Last updated: Jun 19, 2020 - 02:00 BST
| CRITICAL: Crizanlizumab for Treating COVID-19 Vasculopathy |
Coronavirus disease 19 infection, Inflammatory disease, Respiratory tract infection, Thrombosis, Vascular disease |
crizanlizumab alone |
P selectin antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Johns Hopkins University |
Brigham & Women's Hospital, Novartis AG, SOCAR Research SA |
US |
2020-06-30 |
2020-10-31 |
CRITICAL, IRB00249874, NCT04435184 |
Phase 2 Clinical |
Not yet recruiting |
0 |
4 Months |
40 |
Charles J Lowenstein, MD, Charles Lowenstein, MD, Shannon Kelley, BS, Thorsten Leucker, MD PhD |
2020-06-18 |
| A study of 254 nm UVC ray therapy in pharynx for asymptomatic to mild cases of coronavirus disease |
Coronavirus disease 19 infection |
standard of care alone, ultraviolet C therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Akshardeep Eye Hospital |
|
India |
2020-06-11 |
|
CTRI/2020/06/025766 |
Phase Not Applicable |
Not yet recruiting |
0 |
|
300 |
Dr Jagdeep Kakadia |
2020-06-18 |
| SIDCOVID: A randomized, controlled clinical trial to determine the efficacy of siddha drugs in COVID-19 patients |
Coronavirus disease 19 infection |
Variable regimens including Amukkara choornam , Kabasura kudineer , Thalisathi choornam , adathodai manappagu |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Institute of Siddha |
|
India |
2020-06-15 |
|
CTRI/2020/06/025763, SIDCOVID |
Phase 2 Clinical |
Not yet recruiting |
0 |
|
150 |
G J Christian, Meenakumari R |
2020-06-18 |
| COVIDOLIP: Lipid Metabolism in COVID-19 Severe Pneumonia Compared With Severe Pneumonia Caused by Other Pathogen |
Coronavirus disease 19 infection, Inflammatory disease, Obesity, Sepsis, Viral pneumonia |
biological assays alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire Dijon |
|
France |
2020-04-07 |
2020-05-07 |
COVIDOLIP, NCT04435223, NGUYEN AOIC 2020 |
Phase Not Applicable |
Completed |
0 |
1 Month |
62 |
|
2020-06-18 |
| CoVPN 5001: A Study of Immune Responses to the Virus That Causes COVID-19 |
Coronavirus disease 19 infection |
sample collection alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Institute of Allergy and Infectious Diseases |
|
US, Botswana, Zambia, Kenya, Mexico, Peru, Tanzania, Zimbabwe, South Africa, Mozambique, Malawi, Argentina, Brazil |
2020-06-11 |
2021-01-31 |
5UM1AI068614-14, COVPN 5001, CoVPN 5001, NCT04431414 |
Phase Not Applicable |
Recruiting |
62 |
7 Months |
800 |
CRS Coodinator, CRS Coordinator, CRS Coorindator, CRS Leader, Clinical Trials Manager, Protocol Team Leader, Will Hahn |
2020-06-18 |
| A case report to evaluate the efficacy of recombinant tissue plasminogen activator (rt-PA) and tocilizumab in patients with COVID-19 |
Coronavirus disease 19 infection, Respiratory failure, Thrombosis |
recombinant tissue plasminogen activator (rt-PA) alone, tocilizumab alone |
|
Male, Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University General Hospital of Larissa |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
1 |
|
2020-06-18 |
| COVIT-EHPAD: COVID-19 and Vitamin D in Nursing-home |
Coronavirus disease 19 infection |
vitamin D3 alone |
|
Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital, Angers |
|
France |
2020-03-15 |
2020-05-15 |
2020/67, COVIT-EHPAD, NCT04435119 |
Phase Not Applicable |
Completed |
1 |
2 Months |
96 |
Cédric ANNWEILER, MD, PhD |
2020-06-18 |
| The Utility of Camostat Mesylate in Patients With COVID-19 Associated Coagulopathy (CAC) and Cardiovascular Complications |
Blood clotting disorder, Coronavirus disease 19 infection, Deep vein thrombosis, Heart injury, Hypoxia, Lung embolism |
camostat mesylate alone |
Serine protease inhibitor, Transmembrane serine protease 2 inhibitor, Trypsin inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Yale University |
Ono Pharmaceutical Co Ltd |
US |
2020-08-01 |
2021-07-30 |
2000028279, NCT04435015 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
0 |
11 Months |
200 |
Arpita Neogi, MS, Arya Mani, MD |
2020-06-18 |
| Local application of Povidone Iodine solution in nose and oral gargle for house hold contacts of COVID19 cases |
Coronavirus disease 19 infection |
gargle alone, povidone iodine alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
All India Institute of Medical Sciences, Mangalagiri |
|
India |
2020-06-30 |
|
CTRI/2020/06/025928 |
Phase Not Applicable |
Recruiting |
2 |
|
204 |
Dr Limalemla Jamir, Dr Sumita Shankar, Dr Vivekanand Kattimani |
2020-06-18 |
| Maraviroc in SARS-CoV-2 |
Coronavirus disease 19 infection, Viral pneumonia |
maraviroc alone |
CCR5 chemokine antagonist, CD4 agonist, HIV-1 gp120 protein inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Rhode Island Hospital |
|
US |
2020-09-30 |
2020-12-31 |
1611471-1, NCT04435522 |
Phase 0 Clinical |
Not yet recruiting |
1 |
3 Months |
16 |
Anshul Parulkhar, MD, Neel S Belani, MD, Philip A Chan, MD |
2020-06-18 |
| A medical records based retrospective study of novel coronavirus pneumonia (COVID-19) patients |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
Renmin Hospital of Wuhan University, West China Hospital |
Ministry of Science and Technology of the People´s Republic of China |
China |
2020-06-18 |
2021-06-18 |
ChiCTR2000033782 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
1400 |
Jirong Yue |
2020-06-18 |
| Compassionate Use of Opaganib in Patients With Coronavirus Disease 2019 (COVID-19) |
Coronavirus disease 19 infection |
opaganib alone, standard of care alone |
Dihydroceramide delta 4 desaturase inhibitor, Sphingosine kinase 2 inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shaare Zedek Medical Center |
|
Israel |
2020-04-03 |
2020-05-15 |
0123-20- SZMC, NCT04435106 |
Phase Not Applicable |
Completed |
1 |
1 Month |
23 |
|
2020-06-18 |
| Efficacy and Safety of Nitazoxanide for Post Exposure Prophylaxis of COVID-19 |
Coronavirus disease 19 infection |
nitazoxanide alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Azidus Brasil |
Farmoquimica SA |
Brazil |
2020-06-30 |
2020-08-31 |
NCT04435314, NITFQM0620OR |
Phase 2 Clinical |
Not yet recruiting |
1 |
2 Months |
200 |
Luciana Ferrara, Marcelo Fonseca, MD, Reginaldo Raimundo Fujita |
2020-06-18 |
| Study on predictors of novel coronavirus pneumonia (COVID-19) elderly patients |
Coronavirus disease 19 infection, Sarcopenia, Viral pneumonia |
|
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
West China Hospital |
Ministry of Science and Technology of the People´s Republic of China |
China |
2020-06-18 |
2020-09-01 |
ChiCTR2000033781 |
Phase Not Applicable |
Not yet recruiting |
1 |
2 Months |
114 |
Jirong Yue, Yao Ma |
2020-06-18 |
| A Phase I/II study to evaluate its tolerability and activity in COVID-19 patients with hypoxemic respiratory failure receiving either non-invasive positive pressure ventilation (NIPPV) or mechanical ventilation (MV) |
Coronavirus disease 19 infection, Lung inflammation, Respiratory failure |
Rejuveinix alone, mechanical ventilation alone, non-invasive positive pressure ventilation alone, standard of care alone |
|
|
Reven Pharmaceuticals Inc |
|
|
|
|
|
Phase 1/Phase 2 Clinical |
Planned |
0 |
|
|
|
2020-06-18 |
| Inhaled Ciclesonide for Outpatients With COVID19 |
Coronavirus disease 19 infection |
ciclesonide alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
McGill University Health Center, Research Institute of the McGill University Health Centre |
|
Canada |
2020-06-25 |
2021-03-25 |
2021-6696, NCT04435795 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
9 Months |
454 |
Nicole Ezer, Rola Hamed |
2020-06-18 |
| STORM: Repurposing Old Drugs TO Suppress a Modern Threat: COVID-19 STORM |
Coronavirus disease 19 infection |
doxycycline hyclate alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Temple University |
|
US |
2020-07-31 |
2021-07-31 |
NCT04433078, STORM, THE STORM TRIAL |
Phase 2 Clinical |
Not yet recruiting |
1 |
12 Months |
240 |
Arthur M Feldman, MD, PhD, Jamie L Garfield, MD |
2020-06-18 |
| A Phase I Study to Assess BAT-2020 in Hospitalized Patients Infected With SARS-CoV-2 (COVID-19) |
Coronavirus disease 19 infection |
BAT-2020 alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Bio-Thera Solutions Ltd |
|
|
2020-07-20 |
2021-01-18 |
BAT2020-001-CR, NCT04432766 |
Phase 1 Clinical |
Not yet recruiting |
0 |
5 Months |
174 |
|
2020-06-18 |
| A medical records based study for analysis of Tongue Features of novel coronavirus pneumonia (COVID-19) Patients |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
Dahuashan Cabin Hospital, Jiangxia District, Evidence-Based medicine center, Tianjin University of Traditional Chinese Medicine |
Tianjin University of Traditional Chinese Medicine |
China |
2020-06-11 |
2020-06-19 |
ChiCTR2000033780, ChiMCTR2000003393 |
Phase Not Applicable |
No longer recruiting |
1 |
|
500 |
Junhua Zhang, Wentai Pang |
2020-06-18 |
| Age and viral load in COVID-19 patients |
Coronavirus disease 19 infection, SARS coronavirus infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
St Marianna University School of Medicine |
|
Japan |
2020-06-18 |
|
UMIN000040816 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
30 |
Tomohiro Katsuta |
2020-06-18 |
| An observational, retrospective study to explore the epidemiological information, clinical characteristics, therapeutic outcomes and temporal progression of laboratory findings in 2019-coronavirus disease (COVID-19) patients exposed to lopinavir |
Coronavirus disease 19 infection |
lopinavir alone |
|
|
The 6th People's Hospital of Hangzhou |
|
China |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
10 |
|
2020-06-18 |
| Physical Rehabilitation in ICU in ARDS Patients With COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
Rehabilitation program alone, Standard care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Koc University |
|
Turkey |
2020-03-15 |
2020-06-11 |
2020.169.IRB1.037, NCT04435080 |
Phase Not Applicable |
Completed |
1 |
2 Months |
35 |
Ozden Ozyemisci Taskiran, Prof |
2020-06-18 |
| IDRA-COVID19: Ivermectin versus Combined Hydroxychloroquine and Antiretroviral Drugs (ART) Among Asymptomatic COVID-19 |
Coronavirus disease 19 infection |
ivermectin alone |
Chloride channel modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Mahidol University |
|
Thailand |
2020-07-31 |
2021-11-30 |
323/2563 (IRB3), IDRA-COVID19, NCT04435587 |
Phase 4 Clinical |
Not yet recruiting |
1 |
16 Months |
80 |
Rujipas Sirijatuphat, MD, Yupin Suputtamongkol, Yupin Suputtamongkol, MD |
2020-06-18 |
| A retrospective study on arbidol monotherapy was superior to lopinavir/ritonavir in treating COVID-19 |
Coronavirus disease 19 infection |
arbidol alone, lopinavir + ritonavir alone |
HIV protease inhibitor |
|
The Third People’s Hospital of Changzhou |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
50 |
|
2020-06-18 |
| RESCUE1-19: Best Supportive Care With or Without Low Dose Whole Lung Radiation Therapy for the Treatment of COVID-19 |
Coronavirus disease 19 infection |
Low Dose Radiation Therapy (LDRT) alone, best supportive care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Emory University |
|
US |
2020-06-12 |
2022-05-30 |
NCI-2020-04061, NCT04433949, P30CA138292, RAD5049-20, RESCUE1-19, STUDY00000781 |
Phase 3 Clinical |
Recruiting |
1 |
23 Months |
52 |
Allyson Anderson, Autumn Lunceford, Clayton B Hess, MD, MPH, Clayton B. Hess, MD,MPH, Mohammad K Khan, MD, PhD, Mohammad K. Khan, MD, PhD |
2020-06-18 |
| The effect of vitamin C and E in the treatment and clinical course of patients with SARS-COV2 (COVID-19) |
Coronavirus disease 19 infection |
hydroxychloroquine diet alone, Variable regimens including hydroxychloroquine sulfate , lopinavir + ritonavir , vitamin C , vitamin E |
HIV protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Isfahan University of medical Sciences |
|
Iran |
2020-04-20 |
|
IR.MUI.MED.REC.1399.047, IRCT20180425039414N3 |
Phase 2/Phase 3 Clinical |
No longer recruiting |
1 |
|
80 |
Atousa Hakamifard, Shghayegh Haghjoo Javanmard |
2020-06-18 |
| A multinational registry analysis of the use of hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19 |
Coronavirus disease 19 infection |
chloroquine alone, hydroxychloroquine alone, macrolide alone, chloroquine plus hydroxychloroquine |
|
|
Harvard Medical School |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
96032 |
|
2020-06-18 |
| Evaluating the Efficacy and Safety of Bromhexine Hydrochloride Tablets in Treating Pediatric novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Standard treatment alone, bromhexine hydrochloride alone |
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Children's Hospital of Zhejiang University School of medicine |
Zhejiang Wanbang Pharmaceutical Co Ltd |
China |
2020-02-12 |
2020-12-31 |
ChiCTR2000033774 |
Phase 4 Clinical |
Not yet recruiting |
1 |
10 Months |
30 |
Qingqing Wang, Zhimin Chen |
2020-06-18 |
| Treatment With Investigational Convalescent Plasma and Measure Antibody Levels in Patients Hospitalized With COVID-19 |
Coronavirus disease 19 infection |
Anti-SARS-CoV-2 convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of New Mexico |
|
US |
2020-04-28 |
2025-04-28 |
20-227, NCT04434131 |
Phase 2 Clinical |
Recruiting |
1 |
60 Months |
30 |
Greg Mertz, MD, Michelle Harkins, MD |
2020-06-18 |
| A retrospective, single center study on treatment response of tocilizumab in COVID-19 |
Coronavirus disease 19 infection |
tocilizumab alone |
|
|
Huazhong University of Science and Technology |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
15 |
|
2020-06-18 |
| Clinical study on the effect of Keganliyan oral liquid on the relief of pharyngeal symptoms of novel coronavirus pneumonia (COVID-19) in convalescence, suspected patients and other susceptible populations |
Coronavirus disease 19 infection |
Keganliyan liquid alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Maoming Affiliated Hospital of Southern Medical University |
|
China |
2020-06-15 |
2020-12-31 |
ChiCTR2000033745 |
Phase 4 Clinical |
Not yet recruiting |
1 |
6 Months |
240 |
Guanying Hu, Yaocai Li |
2020-06-18 |
| A study for long-term prognosis in hospitalized novel coronavirus pneumonia (COVID-19) patients |
Coronavirus disease 19 infection |
|
|
|
China-Japan Friendship Hospital, Wuhan Jinyintan Hospital |
China Academy of Chinese Medical Sciences |
China |
2020-05-01 |
2021-05-01 |
ChiCTR2000033723 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
2500 |
LIU YING, Zhang DY, Huang CL, Cao B |
2020-06-18 |
| Seroconversion Among Staff at a Large Acute Care Hospital in Denmark During the COVID-19 Pandemic |
Coronavirus disease 19 infection |
biological sampling alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Nordsjaellands Hospital |
Nykøbing Falster County Hospital, University of Oxford |
Denmark |
2020-03-27 |
2025-08-01 |
JOURNAL-NR.: H-20022312, NCT04431310 |
Phase Not Applicable |
Recruiting |
2 |
64 Months |
300 |
Fischer, Gry St-Martin, md, Thea K Fischer, Thea K Fischer, professor |
2020-06-18 |
| CARAVAN: Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of Remdesivir (GS-5734) in Participants From Birth to < 18 Years of Age With Coronavirus Disease 2019 (COVID-19) |
Coronavirus disease 19 infection |
remdesivir alone |
COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator |
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Gilead Sciences Inc |
|
|
2020-06-30 |
2020-12-31 |
2020-001803-17, CARAVAN, GS-US-540-5823, NCT04431453 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
0 |
6 Months |
52 |
Gilead Clinical Study Information Center, Gilead Study Director |
2020-06-18 |
| An observational study to evaluate the pharmacokinetics of favipiravir in patients with severe COVID-19 who were admitted to the intensive care unit and placed on mechanical ventilation |
Coronavirus disease 19 infection |
favipiravir alone |
RNA polymerase inhibitor |
|
Kobe City Medical Center General Hospital, Kobe Gakuin University |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
7 |
|
2020-06-18 |
| Assessment of the Effectiveness of Vibroacoustic Therapy for Respiratory Failure Caused by COVID 19 |
Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure, Viral pneumonia |
VibroLUNG alone, vibroacoustic therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Astana Medical University |
|
Kazakhstan |
2020-03-22 |
2021-02-01 |
ASTANAMU, NCT04435353 |
Phase Not Applicable |
Recruiting |
2 |
10 Months |
200 |
Irina Mukatova, MD, Irina Mukatova, PhD, Ivan Vahrushev, Dr, Mukatova Irina |
2020-06-18 |
| Impact of Cancellation of Non-urgent Surgical Cases on Patients During the COVID-19 Pandemic |
Coronavirus disease 19 infection |
|
|
|
Mansoura University |
|
Egypt |
2020-07-01 |
2020-12-01 |
NCT04433312, SURG RES COL 2 |
Phase Not Applicable |
Not yet recruiting |
1 |
5 Months |
10000 |
Ahmed M Elsheikh, MD,MBA,CMQOE, Hosam Hamed, MD, MSc, PhD, Mostafa M Shalaby, MD, MSc, PhD, Mostafa Shalaby, MD, MSc, PhD |
2020-06-18 |
| Study to Assess VPM-1002 in Reducing Hospital Admissions and/or Severe Respiratory Infectious Diseases in Elderly in COVID-19 Pandemic |
Coronavirus disease 19 infection, Respiratory tract infection |
VPM-1002 alone |
Listeriolysin stimulator |
Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Max-Planck Gesellschaft zur Förderung Der Wissenschaften eV, Vakzine Projekt Management GmbH |
FGK Clinical Research GmbH |
Germany |
2020-06-30 |
2021-05-31 |
2020-001675-33, NCT04435379, VPM1002-DE-3.07COV |
Phase 3 Clinical |
Recruiting |
4 |
11 Months |
2038 |
Leander Grode, Dr. rer. nat. |
2020-06-18 |
| PEDONCOVID: COVID-19 in Pediatric Oncology and Hematology Centers in France |
Cancer, Coronavirus disease 19 infection |
|
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Caen University Hospital |
|
France |
2020-04-27 |
2023-04-27 |
20-065, NCT04433871, PEDONCOVID |
Phase Not Applicable |
Recruiting |
0 |
36 Months |
300 |
Jérémie M Rouger-Gaudichon, MD, PhD, Jérémie Rouger-Gaudichon, MD, PhD |
2020-06-18 |
| PrimaryCovCare: Ambulatory healthcare models and processes during the ongoing SARS-CoV-2 pandemic (COVID-19) |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Heidelberg |
|
Germany |
2020-06-17 |
|
DRKS00022224, PrimaryCovCare, S-418/2020 |
Phase Not Applicable |
Recruiting |
1 |
|
1000 |
Amanda Breckner, Catharina Roth, Michel Wensing, Sandra Stengel |
2020-06-18 |
| To evaluate the efficacy of diammonium glycyrrhizinate in combination with vitamin C in patient with COVID-19 |
Coronavirus disease 19 infection |
diammonium glycyrrhizinate plus vitamin C |
|
Female |
National Institute of Allergy and Infectious Diseases, National Institute of General Medical Sciences, National Institutes of Health, US Department of Health and Human Services |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
1 |
|
2020-06-18 |
| A clinical trial of VLP vaccine (COVID-19), Saiba for the potential prevention of SARS-CoV-2 infection (COVID-19) |
Coronavirus disease 19 infection |
VLP vaccine (COVID-19), Saiba alone |
COVID19 Spike glycoprotein modulator |
|
Saiba GmbH |
|
|
2020-12-31 |
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-06-18 |
| IFORS: A Study to Compare the Efficacy and Safety of Different Doses of Ivermectin for COVID-19 |
Coronavirus disease 19 infection, Respiratory disease, Respiratory tract infection |
ivermectin alone |
Chloride channel modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fundação Universidade Federal De São Carlos |
|
Brazil |
2020-07-01 |
2021-07-01 |
IFORS, IFORS, NCT04431466 |
Phase 2 Clinical |
Not yet recruiting |
0 |
12 Months |
64 |
Henrique Pott Junior, Henrique Pott Junior, MD PhD |
2020-06-18 |
| Cardiovascular Implications of COVID-19 |
Coronavirus disease 19 infection, Heart injury |
[1-13C] pyruvate alone, multiparametric cardiac magnetic resonance imaging (CMR) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Texas Southwestern Medical Center |
|
|
2020-06-30 |
2020-10-31 |
NCT04435457, STU-2020-0359 |
Phase Not Applicable |
Not yet recruiting |
0 |
4 Months |
70 |
Carolyn Kelly, RN, MPH, CCRC, Justin L Grodin, MD, MPH |
2020-06-18 |
| To observe the effect of Siddha formulation Kabasura kudineer in COVID 19 patients |
Coronavirus disease 19 infection |
Kabasura kudineer alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Government Theni Medical College and Hospital, Ministry of Ayush |
|
India |
2020-06-24 |
|
CTRI/2020/06/025874 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
60 |
Dr C Anbarasi, Dr P Sankararaj |
2020-06-18 |
| A phase II/III study of COVAX-19 in prevention of COVID-19 |
Coronavirus disease 19 infection |
Covax-19 alone |
Coronavirus spike glycoprotein inhibitor |
|
Vaxine Pty Ltd |
|
|
2020-12-31 |
|
|
Phase 2/Phase 3 Clinical |
Planned |
0 |
|
|
|
2020-06-18 |
| Study of AYUSH KWATH in quarantine persons |
Coronavirus disease 19 infection |
Ayush Kwath alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Dr. Sarvepalli Radhakrishnan Rajasthan Ayurveda University |
|
India |
2020-06-17 |
|
CTRI/2020/06/025779 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
50 |
Prof Dr Abhimanyu Kumar |
2020-06-18 |
| A case series, retrospective study on 18F-FDG PET/CT findings of COVID-19 infection |
Coronavirus disease 19 infection, Respiratory disease |
18F-FDG alone, positron emission tomography/computed tomography alone |
|
|
Chang Gung Memorial Hospital, Huazhong University of Science and Technology, Hubei Province Pharmaceutical Industry Research Institute |
|
China |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
4 |
|
2020-06-18 |
| A retrospective, multicenter, cohort study to describe the association between use of hydroxychloroquine, with or without azithromycin, and clinical outcomes among hospital inpatients diagnosed with coronavirus disease 2019 (COVID-19) |
Coronavirus disease 19 infection |
azithromycin alone, hydroxychloroquine alone, azithromycin plus hydroxychloroquine |
|
|
UAlbany School of Public Health |
|
US |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
1438 |
|
2020-06-18 |
| A prophylactic interventional study to determine the possible protective effect of Siddha Polyherbal formulation Kabasura Kudineer / Nilavembu kudineer against the COVID-19 on intermittent, month-long consumption by Highrisk population and frontline workers in Tamil Nadu, India |
Coronavirus disease 19 infection |
Standard of Care alone, Kabasura Kudineer plus Nilavembu kudineer |
|
|
National Institute of Siddha |
|
India |
2020-06-15 |
|
CTRI/2020/06/025769 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
500 |
Dr G J Christian, Dr R Meenakumari |
2020-06-18 |
| TOCCIP: COVID-19 Critically Ill Patients Evolution After Medical Transport by Train From Paris Intensive Care Units to West of France Intensive Care Units |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Rennes University Hospital |
|
France |
2020-06-30 |
2020-09-30 |
35RC20-3091-TOCCIP, NCT04433325, TOCCIP |
Phase Not Applicable |
Not yet recruiting |
0 |
3 Months |
150 |
Anne Ganivet, Arnaud THILLES, Benoît Painvin, Nicolas Mevel, Stéphane ERHMANN |
2020-06-18 |
| Impact of COVID-19 on Laboratory Professionals-Early Evidences from a Survey at a Clinical Chemistry Laboratory in a Developing Country |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Aga khan University |
|
Pakistan |
2020-06-04 |
2020-06-14 |
ChiCTR2000033899 |
Phase Not Applicable |
No longer recruiting |
1 |
|
64 |
Sibtain Ahmed |
2020-06-18 |
| An open-label, Randomized Controlled Clinical trial to Evaluate the Safety and Efficacy of selected Siddha formulations in patients diagnosed with COVID-19 |
Coronavirus disease 19 infection |
siddha formulation alone, Variable regimens including Kabasura kudineer , Nellikai Ilagam , amukkara churnam |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Chengalpattu Medical College, National Institute of Siddha |
|
India |
2020-06-20 |
|
CTRI/2020/06/025768 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
200 |
Dr G J CHRISTIAN, Dr MEENAKUMARI R |
2020-06-18 |
| Natural Language Processing (NLP) Analysis of Free Text Notes to Investigate Coronavirus (COVID-19) |
Coronavirus disease 19 infection, Renal injury, Thromboembolism |
electronic health record (EHR) alone, natural language processing techniques alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cambridge University Hospitals NHS Foundation Trust |
University of Cambridge |
UK |
2020-07-31 |
2021-07-31 |
A095625, NCT04432961 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
200 |
Dr Sapna Trivedi |
2020-06-18 |
| An interim Doherty Report on SARS-CoV-2 antibodies based on Wondfo test (serology-based COVID-19 POC test) |
Coronavirus disease 19 infection |
Wondfo test (serology-based COVID-19 POC test) alone |
|
|
Cellmid Ltd |
|
Australia |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
137 |
|
2020-06-18 |
| The Use of Lung Ultrasonography in COVID-19 Patients |
Coronavirus disease 19 infection, Respiratory failure |
mechanical ventilator settings and position alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Gaziosmanpasa Taksim Research and Education Hospital |
|
Turkey |
2020-05-26 |
2020-06-26 |
GAZIOSMANPASA, NCT04432051 |
Phase Not Applicable |
Recruiting |
1 |
1 Month |
100 |
SİBEL BEKTAŞ |
2020-06-18 |
| Community Health Workers Against COVID19 |
Anxiety disorder, Coronavirus disease 19 infection |
community health worker support alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universitaet Gent |
|
Belgium |
2020-05-21 |
2020-10-30 |
BC-07744., NCT04426305 |
Phase Not Applicable |
Recruiting |
1 |
5 Months |
140 |
|
2020-06-18 |
| A Study of Favipiravir in Patients with Mild to Moderate Coronavirus Disease (COVID-19) |
Coronavirus disease 19 infection |
favipiravir alone, supportive care alone |
RNA polymerase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Cipla Ltd |
|
India |
2020-06-17 |
|
CP/04/20, Version No. 1.0, CTRI/2020/06/025799 |
Phase 3 Clinical |
Not yet recruiting |
8 |
|
156 |
Dr Ameet Dravid, Dr Anand Kumar, Dr Atul Patel, Dr Jaideep Gogtay, Dr Meenakshi Bhattacharya, Dr Raja Dhar, Dr Rohidas Borse, Dr Sandesh Sawant, Dr Shreepad Bhat, Dr Vasant Nagvekar, Mr Abhijit Vaidya |
2020-06-18 |
| ICON STUDY: A Clinical trial to establish the appropriate line of management of non-muscle invasive bladder cancers who have had their intravesical BCG therapy interrupted |
Bladder cancer, Coronavirus disease 19 infection |
BCG alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
All India Institute of Medical Sciences, All India Institute of Medical Sciences Bhubaneswar, Christian Medical College, Vellore, India, Jawaharlal Institute of Postgraduate Medical Education Research, Postgraduate Institute of Medical Education and Research, king george's medical university |
|
India |
2020-06-18 |
|
CTRI/2020/06/025798, ICON STUDY |
Phase 4 Clinical |
Not yet recruiting |
10 |
|
70 |
Amlesh Seth, Aneesh Srivastava, Dr Tushar Aditya Narain, Gautam Ram Choudhary, Manikandan Ramanidhatharan, Prasant Nayak, Sameer Trivedi, Santosh Kumar, Satya Narayan Sankhwar, Shrawan Kumar Singh, Tushar Aditya Narain |
2020-06-18 |
| Quality of Life During COVID-19 Lockdown |
Coronavirus disease 19 infection, Pain |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Cancer Institute, Jhajjar, AIIMS |
|
India |
2020-06-13 |
|
CTRI/2020/06/025797 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
|
Anuja Pandit |
2020-06-18 |
| Effect of aragwadhadi kwath (kadha in Hindi) in treatment of mild coronavirus disease |
Coronavirus disease 19 infection |
aragwadhadi kwath alone, standard care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Sanjivani Aryuvedic Centre |
|
India |
2020-06-15 |
|
CTRI/2020/06/025796 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
90 |
Dr Sunil Panjwani, Vaidhya Tushar Trivedi |
2020-06-18 |
| Effects of Lockdown during Corona Pandemic on Children with Neurodevelopmental Disorders-A Questionnaire Based Survey |
Attention deficit hyperactivity disorder, Autism, Coronavirus disease 19 infection |
question based survey alone |
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs) |
Army Hospital Research and Referral |
|
India |
2020-06-15 |
|
CTRI/2020/06/025795 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
150 |
J N Goswami, Shuvendu Roy |
2020-06-18 |
| Effect of anakinra in treatment of COVID-19 |
Coronavirus disease 19 infection |
anakinra, Persisgen alone, recommended COVID-19 treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Persisgen Par Co |
|
Iran |
2020-06-21 |
|
IR.SBMU.PHARMACY.REC.1399.051, IRCT20120703010178N20 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
30 |
Amir Behnam Kharazmi, Amir Hossein Karagah, Mohammad Sistanizad, Omid Moradi |
2020-06-17 |
| A Study to Assess the Effect of Beckman Coulter SARS-CoV-2 Antibody Test in Patients with COVID-19 |
Coronavirus disease 19 infection |
Beckman Coulter SARS-CoV-2 antibody test alone |
|
|
Henry Ford Health System |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
|
|
2020-06-17 |
| PRO-SERO-COV: Serological Response to SARS-Cov-2 Virus in Personnel of the Institut Bergonie in the Context of the COVID-19 Pandemic |
Coronavirus disease 19 infection |
blood sampling alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Institut Bergonie |
|
France |
2020-06-30 |
2021-12-31 |
2020-A01355-34, IB 2020-01, NCT04426006, PRO-SERO-COV |
Phase Not Applicable |
Not yet recruiting |
1 |
18 Months |
1000 |
Brice RICHEZ, MD, Simone MATHOULIN-PELISSIER, MD, PhD |
2020-06-18 |
| TA/SARS-Cov2: Is Adipose Tissue a Reservoir for SARS-Cov2 Spread in Covid-19 Patients? |
Coronavirus disease 19 infection |
biopsies of subcutaneous adipose tissue alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire De Nice |
|
France |
2020-07-01 |
2021-07-09 |
20-PP-15, NCT04427878, TA/SARS-Cov2 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
5 |
Berengère Chignon-Sicard, PH, Vanina OLIVERI, PM |
2020-06-18 |
| CIO: Impact of COVID-19 Lockdown on Obesity and Eating Behaviors |
Acute stress disorder, Anxiety disorder, Binge eating disorder, Coronavirus disease 19 infection, Depression, Obesity |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospices Civils De Lyon |
|
France |
2020-06-30 |
2020-09-30 |
2020-A01616-33, 69HCL20-0516, CIO, NCT04431284 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
46 |
Emmanuel DISSE, MD, Martine LAVILLE, MD |
2020-06-17 |
| ABACCuS: Antibody-Level Based Analysis of COVID Convalescent Serum |
Coronavirus disease 19 infection |
COVID-19 convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
William Beaumont Hospitals |
|
US |
2020-06-30 |
2021-08-31 |
2020-198, ABACCuS, NCT04432272 |
Phase 2 Clinical |
Not yet recruiting |
1 |
14 Months |
500 |
Matthew Sims, MD, Matthew Sims, MD PhD, Maureen Cooney, RN, BSN |
2020-06-18 |
| Favipiravir effectiveness in patients undergoing COVID19 Acute respiratory distress syndrome (ARDS) |
Coronavirus disease 19 infection, Respiratory distress syndrome |
favipiravir alone |
RNA polymerase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Masih Daneshvari Hospital |
|
Iran |
2020-03-20 |
2020-05-21 |
IR.SBMU.NRITLD.REC.1399.041, IRCT20150107020592N26 |
Phase 3 Clinical |
Completed |
1 |
2 Months |
20 |
DR Reza Masoodi, Seyed Mohammad Reza Hashemian, Seyyed Mohammadreza Hashemian |
2020-06-18 |
| Prone Positioning on Admission for Hospitalized COVID-19 Pneumonia Protocol |
Coronavirus disease 19 infection, Viral pneumonia |
Prone Positioning alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Poudre Valley Health System |
|
US |
2020-06-30 |
2020-12-31 |
20-6034, NCT04424797 |
Phase Not Applicable |
Recruiting |
3 |
6 Months |
100 |
Adam Jaskowiak, Lucie Uncapher, Lucie Uncapher, MD, Research Manager, Sara Twombly, MACI CCRC |
2020-06-18 |
| I-GLOBAL: Validation of an Immunochromatographic Assay for IgG/IgM Antibodies to 2019- nCoV |
Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia |
IgG/IgM rapid test cassette alone, immunochromatographic assay alone, polymerase chain reaction alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
European Institute of Oncology |
ASST Papa Giovanni XXIII, Azienda Ospedale Niguarda Cà Granda, Company Socio - Cremona Territorial Health, Fondazione IRCCS Istituto Neurologico Carlo Besta |
Italy |
2020-04-15 |
2020-12-31 |
I-GLOBAL, I-GLOBAL, NCT04434417 |
Phase Not Applicable |
Recruiting |
5 |
8 Months |
1000 |
Alberto Zambelli, MD, Antonio Marra, MD, Atanasio Nonis, PhD, Daniele Generali, MD, Francesco Di Meco, MD, Giuseppe Curigliano, MD, Giuseppe Curigliano, MD, PhD, Salvatore Siena, MD |
2020-06-18 |
| The effect of pentaglobin in the treatment of critically ill patients with COVID-19 |
Coronavirus disease 19 infection, Respiratory failure |
pentaglobin alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shaheed Beheshti Medical University |
|
Iran |
2020-03-20 |
|
IR.SBMU.NRITLD.REC.1399.014, IRCT20150107020592N27 |
Phase 3 Clinical |
Recruiting |
1 |
|
60 |
Dr Seyyed Mohamadreza Hashemian, Seyyed Mohammadreza Hashemian |
2020-06-18 |
| Proper Nutrition And Its Relation To Oral Diseases In Covid -19 Era |
Coronavirus disease 19 infection, Mouth disease |
Proper diet alone, Vitamins alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
October University for Modern Sciences and Arts |
|
Egypt |
2020-06-08 |
2020-06-28 |
12345678, NCT04434014 |
Phase Not Applicable |
Recruiting |
1 |
|
300 |
Lecturer Mona abdelmoteleb, Samah Kamel, A .Prof, Samah Mohamed Kamel, A.Prof, Samah Mohamed Kamel, associate professr, lecturer Mona Abdelmoteleb |
2020-06-18 |
| ASTANA: Oncological Surgery in Times of COVID-19: Effectiveness of Preoperative Screening for Sars-Cov-2 |
Cancer, Coronavirus disease 19 infection |
SARS-CoV-2 PT-PCR test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Instituto Brasileiro de Controle do Cancer |
|
Brazil |
2020-05-11 |
2020-12-31 |
33467320.0.0000.0072, ASTANA, NCT04434261 |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
1500 |
Alayne Yamada, PhD, Andre Lopes, MD |
2020-06-18 |
| Evaluation of the effectiveness of traditional medicine combination based on the Ferula assa-foetida gum - Tragacanth in Participants with Moderate to Severe Coronavirus Disease (COVID-19) |
Coronavirus disease 19 infection |
Ferula assa-foetida gum plus tragacanth |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Mashhad University of Medical Sciences |
|
Iran |
2020-06-19 |
|
IR.MUMS.REC.1399.285, IRCT20200607047675N1 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
100 |
Dr. Amin Bojdy, Dr. HamidReza Bahrami Taghanaki, Dr. Majid Jafarinejad, Nayereh Esmaeilzadeh, ِDr. Mohsen Tafaghdi |
2020-06-18 |
| Treatment of Severe and Critical COVID-19 Pneumonia With Convalescent Plasma |
Coronavirus disease 19 infection, Viral pneumonia |
anti sars-cov 2 convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
American British Cowdray Medical Center |
|
Mexico |
2020-06-19 |
2020-09-30 |
ABC-20-14, NCT04432103 |
Phase 3 Clinical |
Not yet recruiting |
1 |
3 Months |
36 |
Benjamín Valente, MD MSc DTMH, Francisco Moreno, MD, Irma Hoyo, MD PHD, Paulina Trápaga, MBE |
2020-06-18 |
| An interventional study to evaluate the safety and immune response of a vaccine against Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2, the virus that causes COVID-19 infection) when given to healthy adult participants |
Coronavirus disease 19 infection |
SARS-CoV-2 Sclamp alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
University of Queensland |
Coalition for Epidemic Preparedness Innovations |
Australia |
2020-07-14 |
|
ACTRN12620000674932p, UQ-1-SARS-CoV-2-Sclamp |
Phase 1 Clinical |
Not yet recruiting |
1 |
|
120 |
Dr Paul Griffin |
2020-06-18 |
| CoPE-HCP: COVID19 and Physical and Emotional Wellbeing of HCP |
Anxiety disorder, Coronavirus disease 19 infection, Depression, Psychotic disorder |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Queen Mary University of London |
|
UK |
2020-06-30 |
2021-06-30 |
284686, CoPE-HCP, NCT04433260 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
1050 |
Ajay Gupta, MD, PhD, Ajay Gupta, MD,PhD |
2020-06-18 |
| ACCOLADE: Amnion cells for COVID-19 related respiratory failure |
Coronavirus disease 19 infection, Respiratory failure |
amniotic epithelial cells (hAECs) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Monash Health |
|
Australia |
2020-06-29 |
|
ACCOLADE, ACTRN12620000676910p |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
|
40 |
A/Prof Rebecca Lim, Prof Yahya Shehabi |
2020-06-18 |
| Efficacy of Pentoxifylline as Add-on Therapy in COVID-19 Patients |
Coronavirus disease 19 infection |
pentoxifylline SR alone, standard treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
University of Sadat City |
|
Egypt |
2020-06-13 |
2020-08-30 |
NCT04433988, RC-6-2020 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
2 Months |
200 |
Mahmoud S Abdallah, PhD |
2020-06-18 |
| Perceptions, Representations and Experiences of Septic Isolation of Hospitalized Patients for COVID-19 Infection |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Intercommunal Creteil |
|
France |
2020-07-01 |
2020-07-15 |
ISOCOV, NCT04432922 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
15 |
Alice RAFFETIN, MD |
2020-06-18 |
| In-utero Vascular Accidents in Neonates From COVID-19 Infected Mothers |
Coronavirus disease 19 infection, Fetal growth restriction, Limb development disorder, Premature labor, Spontaneous abortion |
SARS-CoV-2 antibody testing alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Colorado, Denver, US |
|
US |
2020-07-31 |
2022-07-31 |
20-1399, NCT04431869 |
Phase Not Applicable |
Not yet recruiting |
1 |
24 Months |
200 |
Jose L Diaz-Miron, MD |
2020-06-17 |
| Validation of a Rapid Quantitative Test for Loss of Smell in COVID-19 Subjects |
Coronavirus disease 19 infection, Dysomia |
olfactory device alone, rapid quantitative olfactory smell test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Yale University |
|
US |
2020-06-15 |
2020-10-01 |
2000028259, NCT04431908 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
250 |
R Peter Manes, MD, FACS |
2020-06-18 |
| An Open-Label Randomized Controlled, Proof-of-Concept (PoC) Study to Evaluate the Safety and Efficacy of selected Siddha formulations in patients diagnosed with COVID-19 |
Coronavirus disease 19 infection |
Variable regimens including Amukkara choornam , KS kudineer , Nellikkai ilagam |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Institute of Siddha |
|
India |
2020-06-15 |
|
CTRI/2020/06/025762 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
200 |
Dr G J Christian, Dr R Meenakumari |
2020-06-17 |
| Population based cross-sectional study for COVID 19 prophylaxis with Polyherbal Siddha formulation Kabasura Kudineer / Nilavembu kudineer in containment zones and non containment zones during 2020 pandemic in Tamil Nadu, South India |
Coronavirus disease 19 infection |
Kabasura Kudineer / Nilavembu kudineer alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
National Institute of Siddha |
|
India |
2020-06-15 |
|
CTRI/2020/06/025761 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
10000 |
Dr G J Christian, Dr R Meenakumari |
2020-06-17 |
| A clinical trial to study the effect of drug named Sofosbuvir in hospitalized patients with COVID 19 |
Coronavirus disease 19 infection |
hydroxychloroquine plus sofosbuvir |
Hepatitis C virus NS5B polymerase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Vijaya Medical and Educational Trust |
|
India |
2020-06-17 |
|
CTRI/2020/06/025760 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
50 |
Babu N |
2020-06-18 |
| PoWerS: COVID-19 Psychological Wellbeing for Healthcare Students |
Coronavirus disease 19 infection |
Psychological wellbeing for healthcare workers alone |
|
Healthy volunteers accepted |
University of Nottingham |
|
|
2020-06-13 |
2020-12-30 |
NCT04429828, POWERS_JUNE2020, PoWerS |
Phase Not Applicable |
Not yet recruiting |
0 |
6 Months |
45 |
Holly Blake, PhD |
2020-06-18 |
| Hydroxychloroquine May Reduce Risk of COVID-19 Infection in Rheumatoid Arthritis Patients |
Coronavirus disease 19 infection, Rheumatoid arthritis |
glucocorticoid therapy alone, Variable regimens including hydroxychloroquine , leflunomide , methotrexate , sulfasalazine |
Dihydroorotate dehydrogenase inhibitor, Protein tyrosine kinase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
University of Sadat City |
|
Egypt |
2020-03-20 |
2020-06-20 |
IRB: RC-5-2020, NCT04434118 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
600 |
|
2020-06-18 |
| CAHMP-ED: COVID-19 and the Healthy Minds Program for Educators |
Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression |
Healthy Minds Program Foundations Training alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Wisconsin-Madison |
Center for Healthy Minds, Chan Zuckerberg Initiative, Healthy Minds Innovations |
|
2020-06-10 |
2022-06-30 |
2020-0533, A171600, CAHMP-ED, EDUC/COUNSELING PSYCH, NCT04426318, PROTOCOL APPROVAL 6/4/2020 |
Phase Not Applicable |
Not yet recruiting |
0 |
24 Months |
400 |
Corrina Frye, Simon B Goldberg, PhD |
2020-06-17 |
| A clinical study of nelfinavir in combination with amodiaquine for the treatment of COVID-19 |
Coronavirus disease 19 infection |
amodiaquine plus nelfinavir |
HIV protease inhibitor, HIV-1 protease inhibitor |
|
Norwegian University of Science and Technology (NTNU) |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-06-17 |
| Effect of Auriculotherapy in treatment of COVID-19 |
Coronavirus disease 19 infection |
orchicotherapy alone |
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Shahid Sadoughi University of Medical Sciences and Health Services |
|
Iran |
2020-04-28 |
|
IR.SSU..REC.1399.030, IRCT20180608040007N2 |
Phase Not Applicable |
Recruiting |
1 |
|
70 |
Dr. Masoud Mirzaei, Maryam Mohammadi, Mohammad Bagher Khani |
2020-06-18 |
| Dornase Alpha for the Treatment of COVID-19 |
Coronavirus disease 19 infection |
dornase alfa alone |
Deoxyribonuclease I stimulator, Deoxyribonuclease stimulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Acibadem University |
The Scientific and Technological Research Council of Turkey |
Turkey |
2020-05-25 |
2020-09-25 |
8820, NCT04432987 |
Phase 2 Clinical |
Recruiting |
1 |
4 Months |
60 |
Ercument Ovalı, MD, Ercument Ovalı, Prof. |
2020-06-18 |
| Effect of Atazanavir/Ritonavirin treatment of COViD-19 |
Coronavirus disease 19 infection |
atazanavir sulfate + ritonavir (HIV infection), Mylan Laboratories alone |
HIV protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Alborz University of Medical Science |
|
Iran |
2020-06-14 |
|
IR.ABZUMS.REC.1399.065, IRCT20200504047298N1 |
Phase 3 Clinical |
Recruiting |
1 |
|
100 |
Zeinab Siami |
2020-06-18 |
| ELIKYA COVID: Impact of SARS-CoV-2 Infection During Pregnancy on Newborns and Young Children |
Coronavirus disease 19 infection, Pregnancy disorder |
nasal swab test alone, serology test alone |
|
|
Centre Hospitalier Universitaire Saint Pierre |
Institute for Medical Immunology (IMI), Laboratoire Hospitalier Universitaire de Bruxelles |
Belgium |
2020-06-25 |
2024-06-30 |
ELIKYA COVID, ELIKYA COVID, NCT04432779 |
Phase Not Applicable |
Not yet recruiting |
1 |
48 Months |
3000 |
Julie Belhomme, MD, Tessa Goetghebuer, MD, Tessa Goetghebuer, MD PhD, Tessa Goetghebuer, MD, PhD |
2020-06-17 |
| HIBISCUS: A phase II/III pivotal, randomized, placebo-controlled Traumakine study in severely ill COVID-19 patients |
Adult respiratory distress syndrome, Coronavirus disease 19 infection, Influenza virus infection |
FP-1201 alone |
CD73 agonist, Interferon beta ligand |
|
Faron Pharmaceuticals Ltd |
|
US |
|
|
HIBISCUS |
Phase 2/Phase 3 Clinical |
Planned |
1 |
|
350 |
Prof. Daniel Talmor |
2020-06-17 |
| CovImmune 2: Study of the Incidence of SARS-CoV-2 Infection |
Coronavirus disease 19 infection |
blood sampling alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire De Nice |
|
France |
2020-07-15 |
2025-12-31 |
20-PP-14, CovImmune 2, NCT04429594 |
Phase Not Applicable |
Not yet recruiting |
1 |
65 Months |
1000 |
Barbara SEITZ, MCUPH, Barbara SEITZ- POLSKI, Christian PRADIER, barbara SEITZ POLSKI, sonia BOYER SUAVET |
2020-06-18 |
| COVID-19 Versus H1N1: Radiological Challenge During Next Influenza Season Rising |
Coronavirus disease 19 infection, Influenza virus infection, Viral pneumonia |
GE LightSpeed Plus 4 slice CT scanner (USA) alone, Philips Brilliant-16 (USA) alone, Siemens SOMATOM Sensation 64 (Germany) alone, Siemens SOMATOM Emotion 16 alone, Toshiba Aquilion 64 alone, Toshiba Aquilion CXL/CX 128 (USA) alone, high-resolution computed tomography alone |
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Alexandria |
|
Egypt |
2020-05-22 |
2020-06-14 |
IRB (00012098), SN (0304669), NCT04433039 |
Phase Not Applicable |
Completed |
1 |
|
130 |
Ahmed Samir, MD |
2020-06-18 |
| SURG-SAT-19: COVID-19 - Implications on Surgeons' Burnout and Career Satisfaction |
Acute stress disorder, Coronavirus disease 19 infection |
cloud-based software (SurveyMonkey) alone, online survey alone |
|
Healthy volunteers accepted |
Mansoura University |
|
Egypt |
2020-06-15 |
2020-08-31 |
NCT04433286, SURG RES COL 1, SURG-SAT-19 |
Phase Not Applicable |
Not yet recruiting |
1 |
2 Months |
1000 |
Ahmed M Elsheikh, MD,MBA,CMQOE, Hosam Hamed, MD, MSc, PhD, Mostafa Shalaby, MD, MSc, PhD |
2020-06-17 |
| The Development of Pancreatic Injury in the Course of Severe Acute Respiratory Syndrome Coronavirus-2 Infection |
Coronavirus disease 19 infection, Pancreas injury, Viral pneumonia |
biochemical analysis alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Usak University, Turkey |
|
Turkey |
2020-03-01 |
2020-06-12 |
NCT04433754, USAKU-CEVDET2 |
Phase Not Applicable |
Completed |
1 |
3 Months |
500 |
Cevdet Duran |
2020-06-18 |
| Clinical study to evaluate the efficiency of specific antibody against SARS-CoV-2 |
Coronavirus disease 19 infection |
antibody tests alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Yokohama City University |
Japan Agency for Medical Research and Development |
Japan |
2020-06-22 |
|
UMIN000040744 |
Phase Not Applicable |
Recruiting |
1 |
|
5000 |
Mie Tsuchiya, tomoyuki miyazaki |
2020-06-18 |
| Maternal Psychological Implications of Covid-19 Pandemic and Possible Effect on Anesthetic Management |
Coronavirus disease 19 infection |
38-questions questionnaire alone, GAD-7 general anxiety disorder scale alone, PHQ-9 depression scale alone |
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
General and Maternity Hospital of Athens Elena Venizelou |
|
Greece |
2020-05-15 |
2020-12-31 |
MATERNAL COVID 19, NCT04432948 |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
200 |
Georgia Micha, Dr |
2020-06-18 |
| BNP, Serum Troponin and D-dimer as Risk Factors in Patients With COVID-19 |
Coronavirus disease 19 infection |
serum sampling alone |
|
|
Assiut University |
|
Egypt |
2020-07-01 |
2021-09-01 |
CARDIAC MARKERS IN COVID-19, NCT04433026 |
Phase Not Applicable |
Not yet recruiting |
1 |
14 Months |
90 |
Areej Osama Ali Mohammed Saleh, Areej Saleh |
2020-06-18 |
| A clinical study to assess Tempol for the treatment of subjects with COVID-19 |
Coronavirus disease 19 infection |
Tempol (oral, radiotherapy-induced toxicities), Matrix Biomed alone |
Superoxide dismutase modulator |
|
Adamis Pharmaceuticals Corp |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-06-17 |
| Assessment of Mortality Rates in SARS-CoV-2 Infected Populations Treated With Repurposed Medications |
Coronavirus disease 19 infection |
Variable regimens including azithromycin , chloroquine , hydroxychloroquine |
|
|
Tabula Rasa HealthCare Inc |
|
US |
2020-06-15 |
2021-05-31 |
COVID-19_TRHCPRESCRIBEWELLNESS, NCT04432350 |
Phase Not Applicable |
Not yet recruiting |
1 |
11 Months |
50000 |
Pamela Dow, MS, Veronique Michaud, Veronique Michaud, PhD |
2020-06-18 |
| A Phase III trial of COVID-19 vaccine for COVID-19 patients |
Coronavirus disease 19 infection |
COVID-19 vaccine (inactivated, Vero cells/intramuscular), Wuhan Institute of Biological Products/Wuhan Institute of Virology, CAS alone |
|
|
Wuhan Institute of Biological Products Co Ltd |
|
|
|
|
|
Phase 3 Clinical |
Planned |
0 |
|
|
|
2020-06-18 |
| Effect of Opuntia Cactus extract in patients with Covid-19 |
Coronavirus disease 19 infection, Headache, Myalgia |
Cactus Opuntia alone, standard treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Alborz University of Medical Science |
|
Iran |
2020-07-10 |
|
IR.ABZUMS.REC.1399.024, IRCT20200504047298N2 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
48 |
Zeinab Siami |
2020-06-18 |
| Patients Preferences About Rescheduling Colonoscopies Delayed Due to COVID-19: Cross-Sectional Study |
Colon tumor, Coronavirus disease 19 infection |
|
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Massachusetts General Hospital |
|
US |
2020-06-09 |
2021-04-30 |
2020P001579-1, NCT04432870 |
Phase Not Applicable |
Recruiting |
1 |
10 Months |
200 |
Karen Sepucha, PhD |
2020-06-18 |
| COVINOSE: Prospective diagnosis of Covid-19 infection using exhaled breath analysis by electronic nose |
Coronavirus disease 19 infection |
eNose alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Leiden University Medical Center |
|
Netherlands |
2020-04-17 |
2020-12-31 |
COVINOSE, NL8694 |
Phase Not Applicable |
Recruiting |
1 |
8 Months |
200 |
Geert Groeneveld |
2020-06-18 |
| Phase II trial of Rejuveinix for Covid-19 patients |
Coronavirus disease 19 infection |
Rejuveinix alone |
|
|
Reven LLC |
|
|
|
|
|
Phase 2 Clinical |
Planned |
0 |
|
|
|
2020-06-18 |
| Extracorporeal membrane oxygenation in patients with coronavirus disease 2019 |
Coronavirus disease 19 infection |
Extracorporeal membrane oxygenation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Amsterdam UMC |
|
Netherlands |
2020-03-01 |
2020-12-31 |
NL8706 |
Phase Not Applicable |
Recruiting |
1 |
10 Months |
200 |
Alexander Vlaar |
2020-06-18 |
| Quality of life in patients with suspected COVID-19 |
Coronavirus disease 19 infection |
|
|
|
Centre of expertise for chronic organ failure |
|
Netherlands |
2020-06-04 |
2020-12-01 |
NL8705 |
Phase Not Applicable |
Recruiting |
1 |
5 Months |
10000 |
Martijn Spruit |
2020-06-18 |
| A clinical trial of mRNA vaccine (COVID-19), University of Tokyo/Daiichi-Sankyo for the potential treatment of COVID-19 infection |
Coronavirus disease 19 infection |
mRNA vaccine (COVID-19), University of Tokyo/Daiichi-Sankyo alone |
|
|
Daiichi Sankyo Co Ltd |
|
|
2021-03-31 |
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-06-17 |
| A study to assess the effect of PIKfyve inhibitors for the treatment of COVID-19 infection |
Coronavirus disease 19 infection |
PIKfyve inhibitors, Verge Genomics Inc alone |
|
|
Verge Genomics Inc |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-06-17 |
| PPE, COVID-19, HCW |
Coronavirus disease 19 infection |
personal protective equipment alone |
|
|
Universiti Malaysia Sarawak |
|
Malaysia |
2020-05-06 |
2020-09-30 |
54908, NMRR-20-878-54908 |
Phase Not Applicable |
Not yet recruiting |
35 |
4 Months |
|
Haniza Binti Sahdi, Nurul Fatiha binti Zuraidi |
2020-06-17 |
| Effects of patients' vision and emotions on covid-19 |
Coronavirus disease 19 infection, Depression, Vision disorder |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Universiti Kebangsaan Malaysia |
|
Malaysia |
2020-06-15 |
|
54953, NMRR-20-1123-54953 |
Phase Not Applicable |
Status not specified |
2 |
|
|
DR Bannu A/P Jayallan, Dr. Nor Fariza Ngah |
2020-06-17 |
| Personality traits, depression, work stress, frontliners, Covid-19 |
Acute stress disorder, Coronavirus disease 19 infection, Depression |
|
|
|
Tuanku Jaafar Hospital |
|
Malaysia |
2020-06-15 |
2020-12-31 |
54720, NMRR-20-875-54720 |
Phase Not Applicable |
Status not specified |
1 |
6 Months |
|
Hj. Binaw Samad |
2020-06-17 |
| Incidence of ADR |
Coronavirus disease 19 infection |
|
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Sungai Buloh |
|
Malaysia |
2020-06-09 |
|
55048, NMRR-20-1120-55048 |
Phase Not Applicable |
Status not specified |
1 |
|
|
|
2020-06-17 |
| ICRAD: ICRAD |
Coronavirus disease 19 infection, Rheumatoid arthritis |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sarawak General Hospital |
|
Malaysia |
2020-07-01 |
2021-01-01 |
55262, ICRAD, NMRR-20-1116-55262 |
Phase Not Applicable |
Not yet recruiting |
1 |
6 Months |
15 |
Dr Sharifah Aishah bt Wan Mohamad Akba |
2020-06-16 |
| Efficacy of a new COVID-19 treatment |
Coronavirus disease 19 infection |
artesunate alone, artesunate plus vitamin C |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Malagasy government |
An Oasis of Healing in Mesa, The LifeCo, University of Mauritius |
Madagascar |
2020-04-29 |
2020-09-29 |
PACTR202006899597082 |
Phase 2 Clinical |
Not yet recruiting |
0 |
5 Months |
60 |
MIORAMALALA Sedera, RAKOTO Rafanomezantsoa, RAKOTOARIVELO Rivonirina Andry, RAKOTOSAONA Riana, RAKOTOVAO Andriamiadana Luc, RAMANITRAHASIMBOLA David, RAPELANORO RABENJA Fahafahantsoa, RATSIMBASOA Claude Arsene |
2020-06-18 |
| Children with disability during the COVID-19 outbreak |
Coronavirus disease 19 infection |
|
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The University of Hong Kong |
|
Hong Kong |
2020-03-23 |
|
HKUCTR-2872, UW 20-178, protocol v1-20200306 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1356 |
Dr. Wan-yee Winnie Tso, HKUCTR Administrator |
2020-06-17 |
| RoKiCo: Prospective study to evaluate immunity to SARS-CoV2 in mothers with children in child-care facilities |
Coronavirus disease 19 infection |
biological sampling alone, polymerase chain reaction alone |
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Universitätsmedizin Rostock |
|
Germany |
2020-04-23 |
|
A 2020-0090, DRKS00021614, RoKiCo |
Phase Not Applicable |
Recruiting |
1 |
|
400 |
Dagmar Michel-Lubs, Emil C. Reisinger |
2020-06-17 |
| Effects of COVID-19 on lung function and gas exchange |
Coronavirus disease 19 infection, Interstitial lung disease, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Gesellschaft für Tauch- und Überdruckmedizin e.V, University Hospital, Bonn |
Klinik f. Lungenheilkunde und Beatmungsmedizin, Rhein-Maas Klinikum GmbH |
Germany |
2020-06-16 |
|
179/20, DRKS00022082 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
124 |
Ivanna Rühl, Lars Eichhorn |
2020-06-17 |
| PROFLO: Could prone positioning increase lung function for patients with severe COVID-19 infection? |
Coronavirus disease 19 infection, Hypoxia, Respiratory failure, Viral pneumonia |
high flow nasal cannula alone, noninvasive ventilation alone, prone positioning alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Uppsala County Council |
University Hospital of Uppsala |
Sweden |
2020-04-20 |
2021-06-25 |
1, ISRCTN54917435, PROFLO |
Phase Not Applicable |
Not yet recruiting |
2 |
14 Months |
240 |
Dr Rosen |
2020-06-17 |
| Influence of the Covid-19 pandemic on the patient mix in German emergency departments |
Coronavirus disease 19 infection |
|
|
|
BundeswehrKrankenhaus Ulm |
Klinikum WolfsburgZentrale Notfallaufnahme, Otto-von-Guericke-Universität Magdeburg, Universitätsklinik für Unfallchirurgie,AKTIN-Notaufnahmeregister, University Hospital Magdeburg, University Hospital, Aachen |
Germany |
2020-07-01 |
|
160/15, DRKS00022188 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
500000 |
Martin Kulla, Wiebke Schirrmeister |
2020-06-17 |
| Exploratory Study Of the Therapeutic Effect and Safety Of Rectal Ozone therapyin Patients Positive To SARS-CoV 2 With Mild To Moderate Symptoms (COVID-19) |
Coronavirus disease 19 infection |
conventional therapy alone, rectal ozone therapy alone, Variable regimens including Chloroquine , Heberferon , lopinavir + ritonavir , oseltamivir |
Exo-alpha sialidase inhibitor, HIV protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Center for Scientific Research, Cuba |
|
Cuba |
2020-06-08 |
2020-08-23 |
OZO-001, RPCEC00000320 |
Phase Not Applicable |
Not yet recruiting |
1 |
2 Months |
|
Suarez Iznaga, Zamora Rodriguez |
2020-06-18 |
| Efficacy and Safety of Sofosbuvir/Daclatasvir treatment in COVID-19: A randomized, controlled study |
Coronavirus disease 19 infection, Viral pneumonia |
Standard of care therapy alone, Daktavera plus Gratisovir |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
PHARCO CORPORATE |
|
Egypt |
2020-06-20 |
|
DRKS00022203, IRB0000687, U1111-1253-0458 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
90 |
Mostafa Yakoot |
2020-06-17 |
| The role of children in transmission of COVID19 pandemic: Two case series in Malaysia |
Coronavirus disease 19 infection |
|
|
|
Hospital Sungai Buloh |
|
Malaysia |
2020-06-01 |
2020-08-06 |
NMRR-20-1087-55233 |
Phase Not Applicable |
Status not specified |
1 |
2 Months |
|
Dr LIM SOK BEE |
2020-06-16 |
| Approachs and issues on Corona Disaster for EAP |
Coronavirus disease 19 infection |
Psychological education alone |
|
Healthy volunteers accepted |
ADVANTAGE Risk Management Co., Ltd. |
|
Japan |
2020-06-15 |
|
UMIN000040762 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Suzuki Junya |
2020-06-16 |
| Covid19HCW: Prevalence of seroconversion of COVID-19 among healthcare worker |
Coronavirus disease 19 infection |
RT-PCR test alone, seroconversion test kits alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
HOSPITAL QUEEN ELIZABETH II |
|
Malaysia |
2020-05-11 |
2020-07-31 |
Covid19HCW, NMRR-20-885-54906 |
Phase Not Applicable |
Not yet recruiting |
1 |
2 Months |
|
Dr Yen Chia How |
2020-06-18 |
| Children During the COVID-19 Outbreak |
Coronavirus disease 19 infection |
|
|
Preschool Children (2-5 yrs), Children (6-12 yrs) |
The University of Hong Kong |
Community Child Health Unit |
Hong Kong |
2020-03-23 |
|
HKUCTR-2871, UW 20-177, v1-20200305 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1356 |
Dr. Winnie Tso, HKUCTR Administrator |
2020-06-16 |
| Scientific guidance for risk-control and prevention of COVID-19 in professional soccer-players in Austria |
Coronavirus disease 19 infection |
RT-PCR alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Paracelsus Medical University |
|
Austria |
2020-05-18 |
|
415-EP/73/820-2020, DRKS00022166 |
Phase Not Applicable |
Recruiting |
1 |
|
250 |
Dagmar Schaffler |
2020-06-17 |
| A real-time national survey OF COVID-19 in hemoglobinopathy and rare inherited anemia patients |
Anemia, Coronavirus disease 19 infection, Sickle cell anemia, Thalassemia |
|
|
|
Queen Mary University of London |
|
UK |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
|
|
2020-06-16 |
| GI IN COVID-19 |
Coronavirus disease 19 infection |
|
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Queen Elizabeth |
|
Malaysia |
2020-05-18 |
2020-12-31 |
54764, NMRR-20-869-54764 |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
200 |
Dr Ho Yoke Fun |
2020-06-17 |
| Psychosocial experiences among quarantined healthcare workers |
Coronavirus disease 19 infection |
|
|
|
Universiti Malaysia Sarawak |
|
Malaysia |
2020-07-01 |
2020-09-30 |
54833, NMRR-20-1144-54833 |
Phase Not Applicable |
Not yet recruiting |
2 |
3 Months |
|
Prof. Chew Keng Sheng |
2020-06-17 |
| Studying tobacco use and quitting behavior due to the coronavirus lockdown in India |
Coronavirus disease 19 infection |
interviewer-administered telephone-based survey alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
HRIDAY, Public Health Foundation of India |
University of Edinburgh |
India |
2020-06-20 |
|
CTRI/2020/06/025850, HMSC proposal ref id: 2020-9500 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
800 |
Dr Monika Arora, Prof K Srinath Reddy |
2020-06-18 |
| RNB in UPUMS, Saifai |
Coronavirus disease 19 infection |
RNB (Raj Nirvan Bati) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Uttar Pradesh University of Medical Sciences |
|
India |
2020-06-14 |
|
CTRI/2020/06/025852 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
|
|
Dr Raj Kumar |
2020-06-17 |
| Mental Health of children during COVID-19 Pandemic |
Coronavirus disease 19 infection |
|
|
Children (6-12 yrs), Adolescents (13-17 yrs) |
ESI Post Graduate Institute of Medical Science and Research (PGIMSR) |
|
India |
2020-06-17 |
|
CTRI/2020/06/025853 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Jyoti Bagla, Mahima Rajan |
2020-06-17 |
| BCG for COVID-19: BCG Vaccination against COVID-19 |
Coronavirus disease 19 infection, Respiratory disease |
BCG vaccine alone |
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Indian Council of Medical Research |
|
India |
2020-06-25 |
|
BCG for COVID-19, CTRI/2020/06/025854, Version 3.2 |
Phase 4 Clinical |
Not yet recruiting |
6 |
|
1450 |
C Padmapriyadarsini, Dr Anant Mohan, Dr Asha Keetharam, Dr C Padmapriyadarsini, Dr R R Tiwari, Dr Rujuta Hadaye, Dr Toteja, Srikanth Tripathy |
2020-06-17 |
| FLARE: A randomised, double-blind, 2×2 factorial placebo-controlled trial on the saftey and efficacy Favipiravir, lopinavir/ritonavir combination therapy in early antiviral therapy in COVID-19 infection |
Coronavirus disease 19 infection |
favipiravir plus lopinavir + ritonavir |
HIV protease inhibitor, RNA polymerase inhibitor |
|
University of London |
LifeArc |
UK |
|
|
FLARE |
Phase Not Applicable |
Status not specified |
1 |
|
|
|
2020-06-16 |
| Short-term Outcome of COVID-19 Surgical Patients: Case-series of a High-risk Area Community Hospital |
Coronavirus disease 19 infection |
surgical procedure alone |
|
|
Azienda Socio Sanitaria Territoriale di Lodi |
|
Italy |
2020-05-01 |
2020-05-30 |
COVID19NR1, NCT04430062 |
Phase Not Applicable |
Completed |
1 |
|
14 |
Michele Ballabio |
2020-06-17 |
| Clinical Analysis of Patients Hospitalized Due To COVID-19 |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
TNMC and BYL Nair Hospital |
|
India |
2020-06-21 |
|
CTRI/2020/06/025848 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1500 |
Minal Harde, Rakesh Bhadade |
2020-06-17 |
| Study to Evaluate the Safety and Efficacy of a Combination of Nitazoxanide and Hydroxychloroquine Versus Hydroxychloroquine Alone in COVID-19 Patients |
Coronavirus disease 19 infection |
hydroxychloroquine plus nitazoxanide |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Dr Reddy's Laboratories Ltd |
|
India |
2020-06-15 |
|
CTRI/2020/06/025849, CVD-19-CD-001 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
158 |
D Mallikarjuna Rao, Dr Apurva Agarwal |
2020-06-17 |
| Safety, Tolerability and Efficacy of Nangibotide in Mechanically Ventilated Patients With COVID-19 and Features of Systemic Inflammation |
Coronavirus disease 19 infection, Inflammatory disease, Respiratory failure |
nangibotide alone, standard of care alone |
TREM receptor 1 antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Inotrem SA |
|
France |
2020-06-30 |
2021-03-31 |
MOT-C-204, NCT04429334 |
Phase 2 Clinical |
Not yet recruiting |
1 |
9 Months |
60 |
Jean-Jacques Garaud, MD, Sébastien Gibot, MD |
2020-06-17 |
| Pre-Identified Homoeopathic Medicines In Asymptomatic Covid -19 Individuals Receiving Standard Treatment Protocol |
Coronavirus disease 19 infection |
Standard treatment alone, Variable regimens including Arsenicum album 30 , Bryonia 30 , Camphora 1M |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Central Council for Research in Homoeopathy |
|
India |
2020-06-22 |
|
CTRI/2020/06/025844 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
|
Dr Anil Khurana, Dr Varanasi Roja |
2020-06-16 |
| Registry for a Cardiovascular Patient Who COVID-19 Infection |
Acute coronary syndrome, Cardiac arrest, Coronavirus disease 19 infection, Heart arrhythmia, Myocarditis |
transthoracic echocardiography alone, ultrasound alone |
|
|
Hamad Medical Corp |
|
Qatar |
2020-06-02 |
2020-12-31 |
MRC-05-113, NCT04430374 |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
100 |
DR.Jassim Alsuwaidi Senior Consultant, Dr.Jassim Alsuwaidi Senior Consultant, MRC |
2020-06-16 |
| COVIpreg-UK: Studying the immune response and long-term morbidity of COVID-19 infection in pregnancy |
Coronavirus disease 19 infection |
|
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Queen Mary University of London |
February Foundation |
UK |
2020-05-07 |
2022-06-06 |
COVIpreg-UK, IRAS 283699, ISRCTN93266696 |
Phase Not Applicable |
Recruiting |
1 |
25 Months |
200 |
Dr Dodds, Dr Stamatina Iliodromiti |
2020-06-16 |
| A phase III trial of Inactivated vaccine (COVID-19), Sinovac Biotech for COVID-19 |
Coronavirus disease 19 infection |
CoronaVac alone |
|
|
Instituto Butantan, Sinovac Biotech Ltd |
|
Brazil |
|
|
|
Phase 3 Clinical |
Planned |
1 |
|
|
|
2020-06-18 |
| CELMA: Safety and Efficacy of Mesenchymal Stem Cells in the Management of Severe COVID-19 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
Umbilical cord derived mesenchymal stem cells alone, Usual treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Trustem |
Fundación Universitaria de Ciencias de la Salud, Hospital Infantil Universitario de San Jose, Hospital de San Jose |
|
2020-07-31 |
2020-11-30 |
202001, CELMA, NCT04429763 |
Phase 2 Clinical |
Not yet recruiting |
0 |
4 Months |
30 |
Carlos Escobar-Soto, MD, PhD, Carolina Araque, MD, Esp, Guillermo Sánchez-Vanegas, MD, PhD, Jhon Jaime Sprockel Díaz, MD, Esp |
2020-06-16 |
| Safety of TY-027, a Treatment for COVID-19, in Humans |
Coronavirus disease 19 infection |
TY-027, Tychan alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Tychan Pte Ltd |
|
Singapore |
2020-06-09 |
2021-01-31 |
NCT04429529, SCT-001 |
Phase 1 Clinical |
Recruiting |
1 |
7 Months |
25 |
Anjali Baglody, MSc, Bo Hong Tay, Jenny Low, MBBS, Justin Ng, PhD, Shayne Lin |
2020-06-17 |
| LCECS: Development and Application of a Low-Cost Ear-Contactless Stethoscope Powered by Raspberry Pi and Python |
Coronavirus disease 19 infection |
Low-Cost Ear-Contactless Stethoscope alone |
|
Healthy volunteers accepted |
Shengjing Hospital of China Medical University |
|
China |
2020-06-12 |
2021-06-12 |
ChiCTR2000033830, LCECS |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
12 |
Chuan Yang |
2020-06-17 |
| A phase III clinical study of SARS-CoV-2 vaccine, Ad26.COV2-S for the treatment of COVID-19 |
Coronavirus disease 19 infection |
SARS-CoV-2 recombinant adenoviral vector vaccine (AdVac/PER.C6, COVID-19), Johnson & Johnson/Biomedical Advanced Research and Development Authority/Beth Israel Deaconess Medical Center alone |
|
|
Johnson & Johnson |
|
|
|
|
|
Phase 3 Clinical |
Planned |
0 |
|
|
|
2020-06-15 |
| COMETE-19: Covid-19 at the Regional Medical Center Metz-Thionville: a Descriptive Study |
Coronavirus disease 19 infection |
|
|
|
Centre Hospitalier Régional Metz-Thionville |
|
France |
2020-03-01 |
2021-06-30 |
2020-02OBS-CHRMT, COMETE-19, NCT04430322 |
Phase Not Applicable |
Recruiting |
1 |
16 Months |
330 |
Nadia OUAMARA, Rostane GACI, MD, Vincent DINOT |
2020-06-15 |
| Hydroxychloroquine Use in Hospitalized Patients With COVID-19: Impact on Progression to Severe or Critical Disease |
Coronavirus disease 19 infection |
hydroxychloroquine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
WellStar Health System |
|
US |
2020-05-07 |
2020-12-07 |
1604885, NCT04429867 |
Phase 4 Clinical |
No longer recruiting |
1 |
7 Months |
700 |
|
2020-06-18 |
| OpMiCoV: Explorative Study of the Association of Oropharyngeal Microbiota Profiles with SARS-CoV-2 Infection and COVID-19 disease |
Coronavirus disease 19 infection, Upper respiratory tract infection, Viral pneumonia |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Deutsches Krebsforschungszentrum |
|
Germany |
2020-04-02 |
|
DRKS00021424, OpMiCoV, S-194/2020, U1111-1253-4873 |
Phase Not Applicable |
No longer recruiting |
1 |
|
360 |
Christoph Stein-Thoeringer |
2020-06-17 |
| Epidemiological and Demographic Data From 150 Patients Diagnosed With Coronavirus Disease 2019 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sisli Etfal Hospital |
|
Turkey |
2020-05-15 |
2020-06-05 |
DM3334, NCT04430023 |
Phase Not Applicable |
Completed |
1 |
|
150 |
AYŞE SÜRHAN ÇINAR, ayse cinar |
2020-06-18 |
| Health Professional Exposure Assessment to Covid-19 (SERODRON) |
Coronavirus disease 19 infection |
RT-PCR test alone, blood sampling alone, serological test alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier de Tourcoing |
|
France |
2020-06-30 |
2020-12-31 |
NCT04429724, RIPH_2020_8 |
Phase Not Applicable |
Not yet recruiting |
3 |
6 Months |
6000 |
Pierre PATOZ, PharmD, SIVERY, Solange TREHOUX, PhD, VACHEE |
2020-06-17 |
| MAGIC: Impact of Smoking and Nicotine on the Risk of Being Infected With COVID-19 |
Coronavirus disease 19 infection, Nicotine dependence |
nicotine substitute therapy alone, serological test alone, smoking cessation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Central Hospital, Nancy, France |
|
France |
2020-07-01 |
2021-04-01 |
2020-A01681-38, MAGIC, NCT04429815 |
Phase Not Applicable |
Not yet recruiting |
1 |
9 Months |
489 |
Christian Rabaud |
2020-06-16 |
| A study to predict the disease progression in COVID-19 patients by analyzing blood samples of these patients from using high-throughput mass spectrometry platform |
Coronavirus disease 19 infection |
high-throughput mass spectrometry alone |
|
|
Charite Universitaetsmedizin Berlin |
The Francis Crick Institute |
UK |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
31 |
Prof. Dr. Markus Ralser |
2020-06-15 |
| A phase I clinical study to assess TP-508 in the treatment of patients with COVID-19 |
Coronavirus disease 19 infection |
rusalatide alone |
Factor IIa modulator |
|
Chrysalis BioTechnology Inc |
National Institute of Allergy and Infectious Diseases |
|
|
|
|
Phase 1 Clinical |
Planned |
0 |
|
|
|
2020-06-15 |
| Follow-up of COVID-19 Positive Patients |
Coronavirus disease 19 infection |
|
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Bangladesh Health Professions Institute |
|
Bangladesh |
2020-06-23 |
|
CTRI/2020/06/025857 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
200 |
K M Amran Hossain, Md. Obaidul Haque |
2020-06-16 |
| SARS-CoV2 IIF: Prospective Assay for SARS-CoV-2 Antibody Detection Indirectly by Immunofluorescence |
Coronavirus disease 19 infection |
SARS-CoV2 ELISA alone, immunofluorescence (SARS-CoV2 IIF ) alone, qPCR assay alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Szeged |
Biological Research Center of the Hungarian Academy of Sciences |
Hungary |
2020-05-30 |
2020-12-31 |
NCT04429620, SARS-COV-2-IIF-002, SARS-CoV2 IIF |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
100 |
Dávid Pintér, Pharm. D., Katalin Burián, MD |
2020-06-16 |
| A phase II clinical study to assess TP-508 in the treatment of patients with COVID-19 |
Coronavirus disease 19 infection |
rusalatide alone |
Factor IIa modulator |
|
Chrysalis BioTechnology Inc, National Institute of Allergy and Infectious Diseases |
|
|
|
|
|
Phase 2 Clinical |
Planned |
0 |
|
|
|
2020-06-15 |
| Evaluation of siddha regimen in the management of covid 19 |
Coronavirus disease 19 infection |
Variable regimens including Adathodai Manapagu , Kabasura kudineer , Thippili Rasayanam , Vasantha kusumakaram Mathirai |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Government Siddha Medical College |
|
India |
2020-06-25 |
|
CTRI/2020/06/025856 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
|
Dr N Anbu, Dr S M Chitra |
2020-06-16 |
| A retrospective, cohort, uncontrolled, exploratory study to evaluate the effects of treatment with interferon-alpha2b in the confirmed COVID-19 patients in Wuhan, China |
Coronavirus disease 19 infection |
interferon alpha-2b (COVID-19, inhaled), Altum Pharmaceuticals alone, arbidol plus interferon alpha-2b (COVID-19, inhaled), Altum Pharmaceuticals |
Interferon alpha ligand modulator |
|
Union Hospital Tongji Medical School Huazhong University Of Science & Technology |
|
China |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
77 |
|
2020-06-15 |
| Effect of AYUSH 64 in COVID 19 |
Coronavirus disease 19 infection |
AYUSH 64 alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Institute for Post Graduate Teaching and Research in Ayurveda |
|
India |
2020-06-15 |
|
CTRI/2020/06/025855 |
Phase 2 Clinical |
Not yet recruiting |
2 |
|
200 |
Dr Mandip Goyal, Dr Sagar M Bhinde, Dr Yagnik Chotala, Prof Anup Thakar |
2020-06-15 |
| SPIKE-1: A Randomized, Phase II/III trial to assess the use of camostat in reducing the clinical progression of COVID-19 by blocking SARS-CoV-2 Spike protein-initiated membrane fusion |
Coronavirus disease 19 infection |
camostat mesylate alone |
Serine protease inhibitor, Transmembrane serine protease 2 inhibitor, Trypsin inhibitor |
|
University of Edinburgh |
LifeArc |
UK |
|
|
SPIKE-1 |
Phase 2/Phase 3 Clinical |
Status not specified |
1 |
|
|
|
2020-06-16 |
| Serum protein marker in patients with novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Healthy volunteers accepted, Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Chongqing People'S Hospital |
|
China |
2020-02-01 |
2022-02-01 |
ChiCTR2000033872 |
Phase 0 Clinical |
No longer recruiting |
1 |
24 Months |
350 |
Ling Yan, Pu Liao |
2020-06-16 |
| Efficacy, Safety, Tolerability, and Biomarkers of MN-166 (Ibudilast) in Patients Hospitalized With COVID-19 and at Risk for ARDS |
Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia |
ibudilast (oral, neuropathic pain/opiate dependence/neurodegeneration/TBI/drug dependence/acute respiratory distress syndrome/COVID-19), MediciNova alone |
IL-6 receptor antagonist, Interleukin-1 beta ligand inhibitor, Macrophage migration inhibitory factor inhibitor, PDE 10 inhibitor, PDE 4 inhibitor, TLR-4 antagonist, TNF alpha ligand inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
MediciNova Inc, Yale School of Medicine |
|
US |
2020-07-31 |
2021-12-01 |
MN-166-COVID-19-201, NCT04429555 |
Phase 2 Clinical |
Not yet recruiting |
1 |
16 Months |
40 |
Dr. Geoffrey Chupp, Dr. Insoo Kang, Joanna Dojillo, MMsc, Kazuko Matsuda, MD PhD MPH, r. Maor Sauler |
2020-06-16 |
| A pilot study of baricitinib for treatment of bilateral COVID-19 pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
baricitinib alone |
Jak1 tyrosine kinase inhibitor, Jak2 tyrosine kinase inhibitor |
|
Eli Lilly & Co, Imperial College London |
|
Italy |
|
|
|
Phase 2 Clinical |
Status not specified |
1 |
|
4 |
|
2020-06-15 |
| The efficacy and safety of convalescent plasma therapy in novel coronavirus pneumonia (COVID-19): A medical records based retrospective, cohort study |
Coronavirus disease 19 infection, Viral pneumonia |
convalescent plasma therap alone, non-convalescent plasma therapy alone |
|
Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tongji Hospital, Huazhong University of Science and Technology |
|
China |
2020-06-12 |
2021-06-11 |
ChiCTR2000033798 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
150 |
Minghao Fang, Yi Bian |
2020-06-16 |
| Cerebral Compliance Impairment in COVID-19 |
Brain disease, Coronavirus disease 19 infection |
Brain4care (B4C) sensor alone, Transcranial Doppler alone |
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Sao Paulo |
|
Brazil |
2020-05-01 |
2020-07-31 |
31750820.1.0000.0068, NCT04429477 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
50 |
Gustavo Frigieri, PhD, Sergio Brasil, MD, Sergio Brasil, PhD |
2020-06-16 |
| DAWN-Plasma: Donated Antibodies Working Against nCoV |
Coronavirus disease 19 infection, Lower respiratory tract infection, Upper respiratory tract inflammation |
Convalescent plasma alone, Standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universitaire Ziekenhuizen Leuven |
Federal Knowledge Centre (KCE) |
Belgium |
2020-05-02 |
2021-11-02 |
DAWN-Plasma, NCT04429854, S63992 |
Phase 2 Clinical |
Recruiting |
14 |
18 Months |
483 |
Bernard Bouckaert, MD, Clotilde Visée, MD, Geert Meyfroidt, MD, PhD, Georgala Aspasia, MD, Jean Yombi, MD, Laurent Jadot, MD, Lucie Seyler, MD, Matthias Leys, MD, Michel Moutschen, MD, Nicolas Dauby, MD, Niels Van Regenmortel, MD, Timothy Devos, MD,PHD |
2020-06-16 |
| A phase II clinical study of self-amplifying RNA vaccine (im, COVID-19), Imperial College London for the potential prevention of SARS-CoV-2 infection (COVID-19) |
Coronavirus disease 19 infection |
self-amplifying RNA vaccine (im, COVID-19), Imperial College London alone |
COVID19 Spike glycoprotein inhibitor |
|
Imperial College London |
UK Government |
|
2020-06-30 |
|
|
Phase 2 Clinical |
Planned |
0 |
|
|
|
2020-06-15 |
| CGM-ISO: Remote Continues Glucose Monitoring During the COVID-19 Pandemic in Quarantined Hospitalized Patients |
Coronavirus disease 19 infection, Diabetes mellitus, Viral pneumonia |
CGM stratification alone, Dexcom G6 alone, Standard care with fingerprick glucose test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Nordsjaellands Hospital |
|
Denmark |
2020-05-25 |
2021-05-25 |
CGM-ISO, H-20025305, NCT04430608 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
72 |
Carina Klarskov, MD, Peter L. Kristensen, MD, ph.D |
2020-06-16 |
| HAD-Covid: Impact of Covid-19 Restrictive Measure on Anxiety, Depression and PTSD for Relatives of ICU Patients |
Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Clermont-Ferrand |
|
France |
2020-06-22 |
2022-01-22 |
2020 HAD-COVID, HAD-Covid, NCT04430049 |
Phase Not Applicable |
Not yet recruiting |
11 |
19 Months |
120 |
Alexandre Lautrette, MD, PhD, Anne Médard, MD, Arnaud Delahaye, MD, Christophe Leroy, MD, Edouard Soum, MD, Emmanuel Futier, MD,PhD, Jean-Etienne Bazin, MD, PhD, Lise Laclautre, Luc Jarrige, MD, Marie-Hélène Hausermann, MD, Nathanael Einsemann, Pierre-Marie Bertrand, MD, Ramin Ravan, MD, Russel Chabanne, MD, Sophie Cayot, MD, Thierry Gillard, MD |
2020-06-16 |
| COV003: A phase III study to investigate a vaccine against COVID-19 |
Coronavirus disease 19 infection |
AZD-1222 alone, AZD-1222 plus paracetamol |
COVID19 Spike glycoprotein modulator |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Federal University of Sao Paulo, University of Oxford |
The Lemann Foundation |
Brazil |
2020-05-01 |
2021-07-31 |
COV003, COV003, ISRCTN89951424 |
Phase 3 Clinical |
Recruiting |
1 |
15 Months |
2000 |
Dr Peter O'Reilly |
2020-06-16 |
| CATALYST: An adaptive, rapid, open-label, phase II, multi-arm, multi-stage clinical trial to evaluate the efficacy of IZN-101 and CT-P13 in the treatment of hospitalized patients with severe COVID-19 infection |
Coronavirus disease 19 infection |
infliximab biosimilar, Celltrion/Nippon Kayaku/Hospira/Orion/EGIS Gyogyszergyar alone, namilumab alone, standard of care alone |
GM-CSF ligand inhibitor, TNF alpha ligand inhibitor, TNF binding agent |
|
NIHR Birmingham Biomedical Research Centre, The University of Birmingham, University Hospital Birmingham NHS Foundation Trust |
NIHR Biomedical Research Centre, Oxford, United Kingdom Research & Innovation, University College London, University of Oxford |
UK, US |
|
|
CATALYST |
Phase 2 Clinical |
Recruiting |
2 |
|
160 |
Dr Ben Fisher, Dr Matt Rowland, Professor Duncan Richards |
2020-06-17 |
| A placebo-controlled trial to evaluate REGN-CoV2 for the prevention of COVID-19 in uninfected people with close exposure to a COVID-19 patient |
Coronavirus disease 19 infection |
REGN-CoV2 alone |
COVID19 Spike glycoprotein inhibitor |
|
Regeneron Pharmaceuticals Inc |
|
US |
2020-06-11 |
|
|
Phase Not Applicable |
Recruiting |
1 |
|
|
Dr. Suraj Saggar |
2020-06-16 |
| A placebo-controlled trial to evaluate REGN-CoV2 for the prevention of COVID-19 in uninfected people who are at high-risk of exposure |
Coronavirus disease 19 infection |
REGN-CoV2 alone |
COVID19 Spike glycoprotein inhibitor |
|
Regeneron Pharmaceuticals Inc |
|
US |
2020-06-11 |
|
|
Phase Not Applicable |
Recruiting |
1 |
|
|
Dr. Suraj Saggar |
2020-06-16 |
| ERNA: An intensive, longitudinal study on habit formation of hand washing behavior during the COVID-19 pandemic |
Coronavirus disease 19 infection |
hand washing alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Medical School Berlin |
Berlin Free University |
Germany |
2020-06-25 |
|
DRKS00022067, ERNA, MSB-2020/36 |
Phase Not Applicable |
Not yet recruiting |
5 |
|
134 |
Antonia Domke, Lena Fleig |
2020-06-15 |
| Ivermectin versus Placebo for the Treatment of Patients With Mild to Moderate COVID-19 |
Coronavirus disease 19 infection |
ivermectin alone |
Chloride channel modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sheba Medical Center |
|
Israel |
2020-05-12 |
2020-10-31 |
NCT04429711, SHEBA-20-7156-ES-CTIL |
Phase 2 Clinical |
Recruiting |
1 |
5 Months |
100 |
Asaf Biber, Dr., Eli Schwartz, M.D, Eli Schwartz, Prof., Prof. Eli Schwartz MD, DTMH |
2020-06-17 |
| A clincial study to assess immune response of QuadraMune in healthy subjects for the prevention of COVID-19 |
Coronavirus disease 19 infection |
QuadraMune alone |
|
Healthy volunteers accepted |
Therapeutics Solutions International Inc |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
8 |
Dr. James Veltmeyer |
2020-06-15 |
| Multicenter, adaptive, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of the drug ХС-221, 100 mg tablets, in patients with COVID-19 |
Coronavirus disease 19 infection |
XC-221 alone |
|
|
RSV Therapeutics LLC |
|
Russian Federation |
2020-06-09 |
2021-12-31 |
ХС221-03-02-2020 |
Phase 3 Clinical |
Status not specified |
7 |
18 Months |
150 |
|
2020-06-15 |
| Post-traumatic Stress Disease in Health Workers During COVID-19 Pandemia |
Coronavirus disease 19 infection, Post traumatic stress disorder |
Maslach Burnout Inventory (MBI) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
IRCCS AOU San Martino – IST |
|
Italy |
2020-03-01 |
2020-07-01 |
NCT04424771, PTSD-COVID-19 |
Phase Not Applicable |
Recruiting |
2 |
4 Months |
800 |
Eleonora Giuntoli, MD, Eleonora Guaitoli, Eleonora Guaitoli, MD, Fabio Barra, Fabio Barra, MD |
2020-06-15 |
| AKI C19 HKL: Acute kidney injury and renal replacement therapy: incidence and outcome in COVID-19 patients admitted to Hospital Kuala Lumpur |
Coronavirus disease 19 infection, Renal injury |
renal replacement therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Kuala Lumpur |
|
Malaysia |
2020-06-15 |
2021-12-31 |
55036, AKI C19 HKL, AKI C19 HKL, NMRR-20-1090-55036 |
Phase Not Applicable |
Not yet recruiting |
1 |
18 Months |
371 |
Dr NURUL ZAYNAH BINTI NORDIN |
2020-06-15 |
| BLAZE-1: A Study of LY-3819253 (LY-CoV555) in Participants With Early Mild-to-Moderate COVID-19 Illness |
Coronavirus disease 19 infection |
LY-CoV555 alone |
COVID19 Spike glycoprotein modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Eli Lilly & Co |
AbCellera Biologics Inc |
US |
2020-06-13 |
2020-09-15 |
17947, BLAZE-1, J2W-MC-PYAB, NCT04427501 |
Phase 2 Clinical |
Recruiting |
23 |
3 Months |
400 |
A Blomkalns, Adam Schwartz, Andra Blomkalns, Carlos Malvestutto, DONALD PORETZ, David Pitrak, Erica Kaufman West, GERARD J CRINER, Gregory Huhn, Imad J Shawa, Jeffrey Glassberg, Katherine Belden, Kristin Highland, Mayur Ramesh, Michael L Dougan, Patrick Milligan, Peter Chen, Princy Kumar, Robert Gottlieb, V Stosor, Valentina Stosor, William A Fischer |
2020-06-18 |
| IDEA: Ivermectin, Aspirin, Dexametasone and Enoxaparin as Treatment of COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
Variable regimens including aspirin , dexamethasone , enoxaparin sodium , ivermectin |
Chloride channel modulator, Low molecular weight heparin |
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Eurnekian Public Hospital |
|
Argentina |
2020-05-01 |
2020-07-30 |
IDEA, IDEA, NCT04425863 |
Phase Not Applicable |
No longer recruiting |
1 |
2 Months |
10 |
Alfredo Secchi, M.D., Hector E Carvallo |
2020-06-18 |
| To Compare Videolaryngoscope Against Direct Laryngoscope for Intubation When Powered Air Purifying Respirator is Worn |
Anesthesia, Coronavirus disease 19 infection |
McGrath videolaryngoscope alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Singapore General Hospital Pte Ltd |
Duke-NUS Graduate Medical School |
Singapore |
2020-06-01 |
2020-12-31 |
2020/2329, NCT04424953 |
Phase Not Applicable |
Not yet recruiting |
1 |
7 Months |
60 |
Qing Yuan Goh, M.Med (Anes), Zihui Tan, M.Med (Anes) |
2020-06-16 |
| Efficacy of Convalescent Plasma Therapy in Patients With COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
Convalescent Plasma therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Institute of Liver and Biliary Sciences, India |
|
India |
2020-06-09 |
2021-05-30 |
ILBS-COVID-04, NCT04425915 |
Phase 3 Clinical |
Recruiting |
3 |
11 Months |
400 |
Dr Ankit Bhardwaj, Masters-CT, Dr Meenu Bajpai, MD, Dr Suresh Kumar, MD, Dr Vikas Dogra, MD |
2020-06-15 |
| Thorax Computed Tomography Severity Score and Outcome in COVID-19 Patients |
Coronavirus disease 19 infection, Viral pneumonia |
CT scan alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tepecik Training and Research Hospital |
|
Turkey |
2020-03-15 |
2020-07-15 |
2020/5-4, NCT04424849 |
Phase Not Applicable |
Recruiting |
1 |
4 Months |
40 |
Aykut Sarıtaş, Isıl K Guldogan, Işıl Köse Güldoğan, Kazim Rollas, Kazım Rollas, Naciye Sinem GEZER, Nimet Şenoğlu, Taner Çalışkan, Uğur Uzun, Yeliz Pekçevik, Çiler Zincircioğlu, İsa Sahar |
2020-06-15 |
| Cardiovascular Risk Factors and Severe COVID-19. A Nationwide, Registry-based, Case-control Study |
Cardiovascular disease, Coronavirus disease 19 infection, Hypertension, Non-insulin dependent diabetes, Obesity |
antidiabetic therapy alone, antihypertensive agent therapy alone, statin therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Karolinska Institutet |
|
Sweden |
2020-03-01 |
2022-12-31 |
4, NCT04426084 |
Phase Not Applicable |
No longer recruiting |
1 |
34 Months |
22784 |
Per Svensson |
2020-06-15 |
| AiM Covid Self Monitoring |
Coronavirus disease 19 infection |
AiM Covid App alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Aarogyam UK |
Mothers Touch Foundation, NMP Medical Research Institute, Warwick University |
India |
2020-04-12 |
2020-05-28 |
AU015, NCT04425044 |
Phase Not Applicable |
Completed |
2 |
1 Month |
1000 |
Vishwes Kulkarni |
2020-06-15 |
| Thymosin Alpha 1 to Prevent COVID-19 Infection in Elderly Renal Dialysis Patients |
Coronavirus disease 19 infection |
thymalfasin alone |
Thymosin receptor agonist |
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Inova Health Care Services |
DaVita Clinical Research, Nephrology Associates of Northern Virginia, Inc. |
US |
2020-06-30 |
2021-06-30 |
ACW-1221958-1, NCT04428008 |
Phase 2 Clinical |
Not yet recruiting |
1 |
12 Months |
240 |
William B Ershler, MD, William B. Ershler |
2020-06-18 |
| A Multicenter, Randomized, Double-blind, Placebo-controlled, Phase III Study Evaluating Favipiravir in Treatment of COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
favipiravir alone, supportive care alone |
RNA polymerase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Zhejiang Hisun Pharmaceutical Co Ltd |
Opera CRO |
China, Germany, Romania |
2020-06-30 |
2020-09-30 |
HS216C17(MRCT), NCT04425460 |
Phase 3 Clinical |
Not yet recruiting |
8 |
3 Months |
256 |
Dionisio Barattini, MD Europe, Opera CRO, Emanuel Dogaru, CPM, Opera CRO |
2020-06-16 |
| COVID-19 ORL: Smell and Taste Disorders in COVID-19 Patients |
Coronavirus disease 19 infection, Taste disorder |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Milano-Bicocca |
|
Italy |
2020-05-15 |
2020-09-30 |
COVID-19 ORL, COVID-19 ORL, NCT04427332 |
Phase Not Applicable |
Recruiting |
1 |
4 Months |
500 |
Dante Jean Garavello Werner Jean, Prof., Dante Jean Garavello Werner, Professor |
2020-06-16 |
| COVID_OFF: Detection of SARS-CoV-2 in Follicular Fluid and Cumulus-oocyte-complexes in COVID-19 Patients |
Coronavirus disease 19 infection |
Endometrial biopsy alone |
|
Female, Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
CRG UZ Brussel |
|
Belgium |
2020-06-15 |
2021-06-15 |
COVIDOFF001, COVID_OFF, NCT04425317 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
20 |
Elsie Nulens, Liese Boudry, Liese Boudry, MD |
2020-06-16 |
| Masq-Aute: Evaluation of ARFC Masks Equipped With CF5 Filter in the Care Unit to Allow a Wider Distribution of FFP2 Masks (Covid-19) |
Coronavirus disease 19 infection |
ARFC mask alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire de Saint Etienne |
|
France |
2020-04-29 |
2020-06-30 |
2020-A00817-32, 20CH073, Masq-Aute, NCT04427176 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
30 |
Andréa BUCHMULLER, MD, Bernard TARDY, MD PhD, Florence RANCON, CRA, Jean Luc PERROT, MD PhD, Jean-Luc PERROT, MD PhD |
2020-06-15 |
| TOLD: Trial of Open-Label Dipyridamole In Hospitalized Patients With COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure, Respiratory tract infection |
dipyridamole alone, standard care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
UConn Health |
|
US |
2020-05-03 |
2021-05-30 |
20-192-2.F, NCT04424901, TOLD |
Phase 2 Clinical |
Recruiting |
1 |
12 Months |
100 |
Bruce Liang, MD, Christopher Pickett, MD, Elizabeth Laska, RN, Eric Mortensen, MD, Jeffrey Aeschlimann, PharmD, Kevin Dieckhaus, MD, Mark Metersky, MD, Patti Keltonic, RN |
2020-06-15 |
| A phase Ia/Ib clinical trial of trans sodium crocetinate for the treatment of hospitalized COVID-19 patients displaying severe respiratory symptoms and low oxygen levels |
Coronavirus disease 19 infection |
trans sodium crocetinate alone |
|
|
ARENSIA Exploratory Medicine, Diffusion Pharmaceuticals LLC |
|
Romania |
2020-06-30 |
|
|
Phase 1 Clinical |
Planned |
1 |
|
|
Prof. Adrian Streinu-Cercel |
2020-06-12 |
| Vitamin A and COVID-19 |
Coronavirus disease 19 infection |
vitamin A alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Iran University of Medical Sciences |
|
Iran |
2020-05-21 |
|
IR.IUMS.REC.1399.204, IRCT20200405046951N1 |
Phase 3 Clinical |
Recruiting |
1 |
|
120 |
Azadeh Mottaghi |
2020-06-15 |
| Evaluation the effect of raltegravir and raltegravir/interferon beta combination on COVID-19 patients |
Coronavirus disease 19 infection |
Variable regimens including hydroxychloroquine , interferon beta , raltegravir |
HIV-1 integrase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Jahrom University of Medical |
|
Iran |
2020-06-19 |
|
IR.JUMS.REC.1399.028, IRCT20200412047042N1 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
60 |
Dr Kavous Solhjoo, Dr Rahim Raoufi, ِDr Samaneh Zolghadri |
2020-06-17 |
| Assessment of Thermal Condition of Health Workers Who Use Personal Protective Equipment From Biological Hazards During Their Work With COVID-19 Patients |
Coronavirus disease 19 infection |
Personal protective equipment alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Federal State Budgetary Scientific Institution 'Izmerov Research Institute of Occupational Health' |
|
Russian Federation |
2020-06-03 |
2020-06-10 |
NCT04427267, PPE-02 |
Phase Not Applicable |
No longer recruiting |
1 |
|
6 |
Andrey Mikhailovich Geregey |
2020-06-17 |
| VENTED COVID: Low Dose Whole Lung Radiation Therapy for Patients With COVID-19 and Respiratory Compromise |
Coronavirus disease 19 infection, Hypoxia, Lung inflammation, Respiratory disease, Viral pneumonia |
ultralow dose-whole lung radiation therapy (80 cGy) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ohio State University Comprehensive Cancer Center |
|
US |
2020-06-30 |
2021-12-31 |
NCT04427566, VENTED, VENTED COVID |
Phase 2 Clinical |
Not yet recruiting |
1 |
18 Months |
24 |
Arnab Chakravarti, Kimberly Mahler |
2020-06-17 |
| VExCO: Mechanical ventilator for use in patients with respiratory failure due to Covid-19 |
Coronavirus disease 19 infection, Respiratory failure |
ventilator alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Hospital Universitario Clementino Fraga Filho, Universidade Federal do Rio de Janeiro |
Foundation for Research Financial Support in the State of Rio de Janeiro (FAPERJ) |
Brazil |
2020-06-04 |
2020-06-11 |
4.063.224, CAAE: 31031920.2.0000.5257, RBR-2dxyx4, U1111-1252-8144, VExCO |
Phase Not Applicable |
Not yet recruiting |
1 |
|
5 |
Diamantino Ribeiro Salgado |
2020-06-16 |
| HFNC Treatment in COVID-19 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
high flow nasal cannula device alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sisli Hamidiye Etfal Training and Research Hospital |
|
Turkey |
2020-05-15 |
2020-06-05 |
5569, NCT04424836 |
Phase Not Applicable |
Recruiting |
1 |
|
40 |
ayse su cinar, mustafa altinay, mustafa altınay, nebia peker |
2020-06-17 |
| Therapeutic Vaccine Trial of COVID-19 for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection |
Coronavirus disease 19 infection |
Covax-19 alone |
Coronavirus spike glycoprotein inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Genecure LLC, Vaxine Pty Ltd |
|
|
2020-07-31 |
2021-12-31 |
GC004, NCT04428073 |
Phase 1 Clinical |
Not yet recruiting |
0 |
17 Months |
32 |
Frank Tung, Ph.D |
2020-06-18 |
| Identification of Genetic Factors Determining Disease Course in the New Type of Coronavirus Infection, COVID-19 |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Szeged |
|
Hungary |
2020-06-05 |
2021-07-31 |
COVID19_HUNGEN_001, NCT04426253 |
Phase Not Applicable |
No longer recruiting |
11 |
13 Months |
1000 |
Márta Széll, MD, Ph.D. |
2020-06-15 |
| Chloroquine + Losartan Compared to Chloroquine Alone for the Treatment of COVID-19 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
chloroquine phosphate plus losartan |
Angiotensin II AT-1 receptor antagonist, Angiotensin II receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Universitario Dr. Jose E. Gonzalez |
|
Mexico |
2020-03-10 |
2020-08-30 |
IF20-00003, NCT04428268 |
Phase 2 Clinical |
Recruiting |
1 |
5 Months |
20 |
Adrian Camacho Ortiz, MD, Adrian Camacho, PhD, Adrian Camacho-Ortiz, PhD, Eduardo Pérez Alba, MD, Juan Diego Lecona García, MD, Laura Marina Nuzzolo Shihadeh, MD |
2020-06-17 |
| Autologous Adipose-derived Stem Cells (AdMSCs) for COVID-19 |
Coronavirus disease 19 infection |
AdMSCs (osteoarthritis/rheumatoid arthritis), CelltexTherapeutics alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Celltex Therapeutics Corp |
|
US |
2020-06-20 |
2021-08-10 |
CTX0020-003, NCT04428801 |
Phase 2 Clinical |
Not yet recruiting |
1 |
13 Months |
200 |
Candy Eller, Derek W Guillory, MD. |
2020-06-17 |
| SERO-MARES: Prevalence and Risk Factors of SARS-CoV-2 Antibody Responses (COVID-19) |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital de Mataró |
|
Spain |
2020-06-08 |
2021-06-30 |
NCT04425759, SERO-MARES, SERO-MARES (56/20) |
Phase Not Applicable |
Recruiting |
2 |
12 Months |
2400 |
Pere Clavé, MD, Pere Clavé, MD, PhD |
2020-06-17 |
| IVERCAR: Usefulness of Topic Ivermectin and Carrageenan to Prevent Contagion of Covid 19 |
Coronavirus disease 19 infection |
personal protective equipment usage alone, Ivercass (ivermectin) plus iota carrageenan (Nasitral) |
|
Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Eurnekian Public Hospital |
|
Argentina |
2020-06-01 |
2020-08-30 |
IVERCAR, IVERCAR, NCT04425850 |
Phase Not Applicable |
No longer recruiting |
1 |
2 Months |
70 |
Hector E Carvallo |
2020-06-18 |
| BIG-C: Exploring Interventions for Glue Ear During Covid-19 |
Coronavirus disease 19 infection, Hearing loss, Otitis media |
Hear Glue Ear app (Cambridgeshire Community Services NHS Trust) alone, bone conduction headphone alone, microphone alone, telephone consultation alone, video consultation alone |
|
Preschool Children (2-5 yrs), Children (6-12 yrs) |
Cambridgeshire Community Services NHS Trust |
Cambridge University Hospitals NHS Foundation Trust |
UK |
2020-06-22 |
2021-06-01 |
262816, BIG-C, NCT04427631 |
Phase Not Applicable |
Not yet recruiting |
1 |
11 Months |
20 |
Alison Sansome, BM BCh MA MRCPCH, Dr. Tamsin Brown, Tamsin M Holland Brown, MBBS MRCPCH, alison Sansome, MBBS MRCPCH |
2020-06-15 |
| The efficacy of barely-based traditional remedy on COVID-19 |
Coronavirus disease 19 infection |
Variable regimens including atazanavir + ritonavir , barley-based remedy , chloroquine phosphate , hydroxychloroquine , lopinavir + ritonavir |
HIV protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shahid Beheshti University |
|
Iran |
2020-05-13 |
|
IR.SBMU.RETECH.REC.1399.074, IRCT20180923041093N6 |
Phase 3 Clinical |
No longer recruiting |
1 |
|
60 |
Mahmood Khodadoost, Roshanak Mokaberinejad |
2020-06-18 |
| COV-OB-ICU: Obesity and Mortality of Critically Ill Patients With COVID-19 |
Coronavirus disease 19 infection, Obesity, Respiratory failure, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Central Hospital, Nancy, France |
|
France |
2020-05-12 |
2020-05-26 |
2020PI082, COV-OB-ICU, NCT04425213 |
Phase Not Applicable |
Completed |
1 |
|
250 |
Olivier Ziegler, PU-PH |
2020-06-17 |
| Use of Remote Monitoring for COVID-19 Patient |
Coronavirus disease 19 infection |
LifeSignals Biosensor 1AX alone, Remote Patient Monitoring alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Montefiore Medical Center |
|
US |
2020-06-05 |
2021-06-01 |
NCT04425720, PENDING |
Phase Not Applicable |
Not yet recruiting |
1 |
11 Months |
300 |
Jonathan Leff, MD, Singh Nair, PhD |
2020-06-16 |
| Early Prone Position on Coronavirus Disease 2019 Pneumonia (Prone Position) |
Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia |
conventional oxygen therapy alone, prone position alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sisli Etfal Hospital |
|
Turkey |
2020-06-05 |
2020-06-15 |
NCT04427969, PP34 |
Phase Not Applicable |
Recruiting |
1 |
|
40 |
ayse surhan cinar, mustafa altinay, nebia peker |
2020-06-15 |
| MI-COVID: Predictive Factors COVID-19 Patients |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Milano-Bicocca |
|
Italy |
2020-03-01 |
2021-05-31 |
MI-COVID, MI-COVID, NCT04427345 |
Phase Not Applicable |
Recruiting |
1 |
15 Months |
1000 |
Paolo Bonfanti, Paolo Bonfanti, Professor |
2020-06-15 |
| Saliva/Nares as Source of Detection for SARS-CoV-2 at NIH |
Coronavirus disease 19 infection |
COVID-19 screening alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Institutes of Health Clinical Center |
|
US |
2020-06-22 |
2021-06-01 |
20-CC-0128, 200128, NCT04424446 |
Phase Not Applicable |
Recruiting |
1 |
11 Months |
5000 |
Karen M Frank, M.D., Rebecca A Nebel, Ph.D. |
2020-06-18 |
| COVID-19 Antibodies Among Healthcare Workers |
Coronavirus disease 19 infection |
COVID-19 IgG/IgM rapid test Cassette test (Healgen Scientific, Houston, Texas, USA) alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Universitario Dr. Jose E. Gonzalez |
|
Mexico |
2020-05-05 |
2020-06-01 |
IF20-00008, NCT04425889 |
Phase Not Applicable |
Completed |
1 |
|
156 |
Dr. Adrian Camacho-Ortiz |
2020-06-15 |
| Safety, Tolerability, and Efficacy of Anti-Spike (S) SARS-CoV-2 Monoclonal Antibodies for Hospitalized Adult Patients With COVID-19 |
Coronavirus disease 19 infection |
Face mask alone, High-intensity oxygen therapy alone, Low-flow oxygen therapy alone, Mechanical ventilation alone, Nasal cannula alone, REGN-CoV2 alone |
COVID19 Spike glycoprotein inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Regeneron Pharmaceuticals Inc |
|
US |
2020-06-12 |
2021-03-03 |
NCT04426695, R10933-10987-COV-2066 |
Phase 1/Phase 2 Clinical |
Recruiting |
1 |
8 Months |
1860 |
Clinical Trial Management, Clinical Trials Administrator, Dr. Suraj Saggar |
2020-06-17 |
| DOLCI: Darunavir/Cobicistat versus Lopinavir/Ritonavir in COVID-19 Pneumonia in Qatar |
Coronavirus disease 19 infection, Viral pneumonia |
darunavir + cobicistat (fixed dose, HIV infection), Janssen R&D/ Gilead alone, lopinavir + ritonavir alone |
Cytochrome P450 3 inhibitor, HIV protease inhibitor, HIV-1 protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hamad Medical Corp |
|
Qatar |
2020-03-01 |
2020-09-30 |
DOLCI, MRC-05-069, NCT04425382 |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
200 |
Dr. Eman Elmekaty, PharmD |
2020-06-15 |
| A phase I trial of SARS-CoV-2 virus-neutralizing mAbs (COVID-19), AstraZeneca/ VUMC for SARS-CoV-2 virus |
Coronavirus disease 19 infection |
SARS-CoV-2 virus-neutralizing mAbs (COVID-19), AstraZeneca/ VUMC alone |
|
|
AstraZeneca plc |
US Department of Defense, Vanderbilt University |
|
|
|
|
Phase 1 Clinical |
Planned |
0 |
|
|
|
2020-06-12 |
| INHIXACOV19: Enoxaparin in COVID-19 Moderate-to-Severe Hospitalized Patients |
Coronavirus disease 19 infection, Multiple organ failure, Respiratory failure, Septic shock, Thrombosis, Viral pneumonia |
enoxaparin sodium biosimilar, Techdow alone, standard thromboprophylaxis alone |
Low molecular weight heparin |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Policlinico S.Orsola-Malpighi |
|
Italy |
2020-05-22 |
2020-10-30 |
2020-001308-40, INHIXACOV19, NCT04427098 |
Phase 2 Clinical |
Recruiting |
13 |
5 Months |
300 |
Andrea Romagnoli, MD, Antonella Castagna, MD, Aria Patacca, MD, Arturo Montineri, MD, Elena Giovanna Bignami, MD, Elvira Grandone, MD, Evelina Tacconelli, MD, Francesco Cristini, MD, Fulvia Mazzaferri, MD, Giovanni Di Perri, MD, Giulio De Stefano, MD, Maddalena Giannella, MD, Marco Baciarello, MD, Marco Mangiafico, MD, Massimo Salvetti, MD, Pierluigi Viale, MD, Raffaello Bellosta, MD, Renzo Rossini, MD, Salvatore Casari, Sophie Testa, MD, Stefano Bonorq, MD, Stefano Triscornia, BS |
2020-06-18 |
| COVID-19GAOM: RT-PCR SARS-CoV-2 at 1 Month of COVID-19 Infection in the Geriatric Population |
Coronavirus disease 19 infection |
RT-PCR SARS-CoV-2 test alone |
|
Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hopitaux Universitaires de Strasbourg |
|
France |
2020-05-07 |
2020-08-31 |
7838, COVID-19GAOM, NCT04427358 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
100 |
Maxence MEYER, MD, Saïd CHAYER, PhD, HDR |
2020-06-15 |
| STORM: The Natural History of Hospitalized COVID-19 Patients |
Coronavirus disease 19 infection, Inflammatory disease, Lung infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Milano-Bicocca |
|
Italy |
2020-02-23 |
2020-12-31 |
NCT04424992, STORM, STORM |
Phase Not Applicable |
No longer recruiting |
1 |
10 Months |
1433 |
|
2020-06-15 |
| Accelerated LFR for Bipolar Patients During the COVID-19 Pandemic |
Bipolar I disorder, Bipolar II disorder, Coronavirus disease 19 infection |
Accelerated low-frequency right-sided stimulation protocol alone, B70 Fluid-Cooled Coil alone, MagPro X100 Stimulator alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre for Addiction and Mental Health |
|
Canada |
2020-06-09 |
2022-12-31 |
071-2020, NCT04427137 |
Phase Not Applicable |
Recruiting |
1 |
30 Months |
50 |
Daniel Blumberger, MD, Dov Millstone, Hannah Taalman |
2020-06-16 |
| Utility of Lactoferrin as a Preventive Agent for Healthcare Workers Exposed to COVID-19 |
Coronavirus disease 19 infection |
lactoferrin alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Cairo University |
|
Egypt |
2020-07-31 |
2020-11-30 |
CUKA-002, NCT04427865 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
4 Months |
200 |
Gamal Esmat |
2020-06-16 |
| Core Warming of COVID-19 Patients |
Coronavirus disease 19 infection |
core warming alone, ensoETM device alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Washington University in St Louis |
|
US |
2020-06-30 |
2020-11-30 |
202005150, NCT04426344 |
Phase Not Applicable |
Not yet recruiting |
1 |
5 Months |
20 |
Anne Drewry, MD, Katie Dalton |
2020-06-15 |
| ILIAD-7-US-O: InterLeukin-7 to Improve Clinical Outcomes in Lymphopenic patients With COVID-19 Infection |
Coronavirus disease 19 infection, Lymphocytopenia, Respiratory failure |
CYT-107 alone |
IL-7 receptor agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Revimmune Inc |
Amarex Clinical Research, Memorial Sloan-Kettering Cancer Center |
US |
2020-06-22 |
2020-12-31 |
ILIAD-7 COVID US ONCO, ILIAD-7-US-O, NCT04426201 |
Phase 2 Clinical |
Not yet recruiting |
1 |
6 Months |
48 |
Frederique Berbille, MHSc, Marcel van den Brink, MD, PhD, Michel MORRE, DVM, Steve Pastores, MD |
2020-06-15 |
| CRI-CP: Effectiveness and Safety of Convalescent Plasma in Patients With High-risk COVID-19 |
Coronavirus disease 19 infection, Multiple organ failure, Respiratory disease, Respiratory failure, Septic shock, Viral pneumonia |
convalescent plasma alone, standard care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fundacion Santa Fe De Bogota |
|
Colombia |
2020-07-31 |
2021-02-28 |
CRI-CP, NCT04425837, PLASMA COVID-19 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
7 Months |
236 |
Guillermo E Quintero, Hematologist, Guillermo Enrique Quintero-Vega, José A De la Hoz, Epidemiologist, José De la Hoz, Epidemiologist |
2020-06-15 |
| Effect of Covid-19 Epidemic on Primary PCI in Patients With STEMI |
Coronavirus disease 19 infection, Myocardial infarction |
percutaneous coronary intervention (PCI) alone |
|
|
Beijing Friendship Hospital |
|
China |
2019-01-24 |
2021-07-24 |
BFH-COVID-19 AND PRIMARY PCI, NCT04427735 |
Phase Not Applicable |
Recruiting |
1 |
30 Months |
200 |
Hongwei Li, Hongwei Li, MD, Hongwei Li, doctor, Xuhe Gong |
2020-06-15 |
| Ivermectin In Treatment of COVID-19 Patients |
Coronavirus disease 19 infection |
ivermectin alone |
Chloride channel modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ministry of Health and Population |
|
Egypt |
2020-06-09 |
2020-09-01 |
14-2020/3, NCT04425707 |
Phase 2 Clinical |
Recruiting |
1 |
2 Months |
100 |
ehab ah kamal, MD, houssam ho masoud, MD, noha mo asem, MD |
2020-06-15 |
| COVEMUZ: SARS-COV-2 Seroprevalence and Seroconversion Among Employees of the Universitair Ziekenhuis Brussel During the 2020 COVID-19 Outbreak |
Coronavirus disease 19 infection |
blood sampling alone, questionnaire alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universitair Ziekenhuis Brussel |
|
Belgium |
2020-05-12 |
2021-05-12 |
COVEMUZ, COVEMUZ, NCT04426292 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
3500 |
Laurien De Greef, Nurse, Sabine Allard, MD |
2020-06-15 |
| HOT-COVID: Handling Oxygenation Targets in COVID-19 |
Coronavirus disease 19 infection, Hypoxia, Respiratory failure |
oxygen alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Aalborg Universitetshospital |
Copenhagen Trial Unit, Rigshospitalet, Denmark |
Denmark |
2020-08-01 |
2024-03-01 |
2017-000632-34, AAUH-ICU-03, HOT-COVID, NCT04425031 |
Phase 4 Clinical |
Not yet recruiting |
1 |
43 Months |
780 |
Bodil Steen Rasmussen, MD, PhD, Olav Lilleholt Schjørring, MD, PhD, Thomas Lass Klitgaard, MD |
2020-06-17 |
| CORONEVRAXE: Study of the Sars-Cov2 Neuroinvasiveness - COVID-19 |
Coronavirus disease 19 infection, Neurological disease |
cerebrospinal fluid sampling alone, meningeal and brain parenchyma biopsies alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fondation Ophtalmologique Adolf De Rothschild |
|
France |
2020-06-30 |
2022-06-30 |
CORONEVRAXE, NCT04427254, PBN_2020_16 |
Phase Not Applicable |
Not yet recruiting |
1 |
24 Months |
500 |
Amélie YAVCHITZ, MD, Pierre BOURDILLON, MD |
2020-06-15 |
| PLACO-COVID: Standard or Convalescent Plasma in Patients With Recent Onset of COVID-19 Respiratory Failure |
Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure |
COVID-19 convalescent plasma alone, standard plasma alone, standard therapy protocol alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Azienda Ospedaliera Citta della Salute e della Scienza di Torino |
|
Italy |
2020-06-15 |
2021-12-15 |
CS3/33, NCT04428021, PLACO-COVID |
Phase 2 Clinical |
Not yet recruiting |
1 |
18 Months |
180 |
Paola Maria Manzini |
2020-06-15 |
| CORhum: Morbimortality of Covid-19 in Patients With Chronic Inflammatory Rheumatism Treated With Immunosuppressants |
Coronavirus disease 19 infection, Rheumatoid arthritis, Spondylarthritis, Systemic lupus erythematosus |
questionnaire assesment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Regional Universitaire de Lille |
|
France |
2020-08-31 |
2020-12-31 |
2020-A01650-39, CORhum, EQ2020_04, NCT04426279 |
Phase Not Applicable |
Not yet recruiting |
1 |
4 Months |
1500 |
Jean-Guillaume Letarouilly, MD |
2020-06-15 |
| MK-5475 in Participants With Hypoxemia Due to COVID-19 Pneumonia |
Coronavirus disease 19 infection, Hypoxia, Viral pneumonia |
MK-5475 alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Merck Sharp & Dohme Corp |
|
|
2020-07-07 |
2020-11-10 |
2020-002062-14, 5475-009, MK-5475-009, NCT04425733 |
Phase 1 Clinical |
Not yet recruiting |
0 |
4 Months |
64 |
Medical Director |
2020-06-15 |
| CRISIS: Safety and Anti-coronavirus Response of Suppression of Host Nucleotide Synthesis in Patients With COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
brequinar alone, standard of care alone |
Dehydrogenase inhibitor, Dihydroorotate dehydrogenase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Clear Creek Bio, Inc |
|
US |
2020-06-12 |
2020-10-31 |
CCB-CRISIS-01, CRISIS, NCT04425252 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
3 |
4 Months |
24 |
Barbara L Powers, Ph.D, Gerard J Criner, MD, James S Pope, MD, Karel Calero, MD, Samuel Pope, MD |
2020-06-17 |
| CARDS: Cancer: Rapid Diagnostics and Immune Assessment for SARS-CoV-2 (COVID-19) |
Advanced solid tumor, Coronavirus disease 19 infection, Lymphoma |
antigen lateral flow assay alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The Royal Marsden NHS Trust |
Mologic Ltd, NIHR Biomedical Research Centre, Oxford, St Georges University of London, The Royal Marsden Cancer Charity |
UK |
2020-05-26 |
2021-04-30 |
20/NE/0139, CARDS, CCR 5287, NCT04427280 |
Phase Not Applicable |
Recruiting |
1 |
11 Months |
60 |
David Lau, MBBS FRACP, Shannon Kidd, Sheela Rao, MD FRCP, Sue Cromarty |
2020-06-15 |
| A multicenter, randomized, double-blind, parallel-arm, placebo-controlled, phase II/III clinical study to assess opaganib in patients hospitalized with severe SARS-CoV-2 infection and pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
opaganib alone, standard-of-care alone |
Dihydroceramide delta 4 desaturase inhibitor, Sphingosine kinase 2 inhibitor |
|
RedHill Biopharma Ltd |
|
Russian Federation, Europe |
|
|
|
Phase 2/Phase 3 Clinical |
Planned |
1 |
|
270 |
|
2020-06-12 |
| A Phase II Trial of Infliximab in Coronavirus Disease 2019 (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Variable regimens including Tylenol , diphenhydramine , infliximab , infliximab biosimilar, Samsung Bioepis/ Merck & Co , prednisone |
TNF alpha ligand inhibitor, TNF binding agent |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tufts Medical Center |
National Institutes of Health |
US |
2020-06-01 |
2020-12-31 |
NCT04425538, STUDY00000564 |
Phase 2 Clinical |
Recruiting |
1 |
7 Months |
17 |
Christian Lawlor, Jaime Chisholm, Paul Mathew, MD |
2020-06-15 |
| Safety, Tolerability, and Efficacy of Anti-Spike (S) SARS-CoV-2 Monoclonal Antibodies for the Treatment of Ambulatory Adult Patients With COVID-19 |
Coronavirus disease 19 infection |
REGN-CoV2 alone |
COVID19 Spike glycoprotein inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Regeneron Pharmaceuticals Inc |
|
US |
2020-06-09 |
2020-11-21 |
NCT04425629, R10933-10987-COV-2067 |
Phase 1/Phase 2 Clinical |
Recruiting |
1 |
5 Months |
1054 |
Clinical Trial Management, Clinical Trials Administrator |
2020-06-17 |
| A randomized, placebo-controlled, phase III clinical trial to assess losmapimod the treatment of patients with COVID-19 |
Coronavirus disease 19 infection |
losmapimod alone |
Double homeobox protein 4 inhibitor, p38 MAP kinase alpha inhibitor, p38 MAP kinase beta inhibitor, p38 MAP kinase inhibitor |
|
Fulcrum Therapeutics Inc |
|
US |
|
|
|
Phase 3 Clinical |
Planned |
1 |
|
|
|
2020-06-12 |
| A study to evaluate the clinical characteristics and epidemiological trend of COVID-19 infected children with or without GI symptoms |
Coronavirus disease 19 infection |
|
|
|
The University of Hong Kong |
Wuhan medical care center for women and children |
Hong Kong |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
244 |
Dr Kenneth Wong Kak-yuen |
2020-06-12 |
| MRCS: 'Minority and Rural Health Coronavirus Study (MRCS)' to evaluate the impact of COVID-19 on racial minorities and underserved communities across the country |
Coronavirus disease 19 infection |
|
|
|
Centene Corp, National Minority Quality Forum (NMQF), Quest Diagnostics Inc |
|
US |
2020-06-30 |
|
MRCS |
Phase Not Applicable |
Not yet recruiting |
1 |
|
5000 |
Alan Morgan, Elizabeth Ofili, Gary Puckrein, Gloria Wilder, Latrice Landry, Richard Beswick, Salaheddin Mahmud, Suja M. Mathew, Thomas LaVeist, Vin Gupta, William A. Meyer |
2020-06-12 |
| DOD: A Multicenter, Randomized-Controlled trial to Assess the Safety and Efficacy of Seraph 100 Microbind Affinity Blood Filter (Seraph 100) in the treatment of critically-ill COVID-19 patients |
Coronavirus disease 19 infection |
Seraph 100 Microbind Affinity Blood Filter alone |
|
|
ExThera Medical LLC |
US Department of Defense |
US, Europe |
|
|
DOD |
Phase Not Applicable |
Planned |
2 |
|
|
|
2020-06-11 |
| An multi-national multicenter clinical trial of YS-SC2-010 for the treatment of Coronavirus disease 19 infection |
Coronavirus disease 19 infection |
YS-SC2-010 alone |
|
|
Yisheng Biopharma Co Ltd |
|
Europe, US, South East Asia, China |
|
|
|
Phase Not Applicable |
Planned |
2 |
|
|
|
2020-06-11 |
| A clinical study to evaluate the safety and tolerability of TY-027 for the treatment of COVID-19 |
Coronavirus disease 19 infection |
TY-027, Tychan alone |
|
Healthy volunteers accepted |
Tychan Pte Ltd |
|
|
|
|
|
Phase 1 Clinical |
Recruiting |
0 |
|
23 |
|
2020-06-15 |
| A clinical proof-of-concept study to assess SARS-CoV-2-specific virus-neutralizing antibodies for the potential treatment of COVID-19 |
Coronavirus disease 19 infection |
SARS-CoV-2-neutralizing monoclonal antibodies (COVID-19), Memo Therapeutics alone |
|
|
Memo Therapeutics AG |
|
|
2020-12-31 |
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-06-11 |
| An observation study to assess the effect of favipiravir in hospitalized patients with COVID-19 |
Coronavirus disease 19 infection |
favipiravir alone |
RNA polymerase inhibitor |
|
Fujita Health University |
|
Japan |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
|
|
2020-06-11 |
| A clinical study of anti-SARS-CoV-2 spike glycoprrotein monoclonal antibody (COVID-19), Celletrion for the treatment of COVID-19 |
Coronavirus disease 19 infection |
S-protein modulator (COVID-19), Celletrion alone |
Moesin modulator |
|
Celltrion Healthcare Co Ltd |
|
|
2020-07-31 |
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-06-15 |
| PI-Covid-19: Primary Prevention of Infection by COVID-19 in Health Providers |
Coronavirus disease 19 infection |
immunostimulant therapy alone, Variable regimens including allicin , eugenol , quercetin |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Unidad de Investigación Genética Molecular |
Universidad de Antioquia |
Colombia |
2020-07-31 |
2020-09-30 |
NCT04420260, PI-Covid-19, UNIGEM PT-IC-02 |
Phase 2 Clinical |
Not yet recruiting |
1 |
2 Months |
300 |
Beatriz H Aristizabal, PhD, Clara I Aristizabal, CEO, Clara Ines Aristizaba |
2020-06-11 |
| A trial to assess LVRNA-009 for COVID-19 vaccine |
Coronavirus disease 19 infection |
LVRNA-009 alone |
COVID19 Spike glycoprotein modulator |
|
Zhuhai Lifanda Biotechnology Co Ltd |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-06-11 |
| COVID-19-Related Health and Infection Control Practices Among Dentists |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
American Dental Association Foundation |
|
US |
2020-06-08 |
2021-06-08 |
20-08, NCT04423770 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
4000 |
Cameron G Estrich, MPH, PhD, Marcelo Araujo, DDS, MS, PhD |
2020-06-12 |
| QuadraMune for Prevention of COVID-19 |
Coronavirus disease 19 infection |
QuadraMune alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Therapeutic Solutions International Inc |
|
US |
2020-06-08 |
2020-11-08 |
NCT04421391, QUADRAMUNE002 |
Phase 2 Clinical |
Recruiting |
1 |
5 Months |
500 |
James Veltmeyer, MD, Thomas E Ichim, Thomas E Ichim, Ph.D |
2020-06-11 |
| BISCUIT: Bromhexine And Spironolactone For Coronаvirus Infection Requiring Hospitalization |
Coronavirus disease 19 infection, Viral pneumonia |
bromhexine plus spironolactone |
Aldosterone antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
MV Lomonosov Moscow State University |
|
Russian Federation |
2020-05-16 |
2020-08-23 |
BISCUIT, MSU160520, NCT04424134 |
Phase 3 Clinical |
Recruiting |
1 |
3 Months |
80 |
Julia Begrambekova, Julia Begrambekova, Phd, Yana Orlova, Professor |
2020-06-11 |
| Needs of Persons With Spinal Cord Injury (SCI) |
Coronavirus disease 19 infection, Spinal cord injury |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Washington University School of Medicine, US |
|
US |
2020-05-22 |
2020-12-31 |
202005026, NCT04422769 |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
250 |
Kerri A Morgan, PhD, Kimberly A Walker, OTD |
2020-06-11 |
| A clinical study to assess COVID-19 mRNA vaccine in the treatment of subjects with COVID-19 |
Coronavirus disease 19 infection |
mRNA vaccine (LPP delivery platform, COVID-19), Shanghai Yinuosi Biotechnology/Tongji University/Biocad/Stemrina Therapeutics alone |
|
|
Stemirna Therapeutics Co Ltd |
GenScript Biotech Corp |
China |
|
|
|
Phase Not Applicable |
Planned |
1 |
|
|
|
2020-06-11 |
| Acute Infection in Mitochondrial Disease: Metabolism, Infection and Immunity During the COVID19 Pandemic |
Coronavirus disease 19 infection, Infectious disease, Mitochondrial disease |
|
|
Healthy volunteers accepted, Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Human Genome Research Institute |
National Institutes of Health Clinical Center |
US |
2020-06-19 |
2025-05-01 |
20-HG-N120, 999920120, NCT04419870 |
Phase Not Applicable |
Not yet recruiting |
1 |
58 Months |
200 |
Eliza M Gordon-Lipkin, M.D., Shannon Kruk, Shannon Kruk, R.N. |
2020-06-17 |
| SANCO: A Saudi Arabia based study into the impact of coronavirus infection on the nervous system |
Ataxia, Cerebrovascular disease, Coronavirus disease 19 infection, Muscle injury, Neuropathic pain, Seizure disorder, Taste disorder, Vision disorder |
RT-PCR alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
King Saud Medical City |
|
Saudi Arabia |
2020-03-01 |
2021-02-28 |
ISRCTN15475176, KSMC, IRB, H1RI-24-MAY20-01, SANCO |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
1000 |
Prof Karakitsos |
2020-06-17 |
| CAPRI: Effects of COVID-19 Convalescent Plasma (CCP) on Coronavirus-associated Complications in Hospitalized Patients |
Coronavirus disease 19 infection |
ABO compatible anti-SARS-CoV-2 convalescent fresh frozen plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of California San Francisco |
Blood Systems Inc, San Francisco General Hospital |
US |
2020-06-08 |
2021-04-30 |
20-30794, CAPRI, NCT04421404 |
Phase 2 Clinical |
Recruiting |
1 |
10 Months |
30 |
Annie Leutkemeyer, MD, Brian Graham, MD, Carolyn Hendrickson, MD, Jonathan Esensten, MD, Kelvin Moore, BA, Kelvin Moore, BS, Lisa Winston, MD, Priscilla Hsue, MD, Rachel Bystritsky, MD, Rebecca Park, MA, Rebecca Park, MS, Vivek Jain, MD |
2020-06-18 |
| The effects of restricting going out on patients with chronic respiratory disease |
Coronavirus disease 19 infection, Respiratory disease |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Asahi Rosai Hospital |
|
Japan |
2020-06-12 |
|
UMIN000040715 |
Phase Not Applicable |
Recruiting |
1 |
|
300 |
Tomohiro Kawaji |
2020-06-15 |
| LOWRAD-Cov19: Low Dose Radiotherapy for COVID-19 Pneumonitis |
Coronavirus disease 19 infection, Viral pneumonia |
radiotherapy alone |
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Clinico San Carlos |
|
Spain |
2020-05-01 |
2020-09-08 |
LOWRAD-COV19, LOWRAD-Cov19, NCT04420390 |
Phase Not Applicable |
Recruiting |
1 |
4 Months |
41 |
Manuel Gonzalo Vazquez Masedo, MD, PhD, Manuel Gonzalo Vazquez Masedo, MD,PhD, Manuel Gonzalo Vázquez Masedo, MD |
2020-06-15 |
| FRENCH ICU: Study of the Increase in ICU Beds Capacity During COVID-19 Pandemic in France |
Coronavirus disease 19 infection |
|
|
|
Centre Hospitalier Universitaire de Nimes |
|
France |
2020-05-06 |
2020-06-05 |
30RC20_0117, FRENCH ICU, NCT04420286 |
Phase Not Applicable |
Recruiting |
1 |
1 Month |
9000 |
Jean-Yves LEFRANT, Jean-Yves LEFRANT, MD, PhD |
2020-06-15 |
| RetroCov: Impact of the Covid-19 Pandemic on Gastrointestinal and Liver Diseases |
Coronavirus disease 19 infection, Decompensated liver cirrhosis, Gastrointestinal disease, Liver disease |
antiviral drug therapy alone |
|
|
Medical University of Graz |
|
Austria |
2020-06-15 |
2021-12-31 |
NCT04420637, RETROCOV, RetroCov |
Phase Not Applicable |
Not yet recruiting |
1 |
18 Months |
1000 |
Vanessa Stadlbauer, MD |
2020-06-14 |
| Study of ivermectin against COVID-19 |
Coronavirus disease 19 infection |
ivermectin alone, standard of care therapy alone |
Chloride channel modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Huvepharma Eood |
|
Bulgaria |
2020-05-15 |
|
2020-002091-12, HUVE-19-CT-001 |
Phase 2 Clinical |
Recruiting |
1 |
|
120 |
|
2020-06-13 |
| A Phase III clinical trial of NLP-21 for the treatment of COVID-19 |
Coronavirus disease 19 infection |
NLP-21 alone |
|
|
NovaLead Pharma Pvt Ltd |
|
India |
|
|
|
Phase 3 Clinical |
Not yet recruiting |
1 |
|
150 |
|
2020-06-11 |
| GETAFIX: A study comparing favipiravir versus standard of care management as an early treatment arm in COVID-19 Hospitalized patients |
Coronavirus disease 19 infection |
favipiravir alone, supportive care alone |
RNA polymerase inhibitor |
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
NHS Greater Glasgow and Clyde, University of Glasgow |
|
UK |
2020-05-20 |
|
2020-001904-41, GETAFIX, GETAFIX-2020 |
Phase 2 Clinical |
Recruiting |
1 |
|
|
Liz-Anne Lewsley |
2020-06-13 |
| Efficacy and Safety of Nitazoxanide 600 mg, tid for the Treatment of Hospitalized Patients With COVID-19 |
Coronavirus disease 19 infection, Respiratory failure |
nitazoxanide (Viranitta) alone, standard of care alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Azidus Brasil |
Farmoquimica SA, Vera Cruz Casa de Saúde Campinas |
|
2020-07-31 |
2020-08-31 |
NCT04423861, NITFQM0520OR |
Phase 2 Clinical |
Not yet recruiting |
0 |
1 Month |
50 |
Florentino de Araujo Cardoso Filho, MD, PhD, Luciana Ferrara |
2020-06-15 |
| Efficacy of Chloroquine or Hydroxychloroquine in Treating Pneumonia Caused by SARS-Cov-2 - COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
standard treatment alone, chloroquine plus hydroxychloroquine |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centro de Estudos e Pesquisa em Emergencias Medicas e Terapia Intensiva |
|
Brazil |
2020-04-16 |
2020-06-01 |
CLOROTRIAL, NCT04420247 |
Phase 3 Clinical |
Suspended |
1 |
1 Month |
54 |
ALVARO REA-NETO, MD |
2020-06-15 |
| Preemptive Therapy for SARS-Coronavirus-2 (COVID-19 PEP Canada) |
Coronavirus disease 19 infection |
hydroxychloroquine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
McGill University Health Center, Research Institute of the McGill University Health Centre |
Eastern Health, Lawson Health Research Institute, McMaster University, University of Alberta, University of British Columbia, University of Manitoba, University of Minnesota |
US, Canada |
2020-03-25 |
2020-08-26 |
2020-6549, NCT04421664 |
Phase 3 Clinical |
Recruiting |
8 |
5 Months |
1500 |
Emily G McDonald, MD MSc, Glen Drobot, MD, Ilan Schwartz, MD, Lauren E Kelly, PhD, Lauren MacKenzie, MD, Matthew P Cheng, MD, Michael Silverman, MD, Peter Daley, MD MSc, Ryan Zarychanski, MD, Sara Belga, MD, Sylvain Lother, MD, Todd C Lee, MD MPH FIDSA, Zain Chagla, MD |
2020-06-15 |
| Hydroxychloroquine in comparison with hydroxychloroquine + azithromycin in patients with covid-19 |
Coronavirus disease 19 infection |
azithromycin plus hydroxychloroquine |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shahid Beheshti University |
|
Iran |
2020-05-19 |
|
IR.SBMU.RETECH.REC.1399.069, IRCT20200428047228N2 |
Phase 3 Clinical |
Recruiting |
1 |
|
40 |
Dr. Mohammad Fathi, ِDr.Mohammad Fathi |
2020-06-15 |
| Pentaglobin effect in critically ill patients with COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
Anticoagulant therapy alone, oxygen therapy alone, pentaglobin alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shahid Beheshti University of Medical Sciences, Laser Application in Medical Sciences Research Center |
|
Iran |
2020-06-22 |
|
IR.SBMU.NRITLD.REC.1399.014, IRCT20151227025726N18 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
30 |
Farzaneh Dastan, Payam Tabarsi |
2020-06-12 |
| COPROS study: COVID-19 in professional soccer players |
Coronavirus disease 19 infection |
|
|
|
Amphia Hospital |
|
Netherlands |
2020-05-18 |
2020-09-01 |
COPROS study, NL8685, W20.108 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
140 |
Jan Kluytmans |
2020-06-15 |
| COVID-19 treatment outcomes at the University Medical Center Freiburg |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Albert-Ludwigs-Universität Freiburg |
|
Germany |
2020-05-31 |
|
DRKS00021775 |
Phase Not Applicable |
Recruiting |
1 |
|
400 |
Mr. Prof. Dr. Siegbert Rieg |
2020-06-12 |
| TMD: Targeted Melanoma Detection With Skin Self-Examination During COVID-19 Restricted Physician Access |
Coronavirus disease 19 infection, Melanoma |
Home sample collection of concerning mole with physician supervision alone, SSE educational intervention alone |
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Northwestern University |
|
US |
2020-06-15 |
2021-12-30 |
COVID_IMPACT, NCT04420273, STU00212165, TMD |
Phase Not Applicable |
Not yet recruiting |
1 |
18 Months |
1000 |
Dalya A Durst, June K Robinson, MD |
2020-06-15 |
| Maintenance Versus Reduction of Immunosuppression for Renal Transplant Patients Hospitalized With COVID-19 Disease |
Coronavirus disease 19 infection, Kidney transplantation |
Maintenance of immunosuppression alone, azathioprine alone, mycophenolate mofetil alone |
Inosine monophosphate dehydrogenase inhibitor, PurH purine biosynthesis protein inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Brigham & Women's Hospital |
|
US |
2020-07-01 |
2021-12-31 |
2020P001516, NCT04420364 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
18 Months |
50 |
Finnian R Mc Causland, MBBCh, MMSc, Jamil Azzi, MD, PhD |
2020-06-15 |
| Telematic Monitoring Through a Mobile Application of Patients With COVID-19 |
Coronavirus disease 19 infection |
Farmalarm alone, SMART PULSE OXIMETER OL-750 alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Vall D'Hebron |
|
Spain |
2020-03-31 |
2020-05-18 |
NCT04423289, PR(AG)182-2020 |
Phase Not Applicable |
Completed |
1 |
1 Month |
150 |
Oscar Len, MD, PhD |
2020-06-12 |
| External Dead Space in Ventilated Covid-19 Patients |
Coronavirus disease 19 infection |
apparatus dead space alone, mechanical ventilation alone, volumetric capnography alone |
|
|
Karolinska Institutet |
Stockholm County Council |
Sweden |
2020-06-07 |
2020-09-07 |
KAROLINSKA, NCT04424082 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
40 |
Björn Persson, MD PhD, Jacob Karlsson, MD PhD, Per-Arne Lönnqvist, Prof |
2020-06-15 |
| BREATH: Baricitinib for corona Virus pneumonia (COVID-19): a Therapeutic Trial |
Coronavirus disease 19 infection, Pneumonia |
baricitinib alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
IRCCS Policlinico San Matteo |
|
Italy |
2020-05-15 |
2020-11-15 |
2020-001185-11, BREATH, NCT04399798 |
Phase 2 Clinical |
Not yet recruiting |
1 |
6 Months |
13 |
Carlomaurizio Montecucco, Prof, Raffaele Bruno, Prof, Sara Monti, MD, Valentina Zuccaro, MD |
2020-06-12 |
| COVID-19 Virtual Care at Home |
Coronavirus disease 19 infection |
VIRTUES platform alone, Virtual Care at Home alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Lawson Health Research Institute |
Cardiac Arrhythmia Network of Canada |
Canada |
2020-06-08 |
2021-12-31 |
CTO 3210, NCT04420182 |
Phase Not Applicable |
Not yet recruiting |
1 |
18 Months |
2000 |
Anthony Tang, MD, Marko Mrkobrada, MD, Sabrina Wall |
2020-06-12 |
| Co-STAR: Coronavirus Smell Therapy for Anosmia Recovery |
Coronavirus disease 19 infection, Dysomia |
budesonide alone, high-concentration essential oil olfactory training alone, low-concentration essential oil olfactory training alone, nasal saline lavage alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Washington University School of Medicine, US |
|
US |
2021-06-01 |
2023-12-31 |
Co-STAR, NCT04422275, PA-18-334 |
Phase 2 Clinical |
Not yet recruiting |
1 |
31 Months |
200 |
Jay F. Piccirillo, MD |
2020-06-13 |
| A prospective, interventional, single-active-arm, single-center pilot trial of mavrilimumab for the treatment of patients with severe pneumonia and hyperinflammation associated with COVID-19 |
Coronavirus disease 19 infection, Inflammatory disease, Respiratory distress syndrome, Viral pneumonia |
mavrilimumab alone, standard of care therapy alone |
C-reactive protein inhibitor, Chemokine CC22 ligand inhibitor, GM-CSF receptor antagonist, Hemoglobin scavenger receptor antagonist, Metalloprotease-1 inhibitor, Metalloprotease-3 inhibitor, Small inducible cytokine A17 ligand inhibitor, VEGF gene inhibitor |
|
Kiniksa Pharmaceuticals Ltd |
|
Italy |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
13 |
Lorenzo Dagna |
2020-06-15 |
| A global, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of mavrilimumab in addition to standard of care therapy in the treatment of patients with severe COVID-19 pneumonia and hyperinflammation |
Coronavirus disease 19 infection, Lung inflammation, Viral pneumonia |
mavrilimumab alone, standard of care therapy alone |
C-reactive protein inhibitor, Chemokine CC22 ligand inhibitor, GM-CSF receptor antagonist, Hemoglobin scavenger receptor antagonist, Metalloprotease-1 inhibitor, Metalloprotease-3 inhibitor, Small inducible cytokine A17 ligand inhibitor, VEGF gene inhibitor |
|
Kiniksa Pharmaceuticals Ltd |
|
|
|
|
|
Phase 2/Phase 3 Clinical |
Planned |
0 |
|
580 |
|
2020-06-14 |
| A clinical trial to assess the safety and effectivness of Russian Coronavirus Vaccine in healthy volunteers |
Coronavirus disease 19 infection |
anti-coronavirus vaccine alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Ministry of Defence of the Russian Federation |
|
Russian Federation |
|
|
|
Phase Not Applicable |
Recruiting |
1 |
|
50 |
|
2020-06-11 |
| PULCO-19: Characterization of Persistent Pulmonary Abnormalities Following COVID-19 Pneumonia |
Coronavirus disease 19 infection, Lung injury, Viral pneumonia |
pulmonary anomaly test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire de Toulouse |
|
France |
2020-05-28 |
2022-05-31 |
NCT04422613, PULCO-19, RC31/20/0181 |
Phase Not Applicable |
Recruiting |
1 |
24 Months |
60 |
Elise Noël-Savina, MD |
2020-06-15 |
| Clinical Trial on the Efficacy and Safety of Bemiparin in Patients Hospitalized Because of COVID-19 |
Coronavirus disease 19 infection |
bemiparin alone |
Factor Xa antagonist, Heparin agonist, Low molecular weight heparin |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
HM Research Foundation Hospitals |
Syntax for Science |
Spain |
2020-06-04 |
2021-03-31 |
2020-001548-24, BEMICOVID-19, NCT04420299 |
Phase 2 Clinical |
Recruiting |
2 |
9 Months |
120 |
Antonio Cubillo, MD, Elena Nuñez Cuerda, MD, José Felipe Varona, MD |
2020-06-12 |
| Impact of Burnout on Cardiovascular and Immune Biomarkers in Healthcare Professionals - Covid-19 Pandemic in Abu Dhabi |
Cardiovascular disease, Coronavirus disease 19 infection, Immune disorder, Psychiatric disorder |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Khalifa University Of Science & Technology & Research (Kustar) |
Abu Dhabi University, AE, Cleveland Clinic Abu Dhabi, Mediclinic Middle East, Sheikh Khalifa Medical City, Sheikh Shakhbout Medical City, Zayed Military Hospital |
United Arab Emirates |
2020-06-14 |
2020-12-31 |
CPRA-2020-034, NCT04422418 |
Phase Not Applicable |
Recruiting |
4 |
6 Months |
200 |
Ahmad Mounir, MD, Hashel Al Tunaiji, MD MSc, Nadya Matroushi, MD, Ovidiu C Baltatu, MD PhD, Seema El Khider Nour, MD, Wael Almahmeed, MD |
2020-06-15 |
| C3PI: Murdock Cabarrus County COVID-19 Prevalence and Immunity (C3PI) Study |
Coronavirus disease 19 infection |
biological sampling alone, polymerase chain reaction alone, serological testing alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Duke University |
North Carolina Department of Health and Human Services |
US |
2020-06-15 |
2021-06-30 |
C3PI, NCT04424004, PRO00105703 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
500 |
Abha Singh, Carla Kingsburg, Kristin Newby, MD |
2020-06-12 |
| The Impact of COVID-19 on Dialysis Users |
Coronavirus disease 19 infection, End stage renal disease |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Portsmouth |
Portsmouth Hospitals, University of Reading |
UK |
2020-06-03 |
2020-09-03 |
004, NCT04422873 |
Phase Not Applicable |
No longer recruiting |
1 |
3 Months |
40 |
Dr Zoe Saynor, Senior Lecturer |
2020-06-11 |
| Utility of Lactoferrin as an Adjunct Therapeutic Agent for COVID-19 |
Coronavirus disease 19 infection |
Standard of care alone, lactoferrin alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Cairo University |
|
Egypt |
2020-06-30 |
2020-11-30 |
CUKA-001, NCT04421534 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
5 Months |
150 |
Gamal Esmat |
2020-06-11 |
| ACES: Angiotensin II Infusion in COVID-19-Associated Vasodilatory Shock: A multinational, multicenter registry |
Cardiogenic shock, Coronavirus disease 19 infection |
Angiotensin II alone, novel therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Austin Health |
Australian and New Zealand Intensive Care Research Centre, Monash University |
Canada, Australia, UK, Belgium, Germany, Italy |
2020-06-15 |
2020-12-30 |
ACES, ACTRN12620000620921 |
Phase Not Applicable |
Not yet recruiting |
9 |
6 Months |
315 |
Dr Ary Serpa Neto, Mr Tony Trapani, Prof Rinaldo Bellomo |
2020-06-12 |
| BEAT: Open label, prospective study for the Biofourmis Everion armband telemonitoring solution for patients during COVID-19 home isolation within South Western Sydney |
Coronavirus disease 19 infection |
Everion armband alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
South Western Sydney Local Health Network |
Ingham Institute for Applied Medical Research |
Australia |
2020-06-05 |
2020-09-30 |
ACTRN12620000635965, BEAT |
Phase Not Applicable |
Not yet recruiting |
6 |
3 Months |
50 |
Prof Josephine Chow |
2020-06-12 |
| Analysis of the Inflammatory Response and the Development of Humoral and Cellular Immunity in Patients With COVID-19 |
Coronavirus disease 19 infection |
|
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Coordinacion de Investigacion en Salud |
Instituto Mexicano del Seguro Social |
Mexico |
2020-04-15 |
2020-08-15 |
NCT04423640, R-2020, 3601-043 |
Phase Not Applicable |
Recruiting |
1 |
4 Months |
200 |
Constantino López Macías, PhD, Eduardo Ferat-Osorio, PhD, Suria Loza Jalil, MD |
2020-06-12 |
| A potential use of VAL-201 in a combination treatment for patients suffering a hyperimmune response to Coronavirus SARS-CoV2 infection |
Coronavirus disease 19 infection |
VAL-201 alone |
Src tyrosine kinase inhibitor |
|
Black Cat Bio Limited, Oncolytika Limited |
ValiRx plc |
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-06-10 |
| Knowledge, practices, and risk and susceptibility perceptions on exposure to COVID-19: A qualitative triangulation study on pregnant women, their spouses, and non-pregnant reproductive-aged women with healthcare workers in Metro Manila |
Coronavirus disease 19 infection |
|
|
|
Philippine General Hospital |
|
Philippines |
2020-05-26 |
2021-05-26 |
PHRR200604-002695 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
|
Erlidia F. Llamas-Clark, MD, MPH, PhD, Maria Stephanie Fay S. Cagayan, Maria Stephanie Fay S. Cagayan, MD |
2020-06-11 |
| SeniorCOVIDRea: Senior-COVID-Rea Multicentric Survey |
Coronavirus disease 19 infection |
blood sampling alone |
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospices Civils De Lyon |
|
France |
2020-04-01 |
2020-08-15 |
69HCL20-0386, NCT04422340, SeniorCOVIDRea |
Phase Not Applicable |
Recruiting |
5 |
4 Months |
185 |
Claire Falandry, MD, Max Haine, MD, Vincent COLLANGE, MD |
2020-06-17 |
| EPRICOD: Evaluation of the COVID-19 Infection Response in Patients Admitted to the Emergency Department for Dyspnea |
Coronavirus disease 19 infection, Dyspnea |
|
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire de Toulouse |
|
France |
2020-03-13 |
2021-06-30 |
EPRICOD, NCT04422587, RC31/20/0149 |
Phase Not Applicable |
No longer recruiting |
1 |
15 Months |
1860 |
Paul-Henri Auboiroux, MD |
2020-06-10 |
| PANDEMIC: Mental Health and Academic Performance in COVID-19 |
Anxiety disorder, Coronavirus disease 19 infection, Depression |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Instituto Mexicano del Seguro Social |
|
Mexico |
2020-04-01 |
2020-07-30 |
MENTAL01, NCT04420416, PANDEMIC |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
720 |
Alejandro Gonzalez Ojeda, PhD, Gonzalez Ojeda Alejandro |
2020-06-10 |
| ALTRISCOVID-19: Analysis of Long-Term Risk of Coronavirus Disease-19 Emergency |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Istituto Neurologico Mediterraneo NEUROMED |
|
Italy |
2020-06-08 |
2021-12-31 |
ALTRISCOVID-19, DEP 1/2020, NCT04422262 |
Phase Not Applicable |
Not yet recruiting |
1 |
18 Months |
10000 |
Licia Iacoviello, Licia Iacoviello, MD, PhD, Marialaura Bonaccio |
2020-06-11 |
| Tocilizumab in COVID-19 Positive Patients |
Coronavirus disease 19 infection, Inflammatory disease |
standard of care alone, tocilizumab (intravenous), Roche/Chugai alone |
IL-6 receptor antagonist, IL-6 receptor modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Calgary |
Roche Holding AG |
Canada |
2020-06-30 |
2021-06-30 |
NCT04423042, REB20-0713 |
Phase 3 Clinical |
Not yet recruiting |
1 |
12 Months |
30 |
Jacinda R Larson, PhD, Namneet Sandhu, MPH, Susanne Benseler, MD PhD |
2020-06-11 |
| SeroCOVIDial: Assessment of COVID-19 Seroconversion in Patients on Chronic Hemodialysis and in Their Caregivers, a Cohort Study |
Coronavirus disease 19 infection |
Biosynex serological test alone, seroconversion assay alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assistance Publique Hopitaux De Marseille |
|
France |
2020-06-05 |
2020-12-15 |
2020-34, 2020-A01515-34, NCT04420338, SeroCOVIDial |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
800 |
Jean-Olivier ARBAUD, Director, Noémie JOURDE-CHICHE, PU-PH, Philippe BRUNET, PU-PH |
2020-06-18 |
| CYTOAID: Data Analysis of the Cytokine Adsorption Treatment on Coronavirus Disease-19 (COVID-19) Patients With Respiratory Failure |
Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure |
CytoSorb alone, cytokine adsorption therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Of Pécs |
|
|
2020-07-01 |
2022-12-01 |
20802-5/2020/EUIG, CYTOAID, NCT04422626 |
Phase Not Applicable |
Not yet recruiting |
0 |
29 Months |
42 |
Péter Hegyi, MD, PhD, DSc, Péter Hegyi, MD, PhD, Dsc, Zsolt Molnár, MD, PhD, Dsc |
2020-06-13 |
| SEROPHUGAC: Serological Study of the Exposure of Personnel to Sars-cov-2 |
Coronavirus disease 19 infection |
RT-PCR alone, serology test alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Centre Hospitalier Saint Joseph Saint Luc de Lyon |
|
|
2020-06-08 |
2020-06-30 |
NCT04422977, SEROPHUGAC, SEROPHUGAC |
Phase Not Applicable |
Not yet recruiting |
0 |
|
900 |
|
2020-06-11 |
| SARS-CoV-2 PoC/ELISA: Evaluation of three commercially available rapid assays for detection of IgG and/or IGM antibodies to SARS-CoV-2 (COVID-19) for assessment of contact persons’ immune status and termination of quarantine and self-isolation – a prospective pilot study |
Coronavirus disease 19 infection |
COVID-19 antibody point-of-care test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Landesklinikum Neunkirchen |
|
Austria |
2020-05-20 |
|
DRKS00022083, GS1-EK-3/168-2020, SARS-CoV-2 PoC/ELISA |
Phase Not Applicable |
Recruiting |
1 |
|
70 |
Klaus Hackner |
2020-06-11 |
| SynCov: Synbiotic Therapy of Gastrointestinal Symptoms During COVID-19 Infection |
Coronavirus disease 19 infection, Diarrhea, Enteritis, Gastrointestinal disease |
Omnibiotic AAD alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Medical University of Graz |
|
Austria |
2020-08-31 |
2022-12-31 |
NCT04420676, SYNCOV, SynCov |
Phase Not Applicable |
Not yet recruiting |
1 |
28 Months |
108 |
|
2020-06-11 |
| COVID-EP: Cohort Comparing the Prevalence and Characteristics of Pulmonary Embolism on COVID-19 Patients Presenting Respiratory Symptoms |
Coronavirus disease 19 infection, Lung embolism, Respiratory disease, Respiratory distress syndrome, Viral pneumonia |
CT pulmonary angiogram alone, computed tomography alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Groupe Hospitalier Paris Saint-Joseph |
|
France |
2020-03-01 |
2020-04-20 |
COVID-EP, COVID-EP, MR 4516150520, NCT04420312 |
Phase Not Applicable |
Completed |
1 |
1 Month |
1024 |
|
2020-06-11 |
| Prophylactic Ivermectin in COVID-19 Contacts |
Coronavirus disease 19 infection |
ivermectin alone |
Chloride channel modulator |
Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Zagazig University |
|
Egypt |
2020-05-31 |
2020-07-31 |
NCT04422561, ZU-IRB-6150L31-5-2020 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
2 Months |
100 |
Waheed Shouman, Waheed Shouman, MD |
2020-06-11 |
| PICS-COVID19: Post Intensive Care Syndrome in COVID-19 Patients |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Corporacion Parc Tauli |
|
Spain |
2020-06-01 |
2022-06-01 |
2020/577, NCT04422444, PICS-COVID19 |
Phase Not Applicable |
Recruiting |
1 |
24 Months |
100 |
SOL FERNANDEZ, PhD, Sol Fernandez-Gonzalo, Sol Fernandez-Gonzalo, PhD |
2020-06-13 |
| IDENTIFY: Identification of a Responsive Subpopulation to Hydroxychloroquine in COVID-19 Patients Using Machine Learning |
Coronavirus disease 19 infection |
COViage alone |
|
|
Dascena |
|
US |
2020-03-10 |
2020-06-04 |
060820, IDENTIFY, NCT04423991 |
Phase 2 Clinical |
Completed |
1 |
2 Months |
290 |
|
2020-06-12 |
| Sero-prevalence of Coronavirus Disease 2019 (COVID-19) in Healthcare Workers |
Coronavirus disease 19 infection |
Ortho clinical diagnostics chemiluminescent technique alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Cairo University, Egyptian Center for Research and Regenerative Medicine |
Academy of Scientific Research and Technology, National Research Center Patent Office |
Egypt |
2020-06-16 |
2020-09-30 |
COVID-19\004, NCT04424017 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
726 |
Khaled Eissa Amer, MD |
2020-06-12 |
| Knowledge About Covid-19 Infection |
Coronavirus disease 19 infection |
counseling alone |
|
Healthy volunteers accepted, Female, Young Adults (18-44 yrs) |
Aljazeera Hospital |
|
Egypt |
2020-04-01 |
2020-06-20 |
KNOWLEDGE ABOUT COVID 19, NCT04423692 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
300 |
Mahmoud Alalfy, Mahmoud Alalfy, PhD |
2020-06-10 |
| QT-COVID-19: Effects on the Qt Interval of COVID-19 Coronavirus Infection |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital General Universitario Gregorio Marañon |
|
Spain |
2020-05-29 |
2020-12-01 |
NCT04422535, QT-COVID-19, QT-COVID-19 |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
80 |
Javier Hortal, MD PhD, Matilde Zaballos, Matilde Zaballos, MD, PhD, Matilde Zaballos, MDPhD |
2020-06-12 |
| CHRONOS19: Observational, Prospective, Cohort Study: Registry of Patients With Hematological Disease and COVID-19 in Russia |
Coronavirus disease 19 infection, Hematological disease, Hematological neoplasm |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hematology Research Center |
|
Russian Federation |
2020-06-08 |
2021-07-08 |
CHRONOS19, CHRONOS19, NCT04422470 |
Phase Not Applicable |
Not yet recruiting |
1 |
13 Months |
200 |
Olga Gavrilina, PhD |
2020-06-15 |
| ICOLS: Implications of Covid-19 on the Lifestyle Changes |
Coronavirus disease 19 infection |
online survey alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Azienda Unita Sanitaria Locale di Reggio Emilia |
|
Italy |
2020-05-04 |
2020-06-15 |
ICOLS, ICOLS_COVIDSTYLE, NCT04423978 |
Phase Not Applicable |
Recruiting |
1 |
1 Month |
1500 |
Elisa Mazzini, MD |
2020-06-15 |
| A phase II clinical trial to evaluate the efficacy of JS-016 in the treatment of patients with COVID-19 infection |
Coronavirus disease 19 infection |
JS-016 alone |
COVID19 Spike glycoprotein inhibitor |
|
Eli Lilly & Co, Shanghai Junshi Biosciences Co Ltd |
|
|
|
|
|
Phase 2 Clinical |
Planned |
0 |
|
|
|
2020-06-10 |
| COVID-19 and Liver Injury in Patients With or Without Underlying Liver Disease: A Multicenter, Retrospective-prospective, Observational Study |
Coronavirus disease 19 infection, Liver disease, Liver failure, Liver injury |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Max Healthcare Institute Ltd, India |
|
India |
2020-06-07 |
2020-08-30 |
COVID 19/LI/2020, NCT04422379 |
Phase Not Applicable |
Not yet recruiting |
1 |
2 Months |
314 |
Kaushal Madan, DM, Rajesh Saxena, Vivek Raj, DM |
2020-06-12 |
| PneumoSeroCov: COVID-19 Serology in Pulmonologists |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital, Montpellier |
|
France |
2020-05-01 |
2020-05-30 |
NCT04422574, PneumoSeroCov, RECHMPL20_0343 |
Phase Not Applicable |
Completed |
1 |
|
97 |
Arnaud Bourdin, MD PhD |
2020-06-15 |
| The Safety and Efficacy of Imatinib for the Treatment of SARS-COV-2 Induced Pneumonia |
Coronavirus disease 19 infection, Hypoxia, Respiratory distress syndrome, Respiratory failure, Viral pneumonia |
imatinib alone, standard treatment alone |
Abl tyrosine kinase inhibitor, Bcr protein inhibitor, Kit tyrosine kinase inhibitor, PDGF receptor antagonist, Signal transduction inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Alexandria |
Science, Technology and Innovation Funding Authority (STIFA) |
Egypt |
2020-06-30 |
2020-10-31 |
ALEX CCM 2020/5, NCT04422678 |
Phase 3 Clinical |
Not yet recruiting |
1 |
4 Months |
30 |
ASSAAD, MD, PhD, Hany ASSAAD, MD, PhD |
2020-06-12 |
| Endoscopic Interventions in Patients With COVID-19 |
Coronavirus disease 19 infection |
endoscopic intervention alone |
|
|
University Hospital Tubingen |
|
Germany |
2020-03-01 |
2020-05-15 |
242/2020BO2, NCT04423003 |
Phase Not Applicable |
Completed |
1 |
2 Months |
10 |
|
2020-06-11 |
| Thrombosis Risk Assessment and Clinical Presentation of Covid-19 Pneumonia |
Coronavirus disease 19 infection, Thrombosis, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Nisantasi University |
|
Turkey |
2020-06-30 |
2020-07-31 |
20200504443, NCT04423315 |
Phase Not Applicable |
Not yet recruiting |
1 |
1 Month |
70 |
Hasan Haciosman, M.D., Murat Civan, M.D. |
2020-06-12 |
| Investigational COVID-19 Convalescent Plasma Infusion for Severely or Life-threateningly Ill COVID-19 Patients |
Coronavirus disease 19 infection, Multiple organ failure, Respiratory failure, Septic shock |
COVID-19 convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Rutgers University |
University Hospital, Newark, New Jersey |
US |
|
|
NCT04420988, PRO2020000746, PRO2020000911 |
Phase Not Applicable |
Recruiting |
2 |
|
|
Khyati Mehta, MPH, Marc Klapholz, MD, MBA |
2020-06-15 |
| COVIDUS-NOR: Ultrasonography in Norwegian Emergency Department Patients With Suspected Covid-19 Infection |
Coronavirus disease 19 infection |
Ultrasonography alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
St Olavs Hospital |
Drammen Hospital, Haukeland University Hospital, Helse Stavanger HF, Nordlandssykehuset HF, Sorlandet Hospital, Sykehuset Telemark, Ullevaal University Hospital, University Hospital, Akershus |
Norway |
2020-07-01 |
2025-12-31 |
COVIDUS-NOR, NCT04422691, REK129805 |
Phase Not Applicable |
Not yet recruiting |
9 |
66 Months |
200 |
Anders B Martinsen, MD, Benedicte Severinsen, MD, Eirik H Ofstad, MD, PhD, Harry Achterberg, MD, Jay Shyamal Chotai, MD, Jørn Rasmussen, MD, Lars E Næss-Pleym, Lars Petter Bjørnsen, MD, PhD, Rune Bjørneklett, MD, PhD, Øistein Rønneberg Mjelva, MD, PhD |
2020-06-12 |
| Fibromyalgia During the Covid-19 Pandemic |
Coronavirus disease 19 infection, Fibromyalgia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Al-Azhar University |
|
Egypt |
2020-03-15 |
2020-06-30 |
AAGH-01, NCT04422522 |
Phase Not Applicable |
No longer recruiting |
1 |
3 Months |
45 |
Ahmed Abogamal |
2020-06-12 |
| PTT-Online: Video Dance Class and Unsupervised Physical Activity During Covid-19 Pandemic in People With Parkinson's Disease |
Coronavirus disease 19 infection, Parkinsons disease |
video dance classes alone |
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Federal University of Rio Grande do Sul |
|
Brazil |
2020-05-01 |
2024-12-30 |
NCT04422353, PTT-Online, PTT-PARKINSON/COVID19 |
Phase Not Applicable |
Recruiting |
1 |
55 Months |
60 |
Aline N. Haas, PhD, Elren P. Monteiro, PhD, Flávia G. Martinez, PhD, Leonardo A Peyré-Tartaruga, PhD, Leonardo A. Peyré-Tartaruga, Leonardo A. Peyré-Tartaruga, PhD |
2020-06-12 |
| COV-BARRIER: A Study of Baricitinib (LY-3009104) in Participants With COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
Background therapy alone, baricitinib alone |
Jak1 tyrosine kinase inhibitor, Jak2 tyrosine kinase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Eli Lilly & Co |
|
Mexico, Spain, Germany, US |
2020-05-29 |
2020-09-01 |
17830, 2020-001517-21, COV-BARRIER, I4V-MC-KHAA, NCT04421027 |
Phase 3 Clinical |
Recruiting |
15 |
3 Months |
400 |
Adrian Camacho Ortiz, Andrew Catanzaro, Dora Patricia Cornejo Juárez, Gustavo Rojas Velasco, Luis Enrique Soto Ramírez, Mark MacElwee, Michel Fernando Martínez Reséndez, Miriam Akasbi, Patrick Milligan, Phyllis Tien, Roberto Caricchio, Thomas Grunewald, Thomas Lawrie, Vicente Estrada, Vinay Malhotra |
2020-06-18 |
| HEART-COVID: Descriptive and Retrospective Analysis of Acute Myocarditis Associated With Pandemic COVID-19 in Children |
Coronavirus disease 19 infection, Myocarditis |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) |
Assistance Publique Hopitaux de Paris |
|
France |
2020-06-30 |
2020-12-31 |
APHP200632, HEART-COVID, NCT04420468 |
Phase Not Applicable |
Not yet recruiting |
4 |
6 Months |
20 |
Clémence Marais, MD, Hélène Morel, Julie Starck, MD, Marion Grimaud, Marion Grimaud, MD, Michäel Levy, MD, Sylvain Renolleau, MD, PhD |
2020-06-11 |
| PAPESCO-19: Patients and Health Staff of Cancer Centres During the Covid-19 Pandemic |
Coronavirus disease 19 infection |
ELISA alone, RT-PCR alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Institut De Cancerologie De L'Ouest |
|
France |
2020-06-15 |
2022-06-15 |
ICO-2020-16, NCT04421625, PAPESCO-19 |
Phase Not Applicable |
Not yet recruiting |
1 |
24 Months |
12000 |
Magali Briere, Magali Brière, Michele Boisdron-Celle, Michelle Boisdron-Celle |
2020-06-11 |
| Magnetic Resonance Imaging to Detect Signs of Viral Pneumonia in Patients With Coronavirus Infection |
Coronavirus disease 19 infection, Lung injury, Viral pneumonia |
chest magnetic resonance imaging alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Research and Practical Center of Medical Radiology, Department of Health Care of Moscow |
|
Russian Federation |
2020-05-19 |
2021-06-20 |
2020-2, NCT04424355 |
Phase Not Applicable |
Recruiting |
1 |
13 Months |
115 |
Olga Panina, Sergey Morozov, Yuri Vasilev |
2020-06-17 |
| FCFM: Forecasting COVID-19 for Malaysia |
Coronavirus disease 19 infection |
|
|
|
Government of Malaysia |
|
Malaysia |
2020-06-05 |
2022-05-31 |
FCFM, NMRR-20-1109-54838 |
Phase Not Applicable |
Not yet recruiting |
1 |
23 Months |
|
Devi Peramalah, Prof. Dr Jamalludin Ab Rahman |
2020-06-11 |
| A phase II trial to assess Metablok in the prevention of acute organ inflammation and injury experienced by patients with COVID-19 |
Acute lung injury, Coronavirus disease 19 infection, Inflammatory disease, Renal injury, Respiratory distress syndrome |
Metablok alone |
Dehydropeptidase-1 modulator |
|
Arch Biopartners Inc |
|
US |
|
|
|
Phase 2 Clinical |
Planned |
1 |
|
|
|
2020-06-10 |
| DRDMMICPINSL |
Coronavirus disease 19 infection |
Robust Disease Modelling alone |
|
|
Government of Malaysia |
|
Malaysia |
2020-06-04 |
2022-05-31 |
54839, NMRR-20-1102-54839 |
Phase Not Applicable |
Not yet recruiting |
1 |
23 Months |
|
Devi Peramalah, he agent-based model |
2020-06-11 |
| PICOVID |
Coronavirus disease 19 infection |
povidone iodine alone |
|
|
Hospital Sungai Buloh |
|
Malaysia |
2020-06-05 |
2020-07-01 |
54946, NMRR-20-1099-54946 |
Phase 2 Clinical |
Status not specified |
1 |
|
60 |
Dr Shiraz Qamil bin Muhammad Abdul Kadar, dr IFFAH BINTI SALIM |
2020-06-11 |
| A randomized, double-blind, placebo-controlled, phase II study to assess the longer-term efficacy and safety pamrevlumab in patients who recovered or are recovering from COVID-19 infection with evidence of interstitial lung disease |
Coronavirus disease 19 infection, Interstitial lung disease |
pamrevlumab alone |
Connective tissue growth factor ligand inhibitor |
|
FibroGen Inc |
|
US |
|
|
|
Phase 2 Clinical |
Planned |
1 |
|
|
|
2020-06-10 |
| A randomized, double-blind, placebo-controlled, phase II study to assess efficacy and safety of pamrevlumab versus standard of care in hospitalized patients with acute COVID-19 infection |
Coronavirus disease 19 infection |
pamrevlumab alone |
Connective tissue growth factor ligand inhibitor |
|
FibroGen Inc |
|
US |
|
|
|
Phase 2 Clinical |
Planned |
1 |
|
130 |
|
2020-06-10 |
| BOREA: An open-label, phase II/III, randomized, parallel-arm , investigator-initiated study to evaluate the efficacy and safety of pamrevlumab versus standard of care in patients with severe coronavirus 2019 (COVID-19) infection |
Coronavirus disease 19 infection |
pamrevlumab alone |
Connective tissue growth factor ligand inhibitor |
|
FibroGen Inc |
|
Italy |
2020-06-08 |
|
BOREA |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
|
68 |
Professor Luca Richeldi |
2020-06-10 |
| A clinical trial of AZD-1222 in the volunteers who have not previously contracted COVID-19 |
Coronavirus disease 19 infection |
AZD-1222 alone |
COVID19 Spike glycoprotein modulator |
|
Federal University of Sao Paulo |
The Lemann Foundation |
Brazil |
|
|
|
Phase Not Applicable |
Not yet recruiting |
1 |
|
2000 |
|
2020-06-10 |
| DiSurE-Covid19: Evaluation of COVID-19 Surveillance Programme in University Malaya Medical Center |
Coronavirus disease 19 infection |
|
|
|
University Malaya Medical Centre |
|
Malaysia |
2020-06-15 |
2022-08-31 |
55160, DiSurE-Covid19, NMRR-20-1097-55160 |
Phase Not Applicable |
Status not specified |
2 |
26 Months |
|
Diane Chong Woei Quan |
2020-06-11 |
| Acceptance and Perception of the COVID-19 vaccination in the general population of Malaysia |
Coronavirus disease 19 infection |
COVID-19 vaccination alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Institutes of Health Malaysia |
|
Malaysia |
2020-06-02 |
2020-11-30 |
55153, NMRR-20-1089-55153 |
Phase Not Applicable |
Not yet recruiting |
1 |
5 Months |
|
Dr June Lau Fei Wen |
2020-06-11 |
| A clinical study of camostat mesylate for the treatment of patients with COVID-19 infection |
Coronavirus disease 19 infection |
camostat mesylate alone |
Serine protease inhibitor, Transmembrane serine protease 2 inhibitor, Trypsin inhibitor |
|
Ono Pharmaceutical Co Ltd |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-06-10 |
| A clinical study on the safety of camostat mesilate in healthy volunteers |
Coronavirus disease 19 infection |
camostat mesylate alone |
Serine protease inhibitor, Transmembrane serine protease 2 inhibitor, Trypsin inhibitor |
Healthy volunteers accepted |
Ono Pharmaceutical Co Ltd |
|
|
2020-06-05 |
|
|
Phase Not Applicable |
Recruiting |
0 |
|
|
|
2020-06-10 |
| SUCCESS: Surveillance of SARS-CoV-2 Virus Antibody in Health Care and Close-Contact Workers |
Coronavirus disease 19 infection |
COVID-19 antibody laboratory test alone, COVID-19 antibody point-of-care test kit alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kinki Health Administration Center (KKC), Mie Health Checkup Clinic |
|
Japan |
2020-06-10 |
2021-07-31 |
SUCCESS, UMIN000040694 |
Phase Not Applicable |
Not yet recruiting |
1 |
13 Months |
1000 |
Masakatsu Nishikawa |
2020-06-10 |
| YOCO: Yoga Pranayama Adjuvant to Treat Burden COVID-19 |
Coronavirus disease 19 infection |
Morning pranayama alone, Pre dinner pranayama alone, Pre lunch pranayama alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Health Ricerca e Sviluppo Srl |
Casa di Riposo e Ambulatorio Giardino St Lucia, Massa Lomabarda (Ra) Italy, EJTN GEIE, Halnet Srl, Swami Vivekananda Yoga Anusandhana Samsthana Svyasa, Yoga Experience Association |
Italy |
2020-06-01 |
2021-09-30 |
2020-001731-28, 2020_COVID19_YOGA, NCT04413747, YOCO |
Phase Not Applicable |
Not yet recruiting |
1 |
16 Months |
1000 |
Boris Bazzani, ERYT, Enrico Ricci, MD, Giorgio Noera, MD, PhD, HR Nagendra., Eng, Luca Ghetti, Eng., Maria Donatella Barbagallo, MD, Maria Luisa Vitobello, Morena Gaddoni, Morena Gaddoni, MD, Nagarathna Raghuram, MD |
2020-06-10 |
| DEXDO-COVID: Immunomodulatory Profile of Dexmedetomidine Sedation in Patients Recovering After ARDS Covid-19 |
Adult respiratory distress syndrome, Coronavirus disease 19 infection, Immune disorder |
dexmedetomidine alone |
Alpha 2 adrenoceptor agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assistance Publique Hopitaux de Paris |
|
France |
2020-04-24 |
2021-02-28 |
2020-A00799-30, APHP200413, DEXDO-COVID, NCT04413864 |
Phase 2 Clinical |
Recruiting |
1 |
10 Months |
50 |
Alexandre Demoule, MD, PhD, Alexandre Demoule, Md, PhD, Alice JACQUENS, Vincent DEGOS, Pr |
2020-06-10 |
| Photodynamic Therapy for the Treatment of COVID-19 |
Coronavirus disease 19 infection |
Laser acupuncture alone, Methylene blue alone, photobiomodulation alone, photodynamic therapy alone |
|
|
Cairo University |
|
|
2020-08-31 |
2021-02-28 |
CU-NILES/16/20, NCT04416113 |
Phase Not Applicable |
Not yet recruiting |
0 |
6 Months |
60 |
Cairo University |
2020-06-12 |
| Assessment of N-95 Facemask for Use in COVID-19 Pandemic in Case of Shortage of Personal Protective Equipment |
Coronavirus disease 19 infection |
Assembled mask alone, Hans Rudolph mask naso-oral mask alone, Iso-Gard HEPA light Filter 28022 alone, RP Performax SE ELBOW alone, Respironics Performax Whole Face Mask alone, Teleflex Bacterial/Viral filter 1605 alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Oklahoma |
US Department of Veterans Affairs |
US |
2020-06-15 |
2025-05-31 |
11887, NCT04416919 |
Phase Not Applicable |
Not yet recruiting |
1 |
59 Months |
20 |
Ahel El Haj Chehade, MD, Houssein Youness, MD |
2020-06-11 |
| Evaluation of the effects of Oxycodone administration on pain control in patients with COVID-19 |
Coronavirus disease 19 infection, Dyspnea, Pain |
oxycodone alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shaheed Beheshti Medical University |
|
Iran |
2020-03-20 |
|
IR.SBMU.NRITLD.REC.1399.012, IRCT20150107020592N24 |
Phase 3 Clinical |
Recruiting |
1 |
|
60 |
Dr Mahmood Heydari, Dr Seyed Mohamadreza Hashemian, Seyed Mohammad Reza Hashemian |
2020-06-10 |
| A Clinical Study to Assess the Natural History of COVID-19 and Effects of KB109 and Supportive Self-care in Outpatients With Mild-to-moderate COVID-19 |
Coronavirus disease 19 infection |
KB-109 alone, Self Supportive Care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kaleido Biosciences Inc |
|
US |
2020-06-30 |
2020-12-31 |
K031-120, NCT04414124 |
Phase 2 Clinical |
Recruiting |
8 |
6 Months |
400 |
Mark Wingertzahn, PhD |
2020-06-11 |
| Clinical Trial On Mildly Symptomatic Covid -19 Patients And Health Care Workers Posted To Covid Wards |
Coronavirus disease 19 infection |
A Mulmina Mango alone, Mulmina Amla Orange alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Jagdale industries pvt Ltd |
|
India |
2020-06-15 |
|
CTRI/2020/06/025702, Protocol Version 1.0 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
80 |
Dr Ashok Godavarthi, Dr C R Jayanthi, Mr Raghavendra K V |
2020-06-11 |
| iCOVID19 Project: This study has been conducted to collect the Cough and breathing sound of COVID-19 positive and COVID-19 negative patients for analysis of early indication of COVID-19 in humans |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Imperial Clinical Research Services |
|
India |
2020-06-15 |
|
CTRI/2020/06/025675, iCOVID19 Project |
Phase Not Applicable |
Not yet recruiting |
1 |
|
600 |
Ajeet Nanda, Amlendu Yadav, Pragya Yadav |
2020-06-11 |
| O-CovAb: Oral Fluid Sars-CoV-2 Ab Rapid test |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Diabetes Research Society |
|
India |
2020-06-16 |
|
CTRI/2020/06/025674, O-CovAb |
Phase Not Applicable |
Not yet recruiting |
3 |
|
100 |
Prof N Partha Sarathy, Prof PV Rao, Prof V Chandrasekhar |
2020-06-11 |
| An off-label, prospective, observational study to assess the effect of acalabrutinib in patients with acute respiratory distress syndrome (ARDS) from COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
acalabrutinib alone |
Btk tyrosine kinase inhibitor |
|
AstraZeneca plc, US Oncology Inc |
National Cancer Institute, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Walter Reed Army Medical Center |
US |
|
|
|
Phase Not Applicable |
Status not specified |
3 |
|
19 |
|
2020-06-10 |
| Validating an ELISpot for Early Detection of an Active Immune Response Against COVID-19 |
Coronavirus disease 19 infection |
ELISpot alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire De Nice |
|
France |
2020-06-01 |
2021-06-01 |
20-PP-10, NCT04418206 |
Phase Not Applicable |
Not yet recruiting |
4 |
12 Months |
300 |
DUMON MARIE CHRISTINE, LEROUSSEAU LIONEL, LEROY SYLVIE, LEROY Sylvie, Leroy Sylvie, Rolland Fabien, griffonnet Jennifer, lerousseau lionel, rolland Fabien |
2020-06-11 |
| Investigation of the effects of prone position on cardiac and respiratory status in patients with coronavirus |
Coronavirus disease 19 infection, Respiratory disease |
prone position alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Lorestan University |
|
Iran |
2020-06-21 |
|
IR.LUMS.REC.1399.059, IRCT20160126026217N4 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
74 |
Ebrahim Falahi, Sajad Yarahmadi |
2020-06-11 |
| Prospective, cohort study of COVID-19 antibody for medical stuff in hospital |
Coronavirus disease 19 infection |
|
|
|
Gunma Prefectural Cancer Center |
|
Japan |
2020-06-08 |
|
UMIN000040679 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
50 |
Kazuhiro Araki |
2020-06-10 |
| Longitudinal study on work style change, health and well-being due to pandemic of novel coronavirus infection (COVID-19) |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Keio University |
Atrae Inc, Nittsu System Co Ltd |
Japan |
2020-06-08 |
|
20E0004, UMIN000040683 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
2000 |
Akihito Shimazu, Satoko Fujihara |
2020-06-10 |
| A global study of eritoran in hospitalized patients who tested positive with SARS-CoV-2 infection (COVID-19) |
Coronavirus disease 19 infection |
eritoran alone |
TLR-4 antagonist |
|
Eisai Co Ltd |
|
|
2020-06-30 |
|
|
Phase Not Applicable |
Planned |
0 |
|
400 |
|
2020-06-09 |
| A Phase II clinical trial of AQCH for potential treatment of COVID-19 |
Coronavirus disease 19 infection |
AQCH alone |
|
|
Sun Pharmaceutical Industries Ltd |
|
India |
|
|
|
Phase 2 Clinical |
Not yet recruiting |
1 |
|
210 |
|
2020-06-09 |
| Ulinastatin for COVID-19 in patients with breathlessness |
Coronavirus disease 19 infection, Respiratory distress syndrome |
Variable regimens including azithromycin , hydroxychloroquine , ulinastatin (sepsis/acute pancreatitis), Bharat Serums and Vaccines |
Trypsin inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Bharat Serums & Vaccines Ltd |
|
India |
2020-07-01 |
|
BSV_ULINA_20_03_IN, CTRI/2020/06/025704 |
Phase 3 Clinical |
Not yet recruiting |
6 |
|
120 |
Dr Amlendu Yaadav, Dr Apurva Agarwal, Dr Dibakar Sahu, Dr Harish Mallapura Maheshwarappa, Dr Madhusudan Jaju, Dr Rohidas Borse, Dr Shreepad Bhat, Dr Uday Harle |
2020-06-11 |
| Phase II study to evaluate the safety and efficacy of 2-Deoxy-D-Glucose in COVID-19 patients |
Coronavirus disease 19 infection |
2-deoxy-D-glucose alone, standard-of-care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Dr Reddy's Laboratories Ltd, Institute of Nuclear Medicine and Allied Sciences (INMAS) |
|
India |
2020-06-15 |
|
CTRI/2020/06/025664, CVD-19-CD-002, Version 2.0 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
40 |
D Mallikarjuna Rao, Dr Apurva Agarwal |
2020-06-10 |
| To Assess the Safety and Outcome of Herbal Medicine in Prevention of COVID-19 Infection Among High Risk Population |
Coronavirus disease 19 infection |
Variable regimens including behidana , khameera marwareed , oshanda , sapistan , unnab |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Ministry of Ayush |
|
India |
2020-06-15 |
|
CTRI/2020/06/025650 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
4000 |
Prof Abdul Wadud |
2020-06-10 |
| In vivo use of ivermectin (IVR) for treatment for corona virus infected patients: a randomized controlled trial |
Coronavirus disease 19 infection |
ivermectin alone |
Chloride channel modulator |
|
Rayak Hospital |
|
Lebanon, Iraq |
2020-06-10 |
2020-07-31 |
ChiCTR2000033627 |
Phase 0 Clinical |
Not yet recruiting |
2 |
1 Month |
60 |
Dr. Houssam RaaD, Mirna Fawaz |
2020-06-10 |
| A study on association between tobacco and COVID 19 to help policy makers |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Scottish Funding Council, University of Edinburgh |
|
India |
2020-06-15 |
|
COVID_IMPACT, CTRI/2020/06/025673 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
50 |
Muralidhar Kulkarni |
2020-06-10 |
| A medical records based study for nano short peptide nutrition intervention on the prognosis of patients with novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Nano short peptide enteral nutrition alone, whole protein enteral nutrition alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The First College Of Clinical Medical Science, China Three Gorges University |
|
China |
2020-05-07 |
2020-06-17 |
ChiCTR2000033609 |
Phase Not Applicable |
Not yet recruiting |
1 |
1 Month |
206 |
Ze-Lin Zhang |
2020-06-10 |
| Prophylactic study of outbreak of novel coronavirus in Indian scenario in Distric Hospital, Vidisha |
Coronavirus disease 19 infection |
piper betal plus swarnabhasma |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Government medical college, Bhopal |
|
India |
2020-06-22 |
|
CTRI/2020/06/025637 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
10 |
Dr Sarvesh Sharma |
2020-06-10 |
| Analysis of Characteristics of recurrent positive RT-PCR findings of recovered patients from novel coronavirus pneumonia (COVID-19) in Wuhan, China: a medical records based study |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
Yunnan Center for Disease Control and Prevention |
|
China |
2020-01-01 |
2020-03-20 |
ChiCTR2000033580 |
Phase Not Applicable |
Completed |
1 |
2 Months |
758 |
SHUI TIEJUN |
2020-06-10 |
| To evaluate the effect of herbal medicine in prevention and management of COVID-19 |
Coronavirus disease 19 infection |
Joshanda (Decoction) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Ministry of Ayush, National Institute of Unani Medicine |
|
India |
2020-06-15 |
|
CTRI/2020/06/025672 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
60 |
Dr Fasihur Rehman Ansari, Dr Mariyam Ahad, Dr Mohd Aleemuddin Quamri |
2020-06-10 |
| A clinical trial to evaluate the medicinal efficacy of Ayurvedic Tablet Bhoumya and Tablet Saathmya in COVID-19 positive Patients |
Coronavirus disease 19 infection, Viral pneumonia |
standard care alone, Bhoumya plus Saathmya |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Prashanthi Ayurvedic Centre |
|
India |
2020-06-15 |
|
CTRI/2020/06/025671 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
10 |
Dr C R Jayanthi, Dr Giridhara Kaje, Dr Harish M |
2020-06-10 |
| PREVENGHO-COVID: PrevengHo-Vir Homeoprophylaxis COVID-2019 |
Coronavirus disease 19 infection |
PrevengHo-Vir alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Instituto Pedro Kouri |
|
Cuba |
2020-04-29 |
2020-12-31 |
PREVENGHO-COVID, RPCEC00000312 |
Phase 1 Clinical |
Recruiting |
1 |
8 Months |
180 |
Carlos Eugenio Royo Lafita, Elsida Lucía Rey Robira, Johann Perdomo Delgado |
2020-06-10 |
| CIGB-258 at COVID-19 |
Coronavirus disease 19 infection |
CIGB-258 alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Center for Genetic Engineering and Biotechnology |
Instituto Pedro Kouri |
Cuba |
2020-03-31 |
2020-04-30 |
CIGB-258/2020, RPCEC00000313 |
Phase 2 Clinical |
No longer recruiting |
1 |
1 Month |
16 |
Daniel González, Maria Carmen Domínguez Horta, Rafael Venegas Rodriguez |
2020-06-15 |
| Convalescent Antibodies Infusion in COVID-19 Patients |
Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia |
anti-coronavirus antibody therapy alone, double-filtration plasmapheresis alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ospedale Papa Giovanni XXIII |
Aferetica Srl |
Italy |
2020-06-30 |
2020-09-30 |
DFPP COVID 19 EARLY, NCT04418531 |
Phase 2 Clinical |
Not yet recruiting |
6 |
3 Months |
10 |
Anna Falanga, MD, Annapaola Callegaro, MD, Claudio Farina, MD, Diego Curtò, MD, Federica Casiraghi, Ferdinando Luca Lorini, MD, Giuseppe Remuzzi, MD, Laura Castellani, Biol.Sci.D, Lorenzo Grazioli, MD, Luca Barcella, MD, Marina Marchetti, Biol.Sci.D, Marina Noris, Ch., Piero Luigi Ruggenenti, Piero Luigi Ruggenenti, MD, Roberto Cosentini, MD, Stefano Rota, MD |
2020-06-10 |
| Peri-Operative NLR in Emergency General Surgery During COVID-19 Pandemic |
Coronavirus disease 19 infection |
emergency general surgery alone |
|
Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Barking Havering & Redbridge University Hospitals Nhs Trust |
|
UK |
2020-03-23 |
2020-06-30 |
133196, NCT04419571 |
Phase Not Applicable |
No longer recruiting |
1 |
3 Months |
100 |
Nader Habib Bedwani |
2020-06-10 |
| Online Learning of Veterinary Anatomy During COVID-19 Pandemic |
Coronavirus disease 19 infection |
online survey alone, online veterinary anatomy learning alone |
|
Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
South Valley University |
|
Egypt |
2020-06-05 |
2020-07-05 |
2-2020, NCT04418284 |
Phase Not Applicable |
Recruiting |
1 |
1 Month |
400 |
Mohamed Mahdy |
2020-06-17 |
| Vocal Feature Analysis Algorithm |
Coronavirus disease 19 infection |
Vocal Feature Analysis (VFA) algorithm app (Soniphi) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Soniphi LLC |
UserWise |
US |
2020-06-30 |
2020-12-31 |
002 SONIPHI, NCT04418544 |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
400 |
Lauren Vitalie, BA, Matthew Sanderson, BS |
2020-06-08 |
| COVID-HOP: Establishment of a Biological Collection During COVID-19 Serological Screening in APHP Professionals |
Coronavirus disease 19 infection |
biological sampling alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assistance Publique Hopitaux de Paris |
Fondation Hôpitaux de Paris-Hôpitaux de France |
France |
2020-06-30 |
2022-03-31 |
2020-A01364-35, APHP200609, COVID-HOP, NCT04418375 |
Phase Not Applicable |
Not yet recruiting |
5 |
21 Months |
4000 |
Béatrice Dr PARFAIT, PhD, Bénédicte Dr SAWICKI, PhD, Marie Dr COURBEBAISSE, MD, PhD, Martine Dr LOUET, PhD, Nathalie Dr DEMORY, PhD, Solen Dr KERNEIS, PhD, Véronique Dr MAHE, PhD |
2020-06-12 |
| Effect of Dinvl on improving of clinical and paraclinical symptoms in patients with COVID-19 |
Coronavirus disease 19 infection |
Dinvl herbal medicine alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Zahravi drug company |
|
Iran |
2020-06-20 |
|
IR.TBZMED.REC.1399.135, IRCT20200518047497N2 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
80 |
Azizeh Farshbaf-Khalili, Javad Ahmadian Heris |
2020-06-09 |
| CONCOR-1: A Trial of Convalescent Plasma for Hospitalized Adults With Acute COVID-19 Respiratory Illness |
Coronavirus disease 19 infection, Respiratory disease |
Convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Weill Medical College of Cornell University |
Hamilton Health Sciences Corp |
US |
2020-06-30 |
2021-12-31 |
20-04021981, CONCOR-1, NCT04418518 |
Phase 3 Clinical |
Not yet recruiting |
2 |
18 Months |
1200 |
Celine Arar, Marshall Glesby, MD, Marshall Glesby, MD, PhD |
2020-06-10 |
| PPT-COVID: Patient Preference Trial for COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
chloroquine alone, hydroxychloroquine alone, azithromycin plus hydroxychloroquine |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Princesse Grace |
|
Monaco |
2020-04-06 |
2020-09-01 |
20-08, NCT04418193, PPT-COVID |
Phase Not Applicable |
Recruiting |
1 |
4 Months |
100 |
Atul PATHAK, MD PhD, Celine DUGOURD |
2020-06-10 |
| VIVALDI: COVID-19 in care homes |
Coronavirus disease 19 infection |
Baseline assessment and antibody testing alone, Intensive testing for infection (PCR and antibody) alone |
|
Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of London |
National Institute for Health Research (NIHR) |
UK |
2020-05-28 |
2021-11-30 |
CPMS 45953, IRAS 284545, ISRCTN14447421, VIVALDI |
Phase Not Applicable |
Recruiting |
2 |
18 Months |
|
Dr Maria Krutikov, Dr Shallcross |
2020-06-10 |
| Neuro-COVID: Neurological Complications of COVID-19 |
Coronavirus disease 19 infection, Neurological disease |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Zurich |
|
Switzerland |
2020-05-01 |
2022-05-30 |
NCT04418609, NEURO-COVID-19, Neuro-COVID |
Phase Not Applicable |
Recruiting |
1 |
24 Months |
30 |
Emanuela Keller, Prof. Dr. |
2020-06-09 |
| COVIDOB: COVID-19 and Obstetric Transmission |
Coronavirus disease 19 infection |
RT-PCR alone, antibody testing alone |
|
Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
University Hospitals Of Cleveland |
Case Western Reserve University, Cleveland Clinic Foundation, Cuyahoga County Board of Health, MetroHealth Medical Center |
US |
2020-04-28 |
2021-07-31 |
20200479, COVIDOB, NCT04418557 |
Phase Not Applicable |
Recruiting |
1 |
15 Months |
200 |
Rachel Pope, Rachel Pope, MD, MPH |
2020-06-10 |
| A Study of TL-895 With Standard Available Treatment Versus Standard Available Treatment for the Treatment of COVID-19 in Patients With Cancer |
Coronavirus disease 19 infection, Viral pneumonia |
TL-895 alone, standard available treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Telios Pharma, Inc |
|
|
2020-06-30 |
2021-07-31 |
NCT04419623, TL-895-202 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
0 |
13 Months |
146 |
John Mei |
2020-06-10 |
| Effect of bee products on COVID-19 |
Coronavirus disease 19 infection |
Variable regimens including N-chromosome royal jelly , honey , propolis |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shaheed Beheshti Medical University |
|
Iran |
2020-05-30 |
|
IR.SBMU.NRITLD.REC.1399.048, IRCT20200209046427N1 |
Phase Not Applicable |
Recruiting |
1 |
|
60 |
Afshin Zarghi, Shadi Shafaghi |
2020-06-15 |
| CORDA: Covid Radiographic Images Data-set for AI |
Coronavirus disease 19 infection, Viral pneumonia |
chest x-ray radiography alone, neural network algorithm diagnosis alone |
|
|
Azienda Ospedaliera Citta della Salute e della Scienza di Torino |
Azienda Ospedaliera Ordine Mauriziano di Torino, University of Turin |
Italy |
2020-03-24 |
2021-03-31 |
CORDA, CORDA, NCT04419545 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
2500 |
Andrea Ferraris, M.D., Claudio Berzovini, M.D., Francesca Santinelli, M.Sc., Giorgio Limerutti, M.D., Marco Calandri, M.D., Marco Grosso, M.Sc., Paolo Fonio, M.D., Patrizia Sardo, M.D., Simona Capello, M.D., Stefano Tibaldi, M.Sc. |
2020-06-10 |
| COVID-US: Confirmation of Ventilation and Intubation by Determination With Ultrasonography |
Coronavirus disease 19 infection |
lung ultrasonography alone, tracheal ultrasonography alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Pittsburgh |
Baylor College of Medicine, Cleveland Clinic Foundation, Kadlec Regional Medical Center, Oregon Health Sciences University |
US |
2019-01-01 |
2020-05-30 |
COVID-US, NCT04419064, STUDY20050011 |
Phase Not Applicable |
Completed |
4 |
16 Months |
118 |
Mourad H Senussi, MD, MS |
2020-06-09 |
| A phase I clinical study of EXG-5003 for the potential treatment of COVID-19 |
Coronavirus disease 19 infection |
EXG-5003 alone |
COVID19 Spike glycoprotein modulator |
|
Elixirgen Therapeutics Inc |
|
US |
|
|
|
Phase 1 Clinical |
Planned |
1 |
|
|
|
2020-06-11 |
| A clinical study to assess QuadraMune in the treatment of patients suffering from COVID-19 and/or individuals at risk of COVID-19 |
Coronavirus disease 19 infection |
QuadraMune alone |
|
|
Therapeutics Solutions International Inc |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-06-08 |
| A pilot clinical feasibility study to assess QuadraMune in healthy subjects in the prevention of COVID-19 |
Coronavirus disease 19 infection |
QuadraMune alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Therapeutics Solutions International Inc |
|
|
|
|
|
Phase 1 Clinical |
Status not specified |
0 |
|
32 |
|
2020-06-08 |
| RAS and Coagulopathy in COVID-19 |
Blood clotting disorder, Coronavirus disease 19 infection |
TRV-027 alone |
Angiotensin II AT-1 receptor antagonist, Beta-arrestin stimulator |
Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Imperial College London |
|
UK |
2020-07-31 |
2021-01-31 |
283093, NCT04419610 |
Phase 0 Clinical |
Not yet recruiting |
1 |
6 Months |
60 |
DAVID OWEN, David Owen, Katrina Pollock, Lisa Hurley |
2020-06-18 |
| Living With Sickle Cell Disease in the COVID-19 Pandemic |
Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Sickle cell anemia, Sleep disorder |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Human Genome Research Institute |
National Institutes of Health Clinical Center |
US |
2020-06-22 |
2024-12-31 |
20-HG-N125, 999920125, NCT04417673 |
Phase Not Applicable |
Not yet recruiting |
1 |
54 Months |
700 |
Nathan Jones, Vence L Bonham, J.D. |
2020-06-18 |
| Retrospective examination of the course of a Covid-19 infection in patients with inflammatory bowel disease |
Coronavirus disease 19 infection, Inflammatory bowel disease |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
CSG - Clinische Studien Gesellschaft GmbH |
|
Germany |
2020-04-21 |
|
2020-1705-Reg, DRKS00021653 |
Phase Not Applicable |
Recruiting |
1 |
|
500 |
Niels Teich |
2020-06-08 |
| COVID-PraxImmun: Investigation of the immune status against SARS-CoV-2 of medical professionals in Doctor's Practices in Thuringia (COVID-19 research project) |
Coronavirus disease 19 infection |
Lateral-Flow-Assay IgM/IgG alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), European Ancestry |
Association of Statutory Health Insurance Physicians North Rhine |
Zentralinstitut für die kassenärztliche Versorgung in der Bundesrepublik Deutschland |
Germany |
2020-06-30 |
|
22860/2020/57, COVID-PraxImmun, DRKS00021815 |
Phase 4 Clinical |
Not yet recruiting |
1 |
|
10000 |
Anke Möckel, Thomas Schröter |
2020-06-08 |
| COVIDLight: Vielight RX Plus for the Treatment of COVID-19 Respiratory Symptoms |
Coronavirus disease 19 infection, Respiratory disease |
Vielight RX Plus alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Vielight Inc. |
|
Canada |
2020-07-01 |
2021-01-01 |
COVIDLight, NCT04418505, VL-2020-02 |
Phase Not Applicable |
Not yet recruiting |
1 |
6 Months |
280 |
Andrea Berk, Roy Tingley, MD |
2020-06-10 |
| COVID 19-IA: CT Biomarkers Identification by Artificial Intelligence for COVID-19 Prognosis |
Coronavirus disease 19 infection, Lung injury |
deep learning artificial intelligence alone, thoracic computed tomography scan alone |
|
|
Centre Hospitalier Universitaire de Nimes |
|
France, Martinique |
2020-03-01 |
2020-07-31 |
COVID 19-IA, NCT04418245, NIMAO/2020/COVID 19-IA/JF-01 |
Phase Not Applicable |
No longer recruiting |
6 |
5 Months |
1000 |
Julien Frandon |
2020-06-10 |
| Clinical Efficacy of Nafamostat Mesylate for COVID-19 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
antibiotic agents therapy alone, continuous renal replacement therapy (CRRT) alone, extracorporeal membrane oxygenation (ECMO) alone, hemodialysis (HD) alone, invasive ventilation therapy alone, non-invasive ventilation therapy alone, supplemental oxygen theray alone, Variable regimens including hydroxychlorquine , lopinavir + ritonavir , nafamostat mesylate |
HIV protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Gyeongsang National University Hospital |
|
South Korea |
2020-06-10 |
2021-04-30 |
2020-04-012, NCT04418128 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
10 Months |
84 |
IN-GYU BAE, MD, Kyunglan Moon, MD |
2020-06-11 |
| Efficacy of N-Acetylcysteine (NAC) in Preventing COVID-19 From Progressing to Severe Disease |
Coronavirus disease 19 infection |
N-acetylcysteine alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cambridge Health Alliance |
|
US |
2020-06-15 |
2021-03-31 |
CHA-IRB-1139/05/20, NCT04419025 |
Phase 4 Clinical |
Not yet recruiting |
1 |
9 Months |
200 |
Duncan Kuhn, MD, Melisa Lai-Becker, Melisa Lai-Becker, MD |
2020-06-10 |
| A phase I clincal study to test the efficacy of Carragelose for the trearment of viral pneumonia, SARS-CoV-2 and other viruses of the respiratory tract |
Coronavirus disease 19 infection, Respiratory tract infection, Viral pneumonia |
Carragelose alone |
|
|
Marinomed Biotechnologie GmbH |
|
|
|
|
|
Phase 1 Clinical |
Planned |
0 |
|
|
|
2020-06-09 |
| Effect of Umifenovir in treatment of covid-19 |
Coronavirus disease 19 infection |
Arbidol plus hydroxychloroquine |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tehran University of Medical Sciences |
|
Iran |
2020-04-20 |
2020-05-25 |
IR.TUMS.VCR.REC.1399.204, IRCT20200523047550N1 |
Phase 3 Clinical |
Completed |
1 |
1 Month |
50 |
Sara Ghaderkhani |
2020-06-09 |
| A clinical trial of pritumumab for the potential treatment of COVID-19 infection |
Coronavirus disease 19 infection |
pritumumab alone |
Vimentin modulator |
|
Nascent Biotech Inc |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-06-08 |
| Difficulty in doing usual work after wearing personal protective equipment |
Coronavirus disease 19 infection |
Personal Protective Equipment alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
All India Institute of Medical Sciences |
|
India |
2020-06-04 |
|
CTRI/2020/06/025560 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
50 |
Dr Puneet Khanna |
2020-06-08 |
| Homoeopathic Medicines Bryonia alba 30C as a Prophylaxis for COVID-19 |
Coronavirus disease 19 infection |
Bryonia alba alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Principal Aarogya Homoeopathic Medical College and Hospital |
Ministry of Ayush |
India |
2020-06-15 |
|
CTRI/2020/06/025558 |
Phase 4 Clinical |
Not yet recruiting |
1 |
|
300 |
Dr Dan Singh Meena, Prof Dr Puneet R Shah |
2020-06-09 |
| DAWN AntiCo: A randomized, open-label, adaptive, proof-of-concept clinical trial of modulation of host thromboinflammatory response in patients with COVID-19 |
Coronavirus disease 19 infection |
Aprotinin alone, anakinra alone, enoxaparin sodium alone, nadroparin calcium alone |
Low molecular weight heparin, Type I IL-1 receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
UZ Leuven-University Hospitals |
|
Belgium |
2020-05-20 |
|
2020-001739-28, DAWN AntiCo, S63979 |
Phase 2 Clinical |
Recruiting |
1 |
|
|
Caroline Devooght |
2020-06-08 |
| COVID-PREVENT: Effect of Anticoagulation Therapy on Clinical Outcomes in COVID-19 |
Arterial thrombosis, Coronary artery disease, Coronavirus disease 19 infection, Deep vein thrombosis, Diabetes mellitus, Lung embolism, Myocardial infarction, Nicotine dependence, Stroke, Thromboembolism |
rivaroxaban alone |
Factor Xa antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Charite University |
Bayer AG, Deutsches Zentrum für Herz-Kreislauf-Forschung |
Germany |
2020-06-15 |
2021-05-30 |
2020-002282-33, COVID-PREVENT, COVID-PREVENT, NCT04416048 |
Phase 3 Clinical |
Not yet recruiting |
27 |
11 Months |
400 |
Andreas Zeiher, Prof. Dr., Aviva Raatz, Dr., Burkhard Pieske, Prof. Dr., Carsten Büning, Prof. Dr., Christiane Erley, Prof. Dr., Christoph Stellbrink, Prof. Dr., Co-PI: Andreas M. Zeiher, Prof. Dr., Co-PI: Steffen Massberg, Prof. Dr., Co-PI: Ursula Rauch-Kröhnert, Prof. Dr., Dennis Wolf, PD Dr., Fabrizio Esposito, Dr., Hans-Christian Mochmann, Dr., Hans-Heinrich Minden, Dr., Ingo Eitel, Prof. Dr., Jakob Ledwoch, Dr., Jan Beyer-Westenhoff, PD Dr., Jan Cornely, Kurt Rasche, Prof. Dr., Leonhard Bruch, Dr., Martin Witzenrath, Prof. Dr., Olaf Göing, Dr., Sebastian Schellong, Prof. Dr., Stefan Felix, Prof. Dr., Steffen Behrens, Prof. Dr., Steffen Massberg, Prof. Dr., Steffen Schön, Prof. Dr., Thomas Münzel, Prof. Dr., Tim Seidler, Prof. Dr. med., Timm Westhoff, Prof. Dr., Ulf Landmesser, Prof. Dr., Ursula Rauch-Kroehnert, Prof. Dr. med., Uta Merle, Prof. Dr. |
2020-06-08 |
| COACHING FOR COVID-19: A Pilot Study Investigating the Effectiveness of Coaching on Psychological Outcomes in Hospital-Based Senior Doctors |
Acute stress disorder, Coronavirus disease 19 infection |
coaching sessions alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
South Western Sydney Local Health Network |
Liverpool Hospital |
Australia |
2020-06-05 |
|
ACTRN12620000636954p |
Phase Not Applicable |
Not yet recruiting |
1 |
|
35 |
A/Prof Samuel Harvey, Dr Sarah Dalton, Ms Rita Holland |
2020-06-14 |
| Testing an Online Coping Skills Intervention for People Living with Chronic Illness During the COVID-19 Pandemic |
Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression |
follow-up questionnaire alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Auckland |
|
New Zealand |
2020-06-08 |
|
ACTRN12620000634976p, U1111-1252-5637 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
46 |
Dr Anna Serlachius |
2020-06-08 |
| INFLAMMACOV: An open, prospective, randomized, therapeutic trial using anakinra or tocilizumab alone or in association with ruxolitinib in severe stage 2b and 3 COVID-19-associated Disease |
Coronavirus disease 19 infection, Hypoxia, Respiratory distress syndrome, Viral pneumonia |
anakinra alone, tocilizumab (intravenous), Roche/Chugai alone, Variable regimens including anakinra , ruxolitinib , tocilizumab (intravenous), Roche/Chugai |
IL-6 receptor antagonist, IL-6 receptor modulator, Jak1 tyrosine kinase inhibitor, Jak2 tyrosine kinase inhibitor, Type I IL-1 receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Assistance Publique Hopitaux De Marseille |
|
France |
2020-09-01 |
2022-11-01 |
2020-001754-21, 2020-23, INFLAMMACOV, NCT04424056 |
Phase 3 Clinical |
Not yet recruiting |
2 |
26 Months |
216 |
Gilles Kaplanski, Gilles Kaplanski, MD |
2020-06-10 |
| A Study of Opaganib in Coronavirus Disease 2019 Pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
opaganib alone, standard of care alone |
Dihydroceramide delta 4 desaturase inhibitor, Sphingosine kinase 2 inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
RedHill Biopharma Ltd |
|
US |
2020-06-11 |
2020-12-31 |
ABC-110, NCT04414618 |
Phase 2a Clinical |
Recruiting |
2 |
6 Months |
40 |
Kevin Winthrop, MD, MPH, Mark L Levitt, MD, PhD, Vered Katz Ben-Yair, MSc |
2020-06-15 |
| SAVE-ICU: Sedating With Volatile Anesthetics Critically Ill COVID-19 Patients in ICU: Effects On Ventilatory Parameters And Survival |
Anesthesia, Coronavirus disease 19 infection |
isoflurane alone, sevoflurane alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sunnybrook Health Sciences Centre |
|
Canada |
2020-06-15 |
2022-06-15 |
2149, NCT04415060, SAVE-ICU |
Phase 3 Clinical |
Not yet recruiting |
2 |
24 Months |
752 |
Angela Jerath, MD, Brian Cuthbertson, MD, Claudio Martin, MD, Marat Slessarav, MD, Marat Slessarev, MD |
2020-06-12 |
| Hydroxychloroquine to Prevent SARS-CoV-2 Infection |
Coronavirus disease 19 infection |
hydroxychloroquine alone, standard personal protection measure alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universidad Peruana Cayetano Heredia |
|
Peru |
2020-06-30 |
2020-10-31 |
202087, 20923, NCT04414241 |
Phase 3 Clinical |
Not yet recruiting |
4 |
4 Months |
320 |
Aldo Lucchetti, MD, Alejandro Llanos, MD, PhD, Alonso Soto, MD, MSc, PhD, Alvaro Schwalb, MD, César Ugarte-Gil, MD, MSc, PhD, Eduardo Gotuzzo, MD, Fernando Mejia, MD, MSc, Manuel Espinoza, MD, Max Grogl, PhD, Patricia García, MD, MPH, PhD, Rosio Guerra, MD, MPH |
2020-06-08 |
| Effects of a N95 Respirator versus Cloth Mask on Exercise Capacity During Treadmill Exercise |
Coronavirus disease 19 infection |
Cloth Face Mask alone, Modified Balke Treadmill test alone, N-95 Respirator alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cleveland Clinic Foundation |
|
US |
2020-06-01 |
2020-08-01 |
20-538, NCT04415879 |
Phase Not Applicable |
Recruiting |
2 |
2 Months |
20 |
Debasis Sahoo, Matthew Kampert |
2020-06-10 |
| COVID19 Clinical Predictors and Outcome |
Coronavirus disease 19 infection, Respiratory failure |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
St George's University Hospitals NHS Foundation Trust |
St Georges University of London |
UK |
2020-06-15 |
2022-04-30 |
2020.0115, NCT04416347 |
Phase Not Applicable |
Not yet recruiting |
1 |
22 Months |
800 |
Timothy D Planche, Dr. |
2020-06-08 |
| PROTECT-COVID-19: Conestat Alfa in the Prevention of Severe SARS-CoV-2 Infection in Hospitalized Patients With COVID-19 |
Acute lung injury, Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia |
conestat alfa alone, standard of care alone |
Complement C1s subcomponent inhibitor, Kallikrein modulator, Mannan-binding lectin serine protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Pharming Group NV, University Hospital Basel |
Pharming Technologies BV |
Switzerland |
2020-06-30 |
2021-07-31 |
2020-01252, ME20OSTHOFF3, NCT04414631, PROTECT-COVID-19 |
Phase 2 Clinical |
Not yet recruiting |
1 |
13 Months |
120 |
Marten Trendelenburg, Prof. med, Michael Osthoff, PD Dr. med, Michael Osthoff, PD Dr. med., Parham Sendi, Prof. med., Stephan Moser, MD |
2020-06-08 |
| Mesenchymal Stem Cell for Acute Respiratory Distress Syndrome Due for COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia |
mesenchymal stem cells alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Instituto Nac De Ciencias Medicas Y Nutricion Salvador Zubiran |
|
Mexico |
2020-05-01 |
2021-05-01 |
NCT04416139, SCI-3354-20-21-1 |
Phase 2 Clinical |
Recruiting |
1 |
12 Months |
10 |
Carlos A Aguilar-Salinas, MD, Carlos Aguilar-Salinas, MD, Martin Iglesias, MD |
2020-06-08 |
| USZ BioResource COVID |
Coronavirus disease 19 infection |
blood sampling for biobank alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Zurich |
|
Switzerland |
2020-04-09 |
2022-04-30 |
CTC HFV2, NCT04414657 |
Phase Not Applicable |
Recruiting |
1 |
24 Months |
500 |
Anja Eskat, PhD, Regina Grossmann, Dr med, Silke Ludwig, MSc |
2020-06-08 |
| COVID-19: The Role of a Private Hospital in Hong Kong Amid COVID-19 Pandemic |
Coronavirus disease 19 infection |
COVID-19 diagnostic test alone |
|
|
Hong Kong Sanatorium & Hospital |
|
Hong Kong |
2020-05-25 |
2020-08-31 |
COVID-19, NCT04416061, RC-2020-08 |
Phase Not Applicable |
No longer recruiting |
1 |
3 Months |
2500 |
Jonpaul Sze Tsing Zee, MBChB |
2020-06-08 |
| ERSul study: Sulodexide in the treatment of COVID-19 |
Coronavirus disease 19 infection |
conventional treatment alone, sulodexide alone |
Heparin agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
CLINEDEM, Mexico |
Alfasigma SpA |
Mexico |
2020-04-15 |
2020-11-30 |
ERSul study, ISRCTN59048638 |
Phase 4 Clinical |
Not yet recruiting |
1 |
7 Months |
600 |
Dr Alejandro Jose Gonzalez Ochoa |
2020-06-08 |
| Evaluation of chloroquine blood levels |
Coronavirus disease 19 infection, Plasmodium vivax infection |
chloroquine alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Fundacao Oswaldo Cruz (Fiocruz) |
|
Brazil |
2017-05-08 |
2017-05-08 |
2.044.073, CAAE 67860317.3.0000.5409, RBR-6mjqrf, U1111-1252-6561 |
Phase 1/Phase 2 Clinical |
Completed |
1 |
|
32 |
Douglas Pinto |
2020-06-09 |
| COOPCOVID-19: Treatment of Patients With COVID-19 With Convalescent Plasma |
Coronavirus disease 19 infection |
convalescent plasma alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo |
Faculdade de Ciências Aplicadas (FCA) da UNICAMP, Fundacao Hemocentro de Ribeirao Preto, Hospital Of Syrian Lebanese Itatiba S/C Ltd, Ministry of Science and Technology, Brazil, Sociedade Beneficente Israelita Brasileira Hospital Albert Einsten |
Brazil |
2020-06-01 |
2022-05-22 |
COOP-COVID-19-MCTIC, COOPCOVID-19, NCT04415086 |
Phase 2 Clinical |
Recruiting |
1 |
23 Months |
120 |
Denivalda SG Araujo, Esper G Kallas, PhD MD, Esper G Kallás, PhD, MD, Natália B Cerqueira, Zelinda B Nakagawa, MsC, Zelinda Maria B Nakagawa |
2020-06-10 |
| ReCOVER: Evaluation of a Remote Monitoring Smartphone Application and Care Model of COVID-19 Patients in the Community (ReCOVER) |
Coronavirus disease 19 infection |
TCC-COVID mHealth solution alone, standard of care treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of New South Wales |
Health South Eastern Sydney Local Health District, The George Institute for International Health |
Australia |
2020-05-20 |
2021-05-19 |
NCT04399109, PID00770, ReCOVER |
Phase Not Applicable |
Recruiting |
3 |
12 Months |
2000 |
Benjamin Kwan, Clarissa Susanto, Dr Sze-Yuan Ooi, Jeffrey Post, Kristen Overton, Nigel Lovell, Pamela Konecny, Richard Sullivan, Sze-Yuan Ooi |
2020-06-09 |
| Short-term Physical Function Outcomes in Severe COVID-19 Patients Admitted to ICU for Invasive Mechanical Ventilation |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal |
|
Spain |
2020-05-15 |
2020-11-15 |
165/20, NCT04400461 |
Phase Not Applicable |
Recruiting |
2 |
6 Months |
50 |
Irene Lázaro Navarro, PT,MSc,PhD, Luís López-Gónzalez, PT, MSc, Maria Natividad Seisdedos-Nunez, PT, MSc, María-Natividad Seisdedos-Nunez, PT, MSc |
2020-06-09 |
| COVRTE-19: Low Dose Pulmonary Irradiation in Patients With COVID-19 Infection of Bad Prognosis |
Coronavirus disease 19 infection, Respiratory disease, Viral pneumonia |
low dose lung radiotherapy alone, standard support therapy alone |
|
Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fundacion Hospital Provincial de Castellon |
|
Spain |
2020-06-01 |
2021-03-31 |
COVRTE-19, FHPCS-20-001, NCT04414293 |
Phase 2 Clinical |
Not yet recruiting |
1 |
10 Months |
41 |
Carlos Ferrer Albiach, MD, Francisco Garcia Piñón, MSc |
2020-06-10 |
| EIKOS: Exploring immunological control mechanisms of SARS-CoV-2 (COVID-19) |
Coronavirus disease 19 infection |
ELISA alone, Neutralization assay alone, cytokine release assay alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital of Cologne |
Deutsches Zentrum für Infektionsforschung |
Germany |
2020-06-05 |
|
20-1187, DRKS00021468, EIKOS |
Phase Not Applicable |
Not yet recruiting |
1 |
|
2000 |
Florian Klein, Henning Grüll |
2020-06-06 |
| Quality of life in COVID-19 survivors |
Anxiety disorder, Coronavirus disease 19 infection, Depression, Fatigue, Post traumatic stress disorder |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Center for Integrated Rehabilitation and Organ Failure Horn |
|
Netherlands |
2020-05-07 |
2021-06-01 |
NL8587 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
500 |
Martijn Spruit |
2020-06-09 |
| BCG-PLUS: Enhancing the BCG-induced trained immunity response by addition of bisphosphonate or MMR vaccine: a possible preventive approach against COVID-19 |
Coronavirus disease 19 infection |
BCG alone, MMR alone, Variable regimens including BCG , MMR , bisphosphonate |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Radboud University |
Netherlands Organisation for Scientific Research |
Netherlands |
2020-05-25 |
2020-06-08 |
BCG-PLUS, NL8609 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
100 |
Priya Debisarun |
2020-06-09 |
| Oral Favipiravir for Patients with Delayed SARS-Cov-2 viral RNA Clearance |
Coronavirus disease 19 infection, Viral infection |
favipiravir alone |
RNA polymerase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Wuhan Huoshenshan Hospital |
|
China |
2020-03-18 |
2020-05-12 |
ChiCTR2000033491 |
Phase 4 Clinical |
No longer recruiting |
1 |
1 Month |
9 |
Jiqiu Wen |
2020-06-08 |
| A Phase II Study to Evaluate Axatilimab for Hospitalized Patients With Respiratory Involvement Secondary to COVID-19 |
Coronavirus disease 19 infection, Respiratory disease |
Standard of care alone, axatilimab alone |
CSF-1 antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Syndax Pharmaceuticals Inc |
|
US |
2020-05-30 |
2020-11-15 |
NCT04415073, SNDX-6352-0505 |
Phase 2 Clinical |
Recruiting |
2 |
5 Months |
186 |
Magdalena Mamczur-Madry, RN, BSN, MS, ACRP-CP, Michael S. Gordon, M.D., Shani Hilliard, Sue Fischer |
2020-06-08 |
| ESHAZ: Hydroxychloroquine, Azithromycin and Zinc for the treatment of SARS-Cov2 infection in Senegal. COVID-19 |
Coronavirus disease 19 infection |
azithromycin plus hydroxychloroquine |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cheikh Anta Diop University |
|
Senegal |
2020-06-01 |
|
ESHAZ, PACTR202005622389003 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
384 |
Cheikh T. NDOUR, Roger TINE |
2020-06-08 |
| RESOLUTION: Study of LAU-7b for the Treatment of COVID-19 Disease in Adults |
Coronavirus disease 19 infection, Lung inflammation, Respiratory distress syndrome |
fenretinide (pulmonary Pseudomonas aeruginosa infections in cystic fibrosis), McGill University/Laurent Pharmaceuticals alone, standard-of-care alone |
Nuclear factor kappa B gene modulator |
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Laurent Pharmaceuticals |
|
Canada, US |
2020-06-15 |
2021-01-15 |
LAU-20-01, NCT04417257, RESOLUTION |
Phase 2 Clinical |
Not yet recruiting |
7 |
7 Months |
300 |
Alexandria Flannery, Christian Allard, MD, Danae Tassy, PhD, François Marquis, MD, François Tremblay, MD FRCPC, Guillaume Coté-Maurais, MSc, Jean-Marie Houle, PhD, John Boyd, MD FRCPC, Mylene Roy, Nadia Beaudoin, MSc RRT, Nancy-Lisa Gagné, Radu Pislariu, MD, Ramy Saleh, MD, Sébastien Poulin, MD, Todd Campbell Lee, MD, Vanessa Larouche, Yannick Sardin Laframboise |
2020-06-17 |
| ECHO-COVID: Echocardiography in Critically-ill Patients With COVID-19 Pneumonia |
Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia |
echocardiography alone |
|
|
Hôpital Ambroise Paré |
|
France |
2020-05-12 |
2020-09-30 |
ECHO-COVID, NCT04414410, REDCAP19 |
Phase Not Applicable |
Recruiting |
1 |
4 Months |
1500 |
Antoine Vieillard-Baron, MD, PhD |
2020-06-08 |
| MODERATE I-TOMIC: Tofacitinib for Treatment of Moderate COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
standard of care alone, tofacitinib alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Yale University |
|
US |
2020-06-30 |
2021-03-31 |
2000027848, MODERATE I-TOMIC, NCT04415151 |
Phase 2b Clinical |
Not yet recruiting |
1 |
9 Months |
60 |
Hyung Chun, MD, Kelly Borges, MS, BS |
2020-06-08 |
| Extracellular Water in Covid-19 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
whole body bioimpedence system (NİCaS) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Gaziosmanpasa Taksim Research and Education Hospital |
|
Turkey |
2020-07-05 |
2021-02-20 |
76, NCT04416009 |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
52 |
SİBEL BEKTAŞ, aygen türkmen, Prof.MD, zuhal çavuş, MD |
2020-06-08 |
| AntiCoV-HB: COVID-19: Seroprevalence Study of Anti SRAS-CoV-2 Antibodies in GHT Employees in Haute Bretagne |
Coronavirus disease 19 infection |
NG-Biotech test alone, blood test alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Rennes University Hospital |
Fonds Nominoë |
France |
2020-05-29 |
2020-11-10 |
35RC20-9716, AntiCoV-HB, NCT04416308 |
Phase Not Applicable |
Recruiting |
1 |
5 Months |
13000 |
Agnès GAZZOLA, CHRISTOPHE PARIS, MD, Christophe PARIS, MD, RONAN GARLANTEZEC, MD, Ronan GARLANTEZEC, MD |
2020-06-08 |
| HoCoPsy: Characteristics of the Patients Hospitalized With Involuntary Commitment Procedure, in the Context COVID-19 |
Coronavirus disease 19 infection, Psychiatric disorder |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital, Montpellier |
|
France |
2020-05-01 |
2020-06-30 |
HoCoPsy, NCT04417374, RECHMPL20_0320 |
Phase Not Applicable |
No longer recruiting |
1 |
2 Months |
94 |
Emilie Olie, MD PhD |
2020-06-06 |
| COVILLE2: Part 2 on the Study Prevalence of SARS -Cov2 Carriage in Asymptomatic and Mildly-symptomatic Children |
Coronavirus disease 19 infection |
RT-PCR alone, Sars-Cov2 serology alone |
|
Healthy volunteers accepted, Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) |
Centre Hospitalier Intercommunal Creteil |
ACTIV, France, GFRUP, GPIP (FR) |
|
2020-06-07 |
2020-11-15 |
COVILLE2, COVILLE2, NCT04416893 |
Phase Not Applicable |
Not yet recruiting |
0 |
5 Months |
630 |
|
2020-06-08 |
| Who Benefits More? Optimizing Mindfulness Based Interventions for Improved Psychological Outcomes |
Acute stress disorder, Coronavirus disease 19 infection, Sleep disorder |
mindfulness based intervention alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National University of Singapore |
Brahm Centre |
Singapore |
2019-09-20 |
2022-06-30 |
NCT04417153, S-19-176 |
Phase Not Applicable |
Recruiting |
1 |
33 Months |
1000 |
Francesca Perini, PhD, Julian Lim, PhD |
2020-06-10 |
| ILIAD 7: Recombinant InterLeukin-7 (CYT107) to Improve clinical outcomes in lymphopenic pAtients with COVID-19 infection |
Coronavirus disease 19 infection, Lymphocytopenia |
CYT-107 alone |
IL-7 receptor agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Revimmune Inc |
|
France |
2020-05-06 |
|
2020-001573-78, 87RI20_0012, ILIAD 7 |
Phase 2 Clinical |
Recruiting |
1 |
|
200 |
Renaud MARTIN |
2020-06-06 |
| Melatonin Immune Boost COVID 19 Study |
Coronavirus disease 19 infection |
melatonin alone |
|
Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
All India Institute Of Medical Sciences, Rishikesh |
|
India |
2020-06-15 |
|
CTRI/2020/06/025613 |
Phase 4 Clinical |
Not yet recruiting |
1 |
|
200 |
Rohit Walia |
2020-06-08 |
| COVIM: COVID-19 Epidemic and Patients With Myeloproliferative Neoplasias |
Coronavirus disease 19 infection, Myelofibrosis, Myeloproliferative disorder, Polycythemia vera, Thrombocythemia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
French Innovative Leukemia Organisation |
|
France |
2020-06-15 |
2020-12-31 |
COVIM, COVIM, NCT04416438 |
Phase Not Applicable |
Not yet recruiting |
2 |
6 Months |
50 |
Jean-Jacques KILADJIAN, Pr, Laurence LEGROS, Dr, Valerie ROLLAND |
2020-06-08 |
| A trial to evaluate replication-competent VSV chimeric virus-based vaccine (COVID-19), IAVI/Batavia Biosciences/Merck & Co Inc for the prevention of SARS-CoV-2 infection |
Coronavirus disease 19 infection |
replication-competent VSV chimeric virus-based vaccine (COVID-19), IAVI/Batavia Biosciences/Merck & Co Inc alone |
COVID19 Spike glycoprotein modulator |
|
International AIDS Vaccine Initiative |
Merck & Co Inc |
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-06-05 |
| An observational, retropsective, single-center study to evaluate the short-term effect of risk-adapted treatment strategy on patients with COVID-19 |
Coronavirus disease 19 infection |
|
|
|
Chinese Academy of Sciences, University of Science & Technology of China |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
55 |
|
2020-06-10 |
| RE-HCP2 COVID study: A study to determine relative efficacy of hydroxychloroquine prophylaxis to healthcare-professionals for Covid-19 mitigation |
Coronavirus disease 19 infection |
hydroxychloroquine alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
All India Institute Of Medical Sciences, Rishikesh |
|
India |
2020-06-12 |
|
CTRI/2020/06/025593, RE-HCP2 COVID study |
Phase Not Applicable |
Not yet recruiting |
1 |
|
3000 |
Prasan Kumar Panda |
2020-06-08 |
| CovILD: Development of Interstitial Lung Disease (ILD) in Patients With Severe SARS-CoV-2 Infection (COVID-19) |
Coronavirus disease 19 infection, Interstitial lung disease |
Blood sampling alone, HRCT alone, Spirometry alone, echocardiography alone, plethysmography alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Medizinische Universität Innsbruck |
|
Austria |
2020-04-29 |
2022-04-28 |
20200429-2255, CovILD, NCT04416100 |
Phase Not Applicable |
Recruiting |
1 |
24 Months |
130 |
Ivan Tancevski, Doz. Dr., Judith Löffler-Ragg, Prof. Dr. |
2020-06-08 |
| Quality of Life and Patient-centered Outcomes After ICU Admission for COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Porto |
Centro Hospitalar De São João, E.P.E., Centro Hospitalar Lisboa Ocidental, Centro Hospitalar do Porto, Universidade Do Algarve |
Portugal |
2020-06-15 |
2022-10-01 |
NCT04416464, QOL_ICU_COVID |
Phase Not Applicable |
Not yet recruiting |
4 |
27 Months |
230 |
António Sarmento, Cristina Granja, Prof., Irene Aragão, Isabel J Pereira, Lurdes Santos, Luís Filipe Azevedo, Prof., Mariana MS Santos, MSc. |
2020-06-18 |
| COVID&PREG: COVID-19 and Pregnancy Outcomes |
Coronavirus disease 19 infection |
RT PCR alone |
|
Female, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Universidade Nova De Lisboa |
|
Portugal |
2020-03-22 |
2023-12-31 |
COVID&PREG, COVID&PREG, NCT04416373 |
Phase Not Applicable |
Recruiting |
1 |
45 Months |
300 |
Alexandra Queirós, MD, Alexandra S Queiros, MD, Ana M Campos, PhD,MD, Maria J Alves, MD, Nadia Charepe, MD,MSc, Nadia Charepe, MSc, MD, Teresa Ventura, PhD,MD |
2020-06-08 |
| Use of Herbal Medicine like Tulasi, Amruth(Giloy), Turmeric, Ashwagandha as add on treatment in COVID-19 Patients |
Coronavirus disease 19 infection |
Variable regimens including Amruth , Shakti drops , Tulsi Arka , Turmeric plus |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Sriveda Sattva PvtLtd |
|
India |
2020-06-13 |
|
CTRI/2020/06/025592 |
Phase 4 Clinical |
Not yet recruiting |
1 |
|
50 |
Dr C R Jayanthi, Dr M Ravi Kumar Reddy |
2020-06-09 |
| Clinical Characteristics of Critically Ill Patients With COVID-19 |
Coronavirus disease 19 infection |
File Scanning alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Nevsehir Public Hospital |
|
Turkey |
2020-06-30 |
2020-07-25 |
2020-05-13T12_44_51, 2020-245, NCT04413435 |
Phase Not Applicable |
Recruiting |
1 |
|
105 |
Betül Kozanhan, Dr, Mehmet Akif Yaza, Yasin Tire, Dr |
2020-06-18 |
| STOIC: Steroids in COVID-19 Study |
Coronavirus disease 19 infection, Respiratory disease |
budesonide alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Oxford |
|
|
2020-06-11 |
2020-12-30 |
NCT04416399, STOIC, STOIC STUDY |
Phase 2 Clinical |
Not yet recruiting |
0 |
6 Months |
478 |
Magda Laskawiec, Mona Bafadhel, MBBS, PhD |
2020-06-10 |
| A phase II proof of concept trial to assess efficacy of LY-CoV555 in COVID-19 vulnerable populations |
Coronavirus disease 19 infection |
LY-CoV555 alone |
COVID19 Spike glycoprotein modulator |
|
Eli Lilly & Co |
|
|
|
|
|
Phase 2 Clinical |
Planned |
0 |
|
|
|
2020-06-05 |
| Ruxolitinib in the Treatment of Covid-19 |
Coronavirus disease 19 infection |
ruxolitinib alone |
Jak1 tyrosine kinase inhibitor, Jak2 tyrosine kinase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Clinica Zabala |
Novartis AG |
Argentina |
2020-06-01 |
2020-09-15 |
CZABALA, NCT04414098 |
Phase 2 Clinical |
Not yet recruiting |
1 |
3 Months |
100 |
Joaquin Castro, MD, Marcelo Iastrebner, MD |
2020-06-08 |
| COVIDOCRECHE: COVID-19 Infection and Transmission in Exposed, Confined and Community-based Infants |
Coronavirus disease 19 infection |
Nasopharyngeal swab test alone, Rapid detection test alone, Stool collection alone |
|
Healthy volunteers accepted, Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assistance Publique Hopitaux de Paris |
|
France |
2020-06-02 |
2021-06-02 |
2020-A01540-39, APHP200587, COVIDOCRECHE, NCT04413968 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
600 |
Eric LACHASSINNE, MD, Mohammed RAHAOUI, PM |
2020-06-08 |
| COVELEC: Protein Electrophoresis as a Tool for Complications Prediction in COVID-19 Hospitalized Patients |
Coronavirus disease 19 infection, Inflammatory disease |
serum protein electrophoresis alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Clinique de l'Estrée |
|
France |
2020-06-15 |
2021-06-30 |
2020-A01376-33, COVELEC, COVELEC, NCT04414059 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
155 |
Johanna MIMOUNI, Shahnaz KLOUCHE, Stephane DI MASCIO, MD, Stéphane DI MASCIO, MD |
2020-06-08 |
| Registry of Seraph-100 Microbind Affinity Blood Filter for COVID-19 Under EUA |
Acute lung injury, Coronavirus disease 19 infection, Dyspnea, Respiratory distress syndrome, Respiratory failure |
Seraph-100 Microbind Affinity Blood Filter alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cincinnati Children's Hospital Medical Center |
ExThera Medical LLC |
US |
2020-05-31 |
2021-12-31 |
001-SERAPH-100 FOR SARS-COV-2, NCT04413955 |
Phase Not Applicable |
Not yet recruiting |
1 |
19 Months |
100 |
Erdie De Peralta, Kelli Krallman, RN |
2020-06-09 |
| CovAged: Severe Acute Respiratory Syndrome-Coronavirus-2 and Loss of Autonomy in the Elderly |
Autonomic nervous system disease, Coronavirus disease 19 infection |
|
|
Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Center of Martinique |
|
France, Guadeloupe, Martinique |
2020-04-15 |
2023-04-15 |
20_RIPH3-02, CovAged, NCT04414319 |
Phase Not Applicable |
Recruiting |
5 |
36 Months |
350 |
Cecilia COFAIS, MD, Jérome TANGHE, MD, Laury ALLARD-SAINT-ALBIN, MD, Lidvine GODAERT, PHD, Maturin TABUE TEGUO, PHD, Moustapha DRAME, PHD, Seendy BARTHOLET, MD, Veronique ERDUAL, Véronique ERDUAL |
2020-06-09 |
| NIVISCO: Efficiency and Security of Nivolumab Therapy in Obese Individuals With COVID-19(COrona VIrus Disease) Infection |
Coronavirus disease 19 infection |
Routine standard of care alone, nivolumab alone |
Programmed cell death protein 1 inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Hospices Civils De Lyon |
|
France |
2020-06-15 |
2021-09-15 |
69HCL20_0478, NCT04413838, NIVISCO |
Phase 2 Clinical |
Not yet recruiting |
1 |
15 Months |
120 |
Dominique DELAUNAY, Emmanuel DISSE, Emmanuel DISSE, Pr, Pr |
2020-06-09 |
| COVAC1: Clinical trial to assess the safety of a coronavirus vaccine in healthy men and women |
Coronavirus disease 19 infection |
self-amplifying RNA vaccine (im, COVID-19), Imperial College London alone |
COVID19 Spike glycoprotein inhibitor |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Imperial College London |
Medical Research Council, United Kingdom Research & Innovation |
UK |
2020-04-01 |
2021-07-31 |
2020-001646-20, COVAC1, IRAS 279315, ISRCTN17072692 |
Phase 1 Clinical |
Recruiting |
5 |
16 Months |
320 |
Miss Ward, Prof Sheena McCormack |
2020-06-15 |
| ICOPE: Implementation of the Integrated Care of Older People App and ICOPE Monitor in Primary Care |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Liege |
Centre Hospitalier Universitaire de Toulouse |
Belgium |
2020-10-31 |
2021-11-30 |
GERULIEGE/SG/DSR/ICOPE, ICOPE, NCT04413877 |
Phase Not Applicable |
Not yet recruiting |
1 |
13 Months |
600 |
Dolores Sanchez-Rodriguez, MD PhD, Sophie Gillain, MD PhD |
2020-06-05 |
| A clinical trial to evaluate safety and efficacy of polyherbal capsule Astha-15 used as an add on therapy with standard care of therapy as an immunity booster in the suspected and COVID-19 diagnosed patients |
Coronavirus disease 19 infection |
Astha-15 alone, standard care of therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Dalmia Centre For Research & Development |
|
India |
2020-06-08 |
|
CTRI/2020/06/025590, DAL/CT/001/AST/2020 |
Phase 3 Clinical |
Not yet recruiting |
4 |
|
120 |
Dr A Gopal Rao, Dr Amulya Bhati, Dr Prastita P Kshirsagar, Dr Vinod Kumar, Mukesh Kumar |
2020-06-08 |
| Comparison of two different laryngoscopes using COVID barrier box |
Coronavirus disease 19 infection, General anesthesia |
Ambu King video laryngoscope alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
All India Institute of Medical Sciences Bhubaneswar |
|
India |
2020-06-15 |
|
CTRI/2020/06/025589 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
60 |
Sangeeta Sahoo |
2020-06-05 |
| Data of patients with Corona virus disease admitted to the ICU at P.D. Hinduja Hospital, Mumbai |
Coronavirus disease 19 infection |
|
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
P. D. Hinduja hospital and medical research centre |
|
India |
2020-06-08 |
|
CTRI/2020/06/025588 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
400 |
Dr Alex Fonseca, Dr Farhad N Kapadia |
2020-06-08 |
| SEV-Covid Trial: Safety and efficacy of antiviral combination therapy in symptomatic patients of Covid-19 infection - a randomized, control trial |
Coronavirus disease 19 infection |
Standard Treatment(STns) alone, Standard Treatment(STs) alone, oseltamivir alone |
Exo-alpha sialidase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
All India Institute of Medical Sciences |
|
India |
2020-06-15 |
|
CTRI/2020/06/025575, SEV-Covid Trial |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
175 |
Prasan Kumar Panda |
2020-06-08 |
| Effect of Ayurvedic medicine in the Prophylaxis for COVID-19 of AYUSH healthcare workers , Dept of AYUSH, TS and CCRAS- NIIMH, Hyderabad |
Coronavirus disease 19 infection |
Ayush 64 alone, Chavanprash alone, Samshamani vati alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Aayush Healthcare |
|
India |
2020-06-15 |
|
CTRI/2020/06/025561 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
500 |
Dr Srikanth Babu Perugu |
2020-06-08 |
| ATENEA-Co-300: ATENEA-Co-300 study |
Coronavirus disease 19 infection |
CIGB-300 alone, treatment established in the national action protocol alone |
Casein kinase II inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Center for Genetic Engineering and Biotechnology |
Ministerio de Salud Publica |
Cuba |
2020-06-01 |
|
ATENEA-Co-300, IG/CIGB300I/CV/2001, RPCEC00000317 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
|
20 |
Idania Baladron Castrillo, Leticia del Rosario Cruz, Silvio Perea Rodriguez |
2020-06-08 |
| A clinical trial of InspectIR portable breathalyzer for the detection of COVID-19 infection |
Coronavirus disease 19 infection |
InspectIR portable breathalyzer alone |
|
|
Inspectir Systems LLC |
|
US |
2020-05-27 |
|
|
Phase Not Applicable |
Recruiting |
1 |
|
|
Dr. Gustavo Day |
2020-06-05 |
| TRAiN: Rapid-Cycle Re-Implementation of Training Facilities in Norway |
Coronavirus disease 19 infection |
access to training facility alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
The Norwegian Directorate for Health and Social Affairs |
University of Oslo |
Norway |
2020-05-22 |
2022-05-19 |
NCT04406909, REK 143984, TRAiN |
Phase Not Applicable |
No longer recruiting |
2 |
23 Months |
4000 |
Magnus Løberg, MD PhD, Mette Kalager, MD PhD |
2020-06-12 |
| A clinical study of Ayurvedic formulations in the treatment of Mild to Moderate COVID-19 patients |
Coronavirus disease 19 infection |
Variable regimens including AYUSH-64 , Sanshamani Vati Plus , Yashtimadhu |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Council of Scientific and Industrial Research (India), Ministry of Ayush |
|
India |
|
|
AYUSH-CSIR-TRT-01, CTRI/2020/06/025557 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
420 |
DR ARVIND CHOPRA, Vaidya Manohar Gundeti |
2020-06-08 |
| Acute and chronic cardiovascular and respiratory changes in COVID-19 hospitalized patients and the effect of physical rehabilitation supervised by telecommunication |
Coronavirus disease 19 infection |
physical rehabilitation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fundação Universidade Federal De São Carlos, Universidade Estadual Paulista (UNESP) |
|
Brazil |
2020-07-01 |
|
32134720.4.1001.5398, 4.039.688, RBR-9y32yy, U1111-1252-5187 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Alessandro Domingues Heubel, Ariane Aparecida Viana, Emmanuel Gomes Ciolac, Renata Gonçalves Mendes |
2020-06-08 |
| A open-labelled study to assess the safety and efficacy of a clinical course of oral apabetalone in hospitalized subjects with 2019-nCoV infection |
Coronavirus disease 19 infection |
apabetalone alone |
APOA1 gene stimulator, Angiotensin converting enzyme 2 inhibitor, Bromodomain containing protein 2 inhibitor, Bromodomain containing protein 4 inhibitor |
|
Resverlogix Corp |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-06-04 |
| A phase Ib, proof-of-concept, randomized, double-blind, placebo-controlled clinical study to evaluate the potential of TRV-027 to treat acute lung injury contributing to acute respiratory distress syndrome (ARDS) in COVID-19 patients |
Acute lung injury, Adult respiratory distress syndrome, Coronavirus disease 19 infection |
TRV-027 alone |
Angiotensin II AT-1 receptor antagonist, Beta-arrestin stimulator |
Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
British Heart Foundation, Imperial College London |
Trevena Inc |
UK |
|
|
|
Phase 1b Clinical |
Planned |
1 |
|
60 |
|
2020-06-18 |
| Using Homeopathic Combinations for Prevention and Treatment of Viral Fevers including COVID 19 |
Coronavirus disease 19 infection, Fever, Viral infection |
Variable regimens including Aconite 30 , Allium Cepa 30 , Arsenic Album 30 , Echinacia 0 , Eupatorium 30 , Gelsmium 30 , Influenzum 30 , Thuja 0 |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sanjay Gandhi Postgraduate Institute of Medical Sciences |
|
|
2020-06-18 |
|
CTRI/2020/06/025530 |
Phase Not Applicable |
Not yet recruiting |
0 |
|
10000 |
Dr AK Gupta, Dr Anil Agarwal, Dr Piyush Gupta |
2020-06-05 |
| SCENARIO: Prevalence of SARS-CoV-2 (COVID-19) in pregnancy and at delivery in Franconia, Germany |
Coronavirus disease 19 infection, Pregnancy disorder |
|
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universitatsklinikum Erlangen |
|
Germany |
2020-06-02 |
|
185_20B, DRKS00022088, SCENARIO |
Phase Not Applicable |
Recruiting |
1 |
|
2550 |
Alexander Hein |
2020-06-16 |
| Clinical trial on Immunity and antiviral for quarantine patients of COVID-19 |
Coronavirus disease 19 infection |
Amrta Karuna Syrup alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Vopec Pharmaceuticals Pvt Ltd |
|
India |
2020-06-01 |
|
CT/Vopec/Amrta Karuna /2020 version 1.0, CTRI/2020/06/025527 |
Phase 4 Clinical |
Not yet recruiting |
1 |
|
30 |
Dr Dinesh |
2020-06-05 |
| Guduchi Ghanavati as a prophylactic measure among population at high risk to SARS-CoV-2 exposure |
Coronavirus disease 19 infection |
Guduchi Ghanavati alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
GUJARAT AYURVED UNIVERSITY |
|
India |
2020-06-09 |
|
CTRI/2020/06/025525 |
Phase Not Applicable |
Not yet recruiting |
3 |
|
20000 |
Anup Thakar, Bharat Kalsariya, Harshit Shah, Kalpesh Panara, Naresh Jain, Sweety Ruparel |
2020-06-05 |
| Can the Prediction Market Improve Predictions of COVID-19 |
Coronavirus disease 19 infection |
Prediction Market alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National University of Singapore |
|
Singapore |
2020-05-15 |
2020-05-17 |
NCT04410692, SG-COVID |
Phase Not Applicable |
Completed |
1 |
|
560 |
Teck Ho, PhD |
2020-06-08 |
| To observe the impact of Ayurveda Kwath in Healthy and Suspected persons for COVID-19 |
Coronavirus disease 19 infection |
Ayurveda Kwath alone |
|
Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Dr.S R.Rajasthan Ayurved University Jodhpur |
|
India |
2020-06-10 |
|
CTRI/2020/06/025526 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
500 |
Prof Govind Sahay Shukla |
2020-06-05 |
| ACCESS: A clinical study of real-world monitoring of COVID-19 Vaccines |
Coronavirus disease 19 infection |
|
|
|
European Medicines Agency, Universiteit Utrecht |
|
Europe |
|
|
ACCESS |
Phase Not Applicable |
Status not specified |
0 |
|
|
|
2020-06-04 |
| A phase II, open-label, non-randomized, clinical trial of the safety and efficacy of the CovidCare app to support self-monitoring for COVID-19 symptoms in self-isolation and to determine the impacts on mental health |
Anxiety disorder, Coronavirus disease 19 infection, Depression |
CovidCare app alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Melbourne |
|
Australia |
2020-06-08 |
|
ACTRN12620000640909, U1111-1251-7257 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
200 |
A/Prof Victoria Palmer, Ms Maria Potiriadis |
2020-06-09 |
| TTCOV19: Timing of Tracheotomy in Covid-19 Patients |
Coronavirus disease 19 infection |
Early tracheotomy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sahlgrenska University Hospital |
|
Sweden |
2020-06-04 |
2021-02-01 |
HBERGQUIST, NCT04412356, TTCOV19 |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
180 |
Henrik Bergquist, Assoc Prof, Måns Eeg-Olofsson, Assoc Prof |
2020-06-11 |
| A phase III trial of bemcentinib for COVID-19 |
Coronavirus disease 19 infection |
bemcentinib alone |
Axl tyrosine kinase receptor inhibitor |
|
BerGenBio AS |
|
UK |
|
|
|
Phase 3 Clinical |
Planned |
1 |
|
|
|
2020-06-04 |
| XoGloCoV2: To study the treatment of COVID-19 with severe viral pneumonia by using purified stem cell exosomes |
Coronavirus disease 19 infection, Lymphocytopenia, Pulmonary fibrosis, Respiratory failure, Viral pneumonia |
XoGlo alone |
|
|
Kimera Labs |
University Hospital Ulm |
Germany |
2020-04-26 |
2020-12-31 |
2020-002326-90, 89081, ISRCTN33578935, XoGloCoV2 |
Phase 2 Clinical |
Recruiting |
1 |
8 Months |
64 |
Prof Marion Schneider |
2020-06-05 |
| A compassionate use program of Organicell Flow for the treatment of COVID-19 infection |
Coronavirus disease 19 infection |
Organicell Flow alone |
|
|
Organicell Regenerative Medicine |
|
US |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
|
|
2020-06-04 |
| Efficacy and Safety of Hydroxychloroquine and Favipiravir in the Treatment of Mild to Moderate COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
favipiravir alone, Variable regimens including azithromycin , favipiravir , hydroxychloroquine |
RNA polymerase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Ministry of Health of Turkey |
Ankara City Hospital Bilkent, Ankara Training and Research Hospital, Ankara University, Ege University Hospital (Application and Research Center), Hacettepe University, Istanbul University Faculty of Medicine, Istanbul University-Cerrahpasa, Kayseri City Hospital, Kocaeli Derince Education and Research hospital, SB Istanbul Education and Research Hospital, Sultan Abdulhamid Han Training and Research Hospital, Tepecik Training and Research Hospital, Umraniye education and research hospital |
Turkey |
2020-05-08 |
2020-07-30 |
COVID-19-FAV, NCT04411433 |
Phase 3 Clinical |
Recruiting |
1 |
2 Months |
1000 |
Prof. Ates KARA, MD, Prof. Ateş KARA, MD, Prof. Ateş Kara, MD |
2020-06-05 |
| Novel COVID-19: A National Analysis |
Coronavirus disease 19 infection, Respiratory tract infection, Viral pneumonia |
|
|
|
Assiut University |
|
Egypt |
2020-05-20 |
2020-06-30 |
NCT04413045, NOVEL COVID-19 PREVALENCE |
Phase Not Applicable |
Recruiting |
1 |
1 Month |
50 |
Mohamed F. Mostafa, MD |
2020-06-05 |
| COVID-19_LF: Clinical Assessment of Oral Lactoferrin as a Safe Antiviral and Immunoregulatory in Treating COVID-19 Disease |
Coronavirus disease 19 infection |
bovine apolactoferrin alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Research Center Patent Office |
Egyptian Military Medical Services |
Egypt |
2020-06-01 |
2020-09-30 |
COVID-19_LF, COVID-19_LF, NCT04412395 |
Phase 2 Clinical |
Not yet recruiting |
4 |
4 Months |
516 |
Bassim Mohamed, PhD, Christine Gindy, B Pharm, Khaled Prince, B Pharm, Marawan Abdelbaset, PhD, Osama Azmy, MD, Rehab Hegazy, PhD, Rehab Ragab Hegazy, Wafaa Abdel Aal, MD |
2020-06-05 |
| A Study of LY-3819253 (LY-CoV555) in Participants Hospitalized for COVID-19 |
Coronavirus disease 19 infection |
LY-CoV555 alone |
COVID19 Spike glycoprotein modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Eli Lilly & Co |
AbCellera Biologics Inc |
US |
2020-05-28 |
2020-08-23 |
17823, J2W-MC-PYAA, NCT04411628 |
Phase 1 Clinical |
Recruiting |
10 |
2 Months |
40 |
GERARD J CRINER, Mark J Mulligan, Mary K Lewinski, Michael L Dougan, Nadine G Rouphael, Pauline K Park, Peter Chen, Rudolph J Kotula, William A Fischer |
2020-06-18 |
| COVID-19 HUSO: Clinical trial, randomized, open-label, to evaluate the efficacy of high-dose vitamin D in patients with COVID-19 pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
vitamin D (Thorens) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Universitario Severo Ochoa |
|
Spain |
2020-05-28 |
|
01052020, 2020-002312-43, COVID-19 HUSO |
Phase 3 Clinical |
Recruiting |
1 |
|
82 |
Miguel Cervero |
2020-06-04 |
| CovidCare - 1: Surveillance and care for confirmed and suspected patients with COVID-19 in general practice: an observational study |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Heidelberg |
AOK Baden-Württemberg |
Germany |
2020-05-05 |
|
CovidCare - 1, DRKS00022054, S-266/2020 |
Phase Not Applicable |
Recruiting |
1 |
|
400 |
Frank Peters-Klimm, Markus Qreini |
2020-06-05 |
| A clinical trial to investigate the efficacy and safety of a new compound for the treatment of COVID-19, called BDB-001. Patients in the trial will be randomly allocated to either the new treatment or the conventional treatment and will be aware of which treatment they are receiving |
Coronavirus disease 19 infection, Respiratory distress syndrome |
BDB-1 alone |
Complement C5a factor inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Beijing Defengrei Biotechnology Co Ltd, Staidson (Beijing) Biopharmaceutical Co Ltd |
|
Spain, Europe |
2020-05-08 |
|
2020-001671-32, Name: NMPA Number: 020L00003, STS-BDB001-04 |
Phase 2 Clinical |
No longer recruiting |
1 |
|
60 |
Lixin Jiang |
2020-06-12 |
| BATS: Best available treatment study for inflammatory conditions associated with COVID-19 |
Coronavirus disease 19 infection, Inflammatory disease |
|
|
|
Imperial College London |
|
UK |
2020-05-08 |
2022-05-31 |
BATS, IRAS 284825, ISRCTN69546370 |
Phase Not Applicable |
Recruiting |
2 |
24 Months |
1800 |
Prof Levin |
2020-06-17 |
| ImmunoCorona: Evaluation of the synergistic effect of sequential administration of two immunostimulant products: Immuno-1 and Immuno-2 for the stimulation of the immune response in older adults. Exploratory study |
Coronavirus disease 19 infection |
Immuno-1 plus Immuno-2 |
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Finlay Institute |
National Center for Biopreparations (BIOCEN) |
Cuba |
2020-05-19 |
|
ImmunoCorona, RPCEC00000315 |
Phase 2 Clinical |
Recruiting |
1 |
|
60 |
Dagmar Garcia Rivera, Rinaldo Puga Gomez |
2020-06-04 |
| COVIDIAB-13: Covid-19 and Diabetes in West of Algeria |
Coronavirus disease 19 infection, Diabetes mellitus, Lung embolism |
glucocorticoid therapy alone, oxygen therapy alone, Variable regimens including azithromycin , hydroxychloroquine , insulin , lopinavir + ritonavir , low molecular weight heparin , zinc sulfate |
HIV protease inhibitor |
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Université de Tlemcen, Algeria |
|
Algeria |
2020-04-01 |
2020-06-30 |
COVIDIAB-13, COVIDIAB-13, NCT04412746 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
100 |
ALI LOUNICI, ALI LOUNICI, Professor, Benattou ZIANE, Professor, Samia BENCHOUK, Professor |
2020-06-08 |
| VME-CORONA: VA-MENGOC-BC / COVID 19 |
Coronavirus disease 19 infection |
meningitis B (Cuba vaccine), GlaxoSmithKline/Finlay Institute alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Finlay Institute |
BioCubaFarma |
Cuba |
2020-04-24 |
2020-06-30 |
RPCEC00000314, VME-CORONA, VME-CORONA |
Phase 2 Clinical |
Recruiting |
1 |
2 Months |
17000 |
Dagmar Garcia Rivera, Maria Toledo Romani |
2020-06-09 |
| ISACS-STEMI COVID-19: Primary Angioplasty for STEMI During COVID-19 Pandemic |
Acute coronary syndrome, Coronavirus disease 19 infection, Myocardial infarction |
Percutaneous coronary revascularization alone |
|
|
Universita' Degli Studi Del Piemonte Orientale "Amedeo Avogadro" |
|
Italy |
2020-05-05 |
2020-06-02 |
115/20, ISACS-STEMI COVID-19, NCT04412655 |
Phase Not Applicable |
No longer recruiting |
1 |
|
6609 |
|
2020-06-12 |
| A clinical trial of nafamostat for the treatment of patients with COVID-19 infection |
Coronavirus disease 19 infection |
nafamostat (inhaled, COVID-19), University of Tokyo/ Daiichi Sankyo/ RIKEN alone |
Serine protease inhibitor |
|
Sun Pharmaceutical Industries Ltd |
|
India |
|
|
|
Phase Not Applicable |
Not yet recruiting |
1 |
|
|
|
2020-06-03 |
| A Longitudinal Study of COVID-19 Sequelae and Immunity |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Institute of Allergy and Infectious Diseases |
National Institutes of Health Clinical Center |
US |
2020-06-22 |
2027-12-31 |
20-I-0123, 200123, NCT04411147 |
Phase Not Applicable |
Recruiting |
1 |
90 Months |
900 |
Bryan P Higgins, R.N., Michael C Sneller, M.D. |
2020-06-18 |
| Epigenetic Tools as Prognostic Predictors in Covid19 |
Confusion, Coronavirus disease 19 infection, Hypotension, Respiratory distress syndrome, Tachycardia, Tachypnea, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Bakirkoy Dr. Sadi Konuk Research and Training Hospital |
Istanbul University |
Turkey |
2020-05-21 |
2020-12-31 |
2020/143, NCT04411563 |
Phase Not Applicable |
Recruiting |
2 |
7 Months |
105 |
Asuman Gedikbasi, Assoc.Prof., Gokhan T Adas, Prof., Gokhan T. Adas, Prof, Gokhan T. Adas, Prof., Kadriye Yaşar, Prof., Nilgün Isiksacan, Assoc.Prof., Oya G. Hergünsel, MD, Intensivist, Sacide Pehlivan, Prof., Zafer Çukurova, Assoc.Prof. |
2020-06-15 |
| Menstrual Cycle Characteristics of Healthcare Professionals |
Coronavirus disease 19 infection, Dysmenorrhea, Menstruation disorder |
|
|
Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Haydarpasa Numune State Hospital |
Saglik bilimleri universtesi |
Turkey |
2020-04-10 |
2020-11-10 |
HNEAH KAEK 2020/KK/, MINISTRY OF HEALTH, NCT04413058 |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
200 |
Sevcan Arzu Arinkan, Sevcan Arzu Arinkan, M.D. |
2020-06-04 |
| OPTIMAL: Optimizing Outcomes With Physical Therapy Treatment for IndividuALs Surviving an ICU Admission for Covid-19 |
Anxiety disorder, Cognitive disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder |
ICU Recovery + Physical Therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Kentucky |
|
US |
2020-05-01 |
2021-05-01 |
59097, NCT04412330, OPTIMAL |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
40 |
Evan Cassity, MS, Kirby Mayer, DPT, PhD(c), Kirby P Mayer, PhD |
2020-06-05 |
| COVID-19 Convalescent Plasma (CCP) Transfusion |
Coronavirus disease 19 infection, Hypoxia, Multiple organ failure, Respiratory failure, Sepsis |
COVID convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Mississippi |
|
US |
2020-06-01 |
2022-05-31 |
2020-0137, NCT04412486 |
Phase 0 Clinical |
Recruiting |
1 |
24 Months |
100 |
Gailen D Marshall, Jr., MD, PhD, Lucar Lloveras, MD, Utsav Nandi, MD, Vishnu Garla, MD |
2020-06-04 |
| COLC: COVID-19, Obesity and Lifestyle in Children |
Coronavirus disease 19 infection, Obesity |
|
|
Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Maastricht University Medical Center |
|
Netherlands |
2020-05-06 |
2021-05-06 |
2020-1330, COLC, NCT04411511 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
4000 |
Anita CE Vreugdenhil, Anita CE Vreugdenhil, Dr., Anita CE Vreugdenhil, dr., Gabrielle L ten Velde, Drs., Judith W Lubrecht, Drs., Lisanne Arayess, Drs., Lisanne Arayess, drs. |
2020-06-04 |