Last updated: Jul 12, 2020 - 02:00 BST

Title Indication Intervention Actions PatientSelection Sponsor Collaborator Country StartDate EndDate Identifiers Phase Recruitment Status Sites Trial Duration Enrollment Count Contacts LastChanged
Evaluating Adaptive Dispenser Initiation Protocols for MySafeRx During Post-detox Buprenorphine Treatment- a Pilot Study Coronavirus disease 19 infection, Opiate dependence MySafeRx Inspire Plus alone, buprenorphine + naloxone alone, coaching alone, manual lockbox alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of South Florida Cambridge Health Alliance US 2020-06-24 2021-02-01 NCT04449744, PRO00038163 - PILOT, R01CE003039 Phase 2 Clinical Not yet recruiting 0 7 Months 30 Cassandra Harding, MPH, Kathleen Moore, PhD, Melissa Carlson, BS, Zev Schuman-Olivier, MD 2020-07-11
MONITOR: 'NORPLASMA' COVID-19 Convalescent Plasma Treatment Monitoring Study Coronavirus disease 19 infection COVID-19 convalescent plasma alone, NORPLASMA MONITOR alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Oslo University Hospital Norway 2020-07-06 2025-05-31 148622, MONITOR, NCT04463823 Phase Not Applicable Not yet recruiting 1 58 Months 500 Lise Sofie Haug Nissen-Meyer, Ph.D, Lise Sofie Haug Nissen-Meyer, Ph.D., Tor Audun Hervig, Ph.D 2020-07-11
COBETOX: Effects of COVID-19 Infection on Beta-cell Function in Euglycemic Patients Coronavirus disease 19 infection arginine hydrochloride alone, stimulation test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universita degli Studi di Milano Ospedale Luigi Sacco Azienda Ospedaliera Polo Universitario Italy 2020-06-30 2021-06-30 6/2020, COBETOX, NCT04463849 Phase 2 Clinical Recruiting 1 12 Months 24 Paolo Fiorina, MD, Paolo Fiorina, MD, PhD, Teresa Letizia, Dr. 2020-07-11
Efficacy and Safety Study of Nitazoxanide (NTX) in the Treatment of Patients With SARS-CoV-2 Virus Infection (COVID-19) Coronavirus disease 19 infection nitazoxanide alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Laboratorios Roemmers S.A.I.C.F. Argentina 2020-06-26 2020-10-26 NCT04463264, NTZ-COVID ARG1 Phase 2/Phase 3 Clinical Recruiting 1 4 Months 135 Diego Enriquez, MD, Marcelo Silva, MD 2020-07-10
Characteristics of Critically Ill COVID 19 Patients Coronavirus disease 19 infection Assiut University Egypt 2020-07-08 2020-08-10 NCT04465058, YTE Phase Not Applicable Recruiting 1 1 Month 50 Rasha Hamed, lecturer of anaesthesia, rasha hamed, MD 2020-07-10
A phase IIb, proof-of-efficacy study of OVX-836 for the potential prevention of COVID-19 infection Coronavirus disease 19 infection OVX-836 alone Nucleoprotein modulator Osivax Phase 2b Clinical Planned 0 3500 2020-07-10
A Study to Evaluate the Safety, Pharmacokinetics (PK) and Efficacy of TAK-671 for the Treatment of Coronavirus Disease (COVID) 2019 in Adults Coronavirus disease 19 infection, Respiratory disease TAK-671 alone, standard of care alone Trypsin inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Takeda Pharmaceutical Co Ltd US 2020-07-08 2020-08-28 NCT04464460, TAK-671-1501, U1111-1252-9426 Phase 1b Clinical Not yet recruiting 1 1 Month 40 Medical Director, Takeda Study Registration Call Center 2020-07-10
ImmuneSense Lyme Study Anaplasma infection, Babesia infection, Chronic fatigue syndrome, Coronavirus disease 19 infection, Cytomegalovirus infection, Ehrlichia infection, Epstein Barr virus infection, Influenza virus infection, Lyme disease, Multiple sclerosis, Rheumatoid arthritis, Rocky mountain spotted fever, Systemic lupus erythematosus, Treponema pallidum infection immunoSEQ Dx test alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Adaptive Biotechnologies Corp IQVIA RDS Pty Ltd 2020-06-25 2021-12-30 NCT04422314, PRO-00717 Phase Not Applicable Not yet recruiting 0 18 Months 990 Emily Svejnoha, Ms., Jennifer Dines, MD, Thomas Manley, MD 2020-07-10
COVID19 Severity Prediction and Health Services Research Evaluation Coronavirus disease 19 infection, Dyspnea, Respiratory distress syndrome, Sepsis, Septic shock Hospital Galdakao-Usansolo Biocruces Bizkaia Health Reseach Institute, Hospital Costa del Sol, Hospital Universitario Araba(Spain), Hospital Universitario Donostia, Hospital de Basurto, Hospital del Mar, Instituto de Salud Carlos III, University Hospital of the Nuestra Señora de Candelaria Spain 2020-06-01 2021-12-31 COVID19_0459, NCT04463706 Phase Not Applicable Recruiting 1 19 Months 20000 Susana Garcia-Gutierrez, PhD, Susana García-Gutierrez, PhD 2020-07-10
Air Pollution and COVID-19 Mortality in Geriatric Patients: a Multicenter Study Coronavirus disease 19 infection Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopitaux Universitaires de Strasbourg Belgium, France 2020-06-04 2020-09-04 7922, NCT04463862 Phase Not Applicable Recruiting 11 3 Months 250 Bertrand FOUGERE, MD, Claire ROUBAUD BAUDRON, MD, Cédric ANNWEILER, MD, Delphine BETRO, MD, Frédéric BLANC, MD, Georges KALTENBACH, MD, Jean-Baptiste BEUSCART, MD, Laure DE DECKER, MD, Matthieu LILAMAND, MD, Natahlie COMPTE, MD, Nathalie COMPTE, MD, Rachid MAHMOUDI, MD, Rachide MAHMOUDI, MD, Romain DECOURS, MD, Thomas BOURDREL, MD, Thomas VOGEL, MD 2020-07-10
Coropreg: Covid-19 in Pregnancy: a French Population-based Cohort of Women and Newborns Coronavirus disease 19 infection Female Assistance Publique Hopitaux de Paris INSERM, Epopé team France 2020-05-11 2022-10-31 APHP200513, Coropreg, NCT04463758 Phase Not Applicable Recruiting 1 29 Months 3060 Catherine Deneux-Tharaux, MD, PhD, Jean-Marc Treluyer, M.D., PhD, Laurence Lecomte, PhD, Pierre Yv Ancel, MD, PhD 2020-07-10
Mavrilimumab to Reduce Progression of Acute Respiratory Failure in COVID-19 Pneumonia and Systemic Hyper-inflammation Coronavirus disease 19 infection, Hypoxia, Inflammatory disease, Respiratory failure, Viral pneumonia mavrilimumab alone C-reactive protein inhibitor, Chemokine CC22 ligand inhibitor, GM-CSF receptor antagonist, Hemoglobin scavenger receptor antagonist, Metalloprotease-1 inhibitor, Metalloprotease-3 inhibitor, Small inducible cytokine A17 ligand inhibitor, VEGF gene inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Virginia Commonwealth University Kiniksa Pharmaceuticals Ltd US 2020-08-31 2021-08-31 HM20019145, NCT04337216, NCT04463004 Phase 2 Clinical Recruiting 1 12 Months 60 Antonio Abbate, MD, PhD 2020-07-11
A trial to evaluate COVID-HIG in a post-exposure prophylaxis study in individuals at high risk of exposure to COVID-19, such as front-line health care workers and military personnel and other high-risk populations Coronavirus disease 19 infection COVID-HIG alone Emergent BioSolutions Inc, Mount Sinai Health System, National Institute of Allergy and Infectious Diseases US Phase Not Applicable Planned 1 2020-07-10
A phase II/III clinical trial of NVX‑CoV2373 for the potential prevention of COVID-19 infection Coronavirus disease 19 infection NVX‑CoV2373 alone Novavax Inc Phase 2/Phase 3 Clinical Planned 0 2020-07-10
A phase II clinical trial of TXA-127 in hospitalized COVID-19 patients who are not in the Intensive Care Unit (ICU) Coronavirus disease 19 infection TXA-127 alone Angiotensin II receptor modulator Constant Therapeutics LLC Israel, Italy, US Phase 2 Clinical Planned 3 2020-07-10
Safety and Efficacy of PHR160 Spray on the Outcomes of Patients With COVID-19 Coronavirus disease 19 infection, Dyspnea Variable regimens including PHR160 spray , azithromycin , hydroxychloroquine , naproxen Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Baqiyatallah University of Medical Sciences Iran 2020-07-15 2020-12-15 IR.BMSU.REC.1399.176, NCT04463420 Phase 2 Clinical Recruiting 1 5 Months 224 Mohammad Sadegh Bagheri Baghdasht 2020-07-10
Emergency Department (ED) Self-Monitoring Pilot COVID-19 Anxiety disorder, Coronavirus disease 19 infection CovidX application alone, pulse oximeter alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Michigan Vironix LLC US 2020-07-31 2021-04-30 HUM00181946, NCT04462783 Phase Not Applicable Not yet recruiting 1 9 Months 200 Kathleen Li, MD 2020-07-10
Remote COVID-19 Symptom Tracking for Cancer Patients at Home During the Pandemic Cancer, Coronavirus disease 19 infection SCH Intervention alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Utah US 2020-04-21 2021-05-31 IRB_00131892, NCT04464486 Phase Not Applicable Recruiting 1 13 Months 300 Kathleen Mooney, PhD 2020-07-10
Characteristics and Outcomes of Patients Admitted to Swedish Intensive Care Units for COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Linkoeping Region Ostergotland Sweden 2020-03-06 2020-05-06 NCT04462393, SWECOVID Phase Not Applicable Completed 1 2 Months 1563 Michelle Chew 2020-07-10
A Validation Study of COVID-19 At-Home Saliva Test by Phosphorus Coronavirus disease 19 infection saliva-based COVID-19 at-home viral test, Phosphorus Inc alone Care Access Research Phosphorus Inc US Phase Not Applicable Not yet recruiting 1 2020-07-10
Novel Corona Virus-2019-nCov vaccine by intradermal route in healthy subjects Coronavirus disease 19 infection nCov vaccine(Cadila Healthcare Limited) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Zydus Cadila Healthcare Ltd India 2020-07-13 CTRI/2020/07/026352, NCOV 1002 Phase 1/Phase 2 Clinical Not yet recruiting 1 1048 Dr Kevinkumar Kansagra, Dr Ravindra Mittal, Dr Taufik Momin 2020-07-10
Efficacy and Safety of Sirolimus in COVID-19 Infection Coronavirus disease 19 infection, Leukopenia, Lymphocytopenia, Viral pneumonia sirolimus alone, standard of care alone mTOR inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Alexandria Egypt 2020-07-25 2020-10-30 NCT04461340, SIROLIMUS IN COVID 19 Phase 2 Clinical Not yet recruiting 2 3 Months 40 Ayman I Baess, MD, Heba M El weshahi, MD, Mohamed Mamdouh Elsayed, MD, Nermine H Zakaria, MD 2020-07-11
COVID-19 Convalescent Plasma as Prevention and Treatment for Children With Underlying Medical Conditions Congenital heart defect, Coronavirus disease 19 infection, Lung disease, Respiratory failure anti-SARS-CoV-2 human convalescent plasma alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) University of California Los Angeles US 2020-08-31 2024-12-31 IRB#20-001263, NCT04462848 Phase 1 Clinical Not yet recruiting 1 52 Months 30 Jaime G Deville, M.D., Michele F Carter, R.N. 2020-07-10
A phase II clinical trial of GP-1681 for the potential treatment of COVID-19 and the resulting cytokine storm Coronavirus disease 19 infection esuberaprost sodium (COVID-19-related hypercytokinemia), CytoAgents alone Cytokine receptor antagonist, Unspecified GPCR agonist CytoAgents Inc Phase 2 Clinical Planned 0 2020-07-10
A phase I clinical trial of GP-1681 for the potential treatment of COVID-19 and the resulting cytokine storm Coronavirus disease 19 infection esuberaprost sodium (COVID-19-related hypercytokinemia), CytoAgents alone Cytokine receptor antagonist, Unspecified GPCR agonist CytoAgents Inc Phase 1 Clinical Planned 0 2020-07-10
NCOVIP: Northeast COVID-19 and Pregnancy Study Group Birth complication, Coronavirus disease 19 infection, Pregnancy disorder RT-PCR alone, rapid test alone Female Instituto Materno Infantil Prof. Fernando Figueira Brazil 2020-07-01 2022-12-20 NCOVIP, NCOVIP, NCT04462367 Phase Not Applicable Not yet recruiting 1 29 Months 180 LEILA KATZ, MD, PhD, MELANIA M AMORIM, MD, PhD 2020-07-10
NAT-COV-SURV: National Covid-19 Surveillance Physicians Coronavirus disease 19 infection SARS-CoV2 antibody test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Heinrich Heine Universitat Dusseldorf Arbeitsgemeinschaft Intensivmedizin e.V Germany 2020-06-01 2020-09-30 2020_2, NAT-COV-SURV, NCT04459312 Phase Not Applicable Recruiting 1 4 Months 600 Detlef Kindgen-Milles, Prof. 2020-07-09
TOF-COVID: Sparing in Neuromuscular Blockade in COVID 19 ICU Coronavirus disease 19 infection Mechanical ventilation alone, Neuromuscular blockade agents infusion alone, Neuromuscular blockade monitor alone, TOF protocol alone, atracurium plus cisatracurium besilate Nicotinic acetylcholine receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospices Civils De Lyon France 2020-06-01 2020-06-01 2020_TOF-COVID, NCT04459533, TOF-COVID Phase Not Applicable Completed 1 250 2020-07-10
A pivotal, phase III clinical trial to evaluate the safety and efficacy of NVX-CoV2373 in healthy subjects Coronavirus disease 19 infection NVX-CoV2373 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted Novavax Inc Phase 3 Clinical Planned 0 30000 2020-07-09
IL-12RB and TNF-alpha Gene Polymorphism and Susceptibility and Progress of Covid-19 SARS-CoV-2: A Case-Control Study Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assiut University Egypt 2020-06-16 2020-07-30 ASSIUTU15, NCT04462120 Phase Not Applicable No longer recruiting 2 1 Month 100 Aliae AR Mohamed Hussein 2020-07-10
A clinical trial of IRL-201104 for the potential treatment of COVID-19 related Acute Respiratory Distress Syndrome (ARDS) Coronavirus disease 19 infection, Respiratory distress syndrome IRL-201104 alone Chaperonin stimulator DynPort Vaccine Company LLC, Immune Regulation Ltd US Phase Not Applicable Planned 1 2020-07-09
Worldwide Trends on COVID-19 Research After the Declaration of COVID-19 Pandemic Coronavirus disease 19 infection Variable regimens including Convalescent plasma , DAS-181 , hydroxychloroquine , interferon beta-1a , ivermectin Chloride channel modulator, Exo-alpha sialidase modulator, Muscarinic receptor antagonist Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Qassim University Saudi Arabia 2020-07-25 2020-09-20 COAHS, NCT04460547 Phase Not Applicable Not yet recruiting 1 1 Month 200 Dr Shiva Shankar Bugude 2020-07-11
CoviDiagMS: SARS-CoV2 (COVID-19) Diagnosis in Human Saliva by MALDI-TOF MS Profiling Coronavirus disease 19 infection MALDI-TOF MS profiling alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Direction Centrale du Service de Sante des Armees 2020-08-31 2022-08-31 2020-COVID19-15, CoviDiagMS, NCT04460638 Phase Not Applicable Not yet recruiting 0 24 Months 600 Emilie JAVELLE, MD, Lionel ALMERAS, PhD 2020-07-11
Identification Of Ace2 And Tmprss2 Polymorphisms In Malaysian Covid-19 Patients Coronavirus disease 19 infection National Institutes of Health Malaysia Ministry of Health, Malaysia Malaysia 2020-08-01 2021-12-31 55175, NMRR-20-1406-55175 Phase Not Applicable Status not specified 1 17 Months ZARINA BINTI MOHD ZAWAWI 2020-07-10
REEAP COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Malaysia Ministry of Higher Education Malaysia 2020-08-03 2020-12-31 55258, NMRR-20-1393-55258 Phase Not Applicable Status not specified 17 4 Months Dr Valerie Shang Chui Moi 2020-07-10
Reduction of COVID 19 Transmission to Health Care Professionals Coronavirus disease 19 infection Blood group determination alone, Probactiol Plus alone, gel agglutination technique alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Brugmann University Hospital Belgium 2020-04-14 2020-12-31 CHUB-BDS-COVID19, NCT04462627 Phase Not Applicable Recruiting 1 8 Months 500 Francis Corazza, MD, Hanane El Kenz, MD 2020-07-10
Lanadelumab in Participants Hospitalized With COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia lanadelumab alone Plasma kallikrein inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Takeda Pharmaceutical Co Ltd Takeda Development Center Americas, Inc 2020-07-19 2020-09-30 NCT04460105, TAK-743-1002 Phase 1b Clinical Not yet recruiting 0 2 Months 24 Study Director, Takeda Development Center Americas (TDCA) Contact 2020-07-10
Prevention, Efficacy and Safety of BCG Vaccine in COVID-19 Among Healthcare Workers Coronavirus disease 19 infection BCG vaccine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Universitario Dr. Jose E. Gonzalez Mexico 2020-07-06 2021-01-01 EN20-00011, NCT04461379 Phase 3 Clinical Not yet recruiting 1 5 Months 908 René Rodríguez- Gutiérrez, Dr. MSc., René Rodríguez-Gutiérrez, René Rodríguez-Gutiérrez, Dr.MSc. 2020-07-10
A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Orally Inhaled Aerosolized Hydroxychloroquine Sulfate in Healthy Adult Volunteers Coronavirus disease 19 infection hydroxychloroquine sulfate alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Pulmoquine Therapeutics, Inc Rockefeller University US 2020-06-25 2020-09-15 NCT04461353, PUL-01 Phase 1 Clinical Recruiting 1 2 Months 16 Ohad S Bentur, MD, MHA, Robert S Hillman, PhD 2020-07-10
A trial to evaluate Clungene SARS-CoV-2 Virus (COVID-19) IgG/IgM Rapid Test Cassette to reveal the presence of COVID-19 antibodies Coronavirus disease 19 infection Clungene SARS-CoV-2 Virus (COVID-19) IgG/IgM Rapid Test Cassette alone Proven Pharmaceuticals LLC US Phase Not Applicable Planned 1 2020-07-09
ONCOVID-AURA: Excess Risk of Morbi-mortality Due to COVID-19 in Patients With Cancer Coronavirus disease 19 infection, Hematological neoplasm, Solid tumor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospices Civils De Lyon France 2020-06-15 2021-02-15 69HCL20_0509, NCT04457570, ONCOVID-AURA Phase Not Applicable Recruiting 5 8 Months 600 BAY Jacques Olivier, MD, Botelho-Nevers Elisabeth, PR, CALATTINI Sarah, FOURNEL Pierre, MD, PEROL David, Pr, PERRON Julien, MD 2020-07-10
Psychological Preparedness towards Novel Coronavirus (COVID-19) among Old Age Home Staff - an online survey Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chinese University of Hong Kong Hong Kong 2020-07-08 2021-07-07 ChiCTR2000034537 Phase Not Applicable Not yet recruiting 1 12 Months 500 Allen Ting Chun LEE, Linda Chiu Wa LAM 2020-07-10
Covid19TmeSer: Forecast Number of Covid-19 Cases Worldwide Coronavirus disease 19 infection ARIMA model buliding alone, ARIMA model validation alone, Hyndman-Khandakar algorithm alone Turkish Ministry of Health Izmir Teaching Hospital Turkey 2019-12-31 2020-06-20 Covid19TmeSer, NCT04460274, TURKISHMOHITH-TIMESERIES Phase Not Applicable Completed 1 5 Months 7882471 Serhat Akay, Principal Investigator 2020-07-10
Hidden COVID-19 infection in Hong Kong Coronavirus disease 19 infection Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Health and Health Services Research Fund Hong Kong 2020-05-15 2021-05-14 ChiCTR2000034522 Phase Not Applicable Recruiting 1 12 Months 3000 Prof. Paul KS Chan 2020-07-10
Effect of Ayurveda medicinein Covid-19 mild symptoms Coronavirus disease 19 infection Variable regimens including AYUSH 64 , Dashamula Kwatha , Pathyadi Kwatha , Sansamani Vati , Trikatu Churna , Yastimadhu Ghanavati Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Ayush Govt of Gujarat India 2020-07-15 CTRI/2020/07/026433 Phase 2 Clinical Not yet recruiting 1 25 Vd Falgun Patel, Vd Shital Bhagiya, Vd Surendra Soni, VdDilip Jani 2020-07-10
DASS COVID-19: DASS COVID-19 Coronavirus disease 19 infection Muar Hospital Malaysia 2020-07-05 2020-09-30 55600, DASS COVID-19, NMRR-20-1379-55600 Phase Not Applicable Status not specified 1 2 Months Dr Khalifah Nabilah Binti Mashar 2020-07-10
Remdesivir for the Treatment of COVID-19: A Scoping Review Coronavirus disease 19 infection remdesivir alone COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Institute For Medical Research (Inc In Malaysia) Malaysia 2020-07-24 2020-08-24 55660, NMRR-20-1369-55660 Phase Not Applicable Status not specified 1 1 Month Nor Soleha binti Mohd Dali, dr Nor Asiah Muhamad 2020-07-10
COVID-19SWD: COVID-19 Surveillance Based on Smart Wearable Device Coronavirus disease 19 infection smart wearable device alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Peking University First Hospital China 2020-07-01 2021-03-10 2020055-0615, COVID-19SWD, NCT04459637 Phase Not Applicable Not yet recruiting 1 8 Months 200 Cheng Zhang, Chunbo Zhang, Fangfang Guo, Guangfa Wang, Guangfa Wang, MD., Hong Zhang, Jing Ma, Jiping Liao, PhD., Yunxia Wang, Zhu Tian 2020-07-10
Coagulation Changes Associated With COVID-19 Infection Coronavirus disease 19 infection Quantra QPlus system alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hemosonics Llc US 2020-07-27 2020-11-12 HEMCS-035, NCT04460664 Phase Not Applicable Not yet recruiting 1 3 Months 50 Deborah A Winegar, PhD 2020-07-10
Treatment of Coronavirus COVID-19 Pneumonia (Pathogen SARS-CoV-2) With Cryopreserved Allogeneic P-MMSCs and UC-MMSCs Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia mechanical ventilation alone, supportive therapy alone, Оxygen therapy alone, Variable regimens including Cryopreserved placenta-derived multipotent mesenchymal stromal cell , azithromycin , ceftriaxone , dexamethasone , enoxaparin sodium Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Institute of Cell Therapy, Ukraine Kyiv City Clinical Hospital # 4 Ukraine 2020-05-02 2021-12-31 #4/24.04.2020, NCT04461925 Phase 1/Phase 2 Clinical Recruiting 1 19 Months 30 Alexey Chibisov, MD, Alina Ustymenko, PhD, Peter Nemtinov, MD 2020-07-10
Open-label, Non-comparative Trial of the Combination of Hydroxychloroquine and Azithromycin in the Treatment of Hospitalized Patients Coronavirus disease 19 infection, Lower respiratory tract infection azithromycin plus hydroxychloroquine Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of New Mexico US 2020-03-24 2025-03-24 20-156, NCT04458948 Phase 2 Clinical No longer recruiting 1 60 Months 10000 Cristina Beato 2020-07-10
A Phase II clinical trial of EIDD-2801 for the treatment of COVID-19 Coronavirus disease 19 infection EIDD-2801 alone RNA polymerase inhibitor Liverpool School of Tropical Medicine, Ridgeback Biotherapeutics LP, The University of Liverpool, University Of Southampton UK Phase 2 Clinical Recruiting 1 Professor Saye Khoo 2020-07-10
Rapid, Onsite COVID-19 Detection Coronavirus disease 19 infection biological sampling alone, rapid onsite COVID-19 testing alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Wisconsin-Madison AIDS Vaccine Research Lab, National Institutes of Health US 2020-07-31 2021-07-31 2020-0855, 5P51OD011106-59, A536300, NCT04460690, PROTOCOL VERSION 6/29/2020, SMPH/PATHOL-LAB MED/ANAT PATH Phase Not Applicable Not yet recruiting 1 12 Months 5000 David O'Connor, PhD, Kristi L Hall 2020-07-10
Administration of Allogenic UC-MSCs as Adjuvant Therapy for Critically-Ill COVID-19 Patients Coronavirus disease 19 infection, Leukopenia, Lymphocytopenia, Viral pneumonia Variable regimens including allogenic umbilical cord mesenchymal stem cells , azithromycin , oseltamivir Exo-alpha sialidase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Indonesia Indonesia 2020-07-31 2020-09-30 ISMMSCCOVID19, NCT04457609 Phase 1 Clinical Recruiting 5 2 Months 40 Adhrie Sugiarto, MD, Ceva W Pitoyo, MD, Cleopas M Rumende, MD, PhD, Dita Aditianingsih, MD, PhD, Erlina Burhan, MD, PhD, Faisal Matondang, MD, Isabella K Liem, MD, PhD, Ismail H Dilogo, MD, PhD, Navy GHM Lolong Wulung, MD, Pompini A Sitompul, MD, RR D Handayani, MD, Radiana D Antarianto, MD, PhD, Rosa Marlina, MD, Telly Kamelia, MD, Titi Sundari, MD, Tri Kurniawati, BSc, Triya Damayanti, MD, PhD, Wahju Aniwidyaningsih, MD 2020-07-10
Association of Comorbidities With COVID-19 Autoimmune disease, Cancer, Cardiovascular disease, Collagen disease, Coronavirus disease 19 infection, Diabetes mellitus, End stage renal disease, Hypertension, Liver disease, Lung disease, Obesity, Vascular disease realtime PCR alone Assiut University Egypt 2020-07-20 2020-11-20 COVID19, NCT04459390 Phase Not Applicable Not yet recruiting 1 4 Months 100 Hebatallah Hassan 2020-07-09
One Year Follow-ups of Patients Admitted to Spanish Intensive Care Units Due to COVID-19 Coronavirus disease 19 infection Centro De Investigación Biomédica En Red De Enfermedades Hepáticas Y Digestivas (Ciberehd) Barcelona Supercomputing Center - Centro Nacional De Supercomputación, Instituto de Salud Carlos III Spain 2020-05-08 2021-05-31 CIBERESUCICOVID, NCT04457505 Phase Not Applicable Recruiting 30 12 Months 5000 Adrian A Ceccato, PhD., Adrián Ceccato, MD, Alejandro Rodriguez, MD, Amalia MARTINEZ DE LA GÁNDARA, MD, Ana Loza, MD, Ana Ortega Montes, MD, Angel Sanchez, Antoni Torres, Antoni Torres, PhD, Arturo Huerta Garcia, MD, Demetrio Carriedo, MD, Dolores Vila Fernández, MD, Elena BUSTAMANTE MUNGUIRA, MD, Elena Gallego, MD, Ferran Roche, MD, Guillermo Muñiz, MD, Ignacio Martinez, Jesús Caballero, MD, Jordi Riera, MD, José M Añon Elizalde, MD, Juan López Messa, MD, Lorenzo Socías Crespí, MD, Mari C de la Torre, MD, Maria L Martinez, MD, Nieves Carbonell, MD, Pablo Vidal Cortes, MD, Pedro Lara, MD, Rafael Máñez Mendiluce, Ricard Ferrer, MD, Ruth Jorge Garcia, Sergio Ossa, MD, Susana Sancho, MD, Victor Sagredo, MD 2020-07-10
SUROCO: Surgical Outcomes in Covid Patients - the SUROCO, Multicenter, Cohort Study (COVID-19) Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia surgical procedure alone Centre hospitalier de l'Université de Montréal (CHUM) CHU de Quebec-Universite Laval, Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Centre for Research of CHUS (CRCHUS), Hopital Du Sacre-Coeur De Montreal, Hopital Maisonneuve-Rosemont, Montreal Heart Institute, Research Institute of the McGill University Health Centre Canada 2020-03-13 2021-04-13 19.386, NCT04458337, SUROCO Phase Not Applicable Recruiting 1 13 Months 120 François-Martin Carrier, MD, FRCPC, Julie Desroches, PhD, Monique Ruel, RN, CCRP 2020-07-11
Part Two of Novel Adoptive Cellular Therapy With SARS-CoV-2 Specific T Cells in Patients With Severe COVID-19 Coronavirus disease 19 infection, Dyspnea, Lung disease, Multiple organ failure, Respiratory failure, Septic shock SARS-CoV-2 specific T cells alone Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) KK Women's and Children's Hospital Changi General Hospital Singapore, Duke-NUS Graduate Medical School, National University Hospital (Singapore) Pte Ltd, Sengkang General Hospital, Singapore General Hospital Pte Ltd Singapore 2020-07-01 2022-12-31 COVID-T 2.0, NCT04457726 Phase 1/Phase 2 Clinical Recruiting 5 30 Months 18 Jiashen Loh, Lip Kun Tan, Michaela Seng, Roshni Sadashiv Gokhale, Wing Hang Leung, Yeh Ching Linn 2020-07-10
Sofosbuvir With and Without Ribavirin in Treatment of COVID 19 Coronavirus disease 19 infection Standard of card treatment alone, sofosbuvir alone, ribavirin plus sofosbuvir Hepatitis C virus NS5B polymerase inhibitor Tanta University Egypt 2020-08-01 2021-08-31 NCT04460443, SOFOSBUVIR Phase 2/Phase 3 Clinical Not yet recruiting 1 13 Months 60 Marwa Salama, Consultant, Sherief Abd-Elsalam, Ass. Prof. Tropical Medicine, Sherief Abd-Elsalam, ass. prof., sherief abd-elsalan, ass. prof. 2020-07-10
Effect of eating habits and exposure to light on sleep, emotion, memory and headache in college students during the COVID-19 pandemic Acute stress disorder, Cognitive disorder, Coronavirus disease 19 infection, Depression, Headache Adjusting sleep habits alone Young Adults (18-44 yrs) Universidade Federal de Pernambuco Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Brazil 2020-06-29 32360720.4.0000.5208, 4.101.968, RBR-5kkpg6, U1111-1253-9533 Phase Not Applicable Not yet recruiting 1 2100 Mirian Celly Medeiros Miranda David, Rhowena Jane Barbosa de Matos 2020-07-10
COVID-AGP: Risk of infection with SARS-CoV-2 amongst physicians Coronavirus disease 19 infection aerosol generating procedures alone Amsterdam UMC, Universitair Medisch Centrum Utrecht Netherlands 2020-06-16 2021-07-16 COVID-AGP, METC-protocolnummer- 20-407/C, NL8735 Phase Not Applicable Not yet recruiting 1 13 Months 3000 Jennifer Breel 2020-07-10
Reducing the risk of COVID-19 spread in hospitals, by stopping droplets from spreading Coronavirus disease 19 infection dental rubber dam alone, fluorescein alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Queen Alexandra Hospital, University of Portsmouth UK 2020-06-15 2022-03-01 IRAS 285515, ISRCTN10378358 Phase Not Applicable Not yet recruiting 1 20 Months 400 Prof. Richard Newsom 2020-07-10
DEFINE: Investigating potential new therapies for COVID-19 Coronavirus disease 19 infection GB-0139 plus nafamostat mesilate Galectin-3 inhibitor Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) NHS Lothian, University of Edinburgh LifeArc UK 2020-002230-32, DEFINE Phase 2 Clinical Recruiting 1 Annya Bruce 2020-07-10
Effect of Allicin derivatives capsule in treatment of patients with new Coronavirus Coronavirus disease 19 infection Standard treatment alone, allicin derivative capsule alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Mashhad University of Medical Sciences Samisaz Pharmaceutical company Iran 2020-06-21 IR.MUMS.REC.1399.289, IRCT20200610047722N1 Phase 0 Clinical Recruiting 1 100 Amir Masoud Hashemian, Hossein Nik Tale, Saeedeh Ebrahimpour 2020-07-11
Effects of SVF and exosome in COVID-19 patients with acute respiratory distress syndrome Coronavirus disease 19 infection, Respiratory distress syndrome SVF separator (Lipogems) alone, Variable regimens including SVF autologous , SVF autologous fluid , blood exosome Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Tabriz University of Medical Sciences Iran 2020-06-30 1399.095.IR.TBZMED.VCR.REC, IRCT20200510047385N1 Phase 2/Phase 3 Clinical Recruiting 1 60 Dr ata mahmoodpor, leila Roshangar, mehdi yosefi, mohammad samiei 2020-07-10
Convalescent Plasma in Pediatric COVID-19 Coronavirus disease 19 infection Standard COVID-19 therapy alone, convalescent plasma (CP) alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Emory University US 2020-07-31 2022-06-30 NCT04458363, STUDY00000789 Phase 0 Clinical Recruiting 1 23 Months 50 Preeti Jaggi, MD 2020-07-10
Treatment of lung lesions with autologous stem cells in patients recovered from COVID-19 (COVID-19) Coronavirus disease 19 infection autologous stem cells alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Instituto de Hematología e Inmunología, Ministerio de Salud Publica Cuba 2020-05-05 2020-12-15 RPCEC00000322 Phase 2 Clinical Recruiting 1 7 Months 20 Consuelo Macias Abraham 2020-07-10
Acute Kidney Injury and Renal Outcomes for COVID-19 Patients in Intensive Care Units Coronavirus disease 19 infection, Renal injury Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospices Civils De Lyon France 2020-04-01 2020-11-30 COV-AKI_2020, NCT04459975 Phase Not Applicable Recruiting 1 8 Months 200 Denis FOUQUE, Professor, Maxime EPSI, Maxime ESPI 2020-07-10
Transfusion with convaling plasma immunizes the asymptomatic patient with Covid infection 19 that for > 30 days is positive SARS CoV-2 PCR (COVID-19) Coronavirus disease 19 infection plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Instituto de Hematología e Inmunología Ministerio de Salud Publica Cuba 2020-05-05 2020-10-12 RPCEC00000323 Phase 2 Clinical Recruiting 1 5 Months 22 Consuelo Macias Abraham 2020-07-10
PLAVID-TRIAL: Effect of COVID-19 convalescent plasma produced by HEMOPE: A randomized study, with a comparative group in several centers Coronavirus disease 19 infection convalescent plasma therapy alone, local standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidade de Pernambuco Science and Technology of the State of Pernambuco Brazil 2020-07-01 31400920.2.0000.5192, 4.100.150, PLAVID-TRIAL, RBR-7jqpnw, U1111-1254-0612 Phase 3 Clinical Not yet recruiting 1 220 Democritus of Barros Miranda Filho 2020-07-11
NACOVID: The Nitazoxanide Plus Atazanavir for COVID-19 Study Coronavirus disease 19 infection Standard of Care alone, atazanavir + ritonavir plus nitazoxanide Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Obafemi Awolowo University African Centre of Excellence for Genomics of Infectious Diseases, Oyo State Ministry of Health, The University of Liverpool Nigeria 2020-08-01 2020-12-31 NACOVID, NACOVID2020, NCT04459286 Phase 2 Clinical Not yet recruiting 1 5 Months 98 Adeniyi Olagunju, PhD, Adeola Fowotade, MBBS, Olabode Ladipo, MBBS 2020-07-09
Project H-COVID: Evaluating Hyper-Brief, Online Materials During the COVID-19 Pandemic Anxiety disorder, Coronavirus disease 19 infection Contain COVID Anxiety SSI alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Stony Brook University Hospital 2020-07-31 2020-08-31 IRB2020-00204, NCT04459455, Project H-COVID Phase Not Applicable Not yet recruiting 0 1 Month 500 Michael Mullarkey, M.A. 2020-07-09
W-SUDs for COVID-19 Coronavirus disease 19 infection Woebot Substance Use Disorder alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Woebot Labs Inc Stanford University US 2020-06-22 2020-08-31 56439, NCT04460027 Phase Not Applicable Recruiting 1 2 Months 160 Judith Prochaska 2020-07-09
Effect of Availability of COVID-19 Testing on Choice to Isolate and Socially Distance Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of California Los Angeles US 2020-07-31 2020-07-31 IRB-20-000980, NCT04459520 Phase Not Applicable Not yet recruiting 1 690 Daniel M Croymans, MD, Daniel M. Croymans 2020-07-09
SCOUT-2: SARS-CoV-2 immune response in asymptomatic patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Amsterdam UMC Netherlands 2020-06-01 2021-06-01 METC 2020_138, NL8733, SCOUT-2 Phase Not Applicable Recruiting 1 12 Months 75 Annemieke van den Broek 2020-07-11
COVID-19 Vaccine Messaging Randomized, Controlled Trial, Part 1 Coronavirus disease 19 infection Anger message alone, Baseline message alone, Community interest message alone, Control message alone, Economic benefit message alone, Economic freedom message alone, Embarrassment message alone, Guilt message alone, Not bravery message alone, Personal freedom message alone, Self-interest message alone, Trust in science message alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Yale University 2020-07-03 2020-07-31 COVIDVACCINEPERSUASION1, NCT04460703 Phase Not Applicable Not yet recruiting 0 4000 2020-07-09
Efficacy of Intranasal Probiotic Treatment to Reduce Severity of Symptoms in COVID19 Infection Coronavirus disease 19 infection Probiorinse alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Centre hospitalier de l'Université de Montréal (CHUM) Canada 2020-07-07 2020-12-31 249512, NCT04458519, PROBCO Phase Not Applicable Not yet recruiting 1 5 Months 40 Leandra Mfuna Endam, MSc, Martin Y Desrosiers, MD 2020-07-09
Therapeutic Plasma Exchange in Resistant Cytokine Storm of COVID 19 Coronavirus disease 19 infection Therapeutic Plasma Exchange (TPE) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Alexandria Egypt 2020-07-20 2020-12-29 NCT04457349, PLASMA EXCHANGE IN COVID 19 Phase Not Applicable Not yet recruiting 1 5 Months 10 Akram M Fayed, MD, Ayman I Baess, MD, Ehab M El Reweny, MD, Mohamed Mamdouh Elsayed, MD, Nermine H Zakaria, MD, montasser M zeid, MD 2020-07-11
PRANA: A Study to Evaluate OP-101 (Dendrimer N-acetyl-cysteine) in Severe Coronavirus Disease 2019 (COVID-19) Patients Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory tract infection OP-101 alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Orpheris Inc US 2020-07-01 2020-11-10 NCT04458298, OP-101-004, PRANA Phase 2 Clinical Recruiting 1 4 Months 24 H. Bryant Nguyen, MD, Jeffrey L. Cleland, Executive Chair, Co-founder 2020-07-09
NeuroSARS: Neurological Features of SARS COV 2 Infection Ageusia, Bradycardia, Confusion, Coronavirus disease 19 infection, Epilepsy, Hypertension, Hypotension, Hypothermia, Inappropriate ADH syndrome, Movement disorder, Sensory disorder, Tachycardia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre d'Investigation Clinique et Technologique 805 France 2020-03-08 2020-09-30 BRAIN COVID, NCT04460599, NeuroSARS Phase Not Applicable Recruiting 1 6 Months 30 DAVID ORLIKOWSKI, MD PHD, David Orlikowski, MD PhD, Eric Azabou, MD, Isabelle Bossard, Marie Christine Durand, MD, Robert Carlier, MD PHD, david orlikowski, Professor 2020-07-09
COPID19: COVID-19 in PID Survey Coronavirus disease 19 infection, Immune deficiency Imagine Institute France 2020-03-15 2022-03-31 COPID19, COPID19, NCT04459689 Phase Not Applicable Recruiting 1 24 Months 200 Hassan FAOUR, BS, Nizar MAHLAOUI, MD, MPH, PhD 2020-07-09
COFICS: COVID-19 Follow-up Intensive Care Studies Coronavirus disease 19 infection, Respiratory distress syndrome Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Medical Center Groningen Hanze University of Applied Sciences Netherlands 2020-07-01 2022-02-01 COFICS, COFICS201800422, NCT04460170 Phase Not Applicable Not yet recruiting 1 19 Months 100 I van der Meulen, PhD, Willem Dieperink 2020-07-09
Psychiatric Disturbances and COVID-19 Infection Anxiety disorder, Coronavirus disease 19 infection, Depression, Psychiatric disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cairo University Ministry of Health and Population, National Hepatology & Tropical Medicine Research Institute Egypt 2020-06-08 2020-09-15 15-2020/1, NCT04459403 Phase Not Applicable Recruiting 3 3 Months 200 Hend I Shousha, M.D, Rabab Maher, M.D, Shaima Afifi, M.D, Shaimaa Afifi, M.D, amr Abdelazeem, MSc, basem elsayed, M.D, mohamed elkassass, M.D 2020-07-10
PHENOTYPE: Phenotyping patients Admitted to Hospital With covid-19 Infection and identifying Prognostic markers Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chelsea & Westminster NHS Trust UK 2020-06-19 2023-06-30 C&W20/035, NCT04459351, PHENOTYPE Phase Not Applicable Recruiting 1 36 Months 500 Pallav Shah, Pallav Shah, MBBS, MD, Research Delivery Operations Manager 2020-07-10
Pulmonary rehabilitation in individuals affected by Covid-19 Coronavirus disease 19 infection Aerobic exercises alone, Health education alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Midwestern University Brazil 2020-06-06 31798320.4.0000.0106, 4,059,561, RBR-4wnx2q, U1111-1254-1089 Phase Not Applicable Recruiting 1 152 Christiane Riedi Daniel 2020-07-10
Anxiety Level and Oral Hygiene Practice in Dental Students During COVID-19 Pandemic Anxiety disorder, Coronavirus disease 19 infection Healthy volunteers accepted Cairo University Egypt 2020-07-01 2020-09-30 MAI ZAKARIA 4, NCT04460469 Phase Not Applicable Recruiting 1 3 Months 1500 Basma Elsaadany, Ph, Mai Zakaria, Ph 2020-07-09
A Study of Combination Therapies to Treat COVID-19 Infection Coronavirus disease 19 infection Variable regimens including azithromycin , hydroxychloroquine , lopinavir , ritonavir Cytochrome P450 3A4 inhibitor, HIV protease inhibitor, HIV-1 protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) ProgenaBiome Big Corona Ltd US 2020-07-31 2021-12-31 NCT04459702, PRG-043 Phase 2a Clinical Not yet recruiting 1 17 Months 200 Jordan Daniels, MS, Sabine Hazan, MD, Thomas Borody, MD, PhD, 2020-07-09
COVISPERM: Detection of COVID-19 (SARS-CoV-2) in the Semen of COVID+ Patients (Positive RT-PCR on a Nasopharyngeal Swab) Coronavirus disease 19 infection RT-PCR alone Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) GCS Ramsay Santé pour l’Enseignement et la Recherche France 2020-05-07 2021-08-31 2020-A01206-33, COVISPERM, NCT04460534 Phase Not Applicable Recruiting 1 15 Months 100 Lucie DELAROCHE, Pharm D, Pierre OGER, MD 2020-07-09
Healthcare Renunciation During the Confinement Period in Connection With the COVID-19 Epidemic in Adult Emergency Departments Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Angers France 2020-08-31 2021-01-31 49RC20_0155, NCT04460196 Phase Not Applicable Not yet recruiting 2 5 Months 900 DRCI Promotion Interne, Delphine DOUILLET 2020-07-09
A trial to assess safety and efficacy of erythropoietin in the treatment of Covid-19 Coronavirus disease 19 infection erythropoietin alone Max-Planck Gesellschaft zur Förderung Der Wissenschaften eV Phase Not Applicable Planned 0 2020-07-08
Using Tocilizumab in critically ill patients with COVID-19 Coronavirus disease 19 infection Tocilizumab alone, organic support therapy alone, standard intensive care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Universitario Antonio Pedro Brazil 2020-03-16 4.059.207, CAAE 29496920.8.0000.5262, RBR-3zdynp, U1111-1252-7966 Phase 2 Clinical Recruiting 1 60 Victor Côrtes Pourchet de Carvalho 2020-07-10
COVID-19 Breath Test Coronavirus disease 19 infection NBT system alone, breath test alone, nanotechnology biomarker tagging (NBT) alone Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ancon Technologies Ltd UK 2020-06-29 2021-06-14 2020ATL01, NCT04459962 Phase Not Applicable Recruiting 1 11 Months 250 Freda M Gomes, Isaac John, PhD, Linda Pomeroy, PhD, Stephen Winchester, MBBS, MSc 2020-07-09
Study to Assess Efficacy and Safety Relative to Standard of Care in Patients With COVID-19 Pneumonia Coronavirus disease 19 infection, Lung disease, Renal disease, Viral pneumonia ANG-3777 alone, standard of care alone Hepatocyte growth factor receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Angion Biomedica Corp CTI Clinical Trial and Consulting Services Brazil 2020-07-31 2020-10-31 ANG3777-ALI-201, NCT04459676 Phase 2 Clinical Not yet recruiting 7 3 Months 100 Deb Gouveia, John Neylan, MD 2020-07-09
PREPARE-IT: Prevention of COVID-19 With EPA in Healthcare Providers at Risk - Intervention Trial Coronavirus disease 19 infection icosapent ethyl, Amarin alone Apolipoprotein B antagonist, Phospholipase A2 inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Estudios Clinicos Latino America Amarin Pharmaceuticals Inc Argentina 2020-07-31 2020-12-31 NCT04460651, PREPARE-IT, PREPARE-IT. VERSION 1.2 Phase 3 Clinical Not yet recruiting 1 5 Months 1500 Andres Orlandini, MD, Rafael Diaz, MD 2020-07-10
A Phase IIb, Multicenter, Open-label, Randomized, Comparator-Controlled Study to Evaluate the Efficacy and Safety of Desidustat Tablet for the Management of COVID-19 patients Coronavirus disease 19 infection desidustat alone HIF prolyl hydroxylase-2 inhibitor, Prolyl hydroxylase inhibitor Zydus Cadila Healthcare Ltd Phase 2b Clinical Recruiting 0 2020-07-08
SHADE: Short-Term, High-Dose Vitamin D Supplementation for COVID-19 Coronavirus disease 19 infection, Vitamin D deficiency vitamin D alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Postgraduate Institute of Medical Education and Research India 2020-06-15 2020-07-10 121/20, NCT04459247, SHADE Phase Not Applicable Recruiting 1 30 Ashu Rastogi, MD, DM 2020-07-10
Compensatory Reserve Index (CRI) for Management of COVID-19 Coronavirus disease 19 infection CRI management alone, CipherOx CR T1 tablet alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Colorado at Denver and Health Sciences Center Children's Hospital Colorado US 2020-07-31 2021-09-30 20-1406, NCT04457817 Phase Not Applicable Not yet recruiting 1 14 Months 100 Jenny Stevens, MD, Marina Reppucci, MD, Steven L Moulton, MD 2020-07-09
Betadine Effect on Nasal Mucosa Cilia Coronavirus disease 19 infection, Respiratory tract infection povidone-iodine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Boston Medical Center Corp US 2020-08-31 2021-12-31 H-40432, NCT04457765 Phase 0 Clinical Not yet recruiting 1 16 Months 10 Jennifer Shehan, MD, Waleed Ezzat, MD 2020-07-11
An investigator-initiated study to evaluate CK-0802 for the treatment of patients with COVID-19 induced acute respiratory distress syndrome Coronavirus disease 19 infection, Respiratory distress syndrome CK-0802 alone Cellenkos Inc US Phase 2 Clinical Status not specified 1 2 Dr. Douglas Gladstone 2020-07-08
COVID Kids Bavaria: Clinical translational and epidemiological research project on SARS coronavirus 2 infection in during the COVID 19 pandemic children in Bavaria Coronavirus disease 19 infection nasopharynx swab (COVID-19 PCR) alone, questionnaire alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs) Dr. von Hauner Children’s Hospital Bayerisches Staatsministerium für Wissenschaft und Kunst Germany 2020-07-12 20-538, COVID Kids Bavaria, DRKS00022380 Phase Not Applicable Recruiting 1 14000 Anna Kern, Nicole Maison 2020-07-09
FTR-COVID: Respiratory Physiotherapy in Severe COVID-19 Patients Coronavirus disease 19 infection, Hypoxia, Respiratory failure, Viral pneumonia airway clearance alone, early mobilization alone, invasive mechanical ventilation weaning alone, muscle-strengthening exercises alone, non-invasive mechanical ventilation / CPAP alone, oxygen titration alone, respiratory physiotherapy alone, tracheostomy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fondazione IRCCS Ca' Granda-Ospedale Maggiore Policlinico Italy 2020-03-01 2020-07-30 FTR-COVID, FTR-COVID, NCT04459819 Phase Not Applicable Recruiting 1 4 Months 80 Emilia Privitera, MSC, Martina Santambrogio, PhD 2020-07-09
The Prevalence of Pulmonary Hypertension in Patients With COVID-19 Coronavirus disease 19 infection, Pulmonary hypertension echocardiography alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) AttgeNO AB Sweden 2020-06-01 2020-07-10 20200422PA, NCT04459364 Phase Not Applicable Recruiting 1 1 Month 80 Per-Arne Lönnqvist, Professor 2020-07-09
To study the role of zinc combined with standard treatment for COVID-19 Coronavirus disease 19 infection standard treatment alone, zinc sulphate alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Wockhardt Hospitals India 2020-07-11 CTRI/2020/07/026340 Phase Not Applicable Not yet recruiting 1 100 Ramen Goel 2020-07-09
Understanding COVID and cancer Cancer, Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tata Memorial Centre India 2020-07-15 CTRI/2020/07/026339 Phase Not Applicable Not yet recruiting 1 1000 C S Pramesh 2020-07-09
Effectiveness of Measles, Mumps and Rubella Vaccine in Health Care Professionals for COVID-19 Coronavirus disease 19 infection, Viral pneumonia Measles Mumps and Rubella alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dar Al Fouad Hospital Egypt 2020-07-01 PACTR202006883882711 Phase 2 Clinical Not yet recruiting 2 200 Amani El Kholy, Doaa Nagy, Hend Ibrahim, Jehan El Kholy, Mostafa Alfishawy 2020-07-09
A phase I/II clinical trial of ZyCoV-D for the prevention of COVID-19 infection in healthy subjects Coronavirus disease 19 infection ZyCoV-D alone Healthy volunteers accepted Zydus-Cadila Group India 2020-07-31 Phase 1/Phase 2 Clinical Not yet recruiting 1 1000 2020-07-07
Stress and coping among healthcare workers during COVID-19 outbreak Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Sri Ramachandra Institute of Higher Education and Research India 2020-07-15 CTRI/2020/07/026350 Phase Not Applicable Not yet recruiting 1 150 Dr Suvarna Jyothi Kantipudi 2020-07-08
Knowledge, Attitudes and Practices (KAP) Study on COVID-19 in Maryland, Liberia Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Heidelberg Deutsche Forschungsgemeinschaft (DFG), Deutsche Gesellschaft fur Internationale Zusammenarbeit [GIZ] GmbH, German Federal Ministry of Education and Research Liberia 2020-05-28 2020-06-28 DRKS00022371, NREB-APV-014-20, U1111-1254-6575 Phase Not Applicable Completed 1 1 Month 500 Iona Thomas-Connor, Peter Dambach 2020-07-07
Effect of awake proning in patients with COVID-19 related respiratory failure Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure prone positioning alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences India 2020-07-04 CTRI/2020/07/026349 Phase 3 Clinical Recruiting 1 20 Anant Mohan 2020-07-08
Nebulized heparin in patients with mainly moderate coronavirus disease 2019: Randomized controlled trial. COVID-19 Coronavirus disease 19 infection heparin alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Faculty of Medicine, University of Alexandria Egypt 2020-06-15 2020-07-31 PACTR202007606032743 Phase 2 Clinical Recruiting 1 1 Month 100 Amal Mohamed, Dr Rabab S. Mahrous, Tarek Salem, Tarek ismail 2020-07-08
SLKovid: Seroprevalence of SARS-CoV-2 in employees of a clinic with COVID-center (COVID-19) Coronavirus disease 19 infection serological antibody test alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) SLK Klinikum Heilbronn GmbH Zweckgebundene Privatspende Germany 2020-07-01 DRKS00022226, F-2020-085, SLKovid Phase Not Applicable Recruiting 1 5000 Dilyana Vladimirova, Uwe Martens 2020-07-08
LACBSOT: Lagos COVID-19 Black Seed Oil Trial Coronavirus disease 19 infection Black seed oil alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Lagos State Ministry of Health Nigeria 2020-09-01 2020-10-23 LACBSOT, PACTR202007611764617 Phase Not Applicable Not yet recruiting 1 1 Month 80 AbdulWasiu Busari, Hussein AbdurRazzaq, Ibrahim Oreagba 2020-07-08
Ayurvedic Rasayana treatment as an add-on therapy to improve the results in management of coronavirus disease Coronavirus disease 19 infection standard of care therapy alone, Pranvir plus Yashada Rasayana Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Yashwantrao Chavan Memorial Hospital India 2020-07-11 AR/RC/T-01, CTRI/2020/07/026343 Phase Not Applicable Not yet recruiting 1 200 Dr Avinash Kadam, Dr Mahesh Asalkar 2020-07-09
RDC19: Clinical features of patients with rheumatic diseases and COVID-19 infection in Sarawak, Malaysia Coronavirus disease 19 infection, Musculoskeletal disease Sarawak General Hospital Malaysia 2020-07-03 2020-07-31 55569, NMRR-20-1362-55569, RDC19 Phase Not Applicable No longer recruiting 1 Dr Sharifah Aishah bt Wan Mohamad Akbar 2020-07-09
Evaluation of the effect of sofosbuvir/daclatasvir in COVID-19 patients Coronavirus disease 19 infection lopinavir + ritonavir plus sofosbuvir + daclatasvir HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Abadan University of Medical Sciences Iran 2020-07-08 IR.ABADANUMS.REC.1399.071, IRCT20200624047908N1 Phase 3 Clinical Recruiting 2 600 Gholamali Eslami 2020-07-09
Rapid response Covid-19 Bera district Coronavirus disease 19 infection PEJABAT KESIHATAN DAERAH BERA Malaysia 2020-06-04 2020-08-04 55363, NMRR-20-1357-55363 Phase Not Applicable Status not specified 1 2 Months DR MOHAMMAD LOKMAN HAKIM BIN MAT ISAR, Wan Intan Fairouza Binti Wan Shahibi 2020-07-09
Effect of vitamin D supplementation in COVID-19 Coronavirus disease 19 infection vitamin D (ZAHRAVI ) plus vitamin D syrup (Pharmacology Mashhad University of Medical Sciences) Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Mashhad University of Medical Sciences Iran 2020-06-21 IR.MUMS.REC.1399.237, IRCT20110726007117N11 Phase 3 Clinical Recruiting 1 210 Doctor Majid Ghayour Mobarhan, Doctor Mohsen Tafaghodi, Zahra Khorasanchi, ِDoctor Majid Ghayour Mobarhan 2020-07-08
Clinical trial of ozone therapy in mild to moderate Covid-19 subjects Coronavirus disease 19 infection ozone therapy alone, standard care alone Lokmanya Tilak Municipal Medical College and General Hospital India 2020-07-13 CTRI/2020/07/026354, MHC/CT/20-21/005 Phase 1/Phase 2 Clinical Not yet recruiting 1 60 Dr Jignasha Captain, Dr Mili Shah 2020-07-08
The efficacy and safety of mesenchymal stem cell transplantation in patients with COVID-19 pneumonia Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory tract infection, Viral pneumonia routine treatment alone, umbilical core-derived mesenchymal stem cell transplantation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hamadan University of Medical Sciences Iran 2020-07-22 IR.UMSHA.REC.1399.330, IRCT20200426047206N2 Phase 3 Clinical Not yet recruiting 1 30 Salman Khazaei, Sara Soleimani Asl, Sara Soleimani asl 2020-07-08
Effect of Thalidomide in Covid-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia hydroxichloroquine plus thalidomide (Ibn Sina Company) Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Isfahan University of medical Sciences Iran 2020-05-09 IR.MUI.MED.REC.1399.048, IRCT20200428047232N1 Phase 3 Clinical No longer recruiting 1 60 Samane Pourajam, Samane pourajam, Shaghayegh Haghjoo 2020-07-08
Giloy Gomutra Capsule, Asthi churna aur Kamdhenu Asava ka vaishvik mahamari Covid-19 par Ayurvedic Research Coronavirus disease 19 infection Variable regimens including Asthi Churna , Giloy gaumutra Capsule , Kamdhenu Asava Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Bansi Gir Gaushala 2020-07-12 CTRI/2020/07/026353 Phase 2 Clinical Not yet recruiting 0 30 Dr Dineshchandra Pandya, Dr Urvi Pandya 2020-07-08
Software for COVID19 Detection from Chest X-Ray, CT or Ultrasonography Coronavirus disease 19 infection CT or Ultrasonography alone, Chest X-Ray alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kalinga Institute of Medical Sciences India 2020-07-14 CTRI/2020/07/026351 Phase Not Applicable Not yet recruiting 1 1000 Abhishek Biswas, Dr Nirmal Mohakud 2020-07-08
Study to assess the Health care workers’ knowledge of the Medical cause of death certification for COVID-19 related deaths in cancer patients Coronavirus disease 19 infection teaching intervention alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Tata Memorial Centre India 2020-07-13 CTRI/2020/07/026338 Phase Not Applicable Not yet recruiting 1 90 Divya Khanna 2020-07-09
The Covid-19 Study with Ayurveda add-on to ICMR Guideline Coronavirus disease 19 infection Ayurveda formulations alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Government Stanley Medical College Hospital, Ministry of Ayush India 2020-07-11 CTRI/2020/07/026337 Phase 2/Phase 3 Clinical Not yet recruiting 1 36 Dr P Balaji, Dr Somit Kumar, Sujith Subash Eranezhath 2020-07-08
Kabasura Kudineer, Shakti drops and Turmeric plus in the management of COVID-19 Coronavirus disease 19 infection allopathic medicines alone, Variable regimens including Kabasura kudineer , Shakti Drops , Turmeric plus Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Sriveda Sattva PvtLtd India 2020-07-13 CTRI/2020/07/026371 Phase 3 Clinical Not yet recruiting 1 30 Dr M Ravi Kumar Reddy, Dr Ranganatha R 2020-07-09
A Mixed Method Comparative Study on Coping Mechanisms among Covid-19 Nursing Frontliners from Three Different Units (ICU,HDU and Wards) in Klang Valley Government Hospitals Coronavirus disease 19 infection Kolej Universiti Antarabangsa PICOMS Malaysia 2020-08-01 2021-01-30 NMRR-20-1340-55214 Phase Not Applicable Not yet recruiting 1 5 Months NORHANAZA BINTI MOHD YUNOS 2020-07-08
Evaluation of the performance of rapid diagnostic kit (COVIDAB-SP) in the detection of COVID-19 virus antibody Coronavirus disease 19 infection COVIDAB-SP alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Capital Health Services India Pvt Ltd India 2020-07-14 CTRI/2020/07/026370 Phase Not Applicable Not yet recruiting 1 2000 Dr R Arunkumar 2020-07-09
Knowledge and Behaviors toward Antibiotics Use and Infection Prevention Coronavirus disease 19 infection Hospital Raja Permaisuri Bainun Malaysia 2020-07-01 2020-12-31 NMRR-20-1336-55250 Phase Not Applicable Status not specified 1 6 Months Chang Chee Tao, Ms Thong Kah Shuen 2020-07-08
Evaluation of the performance of rapid diagnostic kit (COVIDAG-SP) in the detection of COVID-19 virus antigen Coronavirus disease 19 infection COVIDAG-SP Kit alone, Naso Pharyngeal swab, Saliva and Serum sample alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Capital Health Services India Pvt Ltd India 2020-07-14 CTRI/2020/07/026369 Phase Not Applicable Not yet recruiting 1 500 Dr R Arunkumar 2020-07-08
The association between the neutralizing activity and the amount of antibody in the convalescence stage of SARS-CoV-2 infection: A multicenter, observational study Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Yokohama City University Japan Agency for Medical Research and Development Japan 2020-08-17 UMIN000041021 Phase Not Applicable Not yet recruiting 1 140 Atsushi Goto, Takeharu Yamanaka 2020-07-09
A prospective, open-label, single-arm multicenter pilot study to evaluate the effect off-label use of tocilizumab (TCZ) in hospitalized adult patients with severe COVID-19 Coronavirus disease 19 infection tocilizumab alone University of Turin Phase 2 Clinical Status not specified 0 63 2020-07-07
Spread of corona virus disease and factors affecting it in Pune city Coronavirus disease 19 infection questionnaire alone Healthy volunteers accepted, Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Byramjee Jeejeebhoy Govt Medical College and Sassoon General Hospitals Health Department Pune Municipal Corporation Pune India 2020-07-13 CTRI/2020/07/026368 Phase Not Applicable Not yet recruiting 1 700 Dr Ganesh Jagdale, Dr Malangori Parande 2020-07-08
Evaluation Of The Efficacy of AYUSH KWATH in The Prevention of COVID-19 Coronavirus disease 19 infection ayush kwath alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Dr.S R.Rajasthan Ayurved University Jodhpur India 2020-07-14 CTRI/2020/07/026355 Phase Not Applicable Not yet recruiting 1 500 Prof Dr Abhimanyu Kumar 2020-07-08
VERARE: Effectiveness of Virtual Motor Actions for Improving Walking in Patients With Post-resuscitation Muscle Weakness Coronavirus disease 19 infection, Muscle weakness haptic stimulation alone, headphone alone, sensory feedback alone, soothing music therapy alone, vibrator alone, virtual headset alone, virtual reality actions alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rennes University Hospital INRIA Institut National de Recherche en Informatique et en Automatique France 2020-08-01 2023-08-01 2020-A01722-37, 35RC20_8897_VERARE, NCT04441164, VERARE Phase Not Applicable Not yet recruiting 1 36 Months 510 Mélanie COGNE, MD 2020-07-08
Spanish PICNIC: A Randomized, Open-Label Clinical Study Evaluating the Impact of EnteraGam, a Nutritional Intervention Containing Bovine Plasma-Derived Immunoglobulin CoNcentrate, on Clinical Outcomes In People with COVID-19 Coronavirus disease 19 infection EnteraGam alone, standard of care alone Entera Health Spain Spanish PICNIC Phase Not Applicable Not yet recruiting 1 420 Netanya Utay 2020-07-07
Multicenter, open, prospective, randomized, comparative study to study the safety and efficacy of the drug Fabivirin (INN: favipiravir), film-coated tablets 200 mg (Pharmasintez JSC, Russia) in the treatment of patients hospitalized with COVID-19 Coronavirus disease 19 infection favipiravir alone RNA polymerase inhibitor Pharmasyntez Russian Federation 2020-06-26 2021-01-01 FAVPR-2020/I Phase 3 Clinical Status not specified 23 6 Months 200 2020-07-07
A 3D Telemedicine During COVID-19: Non-clinical Validation Coronavirus disease 19 infection 3D Telemedicine alone Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) NHS Greater Glasgow and Clyde Jean Brown Bequest Fund, Glasgow UK 2020-07-31 2021-01-31 GN20HS287, NCT04444297 Phase Not Applicable Not yet recruiting 1 6 Months 40 2020-07-09
Prevalence of Mental Health Problems Among Undergraduate Students at the Universidad de Los Andes Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression, Drug dependence, Suicidal ideation Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidad de los Andes, Chile Ministerio de Educación, Chile Chile 2020-08-03 2020-12-31 FDI UAN1901, NCT04447690 Phase Not Applicable Not yet recruiting 1 4 Months 3869 Francisco J Díaz Zenteno, MBBS, Francisco J Solorza Flores, MBBS, Gabriel A Lorca Osorio, MBBS, Jorge Gaete, Jorge Gaete Olivares, MD, PhD, José M Valdés Valdés, José M Valdés Valdés, BA, José M Valdés Valdés, MBBS, Matías Alvear Violic, MBBS, Pascale M Christiansen Barrio, MBBS 2020-07-07
Considering the administration of Desferral supplementary and Vitamin C on the ferritin levels of COVID-19 patients Coronavirus disease 19 infection, Viral infection desferal deodorant Baduz plus vitamin C Shahid Beheshti University of Medical Sciences, Laser Application in Medical Sciences Research Center Iran 2020-02-20 IR.SBMU.RETECH.REC.1399.256, IRCT20190121042444N3 Phase 3 Clinical Recruiting 1 78 Faranak Behnaz, Nahid Asadi, Seyed Ebrahim Sadeghzadeh Sadat 2020-07-07
A Phase I clinical trial of SARS-CoV-2 inactivated viral vaccine (COVID-19), Panacea Biotec/ Refana for the treatment of COVID-19 Coronavirus disease 19 infection SARS-CoV-2 inactivated viral vaccine (COVID-19), Panacea Biotec/ Refana alone Panacea Biotec Ltd 2020-10-31 Phase 1 Clinical Planned 0 2020-07-06
The experiences of nurses hospitalized with novel coronavirus pneumonia (COVID-19) in China: a qualitative study Summary Coronavirus disease 19 infection, Viral pneumonia Interview using WeChat video alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Union Hospital Tongji Medical School Huazhong University Of Science & Technology China 2020-05-27 2020-06-15 ChiCTR2000034433 Phase Not Applicable No longer recruiting 1 15 Prof. Liu Yilan, Tan Xuan 2020-07-07
Novel coronavirus pneumonia (COVID-19) Prevention and Control Strategy - Development of multi-layer Network Early Warning System Coronavirus disease 19 infection, Viral pneumonia Xinhua Hospital Chinesisch-Deutsches Zentrum fuer Wissenschaftsfoerderung China 2020-10-01 2021-09-30 ChiCTR2000034359 Phase 0 Clinical Not yet recruiting 1 12 Months 6000 Yang Ling 2020-07-07
A clinical trial of plitidepsin for potential treatment of acute Respiratory Distress Syndrome (ARDS) in hospitalized COVID-19 pneumonia patients Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia plitidepsin alone Elongation factor 1 alpha 2 modulator, VEGF-1 receptor modulator Boryung Pharm Co Ltd South Korea 2020-09-30 Phase Not Applicable Planned 1 2020-07-06
Plasma exchange in COVID-19 patients Coronavirus disease 19 infection, Inflammatory disease Variable regimens including colloidal solution (albumin and fresh frozen plasma) , convalescent plasma , plasma exchange Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Shahid Beheshti University of Medical Sciences, Laser Application in Medical Sciences Research Center Iran 2020-06-21 IR.SBMU.MSP.REC.1399.118, IRCT20200416047099N2 Phase 2 Clinical Recruiting 1 10 Abbas Hajifathali, Elham Roshandel, Haniye Ghaffari-nazari, Nasrin khateri 2020-07-08
A clinical trial of BNT-162a1 for potential treatment of COVID-19 infection Coronavirus disease 19 infection BNT-162a1 alone BioNTech SE, Pfizer Inc Phase 3 Clinical Planned 0 30000 2020-07-06
A multi-site clinical trial of COVID-19 vaccine for potential treatment of COVID-19 infection Coronavirus disease 19 infection COVID-19 vaccine alone Zydus Cadila Healthcare Ltd India Phase 2 Clinical Planned 1 1000 2020-07-06
A retrospective, case series study to illustrate [18F]-FDG-PET/CT findings in patients affected by cancer with clinical diagnosis of Covid-19 A retrospective study to illustrate [18F]-FDG-PET/CT findings in patients affected by cancer with clinical diagnosis of Covid-19 Coronavirus disease 19 infection PET/CT scan alone, [18F]-FDG alone Fondazione IRCCS Istituto Nazionale Tumori Italy Phase Not Applicable Status not specified 1 5 2020-07-06
A clinical trial of StemVacs for potential treatment of COVID-19 infection Coronavirus disease 19 infection StemVacs, Emvolio alone Therapeutic Solutions International Inc Phase Not Applicable Planned 0 2020-07-06
ESPRIMO: Intervention for Young Adults With Multiple Sclerosis Coronavirus disease 19 infection, Multiple sclerosis, Psychiatric disorder ESPRIMO intervention alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Azienda Ospedaliera Universitaria Integrata Di Verona Italy 2020-05-13 2022-08-31 2676CESC, ESPRIMO, NCT04431323 Phase Not Applicable Recruiting 1 27 Months 60 Alberto Gajofatto, Alberto Gajofatto Study Principal Investigator, Alberto Gajofatto, MD, PhD, Alina Klonova, Annamaria Ghellere, M.Sc., Doriana Rudi, Federico Schena, MD, PhD, Francesca Gobbin, MD, Francesca Vitali, PhD, Isolde M Busch, M.Sc., Lidia del Piccolo, PhD, Maria Angela Mazzi, PhD, Michela Rimondini, Michela Rimondini, PhD, Valeria Donisi, PhD 2020-07-06
RECOVER-19: Rehabilitation Needs and Functional Recovery in Covid-19 Acute and Post-acute Care Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universita Politecnica delle Marche Italy 2020-07-01 2021-06-30 NCT04456036, NEUROREHABAN_COVID_2020, RECOVER-19 Phase Not Applicable Not yet recruiting 1 12 Months 100 Elisa Andrenelli, MD PhD, Maria Gabriella Ceravolo, MD PhD, Marianna Capecci, Marianna Capecci, MD PhD 2020-07-06
COVIPLEX: Plasma exchange in severe COVID19 infection Coronavirus disease 19 infection OctaplasLG alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University College London UK 2020-06-25 132796, 2020-002668-29, COVIPLEX Phase 2 Clinical Recruiting 1 40 2020-07-08
Combined Endophthalmitis and Orbital Cellulitis in Patients With Novel Coronavirus Disease (COVID-19) Cellulitis, Coronavirus disease 19 infection, Endophthalmitis Minia University Egypt 2020-04-27 2020-06-30 NCT04456556, OCULAR INFECTION IN COVID19 Phase Not Applicable Completed 1 2 Months 5 Mohamed Farouk Sayed Othman Abelkader 2020-07-06
Study on the Recovery of Pulmonary Function, Chest CT, Hematological and Immune and Inflammatory Conditions in COVID-19 Rehabilitation Patients Coronavirus disease 19 infection, Hematological disease, Immune disorder, Inflammatory disease, Pulmonary fibrosis lung CT imaging alone, lung function test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Wuhan Union Hospital, China China 2020-06-19 2022-06-01 NCIP03, NCT04456101 Phase Not Applicable Recruiting 1 23 Months 240 Juanjuan Xu, professor, Yang Jin, MD, Yang Jin, professor 2020-07-06
Intermediate-size, Expanded Access Program (EAP), Mesenchymal Stromal Cells (MSC) for Multisystem Inflammatory Syndrome in Children (MIS-C) Associated With Coronavirus Disease (COVID-19) Coronavirus disease 19 infection, Inflammatory disease Variable regimens including cetirizine , hydrocortisone , remestemcel-L Histamine H1 receptor antagonist Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) Mesoblast International Sarl Mesoblast Ltd US MSB-MSC-MISC001, NCT04456439 Phase Not Applicable Recruiting 1 50 Elizabeth Burke, ANP-C, Kenneth M. Borow, MD 2020-07-06
Illness Wellness Scale is a new scale which is being developed to assess the physical performance status of all patients, whether or not suffering from COVID infection, requiring surgical intervention or care Coronavirus disease 19 infection grading system alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences India 2020-07-11 CTRI/2020/07/026330 Phase Not Applicable Not yet recruiting 1 210 Dr Arun Kumar, Dr Yashwant Singh Rathore 2020-07-08
ConPlaS: Survey on Convalescent Plasma (CVP) for COVID-19 Coronavirus disease 19 infection Convalescent Plasma alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences India 2020-07-06 CTRI/2020/07/026331, ConPlaS Phase Not Applicable Not yet recruiting 1 2200 Diptiranjan Rout 2020-07-08
A first-in-human clinical study to assess safety and tolerability of niclosamide in healthy subjects for the treatment of COVID-19 Coronavirus disease 19 infection niclosamide (COVID-19), UNION therapeutics/ Institut Pasteur Korea alone S phase kinase associated protein 2 inhibitor Healthy volunteers accepted UNION therapeutics Denmark Technical University, The Danish National Advanced Technology Foundation, Trial Nation Denmark Denmark Phase Not Applicable Not yet recruiting 2 2020-07-03
Whole-Virion Inactivated SARS-CoV-2 Vaccine (BBV-152) in Healthy Volunteers Coronavirus disease 19 infection COVAXIN alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Bharat Biotech International Ltd India 2020-07-13 BBIL/BBV152-A/2020, CTRI/2020/07/026300 Phase 1/Phase 2 Clinical Not yet recruiting 12 1125 Dr Ajeet Pratap Singh, Dr Amit Suresh Bhate, Dr Chandramani Singh, Dr Chandrasekhar Gillurkar, Dr Jitendra Kushwaha, Dr Prabhakar Reddy, Dr R Vasudev, Dr Sagar Vivek Redkar, Dr Sanjay Kumar Rai, Dr Satyajit Mohapatra, Dr Savita Verma, Dr V Krishna Mohan, Dr Venkata rao 2020-07-09
A phase I trial of COVAXIN for COVID-19 Coronavirus disease 19 infection COVAXIN alone COVID19 Spike glycoprotein modulator Bharat Biotech International Ltd Indian Council of Medical Research, National Institute of Virology India 2020-07-31 Phase 1 Clinical Planned 1 2020-07-10
A Phase III trial of COVID-19 vaccine for COVID-19 patients Coronavirus disease 19 infection COVID-19 vaccine (inactivated, Vero cells/intramuscular), Beijing Biological Products Institute/National Institute for Viral Disease Control and Prevention of Chinese Center for Disease Control and Prevention alone Sinopharm China National Biotech Institute Co Ltd United Arab Emirates Phase 3 Clinical Planned 1 2020-07-03
Atovaquone for Treatment of COVID-19 Coronavirus disease 19 infection atovaquone alone, standard of care therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Texas Southwestern Medical Center US 2020-07-31 2021-03-31 NCT04456153, STU-2020-0707 Phase 2 Clinical Not yet recruiting 1 8 Months 60 Mamta Jain, Mamta Jain, M.D., Tianna Petersen 2020-07-06
A phase IIb/III, global clinical study to assess BNT-162a1, BNT-162b1, BNT-162b2 and BNT-162c2 in healthy subjects Coronavirus disease 19 infection BNT-162a1 alone, BNT-162b1 alone, BNT-162b2 alone, BNT-162c2 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted BioNTech SE, Pfizer Inc 2020-07-31 Phase 2/Phase 3 Clinical Planned 0 30000 2020-07-06
A trial to evaluate MV-014-210 for the prevention of coronavirus infection Coronavirus disease 19 infection MV-014-210 alone COVID19 Spike glycoprotein modulator Meissa Vaccines Inc US Phase Not Applicable Planned 1 2020-07-08
A multicenter, randomized, double-blind, placebo-controlled, phase III clinical trial protocol to evaluate the safety and efficacy of siltuximab plus standard-of-care in hospitalized patients (expected n = 400) with COVID-19 associated ARDS Coronavirus disease 19 infection, Respiratory distress syndrome siltuximab alone, standard of care alone Heat shock protein inhibitor, IL-6 receptor antagonist EUSA Pharma Phase 3 Clinical Not yet recruiting 0 400 2020-07-03
Characteristics of Patients and Healthcare Workers With COVID-19 in Meta State, Colombia Coronavirus disease 19 infection, Respiratory disease standard care alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Departamental De Villavicencio Clínica Meta, Grupo de Investigación de Villavicencio, Spring Medical Clinic, Universidad Cooperativa De Colombia Colombia 2020-07-31 2020-08-31 GRIVI-2020-01COVID, NCT04456426 Phase Not Applicable Not yet recruiting 1 1 Month 250 Emma I Rodríguez, MSc, Norton Perez, Norton Perez, MD 2020-07-06
A clinical study of OPN-019 for the potential treatment of COVID-19 infection Coronavirus disease 19 infection OPN-019 alone Optinose US Inc Phase Not Applicable Planned 0 2020-07-10
PROFISCOV: Clinical Trial of Efficacy and Safety of Sinovac's Adsorbed COVID-19 (Inactivated) Vaccine in Healthcare Professionals Coronavirus disease 19 infection CoronaVac alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto Butantan, Sinovac Biotech Ltd Sinovac Life Sciences Co., Ltd. Brazil 2020-07-31 2021-10-31 COV-02-IB, NCT04456595, PROFISCOV Phase 3 Clinical Not yet recruiting 12 15 Months 8870 André Siqueira, MD, PhD, Eduardo B Coelho, MD, PhD, Eduardo B Coelho, MD,PhD, Esper Kallas, MD,PhD, Fabiano Ramos, MD, Francisco H Aoki, MD, PhD, Fábio E Leal, MD, PhD, Gustavo Adolfo Sierra Romero, MD, PhD, Luis Fernando Aranha Camargo, MD, PhD, Luiz Carlos Pereira Júnior, MD, PhD, Mauro M Teixeira, MD, PhD, Maurício L Nogueira, MD, PhD, PhD, Ricardo Palacios, MD, PhD, Sonia Raboni, MD, PhD 2020-07-08
INFECT-19: Inflammatory Regulation Effect of NAC on COVID-19 Treatment Coronavirus disease 19 infection, Inflammatory disease N-acetylcysteine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) King Saud University Saudi Arabia 2020-08-01 2021-08-30 E-20-4934, INFECT-19, NCT04455243 Phase 3 Clinical Not yet recruiting 1 12 Months 1180 Dr. Tariq Alhawassi, Soundus Atta, PH 2020-07-06
CARDOVID: Cardiac and Thoracic Imaging in Pediatric Patients With Evidence of Systemic Inflammation COVID-19 Linked Cardiogenic shock, Coronavirus disease 19 infection, Inflammatory disease, Myocarditis CT scan alone, MRI alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Imagine Institute France 2020-06-15 2022-06-30 CARDOVID, HJ-20-CARDOVID, NCT04455347 Phase Not Applicable Recruiting 1 24 Months 80 Francesca Raimondi 2020-07-06
Lopinavir/Ritonavir for the Treatment of COVID-19 Positive Patients With Cancer and Immune Suppression in the Last Year Coronavirus disease 19 infection lopinavir + ritonavir alone HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) OHSU Knight Cancer Institute National Cancer Institute, Oregon Health Sciences University US 2020-07-06 2021-07-01 NCI-2020-02877, NCT04455958, P30CA069533, STUDY00021444 Phase 2 Clinical Not yet recruiting 1 11 Months 75 Raymond C Bergan, Raymond C. Bergan 2020-07-06
ECCES: COVID-19 and Chilblains Coronavirus disease 19 infection biological sampling alone Healthy volunteers accepted Rennes University Hospital France 2020-07-15 2020-09-30 35RC20-8888-ECCES, ECCES, NCT04455308 Phase Not Applicable Not yet recruiting 5 2 Months 300 Alain DUPUY, MD, PhD, Emilie BRENAUT, MD, Mahtab SAMIMI, MD, PhD, Sébastien BARBAROT, MD, PhD, Yannick Le Corre, MD 2020-07-06
Use of Mesenchymal Stem Cells in Acute Respiratory Distress Syndrome Caused by COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia Wharton's jelly derived mesenchymal stem cell therapy (iv, ARDS caused by COVID-19), Instituto de Medicina Regenerativa alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto de Medicina Regenerativa Mexico 2020-04-16 2020-09-15 MSC-ARDS-001, NCT04456361 Phase 0 Clinical No longer recruiting 1 5 Months 9 Jesus Perez 2020-07-09
A phase I clinical trial of GC-376 for the treatment of patients with COVID-19 infection Coronavirus disease 19 infection GC-376 alone COVID19 replicase polyprotein 1a inhibitor, COVID19 replicase polyprotein 1ab inhibitor Anivive Lifesciences Inc 2020-12-31 Phase 1 Clinical Planned 0 2020-07-03
Convalescent Plasma as Treatment for Subjects With Early COVID-19 Infection Coronavirus disease 19 infection convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hackensack Meridian Health US 2020-07-31 2021-07-31 NCT04456413, PRO2020-0542 Phase 2 Clinical Not yet recruiting 1 12 Months 306 Mariefel Vendivil, Marlo Kemp, Michele L Donato, MD 2020-07-06
Risk Prediction and Therapy Monitoring in Patients With SARS-Cov-2 Infection/COVID 19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Heidelberg Germany 2020-04-01 2022-04-30 CROWNLESS, NCT04456075 Phase Not Applicable Recruiting 1 25 Months 100 Felix JF Herth, MD, Frederik Trinkmann, MD 2020-07-06
A Trial Looking at the Use of Camostat to Reduce Progression of Symptoms of Coronavirus (COVID-19) in People Who Have Tested Positive But Are Able to Stay at Home Coronavirus disease 19 infection repurposed camostat (COVID-19), University of Tokyo alone Serine protease inhibitor, Trypsin inhibitor Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cancer Research UK Latus Therapeutics UK 2020-07-27 2021-08-31 CRUKD/20/002, NCT04455815 Phase 2/Phase 3 Clinical Not yet recruiting 2 13 Months 389 Kevin Dhaliwal, Professor, Suzie Anthony, Dr 2020-07-10
German Covid-19 ICU Registry Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Tubingen Germany 2020-07-31 2021-12-31 DCIR, NCT04455451 Phase Not Applicable Not yet recruiting 1 17 Months 2000 Harry Magunia, MD, Peter Rosenberger, MD, PhD 2020-07-06
CANADA: Inhaled NO for the Treatment of COVID-19 Caused by SARS-CoV-2 Coronavirus disease 19 infection, Dyspnea LungFit system alone, nitric oxide alone, standard supportive care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Beyond Air Ltd 2020-07-15 2020-12-15 BAI_COV19_01_CAN, CANADA, NCT04456088 Phase 2 Clinical Not yet recruiting 0 5 Months 50 Asher Tal, MD, Meital Hatan, Rinat Kalaora 2020-07-06
COVID_ENZA: Randomized, Open-Label, Phase II Study to Evaluate the Efficacy of Enzalutamide in High-Risk Male Outpatients With COVID-19 Coronavirus disease 19 infection enzalutamide alone, standard of care alone Androgen receptor antagonist, Cytochrome P450 3A4 stimulator, DNA binding protein inhibitor, Prostate specific antigen modulator, Translocation associated protein inhibitor Male, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Osped Italiano Institute For Research In Biomedicine, Institute of Oncology Research (Switzerland), Oncology Institute of Southern Switzerland Switzerland 2020-07-31 2021-12-31 COVID_ENZA, COVID_ENZA, NCT04456049 Phase 2 Clinical Not yet recruiting 1 17 Months 90 Ricardo Pereira Mestre, Ricardo Pereira Mestre, MD 2020-07-06
CoV2_LapSurg: Can the COVID-19 virus be detected in the smoke generated in minimally invasive surgery in patients with confirmed coronavirus infection? Coronavirus disease 19 infection Biosampler (SKC Inc, AMS Analitica) alone, RT-PCR alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Azienda Unita Sanitaria Locale di Reggio Emilia Italy 2020-04-23 2021-06-24 600/2020/OSS/AUSLRE, CoV2_LapSurg, ISRCTN18077365 Phase Not Applicable Recruiting 1 14 Months 20 Dr Maurizio Zizzo, Dr Ruggero Bollino 2020-07-06
NutriCoronaTeen: Lifestyle modification of adolescents from different countries during confinement by Covid-19 Coronavirus disease 19 infection Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) IMDEA Food Spain, Colombia, Chile, Brazil, Italy 2020-04-09 2020-06-19 IMD PI-043, ISRCTN14025343, NutriCoronaTeen Phase Not Applicable Completed 5 2 Months 500 Dr Alberto Davalos, Dr María B. Ruiz-Roso 2020-07-06
Study of Ampion for the Treatment of Adult COVID-19 Patients Requiring Oxygen Supplementation Coronavirus disease 19 infection, Dyspnea Ampion alone, Standard of care alone Aryl hydrocarbon receptor agonist, Stem cell antigen-1 inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ampio Pharmaceuticals Inc US 2020-07-10 2020-11-01 AP-016, NCT04456452 Phase 1 Clinical Not yet recruiting 1 3 Months 10 2020-07-06
Qualitative Study on Self-protection Experience of Medical Staff in the Isolation Area of Novel Coronavirus Pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Self-protection alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Guangdong Provincial Hospital of Chinese Medicine China 2020-04-09 2020-06-15 ChiCTR2000034287 Phase Not Applicable No longer recruiting 1 2 Months 11 Lu Peng 2020-07-07
SARS-CoV2-School Student Study: Prevalence of SARS-CoV2 in scholars: comparison of boarding and private school (COVID-19) Coronavirus disease 19 infection throat swab and a blood sample alone Adolescents (13-17 yrs), Young Adults (18-44 yrs) Landessportverband Baden-Württemberg e. V. (LSV) Germany 2020-05-27 280/20, DRKS00021909, SARS-CoV2-School Student Study Phase Not Applicable Recruiting 1 60 Heidrun Zurmöhle, Peter Deibert 2020-07-08
COVAPEX: COVID-19 in ART: Perception and Experience Coronavirus disease 19 infection, Female infertility, Male infertility assisted reproductive treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) University Hospital, Montpellier France 2020-06-01 2020-07-30 COVAPEX, NCT04456010, RECHMPL20_0351 Phase Not Applicable Recruiting 1 1 Month 600 Noémie RANISAVLJEVIC, M.D., Ph.D, Noémie Ranisavljevic, M.D., Ph.D 2020-07-08
MANFFT-02: Safety and tolerance of manuka honey for use as a nebulizer solution Coronavirus disease 19 infection makula honey alone, nebulizer alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Manukamed Ltd University of Waikato New Zealand 2020-07-13 2020-09-28 ACTRN12620000701921p, MANFFT-02 Phase 1 Clinical Not yet recruiting 1 2 Months 15 Dr Chris McMahon 2020-07-07
Fit testing of N95 filtering facepieces for anesthetists and nurses treating COVID-19 patients Coronavirus disease 19 infection N95 FFP alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Austin Health Australia 2020-06-29 ACTRN12620000702910, U1111-1253-8286 Phase Not Applicable Not yet recruiting 1 60 A/Prof Laurence Weinberg, Dr Caitlin Low 2020-07-07
Laryngectomy during COVID-19 Coronavirus disease 19 infection laryngectomy alone Melaka Hospital Malaysia 2020-07-01 2021-06-30 55502, NMRR-20-1249-55502 Phase Not Applicable Status not specified 1 12 Months Dr MOHAMED ILIYAS BIN SULTAN ABDUL KADER 2020-07-07
Healthcare workers knowledge, perception and compliance to PPE Coronavirus disease 19 infection personal protective equipment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universiti Teknologi Mara Malaysia 2020-08-01 2021-03-31 55226, NMRR-20-1241-55226 Phase Not Applicable Not yet recruiting 2 8 Months 323 Dr Nurul Huda Ahmad 2020-07-07
A Placebo-Controlled Study to Evaluate the effect of the recombinant Bacillus Calmette–Guérin (BCG) vaccine VPM-1002 on the Incidence or Disease Severity of SARS-COV-2/COVID-19 Among High-Risk Participants in Australia Coronavirus disease 19 infection VPM-1002 alone Listeriolysin stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) ACCELAGEN PTY LTD, Serum Institute of India Ltd Australia 2020-06-30 2021-03-30 ACTRN12620000707965 Phase 3 Clinical Not yet recruiting 1 9 Months 3468 A/Prof Mark Bloch, Mr Greg Plunkett 2020-07-07
KAP TandCM: KAP TandCM Coronavirus disease 19 infection Ministry of Health, Malaysia Malaysia 2020-07-06 2020-08-10 55387, KAP TandCM, NMRR-20-1240-55387 Phase Not Applicable Not yet recruiting 1 1 Month none TEH LI YIN 2020-07-07
Telepharmacy, Counseling, Covid-19 Coronavirus disease 19 infection Hospital Sungai Buloh Malaysia 2020-04-20 2020-06-18 55573, NMRR-20-1278-55573 Phase Not Applicable Status not specified 1 1 Month MS KALAIVANI A/P SUBRAMANIAM 2020-07-07
Warning Signs in COVID-19 Patients Coronavirus disease 19 infection Hospital Sungai Buloh Malaysia 2020-08-01 2021-08-01 55360, NMRR-20-1237-55360 Phase Not Applicable Not yet recruiting 1 12 Months Doctor DR Yasmin Mohamed Gani, Dr Syarifah Nurul Ain Bt Syed Badaruddin 2020-07-07
Effectiveness of Convalescent Immune Plasma Therapy Coronavirus disease 19 infection Convalescent Immune Plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bağcılar Training & Research Hospital Turkey 2020-05-15 2020-06-17 2020.05.2.14.070, NCT04442958 Phase Not Applicable Completed 1 1 Month 60 Salih SS Sevdi, Md 2020-07-07
Psychosocial impact of COVID-19 pandemic on health care workers in a tertiary care hospital in MY Coronavirus disease 19 infection Sarawak General Hospital Malaysia 2020-06-25 2020-07-31 55333, NMRR-20-1271-55333 Phase Not Applicable Status not specified 1 1 Month Chuah Jun Sen 2020-07-07
Stellate Ganglion Blockade in COVID-19 Positive Patients Adult respiratory distress syndrome, Coronavirus disease 19 infection Stellate Ganglion Block alone, Variable regimens including Decadron , bupivacaine, AstraZeneca , clonidine Sodium channel inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Nebraska 2020-07-31 2021-07-31 603.20.FB, NCT04445337 Phase Not Applicable Not yet recruiting 0 12 Months 10 2020-07-07
Effect of Physical Therapy Exercises on Cardiorespiratory Fitness Level in COVID19 Patients After Recovery Coronavirus disease 19 infection aerobic training alone, breathing exerises alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Government College University Faisalabad Pakistan 2020-07-03 2020-08-15 313, NCT04445376 Phase Not Applicable Recruiting 2 1 Month 20 Awais Bin Inam, Phd., Ishtiaq Ahmed, Ishtiaq Ahmed, DPT, ishtiaq ahmed 2020-07-10
Ivermectin in the prevention of covid-19 Coronavirus disease 19 infection, Respiratory tract infection ivermectin alone Chloride channel modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) DVFM India 2020-07-10 CTRI/2020/06/026232 Phase 3 Clinical Not yet recruiting 1 50 BKumar 2020-07-07
To study effect of ayurvedic treatment for prevention and management of asymptomatic, mild and moderate cases of COVID-19 Coronavirus disease 19 infection standard of care alone, Variable regimens including Samshamanivati , SitopaladiChurna , Sutshekhar , TribhuvanKirti , black resins , cardamom , cinnamon , ginger , pepper , shunthiksheerpak , turmeric Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Ministry of Ayush SYMBIOSIS INSTITUTE OF HEALTH SCIENCE India 2020-07-15 CTRI/2020/06/026231 Phase Not Applicable Not yet recruiting 1 160 Dr Jyoti Shirodkar, Dr Rajkumar Nikalje 2020-07-07
CASCADE: Measures of Complement Activation and Inflammation in Patients With COVID-19 Coronavirus disease 19 infection, Inflammatory disease, Respiratory failure Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Portsmouth Hospitals NHS Trust Akari Therapeutics Plc UK 2020-05-28 2021-09-30 CASCADE, NCT04453527, PHT/2020/37 Phase Not Applicable Recruiting 1 16 Months 100 Anoop J Chauhan, Anoop J Chauhan, PhD 2020-07-06
Neuropathology in Adults Intensive Care Unit Patients With COVID-19 Brain injury, Coronavirus disease 19 infection autopsy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universite De Versailles-St Quentin En Yvelines France 2020-03-10 2020-05-15 NCT04453670, OBS2020 Phase Not Applicable Completed 1 2 Months 7 Djillali Annane, Djillali annane 2020-07-04
CHAT: The California Home Abortion by Telehealth (CHAT) Study Abortion, Coronavirus disease 19 infection counseling alone, mifepristone alone, telehealth consultation alone Estradiol 17 beta dehydrogenase stimulator, Glucocorticoid receptor antagonist, Progesterone receptor antagonist Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of California San Francisco California Latinas for Reproductive Justice, UCGHI Women's Health, Gender, and Empowerment Center of Expertise US 2020-11-30 2022-10-31 19-29437, CHAT, NCT04432792 Phase 2 Clinical Not yet recruiting 1 23 Months 700 Karen Meckstroth, MD, Ushma Upadhyay, PhD, MPH 2020-07-08
A clinical trial of Ayurveda formulations in COVID-19 Coronavirus disease 19 infection Variable regimens including Ashtadashang Ghana Vati  , Malla Chandrodaya , Parijata swaras Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Banaras Hindu University Ministry of Ayush India 2020-07-10 CTRI/2020/06/026229 Phase 2 Clinical Not yet recruiting 1 100 Dr Namrata Joshi 2020-07-07
A Study on Unani regimen for prevention of high/moderate risk population of COVID 19 Coronavirus disease 19 infection Khameera Marwareed alone, Tiryaq-e-Arba alone, Variable regimens including Behidana (Cydonia oblonga) , Sapistan (Cordia myxa) , Unnab (Zizyphus jujube) Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Central Council for Research in Unani Medicine India 2020-07-07 CCRUM 04/06/2020/, CTRI/2020/06/026227 Phase 3 Clinical Not yet recruiting 1 60 Dr Naheed Parveen, Dr Pradeep Kumar, Prof Asim Ali Khan 2020-07-07
Study to Evaluate STI-1499 (COVI-GUARD) in Hospitalized Patients With COVID-19 Coronavirus disease 19 infection, Lung infection COVI-GUARD alone, standard of care alone COVID19 Spike glycoprotein inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sorrento Therapeutics Inc 2020-08-31 2021-01-31 NCT04454398, STI-1499-1001 Phase 1 Clinical Not yet recruiting 0 5 Months 24 Andreas G Niethammer, MD PhD, Ying Yan 2020-07-04
FAP-REA: FilmArray and Management of ICU Patients With Pneumonia in the Covid-19 Context Coronavirus disease 19 infection, Respiratory disease, Viral pneumonia FilmArray alone, PCR test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Hospital, Nancy, France Centre Hospitalier Universitaire de Reims 2020-07-01 2020-08-30 2020PI101, FAP-REA, NCT04453540 Phase Not Applicable Not yet recruiting 0 1 Month 150 2020-07-04
Tele-Wellness Supported App for Family Child Care Home Providers and Families to Promote Health, Family Engagement, and School Readiness Amid COVID-19 Acute stress disorder, Coronavirus disease 19 infection family child care home (FCCH) alone Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Johns Hopkins University US 2020-07-31 2021-07-31 IRB00250864, NCT04453657 Phase Not Applicable Not yet recruiting 1 12 Months 270 Kimberly Hill, MS, Lucine Francis, PhD 2020-07-10
Hexoskin Feasibility Study With COVID-19 Patients Coronavirus disease 19 infection Hexoskin smart shirt alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hexoskin Canada 2020-07-15 2020-12-15 HEXOSKIN COVID-19 STUDY, NCT04453891 Phase Not Applicable Not yet recruiting 1 5 Months 16 Maria Strifas Athanassiou, MSc, Nguyen Thu Ngan Trinh, Nguyen Thu Ngan Trinh, PhD 2020-07-04
Bariatric Surgery During Lockdown, Impact of COVID-19 on Physical and Mental Health Coronavirus disease 19 infection, Obesity bariatric surgery alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Rome Tor Vergata Italy 2020-03-09 2020-05-30 NCT04453579, UNROMEB Phase Not Applicable Completed 1 2 Months 116 paolo gentileschi, MD 2020-07-03
Delay study COVID Kuching Coronavirus disease 19 infection PEJABAT KESIHATAN BAHAGIAN KUCHING Malaysia 2020-06-30 2020-07-31 55365, NMRR-20-1299-55365 Phase Not Applicable No longer recruiting 1 1 Month Dr Andrew Kiyu, Dr MICHEAL PELITINI ANAK UGAK, doctor GREGORY A/L JOSEPH XAVIER 2020-07-07
Monovalent Recombinant COVID19 Vaccine (COVAX-19) Coronavirus disease 19 infection Covax-19 alone Coronavirus spike glycoprotein inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Vaxine Pty Ltd Central Adelaide Local Health Network Inc Australia 2020-06-30 2021-07-01 13110, NCT04453852 Phase 1 Clinical Recruiting 1 12 Months 40 David Gordon, MBBS, Ph.D, David Gordon, MBBS, PhD, Guy Ludbrook, MBBS, Kathy Heyman, Nikolai Petrovsky, MBBS, Ph.D, Pravin Hissaria, MBBS. PhD 2020-07-10
AtTAC: Impact of Tissue Plasminogen Activator (tPA) Treatment for an Atypical Acute Respiratory Distress Syndrome (COVID-19) Coronavirus disease 19 infection, Lung embolism, Respiratory distress syndrome, Respiratory failure Variable regimens including alteplase , heparin , low molecular weight heparin , unfractionated heparin Tissue plasminogen activator stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Negovsky Research Institute of General Reanimatology Sklifosovsky Institute of Emergency Care 2020-07-01 2020-11-01 AtTAC, NCT04453371, TPA-2020 Phase 3 Clinical Not yet recruiting 0 4 Months 50 Valery Likhvantsev 2020-07-04
Examining COVID-19 death cases in Kuching Sarawak. A public health case-control study Coronavirus disease 19 infection PEJABAT KESIHATAN BAHAGIAN KUCHING Malaysia 2020-06-30 2020-07-31 55371, NMRR-20-1287-55371 Phase Not Applicable Status not specified 1 1 Month Dr Andrew Kiyu, Dr MICHEAL PELITINI ANAK UGAK v, doctor GREGORY A/L JOSEPH XAVIER 2020-07-06
AZITHROVID: Anti Infective Agents Impact in COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia azithromycin alone, azithromycin plus hydroxychloroquine Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre d'Investigation Clinique et Technologique 805 France 2020-03-02 2020-04-25 AZITHROVID, AZITHROVID, INDS, NCT04453501 Phase Not Applicable Completed 1 1 Month 132 2020-07-03
SARSCoV2CZImun: Antibody Detection in COVID-19 Cured Patients (SARS-CoV-2-CZ-Immunity) Coronavirus disease 19 infection SARS-CoV-2 diagnostic rapid test alone, blood sampling alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institute of health information and statistics of the Czech Republic Institut Klinické a Experimentální Medicin, MasaryKuv Onkologicky Ustav, Masaryk University, Ministry of Health, Czech Republic, National Institute of Public Health, Prague, St. Anne's University Hospital Brno, Czech Republic, University Hospital Brno Czech Republic 2020-05-18 2020-06-03 NCT04453280, SARSCoV2CZImun, UZIS 2020/2 Phase Not Applicable Completed 1 695 Dalibor Valík, Prof., Jarmila Razova, M.D., Ph.D., Ladislav Dusek, Prof., Roman Prymula, Prof. 2020-07-03
POLYCOR: Study to Evaluate the Safety and Efficacy of XAV-19 in Patients With COVID-19 Induced Moderate Pneumonia Coronavirus disease 19 infection, Viral pneumonia XAV-19 alone COVID19 Spike glycoprotein inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) CHU De Nantes, Xenothera Bpifrance France 2020-07-06 2021-09-30 NCT04453384, POLYCOR, RC20_0230 Phase 2 Clinical Not yet recruiting 4 14 Months 368 Benjamin GABORIT, Florence ADER, François RAFFI, Karine LACOMBE, Vincent DUBEE 2020-07-03
Is COVID-19 Transmitted Through Human Milk? Implications for Breastfeeding and Human Milk Banking-Study 1a Coronavirus disease 19 infection breastmilk sampling alone Healthy volunteers accepted Hospital for Sick Children Sinai Health System, University of Toronto Canada 2020-05-24 2021-01-31 39373-A, NCT04453969 Phase Not Applicable Recruiting 2 8 Months 50 Deborah L O'Connor, PhD RD, Deborah O'Connor, Sharon Unger, MD 2020-07-03
The Assessment of the Prevalence, Clinical Course and Treatment of COVID-19 Complications Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder complex diagnostic panel alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Silesian Center for Heart Diseases Slaski Uniwersytet Medyczny w Katowicach Poland 2020-06-08 2021-11-30 COVID-19 COMPLICATIONS STUDY, NCT04453748 Phase Not Applicable Recruiting 1 17 Months 200 Mariusz Gasior 2020-07-07
Clinical Characteristics and Outcomes of 187 Critically Ill Patients With Coronavirus Disease 2019 (COVID-19) Coronavirus disease 19 infection corticosteroid therapy alone, heparin alone, hydroxychloroquine alone, tocilizumab alone Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Sao Domingos Brazil 2020-07-15 2020-11-30 COVID-19 ICU, NCT04454372 Phase Not Applicable Not yet recruiting 1 4 Months 187 JOSE AZEVEDO, MD, JOSE R AZEVEDO, MD, PhD, José Raimundo Araujo de Azevedo 2020-07-03
At Home Monitoring for Patients With Covid-19 Coronavirus disease 19 infection Covidfreeathome app alone, pulse oximeter alone, smart watch alone, thermometer alone The University Health Network Sunnybrook Health Sciences Centre, University of Toronto Canada 2020-07-07 2023-04-30 3185, NCT04453774 Phase Not Applicable Not yet recruiting 2 33 Months 1000 Robert Wu, Tatiana Son 2020-07-08
Safety and Efficacy of Tramadol in COVID-19 Egyptian Patients Coronavirus disease 19 infection, Respiratory disease tramadol hydrochloride alone Opioid receptor mu agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Tanta University Egypt 2020-07-31 2020-10-31 NCT04454307, TRAM/COVID19 Phase 1/Phase 2 Clinical Not yet recruiting 1 3 Months 100 Nahla Elashmawy, PhD 2020-07-03
An international, multicenter clinical trial to evaluate BDB-1 for the treatment of patients with coronavirus disease 19 infection Coronavirus disease 19 infection BDB-1 alone Complement C5a factor inhibitor Staidson (Beijing) Biopharmaceutical Co Ltd India Phase Not Applicable Planned 1 2020-07-02
COVID-19 in Pain Perspective Anxiety disorder, Coronavirus disease 19 infection, Depression, Myalgia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sisli Etfal Hospital Turkey 2020-06-03 2020-06-20 2811, NCT04454333 Phase Not Applicable Completed 1 466 Aylin Ayyıldız, MD 2020-07-07
A phase III clinical trial of using Celltex's TRUECELL Mesenchymal Stem Cells (MSCs) to treat severe COVID-19 symptoms Coronavirus disease 19 infection, Lung disease, Respiratory disease, Viral pneumonia TRUECELL Mesenchymal Stem Cells alone Celltex Therapeutics Corp, Hospital Juarez de Mexico Mexico Phase 3 Clinical Recruiting 1 2020-07-02
CICERO- A Care Home Study of COVID-19 Coronavirus disease 19 infection Q16 testing alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Queen Mary University of London UK 2020-07-02 2020-09-28 285524, NCT04453553 Phase Not Applicable Not yet recruiting 1 2 Months 50 Joanne Martin 2020-07-03
Clinical Trial to Evaluate the Efficacy of RUTI Against SARS- COV-2 Infection in Healthcare Workers Coronavirus disease 19 infection RUTI alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundació Institut Germans Trias i Pujol Spain 2020-07-10 2020-12-31 NCT04453488, RUTICOVID19 Phase 1 Clinical Not yet recruiting 2 5 Months 315 Pere-Joan Cardona, Pere-Joan Cardona, MD, PhD 2020-07-03
Effect of COVID-19 Pandemic on Perceived Stress, Anxiety, Mood, and Training Quality in Elite Athletes Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs) Üsküdar Üniversitesi New York Medical College Turkey 2020-05-27 2020-12-31 61351342/ 2020-286, NCT04453566 Phase Not Applicable Recruiting 1 7 Months 200 IHSAN Y balkya, MD, Ihsan Balkaya, Ihsan Y Balkaya, MD, Mesut Karahan, PhD, Numan M Ocal, PT 2020-07-03
The New Silicone N99 Half-Piece Respirator Coronavirus disease 19 infection MT-05U machine alone, filtration test alone, fit test alone, silicone N99 half-piece respirator alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Bangkok Metropolitan Administration Medical College and Vajira Hospital Thailand 2020-05-01 2020-05-31 053/2563, NCT04454606 Phase Not Applicable Completed 1 1 Month 43 Thananda Trakarnvanich, M.D. 2020-07-03
Intravenous Immunoglobulin Therapy in the Treatment of Moderate Pneumonia in COVID-19 patients Coronavirus disease 19 infection, Viral pneumonia Variable regimens including Pantocid , azithromycin , immunoglobulin , lopinavir + ritonavir , paracetamol , piperacillin + tazobactam (injectable), Wyeth/Toyama/Taiho Beta lactamase inhibitor, HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Virchow Biotech Pvt Ltd India 2020-06-29 CTRI/2020/06/026222, VB-N-IVIG-COVID-19/2020-CT2 Phase 2 Clinical Not yet recruiting 6 100 Aditi, Dr Anil Kumar, Dr Arun Dewan, Dr D Himanshu, Dr Giridhar Patil, Dr R S Raman, DrHemanth Nandigala, DrVijay Barge 2020-07-08
Is COVID-19 Transmitted Through Human Milk? Implications for Breastfeeding and Human Milk Banking: Study 1b Coronavirus disease 19 infection donor human milk sampling alone Healthy volunteers accepted Hospital for Sick Children Sinai Health System, University of Toronto Canada 2020-06-21 2021-02-28 39373-B, NCT04453982 Phase Not Applicable Recruiting 1 8 Months 500 Deborah L O'Connor, PhD RD, Deborah O'Connor, Sharon Unger, MD 2020-07-03
Intervention of Ayurvedic Medicine (Arogya Kashayam) in Covid-19 positive cases (Asymptomatic and Mild Symptomatic) Coronavirus disease 19 infection Arogya Kashayam-20 alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Ministry of Ayush India 2020-07-01 CTRI/2020/06/026221 Phase 2 Clinical Recruiting 1 370 Prof Umesh Shukla 2020-07-07
Cytokine and Eicosanoid Mediators in Coronavirus Disease 2019 (COVID-19) Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) EicOsis LLC US 2020-07-31 2021-04-30 EC1153-2-01, NCT04452942 Phase Not Applicable Not yet recruiting 1 9 Months 30 Ana Mavarez-Martinez, MD, Irene Cortes-Puch, MD, Sergio Bergese, MD 2020-07-08
RLF-100 (Aviptadil) Individual Patient Expanded Access Coronavirus disease 19 infection, Respiratory failure aviptadil (inhaled, sarcoidosis/acute lung injury/acute respiratory distress syndrome associated COVID-19), Relief Therapeutics Holding alone Adrenergic receptor antagonist, VIP receptor agonist Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) NeuroRx Inc Cavendish Impact Foundation, Global Emerging Markets Fund, Impact Assets, Inc., Relief Therapeutics Holding AG US NCT04453839, RLF-100_IPEA Phase Not Applicable Recruiting 4 Daniel D Yeh, MD, Daniel H Kett, MD, Dushyanatha Jayaweera, MD, Dushyantha Jayaweera, MD, Jihad Georges Youssef, MD, Jonathan C Javitt, MD, MPH, Rainer Lenhardt, MD, Richard Lee, MD, Robert E Besthof, MIM 2020-07-03
Pulmonary embolism and/or deep vein thrombosis in COVID-19 patients Coronavirus disease 19 infection, Deep vein thrombosis, Lung embolism computed tomography alone, doppler ultrasound alone, echocardiography alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Zollernalb Klinikum Balingen Germany 2020-05-18 DRKS00021604, F-2020-066 Phase Not Applicable Recruiting 1 100 Erwin Biecker 2020-07-08
Investigating the effect of sweet almond on symptoms of COVID-19 Coronavirus disease 19 infection, Respiratory disease sweet almond product intake alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shaheed Beheshti Medical University Iran 2020-06-30 IR.SBMU.NRITLD.REC.1399.120, IRCT20180712040446N2 Phase 3 Clinical Recruiting 1 60 Ali Abdolahinia, Atefe Sharif, Mohammad Kamalinejad 2020-07-03
Psychological intervention to improve the mental health of patients with COVID-19 Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection WeChat app alone, and-washing technique alone, breath meditation alone, cognitive behavioral therapy alone, music therapy alone, self-monitoring COVID-19 related symptoms alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Bengbu Medical College China 2020-02-01 2020-03-22 ISRCTN68675756 Phase Not Applicable Completed 1 1 Month 93 Prof Li 2020-07-03
Efficacy of Bacmune (MV-130) in the Prevention of Disease Due to COVID-19 Infection in Healthcare Personnel (Bacmune) Coronavirus disease 19 infection Bacmune alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Inmunotek SL BioClever 2005 SL Mexico 2020-07-31 2021-12-31 MV130-SLG-037, NCT04452643 Phase 3 Clinical Not yet recruiting 3 17 Months 3312 Blanca Nohemí Zamora Mendoza, Blanca Zamora Mendoza, MD, Felipe Monrroy López, Felipe Monrroy López, MD, Miguel Casanovas, Rosaura Esperanza Benitez Pérez, Rosaura Esperanza Benitez Pérez, MD 2020-07-03
The role of metronidazole in COVID-19 Coronavirus disease 19 infection, Viral pneumonia metronidazole alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shaheed Beheshti Medical University Iran 2020-05-31 IR.SBMU.RETECH.REC.1399.157, IRCT20200608047686N1 Phase 2 Clinical No longer recruiting 1 30 Afshin Zarghi, Muhanna Kazempour 2020-07-03
A phase II/III clinical trial of T-COVID for the treatment of patients with COVID-19 infection Coronavirus disease 19 infection T-COVID alone Altimmune Inc Phase 2/Phase 3 Clinical Planned 0 2020-07-01
A phase I/II, randomized, double-blind, placebo-controlled clinical trial of T-COVID to prevent clinical worsening in patients with early COVID-19 Coronavirus disease 19 infection T-COVID alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Altimmune Inc Medical Technology Enterprise Consortium, US Army Medical Research and Development Command US 2020-07-31 Phase 1/Phase 2 Clinical Not yet recruiting 1 100 Dr. Michael Yin 2020-07-02
Study of International Clinical Data Collection, Doctor to Doctor Telemedicine, education, and AI platform against deterioration of COVID-19 Coronavirus disease 19 infection AI platform alone, Doctor to Doctor Telemedicine alone, education alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Jikei University Japan Agency for Medical Research and Development Japan, Europe, South America 2020-06-20 UMIN000040409 Phase Not Applicable Not yet recruiting 1 1000 Makoto Kawai 2020-07-02
A seroprevalence study of COVID-19 in IBD patients Coronavirus disease 19 infection immunomodulative therapy alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hyogo College of Medicine Japan 2020-09-01 UMIN000040838 Phase Not Applicable Not yet recruiting 3 2000 Kenji Watanabe 2020-07-05
UNICODE: Epidemiological, Clinical, Molecular Characteristics of Hospital Employees With or Without COVID-19 Infection Adult respiratory distress syndrome, Coronavirus disease 19 infection, Lung disease, Sepsis biological sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Istituto Clinico Humanitas Italy 2020-06-01 2023-06-01 NCT04451577, UNICODE, UNICODE Phase Not Applicable Recruiting 1 36 Months 5000 Maria Rescigno, PhD 2020-07-02
The Impact of COVID-19 Pandemic on Critical Limb Threatening Ischemia and Emergency Vascular Practice Coronavirus disease 19 infection, Ischemia Mansoura University Egypt 2020-05-25 2020-06-21 NCT04452682, R.20.06.898 - 2020/06/16 Phase Not Applicable Completed 1 998 2020-07-02
SchuCo: Study on the Evaluation of the Infectious Process of SARS-CoV-2 in Teachers and Students in Saxony (COVID-19) Coronavirus disease 19 infection biological sampling alone University of Leipzig Deutsche Forschungsgemeinschaft (DFG), German Federal Ministry of Education and Research, Sächsisches Staatsministerium für Kultus Germany 2020-05-27 260/20-ek, DRKS00022032, SchuCo Phase Not Applicable Recruiting 17 4000 Anne Jurkutat, Wieland Kiess 2020-07-02
SARS-CoV-2 Exposure and Psychological Well-being of Health Care Workers in a German Department of Anesthesiology During the COVID-19 Pandemic Coronavirus disease 19 infection, Psychiatric disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitätsklinikum Würzburg Klinik und Poliklinik für Anästhesiologie Germany 2020-04-24 73/20, DRKS00021649 Phase Not Applicable Recruiting 1 100 Benedikt Schmid 2020-07-02
Grief counseling in family members of the COVID-19 victims Coronavirus disease 19 infection Grief counseling session alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Iran University of Medical Sciences Iran 2020-06-06 IR.IUMS.REC.1399.272, IRCT20200505047305N1 Phase Not Applicable Recruiting 9 120 Dr. Mahdiyeh Salehi, Dr. Marjan Fathi, Dr. Morteza Naserbakht, Dr. Noushin Khademoreza, Dr. Seyed Abbas Motevalian, Mr. Ali Asadi 2020-07-02
Safety of Short-term Hydroxychloroquine Plus Azithromycin Treatment in Critically Ill Patients With Severe COVID-19 Coronavirus disease 19 infection, Respiratory failure azithromycin plus hydroxychloroquine Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institut Mutualiste Montsouris France 2020-03-19 2020-07-31 NCT04452617, REA-03-2020 Phase Not Applicable No longer recruiting 1 4 Months 40 Lyes KNANI, Doctor 2020-07-03
Evaluation of COVID-19 antigen test in COVID-19 suspected cases Coronavirus disease 19 infection COVID-19 antigen test alone Nagasaki University Japan 2020-06-01 UMIN000040386 Phase Not Applicable Not yet recruiting 1 300 Katsunori Yanagihara, Norihito Kaku 2020-07-02
Clinical Trial to Evaluate the Efficacy of Food Supplement Manremyc Against SARS- COV-2 Infection (COVID-19) in Healthcare Workers Coronavirus disease 19 infection Manremyc food supplement alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Reig Jofre Group Spain 2020-07-31 2021-12-31 MANRECOVID19, NCT04452773 Phase Not Applicable Not yet recruiting 3 17 Months 315 Concepcio Violant, Dr, Concepció Violant, Dr., Eli Sánchez, Joan Matllo, Dr., Magda Alemany, Dr., Mª José Argerich, Dr., Pere Joan Cardona, MD, PhD 2020-07-08
Probe-based Confocal Laser Endomicroscopy in Critically Ill COVID-19 Patients Chronic obstructive pulmonary disease, Coronavirus disease 19 infection, Eosinophilia, Eosinophilic granuloma, Hemochromatosis, Lung disease, Lymphangioleiomyomatosis, Pneumonia, Proteinosis, Respiratory failure, Sarcoidosis, Vasculitis, Viral pneumonia Alveoflex miniprobe alone, Cellvizio system (Mauna Kea Technologies) alone, probe-based confocal laser endomicroscopy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Federal Research Center for Specialized Types of Medical Care and Medical Technologies" of FMBA Russian Federation 2020-07-01 2021-09-01 COVID-PCLE, NCT04451889 Phase Not Applicable Recruiting 1 14 Months 15 Olesya Danilevskaya, MD, PhD, Olesya V. Danilevskaya, MD 2020-07-06
Study of Decidual Stromal Cells to Treat COVID-19 Respiratory Failure Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure decidual stromal cells alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) The University Health Network Oslo University Hospital Canada 2020-07-06 2021-01-06 20-5527, DSC-COVID-19, NCT04451291, U-DEPLOY: DSC-COVID-19 Phase 2 Clinical Not yet recruiting 1 6 Months 20 John Granton, M.D., Jonas Mattsson, M.D. 2020-07-08
VPCOVID: VentaProst in Subjects With COVID-19 Requiring Mechanical Ventilation Coronavirus disease 19 infection, Respiratory failure epoprostenol (inhaled, perioperative pulmonary hypertension), Aerogen Pharma alone PGI2 agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Aerogen Pharma Ltd Ohio State University US 2020-07-31 2021-02-01 APC-VPCOV-CLN-001, NCT04452669, VPCOVID Phase 2 Clinical Not yet recruiting 1 6 Months 30 Joe Santiago, BS, RRT, Judy R Doto, RN, BSN, Veronica Franco, MD 2020-07-08
COVID-19-LAT: Study of the Consequences of Infection on Compliance of Modalities of Decisions of Limitations and Stops of Treatments Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Clermont-Ferrand France 2020-06-01 2021-06-30 2020_GUASTELLA_COVID-19-LAT, COVID-19-LAT, NCT04452487 Phase Not Applicable Recruiting 3 13 Months 2500 André BOIBIEUX, Arnaud HOT, Jean-Christophe RICHARD, Jean-Christophe Richard, Laurent ARGAUD, Lise LACLAUTRE, Lise Laclautre, Pascal SEVE, Viginie Guastella, Virginie Guastella 2020-07-03
A study to evaluate the efficacy and safety of Nafamostat Mesilate in treatment of Coronavirus infection Coronavirus disease 19 infection nafamostat mesilate alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Sun Pharmaceutical Industries Ltd India 2020-07-11 CTRI/2020/06/026220, ICR/20/004 Phase 2 Clinical Not yet recruiting 12 40 Dr Maulik Doshi, Dr Shilpi Dhawan, Guruprasad Palekar 2020-07-02
HFNC and NIV for COVID-19 Complicated by Respiratory Failure Coronavirus disease 19 infection, Respiratory failure Airvo 2, Fisher and Paykel alone, Respironics V60 ventilator alone, high flow nasal cannula therapy alone, non-invasive ventilation alone, oronasal mask (Quattro, ResMed) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chinese University of Hong Kong Health and Health Services Research Fund Hong Kong 2020-06-11 2021-06-10 2020.203, NCT04452708 Phase Not Applicable Recruiting 1 12 Months 15 David S Hui, MD, Karen Yiu, BSc, Susanna S Ng, MBChB, Susanna So-Shan Ng 2020-07-02
PROMETEO: Statistical and Epidemiological Study Based on the Use of Convalescent Plasma for the Management of Patients With COVID-19 Coronavirus disease 19 infection, Respiratory failure, Septic shock antibiotic therapy alone, hemodynamic support treatment alone, individualized treatment alone, convalescent plasma plus oxygen Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Autonomous University of Coahuila Consejo Nacional de Ciencia y Tecnología Mexico 2020-07-06 2021-04-01 HUS-001/2020, NCT04452812, PROMETEO Phase 1/Phase 2 Clinical Not yet recruiting 1 8 Months 15 Julio Cesar Martinez Gallegos, MD, MMSc, Julio César Martínez Gallegos, MD, MSc 2020-07-08
A prospective, cohort study to evaluate the connection between NETs and COVID-19 severity and progression Coronavirus disease 19 infection PEEL Therapeutics Inc Cold Spring Harbor Laboratory, Cornell University, University of Utah Health US Phase Not Applicable Status not specified 1 33 2020-07-01
Verification of operating characteristic of COVID-19 antibody test Coronavirus disease 19 infection Nagasaki University Japan 2020-06-16 UMIN000040402 Phase Not Applicable Not yet recruiting 1 100 Katsunori Yanagihara, Norihito Kaku 2020-07-02
Physical Activity Level in Patients With OSAS During Covid-19 Pandemic Coronavirus disease 19 infection, Obstructive sleep apnea Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ahi Evren Education and Research Hospital Turkey 2020-06-25 2020-12-31 GO 20/540, NCT04451993 Phase Not Applicable Recruiting 1 6 Months 60 Adem Celik, MD, Ebru Calik Kutukcu, PhD, Ebru Calik-Kutukcu, PhD, NUREL ERTURK, Naciye Vardar-Yagli, PhD, Nurel Erturk, MsC 2020-07-02
Hesperidin and Diosmin for Treatment of COVID-19 Coronavirus disease 19 infection, Pharyngitis, Respiratory failure, Respiratory tract infection, Rhinitis Daflon alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Tanta University Egypt 2020-07-01 2020-10-30 1111, NCT04452799 Phase 0 Clinical Not yet recruiting 1 3 Months 100 Prof. Dr. Kamal Mohammed Okasha 2020-07-02
NATADEX: NA-83, Atazanavir and Dexamethasone Combination Therapy for the Treatment of COVID-19 Infection Coronavirus disease 19 infection Variable regimens including atazanavir , dexamethasone , traneurocin (Alzheimer's disease), NeuroActiva AMPA receptor modulator, HIV GAG POL polyprotein inhibitor, HIV GAG protein inhibitor, HIV-1 protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) NeuroActiva Inc US 2020-08-15 2021-02-15 NATADEX, NATADEX, NCT04452565 Phase 2/Phase 3 Clinical Recruiting 1 6 Months 525 Brian Tran, MD, Frank Kennedy, PhD, Lloyd Tran, PhD 2020-07-08
Single-Center, Study on Evaluation of use of,'AYURCOV' as add on therapy for Treatment of SARS-CoV-2 Infection in COVID-19 Patients,at Tertiary Care Center Coronavirus disease 19 infection, Lower respiratory tract infection AYURCOV plus Go Ghrut Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bhaktivedanta Hospital and Research Institute India 2020-07-01 CTRI/2020/06/026262 Phase Not Applicable Not yet recruiting 1 120 Dr Nanasaheb Memane, Dr Vijaykumar Gawali 2020-07-07
Resveratrol and copper for the treatment of COVID-19 pnuemonia Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia Nutraceuticals alone, Resveretrol/Copper alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Topiwala National Medical College India 2020-07-10 CTRI/2020/06/026256 Phase Not Applicable Not yet recruiting 1 230 Rosemarie Desouza 2020-07-07
Topical Steroids and Cyclosporin-A for COVID-19 Keratoconjunctivitis Coronavirus disease 19 infection, Keratoconjunctivitis Variable regimens including ciclosporin, Novartis , non-preserved artificial tears , prednisolone Calcineurin inhibitor Mansoura University Ministry of Health in Kuwait Kuwait 2020-06-30 2020-07-31 COVID-19 KERATOCONJUNCTIVITIS, NCT04451239 Phase 2 Clinical Not yet recruiting 1 1 Month 12 Ameera Abdelhameed, MD, Ameera Gamal Abdelhameed, Mona Nasseif, MD 2020-07-02
Correlation of urinary porphyrin and biochemical markers with the severity of symptoms of COVID-19 cases Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) KIIT University India 2020-07-15 CTRI/2020/06/026250 Phase Not Applicable Not yet recruiting 1 100 DR JYOTIRMAYEE BAHINIPATI 2020-07-07
COVLA: Multicentric Registry of Patients With Acute Leukemia Infected by COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) French Innovative Leukemia Organisation Acute Leukemia French Association, Group for Research on Adult Acute Lymphoblastic Leukemia France 2020-08-01 2023-12-01 COVLA, COVLA, NCT04452604 Phase Not Applicable Not yet recruiting 1 40 Months 30 Pierre-Yves DUMAS, Dr, Sarah BERTOLI, Dr 2020-07-02
A compassionate use program of CYT-107 to treat patients with COVID-19 Coronavirus disease 19 infection CYT-107 alone IL-7 receptor agonist Revimmune Inc Phase Not Applicable Status not specified 0 12 2020-07-01
VT-Covid-19: Deep Venous Thrombosis in Non-severe COVID-19 Patients Hospitalized for a Neurovascular Pathology Cerebrovascular disease, Coronavirus disease 19 infection, Deep vein thrombosis, Hemorrhagic stroke, Ischemic stroke, Transient ischemic attack Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopitaux Universitaires de Strasbourg France 2020-06-23 2020-09-23 7908, NCT04452422, VT-Covid-19 Phase Not Applicable Recruiting 1 3 Months 30 Amadou Talibe BALDE, MD, Bernard GENY, MD, PhD, Daniela BINDILA, MD, Nora PIERRE-PAUL Irène, MD, Olivier ROUYER, MD, Saïd CHAYER, PhD, HDR, Valérie WOLFF, MD 2020-07-02
Study Assessing the Efficacy and Safety of Anti-Spike SARS-CoV-2 Monoclonal Antibodies for Prevention of SARS-CoV-2 Infection Asymptomatic in Healthy Adults Who Are Household Contacts to an Individual With a Positive SARS-CoV-2 RT-PCR Assay Coronavirus disease 19 infection REGN-CoV2 alone COVID19 Spike glycoprotein inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Allergy and Infectious Diseases, National Institutes of Health, Regeneron Pharmaceuticals Inc US 2020-06-30 2021-04-11 NCT04452318, R10933-10987-COV-2069 Phase 3 Clinical Recruiting 1 9 Months 2000 Clinical Trial Management, Clinical Trials Administrator, Dr. Suraj Saggar 2020-07-09
Effect of hydroxychloroquine treatment on the general immunocompetence Coronavirus disease 19 infection Hydroxychloroquine sulphate alone Healthy volunteers accepted, Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Centre for Human Drug Research Netherlands 2020-06-01 2020-09-09 CHDR2014, NL73816.056.20, NL8726 Phase 2 Clinical Recruiting 1 3 Months 40 M. Moerland 2020-07-07
Use of hUC-MSC Product (BX-U001) for the Treatment of COVID-19 With ARDS Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia BX-U001 alone, best supportive care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Baylx Inc 2020-09-01 2021-12-31 BXU001-COVID19, NCT04452097 Phase 1 Clinical Not yet recruiting 0 16 Months 9 Vincent Liao, MD. Ph.D. 2020-07-02
PRO-COVID-19: Primary care Research on Outcomes of COVID-19 Coronavirus disease 19 infection, Respiratory tract infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universiteit Utrecht The Netherlands Organisation for Health Research and Development Netherlands 2020-08-01 2021-08-01 NL8729, PRO-COVID-19, volgt Phase Not Applicable Not yet recruiting 1 12 Months 274 Tamara Platteel 2020-07-07
COVID-19 and Rare Skin Diseases European Observational Study During an Epidemic Coronavirus disease 19 infection, Dermatological disease Imagine Institute France 2020-06-30 2021-06-30 COVID19-RARESKIN, NCT04451902 Phase Not Applicable Not yet recruiting 1 12 Months 80 Christine BODEMER, Rébecca GENE 2020-07-09
Acceptability of Telehealth Triage Using Robotic Systems in COVID-19 Coronavirus disease 19 infection Doctor Spot, Boston Dynamics alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Brigham & Women's Hospital US 2020-03-10 2020-07-31 2020P000957, NCT04452695 Phase Not Applicable Recruiting 1 4 Months 50 Carlo G Traverso, MD PhD, Peter R Chai, Peter R Chai, MD MMS 2020-07-02
CardioPostCovid: Cardiovascular Consequences After COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux De Marseille France 2020-06-23 2021-11-30 2020-36, CardioPostCovid, NCT04452630 Phase Not Applicable Recruiting 1 17 Months 200 Franck THUNY, MD 2020-07-02
ETHIC: An open-label, randomized controlled trial of community-based Early Thromboprophylaxis in COVID-19 Coronavirus disease 19 infection, Thrombosis enoxaparin sodium alone, low molecular weight Heparin alone Low molecular weight heparin Thrombosis Research Institute Sanofi SA 2020-07-31 ETHIC Phase Not Applicable Planned 0 1400 2020-07-01
NutriCoviDom: Nutritional Follow-up After Hospital Discharge for Coronavirus Disease-19 Coronavirus disease 19 infection, Dysgeusia, Dysomia nutritional evaluation alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Hospital, Nancy, France France 2020-04-01 2020-11-30 2020PI097, NCT04451694, NutriCoviDom Phase Not Applicable Recruiting 1 8 Months 800 Didier Quilliot, Didier Quilliot, Md PhD, marine Gerard, resident 2020-07-02
PhysiCOVID: Changes in Physical and Sports Activity, Anxiety and Sleep Patterns Following the Containment Period Imposed by the COVID-19 Pandemic in Patients With Chronic Medical Conditions and in Healthy Athletes Anxiety disorder, Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire de Toulouse France 2020-06-30 2020-08-31 NCT04451317, PhysiCOVID, RC31/20/0203 Phase Not Applicable Not yet recruiting 1 2 Months 600 Fabien PILLARD, Fabien pillard 2020-07-02
Study of the Efficacy and Safety of a Single Administration of Olokizumab versus Placebo in Addition to Standard Treatment in Patients With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection (COVID-19) Coronavirus disease 19 infection, Viral pneumonia olokizumab alone, standard therapy alone IL-6 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) R-Pharm Covance Inc, Cromos Pharma, LLC US 2020-06-30 2021-01-29 CL04041080, NCT04452474 Phase 2/Phase 3 Clinical Not yet recruiting 6 7 Months 376 Daniel Skiest, David Parenti, Jennifer Killion, Judith Pride, Karan Fachet, Mikhail Samsonov, Robert Buynak, Viveka Boddapalli 2020-07-02
PREDCOVID: Early Use of Corticosteroids in Hospitalized Patients With Moderate COVID-19 Pneumonia Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia prednisone alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Chile Chile 2020-06-25 2020-09-30 100, NCT04451174, PREDCOVID Phase 3 Clinical Not yet recruiting 1 3 Months 184 Mauricio Salinas 2020-07-03
A Phase II, Randomized Clinical Trial of CYTO-201 in COVID-19 Patients Coronavirus disease 19 infection naltrexone (low dose oral formulation, cancer/immune diseases/inflammatory bowel disease/ulcerative colitis/COVID-19), Cytocom alone, standard care alone Opioid receptor antagonist Cytocom Inc US Phase 2 Clinical Planned 1 2020-07-10
The Role of Anticoagulant and Thrombolitic in Treatment of COVID Patients Coronavirus disease 19 infection tissue plasminogen activator alone, unfractional heparin alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Tabriz University of Medical Sciences Iran 2020-06-17 IR.TBZMED.REC.1399.127, IRCT20200515047456N1 Phase 3 Clinical Recruiting 1 15 Farid Rashidi, Farid Rashidi, MD 2020-07-01
Insolcov-19: Analytical study of the profile of pro-inflammatory and pro-resolution factors in non-obese males with pulmonary symptomatology resulting from SARS COVID-19 verified with PCR blood analysis Coronavirus disease 19 infection, Inflammatory disease, Viral pneumonia blood testing alone Healthy volunteers accepted, Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Insud Pharma Chile 2020-06-29 19 Junio 2020, DRKS00022337, Insolcov-19 Phase 1 Clinical Not yet recruiting 1 20 Pedro-Antonio Regidor, Rafael Silva Orellana 2020-07-01
A Phase III Trial of Leronlimab for the Treatment of Covid-19 in Severe and Critically Ill Patients Coronavirus disease 19 infection leronlimab alone CCR5 chemokine antagonist CytoDyn Inc National Institutes of Health and High Specialty Hospitals Mexico Phase 3 Clinical Planned 1 25 2020-06-30
Trauma Healing Project Based on Chinese Mind-Body Wisdom in the novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection Mindfulness practice alone, One to one consultation alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The institute of psychology, Chinese Academy of Sciences China 2020-03-11 2021-03-31 COVID19_IMPACT, ChiCTR2000034164, EOCX331008 Phase Not Applicable Not yet recruiting 1 12 Months 340 Di Long, Yanan Niu 2020-07-01
AK-TIR-COVID-19: Antibody Assesement for COVID-19 Prevalence 2 months After Outbreak in the Hotspot Region of Tirschenreuth/Bavaria Coronavirus disease 19 infection blood sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kliniken Nordoberpfalz AG Germany 2020-06-29 2020-1112, AK-TIR-COVID-19, DRKS00021813 Phase 4 Clinical Not yet recruiting 1 2500 Thomas Finkenzeller 2020-07-01
Effect of mandala staining on anxiety in patients with COVID-19 Anxiety disorder, Coronavirus disease 19 infection mandala staining alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Arak University of Medical Sciences and Health Services Iran 2020-07-19 IR.ARAKMU.REC.1399.089, IRCT20180519039711N6 Phase Not Applicable Not yet recruiting 1 60 Dr. alireza kamali, Fatemeh Khademi, Mohamad Golitaleb 2020-07-01
Validation of Rapid Test kit for Antibody (IgG, IgM) detection against COVID19 Coronavirus disease 19 infection Rapid Test Kit alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Maulana Azad Medical College India 2020-07-03 CTRI/2020/06/026120 Phase Not Applicable Not yet recruiting 1 50 Dr Pallavi, Dr Sonal Saxena, Dr Urmila Jhamb, Dr Vikas Manchanda 2020-07-01
A clinical trial of SFA-005 for the potential treatment and prevention of acute respiratory distress syndrome (ARDS) in patients with SARS-CoV-2 virus infection (COVID-19) Coronavirus disease 19 infection, Respiratory distress syndrome SFA-005 alone Free fatty acid receptor 2 agonist, Free fatty acid receptor 3 agonist SFA Therapeutics Phase Not Applicable Planned 0 2020-06-30
Delivery of Protocolized Emergency Surgical Care During COVID-19 Pandemic Coronavirus disease 19 infection, Respiratory disease, Surgical procedure emergency surgery alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Khoo Teck Puat Hospital Singapore 2020-04-01 2020-05-31 2020/00660, NCT04450277 Phase Not Applicable Completed 1 2 Months 15 2020-07-08
Povidone-Iodine Rinses in the Management of COVID-19 Coronavirus disease 19 infection Betadine (povidone-iodine) alone, NeilMed sinus rinse bottle alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) St. Paul's Hospital Canada 2020-07-01 2020-12-01 BETADINE COVID-19, NCT04449965 Phase 0 Clinical Not yet recruiting 1 5 Months 81 Amin Javer, Laura Samson 2020-07-02
A clinical trial of SARS-CoV-2 DNA vaccine (intrademal, COVID-19), Immunomic Therapeutics/EpiVax for the potential intradermal prevention of SARS-CoV-2 infection (COVID-19) Coronavirus disease 19 infection SARS-CoV-2 DNA vaccine (intrademal, COVID-19), Immunomic Therapeutics/EpiVax alone Immunomic Therapeutics Inc, Replicate Bioscience Inc Phase Not Applicable Planned 0 2020-06-30
Collection of clinical data in patients with inflammatory rheumatic disease during the pandemic with the SARS-CoV-2 virus - COVID-19 Connective tissue disease, Coronavirus disease 19 infection, Psoriatic arthritis, Rheumatoid arthritis, Spondylarthritis Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rheumazentrum Ruhrgebiet Herne Germany 2020-04-19 20-6901, DRKS00021780 Phase 4 Clinical Recruiting 1 1521 Jurgen Braun 2020-07-03
Vitamin D Supplementation in Patients With COVID-19 Coronavirus disease 19 infection conventional care alone, vitamin D3 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Sao Paulo Brazil 2020-06-01 2020-11-30 30959620.4.0000.0068, NCT04449718 Phase Not Applicable Recruiting 1 6 Months 200 Bruno Gualano, PhD, Rosa Pereira, PhD, MD 2020-07-01
CHICANE: Preoperative Shielding and N/T RT-PCR Swabbing for Elective Cancer Surgery Coronavirus disease 19 infection RT-PCR alone, nose and throat swabbing alone, telephone consult alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Liverpool University Hospitals NHS Foundation Trust UK 2020-06-25 2020-09-25 CHICANE, NCT04449783, SP0355 Phase Not Applicable Not yet recruiting 1 3 Months 150 Peter Gaskell, MBChB, Robert Jones, MBChB 2020-07-01
TARGet Kids! COVID-19 Study of Children and Families Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs) Hospital for Sick Children St Michaels Hospital Canada 2020-04-09 2022-12-31 1000069701, NCT04449978 Phase Not Applicable Recruiting 2 32 Months 1082 Catherine S Birken, MD, Christine Kowal, MSc, Dalah C Mason, MPH, Dalah Mason, MPH, Jonathon Maguire, MD 2020-07-01
A phase II clinical trial of tridecasodium pixatimod for the treatment of COVID-19 Coronavirus disease 19 infection tridecasodium pixatimod alone Coronavirus spike glycoprotein inhibitor, FGF-1 ligand inhibitor, FGF-2 ligand inhibitor, Heparanase inhibitor, VEGF ligand inhibitor Zucero Therapeutics Ltd Sweden, Australia, US, UK Phase 2 Clinical Planned 4 2020-06-30
Safety, Tolerability and Immunogenicinity of a Coronavirus-Like Particle COVID-19 Vaccine in Adults Aged 18 to 55 Years Coronavirus disease 19 infection SARS-CoV-2 vaccine (VLP, COVID-19), Medicago alone, adjuvant A adjuvanted coronavirus-like particle COVID-19 vaccine alone, adjuvant B adjuvanted coronavirus-like particle COVID-19 vaccine alone, coronavirus-like particle COVID-19 vaccine unadjuvanted alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Medicago Inc GlaxoSmithKline plc 2020-07-10 2021-04-30 CP-PRO-COVLP-019, NCT04450004 Phase 1 Clinical Not yet recruiting 0 9 Months 180 Brian J Ward, MD 2020-07-10
COVIDiet-Int: Changes in Dietary Behaviors During the COVID-19 Outbreak Confinement in the Adult Population Coronavirus disease 19 infection MEditerranean Diet Adherence Screener (MEDAS) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Granada Bezmialem Vakif University, Centro Hospitalar e Universitário de Coimbra, E.P.E., Institute for Public Health (EU), Institute of Technology Sligo, Jozef Stefan Institute, Lithuanian University of Health Sciences, Ss. Cyril and Methodius University of Skopje, University of Athens, University of Belgrade, University of Kuwait, University of Sarajevo, University of Southern Denmark, University of Zagreb, Uniwersytet Przyrodniczy w Poznaniu Spain 2020-03-20 2021-06-30 1526/CEIH/2020, COVIDiet-Int, NCT04449731 Phase Not Applicable Recruiting 1 15 Months 30000 Belén García-Villanova Ruíz, PhD, Celia Rodríguez Pérez, Celia Rodríguez Pérez, PhD, Celia Rodríguez-Pérez, PhD, Eduardo Jesús Guerra-Hernández, PhD, Esther Molina-Montes, PhD, María Dolores Ruíz López, PhD, María Dolores Ruíz-López, PhD, Reyes Artacho Martín-Lagos, PhD, Vito Verardo, PhD 2020-07-01
Clinical Features of Severe Patients With COVID-19 Coronavirus disease 19 infection, Viral pneumonia CT scan alone, arterial ultrasound alone, echocardiography alone, electrocardiography alone, venous ultrasound alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Federal Research Center for Specialized Types of Medical Care and Medical Technologies" of FMBA Russian Federation 2020-04-06 2020-08-31 COVID-ICU, NCT04450017 Phase Not Applicable Recruiting 1 4 Months 150 Irina A Mandel, PhD, Tatiana V Klypa, Dr.Med.Sc. 2020-07-01
Safety and Efficacy of C21 in Subjects With COVID-19 Coronavirus disease 19 infection, Respiratory tract infection VP-01 alone Angiotensin II AT-2 receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) QED Clinical Services India Pvt Ltd, Vicore Pharma AB Orphan Reach UK, Russian Federation, Ukraine, India 2020-06-30 2021-09-30 2020-001502-38, CTRI/2020/06/026192, NCT04452435, VP-C21-006 Phase 2 Clinical Recruiting 15 15 Months 100 Joanna Porter, MD, Kartikeya Parmar, MD, Mimi Flensburg, DVM PhD, Reema Kashiva, MD 2020-07-01
To study the safety and efficacy of Vitamin D3, Vitamin K2-7 and magnesium , in prevention of COVID 19 infection in health care professional (HCP) Coronavirus disease 19 infection Variable regimens including Magnesium Glycinate , Vitamin K2 , vitamin D3 Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Suraksha Pharma Private Limited India 2020-08-01 CTRI/2020/06/026191, MUR/01/2020 Phase 2 Clinical Not yet recruiting 1 500 AVN Sridhar, Dr Sudarsi B 2020-07-01
A Trial of Shirashadi Kasai in patients with Covid-19 Coronavirus disease 19 infection Shirashadi Kasai alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institute of Medical Sciences, Banaras Hindu University Ministry of Ayush India 2020-07-14 CTRI/2020/06/026190 Phase 2 Clinical Not yet recruiting 1 160 Abhishek Pandey, Jaya Chakravarty 2020-07-02
Clinical trial of herbal supplement as an immunomodulator in adult Covid 19 positive patients Coronavirus disease 19 infection standard treatment alone, ACT 13 plus ACT12 Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) GPLIFE HEALTHCARE PRIVATE LIMITED India 2020-07-05 CTRI/2020/06/026187, PROTOCOL NO- MHC/CT/20-21/002 Phase Not Applicable Status not specified 1 60 Pawan Kumar Singh, Shridhar Pandya, Tushar V Patil 2020-07-09
Homoeopathy as an add-on in treatment of COVID-19 Coronavirus disease 19 infection homoeopathic medicine therapy alone, standard treatmet alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Council for Research in Homoeopathy India 2020-07-08 CTRI/2020/06/026195 Phase 2/Phase 3 Clinical Not yet recruiting 2 300 Dr Anil Khurana, Dr Anupriya, Dr Debadatta Nayak, Dr Juhi Gupta 2020-07-05
A study of drug Lithium on patients of Covid 19 disease Coronavirus disease 19 infection Variable regimens including azithromycin , hydyoxychloroquine , lithium carbonate Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) LNJP Hospital, Maulana Azad Medical College India 2020-07-30 CTRI/2020/06/026193 Phase 2 Clinical Recruiting 1 100 Dr Sumit Sural 2020-07-01
AMMURAVID: A study with immunotherapy for Moderate COVID-19 Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia Urbason alone, baricitinib alone, canakinumab alone, sarilumab alone, siltuximab alone, tocilizumab (subcutaneous), Roche/Chugai alone Heat shock protein inhibitor, IL-6 receptor antagonist, Immunoglobulin G1 agonist, Interleukin-1 beta ligand inhibitor, Jak1 tyrosine kinase inhibitor, Jak2 tyrosine kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) SOCIETA' ITALIANA MALATTIE INFETTIVE E TROPICALI The Italian Medicines Agency Italy 2020-04-27 2020-001854-23, AMMURAVID, AMMURAVID Phase 2/Phase 3 Clinical Recruiting 1 1400 Malattie Infettive 2020-07-01
Conscious posture therapy and covid 19 hypoxemia Coronavirus disease 19 infection, Hypoxia Conscious posture therapy alone, non invasive oxygen administrative devices alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Postgraduate Institute of Medical Education and Research India 2020-07-10 CTRI/2020/06/026198 Phase Not Applicable Not yet recruiting 1 60 Kulbhushan saini 2020-07-02
Validation of Classical Ayurvedic formulations in treatment of COVID-19 Coronavirus disease 19 infection Sudarshan Ghanvati plus Vyaghradi Kwath Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ministry of Ayush India 2020-07-06 CTRI/2020/06/026197 Phase 3 Clinical Not yet recruiting 1 60 Dr Amanpreet Kaur 2020-07-07
The effect of bromelain and montelukast in COVID-19 patients Coronavirus disease 19 infection, Cough, Dyspnea, Fever Anaheal capsule (Parmon Amin Health Company) alone, Anaheal capsule (Parmon Amin Health Company) plus montelukast sodium Leukotriene D4 antagonist Shaheed Beheshti Medical University Iran 2020-04-20 IR.SBMU.NRITLD.REC.1399.060, IRCT20150725023332N3 Phase 3 Clinical Recruiting 1 60 Afshin Zarghi, Alireza Jahangirifard, Behrooz Farzanegan, Seyed Bashir Mirtajani 2020-06-30
Drug Trial to Evaluate Efficacy and Safety of an Ayurvedic Formulation as Adjunct Treatment to Standard of Care for the management of Mild to Moderate COVID-19 Patients Coronavirus disease 19 infection, Viral pneumonia AYUSH 64 alone, Samshamani Vati Plus alone, Standard of Care alone, Yashtimadhu alone, Guduch plus Pippali Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Council of Scientific and Industrial Research (India), Ministry of Ayush India 2020-07-20 COVID 19/AYUSH-ICMR 2020/Adjunct Protocol-AF-II, CTRI/2020/06/026161 Phase Not Applicable Not yet recruiting 1 140 Dr Dilip Mondhe, Dr Sushila Kataria, Mr Chandu Devanpally, Pranjal Ausekar 2020-07-01
COVID-19 in dialysis patients Coronavirus disease 19 infection, End stage renal disease Hemodialysis alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Seth GS Medical College India 2020-06-26 CTRI/2020/06/026152 Phase Not Applicable Not yet recruiting 1 120 Dr Sayali Thakare, Dr Tukaram Jamale 2020-07-07
Psychological Assessment of adult COVID-19 patients Coronavirus disease 19 infection Psychological Assessment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) KIMS Hospital India 2020-07-06 CTRI/2020/06/026188 Phase Not Applicable Not yet recruiting 1 240 Jayaprakash Russell Ravan 2020-07-01
Steroids and unfractionated heparin in critically-ill patients with pneumonia from COVID-19 infection. A multicenter, interventional, randomized, three-arms study design Coronavirus disease 19 infection, Viral pneumonia Veracer plus methylprednisolone (Pfizer) Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Modena Italy 2020-05-14 2020-001921-30, STAUNCH-19 Phase 3 Clinical Recruiting 1 200 Clinical Trials Quality Team 2020-06-30
MICO: Role of Microparticles in Covid-19 Infection Coronary artery disease, Coronavirus disease 19 infection prothrombinase assay alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopitaux Universitaires de Strasbourg 2020-06-30 2021-11-30 7829, MICO, NCT04448743 Phase Not Applicable Not yet recruiting 0 17 Months 175 2020-07-01
Covid: To Compare the safety and efficacy of Vitamin D, with Magnesium in mild to moderate Covid 19 patients Coronavirus disease 19 infection Magnesium plus Vitamin D3 Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Suraksha Pharma Private Limited India 2020-08-01 CTRI/2020/06/026189, Covid Phase 2 Clinical Not yet recruiting 1 210 AVN Sridhar, Neethi Chandra 2020-06-30
Emergence of the COVID-19 Epidemic in the City of Nice Coronavirus disease 19 infection Healthy volunteers accepted Centre Hospitalier Universitaire De Nice France 2020-02-28 2020-04-04 20DSPCOVID01, NCT04449094 Phase Not Applicable Completed 1 1 Month 200 2020-06-30
Characterization of Reverse Triggering and Other Asynchronies in COVID-19 Patients Under Invasive Mechanical Ventilation Coronavirus disease 19 infection, Respiratory distress syndrome asynchronies detection alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Corporacion Parc Tauli Spain 2020-03-09 2020-06-30 NCT04448782, RT COVID-19 Phase Not Applicable Recruiting 1 3 Months 30 Candelaria De Haro, MD, Candelaria de Haro 2020-06-30
Knowledge, Attitude and Practice of Dental Students About COVID-19 Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs) Melaka Manipal Medical College Malaysia 2020-04-25 2020-06-20 MELAKAMMC, NCT04449081 Phase Not Applicable Completed 1 1 Month 215 Rajesh Hosadurga, Ph.D 2020-06-30
Hydro-STOP-COVID19: Hydroxychloroquine sulfate early administration in symptomatic out of hospital COVID-19 positive patients Coronavirus disease 19 infection Plaquenil alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) ASUR (Azienda Sanitaria Unica Regionale) Marche Italy 2020-04-09 2020-001558-23, COFID19-AIFA17/2020, Hydro-STOP-COVID19 Phase 3 Clinical Recruiting 1 216 UOC Cardiologia ASUR AV5 2020-06-30
A clinical trial of SK1-I for the potential treatment of COVID-19 Coronavirus disease 19 infection SK1-I alone Sphingosine kinase 1 inhibitor Enzo Biochem Inc Phase Not Applicable Planned 0 2020-06-29
PAWS-COVID-19: Pediatric Airway Complications COVID-19 Registry Coronavirus disease 19 infection, Hypoxia, Respiratory disease airway management alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Boston Children’s Hospital Ann & Robert H Lurie Children's Hospital of Chicago, Children's Hospital Colorado, Childrens Hospital of Philadelphia, Perth Children's Hospital, Royal Hospital for Sick Children, The Gaslini Institute US 2020-04-01 2025-12-31 IRB-P00035427, NCT04449042, PAWS-COVID-19 Phase Not Applicable Recruiting 1 69 Months 15000 John E Fiadjoe, MD, Mary Lyn Stein, Mary Lyn Stein, MD, Pete Kovatsis, MD 2020-06-30
Mental Health of Health Care Workers during COVID-19 pandemics Coronavirus disease 19 infection, Psychotic disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kalinga Institute of Medical Sciences India 2020-07-06 CTRI/2020/06/026184, r2cd58 Phase Not Applicable Not yet recruiting 1 100 RAMA CHANDRA DAS 2020-06-30
COVAL-NANCY: Epidemiological Study of Seroprevalence Against the SARS-CoV-2 Virus (COVID-19) Coronavirus disease 19 infection ELISA alone Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Hospital, Nancy, France Métropole du Grand Nancy, Université De Lorraine France 2020-06-26 2020-08-31 2020PI128, COVAL-NANCY, NCT04448769 Phase Not Applicable Recruiting 2 2 Months 2000 Evelyne SCHVOERER, Evelyne Schvoerer, Karine LEGRAND, Marjorie STARCK 2020-07-10
CiaoCorona: Longitudinal Study of Seroprevalence of SARS-CoV-2 Antibodies and Development of Immunity in School Children Coronavirus disease 19 infection COVID-19 antibody testing alone Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) University of Zurich Foundation Swiss School of Public Health Switzerland 2020-06-16 2021-03-31 2020-01336, CiaoCorona, NCT04448717 Phase Not Applicable Recruiting 1 9 Months 2500 Susi Kriemler, Dr.med., Susi Kriemler, Prof. 2020-06-30
Herbal Steaminhaler clinical trial on COVID patients Coronavirus disease 19 infection AZADVIR alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) HAOMA WELLNESS CENTER India 2020-07-04 CT/AZADVIR /2020, CTRI/2020/06/026181 Phase 3 Clinical Not yet recruiting 1 40 Kavya Kannoth Shaji, SHAJI KANNOTH 2020-06-30
INTERCOP: Clinical Study for the Treatment With Interferon-beta-1a (IFNbeta-1a) of COVID-19 Patients Coronavirus disease 19 infection, Viral pneumonia interferon beta-1a alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) IRCCS San Raffaele Italy 2020-07-31 2021-04-30 INTERCOP, INTERCOP, NCT04449380 Phase 2 Clinical Not yet recruiting 1 9 Months 126 Emanuele Bosi, Professor, Patrizia Rovere Querini, Professor 2020-07-01
ANEMONE: M-5049 Study in Participants With Coronavirus Disease 2019 (COVID-19) Pneumonia Coronavirus disease 19 infection, Viral pneumonia M-5049 alone, standard of care (antiviral treatment) alone TLR-7 antagonist, TLR-8 antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Serono Research Institute Inc Merck KGaA Brazil, US 2020-06-27 2020-11-13 2020-002248-22, ANEMONE, MS200569_0026, NCT04448756 Phase 2 Clinical Not yet recruiting 4 4 Months 150 Communication Center, Medical Responsible, US Medical Information 2020-07-01
Understanding the Mental Health of Migrant Workers During the COVID-19 Outbreak Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Yale-NUS College Singapore 2020-06-22 2020-12-31 CCF@EXPO/R001/2020, NCT04448704 Phase Not Applicable Recruiting 1 6 Months 1000 Edina Tan, Jean Liu, PhD 2020-07-01
The association between the neutralizing activity and the amount of antibody in early stages of SARS-CoV-2 infection: A multicenter, observational study Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Yokohama City University Japan Agency for Medical Research and Development Japan 2020-07-10 UMIN000040931 Phase Not Applicable Not yet recruiting 1 150 Takahiro Mihara, Takeharu Yamanaka 2020-07-09
The prophylactic effect of oral hydroxychloroquine in close contacts of COVID-19 patients Coronavirus disease 19 infection hydroxychloroquine alone Boushehr University of Medical Sciences Iran 2020-06-21 IR.BPUMS.REC.1399.017, IRCT20200513047426N1 Phase 3 Clinical Recruiting 1 500 Dr.Ramin Rezaee, Ramin Rezaee, Vice chancellery for research and technology 2020-07-01
Effect of medical beer on COVID-19 Coronavirus disease 19 infection, Fever Ministry of Health based COVID-19 treatment alone, medical bear intake alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Isfahan University of medical Sciences Iran 2020-03-29 IR.MUI.MED.REC.1399.078, IRCT20200428047229N1 Phase 3 Clinical Recruiting 1 60 Akram Izadikhah, Hanieh Tahermohammadi, Mojgan Tansaz 2020-07-01
A Study to Evaluate the Safety, Reactogenicity and Immunogenicity of Vaccine CVnCoV in Healthy Adults Coronavirus disease 19 infection SARS-CoV-2 mRNA vaccine (COVID-19), CureVac alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) CureVac AG Coalition for Epidemic Preparedness Innovations Germany, Belgium 2020-06-18 2021-08-31 2020-001286-36, CV-NCOV-001, NCT04449276 Phase 1 Clinical Recruiting 4 14 Months 168 Clinical Trial Information 2020-07-07
Evaluation of the effect of ivermectin in the treatment of coronavirus infection Coronavirus disease 19 infection ivermectin (Tadbir Kalaye Jam Company) alone, national protocol based standard drug treatment alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mazandaran University of Medical Sciences Iran 2020-05-21 IR.MAZUMS.REC.1399.057, IRCT20111224008507N3 Phase 3 Clinical Recruiting 1 60 Dr Majid Saeidi, Dr. Mohammad Sadegh Rezai, Fatemeh Hosseinzadeh, Modammad Sadegh Rezai, MD, Mohammadsadegh Rezai 2020-07-01
Serological screening and metabolic analysis for evaluation of the immune response to SARS-CoV2 (COVID-19) Coronavirus disease 19 infection Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Klinikum der Albert-Ludwigs Universitaet Freiburg Germany 2020-06-01 305/20, DRKS00022292 Phase 0 Clinical Recruiting 1 250 Cornelius Waller 2020-07-01
A phase I/II clinical trial to evaluate the safety, tolerability, immunogenicity and efficacy of Covigenix for treatment of COVID-19 Coronavirus disease 19 infection SARS-CoV-2 DNA vaccine (COVID-19), Entos/ Epivax alone COVID19 Spike glycoprotein modulator Canadian Center for Vaccinology, Entos Pharmaceuticals Inc Canada Phase 1/Phase 2 Clinical Planned 1 2020-06-29
C-19 ST: COVID-19 Symptom Tracker Coronavirus disease 19 infection app-based questionnaire alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Klinikum der Albert-Ludwigs Universitaet Freiburg Liechtenstein, Austria, New Zealand, UK, Germany, Spain, US, Uruguay, Switzerland, Australia, France 2020-04-13 337/20, C-19 ST, DRKS00021305 Phase Not Applicable Recruiting 11 100000 Martin Zens 2020-07-02
Zinc With Chloroquine/Hydroxychloroquine in Treatment of COVID-19 Coronavirus disease 19 infection Alexoquine (chloroquine) alone, Variable regimens including Alexoquine (chloroquine) , hydroxychloroquine , zinc Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tanta University Egypt 2020-06-23 2020-08-01 NCT04447534, TANTA ZINC CHLOROQUINE Phase 3 Clinical Recruiting 1 1 Month 200 Sherief Abd-Elsalam, Sherief Abd-Elsalam, Ass. Prof., Sherief Abd-Elsalam, ass. prof., Sherief abd-elsalan, ass. prof. 2020-06-29
Expanded clinical use of CIGB-258 in the treatment of serious or critically ill patients by COVID-19 (COVID-19) Coronavirus disease 19 infection CIGB-258 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Center for Genetic Engineering and Biotechnology Ministerio de Salud Publica Cuba 2020-04-27 2020-08-30 IG/CIGB-258/UCE, RPCEC00000321 Phase 2 Clinical Recruiting 2 4 Months 35 Maria Dominguez Orta, Rafael Venegas Rodriguez, Verena Muzio Gonzalez 2020-06-29
A Phase I clinical trial to evaluate the safety, tolerance and preliminary immunogenicity of different doses of a SARS-CoV-2 mRNA vaccine in population aged 18 to 59 years and 60 years and above Coronavirus disease 19 infection, Viral pneumonia mRNA vaccine (Lipid Nano Particle, COVID-19), Walvax Biotechnology/Suzhou Abogen Biosciences alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Guangxi Center For Disease Control & Prevention, Suzhou Abogen Biosciences, Walvax Biotechnology Co Ltd China 2020-06-25 2021-12-31 ChiCTR2000034112 Phase 1 Clinical Not yet recruiting 2 18 Months 168 Lin Yuan, Shuyuan Yang 2020-06-30
Novel coronavirus pneumonia (COVID-19) loaded autologous dendritic cell trial Coronavirus disease 19 infection, Viral pneumonia autologous dendritic cell vaccine (injection, COVID-19), Beijing TIL Therapeutics alone COVID19 Spike glycoprotein modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Beijing TIL Therapeutics Co Ltd, Liaocheng People's Hospital China 2020-04-16 2022-04-15 ChiCTR2000034076 Phase 0 Clinical Recruiting 1 24 Months 25 Shengjun Ma, Xiang Xiaoyu 2020-06-29
Evaluating the effect of Phyllanthus Emblica, Rosa Damascene, Marshmallow and Honey on COVID 19 Coronavirus disease 19 infection Variable regimens including Althaea officinalis , Honey , Phyllanthus emblica , Rosa damascene Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ahvaz University of Medical Sciences Iran 2020-06-27 IR.AJUMS.REC.1399.208, IRCT20200404046937N3 Phase 3 Clinical Recruiting 4 60 Mehran Varnaseri Ghandali, Mohammad Badavi 2020-07-01
CONTROL-COVID: Control of COVID-19 Outbreaks in Long Term Care Coronavirus disease 19 infection, Viral respiratory tract infection favipiravir alone RNA polymerase inhibitor Aged Adults (65-79 yrs), Elderly Adults (80 and over) Appili Therapeutics Inc Applied Health Research Centre (AHRC), Toronto, Mount Sinai Hospital, Sunnybrook Health Sciences Centre, The University Health Network, Unity Health Toronto Canada 2020-06-30 2021-03-31 CONTROL-COVID, CONTROL-COVID-FAVIPIRAVIR-1, NCT04448119 Phase 2 Clinical Not yet recruiting 1 9 Months 760 Allison J McGeer, MD, Yoav Golan, MD 2020-07-04
Covid-19 Lockdown and Deviant Sexual Fantasies Anxiety disorder, Coronavirus disease 19 infection, Sexual deviation Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Montpellier France 2020-06-18 2020-10-30 NCT04448405, RECHMPL20_0341 Phase Not Applicable Recruiting 1 4 Months 100 Celine BAIS, Celine BAIS, PhD 2020-07-08
LACCPT: Lagos Covid-19 Convalescent Plasma Trial Coronavirus disease 19 infection Convalescent Plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Lagos State Ministry of Health Nigeria 2020-08-01 2020-09-30 LACCPT, PACTR202006760881890 Phase 2 Clinical Not yet recruiting 3 2 Months 100 Akin Abayomi, Bodunrin Osikomaiya, Hussein AbdurRazzaq 2020-06-29
Resveratrol in COVID19 Coronavirus disease 19 infection resveratrol alone, routine drug therapy alone Ahvaz University of Medical Sciences Iran 2020-06-14 IR.AJUMS.REC.1399.175, IRCT20200112046089N1 Phase 3 Clinical Recruiting 1 50 Arash Alghasi, Mohamad Badavi, Mohammad Reza Mahmoudian-Sani 2020-06-29
Safety, Tolerability and Immunogenicity of INO-4800 Followed by Electroporation in Healthy Volunteers for COVID19 Coronavirus disease 19 infection CELLECTRA 2000 alone, INO-4800 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Inovio Pharmaceuticals Inc, International Vaccine Institute, Seoul National University Coalition for Epidemic Preparedness Innovations, The Korea National Institute of Health South Korea 2020-06-22 2022-02-22 IVI COVID19-001, NCT04447781 Phase 1/Phase 2 Clinical Not yet recruiting 1 20 Months 160 Anh Wartel, MD, Chulwoo Rhee, MD,MSc, Eu Suk Kim, MD, Myoung-don Oh, MD 2020-06-29
ANTICOV: An open-label, multicentre, randomised, adaptive platform trial of the safety and efficacy of several therapies, including antiviral therapies, versus control in mild/moderate cases of COVID-19 Coronavirus disease 19 infection, Viral pneumonia Hydroxychloroquine alone, lopinavir + ritonavir alone HIV protease inhibitor Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Barcelona Institute for Global Health, Bernhard-Nocht-Institute for Tropical Medicine, Centre Pasteur du Cameroun, Drugs for Neglected Diseases Initiative, Epicentre (MSF), INSERM, Ifakara Health Institute, Institute of Tropical Medicine, Belgium, Swiss Centre for Scientific Research Cameroon, Kenya, Ethiopia, Burkina Faso, Congo, The Democratic Republic of the, Uganda, Tanzania, Ivory Coast, Ghana, Equatorial Guinea, Mozambique, Sudan, Guinea 2020-07-20 2021-12-31 ANTICOV, PACTR202006537901307 Phase 2 Clinical Not yet recruiting 18 17 Months 3000 James Arkinstall, Nathalie Strub Wourgaft 2020-06-30
Nutritional Habits, and Coronavirus Disease 2019 (COVID-19) Outcome Coronavirus disease 19 infection Variable regimens including acetylcysteine , hydroxychloroquine , lacorferrin , vitamin C , zinc Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cairo University Egypt 2020-06-01 2020-09-01 1003, NCT04447144 Phase Not Applicable Recruiting 1 3 Months 200 Ahmed M Abdul Ghani, MD, Mona A Hegazy, MD, Mona Hegazy, Mona M Abd-Elmonem Hegazy, MD 2020-07-01
COVID-19 in inpatient care facilities (nursing homes) in Thuringia - it hit us hard! A structured retrospective review of primary care, the work of nurses and the course of infections Coronavirus disease 19 infection Young Adults (18-44 yrs) Thüringer Hausärzteverband e.V. (THV) Germany 2020-05-18 91963/2020/50, DRKS00022035 Phase Not Applicable Recruiting 1 100 Mr. Dr. Ulf Zitterbart 2020-06-29
A phase II/III trial of BC-007 in patients with COVID-19 Coronavirus disease 19 infection BC-007 alone Beta 1 adrenoceptor modulator, COVID19 Spike glycoprotein modulator Berlin Cures GmbH 2020-12-31 Phase 2/Phase 3 Clinical Planned 0 2020-06-26
Self-sampling for the Study of COVID-19 Coronavirus disease 19 infection Atila BioSystems iAMP COVID-19 Detection Kit assay alone, anterior nare self-sampling alone, mid-turbinate self-sampling alone, saliva self-sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Medical College of Wisconsin US 2020-07-01 2020-12-31 20-001, NCT04447495 Phase Not Applicable Not yet recruiting 1 6 Months 500 Juan Felix, M.D. 2020-06-29
ICI LOLA: Imaging SARS-CoV-2 Involvement of Leptomeninges, Olfactory and Limbic Areas Coronavirus disease 19 infection, Neoplastic meningitis, Neurological disease, Olfaction disorder MRI alone, gadolinium alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fondation Ophtalmologique Adolf De Rothschild France 2020-05-20 2021-11-20 2020-A01216-33, ICI LOLA, NCT04448054 Phase Not Applicable Recruiting 1 18 Months 100 Amélie YAVCHITZ, Guillaume POILLON 2020-06-30
Ayurveda and Yoga trial for preventing COVID 19 among quarantined individuals exposed to COVID 19 patients Coronavirus disease 19 infection, Psychotic disorder standard prophylactic measure alone, yoga alone, Nishamalaki Churna plus Samshamani Vati Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences India 2020-06-10 CTRI/2020/06/026147 Phase 2/Phase 3 Clinical Not yet recruiting 1 604 Dr Gautam Sharma 2020-06-29
Ayurveda and Yoga trial for preventing COVID-19 among healthcare workers Coronavirus disease 19 infection, Psychiatric disorder Mindfulness based Yoga module alone, Standard prophylactic mneasures alone, Kalamegha tablet plus Samshamani Vati Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) All India Institute of Medical Sciences India 2020-06-10 CTRI/2020/06/026151 Phase 2 Clinical Not yet recruiting 1 452 Dr Gautam Sharma 2020-06-29
A study to assess the efficacy and safety of MemVax Vaccine in the treatment of covid-19 Coronavirus disease 19 infection MemVax alone CD40 ligand receptor agonist Healthy volunteers accepted Memgen LLC Phase Not Applicable Planned 0 2020-06-26
Mesenchymal Stromal Cell Therapy For The Treatment Of Acute Respiratory Distress Syndrome Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory insufficiency KI-MSC-PL-205 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Uppsala University Sweden 2020-06-17 2025-06-30 2020-02238, ARDS-MSC-205, NCT04447833 Phase 1 Clinical Recruiting 1 60 Months 9 Karl-Henrik Grinnemo, MD, PhD, Oscar Simonsson, MD, PhD 2020-07-01
Covid-19 pneumonia Coronavirus disease 19 infection, Viral pneumonia HOSPITAL RAJA PEREMPUAN ZAINAB II Malaysia 2020-06-25 2020-07-30 55488, NMRR-20-1236-55488 Phase Not Applicable Status not specified 1 1 Month Dr Abdul Karim Bin Othman, Dr Mohd Nazri Ali 2020-06-29
Determinants of SARS-COV2 (COVID-19) Persistence After Convalescence Coronavirus disease 19 infection Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Columbia University US 2020-03-26 2021-03-01 AAAS9722, NCT04448145 Phase Not Applicable Recruiting 1 11 Months 250 Lawrence Purpura, MD, MPH, Michael Yin, MD, MS 2020-06-29
Percutaneous Tracheostomy With COVID-19 Coronavirus disease 19 infection aerosol box alone, percutaneous tracheostomy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Canakkale Onsekiz Mart University Turkey 2020-03-20 2020-06-01 NCT04447638, TT17 Phase Not Applicable Completed 1 2 Months 12 Mesut ERBAS 2020-06-29
A clinical trial of anti-SARS-CoV-2 program (COVID-19), NanoViricides for the potential treatment of COVID-19 infection Coronavirus disease 19 infection anti-SARS-CoV-2 program (COVID-19), NanoViricides alone NanoViricides Inc Phase Not Applicable Planned 0 2020-06-26
Study of Mavrilimumab (KPL-301) in Participants Hospitalized With Severe Corona Virus Disease 2019 (COVID-19) Pneumonia and Hyper-inflammation Coronavirus disease 19 infection, Lung inflammation, Viral pneumonia mavrilimumab alone, standard of care therapy alone C-reactive protein inhibitor, Chemokine CC22 ligand inhibitor, GM-CSF receptor antagonist, Hemoglobin scavenger receptor antagonist, Metalloprotease-1 inhibitor, Metalloprotease-3 inhibitor, Small inducible cytokine A17 ligand inhibitor, VEGF gene inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kiniksa Pharmaceuticals Ltd US 2020-06-30 2021-04-30 KPL-301-C203, NCT04447469 Phase 2/Phase 3 Clinical Not yet recruiting 1 10 Months 573 Joshua Denson, MD, Kiniksa Clinical Research Team 2020-06-29
CoDDYC: Dietary Diversity of Young Children During COVID-19 Outbreak: A Longitudinal Study Coronavirus disease 19 infection, Nutritional deficiency IYC feeding practice-dietary counseling alone Healthy volunteers accepted, Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs) University of Malaya Malaysia 2020-06-06 2021-05-31 2020410-8500, CoDDYC, NCT04447209 Phase Not Applicable Recruiting 1 11 Months 300 Hazreen A Majid, BSc MND PhD, Lucy CS Lum, MBBS, MRCP, Lucy Lum Chai See, Lucy Lum, MBBS, MRCP, Mohamad Y Jalaludin, MBBS, MPaeds, Mohammad Y Jalaludin, MBBS MPaeds, Yin M Choo, MBBS 2020-06-29
A phase I trial of SARS-CoV-2 mRNA vaccine for potential treatment of COVID-19 Coronavirus disease 19 infection SARS-CoV-2 mRNA vaccine (COVID-19), Sanofi Pasteur/ Translate Bio alone Sanofi SA Translate Bio MA Inc 2020-12-31 Phase 1 Clinical Planned 0 2020-06-29
A phase I/II clinical trial of recombinant protein-based​ vaccine for potential treatment of COVID-19 Coronavirus disease 19 infection recombinant protein vaccine (COVID-19), UMN Pharma Inc alone Sanofi SA GlaxoSmithKline plc Phase 1/Phase 2 Clinical Planned 0 2020-06-26
Impact of the COVID-19 Pandemic and HRQOL in Cancer Patients and Survivors Anxiety disorder, Cancer, Coronavirus disease 19 infection, Depression online survey alone Healthy volunteers accepted MD Anderson Cancer Center National Cancer Institute US 2020-05-12 2021-07-21 2020-0425, NCI-2020-03900, NCT04447222, P30CA016672 Phase Not Applicable Recruiting 1 14 Months 1242 Lorenzo Cohen 2020-07-01
The Impact of COVID-19 Outbreak on Trans-population's Health in Italy Coronavirus disease 19 infection, Transsexualism web based survey alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Unita Complessa di Ostetricia e Ginecologia Italy 2020-05-20 2020-11-20 NCT04448418, TRANSCOVID-19 Phase Not Applicable Recruiting 1 6 Months 300 Giulia Gava, M.D., maria cristina meriggiola 2020-06-29
Effect of COVID-19 on Platelet Aggregation Coronavirus disease 19 infection, Influenza virus infection, Respiratory disease peripheral vein venipuncture alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Sao Paulo Fundacao de Amparo a Pesquisa do Estado Sao Paulo Brazil 2020-04-29 2020-12-30 NCT04447131, SDC 5089/20/118 Phase Not Applicable Recruiting 1 8 Months 200 Jose Carlos Nicolau, José Carlos Nicolau 2020-06-29
DUR-928 in Subjects With SARS-CoV-2 With Acute Liver or Kidney Injury Coronavirus disease 19 infection, Liver injury, Renal injury DUR-928 (injectable, renal injury/psoriasis/alcoholic hepatitis), DURECT Corp alone, standard of care therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) DURECT Corp US 2020-06-30 2021-01-31 C928-020, NCT04447404 Phase 2 Clinical Recruiting 3 7 Months 80 Deborah Scott, Julie Fergus, Robert Gordon, MD 2020-07-03
TITAN: Early Treatment With Ivermectin and Losartan for Cancer Patients With COVID-19 Infection Advanced solid tumor, Coronavirus disease 19 infection, Hematological neoplasm ivermectin plus losartan Angiotensin II AT-1 receptor antagonist, Angiotensin II receptor antagonist, Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto do Cancer do Estado de São Paulo Brazil 2020-07-31 2021-02-28 NCT04447235, NP 1677/20, TITAN Phase 2 Clinical Not yet recruiting 1 7 Months 176 Maria del Pilar Diz, MD, PhD, Pedro Exman, MD 2020-06-29
PRECOV: A randomized, controlled clinical trial on the effects of hydroxychloroquine in the prevention of COVID-19 in healthcare workers at risk Coronavirus disease 19 infection hydroxychloroquine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Istituto Scientifico H San Raffaele Italy 2020-05-06 2020-001987-28, PRECOV, PRECOV Phase 3 Clinical Recruiting 1 1000 IRCCS Ospedale San Raffaele 2020-06-29
ARCO-Homestudy: Adaptive, Randomized trial for therapy of Coronavirus disease 2019 at home with oral antivirals Coronavirus disease 19 infection Plaquenil alone, darunavir + cobicistat (fixed dose, HIV infection), Janssen R&D/ Gilead alone, favipiravir alone, lopinavir + ritonavir alone Cytochrome P450 3 inhibitor, HIV protease inhibitor, HIV-1 protease inhibitor, RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Istituto Nazionale Per Le Malattie Infettive "Lazzaro Spallanzani" Italy 2020-05-14 2020-001528-32, ARCO-Homestudy, ARCO-Homestudy Phase 3 Clinical Recruiting 1 435 Dipartimento di Epidemiologia Digno 2020-06-29
ESCAPE: A phase III, randomized, open-labeled, multicenter study comparing clinical efficacy and safety of intravenous sarilumab plus standard of care compared to standard of care, in the treatment of patients with severe COVID-19 pneumonia Coronavirus disease 19 infection, Inflammatory disease, Viral pneumonia sarilumab alone, standard of care alone IL-6 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Istituto Nazionale Per Le Malattie Infettive "Lazzaro Spallanzani" Italy 2020-04-27 2020-001390-76, ESCAPE, ESCAPE Phase 3 Clinical Recruiting 1 171 Immunodeficienze virali 2020-06-29
An adaptive, phase II, randomized, placebo-controlled study to evaluate the safety and efficacy of PL8177 in the treatment of hospitalized adult COVID-19 patients with hypoxemic respiratory failure, with or without mild acute respiratory distress syndrome (ARDS) Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure PL-8177 alone, standard of care alone Melanocortin MC1 receptor agonist Palatin Technologies Inc 2020-12-31 Phase 2 Clinical Planned 0 176 2020-06-26
Maintaining the health of people with and without COVID-19 during isolation Anxiety disorder, Coronavirus disease 19 infection, Lung disease, Upper respiratory tract infection PhysiApp alone, PhysiTrack software alone, Sydney local health district service alone, UberEats alone, anxiety management technique alone, exercise program alone, nutritional advice alone, paper-based exercise program alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Royal Prince Alfred Hospital Australia 2020-06-10 2020-12-16 ACTRN12620000698976 Phase Not Applicable Recruiting 1 6 Months 40 Prof Jennifer Alison 2020-06-29
An exploratory, non-randomized, open-label, single-arm study to evaluate the safety of ADR-001 in patients with severe pulmonary inflammation caused by SARS-CoV-2 infection Coronavirus disease 19 infection, Lung inflammation, Viral pneumonia ADR-001 alone Rohto Pharmaceutical Co Ltd Japan 2020-08-31 2021-12-31 Phase Not Applicable Planned 1 16 Months 6 2020-06-25
A study to assess the effect of gelsolin, BioAegis Therapeutics in patients with COVID-19 pneumonia Coronavirus disease 19 infection, Viral pneumonia gelsolin, BioAegis Therapeutics alone Actin antagonist BioAegis Therapeutics Inc US Phase Not Applicable Planned 1 2020-06-25
Atrial Fibrillation in Patients with an Implantable Cardiac Device during the COVID-19 Pandemic Atrial fibrillation, Coronavirus disease 19 infection PaceMate remote monitoring system alone, implantable cardioverter defibrillator alone, permanent pacemaker alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Adelaide US 2020-06-24 2020-06-25 ACTRN12620000692932p Phase Not Applicable Not yet recruiting 1 1000 Prof Prashanthan Sanders 2020-06-29
A clinical study of virus-neutralizing antibody therapeutic (COVID19), Kaneka in Coronavirus disease 19 infection Coronavirus disease 19 infection virus-neutralizing antibody therapeutic (COVID19), Kaneka alone Kaneka Corp Tokyo University of Science Phase Not Applicable Planned 0 2020-06-25
Comparing the user seal check and fit test between two types of N95 respirators: the Halyard N95 Particulate Filter Respirators and the ProShield N-95 masks Coronavirus disease 19 infection PortaCount machine alone, ProShield N-95 mask alone, quantitative fit test alone, user seal check alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry, Japanese Ancestry Royal Melbourne Hospital Australia 2020-06-02 2020-06-05 ACTRN12620000688987, U1111-1252-2924 Phase Not Applicable Completed 1 96 Prof Daryl Williams 2020-07-01
Effectiveness of Elman tablet on COVID-19 infection severity Coronavirus disease 19 infection Variable regimens including Elman (Simorgh Attar Neishabour Pharmaceutical) , hydroxychloroquine , lopinavir + ritonavir HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Esfarayen Faculty of Medical Sciences Iran 2020-07-09 IR.ESFARAYENUMS.REC.1399.003, IRCT20200609047707N1 Phase 3 Clinical Recruiting 1 90 Eshagh Ildarabadi, Essa Tohidi, Seyed Javad Hosseini 2020-07-09
CHLORAZ: An Observational Study to Assess the Protocol for the COVID-19 Treatment in Burkina Faso Coronavirus disease 19 infection Variable regimens including azithromycin , chloroquine phosphate , hydroxychloroquine Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Muraz Burkina Faso 2020-04-24 2020-12-31 CHLORAZ, IRSS-URCN-CM 001, NCT04445441 Phase Not Applicable Recruiting 2 8 Months 150 Espérance Ouédraogo, MD, Msc, Halidou Tinto, PhD, Houreratou Barry, MD, Msc, Innocent Valea, PhD, Marc Tahita, PhD 2020-07-03
KAP of New Normal Among HCW in Hospital Kuala Lumpur and Hospital Sungai Buloh Regarding COVID-19 Coronavirus disease 19 infection University of Malaya 2020-07-01 2021-06-30 55330, NMRR-20-1212-55330 Phase Not Applicable Status not specified 0 12 Months Dr Sri Viknarajan A/L Puvendran 2020-06-26
Modelling of COVID-19 in Malaysia Coronavirus disease 19 infection University of Malaya Malaysia 2020-06-22 2020-12-31 55087, NMRR-20-1208-55087 Phase Not Applicable Status not specified 1 6 Months Dr Vivek Jason a/l Jayaraj 2020-06-26
COVID-19 infected HCW Coronavirus disease 19 infection Hospital Queen Elizabeth Malaysia 2020-08-01 2021-07-31 55463, NMRR-20-1207-55463 Phase Not Applicable Status not specified 1 12 Months Dr Hor Chee Peng, Ms. Teong Win Zee 2020-06-26
Phase I Clinical Study of Recombinant Novel Coronavirus Vaccine Coronavirus disease 19 infection recombinant new coronavirus vaccine (CHO cell) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Anhui Zhifei Longcom Biopharmaceutical Co Ltd Beijing Chao-Yang Hospital, The Second Affiliated Hospital, Chongqing Medical University China 2020-06-22 2021-09-20 NCT04445194, NCV-I-HEALTHY Phase 1 Clinical Recruiting 1 14 Months 50 Hong Ren, doctor, Hong Ren, master 2020-07-03
NOCoV2: A Study to Assess Efficacy and Safety of RESP-301 Plus Standard of Care (SOC) Compared to SOC Alone in Hospitalized Participants With COVID-19 Coronavirus disease 19 infection RESP-301 alone, standard handheld nebulizer treatment alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Thirty Respiratory Limited Spain, Netherlands, Germany, UK, Italy, France, US 2020-07-06 2021-04-23 2020-002120-37, NCT04460183, NOCoV2, RESP301-002 Phase 2/Phase 3 Clinical Not yet recruiting 8 9 Months 300 Clinical department, Kate L McKeown, PhD, Onn M Kon 2020-07-08
Measles Vaccine: Is There a Protective Role in COVID-19 Pandemic? Coronavirus disease 19 infection measles vaccine alone Ain Shams University Egypt 2020-07-01 2020-11-01 FMASU P31A/ 2020, NCT04445610 Phase Not Applicable Not yet recruiting 1 4 Months 60 Amira Al Balakosy, M.D, Amira Al Balakosy, MD 2020-07-01
A clinical study to assess the benefits of measles, mumps, rubella (MMR) vaccine as a protection against COVID-19 Coronavirus disease 19 infection MMR vaccine alone American Society for Microbiology US Phase Not Applicable Planned 1 Fidel, Noverr 2020-06-25
CO-FLOW: COVID-19 Follow-up care paths and Long-term Outcomes Within the Dutch health care system: a combined rehabilitation, pulmonary, and intensive care perspective Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Erasmus University Medical Center Rotterdam Netherlands 2020-07-01 2023-07-01 CO-FLOW, MEC 2020-0487, NL8710 Phase Not Applicable Not yet recruiting 1 36 Months 335 Majanka Heijenbrok-Kal 2020-06-29
ANTI-CO: Anticoagulation in Patients Suffering From COVID-19 Disease - The ANTI-CO Trial Coronavirus disease 19 infection, Respiratory failure bivalirudin alone Factor IIa antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hamad Medical Corp Qatar 2020-06-28 2021-03-28 ANTI-CO, MRC-05-082, NCT04445935 Phase 4 Clinical Recruiting 1 9 Months 100 Dr. Marcus Daniel Lance, Marcus Lance, MD, PhD, Nadir Kharma, MD, Stefan Roehrig, MD, MBA 2020-06-30
EPISODE-PS-COV: Head Pulse for Ischemic Stroke Detection Prehospital Study During the COVID-19 Pandemic Coronavirus disease 19 infection, Ischemic stroke Cranial accelerometry alone, Head pulse recording alone, MindRhythm Harmony alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) MindRhythm, Inc. Wayne State University 2020-07-31 2021-06-30 EPISODE-PH-COVID, EPISODE-PS-COV, NCT04445493 Phase Not Applicable Not yet recruiting 0 11 Months 250 Lisa Distenfield, Paul Lovoi, Ph.D 2020-07-07
A study to understand differences in individual risk factors for COVID-19 Coronavirus disease 19 infection Microdrop LLC Phase Not Applicable Status not specified 0 2020-06-26
Study of the Treatment and Outcomes in Critically Ill Patients With COVID-19 and High Risk of Acute Kidney Injury Coronavirus disease 19 infection, Renal injury Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Guy's & St Thomas' Hospital NHS Trust Harvard Medical School UK 2020-06-20 2021-05-31 283672, NCT04445259 Phase Not Applicable Recruiting 1 11 Months 300 Marlies Ostermann, MD, PhD, Nuttha Lumlertgul, MD, PhD 2020-07-02
Unraveling the Mechanisms of Olfactory Dysfunction in COVID-19 Coronavirus disease 19 infection, Dysomia, Olfaction disorder tissue sampling alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Universitaire Ziekenhuizen Leuven Max Planck Institute for Neurological Research Belgium 2020-05-07 2020-06-30 NCT04445597, S64042 Phase Not Applicable Recruiting 1 1 Month 8 Laura Van Gerven, Laura Van Gerven, Doctor, Wout Backaert 2020-06-26
Mesenchymal Stromal Cell Therapy for Severe Covid-19 Infection Coronavirus disease 19 infection, Inflammatory disease, Viral pneumonia mesenchymal stromal cells alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Liege Belgium 2020-06-12 2022-09-30 NCT04445454, TJT2012 Phase 1/Phase 2 Clinical Recruiting 1 27 Months 20 Audrey Janssen, Benoit Misset, MD,PhD, Bernard Lambermont, MD,PhD, Gilles Darcis, MD,PhD, Michel Moutschen, MD,PhD, Nathalie Layios, MD, Yves Beguin, Yves Beguin, MD,PhD 2020-06-26
ONCOCARE-COV: Oncology Care Pathway's Modifications Impact During COVID-19 Pandemic Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire de Reims France 2020-05-01 2020-12-31 2020AO001*, NCT04445870, ONCOCARE-COV Phase Not Applicable Recruiting 1 8 Months 100 Damien JOLLY, Mathias BRUGEL 2020-06-30
SCIL_COV19: SCIL-1Ra in COVID-19 Feasibility And Pharmacokinetics/Pharmacodynamics Coronavirus disease 19 infection, Inflammatory disease anakinra alone Type I IL-1 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Manchester UK 2020-05-28 2020-09-30 2020-001636-95, 282110, NCT04462757, SCIL_COV19 Phase 2 Clinical Recruiting 3 4 Months 40 Jonathan Bannard-Smith, Dr, Paul M Dark, Prof, Rachel Cox, Safia Barber, Timothy Felton, Dr 2020-07-09
Antiphospholipid Antibody (APLA) level in COVID-19 Cases Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) KIMS Hospital India 2020-08-01 CTRI/2020/06/026118 Phase Not Applicable Not yet recruiting 1 80 Dr Rajlaxmi Sarangi 2020-06-26
CO-HOST: COVID-19 Household Transmission Study Coronavirus disease 19 infection biological sampling alone Healthy volunteers accepted, Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of North Carolina North Carolina Translational and Clinical Sciences Institute US 2020-04-29 2020-12-31 20-0982, 550KR242023, CO-HOST, NCT04445233 Phase Not Applicable Recruiting 1 8 Months 400 Carla Cerami, MD, PhD, Christopher Basham, BS, MSc, David Wohl, MD, Jessica Lin, MD, MSCR, Jonathan Juliano, MD, MSPH 2020-06-26
Pediatrics HOT COVID-19 Database in NY Tristate Coronavirus disease 19 infection, Neoplasm, Neurological disease, Sickle cell anemia, Stem cell transplantation Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Columbia University US 2020-04-30 2022-05-01 AAAT0268, NCT04445402 Phase Not Applicable Recruiting 17 24 Months 1500 Alex Chou, MD, Alissa Kahn, MD, Andrea Orsey, MD, Archana Sharma, Jean Sosna, MS RN, Jeffrey Lipton, MD, Jennifer Krajewski, Jennifer Levine, MD, Jessica Hochberg, MD, Joanna Pierro, MD, Katie Devine, Laura Hogan, MD, Marianna DeBenedictis, MD, Nina Kadan-Lottick, MD, Pallavi Madhusoodhan, MD, Prakash Satwani, MD, Stephen Roberts, Steven Halpern 2020-06-26
COVID-VENT: Respiratory Mechanics and Gas Exchange in Patients With COVID-19 and Hypoxemic Acute Respiratory Failure Coronavirus disease 19 infection, Hypoxia, Respiratory failure gas exchange measurement alone, respiratory mechanics measurement alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) IM Sechenov Moscow Medical Academy Russian Federation 2020-05-01 2020-08-31 COVID-VENT, COVID-VENT, NCT04445961 Phase Not Applicable Recruiting 1 4 Months 70 Andrey I Yaroshetskiy, Dr.Med.Sc., Mikhail E Politov, PhD, Pavel V Nogtev, PhD, Sergey N Avdeev, Prof, Yury D Sorokin, PhD 2020-06-26
Treatment with Omega-3 polyunsaturated fatty acids in COVID-19 patients: A single-blind, randomized, placebo-controlled, feasibility study Coronavirus disease 19 infection, Inflammatory disease Omegaven alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Karolinska University Hospital Swedish Heart Lung Foundation, Swedish Research Council Sweden 2020-05-29 2020-002293-28 Phase 2 Clinical Recruiting 1 20 Co-ordinating investigator 2020-06-26
Phase II, randomized, controlled, open-label study of Pegylated IFN alfa-2b with SARS-CoV-2 Coronavirus disease 19 infection Pegylated IFN alfa-2b alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Zydus-Cadila Group India 2020-07-10 CTRI/2020/06/026087, PEGI.20.002 Phase 2 Clinical Not yet recruiting 1 40 Dr Anuja Pandit, Dr Kevinkumar Kansagra 2020-06-26
An interventional study to access the effect of Homoeopathic medicine Arsenicum album 30 C as a prohylaxis in high risk population exposed to COVID-19 Coronavirus disease 19 infection Arsenicum album 30 C alone Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ministry of Ayush India 2020-06-26 CTRI/2020/06/026056 Phase 3 Clinical Not yet recruiting 1 5000 Dr Tapan Nath, Prof PK Goswami 2020-06-26
CovidImmunEye: Immune Status SARS-CoV-2 in a Sample of a Tertiary Eye Health Centre Coronavirus disease 19 infection ELISA test alone, Rapid test alone Healthy volunteers accepted University Hospital Tubingen Klinikum rechts der Isar der Technischen Universitaet Muenchen Germany 2020-05-13 2020-08-31 292/2020BO2, CovidImmunEye, NCT04446338 Phase Not Applicable Recruiting 2 3 Months 300 Focke Ziemssen, Focke Ziemssen, MD, Tarek Bayyoud, MD 2020-06-26
An interventional study to access the effect of Ayurvedic medicine ASA-20 as a prohylaxis in high risk population exposed to COVID-19 Coronavirus disease 19 infection ASA-20 alone Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ministry of Ayush India 2020-06-26 CTRI/2020/06/026055 Phase 3 Clinical Not yet recruiting 1 5000 Dr Sikha Lekharu, Prof Dr P K Goswami 2020-06-26
A phase II, randomized, controlled, multicenter to evaluate the safety, tolerability, and effectiveness of OT-101 in combination with standard of care (SoC) in hospitalized COVID-19 patients Coronavirus disease 19 infection standard of care (SoC) alone, trabedersen alone TGFB2 gene inhibitor Mateon Therapeutics Inc IQVIA Holdings Inc Phase 2 Clinical Planned 0 2020-06-25
PARTISAN: Prasugrel in Severe COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia prasugrel alone P2Y12 purinoceptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Azienda Ospedaliera Universitaria Integrata Di Verona Universita degli Studi di Milano Italy 2020-07-31 2021-01-31 MGI-COVID-19-PRASUGREL, NCT04445623, PARTISAN Phase 3 Clinical Not yet recruiting 1 6 Months 128 Marco Cattaneo, Professor, Pietro Minuz, Professor 2020-06-29
ILOCOVID: Inhaled Iloprost for Suspected COVID-19 Respiratory Failure Coronavirus disease 19 infection, Hypoxia, Respiratory failure iloprost (inhaled nebulizer formulation, pulmonary hypertension), Bayer Schering/Actelion alone PGI2 agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hamad Medical Corp Qatar 2020-05-23 2021-05-31 ILOCOVID, MRC-05-026, NCT04445246 Phase 2 Clinical Recruiting 1 12 Months 40 Ali AitHssain, MD, Nadir Kharma, MD 2020-06-26
A Study of LAM-002A for the Prevention of Progression of COVID-19 Coronavirus disease 19 infection apilimod dimesylate (capsule, B-cell non-Hodgkins lymphoma/Chronic lymphocytic leukemia/amyotrophic lateral sclerosis), AI Therapeutics alone FYVE finger phosphoinositide kinase inhibitor, IL-12 receptor antagonist, IL-23 antagonist, Transcription factor EB stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) AI Therapeutics Yale University US 2020-06-29 2021-01-31 LAM-002A-CVD-CLN01, NCT04446377 Phase 2 Clinical Not yet recruiting 1 7 Months 142 Charles Dela Cruz, MD, Ph.D, Peter Young, PhD 2020-06-26
Ivermectin in Treatment of COVID-19 Coronavirus disease 19 infection ivermectin alone, standard of care alone Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Zagazig University Egypt 2020-05-31 2020-08-15 NCT04445311, ZU-IRB-6151/31-5-2020 Phase 2/Phase 3 Clinical Recruiting 1 2 Months 100 Waheed Shouman, Waheed Shouman, MD 2020-06-26
VIRCO: An Adaptive, Randomized, Placebo-Controlled, Phase II Trial of Antivirals for COVID-19 Infection Coronavirus disease 19 infection favipiravir alone, usual standard of care alone RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bayside Health 2020-07-31 2020-11-30 66223, NCT04445467, VIRCO Phase 2 Clinical Not yet recruiting 0 4 Months 190 James McMahon, Janine Roney 2020-06-26
Short Term Corticosteroids in SARS-CoV2 Patients Coronavirus disease 19 infection, Hypoxia, Viral pneumonia dexamethasone alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Miriam Hospital US 2020-04-01 2020-05-31 20-027, NCT04445506 Phase Not Applicable Completed 1 2 Months 50 Kwame Dapaah-Afriyie, MD 2020-06-26
Experimental Expanded Access Treatment With Convalescent Plasma for the Treatment of Patients With COVID-19 Coronavirus disease 19 infection, Respiratory failure convalescent COVID-19 plasma alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Massachusetts, Worcester US H000020420, NCT04445207 Phase Not Applicable Recruiting 1 Cara Gregoire, Jonathan Gerber, Jonathan Gerber, MD, Principal Investigator 2020-06-26
A study to improve the resistance against Covid-19 illness with the help of Homoeopathic remedies Coronavirus disease 19 infection homoeopathic medicine therapy alone Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Father Muller Homoeopathic Medical College India 2020-07-01 CTRI/2020/06/026045 Phase 3 Clinical Not yet recruiting 1 800 Dr Dilip B Dikshit, Dr M K Kamath 2020-07-08
Oral Fluid Sars-CoV-2 Ab Rapid test Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Asian Healthcare Foundation India 2020-07-04 CTRI/2020/06/026044, OFST19 Phase Not Applicable Not yet recruiting 1 100 Naveen Chander Reddy P, Sasikala Mitnala, Vishnupriya Rao Paturi 2020-06-26
DAMPEN COVID: Phase II Trial Using rhDNase to Reduce Mortality in COVID-19 Patients With Respiratory Failure Coronavirus disease 19 infection, Respiratory failure dornase alfa alone Deoxyribonuclease I stimulator, Deoxyribonuclease stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of South Alabama US 2020-04-28 2020-07-31 DAMPEN COVID, NCT04445285, USAH 1002 000 Phase 2 Clinical Recruiting 1 3 Months 44 Jon D Simmons, M.D., Jon Simmons, Jon Simmons, M.D., Wendy Blount, RN, MSN 2020-06-26
The Effect of Inspiratory muscle training in patients with COVID-19 Coronavirus disease 19 infection Inspiratory muscle training device alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Shahid Beheshti University of Medical Sciences, Laser Application in Medical Sciences Research Center Iran 2020-07-22 IR.SBMU.NRITLD.REC.1399.088, IRCT20200611047727N1 Phase Not Applicable Not yet recruiting 1 40 Atefeh Fakharian, Maryam Mirenayat, Saba Karimzade 2020-06-26
HERD: Protection of Health Workers Against COVID-19 Coronavirus disease 19 infection, Respiratory disease Previfenon alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) MELISA Institute Genomics & Proteomics Research SpA Universidad Austral De Chile Chile 2020-07-30 2020-11-30 HERD, MEL109042020, NCT04446065 Phase 2/Phase 3 Clinical Not yet recruiting 1 4 Months 524 Cristian Vargas, MD, Elard Koch, PhD, Head of Reserach, Elard S Koch, PhD, Miguel A Bravo, MPH 2020-06-26
A diagnostic study comparing different tests for the diagnosis of COVID-19 Coronavirus disease 19 infection RT-PCR alone, nasopharyngeal swab test alone, serological test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) IRCCS Sacro Cuore Don Calabria hospital Ministero della Salute Italy 2020-02-26 2020-05-25 ISRCTN13990999 Phase Not Applicable Completed 1 3 Months 400 Prof Bisoffi 2020-06-26
Diagnostic Value of New COVID-19 Antibodies Testing Among Laboratory Healthcare Workers Coronavirus disease 19 infection Covid-19 antibody testing alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Assiut University Egypt 2020-07-01 2021-09-01 COVID-19 ANTIBODIES TESTING, NCT04445415 Phase Not Applicable Not yet recruiting 1 14 Months 250 Azza Ezzeldin, Professor, Samar Salah Eldin, Samar Salah Eldin Abdelrahman Sultan 2020-06-29
Anti-Androgen Treatment for COVID-19 Alopecia, Coronavirus disease 19 infection Variable regimens including azithromycin , dutasteride , ivermectin 5-Alpha-reductase inhibitor, 5-Alpha-reductase-1 inhibitor, 5-Alpha-reductase-2 inhibitor, Chloride channel modulator Male, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Applied Biology Inc Corpometria Institute, Warren Alpert Medical School of Brown University Brazil 2020-06-26 2021-01-31 AB-DRUG-SARS-004, NCT04446429 Phase 2 Clinical Not yet recruiting 1 7 Months 254 Andy Goren, MD, Carlos G. Wambier, Carlos Wambier, MD, Flavio A Cadegiani, MD, John McCoy 2020-06-29
COVID-19 (SARS-CoV-2) in Urine and Semen Coronavirus disease 19 infection, Genital tract infection PCR test alone Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universita degli Studi di Firenze Azienda Ospedaliera Careggi Italy 2020-06-27 2020-08-12 17104_OSS/2020, NCT04446169 Phase Not Applicable Recruiting 1 1 Month 50 Alberto Antonelli, MD, Alessandro Bartoloni, Prof, Arcangelo Sebastianelli, MD, Claudia Zaccaro, MD, Filippo Lagi, MD, Gian Maria Rossolini, Prof, Mauro Gacci, MD, Saverio Giancane, MD, Sergio Serni, Prof, Silvia Benemei, PhD, Simona Pollini, MD, Simone Morselli, Simone Morselli, MD 2020-07-03
ECMO-SL-CoV-2: Bicentric Study on the Use of ECMO-VV or VA for Severe ARDS Associated With Covid-19 Coronavirus disease 19 infection, Respiratory distress syndrome veno-arterial extracorporeal membrane oxygenation therapy alone, veno-venous extracorporeal membrane oxygenation therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopitaux Universitaires de Strasbourg France 2020-06-18 2020-07-18 7904, ECMO-SL-CoV-2, NCT04446286 Phase Not Applicable Recruiting 1 1 Month 50 Anne OLLAND, MD, PhD, Bart MEYNS, MD, PhD, Jean-Philipe MAZZUCOTELLI, MD, PhD, Leen VERCAEMST, MD, Marc PUYRAVEAU, MD, Marion VILLARD, MD, Pierre-Emmanuel FALCOZ, MD, PhD, Saïd CHAYER, PhD, HDR 2020-07-02
OPV as Potential Protection Against COVID Coronavirus disease 19 infection COVID-19 protection advice alone, bivalent oral polio vaccine (GSK) alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bandim Health Project Guinea-Bissau 2020-07-31 2021-06-30 77/CNES/INASA/2020, NCT04445428 Phase 4 Clinical Not yet recruiting 1 11 Months 3400 Ane Fisker, MD, PhD 2020-06-29
A Study of Cell Therapy in COVID-19 Subjects With Acute Kidney Injury Who Are Receiving Renal Replacement Therapy Coronavirus disease 19 infection, Renal injury SBI-101 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sentien Biotechnologies 2020-08-31 2021-07-31 NCT04445220, SBI-101-02 Phase 1/Phase 2 Clinical Not yet recruiting 0 11 Months 24 Brian Miller 2020-06-26
PLATINA trial: Plasma therapy in corona patients (Severe COVID-19) Coronavirus disease 19 infection Convalscent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Government Medical College, Nagpur India 2020-06-25 CTRI/2020/06/026123, PLATINA trial Phase 2 Clinical Not yet recruiting 16 472 Dr Anita Bandichhode, Dr Anita Basavaraj, Dr Baba Yelke, Dr D P Bhurke, Dr Deepak Shejwal, Dr Mahendrakumar V Bansode, Dr Maroti Karale, Dr Minakshi Bhattacharya, Dr Prasad Potdukhe, Dr Radha Munje, Dr Rohidas Borse, Dr Sanjay Chawhan, Dr Sheshrao S Chavan, Dr Sunita Ade, Dr Sushant Meshram, Dr Vidya Nagar, Dr Vijay Gaikwad 2020-06-26
Safety and Immunogenicity Study of GX-19, a COVID-19 Preventive DNA Vaccine in Healthy Adults Coronavirus disease 19 infection GX-19 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Genexine Co Ltd South Korea 2020-06-17 2022-06-17 GX-19-HV-001, NCT04445389 Phase 1/Phase 2 Clinical Recruiting 1 24 Months 190 Jun Yong Choi, MD, JungWon Woo, Ph.D., Wonjin Lee, B.S., Yoon-Jeong Choi, M.S., Young Goo Song, MD 2020-06-27
To Understand Knowledge and Compliance of Hydroxychloroquine Prophylaxis among Health Care Workers during COVID-19 pandemic Coronavirus disease 19 infection hydroxychloroquine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Sanjay Gandhi Postgraduate Institute of Medical Sciences India 2020-07-04 CTRI/2020/06/026121 Phase Not Applicable Not yet recruiting 1 175 Dr Mohan Gurjar 2020-06-26
Changes in smell and taste as clinical presentation in patients with mild to moderate Coronavirus disease Coronavirus disease 19 infection, Dysomia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kalinga Institute of Medical Sciences India 2020-06-24 CTRI/2020/06/026122 Phase Not Applicable Not yet recruiting 1 250 Dr Pradipt Ranjan Sahoo 2020-06-26
Multicenter, open, prospective, randomized, comparative study to study the safety and efficacy of the drug Remdeform (INN: remdesivir), lyophilisate for the preparation of a solution for intravenous administration, 100 mg (Farmasintez JSC, Russia) as part of complex therapy with patients hospitalized with COVID-19 Coronavirus disease 19 infection remdesivir alone COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Pharmasyntez Russian Federation 2020-06-22 2021-01-01 REMVR-2020/I Phase 3 Clinical Status not specified 16 6 Months 300 2020-06-25
Clinical Improvement and COVID-19 Pneumonia Coronavirus disease 19 infection, Tachypnea, Viral pneumonia ozone autohemotherapy alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) L'Institut d Investigacio Biomedica de Girona Spain 2020-03-20 2020-05-26 COVID NETWORKING GROUP, NCT04444531 Phase Not Applicable Completed 1 2 Months 18 Marc Vives 2020-07-08
AGMFMSS: Alterations of Gut Microbiome in the Frontline Medical Staff Under the Stress Acute stress disorder, Coronavirus disease 19 infection 16S rRNA sequencing alone, PCR alone, fecal sampling alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) The First Affiliated Hospital of Xi'an Jiaotong University China 2020-06-22 2020-08-30 AGMFMSS, NCT04443075, XJTU1AF2020LSK-022 Phase Not Applicable Recruiting 1 2 Months 180 Fengjie Gao, M.M., Xiancang Ma, M.D. 2020-06-26
REHCOVER: Reassessement After Hospitalization for Sars-COV-2 Disorder Cardiovascular disease, Coronavirus disease 19 infection, Fibrosis, Liver disease, Metabolic disorder, Neurological disease, Psychiatric disorder, Renal disease, Respiratory failure Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Montpellier France 2020-07-13 2021-07-25 NCT04443257, RECHMPL20-340, REHCOVER Phase Not Applicable Not yet recruiting 1 12 Months 200 Camille ROUBILLE, MD, Camille Roubille, MD 2020-07-10
COVID-19 Vaccine (ChAdOx1 nCoV-19) Trial in South African Adults With and Without HIV-infection Coronavirus disease 19 infection, Respiratory tract infection AZD-1222 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Witwatersrand Bill & Melinda Gates Foundation, Medical Research Council Of South Africa MRC, University of Oxford South Africa 2020-06-24 2021-12-31 CHADOX1 NCOV-19-ZA-PHI/II, NCT04444674, PACTR202006922165132 Phase 1/Phase 2 Clinical Recruiting 6 18 Months 2000 Anthonet Koen, MBCHB, Clare L Cutland, MBBCH, PhD, Erica Lazarus, MBCHB, Karishma Naidoo, Keertan Dheda, MD, PhD, Lee Fairlie, MD, Shabir A Madhi, MD PhD, Shabir A Madhi, MD, PhD, Shaun Barnabas, MD, PhD, Sherman Padayachee, MD, Thabile Msomi 2020-07-10
Efficacy and Safety of Anti-HCV Drugs in the Treatment of COVID-19 Coronavirus disease 19 infection Variable regimens including daclatasvir , hydroxychloroquine , sofosbuvir Hepatitis C virus NS5B polymerase inhibitor, Hepatitis C virus protein NS5A inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Cairo University Egypt 2020-07-31 2020-12-31 CUKA-003, NCT04443725 Phase 2/Phase 3 Clinical Not yet recruiting 1 5 Months 100 Gamal Esmat 2020-06-26
Characterizing the Perioperative Epidemiology of SARS-CoV-2 (COVID-19) Spread for Quality Improvement of Perioperative Infection Control Program Coronavirus disease 19 infection PathTrac (RDB Bioinformatics) collection kit alone, UV-C (Helios, Surfacide) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Iowa US 2020-07-01 2020-08-31 202005391, NCT04443803 Phase Not Applicable Not yet recruiting 1 2 Months 9 Randy Loftus, Randy W Loftus, MD 2020-06-24
Effects of COVID-19-Induced Deconditioning After Long-term High-Intensity Resistance Exercise Coronavirus disease 19 infection, Osteopenia, Osteoporosis, Sarcopenia high-intensity resistance exercise alone Male, Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Erlangen-Nurnberg Medical School Friedrich-Alexander-Universitaet Erlangen-Nuernberg Germany 2020-06-10 2020-12-31 FROST-FU, NCT04444661 Phase Not Applicable No longer recruiting 1 6 Months 21 Wolfgang Kemmler, PhD 2020-07-07
Preeclampsia-like Syndrome Induced by COVID-19: Is it a Real Public Health Issue in Pregnancy During the Pandemic? Coronavirus disease 19 infection, Pre-eclampsia PCR test alone, lung ultrasound alone Female, Young Adults (18-44 yrs) Zeynep Kamil Maternity and Pediatric Research and Training Hospital Turkey 2020-03-15 2020-07-10 70/2020, NCT04443140 Phase Not Applicable Recruiting 1 3 Months 100 Resul Karakus, MD, Resul Karakuş 2020-07-01
Predictors of Mental Well-being During the COVID-19 Pandemic Coronavirus disease 19 infection, Psychiatric disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Oslo Modum Bad Norway 2020-06-22 2020-07-13 NCT04443699, REK125510-12 Phase Not Applicable Not yet recruiting 3 4000 Hoffart Hoffart, PhD, Omid Ebrahimi, Double PhD Candidate, Sara Ebling, Cand.psychol. stud., Sverre Urnes Sverre Urnes, PhD 2020-06-25
Glycine Supplement for Severe COVID-19 Coronavirus disease 19 infection, Viral pneumonia glycine alone, habitual treatment alone Instituto Nacional de Enfermedades Respiratorias Mexico 2020-06-22 2021-06-30 C40-20, NCT04443673 Phase Not Applicable Recruiting 1 12 Months 82 Alejandra R Báez-Saldaña, MD, Cristóbal Guadarrama-Pérez, MD, David Ibarra-Villarreal, MD, Jaime Chávez-Alderete, PhD, Justino Regalado-Pineda, MD, Mario H Vargas, MSc, Mario H. Vargas, MD, MSc 2020-07-07
Information Sources and Their Relationship to Depressive and Anxiety Symptoms During the COVID-19 Pandemic: A Network Study Anxiety disorder, Coronavirus disease 19 infection, Depression Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Oslo Modum Bad Norway 2020-06-22 2020-07-13 NCT04444336, REK125510-16 Phase Not Applicable Not yet recruiting 2 4000 Asle Hoffart, PhD, Omid Ebrahimi, Double PhD Candidate, Omid V. Ebrahimi, Double PhD Candidate, Sverre Urnes Johnson, PhD 2020-07-01
A phase I clinical trial of SARS-CoV-2 protein subunit vaccine for COVID-19 Coronavirus disease 19 infection SARS-CoV-2 protein subunit vaccine (COVID-19), Chongqing Zhifei Biological Products/ Institute of Microbiology, Chinese Academy of Sciences alone COVID19 Spike glycoprotein modulator Institute of Microbiology, CAS Anhui Zhifei Longcom Biopharmaceutical Co Ltd China Phase 1 Clinical Not yet recruiting 1 2020-06-24
Mesenchymal Stem Cell Infusion for COVID-19 Infection Coronavirus disease 19 infection, Multiple organ failure, Respiratory failure, Septic shock, Viral pneumonia Standard care alone, mesenchymal stem cells alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Blood and Marrow Transplant Pakistan 2020-05-01 2020-09-30 NCT04444271, NIBMT-MSC-COVID-2020 Phase 2 Clinical Recruiting 2 5 Months 20 Xanab Akram, Zaineb Akram, xanab akram 2020-07-02
Antibody Responses in Contacts of COVID-19 Patients Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assiut University Egypt 2020-06-15 2020-09-30 ASSIUT13, NCT04444310 Phase Not Applicable No longer recruiting 1 3 Months 100 2020-06-25
BIBS: Brain Imaging in Babies Study Attention deficit hyperactivity disorder, Autism, Central nervous system development disorder, Coronavirus disease 19 infection MRI alone, traditional behavioural assessments alone Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) King's College London Business Ltd UK 2013-04-05 2023-12-31 BIBS, IRAS: 108997, REC 12/LO/2017, NCT04443179 Phase Not Applicable Recruiting 1 128 Months 790 Dr Grainne McAlonan, Gráinne McAlonan, PhD 2020-06-25
Sequelae of Sars-CoV-2 Infections Coronavirus disease 19 infection, Viral pneumonia computer tomography alone, echocardiography alone, electrocardiography alone, pneumologic test alone, spiroergometry alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Giessen Germany 2020-05-20 2023-12-31 NCT04442789, SECOV Phase Not Applicable Recruiting 1 43 Months 30 Khodr Tello, MD, Ulrich Matt, MD, PhD 2020-06-26
Loneliness During Strict and Lifted Social Distancing Protocols Against the COVID-19 Pandemic Anxiety disorder, Coronavirus disease 19 infection, Depression, Psychiatric disorder Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Modum Bad University of Oslo Norway 2020-06-22 2020-07-13 802810-1, NCT04444115 Phase Not Applicable Not yet recruiting 2 10084 Asle Hoffart, Asle Hoffart, PhD, Omid Ebrahimi, Cand Psychol, Sverre Urnes Johnson, PhD 2020-06-26
The effects of self-care cellphone application on stress, anxiety and depression among admitted patients with COVID-19 Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression mobile-based application alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Mashhad University of Medical Sciences Iran 2020-04-26 IR.MUMS.REC.1399.118, IRCT20170922036314N4 Phase 3 Clinical Recruiting 1 112 Dr. Mahnaz Amini, Shokoufeh Aalaei, aalaei shokoufeh 2020-06-25
Status and Predictors of Mental Health Symptoms Among Migrants and Refugees During the COVID-19 Pandemic Anxiety disorder, Coronavirus disease 19 infection, Depression Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Oslo Modum Bad Norway 2020-06-22 2020-07-13 NCT04443764, REK125510 (8) Phase Not Applicable Not yet recruiting 2 287 Asle Hoffart, PhD, KariAnne Vrabel, PhD, Omid Ebrahimi, Mr, Sverre Urnes Johnson, Sverre Urnes Johnson, PhD 2020-06-25
COST-HD: Effect Of Covid-19 On Mental Health In Syrian And Turkish Maintenance Hemodialysis Patients Coronavirus disease 19 infection, Depression Beck Depression Inventory (BDI) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sisli Etfal Hospital Turkey 2020-04-17 2020-05-01 200620, COST-HD, NCT04444557 Phase Not Applicable Completed 1 97 Mustafa Sevinc, MD, Nuri Baris Hasbal 2020-06-26
Screening for Patients Admitted to Ain-Shams University Hospitals for SARS-COV-2 (COVID19) Coronavirus disease 19 infection RT-PCR test alone Ain Shams University Egypt 2020-05-29 2021-12-01 FMASU P29 /2020, NCT04443712 Phase Not Applicable Recruiting 1 18 Months 1900 Fatma Soliman E Ebeid, Samia Girgis 2020-06-26
Do Network Centrality Predict Overall Depression Symptom Reduction With Lifting of Social Distancing Protocols? Coronavirus disease 19 infection, Depression social distancing alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Modum Bad University of Oslo Norway 2020-06-22 2020-07-13 802810-2, NCT04444713 Phase Not Applicable Not yet recruiting 2 10084 Asle Hoffart, PhD, Omid Ebrahimi, CandPsychol, Sverre Urnes Johnson, PhD 2020-06-26
Conjunctival Swab versus Nasopharyngeal Swab in Patients With COVID-19 Coronavirus disease 19 infection conjunctival swab test alone, nasopharyngeal swab test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Medizinische Universität Innsbruck Austria 2020-06-17 2021-03-31 1104/2020, NCT04444596 Phase Not Applicable Recruiting 1 9 Months 100 Claus Zehetner, Dr, Claus Zehetner, Dr., Teresa Rauchegger, Dr, Teresa Rauchegger, Dr. 2020-06-26
INTENSIVE: Registry on NEN Patients and COVID-19 Coronavirus disease 19 infection, Neuroendocrine tumor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) European Institute of Oncology Italy 2020-06-15 2020-12-15 IEO-1291, INTENSIVE, NCT04444401 Phase Not Applicable Recruiting 1 6 Months 50 Cristina Mazzon, Ph.D., Darina Tamayo, PharmSC., Darina Tamayo, PharmSc, Francesca Spada, MD, PhD, Lorenzo Gervaso, MD, Nicola Fazio, M.D., Ph.D., Nicola Fazio, MD, PhD 2020-07-08
RAPID-BRAZIL: A Pragmatic, Randomized, Controlled Trial of Therapeutic Anticoagulation Versus Standard Care as a Rapid Response to COVID-19 Pandemic Coronavirus disease 19 infection, Thromboembolism enoxaparin sodium alone Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo St Michaels Hospital, University of Vermont Medical Center Brazil 2020-06-25 2020-12-31 CAAE: 33109220.7.0000.0068, NCT04444700, RAPID-BRAZIL Phase 3 Clinical Recruiting 1 6 Months 462 Elnara M Negri, MD, PhD, Hassan Rahhal, MD, Heraldo P de Souza, MD, PhD, Peter Juni, MD, FESC 2020-06-25
LapCoVIDSurg: COVID 19: Is SARS-CoV-2 Contaminating Surgical Aerosols From Laparoscopy and Open Abdominal Surgery? Coronavirus disease 19 infection GeneXpert (Roche) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Basel Switzerland 2020-08-31 2021-02-28 052020, LapCoVIDSurg, NCT04444687 Phase Not Applicable Not yet recruiting 1 6 Months 20 Fabian Haak, Marco von Strauss und Torney 2020-06-26
Chloroquine Phosphate Prophylactic Use in Health Personnel Exposed to COVID-19 Patients Coronavirus disease 19 infection Plasmodin (chloroquine phosphate) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) ISSSTE Centro Medico Nacional 20 de Noviembre Mexico 2020-06-22 2020-11-30 01, NCT04443270 Phase 1 Clinical Not yet recruiting 1 5 Months 200 Alberto H De la Vega-Bravo, MD, Alejandro Alanis-Vega, MD, Carlos A Delgado-Quintana, MD, Eduardo Soei-Sarmiento, BsC, Fedra Irazoque-Palazuelos, MD, Fidel Cerda-Tellez, MD, Joel Vargas-Hernández, MD, Juan A Pineda-Juárez, PhD, Juan A Suárez-Cuenca, MD, PhD, Luis Montiel-López, MD, MSc, Maribel Santosbeña-Lagunes, MD, Maricela Escarela-Serrano, MD, María C Méndez-Vidrio, MD, Mireya Rodríguez-Martínez, MD, Paul Mondragón-Terán, PhD, Ricardo P Vázquez-Alvarado, MD, Sandra Muñoz-López, MD, MSc, Sofía L Alcaraz-Estrada, PhD 2020-06-25
Nitric Oxide Releasing Solution to Treat and Prevent Exacerbation of Mild COVID-19 Infection Coronavirus disease 19 infection nitric oxide-based antiviral formulation (nasal spray/nasopharyngeal flush, COVID-19), Sanotize Research and Development alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) SaNOtize Research and Development Corp Canada 2020-09-30 2021-07-31 COVID-IND-01, NCT04443868 Phase 2 Clinical Not yet recruiting 1 10 Months 300 Chris Miller, Ph.D., Jeremy Road, MD 2020-06-26
IMPReSSION: Improving Cardiovascular Risk Stratification Using T1 Mapping in General population Cardiovascular disease, Coronavirus disease 19 infection T1 mapping alone, T2 mapping alone, cardiovascular magnetic resonance alone, gadobutrol plus gadolinium Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Johann Wolfgang Goethe-Universitat Frankfurt am Main Johannes Gutenberg Universitat Mainz, Kerckhoff-Klinik GmbH, University Hospital Ulm Germany 2016-11-15 2026-11-15 IMPRESSION STUDY, IMPReSSION, NCT04444128 Phase Not Applicable Recruiting 3 120 Months 3000 Andreas Rolf, MD, Franziska Weis, Philip Wenzel, MD, Valentina O Puentmann, MD, PhD, Valentina Puentmann 2020-06-26
Insomnia After the COVID-19 Pandemic Anxiety disorder, Coronavirus disease 19 infection, Depression, Insomnia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Oslo Modum Bad Norway 2020-06-22 2020-07-13 NCT04443361, REK125510 (7) Phase Not Applicable Not yet recruiting 2 5000 Asle Hoffart, PhD, Omid Ebrahimi, Mr, Sverre Urnes Johnson, PhD 2020-06-26
A Phase I/II Study of COVID-19 DNA Vaccine (AG0301-COVID19) Coronavirus disease 19 infection AG-0301-COVID19 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) AnGes MG Inc Japan Agency for Medical Research and Development, Japan Medical Association Japan 2020-06-29 2021-07-31 AG0301-COVID19-JN-01, JapicCTI-205328, NCT04463472 Phase 1/Phase 2 Clinical Recruiting 1 13 Months 30 AnGes, Inc. Clinical Development 2020-07-10
SeroCoV-HUS: Seroprevalence of SARS-CoV-2 in Strasbourg University Hospital, Strasbourg, France (COVID-19) Coronavirus disease 19 infection COVID-19 BSS reference SW40005 diagnostic kit (Biosynex) alone, EDI Novel Coronavirus COVID-19 ELISA IgG kit (Epitope Diagnostics Inc) alone, ELISA alone, lateral flow assay-immuno-chromatographic test (LFA-ICT) alone, serological test alone, seroneutralization test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopitaux Universitaires de Strasbourg France 2020-04-17 2021-08-31 7782, NCT04441684, SeroCoV-HUS Phase Not Applicable Recruiting 1 16 Months 1800 Aleksandra NADAJ-PAKLEZA, MD, Catherine MUTTER, MD, David REY, MD PhD, Jean-Baptiste CHANSON, MD, Jérôme DE SEZE, MD PhD, Laurent KREMER, MD, Livia LANOTTE, MD, Maria GONZALEZ, MD PhD, Maria PARTISANI, MD, Marie MIELCAREK, MD, Marie-Aude SPITZ, MD, Marie-Céline FLEURY, MD, Nathalie PHILIPPI, MD, Nicolas COLLONGUES, MD, Nicolas LEFEBVRE, MD, Samira FAFI-KREMER, MD PhD, Yves HANSMANN, MD PhD 2020-06-25
Therapeutic Plasma Exchange for COVID-19-associated Hyperviscosity Coronavirus disease 19 infection, Vascular disease frozen plasma alone, therapeutic plasma exchange alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Emory University US 2020-07-31 2020-10-31 NCT04441996, STUDY00000949 Phase 4 Clinical Not yet recruiting 3 3 Months 20 Cheryl Maier, MD, PhD 2020-06-25
Convalescent Plasma Therapy on Critically-ill Novel Coronavirus (COVID-19) Patients Coronavirus disease 19 infection, Dyspnea, Viral pneumonia convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Alkarkh Health Directorate-Baghdad Iraq 2020-04-03 2020-06-01 CPT-COVID-19, NCT04441424 Phase 2 Clinical Completed 1 1 Month 49 Ahmed S Abdulamir, PhD 2020-06-27
Convalescent Plasma as a Possible Treatment for COVID-19 Coronavirus disease 19 infection convalescent plasma alone, convalescent plasma plus remdesivir COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Illinois US 2020-05-05 2021-05-05 2020-0441, NCT04442191 Phase 2 Clinical Recruiting 1 12 Months 50 Jesica A Herrick, MD, Jesica A Herrick, MD, MS, Jesica Herrick, Mahesh Patel, MD, Richard Novak, MD, Sally Campbell-Lee, MD 2020-06-26
A short-term follow-up study to assess the effect of SARS-CoV-2 total antibody assay in dialysis patients with Covid-19 Coronavirus disease 19 infection SARS-CoV-2 total antibody assay (Siemens Healthineers) alone Ascend Clinical, Stanford University School of Medicine US 2020-07-31 Phase Not Applicable Planned 1 30000 Shuchi Anand, MD 2020-06-25
Factors Associated With Adherence to Hygiene-related Behaviors and Viral Mitigation Protocols During the COVID-19 Pandemic Coronavirus disease 19 infection hygiene-related behavior alone, viral mitigation protocol alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Oslo Modum Bad Norway 2020-06-22 2020-07-13 NCT04442217, REK125510-11 Phase Not Applicable Not yet recruiting 2 4000 Asle Hoffart, PhD, Omid V. Ebrahimi, Double PhD Candidate, Sverre Urnes Johnson, PhD 2020-06-24
Assessment of Lung Inflammation With FDG PET/CT in COVID-19 Coronavirus disease 19 infection, Lung inflammation FDG alone, computerized tomography alone, positron emission tomography alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Princesse Grace Monaco 2020-03-27 2020-05-27 NCT04441489, PET-COVID Phase Not Applicable Completed 1 2 Months 13 2020-07-07
Spatial-temporal modelling, covid-19 Coronavirus disease 19 infection spatial-temporal modelling alone Universiti Kebangsaan Malaysia Malaysia 2020-07-01 2020-12-31 54919, NMRR-20-1178-54919 Phase Not Applicable Status not specified 1 6 Months Prof. Mohd Talib Latif 2020-06-25
COVID-19 Serosurvey Coronavirus disease 19 infection National Institutes of Health Malaysia Malaysia 2020-08-01 2020-10-30 55133, NMRR-20-1166-55133 Phase Not Applicable Not yet recruiting 1 2 Months Dr Chong Zhuo Lin, Mr. Mohd Hatta Bin Abdul Mutalip 2020-06-25
Impact survey Coronavirus disease 19 infection Sultanah Nur Zahirah Hospital Malaysia 2020-07-01 NMRR-20-1160-55260, NR 2020 55260 Phase Not Applicable Status not specified 1 DR nandinii a/p ramasenderan 2020-06-24
Tolerability, Safety, Pharmacokinetic Profile and Immunogenicity of a Recombinant Humanized Anti-SARS-CoV-2 Monoclonal Antibody (JS-016) for Injection in Chinese Health Subjects Coronavirus disease 19 infection JS-016 alone COVID19 Spike glycoprotein inhibitor Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Asian Ancestry Eli Lilly & Co, Shanghai Junshi Biosciences Co Ltd China, US 2020-06-05 2020-12-11 JS016-001-I, NCT04441918 Phase 1 Clinical Recruiting 2 6 Months 40 Jing Zhang, Wenhong Zhang 2020-07-07
A phase I clinical study of CDX-005 for the potential prevention of COVID-19 infection Coronavirus disease 19 infection CDX-005 alone Codagenix Inc Phase 1 Clinical Planned 0 2020-06-24
ALLOPRIME: Universal Anti-Viral Vaccine for Healthy Elderly Adults Coronavirus disease 19 infection AlloStim vaccine (Allo-priming, COVID-19), Immunovative Therapies alone Healthy volunteers accepted, Aged Adults (65-79 yrs), Elderly Adults (80 and over) Immunovative Therapies Ltd Mirror biologics, Inc US 2020-07-06 2021-12-31 ALLOPRIME, MBI-001-ALLOPRIME, NCT04441047 Phase 1/Phase 2 Clinical Not yet recruiting 1 17 Months 40 Azriel Hirschfield, MD, Kim Demonte, Thu Bui, MHA 2020-06-29
AfriCoVER: Characterising Transmission of SARS-CoV-2 in a Peri-urban Population in Mozambique Coronavirus disease 19 infection Healthy volunteers accepted Institute of Tropical Medicine, Belgium European and Developing Countries Clinical Trials Partnership, Institut de Recherche pour le Developpement (IRD), National Institute of Health, Mozambique, Universitair Medisch Centrum Utrecht Belgium, Mozambique 2020-07-15 2021-07-14 AFRICOVER, AfriCoVER, NCT04442165 Phase Not Applicable Not yet recruiting 2 12 Months 15393 Marc-Alain Widdowson, Dr, Natacha Herssens, MSc, Yven Van Herrewege 2020-06-25
The Impact of Information Sources on Mental Health During the COVID-19 Pandemic Anxiety disorder, Coronavirus disease 19 infection, Depression Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Oslo Modum Bad Norway 2020-06-22 2020-07-13 NCT04442360, REK125510-13 Phase Not Applicable Not yet recruiting 3 4000 Asle Hoffart, PhD, Ole Myklebust Amundsen, Cand.Psychol Student, Omid V. Ebrahimi, Double PhD Candidate, Omid V. Ebrahimi, PhD, Sverre Urnes Johnson, PhD 2020-06-24
A phase IIa, proof-of-concept study of FSD-201 for the treatment of COVID-19 infection Coronavirus disease 19 infection palmidrol + morphine (ultramicronized, severe chronic pain), FSD Pharma alone Cannabinoid CB2 receptor modulator, Opioid receptor mu agonist FSD Pharma Inc Phase 2a Clinical Planned 0 2020-06-23
Efficacy and Safety of Nitazoxanide 600 mg to Treat Mild Ambulatory COVID-19 Patients Coronavirus disease 19 infection, Viral respiratory tract infection Standard care alone, nitazoxanide (Viranitta) alone Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Azidus Brasil Farmoquimica SA Brazil 2020-07-31 2020-09-30 NCT04441398, NITFQM0720OR Phase 2/Phase 3 Clinical Not yet recruiting 1 2 Months 300 Edimilson Migowski, MD, Luciana Ferrara, Thiago Wendel, MD 2020-06-24
FOUND: Ancillary Study to Smile Protocol NCT03654105 Coronavirus disease 19 infection, Viral pneumonia Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Fondazione IRCCS Istituto Nazionale Tumori Universita degli Studi di Milano, Universita' Degli Studi Di Parma, University of Milano-Bicocca Italy 2019-07-23 2021-07-31 FOUND, INT 49/20, NCT04441814 Phase Not Applicable Recruiting 3 24 Months 960 Ugo Pastorino, MD 2020-06-24
Parental Stress After the Covid-19 Pandemic Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Oslo Modum Bad Norway 2020-06-22 2020-07-13 NCT04442308, REK125510 (6) Phase Not Applicable Not yet recruiting 4 1440 Asle Hoffart, PhD, Miriam S Johnson, PhD, Nora Paulsen Skjerdingstad, Omid Ebrahimi, Sverre Urnes Johnson, Sverre Urnes Johnson, PhD 2020-06-25
ILIAD-7-US-I: InterLeukin-7 to Improve Clinical Outcomes in Lymphopenic Patients With COVID-19 Infection Coronavirus disease 19 infection, Hypoxia, Lymphocytopenia, Respiratory failure CYT-107 alone IL-7 receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Revimmune Inc Amarex Clinical Research, Washington University in St Louis US 2020-06-30 2020-12-31 ILIAD-7 COVID US INFECTIOUS, ILIAD-7-US-I, NCT04442178 Phase 2 Clinical Not yet recruiting 1 6 Months 48 Frederique Berbille, MHSc, Michel Morre, DVM, Richard Hotchkiss, MD PhD 2020-07-01
PRIORITISE: Prognostication of Oxygen Requirement in Non-severe SARS-CoV-2 Infection Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Medecins Sans Frontieres, University of Oxford Foundation for Innovative New Diagnostics, International Centre For Diarrhoeal Disease Research, Bangladesh, The Mahidol Oxford Tropical Medicine Research Unit Bangladesh 2020-08-01 2021-03-01 0000, MSF0001, NCT04441372, PRIORITISE, PRIORITY Phase Not Applicable Not yet recruiting 1 7 Months 1200 Arjun Chandna, MD, Mikhael Yosia, MD, Mohammad Shomik, MD, Sakib Burza, PhD 2020-07-03
FamilyPEDCOVID: Study of Seroprevalence of Anti-SARS-CoV2 Among Children of Hospital Workers in AP-HP Coronavirus disease 19 infection serology test alone Healthy volunteers accepted Assistance Publique Hopitaux de Paris France 2020-06-30 2020-09-30 2020-A01480-39, APHP200627, FamilyPEDCOVID, NCT04442087 Phase Not Applicable Not yet recruiting 1 3 Months 400 Flore ROZENBERG, MD, PhD, Jean-Marc TRELUYER, MD, PhD, Jean-Marc Treluyer, MD, PhD, Michaela SEMERARO, MD, Solen KERNEIS, MD, Valérie JOLAINE, Master 2020-06-25
Predictors and Mechanisms of Depression and Anxiety During the COVID-19 Pandemic Anxiety disorder, Coronavirus disease 19 infection, Depression Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Oslo Modum Bad Norway 2020-06-22 2020-07-13 NCT04442204, REK125510-10 Phase Not Applicable Not yet recruiting 2 4000 Asle Hoffart, PhD, Omid Ebrahimi, Double PhD Candidate, Omid V. Ebrahimi, Double PhD Candidate, Sverre Urnes Johnson, PhD 2020-06-25
PsyCOVID: Ethical and Psychological Support for Health Care Professions in Intensive Care Units in the COVID-19 Pandemic Context: Adequacy With Needs and Psychological Impact Crisis and Post-crisis Coronavirus disease 19 infection, Psychiatric disorder Limesurvey platform alone, psychological interview alone, sociological interview alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire Dijon France 2020-04-21 2020-11-30 NCT04441476, PsyCOVID, QUENOT SERI 2020 Phase Not Applicable No longer recruiting 1 7 Months 3000 2020-06-25
PTSD Symptoms Among Health Workers and Public Service Providers After the COVID-19 Outbreak: A 3 Month, Follow-up Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Oslo Modum Bad Norway 2020-06-22 2020-07-13 NCT04442243, REK125510 (4) Phase Not Applicable Not yet recruiting 2 889 Asle Hoffart, PhD, Omid Ebrahimi, Omid Ebrahimi, Mr, Sverre Urnes Johnson, Sverre Urnes Johnson, PhD 2020-06-25
MARACOVID: Study to Evaluate the Efficacy and Safety of Maraviroc in SARS-CoV-2 Infection (COVID-19) Coronavirus disease 19 infection, Respiratory distress syndrome Standard care therapy alone, maraviroc alone CCR5 chemokine antagonist, CD4 agonist, HIV-1 gp120 protein inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Universitario Infanta Leonor Hospital Clinic of Barcelona, ViiV Healthcare Ltd Spain 2020-06-26 2020-12-20 2020-002011-21, MARACOVID, MARACOVID, NCT04441385 Phase 2 Clinical Recruiting 2 5 Months 200 Berta Torres, PhD, MD, Felipe García, PhD, MD, Guillermo Cuevas, MD, Jesus Troya, MD, Montserrat Laguno, PhD, MD, Pablo Ryan, MD, Rosa María Muñoz, Victor Domínguez, MD, Víctor Domínguez, MD, Álex Soriano, PhD, MD 2020-07-10
COVID_OMICS: Identification of Predictors for the Evolution of COVID-19 Related Pneumonia by Transcriptomic and Seroproteomic Cardiovascular injury, Coronavirus disease 19 infection, Interstitial lung disease, Viral pneumonia blood sampling alone, chest x-ray alone, computed tomography alone, echocardiography alone, genome analysis alone, seroproteomic analysis alone, transcriptional analysis alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) IRCCS Policlinico San Donato Italy 2020-03-30 2020-12-31 COVID19_OMICS, COVID_OMICS, NCT04441502 Phase Not Applicable Recruiting 1 9 Months 240 Ekaterina Baryshnikova, PhD, Fabio Martelli, PhD, Marco Ranucci, MD, Marco Ranucci, MD FESC, Massimiliano M Corsi Romanelli, MD PhD, Rosanna Cardani, PhD 2020-06-25
NasoVAX in Patients With Early Coronavirus Infectious Disease 2019 (COVID-19) Coronavirus disease 19 infection NasoVAX alone Hemagglutinin modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Altimmune Inc 2020-06-30 2020-12-31 ALT-601-201, NCT04442230 Phase 2 Clinical Not yet recruiting 0 6 Months 96 Christine Orlando, Staci Steele 2020-06-25
Evaluation of a COVID-19 antibody test: What is the performance of the Panbio COVID-19 IgG/IgM rapid test device in fingerstick blood, venous whole blood, serum and plasma in adult participants? Coronavirus disease 19 infection Panbio alone Abbott Laboratories Ltd UK 2020-04-06 2020-07-03 CLDG-0503, IRAS 283040, ISRCTN60400862 Phase Not Applicable No longer recruiting 2 2 Months Prof T.Kennedy 2020-06-29
Parental Burnout During the COVID-19 Pandemic: Risk Factors and Predictors Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Oslo Modum Bad Norway 2020-06-22 2020-07-13 NCT04442386, REK125510-15 Phase Not Applicable Not yet recruiting 2 1500 Asle Hoffart, PhD, Miriam Sinkerud Johnson, PhD, Nora Paulsen Skjerdingstad, Cand.psychol. stud, Omid V. Ebrahimi, Double PhD Candidate, Sverre Urnes Johnson, PhD 2020-06-24
DIAMONDS: DIAMONDS-SEARCH study: Designing new tests that can diagnose the causes of fever, including COVID-19 Coronavirus disease 19 infection Personalised Molecular Signature Diagnosis alone Imperial College London Germany, Switzerland, Greece, Netherlands, Austria, UK, Gambia, Taiwan, Nepal, Latvia, France, Slovenia, Spain, Italy 2020-01-01 2025-05-30 20SM5903, IRAS 278651, CPMS 45537, DIAMONDS, ISRCTN12394803 Phase Not Applicable Recruiting 35 64 Months 5000 Dr Federico Martinón-Torres, Prof Levin 2020-06-24
COV-IMMUNO: Immunization With IMM-101 Versus Observation for Prevention of Respiratory and Severe COVID-19 Related Infections in Cancer Patients at Increased Risk of Exposure Cancer, Coronavirus disease 19 infection, Lymphoma, Multiple myeloma, Respiratory tract infection, Solid tumor IMM-101 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Canadian Cancer Trials Group ATGen Canada Inc, BioCanRx, Canadian Cancer Society, Canadian Centre for Applied Research in Cancer Control, Immodulon Therapeutics Ltd, Ontario Institute for Cancer Research 2020-07-01 2021-03-31 COV-IMMUNO, IC8, NCT04442048 Phase 3 Clinical Not yet recruiting 0 9 Months 1500 Auer, Chris O'Callaghan, Rebecca A Auer 2020-06-30
Difficulties in Emotion-regulation and Interpersonal Problems During and After the COVID-19 Pandemic Anxiety disorder, Coronavirus disease 19 infection, Depression Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Oslo Modum Bad Norway 2020-06-22 2020-07-13 NCT04442282, REK125510 (5) Phase Not Applicable Not yet recruiting 2 5041 Asle Hoffart, PhD, Jon Monsen, PhD, Ole Andrè Solbakken, PhD, Omid Ebrahimi, Mr, Sverre Urnes Johnson, PhD 2020-06-24
A trial to evaluate ciclesonide for the treatment of patients with covid-19 Coronavirus disease 19 infection ciclesonide (nasal/aerosol formulation), Covis/AstraZeneca alone University at Buffalo US 2020-06-18 Phase 3 Clinical Recruiting 1 400 2020-06-23
CoVid3S: Caregiver Serological Monitoring Extended Secondarily to Patients With the SARS-CoV-2 Coronavirus Coronavirus disease 19 infection Healthy volunteers accepted Hospices Civils De Lyon France 2020-07-31 2022-01-31 69HCL20_0395, CoVid3S, NCT04441710 Phase Not Applicable Not yet recruiting 4 18 Months 2500 Antonin BAL, MD, Bruno POZZETTO, MD, François GUEYFFIER, MD, Julien LUPO, MD, Marine ALEXANDRE, Pascal FASCIA, MD 2020-06-24
NOXCOVID-1: A Phase I dose-escalation and dose-expansion study to evaluate the safety and proof-of- principle endpoints (biomarker and clinical responses)in SARS-CoV-2 infected patients Coronavirus disease 19 infection, Respiratory insufficiency, Septic shock idronoxil (suppository, late-stage prostate cancer/soft tissue sarcoma/cancers/COVID-19-associated diseases), Noxopharm alone CASP8-FADD-like regulator inhibitor, Ecto NOX disulfide thiol exchanger 2 inhibitor, Sphingosine kinase inhibitor, Sphingosine-1-phosphate receptor-1 antagonist, Stimulator of interferon genes protein stimulator, Topoisomerase inhibitor, X-linked inhibitor of apoptosis protein inhibitor Noxopharm Ltd Moldova, Republic of, Ukraine NOXCOVID-1 Phase 1 Clinical Planned 2 40 2020-06-29