG-UK HOCI: How effective are infection prevention and control measures that are informed by genetic analysis of coronavirus (rapid and standard) at preventing COVID-19 in NHS hospitals? Coronavirus disease 19 infection University College London COG-UK Consortium (UK) UK 2020-03-17 2021-04-30 COG-UK HOCI, CTU/2020/353, IRAS 283014, ISRCTN50212645 Phase 3 Clinical Not yet recruiting 4 13 Months 2000 James Blackstone, Prof Judith Breuer 2020-05-26
RT-PCR on Conjunctival Sample for the Detection of SARS-CoV-2 in Patients With Covid-19 Conjunctivitis, Coronavirus disease 19 infection Conjunctival RT PCR alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Versailles University Hospital France 2020-05-15 2020-11-15 NCT04397666, P20/09, P20/09_COVEYES Phase Not Applicable Recruiting 1 6 Months 68 Edouard KOCH, Edouard KOCH, coordonator investigator 2020-05-25
COVID3T: COVID-19 Thales Thermography Triage : Thermal Camera Feasibility Study Coronavirus disease 19 infection thermal camera alone, thermography alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) NHS Greater Glasgow and Clyde UK 2020-05-20 2020-07-01 COVID3T, INGC20AE209, NCT04397380 Phase Not Applicable Not yet recruiting 1 1 Month 100 Barry Connor, PhD, Dan Forbes, MBChB, David J Lowe, MBChB, David Lowe, MBChB, Iain D Carrie, PhD, Malcolm WG Gordon, MBChb 2020-05-26
COMBAT-19: Mavrilimumab in Severe COVID-19 Pneumonia and Hyper-inflammation (COMBAT-19) Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia mavrilimumab alone, standard of care alone C-reactive protein inhibitor, Chemokine CC22 ligand inhibitor, GM-CSF receptor antagonist, Hemoglobin scavenger receptor antagonist, Metalloprotease-1 inhibitor, Metalloprotease-3 inhibitor, Small inducible cytokine A17 ligand inhibitor, VEGF gene inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ospedale San Raffaele Italy 2020-05-22 2020-11-22 COMBAT-19, COMBAT-19, NCT04397497 Phase 2 Clinical Not yet recruiting 3 6 Months 50 Giacomo De Luca, MD, Lorenzo Dagna, MD 2020-05-27
CACOVID-19: The GCO-002 CACOVID-19 Cohort: a French, Nationwide, Multicenter Study of COVID-19 Infected Cancer Patients Anal tumor, Appendix adenoma, Biliary cancer, Bladder cancer, Brain tumor, Breast tumor, Central nervous system tumor, Colorectal tumor, Coronavirus disease 19 infection, Endometrioid carcinoma, Esophagus tumor, Gastrointestinal stromal tumor, Gastrointestinal tumor, Genitourinary tract tumor, Head and neck tumor, Larynx tumor, Liver tumor, Mesothelioma, Mouth tumor, Nasal cancer, Nasopharyngeal carcinoma, Neuroendocrine tumor, Non-small-cell lung cancer, Ovary tumor, Pancreas tumor, Peritoneal tumor, Pharynx tumor, Prostate tumor, Renal tumor, Salivary gland cancer, Skin cancer, Small intestine cancer, Small-cell lung cancer, Stomach tumor, Urinary tract tumor, Uterine cervix tumor, Vulvar intraepithelial neoplasia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Federation Francophone de Cancerologie Digestive ARCAGY/ GINECO GROUP, Association des Neuro-OnCologues d'Expression Francaise, Groupe Cooperateur Multidisciplinaire en Oncologie, Groupe Oncologie Radiotherapie Tete et Cou, IFCT France 2020-04-03 2020-09-01 CACOVID-19, GCO002 CACOVID-19, NCT04397575 Phase Not Applicable Recruiting 5 4 Months 1000 Anne-Laure PELLETIER, Arnaud BOUTAN-LAROZE, Astrid LIEVRE, PhD, Carole VITELLIUS, Cécile GIRAULT, Gaël GOUJON, Jean-Baptiste BACHET, Julie PHILIP, O. Bouche, MD, Olivier LELEU, Touraj MANSOURBAKHT 2020-05-27
Study of the Safety of Therapeutic Treatment With Immunomodulatory MSC in Adults With COVID-19 Infection Requiring Mechanical Ventilation Coronavirus disease 19 infection, Respiratory distress syndrome BM-Allo-MSC alone, current supporting care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) NantKwest Inc Be The Match BioTherapies US 2020-06-30 2021-06-30 NCT04397796, QUILT-COVID-19-MSC Phase 1b Clinical Not yet recruiting 1 12 Months 45 Lennie Sender, MD 2020-05-27
Blood Collection Study From COVID-19 Convalescents to Identify Immunogenic Viral Epitopes Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) TScan Therapeutics Inc US 2020-04-09 2020-07-31 1586788, NCT04397900 Phase Not Applicable Recruiting 2 3 Months 80 Abby Richardson, Joana Achanfuo-Yeboah, CRA, Kenneth J Olivier, PhD 2020-05-25
Efficacy of Early Prone Positioning in Non-Mechanical Ventilation novel coronavirus pneumonia (COVID-19) Patients with Severe Hypoxia- a single-center prospective cohort study Coronavirus disease 19 infection, Hypoxia, Viral pneumonia prone position alone Tongji Medical College China 2020-02-01 2020-03-31 ChiCTR2000033053 Phase 0 Clinical Completed 1 2 Months 60 Zang Xuefeng 2020-05-25
Effect of high dose intravenous vitamin C on moderate novel coronavirus pneumonia (COVID-19) patients: a medical records based retrospective study Coronavirus disease 19 infection, Viral pneumonia vitamin C alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rui Jin Hospital China 2020-01-01 2020-06-30 ChiCTR2000033050 Phase Not Applicable Recruiting 1 6 Months 110 Bing Zhao, Enqiang Mao 2020-05-25
Effect of Laris - Hyssop combined herbal distilled on the improving clinical and paraclinical symptoms in patients with COVID-19 Coronavirus disease 19 infection Laris-Hyssop distillate alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Tabriz Iran 2020-05-25 2020-07-20 IR.TBZMED.REC.1399.027, IRCT20200518047497N1 Phase Not Applicable Recruiting 2 1 Month 80 Azizeh Farshbaf-Khalili, Javad Ahmadian heris 2020-05-29
A clinical study for the efficacy and safety of artemisinin-pipequine tablets in the treatment of the mild or common type novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia artemisinin-piperaquine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hongqi hospital of Mudanjing medical university Guangzhou University of Traditional Chinese Medicine China 2020-05-19 2020-12-31 ChiCTR2000033049 Phase 4 Clinical Not yet recruiting 1 7 Months Fengjie Xie, Hongying Zhang 2020-05-25
RECAP: Remote Monitoring of Cancer Patients With Suspected Covid-19 Coronavirus disease 19 infection, Hematological neoplasm, Sepsis, Solid tumor biosensor monitoring alone, continuous physiological ambulatory monitoring alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The Christie NHS foundation trust UK 2020-06-30 2020-10-31 CFTSP186, NCT04397705, RECAP Phase 1 Clinical Not yet recruiting 1 4 Months 30 John Radford, Wes Dale 2020-05-25
COVID-19 PEP- High-risk Individuals in Long-term and Specialized Care - Canada Coronavirus disease 19 infection hydroxychloroquine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Lawson Health Research Institute Canada 2020-05-19 2021-04-30 9881, NCT04397328 Phase 3 Clinical Not yet recruiting 1 11 Months 336 Michael J Borrie, MB ChB 2020-05-25
A clinical study of anti-SARS-CoV-2 mRNA lipid nanoparticle vaccine for the prevention of COVID-19 infection Coronavirus disease 19 infection anti-SARS-CoV-2 mRNA lipid nanoparticle vaccine (COVID-19), CanSino Biologics/ Precision NanoSystems alone CanSino Biologics Inc, Precision NanoSystems Inc Phase Not Applicable Planned 0 2020-05-22
Efficacy and Safety of COVID-19 Convalescent Plasma Coronavirus disease 19 infection anti SARS-CoV-2 convalescent plasma alone, plasmapheresis alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institute for Transfusion Medicine of RNM University clinic of infectious diseases 2020-04-30 2021-04-29 ITM05/2020MKD, NCT04397523 Phase 2 Clinical Recruiting 0 12 Months 20 Rada Grubovic Rastvorceva, MD MSci PhD, Sedulla Useini, MD 2020-05-27
A clinical study to assess the efficacy of Axen COVID-19 RT in detecting COVID-19 infection Coronavirus disease 19 infection Axen COVID-19 RT alone Macrogen Inc Phase Not Applicable Status not specified 0 2020-05-22
A clinical study of AT-100 for the treatment of COVID-19 infection Coronavirus disease 19 infection AT-100, Airway alone Lung surfactant associated protein D modulator Airway Therapeutics LLC Phase Not Applicable Planned 0 2020-05-22
Phase I/II Clinical Trial of Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector) in Canada Coronavirus disease 19 infection Ad5-nCoV alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) CanSino Biologics Inc, Canadian Center for Vaccinology, Canadian Immunization Research Network, National Research Council of Canada Canada 2020-05-31 2021-08-31 AD5-NCOV-2020003, NCT04398147 Phase 1/Phase 2 Clinical Not yet recruiting 1 15 Months 696 Helen H Mao, PhD/MBA, Joanne M Langley, MD, Scott A Halperin, MD 2020-05-29
CCOVID-PREG: Characteristics of COVID-19 Infection Among Pregnant Women Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia RT-PCR test alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Inova Health Care Services US 2020-05-30 2021-03-17 CCOVID-PREG, NCT04398264, U20-05-4055 Phase Not Applicable Not yet recruiting 1 9 Months 100 Luis M Gomez, MD. MScE, Luis M. Gomez 2020-05-25
Inhaled NO for the Treatment of COVID-19 Caused by SARS-CoV-2 (US Trial) Coronavirus disease 19 infection LungFit system, Beyond Air alone, nitric oxide alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Beyond Air Ltd US 2020-05-18 2020-09-30 BAI_COV19_01_US, NCT04397692 Phase 2 Clinical Not yet recruiting 1 4 Months 20 Ashik Tal, MD, Enoch Bortey, Priyantha Wijewardane, MD, Vladislava Zamfirova 2020-05-29
Immunological efficacy of lactic acid bacteria for COVID-19 Coronavirus disease 19 infection lactic acid bacteria alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Takanawa Pharma KK Japan 2020-05-22 UMIN000040479 Phase Not Applicable Recruiting 1 30 Tomoka Ebisui, Tsutomu Nakamura 2020-05-28
COVID-19 Convalescent Plasma for the Treatment of Hospitalized Patients With Pneumonia Caused by SARS-CoV-2 Coronavirus disease 19 infection, Respiratory disease, Viral pneumonia COVID-19 convalescent plasma alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Pennsylvania US 2020-05-13 2020-11-13 843003 (PENNCCP-02), NCT04397757 Phase 1 Clinical Recruiting 1 6 Months 80 Julie Starr, Katharine J. Bar, Katharine J. Bar, MD 2020-05-30
A clinical trial of ADX-1612 in the treatment of patients with COVID-19 infection Coronavirus disease 19 infection ganetespib alone Hsp 90 inhibitor, Jak2 tyrosine kinase inhibitor, Kit tyrosine kinase inhibitor, STAT-3 inhibitor, STAT-5 inhibitor Aldeyra Therapeutics Inc Phase Not Applicable Planned 0 2020-05-22
COMET20d: A Study to Collect Bone Marrow for Process Development and Production of BM-MSC to Treat Severe COVID-19 Pneumonitis Coronavirus disease 19 infection, Pneumonia bone marrow harvest alone Healthy volunteers accepted, Young Adults (18-44 yrs) Cambridge Clinical Trials Unit Cambridge Cellular Therapies Laboratory, Cambridge University Hospitals NHS Foundation Trust, The Evelyn Trust UK 2020-05-31 2021-12-31 COMET20D, COMET20d, NCT04397471 Phase Not Applicable Not yet recruiting 1 19 Months 10 Andrew McCaskie, FRCS, Charles Crawley, MD, Claire Mather, BSc, Purity Bundi, BSc 2020-05-25
Clinical record investigation about ADHD children because of COVID19 Coronavirus disease 19 infection Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Chiba University Japan 2020-05-21 UMIN000040476 Phase Not Applicable Recruiting 1 10 Masaomi Iyo, Tsuyoshi Sasaki 2020-05-25
Effects of nokhod-ab on fatigue Coronavirus disease 19 infection, Fatigue nokhod-ab alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Semnan University of Medical Sciences Iran 2020-05-31 IR.SEMUMS.REC.1399.031, IRCT20200115046144N2 Phase 3 Clinical Not yet recruiting 1 40 Ali Gohari, Bahareh Ahadi, Dr. Parviz Kokhaei 2020-05-25
Mental Health Outcomes in Healthcare Workers During COVID-19 Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder online survey alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The University Health Network Sunnybrook Health Sciences Centre, University of Toronto, William Osler Health System Canada 2020-05-14 2020-06-24 3189, NCT04397848 Phase Not Applicable Recruiting 1 1 Month 1200 Laura Hawryluck, MD, Laura Hawryluck, MD, MSc, Rima Styra, MD, Rima Styra, MD, MEd 2020-05-27
HITCH: Hormonal Intervention for the Treatment in Veterans With COVID-19 Requiring Hospitalization Coronavirus disease 19 infection best supportive care (BSC) alone, degarelix alone GNRH receptor antagonist Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) VA Office of Research and Development US 2020-06-01 2020-10-01 COVID19-8900-15, HITCH, NCT04397718 Phase 2 Clinical Not yet recruiting 4 4 Months 198 Bruce Montgomery, MD, Daniel Becker, MD, Elahe Mostaghel, MD, Matthew B Rettig, MD, Matthew B. Rettig, MD, Mohammad Al-Jam, MD, Nicholas G Nickols, MD PhD, Tsay Jun-Chieh 2020-05-27
RESPOND: Pathogenesis of BTK-mediated Hyper-Inflammatory Responses in COVID-19 Coronavirus disease 19 infection bruton tyrosine kinase inhibitor therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Allergy and Infectious Diseases National Institutes of Health Clinical Center US 2020-06-03 2023-04-30 20-I-N114, 999920114, NCT04394884, RESPOND Phase Not Applicable Recruiting 3 34 Months 160 Ephraim Fuchs, M.D., Joe Roswarski, M.D., Michail S Lionakis, M.D. 2020-05-30
Combination With Alvelestat and Isotretinoin May Enhance Neutralizing Antibodies in COVID-19 Infected Patients Better Than COVID-19 Inactivated Vaccines (Antibodies) Coronavirus disease 19 infection, Respiratory failure, Respiratory tract infection alvelestat plus isotretinoin (aerosolized) Leukocyte elastase inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Kafrelsheikh University Damietta University Egypt 2020-06-30 2020-11-30 COVID-19, NCT04396067 Phase 2 Clinical Not yet recruiting 1 5 Months 360 M.Sc. Mahmoud Elkazzaz, M.Sc.in Biochemistry, M.Sc.Mahmoud Elkazzaz, Master of biochemistry 2020-05-26
Physical Activity Levels in COVID-19 Patients Admitted to Intensive Care Coronavirus disease 19 infection physiotherapy alone, rehabilitation alone, respiratory care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Birmingham NHS Foundation Trust UK 2020-03-01 2020-05-08 NCT04396197, PHYSIOCOVID-19 Phase Not Applicable Completed 1 2 Months 92 David McWilliams 2020-05-26
ALLIANCE: International ALLIANCE Study of Therapies to Prevent Progression of COVID-19 Coronavirus disease 19 infection Variable regimens including Plaquenil , azithromycin , cholecalciferol , mecobalamin , sodium ascorbate , zinc citrate Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Integrative Medicine Catholic Health Initiatives Australia 2020-05-25 2021-12-31 ALLIANCE, ALLIANCE-COVID19, NCT04395768 Phase 2 Clinical Not yet recruiting 1 19 Months 200 Karin Ried, PhD, Taufiq Binjemain, MD 2020-05-27
A Study of ResCure to Treat COVID-19 Infection Coronavirus disease 19 infection ResCure alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) ProgenaBiome Rinati Skin LLC US 2020-05-31 2021-10-31 NCT04395716, PRG-048 Phase 1 Clinical Not yet recruiting 1 17 Months 50 Jordan Daniels, MS, Sabine Hazan, MD 2020-05-26
PAIN-COVID: Early Care Program for the Management of Post-ICU Syndrome and Chronic Pain After COVID-19 Infection Anxiety disorder, Coronavirus disease 19 infection, Depression, Pain, Post traumatic stress disorder psychological intervention alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Clinic of Barcelona Spain 2020-05-25 2021-03-25 HCB/2020/0549, NCT04394169, PAIN-COVID Phase Not Applicable Not yet recruiting 1 10 Months 102 Antonio José Ojeda Niño, MD, Tomás Cuñat López, MD 2020-05-21
Patients Perspectives on Discontinuation of Their Fertility Treatment Due to the COVID-19 Pandemic Coronavirus disease 19 infection, Infertility Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Universitair Ziekenhuis Gent Belgium 2020-05-14 2020-12-31 B6702020000247, BC-07783, NCT04396210 Phase Not Applicable Recruiting 1 7 Months 2000 Frauke Vanden Meerschaut, MD, Rebecca De Beir, Msc 2020-05-22
Exercise Training and Sedentary Lifestyle on Clinical Outcomes in Patients With COVID-19 Coronavirus disease 19 infection exercise training alone Healthy volunteers accepted Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo Brazil 2020-06-01 2021-01-20 COVID-19, NCT04396353 Phase Not Applicable Not yet recruiting 1 7 Months 850 Francis S Ribeiro, PhD, Marcelo R Santos, PhD 2020-05-21
PPRI: The Professional Peer Resilience Initiative Anxiety disorder, Coronavirus disease 19 infection, Post traumatic stress disorder MinnRAP peer support program alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Minnesota US 2020-05-25 2022-05-25 NCT04396600, PPRI, STUDY00009564 Phase Not Applicable Recruiting 1 24 Months 1200 Cristina S Albott, MD, Sey Lee, BS 2020-05-21
PACCOVRA: Pediatric Acute and Critical Care COVID-19 Registry of Asia Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) KK Women's and Children's Hospital Aichi Children's Health and Medical Center, Children's Hospital of Chongqing Medical University, General Hospital H. Adam Malik, Hyogo Prefectural Kobe Children's Hospital, King Chulalongkorn Memorial Hospital, National University Hospital (Singapore) Pte Ltd, Penang General Hospital, Postgraduate Institute of Medical Education and Research, Ramathibodi Hospital, Rumah Sakit Anak dan Bunda Harapan Kita, Singapore Clinical Research Institute, St Marianna University School of Medicine, Tokyo Metropolitan Childrens Medical Center Hospital, Vicente Sotto Memorial Medical Center - Public, Zhengzhou Children's Hospital Singapore 2020-05-18 2023-12-31 2020/2094, NCT04395781, PACCOVRA Phase Not Applicable Not yet recruiting 1 43 Months 2000 Cecilia Chandra, Judith Ju Ming Wong 2020-05-27
Clinical Study for Efficacy of Anti-Corona VS2 Immunoglobulins Prepared From COVID19 Convalescent Plasma Prepared by VIPS Mini-Pool IVIG Medical Devices in Prevention of SARS-CoV-2 Infection in High Risk Groups as Well as Treatment of Early Cases of COVID19 Patients Coronavirus disease 19 infection Mini-Pool IVIG alone, anti-SARS-CoV-2 hyperimmune globulin therapy (COVID-19), Assiut University alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Assiut University Egypt 2020-06-01 2021-01-01 MINI-POOLED IVIG IN COVID19, NCT04383548 Phase 2 Clinical Not yet recruiting 1 7 Months 100 Alia M Hussein, professor, Alshaimaa M Selim, specialist, Azza M Ez-Eldin, professor, Magdy El Ekiaby, Doctor, Maha A Mohamed, professor 2020-05-28
SAVE: A Phase II Study of the C3 Inhibitor AMY-101 in Patients With ARDS Due to COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome AMY-101 alone Complement C3 inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Amyndas Pharmaceuticals 2020-07-31 2021-03-31 AMY-101_SAVE, NCT04395456, SAVE Phase 2 Clinical Not yet recruiting 0 8 Months 144 2020-05-21
An Expanded Access Study to Provide at Home Subcutaneous Administration of Pertuzumab and Trastuzumab Fixed-Dose Combination (PH FDC SC) for Patients With HER2-Positive Breast Cancer During the COVID-19 Pandemic Breast tumor, Coronavirus disease 19 infection pertuzumab + trastuzumab (sc Enhanze, breast cancer), Roche alone Erbb2 tyrosine kinase receptor inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Genentech Inc US AL42478, NCT04395508 Phase Not Applicable Recruiting 9 Clinical Trials 2020-05-22
Home Usability Study of the SARS-CoV-2 (COVID-19)Test Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Exact Sciences Corp US 2020-05-18 2020-06-30 2020-06, NCT04395391 Phase Not Applicable No longer recruiting 1 1 Month 30 Steven Shak 2020-05-29
The effect of hot cupping on corona symptoms Coronavirus disease 19 infection hot cupping alone, azithromycin plus lopinavir + ritonavir HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Mazandaran University of Medical Sciences Iran 2020-05-04 IR.MAZUMS.REC.1399.162, IRCT20131129015584N3 Phase 2 Clinical Recruiting 1 68 Assie Jokar, Dr Assie Jokar, Dr Majid Saidi 2020-05-22
TAC-COVID19: Lung CT Scan Analysis of SARS-CoV2 Induced Lung Injury Coronavirus disease 19 infection, Lung injury, Respiratory distress syndrome, Respiratory insufficiency, Viral pneumonia CT scan alone, deep learning algorithm-artificial intelligence technology alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Milano-Bicocca San Marino, Italy 2020-04-15 2020-10-15 NCT04395482, TAC-COVID19, TAC-COVID19 Phase Not Applicable Recruiting 8 6 Months 500 Emanuele Rezoagli, Giacomo Bellani, Giovanni Vitale, Giuseppe Nardi, Luca Lorini, Mario Tavola, Massimo Arlotti, Matteo Subert, Savino Spadaro 2020-05-27
A phase II study of R-107 for the treatment of severe acute respiratory syndrome in COVID-19 Coronavirus disease 19 infection, SARS coronavirus infection R-107 alone Massachusetts General Hospital Phase 2 Clinical Planned 0 2020-05-21
Dexamethasone for COVID-19 Related ARDS: a Multicenter, Randomized Clinical Trial Coronavirus disease 19 infection, Respiratory distress syndrome dexamethasone alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centro de Educación Medica e Investigaciones Clínicas Norberto Quirno Argentina 2020-05-21 2021-01-31 1264, NCT04395105 Phase 3 Clinical Recruiting 1 8 Months 284 Ignacio Bonelli, MD, Luis P Maskin, MD, Pablo O Rodriguez, MD, Stella Zarza, SC 2020-05-26
Sleep Quality in Healthcare Personnel During COVID-19 Coronavirus disease 19 infection web based online survey alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assiut University Egypt 2020-03-30 2020-05-16 ASSIUTU14, NCT04395300 Phase Not Applicable Completed 1 1 Month 143 Aliae AR Mohamed Hussein 2020-05-26
COVIDIV: Collateral Damage From the COVID-19 Pandemic Observed in Patients Treated With Intravitreal Injections (IVT) of Anti-angiogenic Agents Coronavirus disease 19 infection, Diabetic macular edema, Retinal venous occlusion, Wet age related macular degeneration Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fondation Ophtalmologique Adolf De Rothschild France 2020-05-31 2021-12-31 COVIDIV, MMT_2020_15, NCT04395859 Phase Not Applicable Not yet recruiting 4 19 Months 1500 Amélie YAVCHITZ, MD, Benjamin WOLFF, MD, Flore DE BATS, MD, Martine MAUGET FAYSSE, Martine MAUGET FAYSSE, MD, Ramin TADAYONI, MD 2020-05-22
Sexual Function During COVID-19 Pandemic Coronavirus disease 19 infection, Sexual dysfunction electronic questionnaire alone Healthy volunteers accepted, Young Adults (18-44 yrs) Assiut University Egypt 2020-06-01 2020-08-31 NCT04395885, SFCOV Phase Not Applicable Not yet recruiting 1 3 Months 120 Ahmed Mohamed Abbas 2020-05-22
A clinical study of SARS-CoV-2 vaccine (VLP, COVID-19) for the potential prevention of SARS-CoV-2 infection (COVID-19) Coronavirus disease 19 infection SARS-CoV-2 vaccine (VLP, COVID-19), Medicago alone Medicago Inc Canada 2020-08-31 Phase Not Applicable Planned 1 2020-05-21
COVID HELMET: Helmet CPAP Versus HFNC in COVID-19 Coronavirus disease 19 infection, Respiratory failure CaStar hood (Bio-Med Devices) alone, Helmet continuous positive airway pressure therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Lund Region Skane Sweden 2020-05-31 2021-05-31 COVID HELMET, COVID HELMET, NCT04395807 Phase Not Applicable Not yet recruiting 1 12 Months 120 Jonas Tverring, MD, Niklas Nielsen, MD PhD 2020-05-22
Psychiatric Consultation for COVID-19 Patients Coronavirus disease 19 infection, Psychiatric disorder psychiatric counseling alone Daegu Catholic University medical center South Korea 2020-05-28 2020-12-31 CR-20-062, NCT04395872 Phase Not Applicable Not yet recruiting 1 7 Months 54 Jonghun Lee, M.D., ph.D., geunhui Won, M.D. 2020-05-28
TMF-COVID-19: Maternal-fetal Transmission of SARS-Cov-2 Coronavirus disease 19 infection RT-PCR SARS-Cov-2 test alone, blood sampling alone, electron microscopy alone, serology test alone, vaginal swab sampling alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Centre Hospitalier Regional D'Orleans France 2020-05-05 2021-05-31 CHRO-2020-10, NCT04395924, TMF-COVID-19 Phase Not Applicable Recruiting 1 12 Months 50 Aurélie DESPUJOLS, Elodie POUGOUE TOUKO, Souhail ALOUINI, Dr 2020-05-29
A clinical study of S-309 for the potential treatment and/or prevention of SARS-CoV-2 infection (COVID-19) Coronavirus disease 19 infection SARS-COV-2 targeting human monoclonal antibodies (COVID-19), Vir Biotechnology/ WuXi Biologics alone COVID19 Spike glycoprotein inhibitor Vir Biotechnology Inc Phase Not Applicable Planned 0 2020-05-21
Convalescent Plasma Compared to Anti-COVID-19 Human Immunoglobulin and Standard Treatment (TE) in Hospitalized Patients Coronavirus disease 19 infection COVID-19 convalescent plasma alone, anti-COVID-19 human immunoglobulin alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Lifefactors Zona Franca, SAS 2020-06-30 2021-06-30 LFCOLCOVID-19-001, NCT04395170 Phase 2/Phase 3 Clinical Not yet recruiting 0 12 Months 75 Santiago Jaramillo 2020-05-22
TMX COVID: 1,3,7-Trimethylxanthine as a Treatment of COVID-19: Results of a Controlled Study Coronavirus disease 19 infection coffee containing 1,3,7-trimethylxanthine intake alone, tea and hot chocolate with milk intake alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire De Poitiers Etablissement D’Hospitalisation 2020-05-31 2020-12-31 NCT04395742, TMX COVID, TMX COVID Phase Not Applicable Not yet recruiting 0 7 Months 93 Alexandre BLEIBTREU, Paul ROBLOT 2020-05-22
Impact of COVID-19 on Psychological Status in Case of IVF Interrupted or Postponed Coronavirus disease 19 infection, Female infertility Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) IRCCS AOU San Martino – IST Italy 2020-04-01 2020-05-15 COVID-19-NOIVF, NCT04395755 Phase Not Applicable Completed 1 1 Month 503 Fabio Barra 2020-05-22
ACOVID: Arrhythmias in Patients With COVID-19 Coronavirus disease 19 infection, Heart arrhythmia C3+ Holter Monitor alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Herlev and Gentofte Hospital, Denmark Denmark 2020-04-16 2021-04-01 ACOVID, H-20021500, NCT04395664 Phase Not Applicable Recruiting 1 11 Months 1000 Morten Kjøbek Lamberts, MD, PhD, Morten Kjøbæk Lamberts, MD, PhD, Morten Lamberts 2020-05-22
A phase IIb/III trial to evaluate aviptadil in COVID-19 patients with Acute respiratory distress syndrome Coronavirus disease 19 infection, Respiratory distress syndrome aviptadil (inhaled, sarcoidosis/acute lung injury/acute respiratory distress syndrome associated COVID-19), Relief Therapeutics Holding alone Adrenergic receptor antagonist, VIP receptor agonist University of California Irvine US Phase 2/Phase 3 Clinical Planned 1 30 2020-05-21
Disguise: SARS-CoV-2 Disguise Study Coronavirus disease 19 infection biological testing alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Meshalkin Research Institute of Pathology of Circulation Russian Federation 2020-05-07 2020-11-30 CS-COVID-19, Disguise, NCT04395794 Phase Not Applicable Recruiting 1 6 Months 900 Alexander B Romanov, PhD, Denis V Losik, PhD, Dmitry N Ponomarev, PhD, Igor L Mikheenko, Nurlan A Elemesov, Vladimir V Beloborodov, Vladimir V Lomivorotov, PhD 2020-05-22
A randomized, double-blind, placebo-controlled, Phase II clinical trial designed to determine the clinical efficacy of chloroquine phosphate (CQ) in preventing coronavirus disease 2019 (COVID-19) in healthcare workers with moderate to high risk of exposure to SARS-CoV-2 Coronavirus disease 19 infection chloroquine phosphate alone Columbia University Rising Pharmaceuticals Inc US Phase 2 Clinical Status not specified 1 350 2020-05-21
ECHO: National Survey on the Lockdown of Children With Disabilities Coronavirus disease 19 infection, Movement disorder Healthy volunteers accepted, Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) University Hospital, Brest France 2020-04-07 2020-05-11 CHRU DE BREST ECHO, ECHO, NCT04395833 Phase Not Applicable Completed 1 1 Month 2500 2020-05-22
Safety and Efficacy of AT-527 in Subjects With Moderate Coronavirus Disease (COVID-19) Coronavirus disease 19 infection AT-527 alone, local supportive standard of care alone Hepatitis C virus NS5B polymerase inhibitor Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Atea Pharmaceuticals Inc US 2020-05-31 2020-08-31 AT-03A-001, NCT04396106 Phase 2 Clinical Not yet recruiting 10 3 Months 180 Clinical Trials Administrator 2020-05-26
The effect of omega-3 supplementation in COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia omega-3 (Omid persina damavand company) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sabzevar University of Medical Sciences Iran 2020-06-04 IR.MEDSAB.REC.1399.054, IRCT20151226025699N3 Phase Not Applicable Not yet recruiting 1 50 Dr. Alireza Moslem, Saeid Doaei, Siamak Rimaz 2020-05-22
A clinical study to assess virosome-based Covid-19 vaccine candidate for the potential treatment of COVID-19 Coronavirus disease 19 infection SARS-CoV vaccine (protein-subunit, virosome encapsulated, COVID-19), Baylor College of Medicine/Mymetics alone COVID19 Spike glycoprotein modulator Mymetics Corp Baylor College of Medicine Phase Not Applicable Planned 0 2020-05-29
Prone Positioning and High-flow Nasal Cannula in COVID-19 Induced ARDS Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia Prone position alone, high-flow nasal cannula alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Vall D'Hebron Spain 2020-05-01 2021-06-30 NCT04391140, PR(AG)198/2020 Phase Not Applicable Recruiting 1 14 Months 248 Cesar Laborda, MD, Jordi Riera, MD PhD, Judit Sacanell, MD, Marina García-de-Acilu, MD, Oriol Roca, MD PhD 2020-05-22
COVID-AKI: Urinary Biomarkers for AKI Diagnosis in Patients With SARS-CoV-2 (COVID-19) Coronavirus disease 19 infection, Renal injury urinary sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Montpellier France 2020-03-01 2020-06-30 COVID-AKI, NCT04393428, RECHMPL20_0294 Phase Not Applicable Recruiting 1 4 Months 100 Romaric Larcher, MD, PharmD, Romaric Larcher, MD, PharmD, MSc 2020-05-22
Clinical Use of Stem Cells for the Treatment of COVID-19 Coronavirus disease 19 infection, Viral pneumonia allogenic umbilical cord derived-mesenchymal stem cells alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Bakirkoy Dr. Sadi Konuk Research and Training Hospital Istinye Universitesi, Liv Hospital (Ulus) Turkey 2020-04-01 2020-09-30 BAK. SADI KONUK-ISTINYE UNI., NCT04392778 Phase 1/Phase 2 Clinical Recruiting 2 6 Months 30 Erdal Karaoz, Prof.Dr., Gokhan T Adas, Prof.Dr. 2020-05-25
TSUNAMI: Transfusion of Convalescent Plasma for the Early Treatment of Patients With COVID-19 Coronavirus disease 19 infection, Viral pneumonia convalescent plasma alone, rescue therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Azienda Ospedaliero, Universitaria Pisana Italy 2020-05-01 2020-10-30 NCT04393727, TSUNAMI, TSUNAMI Phase 2 Clinical Recruiting 1 5 Months 126 Francesco Menichetti, Marco Falcone 2020-05-22
A Randomized Study to Assess the Effect of IFN-alpha2b in Patients With COVID-19 Coronavirus disease 19 infection interferon-alpha2b (inhalant aerosol, COVID-19), The University Health Network alone Interferon alpha 2 ligand modulator The University Health Network Phase Not Applicable Planned 0 2020-05-26
RHUMACOVID: Drug Management of Rheumatoid Arthritis in COVID-19 Context: Impact on Therapeutic De-escalation Coronavirus disease 19 infection, Rheumatoid arthritis DMARD therapy management alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Brest France 2020-04-23 2020-05-23 NCT04393233, RHUMACOVID, RHUMACOVID (29BRC20.0110) Phase Not Applicable Recruiting 1 1 Month 300 Dewi GUELLEC, Dewi Guellec, Valerie Devauchelle 2020-05-21
An Observational Study to Assess the Incidental Findings Suggestive of COVID-19 in Asymptomatic Patients Undergoing Nuclear Medicine Procedures in a High-Prevalence Region Coronavirus disease 19 infection 131-iodine alone, 18F-FDG alone, PET/CT alone, SPECT/CT alone Universita degli Studi di Brescia Italy Phase Not Applicable Status not specified 1 77 2020-05-21
Impact of an Intensified Thromboprofylaxis Protocol in COVID-19 Coronavirus disease 19 infection, Deep vein thrombosis, Liver failure, Renal failure low molecular weight heparin alone, thromboprophylaxis protocol alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Jessa Hospital Belgium 2020-05-04 2020-05-15 JESSA-20.48, NCT04394000 Phase Not Applicable Completed 1 72 2020-05-22
Impact of Covid-19 Pandemic on Depression and Quality of Life Coronavirus disease 19 infection, Depression Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Okan University Yuksek İhtisas University Turkey 2020-05-06 2020-05-18 56665618-204.01.07, NCT04394078 Phase Not Applicable Recruiting 1 500 Begum Okudan 2020-05-22
Low Dose Radiation Therapy for Covid-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia low dose radiation therapy (70 cGy) alone, standard therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences India 2020-06-30 2021-06-30 COVID-AIIMS, NCT04394793 Phase Not Applicable Not yet recruiting 1 12 Months 10 Daya Nand Sharma, MD, Randeep Guleria, MD, Supriya Mallick, MD 2020-05-28
POCUS VTE COVID: Hocus POCUS: a tool for increasing the efficiency of diagnosing venous thromboembolic disease in critically ill COVID-19 patients? Coronavirus disease 19 infection, Thromboembolism Hocus POCUS alone, point-of-care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitair Medisch Centrum Utrecht Netherlands 2020-05-15 2021-01-01 NL8625, POCUS VTE COVID Phase Not Applicable Recruiting 1 7 Months 50 Dirk Tjwa 2020-05-29
Association of BMI with COVID-19 incidence and severity Coronavirus disease 19 infection Leiden University Medical Center Netherlands 2020-03-01 2020-09-01 NL8627 Phase Not Applicable Not yet recruiting 1 6 Months 200 Rutger Middelburg 2020-05-29
SCOPE: Silymarin in COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia silymarin alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cairo University Egypt 2020-06-01 2020-09-30 CAIROU COVID-19 STUDY GROUP, NCT04394208, SCOPE Phase 3 Clinical Not yet recruiting 1 4 Months 50 Khaled Mohammed Korany Salem, Khaled Salem, MSc, Khaled Salem, Msc, Mostafa Alfishawy, Consultant, Mostafa Alfishawy, MD 2020-05-20
COVID 19 - What Families Think and Do? A Survey for Families Visiting the Pediatric Emergency Department Coronavirus disease 19 infection Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) BC Children's Hospital, St Marianna University School of Medicine, University of British Columbia North America, Japan, Europe 2020-05-22 UMIN000040451 Phase Not Applicable Not yet recruiting 1 500 Naoki Shimizu, Tomohiro Katsuta 2020-05-23
Investigation of the effect of intravenous vitamin C on definite patients with coronavirus pneumonia Coronavirus disease 19 infection Variable regimens including azithromycin , interferon beta , lopinavir + ritonavir , meropenem , vancomycin , vitamin C, Daroupakhsh Company HIV protease inhibitor, Penicillin binding protein inhibitor, Peptidoglycan recognition protein inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shaheed Beheshti Medical University Iran 2020-04-08 IR.SBMU.RETECH.REC.1399.067, IRCT20200516047468N1 Phase 2/Phase 3 Clinical No longer recruiting 1 50 Afshin Zarghi, Hamideh Moradi Shahr Babak 2020-05-22
Combination therapy of Favipiravir and Nafamostat Mesilate in Patients with COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia standard treatment alone, favipiravir plus nafamostat Mesilate RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) The University of Tokyo Hospital Japan 2020-05-01 jRCTs031200026 Phase 2 Clinical Recruiting 1 160 Kyoji Moriya 2020-05-26
Amotosalen-Ultraviolet A Pathogen-Inactivated Convalescent Plasma in Addition to Best Supportive Care and Antiviral Therapy on Clinical Deterioration in Adults Presenting With Moderate to Severe COVID-19 Coronavirus disease 19 infection, SARS coronavirus infection INTERCEPT Blood System alone, convalescent plasma alone, standard of care alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) University Hospital Basel Switzerland 2020-03-31 2020-06-30 NCT04389944, REQ-2020-00508, ME20KHANNA2 Phase Not Applicable Recruiting 1 3 Months 15 Andreas Buser, Prof. Dr. MD, Andreas Buser, Prof. Dr. med., Maja Weisser, Prof. Dr. med., Manuel Battegay, Prof. Dr. med., Nina Khanna, Prof. Dr. MD, Nina Khanna, Prof. Dr. med 2020-05-20
ULTRA-COVID: Ultra Low Doses of Therapy With Radiation Applicated to COVID-19 Coronavirus disease 19 infection, Inflammatory disease, Viral pneumonia Ventimask alone, nasal cannula alone, oxygen therapy alone, ultra-low-dose radiotherapy (0.8 Gy) alone, Variable regimens including Urbason , azithromycin , hydroxychloroquine (Dolquine) , lopinavir + ritonavir , low molecular weight heparin , piperacillin + tazobactam , tocilizumab HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundacion GenesisCare Hospital La Milagrosa, Hospital Vithas Valencia Consuelo Spain 2020-04-21 2021-04-21 20.4.1597-GHM, NCT04394182, ULTRA-COVID Phase 2 Clinical Recruiting 2 12 Months 15 Elena Moreno Olmedo, MD, Escarlata López Ramírez, MD, PhD, Luis María Larrea Rabassa, MD, Manuel Pérez Fernández, MD 2020-05-20
New SARS-CoV-2 detection system Coronavirus disease 19 infection SARS-CoV-2 detection system alone Kawasaki Rinko General Hospital Japan 2020-04-30 jRCT1032200025 Phase Not Applicable Not yet recruiting 1 50 Watanabe Yoshiyuki 2020-05-26
Long Term Functional Outcomes of COVID-19 Patients Treated by Rehabilitation Services viaTelehealth Coronavirus disease 19 infection, Viral pneumonia rehabilitation program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Missouri US 2020-05-19 2022-04-19 COVID19RECOVERY, NCT04385901 Phase Not Applicable Not yet recruiting 1 23 Months 72 Chelsea Harrison, DPT, Jennifer Y Stone, Jennifer Y Stone, PT, DPT, OCS 2020-05-22
Mir-Age: ABX-464 in Treating Inflammation and Preventing Acute Respiratory Failure in Patients With COVID-19 Coronavirus disease 19 infection, Inflammatory disease, Respiratory failure ABX-464 alone, standard of care alone Rev protein modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Abivax SA Bpifrance France, Europe 2020-05-01 2021-04-30 ABX464-401, Mir-Age, NCT04393038 Phase 2/Phase 3 Clinical Recruiting 1 12 Months 1034 Anais Vissian, Eric CUA, MD, Paul GINESTE 2020-05-20
Using PRP and Cord Blood in Treatment of Covid-19 Coronavirus disease 19 infection cord blood stem cells alone, platelet rich plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Aljazeera Hospital Egypt 2020-05-25 2020-08-01 COVID -19, NCT04393415 Phase 2 Clinical Not yet recruiting 1 2 Months 100 Mahmoud Alalfy, PhD 2020-05-27
Efficacy of Kelofan syrup on COVID-19 Coronavirus disease 19 infection Kelofan syrup alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ardabil University of Medical Sciences Iran 2020-05-17 2020-07-05 IR.ARUMS.REC.1399.009, IRCT20200405046960N2 Phase 2/Phase 3 Clinical Recruiting 1 1 Month 60 Ramin Nasimi Doost Azgomi 2020-05-21
Longitudinal, COVID-19 Cohort Study Coronavirus disease 19 infection, Respiratory failure Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Vermont US 2020-04-16 2023-05-31 CHRMS 16-540, NCT04393155 Phase Not Applicable Recruiting 2 37 Months 225 Arooj Fatima, Dale Needham, MD, PhD, Renee D Stapleton, MD, PhD, Sara S Ardren, PA 2020-05-21
COVID19IF: Imaging Feature of SARS-CoV2 Infection Coronavirus disease 19 infection IRCCS San Raffaele Italy 2020-04-16 2020-10-01 COVID-19 IF, COVID19IF, NCT04394026 Phase Not Applicable Recruiting 1 5 Months 500 Carlo Martinenghi, MD, Francesco De Cobelli, Francesco De Cobelli, MD, Stephanie Steidler, PhD 2020-05-20
Serological Testing of Household Contacts of Confirmed Cases of COVID-19 Coronavirus disease 19 infection COVID-19 IgM/IgG test kit (Singclean) alone, serological test alone Healthy volunteers accepted, Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Universitario Dr. Jose E. Gonzalez Mexico 2020-05-05 2020-06-01 IF20-00004, NCT04393142 Phase Not Applicable Recruiting 1 92 Adrian Camacho, PhD, Adrian Camacho-Ortiz, MD, Adrian Camacho-Ortiz, PhD, Eduardo Pérez Alba, MD, Edurdo Pérez Alba, MD, Gloria Mayela Aguirre García, MD, Jaime Eugenio Espinosa Mora, MD, Laura Marina Nuzzolo Shihadeh, MD 2020-05-21
COVID_coagulation: Investigation of the predictive value of coagulation parameters for the course of disease in COVID-19 patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Johann Wolfgang Goethe-Universitat Frankfurt am Main Germany 2020-04-08 20-627, COVID_coagulation, DRKS00021574 Phase Not Applicable Recruiting 1 1000 Wolfgang Prof Miesbach 2020-05-22
DOCOV: Description of Ophthalmologic Injuries in Intensive Care During the SARS-CoV2 Epidemic - COVID19 Coronavirus disease 19 infection, Ocular injury Direct exam alone, Shirmer test Retinophotography alone, Slit lamp exam alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fondation Ophtalmologique Adolf De Rothschild France 2020-04-27 2020-10-31 DOCOV, JDS_2020_13, NCT04385810 Phase Not Applicable Recruiting 1 6 Months 100 Amélie YAVCHITZ, MD, Jean Michel DEVYS, MD, Sophie STEPHAN, MD 2020-05-22
LUS-COVID19: Lung Ultrasound Score in Covid-19 Infectious Disease in Critical Care Coronavirus disease 19 infection, Respiratory distress syndrome lung ultrasound (LUS) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire De Nice France 2020-03-20 2020-12-31 20REAMEDCOVID03, LUS-COVID19, NCT04393402 Phase Not Applicable Recruiting 1 9 Months 14 Jean DELLAMONICA, Jean DELLAMONICA, MD, PhD, Romain LOMBARDI 2020-05-21
Trial of Imatinib for Hospitalized Adults With COVID-19 Coronavirus disease 19 infection imatinib alone Abl tyrosine kinase inhibitor, Bcr protein inhibitor, Kit tyrosine kinase inhibitor, PDGF receptor antagonist, Signal transduction inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Maryland US 2020-05-20 2023-06-01 2038GCCC, NCT04394416 Phase 3 Clinical Not yet recruiting 1 36 Months 204 Ashkan Emadi, MD, PhD, Monica Estrada 2020-05-21
CORMOR: Blood Ozonization in Patients With SARS-CoV-2 Respiratory Failure Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure, Respiratory insufficiency, Viral pneumonia Blood Ozonization alone, Variable regimens including Hydroxychloroquine , darunavir + cobicistat (fixed dose, HIV infection), Janssen R&D/ Gilead , lopinavir + ritonavir Cytochrome P450 3 inhibitor, HIV protease inhibitor, HIV-1 protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Azienda Universitaria Integrata di Udine Azienda Ospedaliera Ordine Mauriziano di Torino, Azienda Sanitaria Locale di Vercelli, Celio Military Hospital, Fondazione Toscana Gabriele Monasterio, Ospedale Civile S. Liberatore di Atri, Ospedale Civile di Lucca, Ospedale di Siracusa, University of Siena Italy 2020-04-08 2020-10-08 CIG: Z7C2CA5837, CORMOR, NCT04388514 Phase Not Applicable Recruiting 1 6 Months 90 Amato De Monte, Amato De Monte, MD, Carlo Tascini, MD, Emanuela Sozio, MD 2020-05-22
PROVENT-COVID: Accelerated Prone Position Ventilation of Patients With COVID-19 Coronavirus disease 19 infection Prone position ventilation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Nordsjaellands Hospital Denmark 2020-05-11 2020-12-31 H-20027361, NCT04384900, PROVENT-COVID Phase Not Applicable Recruiting 1 7 Months 150 Morten H Bestle, MD, PhD, Morten H Bestle, MD,PhD, Theis S Itenov, MD, PhD, Theis S Itenov, MD,PhD 2020-05-21
COVID-PRONE: Prone Positioning for Patients on General Medical Wards With COVID19 Coronavirus disease 19 infection Prone positioning alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) St Michaels Hospital Sinai Health System, Sunnybrook Health Sciences Centre, The University Health Network, Toronto General Hospital Canada 2020-05-15 2020-12-11 2020-1, COVID-PRONE, NCT04383613 Phase Not Applicable Recruiting 5 6 Months 350 Amol Verma, MD, MPhil, Fahad Razak, MD, MSc, Michael Fralick, MD, PhD 2020-05-22
CoVInnate: Role of Inflammasomes in COVID-19 Disease Coronavirus disease 19 infection DNA analysis alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire De Nice France 2020-05-11 2021-06-12 20-PP-07, CoVInnate, NCT04385017 Phase Not Applicable Recruiting 2 13 Months 40 COURJON JOHAN, PH, COURJON JOHAN, Ph, COURJON Johan, COURJON Johan, Ph, CUA ERIC, PH, Cua Eric, Ph, ROBERT Alexandre, ROBERT Alexandre, Ph 2020-05-21
Seroprevalence of SARS CoV 2 Antibodies in Previously Undiagnosed Healthcare Workers Coronavirus disease 19 infection Serologic testing alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mayo Clinic Foundation US 2020-05-06 2020-06-12 20-004054, NCT04383587 Phase Not Applicable Recruiting 1 1 Month 300 Mark Parkulo, MD 2020-05-21
COVIDVIT: Do Vitamin D Levels Really Correlate With Disease Severity in COVID-19 Patients? Coronavirus disease 19 infection vitamin D alone Bursa City Hospital Turkey 2020-05-01 2020-06-30 1, COVIDVIT, NCT04394390 Phase Not Applicable Recruiting 1 2 Months 100 Taner Dandinoğlu 2020-05-22
Convalescent Plasma and Placebo for the Treatment of COVID-19 Severe Pneumonia Coronavirus disease 19 infection, Viral pneumonia Convalescent SARS COVID-19 plasma alone, standard care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Italiano de Buenos Aires Argentina 2020-05-15 2020-08-20 5565, NCT04383535 Phase Not Applicable Not yet recruiting 7 3 Months 333 Claudia Salgueira, Esteban Nannini, Fernando Palizas, Florencia Otermin, Francisco Klein, Gustavo Lopardo, Javier Altclas, Javier Sarro, Karina Rainiero, Laura Barcelona, Liliana Sarro, Marcelo Losso, Mariangeles Fenes, Matias Lahitte, Nadia Ahmed, Nora A Fuentes, MD, Pablo Gutierrez, Ricardo Valentini, Santiago Ramirez Borga, Ventura Simonovich, MD, Waldo H Belloso, PhD 2020-05-22
SINUS WASH: Pilot Study in Adults Testing Positive for COVID-19 Coronavirus disease 19 infection Betadine alone, Umotif app alone, Videne alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hampshire Hospitals NHS Foundation Trust UK 2020-05-31 2020-08-31 2020-001721-31, NCT04393792, SINUS WASH, SPON-AK-0420 Phase 2 Clinical Recruiting 1 3 Months 40 Afroze Khan, MBBS MRCS, Chief Investigator, Matthew Dryden 2020-05-22
TACTIC-E: Multi-arm Therapeutic Study in Pre-ICU Patients Admitted With Covid-19 - Experimental Drugs and Mechanisms Coronavirus disease 19 infection, Multiple organ failure EDP-1815 alone, standard of care alone, ambrisentan plus dapagliflozin propanediol Endothelin ET-A receptor antagonist, Sodium glucose transporter-2 inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cambridge University Hospitals NHS Foundation Trust UK 2020-05-20 2021-05-20 NCT04393246, TACTIC-E, TACTIC-E Phase 2/Phase 3 Clinical Not yet recruiting 1 12 Months 1407 Joseph Cheriyan, MBChB MA FRCP, Sonakshi Kadyan, BTech MRes 2020-05-21
CLARITY: Controlled evaluation of Angiotensin Receptor Blockers for COVID-19 respiratory Disease Coronavirus disease 19 infection, Respiratory disease candesartan alone, eprosartan alone, irbesartan alone, losartan alone, olmesartan medoxomil alone, standard care alone, telmisartan alone, valsartan alone Angiotensin I receptor antagonist, Angiotensin II AT-1 receptor antagonist, Angiotensin II receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The George Institute for Global Health Australia 2020-05-20 2021-04-30 11052020, CLARITY, NCT04394117 Phase 4 Clinical Not yet recruiting 4 11 Months 605 Arlen Wilcox, Carol Pollock, Greg Fox, Louisa Sukkar, Meg Jardine 2020-05-21
HETHICO: Heparins for Thromboprophylaxis in COVID-19 Patients: HETHICO Study in Veneto Coronavirus disease 19 infection, Thrombosis enoxaparin sodium alone Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Quovadis Associazione University of Padua Italy 2020-06-30 2020-12-31 HETHICO, HETHICO, NCT04393805 Phase Not Applicable Not yet recruiting 1 6 Months 877 Paolo Simioni, Prof. 2020-05-22
First Level Socio-geriatric Evaluation: ESOGER Databank Coronavirus disease 19 infection, Muscle weakness ESOGER questionnaire alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sir Mortimer B Davis Jewish General Hospital Canada 2020-04-20 2021-04-19 MP-05-2021-2308, NCT04393649 Phase Not Applicable Recruiting 1 12 Months 20000 Kevin Galery, Olivier Beauchet, MD 2020-05-21
KoCo19: Prospective COVID-19 Cohort Munich Coronavirus disease 19 infection Klinikum der Universitat Muenchen Deutsche Forschungsgemeinschaft (DFG), German Federal Ministry of Education and Research, Staatsministerium fur Wissenschaft und Kunst Germany 2020-04-07 20-275, DRKS00021698, KoCo19 Phase Not Applicable Recruiting 1 6000 Michael Hoelscher, Michael Pritsch 2020-05-21
FACCT: Favipiravir and Hydroxychloroquine Combination Therapy Coronavirus disease 19 infection favipiravir plus hydroxychloroquine RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) King Abdullah International Medical Research Center Saudi Arabia 2020-05-31 2021-11-30 FACCT, NCT04392973, RC20/174 Phase 2 Clinical Not yet recruiting 1 18 Months 520 Majed Al Jeraisy, Mohammad Bosaeed, Mohammad Bosaeed, MD 2020-05-21
A trial to assess IBIO-200 for potential treatment of COVID-19 Coronavirus disease 19 infection IBIO-200 alone iBio Inc Phase Not Applicable Planned 0 2020-05-20
Telepharmacy, inhaler technique, satisfaction, COVID-19 Coronavirus disease 19 infection telepharmacy counseling alone Hospital Sungai Buloh Malaysia 2020-05-15 2020-09-30 54975, NMRR-20-951-54975 Phase Not Applicable Status not specified 1 4 Months MS KALAIVANI A/P SUBRAMANIAM 2020-05-21
At-Home COVID-19 Antibody Test Usability Assessment and Behavior Change Study Coronavirus disease 19 infection Premier Biotech COVID-19 IgG/IgM Rapid test Cassette alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) ProofPilot Radish Health, Sanesco Bv US 2020-04-05 2020-08-29 2458, NCT04393961 Phase Not Applicable Recruiting 1 4 Months 600 Matthew Amsden, Viral Patel, MD 2020-05-29
TubeObs-Covid: Endotracheal Tube Obstruction in COVID-19 Patients Requiring Mechanical Ventilation Coronavirus disease 19 infection mechanical ventilation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopitaux Universitaires de Strasbourg France 2020-04-24 2020-06-24 7803, NCT04394429, TubeObs-Covid Phase Not Applicable Recruiting 1 2 Months 184 Bob HEGER, MD, Saïd CHAYER, PhD, HDR 2020-05-21
COVID-Net Validation Coronavirus disease 19 infection Selayang Hospital Malaysia 2020-05-15 2020-12-14 54941, NMRR-20-949-54941 Phase Not Applicable Status not specified 1 7 Months Hafiz Git Kim Ann 2020-05-21
A Exploratory, Non-randomized Study to Assess the Effect of IFN-alpha2b in Patients With COVID-19 Coronavirus disease 19 infection interferon-alpha2b (inhalant aerosol, COVID-19), The University Health Network alone Interferon alpha 2 ligand modulator The University Health Network China Phase 2 Clinical Recruiting 1 77 2020-05-26
Lung Irradiation for COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia bilateral lung irradiation (100 cGy) alone, single lung irradiation (100 cGy) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Brigham & Women's Hospital US 2020-05-31 2020-11-30 2020P001494, NCT04393948 Phase Not Applicable Not yet recruiting 1 6 Months 36 David Kozono, MD, PhD, Thomas Johnson, MS 2020-05-21
COALIZAO ACTION: Full Anticoagulation Versus Prophylaxis in COVID-19 Blood clotting disorder, Coronavirus disease 19 infection, Thromboembolism azithromycin alone, enoxaparin sodium alone, rivaroxaban alone, routine full anticoagulation strategy therapy alone, unfractionated heparin alone, Variable regimens including azithromycin , enoxaparin sodium , rivaroxaban , unfractionated heparin Factor Xa antagonist, Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Brazilian Clinical Research Institute Beneficencia Portuguesa of Sao Paulo, Brazilian Research In Intensive Care Network, Hospital Alemao Oswaldo Cruz, Hospital Of Syrian Lebanese Itatiba S/C Ltd, Hospital do Coracao, Instituto de Educação e Pesquisa do Hospital Moinhos de Vento, Sociedade Beneficente Israelita Brasileira Hospital Albert Einsten Brazil 2020-05-31 2020-12-31 002/2020, COALIZAO ACTION, NCT04394377 Phase 4 Clinical Not yet recruiting 1 7 Months 600 Renato D. Lopes, MD, PhD 2020-05-26
COVIDsFlt1: sFlt1: a Biomarker of Organ Dysfunction in Critically-ill Patients With COVID-19? Coronavirus disease 19 infection, Multiple organ failure, Vascular disease Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire de Reims France 2020-03-25 2020-09-01 COVIDsFlt1, NCT04394195, PO20043* Phase Not Applicable Recruiting 1 5 Months 200 Damien JOLLY 2020-05-21
Efficacy of Ivermectin in COVID-19 Coronavirus disease 19 infection chloroquine plus ivermectin Chloride channel modulator Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Combined Military Hospital, Pakistan Pakistan 2020-04-15 2020-07-31 IVE-COV, NCT04392713 Phase 2 Clinical Recruiting 1 3 Months 100 Asma Asghar, Asma Asghar, FCPS MED, Karamat Hu Bukhari, FCPS MED, Najma Parveen, FCPS MED, Najma Parveen, FCPS med 2020-05-21
MaastrICCht: Serial measurements in COVID-19-induced acute respiratory disease to unravel heterogeneity of the disease course: design of the Maastricht Intensive Care COVID cohort Coronavirus disease 19 infection Maastricht University Medical Center Netherlands 2020-03-23 2022-03-23 MaastrICCht, NL8613 Phase Not Applicable Recruiting 1 24 Months 250 Bas van Bussel 2020-05-21
BARICIVID-19: Baricitinib Compared to Standard Therapy in Patients With COVID-19 Coronavirus disease 19 infection, Viral pneumonia standard therapy alone, Variable regimens including baricitinib , chloroquine , darunavir + ritonavir , idrossichloroquine , lopinavir + ritonavir , low-molecular weight heparin HIV protease inhibitor, Jak1 tyrosine kinase inhibitor, Jak2 tyrosine kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Azienda Ospedaliero, Universitaria Pisana Italy 2020-05-20 2020-07-30 BARICIVID-19, BARICIVID-19, NCT04393051 Phase 2a Clinical Not yet recruiting 1 2 Months 126 Francesco Menichetti, Francesco Menichetti, MD, Giusy Tiseo, MD, Marco Falcone, Marco Falcone, MD 2020-05-21
Ulinastatin for the Treatment of COVID-19 in Hospitalized Patients Coronavirus disease 19 infection ulinastatin alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Stanford University US 2020-06-30 2020-12-31 56639, NCT04393311 Phase 1/Phase 2 Clinical Not yet recruiting 1 6 Months 150 Kevin V Grimes, MD 2020-05-21
COVID-19 Wellness Survey Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rutgers University US 2020-05-27 2020-05-31 NCT04394104, PRO2020001009 Phase Not Applicable Not yet recruiting 1 1000 Alexandra DelCollo, Alexandra M DelCollo, MS, Sara Elnakib, MPH 2020-05-30
Hydroxychloroquine in COVID-19 Patients Coronavirus disease 19 infection hydroxychloroquine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Zagazig University Saudi Arabia 2020-03-21 2020-08-31 NCT04394442, SNH1352020 Phase 2 Clinical Recruiting 1 5 Months 200 Samah Lutfy, Samah Lutfy, MD, Samah M Lutfy, MD 2020-05-22
Wearable Sensor to Monitor COVID-19 Like Signs and Symptoms Coronavirus disease 19 infection ADAM Sensor alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rehabilitation Institute Of Chicago US 2020-04-20 2022-12-31 NCT04393558, STU00212522 Phase Not Applicable Recruiting 1 32 Months 100 Arun Jayaraman, Arun Jayaraman, PhD, Lori McGee Koch, Lori McGee Koch, PhD 2020-05-22
OnCovid: COVID-19 and Cancer Patients Cancer, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Imperial College London UK 2020-03-24 2022-03-24 282140, NCT04393974, OnCovid Phase Not Applicable Recruiting 1 24 Months 1000 David J Pinato, MD 2020-05-22
Tetrix: The Critical Care Response to the COVID-19 Pandemic in Madrid Coronavirus disease 19 infection Healthy volunteers accepted Hospital Clinico San Carlos Instituto de Investigación Sanitaria del Hospital Clínico San Carlos Spain 2020-04-24 2020-06-30 MADRID COVID TETRIX, NCT04393324, Tetrix Phase Not Applicable Recruiting 1 2 Months 2500 Antonio S Núñez Reiz, Miguel S Sanchez Garcia, MD, Miguel Sanchez Garcia, Miguel Sanchez Garcia, MD. PhD, Miguel Sánchez García, MD 2020-05-29
A clinical study of hydroxychloroquine and azithromycin in the treatment of patients with COVID-19 Coronavirus disease 19 infection azithromycin alone, hydroxychloroquine alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Oxford UK 2020-05-12 Phase Not Applicable Recruiting 1 Chris Butler 2020-05-20
PIA: COVID-19 Pandemic Impact on Alcohol (PIA): A Natural History Study Alcoholism, Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute on Alcohol Abuse and Alcoholism National Institutes of Health Clinical Center US 2020-06-03 2024-12-31 20-AA-N115, 999920115, NCT04391816, PIA Phase Not Applicable Recruiting 1 54 Months 700 Vijay A Ramchandani, Ph.D., Vijay Ramchandani, Ph.D. 2020-05-30
DICER: Dipyridamole to Prevent Coronavirus Exacerbation of Respiratory Status in COVID-19 Blood clotting disorder, Coronavirus disease 19 infection dipyridamole alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Michigan US 2020-05-31 2020-12-31 DICER, HUM00179783, NCT04391179 Phase 2 Clinical Recruiting 1 7 Months 80 Neha Shah, Yogendra Kanthi, MD 2020-05-28
The Use of Peripheral Blood Specimens From Patients Suspected of Having SARS-CoV-2 Infections in Research Studies Intended to Support the Development of COVID-19 Detection Methods, Treatments, and/or Vaccines Coronavirus disease 19 infection COVID-19 testing alone Invivoscribe Technologies Inc US 2020-06-01 2021-06-30 IVS-000-002, NCT04391400 Phase Not Applicable Not yet recruiting 1 13 Months 500 Ellen F Harris, BS, Jason Gerhold, Jordon Thornes 2020-05-20
Hydroxychloroquine and Ivermectin for the Treatment of COVID-19 Infection Coronavirus disease 19 infection, Respiratory tract infection, Viral pneumonia hydroxychloroquine plus ivermectin Chloride channel modulator Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centenario Hospital Miguel Hidalgo Mexico 2020-05-04 2020-09-30 2020-A-09, NCT04391127 Phase 3 Clinical Recruiting 1 4 Months 200 Jose Manuel Arreola Guerra, MD, MSc, PhD, Lucila Martinez, MDPhD, Mario Gonzalez Gamez, MD, Victor Monroy, MD 2020-05-28
ICMR – RUMC COVID 19: Questionnaire based study of drugs taken by healthcare workers to prevent COVID 19 Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Indian Council of Medical Research India 2020-05-18 CTRI/2020/05/025183, ICMR – RUMC COVID 19 Phase Not Applicable Not yet recruiting 15 5000 Dr Bikash Medhi, Dr C D Tripathi, Dr Chetna Desai, Dr Denis Xavier, Dr Dinesh K Badyal, Dr Niyati Trivedi, Dr Pooja Gupta, Dr R Raveendran, Dr S Balakrishnan, Dr Sandeep Kaushal, Dr Sandhya Kamat, Dr Santanu K Tripathi, Dr Sujith Chandy, Dr Suparna Chatterjee, DrHarihar Dikshit 2020-05-21
Global Snapshot of Covid19 patients with kidney dysfunction Coronavirus disease 19 infection, End stage renal disease, Renal injury chronic dialysis alone Hospital Kuala Lumpur Malaysia 2020-05-15 2021-08-11 54867, NMRR-20-911-54867 Phase Not Applicable Not yet recruiting 9 14 Months 200 Dr Ching Chen Hua, Dr EDDIE WONG FOOK SEM, Dr Liu Wen Jiun, Dr Loh Chek Loong, Dr Maisarah Binti Jalalonmuhali, Dr NURUL ZAYNAH BINTI NORDIN, Dr Ruslinda Bt Mustafar, Dr Sunita Bavanandam 2020-05-20
New Antiviral Drugs for Treatment of COVID-19 Coronavirus disease 19 infection Variable regimens including ivermectin , nitazoxanide , ribavirin , zinc Chloride channel modulator Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mansoura University Egypt 2020-05-31 2022-05-31 20.05.69, NCT04392427 Phase 3 Clinical Not yet recruiting 1 24 Months 100 HATEM ELALFY, HATEM ELALFY, MD, TAREK BESHEER, MD 2020-05-19
HCQ for COVID-19 Coronavirus disease 19 infection hydroxychloroquine alone Hospital Kuala Lumpur Malaysia 2020-06-01 2021-06-01 54901, NMRR-20-910-54901 Phase Not Applicable Not yet recruiting 1 12 Months 450 Dr. How Kang Nien 2020-05-20
Evaluation of the effect of trans sodium crocetinate in respiratory distress caused by COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome standard treatment regimen therapy alone, trans sodium crocetinate alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Mashhad University of Medical Sciences Iran 2020-06-21 IR.MUMS.REC.1399.245, IRCT20081019001369N6 Phase 2 Clinical Not yet recruiting 1 30 Amirhoushang Mohammadpour, Hossein Hosseinzadeh, Mohsen Tafaghodi 2020-05-20
HCQ POCKET ECG Ambulatory Telemetry Study Coronavirus disease 19 infection hydroxychloroquine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) All India Institute Of Medical Sciences, Rishikesh, MEDICALgorithmics India 2020-05-26 CTRI/2020/05/025216 Phase Not Applicable Not yet recruiting 1 30 Rohit Walia 2020-05-21
Effectiveness of Siddha medicine, Kabasura kudineer and vitamin c-zinc supplementation in the management of Mild COVID 19 patients Coronavirus disease 19 infection Kabasura Kudineer alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Central Council for Research in Siddha, Government Stanley Medical College Hospital India 2020-05-25 CTRI/2020/05/025215 Phase 1/Phase 2 Clinical Not yet recruiting 1 50 Dr C Anbarasi, Dr S Natarajan 2020-05-21
A multicenter, randomized, double-blind, placebo-controlled trial for Lu-Dang-Shen oral liquid in the treatment of reduced digestion function of convalescent new coronavirus pneumonia (COVID-19) patient Coronavirus disease 19 infection, Indigestion, Viral pneumonia Lu-Dang-Shen alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Wuhan third Hospital China 2020-05-08 2021-05-08 ChiCTR2000032919, ChiMCTR2000003304 Phase 4 Clinical Recruiting 3 12 Months 200 Peng Bo, Qiu tao 2020-05-26
A randomized controlled trial for the efficacy and safety of artemisinin-pipequine tablets in the treatment of the mild and common type novel coronavirus pneumonia (COVID-19) patients whose nCoV Nucleic acid did not turn negative after treated by hydroxychloroquine and Abidor Coronavirus disease 19 infection artemisinin + pipequine alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hongqi hospital of Mudanjing medical university Guangzhou University of Traditional Chinese Medicine China 2020-05-07 2020-12-31 ChiCTR2000032915 Phase 4 Clinical Recruiting 1 7 Months 240 Fengjie Xie, Hongying Zhang 2020-05-21
A clinical trial to study the efficacy of convalescent plasma therapy in COVID-19 patients Coronavirus disease 19 infection convalescent plasma therapy alone Government of India Council of Scientific and Industrial Research (India) India Phase Not Applicable Not yet recruiting 1 Biswanath Sharma Biswas, Shekhar Ranjan Paul, Yogiraj Roy 2020-05-19
Cold Laser Therapy for COVID-19 Positive Patients With Pulmonary Disease Coronavirus disease 19 infection, Lung disease MLS laser alone, regular inpatient medical care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Lowell General Hospital US 2020-04-30 2020-06-30 2020.01, NCT04391712 Phase 2 Clinical Recruiting 1 2 Months 20 Michael McAuliffe, Scott Sigman, MD 2020-05-20
HCW COVID Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sultanah Nur Zahirah Hospital Malaysia 2020-05-28 2020-07-31 54858, NMRR-20-909-54858 Phase Not Applicable Not yet recruiting 1 2 Months 400 nurul ashikin binti adnan 2020-05-21
Traditional Chinese Medicine (TCM); Coronavirus disease 2019 (COVID-19) Coronavirus disease 19 infection, Cough Traditional Chinese Medicine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) National Cancer Institute - Malaysia Malaysia 2020-05-25 2020-08-25 54907, NMRR-20-940-54907 Phase Not Applicable Not yet recruiting 1 3 Months 120 Dr Teo Chiah Shean 2020-05-21
Investigating the Effect of BCG Vaccine on Preventing COVID-19 Infection in Healthcare Staff Exposed to SARS-CoV-2 Coronavirus disease 19 infection BCG vaccine alone, Mantoux Tuberculin alone, tuberculin test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shiraz University of Medical Sciences Iran 2020-06-04 IR.SUMS.REC.1399.181, IRCT20200411047019N1 Phase 3 Clinical Not yet recruiting 4 500 Ali Akbari, Bahman Pourabbas, GHolamreza Pouladfar, Gholamreza Pouladfar, Mohsen Moghadami, Mohsen Moghademi 2020-05-20
Hyperimmune Convalescent Plasma in Moderate and Severe COVID-19 Disease Coronavirus disease 19 infection, Viral pneumonia convalescent hyperimmune plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Federal Medical Biological Agency Russian Federation 2020-05-01 2020-09-15 COVPLAS-COVID19, NCT04392414 Phase 2 Clinical Recruiting 1 4 Months 60 Alexander V Averyanov, MD, PhD, Mikhail A Konoplyannikov, PhD, Vladimir P Baklaushev, MD, PhD 2020-05-20
A clinical trial of BDCA-04 for the treatment of Acute Respiratory Distress Syndrome due to COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome BDCA-04 alone BioCardia Inc Phase not specified Status not specified 0 2020-05-19
NIRS-COV: Effects of Cardiovascular and Pulmonary Optimization on Cerebral Oxygenation in COVID-19 Patients With Severe ARDS Adult respiratory distress syndrome, Coronavirus disease 19 infection, Hypoxia LiDCO alone, near-infrared spectroscopy alone, pulse oxymetry (Massimo) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) HS Hvidovre Hospital Denmark 2020-05-01 2021-05-01 H-20027818, NCT04392089, NIRS-COV Phase Not Applicable Recruiting 1 12 Months 20 Ana-Marija Hristovska, MD, Ana-Marija Hristovska, MD, Ph.d.-student 2020-05-19
Hydroxychloroquine, azithromycin and QT-prolongation Coronavirus disease 19 infection azithromycin plus hydroxychloroquine Taiping Hospital Malaysia 2020-05-19 2020-05-29 55091, NMRR-20-986-55091 Phase Not Applicable Status not specified 1 Dr Hor Chee Peng 2020-05-20
ICPHAM: ICPHAM Coronavirus disease 19 infection Ministry of Health, Malaysia Malaysia 2020-05-25 2021-12-31 54777, ICPHAM, NMRR-20-989-54777 Phase Not Applicable Status not specified 1 19 Months Dr Nur Wahida Binti Zulkifli 2020-05-20
IC-14 (Anti-CD14) Treatment in Patients With SARS-CoV-2 (COVID-19) Coronavirus disease 19 infection, Lung infection, Respiratory disease, Respiratory failure IC-14 alone Monocyte differentiation antigen CD14 inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Implicit Bioscience Ltd University of Washington US 2020-07-31 2021-09-30 COV04, NCT04391309 Phase 2 Clinical Not yet recruiting 1 14 Months 300 Mark Wurfel, MD, PhD 2020-05-26
Colchicine Plus Phenolic Monoterpenes to Treat COVID-19 Coronavirus disease 19 infection, Viral pneumonia standard treatment alone, colchicine plus herbal phenolic monoterpene fractions Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kermanshah University of Medical Sciences Iran 2020-04-01 2020-10-01 1399.062, NCT04392141 Phase 1/Phase 2 Clinical Recruiting 1 6 Months 200 Ahmad Bagheri, MSc, Ali Mostafaie, PhD, Alireza Janbakhsh, MD, Farhad Abdali, BSc, Farid Najafi, MD, PhD, Kavyan Fatahpour, MSc, Mohammad H Zamanian, MD, Siavash Vaziri, MD, Yadollah Shakiba, MD, PhD 2020-05-19
Assessment of boron-containing compounds and Oleoylethanolamide supplementation on the recovery trend in Patients with COVID-19: A double-blind, randomized, placebo-controlled clinical trial Coronavirus disease 19 infection boron containing compound alone, oleoylethanolamide alone, boron containing compound plus oleoylethanolamide Tabriz University of Medical Sciences Iran 2020-05-19 IR.TBZMED.REC.1399.099, IRCT20090609002017N35 Phase 2 Clinical Recruiting 1 40 Alireza Ostadrahimi 2020-05-26
A clinical trial of TargNaturTa, Off-the-Shelf T Cell Therapy for the prevention of COVID-19 Coronavirus disease 19 infection TargNaturTa alone Geneius Biotechnology Ltd Phase Not Applicable Planned 0 2020-05-20
BMI-SARSCoV2: Association Between BMI and COVID-19 Coronavirus disease 19 infection, Obesity Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Regional Universitaire de Lille France 2020-02-01 2020-09-30 BMI-SARSCoV2, DEC20-095, NCT04391738 Phase Not Applicable No longer recruiting 1 8 Months 1200 Francois Pattou, MD 2020-05-21
HYACINTHE: Study Evaluating the Efficacy of Hydroxychloroquine and Azithromycin in Patients With COVID-19 and Hematological Malignancies Coronavirus disease 19 infection, Hematological neoplasm azithromycin plus hydroxychloroquine Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institut de Cancerologie Strasbourg Europe France 2020-05-12 2021-01-31 2020-002002-45, 2020-005, HYACINTHE, NCT04392128 Phase 2 Clinical Not yet recruiting 1 8 Months 114 Anne QUINQUENEL, MD, Bernard DRENOU, MD, Denis CAILLOT, MD, Etienne DAGUINDAU, MD, Luc-Matthieu FORNECKER, MD-PhD, Manon VOEGELIN, Marie Thérèse RUBIO, MD-PhD, Philippe CARASSOU, MD, Stéphanie NGUYEN QUOC, MD-PhD, Valérie SARTORI 2020-05-21
Effect of colchicine in treatment of COVID-19 Coronavirus disease 19 infection colchicine plus hydroxychloroquine Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Shahid Sadoughi University of Medical Sciences and Health Services Iran 2020-04-04 IR.SBMU.NRITLD.REC.1399.018, IRCT20190810044500N5 Phase 3 Clinical Recruiting 1 200 Dr.Fateme Saghafi, Masoud Mirzaei, Nadia Soltani Gerdefaramarzi, Nadia Soltani gerdefaramarzi 2020-05-20
LOGIC: The symptoms, virology and immunity of COVID in healthcare workers Coronavirus disease 19 infection University of Bristol The Grand Appeal UK 2020-03-23 2021-12-31 IRAS 282718, ISRCTN44324934, LOGIC Phase Not Applicable Recruiting 1 21 Months 135 Prof Finn 2020-05-20
Therapeutic plasma exchange (removal of the non-cell portion of blood) in critically ill adult patients with serious SARS CoV-2 disease (COVID-19) Coronavirus disease 19 infection Depuro D2000 Adsorption Cartridge alone, Spectra Optia Apheresis System alone, antibiotics therapy alone, fluid resuscitation alone, mechanical (ARDS-net and prone position) ventilation alone, vasoactive substances therapy alone, hydroxychloroquine plus therapeutic plasma exchange Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) King Saud Medical City Saudi Arabia, United Arab Emirates, Oman 2020-04-01 2020-12-29 ISRCTN21363594, KSMC-IRB-H1R1-29-APR20-01 Phase 2 Clinical Recruiting 4 8 Months Dr Fahad Faqihi, Prof Karakitsos 2020-05-20
RICO: COVID-19 - Study of the Kinetics of the Immune Response During the Intensive Care Unit Stay in Adult Patients Infected With SARS-CoV-2: Multicentric, Non-Interventional Study Coronavirus disease 19 infection, Lung disease Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospices Civils De Lyon ACCRA France 2020-05-11 2021-02-28 2020-A01079-30, 69HCL20_0358, NCT04392401, RICO Phase Not Applicable Recruiting 7 9 Months 200 Anne-Claire LUKASZEWICZ, Pr, Bertrand SOUWEINE, Pr, Carole SCHWEBEL, Pr, Fabienne VENET, Guillaume THIERY, Pr, Hodane YONIS, MD, Laurent ARGAUD, Pr, Marie GROUSSAUD, Thomas RIMMELE, Pr, Vincent PIRIOU, Pr 2020-05-20
Effect of selenium on covid-19 disease Coronavirus disease 19 infection, Respiratory distress syndrome standard protocol treatment alone, hydroxychloroquine plus selenium Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ilam University of Medical Sciences Iran 2020-04-26 IR.MEDILAM.REC.1399.010, IRCT20190418043307N1 Phase 3 Clinical Recruiting 1 100 Ali Nazari, Elham Shafiei 2020-05-20
Evaluating Ehe Effects of Umifenovir (Arbidol) in COVID-19 Coronavirus disease 19 infection Arbidol alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shaheed Beheshti Medical University Iran 2020-04-08 IR.SBMU.RETECH.REC.1399.030, IRCT20151227025726N15 Phase 3 Clinical Recruiting 1 100 Afshin Zarghi, Ali Saffaei, Farzaneh Dastan, Payam Tabarsi 2020-05-20
A clinical study to assess TR-C 19 in the treatment of voluntary COVID-19 patients Coronavirus disease 19 infection TR-C 19 (COVID-19) VSY Biotechnology/Saglik Bilimleri Universitesi alone VSY Biotechnology Phase Not Applicable Not yet recruiting 0 2020-05-20
CTC REGISTRY: Registry of CytoSorb Therapy in COVID-19 ICU Patients Coronavirus disease 19 infection, Respiratory failure Continuous Renal Replacement Therapy (CRRT) alone, CytoSorb device alone, CytoSorb hemoadsorption alone, Extracorporeal Membrane Oxygenation (ECMO) alone, hemoperfusion extracorporeal circuits alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) CytoSorbents Corp 2020-05-31 2021-08-31 2020-001, CTC REGISTRY, FDA EUA, NCT04391920 Phase Not Applicable Not yet recruiting 0 15 Months 1000 Ola Ogunsakin, MD, Peter Nelson, MD 2020-05-20
PROCTOLOCK: Proctologic Practice and Covid-19 Coronavirus disease 19 infection Healthy volunteers accepted Societa Italiana di Chirurgia ColoRettale Katholieke Universiteit Leuven, Queen Mary University of London, The George Institute for Global Health, Universita' Degli Studi "Magna Graecia" Di Catanzaro, University of Pisa Italy 2020-04-15 2020-04-26 1, NCT04392245, PROCTOLOCK Phase Not Applicable Completed 1 1050 2020-05-20
Convalescent Plasma for the Treatment of Severe SARS-CoV-2 (COVID-19) Coronavirus disease 19 infection convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital San Vicente Fundación Clinica de las Americas, Clínica Cardiovid, Clínica Rosario El Tesoro, Clínica Universitaria Bolivariana, Grupo de Inmunodeficiencias primarias Universidad de Antioquia, Hospital Pablo Tobon Uribe Colombia 2020-06-30 2021-12-31 002, NCT04391101 Phase 3 Clinical Not yet recruiting 1 18 Months 231 Fabian A Jaimes Barragan, Epidemiol, Fabian Jaimes, Epidemiologi, Oliver G Perilla Suarez, Hematologist, Oliver Perilla Suarez, Hematologist, Oliver Perilla, Hematologist 2020-05-22
RECOVERY: Resting Energy Expenditure of the Coronavirus (COVID19) Patient in Reanimation Context Coronavirus disease 19 infection, Obesity indirect calorimetry alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Center D 'Arras France 2020-06-01 2020-12-31 2020-04, NCT04391686, RECOVERY Phase Not Applicable Not yet recruiting 1 7 Months 90 Kathleen Jacquez, MSc, vincent Florent, MD, PhD, vincent florent, MD, PhD 2020-05-20
A randomized, placebo-controlled trial to evaluate the effect of two formulations of anti-viral treatment in the reduction of number of COVID-19 patients requiring intensive care treatment Coronavirus disease 19 infection anti-viral treatment alone Senzer Ltd Phase Not Applicable Planned 0 2020-05-19
COVID19-LLC-MW: Observatory of Patients With Chronic Lymphocytic Leukemia / Lymphocytic Lymphoma or Waldenstrom Disease Infected With COVID-19 Chronic lymphocytic leukemia, Coronavirus disease 19 infection, Lymphoplasmacytic lymphoma Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) French Innovative Leukemia Organisation Institut de Cancerologie Strasbourg Europe France 2020-06-01 2022-12-31 COVID19-LLC-MW, FILO-COVID19_LLC-MW, NCT04391946 Phase Not Applicable Not yet recruiting 1 31 Months 50 Luc-Matthieu FORNECKER, Pr, Raoul HERBRECHT, Pr, Valérie ROUILLE 2020-05-19
Efficacy of Extract of of Zingiber Cinnamomum and Zataria multiflora in Covid-19 Disease Coronavirus disease 19 infection Zingiber, Cinnamon zeylanicum and Zataria multiflora extract (Armagan Salamat Zagros Yasuj Company) alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Yasouj University of Medical Sciences and Health Services Iran 2020-05-21 IR.YUMS.REC.1399.029, IRCT20081011001323N25 Phase 2/Phase 3 Clinical Recruiting 1 80 Ali Mousavizadeh, Sadrollah Mehrabi 2020-05-21
A controlled clinical study to assess KB-109 added to supportive self-care (SSC) for outpatients who are positive for SARS-CoV-2 infection with mild-to-moderate COVID-19 Coronavirus disease 19 infection KB-109 alone, supportive self-care (SSC) alone Kaleido Biosciences Inc Phase Not Applicable Planned 0 50 2020-05-19
Evaluating the effect of intravenous N-acetylcysteine versus placebo in the treatment of patients with mild and moderate acute respiratory distress syndrome caused by COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome N-acetylcysteine alone, routine care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hamadan University of Medical Sciences Iran 2020-06-04 IR.UMSHA.REC.1399.153, IRCT20120215009014N355 Phase 2 Clinical Not yet recruiting 1 92 Dr Abbas Taher, Dr. Maryam Mehrpooya, Dr. Saeid Bashirian 2020-05-20
A Study of COVID-19 Convalescent Plasma in High Risk Patients With COVID-19 Infection Coronavirus disease 19 infection convalescent plasma alone Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) TriHealth US 2020-05-05 2020-12-31 20-045, NCT04392232 Phase 2 Clinical Recruiting 2 7 Months 100 Thomas E. Coyle, MD, William Judd, MBA, MHA(C.) 2020-05-21
Oral Manifestation of COVID-19 Patient: A Cross-Sectional Study on Egyptian Population Coronavirus disease 19 infection, Mouth ulcer Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cairo University Egypt 2020-05-30 2020-06-30 54678, NCT04391881 Phase Not Applicable Not yet recruiting 1 1 Month 500 Dina Mounir Elkady, Dina Mounir Elkady, Phd, Rawda Hisham Abdel aziz, Phd 2020-05-20
TMPRSS2: Mechanism of Covid 19 infection in Humans Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Asian Healthcare Foundation India 2020-05-11 COVID19TMPRSS2, CTRI/2020/05/024989, TMPRSS2 Phase Not Applicable Not yet recruiting 1 200 Dr D Nageshwar Reddy, Dr M Sasikala 2020-05-20
COVIDSPERM: Detection of SARS-CoV-2 in Semen of COVID-19 Positive Males Coronavirus disease 19 infection PCR alone Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Universitair Ziekenhuis Brussel Belgium 2020-05-12 2020-08-31 COVIDSPERM, COVIDSPERM, NCT04391829 Phase Not Applicable Not yet recruiting 1 3 Months 20 Michael De Brucker, MD PHD, Valerie Uvin, MD 2020-05-20
The Sungai Buloh Experience: A Retrospective Study in Olfactory and Taste Disturbance in COVID-19 Ageusia, Coronavirus disease 19 infection, Dysgeusia, Dysomia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hospital Sungai Buloh Malaysia 2020-06-01 2020-07-08 54938, NMRR-20-932-54938 Phase Not Applicable Not yet recruiting 2 1 Month Raudha Ezaty binti Ruslan 2020-05-20
Pregnancy with COVID-19 in Malaysia : A Case Series Coronavirus disease 19 infection Female Hospital Sungai Buloh Malaysia 2020-05-13 54904, NMRR-20-931-54904 Phase Not Applicable No longer recruiting 1 Dr Siti Hayati binti Mohd Nahwari 2020-05-20
Homeopathy in prevention of COVID-19 Coronavirus disease 19 infection Arsenicum album alone Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Council for Research in Homoeopathy India 2020-05-13 CTRI/2020/05/024986 Phase Not Applicable Not yet recruiting 1 10000 Dr Anil Khurana, Dr Debadatta Nayak, Dr Raj K Manchanda 2020-05-20
A controlled, multicenter clinical study to assess KB-109 added to supportive self-care (SSC) for outpatients who are positive for SARS-CoV-2 infection with mild-to-moderate COVID-19 Coronavirus disease 19 infection KB-109 alone, supportive self-care (SSC) alone Kaleido Biosciences Inc 2020-05-14 Phase Not Applicable Recruiting 0 350 2020-05-19
APDepCOVID19: Antenatal and postpartum depression among Malaysian women treated as covid-19 and its contributory factors Coronavirus disease 19 infection, Postnatal depression Female Hospital Sungai Buloh Malaysia 2020-05-20 2020-10-19 54717, APDepCOVID19, NMRR-20-917-54717 Phase Not Applicable Not yet recruiting 1 5 Months 77 Dr Norhana Binti Mohd Kasim 2020-05-20
Incidence of COVID-19 Test Conversion in Post-surgical Patients Coronavirus disease 19 infection, Lower respiratory tract infection polymerase chain reaction test alone, serology tests alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Northwell Health Inc US 2020-05-13 2020-07-31 IRB #20-0404, NCT04392323 Phase Not Applicable Recruiting 2 2 Months 500 Aaron Nizam, MD, Andrew W Menzin, MD, MBA, Bruce Farber, MD, Ernesto Molmenti, MD, PhD, MBA, James Crawford, MD, Jose Prince, MD, Matthew Weiss, MD, Michael Nimaroff, MD, MBA, Santiago Miyara, MD 2020-05-20
Validity of at Home Visual Acuity Measurements for Telemedicine During Corona Virus (COVID-19) Pandemic Coronavirus disease 19 infection, Glaucoma, Uveitis non invasive visual acuity testing alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Vanderbilt University Medical Center, US US 2020-05-20 2022-05-01 200826, NCT04391166 Phase Not Applicable Recruiting 1 23 Months 150 Jeffery Kammer, MD, Megan C Barrett, CPO, Saige Wilkins, COA, Sapna Gangaputra, MD, MPH, Sean Donahue, MD, PHD, Shriji Patel, MD, Sylvia Groth, MD 2020-05-29
Efficacy and Safety of Itolizumab in COVID-19 Complications Coronavirus disease 19 infection antibiotics alone, antivirals alone, hydroxychloroquine alone, itolizumab alone, oxygen alone T-cell differentiation antigen CD6 inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Biocon Ltd India 2020-05-01 CTRI/2020/05/024959, ITOLI-C19-02-I-00 Phase 2 Clinical Recruiting 3 30 Dr Milind Nadkar, Dr Murli Mohan, Dr Shashank Joshi, Dr Subramanian Loganathan, Dr Suresh Kumar, Sivakumar Vaidyanathan 2020-05-20
Effect of intrapulmonary injection of processed serum derived from Covid-19 patients in reduction of pulmonary complications Coronavirus disease 19 infection autologous serum alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Tabriz University of Medical Sciences Iran 2019-05-05 IR.TBZMED.REC.1399.014, IRCT20091012002582N21 Phase 2 Clinical No longer recruiting 1 30 Ata Mahmoodpoor, Khosro Adibkia, Leila Roshangar 2020-05-20
IVIG and COVID19 Coronavirus disease 19 infection, Lung injury Flebogamma DIF 5% alone Beta amyloid modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Oroumia University of Medical Sciences Iran 2020-05-09 IR.UMSU.REC.1399.025, IRCT20200501047259N1 Phase 3 Clinical Recruiting 1 40 Naser Gharebaghi, Reza Hajizadeh 2020-05-20
A phase II, open design trial to evaluate KAND-567 in covid-19 patients Coronavirus disease 19 infection KAND-567 alone, best standard treatment alone CX3CR1 chemokine antagonist, Fractalkine ligand inhibitor Kancera AB Capio S:t Görans Hospital, Scandinavian CRO, Scandinavian Development Services AB, Science For Life Laboratory Sweden Phase 2 Clinical Planned 1 40 2020-05-19
Serial, cross-sectional, seroprevalence study of SARS-CoV-2 infection during and after the COVID-19 epidemic in Heidelberg and the Rhein-Neckar region Coronavirus disease 19 infection blood sampling alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Heidelberg SAP SE Germany 2020-05-25 DRKS00021709, S-279/2020 Phase Not Applicable Not yet recruiting 1 1500 Claudia Maria Denkinger 2020-05-20
Intervention Coronavirus disease 19 infection, Respiratory tract infection hyoscyamus niger methanolic extract plus propolis Kashan University of Medical Sciences and Health Services Iran 2020-05-06 IR.KAMUS.REC.1399.001, IRCT20200516047462N1 Phase 2 Clinical Recruiting 1 50 Dr. Hamidreza Banafsheh, Morteza Kosari 2020-05-21
Study to efficacy of Ivermectin in patients of COVID-19 Coronavirus disease 19 infection ivermectin alone, standard of care alone Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) RD Gardi Medical College India 2020-05-24 CTRI/2020/05/025224 Phase 2 Clinical Not yet recruiting 1 50 Dr Ashish Pathak, Dr Sunil Rathi 2020-05-21
COALA: Covid-19 related Obstetric Anesthesia Longitudinal Assessment-Registry Coronavirus disease 19 infection Female University Hospital Wurzburg Germany 2020-03-25 63/20-kr, COALA, DRKS00021772 Phase Not Applicable Recruiting 1 Magdalena Sitter, Peter Kranke 2020-05-20
Efficacy of Tablet AOIM - Z in Prevention of COVID - 19 in High Risk Healthy Police Personnel Coronavirus disease 19 infection AOIM - Z alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Shree Dhootapapeshwar Limited India 2020-06-01 CTRI/2020/05/025222 Phase 4 Clinical Not yet recruiting 1 275 Dr Mahesh Kumar Harit, Dr Vedvati Bhapkar, Dr Vinay Pawar 2020-05-21
SAPRIS-SERO: Health, Perception, Practices, Relations and Social Inequalities in the General Population During the Covid-19 Crisis Coronavirus disease 19 infection dried blood spot sampling alone Healthy volunteers accepted INSERM France 2020-05-01 2020-12-31 2020-A01195-34, C20-26, NCT04392388, SAPRIS-SERO Phase Not Applicable Recruiting 1 8 Months 110000 Fabrice Carrat, Fabrice Carrat, MD 2020-05-20
Create registry of Childhood Cancer patients in India with COVID 19 to provide guidelines for prevention and treatment Cancer, Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Max Super Speciality Hospital India 2020-05-26 CTRI/2020/05/025221, InPOG-EPI-20-02 Phase Not Applicable Not yet recruiting 1 1000 Dr Ramandeep Arora 2020-05-21
Neuropsychiatric effects of COVID-19 Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder Neuropsychiatric effects alone University Malaya Medical Centre Malaysia 2020-05-18 2021-05-18 54785, NMRR-20-905-54785 Phase Not Applicable Not yet recruiting 1 12 Months Dr Tai Mei Ling Sharon 2020-05-20
A study to evaluate anakinra in patients with severe coronavirus disease 2019 (COVID-19) with pneumonia and sHLH Coronavirus disease 19 infection, Hemophagocytic lymphohistiocytosis, Respiratory failure, Viral pneumonia antibiotics alone, anakinra plus hydroxychloroquine Type I IL-1 receptor antagonist Hellenic Institute for the Study of Sepsis Netherlands, Greece Phase 2 Clinical Status not specified 2 8 2020-05-27
COVID-19 Genome Sequence Coronavirus disease 19 infection Genome Sequencing alone The National Institute of Public Health Laboratory, Phnom Penh Malaysia 2020-05-12 2020-12-31 54809, NMRR-20-904-54809 Phase Not Applicable Status not specified 1 7 Months Dr NOORLIZA BINTI MOHAMAD NOORDIN 2020-05-20
PICP19: A clinical trial for validating therapeutic efficacy of convalescent plasma in severe COVID-19 disease Coronavirus disease 19 infection convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Council of Scientific and Industrial Research (India) India 2020-05-20 CTRI/2020/05/025209, PICP19 Phase 2 Clinical Not yet recruiting 1 80 Dipyaman Ganguly, Dr Biswanath Sharma Sarkar, Yogiraj Ray 2020-05-21
Arsenicum album-30c as prophylactic for COVID-19 Coronavirus disease 19 infection arsenicum album-30c alone Healthy volunteers accepted, Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Council for Research in Homoeopathy India 2020-05-24 CTRI/2020/05/025205 Phase 2/Phase 3 Clinical Not yet recruiting 10 33000 Dr Anil Khurana, Dr Ashish Mahajan, Dr Ch Ravender, Dr Debadatta Nayak, Dr KC Murleedharan, Dr Karthikeyan, Dr Lipipushpa Debata, Dr P Hima Bindu, Dr P P Pal, Dr Ramesh Bawaskar, Dr Subhash Kaushik 2020-05-20
Siddha interventions prevention to front line workers Coronavirus disease 19 infection Kabasurakudineer alone, Nilavembukudineer alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Central Council for Research in Siddha India 2020-05-22 CTRI/2020/05/025182 Phase Not Applicable Not yet recruiting 1 366 DrPSathiyarajeswaran 2020-05-22
Evaluation of the Immuno-Stimulatory Potential (Shareera Bala) of an Ayurveda Management Protocol in Cohort of Quarantined Delhi Police under Covid-19 Care Centers- An Exploratory Clinical Study Coronavirus disease 19 infection Anu taila alone, Variable regimens including Herbal tea , Samshamani Vati , aridra khanda Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) All India Institute of Ayurveda India 2020-05-18 CTRI/2020/05/025178 Phase 2 Clinical Not yet recruiting 1 140 Dr VG Huddar, PIprof Dr Tanuja Nesari 2020-05-20
PHOBIC: Mental status of public during lockdown COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Siddha Central Research Institute India 2020-05-22 CTRI/2020/05/025194, PHOBIC Phase Not Applicable Not yet recruiting 1 280 Narrain shree S, Vinoth N P 2020-05-20
PSY: COVID-19: Psychological Impact of COVID-19 Pandemic Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sri Ramachandra Institute of Higher Education and Research United Arab Emirates, US, India 2020-05-19 CTRI/2020/05/025184, PSY: COVID-19 Phase Not Applicable Not yet recruiting 3 1000 Dr Vivian Kapil V 2020-05-20
COVID-19 Long QT: COVID-19 Long QT Coronavirus disease 19 infection azithromycin alone, chloroquine alone, hydroxychloroquine alone, lopinavir + ritonavir alone, smartphone ECG monitoring alone, Variable regimens including azithromycin , chloroquine , hydroxychloroquine , lopinavir + ritonavir HIV protease inhibitor Sarawak Heart Centre Malaysia 2020-05-18 2020-05-19 54921, COVID-19 Long QT, NMRR-20-975-54921 Phase Not Applicable Recruiting 1 30 Dr Koh Keng Tat 2020-05-20
Clinical trial to assess the prognostic repercussions of rosuvastatin treatment in patients discharged after hospitalization for COVID-19 Positive Cardiac failure, Coronavirus disease 19 infection, Deep vein thrombosis, Lung embolism, Myocardial infarction rosuvastatin alone HMG CoA reductase inhibitor Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto de Investigación Sanitaria de la Fundacion Jimenez Diaz Jimenez Diaz Foundation Spain 2020-05-14 2020-001319-26, FJD-COVID-ESTATINAS Phase 3 Clinical Recruiting 1 1080 CLINICAL RESEARCH UNIT 2020-05-20
SEN-CoV-Fadj: Efficacy and Safety Evaluation of Treatment Regimens in Adult COVID-19 Patients in Senegal Coronavirus disease 19 infection azithromycin plus hydroxychloroquine Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institut Pasteur de Dakar Centre Hospitalier Universitaire de Fann, Diamniadio Children Hospital, Senegal, Ministry of Health, senegal Senegal 2020-06-01 2021-06-01 2020-002, NCT04390594, SEN-CoV-Fadj Phase 3 Clinical Not yet recruiting 3 12 Months 258 Abdoul Kane, MD, Aissatou Lakhe, MD, Amadou A. Sall, PhD, Fabien Taieb, MD, PhD, Fatou SD Ndiaye, MD, Khardiata D. Mbaye, MD, Louise Fortes, MD, Maguette N. Fall, MD, Moussa Seydi, MD, Oumar Kane, MD, Pape S. Ba, MD 2020-05-28
Postpartum Sexual Function in Pregnant Women With COVID-19 Coronavirus disease 19 infection, Dyspareunia, Female sexual dysfunction Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Istanbul Bakirkoy Maternity and Children Diseases Hospital Turkey 2020-05-14 2020-08-03 MTALMACCAROL, NCT04389489 Phase Not Applicable Not yet recruiting 1 2 Months 140 Merve Aldikactioglu Talmac, Merve Aldikactioglu Talmac, M.D. 2020-05-19
Respiratory Decompensation and Model for the Triage of COVID-19 Patients Coronavirus disease 19 infection, Respiratory disease COViage alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dascena US 2020-03-24 2020-05-30 051420, NCT04390516 Phase Not Applicable No longer recruiting 1 2 Months 197 2020-05-26
Front liner children in Covid-19 Coronavirus disease 19 infection Selayang Hospital Malaysia 2020-05-01 2020-05-15 54970, NMRR-20-908-54970 Phase Not Applicable Completed 1 Dr Tang Swee Ping 2020-05-20
LB-1148 for Pulmonary Dysfunction Associated With COVID-19 Pneumonia Coronavirus disease 19 infection, Lung inflammation, Respiratory disease, Viral pneumonia tranexamic acid (oral, multiple organ failure), InflammaGen/University of California San Diego alone Serine protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Leading BioSciences Inc 2020-06-30 2021-03-31 LBS-COVID19-201, NCT04390217 Phase 2 Clinical Not yet recruiting 0 9 Months 120 Brian K Wenzel, MS, CCRA, Inge K Bear, MS, CCRA, Michael J Dawson, MD 2020-05-18
Post-operative Recovery Index, Patient Expectations and Satisfaction With Prenatal Care Instrument in Pregnant Patients With COVID-19 Coronavirus disease 19 infection optimum postoperative care alone Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Istanbul Bakirkoy Maternity and Children Diseases Hospital Turkey 2020-05-14 2020-08-03 MTALMAC3, NCT04389515 Phase Not Applicable Not yet recruiting 1 2 Months 75 Merve Aldikactioglu Talmac 2020-05-19
TOFACoV-2: Tofacitinib Plus Hydroxychloroquine versus Hydroxychloroquine in Patients With COVID-19 Interstitial Pneumonia Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia hydroxychloroquine plus tofacitinib citrate (oral, inflammation), Pfizer JAK tyrosine kinase inhibitor, Jak1 tyrosine kinase inhibitor, Jak3 tyrosine kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Universita Politecnica delle Marche ASST Cremona, ASST Papa Giovanni XXIII, Azienda Ospedali Riuniti Marche Nord, Azienda Policlinico Umberto I, Fondazione IRCCS Ca' Granda-Ospedale Maggiore Policlinico, Hospital S. Spirit, Regional Hospital, Varese, Italy, Università Magna Grecia Italy 2020-06-30 2020-10-31 2020-002035-30, NCT04390061, TOFACoV-2 Phase 2 Clinical Not yet recruiting 1 4 Months 116 Armando Gabrielli, Armando Gabrielli, MD 2020-05-21
The impact of Program Kesihatan Optimum (Pohon Sihat) on COVID-19 patients during COVID-19 pandemic Coronavirus disease 19 infection Program Kesihatan Optimum alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Putrajaya Hospital Malaysia 2020-05-18 2020-08-31 54998, NMRR-20-941-54998 Phase Not Applicable Not yet recruiting 1 3 Months Dr Thong Kai Shin 2020-05-19
DPCPM: Disease Progression of COVID-19 Patients in Malaysia Coronavirus disease 19 infection Government of Malaysia Malaysia 2020-05-15 2022-04-30 54834, DPCPM, NMRR-20-945-54834 Phase Not Applicable Not yet recruiting 2 23 Months Devi Peramalah, Dr. Noran Naqiah Hairi 2020-05-19
COVID-19 in the Swedish ICU-cohort: Risk Factors of Critical Care Admission and Intensive Care Mortality Coronavirus disease 19 infection, Diabetes mellitus, Hypertension ACE-inhibitors therapy alone, immunosuppressant therapy alone, intensive care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Uppsala University Center for Clinical Research Dalarna Sweden 2020-06-30 2020-06-30 NCT04390074, UTN: U1111-1251-8195 Phase Not Applicable Not yet recruiting 1 10000 Björn Ahlström, MD, Miklos Lipcsey, PhD 2020-05-22
Correlates between knowledge of COVID 19 and practice among patients in Luyang primary health clinic Coronavirus disease 19 infection KLINIK KESIHATAN LUYANG Malaysia 2020-05-15 2020-06-15 54915, NMRR-20-947-54915 Phase Not Applicable Not yet recruiting 1 1 Month Dr Nurul Akmanidar binti Zainuddin, Dr. Lee Wai Khew 2020-05-19
The Impact and Coping Strategy of COVID-19 Among Taiwan Society and Medical and Nursing Institutes Coronavirus disease 19 infection coping protocol plan alone, standardized crisis management alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kaohsiung Kai-Suan Psychiatric Hospital Taiwan 2020-06-01 2023-07-31 KSPH-2020-03, NCT04389476 Phase Not Applicable Not yet recruiting 1 38 Months 2500 Frank Huang-Chih Chou 2020-05-19