Last updated: Jun 06, 2020 - 02:00 BST

Title Indication Intervention Actions PatientSelection Sponsor Collaborator Country StartDate EndDate Identifiers Phase Recruitment Status Sites Trial Duration Enrollment Count Contacts LastChanged
Hydroxychloroquine to Prevent SARS-CoV-2 Infection Coronavirus disease 19 infection hydroxychloroquine alone, standard personal protection measure alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidad Peruana Cayetano Heredia Peru 2020-06-30 2020-10-31 202087, 20923, NCT04414241 Phase 3 Clinical Not yet recruiting 0 4 Months 320 Aldo Lucchetti, MD, Alejandro Llanos, MD, PhD, Alonso Soto, MD, MSc, PhD, Alvaro Schwalb, MD, César Ugarte-Gil, MD, MSc, PhD, Eduardo Gotuzzo, MD, Fernando Mejia, MD, MSc, Manuel Espinoza, MD, Max Grogl, PhD, Patricia García, MD, MPH, PhD, Rosio Guerra, MD, MPH 2020-06-05
COVID19 Clinical Predictors and Outcome Coronavirus disease 19 infection, Respiratory failure Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) St George's University Hospitals NHS Foundation Trust St Georges University of London UK 2020-06-15 2022-04-30 2020.0115, NCT04416347 Phase Not Applicable Not yet recruiting 0 22 Months 800 Timothy D Planche, Dr. 2020-06-05
PROTECT-COVID-19: Conestat Alfa in the Prevention of Severe SARS-CoV-2 Infection in Hospitalized Patients With COVID-19 Acute lung injury, Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia conestat alfa alone, standard of care alone Complement C1s subcomponent inhibitor, Kallikrein modulator, Mannan-binding lectin serine protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Pharming Group NV, University Hospital Basel Pharming Technologies BV Switzerland 2020-06-30 2021-07-31 2020-01252, ME20OSTHOFF3, NCT04414631, PROTECT-COVID-19 Phase 2 Clinical Not yet recruiting 0 13 Months 120 Marten Trendelenburg, Prof. med, Michael Osthoff, PD Dr. med, Michael Osthoff, PD Dr. med., Parham Sendi, Prof. med., Stephan Moser, MD 2020-06-05
ERSul study: Sulodexide in the treatment of COVID-19 Coronavirus disease 19 infection conventional treatment alone, sulodexide alone Heparin agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) CLINEDEM, Mexico Mexico 2020-04-15 2020-11-30 ERSul study, ISRCTN59048638 Phase 4 Clinical Not yet recruiting 1 7 Months 600 Dr Alejandro Jose Gonzalez Ochoa 2020-06-05
COOPCOVID-19: Treatment of Patients With COVID-19 With Convalescent Plasma Coronavirus disease 19 infection convalescent plasma alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo Faculdade de Ciências Aplicadas (FCA) da UNICAMP, Fundacao Hemocentro de Ribeirao Preto, Hospital Of Syrian Lebanese Itatiba S/C Ltd, Ministry of Science and Technology, Brazil, Sociedade Beneficente Israelita Brasileira Hospital Albert Einsten Brazil 2020-06-01 2022-05-22 COOP-COVID-19-MCTIC, COOPCOVID-19, NCT04415086 Phase 2 Clinical Not yet recruiting 1 23 Months 120 2020-06-05
ReCOVER: Evaluation of a Remote Monitoring Smartphone Application and Care Model of COVID-19 Patients in the Community (ReCOVER) Coronavirus disease 19 infection TCC-COVID mHealth solution alone, standard of care treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of New South Wales Health South Eastern Sydney Local Health District, The George Institute for International Health Australia 2020-05-20 2021-05-19 NCT04399109, PID00770, ReCOVER Phase Not Applicable Recruiting 3 12 Months 2000 Benjamin Kwan, Clarissa Susanto, Dr Sze-Yuan Ooi, Jeffrey Post, Kristen Overton, Nigel Lovell, Pamela Konecny, Richard Sullivan, Sze-Yuan Ooi 2020-06-05
Short-term Physical Function Outcomes in Severe COVID-19 Patients Admitted to ICU for Invasive Mechanical Ventilation Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal Spain 2020-05-15 2020-11-15 165/20, NCT04400461 Phase Not Applicable Recruiting 2 6 Months 50 Irene Lázaro Navarro, PT,MSc,PhD, Luís López-Gónzalez, PT, MSc, Maria Natividad Seisdedos-Nunez, PT, MSc, María-Natividad Seisdedos-Nunez, PT, MSc 2020-06-05
COVRTE-19: Low Dose Pulmonary Irradiation in Patients With COVID-19 Infection of Bad Prognosis Coronavirus disease 19 infection, Respiratory disease, Viral pneumonia low dose lung radiotherapy alone, standard support therapy alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundacion Hospital Provincial de Castellon Spain 2020-06-01 2021-03-31 COVRTE-19, FHPCS-20-001, NCT04414293 Phase 2 Clinical Not yet recruiting 1 10 Months 41 Carlos Ferrer Albiach, MD, FRANCISCO GARCIA PINON, MSc, Francisco Garcia Piñón, MSc 2020-06-05
Oral Favipiravir for Patients with Delayed SARS-Cov-2 viral RNA Clearance Coronavirus disease 19 infection, Viral infection favipiravir alone RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Wuhan Huoshenshan Hospital China 2020-03-18 2020-05-12 ChiCTR2000033491 Phase 4 Clinical No longer recruiting 1 1 Month 9 Jiqiu Wen 2020-06-05
A Phase II Study to Evaluate Axatilimab for Hospitalized Patients With Respiratory Involvement Secondary to COVID-19 Coronavirus disease 19 infection, Respiratory disease Standard of care alone, axatilimab alone CSF-1 antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Syndax Pharmaceuticals Inc US 2020-05-30 2020-11-15 NCT04415073, SNDX-6352-0505 Phase 2 Clinical Recruiting 2 5 Months 186 Magdalena Mamczur-Madry, RN, BSN, MS, ACRP-CP, Michael S. Gordon, M.D., Shani Hilliard, Sue Fischer 2020-06-05
ESHAZ: Hydroxychloroquine, Azithromycin and Zinc for the treatment of SARS-Cov2 infection in Senegal. COVID-19 Coronavirus disease 19 infection azithromycin plus hydroxychloroquine Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cheikh Anta Diop University Senegal 2020-06-01 ESHAZ, PACTR202005622389003 Phase 3 Clinical Not yet recruiting 1 384 Cheikh T. NDOUR, Roger TINE 2020-06-05
RESOLUTION: Study of LAU-7b for the Treatment of COVID-19 Disease in Adults Coronavirus disease 19 infection, Lung inflammation, Respiratory distress syndrome fenretinide (pulmonary Pseudomonas aeruginosa infections in cystic fibrosis), McGill University/Laurent Pharmaceuticals alone, standard-of-care alone Nuclear factor kappa B gene modulator Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Laurent Pharmaceuticals Canada, US 2020-06-08 2021-01-15 LAU-20-01, NCT04417257, RESOLUTION Phase 2 Clinical Not yet recruiting 2 7 Months 300 Alexandria Flannery, Jean-Marie Houle, PhD, Mylene Roy, Radu Pislariu, MD, Ramy Saleh, MD, Todd Campbell Lee, MD 2020-06-05
ECHO-COVID: Echocardiography in Critically-ill Patients With COVID-19 Pneumonia Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia echocardiography alone Hôpital Ambroise Paré France 2020-05-12 2020-09-30 ECHO-COVID, NCT04414410, REDCAP19 Phase Not Applicable Recruiting 1 4 Months 1500 Antoine Vieillard-Baron, MD, PhD 2020-06-05
I-TOMIC: Tofacitinib for Treatment of Moderate COVID-19 Coronavirus disease 19 infection, Viral pneumonia standard of care alone, tofacitinib alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Yale University US 2020-06-30 2021-03-31 2000027848, I-TOMIC, NCT04415151 Phase 2b Clinical Not yet recruiting 1 9 Months 60 Hyung Chun, MD, Kelly Borges, MS, BS 2020-06-05
Extracellular Water in Covid-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia whole body bioimpedence system (NİCaS) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gaziosmanpasa Taksim Research and Education Hospital Turkey 2020-07-05 2021-02-20 76, NCT04416009 Phase Not Applicable Recruiting 1 7 Months 52 SİBEL BEKTAŞ, aygen türkmen, Prof.MD, zuhal çavuş, MD 2020-06-05
AntiCoV-HB: COVID-19: Seroprevalence Study of Anti SRAS-CoV-2 Antibodies in GHT Employees in Haute Bretagne Coronavirus disease 19 infection ELISA assays alone, LIPS assays alone, NG-Biotech test alone, S-FLOW assays alone, blood test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rennes University Hospital Fonds Nominoë France 2020-05-29 2020-11-10 35RC20-9716, AntiCoV-HB, NCT04416308 Phase Not Applicable Recruiting 1 5 Months 13000 Agnès GAZZOLA, CHRISTOPHE PARIS, MD, Christophe PARIS, MD, RONAN GARLANTEZEC, MD, Ronan GARLANTEZEC, MD 2020-06-05
HoCoPsy: Characteristics of the Patients Hospitalized With Involuntary Commitment Procedure, in the Context COVID-19 Coronavirus disease 19 infection, Psychiatric disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Montpellier France 2020-05-01 2020-06-30 HoCoPsy, NCT04417374, RECHMPL20_0320 Phase Not Applicable No longer recruiting 1 2 Months 94 Emilie Olie, MD PhD 2020-06-05
COVILLE2: Part 2 on the Study Prevalence of SARS -Cov2 Carriage in Asymptomatic and Mildly-symptomatic Children Coronavirus disease 19 infection RT-PCR alone, Sars-Cov2 serology alone Healthy volunteers accepted, Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) Centre Hospitalier Intercommunal Creteil ACTIV, France, GFRUP, GPIP (FR) 2020-06-07 2020-11-15 COVILLE2, COVILLE2, NCT04416893 Phase Not Applicable Not yet recruiting 0 5 Months 630 2020-06-05
Who Benefits More? Optimizing Mindfulness Based Interventions for Improved Psychological Outcomes Acute stress disorder, Coronavirus disease 19 infection, Sleep disorder mindfulness based intervention alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National University of Singapore Brahm Centre Singapore 2019-09-20 2022-06-30 NCT04417153, S-19-176 Phase Not Applicable Recruiting 1 33 Months 1000 Francesca Perini, PhD, Julian Lim, PhD 2020-06-05
A phase II pivot study of LY-CoV555 in patients with COVID-19 infection Coronavirus disease 19 infection LY-CoV555 alone COVID19 Spike glycoprotein modulator Eli Lilly & Co Phase 2 Clinical Planned 0 2020-06-05
Melatonin Immune Boost COVID 19 Study Coronavirus disease 19 infection melatonin alone Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute Of Medical Sciences, Rishikesh India 2020-06-15 CTRI/2020/06/025613 Phase 4 Clinical Not yet recruiting 0 200 Rohit Walia 2020-06-05
COVIM: COVID-19 Epidemic and Patients With Myeloproliferative Neoplasias Coronavirus disease 19 infection, Myelofibrosis, Myeloproliferative disorder, Polycythemia vera, Thrombocythemia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) French Innovative Leukemia Organisation France 2020-06-15 2020-12-31 COVIM, COVIM, NCT04416438 Phase Not Applicable Not yet recruiting 0 6 Months 50 Jean-Jacques KILADJIAN, Pr, Laurence LEGROS, Dr, Valerie ROLLAND 2020-06-05
A trial to evaluate replication-competent VSV chimeric virus-based vaccine (COVID-19), IAVI/Batavia Biosciences/Merck & Co Inc for the prevention of SARS-CoV-2 infection Coronavirus disease 19 infection replication-competent VSV chimeric virus-based vaccine (COVID-19), IAVI/Batavia Biosciences/Merck & Co Inc alone COVID19 Spike glycoprotein modulator International AIDS Vaccine Initiative Merck & Co Inc Phase Not Applicable Planned 0 2020-06-05
An observational, retropsective, single-center study to evaluate the short-term effect of risk-adapted treatment strategy on patients with COVID-19 Coronavirus disease 19 infection Chinese Academy of Sciences, University of Science & Technology of China Phase Not Applicable Status not specified 0 55 2020-06-05
RE-HCP2 COVID study: A study to determine relative efficacy of hydroxychloroquine prophylaxis to healthcare-professionals for Covid-19 mitigation Coronavirus disease 19 infection hydroxychloroquine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute Of Medical Sciences, Rishikesh India 2020-06-12 CTRI/2020/06/025593, RE-HCP2 COVID study Phase Not Applicable Not yet recruiting 0 3000 Prasan Kumar Panda 2020-06-05
CovILD: Development of Interstitial Lung Disease (ILD) in Patients With Severe SARS-CoV-2 Infection (COVID-19) Coronavirus disease 19 infection, Interstitial lung disease Blood sampling alone, HRCT alone, Spirometry alone, echocardiography alone, plethysmography alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Medizinische Universität Innsbruck Austria 2020-04-29 2022-04-28 20200429-2255, CovILD, NCT04416100 Phase Not Applicable Recruiting 1 24 Months 130 Ivan Tancevski, Doz. Dr., Judith Löffler-Ragg, Prof. Dr. 2020-06-05
Quality of Life and Patient-centered Outcomes After UCI Admission for COVID-19 Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Porto Centro Hospitalar Lisboa Ocidental, Centro Hospitalar do Porto, Universidade Do Algarve Portugal 2020-06-15 2022-10-01 NCT04416464, QOL_ICU_COVID Phase Not Applicable Not yet recruiting 4 27 Months 230 António Sarmento, Cristina Granja, Prof., Irene Aragão, Isabel J Pereira, Lurdes Santos, Luís Filipe Azevedo, Prof., Mariana MS Santos, MSc. 2020-06-05
COVID&PREG: COVID-19 and Pregnancy Outcomes Coronavirus disease 19 infection RT PCR alone Female, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Universidade Nova De Lisboa Portugal 2020-03-22 2023-12-31 COVID&PREG, COVID&PREG, NCT04416373 Phase Not Applicable Recruiting 1 45 Months 300 Alexandra Queirós, MD, Alexandra S Queiros, MD, Ana M Campos, PhD,MD, Maria J Alves, MD, Nadia Charepe, MD,MSc, Nadia Charepe, MSc, MD, Teresa Ventura, PhD,MD 2020-06-05
Clinical Characteristics of Critically Ill Patients With COVID-19 Coronavirus disease 19 infection File Scanning alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Nevsehir Public Hospital Turkey 2020-06-30 2020-07-25 2020-05-13T12_44_51, NCT04413435 Phase Not Applicable Recruiting 1 105 Betül Kozanhan, Dr, Mehmet Akif Yaza, Yasin Tire, Dr 2020-06-05
STOIC: Steroids in COVID Study Coronavirus disease 19 infection, Respiratory disease budesonide alone, ciclesonide alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Oxford 2020-05-30 2020-11-30 NCT04416399, STOIC, STOIC STUDY Phase 2 Clinical Not yet recruiting 0 6 Months 478 Mona Bafadhel, MBBS, PhD 2020-06-05
A phase II proof of concept trial to assess efficacy of LY-CoV555 in COVID-19 vulnerable populations Coronavirus disease 19 infection LY-CoV555 alone COVID19 Spike glycoprotein modulator Eli Lilly & Co Phase 2 Clinical Planned 0 2020-06-05
Ruxolitinib in the Treatment of Covid-19 Coronavirus disease 19 infection ruxolitinib (oral, myeloproliferative disorders), Incyte/Novartis alone Jak1 tyrosine kinase inhibitor, Jak2 tyrosine kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Clinica Zabala Novartis AG Argentina 2020-06-01 2020-09-15 CZABALA, NCT04414098 Phase 2 Clinical Not yet recruiting 1 3 Months 100 Joaquin Castro, MD, Marcelo Iastrebner, MD 2020-06-05
COVIDOCRECHE: Multicenter, Interventional Study of SARS-CoV-2 Infection and Transmission Coronavirus disease 19 infection Nasopharyngeal swab test alone, Rapid detection test alone, Stool collection alone Healthy volunteers accepted, Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-06-02 2021-06-02 2020-A01540-39, APHP200587, COVIDOCRECHE, NCT04413968 Phase Not Applicable Not yet recruiting 1 12 Months 600 Eric LACHASSINNE, MD, Mohammed RAHAOUI, PM 2020-06-05
COVELEC: Protein Electrophoresis as a Tool for Complications Prediction in COVID-19 Hospitalized Patients Coronavirus disease 19 infection, Inflammatory disease serum protein electrophoresis alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Clinique de l'Estrée France 2020-06-15 2021-06-30 2020-A01376-33, COVELEC, COVELEC, NCT04414059 Phase Not Applicable Not yet recruiting 1 12 Months 155 Johanna MIMOUNI, Shahnaz KLOUCHE, Stephane DI MASCIO, MD, Stéphane DI MASCIO, MD 2020-06-05
ICOPE: Implementation of the Integrated Care of Older People App and ICOPE Monitor in Primary Care Coronavirus disease 19 infection Healthy volunteers accepted, Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Liege Centre Hospitalier Universitaire de Toulouse Belgium 2020-10-31 2021-11-30 GERULIEGE/SG/DSR/ICOPE, ICOPE, NCT04413877 Phase Not Applicable Not yet recruiting 0 13 Months 600 Dolores Sanchez-Rodriguez, MD PhD, Sophie Gillain, MD PhD 2020-06-05
A clinical trial to evaluate safety and efficacy of polyherbal capsule Astha-15 used as an add on therapy with standard care of therapy as an immunity booster in the suspected and COVID-19 diagnosed patients Coronavirus disease 19 infection Astha-15 alone, standard care of therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Dalmia Centre For Research & Development India 2020-06-08 CTRI/2020/06/025590, DAL/CT/001/AST/2020 Phase 3 Clinical Not yet recruiting 4 120 Dr A Gopal Rao, Dr Amulya Bhati, Dr Prastita P Kshirsagar, Dr Vinod Kumar, Mukesh Kumar 2020-06-05
Comparison of two different laryngoscopes using COVID barrier box Coronavirus disease 19 infection, General anesthesia Ambu King video laryngoscope alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Medical Sciences Bhubaneswar India 2020-06-15 CTRI/2020/06/025589 Phase Not Applicable Not yet recruiting 1 60 Sangeeta Sahoo 2020-06-05
Data of patients with Corona virus disease admitted to the ICU at P.D. Hinduja Hospital, Mumbai Coronavirus disease 19 infection Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) P. D. Hinduja hospital and medical research centre India 2020-06-08 CTRI/2020/06/025588 Phase Not Applicable Not yet recruiting 1 400 Dr Alex Fonseca, Dr Farhad N Kapadia 2020-06-05
SEV-Covid Trial: Safety and efficacy of antiviral combination therapy in symptomatic patients of Covid-19 infection - a randomized, control trial Coronavirus disease 19 infection Standard Treatment(STns) alone, Standard Treatment(STs) alone, oseltamivir alone Exo-alpha sialidase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences India 2020-06-15 CTRI/2020/06/025575, SEV-Covid Trial Phase 3 Clinical Not yet recruiting 1 175 Prasan Kumar Panda 2020-06-05
Effect of Ayurvedic medicine in the Prophylaxis for COVID-19 of AYUSH healthcare workers , Dept of AYUSH, TS and CCRAS- NIIMH, Hyderabad Coronavirus disease 19 infection Ayush 64 alone, Chavanprash alone, Samshamani vati alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Aayush Healthcare India 2020-06-15 CTRI/2020/06/025561 Phase 2/Phase 3 Clinical Not yet recruiting 1 500 Dr Srikanth Babu Perugu 2020-06-05
ATENEA-Co-300: ATENEA-Co-300 study Coronavirus disease 19 infection CIGB-300 alone, treatment established in the national action protocol alone Casein kinase II inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Center for Genetic Engineering and Biotechnology Ministerio de Salud Publica Cuba 2020-06-01 ATENEA-Co-300, IG/CIGB300I/CV/2001, RPCEC00000317 Phase 1/Phase 2 Clinical Not yet recruiting 1 20 Idania Baladron Castrillo, Leticia del Rosario Cruz, Silvio Perea Rodriguez 2020-06-04
A clinical trial of InspectIR portable breathalyzer for the detection of COVID-19 infection Coronavirus disease 19 infection InspectIR portable breathalyzer alone Inspectir Systems LLC US 2020-05-27 Phase Not Applicable Recruiting 1 Dr. Gustavo Day 2020-06-05
TRAiN: Rapid-Cycle Re-Implementation of Training Facilities in Norway Coronavirus disease 19 infection access to training facility alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) The Norwegian Directorate for Health and Social Affairs University of Oslo Norway 2020-05-20 2022-05-19 NCT04406909, REK 143984, TRAiN Phase Not Applicable Not yet recruiting 1 24 Months 8564 Lise Helsingen, MD, Magnus Løberg, MD PhD, Mette Kalager, MD PhD, Michael Bretthauer, MD PhD 2020-06-05
Acute and chronic cardiovascular and respiratory changes in COVID-19 hospitalized patients and the effect of physical rehabilitation supervised by telecommunication Coronavirus disease 19 infection physical rehabilitation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundação Universidade Federal De São Carlos, Universidade Estadual Paulista (UNESP) Brazil 2020-07-01 32134720.4.1001.5398, 4.039.688, RBR-9y32yy, U1111-1252-5187 Phase Not Applicable Not yet recruiting 1 100 Alessandro Domingues Heubel, Ariane Aparecida Viana, Emmanuel Gomes Ciolac, Renata Gonçalves Mendes 2020-06-05
A open-labelled study to assess the safety and efficacy of a clinical course of oral apabetalone in hospitalized subjects with 2019-nCoV infection Coronavirus disease 19 infection apabetalone alone APOA1 gene stimulator, Angiotensin converting enzyme 2 inhibitor, Bromodomain containing protein 2 inhibitor, Bromodomain containing protein 4 inhibitor Resverlogix Corp Phase Not Applicable Planned 0 2020-06-04
A phase Ib, proof-of-concept, randomized, double-blind, placebo-controlled clinical study to evaluate the potential of TRV-027 to treat acute lung injury contributing to acute respiratory distress syndrome (ARDS) in COVID-19 patients Acute lung injury, Adult respiratory distress syndrome, Coronavirus disease 19 infection TRV-027 alone Angiotensin II AT-1 receptor antagonist, Beta-arrestin stimulator Aged Adults (65-79 yrs), Elderly Adults (80 and over) British Heart Foundation, Imperial College London Trevena Inc Phase 1b Clinical Planned 0 60 2020-06-04
Using Homeopathic Combinations for Prevention and Treatment of Viral Fevers including COVID 19 Coronavirus disease 19 infection, Fever, Viral infection Variable regimens including Aconite 30 , Allium Cepa 30 , Arsenic Album 30 , Echinacia 0 , Eupatorium 30 , Gelsmium 30 , Influenzum 30 , Thuja 0  Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sanjay Gandhi Postgraduate Institute of Medical Sciences 2020-06-18 CTRI/2020/06/025530 Phase Not Applicable Not yet recruiting 0 10000 Dr AK Gupta, Dr Anil Agarwal, Dr Piyush Gupta 2020-06-05
SCENARIO: Prevalence of SARS-CoV-2 (COVID-19) in pregnancy and at delivery in Franconia, Germany Coronavirus disease 19 infection, Pregnancy disorder Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitatsklinikum Erlangen Germany 2020-06-02 185_20B, DRKS00022088, SCENARIO Phase Not Applicable Recruiting 1 2550 Alexander Hein 2020-06-05
Clinical trial on Immunity and antiviral for quarantine patients of COVID-19 Coronavirus disease 19 infection Amrta Karuna Syrup alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Vopec Pharmaceuticals Pvt Ltd India 2020-06-01 CT/Vopec/Amrta Karuna /2020 version 1.0, CTRI/2020/06/025527 Phase 4 Clinical Not yet recruiting 1 30 Dr Dinesh 2020-06-05
Guduchi Ghanavati as a prophylactic measure among population at high risk to SARS-CoV-2 exposure Coronavirus disease 19 infection Guduchi Ghanavati   alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) GUJARAT AYURVED UNIVERSITY India 2020-06-09 CTRI/2020/06/025525 Phase Not Applicable Not yet recruiting 3 20000 Anup Thakar, Bharat Kalsariya, Harshit Shah, Kalpesh Panara, Naresh Jain, Sweety Ruparel 2020-06-05
Can the Prediction Market Improve Predictions of COVID-19? Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National University of Singapore Singapore 2020-05-15 2020-05-17 NCT04410692, SG-COVID Phase Not Applicable Completed 1 560 Teck Ho, PhD 2020-06-05
To observe the impact of Ayurveda Kwath in Healthy and Suspected persons for COVID-19 Coronavirus disease 19 infection Ayurveda Kwath alone Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Dr.S R.Rajasthan Ayurved University Jodhpur India 2020-06-10 CTRI/2020/06/025526 Phase Not Applicable Not yet recruiting 1 500 Prof Govind Sahay Shukla 2020-06-05
ACCESS: A clinical study of real-world monitoring of COVID-19 Vaccines Coronavirus disease 19 infection European Medicines Agency, Universiteit Utrecht Europe ACCESS Phase Not Applicable Status not specified 0 2020-06-04
A phase II, open-label, non-randomized, clinical trial of the safety and efficacy of the CovidCare app to support self-monitoring for COVID-19 symptoms in self-isolation and to determine the impacts on mental health Anxiety disorder, Coronavirus disease 19 infection, Depression CovidCare app alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Melbourne Australia 2020-06-08 ACTRN12620000640909, U1111-1251-7257 Phase 2 Clinical Not yet recruiting 1 200 A/Prof Victoria Palmer, Ms Maria Potiriadis 2020-06-05
TTCOV19: Timing of Tracheotomy in Covid-19 Patients Coronavirus disease 19 infection Early tracheotomy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sahlgrenska University Hospital Sweden 2020-06-01 2021-02-01 HBERGQUIST, NCT04412356, TTCOV19 Phase Not Applicable Not yet recruiting 1 8 Months 180 Henrik Bergquist, Assoc Prof, Måns Eeg-Olofsson, Assoc Prof 2020-06-05
A phase III trial of bemcentinib for COVID-19 Coronavirus disease 19 infection bemcentinib alone Axl tyrosine kinase receptor inhibitor BerGenBio AS UK Phase 3 Clinical Planned 1 2020-06-04
XoGloCoV2: To study the treatment of COVID-19 with severe viral pneumonia by using purified stem cell exosomes Coronavirus disease 19 infection, Lymphocytopenia, Pulmonary fibrosis, Respiratory failure, Viral pneumonia XoGlo alone Kimera Labs University Hospital Ulm Germany 2020-04-26 2020-12-31 2020-002326-90, 89081, ISRCTN33578935, XoGloCoV2 Phase 2 Clinical Recruiting 1 8 Months 64 Prof Marion Schneider 2020-06-05
A compassionate use program of Organicell Flow for the treatment of COVID-19 infection Coronavirus disease 19 infection Organicell Flow alone Organicell Regenerative Medicine US Phase Not Applicable Status not specified 1 2020-06-04
Efficacy and Safety of Hydroxychloroquine and Favipiravir in the Treatment of Mild to Moderate COVID-19 Coronavirus disease 19 infection, Viral pneumonia favipiravir alone, Variable regimens including azithromycin , favipiravir , hydroxychloroquine RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ministry of Health of Turkey Ankara City Hospital Bilkent, Ankara Training and Research Hospital, Ankara University, Ege University Hospital (Application and Research Center), Hacettepe University, Istanbul University Faculty of Medicine, Istanbul University-Cerrahpasa, Kayseri City Hospital, Kocaeli Derince Education and Research hospital, SB Istanbul Education and Research Hospital, Sultan Abdulhamid Han Training and Research Hospital, Tepecik Training and Research Hospital, Umraniye education and research hospital Turkey 2020-05-08 2020-07-30 COVID-19-FAV, NCT04411433 Phase 3 Clinical Recruiting 1 2 Months 1000 Prof. Ates KARA, MD, Prof. Ateş KARA, MD, Prof. Ateş Kara, MD 2020-06-05
Novel COVID-19: A National Analysis Coronavirus disease 19 infection, Respiratory tract infection, Viral pneumonia Assiut University Egypt 2020-05-20 2020-06-30 NCT04413045, NOVEL COVID-19 PREVALENCE Phase Not Applicable Recruiting 1 1 Month 50 Mohamed F. Mostafa, MD 2020-06-05
COVID-19_LF: Clinical Assessment of Oral Lactoferrin as a Safe Antiviral and Immunoregulatory in Treating COVID-19 Disease Coronavirus disease 19 infection bovine apolactoferrin alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Research Center Patent Office Egyptian Military Medical Services Egypt 2020-06-01 2020-09-30 COVID-19_LF, COVID-19_LF, NCT04412395 Phase 2 Clinical Not yet recruiting 4 4 Months 516 Bassim Mohamed, PhD, Christine Gindy, B Pharm, Khaled Prince, B Pharm, Marawan Abdelbaset, PhD, Osama Azmy, MD, Rehab Hegazy, PhD, Rehab Ragab Hegazy, Wafaa Abdel Aal, MD 2020-06-05
A Study of LY-3819253 (LY-CoV555) in Participants Hospitalized for COVID-19 Coronavirus disease 19 infection LY-CoV555 alone COVID19 Spike glycoprotein modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Eli Lilly & Co AbCellera Biologics Inc US 2020-05-28 2020-08-23 17823, J2W-MC-PYAA, NCT04411628 Phase 1 Clinical Recruiting 6 2 Months 40 Mark J Mulligan, Michael L Dougan, Nadine G Rouphael, Pauline K Park, Peter Chen 2020-06-05
COVID-19 HUSO: Clinical trial, randomized, open-label, to evaluate the efficacy of high-dose vitamin D in patients with COVID-19 pneumonia Coronavirus disease 19 infection, Viral pneumonia vitamin D (Thorens) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Universitario Severo Ochoa Spain 2020-05-28 01052020, 2020-002312-43, COVID-19 HUSO Phase 3 Clinical Recruiting 1 82 Miguel Cervero 2020-06-04
CovidCare - 1: Surveillance and care for confirmed and suspected patients with COVID-19 in general practice: an observational study Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Heidelberg AOK Baden-Württemberg Germany 2020-05-05 CovidCare - 1, DRKS00022054, S-266/2020 Phase Not Applicable Recruiting 1 400 Frank Peters-Klimm, Markus Qreini 2020-06-05
BATS: Best available treatment study for inflammatory conditions associated with COVID-19 Coronavirus disease 19 infection, Inflammatory disease Imperial College London UK 2020-05-08 2022-05-31 BATS, IRAS 284825, ISRCTN69546370 Phase Not Applicable Not yet recruiting 1 24 Months 1800 Prof Levin 2020-06-05
ImmunoCorona: Evaluation of the synergistic effect of sequential administration of two immunostimulant products: Immuno-1 and Immuno-2 for the stimulation of the immune response in older adults. Exploratory study Coronavirus disease 19 infection Immuno-1 plus Immuno-2 Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Finlay Institute National Center for Biopreparations (BIOCEN) Cuba 2020-05-19 ImmunoCorona, RPCEC00000315 Phase 2 Clinical Recruiting 1 60 Dagmar Garcia Rivera, Rinaldo Puga Gomez 2020-06-04
COVIDIAB-13: Covid-19 and Diabetes in West of Algeria Coronavirus disease 19 infection, Diabetes mellitus, Lung embolism glucocorticoid therapy alone, oxygen therapy alone, Variable regimens including azithromycin , hydroxychloroquine , insulin , lopinavir + ritonavir , low molecular weight heparin , zinc sulfate HIV protease inhibitor Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Laboratoire De Recherche Sur Le Diabete, Université de Tlemcen ATRSS, DGRST Algeria 2020-04-01 2020-06-30 COVIDIAB-13, COVIDIAB-13, NCT04412746 Phase Not Applicable Recruiting 1 3 Months 100 ALI LOUNICI, ALI LOUNICI, Professor, Benattou ZIANE, Professor, Samia BENCHOUK, Professor 2020-06-04
ISACS-STEMI COVID-19: Primary Angioplasty for STEMI During COVID-19 Pandemic (ISACS-STEMI COVID-19) Registry Acute coronary syndrome, Coronavirus disease 19 infection, Myocardial infarction Percutaneous coronary revascularization alone Universita' Degli Studi Del Piemonte Orientale "Amedeo Avogadro" Italy 2020-05-05 2020-06-02 115/20, ISACS-STEMI COVID-19, NCT04412655 Phase Not Applicable Recruiting 1 4000 Giuseppe De Luca, Giuseppe De Luca, MD, Monica Verdoia, MD 2020-06-04
A clinical trial of nafamostat for the treatment of patients with COVID-19 infection Coronavirus disease 19 infection nafamostat (Middle East respiratory syndrome/COVID-19), University of Tokyo alone Serine protease inhibitor Sun Pharmaceutical Industries Ltd India Phase Not Applicable Not yet recruiting 1 2020-06-03
A Longitudinal Study of COVID-19 Sequelae and Immunity Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Allergy and Infectious Diseases National Institutes of Health Clinical Center US 2020-06-05 2027-12-31 20-I-0123, 200123, NCT04411147 Phase Not Applicable Recruiting 1 90 Months 900 Bryan P Higgins, R.N., Michael C Sneller, M.D. 2020-06-03
Epigenetic Tools as Prognostic Predictors in Covid19 Confusion, Coronavirus disease 19 infection, Hypotension, Respiratory distress syndrome, Tachycardia, Tachypnea, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Bakirkoy Dr. Sadi Konuk Research and Training Hospital Istanbul University Turkey 2020-05-21 2020-12-31 2020/143, NCT04411563 Phase Not Applicable Recruiting 2 7 Months 105 Asuman Gedikbasi, Assoc.Prof., Gokhan T Adas, Prof., Gokhan T. Adas, Prof, Gokhan T. Adas, Prof., Kadriye Yaşar, Prof., Nilgün Isiksacan, Assoc.Prof., Oya G. Hergünsel, MD, Intensivist, Sacide Pehlivan, Prof., Zafer Çukurova, Assoc.Prof. 2020-06-05
Menstrual Cycle Characteristics of Healthcare Professionals Coronavirus disease 19 infection, Dysmenorrhea, Menstruation disorder Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Haydarpasa Numune State Hospital Saglik bilimleri universtesi Turkey 2020-04-10 2020-11-10 HNEAH KAEK 2020/KK/, MINISTRY OF HEALTH, NCT04413058 Phase Not Applicable Recruiting 1 7 Months 200 Sevcan Arzu Arinkan, Sevcan Arzu Arinkan, M.D. 2020-06-04
OPTIMAL: Optimizing Outcomes With Physical Therapy Treatment for IndividuALs Surviving an ICU Admission for Covid-19 Anxiety disorder, Cognitive disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder ICU Recovery + Physical Therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Kentucky US 2020-05-01 2021-05-01 59097, NCT04412330, OPTIMAL Phase Not Applicable Recruiting 1 12 Months 40 Evan Cassity, MS, Kirby Mayer, DPT, PhD(c), Kirby P Mayer, PhD 2020-06-05
COVID-19 Convalescent Plasma (CCP) Transfusion Coronavirus disease 19 infection, Hypoxia, Multiple organ failure, Respiratory failure, Sepsis COVID convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Mississippi US 2020-06-01 2022-05-31 2020-0137, NCT04412486 Phase 0 Clinical Recruiting 1 24 Months 100 Gailen D Marshall, Jr., MD, PhD, Lucar Lloveras, MD, Utsav Nandi, MD, Vishnu Garla, MD 2020-06-04
COLC: COVID-19, Obesity and Lifestyle in Children Coronavirus disease 19 infection, Obesity Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Maastricht University Medical Center Netherlands 2020-05-06 2021-05-06 2020-1330, COLC, NCT04411511 Phase Not Applicable Recruiting 1 12 Months 4000 Anita CE Vreugdenhil, Anita CE Vreugdenhil, Dr., Anita CE Vreugdenhil, dr., Gabrielle L ten Velde, Drs., Judith W Lubrecht, Drs., Lisanne Arayess, Drs., Lisanne Arayess, drs. 2020-06-04
PredictCovid19: Prediction of Unfavourable Outcome in Newly Covid-19 Hospitalized Patient Coronavirus disease 19 infection RT-polymerase chain reaction alone, nasopharyngeal swab sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospices Civils De Lyon France 2019-11-11 2020-05-15 20_185, NCT04412031, PredictCovid19 Phase Not Applicable Completed 1 6 Months 802 2020-06-04
An observational clinical study of Covid-19 Analysis Exploratory Markers by RT-PCR in Blood and Urine as possible prognostic factor markers for patients with SARS-CoV-2 Coronavirus disease 19 infection RT-PCR analysis alone Hospital Universitari Quirón Dexeus Phase Not Applicable Status not specified 0 2020-06-03
A clinical trial to know the effect of Virulina along with standard treatment in covid 19 positive patients Coronavirus disease 19 infection Virulina alone, standard treatment protocol alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Natural Solutions India 2020-06-15 CTRI/2020/06/025556, PHAR/CT/VIRULINA/COVID/10052020 Phase 2 Clinical Not yet recruiting 1 30 Baburao Vikram, Dr A Gopal Rao, Dr Anil Sharma 2020-06-05
Evaluation of the efficacy and safety of a new BIOMODULIN T dosage regimen for the prevention of infections, including COVID-19, in older adults in Cuba. Confirmatory study (COVID-19) Coronavirus disease 19 infection BIOMODULIN T alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Biopreparations Center Ministerio de Salud Publica Cuba 2020-04-13 B-08-038-J05, GEC2020BMT025, RPCEC00000319 Phase 2 Clinical No longer recruiting 1 160 Comfort Macías Abraham, Luis Heredia Guerra, Mary Carmen 2020-06-04
CARED: Cholecalciferol to Improve the Outcomes of COVID-19 Patients Coronavirus disease 19 infection, Respiratory disease vitamin D alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ag Nac Promoción de la Investigación, el Desarrollo Tecnológico y la Innovación Argentina 2020-06-15 2020-12-28 001, CARED, NCT04411446 Phase 4 Clinical Not yet recruiting 1 6 Months 1265 Carlos Tajer, MD, Felipe Inserra, MD, Javier Mariani, MD, Laura Antonietti, MD, Laura Antonietti, MD MSc, León Ferder, MD, Sebastián Maristany, MD, Walter Manucha, PhD 2020-06-05
Use of Heberon Alfa R in patients confirmed for infection with SARS-CoV-2 in Cuba: Observational clinical study (COVID-19) Coronavirus disease 19 infection interferon alfa-2b follow-on biologic (intravenous), CIGB/Heber Biotec alone Interferon alpha 2 ligand Ministerio de Salud Publica Cuba 2020-03-11 2020-08-14 RPCEC00000318 Phase 4 Clinical Recruiting 7 5 Months 2005 Dr. Hubert Blas Rivero Martinez, Dr. Juan Carlos Rivero Lopez, Dr. Rafael Venegas Rodriguez, Dr. Rodolfo Emilio Dominguez Rosabal, Dr.C Julio R. Betancourt Cervantes, Dr.C. Albadio Perez Aseff, Dr.Daniel Gonzalez Rico, Dra. Lissette del Rosario Lopez Gonzalez, Dra.C Natacha Mezquia de Pedro, Ricardo Pereda Gonzalez 2020-06-04
MIIC-MI: Multi-modality Imaging and Immunophenotyping of COVID-19 Related Myocardial Injury Coronavirus disease 19 infection, Heart injury 18F-FDG alone, 68Ga-dotatate alone, CT coronary angiography alone, cardiac MRI alone, cardiac PET/MRI alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Cambridge British Heart Foundation, Cambridge University Hospitals NHS Foundation Trust, Wellcome Trust UK 2020-06-30 2021-06-30 A09565, MIIC-MI, NCT04412369 Phase Not Applicable Not yet recruiting 1 12 Months 20 Andrej Ćorović, MA MB BChir, Andrew Sage, PhD, Deepa Gopalan, MD FRCR, James HF Rudd, MD PhD FRCP FESC, Jason M Tarkin, MBBS PhD, Jason M Tarkin, MBBS, PhD, Meritxell Nus, PhD, Tian Zhao, MA MBBS PhD, Ziad Mallet, MD PhD FMedSci 2020-06-04
Study to Evaluate the Safety and Efficacy of ATYR-1923 In Patients With Severe Pneumonia Related to COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia ATYR-1923 alone Neuropilin 2 inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) aTyr Pharma Inc US 2020-06-01 2020-10-31 ATYR1923-C-003, NCT04412668 Phase 2 Clinical Recruiting 2 5 Months 30 Gennyne Walker, Shambhu Aryal, MD, aTyr Pharma Clinical Research 2020-06-05
Current and Past SARS-CoV-2 Infection and COVID-19 in Healthcare Coronavirus disease 19 infection RT PCR test alone, blood sampling alone, throat swab sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Karolinska University Hospital Sweden 2020-04-23 2020-12-31 COVID-19 STUDIEN, NCT04411576 Phase Not Applicable Recruiting 1 8 Months 40000 Joakim Dillner, Joakim Dillner, MD, PhD 2020-06-05
Echocardiography in Patients With Covid-19 Coronavirus disease 19 infection echocardiography alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Tubingen Germany 2020-03-20 2021-12-31 COVIDECHO, NCT04412460 Phase Not Applicable Recruiting 1 21 Months 500 Harry Magunia, MD, Michael Koeppen, MD 2020-06-05
ARCHITECTS: A RCT - Safety and Efficacy of Tocilizumab - Tx of Severe COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia tocilizumab (intravenous), Roche/Chugai alone IL-6 receptor antagonist, IL-6 receptor modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Queens Medical Centre US 2020-06-01 2021-12-31 ARCHITECTS, NCT04412772, RA-2020-019 Phase 3 Clinical Recruiting 1 19 Months 300 May Vawer, RN, Todd Seto, MD 2020-06-04
Effect of Laris-Teucrium Polium L.and Laris-Hyssop combined herbal medicine on the prevention of covid-19 disease Coronavirus disease 19 infection Laris-Tokrium Hisspus alone, Laris-Tokrium polium alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tabriz University of Medical Sciences Iran 2020-05-09 IR.TBZMED.REC.1399.026, IRCT20200503047280N1 Phase 3 Clinical Recruiting 1 300 Mohammad samiei, Seyyed Mohammad Bagher Fazljou, Seyyed mohammad bagher fazljou 2020-06-04
Patient Characteristics, Outcome and Thromboembolic Events Among Adult Critically Ill COVID-19 Patients With Different Anticoagulant Regimes Bleeding, Coronavirus disease 19 infection, Thromboembolism tinzaparin sodium alone Antithrombin III, Factor Xa antagonist, Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Karolinska Institutet Sweden 2020-03-06 2020-05-28 NCT04412304, THROMBOEMBOLIC EVENTS IN COVID Phase Not Applicable Completed 1 2 Months 166 Maria Cronhjort, PhD 2020-06-05
CRASH: COVID-19, Respiratory Distress and Antithrombotic Drugs in Subject's Habits Coronavirus disease 19 infection, Respiratory distress syndrome antithrombolytic therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopitaux Universitaires de Strasbourg France 2020-04-30 2020-06-30 7837, CRASH, NCT04412473 Phase Not Applicable Recruiting 1 2 Months 1000 Bernard GOICHOT, MD, Jean-Edouard TERRADE, MD, Laurine LE GOFF, MD, Saïd CHAYER, PhD, HDR, Stanislas DEMUTH, MD, Vincent CASTELAIN, MD, PhD 2020-06-05
CCC: Cardiac Coronavirus Health Care Workers Coronavirus disease 19 infection, Heart injury, Heart valve disease, Ischemic heart disease, Myocarditis, Pericarditis blood sampling alone, cardiac magnetic resonance alone, electrocardiogram alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) AORTICA Group Instituto de Investigación Biomédica de Salamanca, University Hospital of Salamanca Spain 2020-05-25 2020-07-11 CCC, CCC_2020, NCT04413071 Phase Not Applicable Not yet recruiting 1 1 Month 100 Pedro L Sanchez, Pedro L Sanchez, MD, PhD, Rocio Eiros, MD 2020-06-04
Study of Standard of Care Plus Intravenous Immunoglobulin (IVIG) Compared to Standard of Care Alone in the Treatment of COVID-19 Infection Coronavirus disease 19 infection, Respiratory failure standard of Care alone, Octagam plus methylprednisolone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sharp HealthCare Octapharma AG US 2020-04-28 2020-11-30 2004902, COVID-IVIG, NCT04411667 Phase 4 Clinical Recruiting 2 7 Months 40 Adriana Valdez-Hernandez, RN, Cary Murphy, RN, George Sakoulas, MD, Katie Miller, Matthew Geriak, PharmD 2020-06-05
Effect of Using Barrier Devices for Intubation in COVID-19 Patients Coronavirus disease 19 infection aerosol box alone, transparent sheet alone Healthy volunteers accepted Kocaeli Derince Training and Research Hospital Turkey 2020-06-10 2020-06-30 2020/56, NCT04412226 Phase Not Applicable Not yet recruiting 1 13 ASIM E OZBEK, MD, ASIM ENESOZBEK 2020-06-04
Safety and Efficacy of Tofacitinib in Hospitalized Participants With COVID-19 Pneumonia Who Are Receiving Standard of Care Therapy Coronavirus disease 19 infection, Viral pneumonia standard of care alone, tofacitinib citrate (oral, inflammation), Pfizer alone JAK tyrosine kinase inhibitor, Jak1 tyrosine kinase inhibitor, Jak3 tyrosine kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Pfizer Inc 2020-05-30 2020-10-18 A3921377, NCT04412252 Phase 2 Clinical Not yet recruiting 0 4 Months 265 Pfizer CT.gov Call Center 2020-06-04
Risk Factors for Prolonged Invasive Mechanical Ventilation in COVID-19 Acute Respiratory Distress Syndrome Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure, Viral pneumonia Invasive mechanical ventilation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Azienda USL di Bologna Ospedale Maggiore di Bologna Italy 2020-02-01 2020-10-30 273/2020/OSS/AUSLBO, NCT04411459 Phase Not Applicable Recruiting 18 8 Months 600 Alessandro Gatta, MD, Andrea Marudi, MD, Antonella Potalivo, MD, Chiara Capozzi, Cristiana Laici, Cristiana Simonetti, MD, Davide Colombo, MD, Emanuele Russo, MD, Federica Damiani, MD, Iacopo Cappellini, MD, Lorenzo Gamberini, Lorenzo Gamberini, MD, Maria Concetta Lanza, MD, Maurizio Fusari, MD, Mirco Leo, MD, Raffaella Papa, MD, Savino Spadaro, MD, Silvia Magnani, MD, Silvia Pareschi, MD, Tommaso Tonetti 2020-06-04
Feasibility Study of Anti-SARS-CoV-2 Plasma Transfusions in COVID-19 Patients With SRD Coronavirus disease 19 infection, Multiple organ failure, Respiratory distress syndrome, Respiratory failure, Septic shock SARS-CoV-2 convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ascension South East Michigan US 2020-04-07 2020-12-31 1589349, NCT04411602 Phase 1 Clinical Recruiting 3 8 Months 90 Debra J Levan, DO, Shukri David, MD, Teresa Jacobson, BS, Yulia Abidov, RN 2020-06-05
Using interferon to treat COVID-19 Coronavirus disease 19 infection interferon alpha 2a alone, interferon beta 1a alone, standard care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mashhad University of Medical Sciences Iran 2020-05-23 IR.MUMS.REC.1399.219, IRCT20161206031256N3 Phase 2/Phase 3 Clinical Recruiting 1 76 Haniye Ghaffari-nazari, Maryam Khoshkui, Maryam khoshkhui, Maryam khoshkui, maryam Khoshkhui 2020-06-04
Safety and Immunogenicity Study of an Inactivated SARS-CoV-2 Vaccine for Preventing Against COVID-19 Coronavirus disease 19 infection SARS-CoV-2 vaccine (inactivated/Vero cells/intramuscular, COVID-19), Institute of Medical Biology Chinese Academy of Medical Sciences alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Chinese Academy of Medical Sciences West China Second University Hospital, Yunnan Center for Disease Control and Prevention China 2020-05-15 2021-09-30 20200401, NCT04412538 Phase 1/Phase 2 Clinical Recruiting 1 16 Months 942 Qihan Li, Qihan Li, PhD, Qin Yu, Xiaoqiang Liu, Yanchun Che, Researcher 2020-06-05
Effectiveness of the combined treatment with hydroxycloroquine and azithromycin versus lopinavir/ritonavir + hydroxycloroquine in hospitalized patients with confirmed COVID-19 infection Coronavirus disease 19 infection azithromycin plus hydroxycloroquine Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Basque Health Service Spain 2020-05-29 2020-001605-23, HUA-COVID-19 Phase 4 Clinical Recruiting 1 108 Inés Pérez Francisco 2020-06-05
A Study in Patients With COVID-19 and Respiratory Distress Not Requiring Mechanical Ventilation, to Compare Standard-of-care With Anakinra and Tocilizumab Treatment The Immunomodulation-CoV Assessment (ImmCoVA) Study Coronavirus disease 19 infection, Respiratory distress syndrome anakinra alone, standard-of-care treatment alone, tocilizumab alone, Variable regimens including dalteparin sodium , paracetamol , tinzaparin sodium Antithrombin III, Factor IIa antagonist, Factor Xa antagonist, Low molecular weight heparin, Type I IL-1 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Karolinska Institutet Karolinska University Hospital Sweden 2020-06-30 2021-02-28 2020-001748-24, NCT04412291 Phase 2 Clinical Not yet recruiting 1 8 Months 120 Jon Lampa, Jon Lampa, MD PhD, Jonas Sundén-Cullberg, MD PhD 2020-06-05
iLeukPulm: Study of Sargramostim in Patients With COVID-19 Coronavirus disease 19 infection, Hypoxia sargramostim alone, standard of care alone CSF-1 agonist, GM-CSF receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Partner Therapeutics Inc 2020-06-30 2021-01-31 NCT04411680, PTX-001-002, iLeukPulm Phase 2 Clinical Not yet recruiting 0 7 Months 60 Fiona Garner, PhD 2020-06-05
VIGIL: Use of PCR-Sars-CoV-2 in Children Coronavirus disease 19 infection PCR alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) Centre Hospitalier Intercommunal Creteil ACTIV, France, Association Française de Pédiatrie Ambulatoire- AFPA, GFRUP, GPIP (FR) France 2020-06-01 2021-05-31 NCT04412317, VIGIL, VIGIL Phase Not Applicable Not yet recruiting 2 12 Months 600 Corinne LEVY, MD, Corinne Levy, MD 2020-06-04
Clinical Trial to Evaluate CERC-002 in Adults With COVID-19 Pneumonia and Acute Lung Injury Acute lung injury, Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia CERC-002 alone, standard of care alone Tumor necrosis factor 14 ligand inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Aevi Genomic Medicine Inc, Cerecor Inc 2020-06-30 2020-11-30 CERC-002-CVID-201, NCT04412057 Phase 2 Clinical Not yet recruiting 0 5 Months 82 H. Jeffrey Wilkins, H. Jeffrey Wilkins, MD 2020-06-04
FRA-COVID: Frailty in Elderly Patients With COVID-19 Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Milano-Bicocca Italy 2020-03-01 2021-03-01 FRA-COVID, FRA-COVID, NCT04412265 Phase Not Applicable Recruiting 1 12 Months 300 Giuseppe Bellelli 2020-06-05
Lung Ultrasound for Assessment of Patients With Moderate to Severe Covid-19 Coronavirus disease 19 infection, Respiratory distress syndrome lung ultrasound alone, routine care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dalarna County Council Sweden 2020-05-20 2020-12-31 LUS-COVID001, NCT04412551 Phase Not Applicable Recruiting 1 7 Months 50 Maria Hardstedt, Maria Hardstedt, MD/PhD, Maria Hårdstedt, PhD 2020-06-04
Cyclosporine in Patients With Moderate COVID-19 Coronavirus disease 19 infection ciclosporin, Novartis alone Calcineurin inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Pennsylvania US 2020-06-30 2020-12-31 842998, NCT04412785 Phase 1 Clinical Not yet recruiting 1 6 Months 20 Emily Blumberg, MD, Joan Gilmore, Karen Dengel, RN 2020-06-04
NETSINCOVID: Covid-19: Possible Role of Neutrophil Extracellular Traps Coronavirus disease 19 infection electron microscopy alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Azienda Ospedaliera Universitaria Integrata Di Verona Italy 2020-06-01 2021-12-31 NCT04412382, NETS IN COVID-19, NETSINCOVID Phase Not Applicable Not yet recruiting 1 19 Months 100 CHIARA MOZZINI, MD-PhD, Chiara Mozzini, DOMENICO GIRELLI, MD-PhD 2020-06-04
PROTECT-ASUC: Covid-19 Pandemic Response Of Assessment, Endoscopy and Treatment in Acute Severe Ulcerative Colitis Coronavirus disease 19 infection, Ulcerative colitis Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hull University Teaching Hospitals NHS Trust UK 2020-05-20 2020-07-31 284030, NCT04411784, PROTECT-ASUC Phase Not Applicable No longer recruiting 1 2 Months 200 Shaji Sebastian 2020-06-04
A trial to evaluate Digid Cantisense SARS-CoV-2 Test to detect SARS-CoV-2 viruses Coronavirus disease 19 infection Digid Cantisense SARS-CoV-2 Test alone Helmholtz Zentrum fur Infektionsforschung GmbH US Phase Not Applicable Planned 1 2020-06-03
REsCue: A Randomized, Double-Blind, Placebo-Controlled, Phase II Study to Evaluate the Safety and Efficacy of Rayaldee (calcifediol) Extended-release Capsules to Treat Symptomatic Patients Infected with SARS-CoV-2 Coronavirus disease 19 infection calcifediol (oral, vitamin D insufficiency), OPKO alone OPKO Health Inc US REsCue Phase 2 Clinical Not yet recruiting 1 166 2020-06-03
Effect of Ayurvedic medicine in the Prophylaxis for COVID-19 of Police personnel Dept of AYUSH, TS and CCRAS- NIIMH, Hyderabad Coronavirus disease 19 infection Raksha Kit alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) DR BRKR GOVT AYURVEDIC MEDICAL COLLEGE India 2020-06-15 CTRI/2020/05/025493 Phase 2/Phase 3 Clinical Not yet recruiting 1 1500 Dr Madikonda Praveen kumar 2020-06-04
Mental impact of SARS Covid-19 disease outbreaks among suspects coming to AIIMS Rishikesh, their close contacts, and associated healthcare providers Anxiety disorder, Coronavirus disease 19 infection, Depression Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences India 2020-06-10 CTRI/2020/05/025494 Phase Not Applicable Not yet recruiting 1 3000 Prasan Kumar Panda 2020-06-04
A study to estimate drug levels in health care workers on COVID infection prophylaxis Coronavirus disease 19 infection hydroxychloroquine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Norwich Clinical Services Pvt Ltd. St. John's Research Institute India 2020-05-29 COVID-19-2020-01, CTRI/2020/05/025466 Phase Not Applicable Not yet recruiting 1 24 Dr Denis Xavier MD MSc, Dr Rajeev M Patil 2020-06-05
CUR-TREATCoV2: Effect of nutritional supplement made from Haldi and Black Pepper to prevent and treat active corona virus infection Coronavirus disease 19 infection curcumin with black pepper alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Siddhivinayak Pain Relief Center GMC Baramati and rural hospital, Seth GS Medical College India 2020-05-29 CTRI/2020/05/025482, CUR-TREATCoV2 Phase Not Applicable Not yet recruiting 1 50 DrKirti S Pawar 2020-06-05
Psychological and Physical Aspect of Covid-19 Patient Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Angkatan Tentera Tuanku Mizan Malaysia 2020-05-30 55028, NMRR-20-1075-55028 Phase Not Applicable Recruiting 1 278 Dr SITI NORDIANA DOLLAH 2020-06-04
Screening of healthcare workers, Doctors and Nurses working in Covid-19 wards using a continous wearable watch device Coronavirus disease 19 infection Empatica E 4 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Tata Consultancy Services Ltd India 2020-06-10 CTRI/2020/05/025495 Phase Not Applicable Not yet recruiting 1 30 Kayapanda Mandanna 2020-06-04
KAP on COVID-19 among Social Media Users in Malaysia during CMCO Coronavirus disease 19 infection Hospital Rehabilitasi Cheras Malaysia 2020-06-01 55142, NMRR-20-1064-55142 Phase Not Applicable Status not specified 1 Dr Darmini a/p Selvan 2020-06-04
Use of Clevira in COVID19 patients Coronavirus disease 19 infection Clevira alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Apex Laboratories Pvt Ltd India 2020-06-02 CTRI/2020/05/025483 Phase 3 Clinical Not yet recruiting 1 100 Dr R Narayana Babu, Dr Ramesh Kannan 2020-06-05
NDEA COVID-19: NDEA COVID-19 Coronavirus disease 19 infection Ministry of Health, Malaysia China 2020-06-01 55031, NDEA COVID-19, NMRR-20-1060-55031 Phase Not Applicable Status not specified 1 Ms Nurhafiza binti Md Hamzah 2020-06-04
CPC: Study on the effect of Chyavanprash Lehyam as a prophylactic measure among high risk population (Health Care Workers/Containment Zone Population) exposed to COVID-19 Coronavirus disease 19 infection Chyavanprash Lehyam alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Central Council for Research in Ayurveda and Siddha India 2020-06-03 CPC, CTRI/2020/05/025484 Phase 2/Phase 3 Clinical Not yet recruiting 1 5000 Dr P V V Prasad 2020-06-05
Psychological Impact Among Patients with COVID-19, Perak Coronavirus disease 19 infection, Psychiatric disorder Hospital Raja Permaisuri Bainun Malaysia 2020-05-29 54983, NMRR-20-1053-54983 Phase Not Applicable Status not specified 1 Doctor Loo Tsui Huei 2020-06-04
Effect of Prednisolone on treatment of COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome prednisolone alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tehran University of Medical Sciences Iran 2020-03-29 IR.TUMS.VCR.REC.1399.055, IRCT20081027001411N3 Phase 2 Clinical Recruiting 3 60 Ahmadreza Jamshidi, Mahdi Mahmoudi, Mahdi Vojdanian, Maryam Edalatifard, Mohammad Abdolahi, Mohammad Ali Sahraian, Sasan Falahi 2020-06-04
A clinical trial of GC-5131A for the potential treatment COVID-19 Coronavirus disease 19 infection GC-5131A alone Immunoglobulin agonist GC Pharma 2020-07-31 Phase Not Applicable Planned 0 2020-06-05
A clinical study to assess the effect of rNAPc2 in the potential treatment of COVID-19 associated coagulopathy (CAC) and the related inflammatory response Blood clotting disorder, Coronavirus disease 19 infection AB-201, Arca Biopharma alone Factor VII antagonist, Tissue factor inhibitor ARCA Biopharma Inc 2020-12-31 Phase Not Applicable Planned 0 2020-06-03
Humoral Immunity Against SARS-CoV-2 in Liver Transplanted Patients After COVID-19 in Comparison With Immunocompetent Patients Coronavirus disease 19 infection ploymerase chain reaction alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital General Universitario Gregorio Marañon Spain 2020-05-29 2021-06-30 NCT04410471, SERO-COVID19-TH Phase Not Applicable Recruiting 3 13 Months 300 Magdalena Salcedo, Magdalena Salcedo, MD PhD, Maricela Valerio, MD, Victor Fernandez Alonso, Victor Fernández, Nurse 2020-06-04
The effect of surfactant on clinical outcome of patients with COVID-19 Coronavirus disease 19 infection Beraksurf alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shahid Beheshti University of Medical Sciences Iran 2020-04-20 IR.SBMU.RETECH.REC.1399.016, IRCT20091201002804N12 Phase 3 Clinical Recruiting 1 60 Afshin Zarghi, Ali Dabbagh 2020-06-04
Study of Merimepodib in Combination With Remdesivir in Adult Patients With Advanced COVID-19 Coronavirus disease 19 infection, Lower respiratory tract infection merimepodib plus remdesivir COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, Inosine monophosphate dehydrogenase inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Biosig Technologies Inc US 2020-06-30 2020-08-31 NCT04410354, VC-02-01 Phase 2 Clinical Not yet recruiting 3 2 Months 40 Andrew Badley, MD, Andrew D. Badley, Claudia Libertin, MD, Robert Orenstein, DO, Study Coordinator, Zelalem Temesgen, MD 2020-06-04
OBELIX: COVID-19 Blood Pressure Endothelium Interaction Study Coronavirus disease 19 infection ambulatory blood pressure monitoring alone, electrocardiogram monitoring alone, nailbed capillaroscopy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) NHS Greater Glasgow and Clyde University of Glasgow UK 2020-06-01 2021-05-31 GN20CA245, NCT04409847, OBELIX Phase Not Applicable Not yet recruiting 1 12 Months 70 Katriona Brooksbank, Rhian M Touyz 2020-06-04
A clinical trial of AAVCOVID for the prevention of COVID-19 infection Coronavirus disease 19 infection AAVCOVID alone COVID19 Spike glycoprotein modulator Massachusetts Eye Research and Surgery Institution, Massachusetts General Hospital AveXis Inc 2020-12-31 Phase Not Applicable Planned 0 2020-06-02
Immune Response and Risk of Serious Infection to SARS-Cov2 Coronavirus disease 19 infection flow cytometry alone, routine care blood test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire Dijon France 2020-06-30 2021-05-31 GHESQUIERE AOIC 2020, NCT04410432 Phase Not Applicable Recruiting 1 11 Months 63 Thibault GHESQUIERE 2020-06-05
MICRO-COV: Microbiota in COVID-19 Patients for Future Therapeutic and Preventive Approaches Bacterial infection, Coronavirus disease 19 infection, Lung injury, Pseudomonas aeruginosa infection, Respiratory distress syndrome, Staphylococcus aureus infection, Streptococcus pneumoniae infection, Viral pneumonia biological sampling alone, sublingual microscopy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Zurich Switzerland 2020-04-09 2023-12-31 2020-00646, MICRO-COV, NCT04410263 Phase Not Applicable Recruiting 1 44 Months 300 Philipp Buehler, MD, Philipp K Buehler, PB, Silvio Brugger, SB 2020-06-04
PREPARE IBD: Physician Responses to Disease Flares and Patient Adaptation in Relation to Events in Inflammatory Bowel Disease During COVID-19 Pandemic Coronavirus disease 19 infection, Inflammatory bowel disease Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hull University Teaching Hospitals NHS Trust UK 2020-05-22 2020-08-31 284920, NCT04410484, PREPARE IBD Phase Not Applicable No longer recruiting 1 3 Months 1500 Shaji Sebastian 2020-06-05
P2Et Extract in the Symptomatic Treatment of Subjects With COVID-19 Adult respiratory distress syndrome, Coronavirus disease 19 infection, Hypotension, Hypoxia, Sepsis, Septic shock, Viral pneumonia Variable regimens including P2Et extract , hydroxychloroquine , lopinavir + ritonavir HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Universitario San Ignacio Javeriana University Colombia 2020-06-30 2021-06-30 CS002-COVID19, NCT04410510 Phase 2/Phase 3 Clinical Not yet recruiting 1 12 Months 100 Angel Garcia, MD. MSc. PhD(c), Margarita Manrrique, MD, MSc 2020-06-03
Psychological Impact of the Corona Virus Pandemic in Individuals With Psychiatric Disorders Anxiety disorder, Coronavirus disease 19 infection, Depression, Psychiatric disorder Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Medical University of Graz Austria 2020-04-28 2021-04-28 32-363 EX 19/20, NCT04410835 Phase Not Applicable Recruiting 1 12 Months 1000 Eva Reininghaus, Asszo.Prof., Eva Reininghaus, Prof., Nina Dalkner, PD Dr. 2020-06-02
Evaluation of Therapeutic Effects of Melatonin by Inhibition of NLRP3 Inflammasome in COVID-19 Patients Coronavirus disease 19 infection melatonin alone, usual treatment alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Baqiyatallah University of Medical Sciences Iran 2020-05-12 2020-09-25 IR.BMSU.REC.1399.039, NCT04409522 Phase 2 Clinical Recruiting 1 4 Months 55 Mohammad Sadegh Bagheri Baghdasht 2020-06-03
COVID 19 Viral Clearance Among the Infected Healthcare Workers In Assiut University Hospitals Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Assiut University Egypt 2020-06-30 2021-06-30 COVID19 AMONG HCWS, NCT04409574 Phase Not Applicable Not yet recruiting 1 12 Months 31 Azza Ezzeldin, professor, Mariam Roshdy Elkhayat, Mariam elkhayat, lecturer 2020-06-05
Pharmacy Education During Covid-19 Outbreak Coronavirus disease 19 infection Adolescents (13-17 yrs), Young Adults (18-44 yrs) Damanhour University Egypt 2020-06-30 2021-09-30 EDUCATIONAL PROCESS & COVID-19, NCT04409951 Phase Not Applicable Not yet recruiting 1 15 Months 100 Noha El Bassiouny, PhD 2020-06-02
Prognosis in Pregnant With COVID-19 Coronavirus disease 19 infection Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Istanbul Bakirkoy Maternity and Children Diseases Hospital Turkey 2020-03-15 2020-05-28 MTALMACPROGNOSIS, NCT04409249 Phase Not Applicable Completed 1 2 Months 150 Merve Aldikactioglu Talmac, MD 2020-06-02
Treatment With CSL-312 in Adults With Coronavirus Disease 2019 (COVID‑19) Coronavirus disease 19 infection, Viral pneumonia garadacimab alone, standard of care alone Factor XIIa antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) CSL Ltd 2020-06-30 2020-12-31 CSL312_COVID-19, NCT04409509 Phase 2 Clinical Not yet recruiting 0 6 Months 124 Study Director, Trial Registration Coordinator 2020-06-04
Phase III Study to Determine if RTB-101 Reduces the Severity of COVID-19 in Older Adults Residing in Nursing Homes Coronavirus disease 19 infection dactolisib alone Phosphoinositide 3-kinase inhibitor, mTOR complex 1 inhibitor, mTOR complex 2 inhibitor Aged Adults (65-79 yrs), Elderly Adults (80 and over) resTORbio Inc Brown University School of Public Health, Genesis HealthCare System, Insight Therapeutics, LLC US 2020-05-31 2020-10-31 NCT04409327, RTB101-210 Phase 3 Clinical Recruiting 1 5 Months 550 Medical Director, Medical Monitor 2020-06-05
Whole Blood Collection From Individuals in the Convalescent Phase of SARS-CoV-2 Infection Coronavirus disease 19 infection whole blood sampling alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Medical College of Wisconsin Versiti US 2020-05-31 2021-05-31 NCT04409184, PRO00037957 Phase Not Applicable Not yet recruiting 1 12 Months 50 Weiguo Cui 2020-06-04
GLYCOVID-19: Glycemia and Cardiac Function in Patients With COVID-19 Coronavirus disease 19 infection, Insulin dependent diabetes, Non-insulin dependent diabetes echocardiography alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Steno Diabetes Center Odense Denmark 2020-04-20 2020-11-30 GLYCOVID-19, H-20024279, NCT04410718 Phase Not Applicable Recruiting 2 7 Months 100 Andreas Andersen, Andreas Andersen, MD 2020-06-04
MOHC: Home Detox in Medication Overuse Headache (MOH) During Covid-19 Emergency Coronavirus disease 19 infection, Headache bridge therapy alone, mindfulness program alone, Variable regimens including bromazepam , indomethacin , metoclopramide , pantoprazole , prednisone Benzodiazepine receptor agonist, H+ K+ ATPase inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fondazione IRCCS Istituto Neurologico Carlo Besta Italy 2020-06-30 2022-07-31 MOH, MOHC, NCT04410536 Phase 2 Clinical Not yet recruiting 1 25 Months 25 Licia Grazzi, MD, Renato Mantegazza, MD 2020-06-04
Povidone-Iodine Versus Essential Oil Versus Tap Water Gargling For COVID-19 Patients (GARGLES) Coronavirus disease 19 infection Listerine alone, hydrogen peroxide alone, povidone-iodine (Betadine) alone, real-time reverse transcriptase-polymerase chain reaction test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universiti Sains Islam Malaysia Universiti Kebangsaan Malaysia Medical Centre Malaysia 2020-06-15 2020-08-15 NCT04410159, USIMALAYSIA Phase 2 Clinical Not yet recruiting 1 2 Months 20 NAJMA KORI, NURUL A MOHAMED, PETRICK PERIYASAMY, WAN SHAHIDA WAN SULAIMAN 2020-06-04
Lung Function, Exercise Capacity and Health-Related Quality of Life After Severe COVID-19 Coronavirus disease 19 infection, Lower respiratory tract infection, Respiratory distress syndrome, Viral pneumonia Cardiopulmonary exercise test alone, Spirometry alone, lung function test alone Federal University of Rio Grande do Sul Conselho Nacional de Desenvolvimento Cientifico e Tecnologico - CNPq, Federal University of Health Science of Porto Alegre, Hospital Nossa Senhora da Conceicao, Hospital de Clinicas de Porto Alegre, Instituto de Educação e Pesquisa do Hospital Moinhos de Vento, Universidado de Passo Fundo Brazil 2020-05-15 2022-08-02 2020-0169, NCT04410107 Phase Not Applicable Recruiting 5 26 Months 134 Danilo C Berton, Dr, Igor G Benedetto, Dr, Marcelo B Gazzana, Dr, Marcelo F Nogueira, Dr, Mauricio R Leite, Dr, Nathalia Mendes, Dr, Paulo JZ Teixeira, Dr, Renata D Marques, Dr 2020-06-03
COVID-PACT: Prevention of Arteriovenous Thrombotic Events in Critically-Ill COVID-19 Patients Trial Arterial thrombosis, Coronavirus disease 19 infection, Deep vein thrombosis Variable regimens including clopidogrel , enoxaparin sodium , heparin Low molecular weight heparin, P2Y12 purinoceptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The TIMI Study Group US 2020-06-30 2021-05-31 2020P001404, CCCTN/TIMI COVID-PACT, COVID-PACT, NCT04409834 Phase 4 Clinical Not yet recruiting 1 11 Months 750 David A Morrow, MD, MPH, Marc S Sabatine, MD, MPH, Vivian Baird-Zars 2020-06-05
Lung Fibrotic Changes Associated With SARS-CoV-2 Infection Coronavirus disease 19 infection, Pulmonary fibrosis, Viral pneumonia chest CT alone, forced spirometry alone, plethysmography alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundacion Incliva Spain 2020-05-21 2021-07-31 INC-CVD-2020-01, NCT04409275 Phase Not Applicable Recruiting 1 14 Months 500 Jaime Signes-Costa, Jaime Signes-Costa, MD, PhD 2020-06-03
A study to assess safety and efficacy of CT-P38 for the treatment of COVID-19 Coronavirus disease 19 infection CT-P38 alone Celltrion Healthcare Co Ltd Phase Not Applicable Planned 0 2020-06-05
DMB: A study to assess the usefulness of combination of Vitamin D, magnesium and Vitamin B12 in older COVID-19 patients Coronavirus disease 19 infection intensive care support alone, oxygen therapy alone, Variable regimens including magnesium , vitamin B12 , vitamin D Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Singapore Health Services Pte Ltd Singapore 2020-03-02 2020-05-15 CIRB 2020/2344, DMB, ISRCTN15324611 Phase Not Applicable Completed 1 2 Months 40 Dr L Ho 2020-06-03
A Study to assess CT-P27 for effective treatment for COVID-19 Coronavirus disease 19 infection CT-P27 alone Hemagglutinin modulator Celltrion Healthcare Co Ltd Phase 2b Clinical Planned 0 Ki-Sung Kwon 2020-06-02
Effects of the COVID-19 Health Emergency on Biopsychosocial Health Coronavirus disease 19 infection WHOQOL-BREF survey alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of New Mexico US 2020-05-07 2021-03-31 20-266, NCT04409535 Phase Not Applicable No longer recruiting 1 10 Months 500 Carla Wilhite, DOT 2020-06-03
COVID-19 PCR Test Results in Asymptomatic Pregnants Coronavirus disease 19 infection reverse transcription polymerase chain reaction alone Healthy volunteers accepted, Female Istanbul Medipol University Hospital Turkey 2020-04-10 2020-05-21 GPOLAT1, NCT04410939 Phase Not Applicable Completed 1 1 Month 179 2020-06-03
DISCONNECT-1: Dismantling Covid Induced Neutrophil Extracellular Traps Coronavirus disease 19 infection, Dyspnea, Respiratory disease dornase alfa alone Deoxyribonuclease I stimulator, Deoxyribonuclease stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Exactis Innovation Hamilton Health Sciences Corp, McGill University Health Center, Research Institute of the McGill University Health Centre, Roche Holding AG, Sir Mortimer B Davis Jewish General Hospital Canada 2020-06-30 2021-01-31 DISCONNECT-1, DISCONNECT-1, NCT04409925 Phase 1 Clinical Not yet recruiting 1 7 Months 25 Diana Salazar, MSc, MBA, Jonathan Spicer, MD, Rosa Christodoulopoulos, PhD 2020-06-05
CO-RNPC: Evaluation of Changes in Weight, Sleep, and Other Psycho-behavioral Parameters During Covid-19 Confinement in Subjects Monitored by the RNPC Network Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Grenoble France 2020-05-08 2020-10-08 38RC20.150, CO-RNPC, NCT04409197 Phase Not Applicable Recruiting 1 5 Months 4000 Jean-Louis PEPIN 2020-06-03
TRASCOV: Evaluation of Additional Treatments for COVID-19: a Randomized Trial in Niger Coronavirus disease 19 infection Variable regimens including lopinavir + ritonavir , paracetamol , vitamin C HIV protease inhibitor Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Epicentre (MSF) Centre for Medical Research and Health (Cermes), Niamey, Ministry of Public Health, Niger, Université Abdou Moumouni Niger 2020-06-01 2021-12-31 NCT04409483, TRASCOV, TRASCOV Phase 3 Clinical Not yet recruiting 1 19 Months 928 Eric Adehossi, Rebecca F Grais 2020-06-03
UroCovid: The Utility of Enhanced Pre and Post-surgical Work-out to Prevent the Spread of COVID-19 in a Large Urology Department Coronavirus disease 19 infection RT-PCR alone Fundacio Puigvert Spain 2020-03-20 2020-12-31 FUNDACIÓPUIGVERT, NCT04409899, UroCovid Phase Not Applicable Recruiting 1 9 Months 300 Alberto Breda, MD, Asier Mercadé Sanchez, MD, Carles Alonso Tarres, MD, PhD, Charo Montañes Bermudez, MD, Francesco Sanguedolce, MD, PhD, Joan Palou Redorta, Prof, Josep Balaña Lucena, MD, Maite Lopez Guerrero, MªJosé Martinez Barcina, MD, Patricia Fernandez de la Llama, MD, Patricia Fernandez-Llama, MD, PhD, Raquel Lopez Martinez, Rosalia Santos da Silva, MD, Sergi Sabaté Tenas, MD 2020-06-03
Pulmonary Optical Coherence Tomography in COVID-19 Patients Adult respiratory distress syndrome, Coronavirus disease 19 infection, Inflammatory disease, Lung embolism, Thrombosis, Viral pneumonia 5 Fr multipurpose catheter (Cordis) alone, 5Fr MP catheter alone, 6 Fr 11 cm sheath alone, Recover catheter (Hexacath) alone, Storq wire (Cordis) alone, angiography alone, contrast CT scan alone, femoral vein echo-guided puncture alone, iodinated contrast administration alone, pulmonary optical coherence tomography alone, selective pulmonary artery cannulation alone, trans-thoracic echocardiography alone, unfractionated heparin alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) IRCCS San Raffaele Italy 2020-05-27 2020-06-30 NCT04410549, OCT COVID Phase 2 Clinical Recruiting 1 1 Month 10 MARCO BRUNO MARIA ANCONA, SUB INVESTIGATOR, MATTEO MONTORFANO, PRINCIPAL INVESTIGATOR, Marco Bruno Maria Ancona, Sub Investigator, Matteo Montorfano, Matteo Montorfano, PI 2020-06-05
AMPoL: Antiseptic Mouthwash / Pre-Procedural Rinse on SARS-CoV-2 Load (COVID-19) Coronavirus disease 19 infection CloSYS mouthwash, Rowpar Pharmaceutical Inc alone, Crest Pro-Health Multi-Protection mouthwash alone, Oral-B Mouth Sore mouthwash alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of California San Francisco US 2020-07-01 2021-08-31 20-30874, AMPoL, NCT04409873, R00RG2901 Phase 2 Clinical Not yet recruiting 1 14 Months 120 Sepideh Banava, DDS, MPH, Stuart A Gansky, DrPH 2020-06-03
TRACK-COVID: Investigation of COVID-19 symptoms and potential immunity in the general population Coronavirus disease 19 infection Healthy volunteers accepted University of Cambridge Health Data Research UK, National Institute for Health Research (NIHR) UK 2020-03-27 2021-06-06 2, IRAS 283239, ISRCTN55886926, TRACK-COVID Phase Not Applicable Not yet recruiting 2 14 Months 90000 Dr Amy McMahon, Prof DiAngelantonio 2020-06-05
HBOT: Hyperbaric Oxygen Therapy in Non-ventilated COVID-19 Patients Coronavirus disease 19 infection, Respiratory insufficiency antibiotic therapy alone, bronchodilator therapy alone, hyperbaric oxygen chamber (RestorixHealth) alone, hyperbaric oxygen therapy alone, oxygen alone, standard treatment alone, steroid therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Maimonides Medical Center US 2020-06-01 2021-03-30 120-20-ASF, HBOT, NCT04409886 Phase 2 Clinical Not yet recruiting 1 9 Months 30 Gene Sobol, Ory Weisel, Ory Weisel, MD 2020-06-03
ATTAC-19: Aggrenox To Treat Acute Covid-19 Coronavirus disease 19 infection, Hypoxia dipyridamole + acetylsalicylic acid (stroke), Boehringer alone, standard of care alone Cyclooxygenase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rutgers University Boehringer Ingelheim International GmbH US 2020-06-21 2021-12-15 ATTAC-19, NCT04410328, PRO2020001399 Phase 3 Clinical Not yet recruiting 1 17 Months 132 Amit Singla, MD, Olga Kovalenko, D, PhD, CCRC 2020-06-03
J-COVID-R: A retrospective study on serum markers in the diagnosis and differentiation of COVID-19 Coronavirus disease 19 infection, Pneumonia real time PCR alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Japanese Red Cross Medical Center Japan 2020-02-01 J-COVID-R, UMIN000040617 Phase Not Applicable Recruiting 1 200 Takehiro Izumo 2020-06-04
J-COVID-RP: Retrospective study on clinical and pathological aspects of COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Japanese Red Cross Medical Center Japan 2020-02-01 J-COVID-RP, UMIN000040616 Phase Not Applicable Recruiting 1 5 Takehiro Izumo 2020-06-04
J-COVID-RT: A retrospective study on the therapeutic effect of tocilizumab on COVID-19 Coronavirus disease 19 infection tocilizumab alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Japanese Red Cross Medical Center Japan 2020-02-01 J-COVID-RT, UMIN000040614 Phase Not Applicable Recruiting 1 20 Takehiro Izumo 2020-06-04
Convalescent Plasma for the Treatment of Patients With Severe COVID-19 Infection Coronavirus disease 19 infection Convalescent Plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National and Kapodistrian University of Athens Hellenic Society of Haematology Greece 2020-04-23 2021-09-15 245-14-4-20, NCT04408209 Phase 2 Clinical Recruiting 6 16 Months 60 Aikaterini Niarchou, Ioanna Charitaki, Meletios Athanasios Dimopoulos 2020-06-04
H4H-01: The effect of Alfalife in reducing low-grade inflammation Coronavirus disease 19 infection, Diabetes mellitus, Inflammatory disease, Weight gain Alfalife alone, balanced hypolipidemic and isocaloric diet intake alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Digitcal Srl Freia Farmaceutici Srl Italy 2020-01-15 2020-10-31 H4H-01, H4H-01, ISRCTN12319920 Phase Not Applicable Not yet recruiting 1 9 Months 24 Dr Lina Giuseppina Gentile, Dr Maurizio Cipolla, Prof Antonio V. Gaddi, Prof Francesco Visioli 2020-06-03
COVIDHomeless: Morbi-mortality by COVID-19 Among Homeless People in Marseille: a Cohort Study Coronavirus disease 19 infection serological test alone, virological test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux De Marseille France 2020-05-28 2021-01-27 2020-32, 2020-A01398-31, COVIDHomeless, NCT04408131 Phase Not Applicable Recruiting 1 8 Months 2000 Aurelie TINLAND, PH, Jean-Olivier ARNAUD, Director 2020-06-03
COVID-19 HD: High Versus Low LMWH Dosages in Hospitalized Patients With Severe COVID-19 Pneumonia and Coagulopathy Coronavirus disease 19 infection, Thromboembolism, Viral pneumonia enoxaparin sodium biosimilar, Techdow alone Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Modena Italy 2020-06-30 2021-06-30 2020-001972-13, COVID-19 HD, NCT04408235 Phase 3 Clinical Not yet recruiting 1 12 Months 300 Marco Marietta, MD, Pasquale Mighali 2020-06-03
GLS-1200 Topical Nasal Spray to Prevent SARS-CoV-2 Infection (COVID-19) in Health Care Personnel Coronavirus disease 19 infection GLS-1200 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) GeneOne Life Science Inc US 2020-05-31 2020-11-30 NCT04408183, T2R-002 Phase 2 Clinical Not yet recruiting 1 6 Months 225 Medical Monitor, Project Manager, Rupa Chowdary 2020-06-03
PISCOV: A Clinical trial to study the efficacy of pH based Integrated SARS Cov-2 Immunity in Human Subjects Coronavirus disease 19 infection sunlight exposure alone, Variable regimens including Arsenic album , Chlorpromazine , High pH diet , NBE extract concoction , Tea(Theoxanthine ) Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Siddhartha Hospital India 2020-06-07 CTRI/2020/05/025490, PISCOV, U1111-1252-7438 Phase 2/Phase 3 Clinical Status not specified 1 110 Mr Javed Khan, Sapna Agarwal, Siddharth Agarwal 2020-06-02
The effect of interferon on the treatment of covid19 patients Coronavirus disease 19 infection interferon treatment alone, treatment protocol from the Ministry of Health alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ghoum University of Medical Sciences Iran 2020-03-20 IR.MUQ.REC.1399.089, IRCT20160118026097N3 Phase 3 Clinical Recruiting 1 60 hasan adeli, jamshid vfaeemanesh 2020-06-02
Efficacy and Safety of Ivermectin and Doxycycline in Combination or IVE Alone in Patients With COVID-19 Infection Coronavirus disease 19 infection ivermectin alone, standard care alone, doxycycline hyclate plus ivermectin Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) International Centre For Diarrhoeal Disease Research, Bangladesh Bangladesh 2020-06-30 2020-07-31 NCT04407130, PR-20039 Phase 2 Clinical Not yet recruiting 1 1 Month 72 Wasif Ali Khan, MBBS, MHS, Wasif Ali Khan, MBBS,MHS 2020-06-02
The efficacy of Homeopathic medicines in the prevention of COVID-19 in Quarantined or Exposed Individuals Coronavirus disease 19 infection Variable regimens including Arsenic Album , Bryonia alba , Camphora , Coronavirus related nosodes Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Life Force Foundation Trust India 2020-06-08 CTRI/2020/05/025491 Phase 2 Clinical Not yet recruiting 1 1000 Dr Rajesh Shah 2020-06-02
Epidemiology of Acute Kidney Injury in COVID19 Disease in United Kingdom Coronavirus disease 19 infection, Renal injury Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospitals Of Derby and Burton NHS Foundation Trust UK 2020-06-01 2021-05-21 NCT04407156, UHDB/2020/050 Phase Not Applicable Not yet recruiting 1 11 Months 350 Nitin V Kolhe, MD 2020-06-02
Covid-Simile study: Homeopathy for Covid-19 in primary care Coronavirus disease 19 infection Natrum muriaticum LM2 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundação Universidade Federal De São Carlos, HN-Cristiano Homeopatia South America, Brazil 2020-06-15 2020-12-20 Covid-Simile study, UMIN000040602 Phase 2 Clinical Not yet recruiting 1 6 Months 100 Ubiratan Adler 2020-06-03
A clinical trial of ORP-100S for the treatment of COVID-19 infection Coronavirus disease 19 infection ORP-100 alone Thioredoxin stimulator OrPro Therapeutics Inc Phase Not Applicable Planned 0 2020-06-01
Asymptomatic COVID-19 Coronavirus disease 19 infection Hospital Tengku Ampuan Afzan Malaysia 2020-05-27 2020-06-27 55001, NMRR-20-1050-55001 Phase Not Applicable Status not specified 1 1 Month 100 Dr WONG YEN SHEN 2020-06-03
postICU-COVID19: postICU-COVID19 Coronavirus disease 19 infection, Psychiatric disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Kuala Lumpur Malaysia 2020-05-26 2020-08-31 54967, NMRR-20-1049-54967, postICU-COVID19 Phase Not Applicable Recruiting 1 3 Months 10 Dr Lim Hong Tak 2020-06-03
Clinical clues and management of suspected COVID-19 Coronavirus disease 19 infection Tuanku Jaafar Hospital Malaysia 2020-05-24 2020-05-27 55109, NMRR-20-1045-55109 Phase Not Applicable Completed 1 500 Dr. Poh Kok Wei 2020-06-03
COVID-19 Selangor: COVID-19 Selangor Coronavirus disease 19 infection JABATAN KESIHATAN NEGERI SELANGOR Malaysia 2020-06-01 2020-06-30 54912, C19Sel2020 v1.1, COVID-19 Selangor, NMRR-20-1043-54912 Phase Not Applicable Status not specified 2 1 Month Dr Anita Suleiman 2020-06-03
Evolution of the efficacy and safety of Dexamethasone administration in COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome fluid therapy alone, oxygen therapy alone, dexamethasone (Abouraihan Pharmaceutical Company) plus lopinavir/ritonavir (Hetered Pharmaceutical Company, India) Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shaheed Beheshti Medical University Iran 2020-04-24 IR.SBMU.NRITLD.REC.1399.071, IRCT20151227025726N17 Phase 2/Phase 3 Clinical No longer recruiting 1 48 Farzaneh Dastan, Payam Tabarsi, Seyed Mohammadreza Hashemian, Zahra Mirshafiei Langari 2020-06-04
ILIAD-7-FR: Interleukin-7 to Improve Clinical Outcomes in Lymphopenic patients With COVID-19 Infection FR BL Cohort Coronavirus disease 19 infection, Lymphocytopenia, Respiratory failure CYT-107 alone IL-7 receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) RevImmune SAS France Amarex Clinical Research, University Hospital, Limoges France 2020-06-01 2020-12-30 CLI107 COVID FR (ILIAD-7-FR), ILIAD-7-FR, NCT04407689 Phase 2 Clinical Not yet recruiting 2 6 Months 48 Bruno François, MD, Frederique Berbille, MHSc, Michel Morre, DVM MSc 2020-06-03
COVID-19: IMPROVISE: COVID-19: IMPROVISE Coronavirus disease 19 infection National Institutes of Health Malaysia Malaysia 2020-05-29 2020-07-31 54936, COVID-19: IMPROVISE, NMRR-20-1040-54936 Phase Not Applicable Not yet recruiting 1 2 Months Mr. HING YEE LIANG 2020-06-03
VIVI: Vienna Versus SARS-CoV-2 Virus Study Coronavirus disease 19 infection Healthy volunteers accepted Medical University of Vienna Austria 2020-05-27 2021-06-27 EK 1387/2020, NCT04407429, VIVI Phase Not Applicable Recruiting 2 13 Months 12000 Christian Hengstenberg, Univ.-Prof., Christian Nitsche, Dr., Christoph Binder, Prof., Daniela Gompelmann, Prof., Eva Schernhammer, Prof., Marco Idzko, Prof., Martin Riesenhuber, Dr., Rainer Oberbauer, Prof., Tanja Stamm, Prof., Thomas A Zelniker, DDr., Thomas Perkmann, Dr. 2020-06-03
PEP-Q: Efficacy of Hydroxychloroquine (HCQ) as Post Exposure Prophylaxis (PEP) for Prevention of COVID-19 Coronavirus disease 19 infection home quarantine alone, hydroxychloroquine alone, personal hygiene alone, post exposure prophylaxis alone, social distancing alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Postgraduate Institute of Medical Education and Research India 2020-03-01 2020-06-30 IEC-04/2020-1624, NCT04408456, PEP-Q Phase 3 Clinical Recruiting 1 4 Months 200 Deba P Dhibar, MD, Deba Prasad Dhibar, 2020-06-03
Outpatient Clinic in Obesity Care During COVID-19 Outbreak: Physically Far, Virtually Near Coronavirus disease 19 infection, Obesity Medical counselling alone, Telemedicine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Campania Luigi Vanvitelli Italy 2020-03-03 2020-05-04 NCT04407663, TELEMEDICINE Phase Not Applicable Completed 1 2 Months 138 Claudio Gambardella, Researcher 2020-06-02
Clinical trial study of the therapeutic effect of ivermectin, besides Kaletra and chloroquine in patients with Coronavirus disease 2019 (COVID-19) Coronavirus disease 19 infection Variable regimens including chloroquine , ivermectin , lopinavir + ritonavir Chloride channel modulator, HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ahvaz University of Medical Sciences Iran 2020-05-30 IR.AJUMS.REC.1399.194, IRCT20200422047168N2 Phase 2/Phase 3 Clinical Recruiting 1 60 Ahvaz University of Medical Sciences, Ali akbar Shayesteh, Zahra Shokati 2020-06-02
Stem cell therapy in Covid-19 Coronavirus disease 19 infection, Respiratory distress syndrome allogenic mesenchymal stem cell-derived umbilical cord transplantation alone, other common treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Mashhad University of Medical Sciences Iran 2020-06-14 IR.MUMS.REC.1399.150, IRCT20160809029275N1 Phase 2/Phase 3 Clinical Not yet recruiting 1 20 Dr.Mahnaz Amini, Seyad Jalil Tavakol Afshari 2020-06-02
APRONOX: Awake Prone Positioning and Oxygen Therapy in Patients With COVID-19 Coronavirus disease 19 infection awake prone positioning alone, oxygen therapy alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital General San Juan del Rio Mexico 2020-05-01 2020-07-30 1178/SESEQ-HSGJR/08-05-20/UTI, APRONOX, NCT04407468 Phase Not Applicable Recruiting 6 2 Months 368 Cesar Alonso Bello, MD, Cesar Alonso Bello, MD, MSc, Ernesto Deloya Tomas, MD, Ernesto Deloya Tomas, MD, MSc, Gabiel Cruz Sanchez, MD, Gabriel Cruz Sanchez, MD, Karen P Pozo Cortes, MD, Luis Macias Garcia, MD, Luis Macias, Garcia, Orlando Perez Nieto, MD, Orlando R Perez Nieto, MD 2020-06-02
Effects of licorice in treatment of COVID-19 Coronavirus disease 19 infection hydroxychloroquine sulfate plus licorice Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bandare-abbas University of Medical Sciences Iran 2020-05-21 IR.HUMS.REC.1399.066, IRCT20200506047323N2 Phase 3 Clinical Recruiting 1 60 Mohammad Fathalipour, Parivash Davoodian 2020-06-02
PS-COVID: Peer support training for adolescents during the COVID-19 outbreak Coronavirus disease 19 infection Peer Support Training alone Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs) University of Oxford UK 2020-04-01 2020-07-10 ISRCTN99248812, PS-COVID, R69810/RE001 Phase Not Applicable Recruiting 2 3 Months 100 Dr Pavarini 2020-06-01
A phase II clinical trial of SARS-CoV-2 live-attenuated vaccine for the prevention of COVID-19 infection Coronavirus disease 19 infection COVID-19 vaccine (measles vaccine vector technology), Institut Pasteur/Themis Bioscience/University of Pittsburgh alone Themis Bioscience GmbH Phase 2 Clinical Planned 0 2020-06-01
FALCON-C19: Facilitating AcceLerated Clinical Validation Of Novel Diagnostics for COVID-19 Coronavirus disease 19 infection blood sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Manchester University NHS Foundation Trust 2020-06-01 2021-05-31 B00944, FALCON-C19, NCT04408170 Phase Not Applicable Not yet recruiting 0 12 Months 1000 Eloïse Cook, Richard Body 2020-06-02
Testing the Accuracy of a Digital Test to Diagnose Covid-19 Coronavirus disease 19 infection Covid Symptom Study app, Zoe Global Ltd alone, Covid-19 swab PCR test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) King's College London Department of Health, ZOE Global Ltd Sweden, US, UK 2020-05-28 2021-05-10 COVID-19 VALIDATION STUDY, NCT04407585 Phase Not Applicable Not yet recruiting 4 11 Months 1000000 Andrew Chan, Claire Steves, Inbar Linenberg, MSc, Peter Sasieni, Sarah Berry, Sebastien Ourselin, Tim Spector 2020-06-04
CLAVIS-COVID: Clinical Outcomes of COVID-19 Infection in Hospitalized Patients with Cardiovascular Diseases and/or Risk Factors Cardiovascular disease, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Toho University Japan 2020-06-01 CLAVIS-COVID, UMIN000040598 Phase Not Applicable Not yet recruiting 1 1000 Shigo Matsumoto, Shingo Matsumoto 2020-06-04
A phase I clinical trial of COVID-19 vaccine for the treatment of Coronavirus disease 19 infection Coronavirus disease 19 infection SARS-CoV-2 vaccine (COVID-19), Zolovax alone Endoplasmin modulator Heat Biologics Inc Waisman Clinical Biomanufacturing Facility Phase 1 Clinical Planned 0 2020-06-01
The effect of Stopcivir syrup in patients with COVID-19 Coronavirus disease 19 infection Stopcivir alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Mazandaran University of Medical Sciences Iran 2020-04-05 2020-06-06 IR.MAZUMS.REC.1399.061, IRCT20200411047016N1 Phase 3 Clinical Recruiting 1 2 Months 150 Majid Saeedi, Motahareh Rouhi Ardeshiri, Seyde Sedighe Yousefi 2020-06-02
The analysis of COVID-19 on gastrointestinal endoscopy Coronavirus disease 19 infection gastrointestinal endoscopy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Yokohama City University Japan 2020-06-01 UMIN000040587 Phase Not Applicable Recruiting 1 500 Takuma HIGURASHI 2020-06-05
COVID-SERA: COVID-Serology in Rheumatoid Arthritis (COVID-19) Coronavirus disease 19 infection, Rheumatoid arthritis 2019-nCoV IgM/IgG Diagnostic Test Kit alone, COVID-19 IgG/IgM Rapid Test Kit alone, IgM/IgG Rapid Qualitative Test Kit alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Montpellier France 2020-05-01 2020-09-30 COVID-SERA, NCT04407559, RECHMPL20-0330 Phase Not Applicable No longer recruiting 1 5 Months 216 Rosanna FERREIRA, MD 2020-06-02
GPC: The effect of Guduchi (Tinospora cordifolia) as a prophylactic measure among high risk population (Health Care Workers/Containment Zone Population) exposed to COVID-19 Coronavirus disease 19 infection Guduchi capsule alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Central Council for Research in Ayurvedic Sciences India 2020-06-29 CTRI/2020/05/025485, GPC Phase 2/Phase 3 Clinical Not yet recruiting 1 5000 Dr P V V Prasad 2020-06-02
Efficacy and safety of leflunomide for Refractory novel coronavirus pneumonia (COVID-19): An Open-label Controlled Study Coronavirus disease 19 infection, Viral pneumonia Standard treatment alone, leflunomide alone Dihydroorotate dehydrogenase inhibitor, Protein tyrosine kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Qilu Hospital of Shandong University China 2020-03-12 2020-05-17 ChiCTR2000033372 Phase 0 Clinical Completed 1 2 Months 30 Hu Zhao 2020-06-02
A small clinical trial to study the effects of stem cell therapy on hospitalized COVID-19 patients Coronavirus disease 19 infection stem cell therapy alone Personalized Stem Cells Inc US Phase Not Applicable Planned 1 2020-06-01
IMMUNO-COVID: Study of Kinetics and Efficacy of the Immune Response Against COVID-19 Among Hospital Staff Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Direction Centrale du Service de Sante des Armees France 2020-06-02 2021-06-02 2020-COVID19-04, IMMUNO-COVID, NCT04408001 Phase Not Applicable Not yet recruiting 1 12 Months 800 Damien RICARD, MD, PhD, Jean-Nicolas TOURNIER, MD, PhD 2020-06-02
Development of Smell based test for identifying COVID-19 infection Coronavirus disease 19 infection Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Agri Food Biotechnology Institute India 2020-06-04 CTRI/2020/05/025487 Phase Not Applicable Not yet recruiting 1 300 Dr Mahendra Bishnoi, Sanjay Kumar Bhadada 2020-06-03
COPD in the Time of COVID-19 Chronic obstructive pulmonary disease, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Leicester University Hospitals of Leicester - Leicester Royal Infirmary UK 2020-05-31 2021-06-30 0778, NCT04407598 Phase Not Applicable Not yet recruiting 1 13 Months 350 Hamish J C McAULEY, MBBS, Hamish J C McAuley, MBBS, Neil J Greening, PhD, Omer Elneima, MBBS 2020-06-03
Convalescent Plasma Therapy in Patients With COVID-19 Coronavirus disease 19 infection Convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bio Farma Eijkman Institute for Molecular Biology, Gatot Soebroto Army Center Hospital Indonesia 2020-05-01 2020-08-01 3471041S322342020040800002, NCT04407208 Phase 1 Clinical Recruiting 2 3 Months 10 Familia Bela, Sp.PA, Marliana Sri Rejeki, Sp.FK, Nana Sarnadi, Sp.OG, dr. Marliana Sri Rejeki, Sp.FK 2020-06-03
GGVC19: Clinical study on Guduchi Ghana Vati as a preventive remedy in pandemic of COVID-19 Coronavirus disease 19 infection Guduchi Ghana Vati alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) National Institute of Ayurveda Jaipur Rajasthan India 2020-06-03 CTRI/2020/05/025488, GGVC19, NIA-CVD-19/2020/01 Phase 2/Phase 3 Clinical Not yet recruiting 1 12000 Dr PawanKumar Godatwar, Prof Dr Sanjeev Sharma 2020-06-02
Clinical Study of AT-301(nasal spray,Atossa Genetics Inc) for the treatment of COVID-19 Coronavirus disease 19 infection AT-301(nasal spray,Atossa Genetics Inc) alone Atossa Genetics Inc Phase Not Applicable Planned 0 2020-06-01
The Use of Oxygen Hoods as Compared to Conventional High-flow Oxygen Delivery Systems, the Effects on Oxygenation, Intubation and Mortality Rates in Hypoxic Patients With COVID-19 Coronavirus disease 19 infection, Hypoxia oxygen hood alone Northwell Health Inc US 2020-03-06 2020-05-01 HOODSTUDY701, NCT04407260 Phase Not Applicable Completed 1 1 Month 136 David Dayya, David Dayya, DO, PhD, MPH, Owen J O'Neill, MD, MPH, FUHM 2020-06-02
Evaluation of the Relationship Between Zinc, Vitamin D and B12 Levels in the COVID-19 Positive Pregnant Women Coronavirus disease 19 infection, Hypozincemia, Vitamin D deficiency Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Istanbul Bakirkoy Maternity and Children Diseases Hospital Ibrahim Polat Holding Inc Turkey 2020-04-20 2020-06-03 NCT04407572, ZINC-DVIT-COVID19 Phase Not Applicable No longer recruiting 1 1 Month 45 Pınar Yalcin bahat 2020-06-02
Plasmapheresis and plasma exchanges; usefulness in covid-19 critically ill patients Coronavirus disease 19 infection plasma exchange alone, plasmapheresis alone Children (6-12 yrs), Adolescents (13-17 yrs) Shaheed Beheshti Medical University Iran 2020-03-20 IR.SBMU.NRITLD.REC.1399.016, IRCT20150107020592N23 Phase 2 Clinical Recruiting 1 15 Dr Seyyed Mohamadreza Hashemian, Seyed Mohammad Reza Hashemian 2020-06-02
Sex hormones in coronavirus Coronavirus disease 19 infection Variable regimens including Depo–testosterone , medroxyprogesterone , progesterone Progesterone receptor agonist Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mashhad University of Medical Sciences Iran 2020-05-21 IR.MUMS.REC.1399.192, IRCT20150716023235N15 Phase 2/Phase 3 Clinical Recruiting 1 80 Farahzad Jabbari-Azad 2020-06-04
SILVERBULLET: Efficacy, Safety and Tolerability of Ivermectin in Subjects Infected With SARS-CoV-2 With or Without Symptoms Coronavirus disease 19 infection ivermectin plus paracetamol Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Biomedical Research for the Development of Farmacos S.A. from C.V Mexico 2020-06-30 2020-10-31 NCT04407507, SARS-COV-IVERMX-01, SILVERBULLET Phase 2 Clinical Not yet recruiting 1 4 Months 66 Alma M Perez, MD, Carmen de la Rocha, PhD, Marco A Cid 2020-06-02
Comparison of combination therapies of COVID_19 Coronavirus disease 19 infection atazanavir sulfate + ritonavir (HIV infection), Mylan Laboratories plus hydroxychloroquine HIV protease inhibitor Arak University of Medical Sciences and Health Services Iran 2020-06-20 IR.ARAKMU.REC.1399.006, IRCT20200517047485N1 Phase 3 Clinical Not yet recruiting 1 108 Hossein Mazaherpour 2020-06-04
COVIDiet: Dietary Intake and Eating Habits During the COVID-19 Pandemic Coronavirus disease 19 infection Keenoa app alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) McGill University Canada 2020-05-25 2022-08-31 20-04-064, COVIDiet, NCT04407533 Phase Not Applicable Recruiting 1 27 Months 1920 Stéphanie Chevalier, Stéphanie Chevalier, PhD 2020-06-01
The Relationship Of D-Dimer With Severity And Mortality In SARS-COV-2 Patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Faculty of Medicine Airlangga University Asia 2020-05-10 UMIN000040433 Phase Not Applicable Completed 0 Johanes Nugroho 2020-06-02
CAPTURE: COVID-19: A POC Test Under Research and Evaluation Coronavirus disease 19 infection LumiraDx device alone, LumiraDx platform SARS-CoV-2 assay alone, fingerstick capillary sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Lumiradx UK Ltd UK 2020-04-30 2022-04-30 CAPTURE, NCT04408066, S-CLIN-PROT-00028 Phase Not Applicable Recruiting 3 24 Months 2000 Ben Bloom, Dave Chadwick, Jayne Ellis, Samer Elkhodair, William Niven 2020-06-05
Endothelial Function, Inflammation and Organ Dysfunction in COVID-19 Coronavirus disease 19 infection, Inflammatory disease Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Guy's & St Thomas' Hospital NHS Trust Kings College Hospital NHS Trust UK 2020-06-01 2021-05-31 282930, NCT04408365 Phase Not Applicable Not yet recruiting 1 12 Months 82 Marlies Ostermann, MD, PhD, Nuttha Lumlertgul, MD, PhD 2020-06-02
ACES: Efficacy and Safety of Angiotensin II Use in Coronavirus Disease(COVID)-19 Patients With Acute Respiratory Distress Syndrome Coronavirus disease 19 infection, Respiratory distress syndrome anakinra alone, angiotensin II alone Angiotensin II receptor agonist, Type I IL-1 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Guy's & St Thomas' Hospital NHS Trust Australian and New Zealand Intensive Care Research Centre, Monash University, Royal Surrey County Hospital NHS Trust UK 2020-06-01 2021-05-01 283005, ACES, NCT04408326 Phase Not Applicable Not yet recruiting 1 11 Months 50 Marlies Ostermann, Marlies Ostermann, MD, PhD, Nuttha Lumlertgul, MD, PhD 2020-06-05
Vitamin D Testing and Treatment for COVID 19 Coronavirus disease 19 infection vitamin D3 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Arizona State University Southwest College of Naturopathic Medicine US 2020-05-19 2021-05-18 NCT04407286, STUDY00011960 Phase 1 Clinical Recruiting 1 12 Months 100 James B Adams, PhD, James B. Adams, PhD, Jasmine Kirby, BS, Sarah Trahan, NMD 2020-06-03
CORONA: COVID-19 Research in Organ Transplant Recipients Coronavirus disease 19 infection immunosuppressive treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Vastra Gotaland Region Sweden 2020-06-01 2024-05-01 CORONA, COV-19-SU-TX, NCT04407221 Phase Not Applicable Not yet recruiting 1 47 Months 1100 John M Softeland, MD, PhD, John Mackay Softeland, MD, PhD, Mihai Oltean, MD, PhD, Vanda Friman, MD, PhD 2020-06-03
COVID-OLFA: Diagnostic Value Of Patient-reported And Clinically Verified Olfactory Disorders (COVID-19) Ageusia, Coronavirus disease 19 infection, Dysomia ELISA test alone, RT-PCR test alone, simple olfactory CODA test alone, swabbing alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Montpellier France 2020-03-01 2020-04-30 COVID-OLFA, NCT04407494, RECHMPL20_0176 Phase Not Applicable Completed 1 2 Months 809 Fréderic VENAIL, PU-PH 2020-06-03
QoL and the Emotional-affective Sphere in Rehabilitation Setting During COVID-19 Quarantine Coronavirus disease 19 infection, Musculoskeletal disease, Neurological disease rehabilitation alone, social distancing alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fondazione Don Carlo Gnocchi - Onlus Italy 2020-05-25 2020-08-31 FDG_SOCIALDISTANCING_COVID-19, NCT04408196 Phase Not Applicable Not yet recruiting 1 3 Months 200 IRENE APRILE, MD,PHD, Irene APRILE, MD,PHD 2020-06-03
Seroepidemiological Study of SARS-CoV-2 (COVID-19) Infection in Population Subgroups in the State of Sao Paulo Coronavirus disease 19 infection biological sampling alone, polymerase chain reaction alone, serological test alone Healthy volunteers accepted, Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto Butantan Brazil 2020-06-01 2020-07-30 COVID-19-EPI-01, NCT04408014 Phase Not Applicable Not yet recruiting 1 1 Month 18901 Alexander R Precioso, MD, PhD 2020-06-02
Awake Proning in COVID-19 Patients With Hypoxemic Respiratory Failure Coronavirus disease 19 infection, Hypoxia, Respiratory failure awake prone positioning alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Columbia University US 2020-04-16 2021-05-31 AAAT0134, NCT04408222 Phase Not Applicable No longer recruiting 1 13 Months 29 Sanja Jelic, MD 2020-06-03
Safety and Efficacy of Viusid and Asbrip in Hospitalized Patients Infected by SARS-Cov-2 With COVID-19 Coronavirus disease 19 infection, Respiratory disease, Viral pneumonia standard of care alone, Asbrip plus Viusid Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Catalysis SL Ecuador 2020-05-04 2020-06-15 IESS-HTMC-JUTD-2020-0305-M, NCT04407182 Phase 2 Clinical Recruiting 1 1 Month 60 Mario Mero, Dr, Mario Mero, Dr., Martha Heras Veloz, Martha Heras Veloz, Dr, Martha Heras Veloz, Dr., Wilson Benites I., Dr, Wilson Benites I., Dr. 2020-06-03
A phase II, randomized, double-blind, placebo-controlled trial to evaluate the safety, tolerability, pharmacokinetics and efficacy of OP-101 in patients with severe COVID-19 Coronavirus disease 19 infection OP-101 alone, standard of care alone Orpheris Inc US Phase 2 Clinical Not yet recruiting 1 2020-06-01
SOLID: Study of the Immunity of Patients With Lung Cancer and COVID-19 Infection Coronavirus disease 19 infection, Lung tumor ELISA alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundación GECP Spain 2020-04-15 2020-09-15 GECP 20/04_SOLID, NCT04407143, SOLID Phase Not Applicable Recruiting 66 5 Months 1000 Adriana Rosero, MD, Airam Padilla, MD, Alfonso Gúrpide, MD, Amelia Insa, MD, Ana Blasco, MD, Ana Laura Ortega, MD, Ana López, MD, Ana Reyes, MD, Anna Estival, MD, Antonio Calles, MD, Beatriz Esteban Herrera, MD, Beatriz Esteban, MD, Beatriz Jiménez, MD, Carlos Camps, MD, Carlos García, Carlos García, MD, Clara Gonzálvez, MD, Clara Lucía Gonzálvez, MD, Claudio Ávila, MD, Delvys Rodríguez, MD, Edel del Barco, MD, Ernest Nadal, MD, Esperanza Arriola, MD, Eugenio Palomares, MD, Eva Pereira, Gloria Ma Serrano, MD, Gloria Mª Serrano, MD, Hospital Universitario de Canarias, Hugo Arasanz, MD, Hugo Arazanz, MD, Inmaculada Maestu, MD, Isabel Manrique, MD, Isidoro Barneto, MD, Javier Afonso Afonso, MD, Javier Afonso, MD, Javier Garde, MD, Javier Pérez, MD, Javier de Castro, MD, Jesús Corral, MD, Joaquim Bosch, Joaquim Bosch, MD, Jose García Sánchez, MD, Josefa Terrassa, MD, José García, MD, José Luis López, MD, Juan Coves, Juan Coves, MD, Juan Felipe, MD, Juana Oramas, MD, Judit Rubio, MD, Karmele Areses, MD, Laia Capdevila, MD, Luis Enrique Chara Velarde, MD, Luís Cabezón, MD, MAría González, MD, Ma Pilar Diz, MD, Ma Ángeles Moreno, MD, Manuel Cobo, Manuel Cobo, MD, Manuel Dómine, MD, Manuel Fernández, MD, Margarita Majem, MD, Maria Guirado, MD, Mariano Provencio, MD, Martín Lázaro, MD, María González, MD, María Sereno, MD, Mª Pilar Diz, MD, Mª Ángeles Moreno, MD, Mónica Serrano, MD, Noemí Reguart, MD, Oscar Juan-Vidal, Oscar Juan-Vidal, MD, Rafael López, Rafael López, MD, Raquel Cervera, MD, Reyes Bernabé, Reyes Bernabé, MD, Rosa María Vilaltoro, MD, Rosa María Villatoro, MD, Rosario García, MD, Rubén Alonso Calderón, MD, Rubén Alonso, MD, Santiago Ponce, MD, Sara Cerezo, MD, Sergio Vázquez, MD, Teresa de Portugal, MD, Unai Jiménez, MD, Xabier Mielgo, MD 2020-06-02
COVID-19 and Mental Health Coronavirus disease 19 infection, Psychiatric disorder online survey alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Northeastern University US 2020-06-01 2021-06-01 20-05-22, NCT04407195 Phase Not Applicable Not yet recruiting 1 12 Months 2000 Kara Pavone, Kara Pavone, PhD 2020-06-03
Change in the Ratio of Mean Platelet Volume (MPV) to Platellet(PLT) in Covid-19 Pneumonia Patients Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gaziosmanpasa Taksim Research and Education Hospital Turkey 2020-06-05 2020-08-20 69, NCT04408378 Phase Not Applicable Recruiting 1 2 Months 156 aygen türkmen, MD.prof., zuhal çavuş, MD 2020-06-02
STACOV: Statin Therapy And Covid-19 Infection Coronavirus disease 19 infection statin therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institut Investigacio Sanitaria Pere Virgili Spain 2020-05-14 2020-06-30 106/2020, NCT04407273, STACOV Phase Not Applicable Recruiting 7 1 Month 1200 Lluís Masana, Dr, Luis Masana, MD, PhD 2020-06-02
A clinical study of SARS-CoV-2 vaccine (VLP, COVID-19) for the potential prevention of SARS-CoV-2 infection (COVID-19) Coronavirus disease 19 infection SARS-CoV-2 vaccine (VLP, COVID-19), Medicago alone Medicago Inc US 2020-08-31 Phase Not Applicable Status not specified 1 2020-06-02
CRITICoVid: Prevalence of Critical Forms of CoVid-19 in Patients With Chronic Respiratory Disease Asthma, Bronchus disease, Chronic obstructive pulmonary disease, Coronavirus disease 19 infection, Cystic fibrosis, Dyspnea, Obesity hypoventilation syndrome, Obstructive sleep apnea, Pulmonary hypertension, Respiratory disease Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Hospital, Nancy, France 2020-06-01 2020-08-01 2020PI081, CRITICoVid, NCT04407169 Phase Not Applicable Not yet recruiting 0 2 Months 500 simon valentin, MD 2020-06-02
ANOSIRM: Brain MRI Imaging in Patients With SARS-Cov2 (COVID-19) Infection With or Without Anosmia Coronavirus disease 19 infection, Dysomia brain MRI scan alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire de Nimes France 2020-06-30 2020-12-31 ANOSIRM, NCT04408391, NIMAO/2020-01/BL-001 Phase Not Applicable Not yet recruiting 1 6 Months 40 Anissa Megzari, Benjamin Lallemant, Caroline Alovisetti, Fabricio Pereira, Jean-Paul Beregi, Nicolas Menjot de Champfleur 2020-06-02
Appendicitis During the National Lockdown During the COVID-19 Pandemic Appendicitis, Coronavirus disease 19 infection Lock-down and social distancing alone Nordsjaellands Hospital Denmark 2017-03-23 2020-04-19 APPCOVID-19, NCT04407117 Phase Not Applicable Completed 1 36 Months 6000000 Claus A Bertelsen, PhD 2020-06-02
NR-COVID19: Effects of Nicotinamide Riboside on the Clinical Outcome of Covid-19 in the Elderly Coronavirus disease 19 infection nicotinamide riboside alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) Copenhagen University Bispebjerg Hospital, Elysium Health Inc Denmark 2020-06-01 2022-05-01 H-20026601, NCT04407390, NR-COVID19 Phase 2 Clinical Recruiting 1 23 Months 100 Celeste Porsbjerg, MD/PhD, Morten Scheibye-Knudsen, Morten Scheibye-Knudsen, MD/DMSc(PhD) 2020-06-03
COVIDHELP: COVID-19 in Cancer Patients: Evaluation of Clinical Course and Impact on Oncological Care Including Biobanking Cancer, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitätsklinikum Hamburg-Eppendorf Universitatsklinikum Schleswig-Holstein Campus Kiel, Universitatsklinikum Schleswig-Holstein Campus Lubeck Germany 2020-04-15 2022-04-14 COVIDHELP, NCT04408339, PV7313 Phase Not Applicable Recruiting 2 24 Months 500 Katja Weisel, MD, Niklas Boerschel, MD, S Guengoer 2020-06-02
Role of Children in Transmission of COVID-19 to Immunocompromised Patients Coronavirus disease 19 infection, Immune disorder blood sampling alone, mid-turbinate swab sampling alone, saliva sampling alone Healthy volunteers accepted Jonsson Comprehensive Cancer Center National Cancer Institute US 2020-05-28 2023-05-28 20-000517, NCT04407546 Phase Not Applicable Not yet recruiting 1 36 Months 300 Ashley Gray, M.D., Grace Aldrovandi, M.D. 2020-06-03
Use of Convalescent Plasma for COVID-19 Coronavirus disease 19 infection, Respiratory failure, Tachypnea convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Northside Hospital, Inc. US 2020-06-30 2022-06-30 NCT04408040, NSH 1281 Phase 2 Clinical Not yet recruiting 1 24 Months 700 Kent Holland, MD, Stacey Brown 2020-06-02
AKI Biomarkers in COVID-19 Coronavirus disease 19 infection, Renal injury, Respiratory disease Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Guy's & St Thomas' Hospital NHS Trust University Hospital Muenster UK 2020-06-01 2021-06-30 283675, NCT04408248 Phase Not Applicable Not yet recruiting 1 13 Months 30 Marlies Ostermann, MD, PhD, Nuttha Lumlertgul, MD, PhD 2020-06-02
VANGARD: VIP ANalogue, in hospitalized COVID-19 patients at hiGh risk for rapid clinical deterioration and ARDS Coronavirus disease 19 infection, Respiratory distress syndrome PB-1046 alone VIP 2 receptor agonist PhaseBio Pharmaceuticals Inc US 2020-06-30 COVID19_IMPACT, VANGARD Phase 2 Clinical Not yet recruiting 1 210 2020-06-03
A prospective open-label study of the efficacy and safety of the use of the drug Tigerase as part of complex therapy in patients with COVID-19 Coronavirus disease 19 infection GNR-039 alone Deoxyribonuclease I stimulator CJSC Generium Russian Federation 2020-06-01 2020-11-30 DRN-ALI-III Phase 3 Clinical Status not specified 6 6 Months 150 2020-06-01
Exploratory, open-label study of the efficacy and safety of the use of the drug Elizaria as part of complex therapy in patients with severe and extremely severe COVID-19 course Coronavirus disease 19 infection eculizumab biosimilar, IBC GENERIUM alone Complement C5 factor inhibitor CJSC Generium Russian Federation 2020-06-01 2020-12-31 ECU-ALI-III Phase 3 Clinical Status not specified 7 7 Months 150 2020-06-02
Research study to evaluate the impact of Selected Ayurvedic interventions in containment zone Coronavirus disease 19 infection Guduchi Ghan Vati/ Sudarshan Ghan Vati alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Central Council for Research in Ayurvedic Sciences, Ministry of Ayush India 2020-06-01 CTRI/2020/05/025385 Phase Not Applicable Not yet recruiting 17 40000 Dr Anil Avhad, Dr C Muralikrishna, Dr DSRotwar, Dr Deepa Sharma, Dr K Prameela Devi, Dr Kuldeep, Dr PL Bharati, Dr Paikrao Sumed, Dr Ranjita Ekka, Dr SH Doddamani, Dr Sandip Kumar Ramjivan Baheti, Dr Sanjay Kumar, Dr Savita Sharma, Dr Sneha Marlewar, DrAlok Kumar Srivastava, DrKavita Mansukhbhai Vyas, DrVilas Gangurde, Prof KS Dhiman, SK Vedi, Suhas A Chaudhary, Vipin Sharma 2020-06-01
A study to evaluate the effect and safety of a phytopharmaceutical drug in treatment of Coronavirus infection Coronavirus disease 19 infection purified aqueous extract of Cocculus hirsutus alone Sun Pharmaceutical Industries Ltd India 2020-06-01 CTRI/2020/05/025397, Secondary ID Registry ICR/20/005, Version No. 1.0 Phase 2 Clinical Not yet recruiting 14 210 Dr Amit Dhamija, Dr Apurva Agarwal, Dr Bhattachrya Meenakshi, Dr D Anil Kumar, Dr Harish Gupta, Dr K Vengadakrishnan, Dr Khobragade Akash Ashokkumar, Dr Maulik Doshi, Dr Md Sabah Siddiqui, Dr Parvaiz Koul, Dr Rajadhyaksha Girish Chandrakant, Dr Rakesh Patil, Dr Rohit Parate, Dr Shilpi Dhawan, Dr Shivakumar Sankaranarayanan Iyer, Dr Sushila Kataria, Guruprasad Palekar 2020-06-01
Study to find out the results of Ayurvedic Kwath & Ashwagandha churna with Yoga exercises to prevent our health workers against corona virus infection Coronavirus disease 19 infection Kiratiktadi Kwath & Ashwagandha churna alone, Yoga exercises alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) GS Ayurveda Medical College & Hospital India 2020-05-28 CTRI/2020/05/025398 Phase Not Applicable Not yet recruiting 1 30 Prof Dr Ankur Singhal 2020-06-01
Pregnancy and COVID-19 Registry Coronavirus disease 19 infection Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) ICMR National Institute for Research in Reproductive Health, Medical Education and Drugs Department India CTRI/2020/05/025423 Phase Not Applicable Not yet recruiting 2 2000 Dr Niraj Mahajan, Dr Rahul Gajbhiye, Dr Rakesh Waghmare 2020-06-01
Clinical features and outcome of COVID-19 and non-COVID respiratory infection Coronavirus disease 19 infection, Respiratory tract infection, Viral pneumonia Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) Christian Medical College, Vellore, India India 2020-06-04 CTRI/2020/05/025424 Phase Not Applicable Not yet recruiting 1 100 Leni G Mathew 2020-06-01
Ayurvedic intervention (Chyawanprash) in the prevention of COVID-19 pandemic among Health Care Personnel Coronavirus disease 19 infection Chayavanprash alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Central Council for Research in Ayurvedic Sciences Ministry of Ayush India 2020-06-02 CTRI/2020/05/025425 Phase 4 Clinical Not yet recruiting 1 50 Dr BabitaYadav, Dr Nitin Jindal, Dr Shivshankar Rajput 2020-06-01
SCB-2019 as COVID-19 Vaccine Coronavirus disease 19 infection SCB-2019 alone, Variable regimens including AS03 adjuvant , CpG 1018 adjuvant , SCB-2019 , alum adjuvant Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Clover Biopharmaceuticals AUS Pty Ltd 2020-06-20 2021-03-30 CLO-SCB-2019-001, NCT04405908 Phase 1 Clinical Not yet recruiting 0 9 Months 150 Min Dong 2020-06-01
Clinical Characteristics and Outcomes of Patients Admitted with Severe Acute Respiratory Illness Coronavirus disease 19 infection, Respiratory disease Mazumdar Shaw Medical Foundation India 2020-05-30 CTRI/2020/05/025427 Phase Not Applicable Not yet recruiting 9 200 Amarja Havaldar, Chandan, Dr Murthy, Farookh Khan, Gagan Brar, Jose Chacko, Rajesh Shetty, Shashidhar, Venkatesh Gupta 2020-06-02
A study to find our proportion of Covid 19 cases, need for hospital beds and utility of lockdown at Aurangabad Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Government Medical College, Aurangabad India 2020-06-08 178, CTRI/2020/05/025431 Phase Not Applicable Not yet recruiting 1 300 Dr Jagannath Dixit, Dr Jyoti Iravane, Dr Kananbala Yelikar, Dr Md Ghodke, Dr Mohan Doibale, Dr Smita Andurkar 2020-06-05
CLIPSI study: COVID -19 Pandemic and Lockdown : Impact on Parents Stress level, Infant care and follow-up Acute stress disorder, Coronavirus disease 19 infection Healthy volunteers accepted, Newborn Infants (up to 5 months) Sri Ramachandra Institute of Higher Education and Research India 2020-05-29 CLIPSI study, CTRI/2020/05/025428 Phase Not Applicable Not yet recruiting 1 300 Usha Devi R 2020-06-01
Prediction of Acute Kidney Injury in Patients With COVID-19 Coronavirus disease 19 infection, Renal injury, Respiratory distress syndrome Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Muenster Germany 2020-05-25 2021-03-31 04-ANIT-20, NCT04406688 Phase Not Applicable Not yet recruiting 1 10 Months 300 Alexander Zarbock, MD, Melanie Meersch, MD 2020-06-01
Effect of Ashwagandha (Withania somnifera) as a prophylactic measure among high risk population (Health Care Workers/Containment Zone Population) exposed to COVID-19 Coronavirus disease 19 infection Ashwagandha capsule alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Central Council for Research in Ayurveda and Siddha India 2020-10-06 CTRI/2020/05/025429 Phase 2/Phase 3 Clinical Not yet recruiting 1 5000 Dr PVV Prasad, Dr T Saketh Ram 2020-06-01
To evaluate the safety and tolerability of Cytokine cocktail therapy in healthy volunteers from healthy donors Coronavirus disease 19 infection, Viral infection Cytokine cocktail therapy alone, Interferon-gamma [INF-γ] alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) HealthCare Global Enterprises Ltd, International Stemcell Services Limited India CTRI/2020/05/025432, IMD/CoV/004/2020 Phase 1 Clinical Not yet recruiting 1 6 Dr Ashish Dhoot, Dr Vishal Rao, Meena Dalal 2020-06-03
Evaluation the anti-inflammatory effects of curcumin in the treatment of patients with COVID-19 Coronavirus disease 19 infection common therapeutic protocol alone, nano-curcumin alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ahvaz University of Medical Sciences Iran 2020-06-05 IR.AJUMS.REC.1399.176, IRCT20200519047510N1 Phase 3 Clinical Not yet recruiting 1 60 Ali Asadirad, Mohammad Badavi, Roohangiz Nashibi 2020-06-01
Prevention of Infection and Incidence of COVID-19 in Medical Personnel Assisting Patients With New Coronavirus Disease Coronavirus disease 19 infection bromhexine hydrochloride alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Almazov Federal Center of Heart, Blood and Endocrinology Russian Federation 2020-05-14 2020-09-30 05-20-02-С, NCT04405999 Phase 4 Clinical Recruiting 1 4 Months 140 Evgeny Mikhailov, MD, PhD, Evgeny Shlyakhto, MD, PhD, Tamara Lyubimtseva, MD 2020-06-02
CONFI-LOMB: Confinement Effect on Low Back Pain Intensity in Chronic Low Back Pain Patients Coronavirus disease 19 infection, Lower back pain Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Angers France 2020-06-02 2020-06-21 CONFI-LOMB, CONFI-LOMB, NCT04406363 Phase Not Applicable Not yet recruiting 1 300 Audrey Petit, PhD 2020-06-02
This Study Examines the Use of Disinfectants by Egyptian Women During the Coronavirus Lockdown and How They Seak Medical Advice for Adverse Reactions Related to the Use of Disinfectants Coronavirus disease 19 infection, Toxicity disinfectant usage alone, online survey alone Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Helwan University University of Nebraska Egypt 2020-05-31 2020-07-01 COVID2020_HELWANU_01, NCT04405284 Phase Not Applicable Not yet recruiting 1 1 Month 100 Maha M Farid, PhD, Wael M ElRayes, PhD 2020-06-02
COVADO: Psychological Impact of the Health Measures Generated by the COVID19 in Adolescents Coronavirus disease 19 infection, Psychiatric disorder interview alone Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Centre Hospitalier Intercommunal Creteil France 2020-05-27 2020-11-30 COVADO, COVADO, NCT04406558 Phase Not Applicable Recruiting 1 6 Months 400 Adele CARLIER-GONOD, MD, Camille JUNG, MD PhD 2020-06-02
A study on treatment of COVID-19 patients with study drug along with standard of care Coronavirus disease 19 infection standard of care alone, tocilizumab alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Medanta The Medicity India 2020-05-27 CTRI/2020/05/025369, TCZ/COVID-19/01/2020 Phase 3 Clinical Not yet recruiting 1 180 Dr Arvinder Soin, Dr Pooja Sharma, Kuldeep K Chauhan 2020-06-03
A follow up research of exercise, cardiopulmonary and quality of Life for patients of novel coronavirus pneumonia Coronavirus disease 19 infection pulmonary rehabilitation program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Anhui Provincial Hospital China 2020-05-01 2021-05-20 ChiCTR2000033319 Phase Not Applicable Recruiting 1 12 Months 85 Ming Wu, Yang Zhang 2020-06-02
Evaluation of Role of Ayurvedic Drug- Guduchi Ghan Vati in the treatment of COVID-19 related illness Coronavirus disease 19 infection uduchi Ghan Vati alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Dr.S R.Rajasthan Ayurved University Jodhpur India 2020-06-04 CTRI/2020/05/025370 Phase Not Applicable Not yet recruiting 2 40 DR SANJAY SRIVASTAVA, Prof Dr Abhimanyu Kumar 2020-06-03
ArcHIV - SARS-CoV-2 IgG: Study platform ArcHIV - Substudy on SARS-CoV-2 (COVID-19) IgG antibody prevalence in an HIV cohort Coronavirus disease 19 infection, HIV infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) MUC Research GmbH Lab4More GmbH Germany 2020-05-29 13112 Substudie zu ArcHIV Studienplattform, ArcHIV - SARS-CoV-2 IgG, DRKS00021737, DRKS00021752 Phase Not Applicable Not yet recruiting 1 500 Celia Jonsson-Oldenbüttel, Eva Wolf, Sebastian Noe 2020-06-02
Retrospective Assessment of Treatments of Hospitalized COVID19 Patients Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) ARC Ventures India 2020-06-02 CTRI/2020/05/025371 Phase Not Applicable Not yet recruiting 2 500 Dr Deepa Divekar, Dr Ravindra Ghooi, Dr Sundeep Salvi 2020-06-03
Epidemiological and Clinical Characteristics of 20 Re-positive novel coronavirus pneumonia (COVID-19) Patients Coronavirus disease 19 infection anti-virus treatment alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Affiliated Hospital of Zunyi Medical College The Science and Technology Department of Guizhou Province China 2020-01-29 2020-04-30 ChiCTR2000033347 Phase 1 Clinical No longer recruiting 1 3 Months 20 Zhang Wei 2020-06-01
Erythrocyte Sedimentation Rate in novel coronavirus pneumonia (COVID-19) patients Coronavirus disease 19 infection Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Affiliated Hospital of Zunyi Medical College The Science and Technology Department of Guizhou Province China 2020-02-29 2020-05-12 ChiCTR2000033346 Phase 1 Clinical No longer recruiting 1 2 Months 80 Zhang Wei 2020-06-01
Proof of concept research project to demonstrate the improved transfection by using Nuvec used as a delivery system using a Covid-19 DNA plasmid Coronavirus disease 19 infection Covid-19 DNA plasmid alone, Nuvec alone N4 Pharma plc Phase Not Applicable Status not specified 0 2020-06-01
CA-COVID19: Coagulopathy in COVID19 - A Multicenter, Observational Study in UK (COVID19) Bleeding, Coronavirus disease 19 infection, Thrombosis Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Imperial College London UK 2020-05-21 2021-06-20 20SM5934, CA-COVID19, NCT04405232 Phase Not Applicable Recruiting 1 13 Months 5000 Dr Deepa Jayakody Arachchillage, FRCPath, MD 2020-06-02
Study for the effect of Traditional Chinese medicine in the prevention of novel coronavirus pneumonia (COVID-19) in the high risk area Coronavirus disease 19 infection Chushifangyi prescription alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Affiliated Hospital of Changchun University of Traditional Chinese Medicine China 2020-05-29 2020-12-31 ChiCTR2000033345 Phase Not Applicable Not yet recruiting 1 7 Months 10000 Liu Yangyang, Shi Li 2020-06-01
Efficacy of Liu-zi-jue in Patients with 2019 Novel Coronavirus Pneumonia (COVID-19): a randomized controlled trial Coronavirus disease 19 infection, Viral pneumonia Liu--zi-jue alone, conventional treatment alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shanghai University of Traditional Chinese Medicine, Yueyang Xinhua Pharmaceutical Co Ltd China 2020-02-20 2020-12-30 ChiCTR2000033318 Phase Not Applicable Recruiting 1 10 Months 104 Min Fang, Shuaigpan Zhang 2020-06-01
The Effect of EIDD-2801 on Viral Shedding of SARS-CoV-2 Coronavirus disease 19 infection, Dysomia, Viral pneumonia EIDD-2801 alone RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ridgeback Biotherapeutics LP 2020-05-26 2020-07-13 EIDD-2801-2004, NCT04405739 Phase 2a Clinical Not yet recruiting 0 1 Month 80 Laura Szewczyk 2020-06-01
Clinical Scores for Outcome Prediction in Patients With Severe COVID-19 Pneumonia Requiring ECMO Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia veno-venous extracorporeal membrane oxygenation therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Klinikum der Albert-Ludwigs Universitaet Freiburg Germany 2020-05-19 2020-08-31 EK-FR 329/20, NCT04405973 Phase Not Applicable Recruiting 1 3 Months 100 Alexander Supady, Dr., MPH, Alexander Supady, MD, MPH, Dawid Staudacher, MD 2020-06-02
Determination of Acute Encephalopathy Predictors in Patients With COVID-19 Brain disease, Coronavirus disease 19 infection, Viral pneumonia Blood test alone, Electroencephalography alone, Pulse oximetry alone, chest CT-scan alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Ministry of Health and Social Development of the Russian Federation, Pirogov National Medical Surgical Center Russian Federation 2020-05-22 2020-10-22 NCT04405544, NMSC-01-20 Phase Not Applicable Recruiting 1 5 Months 60 Oleg I Vinogradov, MD, PhD 2020-06-02
COVICLOT: Thromboembolic Events in Severe COVID-19 Patients Coronavirus disease 19 infection, Thromboembolism Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopitaux Universitaires de Strasbourg France 2020-04-29 2021-04-30 7779, COVICLOT, NCT04405869 Phase Not Applicable Recruiting 1 12 Months 300 Alexandre GODON, MD, Alexandre MANSOUR, MD, Anne Claude ROCHE, MD, Anne GODIER, MD, PhD, Annick STEIB, MD, PhD, Bélaïd BOUHEMAD, MD, PhD, Charles TACQUARD, MD, Cécile AUBRON, MD, PhD, Delphine GARRIGUE, MD, Eric KIPNIS, MD, PhD, Isabelle GOUIN-THIBAULT, MD, Julien POISSY, MD, PhD, Lea RYFFEL, MD, Maxime NGUYEN SOENEN, MD, Pierre ALBALADEJO, MD, PhD, Saïd CHAYER, PhD, HDR, Sophie SUSEN, MD, PhD, Stephan MANKIKIAN, MD 2020-06-02
A Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Baicalein in Hospitalized Adult Patients With Mild and Moderate 2019-nCoV Respiratory Disease Coronavirus disease 19 infection Baicoli alone, standard therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chinese Academy of Medical Sciences & Peking Union Medical College, Xiangyang Central Hospital China 2020-02-15 2020-03-09 ChiCTR2000033286 Phase 2/Phase 3 Clinical Completed 2 60 Chaoqing Wang, Xiansheng Zeng 2020-06-01
COZI: COVID-19 Ozanimod Intervention Study Coronavirus disease 19 infection, Hypoxia, Viral pneumonia anticoagulation therapy alone, antipyretics agent therapy alone, antiviral agent therapy alone, corticoid therapy alone, fluid resuscitation alone, immunomodulator therapy alone, ozanimod alone, standard of care alone Sphingosine-1-phosphate receptor-1 agonist, Sphingosine-1-phosphate receptor-5 agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Universite Laval Bristol-Myers Squibb Co, Celgro Corp Canada 2020-07-06 2022-07-06 2021-3474, COZI, NCT04405102 Phase 2 Clinical Not yet recruiting 2 24 Months 48 David Marsolais, PhD, Francois Lellouche, Francois Lellouche, MD, Nathalie Chateauvert, B. pharm, Pascale Blais-Lecours, PhD 2020-06-01
'Pirfenidone XR as a protector in patients with COVID-19' Coronavirus disease 19 infection pirfenidone XR alone Instituto Nacional de Ciencias Medicas y Nutricion Mexico 3381 Phase 3 Clinical Status not specified 1 801 2020-06-01
A clinical trial to evaluate the Medicinal effects of ZingiVir-H as Anti-Viral therapy in COVID-19 patients Coronavirus disease 19 infection NSAID alone, standard of care alone, Variable regimens including HgS and As2S3 , Vitamin C , Zinc , Zingivr-H , oxygen Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Pankajakasthuri Ayurveda Medical College and Post Graduate Center India 2020-05-31 CTRI/2020/05/025434 Phase 4 Clinical Not yet recruiting 3 135 Dr Anita Ajit Saibannavar, Dr Madhukumar, Dr Shan Sasidharan, DrJHareendran Nair, Sri Venkateshwara hospitals 2020-06-03
The comprehensive evaluation of therapeutic drugs for pediatric novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection traditional Chinese medicine alone Children's Hospital of Fudan University China 2020-06-15 2020-11-30 ChiCTR2000033342 Phase Not Applicable Not yet recruiting 12 5 Months 100 Zhiping Li 2020-06-01
IMPACT: Anticoagulation in Critically Ill Patients With COVID-19 Blood clotting disorder, Coronavirus disease 19 infection argatroban alone, enoxaparin sodium alone, fondaparinux sodium alone, unfractionated heparin alone Factor IIa antagonist, Factor Xa antagonist, Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Weill Medical College of Cornell University US 2020-06-30 2021-06-30 20-04021936, IMPACT, NCT04406389 Phase 4 Clinical Not yet recruiting 1 12 Months 186 Maria T DeSancho, MD, MSc, Marina Loizou 2020-06-01
Severe Reluctant COVID-19 Patients Responding to Convalescent Plasma; A case series Coronavirus disease 19 infection convalescent plasma therapy alone Middle-aged Adults (45-64 yrs) University of Sulaimani Iraq 2020-05-11 2020-05-19 ChiCTR2000033323 Phase Not Applicable No longer recruiting 1 24 Fahmi Hussein Kakamad, Rawezh qadr 2020-06-01
The Effectiveness of Telerehabilitation-Based Physiotherapy in COVID 19 Patients Coronavirus disease 19 infection telerehabilitation physical therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Istanbul Medipol University Hospital Saglik bilimleri universtesi Turkey 2020-05-20 2020-12-01 NCT04402983, TELEREHAB_COVID19 Phase Not Applicable Recruiting 1 6 Months 34 Esra Pehlivan, PhD 2020-06-01
Study for Traditional Chinese Medicine in the treatment of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Traditional Chinese Medicine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Shuguang Hospital Shanghai University Of Traditional Chinese Medicine Shanghai Committee of Science and Technology China 2020-03-27 2020-12-31 ChiCTR2000033320, ChiMCTR2000003347 Phase 0 Clinical Recruiting 1 9 Months 300 Zhang Wei 2020-06-01
Viral Specific T-cells for Treatment of COVID-19 Coronavirus disease 19 infection viral specific T-cells alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cincinnati Children's Hospital Medical Center Hoxworth Blood Center US 2020-06-30 2025-06-30 2020-0353, NCT04406064 Phase 2 Clinical Not yet recruiting 1 60 Months 100 Adam Nelson, MBBS, FRACP, Celeste Dourson, MS, Jamie Wilhelm, BS 2020-06-01
Survival and risk factors in COVID-19 and influenza, a retrospective analysis Coronavirus disease 19 infection, Influenza virus infection Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie (DE) Universitat des Saarlandes Germany 2020-05-29 78/20, DRKS00021823 Phase Not Applicable Not yet recruiting 1 18000 Mr. Prof. Dr. Sascha Kreuer 2020-06-01
Home-Based Covid-19 Rehabilitation Program Coronavirus disease 19 infection PT-Pal guided exercise alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Albert Einstein College of Medicine US 2020-07-01 2021-03-01 2020-11535, NCT04406532 Phase Not Applicable Not yet recruiting 1 8 Months 100 Anne F Ambrose, MD, Emmeline Ayers, MPH, Joe Verghese, MBBS 2020-06-01
Stellate Ganglion Block (SGB) for COVID-19 Acute Respiratory Distress Syndrome (ARDS) Coronavirus disease 19 infection, Respiratory distress syndrome Stellate Ganglion Block alone, Variable regimens including bupivacaine, AstraZeneca , dexamethasone , lidocaine Sodium channel inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) West Virginia University US 2020-04-24 2020-12-31 2004963113, NCT04402840 Phase 2 Clinical Recruiting 1 8 Months 5 Ali R Rezai, MD, Ali Rezai, Padma Tirumalai, PhD 2020-06-01
MEMO-COV2: COVID-19: SARS-CoV-2 Specific Memory B and T-CD4+ Cells Coronavirus disease 19 infection blood sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-06-01 2021-03-01 APHP200551, MEMO-COV2, NCT04402892 Phase Not Applicable Not yet recruiting 1 9 Months 60 MAHEVAS Matthieu, PHD 2020-06-01
Psychiatric admissions during the COVID-19 pandemic Coronavirus disease 19 infection, Psychiatric disorder psychological assessment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Prince of Wales Hospital China 2020-05-25 2021-07-31 ChiCTR2000033317 Phase Not Applicable Not yet recruiting 1 14 Months 10000 Allen Ting Chun LEE 2020-06-01
ERap-COV: Evaluation of Rapid Diagnostic Solutions, Serological and Molecular Tests for COVID-19 Coronavirus disease 19 infection ELISA alone, rapid diagnostic test (NG Biotech) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-05-25 2021-03-25 APHP200556, ERap-COV, NCT04405492 Phase Not Applicable Not yet recruiting 2 10 Months 1210 Anne-Marie Roque-Afonso, Thierry Naas 2020-06-01
A clinical study to assess the efficacy of Neumifil in the treatment of patients with COVID-19 infection Coronavirus disease 19 infection Neumifil alone Pneumagen Ltd 2021-06-30 Phase Not Applicable Planned 0 2020-05-29
A multinational, double-blind, randomized, phase II clinical study to assess the effect of ATR-002 in the treatment of COVID-19 patients Coronavirus disease 19 infection ATR-002 alone MEK protein kinase inhibitor Atriva Therapeutics GmbH Evonik Industries AG 2020-07-31 Phase 2 Clinical Planned 0 2020-05-29
CoviPrep Study: TAF/FTC for Pre-exposure Prophylaxis of COVID-19 in Healthcare Workers Coronavirus disease 19 infection emtricitabine + tenofovir alafenamide alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hospital Italiano de Buenos Aires Sociedad Argentina de Infectología Argentina 2020-06-15 2020-11-15 16052020, CoviPrep Study, NCT04405271 Phase 3 Clinical Not yet recruiting 1 5 Months 1378 Diego H Giunta, PhD, Elvira Zini, MD, Esteban Nannini, MD, Fernando Riera, MD, Gonzalo Corral, MD, Gustavo Costilla Campero, MD, Gustavo D Lopardo, MD, Marcelo Figueiras, MD, Omar Sued, MD, Santiago Ramirez Borga, MD, Ventura Simonovich, MD, Waldo H Belloso, MD, Wanda Cornistein, MD 2020-06-01
Study on the improvement the quality of life of severe patients with COVID-19 by the integrated treatment with Chinese medicine and Western medicine Coronavirus disease 19 infection chinese herbal medication alone, pirfenidone alone, traPirfenidone alone, traditional Chinese Medicine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Guangzhou Women and Children's Medical China 2020-06-01 2025-05-31 ChiCTR2000033284 Phase 0 Clinical Not yet recruiting 2 60 Months Zhang Shunxian 2020-06-01
Study of the Spread of COVID-19 in Saint Petersburg, Russia Coronavirus disease 19 infection SARS-CoV-2-specific antibodies test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) European University at St. Petersburg Clinic “Scandinavia” (LLC Ava-Peter) Russian Federation 2020-05-27 2020-10-28 CDRU-001, ISRCTN11060415, NCT04406038 Phase Not Applicable Recruiting 1 5 Months 1550 Anton Barchuk, MD, Daniil Shirokov, Dr Dmitriy Skougarevskiy, Lubov Barabanova, MD 2020-06-02
Monitoring COVID-19 Patients' Lung Fluid Using Impedance Technique Coronavirus disease 19 infection lung impedance technique alone, x-ray alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hillel Yaffe Medical Center Israel 2020-04-28 2021-04-28 0059-20-HYMC, NCT04406493 Phase Not Applicable Recruiting 1 12 Months 50 Michael Cleiner, M.D, Michael Cleiner, M.D. 2020-06-01
CPC-SARS: Convalescent Plasma of Covid-19 to Treat SARS-COV-2 a Randomized, Doble-Blind, Two-Center Trial Coronavirus disease 19 infection, Hypoxia, Viral pneumonia Variable regimens including azithromycin , convalescent plasma , hydroxychloroquine Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hospital General Naval de Alta Especialidad Instituto Nacional de Enfermedades Respiratorias, National Institute of Pediatrics Mexico 2020-05-20 2020-07-20 CPC-SARS, DI/20/201/04/19, NCT04405310 Phase 2/Phase 3 Clinical Recruiting 2 2 Months 80 AMALIA BRAVO-LINDORO, MS, ANGEL A PEREZ-CALATAYUD, MD, ANGEL AUGUSTO PEREZ-CALATAYUD, MD, Angel Augusto Perez Calatayud, BALTAZAR PECH-ALONSO, MD, CARLOS CABELLO-GUTIERREZ, PHD, CARLOS PEÑA-PEREZ, MD, CATALINA CASILLAS-SUAREZ, PHD, EVELYN CORTINA-DE LA ROSA, MS, JOSE CARRILLO RUIZ, PhD, KARLA MALDONADO-SILVA, MD, ORLANDO CARILLO-TORRES, PHD, ORLANDO CARRILLO-TORRES, PHD, RAUL CARRILLO-ESPER, MD, SANDRA MURRIETA, MD, VERONICA FERNANDEZ-SANCHEZ, PHD, YANET VENTURA, MD, YANET VENTURA-ENRIQUEZ, MD 2020-06-01
Efficacy of Ivermectin in Adult Patients With Early Stages of COVID-19 Coronavirus disease 19 infection ivermectin alone Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centro de Estudios en Infectogía Pediatrica Colombia 2020-06-30 2020-11-01 NCT04405843, SCDI823 Phase 2/Phase 3 Clinical Not yet recruiting 1 4 Months 400 2020-06-01
Muscle Mass and Strength as Predictors of Time to Discharge in Patients With COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Sao Paulo Brazil 2020-05-23 2022-05-23 31303720.7.0000.0068, NCT04406233 Phase Not Applicable Recruiting 1 24 Months 176 Bruno Gualano, Phd 2020-06-01
Prospective, observational study on cytokine removal effect of continuous hemodiafiltration in COVID-19 Coronavirus disease 19 infection continuous hemodiafiltration alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Juntendo University Japan 2020-05-18 UMIN000040563 Phase Not Applicable Recruiting 1 20 Junichiro Nakata 2020-06-01
Co-SURVIVORS: COVID-19: Respiratory and Sleep Follow-up Coronavirus disease 19 infection, Post traumatic stress disorder, Sleep disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Grenoble France 2020-06-05 2026-03-05 38RC20.157, Co-SURVIVORS, NCT04406324 Phase Not Applicable Not yet recruiting 4 69 Months 400 Anne-Laure Mounayar, MD, Bruno Chenuel, MD, Pr, Carole Planes, MD, Pr, Genevieve Derumeaux, MD, Pr, Jean-Louis Pepin, MD, Pr, PhD, Marie Destors, MD, Nicolas Terzi, MD, Pr, Renaud Tamisier, MD, PhD, MBA, Renaud Tamisier, MD, Pr, PhD, Sam Bayat, MD, Pr, PhD 2020-06-01
Microvascular Flow and Reactivity in Patients Presenting in the Acute Phase of COVID-19 Cardiovascular disease, Coronavirus disease 19 infection skin laser Doppler perfusion monitoring alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto Nacional de Cardiologia Brazil 2020-05-15 2020-11-30 #CAAE 31237220.1.0000.5272, NCT04406545 Phase Not Applicable Recruiting 1 6 Months 25 Eduardo Tibirica, Eduardo Tibirica, MD, PhD 2020-06-02
A Study to Assess the Feasibility of Screening for SARS-CoV-2 Among Healthy Workers Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Miltenyi Biotec B.V. & Co. KG Germany 2020-04-22 2021-01-31 M-2020-360, NCT04405466 Phase Not Applicable Recruiting 1 9 Months 500 Barbara von Ingersleben, Dr., Sandra Karitzky, Dr. 2020-06-01
REMDACTA: A Study to Evaluate the Efficacy and Safety of Remdesivir Plus Tocilizumab Compared With Remdesivir Plus Placebo in Hospitalized Participants With Severe COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia standard of care alone, remdesivir plus tocilizumab (intravenous), Roche/Chugai COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, IL-6 receptor antagonist, IL-6 receptor modulator, RNA polymerase modulator Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Genentech Inc, Roche Holding AG Gilead Sciences Inc Canada, Europe, US 2020-05-31 2020-07-31 2020-002275-34, NCT04409262, REMDACTA, WA42511 Phase 3 Clinical Not yet recruiting 9 2 Months 450 Clinical Trials 2020-06-02
ET-COVID-19: Endovascular Thrombectomy in COVID-19 Infected Patients Coronavirus disease 19 infection, Ischemic stroke mechanical thrombectomy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Montpellier France 2020-04-01 2020-06-30 ET-COVID-19, NCT04406090, RECHMPL20_0322 Phase Not Applicable Recruiting 1 3 Months 50 Federico Cagnazzo, MD, Federico Cagnazzo, MD PhD, Vincent COSTALAT, PhD, MD, MSc 2020-06-01
QUARCOPSY: Consequences of the QUARANTINE Relating to the Covid-19 Epidemic on the Mental Health of the Patients Followed in Psychiatry Anxiety disorder, Coronavirus disease 19 infection, Mood disorder, Personality disorder, Post traumatic stress disorder, Psychotic disorder, Somatoform disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Regional Universitaire de Lille 2020-05-31 2021-05-31 2020-A01186-33, 2020_39, NCT04405362, QUARCOPSY Phase Not Applicable Not yet recruiting 0 12 Months 753 Arnaud Leroy, MD 2020-06-01
The Impact of quarantine and social distancing on mental health in the context of the Covid-19 pandemic Coronavirus disease 19 infection, Psychiatric disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Eberhard Karls Universität Tübingen Germany 2020-04-08 A2.5.4-120_kr, DRKS00021791 Phase Not Applicable No longer recruiting 1 Sebastian Wolf 2020-06-01
Prevention of Coronavirus Disease (COVID-19) Outbreaks With Nitazoxanide Coronavirus disease 19 infection nitazoxanide alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Materno-Perinatal Hospital of the State of Mexico Laboratorios Liomont Sa De Cv Mexico 2020-05-21 2020-12-31 2020-04-682, NCT04406246 Phase 4 Clinical Recruiting 1 7 Months 150 Hugo Mendieta Zeron, PhD, Hugo Mendieta Zerón, MD., PhD., José Meneses Calderón, MD, José Meneses Calderón, MD., Marlen Santamaría Benhumea, PhD., Nancy Santamaría Benhumea, Bachelor in Law 2020-06-01
PACTT: Hydroxychloroquine, Azithromycin in the Treatment of Covid-19 Coronavirus disease 19 infection, Viral pneumonia standard of care alone, azithromycin plus hydroxychloroquine Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Farhat Hached University Hospital Tunisia 2020-07-31 2021-03-31 NCT04405921, PACTT, PACTT Phase 3 Clinical Not yet recruiting 1 8 Months 200 Amel Letaief, Amel Letaief, Professor 2020-06-05
Covid-HUS: Clinical, Biological and Genetic Prognostic Factors for SARS-CoV-2 Infection in Patients Hospitalized in Strasbourg Coronavirus disease 19 infection Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopitaux Universitaires de Strasbourg France 2020-03-27 2022-03-31 7760, Covid-HUS, NCT04405726 Phase Not Applicable Recruiting 1 24 Months 500 Aurélie VELAY, MD, Eric SOULIER, InG, Floriane GALLAIS, MD, François DANION, MD, Héloïse DELAGREVERIE, MD, Ilies BENOTMANE, MD, Morgane SOLIS, MD, Nicolas LEFEBVRE, MD, Nicolas MEYER, MD, PhD, Samira FAFI-KREMER, PharmD, PhD, Saïd CHAYER, PhD, HDR, Yves HANSMANN, MD, Yvon RUCH, MD 2020-06-02
A global, multicenter, randomized, double-blinded, placebo-controlled trial to assess the efficacy, safety and tolerability of LYT-100 in non-critical COVID-19 patients with respiratory complications Coronavirus disease 19 infection, Fibrosis, Inflammatory disease, Respiratory disease deupirfenidone alone PDGF receptor antagonist, TGF beta receptor antagonist, p38 MAP kinase inhibitor PureTech Health Plc 2020-09-23 Phase Not Applicable Planned 0 150 2020-05-29
CAPANCOVID-19: Reorganization of the Healthcare System During COVID-19 Pandemic: Impact on Management of Patients With Exocrine Pancreatic Cancer Adenocarcinoma, Coronavirus disease 19 infection, Pancreas tumor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire de Reims France 2020-04-01 2022-04-30 CAPANCOVID-19, NCT04406571, PO20042 Phase Not Applicable Recruiting 1 25 Months 700 Olivier BOUCHE 2020-06-01
Investigating the efficacy of Provita Capsule in controlling the symptoms of patients with COVID-19 Coronavirus disease 19 infection, Cough, Dyspnea, Fever Provita alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Bagheiat-allah University of Medical Sciences, TAK GENE ZIST Baqiyatallah University of Medical Sciences Iran 2020-05-14 IR.BMSU.REC.1399.124, IRCT20080901001165N60 Phase 3 Clinical Recruiting 1 30 Gholamhosein Alishiri, Maryam Tajabadi, Mostafa Ghanei, Parisa Kianpour, Seyed Hasan Saadat, Yunes Panahi 2020-06-01
Dose-Confirmation Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1273 COVID-19 Vaccine in Adults Aged >/= 18 Years Coronavirus disease 19 infection mRNA-1273 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) ModeRNA Therapeutics Biomedical Advanced Research and Development Authority (BARDA), US Department of Health and Human Services US 2020-05-25 2021-08-31 75A50120C00034, MRNA-1273-P201, NCT04405076 Phase 2a Clinical Recruiting 10 15 Months 600 Moderna Clinical Trials 2020-06-01
A Safety, Tolerability and Efficacy of EIDD-2801 to Eliminate Infectious Virus Detection in Persons With COVID-19 Coronavirus disease 19 infection EIDD-2801 alone RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ridgeback Biotherapeutics LP US 2020-05-26 2020-07-13 EIDD-2801-2003, NCT04405570 Phase 2a Clinical Not yet recruiting 1 1 Month 44 Laura Szewczyk, Susan Pedersen, William Fischer 2020-06-01
IMPACT SMI-COVID-19 Survey: Investigating the impact of COVID-19 and its response, on people with severe mental illness in South Asia Bipolar disorder, Coronavirus disease 19 infection, Depression, Schizoaffective disorder, Schizophrenia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of York National Institute for Health Research (NIHR) Pakistan, Bangladesh, India 2020-04-10 2022-02-01 IMPACT SMI-COVID-19 Survey, ISRCTN15571919, NIL KNOWN Phase Not Applicable Recruiting 6 21 Months 2000 Dr Zavala 2020-06-01
Multi-site audit of COVID-19 airway interventions Coronavirus disease 19 infection airway intervention alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) St Vincents Hospital Sydney Ltd Australia 2020-04-30 2021-03-27 ACTRN12620000617965 Phase Not Applicable Recruiting 1 10 Months 100 Dr Erez Ben-Menachem 2020-06-01
In a simulation environment, is there a difference in time taken for consultant anesthetists to perform spinal anaesthesia as compared to general anesthesia on women, with suspected or confirmed COVID-19, who require emergency cesarean delivery? Coronavirus disease 19 infection general anesthesia simulation alone, spinal anesthesia simulation alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mackay Base Hospital Australia 2020-05-20 2020-06-01 ACTRN12620000579998, U1111-1251-9551 Phase Not Applicable Not yet recruiting 1 10 Dr Marcelo Epsztein Kanczuk 2020-06-01
TROCAR: Tocilizumab for treatment Of COVID-19 in intensive care patients Coronavirus disease 19 infection tocilizumab (intravenous), Roche/Chugai alone IL-6 receptor antagonist, IL-6 receptor modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Queensland Institute of Medical Research Australia 2020-05-26 ACTRN12620000580976, TROCAR Phase 1/Phase 2 Clinical Not yet recruiting 4 150 A/Prof Bridget Barber 2020-06-01
Post-Intensive Care Nutrition Status in Patients with COVID-19 Coronavirus disease 19 infection, Malnutrition Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Australian and New Zealand Intensive Care Research Centre Australia 2020-05-29 ACTRN12620000602921 Phase Not Applicable Not yet recruiting 9 200 Dr Emma Ridley 2020-06-01
Covid-19 Biobank of clinical samples and data for use in research to help understand the immune characteristics of people who are diagnosed with COVID19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Alfred Health Lord Mayor's Charitable Foundation Australia 2020-04-16 ACTRN12620000609954, U1111-1252-1632 Phase Not Applicable Recruiting 6 250 Dr James McMahon, Ms Janine Roney 2020-06-01
A clinical study performance of the SARS-CoV-2 ELISA Kit was compared with a molecular diagnosis (PCR) using serum samples Coronavirus disease 19 infection SARS-CoV-2 ELISA Kit alone Enzo Biochem Inc Phase Not Applicable Status not specified 0 150 2020-06-01
The MEND Trial: The MEND (MEseNchymal coviD-19) Trial: a pilot study to investigate early efficacy of mesenchymal stem cells in adults with COVID-19 Coronavirus disease 19 infection mesenchymoangioblast-derived mesenchymal stem cell therapy (Cymerus, critical limb ischemia/graft versus host disease/asthma/diabetic foot ulcer), Cynata/FUJIFILM alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cynata Therapeutics Ltd Cerebral Palsy Alliance Research Foundation Australia 2020-06-01 ACTRN12620000612910, The MEND Trial Phase 1/Phase 2 Clinical Not yet recruiting 2 24 A/Prof Vineet Nayyar, Dr Kilian Kelly, Dr Madison Paton 2020-06-01
Validation of COVID-19 Tests Coronavirus disease 19 infection RAPG-COV-019 test kit membrane-based immunoassay alone, quantitative IgG test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Richmond Pharmacology Limited UK 2020-03-16 2020-08-31 C20010, NCT04404062 Phase Not Applicable No longer recruiting 1 5 Months 500 Jorg Taubel, MD 2020-06-02
COVIT-D: Increased Risk of Severe Coronavirus Disease 2019 Infection in Patients With Vitamin D Deficiency Coronavirus disease 19 infection, Vitamin D deficiency Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Clinico San Carlos Spain 2020-04-17 2020-07-01 20/428-E_COVID, COVIT-D, NCT04403932 Phase Not Applicable Recruiting 1 2 Months 500 Fernando Macaya, Francisco J Martín, MD PhD 2020-06-02
A proof-of-concept clinical study to assess whether the Prototype Polygenic Risk Score would differentiate COVID-19 patients who required hospitalization from those who did not require hospitalization Coronavirus disease 19 infection Prototype Polygenic Risk Score alone Genetic Technologies Ltd Phase Not Applicable Status not specified 0 1500 2020-05-29
COVID-PSL: Observational Study in Diagnosed Patients COVID-19, Supported on an Outpatient Basis Coronavirus disease 19 infection telephone consultation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre de Recherches et d'Etude sur la Pathologie Tropicale et le Sida France 2020-06-15 2020-08-15 COVID-PSL, CREPATS 011, NCT04402905 Phase Not Applicable Not yet recruiting 1 2 Months 450 Christine Katlama, MD, Yasmine Dudoit 2020-06-02
IONIC: IMU-838 and Oseltamivir in treatment of Novel Coronavirus (COVID-19) Coronavirus disease 19 infection standard care alone, oseltamivir plus vidofludimus Dihydroorotate dehydrogenase inhibitor, Exo-alpha sialidase inhibitor, IL-17 antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospitals Coventry & Warwickshire NHS Trust UK 2020-05-15 2020-001805-21, IONIC, RA486120 Phase 2 Clinical Recruiting 1 120 Kavi Sharma 2020-06-02
Investigating the efficacy and safety of Niwasha mouthwash in controlling the symptoms of patients with COVID-19 Coronavirus disease 19 infection Niwasha mouthwash alone, routine treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Baqiyatallah University of Medical Sciences Iran 2020-05-25 IRCT20080901001165N59, ir.bmsu.rec.1399.021 Phase 3 Clinical Recruiting 1 80 Ali Ghazivini, Dr. Ghahreman, Mohammad Rezapour, Parisa Kianpour, Yunes Panahi 2020-06-02
Investigating the efficacy and safety of Plasmapheresis in patients with Moderate to severe COVID-19 Coronavirus disease 19 infection, Viral pneumonia Plasmapheresis alone, Routine treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bagheiat-allah University of Medical Sciences Iran 2020-04-29 IR.BMSU.REC.1399.119, IRCT20080901001165N58 Phase Not Applicable Recruiting 1 100 Behzad Einollahi, Gholamhosein Alishiri, Mohammad Rezapour, Parisa Kianpour, Yunes Panahi 2020-05-29
IgG/IgM Antibody Test in Patients Who Have Tested Negative or Positive for COVID-19 With Nasopharyngeal PCR Testing Coronavirus disease 19 infection SARS-Cov2 virus IgG/IgM Clungene rapid test cassette alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sharp HealthCare US 2020-05-05 2020-12-01 2005801, IGG/IGM COVID19, NCT04402814 Phase Not Applicable Recruiting 3 6 Months 60 Divina Fanning, RN, Fadi Haddad, MD, Kathryn Miller 2020-05-29
Pembrolizumab (CinnaGen Co, Iran) in COVID-19 Coronavirus disease 19 infection Standard of care alone, pembrolizumab, CinnaGen alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) CinnaGen Co Iran 2020-06-06 IR.SBMU.NRITLD.REC.1399.117, IRCT20150303021315N19 Phase 2 Clinical Not yet recruiting 2 62 Alireza Rezvani, Nasim Anjidani, Payam Tabarsi 2020-05-29
Endotoxin and circulating bacteriome in severe COVID-19 patients Coronavirus disease 19 infection, Sepsis, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chulalongkorn University Thailand 2020-03-13 TCTR20200527001 Phase Not Applicable Completed 1 19 Nattachai Srisawat 2020-06-02
Egyptian Doctors Stresses, Knowledge and Attitude During COVID-19 Pandemic Acute stress disorder, Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Ain Shams University Egypt 2020-05-31 2020-06-30 EGYPTIAN DOCTORS IN COVID-19, NCT04403581 Phase Not Applicable Not yet recruiting 1 1 Month 384 Riham H Raafat, MD 2020-05-29
Impact of COVID-19 on Personal Protection Among Dentist in Egypt Coronavirus disease 19 infection online survey alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Fayoum University, EG Egypt 2020-05-20 2020-06-15 NCT04403828, PPE IN COVID-19 Phase Not Applicable Recruiting 1 300 Aliaa I Mahroun, PhD, Aliaa I Mahrous, PhD, Alshaimaa A Shabaan, PhD, Alshaimaa Ahmed shabaan 2020-06-02
Convalescent Plasma Therapy in Severe COVID-19 Infection Coronavirus disease 19 infection, Respiratory distress syndrome antibiotic therapy alone, fluid therapy alone, steroid therapy alone, Variable regimens including apheretic convalescent plasma , enoxaparin sodium , favipiravir , lopinavir + ritonavir , oxygen , remdesivir COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, HIV protease inhibitor, Low molecular weight heparin, RNA polymerase inhibitor, RNA polymerase modulator Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bangabandhu Sheikh Mujib Medical University Dhaka medical college Bangladesh 2020-05-20 2020-10-30 BSMMU/2020/6104, NCT04403477 Phase 2 Clinical Recruiting 1 5 Months 20 Fazle R Chowdhury, FCPS, PhD, Fazle R Chowdhury, FCPS, PhD, Fazle Rabbi Chowdhury, Mohammad S Rahman, MPhil,FCPS, Mohammad S Rahman, MPhil, FCPS, Sayedur Rahman, MPhil, FCPS 2020-05-28
Covid-Immun: The role of immune-reactions in patients with COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Heidelberg Germany 2020-03-18 Covid-Immun, DRKS00021810, S-148/2020 Phase Not Applicable Recruiting 1 1000 Uta Merle 2020-05-29
A clinical study of convalescent plasma therapy in patients hospitalized with COVID-19 Coronavirus disease 19 infection convalescent plasma therapy alone Mount Sinai Hospital Canada Phase Not Applicable Status not specified 1 39 2020-06-01
Characterizing SARS-CoV-2-specific Immunity in Individuals Who Have Recovered From COVID-19 Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) HIV Vaccine Trials Network HIV Prevention Trials Network, National Institute of Allergy and Infectious Diseases Peru, US 2020-05-13 2021-08-31 5UM1AI068614-14, HVTN 405/HPTN 1901, NCT04403880 Phase Not Applicable Recruiting 27 15 Months 400 CRS Coodinator, CRS Coordinator, CRS Coorindator, CRS Leader, Clinical Trial Manager, E CRS Coordinator, Fernando Roman, Larry Corey, Protocol Team Leader, Shelly Karuna 2020-05-30
SOCRATES: Somerset and South Essex Coronavirus Antigen Testing Coronavirus disease 19 infection PCL COVID-19 Ag rapid FIA test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Somerset NHS Foundation Trust UK 2020-06-30 2021-08-31 IRAS283137, NCT04403906, SOCRATES Phase Not Applicable Not yet recruiting 1 14 Months 200 Caitlin Morgan, MBBS, Justin Pepperell, MD 2020-05-28
A clinical, double-blind, randomized study to assess the effects and safety of Ivermectin in patients with Severe Acute Respiratory Syndrome during the Covid-19 pandemic Coronavirus disease 19 infection, Respiratory distress syndrome ivermectin alone, Variable regimens including amoxicillin/clavulanate , azithromycin , oseltamivir Chloride channel modulator, Exo-alpha sialidase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Faculdade de Medicina de São José do Rio Preto, Hospital de Base de São José do Rio Preto Brazil 2020-05-01 30899920.5.1001.5415, 4.031.618, RBR-7hzhwd, U1111-1250-6724 Phase 2b Clinical Recruiting 1 566 Suzana Margareth Lobo 2020-06-02
Convalescent plasma to limit COVID-19 associated complications Coronavirus disease 19 infection Convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Yale University Albert Einstein College of Medicine, NYU Langone Health 2020-05-31 2023-01-31 2000028181, NCT04404634 Phase 2 Clinical Not yet recruiting 0 32 Months 300 Alessandro Santin, MD, Mahalia Desruisseaux, MD 2020-05-29
Comparative assessment of the efficacy and safety of addon treatment with 'Sofosbuvir-Daclatasvir', 'Lithium',and 'Trifluoprazine' to 'standard of care' in three groups of patients with COVID-19 Coronavirus disease 19 infection hydroxychloroquine alone, Variable regimens including Sofosbuvir + Daclatasvir , hydroxychloroquine , lithium , trifluoperazine , trihexyphenidyl Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kermanshah University of Medical Sciences Iran 2020-04-08 IR.KUMS.REC.1399.063, IRCT20130812014333N147 Phase 3 Clinical Recruiting 1 80 Dr. Babak Sayad, Dr. Reza Khodarahmi, Feizollah Foroughi, habibolah khzaei 2020-05-28
DORNASESARS2: Dornase Alfa for ARDS in Patients With SARS-CoV-2 Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure dornase alfa alone, standard of care alone Deoxyribonuclease I stimulator, Deoxyribonuclease stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Missouri US 2020-05-30 2022-05-31 2022206, DORNASESARS2, NCT04402970 Phase 3 Clinical Recruiting 1 24 Months 20 Mohammed Alnijoumi, MD, Zach Holliday, MD, Zachary M Holliday, MD 2020-06-05
S3-study: Sero-surveillance SARS-CoV-2 Coronavirus disease 19 infection Serologic surveillance alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Amsterdam UMC Netherlands 2020-03-23 2020-12-31 NL8645, S3-study Phase Not Applicable Recruiting 1 9 Months 800 Jonne Sikkens 2020-05-28
COV-PLAS: A randomized, double blinded clinical trial of convalescent plasma compared to standard plasma for treatment of hospitalized non-ICU patients with COVID-19 infections Coronavirus disease 19 infection convalescent thawed fresh frozen plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Leiden University Medical Center Netherlands 2020-05-31 2021-05-01 COV-PLAS, NL8633 Phase 2/Phase 3 Clinical Recruiting 1 11 Months 430 Jaap Jan Zwaginga 2020-05-28
Ivermectin and Doxycycine in COVID-19 Treatment Coronavirus disease 19 infection doxycycline hyclate plus ivermectin (Iverzine) Tanta University Egypt 2020-06-01 2030-12-03 NCT04403555, TANTA COMBO COVID TREATMENT Phase 2/Phase 3 Clinical Not yet recruiting 1 126 Months 40 Sherief Abd-Elsalam, ass. prof., sherief Abd-Elsalam, Ass. Prof. 2020-05-28
The safety and efficacy of STC-3141 in patient with COVID-19 Acute Respiratory Distress Syndrome Coronavirus disease 19 infection, Respiratory distress syndrome STC-3141 alone Histone inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Grand Medical Pty Ltd Australia 2020-05-29 ACTRN12620000588998 Phase 2 Clinical Not yet recruiting 1 160 Dr Marcel Tanudji, Prof Anders Aneman 2020-06-04
Familial Mediterranean Fever and Behcet: Analysis Before and After COVID-19 Pandemic Behcets disease, Coronavirus disease 19 infection, Familial mediterranean fever Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Istanbul University Turkey 2020-04-01 2020-06-15 10840098-604.01.01-E.14697, NCT04403438 Phase Not Applicable Recruiting 1 2 Months 45 Nejla Uzun, MSc, Pt 2020-05-28
CoVEX: Different Susceptibility to SARS CoV-2 Infection Among Health Care Workers Highly Exposed to COVID-19 Coronavirus disease 19 infection Flow cytometry alone, PCR test alone, RT-PCR test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Asociacion para el Estudio de las Enfermedades Infecciosas Spain 2020-06-01 2020-09-30 CoVEX, EC, EC 162/20, NCT04402827 Phase Not Applicable Recruiting 1 4 Months 60 Alejandro Vallejo, MD, PhD, Amaranta McGee, MD, Ana Moreno, MD, Carmen Quereda, MD, Elisabeth Sanchez, MD, Jose L Casado, MD, PhD, Jose L Casado, Md, PhD, Pilar Vizcarra, MD 2020-06-01
Convalescent Plasma treatment trial in COVID 19 patients Coronavirus disease 19 infection Convalescent Plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Wockhardt Ltd India 2020-06-01 CTRI/2020/05/025299, WH-CP-02-21 Phase 2 Clinical Not yet recruiting 1 20 Dr AjayKumar R Yadav, Dr Ashima Bhatia, Dr Behram Shawak Pardiwalla 2020-06-02
Survey of Mouth-dissolving Turmeric Lozenges in Healthcare Workers Coronavirus disease 19 infection Trumgel alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Gelnova Laboratories (India) Pvt Ltd India 2020-05-26 CTRI/2020/05/025317 Phase 4 Clinical Not yet recruiting 1 300 DR MANJUSHA RAJARSHI, Dr Niharika Gill 2020-06-02
TRANSCOVID: Study of Viral Load and Maternal-fetal Serology in the Interpretation of the Vertical Transmission of SARS Cov-2 (COVID-19) During Pregnancy Coronavirus disease 19 infection nasopharyngeal aspiration alone, nasopharyngeal swab sampling alone, placenta swab sampling alone, serology alone, vaginal swab sampling alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital of Besancon France 2020-05-17 2020-12-31 2020/500, NCT04402918, TRANSCOVID Phase Not Applicable Recruiting 1 7 Months 160 Benazet Louis, MOTTET Nicolas, Dr 2020-05-29
LICCI: Trial of antihypertensive losartan for additional benefit in treating COVID 19 infection. Coronavirus disease 19 infection losartan alone, standard of care alone Angiotensin II AT-1 receptor antagonist, Angiotensin II receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sanjay Gandhi Postgraduate Institute of Medical Sciences India 2020-06-01 CTRI/2020/05/025319, LICCI Phase 3 Clinical Not yet recruiting 1 186 Dr Able Lawrence 2020-06-02
Etiology of Lymphopenia in Covid-19 Infection Coronavirus disease 19 infection, Lymphocytopenia blood sampling alone, bone marrow aspiration cytology alone Cairo University Egypt 2020-06-30 2021-12-31 201920008.2, NCT04404608 Phase Not Applicable Not yet recruiting 1 18 Months 90 Dr Medhat Khafagy 2020-06-05
YONAC: Effect of Yoga & Naturopathy in patients with COVID-19 Coronavirus disease 19 infection Yoga & Naturopathy immune boostinng and stress management protocol alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Government Yoga And Naturopathy Medical College Indian Naturopathy And Yoga Graduates Medical Associatio India 2020-05-22 CTRI/2020/05/025320, YONAC Phase 3 Clinical Recruiting 4 658 Manavalan Narayanaswamy 2020-06-02
Comparison of the ID NOW and Accula Point-of-Care Assays for Detection of COVID-19 Coronavirus disease 19 infection Accula (Mesa Biotech) alone, ID Now (Abbott) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ascension South East Michigan US 2020-05-10 2021-05-09 1599159, NCT04403035 Phase Not Applicable Recruiting 1 12 Months 100 Leonard B Johnson, MD, Leonard B. Johnson, MD, Melphine Harriott, PhD 2020-05-29
The Hope Coalition - 1: Hydroxychloroquine and Lopinavir + Ritonavir to Improve the Health of People With COVID-19 Coronavirus disease 19 infection, Respiratory disease hydroxychloroquine alone, lopinavir + ritonavir alone, hydroxychloroquine plus lopinavir + ritonavir HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cardresearch - Cardiologia Assistencial e de Pesquisa LTDA Cytel Inc Brazil 2020-05-28 2020-11-28 COVID19-AMB-BRASIL, NCT04403100, The Hope Coalition - 1 Phase 3 Clinical Not yet recruiting 4 6 Months 1968 Daniela Silva, MD, PhD, Eduardo Silva, MD, PhD, Gilmar Reis, MD, PhD, Gilmar Reis, MD,PhD, Izabel Silva, SC, Leonardo Savassi, MD, PhD, Rosemary Oliveira, SC 2020-05-29
PH-94B in the Treatment of Adjustment Disorder With Anxiety Adjustment disorder, Anxiety disorder, Coronavirus disease 19 infection PH-94B alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) VistaGen Therapeutics Inc US 2020-11-30 2021-09-30 COVID19_IMPACT, NCT04404192, PH94B-CL-029 Phase 2a Clinical Not yet recruiting 1 10 Months 30 Ann Draine, Matt Turzilli, Michael Liebowitz, MD 2020-05-29
Tablet PINAK given as treatment to COVID positive patients Coronavirus disease 19 infection PINAK alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shree Bharadi Ayurvedic Pharamaceuticals India 2020-05-31 CTRI/2020/05/025326 Phase 2 Clinical Not yet recruiting 1 30 Dr Pandurang Pawar, Shreepad Bhat 2020-06-02
PedCan-COVID: Extraordinary Measures for Egyptian Children With Hemato-Oncological Disorders During COVID-19 Pandemic Coronavirus disease 19 infection, Hematological disease, Hematological neoplasm, Respiratory disease, Solid tumor chest x-ray alone, computed chest tomography alone, reverse transcription polymerase chain reaction test alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Ain Shams University Egypt 2020-01-01 2021-06-01 FMASU P25A/ 2020, NCT04404244, PedCan-COVID Phase Not Applicable Recruiting 1 17 Months 100 Fatma Ebeid, Fatma Soliman E Ebeid 2020-06-02
To study some blood tests which would help predict severity and outcome in children with cancers having the novel corona virus infection Coronavirus disease 19 infection Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) Christian Medical College, Vellore, India India 2020-06-09 CTRI/2020/05/025327 Phase Not Applicable Not yet recruiting 1 60 Deepthi Boddu 2020-06-02
COLORIT: Colchicine Versus Ruxolitinib and Secukinumab In Open, Prospective, Randomized Trial Coronavirus disease 19 infection, Viral pneumonia colchicine alone, ruxolitinib alone, secukinumab alone IL-17 antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) MV Lomonosov Moscow State University Russian Federation 2020-05-08 2020-08-23 COLORIT, MSU080520, NCT04403243 Phase 2 Clinical Recruiting 1 3 Months 70 Julia Begrambekova, Phd, Julia Leonovna Begrambekova, Phd, Yana Orlova, Professor 2020-05-29
TOCIBRAS: Safety and Efficacy of Tocilizumab in Moderate to Severe COVID-19 With Inflammatory Markers Coronavirus disease 19 infection Best supportive care alone, tocilizumab (intravenous), Roche/Chugai alone, tocilizumab (subcutaneous), Roche/Chugai alone IL-6 receptor antagonist, IL-6 receptor modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Beneficencia Portuguesa of Sao Paulo Brazilian Clinical Research Institute, Brazilian Research In Intensive Care Network, Hospital Alemao Oswaldo Cruz, Hospital do Coracao, Instituto de Educação e Pesquisa do Hospital Moinhos de Vento, Sociedade Beneficente Israelita Brasileira Hospital Albert Einsten, Sociedade Beneficiente De Senhoras Hospital Sirio Libanes Brazil 2020-05-08 2020-08-31 NCT04403685, TOCIBRAS, TOCIBRAS Phase 3 Clinical Recruiting 7 3 Months 150 Alexandre Biasi Cavalcanti, MD, Danielle Leao Cordeiro de Farias, MD, Danielle Leão Cordeiro de Farias, MD, Flavia R Machado, Joao Prats, MD, Luciano Azevedo, Phillip Scheinberg, MD, Viviane C Veiga, MD, Viviane Veiga, MD 2020-05-29
The Acai Berry COVID-19 Anti-inflammation Trial Coronavirus disease 19 infection acai palm berry extract (Nature's Way) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The University Health Network University of Toronto Canada 2020-05-31 2021-05-31 CTO3176, NCT04404218 Phase 2 Clinical Not yet recruiting 2 12 Months 480 Ana Andreazza, PhD, Hassan Ellaban, Michael Farkouh, MD, MSc 2020-05-29
TaCOVID: Tannin Specific Natural Extract for COVID-19 Infection Coronavirus disease 19 infection antibiotic therapy alone, antipyretics therapy alone, non-invasive ventilation alone, supplemental oxygen therapy alone, Variable regimens including ARBOX , azithromycin , hydroxychloroquine , lopinavir + ritonavir HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Jose de San Martin Hospital de Clinicas SILVATEAM Argentina 2020-06-01 2020-10-31 HCJSM-20-005, NCT04403646, TaCOVID Phase 2 Clinical Not yet recruiting 1 5 Months 140 Maria M Piskorz, MD, Maria Marta Piskorz, MD 2020-05-28
COVID PLASMA: Study to Assess the Safety and Efficacy of Convalescent Plasma on outcome of COVID-19 Associated Complications Coronavirus disease 19 infection convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Indraprastha Apollo Hospitals India 2020-06-01 COVID PLASMA, CTRI/2020/05/025328, Protocol No. Covid 19, Version no 1.1 Phase 2 Clinical Not yet recruiting 5 100 Dr D Suresh Kumar, Dr Rajesh Chawla, Dr Suneetha Narreddy, Dr Suresh Ramasubban, Dr Tushar Parmar 2020-06-02
CISCO-19: Cardiac Imaging in SARS-CoV-2 (COVID-19) Coronavirus disease 19 infection, Heart injury, Myocarditis, Pulmonary heart disease MRI alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) NHS Greater Glasgow and Clyde University of Glasgow UK 2020-05-22 2021-08-31 CISCO-19, GN20ID164, NCT04403607 Phase Not Applicable Recruiting 3 15 Months 180 Colin Berry, MBChB/PhD, Douglas Grieve, MBChB/PhD, Hannah Bayes, MBChB/PhD, Kenneth Mangion, MBChB/PhD, Kevin Blyth, MBChB/PhD, Lynsey Gillespie, PhD 2020-06-03
Performance Evaluation of RealDetect COVID-19 RT-PCR Kit for the Detection of SARS-CoV-2 Virus Coronavirus disease 19 infection RealDetect COVID-19 RT-PCR kit alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Bangladesh Medical Research Council (BMRC) Bangladesh 2020-05-18 2020-07-24 30005052020, NCT04403672 Phase Not Applicable Recruiting 1 2 Months 120 Rosy Sultana, MBBS, MPhil, Zahid Hassan, MBBS, PhD 2020-06-01
SR4COVID: Protect and prevent onset of COVID like infections in Health Care Workers and High risk person Coronavirus disease 19 infection REIMMUGEN plus SUVED Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Health Solutions, India India 2020-05-30 CTRI/2020/05/025334, SR4COVID Phase 2 Clinical Not yet recruiting 1 30 Shreepad Bhat, Sujata Vaidya 2020-06-01
The Clinical Difference Between the Nonfatal Patients and the Fatal Patients With Severe COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The First Affiliated Hospital of Guangzhou Medical College China 2020-02-01 2020-06-20 NCT04403009, YLS2020(112) Phase Not Applicable Recruiting 2 4 Months 100 jianheng zhang, MD 2020-05-28
PRE-VENT: Study in Hospitalized Patients With Severe COVID-19 With or Without Cancer Coronavirus disease 19 infection pacritinib alone, standard of care alone CSF-1 antagonist, Cytochrome P450 reductase inhibitor, Flt3 tyrosine kinase inhibitor, IRAK-1 protein kinase inhibitor, Jak2 tyrosine kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) CTI BioPharma Corp US 2020-05-22 2021-10-31 NCT04404361, PAC319, PRE-VENT Phase 3 Clinical Recruiting 1 17 Months 358 John Mascarenhas 2020-06-04
A biomarker study to assess the correlation between LIGHT levels and disease severity and mortality in a COVID-19 acute respiratory distress syndrome (ARDS) Coronavirus disease 19 infection, Respiratory distress syndrome Healthy volunteers accepted Cerecor Inc, Myriad Genetics Inc Phase Not Applicable Status not specified 0 77 2020-05-28
EpiCovCreil: Study of SARS-CoV2 Virus (COVID-19) Seroprevalence in the Population of Creil Air Force Base (BA110) Coronavirus disease 19 infection Anti-SARS-CoV2 serology test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Direction Centrale du Service de Sante des Armees France 2020-05-31 2021-02-28 2020-COVID19-22, EpiCovCreil, NCT04404270 Phase Not Applicable Not yet recruiting 1 9 Months 2500 Anaïs GROSSET-JANIN, MD, Sandrine DURON, MD, PhD 2020-05-29
SARS Cov-2 in Conjunctival Secretion Coronavirus disease 19 infection, Viral pneumonia rtPCR alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Università degli Studi dell'Insubria Italy 2020-02-01 2020-05-20 72/2020, NCT04402853 Phase Not Applicable Completed 1 3 Months 100 Simone Donati, Professor 2020-06-02
SARS-CoV-2 Saliva Coronavirus disease 19 infection Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Hospital Sungai Buloh Ministry of Health, Malaysia Malaysia 2020-05-18 2020-08-17 NMRR-20-902-54894 Phase Not Applicable Not yet recruiting 1 3 Months 12 Dr Denisa Khoo Fern Ying, Dr Kalaiarasu Peariasamy 2020-05-29
Rapid antigen detection for SARS-CoV-2 Coronavirus disease 19 infection rapid antigen detection test alone National Institutes of Health Malaysia Ministry of Health, Malaysia Malaysia 2020-06-01 2022-02-28 54859, NMRR-20-944-54859 Phase Not Applicable Status not specified 1 21 Months Dr Norazah binti Ahmad, Ms Jamaayah Bt Mohamed Zahidi @ Ahmad Bakri 2020-05-29
HCW-COVID Coronavirus disease 19 infection HOSPITAL RAJA PEREMPUAN ZAINAB II Malaysia 2020-06-01 2021-06-01 55011, NMRR-20-952-55011 Phase Not Applicable Status not specified 1 12 Months 2000 Dr Diana Foo Hui Ping, Dr LEE HUEY CHUN 2020-06-02
Generation of immune Fab phage display library against a novel coronavirus (2019-nCoV) Coronavirus disease 19 infection Universiti Sains Malaysia Malaysia 2020-02-20 2020-12-31 34314, NMRR-17-3569-34314 Phase Not Applicable Status not specified 1 10 Months Dr Jeyanthi a/p Suppiah, Dr. Mohammad Ridhuan Bin Mohd Ali 2020-05-29
Detailed Organ System Analysis of Asymptomatic COVID19 patients using noninvasive mobile tool Coronavirus disease 19 infection Lyfas Mobile tool alone Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Acculi Labs India 2020-06-05 CTRI/2020/05/025345 Phase Not Applicable Not yet recruiting 1 100 Dr Pooja Sharma, Dr Sushila Kataria, Rishikesh Ranjan 2020-05-29
LSALT Peptide versus Placebo to Prevent ARDS and Other Organ Injuries in Patients Infected With SARS-CoV-2 (COVID-19) Blood clotting disorder, Coronavirus disease 19 infection, Liver injury, Lung inflammation, Myocardial disease, Nephritis, Renal injury, Respiratory distress syndrome Metablok alone, standard of care alone Dehydropeptidase-1 modulator Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Arch Biopartners Inc Canada 2020-07-01 2021-06-30 AB002, NCT04402957 Phase 2 Clinical Not yet recruiting 1 12 Months 60 Daniel A Muruve, MD, Richard Muruve 2020-06-03
Pulmozyme to Improve COVID-19 ARDS Outcomes Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure, Viral pneumonia dornase alfa alone, standard of care alone Deoxyribonuclease I stimulator, Deoxyribonuclease stimulator Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Boston Children's Hospital Brigham & Women's Hospital US 2020-05-25 2021-12-31 NCT04402944, P00035140 Phase 2 Clinical Not yet recruiting 1 19 Months 60 Benjamiin Raby, Robert Fowler 2020-05-29
A Clinical Trial to Assess the Safety and Efficacy of Convalescent Plasma in Severe COVID-19 patients Coronavirus disease 19 infection convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Government of Tamil Nadu India 2020-06-01 CTRI/2020/05/025346, Form CT-06, No. CT/BP/07/2020 Phase 2 Clinical Not yet recruiting 1 90 Dr Latha B, Dr S Anbuselvi Mattuvar Kuzhali, DrJAYANTHI RANGARAJAN 2020-06-03
Resistir: Th1/Th2/Th17/TREG and TLRs Activation/KIR for COVID-19 Prediction of Outcome Coronavirus disease 19 infection RT-PCR alone, flow cytometry alone, plasma sampling alone, polymerase chain reaction alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Asociacion para el Estudio de las Enfermedades Infecciosas Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal Spain 2020-05-22 2020-09-30 EC128/20, NCT04403061, Resistir Phase Not Applicable Recruiting 1 4 Months 80 Alejandro Vallejo, MD, PhD, Ana Moreno, MD, PhD, Carmen Quereda, MD, PhD, Jose L Casado, Md, PhD, Jose M Del Rey, MD, PhD, Pilar Vizcarra, MD 2020-05-29
'Increasing Physical Activity in Canadian Adults Who Have Been Affected by COVID-19 Social Distancing Restrictions: A Feasibility Trial of an Online Intervention' (COVID-19) Coronavirus disease 19 infection Digital Health Online Platform alone, baseline questionnaire alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Victoria Canada 2020-05-20 2020-09-30 05-281983, NCT04400305 Phase Not Applicable Recruiting 1 4 Months 40 Ryan Rhodes, Sandy L Courtnall, Stina Grant 2020-05-29
Prospective, Natural History Study of Smoking, Immune Cell Profiles, Epigenetics and COVID-19 Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) National Institute Of Environmental Health Sciences National Institutes of Health Clinical Center US 2020-06-05 2022-05-31 20-E-0108, 200108, NCT04403386 Phase Not Applicable Recruiting 2 23 Months 200 Nicole Edwards, Stavros Garantziotis, M.D. 2020-06-03
Study to assess safety and efficacy of Inj Sepsivac in patients of COVID-19 Coronavirus disease 19 infection Sepsivac alone, standard therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) RD Gardi Medical College India 2020-05-31 CTRI/2020/05/025350 Phase 2 Clinical Not yet recruiting 1 50 Dr Ashish Pathak 2020-05-29
QTW2020: COVID-19 Brief Advice and Chat-based Support for Smoking Cessation Via 'Quit to Win' Contest 2020 Coronavirus disease 19 infection, Nicotine dependence AWARD advice alone, COSH booklet alone, COVID-19 specific advice alone, COVID-related health warning leaflet alone, Personalized instant messaging alone, referral card alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The University of Hong Kong Hong Kong Council on Smoking and Health Hong Kong 2020-06-13 2022-06-30 NCT04399967, QTW 2020, QTW2020 Phase Not Applicable Not yet recruiting 1 24 Months 842 Man Ping Kelvin Wang, PhD, Xue Weng, PhD 2020-05-29
FAITH: A Phase III study of Favipiravir and Umifenovir in hospitalized patients of moderate COVID-19 in India Coronavirus disease 19 infection standard supportive care alone, favipiravir plus umifenovir RNA polymerase inhibitor Glenmark Pharmaceuticals Ltd India FAITH Phase 3 Clinical Planned 1 158 2020-06-01
A Study of APL-9 in Adults With Mild to Moderate ARDS Due to COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure APL-9 alone, standard of care alone Complement C3 inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Apellis Pharmaceuticals Inc US 2020-05-26 2020-11-30 APL9-COV-201, NCT04402060 Phase 1/Phase 2 Clinical Recruiting 4 6 Months 66 Apellis Clinical Trial Information Line 2020-06-01
CACOLAC: Citrulline Administration in the Hospital Patient in Intensive Care for COVID-19 Acute Respiratory Distress Syndrome Coronavirus disease 19 infection, Lung disease, Respiratory distress syndrome, Viral pneumonia L-citrulline alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rennes University Hospital France 2020-06-15 2021-07-15 2020-A01189-30, 35RC20_9815_CACOLAC, CACOLAC, CPP 1288 HPS1, NCT04404426 Phase Not Applicable Not yet recruiting 5 13 Months 100 Agathe Delbove, MD, Aurélien Frerou, MD, Erwan L'Her, MD, Florian Reizine, MD, Jean-Marc Tadié, MD, Pierre Asfar, MD 2020-05-29
IVERCOVID: Does ivermectin cure and/or prevent COVID-19? Coronavirus disease 19 infection Lagos State University Teaching Hospital Nigeria 2020-04-23 2020-06-23 ISRCTN40302986, IVERCOVID Phase Not Applicable Recruiting 2 2 Months Prof Babalola 2020-05-29
StudentCov: Psychological Impact of the Covid-19 Pandemic on Student Nurses Coronavirus disease 19 infection, Post traumatic stress disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Hospital, Versailles France 2020-05-12 2020-07-31 NCT04402229, P17/04_STUDENTCOV, StudentCov Phase Not Applicable Recruiting 2 2 Months 2000 Guillaume Decormeille, RN, MSc, Gwenaelle Jacq, RN, Jacq Gwenaelle, Stephane Legriel, MD, PhD 2020-05-29
Real-World Antiviral Therapy In COVID-19 Coronavirus disease 19 infection antiviral therapy alone Hospital Universiti Sains Malaysia Malaysia 2020-05-20 2021-08-31 54911, NMRR-20-1006-54911 Phase 4 Clinical Not yet recruiting 4 15 Months Dr Lee Yeong Yeh, SITI NORIZAN BINTI ABDUL RANI 2020-05-29
A trial to assess that almitrine could raise oxygen levels in the blood in COVID-19 patients in order to improve their chances of recovery Coronavirus disease 19 infection almitrine alone University of Oxford LifeArc UK Phase Not Applicable Status not specified 1 Chris Schofield, Dr Matthew Frise, Dr Matthew Rowland, Dr Matthew Wise, Dr Nayia Petousi, Dr Nick Talbot, Dr Stuart McKechnie, Keith Dorrington, Peter Robbins 2020-06-04
A comprehensive evaluation of COVID-19 and diabetes Coronavirus disease 19 infection, Diabetes mellitus Teluk Intan Hospital Malaysia 2020-05-22 55082, NMRR-20-999-55082 Phase Not Applicable Status not specified 1 Dr Dilashini A/P Sundaran Sagaran 2020-06-05
COVID-19 Seroprevalence in RRT patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Malaya Medical Centre Malaysia 2020-06-01 2020-12-31 54927, NMRR-20-997-54927 Phase Not Applicable Not yet recruiting 2 7 Months 650 Dr Rosnawati Yahya, LIM SOO KUN 2020-05-29
Efficacy of AYUSH-64 (a polyherbal formulation) in COVID - 19 Cases Coronavirus disease 19 infection AYUSH-64 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Central Council for Research in Ayurvedic Sciences India 2020-05-31 CTRI/2020/05/025335 Phase 3 Clinical Not yet recruiting 1 40 Dr N R Singh, Dr Vidula Gujjarwar 2020-06-02
Randomized Controlled Trial Of Resveretrol-Copper Or Sodium-Copper-Chlorophyllin Vs Standard Treatment In Mild Covid-19 infection Coronavirus disease 19 infection Resveratrol- Copper alone, antibacterial therapy alone, antibiotic therapy alone, antimicrobial therapy alone, antiviral therapy alone, sodium-copper-chlorophyllin alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tata Memorial Centre India 2020-06-01 CTRI/2020/05/025336 Phase 3 Clinical Not yet recruiting 1 300 Indraneel Mittra, Vikram Gota 2020-06-02
Randomized Controlled Trial Of Resveretrol-Copper OR Sodium-Copper-Chlorophyllin Versus Standard Treatment In Severe Covid-19 Coronavirus disease 19 infection Resveratrol- Copper alone, antibacterial therapy alone, antibiotic therapy alone, antimicrobial therapy alone, antiviral therapy alone, sodium-copper-chlorophyllin alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tata Memorial Centre India 2020-06-01 CTRI/2020/05/025337 Phase 2 Clinical Not yet recruiting 1 200 Indraneel Mittra, Vikram Gota 2020-06-02
Predictive Models for Intensive Care Admission and Death of COVID-19 Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), African Ancestry, European Ancestry Cliniques Saint-Pierre Ottignies Belgium 2020-03-01 2021-01-01 0410508057, NCT04401228 Phase Not Applicable No longer recruiting 1 10 Months 60 Nicolas Parisi 2020-05-29
COLIDE: COVID-19: Laser Interferometry for Rapid Single Coronavirus Detection Coronavirus disease 19 infection laser interferometry test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Somerset NHS Foundation Trust Exeter University, University of Plymouth UK 2020-06-30 2021-12-31 COLIDE, NCT04401644, RBA20203 Phase Not Applicable Not yet recruiting 1 18 Months 250 Flora Darch, Karen Tanner 2020-05-29
Evaluation of Efficacy and Safety of Ayurveda Intervention (Ayush -64) in the management of COVID-19 infection (Asymptomatic &Mild to Moderate symptoms Coronavirus disease 19 infection Ayush 64 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Council for Research in Ayurvedic Sciences India 2020-06-02 CTRI/2020/05/025338 Phase 2/Phase 3 Clinical Not yet recruiting 1 40 Dr BabitaYadav, Dr Manoj Shamkuwar, Dr Shivshankar Rajput 2020-06-02
Prevalence and Severity of Venous Thromboembolism in a General Population During the COVID-19 Pandemic Coronavirus disease 19 infection, Deep vein thrombosis, Lung embolism CT pulmonary angiogram alone, ultrasound alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Linkoeping Sweden 2020-06-01 2020-06-30 NCT04400877, SE2020-02701 Phase Not Applicable Not yet recruiting 1 1 Month 12000 Daniel Wilhelms, Daniel Wilhelms, PhD, Jens Wretborn, MD, Joakim Henricson, PhD, Matthias Jörg, MD, Patrik Benjaminsson Nyberg, PhD 2020-05-29
Treatment and economical problems faced due to non COVID patients admitted in severe acute respiratory illness (SARI) ICU based on SARI criteria Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kasturba Medical College and Hospital India 2020-06-02 COVID_IMPACT, CTRI/2020/05/025339 Phase Not Applicable Not yet recruiting 2 500 Dr Sumalatha A, Dr Sunil R 2020-06-02
Controlled and randomized trial to assess the safety and efficacy of hydroxychloroquine chemoprophylaxis in SARS CoV2 infection in hospital healthcare personnel (Sanitarios sin COVID-19) Coronavirus disease 19 infection, SARS coronavirus infection Hydroxychloroquine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Fundacion Instituto de Investigacion Marques de Valdecilla, IDIVAL Spain 2020-05-15 2020-001704-42, SANsinCOVID Phase 4 Clinical No longer recruiting 1 450 Mar García Sáiz 2020-05-29
Clinical trial of ShatPlus in SARS-CoV-2 Infection Coronavirus disease 19 infection ShatPlus alone, Standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) BVG Life Sciences Ltd India 2020-06-01 CTRI/2020/05/025340, PROTOCOL NO- MHC/CT/20-21/001 Phase 1/Phase 2 Clinical Not yet recruiting 1 60 Dr Patsute Sudhir Dadaram, Dr Pawan Kumar Singh 2020-06-02
Study on Safety and Efficacy of Favipiravir (Favipira) for COVID-19 Patient in Selected Hospitals of Bangladesh Coronavirus disease 19 infection favipiravir alone, standard treatment alone RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Bangladesh Medical Research Council (BMRC) Bangladesh 2020-05-31 2020-07-31 29318042020, NCT04402203 Phase 2/Phase 3 Clinical Recruiting 1 2 Months 50 Ahmedul Kabir, MBBS, FCPS FACP, FRCP, Ahmedul Kabir, MBBS, FCPS, FACP, FRCP, Md. Billal Alam, MBBS, FCPS MD, MACP, FACP 2020-05-29
CALYPSO: COVID-19 Associated Lymphopenia Pathogenesis Study in Blood Coronavirus disease 19 infection, Lymphocytopenia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Allergy and Infectious Diseases National Institutes of Health Clinical Center US 2020-05-22 2022-06-30 20-I-0111, 200111, CALYPSO, NCT04401436 Phase Not Applicable Recruiting 2 25 Months 165 Irini Sereti, M.D., Princy Kumar, M.D. 2020-05-29
A study to know the effect of Ayurvedic Kwath(Kiratiktadi Kwath) and Ashwagandha Churna along with yoga exercises in the treatment of COVID-19 Positive patients Coronavirus disease 19 infection Variable regimens including Ashwagandha churna , Kiratiktadi Kwath Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) GS Ayurveda Medical College & Hospital India 2020-06-02 CTRI/2020/05/025341 Phase Not Applicable Not yet recruiting 1 30 Ankur Singhal 2020-06-02
Efficacy of vitamin D treatment in patients diagnosed with pneumonia who require hospital admission and have vitamin D deficiency and a positive diagnosis for SARS-Cov-2 (COVID-19) Coronavirus disease 19 infection, Viral pneumonia, Vitamin D deficiency Hidroferol alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Investigation Institute Bioaraba Spain 2020-05-25 2020-001960-28, RCTVITD/SARS-CoV-19 Phase 4 Clinical Recruiting 1 108 Inés Pérez Francisco 2020-05-29
Nigella Sativa in COVID-19 Coronavirus disease 19 infection, Upper respiratory tract infection Nigella sativa seed oil alone, standard care protocol alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) King Abdulaziz University Saudi Arabia 2020-05-21 2020-12-31 266-20, NCT04401202 Phase 2 Clinical Recruiting 1 7 Months 200 Abdulrahman Koshak, Dr, Dr Abdulrahman E. Koshak 2020-05-29
SARSCoV2CZPrev: COVID-19: Herd Immunity Study in the Czech Republic Coronavirus disease 19 infection Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institute of health information and statistics of the Czech Republic Central Military Hospital, Prague, Charles University, Czech Academy of Sciences, Czech Statistical Office, Faculty Hospital Olomouc, General University Hospital, Prague, Institut Klinické a Experimentální Medicin, Krajská zdravotní, a.s., Ústí nad Labem Region Hospitals, MasaryKuv Onkologicky Ustav, Masaryk University, Ministry of Health, Czech Republic, Palacky University, University Hospital Brno, University of Defence in Brno, University of Ostrava, Univerzita Jana Evangelisty Purkyne Prirodovedecka Fakulta Czech Republic 2020-04-23 2020-05-01 NCT04401085, SARSCoV2CZPrev, UZIS 2020/1 Phase Not Applicable Completed 1 27000 Aleksi Šedo, Prof., Dalibor Valík, Prof., David Feltl, Prof., Jarmila Rážová, M.D., Ph.D., Jaroslav Štěrba, Prof., Ladislav Dušek, Prof., Marián Hajdúch, Assoc. Prof., Martin Repko, Prof., Rastislav Maďar, Assoc. Prof., Roman Chlíbek, Prof., Roman Prymula, Prof., Vladimír Černý, Prof., Věra Adámková, Prof., Zdeněk Havel, Assoc. Prof. 2020-06-02
SARTRE: Multicenter, randomized, open-label study to evaluate the efficacy and safety of SOC + sarilumab versus standard of care for the early treatment of COVID-19-pneumonia in hospitalized patients Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia sarilumab alone, standard of care alone IL-6 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidad Autonoma de Madrid SANOFI-AVENTIS, S.A Spain 2020-05-25 2020-002037-15, SARTRE, SARTRE Phase 2 Clinical Recruiting 1 200 Belen Ruiz Antorán 2020-06-05
ACTIVATE II: Bacillus Calmette-guerin Vaccination to Prevent COVID-19 Coronavirus disease 19 infection BCG vaccine (Serum Institute of India Pvt. Ltd) alone Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hellenic Institute for the Study of Sepsis Radboud University Greece 2020-05-26 2021-05-25 2020-002448-21, ACTIVATE II, Activate II, NCT04414267 Phase 4 Clinical Recruiting 1 12 Months 900 Antigoni Kotsaki, MD, PhD, Antonios Papadopoulos, MD, PhD, Charalambos Gogos, MD, PhD, Charalambos Milionis, MD, PhD, Christos Chasikidis, MD, Christos Koutras, MD, Evangelos Giamarellos-Bourboulis, MD, PhD, Garyfallia Poulakou, MD, PhD, Georgios Adamis, MD, Helen Sambatakou, Karolina Akinosoglou, MD, PhD, Konstantinos Dolianitis, MD, Konstantinos Katsaros, MD, Periklis Panagopoulos, MD, PhD, President of the Board, Simeon Metallidis, MD, PhD 2020-06-05
Using GM-CSF as a Host Directed Therapeutic Against COVID-19 Coronavirus disease 19 infection, Hypoxia, Respiratory failure, Viral pneumonia sargramostim alone, standard of care alone CSF-1 agonist, GM-CSF receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Singapore General Hospital Pte Ltd Singapore 2020-06-30 2022-06-30 NCT04400929, SH-LEUK-01 Phase 2 Clinical Recruiting 1 24 Months 30 Jenny Low, MBBS 2020-06-05
Colchicine for the Treatment of Hyperinflammation Associated with Pneumonia due to COVID-19 Coronavirus disease 19 infection, Inflammatory disease, Viral pneumonia colchicine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Spanish Society of Cardiology Spain 2020-05-25 2020-001841-38, Col-VID Phase 3 Clinical Recruiting 1 240 Alberto Cecconi 2020-05-29
Impact of remote audio-visual surveillance of doffing process during COVID 19 pandemic on the safety of health care workers Coronavirus disease 19 infection remote audio-visual surveillance alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Postgraduate Institute of Medical Education and Research India 2020-05-30 CTRI/2020/05/025274 Phase Not Applicable Not yet recruiting 1 100 AJAY SINGH 2020-05-29
Role of Chyawanprash in the prevention of COVID-19 in health care workers Coronavirus disease 19 infection Chyawanprash alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Central Council for Research in Ayurveda and Siddha India 2020-05-30 CTRI/2020/05/025275 Phase 3 Clinical Not yet recruiting 1 200 Dr Arun Gupta, Prof Dr Vidula Gujjarwar 2020-05-29
Effect of Ayurvedic intervention in COVID-19 positive cases Coronavirus disease 19 infection Variable regimens including Amalaki Churna , Golden Milk , Nagaradi kwath , Sanshamani Vati Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Chaudhary Brahm Prakash Ayurved Charak Sansthan India 2020-05-29 CTRI/2020/05/025276 Phase 3 Clinical Not yet recruiting 1 50 Dr Arun Gupta, ProfDr Vidula Gujjarwar 2020-05-29
Attitude of Egyptian Population Toward COVID-19 in Ramadan Coronavirus disease 19 infection Healthy volunteers accepted Damanhour University Egypt 2020-04-24 2020-10-31 COVID 19 IN RAMADAN, NCT04401072 Phase Not Applicable Recruiting 1 6 Months 500 Amira Kassem, PHD, Amira kassem, PHD, Noha El bassiouny, PHD, Noha el bassiouny, PHD 2020-05-28
DECORE: Increased Risk of SARS-CoronaVirus-2 (SARS-CoV-2) Infection Associated With Endoscopy Coronavirus disease 19 infection abdominal ultrasound alone, gastrointestinal endoscopy alone, telephonic medical visit alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Hospital del Río Hortega Spain 2020-05-11 2020-06-30 003, DECORE, NCT04401033 Phase Not Applicable Recruiting 1 1 Month 450 Manuel Pérez-Miranda Castillo, MD PhD, Marina De Benito, MD, Marina de Benito Sanz, Marina de Benito Sanz, MD 2020-05-28
SU-REM-COVID: Study results of Ayurvedic treatment on COVID patients using proprietary herbal formulation SUVED and whole colostrum REIMMUGEN Coronavirus disease 19 infection REIMMUGEN plus SUVED Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Health Solutions, India India 2020-05-30 CTRI/2020/05/025343, SU-REM-COVID Phase 2/Phase 3 Clinical Not yet recruiting 1 30 Shreepad Bhat, Sujata Vaidya 2020-06-02
SARS-CoV-2 in Malaysia Coronavirus disease 19 infection Institute For Medical Research (Inc In Malaysia), University of Malaya Malaysia 2020-03-17 54197, NMRR-20-536-54197 Phase Not Applicable Not yet recruiting 2 3000 Dr Norazah binti Ahmad, Professor Dr Jamal I-Ching Sam 2020-05-28
Effects of Temperature and Humidity on the Transmission of SARS-CoV-2: A Systematic Review Protocol Coronavirus disease 19 infection National Institutes of Health Malaysia, Universiti Kebangsaan Malaysia Malaysia 2020-04-17 2020-04-24 NMRR-20-725-54662 Phase Not Applicable Status not specified 2 Dr CHANDRIKA JEEVANANTHAN, Dr Nor Asiah Muhamad, Dr. Rimah Melati binti Ab. Ghani 2020-06-02
Binding Potentials of Probiotics to SARS-COV-2 Spike Proteins Coronavirus disease 19 infection Universiti Sains Malaysia Malaysia 2020-04-20 2021-04-19 54688, NMRR-20-758-54688 Phase Not Applicable Not yet recruiting 5 12 Months 100 Prof Dr Liong Min Tze 2020-06-02
A clinical trial of DNA vaccine for the potential treatment of novel coronavirus (Coronavirus disease 19 infection) Coronavirus disease 19 infection DNA vaccine alone AnGes MG Inc 2020-07-31 Phase Not Applicable Planned 0 2020-06-01
A multicenter registry analysis on the use of hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19 Coronavirus disease 19 infection chloroquine alone, hydroxychloroquine alone, Variable regimens including chloroquine , hydroxychloroquine , macrolide Brigham & Women's Hospital US Phase Not Applicable Status not specified 1 96032 2020-06-03
A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of EB-05 + SOC versus Placebo + SOC in Adult Hospitalized Patients With Moderate to Severe COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia EB-05 alone, standard of care alone TLR-4 antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Edesa Biotech Inc JSS Medical Research Inc 2020-08-31 2021-04-30 EB05-01-2020, NCT04401475 Phase 2/Phase 3 Clinical Not yet recruiting 0 8 Months 865 Blair Gordon, PhD 2020-06-03
BAT IT: Anti-SARS Cov-2 T Cell Infusions for COVID-19 Coronavirus disease 19 infection anti-SARS Cov-2 T Cell alone, Tylenol plus cetirizine Histamine H1 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Baylor College of Medicine AlloVir, Center for Cell and Gene Therapy, Houston Methodist US 2020-07-30 2021-08-15 BAT IT, H-47739 BAT IT, NCT04401410 Phase 1 Clinical Not yet recruiting 1 12 Months 20 Premal Lulla, Premal Lulla, MD 2020-05-27
CO-Qo-ICU: One-year Outcomes in Survivors of the Severe COVID-19 Pneumonia Coronavirus disease 19 infection, Hypoxia, Respiratory distress syndrome, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire De Nice France 2020-06-16 2021-06-15 20REAMEDCOVID04, CO-Qo-ICU, NCT04401111 Phase Not Applicable Not yet recruiting 1 12 Months 150 Clément SACCHERI, Jean DELLAMONICA, Jean DELLAMONICA, MD, PhD 2020-05-27
LOVIT-COVID: Lessening Organ Dysfunction With Vitamin C - COVID-19 Coronavirus disease 19 infection vitamin C alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universite de Sherbrooke Lotte & John Hecht Memorial Foundation Canada 2020-06-30 2022-01-31 LOVIT-COVID, MP-31-2021-3741, NCT04401150 Phase 3 Clinical Not yet recruiting 1 19 Months 800 François Lamontagne, MD, FRCPC, MSc, Julie Menard, PhD, Marie-Helene Masse, Neill K Adhikari, MDCM, FRCPC, MSc 2020-05-28
COVID-Recovery: Recovery of Patients From COVID-19 After Critical Illness Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Australian and New Zealand Intensive Care Research Centre The Alfred (AU) Australia 2020-05-31 2022-04-30 COVID-RECOVERY V1.0 01MAY2020, COVID-Recovery, NCT04401254 Phase Not Applicable Not yet recruiting 7 23 Months 300 Carol Hodgson, PhD, Natalie Linke, RN 2020-05-27
Cardiac Manifestation of Covid-19 Patients in Children Coronavirus disease 19 infection, Kawasaki disease echocardiography alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Universiti Putra Malaysia Malaysia 2020-05-22 2020-05-30 55099, NMRR-20-1018-55099 Phase Not Applicable Not yet recruiting 1 7 dr putri bt yubbu 2020-05-27
Treatment of Lung Injury From COVID-19 Infection With Intravenous Sodium Nitrite Coronavirus disease 19 infection, Lung injury, Respiratory failure sodium nitrite (intravenous, sickle cell disease/myocardial infarction/cerebral vasospasm), Hope Pharmaceuticals alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hope Pharmaceuticals Inc 2020-06-30 2020-12-31 NCT04401527, SN02-01 Phase 2 Clinical Not yet recruiting 0 6 Months 200 Hope Pharmaceuticals Medical Director 2020-05-28
NGS SARS-CoV-2 Coronavirus disease 19 infection National Institutes of Health Malaysia Malaysia 2020-05-18 2021-12-31 54816, NMRR-20-884-54816 Phase Not Applicable Status not specified 1 19 Months Dr Jeyanthi a/p Suppiah 2020-05-27
In vitro COVID-19 Anti-Viral Screening of Herbal Formulations Coronavirus disease 19 infection herbal formulation therapy alone National Institutes of Health Malaysia Malaysia 2020-05-18 2020-12-31 54715, NMRR-20-874-54715 Phase Not Applicable Status not specified 1 7 Months Dr Mohd Ridzuan Bin Mohd Abd Razak 2020-05-27
Characteristics of Neonatal Covid-19 in Turkey Coronavirus disease 19 infection Healthy volunteers accepted, Newborn Infants (up to 5 months) Recep Tayyip Erdogan University Training and Research Hospital Turkish Neonatal Society Turkey 2020-05-01 2020-10-30 NCT04401540, NICU-COVID-TR Phase Not Applicable Recruiting 1 5 Months 90 Mehmet K Kanburoglu, M.D., Mehmet Kenan Kanburoglu, Mehmet Y Oncel, M.D. 2020-05-28
The Efficacy Comparing Daily and After-each-case Room Disinfection Coronavirus disease 19 infection after-each-case room disinfection alone, daily room disinfection alone The First Affiliated Hospital of Zhejiang Chinese Medical University China 2020-05-25 2020-06-10 DACD-HUY-2005, NCT04399005 Phase Not Applicable Recruiting 1 240 Bin Lu, Bin Lu, M.D., Bo Jin, Bachelor, Liang Huang, Liang Huang, Bachelor, Yue Hu, Yue Hu, M.D. 2020-05-28
SARS-CoV-2, Nasopharygeal swab, Saliva Coronavirus disease 19 infection RT-PCR alone Institute For Medical Research (Inc In Malaysia) Malaysia 2020-05-05 2020-06-30 54884, NMRR-20-860-54884 Phase Not Applicable Status not specified 1 1 Month Dr Mohan Rao Nageswara Rao 2020-05-27
Cardiopulmonary Inflammation and Multi-System Imaging During the Clinical Course of COVID-19 Infection in Asymptomatic and Symptomatic Persons Coronavirus disease 19 infection, Inflammatory disease, Pulmonary heart disease CT scans alone, MRI scans alone, biological sampling alone, bronchoscopy alone, ultrasound alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institutes of Health Clinical Center US 2020-05-21 2024-05-01 20-CC-0113, 200113, NCT04401449 Phase Not Applicable Recruiting 1 47 Months 92 Anthony F Suffredini, M.D. 2020-05-27
A phase II, randomized, placebo-controlled study to evaluate the safety and efficacy of KT-PC-301 for the treatment of acute respiratory distress syndrome symptoms in patients with moderate to severe COVID-19 infection Coronavirus disease 19 infection, Respiratory distress syndrome KT-PC-301 alone Koligo Therapeutics Inc US Phase 2 Clinical Planned 1 75 Mohamed Saad 2020-05-27
ICUCOVID-MY Coronavirus disease 19 infection University Malaya Medical Centre Malaysia 2020-05-31 2020-09-30 54772, NMRR-20-1037-54772 Phase Not Applicable Recruiting 1 4 Months ABDUL JABBAR BIN ISMAIL, Dr Nor Azim bin Mohd Yunos 2020-06-02
OVID: Enoxaparin for Primary Thromboprophylaxis in Ambulatory Patients With COVID-19 Blood clotting disorder, Coronavirus disease 19 infection enoxaparin sodium alone Low molecular weight heparin Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Zurich Centre Hospitalier Universitaire Vaudois, Clinica Luganese Moncucco, Hopitaux Universitaires De Geneve, Oncology Institute of Southern Switzerland, University Hospital Basel, University Hospital Inselspital, Berne Switzerland 2020-06-01 2021-04-14 NCT04400799, OVID, OVID TRIAL Phase 3 Clinical Not yet recruiting 1 10 Months 1000 Nils Kucher, Prof., Rebecca Spescha, Dr. sc. nat. 2020-05-27
A clinical trial of inactivated vaccine (COVID-19), KM Biologics for the potential treatment of COVID-19 infection Coronavirus disease 19 infection inactivated vaccine (COVID-19), KM Biologics alone KM Biologics Co Ltd Phase Not Applicable Planned 0 2020-05-29
Changing Of Egyptian Population Behavior Towards COVID-19 Outbreak Coronavirus disease 19 infection online survey alone Healthy volunteers accepted Damanhour University Egypt 2020-05-02 2021-04-01 COVID 19, NCT04401098 Phase Not Applicable Recruiting 1 11 Months 700 Amira Kassem, PHD, Amira kassem, PHD, Noha El Bassiouny, PHD, Noha El bassiouny, PHD 2020-05-27
HEP-COVID: Full Dose Heparin Versus Prophylactic Or Intermediate Dose Heparin in High Risk COVID-19 Patients Coronavirus disease 19 infection enoxaparin sodium alone Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Northwell Health Inc US 2020-04-26 2021-04-26 20-0340, HEP-COVID, NCT04401293 Phase 3 Clinical Recruiting 6 12 Months 308 Aaron Harrison, MD, Adrian Popp, MD, Alex C Spyropoulos, MD, Andrea Mignatti, MD, Barbara Shannon, RN, Christina Brennan, MD, Cynthia Price, NP, Damian Inlall, CCRC, Dana Kuziw, RN, Eugenia Gianos, MD, George Surguladze, MD, Gulru Sharifova, MD, Jane Hubert, RN, Janice Wang, MD, Jeremy Jacobson, MD, John Flynt, MD, Kevin Molina, Lisa Lumley, RN, Luis Gruberg, MD, Mangala Narasimhan, MD, Marc Cohen, MD, Mark Goldin, MD, Melissa Panzo, RN, Michael Krzyzak, MD, Nazish Ilyas, MD, Negin Hajizadeh, MD, Paul Maccaro, MD, Phyllis Suen, MD, Puneet Gandotra, MD, Richard Dima, MD, Sean Taylor, Wassim Diab, MD 2020-05-28
COVID-TRAUMA: Covid-19 and Reorganisation of Cancer Patient Care: Self-evaluation of Potential Post Traumatic Stress Disorder Coronavirus disease 19 infection, Post traumatic stress disorder Survey alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institut Paoli-Calmettes IPC France 2020-05-30 2020-11-30 COVID-TRAUMA, COVID-TRAUMA-IPC 2020-026, NCT04401046 Phase Not Applicable Not yet recruiting 1 6 Months 4000 Dominique Genre, MD, Gwenaelle GRAVIS, MD, Jihane PAKRADOUNI, PharmD, PhD 2020-06-03
Distance Learning for Dental Student During COVID-19 Pandemic Coronavirus disease 19 infection pediatric dentistry online course alone Cairo University Egypt 2020-05-01 2020-05-10 DISTANCE LEARNING ENVIRONMENT, NCT04401371 Phase Not Applicable Completed 1 418 Maha Moussa, Yasmin Mohamed Yousry 2020-05-27
Status of Management of Surgery in Beijing During COVID-19 Coronavirus disease 19 infection, Gastrointestinal disease surgery alone Beijing Friendship Hospital Beijing Chao-Yang Hospital, Beijing Hospital, China-Japan Friendship Hospital, Chinese PLA General Hospital, Peking Union Medical College Hospital, Peking University Cancer Hospital, Peking University First Hospital, Peking University Shougang Hospital, Peking University Third Hospital, People's Hospital Peking University, Xuanwu Hospital Of Capital Medical University China 2020-05-25 2020-06-07 BFH-SURGERYCOVID, NCT04401124 Phase Not Applicable Not yet recruiting 1 500 Kai Pang, M.D., Zhongtao Zhang, M.D. 2020-05-29
MONACOVID: How Routine Biomarkers and Blood Leucocytes Count Can Assist Diagnosis of COVID-19 in Emergency Department Coronavirus disease 19 infection, Viral pneumonia CT-scan alone, naso-pharyngeal swab sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Princesse Grace Monaco 2020-02-01 2020-05-15 20-06, MONACOVID, NCT04401241 Phase Not Applicable Completed 1 3 Months 257 2020-06-02
ACTT-II: Adaptive COVID-19 Treatment Trial 2 Coronavirus disease 19 infection baricitinib plus remdesivir COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, Jak1 tyrosine kinase inhibitor, Jak2 tyrosine kinase inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Allergy and Infectious Diseases South Korea, Japan, Singapore, US, Mexico 2020-05-08 2023-08-01 20-0006 ACTT-II, ACTT-II, NCT04401579 Phase 3 Clinical Recruiting 52 38 Months 1032 20-0006 Central Contact 2020-06-05
Randomized, Proof-of-Concept Trial to Evaluate the Safety and Explore the Effectiveness of Resveratrol for COVID-19 Coronavirus disease 19 infection Vitamin D3 plus resveratrol Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mount Carmel Health System US 2020-06-30 2020-11-30 MCCREARY2020, NCT04400890 Phase 2 Clinical Not yet recruiting 1 5 Months 200 Marvin R McCreary 2020-05-28
Acute impairment of renal function in COVID-19: study on incidence, risk factors and mortality Coronavirus disease 19 infection, Renal failure Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Unidade de Pesquisa Clínica - Hospital das Clínicas da Faculdade de Medicina de Botucatu Brazil 2020-05-01 30451520.6.0000.5411, CEP: 4.003.880, RBR-62y3h7, U1111-1251-0281 Phase Not Applicable Recruiting 1 1000 Welder Zamoner 2020-05-28
An ongoing study looking at ID NOW's performance compared to two lab-based reference methods in nursing home and hospitalized settings Coronavirus disease 19 infection ID NOW COVID-19 Rapid Test alone Abbott Laboratories US Phase Not Applicable Recruiting 5 2020-06-03
Everett Clinic study: A clinical study to evaluate the efficacy of ID NOW COVID-19 Rapid Test Coronavirus disease 19 infection ID NOW COVID-19 Rapid Test alone Abbott Laboratories Everett Clinic study Phase Not Applicable Status not specified 0 955 2020-05-29
Urgent care clinic study: A multisite clinical study to evaluate the efficacy of ID NOW COVID-19 Rapid Test Coronavirus disease 19 infection ID NOW COVID-19 Rapid Test alone Abbott Laboratories Urgent care clinic study Phase Not Applicable Status not specified 0 256 2020-05-29
Long-term Pulmonary Outcomes After Infection With Sars-CoV-2 Coronavirus disease 19 infection Lung imaging alone, Pulmonary function test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Aarhus University Denmark 2020-05-31 2022-12-31 33510, NCT04401163 Phase Not Applicable Not yet recruiting 1 31 Months 180 Elisabeth Bendstrup, MD, PhD, Søren S Haugen, MD 2020-05-28
PREVICHARM: Prevention of COVID-19 Infection in Nursing Homes by Chemoprophylaxis With Hydroxychloroquine Coronavirus disease 19 infection hydroxychloroquine (Dolquine) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundacion Publica Andaluza para la Investigacion de Malaga en Biomedicina y Salud, University of Malaga Instituto de Investigacion Biomedica de Malaga, Instituto de Salud Carlos III Spain 2020-05-15 2021-04-01 2020-002287-31, COV20/00565, NCT04400019, PREVICHARM, PREVICHARM Phase 2/Phase 3 Clinical Not yet recruiting 3 10 Months 1930 Gloria Luque, José M Morales-Asencio, PhD, José M Morales-Asencio, Professor, Juan C Morilla-Herrera, PhD, Ricardo Gómez-Huelgas, PhD 2020-05-29
TXA COVID-19 Clinical Trial Coronavirus disease 19 infection, Multiple organ failure, Renal injury TXA-127 alone Angiotensin II receptor modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Columbia University US 2020-06-30 2021-12-31 AAAT0535, NCT04401423 Phase 2 Clinical Not yet recruiting 1 18 Months 100 Jeanine D'Armiento, Jeanine D'Armiento, MD, PhD, Laura Fonseca 2020-05-29
Mavrilimumab to Reduce Progression of Acute Respiratory Failure in COVID-19 Pneumonia and Systemic Hyper-inflammation Coronavirus disease 19 infection, Hypoxia, Inflammatory disease, Respiratory failure, Viral pneumonia mavrilimumab alone C-reactive protein inhibitor, Chemokine CC22 ligand inhibitor, GM-CSF receptor antagonist, Hemoglobin scavenger receptor antagonist, Metalloprotease-1 inhibitor, Metalloprotease-3 inhibitor, Small inducible cytokine A17 ligand inhibitor, VEGF gene inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cleveland Clinic Foundation Kiniksa Pharmaceuticals Ltd US 2020-05-20 2021-05-31 IND 149324, IRB 20-523, NCT04399980 Phase 2 Clinical Recruiting 2 12 Months 60 Alice Goyanes, M. D., Calvin Sheng, M. D., Debases Sahoo, M.D., Narendrakumar Alappan, M. D., Ossama K Abou Hassan, M. D., Paul C Cremer, M. D., Prabalini Rajendram, M. D., Ravi Sunderkrishnan, M. D., Robier Aguillon-Prada, M. D., Shiddharth P Dugar, M. D., Tom Wang, M. D., Venu Menon, M. D., Yuki Kuramochi, BSN, RN 2020-05-28
Attitude and Perception Towards COVID-19 Pandemic Coronavirus disease 19 infection Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Zagazig University Egypt 2020-05-19 2020-08-31 NCT04400812, ZU#IRB#6138-17-5-2020 Phase Not Applicable Recruiting 1 3 Months 5000 Waheed Shouman 2020-05-29
Octagam 10% Therapy In COVID-19 Patients With Severe Disease Progression Coronavirus disease 19 infection Octagam 10% alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Octapharma AG, Octapharma USA US 2020-06-01 2020-09-30 2020-002482-34, GAM10-10, NCT04400058 Phase 3 Clinical Not yet recruiting 1 4 Months 54 George Sakoulas, Mikaela Raymond 2020-06-05
Mechanisms of Multi-organ Failure in COVID-19 Coronavirus disease 19 infection, Multiple organ failure Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Imperial College London UK 2020-05-18 2021-11-17 283783, NCT04399603 Phase Not Applicable Not yet recruiting 1 18 Months 120 2020-05-29
Niclosamide for Mild to Moderate COVID-19 Coronavirus disease 19 infection niclosamide alone, standard of care alone, telehealth monitoring alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tufts Medical Center US 2020-06-01 2020-11-30 NCT04399356, STUDY00000605 Phase 2 Clinical Not yet recruiting 1 6 Months 100 Dorothy Dulko, PhD, Harry P Selker, MD 2020-05-28
A retrospective, observational study to explore the clinical characteristics and prognosis of the new coronavirus 2019-nCoV patients combined with cardiovascular disease Cardiovascular disease, Coronavirus disease 19 infection angiotensin receptor blockers (ARBs) alone, angiotensin-converting enzyme inhibitors (ACEIs) alone Union Hospital Tongji Medical School Huazhong University Of Science & Technology China Phase Not Applicable Status not specified 1 112 2020-05-27
Flow Controlled Ventilation in ARDS Associated With COVID-19 Adult respiratory distress syndrome, Coronavirus disease 19 infection Evone-ventilator alone, flow controlled ventilation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hamad Medical Corp Qatar 2020-05-31 2020-08-31 MRC-05-018, NCT04399317 Phase Not Applicable Not yet recruiting 1 3 Months 20 Marcus Lance, MD, PhD, Nabil Shallik, MD 2020-05-29
Ivermectin-Azithromycin-Cholecalciferol (IvAzCol) Combination Therapy for COVID-19 (IvAzCol) Coronavirus disease 19 infection, Respiratory disease Variable regimens including azithromycin , cholecalciferol , ivermectin Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto De Seguridad Y Servicios Sociales De Los Trabajadores Del Estado Mexico 2020-03-15 2020-06-10 IVAZCOL, NCT04399746 Phase 2 Clinical Recruiting 1 2 Months 30 Guadalupe Espitia Hernandez, MD, PhD, Guadalupe Espitia, MD, PhD 2020-05-28
Effect of Lactobacillus on the Microbiome of Household Contacts Exposed to COVID-19 Coronavirus disease 19 infection Lactobaciltus rhamnosus GG alone Healthy volunteers accepted, Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Duke University US 2020-05-25 2022-05-25 NCT04399252, PRO00105674 Phase Not Applicable Not yet recruiting 1 24 Months 1000 Anthony Sung, MD, Lauren Bohannon 2020-05-28
Acceptance of Telemedicine During the COVID-19 Pandemic Coronavirus disease 19 infection telemedicine consultation alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Foundation for Health Research and Biomedical Valencia Philippines 2020-06-01 2020-10-31 NCT04400448, TELECOVID Phase Not Applicable Not yet recruiting 1 5 Months 200 Luis Sánchez Guillen 2020-05-29
Evaluation effect of Dinvl for Covid19 infection Coronavirus disease 19 infection, Viral pneumonia dinvl, Health Medicine Chemistry Company alone, usual treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Baqiyatallah Hospital Iran 2020-06-03 IR.BMSU.REC.1399.154, IRCT20200509047373N1 Phase 2/Phase 3 Clinical Recruiting 1 60 Ahmad Hosseinpour, Mohsen Saberi 2020-06-03
Evaluation efficacy of 'curcumin and resveratrol' capsule in controlling symptoms in patients with COVID-19 Coronavirus disease 19 infection curcumin + resveratrol alone, routine treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bagheiat-allah University of Medical Sciences Iran 2020-05-16 IR.BMSU.REC.1399.129, IRCT20080901001165N56 Phase 3 Clinical Recruiting 1 60 Gholamhosein Alishiri, Morteza Izadi, Parisa Kianpour, Rouhollah Ahmadiyan, Yunes Panahi 2020-05-29
Cyclosporin for the Prevention and Treatment of COVID-19 Disease Coronavirus disease 19 infection, Respiratory failure cyclosporin alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shaheed Beheshti Medical University Iran 2020-03-20 IR.SBMU.NRITLD.REC.1399.058, IRCT20150107020592N22 Phase 3 Clinical Recruiting 1 60 Dr Seyyed Mohamadreza Hashemian, Seyed Mohammad Reza Hashemian 2020-06-02
Low dose whole lung irradiation for treatment of COVID-19 pneumonia Coronavirus disease 19 infection, Lung disease, Respiratory distress syndrome, Viral pneumonia low dose whole lung irradiation (100 Rads) alone Male, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tehran University of Medical Sciences Iran 2020-05-27 IR.TUMS.VCR.REC.1399.362, IRCT20170211032494N3 Phase 2 Clinical No longer recruiting 1 10 Dr. Mohammad Ali Sahraian, Nima Mousavi Darzikolaee 2020-06-04
Polio Vaccine and COVID-19 Coronavirus disease 19 infection oral polio vaccine (Razi Institute) alone Petroleum Industry Health Organization Iran 2020-06-13 IR.SUMS.REC.1399.183, IRCT20140428017469N1 Phase 3 Clinical Not yet recruiting 1 130000 Farrokh Habibzadeh, Habibollah Sami 2020-05-28
A Randomized Study to Assess the Effect of Genedrive 96 SARS-CoV-2 Kit in patients With COVID-19 Coronavirus disease 19 infection Genedrive 96 SARS-CoV-2 Kit alone Genedrive plc Phase Not Applicable Status not specified 0 180 2020-05-26
EMPOWER: BAME versus COVID Coronavirus disease 19 infection Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry, African Ancestry, Japanese Ancestry Future Genetics Limited UK 2020-07-01 2021-10-01 EMPOWER, EMPOWER-BAME VS COVID, NCT04399733 Phase Not Applicable Not yet recruiting 1 15 Months 12800 Dr Mohammed Kamran, Kash Arfan 2020-05-28
Hydroxychloroquine of pharmacokinetics in healthcare workers Coronavirus disease 19 infection Hydroxychloroquine sulphate alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Indian Council of Medical Research India 2020-05-25 83341, CTRI/2020/05/025242 Phase 1 Clinical Not yet recruiting 1 400 Dr Nithya Gogtay 2020-05-28
A study on salivary samples and nasopharyngeal samples in diagnosis of COVID-19 Disease Patients Coronavirus disease 19 infection salivary and nasopharyngeal sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Medanta The Medicity India 2020-05-19 CTRI/2020/05/025243 Phase Not Applicable Not yet recruiting 1 40 Dr Sushila Kataria, Dr Vikas Deswal, Kuldeep K Chauhan 2020-05-28
Ashwagandha for prevention against SARS-CoV-2 Infection: A Randomized, Hydroxychloroquine Controlled drug trial in high risk Health Care Providers Coronavirus disease 19 infection Ashwagandha (Withania somnifera) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Council of Scientific and Industrial Research (India), Ministry of Ayush India 2020-05-28 CTRI/2020/05/025332 Phase 2 Clinical Not yet recruiting 1 400 DR ARVIND CHOPRA 2020-06-02
hCT-MSCs for COVID-19 ARDS Coronavirus disease 19 infection, Respiratory distress syndrome allogenic human cord tissue derived mesenchymal stromal cells (iv, ARDS/COVID-19), Duke University alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Duke University The Marcus Foundation Inc US 2020-06-01 2021-07-31 NCT04399889, PRO00105410 Phase 1/Phase 2 Clinical Not yet recruiting 1 14 Months 30 Bryan Frank, MD, Jennifer Baker, RN, Joanne Kurtzberg, MD, Julie Lopez, MD 2020-06-01
To Study Clinical Characteristics, Treatment Outcome of Coronavirus (COVID-19) Patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) CIMS Hospital Pvt. Ltd. India 2020-05-26 COVID-19/20-01, CTRI/2020/05/025247 Phase Not Applicable Not yet recruiting 1 500 Dr Amit Patel, Dr Hardik Shah, Dr Surabhi Madan 2020-05-28
To Study effectiveness and outcomes of Unani Medicine prophylactic interventions on population at risk of COVID-19 Coronavirus disease 19 infection Variable regimens including Khameera Marwareed , Tiryaq-e-Arba , Unani Joshanda Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Central Council for Research in Unani Medicine India 2020-05-29 CCRUM 05/2020/01, CTRI/2020/05/025254 Phase 3 Clinical Not yet recruiting 7 40000 Dr Ahmad Minhajuddin, Dr Arsheed Iqbal, Dr H A Lari, Dr Maqbool Ahmed, Dr Naheed Parveen, Dr Parvez Khan, Dr Pradeep Kumar, Dr Shagufta Parveen, Prof Abdul Wadood, Prof Asim Ali Khan 2020-05-29
An observational study on QT interval changes with Hydroxychloroquine used as prophylaxis in COVID exposure risk individuals Coronavirus disease 19 infection hydroxychloroquine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Vydehi Institute of Nursing Sciences & Research CentreVydehi Institute of Nursing Sciences & Research Centre India 2020-06-15 CTRI/2020/05/025289 Phase Not Applicable Not yet recruiting 1 50 P Vamsavardhana Reddy 2020-05-28
The Utility of Bedside Lung Ultrasonography on Diagnosis of COVID-19 Coronavirus disease 19 infection, Viral pneumonia lung ultrasound alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Istanbul Bakirkoy Maternity and Children Diseases Hospital Turkey 2020-05-10 2020-09-10 KSSEAH--, NCT04399681 Phase Not Applicable Recruiting 1 4 Months 100 Ramazan Guven, Seda Yilmaz Semerci 2020-05-26
Impact of effect of Ayurvedic treatment on novel Corona virus disease Coronavirus disease 19 infection Variable regimens including Anu Taila , Ashwagandha , Giloy Extract , Swasari Ras , Tulsi Extract Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) NIMS University, Patanjali Research Foundation India 2020-05-29 CTRI/2020/05/025273 Phase 2 Clinical Recruiting 1 120 Dr Abhishek Sharma, Dr Ganpat Devpura 2020-05-28
HPCOV-19: A study to assess the efficacy of Homoeopathic medicine in the prevention of Covid-19 Coronavirus disease 19 infection Arsenicum album 30 alone Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) District Homeopathic Medical Office India 2020-05-30 CTRI/2020/05/025272, HPCOV-19 Phase 3 Clinical Not yet recruiting 1 800 Dr Boban J, Dr Pramod P, Dr S Balamani 2020-05-28
Corona virus in tears Coronavirus disease 19 infection, SARS coronavirus infection Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Maulana Azad Medical College India 2020-05-24 CTRI/2020/05/025291 Phase Not Applicable Not yet recruiting 1 70 Dr RITU ARORA 2020-05-26
Ozone Therapy in the Prevention of COVID-19 Infection Coronavirus disease 19 infection Turkozone Blue-S medical ozone generator alone, ozone therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Marmara University Turkey 2020-05-06 2020-05-17 2761, NCT04400006 Phase Not Applicable Completed 1 71 Kardelen Gencer 2020-05-26
CIRCA-19: Cellular Immuno-Therapy for COVID-19 Acute Respiratory Distress Syndrome - Vanguard Coronavirus disease 19 infection, Respiratory distress syndrome allogeneic bone marrow-derived mesenchymal stem cell therapy (iv, septic shock/COVID-19/ADRS), Ottawa Hospital Research Institute alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ottawa Hospital Research Institute Stem Cell Network Canada 2020-05-31 2021-06-30 20200243-01H, CIRCA-19, NCT04400032 Phase 1 Clinical Not yet recruiting 1 13 Months 9 Bernard Thebaud, MD, David Courtman, PhD, Dean Fergusson, PhD, Duncan J Stewart, MD, Manoj Lalu, MD, Shane English, MD 2020-06-01
Siddha Intervention Population Study Coronavirus disease 19 infection Kabasurakudineer Nilavembukudineer alone Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Central Council for Research in Siddha Ministry of Ayush India 2020-05-25 CTRI/2020/05/025298 Phase Not Applicable Not yet recruiting 1 21500 DrKKanakavalli, PSathiyarajeswaran 2020-05-26
Study to assess efficacy of Ivermectin as prophylaxis of COVID -19 Coronavirus disease 19 infection ivermectin alone Chloride channel modulator Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) RD Gardi Medical College India 2020-05-27 CTRI/2020/05/025333 Phase 2 Clinical Not yet recruiting 1 2000 Dr Ashish Pathak, Dr Sunil Rathi 2020-06-02
The effects of Ginger on clinical manifestations and paraclinical features of patients with COVID-19: A randomized, double-blind, placebo-control clinical trial Coronavirus disease 19 infection Vomigone (Dineh Iran Pharmaceutical Company) alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bandare-abbas University of Medical Sciences Iran 2020-05-21 IR.HUMS.REC.1399.130, IRCT20200506047323N1 Phase 3 Clinical Recruiting 1 84 Mohammad Fathalipour, Parivash Davoodian, Teamur Aghamolaei 2020-05-26
Ayurveda as Prophylaxis for Suspected COVID-19 Patients Coronavirus disease 19 infection Ayurveda traetment alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) British Ayurvedic Medical Council All Party Parliamentary Group - Indian Traditional Sciences, Warwick University UK 2020-06-10 2020-10-01 BAMC01, NCT04395976 Phase Not Applicable Not yet recruiting 1 3 Months 120 Amarjeet S Bhamra, Avtar Singh, Jaydeep Joshi, Mahesh Mathpati, Mauroof Anthique, Neha Sharma, Shantha Godagama, Venkata Joshi, Vishwes Kulkarni 2020-05-26
Investigating the efficacy and safety of N-Acetyl Cysteine (NAC) inhalation spray in controlling the symptoms of patients with COVID-19 Coronavirus disease 19 infection N-acetyl-cysteine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bagheiat-allah University of Medical Sciences Iran 2020-05-13 IR.BMSU.REC.1399.123, IRCT20080901001165N55 Phase 3 Clinical Recruiting 1 72 Dr. Rezaeiyan, Mostafa Ghanei, Parisa Kianpour, Yunes Panahi 2020-05-26
Vitamin D and COVID-19: Evaluation of the likely beneficial effects of vitamin D on infection with coronavirus Coronavirus disease 19 infection cholecalciferol alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundación Para La Investigación E Innovación Biosanitaria En El Principado De Asturias (Finba) Spain 2020-05-19 2020-002274-28, COVID-VIT-D, Vitamin D and COVID-19 Phase 4 Clinical Recruiting 1 60 Managing director 2020-05-27
Convalescent Plasma in the treatment of 6 COVID-19 Patients Coronavirus disease 19 infection convalescent plasma alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Affiliated Hospital of Zunyi Medical College, Guizhou Provincial Jiangjunshan Hospital China 2020-01-29 2020-04-30 ChiCTR2000033056 Phase 0 Clinical No longer recruiting 1 3 Months 6 Zhang Wei 2020-05-27
The research of novel coronavirus pneumonia (COVID-19) patients' immune status and severity of disease Coronavirus disease 19 infection, Viral pneumonia Human immunoglobulin alone, Xuebijing alone, Human immunoglobulin plus Xuebijing Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) First Hospital of Changsha China 2020-03-01 2021-03-01 ChiCTR2000033190 Phase 0 Clinical No longer recruiting 1 12 Months 60 Ailian Lv, Yuanlin Xie 2020-05-27
Novel coronavirus pneumonia (COVID-19) and Symptomatic Venous Thromboembolism: a Multicenter Retrospective Study Coronavirus disease 19 infection, Viral pneumonia Union Hospital Tongji Medical School Huazhong University Of Science & Technology National Natural Science Foundation of China China 2020-05-20 2020-05-30 ChiCTR2000033055 Phase Not Applicable Not yet recruiting 15 300 Liang Tang, Yu Hu 2020-06-02