Last updated: Jun 03, 2020 - 02:00 BST
| A clinical trial of AAVCOVID for the prevention of COVID-19 infection |
Coronavirus disease 19 infection |
AAVCOVID alone |
COVID19 Spike glycoprotein modulator |
|
Massachusetts Eye Research and Surgery Institution, Massachusetts General Hospital |
AveXis Inc |
|
2020-12-31 |
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-06-02 |
| Randomized, Double-blind Study in Subjects With SARS-Cov-2 (COVID-19) Virus Infection |
Adult respiratory distress syndrome, Coronavirus disease 19 infection, Hypotension, Hypoxia, Sepsis, Septic shock, Viral pneumonia |
Variable regimens including P2Et extract , hydroxychloroquine , lopinavir + ritonavir |
HIV protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Universitario San Ignacio |
Javeriana University |
Colombia |
2020-06-30 |
2021-06-30 |
CS002-COVID19, NCT04410510 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
0 |
12 Months |
100 |
Angel Garcia, MD. MSc. PhD(c), Margarita Manrrique, MD, MSc |
2020-06-02 |
| Psychological Impact of the Corona Virus Pandemic in Individuals With Psychiatric Disorders |
Anxiety disorder, Coronavirus disease 19 infection, Depression, Psychiatric disorder |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Medical University of Graz |
|
Austria |
2020-04-28 |
2021-04-28 |
32-363 EX 19/20, NCT04410835 |
Phase Not Applicable |
Recruiting |
0 |
12 Months |
1000 |
Eva Reininghaus, Asszo.Prof., Eva Reininghaus, Prof., Nina Dalkner, PD Dr. |
2020-06-02 |
| Evaluation of Therapeutic Effects of Melatonin by Inhibition of NLRP3 Inflammasome in COVID-19 Patients |
Coronavirus disease 19 infection |
melatonin alone, usual treatment alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Baqiyatallah University of Medical Sciences |
|
Iran |
2020-05-12 |
2020-09-25 |
IR.BMSU.REC.1399.039, NCT04409522 |
Phase 2 Clinical |
Recruiting |
0 |
4 Months |
55 |
Mohammad Sadegh Bagheri Baghdasht |
2020-06-02 |
| COVID 19 Viral Clearance Among the Infected Healthcare Workers In Assiut University Hospitals |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Assiut University |
|
Egypt |
2020-05-31 |
2021-06-30 |
COVID19 AMONG HCWS, NCT04409574 |
Phase Not Applicable |
Not yet recruiting |
0 |
13 Months |
31 |
Azza Ezzeldin, professor, Mariam Roshdy Elkhayat, Mariam elkhayat, lecturer |
2020-06-02 |
| Pharmacy Education During Covid-19 Outbreak |
Coronavirus disease 19 infection |
|
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Damanhour University |
|
Egypt |
2020-06-30 |
2021-09-30 |
EDUCATIONAL PROCESS & COVID-19, NCT04409951 |
Phase Not Applicable |
Not yet recruiting |
0 |
15 Months |
100 |
Noha El Bassiouny, PhD |
2020-06-02 |
| Prognosis in Pregnant With COVID-19 |
Coronavirus disease 19 infection |
|
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Istanbul Bakirkoy Maternity and Children Diseases Hospital |
|
Turkey |
2020-03-15 |
2020-05-28 |
MTALMACPROGNOSIS, NCT04409249 |
Phase Not Applicable |
Completed |
0 |
2 Months |
150 |
Merve Aldikactioglu Talmac, MD |
2020-06-02 |
| Treatment With CSL-312 in Adults With Coronavirus Disease 2019 (COVID‑19) |
Coronavirus disease 19 infection, Viral pneumonia |
garadacimab alone, standard of care alone |
Factor XIIa antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
CSL Ltd |
|
|
2020-06-30 |
2020-12-31 |
CSL312_COVID-19, NCT04409509 |
Phase 2 Clinical |
Not yet recruiting |
0 |
6 Months |
124 |
Study Director, Trial Registration Coordinator |
2020-06-02 |
| GLYCOVID-19: Glycemia and Cardiac Function in Patients With COVID-19 |
Coronavirus disease 19 infection, Insulin dependent diabetes, Non-insulin dependent diabetes |
echocardiography alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Steno Diabetes Center Odense |
|
Denmark |
2020-04-20 |
2020-11-30 |
GLYCOVID-19, H-20024279, NCT04410718 |
Phase Not Applicable |
Recruiting |
0 |
7 Months |
100 |
Andreas Andersen, Andreas Andersen, MD |
2020-06-02 |
| MOHC: Home Detox in Medication Overuse Headache (MOH) During Covid-19 Emergency |
Coronavirus disease 19 infection, Headache |
bridge therapy alone, mindfulness program alone, Variable regimens including bromazepam , indomethacin , metoclopramide , pantoprazole , prednisone |
Benzodiazepine receptor agonist, H+ K+ ATPase inhibitor |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fondazione IRCCS Istituto Neurologico Carlo Besta |
|
Italy |
2020-06-30 |
2022-07-31 |
MOH, MOHC, NCT04410536 |
Phase 2 Clinical |
Not yet recruiting |
0 |
25 Months |
25 |
Licia Grazzi, MD, Renato Mantegazza, MD |
2020-06-02 |
| Lung Function, Exercise Capacity and Health-Related Quality of Life After Severe COVID-19 |
Coronavirus disease 19 infection, Lower respiratory tract infection, Respiratory distress syndrome, Viral pneumonia |
Cardiopulmonary exercise test alone, Spirometry alone, lung function test alone |
|
|
Federal University of Rio Grande do Sul |
Conselho Nacional de Desenvolvimento Cientifico e Tecnologico - CNPq, Federal University of Health Science of Porto Alegre, Hospital Nossa Senhora da Conceicao, Hospital de Clinicas de Porto Alegre, Instituto de Educação e Pesquisa do Hospital Moinhos de Vento, Universidado de Passo Fundo |
Brazil |
2020-05-15 |
2022-08-02 |
2020-0169, NCT04410107 |
Phase Not Applicable |
Recruiting |
0 |
26 Months |
134 |
Danilo C Berton, Dr, Igor G Benedetto, Dr, Marcelo B Gazzana, Dr, Marcelo F Nogueira, Dr, Mauricio R Leite, Dr, Nathalia Mendes, Dr, Paulo JZ Teixeira, Dr, Renata D Marques, Dr |
2020-06-02 |
| COVID-PACT: Prevention of Arteriovenous Thrombotic Events in Critically-Ill COVID-19 Patients Trial |
Arterial thrombosis, Coronavirus disease 19 infection, Deep vein thrombosis |
Variable regimens including clopidogrel , enoxaparin sodium , heparin |
Low molecular weight heparin, P2Y12 purinoceptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The TIMI Study Group |
|
US |
2020-05-31 |
2021-05-31 |
2020P001404, COVID-PACT, NCT04409834 |
Phase 4 Clinical |
Not yet recruiting |
0 |
12 Months |
750 |
David A Morrow, MD, MPH, Marc S Sabatine, MD, MPH, Vivian Baird-Zars |
2020-06-02 |
| Lung Fibrotic Changes Associated With SARS-CoV-2 Infection |
Coronavirus disease 19 infection, Pulmonary fibrosis, Viral pneumonia |
chest CT alone, forced spirometry alone, plethysmography alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fundacion Incliva |
|
Spain |
2020-05-21 |
2021-07-31 |
INC-CVD-2020-01, NCT04409275 |
Phase Not Applicable |
Recruiting |
0 |
14 Months |
500 |
Jaime Signes-Costa, Jaime Signes-Costa, MD, PhD |
2020-06-02 |
| A study to assess the usefulness of combination of Vitamin D, magnesium and Vitamin B12 in older COVID-19 patients |
Coronavirus disease 19 infection |
intensive care support alone, oxygen therapy alone, Variable regimens including magnesium , vitamin B12 , vitamin D |
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Singapore Health Services Pte Ltd |
|
Singapore |
2020-03-02 |
2020-05-15 |
CIRB 2020/2344, ISRCTN15324611 |
Phase Not Applicable |
Completed |
0 |
2 Months |
40 |
Dr L Ho |
2020-06-02 |
| A Study to assess CT-P27 for effective treatment for COVID-19 |
Coronavirus disease 19 infection |
CT-P27 alone |
Hemagglutinin modulator |
|
Celltrion Healthcare Co Ltd |
|
|
|
|
|
Phase 2b Clinical |
Planned |
0 |
|
|
Ki-Sung Kwon |
2020-06-02 |
| Effects of the COVID-19 Health Emergency on Biopsychosocial Health |
Coronavirus disease 19 infection |
WHOQOL-BREF survey alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of New Mexico |
|
US |
2020-05-07 |
2021-03-31 |
20-266, NCT04409535 |
Phase Not Applicable |
No longer recruiting |
0 |
10 Months |
500 |
Carla Wilhite, DOT |
2020-06-02 |
| COVID-19 PCR Test Results in Asymptomatic Pregnants |
Coronavirus disease 19 infection |
reverse transcription polymerase chain reaction alone |
|
Healthy volunteers accepted, Female |
Istanbul Medipol University Hospital |
|
Turkey |
2020-04-10 |
2020-05-21 |
GPOLAT1, NCT04410939 |
Phase Not Applicable |
Completed |
0 |
1 Month |
179 |
|
2020-06-02 |
| DISCONNECT-1: Dismantling Covid Induced Neutrophil Extracellular Traps |
Coronavirus disease 19 infection, Dyspnea, Respiratory disease |
dornase alfa alone |
Deoxyribonuclease I stimulator, Deoxyribonuclease stimulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Exactis Innovation |
Hamilton Health Sciences Corp, McGill University Health Center, Research Institute of the McGill University Health Centre, Sir Mortimer B Davis Jewish General Hospital |
Canada |
2020-06-30 |
2021-01-31 |
DISCONNECT-1, DISCONNECT-1, NCT04409925 |
Phase 1 Clinical |
Not yet recruiting |
0 |
7 Months |
25 |
Diana Salazar, MSc, MBA, Jonathan Spicer, MD, Rosa Christodoulopoulos, PhD |
2020-06-02 |
| CO-RNPC: Evaluation of Changes in Weight, Sleep, and Other Psycho-behavioral Parameters During Covid-19 Confinement in Subjects Monitored by the RNPC Network |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital, Grenoble |
|
France |
2020-05-08 |
2020-10-08 |
38RC20.150, CO-RNPC, NCT04409197 |
Phase Not Applicable |
Recruiting |
0 |
5 Months |
4000 |
Jean-Louis PEPIN |
2020-06-02 |
| TRASCOV: Evaluation of Additional Treatments for COVID-19: a Randomized Trial in Niger |
Coronavirus disease 19 infection |
Variable regimens including lopinavir + ritonavir , paracetamol , vitamin C |
HIV protease inhibitor |
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Epicentre (MSF) |
Centre for Medical Research and Health (Cermes), Niamey, Ministry of Public Health, Niger, Université Abdou Moumouni |
Niger |
2020-06-01 |
2021-12-31 |
NCT04409483, TRASCOV, TRASCOV |
Phase 3 Clinical |
Not yet recruiting |
0 |
19 Months |
928 |
Eric Adehossi, Rebecca F Grais |
2020-06-02 |
| UroCovid: The Utility of Enhanced Pre and Post-surgical Work-out to Prevent the Spread of COVID-19 in a Large Urology Department |
Coronavirus disease 19 infection |
RT-PCR alone |
|
|
Fundacio Puigvert |
|
Spain |
2020-03-20 |
2020-12-31 |
FUNDACIÓPUIGVERT, NCT04409899, UroCovid |
Phase Not Applicable |
Recruiting |
0 |
9 Months |
300 |
Alberto Breda, MD, Asier Mercadé Sanchez, MD, Carles Alonso Tarres, MD, PhD, Charo Montañes Bermudez, MD, Francesco Sanguedolce, MD, PhD, Joan Palou Redorta, Prof, Josep Balaña Lucena, MD, Maite Lopez Guerrero, MªJosé Martinez Barcina, MD, Patricia Fernandez de la Llama, MD, Patricia Fernandez-Llama, MD, PhD, Raquel Lopez Martinez, Rosalia Santos da Silva, MD, Sergi Sabaté Tenas, MD |
2020-06-02 |
| Pulmonary Optical Coherence Tomography in COVID-19 Patients |
Adult respiratory distress syndrome, Coronavirus disease 19 infection, Inflammatory disease, Lung embolism, Thrombosis, Viral pneumonia |
5 Fr multipurpose catheter (Cordis) alone, 5Fr MP catheter alone, 6 Fr 11 cm sheath alone, Recover catheter (Hexacath) alone, Storq wire (Cordis) alone, angiography alone, contrast CT scan alone, femoral vein echo-guided puncture alone, iodinated contrast administration alone, pulmonary optical coherence tomography alone, selective pulmonary artery cannulation alone, trans-thoracic echocardiography alone, unfractionated heparin alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
IRCCS San Raffaele |
|
Italy |
2020-05-27 |
2020-06-30 |
NCT04410549, OCT COVID |
Phase 2 Clinical |
Recruiting |
0 |
1 Month |
10 |
MARCO BRUNO MARIA ANCONA, SUB INVESTIGATOR, MATTEO MONTORFANO, PRINCIPAL INVESTIGATOR, Marco Bruno Maria Ancona, Sub Investigator, Matteo Montorfano, Matteo Montorfano, PI |
2020-06-02 |
| AMPoL: Antiseptic Mouthwash / Pre-Procedural Rinse on SARS-CoV-2 Load (COVID-19) |
Coronavirus disease 19 infection |
CloSYS mouthwash, Rowpar Pharmaceutical Inc alone, Crest Pro-Health Multi-Protection mouthwash alone, Oral-B Mouth Sore mouthwash alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of California San Francisco |
|
US |
2020-07-01 |
2021-08-31 |
20-30874, AMPoL, NCT04409873, R00RG2901 |
Phase 2 Clinical |
Not yet recruiting |
0 |
14 Months |
120 |
Sepideh Banava, DDS, MPH, Stuart A Gansky, DrPH |
2020-06-02 |
| TRACK-COVID: Investigation of COVID-19 symptoms and potential immunity in the general population |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted |
University of Cambridge |
Health Data Research UK, National Institute for Health Research (NIHR) |
UK |
2020-03-27 |
2021-06-06 |
2, IRAS 283239, ISRCTN55886926, TRACK-COVID |
Phase Not Applicable |
Not yet recruiting |
0 |
14 Months |
90000 |
Dr Amy McMahon, Prof DiAngelantonio |
2020-06-02 |
| HBOT: Hyperbaric Oxygen Therapy in Non-ventilated COVID-19 Patients |
Coronavirus disease 19 infection, Respiratory insufficiency |
antibiotic therapy alone, bronchodilator therapy alone, hyperbaric oxygen chamber (RestorixHealth) alone, hyperbaric oxygen therapy alone, oxygen alone, standard treatment alone, steroid therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Maimonides Medical Center |
|
US |
2020-06-01 |
2021-03-30 |
120-20-ASF, HBOT, NCT04409886 |
Phase 2 Clinical |
Not yet recruiting |
0 |
9 Months |
30 |
Gene Sobol, Ory Weisel, Ory Weisel, MD |
2020-06-02 |
| ATTAC-19: Aggrenox To Treat Acute Covid-19 |
Coronavirus disease 19 infection, Hypoxia |
dipyridamole + acetylsalicylic acid (stroke), Boehringer alone, standard of care alone |
Cyclooxygenase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Rutgers University |
Boehringer Ingelheim International GmbH |
US |
2020-06-21 |
2021-12-15 |
ATTAC-19, NCT04410328, PRO2020001399 |
Phase 3 Clinical |
Not yet recruiting |
0 |
17 Months |
132 |
Amit Singla, MD, Olga Kovalenko, D, PhD, CCRC |
2020-06-02 |
| H4H-01: The effect of Alfalife in reducing low-grade inflammation |
Coronavirus disease 19 infection, Diabetes mellitus, Inflammatory disease, Weight gain |
Alfalife alone, balanced hypolipidemic and isocaloric diet intake alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Digitcal Srl |
Freia Farmaceutici Srl |
Italy |
2020-01-15 |
2020-10-31 |
H4H-01, H4H-01, ISRCTN12319920 |
Phase Not Applicable |
Not yet recruiting |
0 |
9 Months |
24 |
Dr Lina Giuseppina Gentile, Dr Maurizio Cipolla, Prof Antonio V. Gaddi, Prof Francesco Visioli |
2020-06-02 |
| COVIDHomeless: Morbi-mortality by COVID-19 Among Homeless People in Marseille: a Cohort Study |
Coronavirus disease 19 infection |
serological test alone, virological test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assistance Publique Hopitaux De Marseille |
|
France |
2020-05-28 |
2021-01-27 |
2020-32, 2020-A01398-31, COVIDHomeless, NCT04408131 |
Phase Not Applicable |
Recruiting |
0 |
8 Months |
2000 |
Aurelie TINLAND, PH, Jean-Olivier ARNAUD, Director |
2020-06-01 |
| COVID-19 HD: High Versus Low LMWH Dosages in Hospitalized Patients With Severe COVID-19 Pneumonia and Coagulopathy |
Coronavirus disease 19 infection, Thromboembolism, Viral pneumonia |
enoxaparin sodium biosimilar, Techdow alone |
Low molecular weight heparin |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital, Modena |
|
Italy |
2020-06-30 |
2021-06-30 |
2020-001972-13, COVID-19 HD, NCT04408235 |
Phase 3 Clinical |
Not yet recruiting |
0 |
12 Months |
300 |
Marco Marietta, MD, Pasquale Mighali |
2020-06-01 |
| GLS-1200 Topical Nasal Spray to Prevent SARS-CoV-2 Infection (COVID-19) in Health Care Personnel |
Coronavirus disease 19 infection |
GLS-1200 alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
GeneOne Life Science Inc |
|
US |
2020-05-31 |
2020-11-30 |
NCT04408183, T2R-002 |
Phase 2 Clinical |
Not yet recruiting |
0 |
6 Months |
225 |
Medical Monitor, Project Manager, Rupa Chowdary |
2020-06-01 |
| PISCOV: A Clinical trial to study the efficacy of pH based Integrated SARS Cov-2 Immunity in Human Subjects |
Coronavirus disease 19 infection |
sunlight exposure alone, Variable regimens including Arsenic album , Chlorpromazine , High pH diet , NBE extract concoction , Tea(Theoxanthine ) |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Siddhartha Hospital |
|
India |
2020-06-07 |
|
CTRI/2020/05/025490, PISCOV, U1111-1252-7438 |
Phase 2/Phase 3 Clinical |
Status not specified |
0 |
|
110 |
Mr Javed Khan, Sapna Agarwal, Siddharth Agarwal |
2020-06-02 |
| The effect of interferon on the treatment of covid19 patients |
Coronavirus disease 19 infection |
interferon treatment alone, treatment protocol from the Ministry of Health alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Ghoum University of Medical Sciences |
|
Iran |
2020-03-20 |
|
IR.MUQ.REC.1399.089, IRCT20160118026097N3 |
Phase 3 Clinical |
Recruiting |
0 |
|
60 |
hasan adeli, jamshid vfaeemanesh |
2020-06-02 |
| Efficacy and Safety of Ivermectin and Doxycycline in Combination or IVE Alone in Patients With COVID-19 Infection |
Coronavirus disease 19 infection |
ivermectin alone, standard care alone, doxycycline hyclate plus ivermectin |
Chloride channel modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
International Centre For Diarrhoeal Disease Research, Bangladesh |
|
Bangladesh |
2020-06-30 |
2020-07-31 |
NCT04407130, PR-20039 |
Phase 2 Clinical |
Not yet recruiting |
0 |
1 Month |
72 |
Wasif Ali Khan, MBBS, MHS, Wasif Ali Khan, MBBS,MHS |
2020-06-02 |
| The efficacy of Homeopathic medicines in the prevention of COVID-19 in Quarantined or Exposed Individuals |
Coronavirus disease 19 infection |
Variable regimens including Arsenic Album , Bryonia alba , Camphora , Coronavirus related nosodes |
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Life Force Foundation Trust |
|
India |
2020-06-08 |
|
CTRI/2020/05/025491 |
Phase 2 Clinical |
Not yet recruiting |
0 |
|
1000 |
Dr Rajesh Shah |
2020-06-02 |
| Epidemiology of Acute Kidney Injury in COVID19 Disease in United Kingdom |
Coronavirus disease 19 infection, Renal injury |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospitals Of Derby and Burton NHS Foundation Trust |
|
UK |
2020-06-01 |
2021-05-21 |
NCT04407156, UHDB/2020/050 |
Phase Not Applicable |
Not yet recruiting |
0 |
11 Months |
350 |
Nitin V Kolhe, MD |
2020-06-02 |
| Covid-Simile study: Homeopathy for Covid-19 in primary care |
Coronavirus disease 19 infection |
Natrum muriaticum LM2 alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fundação Universidade Federal De São Carlos, HN-Cristiano Homeopatia |
|
South America, Brazil |
2020-06-15 |
2020-12-20 |
Covid-Simile study, UMIN000040602 |
Phase 2 Clinical |
Not yet recruiting |
0 |
6 Months |
100 |
Ubiratan Adler |
2020-06-01 |
| A clinical trial of ORP-100S for the treatment of COVID-19 infection |
Coronavirus disease 19 infection |
ORP-100 alone |
Thioredoxin stimulator |
|
OrPro Therapeutics Inc |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-06-01 |
| Asymptomatic COVID-19 |
Coronavirus disease 19 infection |
|
|
|
Hospital Tengku Ampuan Afzan |
|
Malaysia |
2020-05-27 |
2020-06-27 |
55001, NMRR-20-1050-55001 |
Phase Not Applicable |
Status not specified |
1 |
1 Month |
100 |
Dr WONG YEN SHEN |
2020-06-01 |
| postICU-COVID19: postICU-COVID19 |
Coronavirus disease 19 infection, Psychiatric disorder |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Kuala Lumpur |
|
Malaysia |
2020-05-26 |
2020-08-31 |
54967, NMRR-20-1049-54967, postICU-COVID19 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
10 |
Dr Lim Hong Tak |
2020-06-01 |
| Clinical clues and management of suspected COVID-19 |
Coronavirus disease 19 infection |
|
|
|
Tuanku Jaafar Hospital |
|
Malaysia |
2020-05-24 |
2020-05-27 |
55109, NMRR-20-1045-55109 |
Phase Not Applicable |
Completed |
1 |
|
500 |
Dr. Poh Kok Wei |
2020-06-01 |
| COVID-19 Selangor: COVID-19 Selangor |
Coronavirus disease 19 infection |
|
|
|
JABATAN KESIHATAN NEGERI SELANGOR |
|
Malaysia |
2020-06-01 |
2020-06-30 |
54912, C19Sel2020 v1.1, COVID-19 Selangor, NMRR-20-1043-54912 |
Phase Not Applicable |
Status not specified |
2 |
1 Month |
|
Dr Anita Suleiman |
2020-06-01 |
| ILIAD-7-FR: Interleukin-7 to Improve Clinical Outcomes in Lymphopenic patients With COVID-19 Infection FR BL Cohort |
Coronavirus disease 19 infection, Lymphocytopenia, Respiratory failure |
CYT-107 alone |
IL-7 receptor agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
RevImmune SAS France |
Amarex Clinical Research, University Hospital, Limoges |
France |
2020-06-01 |
2020-12-30 |
CLI107 COVID FR (ILIAD-7-FR), ILIAD-7-FR, NCT04407689 |
Phase 2 Clinical |
Not yet recruiting |
0 |
6 Months |
48 |
Bruno François, MD, Frederique Berbille, MHSc, Michel Morre, DVM MSc |
2020-06-01 |
| COVID-19: IMPROVISE: COVID-19: IMPROVISE |
Coronavirus disease 19 infection |
|
|
|
National Institutes of Health Malaysia |
|
Malaysia |
2020-05-29 |
2020-07-31 |
54936, COVID-19: IMPROVISE, NMRR-20-1040-54936 |
Phase Not Applicable |
Not yet recruiting |
1 |
2 Months |
|
Mr. HING YEE LIANG |
2020-06-01 |
| VIVI: Vienna Versus SARS-CoV-2 Virus Study |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted |
Medical University of Vienna |
|
Austria |
2020-05-27 |
2021-06-27 |
EK 1387/2020, NCT04407429, VIVI |
Phase Not Applicable |
Recruiting |
2 |
13 Months |
12000 |
Christian Hengstenberg, Univ.-Prof., Christian Nitsche, Dr., Christoph Binder, Prof., Daniela Gompelmann, Prof., Eva Schernhammer, Prof., Marco Idzko, Prof., Martin Riesenhuber, Dr., Rainer Oberbauer, Prof., Tanja Stamm, Prof., Thomas A Zelniker, DDr., Thomas Perkmann, Dr. |
2020-06-01 |
| PEP-Q: Efficacy of Hydroxychloroquine (HCQ) as Post Exposure Prophylaxis (PEP) for Prevention of COVID-19 |
Coronavirus disease 19 infection |
home quarantine alone, hydroxychloroquine alone, personal hygiene alone, post exposure prophylaxis alone, social distancing alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Postgraduate Institute of Medical Education and Research |
|
India |
2020-03-01 |
2020-06-30 |
IEC-04/2020-1624, NCT04408456, PEP-Q |
Phase 3 Clinical |
Recruiting |
0 |
4 Months |
200 |
Deba P Dhibar, MD |
2020-06-01 |
| Outpatient Clinic in Obesity Care During COVID-19 Outbreak: Physically Far, Virtually Near |
Coronavirus disease 19 infection, Obesity |
Medical counselling alone, Telemedicine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Campania Luigi Vanvitelli |
|
Italy |
2020-03-03 |
2020-05-04 |
NCT04407663, TELEMEDICINE |
Phase Not Applicable |
Completed |
0 |
2 Months |
138 |
Claudio Gambardella, Researcher |
2020-06-01 |
| Clinical trial study of the therapeutic effect of ivermectin, besides Kaletra and chloroquine in patients with Coronavirus disease 2019 (COVID-19) |
Coronavirus disease 19 infection |
Variable regimens including chloroquine , ivermectin , lopinavir + ritonavir |
Chloride channel modulator, HIV protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ahvaz University of Medical Sciences |
|
Iran |
2020-05-30 |
|
IR.AJUMS.REC.1399.194, IRCT20200422047168N2 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
|
60 |
Ahvaz University of Medical Sciences, Ali akbar Shayesteh, Zahra Shokati |
2020-06-01 |
| Stem cell therapy in Covid-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
allogenic mesenchymal stem cell-derived umbilical cord transplantation alone, other common treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Mashhad University of Medical Sciences |
|
Iran |
2020-06-14 |
|
IR.MUMS.REC.1399.150, IRCT20160809029275N1 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
20 |
Dr.Mahnaz Amini, Seyad Jalil Tavakol Afshari |
2020-06-01 |
| APRONOX: Awake Prone Positioning and Oxygen Therapy in Patients With COVID-19 |
Coronavirus disease 19 infection |
awake prone positioning alone, oxygen therapy alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital General San Juan del Rio |
|
Mexico |
2020-05-01 |
2020-07-30 |
1178/SESEQ-HSGJR/08-05-20/UTI, APRONOX, NCT04407468 |
Phase Not Applicable |
Recruiting |
6 |
2 Months |
368 |
Cesar Alonso Bello, MD, Cesar Alonso Bello, MD, MSc, Ernesto Deloya Tomas, MD, Ernesto Deloya Tomas, MD, MSc, Gabiel Cruz Sanchez, MD, Gabriel Cruz Sanchez, MD, Karen P Pozo Cortes, MD, Luis Macias Garcia, MD, Luis Macias, Garcia, Orlando Perez Nieto, MD, Orlando R Perez Nieto, MD |
2020-06-01 |
| Effects of licorice in treatment of COVID-19 |
Coronavirus disease 19 infection |
hydroxychloroquine sulfate plus licorice |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Bandare-abbas University of Medical Sciences |
|
Iran |
2020-05-21 |
|
IR.HUMS.REC.1399.066, IRCT20200506047323N2 |
Phase 3 Clinical |
Recruiting |
1 |
|
60 |
Mohammad Fathalipour, Parivash Davoodian |
2020-06-01 |
| PS-COVID: Peer support training for adolescents during the COVID-19 outbreak |
Coronavirus disease 19 infection |
Peer Support Training alone |
|
Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
University of Oxford |
|
UK |
2020-04-01 |
2020-07-10 |
ISRCTN99248812, PS-COVID, R69810/RE001 |
Phase Not Applicable |
Recruiting |
2 |
3 Months |
100 |
Dr Pavarini |
2020-06-01 |
| A phase II clinical trial of SARS-CoV-2 live-attenuated vaccine for the prevention of COVID-19 infection |
Coronavirus disease 19 infection |
COVID-19 vaccine (measles vaccine vector technology), Institut Pasteur/Themis Bioscience/University of Pittsburgh alone |
|
|
Themis Bioscience GmbH |
|
|
|
|
|
Phase 2 Clinical |
Planned |
0 |
|
|
|
2020-06-01 |
| FALCON-C19: Facilitating AcceLerated Clinical Validation Of Novel Diagnostics for COVID-19 |
Coronavirus disease 19 infection |
blood sampling alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Manchester University NHS Foundation Trust |
|
|
2020-06-01 |
2021-05-31 |
B00944, FALCON-C19, NCT04408170 |
Phase Not Applicable |
Not yet recruiting |
0 |
12 Months |
1000 |
Eloïse Cook, Richard Body |
2020-06-01 |
| Testing the Accuracy of a Digital Test to Diagnose Covid-19 |
Coronavirus disease 19 infection |
Covid Symptom Study app, Zoe Global Ltd alone, Covid-19 swab PCR test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
King's College London |
Department of Health, ZOE Global Ltd |
Sweden, US, UK |
2020-05-28 |
2021-05-10 |
COVID-19 VALIDATION STUDY, NCT04407585 |
Phase Not Applicable |
Not yet recruiting |
4 |
11 Months |
1000000 |
Andrew Chan, Claire Steves, Inbar Linenberg, MSc, Peter Sasieni, Sarah Berry, Sebastien Ourselin, Tim Spector |
2020-06-01 |
| A phase I clinical trial of COVID-19 vaccine for the treatment of Coronavirus disease 19 infection |
Coronavirus disease 19 infection |
SARS-CoV-2 vaccine (COVID-19), Zolovax alone |
Endoplasmin modulator |
|
Heat Biologics Inc |
Waisman Clinical Biomanufacturing Facility |
|
|
|
|
Phase 1 Clinical |
Planned |
0 |
|
|
|
2020-06-01 |
| The effect of Stopcivir syrup in patients with COVID-19 |
Coronavirus disease 19 infection |
Stopcivir alone, standard treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Mazandaran University of Medical Sciences |
|
Iran |
2020-04-05 |
2020-06-06 |
IR.MAZUMS.REC.1399.061, IRCT20200411047016N1 |
Phase 3 Clinical |
Recruiting |
1 |
2 Months |
150 |
Majid Saeedi, Motahareh Rouhi Ardeshiri, Seyde Sedighe Yousefi |
2020-06-02 |
| The analysis of COVID-19 on gastrointestinal endoscopy |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Yokohama City University |
|
Japan |
2020-06-01 |
|
UMIN000040587 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
500 |
Takuma HIGURASHI |
2020-06-02 |
| COVID-SERA: COVID-Serology in Rheumatoid Arthritis (COVID-19) |
Coronavirus disease 19 infection, Rheumatoid arthritis |
2019-nCoV IgM/IgG Diagnostic Test Kit alone, COVID-19 IgG/IgM Rapid Test Kit alone, IgM/IgG Rapid Qualitative Test Kit alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital, Montpellier |
|
France |
2020-05-01 |
2020-09-30 |
COVID-SERA, NCT04407559, RECHMPL20-0330 |
Phase Not Applicable |
No longer recruiting |
1 |
5 Months |
216 |
Rosanna FERREIRA, MD |
2020-06-02 |
| GPC: The effect of Guduchi (Tinospora cordifolia) as a prophylactic measure among high risk population (Health Care Workers/Containment Zone Population) exposed to COVID-19 |
Coronavirus disease 19 infection |
Guduchi capsule alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Central Council for Research in Ayurvedic Sciences |
|
India |
2020-06-29 |
|
CTRI/2020/05/025485, GPC |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
5000 |
Dr P V V Prasad |
2020-06-02 |
| Efficacy and safety of leflunomide for Refractory novel coronavirus pneumonia (COVID-19): An Open-label Controlled Study |
Coronavirus disease 19 infection, Viral pneumonia |
Standard treatment alone, leflunomide alone |
Dihydroorotate dehydrogenase inhibitor, Protein tyrosine kinase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Qilu Hospital of Shandong University |
|
China |
2020-03-12 |
2020-05-17 |
ChiCTR2000033372 |
Phase 0 Clinical |
Completed |
1 |
2 Months |
30 |
Hu Zhao |
2020-06-02 |
| A small clinical trial to study the effects of stem cell therapy on hospitalized COVID-19 patients |
Coronavirus disease 19 infection |
stem cell therapy alone |
|
|
Personalized Stem Cells Inc |
|
US |
|
|
|
Phase Not Applicable |
Planned |
1 |
|
|
|
2020-06-01 |
| IMMUNO-COVID: Study of Kinetics and Efficacy of the Immune Response Against COVID-19 Among Hospital Staff |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Direction Centrale du Service de Sante des Armees |
|
France |
2020-06-02 |
2021-06-02 |
2020-COVID19-04, IMMUNO-COVID, NCT04408001 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
800 |
Damien RICARD, MD, PhD, Jean-Nicolas TOURNIER, MD, PhD |
2020-06-02 |
| Development of Smell based test for identifying COVID-19 infection |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Agri Food Biotechnology Institute |
|
India |
2020-06-04 |
|
CTRI/2020/05/025487 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
300 |
Dr Mahendra Bishnoi, Sanjay Kumar Bhadada |
2020-06-01 |
| COPD in the Time of COVID-19 |
Chronic obstructive pulmonary disease, Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Leicester |
University Hospitals of Leicester - Leicester Royal Infirmary |
UK |
2020-05-31 |
2021-06-30 |
0778, NCT04407598 |
Phase Not Applicable |
Not yet recruiting |
1 |
13 Months |
350 |
Hamish J C McAULEY, MBBS, Hamish J C McAuley, MBBS, Neil J Greening, PhD, Omer Elneima, MBBS |
2020-06-01 |
| Convalescent Plasma Therapy in Patients With COVID-19 |
Coronavirus disease 19 infection |
Convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Bio Farma |
Eijkman Institute for Molecular Biology, Gatot Soebroto Army Center Hospital |
Indonesia |
2020-05-01 |
2020-08-01 |
3471041S322342020040800002, NCT04407208 |
Phase 1 Clinical |
Recruiting |
2 |
3 Months |
10 |
Familia Bela, Sp.PA, Marliana Sri Rejeki, Sp.FK, Nana Sarnadi, Sp.OG, dr. Marliana Sri Rejeki, Sp.FK |
2020-06-02 |
| GGVC19: Clinical study on Guduchi Ghana Vati as a preventive remedy in pandemic of COVID-19 |
Coronavirus disease 19 infection |
Guduchi Ghana Vati alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
National Institute of Ayurveda Jaipur Rajasthan |
|
India |
2020-06-03 |
|
CTRI/2020/05/025488, GGVC19, NIA-CVD-19/2020/01 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
12000 |
Dr PawanKumar Godatwar, Prof Dr Sanjeev Sharma |
2020-06-02 |
| Clinical Study of AT-301(nasal spray,Atossa Genetics Inc) for the treatment of COVID-19 |
Coronavirus disease 19 infection |
AT-301(nasal spray,Atossa Genetics Inc) alone |
|
|
Atossa Genetics Inc |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-06-01 |
| The Use of Oxygen Hoods as Compared to Conventional High-flow Oxygen Delivery Systems, the Effects on Oxygenation, Intubation and Mortality Rates in Hypoxic Patients With COVID-19 |
Coronavirus disease 19 infection, Hypoxia |
oxygen hood alone |
|
|
Northwell Health Inc |
|
US |
2020-03-06 |
2020-05-01 |
HOODSTUDY701, NCT04407260 |
Phase Not Applicable |
Completed |
1 |
1 Month |
136 |
David Dayya, David Dayya, DO, PhD, MPH, Owen J O'Neill, MD, MPH, FUHM |
2020-06-02 |
| Evaluation of the Relationship Between Zinc, Vitamin D and B12 Levels in the COVID-19 Positive Pregnant Women |
Coronavirus disease 19 infection, Hypozincemia, Vitamin D deficiency |
|
|
Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Istanbul Bakirkoy Maternity and Children Diseases Hospital |
Ibrahim Polat Holding Inc |
Turkey |
2020-04-20 |
2020-06-03 |
NCT04407572, ZINC-DVIT-COVID19 |
Phase Not Applicable |
No longer recruiting |
1 |
1 Month |
45 |
Pınar Yalcin bahat |
2020-06-02 |
| Plasmapheresis and plasma exchanges; usefulness in covid-19 critically ill patients |
Coronavirus disease 19 infection |
plasma exchange alone, plasmapheresis alone |
|
Children (6-12 yrs), Adolescents (13-17 yrs) |
Shaheed Beheshti Medical University |
|
Iran |
2020-03-20 |
|
IR.SBMU.NRITLD.REC.1399.016, IRCT20150107020592N23 |
Phase 2 Clinical |
Recruiting |
0 |
|
15 |
Dr Seyyed Mohamadreza Hashemian, Seyed Mohammad Reza Hashemian |
2020-06-02 |
| SILVERBULLET: Efficacy, Safety and Tolerability of Ivermectin in Subjects Infected With SARS-CoV-2 With or Without Symptoms |
Coronavirus disease 19 infection |
ivermectin plus paracetamol |
Chloride channel modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Biomedical Research for the Development of Farmacos S.A. from C.V |
|
Mexico |
2020-06-30 |
2020-10-31 |
NCT04407507, SARS-COV-IVERMX-01, SILVERBULLET |
Phase 2 Clinical |
Not yet recruiting |
1 |
4 Months |
66 |
Alma M Perez, MD, Carmen de la Rocha, PhD, Marco A Cid |
2020-06-02 |
| A proof-of-concept clinical, randomized, multicenter, double-blind, placebo-controlled trial to assess the safety and efficacy of CERC-002 in patients with COVID-19 cytokine storm induced Acute Respiratory Distress Syndrome (ARDS) |
Coronavirus disease 19 infection, Respiratory distress syndrome |
CERC-002 alone |
Tumor necrosis factor 14 ligand inhibitor |
|
Cerecor Inc |
|
|
2020-06-30 |
|
|
Phase 2 Clinical |
Not yet recruiting |
0 |
|
82 |
|
2020-06-01 |
| COVIDiet: Dietary Intake and Eating Habits During the COVID-19 Pandemic |
Coronavirus disease 19 infection |
Keenoa app alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
McGill University |
|
Canada |
2020-05-25 |
2022-08-31 |
20-04-064, COVIDiet, NCT04407533 |
Phase Not Applicable |
Recruiting |
1 |
27 Months |
1920 |
Stéphanie Chevalier, Stéphanie Chevalier, PhD |
2020-06-01 |
| The Relationship Of D-Dimer With Severity And Mortality In SARS-COV-2 Patients |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Faculty of Medicine Airlangga University |
|
Asia |
2020-05-10 |
|
UMIN000040433 |
Phase Not Applicable |
Completed |
0 |
|
|
Johanes Nugroho |
2020-06-02 |
| CAPTURE: COVID-19: A POC Test Under Research and Evaluation |
Coronavirus disease 19 infection |
LumiraDx device alone, LumiraDx platform SARS-CoV-2 assay alone, fingerstick capillary sampling alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Lumiradx UK Ltd |
|
UK |
2020-04-30 |
2022-04-30 |
CAPTURE, NCT04408066, S-CLIN-PROT-00028 |
Phase Not Applicable |
Recruiting |
3 |
24 Months |
2000 |
Ben Bloom, Dave Chadwick, Jayne Ellis, Samer Elkhodair, William Niven |
2020-06-02 |
| Endothelial Function, Inflammation and Organ Dysfunction in COVID-19 |
Coronavirus disease 19 infection, Inflammatory disease |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Guy's & St Thomas' Hospital NHS Trust |
Kings College Hospital NHS Trust |
UK |
2020-06-01 |
2021-05-31 |
282930, NCT04408365 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
82 |
Marlies Ostermann, MD, PhD, Nuttha Lumlertgul, MD, PhD |
2020-06-02 |
| ACES: Efficacy and Safety of Angiotensin II Use in COVID-19 Patients With Acute Respiratory Distress Syndrome |
Coronavirus disease 19 infection, Respiratory distress syndrome |
anakinra alone, angiotensin II alone |
Angiotensin II receptor agonist, Type I IL-1 receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Guy's & St Thomas' Hospital NHS Trust |
Australian and New Zealand Intensive Care Research Centre, Monash University, Royal Surrey County Hospital NHS Trust |
UK |
2020-06-01 |
2021-05-01 |
283005, ACES, NCT04408326 |
Phase Not Applicable |
Not yet recruiting |
1 |
11 Months |
50 |
Marlies Ostermann, Marlies Ostermann, MD, PhD, Nuttha Lumlertgul, MD, PhD |
2020-06-02 |
| Vitamin D Testing and Treatment for COVID 19 |
Coronavirus disease 19 infection |
vitamin D3 alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Arizona State University |
Southwest College of Naturopathic Medicine |
US |
2020-05-19 |
2021-05-18 |
NCT04407286, STUDY00011960 |
Phase 1 Clinical |
Recruiting |
0 |
12 Months |
100 |
James B Adams, PhD, James B. Adams, PhD, Jasmine Kirby, BS, Sarah Trahan, NMD |
2020-06-01 |
| CORONA: COVID-19 Research in Organ Transplant Recipients |
Coronavirus disease 19 infection |
immunosuppressive treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Vastra Gotaland Region |
|
Sweden |
2020-06-01 |
2024-05-01 |
CORONA, COV-19-SU-TX, NCT04407221 |
Phase Not Applicable |
Not yet recruiting |
0 |
47 Months |
1100 |
John M Softeland, MD, PhD, John Mackay Softeland, MD, PhD, Mihai Oltean, MD, PhD, Vanda Friman, MD, PhD |
2020-06-01 |
| COVID-OLFA: Diagnostic Value Of Patient-reported And Clinically Verified Olfactory Disorders (COVID-19 Olfactory Assessment) |
Ageusia, Coronavirus disease 19 infection, Dysomia |
ELISA test alone, RT-PCR test alone, simple olfactory CODA test alone, swabbing alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital, Montpellier |
|
France |
2020-03-01 |
2020-04-30 |
COVID-OLFA, NCT04407494, RECHMPL20_0176 |
Phase Not Applicable |
Completed |
0 |
2 Months |
809 |
Fréderic VENAIL, PU-PH |
2020-06-01 |
| QoL and the Emotional-affective Sphere in Rehabilitation Setting During COVID-19 Quarantine |
Coronavirus disease 19 infection, Musculoskeletal disease, Neurological disease |
rehabilitation alone, social distancing alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fondazione Don Carlo Gnocchi - Onlus |
|
Italy |
2020-05-25 |
2020-08-31 |
FDG_SOCIALDISTANCING_COVID-19, NCT04408196 |
Phase Not Applicable |
Not yet recruiting |
0 |
3 Months |
200 |
IRENE APRILE, MD,PHD, Irene APRILE, MD,PHD |
2020-06-01 |
| Seroepidemiological Study of SARS-CoV-2 (COVID-19) Infection in Population Subgroups in the State of Sao Paulo |
Coronavirus disease 19 infection |
biological sampling alone, polymerase chain reaction alone, serological test alone |
|
Healthy volunteers accepted, Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Instituto Butantan |
|
Brazil |
2020-06-01 |
2020-07-30 |
COVID-19-EPI-01, NCT04408014 |
Phase Not Applicable |
Not yet recruiting |
1 |
1 Month |
18901 |
Alexander R Precioso, MD, PhD |
2020-06-01 |
| A randomized, double-blind, placebo-controlled study to evaluate whether prophylaxis with RTB-101 as compared to placebo reduces the severity of laboratory-confirmed COVID-19 in adults 65 years of age and older who reside in a nursing home |
Coronavirus disease 19 infection |
dactolisib alone |
Phosphoinositide 3-kinase inhibitor, mTOR complex 1 inhibitor, mTOR complex 2 inhibitor |
Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
resTORbio Inc |
Brown University School of Public Health, Genesis HealthCare System, Insight Therapeutics, LLC |
|
|
|
|
Phase Not Applicable |
Not yet recruiting |
0 |
|
550 |
|
2020-06-01 |
| Awake Proning in COVID-19 Patients With Hypoxemic Respiratory Failure |
Coronavirus disease 19 infection, Hypoxia, Respiratory failure |
awake prone positioning alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Columbia University |
|
US |
2020-04-16 |
2021-05-31 |
AAAT0134, NCT04408222 |
Phase Not Applicable |
No longer recruiting |
0 |
13 Months |
29 |
Sanja Jelic, MD |
2020-06-01 |
| Safety and Efficacy of Viusid and Asbrip in Hospitalized Patients Infected by SARS-Cov-2 With COVID-19 |
Coronavirus disease 19 infection, Respiratory disease, Viral pneumonia |
standard of care alone, Asbrip plus Viusid |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Catalysis SL |
|
Ecuador |
2020-05-04 |
2020-06-15 |
IESS-HTMC-JUTD-2020-0305-M, NCT04407182 |
Phase 2 Clinical |
Recruiting |
0 |
1 Month |
60 |
Mario Mero, Dr, Mario Mero, Dr., Martha Heras Veloz, Martha Heras Veloz, Dr, Martha Heras Veloz, Dr., Wilson Benites I., Dr, Wilson Benites I., Dr. |
2020-06-01 |
| A phase II, randomized, double-blind, placebo-controlled trial to evaluate the safety, tolerability, pharmacokinetics and efficacy of OP-101 in patients with severe COVID-19 |
Coronavirus disease 19 infection |
OP-101 alone, standard of care alone |
|
|
Orpheris Inc |
|
US |
|
|
|
Phase 2 Clinical |
Not yet recruiting |
1 |
|
|
|
2020-06-01 |
| SOLID: Study of the Immunity of Patients With Lung Cancer and COVID-19 Infection |
Coronavirus disease 19 infection, Lung tumor |
ELISA alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fundación GECP |
|
Spain |
2020-04-15 |
2020-09-15 |
GECP 20/04_SOLID, NCT04407143, SOLID |
Phase Not Applicable |
Recruiting |
66 |
5 Months |
1000 |
Adriana Rosero, MD, Airam Padilla, MD, Alfonso Gúrpide, MD, Amelia Insa, MD, Ana Blasco, MD, Ana Laura Ortega, MD, Ana López, MD, Ana Reyes, MD, Anna Estival, MD, Antonio Calles, MD, Beatriz Esteban Herrera, MD, Beatriz Esteban, MD, Beatriz Jiménez, MD, Carlos Camps, MD, Carlos García, Carlos García, MD, Clara Gonzálvez, MD, Clara Lucía Gonzálvez, MD, Claudio Ávila, MD, Delvys Rodríguez, MD, Edel del Barco, MD, Ernest Nadal, MD, Esperanza Arriola, MD, Eugenio Palomares, MD, Eva Pereira, Gloria Ma Serrano, MD, Gloria Mª Serrano, MD, Hospital Universitario de Canarias, Hugo Arasanz, MD, Hugo Arazanz, MD, Inmaculada Maestu, MD, Isabel Manrique, MD, Isidoro Barneto, MD, Javier Afonso Afonso, MD, Javier Afonso, MD, Javier Garde, MD, Javier Pérez, MD, Javier de Castro, MD, Jesús Corral, MD, Joaquim Bosch, Joaquim Bosch, MD, Jose García Sánchez, MD, Josefa Terrassa, MD, José García, MD, José Luis López, MD, Juan Coves, Juan Coves, MD, Juan Felipe, MD, Juana Oramas, MD, Judit Rubio, MD, Karmele Areses, MD, Laia Capdevila, MD, Luis Enrique Chara Velarde, MD, Luís Cabezón, MD, MAría González, MD, Ma Pilar Diz, MD, Ma Ángeles Moreno, MD, Manuel Cobo, Manuel Cobo, MD, Manuel Dómine, MD, Manuel Fernández, MD, Margarita Majem, MD, Maria Guirado, MD, Mariano Provencio, MD, Martín Lázaro, MD, María González, MD, María Sereno, MD, Mª Pilar Diz, MD, Mª Ángeles Moreno, MD, Mónica Serrano, MD, Noemí Reguart, MD, Oscar Juan-Vidal, Oscar Juan-Vidal, MD, Rafael López, Rafael López, MD, Raquel Cervera, MD, Reyes Bernabé, Reyes Bernabé, MD, Rosa María Vilaltoro, MD, Rosa María Villatoro, MD, Rosario García, MD, Rubén Alonso Calderón, MD, Rubén Alonso, MD, Santiago Ponce, MD, Sara Cerezo, MD, Sergio Vázquez, MD, Teresa de Portugal, MD, Unai Jiménez, MD, Xabier Mielgo, MD |
2020-06-02 |
| COVID-19 and Mental Health |
Coronavirus disease 19 infection, Psychiatric disorder |
online survey alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Northeastern University |
|
US |
2020-06-01 |
2021-06-01 |
20-05-22, NCT04407195 |
Phase Not Applicable |
Not yet recruiting |
0 |
12 Months |
2000 |
Kara Pavone, Kara Pavone, PhD |
2020-06-02 |
| Change in the Ratio of Mean Platelet Volume (MPV) to Platellet(PLT) in Covid-19 Pneumonia Patients |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Gaziosmanpasa Taksim Research and Education Hospital |
|
Turkey |
2020-06-05 |
2020-08-20 |
69, NCT04408378 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
156 |
aygen türkmen, MD.prof., zuhal çavuş, MD |
2020-06-02 |
| STACOV: Statin Therapy And Covid-19 Infection |
Coronavirus disease 19 infection |
statin therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Institut Investigacio Sanitaria Pere Virgili |
|
Spain |
2020-05-14 |
2020-06-30 |
106/2020, NCT04407273, STACOV |
Phase Not Applicable |
Recruiting |
7 |
1 Month |
1200 |
Lluís Masana, Dr, Luis Masana, MD, PhD |
2020-06-02 |
| A clinical study of SARS-CoV-2 vaccine (VLP, COVID-19) for the potential prevention of SARS-CoV-2 infection (COVID-19) |
Coronavirus disease 19 infection |
SARS-CoV-2 vaccine (VLP, COVID-19), Medicago alone |
|
|
Medicago Inc |
|
US |
2020-08-31 |
|
|
Phase Not Applicable |
Status not specified |
0 |
|
|
|
2020-06-02 |
| CRITICoVid: Prevalence of Critical Forms of CoVid-19 in Patients With Chronic Respiratory Disease |
Asthma, Bronchus disease, Chronic obstructive pulmonary disease, Coronavirus disease 19 infection, Cystic fibrosis, Dyspnea, Obesity hypoventilation syndrome, Obstructive sleep apnea, Pulmonary hypertension, Respiratory disease |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Central Hospital, Nancy, France |
|
|
2020-06-01 |
2020-08-01 |
2020PI081, CRITICoVid, NCT04407169 |
Phase Not Applicable |
Not yet recruiting |
0 |
2 Months |
500 |
simon valentin, MD |
2020-06-02 |
| ANOSIRM: Brain MRI Imaging in Patients With SARS-Cov2 (COVID-19) Infection With or Without Anosmia |
Coronavirus disease 19 infection, Dysomia |
brain MRI scan alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire de Nimes |
|
France |
2020-06-30 |
2020-12-31 |
ANOSIRM, NCT04408391, NIMAO/2020-01/BL-001 |
Phase Not Applicable |
Not yet recruiting |
1 |
6 Months |
40 |
Anissa Megzari, Benjamin Lallemant, Caroline Alovisetti, Fabricio Pereira, Jean-Paul Beregi, Nicolas Menjot de Champfleur |
2020-06-02 |
| Appendicitis During the National Lockdown During the COVID-19 Pandemic |
Appendicitis, Coronavirus disease 19 infection |
Lock-down and social distancing alone |
|
|
Nordsjaellands Hospital |
|
Denmark |
2017-03-23 |
2020-04-19 |
APPCOVID-19, NCT04407117 |
Phase Not Applicable |
Completed |
1 |
36 Months |
6000000 |
Claus A Bertelsen, PhD |
2020-06-02 |
| NR-COVID19: Effects of Nicotinamide Riboside on the Clinical Outcome of Covid-19 in the Elderly |
Coronavirus disease 19 infection |
nicotinamide riboside alone |
|
Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Copenhagen University |
Bispebjerg Hospital |
Denmark |
2020-06-01 |
2022-05-01 |
H-20026601, NCT04407390, NR-COVID19 |
Phase 2 Clinical |
Recruiting |
1 |
23 Months |
100 |
Celeste Porsbjerg, MD/PhD, Morten Scheibye-Knudsen, Morten Scheibye-Knudsen, MD/DMSc(PhD) |
2020-06-02 |
| COVIDHELP: COVID-19 in Cancer Patients: Evaluation of Clinical Course and Impact on Oncological Care Including Biobanking |
Cancer, Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universitätsklinikum Hamburg-Eppendorf |
Universitatsklinikum Schleswig-Holstein Campus Kiel, Universitatsklinikum Schleswig-Holstein Campus Lubeck |
Germany |
2020-04-15 |
2022-04-14 |
COVIDHELP, NCT04408339, PV7313 |
Phase Not Applicable |
Recruiting |
2 |
24 Months |
500 |
Katja Weisel, MD, Niklas Boerschel, MD, S Guengoer |
2020-06-02 |
| Role of Children in Transmission of COVID-19 to Immunocompromised Patients |
Coronavirus disease 19 infection, Immune disorder |
blood sampling alone, mid-turbinate swab sampling alone, saliva sampling alone |
|
Healthy volunteers accepted |
Jonsson Comprehensive Cancer Center |
National Cancer Institute |
US |
2020-05-28 |
2023-05-28 |
20-000517, NCT04407546 |
Phase Not Applicable |
Not yet recruiting |
0 |
36 Months |
300 |
Ashley Gray, M.D., Grace Aldrovandi, M.D. |
2020-06-02 |
| Use of Convalescent Plasma for COVID-19 |
Coronavirus disease 19 infection, Respiratory failure, Tachypnea |
convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Northside Hospital, Inc. |
|
US |
2020-06-30 |
2022-06-30 |
NCT04408040, NSH 1281 |
Phase 2 Clinical |
Not yet recruiting |
0 |
24 Months |
700 |
Kent Holland, MD, Stacey Brown |
2020-06-02 |
| AKI Biomarkers in COVID-19 |
Coronavirus disease 19 infection, Renal injury, Respiratory disease |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Guy's & St Thomas' Hospital NHS Trust |
University Hospital Muenster |
UK |
2020-06-01 |
2021-06-30 |
283675, NCT04408248 |
Phase Not Applicable |
Not yet recruiting |
0 |
13 Months |
30 |
Marlies Ostermann, MD, PhD, Nuttha Lumlertgul, MD, PhD |
2020-06-01 |
| VANGARD: VIP ANalogue, in hospitalized COVID-19 patients at hiGh risk for rapid clinical deterioration and ARDS |
Coronavirus disease 19 infection, Respiratory distress syndrome |
PB-1046 alone |
VIP 2 receptor agonist |
|
PhaseBio Pharmaceuticals Inc |
|
US |
2020-06-30 |
|
VANGARD |
Phase 2 Clinical |
Planned |
0 |
|
210 |
|
2020-06-01 |
| A prospective open-label study of the efficacy and safety of the use of the drug Tigerase as part of complex therapy in patients with COVID-19 |
Coronavirus disease 19 infection |
GNR-039 alone |
Deoxyribonuclease I stimulator |
|
CJSC Generium |
|
Russian Federation |
2020-06-01 |
2020-11-30 |
DRN-ALI-III |
Phase 3 Clinical |
Status not specified |
6 |
6 Months |
150 |
|
2020-06-01 |
| Exploratory, open-label study of the efficacy and safety of the use of the drug Elizaria as part of complex therapy in patients with severe and extremely severe COVID-19 course |
Coronavirus disease 19 infection |
eculizumab biosimilar, IBC GENERIUM alone |
Complement C5 factor inhibitor |
|
CJSC Generium |
|
Russian Federation |
2020-06-01 |
2020-12-31 |
ECU-ALI-III |
Phase 3 Clinical |
Status not specified |
7 |
7 Months |
150 |
|
2020-06-02 |
| Research study to evaluate the impact of Selected Ayurvedic interventions in containment zone |
Coronavirus disease 19 infection |
Guduchi Ghan Vati/ Sudarshan Ghan Vati alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Central Council for Research in Ayurvedic Sciences, Ministry of Ayush |
|
India |
2020-06-01 |
|
CTRI/2020/05/025385 |
Phase Not Applicable |
Not yet recruiting |
0 |
|
40000 |
Dr Anil Avhad, Dr C Muralikrishna, Dr DSRotwar, Dr Deepa Sharma, Dr K Prameela Devi, Dr Kuldeep, Dr PL Bharati, Dr Paikrao Sumed, Dr Ranjita Ekka, Dr SH Doddamani, Dr Sandip Kumar Ramjivan Baheti, Dr Sanjay Kumar, Dr Savita Sharma, Dr Sneha Marlewar, DrAlok Kumar Srivastava, DrKavita Mansukhbhai Vyas, DrVilas Gangurde, Prof KS Dhiman, SK Vedi, Suhas A Chaudhary, Vipin Sharma |
2020-06-01 |
| A study to evaluate the effect and safety of a phytopharmaceutical drug in treatment of Coronavirus infection |
Coronavirus disease 19 infection |
purified aqueous extract of Cocculus hirsutus alone |
|
|
Sun Pharmaceutical Industries Ltd |
|
India |
2020-06-01 |
|
CTRI/2020/05/025397, Secondary ID Registry ICR/20/005, Version No. 1.0 |
Phase 2 Clinical |
Not yet recruiting |
14 |
|
210 |
Dr Amit Dhamija, Dr Apurva Agarwal, Dr Bhattachrya Meenakshi, Dr D Anil Kumar, Dr Harish Gupta, Dr K Vengadakrishnan, Dr Khobragade Akash Ashokkumar, Dr Maulik Doshi, Dr Md Sabah Siddiqui, Dr Parvaiz Koul, Dr Rajadhyaksha Girish Chandrakant, Dr Rakesh Patil, Dr Rohit Parate, Dr Shilpi Dhawan, Dr Shivakumar Sankaranarayanan Iyer, Dr Sushila Kataria, Guruprasad Palekar |
2020-06-01 |
| Study to find out the results of Ayurvedic Kwath & Ashwagandha churna with Yoga exercises to prevent our health workers against corona virus infection |
Coronavirus disease 19 infection |
Kiratiktadi Kwath & Ashwagandha churna alone, Yoga exercises alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
GS Ayurveda Medical College & Hospital |
|
India |
2020-05-28 |
|
CTRI/2020/05/025398 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
30 |
Prof Dr Ankur Singhal |
2020-06-01 |
| Pregnancy and COVID-19 Registry |
Coronavirus disease 19 infection |
|
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
ICMR National Institute for Research in Reproductive Health, Medical Education and Drugs Department |
|
India |
|
|
CTRI/2020/05/025423 |
Phase Not Applicable |
Not yet recruiting |
2 |
|
2000 |
Dr Niraj Mahajan, Dr Rahul Gajbhiye, Dr Rakesh Waghmare |
2020-06-01 |
| Clinical features and outcome of COVID-19 and non-COVID respiratory infection |
Coronavirus disease 19 infection, Respiratory tract infection, Viral pneumonia |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) |
Christian Medical College, Vellore, India |
|
India |
2020-06-04 |
|
CTRI/2020/05/025424 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Leni G Mathew |
2020-06-01 |
| Ayurvedic intervention (Chyawanprash) in the prevention of COVID-19 pandemic among Health Care Personnel |
Coronavirus disease 19 infection |
Chayavanprash alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Central Council for Research in Ayurvedic Sciences |
Ministry of Ayush |
India |
2020-06-02 |
|
CTRI/2020/05/025425 |
Phase 4 Clinical |
Not yet recruiting |
1 |
|
50 |
Dr BabitaYadav, Dr Nitin Jindal, Dr Shivshankar Rajput |
2020-06-01 |
| SCB-2019 as COVID-19 Vaccine |
Coronavirus disease 19 infection |
SCB-2019 alone, Variable regimens including AS03 adjuvant , CpG 1018 adjuvant , SCB-2019 , alum adjuvant |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Clover Biopharmaceuticals AUS Pty Ltd |
|
|
2020-06-20 |
2021-03-30 |
CLO-SCB-2019-001, NCT04405908 |
Phase 1 Clinical |
Not yet recruiting |
0 |
9 Months |
150 |
Min Dong |
2020-06-01 |
| Clinical Characteristics and Outcomes of Patients Admitted with Severe Acute Respiratory Illness |
Coronavirus disease 19 infection, Respiratory disease |
|
|
|
Mazumdar Shaw Medical Foundation |
|
India |
2020-05-30 |
|
CTRI/2020/05/025427 |
Phase Not Applicable |
Not yet recruiting |
9 |
|
200 |
Amarja Havaldar, Chandan, Dr Murthy, Farookh Khan, Gagan Brar, Jose Chacko, Rajesh Shetty, Shashidhar, Venkatesh Gupta |
2020-06-02 |
| CLIPSI study: COVID -19 Pandemic and Lockdown : Impact on Parents Stress level, Infant care and follow-up |
Acute stress disorder, Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Newborn Infants (up to 5 months) |
Sri Ramachandra Institute of Higher Education and Research |
|
India |
2020-05-29 |
|
CLIPSI study, CTRI/2020/05/025428 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
300 |
Usha Devi R |
2020-06-01 |
| Prediction of Acute Kidney Injury in Patients With COVID-19 |
Coronavirus disease 19 infection, Renal injury, Respiratory distress syndrome |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Muenster |
|
Germany |
2020-05-25 |
2021-03-31 |
04-ANIT-20, NCT04406688 |
Phase Not Applicable |
Not yet recruiting |
1 |
10 Months |
300 |
Alexander Zarbock, MD, Melanie Meersch, MD |
2020-06-01 |
| Effect of Ashwagandha (Withania somnifera) as a prophylactic measure among high risk population (Health Care Workers/Containment Zone Population) exposed to COVID-19 |
Coronavirus disease 19 infection |
Ashwagandha capsule alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Central Council for Research in Ayurveda and Siddha |
|
India |
2020-10-06 |
|
CTRI/2020/05/025429 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
5000 |
Dr PVV Prasad, Dr T Saketh Ram |
2020-06-01 |
| To evaluate the safety and tolerability of Cytokine cocktail therapy in healthy volunteers from healthy donors |
Coronavirus disease 19 infection, Viral infection |
Cytokine cocktail therapy alone, Interferon-gamma [INF-γ] alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
HealthCare Global Enterprises Ltd, International Stemcell Services Limited |
|
India |
|
|
CTRI/2020/05/025432, IMD/CoV/004/2020 |
Phase 1 Clinical |
Not yet recruiting |
1 |
|
6 |
Dr Ashish Dhoot, Dr Vishal Rao, Meena Dalal |
2020-06-01 |
| Evaluation the anti-inflammatory effects of curcumin in the treatment of patients with COVID-19 |
Coronavirus disease 19 infection |
common therapeutic protocol alone, nano-curcumin alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Ahvaz University of Medical Sciences |
|
Iran |
2020-06-05 |
|
IR.AJUMS.REC.1399.176, IRCT20200519047510N1 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
60 |
Ali Asadirad, Mohammad Badavi, Roohangiz Nashibi |
2020-06-01 |
| Prevention of Infection and Incidence of COVID-19 in Medical Personnel Assisting Patients With New Coronavirus Disease |
Coronavirus disease 19 infection |
bromhexine hydrochloride alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Almazov Federal Center of Heart, Blood and Endocrinology |
|
Russian Federation |
2020-05-14 |
2020-09-30 |
05-20-02-С, NCT04405999 |
Phase 4 Clinical |
Recruiting |
1 |
4 Months |
140 |
Evgeny Mikhailov, MD, PhD, Evgeny Shlyakhto, MD, PhD, Tamara Lyubimtseva, MD |
2020-06-02 |
| CONFI-LOMB: Confinement Effect on Low Back Pain Intensity in Chronic Low Back Pain Patients |
Coronavirus disease 19 infection, Lower back pain |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital, Angers |
|
France |
2020-06-02 |
2020-06-21 |
CONFI-LOMB, CONFI-LOMB, NCT04406363 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
300 |
Audrey Petit, PhD |
2020-06-02 |
| This Study Examines the Use of Disinfectants by Egyptian Women During the Coronavirus Lockdown and How They Seak Medical Advice for Adverse Reactions Related to the Use of Disinfectants |
Coronavirus disease 19 infection, Toxicity |
disinfectant usage alone, online survey alone |
|
Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Helwan University |
University of Nebraska |
Egypt |
2020-05-31 |
2020-07-01 |
COVID2020_HELWANU_01, NCT04405284 |
Phase Not Applicable |
Not yet recruiting |
1 |
1 Month |
100 |
Maha M Farid, PhD, Wael M ElRayes, PhD |
2020-05-29 |
| COVADO: Psychological Impact of the Health Measures Generated by the COVID19 in Adolescents |
Coronavirus disease 19 infection, Psychiatric disorder |
interview alone |
|
Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Centre Hospitalier Intercommunal Creteil |
|
France |
2020-05-27 |
2020-11-30 |
COVADO, COVADO, NCT04406558 |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
400 |
Adele CARLIER-GONOD, MD, Camille JUNG, MD PhD |
2020-06-02 |
| A study on treatment of COVID-19 patients with study drug along with standard of care |
Coronavirus disease 19 infection |
standard of care alone, tocilizumab alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Medanta The Medicity |
|
India |
2020-05-27 |
|
CTRI/2020/05/025369, TCZ/COVID-19/01/2020 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
180 |
Dr Arvinder Soin, Dr Pooja Sharma, Kuldeep K Chauhan |
2020-06-01 |
| A follow up research of exercise, cardiopulmonary and quality of Life for patients of novel coronavirus pneumonia |
Coronavirus disease 19 infection |
pulmonary rehabilitation program alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Anhui Provincial Hospital |
|
China |
2020-05-01 |
2021-05-20 |
ChiCTR2000033319 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
85 |
Ming Wu, Yang Zhang |
2020-06-02 |
| Evaluation of Role of Ayurvedic Drug- Guduchi Ghan Vati in the treatment of COVID-19 related illness |
Coronavirus disease 19 infection |
uduchi Ghan Vati alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Dr.S R.Rajasthan Ayurved University Jodhpur |
|
India |
2020-06-04 |
|
CTRI/2020/05/025370 |
Phase Not Applicable |
Not yet recruiting |
2 |
|
40 |
DR SANJAY SRIVASTAVA, Prof Dr Abhimanyu Kumar |
2020-06-01 |
| ArcHIV - SARS-CoV-2 IgG: Study platform ArcHIV - Substudy on SARS-CoV-2 (COVID-19) IgG antibody prevalence in an HIV cohort |
Coronavirus disease 19 infection, HIV infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
MUC Research GmbH |
Lab4More GmbH |
Germany |
2020-05-29 |
|
13112 Substudie zu ArcHIV Studienplattform, ArcHIV - SARS-CoV-2 IgG, DRKS00021737, DRKS00021752 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
500 |
Celia Jonsson-Oldenbüttel, Eva Wolf, Sebastian Noe |
2020-06-02 |
| Retrospective Assessment of Treatments of Hospitalized COVID19 Patients |
Coronavirus disease 19 infection |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
ARC Ventures |
|
India |
2020-06-02 |
|
CTRI/2020/05/025371 |
Phase Not Applicable |
Not yet recruiting |
2 |
|
500 |
Dr Deepa Divekar, Dr Ravindra Ghooi, Dr Sundeep Salvi |
2020-06-01 |
| Epidemiological and Clinical Characteristics of 20 Re-positive novel coronavirus pneumonia (COVID-19) Patients |
Coronavirus disease 19 infection |
anti-virus treatment alone |
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Affiliated Hospital of Zunyi Medical College |
The Science and Technology Department of Guizhou Province |
China |
2020-01-29 |
2020-04-30 |
ChiCTR2000033347 |
Phase 1 Clinical |
No longer recruiting |
1 |
3 Months |
20 |
Zhang Wei |
2020-06-01 |
| Erythrocyte Sedimentation Rate in novel coronavirus pneumonia (COVID-19) patients |
Coronavirus disease 19 infection |
|
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Affiliated Hospital of Zunyi Medical College |
The Science and Technology Department of Guizhou Province |
China |
2020-02-29 |
2020-05-12 |
ChiCTR2000033346 |
Phase 1 Clinical |
No longer recruiting |
1 |
2 Months |
80 |
Zhang Wei |
2020-06-01 |
| Proof of concept research project to demonstrate the improved transfection by using Nuvec used as a delivery system using a Covid-19 DNA plasmid |
Coronavirus disease 19 infection |
Covid-19 DNA plasmid alone, Nuvec alone |
|
|
N4 Pharma plc |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
|
|
2020-06-01 |
| CA-COVID19: Coagulopathy in COVID19 - A Multicenter, Observational Study in UK (COVID19) |
Bleeding, Coronavirus disease 19 infection, Thrombosis |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Imperial College London |
|
UK |
2020-05-21 |
2021-06-20 |
20SM5934, CA-COVID19, NCT04405232 |
Phase Not Applicable |
Recruiting |
1 |
13 Months |
5000 |
Dr Deepa Jayakody Arachchillage, FRCPath, MD |
2020-06-01 |
| Study for the effect of Traditional Chinese medicine in the prevention of novel coronavirus pneumonia (COVID-19) in the high risk area |
Coronavirus disease 19 infection |
Chushifangyi prescription alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Affiliated Hospital of Changchun University of Traditional Chinese Medicine |
|
China |
2020-05-29 |
2020-12-31 |
ChiCTR2000033345 |
Phase Not Applicable |
Not yet recruiting |
1 |
7 Months |
10000 |
Liu Yangyang, Shi Li |
2020-06-01 |
| Efficacy of Liu-zi-jue in Patients with 2019 Novel Coronavirus Pneumonia (COVID-19): a randomized controlled trial |
Coronavirus disease 19 infection, Viral pneumonia |
Liu--zi-jue alone, conventional treatment alone |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shanghai University of Traditional Chinese Medicine, Yueyang Xinhua Pharmaceutical Co Ltd |
|
China |
2020-02-20 |
2020-12-30 |
ChiCTR2000033318 |
Phase Not Applicable |
Recruiting |
1 |
10 Months |
104 |
Min Fang, Shuaigpan Zhang |
2020-06-01 |
| The Effect of EIDD-2801 on Viral Shedding of SARS-CoV-2 |
Coronavirus disease 19 infection, Dysomia, Viral pneumonia |
EIDD-2801, Drug Innovation Ventures/Georgia State University/Emory University alone |
RNA polymerase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ridgeback Biotherapeutics LP |
|
|
2020-05-26 |
2020-07-13 |
EIDD-2801-2004, NCT04405739 |
Phase 2a Clinical |
Not yet recruiting |
0 |
1 Month |
80 |
Laura Szewczyk |
2020-06-01 |
| Clinical Scores for Outcome Prediction in Patients With Severe COVID-19 Pneumonia Requiring ECMO |
Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia |
veno-venous extracorporeal membrane oxygenation therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Klinikum der Albert-Ludwigs Universitaet Freiburg |
|
Germany |
2020-05-19 |
2020-08-31 |
EK-FR 329/20, NCT04405973 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
100 |
Alexander Supady, Dr., MPH, Alexander Supady, MD, MPH, Dawid Staudacher, MD |
2020-06-01 |
| Determination of Acute Encephalopathy Predictors in Patients With COVID-19 |
Brain disease, Coronavirus disease 19 infection, Viral pneumonia |
Blood test alone, Electroencephalography alone, Pulse oximetry alone, chest CT-scan alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Ministry of Health and Social Development of the Russian Federation, Pirogov National Medical Surgical Center |
|
Russian Federation |
2020-05-22 |
2020-10-22 |
NCT04405544, NMSC-01-20 |
Phase Not Applicable |
Recruiting |
1 |
5 Months |
60 |
Oleg I Vinogradov, MD, PhD |
2020-06-02 |
| COVICLOT: Thromboembolic Events in Severe COVID-19 Patients |
Coronavirus disease 19 infection, Thromboembolism |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hopitaux Universitaires de Strasbourg |
|
France |
2020-04-29 |
2021-04-30 |
7779, COVICLOT, NCT04405869 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
300 |
Alexandre GODON, MD, Alexandre MANSOUR, MD, Anne Claude ROCHE, MD, Anne GODIER, MD, PhD, Annick STEIB, MD, PhD, Bélaïd BOUHEMAD, MD, PhD, Charles TACQUARD, MD, Cécile AUBRON, MD, PhD, Delphine GARRIGUE, MD, Eric KIPNIS, MD, PhD, Isabelle GOUIN-THIBAULT, MD, Julien POISSY, MD, PhD, Lea RYFFEL, MD, Maxime NGUYEN SOENEN, MD, Pierre ALBALADEJO, MD, PhD, Saïd CHAYER, PhD, HDR, Sophie SUSEN, MD, PhD, Stephan MANKIKIAN, MD |
2020-06-02 |
| A Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Baicalein in Hospitalized Adult Patients With Mild and Moderate 2019-nCoV Respiratory Disease |
Coronavirus disease 19 infection |
Baicoli alone, standard therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Chinese Academy of Medical Sciences & Peking Union Medical College, Xiangyang Central Hospital |
|
China |
2020-02-15 |
2020-03-09 |
ChiCTR2000033286 |
Phase 2/Phase 3 Clinical |
Completed |
2 |
|
60 |
Chaoqing Wang, Xiansheng Zeng |
2020-06-01 |
| COZI: COVID-19 Ozanimod Intervention Study |
Coronavirus disease 19 infection, Hypoxia, Viral pneumonia |
anticoagulation therapy alone, antipyretics agent therapy alone, antiviral agent therapy alone, corticoid therapy alone, fluid resuscitation alone, immunomodulator therapy alone, ozanimod alone, standard of care alone |
Sphingosine-1-phosphate receptor-1 agonist, Sphingosine-1-phosphate receptor-5 agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Universite Laval |
Bristol-Myers Squibb Co, Celgro Corp |
Canada |
2020-07-06 |
2022-07-06 |
2021-3474, COZI, NCT04405102 |
Phase 2 Clinical |
Not yet recruiting |
2 |
24 Months |
48 |
David Marsolais, PhD, Francois Lellouche, Francois Lellouche, MD, Nathalie Chateauvert, B. pharm, Pascale Blais-Lecours, PhD |
2020-06-01 |
| 'Pirfenidone XR as a protector in patients with COVID-19' |
Coronavirus disease 19 infection |
pirfenidone XR alone |
|
|
Instituto Nacional de Ciencias Medicas y Nutricion |
|
Mexico |
|
|
3381 |
Phase 3 Clinical |
Status not specified |
1 |
|
801 |
|
2020-06-01 |
| A clinical trial to evaluate the Medicinal effects of ZingiVir-H as Anti-Viral therapy in COVID-19 patients |
Coronavirus disease 19 infection |
NSAID alone, standard of care alone, Variable regimens including HgS and As2S3 , Vitamin C , Zinc , Zingivr-H , oxygen |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Pankajakasthuri Ayurveda Medical College and Post Graduate Center |
|
India |
2020-05-31 |
|
CTRI/2020/05/025434 |
Phase 4 Clinical |
Not yet recruiting |
3 |
|
135 |
Dr Anita Ajit Saibannavar, Dr Madhukumar, Dr Shan Sasidharan, DrJHareendran Nair, Sri Venkateshwara hospitals |
2020-06-01 |
| The comprehensive evaluation of therapeutic drugs for pediatric novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection |
traditional Chinese medicine alone |
|
|
Children's Hospital of Fudan University |
|
China |
2020-06-15 |
2020-11-30 |
ChiCTR2000033342 |
Phase Not Applicable |
Not yet recruiting |
12 |
5 Months |
100 |
Zhiping Li |
2020-06-01 |
| IMPACT: Anticoagulation in Critically Ill Patients With COVID-19 |
Blood clotting disorder, Coronavirus disease 19 infection |
argatroban alone, enoxaparin sodium alone, fondaparinux sodium alone, unfractionated heparin alone |
Factor IIa antagonist, Factor Xa antagonist, Low molecular weight heparin |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Weill Medical College of Cornell University |
|
US |
2020-06-30 |
2021-06-30 |
20-04021936, IMPACT, NCT04406389 |
Phase 4 Clinical |
Not yet recruiting |
1 |
12 Months |
186 |
Maria T DeSancho, MD, MSc, Marina Loizou |
2020-06-01 |
| Severe Reluctant COVID-19 Patients Responding to Convalescent Plasma; A case series |
Coronavirus disease 19 infection |
convalescent plasma therapy alone |
|
Middle-aged Adults (45-64 yrs) |
University of Sulaimani |
|
Iraq |
2020-05-11 |
2020-05-19 |
ChiCTR2000033323 |
Phase Not Applicable |
No longer recruiting |
1 |
|
24 |
Fahmi Hussein Kakamad, Rawezh qadr |
2020-06-01 |
| The Effectiveness of Telerehabilitation-Based Physiotherapy in COVID 19 Patients |
Coronavirus disease 19 infection |
telerehabilitation physical therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Istanbul Medipol University Hospital |
Saglik bilimleri universtesi |
Turkey |
2020-05-20 |
2020-12-01 |
NCT04402983, TELEREHAB_COVID19 |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
34 |
Esra Pehlivan, PhD |
2020-06-01 |
| Study for Traditional Chinese Medicine in the treatment of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Traditional Chinese Medicine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Shuguang Hospital Shanghai University Of Traditional Chinese Medicine |
Shanghai Committee of Science and Technology |
China |
2020-03-27 |
2020-12-31 |
ChiCTR2000033320, ChiMCTR2000003347 |
Phase 0 Clinical |
Recruiting |
1 |
9 Months |
300 |
Zhang Wei |
2020-06-01 |
| Viral Specific T-cells for Treatment of COVID-19 |
Coronavirus disease 19 infection |
viral specific T-cells alone |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cincinnati Children's Hospital Medical Center |
Hoxworth Blood Center |
US |
2020-06-30 |
2025-06-30 |
2020-0353, NCT04406064 |
Phase 2 Clinical |
Not yet recruiting |
1 |
60 Months |
100 |
Adam Nelson, MBBS, FRACP, Celeste Dourson, MS, Jamie Wilhelm, BS |
2020-06-01 |
| Survival and risk factors in COVID-19 and influenza, a retrospective analysis |
Coronavirus disease 19 infection, Influenza virus infection |
|
|
|
Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie (DE) |
Universitat des Saarlandes |
Germany |
2020-05-29 |
|
78/20, DRKS00021823 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
18000 |
Mr. Prof. Dr. Sascha Kreuer |
2020-06-01 |
| Home-Based Covid-19 Rehabilitation Program |
Coronavirus disease 19 infection |
PT-Pal guided exercise alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Albert Einstein College of Medicine |
|
US |
2020-07-01 |
2021-03-01 |
2020-11535, NCT04406532 |
Phase Not Applicable |
Not yet recruiting |
1 |
8 Months |
100 |
Anne F Ambrose, MD, Emmeline Ayers, MPH, Joe Verghese, MBBS |
2020-06-01 |
| Stellate Ganglion Block (SGB) for COVID-19 Acute Respiratory Distress Syndrome (ARDS) |
Coronavirus disease 19 infection, Respiratory distress syndrome |
Stellate Ganglion Block alone, Variable regimens including bupivacaine, AstraZeneca , dexamethasone , lidocaine |
Sodium channel inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
West Virginia University |
|
US |
2020-04-24 |
2020-12-31 |
2004963113, NCT04402840 |
Phase 2 Clinical |
Recruiting |
1 |
8 Months |
5 |
Ali R Rezai, MD, Ali Rezai, Padma Tirumalai, PhD |
2020-06-01 |
| MEMO-COV2: COVID-19: SARS-CoV-2 Specific Memory B and T-CD4+ Cells |
Coronavirus disease 19 infection |
blood sampling alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assistance Publique Hopitaux de Paris |
|
France |
2020-06-01 |
2021-03-01 |
APHP200551, MEMO-COV2, NCT04402892 |
Phase Not Applicable |
Not yet recruiting |
1 |
9 Months |
60 |
MAHEVAS Matthieu, PHD |
2020-06-01 |
| Psychiatric admissions during the COVID-19 pandemic |
Coronavirus disease 19 infection, Psychiatric disorder |
psychological assessment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Prince of Wales Hospital |
|
China |
2020-05-25 |
2021-07-31 |
ChiCTR2000033317 |
Phase Not Applicable |
Not yet recruiting |
1 |
14 Months |
10000 |
Allen Ting Chun LEE |
2020-06-01 |
| ERap-COV: Evaluation of Rapid Diagnostic Solutions, Serological and Molecular Tests for COVID-19 |
Coronavirus disease 19 infection |
ELISA alone, rapid diagnostic test (NG Biotech) alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assistance Publique Hopitaux de Paris |
|
France |
2020-05-25 |
2021-03-25 |
APHP200556, ERap-COV, NCT04405492 |
Phase Not Applicable |
Not yet recruiting |
2 |
10 Months |
1210 |
Anne-Marie Roque-Afonso, Thierry Naas |
2020-06-01 |
| A clinical study to assess the efficacy of Neumifil in the treatment of patients with COVID-19 infection |
Coronavirus disease 19 infection |
Neumifil alone |
|
|
Pneumagen Ltd |
|
|
2021-06-30 |
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-05-29 |
| A multinational, double-blind, randomized, phase II clinical study to assess the effect of ATR-002 in the treatment of COVID-19 patients |
Coronavirus disease 19 infection |
ATR-002 alone |
MEK protein kinase inhibitor |
|
Atriva Therapeutics GmbH |
Evonik Industries AG |
|
2020-07-31 |
|
|
Phase 2 Clinical |
Planned |
0 |
|
|
|
2020-05-29 |
| CoviPrep Study: TAF/FTC for Pre-exposure Prophylaxis of COVID-19 in Healthcare Workers |
Coronavirus disease 19 infection |
emtricitabine + tenofovir alafenamide alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Hospital Italiano de Buenos Aires |
Sociedad Argentina de Infectología |
Argentina |
2020-06-15 |
2020-11-15 |
16052020, CoviPrep Study, NCT04405271 |
Phase 3 Clinical |
Not yet recruiting |
1 |
5 Months |
1378 |
Diego H Giunta, PhD, Elvira Zini, MD, Esteban Nannini, MD, Fernando Riera, MD, Gonzalo Corral, MD, Gustavo Costilla Campero, MD, Gustavo D Lopardo, MD, Marcelo Figueiras, MD, Omar Sued, MD, Santiago Ramirez Borga, MD, Ventura Simonovich, MD, Waldo H Belloso, MD, Wanda Cornistein, MD |
2020-06-01 |
| Study on the improvement the quality of life of severe patients with COVID-19 by the integrated treatment with Chinese medicine and Western medicine |
Coronavirus disease 19 infection |
chinese herbal medication alone, pirfenidone alone, traPirfenidone alone, traditional Chinese Medicine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Guangzhou Women and Children's Medical |
|
China |
2020-06-01 |
2025-05-31 |
ChiCTR2000033284 |
Phase 0 Clinical |
Not yet recruiting |
2 |
60 Months |
|
Zhang Shunxian |
2020-06-01 |
| Study of the Spread of COVID-19 in Saint Petersburg, Russia |
Coronavirus disease 19 infection |
SARS-CoV-2-specific antibodies test alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
European University at St. Petersburg |
Clinic “Scandinavia” (LLC Ava-Peter) |
Russian Federation |
2020-05-27 |
2020-10-28 |
CDRU-001, ISRCTN11060415, NCT04406038 |
Phase Not Applicable |
Recruiting |
1 |
5 Months |
1550 |
Anton Barchuk, MD, Daniil Shirokov, Dr Dmitriy Skougarevskiy, Lubov Barabanova, MD |
2020-06-02 |
| Monitoring COVID-19 Patients' Lung Fluid Using Impedance Technique |
Coronavirus disease 19 infection |
lung impedance technique alone, x-ray alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hillel Yaffe Medical Center |
|
Israel |
2020-04-28 |
2021-04-28 |
0059-20-HYMC, NCT04406493 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
50 |
Michael Cleiner, M.D, Michael Cleiner, M.D. |
2020-06-01 |
| CPC-SARS: Convalescent Plasma of Covid-19 to Treat SARS-COV-2 a Randomized, Doble-Blind, Two-Center Trial |
Coronavirus disease 19 infection, Hypoxia, Viral pneumonia |
Variable regimens including azithromycin , convalescent plasma , hydroxychloroquine |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Hospital General Naval de Alta Especialidad |
Instituto Nacional de Enfermedades Respiratorias, National Institute of Pediatrics |
Mexico |
2020-05-20 |
2020-07-20 |
CPC-SARS, DI/20/201/04/19, NCT04405310 |
Phase 2/Phase 3 Clinical |
Recruiting |
2 |
2 Months |
80 |
AMALIA BRAVO-LINDORO, MS, ANGEL A PEREZ-CALATAYUD, MD, ANGEL AUGUSTO PEREZ-CALATAYUD, MD, Angel Augusto Perez Calatayud, BALTAZAR PECH-ALONSO, MD, CARLOS CABELLO-GUTIERREZ, PHD, CARLOS PEÑA-PEREZ, MD, CATALINA CASILLAS-SUAREZ, PHD, EVELYN CORTINA-DE LA ROSA, MS, JOSE CARRILLO RUIZ, PhD, KARLA MALDONADO-SILVA, MD, ORLANDO CARILLO-TORRES, PHD, ORLANDO CARRILLO-TORRES, PHD, RAUL CARRILLO-ESPER, MD, SANDRA MURRIETA, MD, VERONICA FERNANDEZ-SANCHEZ, PHD, YANET VENTURA, MD, YANET VENTURA-ENRIQUEZ, MD |
2020-06-01 |
| Efficacy of Ivermectin in Adult Patients With Early Stages of COVID-19 |
Coronavirus disease 19 infection |
ivermectin alone |
Chloride channel modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centro de Estudios en Infectogía Pediatrica |
|
Colombia |
2020-06-30 |
2020-11-01 |
NCT04405843, SCDI823 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
4 Months |
400 |
|
2020-06-01 |
| Muscle Mass and Strength as Predictors of Time to Discharge in Patients With COVID-19 |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Sao Paulo |
|
Brazil |
2020-05-23 |
2022-05-23 |
31303720.7.0000.0068, NCT04406233 |
Phase Not Applicable |
Recruiting |
1 |
24 Months |
176 |
Bruno Gualano, Phd |
2020-06-01 |
| Prospective, observational study on cytokine removal effect of continuous hemodiafiltration in COVID-19 |
Coronavirus disease 19 infection |
continuous hemodiafiltration alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Juntendo University |
|
Japan |
2020-05-18 |
|
UMIN000040563 |
Phase Not Applicable |
Recruiting |
1 |
|
20 |
Junichiro Nakata |
2020-06-01 |
| Co-SURVIVORS: COVID-19: Respiratory and Sleep Follow-up |
Coronavirus disease 19 infection, Post traumatic stress disorder, Sleep disorder |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital, Grenoble |
|
France |
2020-06-05 |
2026-03-05 |
38RC20.157, Co-SURVIVORS, NCT04406324 |
Phase Not Applicable |
Not yet recruiting |
4 |
69 Months |
400 |
Anne-Laure Mounayar, MD, Bruno Chenuel, MD, Pr, Carole Planes, MD, Pr, Genevieve Derumeaux, MD, Pr, Jean-Louis Pepin, MD, Pr, PhD, Marie Destors, MD, Nicolas Terzi, MD, Pr, Renaud Tamisier, MD, PhD, MBA, Renaud Tamisier, MD, Pr, PhD, Sam Bayat, MD, Pr, PhD |
2020-06-01 |
| Microvascular Flow and Reactivity in Patients Presenting in the Acute Phase of COVID-19 |
Cardiovascular disease, Coronavirus disease 19 infection |
skin laser Doppler perfusion monitoring alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Instituto Nacional de Cardiologia |
|
Brazil |
2020-05-15 |
2020-11-30 |
#CAAE 31237220.1.0000.5272, NCT04406545 |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
25 |
Eduardo Tibirica, Eduardo Tibirica, MD, PhD |
2020-06-02 |
| A Study to Assess the Feasibility of Screening for SARS-CoV-2 Among Healthy Workers |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Miltenyi Biotec B.V. & Co. KG |
|
Germany |
2020-04-22 |
2021-01-31 |
M-2020-360, NCT04405466 |
Phase Not Applicable |
Recruiting |
1 |
9 Months |
500 |
Barbara von Ingersleben, Dr., Sandra Karitzky, Dr. |
2020-06-01 |
| REMDACTA: A Study to Evaluate the Efficacy and Safety of Remdesivir Plus Tocilizumab Compared With Remdesivir Plus Placebo in Hospitalized Participants With Severe COVID-19 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
standard of care alone, remdesivir plus tocilizumab (intravenous), Roche/Chugai |
COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, IL-6 receptor antagonist, IL-6 receptor modulator, RNA polymerase modulator |
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Genentech Inc, Roche Holding AG |
Gilead Sciences Inc |
Canada, Europe, US |
2020-05-31 |
2020-07-31 |
2020-002275-34, NCT04409262, REMDACTA, WA42511 |
Phase 3 Clinical |
Not yet recruiting |
2 |
2 Months |
450 |
Clinical Trials |
2020-06-02 |
| ET-COVID-19: Endovascular Thrombectomy in COVID-19 Infected Patients |
Coronavirus disease 19 infection, Ischemic stroke |
mechanical thrombectomy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital, Montpellier |
|
France |
2020-04-01 |
2020-06-30 |
ET-COVID-19, NCT04406090, RECHMPL20_0322 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
50 |
Federico Cagnazzo, MD, Federico Cagnazzo, MD PhD, Vincent COSTALAT, PhD, MD, MSc |
2020-06-01 |
| QUARCOPSY: Consequences of the QUARANTINE Relating to the Covid-19 Epidemic on the Mental Health of the Patients Followed in Psychiatry |
Anxiety disorder, Coronavirus disease 19 infection, Mood disorder, Personality disorder, Post traumatic stress disorder, Psychotic disorder, Somatoform disorder |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Regional Universitaire de Lille |
|
|
2020-05-31 |
2021-05-31 |
2020-A01186-33, 2020_39, NCT04405362, QUARCOPSY |
Phase Not Applicable |
Not yet recruiting |
0 |
12 Months |
753 |
Arnaud Leroy, MD |
2020-06-01 |
| The Impact of quarantine and social distancing on mental health in the context of the Covid-19 pandemic |
Coronavirus disease 19 infection, Psychiatric disorder |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Eberhard Karls Universität Tübingen |
|
Germany |
2020-04-08 |
|
A2.5.4-120_kr, DRKS00021791 |
Phase Not Applicable |
No longer recruiting |
1 |
|
|
Sebastian Wolf |
2020-06-01 |
| Prevention of Coronavirus Disease (COVID-19) Outbreaks With Nitazoxanide |
Coronavirus disease 19 infection |
nitazoxanide alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Materno-Perinatal Hospital of the State of Mexico |
Laboratorios Liomont Sa De Cv |
Mexico |
2020-05-21 |
2020-12-31 |
2020-04-682, NCT04406246 |
Phase 4 Clinical |
Recruiting |
1 |
7 Months |
150 |
Hugo Mendieta Zeron, PhD, Hugo Mendieta Zerón, MD., PhD., José Meneses Calderón, MD, José Meneses Calderón, MD., Marlen Santamaría Benhumea, PhD., Nancy Santamaría Benhumea, Bachelor in Law |
2020-06-01 |
| PACTT: Hydroxychloroquine, Azithromycin in the Treatment of Covid-19 |
Coronavirus disease 19 infection, Viral pneumonia |
standard of care alone, azithromycin plus hydroxychloroquine |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Farhat Hached University Hospital |
|
Tunisia |
2020-05-31 |
2021-03-31 |
NCT04405921, PACTT, PACTT |
Phase 3 Clinical |
Not yet recruiting |
1 |
10 Months |
200 |
Amel Letaief, Amel Letaief, Professor |
2020-06-01 |
| Covid-HUS: Clinical, Biological and Genetic Prognostic Factors for SARS-CoV-2 Infection in Patients Hospitalized in Strasbourg |
Coronavirus disease 19 infection |
|
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hopitaux Universitaires de Strasbourg |
|
France |
2020-03-27 |
2022-03-31 |
7760, Covid-HUS, NCT04405726 |
Phase Not Applicable |
Recruiting |
1 |
24 Months |
500 |
Aurélie VELAY, MD, Eric SOULIER, InG, Floriane GALLAIS, MD, François DANION, MD, Héloïse DELAGREVERIE, MD, Ilies BENOTMANE, MD, Morgane SOLIS, MD, Nicolas LEFEBVRE, MD, Nicolas MEYER, MD, PhD, Samira FAFI-KREMER, PharmD, PhD, Saïd CHAYER, PhD, HDR, Yves HANSMANN, MD, Yvon RUCH, MD |
2020-06-02 |
| A global, multicenter, randomized, double-blinded, placebo-controlled trial to assess the efficacy, safety and tolerability of LYT-100 in non-critical COVID-19 patients with respiratory complications |
Coronavirus disease 19 infection, Fibrosis, Inflammatory disease, Respiratory disease |
deupirfenidone alone |
PDGF receptor antagonist, TGF beta receptor antagonist, p38 MAP kinase inhibitor |
|
PureTech Health Plc |
|
|
2020-09-23 |
|
|
Phase Not Applicable |
Planned |
0 |
|
150 |
|
2020-05-29 |
| CAPANCOVID-19: Reorganization of the Healthcare System During COVID-19 Pandemic: Impact on Management of Patients With Exocrine Pancreatic Cancer |
Adenocarcinoma, Coronavirus disease 19 infection, Pancreas tumor |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire de Reims |
|
France |
2020-04-01 |
2022-04-30 |
CAPANCOVID-19, NCT04406571, PO20042 |
Phase Not Applicable |
Recruiting |
1 |
25 Months |
700 |
Olivier BOUCHE |
2020-06-01 |
| Investigating the efficacy of Provita Capsule in controlling the symptoms of patients with COVID-19 |
Coronavirus disease 19 infection, Cough, Dyspnea, Fever |
Provita alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Bagheiat-allah University of Medical Sciences, TAK GENE ZIST |
Baqiyatallah University of Medical Sciences |
Iran |
2020-05-14 |
|
IR.BMSU.REC.1399.124, IRCT20080901001165N60 |
Phase 3 Clinical |
Recruiting |
1 |
|
30 |
Gholamhosein Alishiri, Maryam Tajabadi, Mostafa Ghanei, Parisa Kianpour, Seyed Hasan Saadat, Yunes Panahi |
2020-06-01 |
| Dose-Confirmation Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1273 COVID-19 Vaccine in Adults Aged >/= 18 Years |
Coronavirus disease 19 infection |
mRNA-1273 alone |
COVID19 Spike glycoprotein modulator |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
ModeRNA Therapeutics |
Biomedical Advanced Research and Development Authority (BARDA), US Department of Health and Human Services |
US |
2020-05-25 |
2021-08-31 |
75A50120C00034, MRNA-1273-P201, NCT04405076 |
Phase 2a Clinical |
Recruiting |
10 |
15 Months |
600 |
Moderna Clinical Trials |
2020-06-01 |
| A Safety, Tolerability and Efficacy of EIDD-2801 to Eliminate Infectious Virus Detection in Persons With COVID-19 |
Coronavirus disease 19 infection |
EIDD-2801, Drug Innovation Ventures/Georgia State University/Emory University alone |
RNA polymerase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ridgeback Biotherapeutics LP |
|
US |
2020-05-26 |
2020-07-13 |
EIDD-2801-2003, NCT04405570 |
Phase 2a Clinical |
Not yet recruiting |
1 |
1 Month |
44 |
Laura Szewczyk, Susan Pedersen, William Fischer |
2020-06-01 |
| IMPACT SMI-COVID-19 Survey: Investigating the impact of COVID-19 and its response, on people with severe mental illness in South Asia |
Bipolar disorder, Coronavirus disease 19 infection, Depression, Schizoaffective disorder, Schizophrenia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of York |
National Institute for Health Research (NIHR) |
Bangladesh, Pakistan, India |
2020-04-10 |
2022-02-01 |
IMPACT SMI-COVID-19 Survey, ISRCTN15571919, NIL KNOWN |
Phase Not Applicable |
Recruiting |
6 |
21 Months |
2000 |
Dr Zavala |
2020-06-01 |
| Multi-site audit of COVID-19 airway interventions |
Coronavirus disease 19 infection |
airway intervention alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
St Vincents Hospital Sydney Ltd |
|
Australia |
2020-04-30 |
2021-03-27 |
ACTRN12620000617965 |
Phase Not Applicable |
Recruiting |
1 |
10 Months |
100 |
Dr Erez Ben-Menachem |
2020-06-01 |
| In a simulation environment, is there a difference in time taken for consultant anesthetists to perform spinal anaesthesia as compared to general anesthesia on women, with suspected or confirmed COVID-19, who require emergency cesarean delivery? |
Coronavirus disease 19 infection |
general anesthesia simulation alone, spinal anesthesia simulation alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Mackay Base Hospital |
|
Australia |
2020-05-20 |
2020-06-01 |
ACTRN12620000579998, U1111-1251-9551 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
10 |
Dr Marcelo Epsztein Kanczuk |
2020-06-01 |
| TROCAR: Tocilizumab for treatment Of COVID-19 in intensive care patients |
Coronavirus disease 19 infection |
tocilizumab (intravenous), Roche/Chugai alone |
IL-6 receptor antagonist, IL-6 receptor modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Queensland Institute of Medical Research |
|
Australia |
2020-05-26 |
|
ACTRN12620000580976, TROCAR |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
4 |
|
150 |
A/Prof Bridget Barber |
2020-06-01 |
| Post-Intensive Care Nutrition Status in Patients with COVID-19 |
Coronavirus disease 19 infection, Malnutrition |
|
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Australian and New Zealand Intensive Care Research Centre |
|
Australia |
2020-05-29 |
|
ACTRN12620000602921 |
Phase Not Applicable |
Not yet recruiting |
9 |
|
200 |
Dr Emma Ridley |
2020-06-01 |
| Covid-19 Biobank of clinical samples and data for use in research to help understand the immune characteristics of people who are diagnosed with COVID19 |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Alfred Health |
Lord Mayor's Charitable Foundation |
Australia |
2020-04-16 |
|
ACTRN12620000609954, U1111-1252-1632 |
Phase Not Applicable |
Recruiting |
6 |
|
250 |
Dr James McMahon, Ms Janine Roney |
2020-06-01 |
| A clinical study performance of the SARS-CoV-2 ELISA Kit was compared with a molecular diagnosis (PCR) using serum samples |
Coronavirus disease 19 infection |
SARS-CoV-2 ELISA Kit alone |
|
|
Enzo Biochem Inc |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
150 |
|
2020-06-01 |
| The MEND Trial: The MEND (MEseNchymal coviD-19) Trial: a pilot study to investigate early efficacy of mesenchymal stem cells in adults with COVID-19 |
Coronavirus disease 19 infection |
mesenchymoangioblast-derived mesenchymal stem cell therapy (Cymerus, critical limb ischemia/graft versus host disease/asthma/diabetic foot ulcer), Cynata/FUJIFILM alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cynata Therapeutics Ltd |
Cerebral Palsy Alliance Research Foundation |
Australia |
2020-06-01 |
|
ACTRN12620000612910, The MEND Trial |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
2 |
|
24 |
A/Prof Vineet Nayyar, Dr Kilian Kelly, Dr Madison Paton |
2020-06-01 |
| Validation of COVID-19 Tests |
Coronavirus disease 19 infection |
RAPG-COV-019 test kit membrane-based immunoassay alone, quantitative IgG test alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Richmond Pharmacology Limited |
|
UK |
2020-03-16 |
2020-08-31 |
C20010, NCT04404062 |
Phase Not Applicable |
No longer recruiting |
1 |
5 Months |
500 |
Jorg Taubel, MD |
2020-06-02 |
| COVIT-D: Increased Risk of Severe Coronavirus Disease 2019 Infection in Patients With Vitamin D Deficiency |
Coronavirus disease 19 infection, Vitamin D deficiency |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Clinico San Carlos |
|
Spain |
2020-04-17 |
2020-07-01 |
20/428-E_COVID, COVIT-D, NCT04403932 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
500 |
Fernando Macaya, Francisco J Martín, MD PhD |
2020-06-02 |
| A proof-of-concept clinical study to assess whether the Prototype Polygenic Risk Score would differentiate COVID-19 patients who required hospitalization from those who did not require hospitalization |
Coronavirus disease 19 infection |
Prototype Polygenic Risk Score alone |
|
|
Genetic Technologies Ltd |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
1500 |
|
2020-05-29 |
| COVID-PSL: Observational Study in Diagnosed Patients COVID-19, Supported on an Outpatient Basis |
Coronavirus disease 19 infection |
telephone consultation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre de Recherches et d'Etude sur la Pathologie Tropicale et le Sida |
|
France |
2020-06-15 |
2020-08-15 |
COVID-PSL, CREPATS 011, NCT04402905 |
Phase Not Applicable |
Not yet recruiting |
1 |
2 Months |
450 |
Christine Katlama, MD, Yasmine Dudoit |
2020-06-02 |
| IONIC: IMU-838 and Oseltamivir in treatment of Novel Coronavirus (COVID-19) |
Coronavirus disease 19 infection |
standard care alone, oseltamivir plus vidofludimus |
Dihydroorotate dehydrogenase inhibitor, Exo-alpha sialidase inhibitor, IL-17 antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospitals Coventry & Warwickshire NHS Trust |
|
UK |
2020-05-15 |
|
2020-001805-21, IONIC, RA486120 |
Phase 2 Clinical |
Recruiting |
1 |
|
120 |
Kavi Sharma |
2020-06-02 |
| Investigating the efficacy and safety of Niwasha mouthwash in controlling the symptoms of patients with COVID-19 |
Coronavirus disease 19 infection |
Niwasha mouthwash alone, routine treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Baqiyatallah University of Medical Sciences |
|
Iran |
2020-05-25 |
|
IRCT20080901001165N59, ir.bmsu.rec.1399.021 |
Phase 3 Clinical |
Recruiting |
1 |
|
80 |
Ali Ghazivini, Dr. Ghahreman, Mohammad Rezapour, Parisa Kianpour, Yunes Panahi |
2020-06-02 |
| Investigating the efficacy and safety of Plasmapheresis in patients with Moderate to severe COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
Plasmapheresis alone, Routine treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Bagheiat-allah University of Medical Sciences |
|
Iran |
2020-04-29 |
|
IR.BMSU.REC.1399.119, IRCT20080901001165N58 |
Phase Not Applicable |
Recruiting |
1 |
|
100 |
Behzad Einollahi, Gholamhosein Alishiri, Mohammad Rezapour, Parisa Kianpour, Yunes Panahi |
2020-05-29 |
| IgG/IgM Antibody Test in Patients Who Have Tested Negative or Positive for COVID-19 With Nasopharyngeal PCR Testing |
Coronavirus disease 19 infection |
SARS-Cov2 virus IgG/IgM Clungene rapid test cassette alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sharp HealthCare |
|
US |
2020-05-05 |
2020-12-01 |
2005801, IGG/IGM COVID19, NCT04402814 |
Phase Not Applicable |
Recruiting |
3 |
6 Months |
60 |
Divina Fanning, RN, Fadi Haddad, MD, Kathryn Miller |
2020-05-29 |
| Pembrolizumab (CinnaGen Co, Iran) in COVID-19 |
Coronavirus disease 19 infection |
Standard of care alone, pembrolizumab, CinnaGen alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
CinnaGen Co |
|
Iran |
2020-06-06 |
|
IR.SBMU.NRITLD.REC.1399.117, IRCT20150303021315N19 |
Phase 2 Clinical |
Not yet recruiting |
2 |
|
62 |
Alireza Rezvani, Nasim Anjidani, Payam Tabarsi |
2020-05-29 |
| Endotoxin and circulating bacteriome in severe COVID-19 patients |
Coronavirus disease 19 infection, Sepsis, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Chulalongkorn University |
|
Thailand |
2020-03-13 |
|
TCTR20200527001 |
Phase Not Applicable |
Completed |
1 |
|
19 |
Nattachai Srisawat |
2020-06-02 |
| Egyptian Doctors Stresses, Knowledge and Attitude During COVID-19 Pandemic |
Acute stress disorder, Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Ain Shams University |
|
Egypt |
2020-05-31 |
2020-06-30 |
EGYPTIAN DOCTORS IN COVID-19, NCT04403581 |
Phase Not Applicable |
Not yet recruiting |
1 |
1 Month |
384 |
Riham H Raafat, MD |
2020-05-29 |
| Impact of COVID-19 on Personal Protection Among Dentist in Egypt |
Coronavirus disease 19 infection |
online survey alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Fayoum University, EG |
|
Egypt |
2020-05-20 |
2020-06-15 |
NCT04403828, PPE IN COVID-19 |
Phase Not Applicable |
Recruiting |
1 |
|
300 |
Aliaa I Mahroun, PhD, Aliaa I Mahrous, PhD, Alshaimaa A Shabaan, PhD, Alshaimaa Ahmed shabaan |
2020-06-02 |
| Convalescent Plasma Therapy in Severe COVID-19 Infection |
Coronavirus disease 19 infection, Respiratory distress syndrome |
antibiotic therapy alone, fluid therapy alone, steroid therapy alone, Variable regimens including apheretic convalescent plasma , enoxaparin sodium , favipiravir , lopinavir + ritonavir , oxygen , remdesivir |
COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, HIV protease inhibitor, Low molecular weight heparin, RNA polymerase inhibitor, RNA polymerase modulator |
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Bangabandhu Sheikh Mujib Medical University |
Dhaka medical college |
Bangladesh |
2020-05-20 |
2020-10-30 |
BSMMU/2020/6104, NCT04403477 |
Phase 2 Clinical |
Recruiting |
1 |
5 Months |
20 |
Fazle R Chowdhury, FCPS, PhD, Fazle R Chowdhury, FCPS, PhD, Fazle Rabbi Chowdhury, Mohammad S Rahman, MPhil,FCPS, Mohammad S Rahman, MPhil, FCPS, Sayedur Rahman, MPhil, FCPS |
2020-05-28 |
| Covid-Immun: The role of immune-reactions in patients with COVID-19 |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Heidelberg |
|
Germany |
2020-03-18 |
|
Covid-Immun, DRKS00021810, S-148/2020 |
Phase Not Applicable |
Recruiting |
1 |
|
1000 |
Uta Merle |
2020-05-29 |
| A clinical study of convalescent plasma therapy in patients hospitalized with COVID-19 |
Coronavirus disease 19 infection |
convalescent plasma therapy alone |
|
|
Mount Sinai Hospital |
|
Canada |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
39 |
|
2020-06-01 |
| Characterizing SARS-CoV-2-specific Immunity in Individuals Who Have Recovered From COVID-19 |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
HIV Vaccine Trials Network |
HIV Prevention Trials Network, National Institute of Allergy and Infectious Diseases |
US, Peru |
2020-05-13 |
2021-08-31 |
5UM1AI068614-14, HVTN 405/HPTN 1901, NCT04403880 |
Phase Not Applicable |
Recruiting |
27 |
15 Months |
400 |
CRS Coodinator, CRS Coordinator, CRS Coorindator, CRS Leader, Clinical Trial Manager, E CRS Coordinator, Fernando Roman, Larry Corey, Protocol Team Leader, Shelly Karuna |
2020-05-30 |
| SOCRATES: Somerset and South Essex Coronavirus Antigen Testing |
Coronavirus disease 19 infection |
PCL COVID-19 Ag rapid FIA test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Somerset NHS Foundation Trust |
|
UK |
2020-06-30 |
2021-08-31 |
IRAS283137, NCT04403906, SOCRATES |
Phase Not Applicable |
Not yet recruiting |
1 |
14 Months |
200 |
Caitlin Morgan, MBBS, Justin Pepperell, MD |
2020-05-28 |
| A clinical, double-blind, randomized study to assess the effects and safety of Ivermectin in patients with Severe Acute Respiratory Syndrome during the Covid-19 pandemic |
Coronavirus disease 19 infection, Respiratory distress syndrome |
ivermectin alone, Variable regimens including amoxicillin/clavulanate , azithromycin , oseltamivir |
Chloride channel modulator, Exo-alpha sialidase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Faculdade de Medicina de São José do Rio Preto, Hospital de Base de São José do Rio Preto |
|
Brazil |
2020-05-01 |
|
30899920.5.1001.5415, 4.031.618, RBR-7hzhwd, U1111-1250-6724 |
Phase 2b Clinical |
Recruiting |
1 |
|
566 |
Suzana Margareth Lobo |
2020-06-02 |
| Convalescent plasma to limit COVID-19 associated complications |
Coronavirus disease 19 infection |
Convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Yale University |
Albert Einstein College of Medicine, NYU Langone Health |
|
2020-05-31 |
2023-01-31 |
2000028181, NCT04404634 |
Phase 2 Clinical |
Not yet recruiting |
0 |
32 Months |
300 |
Alessandro Santin, MD, Mahalia Desruisseaux, MD |
2020-05-29 |
| Comparative assessment of the efficacy and safety of addon treatment with 'Sofosbuvir-Daclatasvir', 'Lithium',and 'Trifluoprazine' to 'standard of care' in three groups of patients with COVID-19 |
Coronavirus disease 19 infection |
hydroxychloroquine alone, Variable regimens including Sofosbuvir + Daclatasvir , hydroxychloroquine , lithium , trifluoperazine , trihexyphenidyl |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kermanshah University of Medical Sciences |
|
Iran |
2020-04-08 |
|
IR.KUMS.REC.1399.063, IRCT20130812014333N147 |
Phase 3 Clinical |
Recruiting |
1 |
|
80 |
Dr. Babak Sayad, Dr. Reza Khodarahmi, Feizollah Foroughi, habibolah khzaei |
2020-05-28 |
| DORNASESARS2: Dornase Alfa for ARDS in Patients With SARS-CoV-2 |
Coronavirus disease 19 infection, Lung injury, Respiratory distress syndrome, Respiratory failure |
dornase alfa alone, standard of care alone |
Deoxyribonuclease I stimulator, Deoxyribonuclease stimulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Missouri |
|
US |
2020-05-30 |
2022-05-31 |
2022206, DORNASESARS2, NCT04402970 |
Phase 3 Clinical |
Not yet recruiting |
1 |
24 Months |
20 |
Mohammed Alnijoumi, MD, Zachary M Holliday, MD |
2020-05-28 |
| S3-study: Sero-surveillance SARS-CoV-2 |
Coronavirus disease 19 infection |
Serologic surveillance alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Amsterdam UMC |
|
Netherlands |
2020-03-23 |
2020-12-31 |
NL8645, S3-study |
Phase Not Applicable |
Recruiting |
1 |
9 Months |
800 |
Jonne Sikkens |
2020-05-28 |
| COV-PLAS: A randomized, double blinded clinical trial of convalescent plasma compared to standard plasma for treatment of hospitalized non-ICU patients with COVID-19 infections |
Coronavirus disease 19 infection |
convalescent thawed fresh frozen plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Leiden University Medical Center |
|
Netherlands |
2020-05-31 |
2021-05-01 |
COV-PLAS, NL8633 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
11 Months |
430 |
Jaap Jan Zwaginga |
2020-05-28 |
| Ivermectin and Doxycycine in COVID-19 Treatment |
Coronavirus disease 19 infection |
doxycycline hyclate plus ivermectin (Iverzine) |
|
|
Tanta University |
|
Egypt |
2020-06-01 |
2030-12-03 |
NCT04403555, TANTA COMBO COVID TREATMENT |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
126 Months |
40 |
Sherief Abd-Elsalam, ass. prof., sherief Abd-Elsalam, Ass. Prof. |
2020-05-28 |
| The safety and efficacy of STC-3141 in patient with COVID-19 Acute Respiratory Distress Syndrome |
Adult respiratory distress syndrome, Coronavirus disease 19 infection |
STC-3141 alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Grand Medical Pty Ltd |
|
Australia |
2020-05-29 |
|
ACTRN12620000588998 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
160 |
Dr Marcel Tanudji, Prof Anders Aneman |
2020-05-28 |
| Familial Mediterranean Fever and Behcet: Analysis Before and After COVID-19 Pandemic |
Behcets disease, Coronavirus disease 19 infection, Familial mediterranean fever |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Istanbul University |
|
Turkey |
2020-04-01 |
2020-06-15 |
10840098-604.01.01-E.14697, NCT04403438 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
45 |
Nejla Uzun, MSc, Pt |
2020-05-28 |
| CoVEX: Different Susceptibility to SARS CoV-2 Infection Among Health Care Workers Highly Exposed to COVID-19 |
Coronavirus disease 19 infection |
Flow cytometry alone, PCR test alone, RT-PCR test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Asociacion para el Estudio de las Enfermedades Infecciosas |
|
Spain |
2020-06-01 |
2020-09-30 |
CoVEX, EC, EC 162/20, NCT04402827 |
Phase Not Applicable |
Recruiting |
1 |
4 Months |
60 |
Alejandro Vallejo, MD, PhD, Amaranta McGee, MD, Ana Moreno, MD, Carmen Quereda, MD, Elisabeth Sanchez, MD, Jose L Casado, MD, PhD, Jose L Casado, Md, PhD, Pilar Vizcarra, MD |
2020-06-01 |
| Convalescent Plasma treatment trial in COVID 19 patients |
Coronavirus disease 19 infection |
Convalescent Plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Wockhardt Ltd |
|
India |
2020-06-01 |
|
CTRI/2020/05/025299, WH-CP-02-21 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
20 |
Dr AjayKumar R Yadav, Dr Ashima Bhatia, Dr Behram Shawak Pardiwalla |
2020-06-02 |
| Survey of Mouth-dissolving Turmeric Lozenges in Healthcare Workers |
Coronavirus disease 19 infection |
Trumgel alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Gelnova Laboratories (India) Pvt Ltd |
|
India |
2020-05-26 |
|
CTRI/2020/05/025317 |
Phase 4 Clinical |
Not yet recruiting |
1 |
|
300 |
DR MANJUSHA RAJARSHI, Dr Niharika Gill |
2020-06-02 |
| TRANSCOVID: Study of Viral Load and Maternal-fetal Serology in the Interpretation of the Vertical Transmission of SARS Cov-2 (COVID-19) During Pregnancy |
Coronavirus disease 19 infection |
nasopharyngeal aspiration alone, nasopharyngeal swab sampling alone, placenta swab sampling alone, serology alone, vaginal swab sampling alone |
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital of Besancon |
|
France |
2020-05-17 |
2020-12-31 |
2020/500, NCT04402918, TRANSCOVID |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
160 |
Benazet Louis, MOTTET Nicolas, Dr |
2020-05-29 |
| LICCI: Trial of antihypertensive losartan for additional benefit in treating COVID 19 infection. |
Coronavirus disease 19 infection |
losartan alone, standard of care alone |
Angiotensin II AT-1 receptor antagonist, Angiotensin II receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sanjay Gandhi Postgraduate Institute of Medical Sciences |
|
India |
2020-06-01 |
|
CTRI/2020/05/025319, LICCI |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
186 |
Dr Able Lawrence |
2020-06-02 |
| Etiology of Lymphopenia in Covid-19 Infection |
Coronavirus disease 19 infection, Lymphocytopenia |
blood sampling alone, bone marrow aspiration cytology alone |
|
|
Cairo University |
|
Egypt |
2020-06-30 |
2021-12-31 |
201920008.2, NCT04404608 |
Phase Not Applicable |
Not yet recruiting |
1 |
18 Months |
90 |
Dr Medhat Khafagy |
2020-05-29 |
| YONAC: Effect of Yoga & Naturopathy in patients with COVID-19 |
Coronavirus disease 19 infection |
Yoga & Naturopathy immune boostinng and stress management protocol alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Government Yoga And Naturopathy Medical College |
Indian Naturopathy And Yoga Graduates Medical Associatio |
India |
2020-05-22 |
|
CTRI/2020/05/025320, YONAC |
Phase 3 Clinical |
Recruiting |
4 |
|
658 |
Manavalan Narayanaswamy |
2020-06-02 |
| Comparison of the ID NOW and Accula Point-of-Care Assays for Detection of COVID-19 |
Coronavirus disease 19 infection |
Accula (Mesa Biotech) alone, ID Now (Abbott) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ascension South East Michigan |
|
US |
2020-05-10 |
2021-05-09 |
1599159, NCT04403035 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
100 |
Leonard B Johnson, MD, Leonard B. Johnson, MD, Melphine Harriott, PhD |
2020-05-29 |
| The Hope Coalition - 1: Hydroxychloroquine and Lopinavir + Ritonavir to Improve the Health of People With COVID-19 |
Coronavirus disease 19 infection, Respiratory disease |
hydroxychloroquine alone, lopinavir + ritonavir alone, hydroxychloroquine plus lopinavir + ritonavir |
HIV protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cardresearch - Cardiologia Assistencial e de Pesquisa LTDA |
Cytel Inc |
Brazil |
2020-05-28 |
2020-11-28 |
COVID19-AMB-BRASIL, NCT04403100, The Hope Coalition - 1 |
Phase 3 Clinical |
Not yet recruiting |
4 |
6 Months |
1968 |
Daniela Silva, MD, PhD, Eduardo Silva, MD, PhD, Gilmar Reis, MD, PhD, Gilmar Reis, MD,PhD, Izabel Silva, SC, Leonardo Savassi, MD, PhD, Rosemary Oliveira, SC |
2020-05-29 |
| PH-94B in the Treatment of Adjustment Disorder With Anxiety |
Adjustment disorder, Anxiety disorder, Coronavirus disease 19 infection |
PH-94B alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
VistaGen Therapeutics Inc |
|
US |
2020-11-30 |
2021-09-30 |
COVID19_IMPACT, NCT04404192, PH94B-CL-029 |
Phase 2a Clinical |
Not yet recruiting |
1 |
10 Months |
30 |
Ann Draine, Matt Turzilli, Michael Liebowitz, MD |
2020-05-29 |
| Tablet PINAK given as treatment to COVID positive patients |
Coronavirus disease 19 infection |
PINAK alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shree Bharadi Ayurvedic Pharamaceuticals |
|
India |
2020-05-31 |
|
CTRI/2020/05/025326 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
30 |
Dr Pandurang Pawar, Shreepad Bhat |
2020-06-02 |
| PedCan-COVID: Extraordinary Measures for Egyptian Children With Hemato-Oncological Disorders During COVID-19 Pandemic |
Coronavirus disease 19 infection, Hematological disease, Hematological neoplasm, Respiratory disease, Solid tumor |
chest x-ray alone, computed chest tomography alone, reverse transcription polymerase chain reaction test alone |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Ain Shams University |
|
Egypt |
2020-01-01 |
2021-06-01 |
FMASU P25A/ 2020, NCT04404244, PedCan-COVID |
Phase Not Applicable |
Recruiting |
1 |
17 Months |
100 |
Fatma Ebeid, Fatma Soliman E Ebeid |
2020-06-02 |
| To study some blood tests which would help predict severity and outcome in children with cancers having the novel corona virus infection |
Coronavirus disease 19 infection |
|
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) |
Christian Medical College, Vellore, India |
|
India |
2020-06-09 |
|
CTRI/2020/05/025327 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
60 |
Deepthi Boddu |
2020-06-02 |
| COLORIT: Colchicine Versus Ruxolitinib and Secukinumab In Open, Prospective, Randomized Trial |
Coronavirus disease 19 infection, Viral pneumonia |
colchicine alone, ruxolitinib alone, secukinumab alone |
IL-17 antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
MV Lomonosov Moscow State University |
|
Russian Federation |
2020-05-08 |
2020-08-23 |
COLORIT, MSU080520, NCT04403243 |
Phase 2 Clinical |
Recruiting |
1 |
3 Months |
70 |
Julia Begrambekova, Phd, Julia Leonovna Begrambekova, Phd, Yana Orlova, Professor |
2020-05-29 |
| TOCIBRAS: Safety and Efficacy of Tocilizumab in Moderate to Severe COVID-19 With Inflammatory Markers |
Coronavirus disease 19 infection |
Best supportive care alone, tocilizumab (intravenous), Roche/Chugai alone, tocilizumab (subcutaneous), Roche/Chugai alone |
IL-6 receptor antagonist, IL-6 receptor modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Beneficencia Portuguesa of Sao Paulo |
Brazilian Clinical Research Institute, Brazilian Research In Intensive Care Network, Hospital Alemao Oswaldo Cruz, Hospital do Coracao, Instituto de Educação e Pesquisa do Hospital Moinhos de Vento, Sociedade Beneficente Israelita Brasileira Hospital Albert Einsten, Sociedade Beneficiente De Senhoras Hospital Sirio Libanes |
Brazil |
2020-05-08 |
2020-08-31 |
NCT04403685, TOCIBRAS, TOCIBRAS |
Phase 3 Clinical |
Recruiting |
7 |
3 Months |
150 |
Alexandre Biasi Cavalcanti, MD, Danielle Leao Cordeiro de Farias, MD, Danielle Leão Cordeiro de Farias, MD, Flavia R Machado, Joao Prats, MD, Luciano Azevedo, Phillip Scheinberg, MD, Viviane C Veiga, MD, Viviane Veiga, MD |
2020-05-29 |
| The Acai Berry COVID-19 Anti-inflammation Trial |
Coronavirus disease 19 infection |
acai palm berry extract (Nature's Way) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The University Health Network |
University of Toronto |
Canada |
2020-05-31 |
2021-05-31 |
CTO3176, NCT04404218 |
Phase 2 Clinical |
Not yet recruiting |
2 |
12 Months |
480 |
Ana Andreazza, PhD, Hassan Ellaban, Michael Farkouh, MD, MSc |
2020-05-29 |
| TaCOVID: Tannin Specific Natural Extract for COVID-19 Infection |
Coronavirus disease 19 infection |
antibiotic therapy alone, antipyretics therapy alone, non-invasive ventilation alone, supplemental oxygen therapy alone, Variable regimens including ARBOX , azithromycin , hydroxychloroquine , lopinavir + ritonavir |
HIV protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Jose de San Martin Hospital de Clinicas |
SILVATEAM |
Argentina |
2020-06-01 |
2020-10-31 |
HCJSM-20-005, NCT04403646, TaCOVID |
Phase 2 Clinical |
Not yet recruiting |
1 |
5 Months |
140 |
Maria M Piskorz, MD, Maria Marta Piskorz, MD |
2020-05-28 |
| COVID PLASMA: Study to Assess the Safety and Efficacy of Convalescent Plasma on outcome of COVID-19 Associated Complications |
Coronavirus disease 19 infection |
convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Indraprastha Apollo Hospitals |
|
India |
2020-06-01 |
|
COVID PLASMA, CTRI/2020/05/025328, Protocol No. Covid 19, Version no 1.1 |
Phase 2 Clinical |
Not yet recruiting |
5 |
|
100 |
Dr D Suresh Kumar, Dr Rajesh Chawla, Dr Suneetha Narreddy, Dr Suresh Ramasubban, Dr Tushar Parmar |
2020-06-02 |
| CISCO-19: Cardiac Imaging in SARS-CoV-2 (COVID-19) |
Coronavirus disease 19 infection, Heart injury, Myocarditis, Pulmonary heart disease |
MRI alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
NHS Greater Glasgow and Clyde |
University of Glasgow |
UK |
2020-05-22 |
2021-08-31 |
CISCO-19, GN20ID164, NCT04403607 |
Phase Not Applicable |
Recruiting |
3 |
15 Months |
180 |
Colin Berry, MBChB/PhD, Douglas Grieve, MBChB/PhD, Hannah Bayes, MBChB/PhD, Kenneth Mangion, MBChB/PhD, Kevin Blyth, MBChB/PhD, Lynsey Gillespie, PhD |
2020-05-28 |
| Performance Evaluation of RealDetect COVID-19 RT-PCR Kit for the Detection of SARS-CoV-2 Virus |
Coronavirus disease 19 infection |
RealDetect COVID-19 RT-PCR kit alone |
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Bangladesh Medical Research Council (BMRC) |
|
Bangladesh |
2020-05-18 |
2020-07-24 |
30005052020, NCT04403672 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
120 |
Rosy Sultana, MBBS, MPhil, Zahid Hassan, MBBS, PhD |
2020-06-01 |
| SR4COVID: Protect and prevent onset of COVID like infections in Health Care Workers and High risk person |
Coronavirus disease 19 infection |
REIMMUGEN plus SUVED |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Health Solutions, India |
|
India |
2020-05-30 |
|
CTRI/2020/05/025334, SR4COVID |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
30 |
Shreepad Bhat, Sujata Vaidya |
2020-06-01 |
| The Clinical Difference Between the Nonfatal Patients and the Fatal Patients With Severe COVID-19 |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The First Affiliated Hospital of Guangzhou Medical College |
|
China |
2020-02-01 |
2020-06-20 |
NCT04403009, YLS2020(112) |
Phase Not Applicable |
Recruiting |
2 |
4 Months |
100 |
jianheng zhang, MD |
2020-05-28 |
| PRE-VENT: Study in Hospitalized Patients With Severe COVID-19 With or Without Cancer |
Coronavirus disease 19 infection |
pacritinib alone, standard of care alone |
CSF-1 antagonist, Cytochrome P450 reductase inhibitor, Flt3 tyrosine kinase inhibitor, IRAK-1 protein kinase inhibitor, Jak2 tyrosine kinase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
CTI BioPharma Corp |
|
US |
2020-05-22 |
2021-10-31 |
NCT04404361, PAC319, PRE-VENT |
Phase 3 Clinical |
Not yet recruiting |
1 |
17 Months |
358 |
John Mascarenhas |
2020-06-02 |
| A biomarker study to assess the correlation between LIGHT levels and disease severity and mortality in a COVID-19 acute respiratory distress syndrome (ARDS) |
Coronavirus disease 19 infection, Respiratory distress syndrome |
|
|
Healthy volunteers accepted |
Cerecor Inc, Myriad Genetics Inc |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
77 |
|
2020-05-28 |
| EpiCovCreil: Study of SARS-CoV2 Virus (COVID-19) Seroprevalence in the Population of Creil Air Force Base (BA110) |
Coronavirus disease 19 infection |
Anti-SARS-CoV2 serology test alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Direction Centrale du Service de Sante des Armees |
|
France |
2020-05-31 |
2021-02-28 |
2020-COVID19-22, EpiCovCreil, NCT04404270 |
Phase Not Applicable |
Not yet recruiting |
1 |
9 Months |
2500 |
Anaïs GROSSET-JANIN, MD, Sandrine DURON, MD, PhD |
2020-05-29 |
| SARS Cov-2 in Conjunctival Secretion |
Coronavirus disease 19 infection, Viral pneumonia |
rtPCR alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Università degli Studi dell'Insubria |
|
Italy |
2020-02-01 |
2020-05-20 |
72/2020, NCT04402853 |
Phase Not Applicable |
Completed |
1 |
3 Months |
100 |
Simone Donati, Professor |
2020-05-29 |
| SARS-CoV-2 Saliva |
Coronavirus disease 19 infection |
|
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Hospital Sungai Buloh |
Ministry of Health, Malaysia |
Malaysia |
2020-05-18 |
2020-08-17 |
NMRR-20-902-54894 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
12 |
Dr Denisa Khoo Fern Ying, Dr Kalaiarasu Peariasamy |
2020-05-29 |
| Rapid antigen detection for SARS-CoV-2 |
Coronavirus disease 19 infection |
rapid antigen detection test alone |
|
|
National Institutes of Health Malaysia |
Ministry of Health, Malaysia |
Malaysia |
2020-06-01 |
2022-02-28 |
54859, NMRR-20-944-54859 |
Phase Not Applicable |
Status not specified |
1 |
21 Months |
|
Dr Norazah binti Ahmad, Ms Jamaayah Bt Mohamed Zahidi @ Ahmad Bakri |
2020-05-29 |
| HCW-COVID |
Coronavirus disease 19 infection |
|
|
|
HOSPITAL RAJA PEREMPUAN ZAINAB II |
|
Malaysia |
2020-06-01 |
2021-06-01 |
55011, NMRR-20-952-55011 |
Phase Not Applicable |
Status not specified |
1 |
12 Months |
2000 |
Dr Diana Foo Hui Ping, Dr LEE HUEY CHUN |
2020-06-02 |
| Generation of immune Fab phage display library against a novel coronavirus (2019-nCoV) |
Coronavirus disease 19 infection |
|
|
|
Universiti Sains Malaysia |
|
Malaysia |
2020-02-20 |
2020-12-31 |
34314, NMRR-17-3569-34314 |
Phase Not Applicable |
Status not specified |
1 |
10 Months |
|
Dr Jeyanthi a/p Suppiah, Dr. Mohammad Ridhuan Bin Mohd Ali |
2020-05-29 |
| Detailed Organ System Analysis of Asymptomatic COVID19 patients using noninvasive mobile tool |
Coronavirus disease 19 infection |
Lyfas Mobile tool alone |
|
Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Acculi Labs |
|
India |
2020-06-05 |
|
CTRI/2020/05/025345 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Dr Pooja Sharma, Dr Sushila Kataria, Rishikesh Ranjan |
2020-05-29 |
| LSALT Peptide versus Placebo to Prevent ARDS and Other Organ Injuries in Patients Infected With SARS-CoV-2 (COVID-19) |
Blood clotting disorder, Coronavirus disease 19 infection, Liver injury, Lung inflammation, Myocardial disease, Nephritis, Renal injury, Respiratory distress syndrome |
Metablok alone, standard of care alone |
Dehydropeptidase-1 modulator |
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Arch Biopartners Inc |
|
Canada |
2020-07-01 |
2021-06-30 |
AB002, NCT04402957 |
Phase 2 Clinical |
Not yet recruiting |
1 |
12 Months |
60 |
Daniel A Muruve, MD, Richard Muruve |
2020-05-29 |
| Pulmozyme to Improve COVID-19 ARDS Outcomes |
Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure, Viral pneumonia |
dornase alfa alone, standard of care alone |
Deoxyribonuclease I stimulator, Deoxyribonuclease stimulator |
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Boston Children's Hospital |
Brigham & Women's Hospital |
US |
2020-05-25 |
2021-12-31 |
NCT04402944, P00035140 |
Phase 2 Clinical |
Not yet recruiting |
1 |
19 Months |
60 |
Benjamiin Raby, Robert Fowler |
2020-05-29 |
| A Clinical Trial to Assess the Safety and Efficacy of Convalescent Plasma in Severe COVID-19 patients |
Coronavirus disease 19 infection |
convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Government of Tamil Nadu |
|
India |
2020-06-01 |
|
CTRI/2020/05/025346, Form CT-06, No. CT/BP/07/2020 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
90 |
Dr Latha B, Dr S Anbuselvi Mattuvar Kuzhali, DrJAYANTHI RANGARAJAN |
2020-05-28 |
| Resistir: Th1/Th2/Th17/TREG and TLRs Activation/KIR for COVID-19 Prediction of Outcome |
Coronavirus disease 19 infection |
RT-PCR alone, flow cytometry alone, plasma sampling alone, polymerase chain reaction alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Asociacion para el Estudio de las Enfermedades Infecciosas |
Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal |
Spain |
2020-05-22 |
2020-09-30 |
EC128/20, NCT04403061, Resistir |
Phase Not Applicable |
Recruiting |
1 |
4 Months |
80 |
Alejandro Vallejo, MD, PhD, Ana Moreno, MD, PhD, Carmen Quereda, MD, PhD, Jose L Casado, Md, PhD, Jose M Del Rey, MD, PhD, Pilar Vizcarra, MD |
2020-05-29 |
| 'Increasing Physical Activity in Canadian Adults Who Have Been Affected by COVID-19 Social Distancing Restrictions: A Feasibility Trial of an Online Intervention' (COVID-19) |
Coronavirus disease 19 infection |
Digital Health Online Platform alone, baseline questionnaire alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Victoria |
|
Canada |
2020-05-20 |
2020-09-30 |
05-281983, NCT04400305 |
Phase Not Applicable |
Recruiting |
1 |
4 Months |
40 |
Ryan Rhodes, Sandy L Courtnall, Stina Grant |
2020-05-29 |
| Prospective, Natural History Study of Smoking, Immune Cell Profiles, Epigenetics and COVID-19 |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
National Institute Of Environmental Health Sciences |
National Institutes of Health Clinical Center |
US |
2020-06-04 |
2022-05-31 |
20-E-0108, 200108, NCT04403386 |
Phase Not Applicable |
Recruiting |
2 |
23 Months |
200 |
Nicole Edwards, Stavros Garantziotis, M.D. |
2020-06-02 |
| Study to assess safety and efficacy of Inj Sepsivac in patients of COVID-19 |
Coronavirus disease 19 infection |
Sepsivac alone, standard therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
RD Gardi Medical College |
|
India |
2020-05-31 |
|
CTRI/2020/05/025350 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
50 |
Dr Ashish Pathak |
2020-05-29 |
| QTW2020: COVID-19 Brief Advice and Chat-based Support for Smoking Cessation Via 'Quit to Win' Contest 2020 |
Coronavirus disease 19 infection, Nicotine dependence |
AWARD advice alone, COSH booklet alone, COVID-19 specific advice alone, COVID-related health warning leaflet alone, Personalized instant messaging alone, referral card alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The University of Hong Kong |
Hong Kong Council on Smoking and Health |
Hong Kong |
2020-06-13 |
2022-06-30 |
NCT04399967, QTW 2020, QTW2020 |
Phase Not Applicable |
Not yet recruiting |
1 |
24 Months |
842 |
Man Ping Kelvin Wang, PhD, Xue Weng, PhD |
2020-05-29 |
| FAITH: A Phase III study of Favipiravir and Umifenovir in hospitalized patients of moderate COVID-19 in India |
Coronavirus disease 19 infection |
standard supportive care alone, favipiravir plus umifenovir |
RNA polymerase inhibitor |
|
Glenmark Pharmaceuticals Ltd |
|
India |
|
|
FAITH |
Phase 3 Clinical |
Planned |
1 |
|
158 |
|
2020-06-01 |
| A Study of APL-9 in Adults With Mild to Moderate ARDS Due to COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure |
APL-9 alone, standard of care alone |
Complement C3 modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Apellis Pharmaceuticals Inc |
|
US |
2020-05-26 |
2020-11-30 |
APL9-COV-201, NCT04402060 |
Phase 1/Phase 2 Clinical |
Recruiting |
4 |
6 Months |
66 |
Apellis Clinical Trial Information Line |
2020-06-01 |
| CACOLAC: Citrulline Administration in the Hospital Patient in Intensive Care for COVID-19 Acute Respiratory Distress Syndrome |
Coronavirus disease 19 infection, Lung disease, Respiratory distress syndrome, Viral pneumonia |
L-citrulline alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Rennes University Hospital |
|
France |
2020-06-15 |
2021-07-15 |
2020-A01189-30, 35RC20_9815_CACOLAC, CACOLAC, CPP 1288 HPS1, NCT04404426 |
Phase Not Applicable |
Not yet recruiting |
5 |
13 Months |
100 |
Agathe Delbove, MD, Aurélien Frerou, MD, Erwan L'Her, MD, Florian Reizine, MD, Jean-Marc Tadié, MD, Pierre Asfar, MD |
2020-05-29 |
| IVERCOVID: Does ivermectin cure and/or prevent COVID-19? |
Coronavirus disease 19 infection |
|
|
|
Lagos State University Teaching Hospital |
|
Nigeria |
2020-04-23 |
2020-06-23 |
ISRCTN40302986, IVERCOVID |
Phase Not Applicable |
Recruiting |
2 |
2 Months |
|
Prof Babalola |
2020-05-29 |
| StudentCov: Psychological Impact of the Covid-19 Pandemic on Student Nurses |
Coronavirus disease 19 infection, Post traumatic stress disorder |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Central Hospital, Versailles |
|
France |
2020-05-12 |
2020-07-31 |
NCT04402229, P17/04_STUDENTCOV, StudentCov |
Phase Not Applicable |
Recruiting |
2 |
2 Months |
2000 |
Guillaume Decormeille, RN, MSc, Gwenaelle Jacq, RN, Jacq Gwenaelle, Stephane Legriel, MD, PhD |
2020-05-29 |
| Real-World Antiviral Therapy In COVID-19 |
Coronavirus disease 19 infection |
antiviral therapy alone |
|
|
Hospital Universiti Sains Malaysia |
|
Malaysia |
2020-05-20 |
2021-08-31 |
54911, NMRR-20-1006-54911 |
Phase 4 Clinical |
Not yet recruiting |
4 |
15 Months |
|
Dr Lee Yeong Yeh, SITI NORIZAN BINTI ABDUL RANI |
2020-05-29 |
| COVID-19 Seroprevalence in RRT patients |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Malaya Medical Centre |
|
Malaysia |
2020-06-01 |
2020-12-31 |
54927, NMRR-20-997-54927 |
Phase Not Applicable |
Not yet recruiting |
2 |
7 Months |
650 |
Dr Rosnawati Yahya, LIM SOO KUN |
2020-05-29 |
| Efficacy of AYUSH-64 (a polyherbal formulation) in COVID - 19 Cases |
Coronavirus disease 19 infection |
AYUSH-64 alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Central Council for Research in Ayurvedic Sciences |
|
India |
2020-05-31 |
|
CTRI/2020/05/025335 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
40 |
Dr N R Singh, Dr Vidula Gujjarwar |
2020-06-02 |
| Randomized Controlled Trial Of Resveretrol-Copper Or Sodium-Copper-Chlorophyllin Vs Standard Treatment In Mild Covid-19 infection |
Coronavirus disease 19 infection |
Resveratrol- Copper alone, antibacterial therapy alone, antibiotic therapy alone, antimicrobial therapy alone, antiviral therapy alone, sodium-copper-chlorophyllin alone, standard treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tata Memorial Centre |
|
India |
2020-06-01 |
|
CTRI/2020/05/025336 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
300 |
Indraneel Mittra, Vikram Gota |
2020-06-02 |
| Randomized Controlled Trial Of Resveretrol-Copper OR Sodium-Copper-Chlorophyllin Versus Standard Treatment In Severe Covid-19 |
Coronavirus disease 19 infection |
Resveratrol- Copper alone, antibacterial therapy alone, antibiotic therapy alone, antimicrobial therapy alone, antiviral therapy alone, sodium-copper-chlorophyllin alone, standard treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tata Memorial Centre |
|
India |
2020-06-01 |
|
CTRI/2020/05/025337 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
200 |
Indraneel Mittra, Vikram Gota |
2020-06-02 |
| Predictive Models for Intensive Care Admission and Death of COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), African Ancestry, European Ancestry |
Cliniques Saint-Pierre Ottignies |
|
Belgium |
2020-03-01 |
2021-01-01 |
0410508057, NCT04401228 |
Phase Not Applicable |
No longer recruiting |
1 |
10 Months |
60 |
Nicolas Parisi |
2020-05-29 |
| COLIDE: COVID-19: Laser Interferometry for Rapid Single Coronavirus Detection |
Coronavirus disease 19 infection |
laser interferometry test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Somerset NHS Foundation Trust |
Exeter University, University of Plymouth |
UK |
2020-06-30 |
2021-12-31 |
COLIDE, NCT04401644, RBA20203 |
Phase Not Applicable |
Not yet recruiting |
1 |
18 Months |
250 |
Flora Darch, Karen Tanner |
2020-05-29 |
| Evaluation of Efficacy and Safety of Ayurveda Intervention (Ayush -64) in the management of COVID-19 infection (Asymptomatic &Mild to Moderate symptoms |
Coronavirus disease 19 infection |
Ayush 64 alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Central Council for Research in Ayurvedic Sciences |
|
India |
2020-06-02 |
|
CTRI/2020/05/025338 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
40 |
Dr BabitaYadav, Dr Manoj Shamkuwar, Dr Shivshankar Rajput |
2020-06-02 |
| Prevalence and Severity of Venous Thromboembolism in a General Population During the COVID-19 Pandemic |
Coronavirus disease 19 infection, Deep vein thrombosis, Lung embolism |
CT pulmonary angiogram alone, ultrasound alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital, Linkoeping |
|
Sweden |
2020-06-01 |
2020-06-30 |
NCT04400877, SE2020-02701 |
Phase Not Applicable |
Not yet recruiting |
1 |
1 Month |
12000 |
Daniel Wilhelms, Daniel Wilhelms, PhD, Jens Wretborn, MD, Joakim Henricson, PhD, Matthias Jörg, MD, Patrik Benjaminsson Nyberg, PhD |
2020-05-29 |
| Treatment and economical problems faced due to non COVID patients admitted in severe acute respiratory illness (SARI) ICU based on SARI criteria |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kasturba Medical College and Hospital |
|
India |
2020-06-02 |
|
COVID_IMPACT, CTRI/2020/05/025339 |
Phase Not Applicable |
Not yet recruiting |
2 |
|
500 |
Dr Sumalatha A, Dr Sunil R |
2020-06-02 |
| Controlled and randomized trial to assess the safety and efficacy of hydroxychloroquine chemoprophylaxis in SARS CoV2 infection in hospital healthcare personnel (Sanitarios sin COVID-19) |
Coronavirus disease 19 infection, SARS coronavirus infection |
Hydroxychloroquine alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Fundacion Instituto de Investigacion Marques de Valdecilla, IDIVAL |
|
Spain |
2020-05-15 |
|
2020-001704-42, SANsinCOVID |
Phase 4 Clinical |
No longer recruiting |
1 |
|
450 |
Mar García Sáiz |
2020-05-29 |
| Clinical trial of ShatPlus in SARS-CoV-2 Infection |
Coronavirus disease 19 infection |
ShatPlus alone, Standard treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
BVG Life Sciences Ltd |
|
India |
2020-06-01 |
|
CTRI/2020/05/025340, PROTOCOL NO- MHC/CT/20-21/001 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
|
60 |
Dr Patsute Sudhir Dadaram, Dr Pawan Kumar Singh |
2020-06-02 |
| Study on Safety and Efficacy of Favipiravir (Favipira) for COVID-19 Patient in Selected Hospitals of Bangladesh |
Coronavirus disease 19 infection |
favipiravir alone, standard treatment alone |
RNA polymerase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Bangladesh Medical Research Council (BMRC) |
|
Bangladesh |
2020-05-31 |
2020-07-31 |
29318042020, NCT04402203 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
2 Months |
50 |
Ahmedul Kabir, MBBS, FCPS FACP, FRCP, Ahmedul Kabir, MBBS, FCPS, FACP, FRCP, Md. Billal Alam, MBBS, FCPS MD, MACP, FACP |
2020-05-29 |
| CALYPSO: COVID-19 Associated Lymphopenia Pathogenesis Study in Blood |
Coronavirus disease 19 infection, Lymphocytopenia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Institute of Allergy and Infectious Diseases |
National Institutes of Health Clinical Center |
US |
2020-05-22 |
2022-06-30 |
20-I-0111, 200111, CALYPSO, NCT04401436 |
Phase Not Applicable |
Recruiting |
2 |
25 Months |
165 |
Irini Sereti, M.D., Princy Kumar, M.D. |
2020-05-29 |
| A study to know the effect of Ayurvedic Kwath(Kiratiktadi Kwath) and Ashwagandha Churna along with yoga exercises in the treatment of COVID-19 Positive patients |
Coronavirus disease 19 infection |
Variable regimens including Ashwagandha churna , Kiratiktadi Kwath |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
GS Ayurveda Medical College & Hospital |
|
India |
2020-06-02 |
|
CTRI/2020/05/025341 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
30 |
Ankur Singhal |
2020-06-02 |
| Efficacy of vitamin D treatment in patients diagnosed with pneumonia who require hospital admission and have vitamin D deficiency and a positive diagnosis for SARS-Cov-2 (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia, Vitamin D deficiency |
Hidroferol alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Investigation Institute Bioaraba |
|
Spain |
2020-05-25 |
|
2020-001960-28, RCTVITD/SARS-CoV-19 |
Phase 4 Clinical |
Recruiting |
1 |
|
108 |
Inés Pérez Francisco |
2020-05-29 |
| Nigella Sativa in COVID-19 |
Coronavirus disease 19 infection, Upper respiratory tract infection |
Nigella sativa seed oil alone, standard care protocol alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
King Abdulaziz University |
|
Saudi Arabia |
2020-05-21 |
2020-12-31 |
266-20, NCT04401202 |
Phase 2 Clinical |
Recruiting |
1 |
7 Months |
200 |
Abdulrahman Koshak, Dr, Dr Abdulrahman E. Koshak |
2020-05-29 |
| SARSCoV2CZPrev: COVID-19: Herd Immunity Study in the Czech Republic |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Institute of health information and statistics of the Czech Republic |
Central Military Hospital, Prague, Charles University, Czech Academy of Sciences, Czech Statistical Office, Faculty Hospital Olomouc, General University Hospital, Prague, Institut Klinické a Experimentální Medicin, Krajská zdravotní, a.s., Ústí nad Labem Region Hospitals, MasaryKuv Onkologicky Ustav, Masaryk University, Ministry of Health, Czech Republic, Palacky University, University Hospital Brno, University of Defence in Brno, University of Ostrava, Univerzita Jana Evangelisty Purkyne Prirodovedecka Fakulta |
Czech Republic |
2020-04-23 |
2020-05-01 |
NCT04401085, SARSCoV2CZPrev, UZIS 2020/1 |
Phase Not Applicable |
Completed |
1 |
|
27000 |
Aleksi Šedo, Prof., Dalibor Valík, Prof., David Feltl, Prof., Jarmila Rážová, M.D., Ph.D., Jaroslav Štěrba, Prof., Ladislav Dušek, Prof., Marián Hajdúch, Assoc. Prof., Martin Repko, Prof., Rastislav Maďar, Assoc. Prof., Roman Chlíbek, Prof., Roman Prymula, Prof., Vladimír Černý, Prof., Věra Adámková, Prof., Zdeněk Havel, Assoc. Prof. |
2020-06-02 |
| Multicenter, randomized, open-label study to evaluate the efficacy and safety of SOC + sarilumab versus standard of care for the early treatment of COVID-19-pneumonia in hospitalized patients |
Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia |
sarilumab alone, standard of care alone |
IL-6 receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universidad Autonoma de Madrid |
SANOFI-AVENTIS, S.A |
Spain |
2020-05-25 |
|
2020-002037-15, SARTRE |
Phase 2 Clinical |
Recruiting |
1 |
|
200 |
Belen Ruiz Antorán |
2020-05-29 |
| ACTIVATE II: BCG Vaccination to Prevent COVID-19 |
Coronavirus disease 19 infection |
BCG vaccine (Serum Institute of India Pvt. Ltd) alone |
|
Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hellenic Institute for the Study of Sepsis |
|
Greece |
2020-05-26 |
|
2020-002448-21, ACTIVATE II, ACTIVATEII |
Phase 4 Clinical |
Recruiting |
1 |
|
900 |
President of the Board |
2020-05-29 |
| Using GM-CSF as a Host Directed Therapeutic Against COVID-19 |
Coronavirus disease 19 infection, Hypoxia, Respiratory failure, Viral pneumonia |
sargramostim alone, standard of care alone |
CSF-1 agonist, GM-CSF receptor agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Singapore General Hospital Pte Ltd |
|
Singapore |
2020-06-30 |
2022-06-30 |
NCT04400929, SH-LEUK-01 |
Phase 2 Clinical |
Recruiting |
1 |
24 Months |
30 |
Jenny Low, MBBS |
2020-06-01 |
| Colchicine for the Treatment of Hyperinflammation Associated with Pneumonia due to COVID-19 |
Coronavirus disease 19 infection, Inflammatory disease, Viral pneumonia |
colchicine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Spanish Society of Cardiology |
|
Spain |
2020-05-25 |
|
2020-001841-38, Col-VID |
Phase 3 Clinical |
Recruiting |
1 |
|
240 |
Alberto Cecconi |
2020-05-29 |
| Impact of remote audio-visual surveillance of doffing process during COVID 19 pandemic on the safety of health care workers |
Coronavirus disease 19 infection |
remote audio-visual surveillance alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Postgraduate Institute of Medical Education and Research |
|
India |
2020-05-30 |
|
CTRI/2020/05/025274 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
AJAY SINGH |
2020-05-29 |
| Role of Chyawanprash in the prevention of COVID-19 in health care workers |
Coronavirus disease 19 infection |
Chyawanprash alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Central Council for Research in Ayurveda and Siddha |
|
India |
2020-05-30 |
|
CTRI/2020/05/025275 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
200 |
Dr Arun Gupta, Prof Dr Vidula Gujjarwar |
2020-05-29 |
| Effect of Ayurvedic intervention in COVID-19 positive cases |
Coronavirus disease 19 infection |
Variable regimens including Amalaki Churna , Golden Milk , Nagaradi kwath , Sanshamani Vati |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Chaudhary Brahm Prakash Ayurved Charak Sansthan |
|
India |
2020-05-29 |
|
CTRI/2020/05/025276 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
50 |
Dr Arun Gupta, ProfDr Vidula Gujjarwar |
2020-05-29 |
| Attitude of Egyptian Population Toward COVID-19 in Ramadan |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted |
Damanhour University |
|
Egypt |
2020-04-24 |
2020-10-31 |
COVID 19 IN RAMADAN, NCT04401072 |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
500 |
Amira Kassem, PHD, Amira kassem, PHD, Noha El bassiouny, PHD, Noha el bassiouny, PHD |
2020-05-28 |
| DECORE: Increased Risk of SARS-CoronaVirus-2 (SARS-CoV-2) Infection Associated With Endoscopy |
Coronavirus disease 19 infection |
abdominal ultrasound alone, gastrointestinal endoscopy alone, telephonic medical visit alone |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Hospital del Río Hortega |
|
Spain |
2020-05-11 |
2020-06-30 |
003, DECORE, NCT04401033 |
Phase Not Applicable |
Recruiting |
1 |
1 Month |
450 |
Manuel Pérez-Miranda Castillo, MD PhD, Marina De Benito, MD, Marina de Benito Sanz, Marina de Benito Sanz, MD |
2020-05-28 |
| SU-REM-COVID: Study results of Ayurvedic treatment on COVID patients using proprietary herbal formulation SUVED and whole colostrum REIMMUGEN |
Coronavirus disease 19 infection |
REIMMUGEN plus SUVED |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Health Solutions, India |
|
India |
2020-05-30 |
|
CTRI/2020/05/025343, SU-REM-COVID |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
30 |
Shreepad Bhat, Sujata Vaidya |
2020-06-02 |
| SARS-CoV-2 in Malaysia |
Coronavirus disease 19 infection |
|
|
|
Institute For Medical Research (Inc In Malaysia), University of Malaya |
|
Malaysia |
2020-03-17 |
|
54197, NMRR-20-536-54197 |
Phase Not Applicable |
Not yet recruiting |
2 |
|
3000 |
Dr Norazah binti Ahmad, Professor Dr Jamal I-Ching Sam |
2020-05-28 |
| Effects of Temperature and Humidity on the Transmission of SARS-CoV-2: A Systematic Review Protocol |
Coronavirus disease 19 infection |
|
|
|
National Institutes of Health Malaysia, Universiti Kebangsaan Malaysia |
|
Malaysia |
2020-04-17 |
2020-04-24 |
NMRR-20-725-54662 |
Phase Not Applicable |
Status not specified |
2 |
|
|
Dr CHANDRIKA JEEVANANTHAN, Dr Nor Asiah Muhamad, Dr. Rimah Melati binti Ab. Ghani |
2020-06-02 |
| Binding Potentials of Probiotics to SARS-COV-2 Spike Proteins |
Coronavirus disease 19 infection |
|
|
|
Universiti Sains Malaysia |
|
Malaysia |
2020-04-20 |
2021-04-19 |
54688, NMRR-20-758-54688 |
Phase Not Applicable |
Not yet recruiting |
5 |
12 Months |
100 |
Prof Dr Liong Min Tze |
2020-06-02 |
| A clinical trial of DNA vaccine for the potential treatment of novel coronavirus (Coronavirus disease 19 infection) |
Coronavirus disease 19 infection |
DNA vaccine alone |
|
|
AnGes MG Inc |
|
|
2020-07-31 |
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-06-01 |
| A multicenter registry analysis on the use of hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19 |
Coronavirus disease 19 infection |
chloroquine alone, hydroxychloroquine alone, Variable regimens including chloroquine , hydroxychloroquine , macrolide |
|
|
Brigham & Women's Hospital |
|
US |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
96032 |
|
2020-05-28 |
| A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of EB05 + SOC versus Placebo + SOC in Adult Hospitalized Patients With Moderate to Severe COVID-19 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
EB-05 alone, standard of care alone |
TLR-4 antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Edesa Biotech Inc |
JSS Medical Research Inc |
|
2020-07-31 |
2020-10-31 |
EB05-01-2020, NCT04401475 |
Phase 2 Clinical |
Not yet recruiting |
0 |
3 Months |
510 |
Blair Gordon, PhD |
2020-05-28 |
| BAT IT: Anti-SARS Cov-2 T Cell Infusions for COVID-19 |
Coronavirus disease 19 infection |
anti-SARS Cov-2 T Cell alone, Tylenol plus cetirizine |
Histamine H1 receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Baylor College of Medicine |
AlloVir, Center for Cell and Gene Therapy, Houston Methodist |
US |
2020-07-30 |
2021-08-15 |
BAT IT, H-47739 BAT IT, NCT04401410 |
Phase 1 Clinical |
Not yet recruiting |
1 |
12 Months |
20 |
Premal Lulla, Premal Lulla, MD |
2020-05-27 |
| CO-Qo-ICU: One-year Outcomes in Survivors of the Severe COVID-19 Pneumonia |
Coronavirus disease 19 infection, Hypoxia, Respiratory distress syndrome, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire De Nice |
|
France |
2020-06-16 |
2021-06-15 |
20REAMEDCOVID04, CO-Qo-ICU, NCT04401111 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
150 |
Clément SACCHERI, Jean DELLAMONICA, Jean DELLAMONICA, MD, PhD |
2020-05-27 |
| LOVIT-COVID: Lessening Organ Dysfunction With Vitamin C - COVID-19 |
Coronavirus disease 19 infection |
vitamin C alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universite de Sherbrooke |
Lotte & John Hecht Memorial Foundation |
Canada |
2020-06-30 |
2022-01-31 |
LOVIT-COVID, MP-31-2021-3741, NCT04401150 |
Phase 3 Clinical |
Not yet recruiting |
1 |
19 Months |
800 |
François Lamontagne, MD, FRCPC, MSc, Julie Menard, PhD, Marie-Helene Masse, Neill K Adhikari, MDCM, FRCPC, MSc |
2020-05-28 |
| COVID-Recovery: Recovery of Patients From COVID-19 After Critical Illness |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Australian and New Zealand Intensive Care Research Centre |
The Alfred (AU) |
Australia |
2020-05-31 |
2022-04-30 |
COVID-RECOVERY V1.0 01MAY2020, COVID-Recovery, NCT04401254 |
Phase Not Applicable |
Not yet recruiting |
7 |
23 Months |
300 |
Carol Hodgson, PhD, Natalie Linke, RN |
2020-05-27 |
| Cardiac Manifestation of Covid-19 Patients in Children |
Coronavirus disease 19 infection, Kawasaki disease |
echocardiography alone |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Universiti Putra Malaysia |
|
Malaysia |
2020-05-22 |
2020-05-30 |
55099, NMRR-20-1018-55099 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
7 |
dr putri bt yubbu |
2020-05-27 |
| Treatment of Lung Injury From COVID-19 Infection With Intravenous Sodium Nitrite |
Coronavirus disease 19 infection, Lung injury, Respiratory failure |
sodium nitrite (intravenous, sickle cell disease/myocardial infarction/cerebral vasospasm), Hope Pharmaceuticals alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hope Pharmaceuticals Inc |
|
|
2020-06-30 |
2020-12-31 |
NCT04401527, SN02-01 |
Phase 2 Clinical |
Not yet recruiting |
0 |
6 Months |
200 |
Hope Pharmaceuticals Medical Director |
2020-05-28 |
| NGS SARS-CoV-2 |
Coronavirus disease 19 infection |
|
|
|
National Institutes of Health Malaysia |
|
Malaysia |
2020-05-18 |
2021-12-31 |
54816, NMRR-20-884-54816 |
Phase Not Applicable |
Status not specified |
1 |
19 Months |
|
Dr Jeyanthi a/p Suppiah |
2020-05-27 |
| In vitro COVID-19 Anti-Viral Screening of Herbal Formulations |
Coronavirus disease 19 infection |
herbal formulation therapy alone |
|
|
National Institutes of Health Malaysia |
|
Malaysia |
2020-05-18 |
2020-12-31 |
54715, NMRR-20-874-54715 |
Phase Not Applicable |
Status not specified |
1 |
7 Months |
|
Dr Mohd Ridzuan Bin Mohd Abd Razak |
2020-05-27 |
| Characteristics of Neonatal Covid-19 in Turkey |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Newborn Infants (up to 5 months) |
Recep Tayyip Erdogan University Training and Research Hospital |
Turkish Neonatal Society |
Turkey |
2020-05-01 |
2020-10-30 |
NCT04401540, NICU-COVID-TR |
Phase Not Applicable |
Recruiting |
1 |
5 Months |
90 |
Mehmet K Kanburoglu, M.D., Mehmet Kenan Kanburoglu, Mehmet Y Oncel, M.D. |
2020-05-28 |
| The Efficacy Comparing Daily and After-each-case Room Disinfection |
Coronavirus disease 19 infection |
after-each-case room disinfection alone, daily room disinfection alone |
|
|
The First Affiliated Hospital of Zhejiang Chinese Medical University |
|
China |
2020-05-25 |
2020-06-10 |
DACD-HUY-2005, NCT04399005 |
Phase Not Applicable |
Recruiting |
1 |
|
240 |
Bin Lu, Bin Lu, M.D., Bo Jin, Bachelor, Liang Huang, Liang Huang, Bachelor, Yue Hu, Yue Hu, M.D. |
2020-05-28 |
| SARS-CoV-2, Nasopharygeal swab, Saliva |
Coronavirus disease 19 infection |
RT-PCR alone |
|
|
Institute For Medical Research (Inc In Malaysia) |
|
Malaysia |
2020-05-05 |
2020-06-30 |
54884, NMRR-20-860-54884 |
Phase Not Applicable |
Status not specified |
1 |
1 Month |
|
Dr Mohan Rao Nageswara Rao |
2020-05-27 |
| Cardiopulmonary Inflammation and Multi-System Imaging During the Clinical Course of COVID-19 Infection in Asymptomatic and Symptomatic Persons |
Coronavirus disease 19 infection, Inflammatory disease, Pulmonary heart disease |
CT scans alone, MRI scans alone, biological sampling alone, bronchoscopy alone, ultrasound alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Institutes of Health Clinical Center |
|
US |
2020-05-21 |
2024-05-01 |
20-CC-0113, 200113, NCT04401449 |
Phase Not Applicable |
Recruiting |
1 |
47 Months |
92 |
Anthony F Suffredini, M.D. |
2020-05-27 |
| A phase II, randomized, placebo-controlled study to evaluate the safety and efficacy of KT-PC-301 for the treatment of acute respiratory distress syndrome symptoms in patients with moderate to severe COVID-19 infection |
Coronavirus disease 19 infection, Respiratory distress syndrome |
KT-PC-301 alone |
|
|
Koligo Therapeutics Inc |
|
US |
|
|
|
Phase 2 Clinical |
Planned |
1 |
|
75 |
Mohamed Saad |
2020-05-27 |
| ICUCOVID-MY |
Coronavirus disease 19 infection |
|
|
|
University Malaya Medical Centre |
|
Malaysia |
2020-05-31 |
2020-09-30 |
54772, NMRR-20-1037-54772 |
Phase Not Applicable |
Recruiting |
1 |
4 Months |
|
ABDUL JABBAR BIN ISMAIL, Dr Nor Azim bin Mohd Yunos |
2020-06-02 |
| OVID: Enoxaparin for Primary Thromboprophylaxis in Ambulatory Patients With COVID-19 |
Blood clotting disorder, Coronavirus disease 19 infection |
enoxaparin sodium alone |
Low molecular weight heparin |
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Zurich |
Centre Hospitalier Universitaire Vaudois, Clinica Luganese Moncucco, Hopitaux Universitaires De Geneve, Oncology Institute of Southern Switzerland, University Hospital Basel, University Hospital Inselspital, Berne |
Switzerland |
2020-06-01 |
2021-04-14 |
NCT04400799, OVID, OVID TRIAL |
Phase 3 Clinical |
Not yet recruiting |
1 |
10 Months |
1000 |
Nils Kucher, Prof., Rebecca Spescha, Dr. sc. nat. |
2020-05-27 |
| A clinical trial of inactivated vaccine (COVID-19), KM Biologics for the potential treatment of COVID-19 infection |
Coronavirus disease 19 infection |
inactivated vaccine (COVID-19), KM Biologics alone |
|
|
KM Biologics Co Ltd |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-05-29 |
| Changing Of Egyptian Population Behavior Towards COVID-19 Outbreak |
Coronavirus disease 19 infection |
online survey alone |
|
Healthy volunteers accepted |
Damanhour University |
|
Egypt |
2020-05-02 |
2021-04-01 |
COVID 19, NCT04401098 |
Phase Not Applicable |
Recruiting |
1 |
11 Months |
700 |
Amira Kassem, PHD, Amira kassem, PHD, Noha El Bassiouny, PHD, Noha El bassiouny, PHD |
2020-05-27 |
| HEP-COVID: Full Dose Heparin Versus Prophylactic Or Intermediate Dose Heparin in High Risk COVID-19 Patients |
Coronavirus disease 19 infection |
enoxaparin sodium alone |
Low molecular weight heparin |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Northwell Health Inc |
|
US |
2020-04-26 |
2021-04-26 |
20-0340, HEP-COVID, NCT04401293 |
Phase 3 Clinical |
Recruiting |
6 |
12 Months |
308 |
Aaron Harrison, MD, Adrian Popp, MD, Alex C Spyropoulos, MD, Andrea Mignatti, MD, Barbara Shannon, RN, Christina Brennan, MD, Cynthia Price, NP, Damian Inlall, CCRC, Dana Kuziw, RN, Eugenia Gianos, MD, George Surguladze, MD, Gulru Sharifova, MD, Jane Hubert, RN, Janice Wang, MD, Jeremy Jacobson, MD, John Flynt, MD, Kevin Molina, Lisa Lumley, RN, Luis Gruberg, MD, Mangala Narasimhan, MD, Marc Cohen, MD, Mark Goldin, MD, Melissa Panzo, RN, Michael Krzyzak, MD, Nazish Ilyas, MD, Negin Hajizadeh, MD, Paul Maccaro, MD, Phyllis Suen, MD, Puneet Gandotra, MD, Richard Dima, MD, Sean Taylor, Wassim Diab, MD |
2020-05-28 |
| COVID-TRAUMA: Covid-19 and Reorganisation of Cancer Patient Care: Self-evaluation of Potential Post Traumatic Stress Disorder |
Coronavirus disease 19 infection, Post traumatic stress disorder |
Survey alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Institut Paoli-Calmettes IPC |
|
France |
2020-05-30 |
2020-11-30 |
COVID-TRAUMA, COVID-TRAUMA-IPC 2020-026, NCT04401046 |
Phase Not Applicable |
Not yet recruiting |
1 |
6 Months |
4000 |
Dominique Genre, MD, Gwenaelle GRAVIS, MD, Jihane PAKRADOUNI, PharmD, PhD |
2020-05-29 |
| Distance Learning for Dental Student During COVID-19 Pandemic |
Coronavirus disease 19 infection |
pediatric dentistry online course alone |
|
|
Cairo University |
|
Egypt |
2020-05-01 |
2020-05-10 |
DISTANCE LEARNING ENVIRONMENT, NCT04401371 |
Phase Not Applicable |
Completed |
1 |
|
418 |
Maha Moussa, Yasmin Mohamed Yousry |
2020-05-27 |
| Status of Management of Surgery in Beijing During COVID-19 |
Coronavirus disease 19 infection, Gastrointestinal disease |
surgery alone |
|
|
Beijing Friendship Hospital |
Beijing Chao-Yang Hospital, Beijing Hospital, China-Japan Friendship Hospital, Chinese PLA General Hospital, Peking Union Medical College Hospital, Peking University Cancer Hospital, Peking University First Hospital, Peking University Shougang Hospital, Peking University Third Hospital, People's Hospital Peking University, Xuanwu Hospital Of Capital Medical University |
China |
2020-05-25 |
2020-06-07 |
BFH-SURGERYCOVID, NCT04401124 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
500 |
Kai Pang, M.D., Zhongtao Zhang, M.D. |
2020-05-29 |
| MONACOVID: How Routine Biomarkers and Blood Leucocytes Count Can Assist Diagnosis of COVID-19 in Emergency Department |
Coronavirus disease 19 infection, Viral pneumonia |
CT-scan alone, naso-pharyngeal swab sampling alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Princesse Grace |
|
Monaco |
2020-02-01 |
2020-05-15 |
20-06, MONACOVID, NCT04401241 |
Phase Not Applicable |
Completed |
1 |
3 Months |
257 |
|
2020-05-28 |
| ACTT-II: Adaptive COVID-19 Treatment Trial 2 |
Coronavirus disease 19 infection |
baricitinib plus remdesivir |
COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, Jak1 tyrosine kinase inhibitor, Jak2 tyrosine kinase inhibitor, RNA polymerase modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Institute of Allergy and Infectious Diseases |
|
Japan, Singapore, US |
2020-05-08 |
2023-08-01 |
20-0006 ACTT-II, ACTT-II, NCT04401579 |
Phase 3 Clinical |
Recruiting |
48 |
38 Months |
1032 |
20-0006 Central Contact |
2020-05-28 |
| Randomized, Proof-of-Concept Trial to Evaluate the Safety and Explore the Effectiveness of Resveratrol for COVID-19 |
Coronavirus disease 19 infection |
Vitamin D3 plus resveratrol |
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Mount Carmel Health System |
|
US |
2020-06-30 |
2020-11-30 |
MCCREARY2020, NCT04400890 |
Phase 2 Clinical |
Not yet recruiting |
1 |
5 Months |
200 |
Marvin R McCreary |
2020-05-28 |
| Acute impairment of renal function in COVID-19: study on incidence, risk factors and mortality |
Coronavirus disease 19 infection, Renal failure |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Unidade de Pesquisa Clínica - Hospital das Clínicas da Faculdade de Medicina de Botucatu |
|
Brazil |
2020-05-01 |
|
30451520.6.0000.5411, CEP: 4.003.880, RBR-62y3h7, U1111-1251-0281 |
Phase Not Applicable |
Recruiting |
1 |
|
1000 |
Welder Zamoner |
2020-05-28 |
| Everett Clinic study: A clinical study to evaluate the efficacy of ID NOW COVID-19 Rapid Test |
Coronavirus disease 19 infection |
ID NOW COVID-19 Rapid Test alone |
|
|
Abbott Laboratories |
|
|
|
|
Everett Clinic study |
Phase Not Applicable |
Status not specified |
0 |
|
955 |
|
2020-05-29 |
| Urgent care clinic study: A multisite clinical study to evaluate the efficacy of ID NOW COVID-19 Rapid Test |
Coronavirus disease 19 infection |
ID NOW COVID-19 Rapid Test alone |
|
|
Abbott Laboratories |
|
|
|
|
Urgent care clinic study |
Phase Not Applicable |
Status not specified |
0 |
|
256 |
|
2020-05-29 |
| Long-term Pulmonary Outcomes After Infection With Sars-CoV-2 |
Coronavirus disease 19 infection |
Lung imaging alone, Pulmonary function test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Aarhus University |
|
Denmark |
2020-05-31 |
2022-12-31 |
33510, NCT04401163 |
Phase Not Applicable |
Not yet recruiting |
1 |
31 Months |
180 |
Elisabeth Bendstrup, MD, PhD, Søren S Haugen, MD |
2020-05-28 |
| PREVICHARM: Prevention of COVID-19 Infection in Nursing Homes by Chemoprophylaxis With Hydroxychloroquine |
Coronavirus disease 19 infection |
hydroxychloroquine (Dolquine) alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fundacion Publica Andaluza para la Investigacion de Malaga en Biomedicina y Salud, University of Malaga |
Instituto de Investigacion Biomedica de Malaga, Instituto de Salud Carlos III |
Spain |
2020-05-15 |
2021-04-01 |
2020-002287-31, COV20/00565, NCT04400019, PREVICHARM, PREVICHARM |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
3 |
10 Months |
1930 |
Gloria Luque, José M Morales-Asencio, PhD, José M Morales-Asencio, Professor, Juan C Morilla-Herrera, PhD, Ricardo Gómez-Huelgas, PhD |
2020-05-29 |
| TXA COVID-19 Clinical Trial |
Coronavirus disease 19 infection, Multiple organ failure, Renal injury |
TXA-127 alone |
Angiotensin II receptor modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Columbia University |
|
US |
2020-06-30 |
2021-12-31 |
AAAT0535, NCT04401423 |
Phase 2 Clinical |
Not yet recruiting |
1 |
18 Months |
100 |
Jeanine D'Armiento, Jeanine D'Armiento, MD, PhD, Laura Fonseca |
2020-05-29 |
| Mavrilimumab to Reduce Progression of Acute Respiratory Failure in COVID-19 Pneumonia and Systemic Hyper-inflammation |
Coronavirus disease 19 infection, Hypoxia, Inflammatory disease, Respiratory failure, Viral pneumonia |
mavrilimumab alone |
C-reactive protein inhibitor, Chemokine CC22 ligand inhibitor, GM-CSF receptor antagonist, Hemoglobin scavenger receptor antagonist, Metalloprotease-1 inhibitor, Metalloprotease-3 inhibitor, Small inducible cytokine A17 ligand inhibitor, VEGF gene inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cleveland Clinic Foundation |
Kiniksa Pharmaceuticals Ltd |
US |
2020-05-20 |
2021-05-31 |
IND 149324, IRB 20-523, NCT04399980 |
Phase 2 Clinical |
Recruiting |
2 |
12 Months |
60 |
Alice Goyanes, M. D., Calvin Sheng, M. D., Debases Sahoo, M.D., Narendrakumar Alappan, M. D., Ossama K Abou Hassan, M. D., Paul C Cremer, M. D., Prabalini Rajendram, M. D., Ravi Sunderkrishnan, M. D., Robier Aguillon-Prada, M. D., Shiddharth P Dugar, M. D., Tom Wang, M. D., Venu Menon, M. D., Yuki Kuramochi, BSN, RN |
2020-05-28 |
| Attitude and Perception Towards COVID-19 Pandemic |
Coronavirus disease 19 infection |
|
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Zagazig University |
|
Egypt |
2020-05-19 |
2020-08-31 |
NCT04400812, ZU#IRB#6138-17-5-2020 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
5000 |
Waheed Shouman |
2020-05-29 |
| Octagam 10% Therapy In COVID-19 Patients With Severe Disease Progression |
Coronavirus disease 19 infection |
Octagam 10% alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Octapharma AG, Octapharma USA |
|
US |
2020-06-01 |
2020-09-30 |
2020-002482-34, GAM10-10, NCT04400058 |
Phase 3 Clinical |
Not yet recruiting |
1 |
4 Months |
54 |
Mikaela Raymond |
2020-05-28 |
| Mechanisms of Multi-organ Failure in COVID-19 |
Coronavirus disease 19 infection, Multiple organ failure |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Imperial College London |
|
UK |
2020-05-18 |
2021-11-17 |
283783, NCT04399603 |
Phase Not Applicable |
Not yet recruiting |
1 |
18 Months |
120 |
|
2020-05-29 |
| Niclosamide for Mild to Moderate COVID-19 |
Coronavirus disease 19 infection |
niclosamide alone, standard of care alone, telehealth monitoring alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tufts Medical Center |
|
US |
2020-06-01 |
2020-11-30 |
NCT04399356, STUDY00000605 |
Phase 2 Clinical |
Not yet recruiting |
1 |
6 Months |
100 |
Dorothy Dulko, PhD, Harry P Selker, MD |
2020-05-28 |
| A retrospective, observational study to explore the clinical characteristics and prognosis of the new coronavirus 2019-nCoV patients combined with cardiovascular disease |
Cardiovascular disease, Coronavirus disease 19 infection |
angiotensin receptor blockers (ARBs) alone, angiotensin-converting enzyme inhibitors (ACEIs) alone |
|
|
Union Hospital Tongji Medical School Huazhong University Of Science & Technology |
|
China |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
112 |
|
2020-05-27 |
| Flow Controlled Ventilation in ARDS Associated With COVID-19 |
Adult respiratory distress syndrome, Coronavirus disease 19 infection |
Evone-ventilator alone, flow controlled ventilation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hamad Medical Corp |
|
Qatar |
2020-05-31 |
2020-08-31 |
MRC-05-018, NCT04399317 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
20 |
Marcus Lance, MD, PhD, Nabil Shallik, MD |
2020-05-29 |
| Ivermectin-Azithromycin-Cholecalciferol (IvAzCol) Combination Therapy for COVID-19 (IvAzCol) |
Coronavirus disease 19 infection, Respiratory disease |
Variable regimens including azithromycin , cholecalciferol , ivermectin |
Chloride channel modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Instituto De Seguridad Y Servicios Sociales De Los Trabajadores Del Estado |
|
Mexico |
2020-03-15 |
2020-06-10 |
IVAZCOL, NCT04399746 |
Phase 2 Clinical |
Recruiting |
1 |
2 Months |
30 |
Guadalupe Espitia Hernandez, MD, PhD, Guadalupe Espitia, MD, PhD |
2020-05-28 |
| Effect of Lactobacillus on the Microbiome of Household Contacts Exposed to COVID-19 |
Coronavirus disease 19 infection |
Lactobaciltus rhamnosus GG alone |
|
Healthy volunteers accepted, Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Duke University |
|
US |
2020-05-25 |
2022-05-25 |
NCT04399252, PRO00105674 |
Phase Not Applicable |
Not yet recruiting |
1 |
24 Months |
1000 |
Anthony Sung, MD, Lauren Bohannon |
2020-05-28 |
| Acceptance of Telemedicine During the COVID-19 Pandemic |
Coronavirus disease 19 infection |
telemedicine consultation alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Foundation for Health Research and Biomedical Valencia |
|
Philippines |
2020-06-01 |
2020-10-31 |
NCT04400448, TELECOVID |
Phase Not Applicable |
Not yet recruiting |
1 |
5 Months |
200 |
Luis Sánchez Guillen |
2020-05-29 |
| Evaluation effect of Dinvl for Covid19 infection |
Coronavirus disease 19 infection, Viral pneumonia |
dinvl, Health Medicine Chemistry Company alone, usual treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Baqiyatallah Hospital |
|
Iran |
2020-06-03 |
|
IR.BMSU.REC.1399.154, IRCT20200509047373N1 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
60 |
Ahmad Hosseinpour, Mohsen Saberi |
2020-05-29 |
| Evaluation efficacy of 'curcumin and resveratrol' capsule in controlling symptoms in patients with COVID-19 |
Coronavirus disease 19 infection |
curcumin + resveratrol alone, routine treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Bagheiat-allah University of Medical Sciences |
|
Iran |
2020-05-16 |
|
IR.BMSU.REC.1399.129, IRCT20080901001165N56 |
Phase 3 Clinical |
Recruiting |
1 |
|
60 |
Gholamhosein Alishiri, Morteza Izadi, Parisa Kianpour, Rouhollah Ahmadiyan, Yunes Panahi |
2020-05-29 |
| Cyclosporin for the Prevention and Treatment of COVID-19 Disease |
Coronavirus disease 19 infection, Respiratory failure |
cyclosporin alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shaheed Beheshti Medical University |
|
Iran |
2020-03-20 |
|
IR.SBMU.NRITLD.REC.1399.058, IRCT20150107020592N22 |
Phase 3 Clinical |
Recruiting |
1 |
|
60 |
Dr Seyyed Mohamadreza Hashemian, Seyed Mohammad Reza Hashemian |
2020-05-28 |
| Low dose whole lung irradiation for treatment of COVID-19 pneumonia |
Coronavirus disease 19 infection, Lung disease, Respiratory distress syndrome, Viral pneumonia |
low dose whole lung irradiation (100 Rads) alone |
|
Male, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tehran University of Medical Sciences |
|
Iran |
2020-05-27 |
|
IR.TUMS.VCR.REC.1399.362, IRCT20170211032494N3 |
Phase 2 Clinical |
Recruiting |
1 |
|
10 |
Dr. Mohammad Ali Sahraian, Nima Mousavi Darzikolaee |
2020-05-28 |
| Polio Vaccine and COVID-19 |
Coronavirus disease 19 infection |
oral polio vaccine (Razi Institute) alone |
|
|
Petroleum Industry Health Organization |
|
Iran |
2020-06-13 |
|
IR.SUMS.REC.1399.183, IRCT20140428017469N1 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
130000 |
Farrokh Habibzadeh, Habibollah Sami |
2020-05-28 |
| A Randomized Study to Assess the Effect of Genedrive 96 SARS-CoV-2 Kit in patients With COVID-19 |
Coronavirus disease 19 infection |
Genedrive 96 SARS-CoV-2 Kit alone |
|
|
Genedrive plc |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
180 |
|
2020-05-26 |
| EMPOWER: BAME versus COVID |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry, African Ancestry, Japanese Ancestry |
Future Genetics Limited |
|
UK |
2020-07-01 |
2021-10-01 |
EMPOWER, EMPOWER-BAME VS COVID, NCT04399733 |
Phase Not Applicable |
Not yet recruiting |
1 |
15 Months |
12800 |
Dr Mohammed Kamran, Kash Arfan |
2020-05-28 |
| Hydroxychloroquine of pharmacokinetics in healthcare workers |
Coronavirus disease 19 infection |
Hydroxychloroquine sulphate alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Indian Council of Medical Research |
|
India |
2020-05-25 |
|
83341, CTRI/2020/05/025242 |
Phase 1 Clinical |
Not yet recruiting |
1 |
|
400 |
Dr Nithya Gogtay |
2020-05-28 |
| A study on salivary samples and nasopharyngeal samples in diagnosis of COVID-19 Disease Patients |
Coronavirus disease 19 infection |
salivary and nasopharyngeal sampling alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Medanta The Medicity |
|
India |
2020-05-19 |
|
CTRI/2020/05/025243 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
40 |
Dr Sushila Kataria, Dr Vikas Deswal, Kuldeep K Chauhan |
2020-05-28 |
| Ashwagandha for prevention against SARS-CoV-2 Infection: A Randomized, Hydroxychloroquine Controlled drug trial in high risk Health Care Providers |
Coronavirus disease 19 infection |
Ashwagandha (Withania somnifera) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Council of Scientific and Industrial Research (India), Ministry of Ayush |
|
India |
2020-05-28 |
|
CTRI/2020/05/025332 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
400 |
DR ARVIND CHOPRA |
2020-06-02 |
| hCT-MSCs for COVID-19 ARDS |
Coronavirus disease 19 infection, Respiratory distress syndrome |
allogenic human cord tissue derived mesenchymal stromal cells (iv, ARDS/COVID-19), Duke University alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Duke University |
The Marcus Foundation Inc |
US |
2020-06-01 |
2021-07-31 |
NCT04399889, PRO00105410 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
14 Months |
30 |
Bryan Frank, MD, Jennifer Baker, RN, Joanne Kurtzberg, MD, Julie Lopez, MD |
2020-06-01 |
| To Study Clinical Characteristics, Treatment Outcome of Coronavirus (COVID-19) Patients |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
CIMS Hospital Pvt. Ltd. |
|
India |
2020-05-26 |
|
COVID-19/20-01, CTRI/2020/05/025247 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
500 |
Dr Amit Patel, Dr Hardik Shah, Dr Surabhi Madan |
2020-05-28 |
| To Study effectiveness and outcomes of Unani Medicine prophylactic interventions on population at risk of COVID-19 |
Coronavirus disease 19 infection |
Variable regimens including Khameera Marwareed , Tiryaq-e-Arba , Unani Joshanda |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Central Council for Research in Unani Medicine |
|
India |
2020-05-29 |
|
CCRUM 05/2020/01, CTRI/2020/05/025254 |
Phase 3 Clinical |
Not yet recruiting |
7 |
|
40000 |
Dr Ahmad Minhajuddin, Dr Arsheed Iqbal, Dr H A Lari, Dr Maqbool Ahmed, Dr Naheed Parveen, Dr Parvez Khan, Dr Pradeep Kumar, Dr Shagufta Parveen, Prof Abdul Wadood, Prof Asim Ali Khan |
2020-05-29 |
| An observational study on QT interval changes with Hydroxychloroquine used as prophylaxis in COVID exposure risk individuals |
Coronavirus disease 19 infection |
hydroxychloroquine alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Vydehi Institute of Nursing Sciences & Research CentreVydehi Institute of Nursing Sciences & Research Centre |
|
India |
2020-06-15 |
|
CTRI/2020/05/025289 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
50 |
P Vamsavardhana Reddy |
2020-05-28 |
| The Utility of Bedside Lung Ultrasonography on Diagnosis of COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
lung ultrasound alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Istanbul Bakirkoy Maternity and Children Diseases Hospital |
|
Turkey |
2020-05-10 |
2020-09-10 |
KSSEAH--, NCT04399681 |
Phase Not Applicable |
Recruiting |
1 |
4 Months |
100 |
Ramazan Guven, Seda Yilmaz Semerci |
2020-05-26 |
| Impact of effect of Ayurvedic treatment on novel Corona virus disease |
Coronavirus disease 19 infection |
Variable regimens including Anu Taila , Ashwagandha , Giloy Extract , Swasari Ras , Tulsi Extract |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
NIMS University, Patanjali Research Foundation |
|
India |
2020-05-29 |
|
CTRI/2020/05/025273 |
Phase 2 Clinical |
Recruiting |
1 |
|
120 |
Dr Abhishek Sharma, Dr Ganpat Devpura |
2020-05-28 |
| HPCOV-19: A study to assess the efficacy of Homoeopathic medicine in the prevention of Covid-19 |
Coronavirus disease 19 infection |
Arsenicum album 30 alone |
|
Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
District Homeopathic Medical Office |
|
India |
2020-05-30 |
|
CTRI/2020/05/025272, HPCOV-19 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
800 |
Dr Boban J, Dr Pramod P, Dr S Balamani |
2020-05-28 |
| Corona virus in tears |
Coronavirus disease 19 infection, SARS coronavirus infection |
|
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Maulana Azad Medical College |
|
India |
2020-05-24 |
|
CTRI/2020/05/025291 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
70 |
Dr RITU ARORA |
2020-05-26 |
| Ozone Therapy in the Prevention of COVID-19 Infection |
Coronavirus disease 19 infection |
Turkozone Blue-S medical ozone generator alone, ozone therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Marmara University |
|
Turkey |
2020-05-06 |
2020-05-17 |
2761, NCT04400006 |
Phase Not Applicable |
Completed |
1 |
|
71 |
Kardelen Gencer |
2020-05-26 |
| CIRCA-19: Cellular Immuno-Therapy for COVID-19 Acute Respiratory Distress Syndrome - Vanguard |
Coronavirus disease 19 infection, Respiratory distress syndrome |
allogeneic bone marrow-derived mesenchymal stem cell therapy (iv, septic shock/COVID-19/ADRS), Ottawa Hospital Research Institute alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ottawa Hospital Research Institute |
Stem Cell Network |
Canada |
2020-05-31 |
2021-06-30 |
20200243-01H, CIRCA-19, NCT04400032 |
Phase 1 Clinical |
Not yet recruiting |
1 |
13 Months |
9 |
Bernard Thebaud, MD, David Courtman, PhD, Dean Fergusson, PhD, Duncan J Stewart, MD, Manoj Lalu, MD, Shane English, MD |
2020-06-01 |
| Siddha Intervention Population Study |
Coronavirus disease 19 infection |
Kabasurakudineer Nilavembukudineer alone |
|
Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Central Council for Research in Siddha |
Ministry of Ayush |
India |
2020-05-25 |
|
CTRI/2020/05/025298 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
21500 |
DrKKanakavalli, PSathiyarajeswaran |
2020-05-26 |
| Study to assess efficacy of Ivermectin as prophylaxis of COVID -19 |
Coronavirus disease 19 infection |
ivermectin alone |
Chloride channel modulator |
Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
RD Gardi Medical College |
|
India |
2020-05-27 |
|
CTRI/2020/05/025333 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
2000 |
Dr Ashish Pathak, Dr Sunil Rathi |
2020-06-02 |
| The effects of Ginger on clinical manifestations and paraclinical features of patients with COVID-19: A randomized, double-blind, placebo-control clinical trial |
Coronavirus disease 19 infection |
Vomigone (Dineh Iran Pharmaceutical Company) alone, standard treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Bandare-abbas University of Medical Sciences |
|
Iran |
2020-05-21 |
|
IR.HUMS.REC.1399.130, IRCT20200506047323N1 |
Phase 3 Clinical |
Recruiting |
1 |
|
84 |
Mohammad Fathalipour, Parivash Davoodian, Teamur Aghamolaei |
2020-05-26 |
| Ayurveda as Prophylaxis for Suspected COVID-19 Patients |
Coronavirus disease 19 infection |
Ayurveda traetment alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
British Ayurvedic Medical Council |
All Party Parliamentary Group - Indian Traditional Sciences, Warwick University |
UK |
2020-06-10 |
2020-10-01 |
BAMC01, NCT04395976 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
120 |
Amarjeet S Bhamra, Avtar Singh, Jaydeep Joshi, Mahesh Mathpati, Mauroof Anthique, Neha Sharma, Shantha Godagama, Venkata Joshi, Vishwes Kulkarni |
2020-05-26 |
| Investigating the efficacy and safety of N-Acetyl Cysteine (NAC) inhalation spray in controlling the symptoms of patients with COVID-19 |
Coronavirus disease 19 infection |
N-acetyl-cysteine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Bagheiat-allah University of Medical Sciences |
|
Iran |
2020-05-13 |
|
IR.BMSU.REC.1399.123, IRCT20080901001165N55 |
Phase 3 Clinical |
Recruiting |
1 |
|
72 |
Dr. Rezaeiyan, Mostafa Ghanei, Parisa Kianpour, Yunes Panahi |
2020-05-26 |
| Vitamin D and COVID-19: Evaluation of the likely beneficial effects of vitamin D on infection with coronavirus |
Coronavirus disease 19 infection |
cholecalciferol alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fundación Para La Investigación E Innovación Biosanitaria En El Principado De Asturias (Finba) |
|
Spain |
2020-05-19 |
|
2020-002274-28, COVID-VIT-D, Vitamin D and COVID-19 |
Phase 4 Clinical |
Recruiting |
1 |
|
60 |
Managing director |
2020-05-27 |
| Convalescent Plasma in the treatment of 6 COVID-19 Patients |
Coronavirus disease 19 infection |
convalescent plasma alone |
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Affiliated Hospital of Zunyi Medical College, Guizhou Provincial Jiangjunshan Hospital |
|
China |
2020-01-29 |
2020-04-30 |
ChiCTR2000033056 |
Phase 0 Clinical |
No longer recruiting |
1 |
3 Months |
6 |
Zhang Wei |
2020-05-27 |
| The research of novel coronavirus pneumonia (COVID-19) patients' immune status and severity of disease |
Coronavirus disease 19 infection, Viral pneumonia |
Human immunoglobulin alone, Xuebijing alone, Human immunoglobulin plus Xuebijing |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
First Hospital of Changsha |
|
China |
2020-03-01 |
2021-03-01 |
ChiCTR2000033190 |
Phase 0 Clinical |
No longer recruiting |
1 |
12 Months |
60 |
Ailian Lv, Yuanlin Xie |
2020-05-27 |
| Novel coronavirus pneumonia (COVID-19) and Symptomatic Venous Thromboembolism: a Multicenter Retrospective Study |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
Union Hospital Tongji Medical School Huazhong University Of Science & Technology |
National Natural Science Foundation of China |
China |
2020-05-20 |
2020-05-30 |
ChiCTR2000033055 |
Phase Not Applicable |
Not yet recruiting |
15 |
|
300 |
Liang Tang, Yu Hu |
2020-06-02 |
| A randomized, open-label, blank-controlled, multicenter trial for Shuang-Huang-Lian oral solution in the treatment of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Lianhua Qingwen alone, shuanghuanglian oral solution alone, standard treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The First Affiliated Hospital of Wenzhou Medical University |
HPGC Renmintongtai Pharmaceutical Corporation |
China |
2020-02-12 |
2020-04-20 |
ChiCTR2000033133, ChiMCTR2000003320 |
Phase Not Applicable |
No longer recruiting |
1 |
2 Months |
60 |
Chen Yongping, Liu Cailing |
2020-05-27 |
| A follow-up study about clinically diagnosed cases of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The First Affiliated Hospital of Zhengzhou University |
Science and Technology Department of Henan Province |
China |
2020-02-01 |
2022-02-01 |
ChiCTR2000033186 |
Phase Not Applicable |
Recruiting |
2 |
24 Months |
118 |
An Xiaocai, Xu Aiguo |
2020-05-27 |
| Associations between suboptimal health status and TraditChinese Medicine constitution of medical staff fighting the disease, recovered COVID-19 patients and the general public under the outbreak of novel coronavirus pneumonia: an epidemiological study |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Southern Medical University |
|
China |
2020-05-20 |
2021-12-31 |
ChiCTR2000033108, ChiMCTR2000003319 |
Phase Not Applicable |
Recruiting |
1 |
19 Months |
600 |
Chen Jieyu, Zhao Xiaoshan |
2020-06-02 |
| Online parent training for reducing parenting stress during the coronavirus pandemic |
Acute stress disorder, Coronavirus disease 19 infection |
online forum sharing alone, online parent-training program alone, personal feedback alone |
|
Healthy volunteers accepted |
Heim Pal Children's Hospital |
Eotvos Lorand University |
Hungary |
2020-04-06 |
2020-12-15 |
2020/185, ISRCTN15254871 |
Phase Not Applicable |
Recruiting |
2 |
8 Months |
300 |
Dr Monika Miklosi |
2020-05-29 |
| Clinical characteristics and outcomes of novel coronavirus pneumonia (COVID-19) patients with pre-existing HBV infection |
Coronavirus disease 19 infection, Hepatitis B virus infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Institute of Field Surgery Third Military Medical University of the Chinese PLA |
|
China |
2020-05-01 |
2020-08-01 |
ChiCTR2000033107 |
Phase Not Applicable |
No longer recruiting |
1 |
3 Months |
72 |
Chen Dongfeng, Wang Wensheng, Wen Liangzhi |
2020-06-02 |
| CYCOV-II: Cytokine adsorption in patients with severe COVID-19 pneumonia requiring extracorporeal membrane oxygenation – randomized, controlled, open-label intervention, multicenter trial |
Coronavirus disease 19 infection, Viral pneumonia |
CytoSorb cytokine adsorber alone, venovenous extracorporeal membrane oxygenation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Klinikum der Albert-Ludwigs Universitaet Freiburg |
|
Germany |
2020-05-31 |
|
285/20, CYCOV-II, DRKS00021248, DRKS21300 |
Phase Not Applicable |
Not yet recruiting |
7 |
|
80 |
Alexander Supady |
2020-05-27 |
| COWUPAK: A prospective trial on the prevalence and the variation over time of SARS-CoV-2 antibodies in hospital health care workers (COVID-19) |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hygiene Helios Klinik Wuppertal |
|
Germany |
2020-05-12 |
|
94/2020, COWUPAK, DRKS00021729 |
Phase Not Applicable |
Recruiting |
1 |
|
300 |
Felix Giebel, Parviz Ahmad-Nejad |
2020-05-27 |
| Evaluation of the effect of thyme on corona patients |
Coronavirus disease 19 infection |
hospital protocol based medication treatment alone, thyme syrup (Gol Daru Company) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Zanjan University of Medical Sciences |
|
Iran |
2020-05-30 |
|
047IR.ZUMS.REC.1399, IRCT20200506047319N1 |
Phase 2 Clinical |
Recruiting |
1 |
|
100 |
Alireza Shoghli, Narjes Khavasi |
2020-06-01 |
| COVAYDE: COVid-19: Awake Proning and High-flow Nasal Cannula in respiratorY DistrEss |
Coronavirus disease 19 infection, Respiratory distress syndrome |
Awake Prone Positioning alone, nasal high-flow oxygen alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hopital de Verdun |
|
Canada |
2020-05-15 |
2020-12-31 |
2021-01, COVAYDE, NCT04395144 |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
346 |
Ivan Pavlov, MD |
2020-05-28 |
| COELIOCOVID: Risk of Air Contamination During Visceral Surgery in COVID19 Patients |
Coronavirus disease 19 infection, Respiratory tract infection |
Air sampling alone, biological fluid sampling alone, operating room surfaces sampling alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Regional Universitaire de Lille |
|
France |
2020-05-31 |
2020-10-31 |
2020-A01461-38, 2020_44, COELIOCOVID, NCT04395599 |
Phase Not Applicable |
Not yet recruiting |
1 |
5 Months |
40 |
Robert CAIAZZO, MD,PhD |
2020-05-28 |
| Follow up study of convalescent patients of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Union Hospital Tongji Medical School Huazhong University Of Science & Technology |
National Natural Science Foundation of China |
China |
2020-02-20 |
2021-02-20 |
ChiCTR2000033105 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
400 |
Huang Qi, Jin Yang |
2020-05-28 |
| Corona virus disease 2019 (COVID-19) antibody seroprevalence of the medical staff in the hospital with cluster of COVID-19 |
Coronavirus disease 19 infection |
Elecsys Anti-SARS-CoV-2 immunoassay alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
NTT West Osaka Hospital, Osaka City University Graduate School of Medicine, Osaka Police Hospital |
|
Japan |
2020-05-25 |
|
UMIN000040453 |
Phase Not Applicable |
Not yet recruiting |
2 |
|
2500 |
Atsushi Ogata |
2020-05-29 |
| A trial to assess nafamostat for COVID-19 infection |
Coronavirus disease 19 infection |
nafamostat (COVID-19 infection), Institut Pasteur Korea alone |
Serine protease inhibitor, Transmembrane serine protease 2 inhibitor |
|
Institut Pasteur Korea |
|
South Korea |
|
|
|
Phase Not Applicable |
Not yet recruiting |
1 |
|
|
Bae In-gyu |
2020-05-26 |
| Clinical study for rapid detection of novel coronavirus pneumonia (COVID-19) nucleic acid |
Coronavirus disease 19 infection, Viral pneumonia |
test reagent alone |
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hubei Zhongshan Hospital Affiliated to Wuhan University |
Anbio (Xiamen) Products Inc. |
China |
2020-03-07 |
2020-03-20 |
ChiCTR2000033104 |
Phase Not Applicable |
No longer recruiting |
1 |
|
|
Daming Wang, Yang Lei |
2020-05-27 |
| Usefulness of PCR testing for SARS-CoV-2 before gastrointestinal endoscopy and hospitalization |
Coronavirus disease 19 infection |
PCR testing alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Chiba University |
|
Japan |
2023-03-31 |
|
UMIN000040516 |
Phase Not Applicable |
Recruiting |
1 |
|
200 |
Naoya Kato, Yuki Ohta |
2020-05-27 |
| A randomized controlled trial for determination of the clinical effect of Internet-assisted pulmonary rehabilitation on patients with novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Internet-assisted pulmonary rehabilitation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The First Hospital Of China Medical University |
China Medical University (China) |
China |
2020-02-25 |
2020-09-01 |
ChiCTR2000033057 |
Phase Not Applicable |
Recruiting |
3 |
6 Months |
160 |
Gang Hou |
2020-05-27 |
| A 14-day, long prospective, multi-site, two-armed, randomized, open-label study is to investigate the effects of Vascepa on inflammatory biomarkers in individuals with COVID-19 |
Coronavirus disease 19 infection |
icosapent ethyl, Amarin alone |
Apolipoprotein B antagonist, Phospholipase A2 inhibitor |
|
Canadian Medical and Surgical Knowledge Translation Research Group, HLS Therapeutics Inc |
Amarin Corp plc |
Canada |
2020-05-31 |
|
|
Phase Not Applicable |
Planned |
1 |
|
100 |
Dr. Deepak L. Bhatt, Dr. Subodh Verma |
2020-05-26 |
| Investigating blood clotting changes in patients with COVID-19 |
Coronavirus disease 19 infection, Thrombosis |
|
|
|
Oxford University Hospitals NHS Trust |
|
UK |
2020-03-01 |
2020-11-30 |
14937, IRAS 282457, ISRCTN64783542 |
Phase Not Applicable |
Recruiting |
1 |
9 Months |
|
Dr Curry |
2020-05-27 |
| PICO: A pilot study of the ability of povidone-iodine (PVP-I) 0.5% aqueous solution oral/nasal spray and mouthwash to kill the SARS-CoV-2 virus in people with COVID-19 |
Coronavirus disease 19 infection |
mouthwash alone, povidone-iodine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Royal Surrey County Hospital NHS Trust |
British Association of Oral and Maxillofacial Surgeons, Royal Surrey County Hospital Charity, Surrey Peri-Operative Anaesthesia and Critical Care Collaborative Research Group (SPACER) |
UK |
2020-03-15 |
2020-07-30 |
IRAS 283182, ISRCTN13447477, PICO |
Phase 2 Clinical |
Recruiting |
1 |
4 Months |
25 |
Dr Justin Kirk-Bayley |
2020-05-26 |
| Psycho-behavioral response to the 2019-nCoV |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry |
The University of Hong Kong |
|
Hong Kong |
2020-02-04 |
|
20200131whpp, HKUCTR-2855, UW 20-120 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1000 |
Dr. Qiuyan Liao, HKUCTR Administrator |
2020-05-27 |
| BREATH-19: Clinical trial to evaluate the efficacy and safety of tocilizumab for treating patients with COVID-19 pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
tocilizumab (intravenous), Roche/Chugai alone |
IL-6 receptor antagonist, IL-6 receptor modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fundacion SEIMC-GESIDA |
ROCHE Espana |
Spain |
2020-05-15 |
|
2020-001995-13, BREATH-19, BREATH-19, FSG011-20 |
Phase 2 Clinical |
Recruiting |
1 |
|
500 |
Dynamic Science S.L., Raúl Montalbán Casado |
2020-05-26 |
| A study to determine if a new COVID-19 vaccine safely generates protective immune responses in adults in Kenya |
Coronavirus disease 19 infection |
AZD-1222 alone |
COVID19 Spike glycoprotein modulator |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
University of Oxford |
Wellcome Trust For Human Genetics |
Kenya |
2020-05-31 |
2022-05-31 |
PACTR202005681895696 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
24 Months |
400 |
George Warimwe, Marianne Munene, Philip Bejon |
2020-05-25 |
| Folic acid: A new suggested prevention and treatment of COVID-19 infection |
Coronavirus disease 19 infection |
folic acid alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cairo University |
|
Egypt |
2020-04-20 |
2020-05-21 |
PACTR202005599385499 |
Phase Not Applicable |
Not yet recruiting |
1 |
1 Month |
60 |
Ahmed Farag, Hala Salah, Nadia Ouda |
2020-05-25 |
| SARS-CoV-2 in Personal Protective Equipment |
Coronavirus disease 19 infection |
|
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Jose de San Martin Hospital de Clinicas |
|
Argentina |
2020-05-15 |
2020-07-30 |
NCT04398043, RT PCR EN EPP |
Phase Not Applicable |
Not yet recruiting |
1 |
2 Months |
16 |
Bernardo Bergroth, Bernardo bergroth, MD, Claudio Yaryour, MD |
2020-05-25 |
| An Investigation of the Efficacy and Safety of Favipiravir in COVID-19 Patients without Pneumonia − An open-label, randomized, controlled study |
Coronavirus disease 19 infection |
favipiravir alone, supportive care alone |
RNA polymerase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Faculty of Medicine Siriraj Hospital, Mahidol University, Health System Research Institute (HSRI) |
|
Thailand |
2020-06-01 |
|
TCTR20200514001 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
96 |
Rujipas Sirijatuphat |
2020-05-25 |
| Euro-COVIMID: Prevalence and Seroconversion of COVID-19 in Autoimmune Diseases in Europe |
Autoimmune disease, Coronavirus disease 19 infection, Rheumatoid arthritis, Sjoegrens syndrome, Spondylarthritis, Systemic lupus erythematosus, Temporal arteritis |
serological test alone, usual care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hopital Universitaire de la Pitie Salpetriere |
Rheumazentrum Ruhrgebiet, Universidad Complutense de Madrid, University College London, University of Coimbra, University of Ferrara |
France |
2020-05-31 |
2020-12-31 |
2020-A01371-38, Euro-COVIMID, NCT04397237 |
Phase Not Applicable |
Not yet recruiting |
1 |
7 Months |
3600 |
David Saadoun, MD, PhD, Laure Gossec, MD, PhD |
2020-05-25 |
| SMELLY: Prevalence of the loss of smell in patients with COVID-19 |
Coronavirus disease 19 infection, Olfactory nerve disorder |
University of Pennsylvania Smell Identification Test (UPSIT) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Royal North Shore Hospital |
|
Australia |
2020-05-03 |
2020-08-31 |
ACTRN12620000575932, SMELLY |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
100 |
A/Prof Roderick Clifton-Bligh, Ms Liza Nery |
2020-05-26 |
| Open, randomized, multicenter, comparative study of the efficacy and safety of the drug AREPLIVIR, film-coated tablets (OOO PROMOMED RUS, Russia) in patients hospitalized with COVID-19 |
Coronavirus disease 19 infection |
favipiravie (Areplivir), Promomed Rus alone |
|
|
Promomed Rus |
|
Russian Federation |
2020-05-21 |
2020-12-31 |
FAV052020 |
Phase 3 Clinical |
Status not specified |
5 |
7 Months |
210 |
|
2020-05-25 |
| Multicenter, open-label, randomized trial of the efficacy and safety of TL-FVP-t compared to standard therapy in parallel groups in patients with mild to moderate coronavirus infection (SARS-CoV-2/COVID-19) |
Coronavirus disease 19 infection |
favipiravir (TL-FVP-t), Technology of Medicines alone |
|
|
Technology of Medicines LLC |
|
Russian Federation |
2020-05-20 |
2022-12-31 |
TL-FVP-t-01 |
Phase 3 Clinical |
Status not specified |
7 |
31 Months |
200 |
|
2020-05-25 |
| BEAT COVID-19: Randomised clinical trial of interventions for the treatment of COVID-19 in the community setting for high risk older people |
Coronavirus disease 19 infection |
hydroxychloroquine alone |
|
Middle-aged Adults (45-64 yrs) |
University of Sydney |
National Health and Medical Research Council |
Australia |
2013-08-03 |
|
ACTRN12620000566932, BEAT COVID-19 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
3000 |
Ms Kate Wilson, Prof Guy Marks |
2020-05-25 |
| An international, multicenter, adaptive, randomized, open, controlled trial to evaluate the efficacy and safety of radotinib in the treatment of hospitalized patients with SARS-CoV-2 coronavirus infection (COVID-19) |
Coronavirus disease 19 infection |
radotinib alone |
Abl tyrosine kinase inhibitor, Bcr protein inhibitor, Tyrosine protein kinase ABL1 inhibitor |
|
Il-Yang Pharmaceutical Co |
|
Russian Federation |
2020-05-14 |
2021-04-30 |
CL01072079 |
Phase 3 Clinical |
Not yet recruiting |
8 |
11 Months |
180 |
|
2020-06-01 |
| ACT-20 in Patients With Severe COVID-19 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
ACT-20 alone, Conventional treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Aspire Health Science LLC |
|
|
2020-05-31 |
2020-10-31 |
AHS 20-03, NCT04398303 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
0 |
5 Months |
70 |
Laura Fairbairn |
2020-05-25 |
| ECMO-SARS: Extracorporeal Membrane Oxygenation (ECMO) and Coronavirus Disease (COVID) 19 |
Cardiac failure, Coronavirus disease 19 infection, Respiratory distress syndrome |
extracorporeal membrane oxygenation therapy alone |
|
|
Rennes University Hospital |
|
France |
2020-04-21 |
2020-10-21 |
35RC20_8979 ECMO-SARS, ECMO-SARS, NCT04397588 |
Phase Not Applicable |
Recruiting |
41 |
6 Months |
300 |
Alexandre OUATTARA, Professor, Alizée Porto, Doctor, André Vincentelli, Professor, André Vincentelli, professor, Antoine Guillon, Doctore, Bernard Cholley, Professor, Bertrand Rozec, Doctor, Bruno Levy, Professor, Claire Roger, Doctor, Claudio Barbanti, Doctor, Corentin Lacroix, Doctor, Cyril Cadoz, Doctor, Cécile Ferragu, DRI, Emmanuel Besnier, Doctor, François Labaste, Doctor, Guillaume Flicoteaux, Doctor, Gwenhaël COLIN, Doctor, Jean-Luc. Fellahi, Professor, Jerome Jouan, Doctor, Jordi Matiello, Doctor, Kais Brini, Doctor, Lucie Gaide-chevronnay, Doctor, Marc-Olivier FISCHER, Professor, Matthias CASTANIER, doctor, Nicolas Allou, Doctor, Nicolas BISCHOFF, Doctor, Nicolas D'OSTREVY, Doctor, Nicolas Mongardon, Doctor, Nicolas Nesseler, Doctor, Nicolas Nesseler, doctor, Olaf Mercier, professor, Olivier DESEBBE, Doctor, Olivier Fabre, Doctor, Olivier Fouquet, Doctor, Olivier Huet, professor, Philippe Gaudard, Doctor, Pierre Fillatre, Doctor, Pierre Guinot, Doctor, Pierre-Emmanuel Falcoz, Professor, Roxane NICOLAS, Sophie Provenchère, Doctor, Stéphane Aubert, Doctor, Vito Giovanni Ruggieri, Professor, Yannick Fedun, Doctor |
2020-05-25 |
| OHSCAR: Survival of patients suffering an out-of-hospital cardiac arrest treated by emergency services in Spain during the COVID-19 pandemic and One year later |
Cardiac arrest, Coronavirus disease 19 infection |
|
|
|
Andalusian School of Public Health, Sistema d'Emergències Mèdiques (SEM) |
|
Spain |
2020-01-23 |
2021-12-31 |
ISRCTN10437835, OHSCAR, OHSCAR 3 |
Phase Not Applicable |
Recruiting |
14 |
23 Months |
|
Dr RosellOrtiz |
2020-05-29 |
| Myocardial Injury and Major Adverse Outcomes in Patients With COVID-19 |
Coronavirus disease 19 infection, Heart injury |
|
|
|
Mount Sinai Medical Center |
|
US |
2020-05-31 |
2022-03-31 |
GCO 20-0965, NCT04397939 |
Phase Not Applicable |
Not yet recruiting |
2 |
22 Months |
5000 |
Annapoorna Kini, MD, Yuliya Vengrenyuk, PhD |
2020-05-26 |
| CO-QUETTES: COVID-19: Study of Inflammasome and Platelets Functions |
Coronavirus disease 19 infection, Viral pneumonia |
blood sampling alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire de Toulouse |
|
France |
2020-04-16 |
2021-04-30 |
CO-QUETTES, NCT04397822, RC31/20/0142 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
60 |
Fanny BOUNES |
2020-05-25 |
| NO-COVER: iNOPulse for COVID-19 |
Coronavirus disease 19 infection, Hypoxia, Viral pneumonia |
nitric oxide (inhaled, INOpulse), Bellerophon plus oxygen |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Miami |
Bellerophon Therapeutics LLC |
US |
2020-07-01 |
2021-01-15 |
20200449, NCT04398290, NO-COVER |
Phase 2 Clinical |
Not yet recruiting |
1 |
6 Months |
30 |
Roger A Alvarez, D.O. |
2020-05-25 |
| Intensive Care Associated Complications and Outcome of Acute Respiratory Distress Syndrome Due to COVID-19 |
Adult respiratory distress syndrome, Coronavirus disease 19 infection, Myopathy |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Inselspital, Berne |
|
Switzerland |
2020-04-09 |
2021-12-31 |
2020-00730, NCT04397172 |
Phase Not Applicable |
Recruiting |
1 |
20 Months |
50 |
Nicole Söll, Nicoles Söll, Werner Z`Graggen, MD |
2020-05-26 |
| Nebulized Heparin for the Treatment of COVID-19 Induced Lung Injury |
Adult respiratory distress syndrome, Coronavirus disease 19 infection, Lung injury |
nebulized heparin alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Frederick Memorial Hospital |
|
US |
2020-06-01 |
2020-12-31 |
FHHEP518, NCT04397510 |
Phase 4 Clinical |
Not yet recruiting |
1 |
7 Months |
50 |
Thomas Smoot, Thomas Smoot, PharmD |
2020-05-25 |
| PSYCOV-CV: Psychological Impact of COVID-19 Quarantine and Worsening of Cardiovascular Risk in the French General Population |
Acute stress disorder, Anxiety disorder, Cardiovascular disease, Coronavirus disease 19 infection, Depression |
|
|
Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire de Toulouse |
|
France |
2020-04-17 |
2021-04-20 |
NCT04397835, PSYCOV-CV, RC31/20/0135 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
800 |
Emilie Bérard, Emilie Bérard, MD PhD, Emilie Bérard, MD, PHD |
2020-05-25 |
| Mobile Health Study and Enhanced Symptom Monitoring in COVID-19 Cancer Patients |
Cancer, Coronavirus disease 19 infection |
chemotherapy alone, mHealth app alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Oklahoma |
|
US |
2020-06-30 |
2021-12-31 |
COVID-19 MOBILE HEALTH, NCT04397614 |
Phase Not Applicable |
Not yet recruiting |
1 |
18 Months |
500 |
Katherine Moxley, MD, Lead Oncology Nurse, Michael Businelle, PhD |
2020-05-25 |
| COG-UK HOCI: COG-UK Project Hospital-Onset COVID-19 Infections Study |
Coronavirus disease 19 infection |
Sample collection and genomic sequencing alone |
|
|
University College London |
COG-UK Consortium (UK), Public Health England |
UK |
2020-03-17 |
2021-04-30 |
20/EE/0118, COG-UK HOCI, CTU/2020/353, IRAS 283014, ISRCTN50212645, NCT04405934 |
Phase 3 Clinical |
Not yet recruiting |
4 |
13 Months |
2000 |
James Blackstone, Judith Breuer, MD, Leanne Hockey |
2020-06-01 |
| RT-PCR on Conjunctival Sample for the Detection of SARS-CoV-2 in Patients With Covid-19 |
Conjunctivitis, Coronavirus disease 19 infection |
Conjunctival RT PCR alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Versailles University Hospital |
|
France |
2020-05-15 |
2020-11-15 |
NCT04397666, P20/09, P20/09_COVEYES |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
68 |
Edouard KOCH, Edouard KOCH, coordonator investigator |
2020-05-25 |
| COVID3T: COVID-19 Thales Thermography Triage : Thermal Camera Feasibility Study |
Coronavirus disease 19 infection |
thermal camera alone, thermography alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
NHS Greater Glasgow and Clyde |
|
UK |
2020-05-20 |
2020-07-01 |
COVID3T, INGC20AE209, NCT04397380 |
Phase Not Applicable |
Not yet recruiting |
1 |
1 Month |
100 |
Barry Connor, PhD, Dan Forbes, MBChB, David J Lowe, MBChB, David Lowe, MBChB, Iain D Carrie, PhD, Malcolm WG Gordon, MBChb |
2020-05-26 |
| COMBAT-19: Mavrilimumab in Severe COVID-19 Pneumonia and Hyper-inflammation (COMBAT-19) |
Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia |
mavrilimumab alone, standard of care alone |
C-reactive protein inhibitor, Chemokine CC22 ligand inhibitor, GM-CSF receptor antagonist, Hemoglobin scavenger receptor antagonist, Metalloprotease-1 inhibitor, Metalloprotease-3 inhibitor, Small inducible cytokine A17 ligand inhibitor, VEGF gene inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ospedale San Raffaele |
|
Italy |
2020-05-22 |
2020-11-22 |
COMBAT-19, COMBAT-19, NCT04397497 |
Phase 2 Clinical |
Not yet recruiting |
3 |
6 Months |
50 |
Giacomo De Luca, MD, Lorenzo Dagna, MD |
2020-05-27 |
| CACOVID-19: The GCO-002 CACOVID-19 Cohort: a French, Nationwide, Multicenter Study of COVID-19 Infected Cancer Patients |
Anal tumor, Appendix adenoma, Biliary cancer, Bladder cancer, Brain tumor, Breast tumor, Central nervous system tumor, Colorectal tumor, Coronavirus disease 19 infection, Endometrioid carcinoma, Esophagus tumor, Gastrointestinal stromal tumor, Gastrointestinal tumor, Genitourinary tract tumor, Head and neck tumor, Larynx tumor, Liver tumor, Mesothelioma, Mouth tumor, Nasal cancer, Nasopharyngeal carcinoma, Neuroendocrine tumor, Non-small-cell lung cancer, Ovary tumor, Pancreas tumor, Peritoneal tumor, Pharynx tumor, Prostate tumor, Renal tumor, Salivary gland cancer, Skin cancer, Small intestine cancer, Small-cell lung cancer, Stomach tumor, Urinary tract tumor, Uterine cervix tumor, Vulvar intraepithelial neoplasia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Federation Francophone de Cancerologie Digestive |
ARCAGY/ GINECO GROUP, Association des Neuro-OnCologues d'Expression Francaise, Groupe Cooperateur Multidisciplinaire en Oncologie, Groupe Oncologie Radiotherapie Tete et Cou, IFCT |
France |
2020-04-03 |
2020-09-01 |
CACOVID-19, GCO002 CACOVID-19, NCT04397575 |
Phase Not Applicable |
Recruiting |
5 |
4 Months |
1000 |
Anne-Laure PELLETIER, Arnaud BOUTAN-LAROZE, Astrid LIEVRE, PhD, Carole VITELLIUS, Cécile GIRAULT, Gaël GOUJON, Jean-Baptiste BACHET, Julie PHILIP, O. Bouche, MD, Olivier LELEU, Touraj MANSOURBAKHT |
2020-05-27 |
| Study of the Safety of Therapeutic Treatment With Immunomodulatory MSC in Adults With COVID-19 Infection Requiring Mechanical Ventilation |
Coronavirus disease 19 infection, Respiratory distress syndrome |
BM-Allo-MSC alone, current supporting care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
NantKwest Inc |
Be The Match BioTherapies |
US |
2020-06-30 |
2021-06-30 |
NCT04397796, QUILT-COVID-19-MSC |
Phase 1b Clinical |
Not yet recruiting |
1 |
12 Months |
45 |
Lennie Sender, MD |
2020-06-02 |
| Blood Collection Study From COVID-19 Convalescents to Identify Immunogenic Viral Epitopes |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
TScan Therapeutics Inc |
|
US |
2020-04-09 |
2020-07-31 |
1586788, NCT04397900 |
Phase Not Applicable |
Recruiting |
2 |
3 Months |
80 |
Abby Richardson, Joana Achanfuo-Yeboah, CRA, Kenneth J Olivier, PhD |
2020-05-25 |
| Efficacy of Early Prone Positioning in Non-Mechanical Ventilation novel coronavirus pneumonia (COVID-19) Patients with Severe Hypoxia- a single-center prospective cohort study |
Coronavirus disease 19 infection, Hypoxia, Viral pneumonia |
prone position alone |
|
|
Tongji Medical College |
|
China |
2020-02-01 |
2020-03-31 |
ChiCTR2000033053 |
Phase 0 Clinical |
Completed |
1 |
2 Months |
60 |
Zang Xuefeng |
2020-05-25 |
| Effect of high dose intravenous vitamin C on moderate novel coronavirus pneumonia (COVID-19) patients: a medical records based retrospective study |
Coronavirus disease 19 infection, Viral pneumonia |
vitamin C alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Rui Jin Hospital |
|
China |
2020-01-01 |
2020-06-30 |
ChiCTR2000033050 |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
110 |
Bing Zhao, Enqiang Mao |
2020-05-25 |
| Effect of Laris - Hyssop combined herbal distilled on the improving clinical and paraclinical symptoms in patients with COVID-19 |
Coronavirus disease 19 infection |
Laris-Hyssop distillate alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Tabriz |
|
Iran |
2020-05-25 |
2020-07-20 |
IR.TBZMED.REC.1399.027, IRCT20200518047497N1 |
Phase Not Applicable |
Recruiting |
2 |
1 Month |
80 |
Azizeh Farshbaf-Khalili, Javad Ahmadian heris |
2020-05-29 |
| A clinical study for the efficacy and safety of artemisinin-pipequine tablets in the treatment of the mild or common type novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
artemisinin-piperaquine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Hongqi hospital of Mudanjing medical university |
Guangzhou University of Traditional Chinese Medicine |
China |
2020-05-19 |
2020-12-31 |
ChiCTR2000033049 |
Phase 4 Clinical |
Not yet recruiting |
1 |
7 Months |
|
Fengjie Xie, Hongying Zhang |
2020-05-25 |
| RECAP: Remote Monitoring of Cancer Patients With Suspected Covid-19 |
Coronavirus disease 19 infection, Hematological neoplasm, Sepsis, Solid tumor |
biosensor monitoring alone, continuous physiological ambulatory monitoring alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The Christie NHS foundation trust |
|
UK |
2020-06-30 |
2020-10-31 |
CFTSP186, NCT04397705, RECAP |
Phase 1 Clinical |
Not yet recruiting |
1 |
4 Months |
30 |
John Radford, Wes Dale |
2020-05-25 |
| COVID-19 PEP- High-risk Individuals in Long-term and Specialized Care - Canada |
Coronavirus disease 19 infection |
hydroxychloroquine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Lawson Health Research Institute |
|
Canada |
2020-05-19 |
2021-04-30 |
9881, NCT04397328 |
Phase 3 Clinical |
Not yet recruiting |
1 |
11 Months |
336 |
Michael J Borrie, MB ChB |
2020-05-25 |
| A clinical study of anti-SARS-CoV-2 mRNA lipid nanoparticle vaccine for the prevention of COVID-19 infection |
Coronavirus disease 19 infection |
anti-SARS-CoV-2 mRNA lipid nanoparticle vaccine (COVID-19), CanSino Biologics/ Precision NanoSystems alone |
|
|
CanSino Biologics Inc, Precision NanoSystems Inc |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-05-22 |
| Efficacy and Safety of COVID-19 Convalescent Plasma |
Coronavirus disease 19 infection |
anti SARS-CoV-2 convalescent plasma alone, plasmapheresis alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Institute for Transfusion Medicine of RNM |
University clinic of infectious diseases |
|
2020-04-30 |
2021-04-29 |
ITM05/2020MKD, NCT04397523 |
Phase 2 Clinical |
Recruiting |
0 |
12 Months |
20 |
Rada Grubovic Rastvorceva, MD MSci PhD, Sedulla Useini, MD |
2020-05-27 |
| A clinical study to assess the efficacy of Axen COVID-19 RT in detecting COVID-19 infection |
Coronavirus disease 19 infection |
Axen COVID-19 RT alone |
|
|
Macrogen Inc |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
|
|
2020-05-22 |
| A clinical study of AT-100 for the treatment of COVID-19 infection |
Coronavirus disease 19 infection |
AT-100, Airway alone |
Lung surfactant associated protein D modulator |
|
Airway Therapeutics LLC |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-05-22 |
| Phase I/II Clinical Trial of Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector) in Canada |
Coronavirus disease 19 infection |
Ad5-nCoV alone |
COVID19 Spike glycoprotein modulator |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
CanSino Biologics Inc, Canadian Center for Vaccinology, Canadian Immunization Research Network, National Research Council of Canada |
|
Canada |
2020-05-31 |
2021-08-31 |
AD5-NCOV-2020003, NCT04398147 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
15 Months |
696 |
Helen H Mao, PhD/MBA, Joanne M Langley, MD, Scott A Halperin, MD |
2020-05-29 |
| CCOVID-PREG: Characteristics of COVID-19 Infection Among Pregnant Women |
Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia |
RT-PCR test alone |
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Inova Health Care Services |
|
US |
2020-05-30 |
2021-03-17 |
CCOVID-PREG, NCT04398264, U20-05-4055 |
Phase Not Applicable |
Not yet recruiting |
1 |
9 Months |
100 |
Luis M Gomez, MD. MScE, Luis M. Gomez |
2020-05-25 |
| Inhaled NO for the Treatment of COVID-19 Caused by SARS-CoV-2 (US Trial) |
Coronavirus disease 19 infection |
LungFit system, Beyond Air alone, nitric oxide alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Beyond Air Ltd |
|
US |
2020-05-18 |
2020-09-30 |
BAI_COV19_01_US, NCT04397692 |
Phase 2 Clinical |
Not yet recruiting |
1 |
4 Months |
20 |
Ashik Tal, MD, Enoch Bortey, Priyantha Wijewardane, MD, Vladislava Zamfirova |
2020-05-29 |
| Immunological efficacy of lactic acid bacteria for COVID-19 |
Coronavirus disease 19 infection |
lactic acid bacteria alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Takanawa Pharma KK |
|
Japan |
2020-05-22 |
|
UMIN000040479 |
Phase Not Applicable |
Recruiting |
1 |
|
30 |
Tomoka Ebisui, Tsutomu Nakamura |
2020-05-28 |
| COVID-19 Convalescent Plasma for the Treatment of Hospitalized Patients With Pneumonia Caused by SARS-CoV-2 |
Coronavirus disease 19 infection, Respiratory disease, Viral pneumonia |
COVID-19 convalescent plasma alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Pennsylvania |
|
US |
2020-05-13 |
2020-11-13 |
843003 (PENNCCP-02), NCT04397757 |
Phase 1 Clinical |
Recruiting |
1 |
6 Months |
80 |
Julie Starr, Katharine J. Bar, Katharine J. Bar, MD |
2020-05-30 |
| A clinical trial of ADX-1612 in the treatment of patients with COVID-19 infection |
Coronavirus disease 19 infection |
ganetespib alone |
Hsp 90 inhibitor, Jak2 tyrosine kinase inhibitor, Kit tyrosine kinase inhibitor, STAT-3 inhibitor, STAT-5 inhibitor |
|
Aldeyra Therapeutics Inc |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-05-22 |
| COMET20d: A Study to Collect Bone Marrow for Process Development and Production of BM-MSC to Treat Severe COVID-19 Pneumonitis |
Coronavirus disease 19 infection, Pneumonia |
bone marrow harvest alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs) |
Cambridge Clinical Trials Unit |
Cambridge Cellular Therapies Laboratory, Cambridge University Hospitals NHS Foundation Trust, The Evelyn Trust |
UK |
2020-05-31 |
2021-12-31 |
COMET20D, COMET20d, NCT04397471 |
Phase Not Applicable |
Not yet recruiting |
1 |
19 Months |
10 |
Andrew McCaskie, FRCS, Charles Crawley, MD, Claire Mather, BSc, Purity Bundi, BSc |
2020-05-25 |
| Clinical record investigation about ADHD children because of COVID19 |
Coronavirus disease 19 infection |
|
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Chiba University |
|
Japan |
2020-05-21 |
|
UMIN000040476 |
Phase Not Applicable |
Recruiting |
1 |
|
10 |
Masaomi Iyo, Tsuyoshi Sasaki |
2020-05-25 |
| Effects of nokhod-ab on fatigue |
Coronavirus disease 19 infection, Fatigue |
nokhod-ab alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Semnan University of Medical Sciences |
|
Iran |
2020-05-31 |
|
IR.SEMUMS.REC.1399.031, IRCT20200115046144N2 |
Phase 3 Clinical |
Recruiting |
1 |
|
40 |
Ali Gohari, Bahareh Ahadi, Dr. Parviz Kokhaei |
2020-06-01 |
| Mental Health Outcomes in Healthcare Workers During COVID-19 |
Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder |
online survey alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The University Health Network |
Sunnybrook Health Sciences Centre, University of Toronto, William Osler Health System |
Canada |
2020-05-14 |
2020-06-24 |
3189, NCT04397848 |
Phase Not Applicable |
Recruiting |
1 |
1 Month |
1200 |
Laura Hawryluck, MD, Laura Hawryluck, MD, MSc, Rima Styra, MD, Rima Styra, MD, MEd |
2020-05-27 |
| HITCH: Hormonal Intervention for the Treatment in Veterans With COVID-19 Requiring Hospitalization |
Coronavirus disease 19 infection |
best supportive care (BSC) alone, degarelix alone |
GNRH receptor antagonist |
Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
VA Office of Research and Development |
|
US |
2020-06-01 |
2020-10-01 |
COVID19-8900-15, HITCH, NCT04397718 |
Phase 2 Clinical |
Not yet recruiting |
4 |
4 Months |
198 |
Bruce Montgomery, MD, Daniel Becker, MD, Elahe Mostaghel, MD, Matthew B Rettig, MD, Matthew B. Rettig, MD, Mohammad Al-Jam, MD, Nicholas G Nickols, MD PhD, Tsay Jun-Chieh |
2020-05-27 |
| RESPOND: Pathogenesis of BTK-mediated Hyper-Inflammatory Responses in COVID-19 |
Coronavirus disease 19 infection |
bruton tyrosine kinase inhibitor therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Institute of Allergy and Infectious Diseases |
National Institutes of Health Clinical Center |
US |
2020-06-04 |
2023-04-30 |
20-I-N114, 999920114, NCT04394884, RESPOND |
Phase Not Applicable |
Recruiting |
3 |
34 Months |
160 |
Ephraim Fuchs, M.D., Joe Roswarski, M.D., Michail S Lionakis, M.D. |
2020-06-02 |
| Combination With Alvelestat and Isotretinoin May Enhance Neutralizing Antibodies in COVID-19 Infected Patients Better Than COVID-19 Inactivated Vaccines (Antibodies) |
Coronavirus disease 19 infection, Respiratory failure, Respiratory tract infection |
alvelestat plus isotretinoin (aerosolized) |
Leukocyte elastase inhibitor |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Kafrelsheikh University |
Damietta University |
Egypt |
2020-06-30 |
2020-11-30 |
COVID-19, NCT04396067 |
Phase 2 Clinical |
Not yet recruiting |
1 |
5 Months |
360 |
M.Sc. Mahmoud Elkazzaz, M.Sc.in Biochemistry, M.Sc.Mahmoud Elkazzaz, Master of biochemistry |
2020-05-26 |
| Physical Activity Levels in COVID-19 Patients Admitted to Intensive Care |
Coronavirus disease 19 infection |
physiotherapy alone, rehabilitation alone, respiratory care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Birmingham NHS Foundation Trust |
|
UK |
2020-03-01 |
2020-05-08 |
NCT04396197, PHYSIOCOVID-19 |
Phase Not Applicable |
Completed |
1 |
2 Months |
92 |
David McWilliams |
2020-05-26 |
| ALLIANCE: International ALLIANCE Study of Therapies to Prevent Progression of COVID-19 |
Coronavirus disease 19 infection |
Variable regimens including Plaquenil , azithromycin , cholecalciferol , mecobalamin , sodium ascorbate , zinc citrate |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Institute of Integrative Medicine |
Catholic Health Initiatives |
Australia |
2020-05-25 |
2021-12-31 |
ALLIANCE, ALLIANCE-COVID19, NCT04395768 |
Phase 2 Clinical |
Not yet recruiting |
1 |
19 Months |
200 |
Karin Ried, PhD, Taufiq Binjemain, MD |
2020-05-27 |
| A Study of ResCure to Treat COVID-19 Infection |
Coronavirus disease 19 infection |
ResCure alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
ProgenaBiome |
Rinati Skin LLC |
US |
2020-05-31 |
2021-10-31 |
NCT04395716, PRG-048 |
Phase 1 Clinical |
Not yet recruiting |
1 |
17 Months |
50 |
Jordan Daniels, MS, Sabine Hazan, MD |
2020-06-01 |
| PAIN-COVID: Early Care Program for the Management of Post-ICU Syndrome and Chronic Pain After COVID-19 Infection |
Anxiety disorder, Coronavirus disease 19 infection, Depression, Pain, Post traumatic stress disorder |
psychological intervention alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Clinic of Barcelona |
|
Spain |
2020-05-25 |
2021-03-25 |
HCB/2020/0549, NCT04394169, PAIN-COVID |
Phase Not Applicable |
Not yet recruiting |
1 |
10 Months |
102 |
Antonio José Ojeda Niño, MD, Tomás Cuñat López, MD |
2020-05-21 |
| Patients Perspectives on Discontinuation of Their Fertility Treatment Due to the COVID-19 Pandemic |
Coronavirus disease 19 infection, Infertility |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Universitair Ziekenhuis Gent |
|
Belgium |
2020-05-14 |
2020-12-31 |
B6702020000247, BC-07783, NCT04396210 |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
2000 |
Frauke Vanden Meerschaut, MD, Rebecca De Beir, Msc |
2020-05-22 |
| Exercise Training and Sedentary Lifestyle on Clinical Outcomes in Patients With COVID-19 |
Coronavirus disease 19 infection |
exercise training alone |
|
Healthy volunteers accepted |
Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo |
|
Brazil |
2020-06-01 |
2021-01-20 |
COVID-19, NCT04396353 |
Phase Not Applicable |
Not yet recruiting |
1 |
7 Months |
850 |
Francis S Ribeiro, PhD, Marcelo R Santos, PhD |
2020-05-21 |
| PPRI: The Professional Peer Resilience Initiative |
Anxiety disorder, Coronavirus disease 19 infection, Post traumatic stress disorder |
MinnRAP peer support program alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Minnesota |
|
US |
2020-05-25 |
2022-05-25 |
NCT04396600, PPRI, STUDY00009564 |
Phase Not Applicable |
Recruiting |
1 |
24 Months |
1200 |
Cristina S Albott, MD, Sey Lee, BS |
2020-05-21 |
| PACCOVRA: Pediatric Acute and Critical Care COVID-19 Registry of Asia |
Coronavirus disease 19 infection |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
KK Women's and Children's Hospital |
Aichi Children's Health and Medical Center, Children's Hospital of Chongqing Medical University, General Hospital H. Adam Malik, Hyogo Prefectural Kobe Children's Hospital, King Chulalongkorn Memorial Hospital, National University Hospital (Singapore) Pte Ltd, Penang General Hospital, Postgraduate Institute of Medical Education and Research, Ramathibodi Hospital, Rumah Sakit Anak dan Bunda Harapan Kita, Singapore Clinical Research Institute, St Marianna University School of Medicine, Tokyo Metropolitan Childrens Medical Center Hospital, Vicente Sotto Memorial Medical Center - Public, Zhengzhou Children's Hospital |
Singapore |
2020-05-18 |
2023-12-31 |
2020/2094, NCT04395781, PACCOVRA |
Phase Not Applicable |
Not yet recruiting |
1 |
43 Months |
2000 |
Cecilia Chandra, Judith Ju Ming Wong |
2020-05-27 |
| Clinical Study for Efficacy of Anti-Corona VS2 Immunoglobulins Prepared From COVID19 Convalescent Plasma Prepared by VIPS Mini-Pool IVIG Medical Devices in Prevention of SARS-CoV-2 Infection in High Risk Groups as Well as Treatment of Early Cases of COVID19 Patients |
Coronavirus disease 19 infection |
Mini-Pool IVIG alone, anti-SARS-CoV-2 hyperimmune globulin therapy (COVID-19), Assiut University alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Assiut University |
|
Egypt |
2020-06-01 |
2021-01-01 |
MINI-POOLED IVIG IN COVID19, NCT04383548 |
Phase 2 Clinical |
Not yet recruiting |
1 |
7 Months |
100 |
Alia M Hussein, professor, Alshaimaa M Selim, specialist, Azza M Ez-Eldin, professor, Magdy El Ekiaby, Doctor, Maha A Mohamed, professor |
2020-05-28 |
| SAVE: A Phase II Study of the C3 Inhibitor AMY-101 in Patients With ARDS Due to COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
AMY-101 alone |
Complement C3 inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Amyndas Pharmaceuticals |
|
|
2020-07-31 |
2021-03-31 |
AMY-101_SAVE, NCT04395456, SAVE |
Phase 2 Clinical |
Not yet recruiting |
0 |
8 Months |
144 |
|
2020-05-21 |
| An Expanded Access Study to Provide at Home Subcutaneous Administration of Pertuzumab and Trastuzumab Fixed-Dose Combination (PH FDC SC) for Patients With HER2-Positive Breast Cancer During the COVID-19 Pandemic |
Breast tumor, Coronavirus disease 19 infection |
pertuzumab + trastuzumab (sc Enhanze, breast cancer), Roche alone |
Erbb2 tyrosine kinase receptor inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Genentech Inc |
|
US |
|
|
AL42478, NCT04395508 |
Phase Not Applicable |
Recruiting |
9 |
|
|
Clinical Trials |
2020-06-02 |
| Home Usability Study of the SARS-CoV-2 (COVID-19)Test |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Exact Sciences Corp |
|
US |
2020-05-18 |
2020-06-30 |
2020-06, NCT04395391 |
Phase Not Applicable |
No longer recruiting |
1 |
1 Month |
30 |
Steven Shak |
2020-06-01 |
| The effect of hot cupping on corona symptoms |
Coronavirus disease 19 infection |
hot cupping alone, azithromycin plus lopinavir + ritonavir |
HIV protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Mazandaran University of Medical Sciences |
|
Iran |
2020-05-04 |
|
IR.MAZUMS.REC.1399.162, IRCT20131129015584N3 |
Phase 2 Clinical |
Recruiting |
1 |
|
68 |
Assie Jokar, Dr Assie Jokar, Dr Majid Saidi |
2020-05-22 |
| TAC-COVID19: Lung CT Scan Analysis of SARS-CoV2 Induced Lung Injury |
Coronavirus disease 19 infection, Lung injury, Respiratory distress syndrome, Respiratory insufficiency, Viral pneumonia |
CT scan alone, deep learning algorithm-artificial intelligence technology alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Milano-Bicocca |
|
Italy, San Marino |
2020-04-15 |
2020-10-15 |
NCT04395482, TAC-COVID19, TAC-COVID19 |
Phase Not Applicable |
Recruiting |
8 |
6 Months |
500 |
Emanuele Rezoagli, Giacomo Bellani, Giovanni Vitale, Giuseppe Nardi, Luca Lorini, Mario Tavola, Massimo Arlotti, Matteo Subert, Savino Spadaro |
2020-05-27 |
| A phase II study of R-107 for the treatment of severe acute respiratory syndrome in COVID-19 |
Coronavirus disease 19 infection, SARS coronavirus infection |
R-107 alone |
|
|
Massachusetts General Hospital |
|
|
|
|
|
Phase 2 Clinical |
Planned |
0 |
|
|
|
2020-05-21 |
| Dexamethasone for COVID-19 Related ARDS: a Multicenter, Randomized Clinical Trial |
Coronavirus disease 19 infection, Respiratory distress syndrome |
dexamethasone alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centro de Educación Medica e Investigaciones Clínicas Norberto Quirno |
|
Argentina |
2020-05-21 |
2021-01-31 |
1264, NCT04395105 |
Phase 3 Clinical |
Recruiting |
1 |
8 Months |
284 |
Ignacio Bonelli, MD, Luis P Maskin, MD, Pablo O Rodriguez, MD, Stella Zarza, SC |
2020-05-26 |
| Sleep Quality in Healthcare Personnel During COVID-19 |
Coronavirus disease 19 infection |
web based online survey alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assiut University |
|
Egypt |
2020-03-30 |
2020-05-16 |
ASSIUTU14, NCT04395300 |
Phase Not Applicable |
Completed |
1 |
1 Month |
143 |
Aliae AR Mohamed Hussein |
2020-05-26 |
| COVIDIV: Collateral Damage From the COVID-19 Pandemic Observed in Patients Treated With Intravitreal Injections (IVT) of Anti-angiogenic Agents |
Coronavirus disease 19 infection, Diabetic macular edema, Retinal venous occlusion, Wet age related macular degeneration |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fondation Ophtalmologique Adolf De Rothschild |
|
France |
2020-05-31 |
2021-12-31 |
COVIDIV, MMT_2020_15, NCT04395859 |
Phase Not Applicable |
Not yet recruiting |
4 |
19 Months |
1500 |
Amélie YAVCHITZ, MD, Benjamin WOLFF, MD, Flore DE BATS, MD, Martine MAUGET FAYSSE, Martine MAUGET FAYSSE, MD, Ramin TADAYONI, MD |
2020-05-22 |
| Sexual Function During COVID-19 Pandemic |
Coronavirus disease 19 infection, Sexual dysfunction |
electronic questionnaire alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs) |
Assiut University |
|
Egypt |
2020-06-01 |
2020-08-31 |
NCT04395885, SFCOV |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
120 |
Ahmed Mohamed Abbas |
2020-05-22 |
| A clinical study of SARS-CoV-2 vaccine (VLP, COVID-19) for the potential prevention of SARS-CoV-2 infection (COVID-19) |
Coronavirus disease 19 infection |
SARS-CoV-2 vaccine (VLP, COVID-19), Medicago alone |
|
|
Medicago Inc |
|
Canada |
2020-08-31 |
|
|
Phase Not Applicable |
Planned |
1 |
|
|
|
2020-06-02 |
| COVID HELMET: Helmet CPAP Versus HFNC in COVID-19 |
Coronavirus disease 19 infection, Respiratory failure |
CaStar hood (Bio-Med Devices) alone, Helmet continuous positive airway pressure therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Lund |
Region Skane |
Sweden |
2020-05-31 |
2021-05-31 |
COVID HELMET, COVID HELMET, NCT04395807 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
120 |
Jonas Tverring, MD, Niklas Nielsen, MD PhD |
2020-05-22 |
| Psychiatric Consultation for COVID-19 Patients |
Coronavirus disease 19 infection, Psychiatric disorder |
psychiatric counseling alone |
|
|
Daegu Catholic University medical center |
|
South Korea |
2020-05-28 |
2020-12-31 |
CR-20-062, NCT04395872 |
Phase Not Applicable |
Not yet recruiting |
1 |
7 Months |
54 |
Jonghun Lee, M.D., ph.D., geunhui Won, M.D. |
2020-05-28 |
| TMF-COVID-19: Maternal-fetal Transmission of SARS-Cov-2 |
Coronavirus disease 19 infection |
RT-PCR SARS-Cov-2 test alone, blood sampling alone, electron microscopy alone, serology test alone, vaginal swab sampling alone |
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Centre Hospitalier Regional D'Orleans |
|
France |
2020-05-05 |
2021-05-31 |
CHRO-2020-10, NCT04395924, TMF-COVID-19 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
50 |
Aurélie DESPUJOLS, Elodie POUGOUE TOUKO, Souhail ALOUINI, Dr, Souhail ALOUINI, M.D., Ph.D. |
2020-06-01 |
| A clinical study of S-309 for the potential treatment and/or prevention of SARS-CoV-2 infection (COVID-19) |
Coronavirus disease 19 infection |
SARS-COV-2 targeting human monoclonal antibodies (COVID-19), Vir Biotechnology/ WuXi Biologics alone |
COVID19 Spike glycoprotein inhibitor |
|
Vir Biotechnology Inc |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-05-21 |
| Convalescent Plasma Compared to Anti-COVID-19 Human Immunoglobulin and Standard Treatment (TE) in Hospitalized Patients |
Coronavirus disease 19 infection |
COVID-19 convalescent plasma alone, anti-COVID-19 human immunoglobulin alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Lifefactors Zona Franca, SAS |
|
|
2020-06-30 |
2021-06-30 |
LFCOLCOVID-19-001, NCT04395170 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
0 |
12 Months |
75 |
Santiago Jaramillo |
2020-05-22 |
| TMX COVID: 1,3,7-Trimethylxanthine as a Treatment of COVID-19: Results of a Controlled Study |
Coronavirus disease 19 infection |
coffee containing 1,3,7-trimethylxanthine intake alone, tea and hot chocolate with milk intake alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire De Poitiers Etablissement D’Hospitalisation |
|
|
2020-05-31 |
2020-12-31 |
NCT04395742, TMX COVID, TMX COVID |
Phase Not Applicable |
Not yet recruiting |
0 |
7 Months |
93 |
Alexandre BLEIBTREU, Paul ROBLOT |
2020-05-22 |
| Impact of COVID-19 on Psychological Status in Case of IVF Interrupted or Postponed |
Coronavirus disease 19 infection, Female infertility |
|
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
IRCCS AOU San Martino – IST |
|
Italy |
2020-04-01 |
2020-05-15 |
COVID-19-NOIVF, NCT04395755 |
Phase Not Applicable |
Completed |
1 |
1 Month |
503 |
Fabio Barra |
2020-05-22 |
| ACOVID: Arrhythmias in Patients With COVID-19 |
Coronavirus disease 19 infection, Heart arrhythmia |
C3+ Holter Monitor alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Herlev and Gentofte Hospital, Denmark |
|
Denmark |
2020-04-16 |
2021-04-01 |
ACOVID, H-20021500, NCT04395664 |
Phase Not Applicable |
Recruiting |
1 |
11 Months |
1000 |
Morten Kjøbek Lamberts, MD, PhD, Morten Kjøbæk Lamberts, MD, PhD, Morten Lamberts |
2020-05-22 |
| A phase IIb/III trial to evaluate aviptadil in COVID-19 patients with Acute respiratory distress syndrome |
Coronavirus disease 19 infection, Respiratory distress syndrome |
aviptadil (inhaled, sarcoidosis/acute lung injury/acute respiratory distress syndrome associated COVID-19), Relief Therapeutics Holding alone |
Adrenergic receptor antagonist, VIP receptor agonist |
|
University of California Irvine |
|
US |
|
|
|
Phase 2/Phase 3 Clinical |
Planned |
1 |
|
30 |
|
2020-05-21 |
| Disguise: SARS-CoV-2 Disguise Study |
Coronavirus disease 19 infection |
biological testing alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Meshalkin Research Institute of Pathology of Circulation |
|
Russian Federation |
2020-05-07 |
2020-11-30 |
CS-COVID-19, Disguise, NCT04395794 |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
900 |
Alexander B Romanov, PhD, Denis V Losik, PhD, Dmitry N Ponomarev, PhD, Igor L Mikheenko, Nurlan A Elemesov, Vladimir V Beloborodov, Vladimir V Lomivorotov, PhD |
2020-05-22 |
| A randomized, double-blind, placebo-controlled, Phase II clinical trial designed to determine the clinical efficacy of chloroquine phosphate (CQ) in preventing coronavirus disease 2019 (COVID-19) in healthcare workers with moderate to high risk of exposure to SARS-CoV-2 |
Coronavirus disease 19 infection |
chloroquine phosphate alone |
|
|
Columbia University |
Rising Pharmaceuticals Inc |
US |
|
|
|
Phase 2 Clinical |
Status not specified |
1 |
|
350 |
|
2020-05-21 |
| ECHO: National Survey on the Lockdown of Children With Disabilities |
Coronavirus disease 19 infection, Movement disorder |
|
|
Healthy volunteers accepted, Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
University Hospital, Brest |
|
France |
2020-04-07 |
2020-05-11 |
CHRU DE BREST ECHO, ECHO, NCT04395833 |
Phase Not Applicable |
Completed |
1 |
1 Month |
2500 |
|
2020-05-22 |
| Safety and Efficacy of AT-527 in Subjects With Moderate Coronavirus Disease (COVID-19) |
Coronavirus disease 19 infection |
AT-527 alone, local supportive standard of care alone |
Hepatitis C virus NS5B polymerase inhibitor |
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Atea Pharmaceuticals Inc |
|
US |
2020-05-31 |
2020-08-31 |
AT-03A-001, NCT04396106 |
Phase 2 Clinical |
Not yet recruiting |
10 |
3 Months |
180 |
Clinical Trials Administrator |
2020-05-26 |
| The effect of omega-3 supplementation in COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia |
omega-3 (Omid persina damavand company) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sabzevar University of Medical Sciences |
|
Iran |
2020-06-04 |
|
IR.MEDSAB.REC.1399.054, IRCT20151226025699N3 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
50 |
Dr. Alireza Moslem, Saeid Doaei, Siamak Rimaz |
2020-05-22 |
| A clinical study to assess virosome-based Covid-19 vaccine candidate for the potential treatment of COVID-19 |
Coronavirus disease 19 infection |
CoV RBD219-N1 alone |
COVID19 Spike glycoprotein modulator |
|
Merck & Co Inc, Mymetics Corp |
Baylor College of Medicine, National Institute of Allergy and Infectious Diseases, Texas Children's Hospital |
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-06-01 |
| Prone Positioning and High-flow Nasal Cannula in COVID-19 Induced ARDS |
Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia |
Prone position alone, high-flow nasal cannula alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Vall D'Hebron |
|
Spain |
2020-05-01 |
2021-06-30 |
NCT04391140, PR(AG)198/2020 |
Phase Not Applicable |
Recruiting |
1 |
14 Months |
248 |
Cesar Laborda, MD, Jordi Riera, MD PhD, Judit Sacanell, MD, Marina García-de-Acilu, MD, Oriol Roca, MD PhD |
2020-05-22 |
| COVID-AKI: Urinary Biomarkers for AKI Diagnosis in Patients With SARS-CoV-2 (COVID-19) |
Coronavirus disease 19 infection, Renal injury |
urinary sampling alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital, Montpellier |
|
France |
2020-03-01 |
2020-06-30 |
COVID-AKI, NCT04393428, RECHMPL20_0294 |
Phase Not Applicable |
Recruiting |
1 |
4 Months |
100 |
Romaric Larcher, MD, PharmD, Romaric Larcher, MD, PharmD, MSc |
2020-05-22 |
| Clinical Use of Stem Cells for the Treatment of COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
allogenic umbilical cord derived-mesenchymal stem cells alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Bakirkoy Dr. Sadi Konuk Research and Training Hospital |
Istinye Universitesi, Liv Hospital (Ulus) |
Turkey |
2020-04-01 |
2020-09-30 |
BAK. SADI KONUK-ISTINYE UNI., NCT04392778 |
Phase 1/Phase 2 Clinical |
Recruiting |
2 |
6 Months |
30 |
Erdal Karaoz, Prof.Dr., Gokhan T Adas, Prof.Dr. |
2020-05-25 |
| TSUNAMI: Transfusion of Convalescent Plasma for the Early Treatment of Patients With COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
convalescent plasma alone, rescue therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Azienda Ospedaliero, Universitaria Pisana |
|
Italy |
2020-05-01 |
2020-10-30 |
NCT04393727, TSUNAMI, TSUNAMI |
Phase 2 Clinical |
Recruiting |
1 |
5 Months |
126 |
Francesco Menichetti, Marco Falcone |
2020-05-22 |
| A Randomized Study to Assess the Effect of IFN-alpha2b in Patients With COVID-19 |
Coronavirus disease 19 infection |
interferon-alpha2b (inhalant aerosol, COVID-19), The University Health Network alone |
Interferon alpha 2 ligand modulator |
|
The University Health Network |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-05-26 |
| RHUMACOVID: Drug Management of Rheumatoid Arthritis in COVID-19 Context: Impact on Therapeutic De-escalation |
Coronavirus disease 19 infection, Rheumatoid arthritis |
DMARD therapy management alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital, Brest |
|
France |
2020-04-23 |
2020-05-23 |
NCT04393233, RHUMACOVID, RHUMACOVID (29BRC20.0110) |
Phase Not Applicable |
Recruiting |
1 |
1 Month |
300 |
Dewi GUELLEC, Dewi Guellec, Valerie Devauchelle |
2020-06-01 |
| An Observational Study to Assess the Incidental Findings Suggestive of COVID-19 in Asymptomatic Patients Undergoing Nuclear Medicine Procedures in a High-Prevalence Region |
Coronavirus disease 19 infection |
131-iodine alone, 18F-FDG alone, PET/CT alone, SPECT/CT alone |
|
|
Universita degli Studi di Brescia |
|
Italy |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
77 |
|
2020-05-21 |
| Impact of an Intensified Thromboprofylaxis Protocol in COVID-19 |
Coronavirus disease 19 infection, Deep vein thrombosis, Liver failure, Renal failure |
low molecular weight heparin alone, thromboprophylaxis protocol alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Jessa Hospital |
|
Belgium |
2020-05-04 |
2020-05-15 |
JESSA-20.48, NCT04394000 |
Phase Not Applicable |
Completed |
1 |
|
72 |
|
2020-05-22 |
| Impact of Covid-19 Pandemic on Depression and Quality of Life |
Coronavirus disease 19 infection, Depression |
|
|
Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Okan University |
Yuksek İhtisas University |
Turkey |
2020-05-06 |
2020-05-18 |
56665618-204.01.07, NCT04394078 |
Phase Not Applicable |
Recruiting |
1 |
|
500 |
Begum Okudan |
2020-05-22 |
| Low Dose Radiation Therapy for Covid-19 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
low dose radiation therapy (70 cGy) alone, standard therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
All India Institute of Medical Sciences |
|
India |
2020-06-30 |
2021-06-30 |
COVID-AIIMS, NCT04394793 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
10 |
Daya Nand Sharma, MD, Randeep Guleria, MD, Supriya Mallick, MD |
2020-05-28 |
| POCUS VTE COVID: Hocus POCUS: a tool for increasing the efficiency of diagnosing venous thromboembolic disease in critically ill COVID-19 patients? |
Coronavirus disease 19 infection, Thromboembolism |
Hocus POCUS alone, point-of-care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universitair Medisch Centrum Utrecht |
|
Netherlands |
2020-05-15 |
2021-01-01 |
NL8625, POCUS VTE COVID |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
50 |
Dirk Tjwa |
2020-06-02 |
| Association of BMI with COVID-19 incidence and severity |
Coronavirus disease 19 infection |
|
|
|
Leiden University Medical Center |
|
Netherlands |
2020-03-01 |
2020-09-01 |
NL8627 |
Phase Not Applicable |
Not yet recruiting |
1 |
6 Months |
200 |
Rutger Middelburg |
2020-05-29 |
| SCOPE: Silymarin in COVID-19 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
silymarin alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cairo University |
|
Egypt |
2020-06-01 |
2020-09-30 |
CAIROU COVID-19 STUDY GROUP, NCT04394208, SCOPE |
Phase 3 Clinical |
Not yet recruiting |
1 |
4 Months |
50 |
Khaled Mohammed Korany Salem, Khaled Salem, MSc, Khaled Salem, Msc, Mostafa Alfishawy, Consultant, Mostafa Alfishawy, MD |
2020-05-20 |
| COVID 19 - What Families Think and Do? A Survey for Families Visiting the Pediatric Emergency Department |
Coronavirus disease 19 infection |
|
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
BC Children's Hospital, St Marianna University School of Medicine, University of British Columbia |
|
Japan, Europe, North America |
2020-05-22 |
|
UMIN000040451 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
500 |
Naoki Shimizu, Tomohiro Katsuta |
2020-05-23 |
| Investigation of the effect of intravenous vitamin C on definite patients with coronavirus pneumonia |
Coronavirus disease 19 infection |
Variable regimens including azithromycin , interferon beta , lopinavir + ritonavir , meropenem , vancomycin , vitamin C, Daroupakhsh Company |
HIV protease inhibitor, Penicillin binding protein inhibitor, Peptidoglycan recognition protein inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shaheed Beheshti Medical University |
|
Iran |
2020-04-08 |
|
IR.SBMU.RETECH.REC.1399.067, IRCT20200516047468N1 |
Phase 2/Phase 3 Clinical |
No longer recruiting |
1 |
|
50 |
Afshin Zarghi, Hamideh Moradi Shahr Babak |
2020-05-22 |
| Combination therapy of Favipiravir and Nafamostat Mesilate in Patients with COVID-19 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
standard treatment alone, favipiravir plus nafamostat Mesilate |
RNA polymerase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
The University of Tokyo Hospital |
|
Japan |
2020-05-01 |
|
jRCTs031200026 |
Phase 2 Clinical |
Recruiting |
1 |
|
160 |
Kyoji Moriya |
2020-05-26 |
| Amotosalen-Ultraviolet A Pathogen-Inactivated Convalescent Plasma in Addition to Best Supportive Care and Antiviral Therapy on Clinical Deterioration in Adults Presenting With Moderate to Severe COVID-19 |
Coronavirus disease 19 infection, SARS coronavirus infection |
INTERCEPT Blood System alone, convalescent plasma alone, standard of care alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
University Hospital Basel |
|
Switzerland |
2020-03-31 |
2020-06-30 |
NCT04389944, REQ-2020-00508, ME20KHANNA2 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
15 |
Andreas Buser, Prof. Dr. MD, Andreas Buser, Prof. Dr. med., Maja Weisser, Prof. Dr. med., Manuel Battegay, Prof. Dr. med., Nina Khanna, Prof. Dr. MD, Nina Khanna, Prof. Dr. med |
2020-05-20 |
| ULTRA-COVID: Ultra Low Doses of Therapy With Radiation Applicated to COVID-19 |
Coronavirus disease 19 infection, Inflammatory disease, Viral pneumonia |
Ventimask alone, nasal cannula alone, oxygen therapy alone, ultra-low-dose radiotherapy (0.8 Gy) alone, Variable regimens including Urbason , azithromycin , hydroxychloroquine (Dolquine) , lopinavir + ritonavir , low molecular weight heparin , piperacillin + tazobactam , tocilizumab |
HIV protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fundacion GenesisCare |
Hospital La Milagrosa, Hospital Vithas Valencia Consuelo |
Spain |
2020-04-21 |
2021-04-21 |
20.4.1597-GHM, NCT04394182, ULTRA-COVID |
Phase 2 Clinical |
Recruiting |
2 |
12 Months |
15 |
Elena Moreno Olmedo, MD, Escarlata López Ramírez, MD, PhD, Luis María Larrea Rabassa, MD, Manuel Pérez Fernández, MD |
2020-05-20 |
| New SARS-CoV-2 detection system |
Coronavirus disease 19 infection |
SARS-CoV-2 detection system alone |
|
|
Kawasaki Rinko General Hospital |
|
Japan |
2020-04-30 |
|
jRCT1032200025 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
50 |
Watanabe Yoshiyuki |
2020-05-26 |
| Long Term Functional Outcomes of COVID-19 Patients Treated by Rehabilitation Services viaTelehealth |
Coronavirus disease 19 infection, Viral pneumonia |
rehabilitation program alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Missouri |
|
US |
2020-05-19 |
2022-04-19 |
COVID19RECOVERY, NCT04385901 |
Phase Not Applicable |
Not yet recruiting |
1 |
23 Months |
72 |
Chelsea Harrison, DPT, Jennifer Y Stone, Jennifer Y Stone, PT, DPT, OCS |
2020-05-22 |
| Mir-Age: ABX-464 in Treating Inflammation and Preventing Acute Respiratory Failure in Patients With COVID-19 |
Coronavirus disease 19 infection, Inflammatory disease, Respiratory failure |
ABX-464 alone, standard of care alone |
Rev protein modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Abivax SA |
Bpifrance |
Europe, France |
2020-05-01 |
2021-04-30 |
ABX464-401, Mir-Age, NCT04393038 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
12 Months |
1034 |
Anais Vissian, Eric CUA, MD, Paul GINESTE |
2020-05-20 |
| Using PRP and Cord Blood in Treatment of Covid-19 |
Coronavirus disease 19 infection |
cord blood stem cells alone, platelet rich plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Aljazeera Hospital |
|
Egypt |
2020-05-25 |
2020-08-01 |
COVID -19, NCT04393415 |
Phase 2 Clinical |
Not yet recruiting |
1 |
2 Months |
100 |
Mahmoud Alalfy, PhD |
2020-05-27 |
| Efficacy of Kelofan syrup on COVID-19 |
Coronavirus disease 19 infection |
Kelofan syrup alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ardabil University of Medical Sciences |
|
Iran |
2020-05-17 |
2020-07-05 |
IR.ARUMS.REC.1399.009, IRCT20200405046960N2 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
1 Month |
60 |
Ramin Nasimi Doost Azgomi |
2020-05-21 |
| Longitudinal, COVID-19 Cohort Study |
Coronavirus disease 19 infection, Respiratory failure |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Vermont |
|
US |
2020-04-16 |
2023-05-31 |
CHRMS 16-540, NCT04393155 |
Phase Not Applicable |
Recruiting |
2 |
37 Months |
225 |
Arooj Fatima, Dale Needham, MD, PhD, Renee D Stapleton, MD, PhD, Sara S Ardren, PA |
2020-05-21 |
| COVID19IF: Imaging Feature of SARS-CoV2 Infection |
Coronavirus disease 19 infection |
|
|
|
IRCCS San Raffaele |
|
Italy |
2020-04-16 |
2020-10-01 |
COVID-19 IF, COVID19IF, NCT04394026 |
Phase Not Applicable |
Recruiting |
1 |
5 Months |
500 |
Carlo Martinenghi, MD, Francesco De Cobelli, Francesco De Cobelli, MD, Stephanie Steidler, PhD |
2020-05-20 |
| Serological Testing of Household Contacts of Confirmed Cases of COVID-19 |
Coronavirus disease 19 infection |
COVID-19 IgM/IgG test kit (Singclean) alone, serological test alone |
|
Healthy volunteers accepted, Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Universitario Dr. Jose E. Gonzalez |
|
Mexico |
2020-05-05 |
2020-06-01 |
IF20-00004, NCT04393142 |
Phase Not Applicable |
Recruiting |
1 |
|
92 |
Adrian Camacho, PhD, Adrian Camacho-Ortiz, MD, Adrian Camacho-Ortiz, PhD, Eduardo Pérez Alba, MD, Edurdo Pérez Alba, MD, Gloria Mayela Aguirre García, MD, Jaime Eugenio Espinosa Mora, MD, Laura Marina Nuzzolo Shihadeh, MD |
2020-05-21 |
| COVID_coagulation: Investigation of the predictive value of coagulation parameters for the course of disease in COVID-19 patients |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Johann Wolfgang Goethe-Universitat Frankfurt am Main |
|
Germany |
2020-04-08 |
|
20-627, COVID_coagulation, DRKS00021574 |
Phase Not Applicable |
Recruiting |
1 |
|
1000 |
Wolfgang Prof Miesbach |
2020-05-22 |
| DOCOV: Description of Ophthalmologic Injuries in Intensive Care During the SARS-CoV2 Epidemic - COVID19 |
Coronavirus disease 19 infection, Ocular injury |
Direct exam alone, Shirmer test Retinophotography alone, Slit lamp exam alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fondation Ophtalmologique Adolf De Rothschild |
|
France |
2020-04-27 |
2020-10-31 |
DOCOV, JDS_2020_13, NCT04385810 |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
100 |
Amélie YAVCHITZ, MD, Jean Michel DEVYS, MD, Sophie STEPHAN, MD |
2020-05-22 |
| LUS-COVID19: Lung Ultrasound Score in Covid-19 Infectious Disease in Critical Care |
Coronavirus disease 19 infection, Respiratory distress syndrome |
lung ultrasound (LUS) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire De Nice |
|
France |
2020-03-20 |
2020-12-31 |
20REAMEDCOVID03, LUS-COVID19, NCT04393402 |
Phase Not Applicable |
Recruiting |
1 |
9 Months |
14 |
Jean DELLAMONICA, Jean DELLAMONICA, MD, PhD, Romain LOMBARDI |
2020-05-21 |
| Trial of Imatinib for Hospitalized Adults With COVID-19 |
Coronavirus disease 19 infection |
imatinib alone |
Abl tyrosine kinase inhibitor, Bcr protein inhibitor, Kit tyrosine kinase inhibitor, PDGF receptor antagonist, Signal transduction inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Maryland |
|
US |
2020-05-20 |
2023-06-01 |
2038GCCC, NCT04394416 |
Phase 3 Clinical |
Not yet recruiting |
1 |
36 Months |
204 |
Ashkan Emadi, MD, PhD, Monica Estrada |
2020-05-21 |
| CORMOR: Blood Ozonization in Patients With SARS-CoV-2 Respiratory Failure |
Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure, Respiratory insufficiency, Viral pneumonia |
Blood Ozonization alone, Variable regimens including Hydroxychloroquine , darunavir + cobicistat (fixed dose, HIV infection), Janssen R&D/ Gilead , lopinavir + ritonavir |
Cytochrome P450 3 inhibitor, HIV protease inhibitor, HIV-1 protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Azienda Universitaria Integrata di Udine |
Azienda Ospedaliera Ordine Mauriziano di Torino, Azienda Sanitaria Locale di Vercelli, Celio Military Hospital, Fondazione Toscana Gabriele Monasterio, Ospedale Civile S. Liberatore di Atri, Ospedale Civile di Lucca, Ospedale di Siracusa, University of Siena |
Italy |
2020-04-08 |
2020-10-08 |
CIG: Z7C2CA5837, CORMOR, NCT04388514 |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
90 |
Amato De Monte, Amato De Monte, MD, Carlo Tascini, MD, Emanuela Sozio, MD |
2020-05-22 |
| PROVENT-COVID: Accelerated Prone Position Ventilation of Patients With COVID-19 |
Coronavirus disease 19 infection |
Prone position ventilation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Nordsjaellands Hospital |
|
Denmark |
2020-05-11 |
2020-12-31 |
H-20027361, NCT04384900, PROVENT-COVID |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
150 |
Morten H Bestle, MD, PhD, Morten H Bestle, MD,PhD, Theis S Itenov, MD, PhD, Theis S Itenov, MD,PhD |
2020-05-21 |
| COVID-PRONE: Prone Positioning for Patients on General Medical Wards With COVID19 |
Coronavirus disease 19 infection |
Prone positioning alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
St Michaels Hospital |
Sinai Health System, Sunnybrook Health Sciences Centre, The University Health Network, Toronto General Hospital |
Canada |
2020-05-15 |
2020-12-11 |
2020-1, COVID-PRONE, NCT04383613 |
Phase Not Applicable |
Recruiting |
5 |
6 Months |
350 |
Amol Verma, MD, MPhil, Fahad Razak, MD, MSc, Michael Fralick, MD, PhD |
2020-05-22 |
| CoVInnate: Role of Inflammasomes in COVID-19 Disease |
Coronavirus disease 19 infection |
DNA analysis alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire De Nice |
|
France |
2020-05-11 |
2021-06-12 |
20-PP-07, CoVInnate, NCT04385017 |
Phase Not Applicable |
Recruiting |
2 |
13 Months |
40 |
COURJON JOHAN, PH, COURJON JOHAN, Ph, COURJON Johan, COURJON Johan, Ph, CUA ERIC, PH, Cua Eric, Ph, ROBERT Alexandre, ROBERT Alexandre, Ph |
2020-06-02 |
| Seroprevalence of SARS CoV 2 Antibodies in Previously Undiagnosed Healthcare Workers |
Coronavirus disease 19 infection |
Serologic testing alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Mayo Clinic Foundation |
|
US |
2020-05-06 |
2020-06-12 |
20-004054, NCT04383587 |
Phase Not Applicable |
Recruiting |
1 |
1 Month |
300 |
Mark Parkulo, MD |
2020-05-21 |
| COVIDVIT: Do Vitamin D Levels Really Correlate With Disease Severity in COVID-19 Patients? |
Coronavirus disease 19 infection |
vitamin D alone |
|
|
Bursa City Hospital |
|
Turkey |
2020-05-01 |
2020-06-30 |
1, COVIDVIT, NCT04394390 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
100 |
Taner Dandinoğlu |
2020-05-22 |
| Convalescent Plasma and Placebo for the Treatment of COVID-19 Severe Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
Convalescent SARS COVID-19 plasma alone, standard care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Italiano de Buenos Aires |
|
Argentina |
2020-05-15 |
2020-08-20 |
5565, NCT04383535 |
Phase Not Applicable |
Not yet recruiting |
7 |
3 Months |
333 |
Claudia Salgueira, Esteban Nannini, Fernando Palizas, Florencia Otermin, Francisco Klein, Gustavo Lopardo, Javier Altclas, Javier Sarro, Karina Rainiero, Laura Barcelona, Liliana Sarro, Marcelo Losso, Mariangeles Fenes, Matias Lahitte, Nadia Ahmed, Nora A Fuentes, MD, Pablo Gutierrez, Ricardo Valentini, Santiago Ramirez Borga, Ventura Simonovich, MD, Waldo H Belloso, PhD |
2020-05-22 |
| SINUS WASH: Pilot Study in Adults Testing Positive for COVID-19 |
Coronavirus disease 19 infection |
Betadine alone, Umotif app alone, Videne alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hampshire Hospitals NHS Foundation Trust |
|
UK |
2020-05-31 |
2020-08-31 |
2020-001721-31, NCT04393792, SINUS WASH, SPON-AK-0420 |
Phase 2 Clinical |
Recruiting |
1 |
3 Months |
40 |
Afroze Khan, MBBS MRCS, Chief Investigator, Matthew Dryden |
2020-05-22 |