Last updated: Jul 21, 2020 - 02:00 BST
| The Efficacy and Safety of Pyramax in Mild-to-Moderate COVID-19 Patients |
Coronavirus disease 19 infection |
pyronaridine + artesunate (oral), Medicines for Malaria Venture/Shin Poong/WHO alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shin Poong Pharmaceutical Co Ltd |
|
South Korea |
2020-07-31 |
2021-02-28 |
NCT04475107, SP-PA-COV-201 |
Phase 2 Clinical |
Recruiting |
0 |
7 Months |
76 |
Jandee Kim |
2020-07-20 |
| Role of immune boosting kit in covid disease |
Coronavirus disease 19 infection |
Variable regimens including anu taila , chyawanprash , chyawanprash avaleha , sanshamani vati |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
All India Institute of Ayurveda |
|
India |
2020-07-28 |
|
CTRI/2020/07/026670 |
Phase Not Applicable |
Not yet recruiting |
0 |
|
500 |
Dr SISIR KUMAR MANDAL |
2020-07-20 |
| What are the clinical effects in newborns born to mothers exposed to COVID-19 viral infection |
Coronavirus disease 19 infection |
|
|
Newborn Infants (up to 5 months) |
Chengalpattu Medical College |
|
India |
2020-07-30 |
|
CTRI/2020/07/026678 |
Phase Not Applicable |
Not yet recruiting |
0 |
|
200 |
Dr M Anitha |
2020-07-20 |
| Use of a Live Attenuated Vaccine as an Immune-based Preventive Against COVID-19-associated Sepsis |
Coronavirus disease 19 infection, Lung inflammation, Sepsis |
M-M-R II alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Louisiana State University Health Sciences Center New Orleans |
Parsemus Foundation |
US |
2020-08-17 |
2021-12-01 |
NCT04475081, PF-1214 |
Phase 3 Clinical |
Not yet recruiting |
0 |
15 Months |
60 |
Mary Meyaski, RN, Paul L Fidel, PhD |
2020-07-20 |
| Efficacy of Ayurveda treatment Protocol with Tulsimmune Tablet in Covid 19 |
Coronavirus disease 19 infection |
Ayurveda spice mix tablet (Tulsimmune) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Suraj Ayurveda Clinic and Research center |
H.J. Doshi Ghatkopar Hindusabha Hospital |
India |
2020-07-27 |
|
CTRI/2020/07/026675 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
0 |
|
76 |
Dr Akshaya Wagh Dr Pratika Kambale, Dr Ghanashyam Marda |
2020-07-20 |
| Ozone Therapy for Covid-19 patients |
Coronavirus disease 19 infection, Viral pneumonia |
ozone therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Neurogen Brain and Spine Institute |
Bisleri International Pvt. Ltd. |
India |
2020-07-27 |
|
CTRI/2020/07/026671 |
Phase Not Applicable |
Not yet recruiting |
0 |
|
10 |
Dr Alok Sharma, Dr Mili Arpan Shah |
2020-07-20 |
| Mental health affected by COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Tata Memorial Hospital |
|
India |
2020-07-28 |
|
CTRI/2020/07/026672 |
Phase Not Applicable |
Not yet recruiting |
0 |
|
2000 |
Arjun Singh, Pankaj Chaturvedi |
2020-07-20 |
| Effect of Ayurveda Spice Mix Tablet for the Prevention of COVID-19 infection in people exposed to Covid 19 and in high risk patients |
Coronavirus disease 19 infection |
Ayurveda Spice Mix alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Suraj Bio Herbal Pvt ltd |
Ashtang Ayurveda Mahavidyalaya |
India |
2020-07-27 |
|
CTRI/2020/07/026674 |
Phase 1 Clinical |
Not yet recruiting |
0 |
|
130 |
Dr Ghanashyam Marda, Dr Manoj Chaudhari |
2020-07-20 |
| SARS CoV2 pneumonia NIVS: Management of acute respiratory failure due to SARS CoV2 with non-invasive ventilatory support |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Azienda Sanitaria n. 4 Chiavarese, General hospital of sestri levante |
|
Italy, Spain |
2020-03-15 |
2020-05-25 |
ChiCTR2000034784, SARS CoV2 pneumonia NIVS |
Phase 4 Clinical |
Completed |
0 |
2 Months |
104 |
Nicolini Antonello, Russo Giuseppe |
2020-07-20 |
| Siddha formulations for the prevention of COVID-19 infection |
Coronavirus disease 19 infection |
Siddha formulation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Ministry of Ayush |
|
India |
2020-08-05 |
|
CTRI/2020/07/026673 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
60 |
Dr C Savariraj Sahayam, Dr G Karthikayan MBBS MS |
2020-07-20 |
| Can the Electronic Nose Smell COVID-19 Antibodies? |
Coronavirus disease 19 infection |
Aeonose alone, breath test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Maastricht University Medical Center |
|
Netherlands |
2020-04-06 |
2020-07-01 |
ENOSECOVIDANTIBODIES, NCT04475575 |
Phase Not Applicable |
Completed |
1 |
2 Months |
222 |
Nicole Bouvy |
2020-07-20 |
| CRAFTftiugr: The Effects of Mindfulness-based Training in Undergraduate Students of Translation and Interpreting |
Acute stress disorder, Anxiety disorder, Cognitive disorder, Coronavirus disease 19 infection |
The CRAFT program (adapted due to COVID-19) alone, The MBSR program (adapted due to COVID-19) alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Granada |
|
Spain |
2019-10-23 |
2020-10-31 |
CRAFTftiugr, NCT04392869, PIBPD 431 (PPFID 2018-2020) |
Phase Not Applicable |
No longer recruiting |
1 |
12 Months |
75 |
|
2020-07-20 |
| A real-time trial to evaluate the technology to screen Coronavirus disease 19 infection |
Coronavirus disease 19 infection |
advanced algorithms alone, artificial intelligence alone, thermal and visible-light cameras alone |
|
|
Foresight Autonomous Holdings Ltd |
|
Israel |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
|
|
2020-07-20 |
| PSICOcs: Online Survey on Psychological Impact of COVID-19 Epidemic on School-age Children |
Coronavirus disease 19 infection, Psychiatric disorder |
|
|
Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Hospices Civils De Lyon |
|
France |
2020-06-10 |
2020-12-31 |
NCT04475484, PSICOCS_2020, PSICOcs |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
30000 |
Pauline Espi, Pierre Fourneret, Pierre Pierre Fourneret |
2020-07-20 |
| Postural Recruitment Maneuver in Patients With Acute Respiratory Distress Syndrome Due to COVID-19 Infection |
Coronavirus disease 19 infection, Respiratory distress syndrome |
opioids therapy alone, postural recruitment maneuver alone, sedatives therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Nacional Edgardo Rebagliati Martins |
University of Piura |
Peru |
2020-07-31 |
2020-10-31 |
HNEDGARDOREBAGLIATIMARTINS, NCT04475068 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
12 |
Jorge A García, MD, Rollin Roldán, MD |
2020-07-20 |
| COVID-19; a report of three asymptomatic cases in a HEI in Sabah |
Coronavirus disease 19 infection |
|
|
|
Universiti Malaysia Sabah |
|
Malaysia |
2020-07-16 |
2020-08-07 |
55691, NMRR-20-1502-55691 |
Phase Not Applicable |
Status not specified |
1 |
|
|
Dr Syaza Putri Binti Zainudin |
2020-07-20 |
| QValidationKAPCOVID19: QValidationKAPCOVID19 |
Coronavirus disease 19 infection |
|
|
|
Hospital Tuanku Fauziah |
|
Malaysia |
2020-07-27 |
2021-07-27 |
55743, NMRR-20-1501-55743, QValidationKAPCOVID19 |
Phase Not Applicable |
Status not specified |
2 |
12 Months |
|
DR AMALINA BINTI ANUAR |
2020-07-20 |
| Co-Ab Study: COVID-19 Antibody Response |
Coronavirus disease 19 infection |
RT-PCR alone |
|
|
Hospital Sungai Buloh |
|
Malaysia |
2020-08-01 |
2021-08-01 |
Co-Ab Study, NMRR-20-1498-55694 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
250 |
Dr LIM KAH CHUAN, Dr Syarifah Nurul Ain Bt Syed Badaruddin |
2020-07-20 |
| Efficacy and Safety of Liposomal Lactoferrin in COVID-19 Patients With Mild-to-Moderate Disease and in COVID-19 Asymptomatic Patients |
Coronavirus disease 19 infection |
liposomal lactoferrin alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Rome Tor Vergata |
|
Italy |
2020-04-15 |
2020-07-02 |
4220, NCT04475120 |
Phase 2/Phase 3 Clinical |
Completed |
1 |
2 Months |
60 |
Elena Campione, Associate Professor |
2020-07-20 |
| Ordinary Clinical Waste Management and Covid-19 Clinical Waste |
Coronavirus disease 19 infection |
|
|
|
Universiti Malaysia Sabah |
|
Malaysia |
2020-07-20 |
2020-08-31 |
NMRR-20-1495-55515 |
Phase Not Applicable |
Status not specified |
1 |
1 Month |
|
Ms. Nurul Izzatul Fasihah Binti Roman Hatar |
2020-07-20 |
| The efficacy and safety of heparin in the treatment of novel coronavirus pneumonia (COVID-19): a prospective, randomized, controlled trial |
Coronavirus disease 19 infection, Viral pneumonia |
heparin alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Rui Jin Hospital |
Science and Technology Commission of Shanghai Municipality |
China |
2020-01-20 |
|
ChiCTR2000034796 |
Phase 0 Clinical |
Recruiting |
1 |
|
|
Enqiang Mao, Ma Li |
2020-07-20 |
| Safety and Efficacy of Maraviroc and/or Favipiravir versus Standard Therapy in Severe-non Critical COVID-19 Adults |
Coronavirus disease 19 infection |
standard therapy alone, Variable regimens including azithromycin , chloroquine , enoxaparin sodium , favipiravir , hydroxychloroquine , maraviroc |
CCR5 chemokine antagonist, CD4 agonist, HIV-1 gp120 protein inhibitor, Low molecular weight heparin, RNA polymerase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Hospital General de Mexico |
CCINSHAE. Secretaría de Salud. México, Centro de Investigación en. Enfermedades Infecciosas, Instituto Nacional de Ciencias Medicas y Nutricion |
Mexico |
2020-07-31 |
2021-01-31 |
DI/20/407/04/38, NCT04475991 |
Phase 2 Clinical |
Not yet recruiting |
1 |
6 Months |
100 |
Adolfo Pérez-García, PhD, Joselin Hernández-Ruiz, PhD, María Luisa Hernández-Medel, MD |
2020-07-20 |
| COVRESP: Safety and Effectiveness Assessment of the MakAir Artificial Ventilator |
Coronavirus disease 19 infection, Respiratory distress syndrome |
MakAir artificial ventilator alone, Mechanical ventilation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
CHU De Nantes |
|
|
2020-07-31 |
2020-10-31 |
COVRESP, NCT04475185, RC20_0173 |
Phase Not Applicable |
Not yet recruiting |
0 |
3 Months |
117 |
Antoine Roquilly, MD |
2020-07-20 |
| The therapeutic efficacy of Xuan-Fei Bai-Du decoction in the treatment of novel coronavirus pneumonia (COVID-19): a pilot randomized controlled trial |
Coronavirus disease 19 infection, Viral pneumonia |
Xuanfei Baidu Decoction alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Wuhan Hospital of Traditional Chinese Medicine |
|
China |
2020-01-28 |
2020-02-29 |
ChiCTR2000034795, ChiMCTR2000003500 |
Phase 0 Clinical |
No longer recruiting |
1 |
1 Month |
42 |
Wu-zhong Xiong |
2020-07-20 |
| Sancai granule improves lung and kidney function for patient with novel coronavirus pneumonia (COVID-19) in the recovery period: a randomized, parallel controlled trial |
Coronavirus disease 19 infection, Renal disease, Respiratory disorder, Viral pneumonia |
Sancai Granule alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Hubei province hospital of Traditional Chinese Medicine |
|
China |
2020-05-01 |
2021-04-30 |
ChiCTR2000034794, ChiMCTR2000003499 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
60 |
Ba Yuanming, Shen Yinfeng |
2020-07-20 |
| Telerehabilitation After Coronavirus |
Coronavirus disease 19 infection |
Aerobic Exercise Training alone, Respiratory Exercise Training alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
KTO Karatay University |
|
Turkey |
2020-06-19 |
2020-12-19 |
KARATAYU2, NCT04473898 |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
36 |
Bayram Sönmez Ünüvar, MsC, PT, Buse Kılınç, PT, Büşra Alkan, MsC, PT, RA, Büşra Alkan, MsC, PT,RA, Hasan Gerçek, PT, Kamil Yılmaz, Phd, PT, Melike Akdam, PT, RA, Osman Karaca, MsC,PT, Sinan Bağçacı, Dr, Özlem Akkoyun Sert, Phd, PT |
2020-07-20 |
| COVIDENZA: Enzalutamide Treatment in COVID-19 |
Coronavirus disease 19 infection |
enzalutamide alone, standard of care alone |
Androgen receptor antagonist, Cytochrome P450 3A4 stimulator, DNA binding protein inhibitor, Prostate specific antigen modulator, Translocation associated protein inhibitor |
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Västerbotten County Council, Sweden |
Astellas Pharma Europe Ltd, Göteborg University, Helsingborgs Hospital, Jonkoping County Hospital, Norrlands Universitetssjukhus, Sahlgrenska University Hospital, Skåne University Hospital, Sundsvall Hospital, Umea University, Umeå University Hospital, Uppsala University |
Sweden |
2020-07-15 |
2022-05-08 |
COVIDENZA, COVIDENZA, NCT04475601 |
Phase 2 Clinical |
Recruiting |
2 |
21 Months |
500 |
Anders Bjartell, Anders Bjartell, MD/Prof, Andreas Josefsson, Andreas Josefsson, MDPhD, Andreas Josefsson, MdPhD, Anna Henningsson Jonsson, MDPhD, Anna Nilsson, David Robinsson, MDPhD, Karin Welén, Assoc. Professor |
2020-07-20 |
| World Heart Federation (WHF) COVID-19 and Cardiovascular Disease Survey |
Cardiovascular disease, Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Public Health Foundation of India |
Centre for Chronic Disease Control, University of Cape Town, World Heart Federation, Geneva, Switzerland |
Bosnia and Herzegovina, Iran, Ghana, Argentina, Sudan, India |
2020-06-11 |
2021-12-30 |
NCT04475471, RA1413 |
Phase Not Applicable |
Recruiting |
8 |
18 Months |
5200 |
Ahmed Suliman, Alejo P. de la Hoz, Bishav Mohan, Bojan Stanetiic, DORAIRAJ PRABHAKARAN, MD, DM, Dorairaj Prabhakaran, Ezequiel J. Zaidel, Jose M. Aladio, KAREN SILWA, MD, PhD, KAVITA SINGH, PhD, Ladan Sadeghian, Lambert T. Appiah, Maia Matsudo, Nizal Sarrafzadegan, Pablo PEREL, MD, PhD, Ricardo P. de la Hoz, Sandra Swieszkowski, Sayed M. Hashemi |
2020-07-20 |
| A trial to evaluate opaganib for the treatment of patients with severe COVID-19 infection and pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
opaganib alone |
Dihydroceramide delta 4 desaturase inhibitor, Sphingosine kinase 2 inhibitor |
|
RedHill Biopharma Ltd |
|
Israel |
|
|
|
Phase 2 Clinical |
Not yet recruiting |
1 |
|
50 |
|
2020-07-20 |
| LICORNE: Lille COVID Research Network (Covid-19) |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Regional Universitaire de Lille |
|
France |
2020-07-31 |
2022-07-31 |
2020-A01514-35, 2020_54, LICORNE, NCT04475211 |
Phase Not Applicable |
Not yet recruiting |
1 |
24 Months |
1000 |
Marie-Charlotte CHOPIN, MD |
2020-07-20 |
| Trial comparing different doses of single-dose tocilizumab in adults with severe COVID-19 infection |
Coronavirus disease 19 infection |
tocilizumab (intravenous), Roche/Chugai alone |
IL-6 receptor antagonist, IL-6 receptor modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University College Dublin |
|
Ireland |
2020-06-25 |
|
2020-001767-86, COVIRL-002 |
Phase 2 Clinical |
Recruiting |
1 |
|
90 |
QRAM |
2020-07-20 |
| WHO-SOLIDARITY-GERMANY: An international randomized trial of additional treatments for COVID-19 in hospitalized patients who are all receiving the local standard of care |
Coronavirus disease 19 infection |
Variable regimens including Interferon beta-1a , lopinavir , remdesivir , ritonavir |
COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, Cytochrome P450 3A4 inhibitor, HIV protease inhibitor, HIV-1 protease inhibitor, RNA polymerase modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Landeszentrum Gesundheit Nordrhein-Westfalen |
German Federal Ministry of Education and Research |
Germany |
2020-06-29 |
|
2020-001549-38, WHO-SOLIDARITY-GERMANY |
Phase 3 Clinical |
Recruiting |
1 |
|
800 |
Institut für Pharmakologie |
2020-07-20 |
| [68Ga]Ga-DOTA-(RGD)2 PET/CT imaging of activated endothelium in lung parenchyma of COVID-19 patients |
Coronavirus disease 19 infection |
[68Ga]Ga-DOTA-E-(cRGDfK)2 alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Radboud University Medical Center Nijmegen |
|
Netherlands |
2020-05-20 |
|
2020-001325-31, NL73551.091.20 |
Phase 2 Clinical |
Recruiting |
1 |
|
10 |
Nuclear Medicine Research Office |
2020-07-20 |
| BADS-PTSD: Assessment of Mental Health in Healthcare Workers Exposed to COVID-19 Patients |
Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hamad Medical Corp |
|
Qatar |
2020-07-11 |
2021-06-30 |
BADS-PTSD, MRC-05-017, NCT04473118 |
Phase Not Applicable |
Recruiting |
1 |
11 Months |
25000 |
Ali Ait Hssain, Dr. Ali Ait Hssain, Sara Taleb |
2020-07-18 |
| QUICK: Lung Ultrasound for COVID-19 Initial Triage and Monitoring |
Coronavirus disease 19 infection |
computed tomography alone, thoracic lung ultrasound alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire de Toulouse |
|
France |
2020-05-27 |
2021-03-27 |
2020-A01445-34, NCT04474236, QUICK, RC31/20/0182 |
Phase Not Applicable |
Recruiting |
1 |
10 Months |
148 |
Benjamine SARTON, ph |
2020-07-20 |
| Ayurvedic formulations for the prevention of COVID-19 infection |
Coronavirus disease 19 infection |
Ayurvedic formulations alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Sastra University |
|
India |
2020-08-01 |
|
CTRI/2020/07/026530 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
200 |
Dr A Vinoth, Dr S Manickasubramaniam, Dr S Swaminathan |
2020-07-20 |
| Double-blind, randomized, controlled clinical trial to assess the efficacy of allogenic mesenchymal stromal cells in patients with acute respiratory distress syndrome due to COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
allogenic mesenchymal stromal cells alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cristina Avendaño Sola |
Hospital Puerta de Hierro Majadahonda |
Spain |
2020-06-15 |
|
2020-002193-27, COVID-AT |
Phase 2 Clinical |
Recruiting |
1 |
|
20 |
Concepcion Payares-Herrera |
2020-07-20 |
| ROLL OVER COVID: A Study of Lying Face Down to Help Improve Oxygen Levels of Adults Not Needing Ventilators in Intensive Care with COVID-19 |
Coronavirus disease 19 infection |
early prone positioning alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Royal Prince Alfred Hospital |
|
Australia |
2020-07-16 |
|
ACTRN12620000740998, ROLL OVER COVID |
Phase Not Applicable |
Not yet recruiting |
1 |
|
20 |
Dr Thomas Melhuish |
2020-07-20 |
| An Epidemiological Investigation on the Correct Wearing of Face Mask |
Coronavirus disease 19 infection, Respiratory tract infection |
FT-30 qualitative fitness test system (3M company) alone, Face mask wearing alone, breathing test alone, fitness test reagent spray test alone, hood wearing alone, sensitivity test alone, suitability test reagent spray test alone, visual inspection alone |
|
Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fuwai Yunnan Cardiovascular Hospital |
|
China |
2020-06-19 |
2020-08-31 |
2020-KZLXB-01, NCT04474028 |
Phase Not Applicable |
Recruiting |
8 |
2 Months |
5000 |
Bin Wen, Lin Duo, Pengxu Kong, Rundi Deng, Xiang-Bin Pan |
2020-07-18 |
| SENTAD-COVID: Study Evaluating the Safety and Efficacy of Autologous Non-Hematopoietic Peripheral Blood Stem Cells in COVID-19 |
Coronavirus disease 19 infection |
COVID-19 standard care alone, autologous non-hematopoietic peripheral blood stem cells alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Abu Dhabi Stem Cells Center |
|
United Arab Emirates |
2020-04-04 |
2020-07-14 |
CT.001.1.0.SENTAD-COVID, NCT04473170, SENTAD-COVID |
Phase 1/Phase 2 Clinical |
Completed |
1 |
3 Months |
146 |
Yendry Ventura Carmenate, M.D. |
2020-07-20 |
| Impact of COVID-19 on Marshallese Communities in the U.S |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Arkansas |
Patient Centered Outcome Research Institute |
US |
2020-07-20 |
2020-11-01 |
261131, NCT04474496 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
2000 |
Ralph Wilmoth, MPH, MPA |
2020-07-20 |
| Well-Being and Health-Related Quality of Life in Melanoma Patients During COVID-19 Pandemic |
Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression, Melanoma |
|
|
|
MD Anderson Cancer Center |
National Cancer Institute |
US |
2020-06-11 |
2021-07-01 |
2020-0470, NCI-2020-04587, NCT04474301, P30CA016672 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
1152 |
Lorenzo Cohen |
2020-07-20 |
| Optimizing Resource Allocation Via Prediction of Outcomes for COVID-19 |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Nottingham University Hospital |
East Midlands Academic Health Science Network |
UK |
2020-05-01 |
2020-07-31 |
20GA039, NCT04473105 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
500 |
Colin Crooks, MRCP, PhD, Timothy R Card, FRCP, PhD |
2020-07-20 |
| Epidemiological Assessment of SARS-CoV-2 (COVID-19) Prevalence in Minnesota |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Minnesota |
|
US |
2020-07-31 |
2022-01-31 |
NCT04473183, SURG-2020-28863 |
Phase Not Applicable |
Not yet recruiting |
1 |
18 Months |
3000 |
Luca Schifanella, MD, PhD |
2020-07-20 |
| IMPROVISE: Immune Profiling of COVID-19 patients Admitted to ICU |
Coronavirus disease 19 infection |
immune proteomics analysis alone, metabolomics analysis alone, serological test alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hamad Medical Corp |
Qatar University, Weill Cornell Medical College in Qatar |
Qatar |
2020-04-27 |
2022-06-30 |
IMPROVISE, MRC-05-007, NCT04473131 |
Phase Not Applicable |
Recruiting |
1 |
26 Months |
300 |
Ali Ait Hssain, Dr. Ali Ait Hssain, Sara Taleb |
2020-07-20 |
| Efficacy and Safety of Favipiravir in the Treatment of COVID-19 Patients > 15 Years of Age: A Multicenter, Observational Study |
Coronavirus disease 19 infection |
favipiravir alone |
RNA polymerase inhibitor |
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ministry of Health of Turkey |
Ankara City Hospital Bilkent, Ankara Training and Research Hospital, Ankara University, Ege University Hospital (Application and Research Center), Hacettepe University, Hacettepe University, School of Medicine, Istanbul Training and Research Hospital, Istanbul University, Istanbul University-Cerrahpasa, Kayseri City Hospital, Kocaeli Derince Training and Research Hospital, Prof. Dr. Cemil Tascıoglu City Hospital, Tepecik Training and Research Hospital, gulhane military medical academy, Ümraniye Training & Research Hospital |
Turkey |
2020-06-11 |
2020-09-30 |
COVID-19-PMS-FAV, NCT04474457 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
1000 |
Prof. Ates KARA, MD, Prof. Ateş KARA, MD |
2020-07-20 |
| COVID-19 Vaccine Trial in Healthy Volunteers |
Coronavirus disease 19 infection |
SARS-CoV-2 subunit vaccine (tobacco plant technology, COVID-19), Kentucky BioProcessing alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Kentucky BioProcessing Inc |
|
|
2020-07-20 |
2021-11-13 |
KBP-201, NCT04473690 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
0 |
15 Months |
180 |
Dennis Ruff, MD, Hugh Haydon, Kevin Cannon, MD, Oscar Guzman |
2020-07-20 |
| FUP-COVID: Follow-up of Critical COVID-19 Patients |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Uppsala University |
|
Sweden |
2020-06-25 |
2022-12-31 |
EPM-2020-02697, FUP-COVID, NCT04474249 |
Phase Not Applicable |
Recruiting |
1 |
30 Months |
300 |
Ewa Wallin, PhD., Ing-Marie Larsson, PhD., Michael Hultström, MD. PhD., Miklos Lipcsey, MD. PhD., Robert Frithiof, MD. PhD., Sten Rubertsson, MD. PhD. |
2020-07-20 |
| COVID-19 Convalescent Plasma Treatment in SARS-CoV-2 Infected Patients: Multicenter, Interventional Study |
Coronavirus disease 19 infection, Viral pneumonia |
COVID-19 convalescent plasma alone, hospital guideline based premedication therapy alone, steriod therapy alone, Variable regimens including COVID-19 convalescent plasma , acetaminophen , diphenhydramine |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ministry of Health in Kuwait |
|
Kuwait |
2020-05-21 |
2020-12-30 |
MOHKUWAIT, NCT04474340 |
Phase 1 Clinical |
Recruiting |
1 |
7 Months |
300 |
Abdullah Alsaedi, MD, Fatmah Alhuraish, MD, Mariam Ayed, Md, Najat Rouhaldeen, MD, Reem Ameen, PhD, Sondus AlSharida, MD, Sondus AlSharidah, Sondus AlSharidah, MD, Sundos Alsharida, Wasel Aladsani, MD |
2020-07-20 |
| Assessment of Lung Recruitablity of Acute Respiratory Distress Syndrome With SARS-CoV-2 Pneumonia by Electrical Impedance Tomography |
Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia |
electrical impedance tomography alone, opioid therapy alone, rocuronium alone, sedative therapy alone, ventilation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Osaka City University |
Hospital Edgardo Rebagliati Martins |
Japan |
2020-05-11 |
2020-08-31 |
ASPEIT, NCT04473300 |
Phase 2 Clinical |
Recruiting |
1 |
3 Months |
20 |
Takeshi Yoshida, M.D., Ph.D., Takeshi Yoshida, PhD |
2020-07-20 |
| A Study to evaluate the safety and efficacy of Eflornithine against the standard of care in human adult hospitalized COVID-19 patients |
Coronavirus disease 19 infection |
eflornithine alone |
Ornithine decarboxylase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
SRV Hospital |
|
India |
2020-07-20 |
|
CTRI/2020/07/026529 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
18 |
Dr Abhay Vispute Shantaram |
2020-07-20 |
| COVID-19 Preventive Measures Among Mansoura Nursing Students |
Coronavirus disease 19 infection |
|
|
|
Mansoura University |
|
Egypt |
2020-07-15 |
2020-12-31 |
NCT04473547, P.0203 |
Phase Not Applicable |
Recruiting |
1 |
5 Months |
215 |
Mohamed elsayed hamed elzeky, Wafaa G mohamed ali, professor, mohamed E elzeky, lecturer, mohamed elsayed elzeky, lecturer |
2020-07-20 |
| A clinical study to evaluate the efficacy of Arakoda for the potential treatment of COVID-19 |
Coronavirus disease 19 infection |
tafenoquine (oral tablet, malaria), 60° Pharmaceuticals/United States Army/Biocelect alone |
|
|
60° Pharmaceuticals LLC |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-07-17 |
| Development of early warning and rapid response system for patients with novel coronavirus pneumonia (COVID-19): a research protocol |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Beijing Tsinghua Chang Gung Hospital, Tsinghua University |
National Natural Science Foundation of China |
China |
2020-09-01 |
2021-08-31 |
ChiCTR2000034680 |
Phase Not Applicable |
Not yet recruiting |
2 |
12 Months |
200 |
Hua Zhou, Yuan Xu |
2020-07-20 |
| Siddha Treatment for COVID 19- a Pilot Study |
Coronavirus disease 19 infection |
Variable regimens including AAdathodai kudineer , bramanandha bairava mathirai , thaalisathi chooranam +thulasi chooranam +pavala parpam , thoothuvalai nei |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Dr Ambedkar arts college, Government Siddha Medical College |
|
India |
2020-07-27 |
|
CTRI/2020/07/026632 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
40 |
Dr J Nikil Niva, Dr R Sasirekha |
2020-07-20 |
| Uses of herbal combination by taking it in hot water in covid 19 positive patients |
Coronavirus disease 19 infection |
Variable regimens including Alpinia officinarum , Anethum sowa , Cuminum cyminum , Curcuma long , Justicia adhatoda , Melia Dubia , Mollugo serviana , Piper nigrum , Zingiber officinale |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kumarans fertility centre, Murugaa herbal research trust |
|
India |
2020-07-19 |
|
CTRI/2020/07/026631 |
Phase Not Applicable |
Not yet recruiting |
2 |
|
30 |
Dr Johnson Amalraj, Dr S Saravanan |
2020-07-20 |
| Spartan COVID-19 System: Evaluation of Clinical Sample Collection |
Coronavirus disease 19 infection |
Spartan COVID-19 System alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Spartan Bioscience Inc |
Humber River Hospital, The Ottawa Hospital |
Canada |
2020-06-28 |
2020-08-01 |
NCT04473248, VNV-00552 |
Phase Not Applicable |
Recruiting |
2 |
1 Month |
30 |
Derek So, MD, Jamie Spiegelman, MD, Tara Linseman, MSc |
2020-07-20 |
| Clinical trial of ACT 12 tablet and ACT 13 dry syrup in Covid 19 patients |
Coronavirus disease 19 infection |
standard of care alone, ACT 12 plus ACT 13 |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
GPLIFE HEALTHCARE PRIVATE LIMITED |
|
India |
2020-07-22 |
|
CTRI/2020/07/026630, MHC/CTH/20-21/002 |
Phase 2 Clinical |
Not yet recruiting |
2 |
|
60 |
Dr Patsute Sudhir Dadaram, Dr Pawan Kumar Singh, Dr Shridhar Pandya, VGVaidya |
2020-07-20 |
| Psycho-social Problems among COVID Infection Survivors |
Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression, Psychiatric disorder |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sanjay Gandhi Postgraduate Institute of Medical Sciences |
|
India |
2020-07-24 |
|
CTRI/2020/07/026612 |
Phase Not Applicable |
Not yet recruiting |
5 |
|
100 |
Dr Anshul Jain, Dr Himanshu Reddy, Dr Mallikarjun Gunjiganvi, Dr Rajeev Puri, Dr Vipin Dhama |
2020-07-20 |
| COVID-19 in Patients With Anosmia in Egypt |
Coronavirus disease 19 infection, Dysgeusia, Dysomia, Viral respiratory tract infection |
RT-PCR alone, standard management protocol alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ain Shams University |
|
Egypt |
2020-07-01 |
2020-10-30 |
FMASU P45A/2020, NCT04473157 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
50 |
Ossama I Mansour, MD |
2020-07-20 |
| GOTCHA: Glitazone Treatment for Coronavirus Hypoxia, a Safety and Tolerability, Open-label With Matching Cohort, Pilot Study |
Coronavirus disease 19 infection, Hypoxia |
pioglitazone alone, standard of care alone |
Insulin sensitizer, PPAR gamma agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Samaritan Health Services |
|
US |
2020-05-21 |
2021-06-01 |
GOTCHA, IRB20-042, NCT04473274 |
Phase 4 Clinical |
Recruiting |
1 |
12 Months |
20 |
Anthony Franklin, Brian Delmonaco, Brian Delmonaco, MD |
2020-07-17 |
| Safety and Efficacy of Melatonin in Outpatients Infected With COVID-19 (COVID-19) |
Coronavirus disease 19 infection |
melatonin (5-methoxy-N-acetyl tryptamine) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University at Buffalo |
|
US |
2020-08-11 |
2021-08-10 |
NCT04474483, UBMELCOVID19 |
Phase 2 Clinical |
Not yet recruiting |
1 |
12 Months |
30 |
Margarita Dubocovich, Ph.D., Margarita L Dubocovich, Ph.D., Sanjay Sethi, MD |
2020-07-20 |
| ROPRICo: ROPRICo |
Coronavirus disease 19 infection |
|
|
|
HOSPITAL SIBU |
|
Malaysia |
2020-08-01 |
2021-03-31 |
1.3, 55773, NMRR-20-1466-55773, ROPRICo |
Phase Not Applicable |
Not yet recruiting |
1 |
8 Months |
|
Dr Jeffrey Lee Soon Yit, Dr. Toh Teck Hock |
2020-07-20 |
| Burnout Among Critical Care Personnel in ICU During COVID-19 Pandemic |
Coronavirus disease 19 infection |
|
|
|
Hospital Raja Permaisuri Bainun |
|
Malaysia |
2020-07-31 |
2020-12-31 |
55681, BURN01, NMRR-20-1459-55681 |
Phase Not Applicable |
Not yet recruiting |
1 |
5 Months |
|
Dr Foong Kit Weng, Dr LEONG E LI |
2020-07-17 |
| COVID-19 Detection Tests in Different Body Fluids |
Coronavirus disease 19 infection |
qRT-PCR alone |
|
Healthy volunteers accepted, Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Nucleo De Pesquisa E Desenvolvimento De Medicamentos Da Universidade Federal Do Ceara |
Federal University of Ceara |
Brazil |
2020-07-31 |
2021-09-30 |
COVID FLUIDS, NCT04473352 |
Phase Not Applicable |
Not yet recruiting |
1 |
14 Months |
80 |
Eduardo P Miranda, PhD, Ricardo Reges, PhD |
2020-07-20 |
| Herbal formulation for immunity boosting during pandemic |
Coronavirus disease 19 infection |
Herbal Formulation alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
ayurved mahavidyalaya, nashik |
|
India |
2020-07-13 |
|
CTRI/2020/07/026528 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
500 |
Aparna Abhay Raut, Shailaja Prakash Chondikar |
2020-07-20 |
| Mental health among Malaysian healthcare workers in the midst of COVID-19 pandemic |
Coronavirus disease 19 infection |
|
|
|
JABATAN KESIHATAN NEGERI SELANGOR |
|
Malaysia |
2020-08-01 |
2021-07-31 |
55564, NMRR-20-1467-55564 |
Phase Not Applicable |
Status not specified |
1 |
12 Months |
|
DR MOHD FADHLI BIN MOHD FAUZI |
2020-07-20 |
| I-COVID-PK: Efficacy of Iodine Complex Against COVID-19 Patients |
Coronavirus disease 19 infection |
iodine complex capsule alone, iodine complex syrup alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Federal Postgraduate Medical Institute |
MTI Medical Private Limited |
Pakistan |
2020-07-14 |
2020-09-30 |
I-COVID-PK, NCT04473261, SZMC/IRB/INTERNAL/216/2020 |
Phase 1/Phase 2 Clinical |
Recruiting |
1 |
2 Months |
30 |
Moneeb Ashraf, MBBS, Muhammad Ahmad Imran, Muhammad Ahmad Imran, MBBS, Muhammad Ashraf, PhD, Shoaib Ashraf, PhD, Sohaib Ashraf, Sohaib Ashraf, MBBS, Uzma Nasim, FCPS |
2020-07-20 |
| Profile-Cov: Rapid Diagnostic Profiling of SARS-CoV-2 |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted |
Mekelle University |
Academic Medical Center, University of Amsterdam, Ethiopian Public Health Institute, Liverpool School of Tropical Medicine |
Ethiopia |
2020-07-20 |
2021-06-30 |
NCT04473365, Profile-Cov, RIA2020EF-2905 |
Phase Not Applicable |
Not yet recruiting |
1 |
11 Months |
186 |
Amanuel Haile, MD, Dawit Wolday, MD, PhD, Prof. Dawit Wolday |
2020-07-20 |
| COVID19 with Olfactory Impairment |
Coronavirus disease 19 infection, Hearing disorder |
|
|
|
Universiti Kebangsaan Malaysia |
|
Malaysia |
2020-07-13 |
2020-12-31 |
55312, NMRR-20-1448-55312 |
Phase Not Applicable |
Recruiting |
1 |
5 Months |
|
DR SALINA BINTI HUSAIN, OUI TING JIE |
2020-07-20 |
| A study to assess safety and efficy of Octagam in the treatment of Covid-19 |
Coronavirus disease 19 infection |
Octagam alone |
|
|
Octapharma AG |
|
Turkey |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
93 |
Figen Esen., Wolfgang Frenzel, |
2020-07-20 |
| SOVID: Surgical Outcomes in COVID-19 Patients (SOVID) |
Coronavirus disease 19 infection, Surgical procedure |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sanjay Gandhi Postgraduate Institute of Medical Sciences |
|
India |
2020-07-24 |
|
CTRI/2020/07/026611, SOVID |
Phase Not Applicable |
Not yet recruiting |
6 |
|
50 |
Dr Mallikarjun Gunjiganvi, Dr Neeraj Baronia, Dr Richa Jaiman, Dr Shabir Ahmad, Girish, Puneet |
2020-07-20 |
| A Multicenter Study Evaluating Clinical Course in Patients With COVID-19 and Its Relationship to Cytokine Storm |
Coronavirus disease 19 infection, Immune disorder, Sepsis |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hadassah Medical Organization |
Barzilai medical center, Chaim Sheba Medical Center |
Israel |
2020-06-28 |
2020-12-01 |
DM002, NCT04474067 |
Phase Not Applicable |
Recruiting |
1 |
5 Months |
300 |
Dror Mevorach, MD |
2020-07-20 |
| CPRC: The COVID-19 PUI Reality Check (CPRC) Study |
Coronavirus disease 19 infection |
immune assay alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Bassett Healthcare |
BioReference Laboratories |
US |
2020-07-15 |
2021-07-31 |
1613182, CPRC, NCT04474288 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
400 |
Catherine Gilmore, RN, Daniel Freilich, MD, Jennifer Victory, RN, daniel freilich, MD |
2020-07-20 |
| SPESELPIS: This Phase 1 clinical trial of NT-I7 is a multi-center, double-blind, randomized, placebo-controlled study that will evaluate the safety and efficacy of NT-I7 in adult patients with mild COVID-19 |
Coronavirus disease 19 infection |
efineptakin alfa alone |
IL-7 receptor agonist, Interleukin-7 ligand |
|
National Institute of Allergy and Infectious Diseases, National Institutes of Health, NeoImmuneTech Inc, University of Nebraska Medical Center |
National Institute of Allergy and Infectious Diseases, National Institutes of Health, University of Nebraska Medical Center |
|
|
|
SPESELPIS, SPESELPIS |
Phase 1 Clinical |
Not yet recruiting |
0 |
|
|
Andre Kalil, M.D., M.P.H, NgocDiep |
2020-07-17 |
| A clinical study to observe the effects of 8.4% sodium bicarbonate impregnated steam inhalation on Covid-19 infected patients |
Coronavirus disease 19 infection |
sodium bicarbonate alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Welcare Hospital |
Myself Health Check Ltd |
India |
2020-07-20 |
|
CTRI/2020/07/026535 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
60 |
Dr Bharat S Mody, Dr Kshitij B Mody |
2020-07-20 |
| A Phase I clinical trial of IDB-003 for potential treatment of SARS-CoV-2 infection |
Coronavirus disease 19 infection |
IDB-003 alone |
Angiotensin converting enzyme 2 inhibitor, COVID19 Spike glycoprotein modulator |
|
IDBiologics |
|
|
2020-09-30 |
|
|
Phase 1 Clinical |
Planned |
0 |
|
|
|
2020-07-17 |
| Physiotherapy as a Complimentary Treatment in Reducing Viral-Load, Complications, Death, Expedite Discharge and Improve Quality of Life, Exercise Endurance and Capacity in Stroke Survivors With CoViD-19: A Clinical-Controlled Study |
Coronavirus disease 19 infection, Stroke |
Rehabilitation exercise protocol alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universidad De Los Lagos |
|
Nigeria |
2020-07-13 |
2021-12-31 |
CMUL/HREC/06/20/742, NCT04471831 |
Phase Not Applicable |
Not yet recruiting |
1 |
17 Months |
30 |
Caleb AO Gbiri, PhD, Jibrin S Usman, MSc |
2020-07-20 |
| BEAT-CORONA: Building evidence to advance treatments for COVID-19 |
Coronavirus disease 19 infection |
|
|
|
Cambridge University Hospitals NHS Foundation Trust, University of Cambridge |
NIHR Cambridge Biomedical Research Centre |
UK |
2020-04-06 |
2025-04-30 |
2020-002016-48, BEAT-CORONA, CTU0306, IRAS 282317, ISRCTN89573163 |
Phase Not Applicable |
Recruiting |
1 |
60 Months |
|
Dr Brusby, Dr Thomas F Hiemstra |
2020-07-20 |
| Study of antiviral nutraceutical PICOVRID in COVID 19 patients |
Coronavirus disease 19 infection |
PICOVRID alone, Standard care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Indian Institute Of Technology Mumbai |
Government Medical College, Nagpur |
India |
2020-07-20 |
|
CTRI/2020/07/026534 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
70 |
Dr Rinti Banerjee, Dr Sushant Meshram |
2020-07-20 |
| Comparison to two different position to relieve difficulty in breathing in COVID- 19 patients |
Coronavirus disease 19 infection, Viral pneumonia |
Repeated Position Change alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
All India Institute of Medical Sciences |
|
India |
2020-07-14 |
|
CTRI/2020/07/026532 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
90 |
Dr Souvik Maitra |
2020-07-20 |
| Indian SARS-CoV2 Host Genetics Consortium |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Asian Ancestry |
MedGenome Labs Pvt Ltd |
Narayana Hrudayalaya LTD |
India |
2020-08-01 |
|
CTRI/2020/07/026531 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
3000 |
Dr Alben Sigamani |
2020-07-20 |
| REDMIC: A clinical trial to study the effects of two drugs methylprednisolone and dexamethasone in patients with severe COVID-19 |
Coronavirus disease 19 infection |
methylprednisolone alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Chettinad Hospital And Research Institute |
|
India |
2020-07-27 |
|
CTRI/2020/07/026608, REDMIC |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
40 |
Dr Ananthakumar P K, Prof V R Mohan Rao |
2020-07-20 |
| A phase II clinical trial of DPX-COVID-19 for the potential treatment of COVID-19 infection |
Coronavirus disease 19 infection |
DPX-COVID-19 alone |
|
|
IMV Inc |
|
|
2020-12-31 |
|
|
Phase 2 Clinical |
Planned |
0 |
|
|
|
2020-07-17 |
| MH Outcomes Selangor |
Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression |
|
|
|
JABATAN KESIHATAN NEGERI SELANGOR |
|
Malaysia |
2020-08-17 |
2021-03-17 |
55191, NMRR-20-1485-55191 |
Phase Not Applicable |
Status not specified |
1 |
7 Months |
|
Dr Rohaida Binti Ismail, Dr Siti Sara binti Yaacob |
2020-07-20 |
| NC4R |
Coronavirus disease 19 infection |
|
|
|
Selayang Hospital |
|
Malaysia |
2020-07-27 |
2020-09-30 |
55708, NMRR-20-1477-55708 |
Phase Not Applicable |
Status not specified |
17 |
2 Months |
|
Hafiz Git Kim Ann |
2020-07-20 |
| Psychosocial COVID |
Coronavirus disease 19 infection |
|
|
|
Hospital Sungai Buloh |
|
Malaysia |
2020-07-15 |
2020-10-31 |
55169, NMRR-20-1475-55169 |
Phase Not Applicable |
Status not specified |
1 |
3 Months |
|
Dr Lee Pei Yin |
2020-07-20 |
| CovConDa-Study: COVID-19 safe anesthetic gas measurement with the AnaConDaS system |
Coronavirus disease 19 infection |
AnaConDaS system alone, isoflurane alone, sevoflurane alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Katholisches Klinikum Bochum |
|
Germany |
2020-07-26 |
|
20-6938, CovConDa-Study, DRKS00022479 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
14 |
Mr. Dr. Martin Bellgardt |
2020-07-17 |
| Role of Herbal Immunomodulators in in Boosting the Immunity among healthcare workers assigned to COVID-19 wards |
Coronavirus disease 19 infection |
Guduchi plus Immusante |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Himalaya Drug Co |
|
India |
2020-07-24 |
|
CTRI/2020/07/026579, HDC/CP/PP/036/2020 Version 1.0 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
100 |
Dr C R Jayanthi, Dr Palaniyamma D, Dr Soorya Narayan H |
2020-07-20 |
| Sahadevi Choorna for COVID 19 |
Coronavirus disease 19 infection |
Sahadevi Powder alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Parul Institute of Ayurved |
|
India |
2020-07-20 |
|
CTRI/2020/07/026575 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
48 |
Dr Nandakishor P Umale |
2020-07-20 |
| To assess the seriousness in COVID-19 patients with the blood test report |
Coronavirus disease 19 infection |
|
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
All India Institute of Medical Sciences |
|
India |
2020-07-20 |
|
CTRI/2020/07/026574 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Yudhyavir Singh |
2020-07-20 |
| Pattern of ocular surface involvement in COVID-19 patients in Hassan, Karnataka |
Coronavirus disease 19 infection |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hassan institute of medical sciences |
|
India |
2020-07-21 |
|
CTRI/2020/07/026571 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
100 |
Dr Sandeep K |
2020-07-20 |
| Evaluation of atorvastatin tablet as an adjuvant treatment for patients with mild to moderate COVID-19 in Qaem Hospital, Mashhad |
Coronavirus disease 19 infection, Viral pneumonia |
atorvastatin alone |
HMG CoA reductase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Mashhad University of Medical Sciences |
|
Iran |
2020-07-21 |
|
IR.MUMS.REC.1399.221, IRCT20200408046990N3 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
40 |
Mohsen Tafaghodi, Sepideh Elyasi |
2020-07-20 |
| A phase III cinical trial of AZD-1222 for the treatment of Coronavirus disease 19 infection |
Coronavirus disease 19 infection |
AZD-1222 alone |
COVID19 Spike glycoprotein modulator |
|
AstraZeneca plc |
Biomedical Advanced Research and Development Authority (BARDA), US Department of Health and Human Services |
US |
|
|
|
Phase 3 Clinical |
Planned |
1 |
|
30000 |
|
2020-07-20 |
| Acupressure for COVID-19 Related Quality of Life and Stress |
Acute stress disorder, Coronavirus disease 19 infection |
Self-acupressure alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of California Los Angeles |
|
US |
2020-07-25 |
2021-02-25 |
20-000773, NCT04472559 |
Phase Not Applicable |
Not yet recruiting |
1 |
7 Months |
200 |
Kakit P. Hui, MD, Ryan Abbott, MD, PhD |
2020-07-20 |
| Locally Produced Cloth Face Mask and COVID-19 Like Illness Prevention |
Ageusia, Coronavirus disease 19 infection, Cough, Dysomia, Dyspnea, Fever, Respiratory disease |
Certified cloth face mask alone, Information on COVID-19 prevention alone |
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Bandim Health Project |
Engineers without Borders, Denmark, University of Southern Denmark |
Guinea-Bissau |
2020-07-31 |
2020-11-30 |
BHP MASK01, NCT04471766 |
Phase Not Applicable |
Not yet recruiting |
1 |
4 Months |
66000 |
Amabelia Rodrigues, PhD |
2020-07-20 |
| COVA: Testing the Efficacy and Safety of BIO101 for the Prevention of Respiratory Deterioration in COVID-19 Patients |
Coronavirus disease 19 infection, Respiratory disease, Respiratory distress syndrome, Viral pneumonia |
20‐hydroxyecdysone (oral, sarcopenia/sarcopenic obesity/Duchenne muscular dystrophy/ARDS associated with COVID-19), BIOPHYTIS alone |
Proto-oncogene Mas agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
BIOPHYTIS |
|
France, US, Belgium, UK |
2020-06-16 |
2021-09-30 |
2020-001498-63, BIO101-CL05, COVA, NCT04472728 |
Phase 2/Phase 3 Clinical |
Recruiting |
4 |
15 Months |
310 |
Capucine Morelot-Panzini, MD, Dr Muriel Lins, Mounia Chabane De Saint Aubin, Muriel Lins, MD, Shmuel Agus, MD, Waly Dioh, PhD |
2020-07-17 |
| Study of an Ayurveda regimen in COVID Positive patients |
Coronavirus disease 19 infection |
Dasamoolakadutrayadi Kashayam alone, Guluchyadi Kwatham alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Deenanath Mangeshkar Hospital and Research Center |
|
India |
2020-07-24 |
|
CTRI/2020/07/026602 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
72 |
Dr Pankaj Wanjarkhedkar |
2020-07-20 |
| A study to check effect of an Ayurvedic treatment on corona positive patients |
Coronavirus disease 19 infection |
conventional treatment alone, Variable regimens including Bilvadi , Surasadi Kadha , Vironil |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Aarti Foundation, Kutchhi Jain Foundation |
District Civil Hospital Beed |
India |
2020-07-21 |
|
CTRI/2020/07/026601 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
70 |
DrShivprasad Charkha |
2020-07-20 |
| An expansive subject study to evaluate the efficacy of AZD-1222 for the potential prevention of COVID-19 infection |
Coronavirus disease 19 infection |
AZD-1222 alone |
COVID19 Spike glycoprotein modulator |
|
AstraZeneca plc, IQVIA Holdings Inc |
|
US |
|
|
|
Phase Not Applicable |
Planned |
1 |
|
|
|
2020-07-17 |
| Expanded Access to Convalescent Plasma for Treatment of COVID-19 |
Coronavirus disease 19 infection, Dyspnea, Multiple organ failure, Respiratory failure, Septic shock |
convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hackensack Meridian Health |
|
US |
|
|
NCT04472572, PRO2020-0663 |
Phase Not Applicable |
Suspended |
1 |
|
|
Michele Donato |
2020-07-20 |
| Nelfinavir and Favipiravir Combination in Newly Diagnosed COVID19 Egyptian Patients |
Coronavirus disease 19 infection |
favipiravir plus nelfinavir |
HIV protease inhibitor, HIV-1 protease inhibitor, RNA polymerase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Tanta University |
|
Egypt |
2020-08-31 |
2020-12-31 |
NCT04471662, NELFINAVIR/FAVIPIRAVIR |
Phase 2 Clinical |
Not yet recruiting |
1 |
4 Months |
50 |
Nahla El-Ashmawy, PhD |
2020-07-20 |
| COLSTAT: Colchicine/Statins for the Prevention of COVID-19 Complications (COLSTAT) Trial |
Coronavirus disease 19 infection |
Standard of care alone, colchicine plus rosuvastatin |
HMG CoA reductase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Yale University |
|
US |
2020-08-01 |
2022-08-01 |
2000027950, COLSTAT, NCT04472611 |
Phase 3 Clinical |
Not yet recruiting |
1 |
24 Months |
824 |
Alexandra Lansky, MD, Marianne McCarthy, MBA |
2020-07-20 |
| RETURN: Repeated Employee Testing for Understanding the Recovery to Normal |
Coronavirus disease 19 infection |
ELISA alone, biological sampling alone, polymerase chain reaction alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cincinnati Children's Hospital Medical Center |
|
US |
2020-05-11 |
2023-12-31 |
NCT04472793, RETURN, RETURN |
Phase Not Applicable |
Recruiting |
1 |
43 Months |
200 |
Mary Allen Staat, MD, MPH, Maureen Carolin, Russell Ware, MD, PhD, Teresa Latham |
2020-07-20 |
| A randomized, contrlled clinical trial on adjuvant TCM herbal treatment to prevent deterioration and improve outcome of COVID-19 patients in Singapore |
Coronavirus disease 19 infection |
TCM herbal alone |
|
|
Singapore General Hospital Pte Ltd |
|
Singapore |
|
|
TCMC19-P2 |
Phase 3 Clinical |
Status not specified |
1 |
|
|
Dr Tan Thuan Tong, Jamie Chien Mei Fong |
2020-07-17 |
| SINZ-COVID-PK: Efficacy of Subcutaneous Ivermectin With or Without Zinc and Nigella Sativa in COVID-19 Patients |
Coronavirus disease 19 infection |
ivermectin (Montpellier) alone, standard care alone, Variable regimens including Nigella Sativa/Black Cumin extract , ivermectin (Montpellier) , zinc sulphate |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Federal Postgraduate Medical Institute |
|
Pakistan |
2020-07-14 |
2020-09-30 |
NCT04472585, SINZ-COVID-PK, SZMC/IRB/INTERNAL/215/2020 |
Phase 1/Phase 2 Clinical |
Recruiting |
1 |
2 Months |
40 |
Moneeb Ashraf, MBBS, Muhammad Ahmad Imran, Muhammad Ahmad Imran, MBBS, Muhammad Ashraf, PhD, Shoaib Ashraf, PhD, Sohaib Ashraf, Sohaib Ashraf, MBBS |
2020-07-19 |
| Covid-19: Hydroxychloroquine and Covid in RA Patients |
Coronavirus disease 19 infection |
hydroxychloroquine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tanta University |
|
Egypt |
2020-06-15 |
2020-09-30 |
002, Covid-19, NCT04471649 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
80 |
Asem Elfert, Prof, Mohammed Hassan Abu-Zaid, Mohammed Hassan Abu-Zaid, PhD, Samar A Tabra, PhD, Samar Tabra, PhD |
2020-07-18 |
| A Post Marketing Surveillance (PMS) study to monitor the efficacy and safety of FabiFlu in patients with COVID 19 |
Coronavirus disease 19 infection |
favipiravir alone |
RNA polymerase inhibitor |
|
Glenmark Pharmaceuticals Ltd |
|
|
|
|
|
Phase 4 Clinical |
Recruiting |
0 |
|
1000 |
|
2020-07-16 |
| A multicenter prospective study utilizing Daxor’s BVA-100 (Blood Volume Analyzer, “BVA”) technology in hospitalized COVID-19 patients |
Coronavirus disease 19 infection |
Daxor’s BVA-100 alone |
|
|
Daxor Corp |
|
US |
2020-07-15 |
|
|
Phase Not Applicable |
Recruiting |
1 |
|
|
|
2020-07-16 |
| Seroprevalence of Coronavirus Disease 2019 (COVID-19) Antibodies in a Vulnerable Neighbourhood, Buenos Aries Argentina |
Coronavirus disease 19 infection |
|
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Italiano de Buenos Aires |
Hospital de Niños R. Gutierrez de Buenos Aires, Salud Comunitaria Ministerio de Salud GCBA |
Argentina |
2020-06-10 |
2020-07-18 |
1831, NCT04472078 |
Phase Not Applicable |
No longer recruiting |
1 |
1 Month |
873 |
Alicia Mistchenko, MD PHD, Ana M Gomez Saldaño, MD MG, Andrea Gamarnik, PHD, Fernan Quiroz, MD MG, Julieta Salto, Lorena Luna, MG, Magdalena Wagner Manslau, Silvana Figar, MD MG, Vanina L Pagotto, MD MG |
2020-07-17 |
| MR SPOC: Telemedicine in Outpatient Covid-19 Patients |
Arterial hypertension, Atrial fibrillation, Coronary artery disease, Coronavirus disease 19 infection, Diabetes mellitus, Diastolic heart failure, Myocardial infarction, Nicotine dependence, Systolic heart failure |
Withings ScanWatch alone, medical hotline telemedicine care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Ludwig-Maximilians University of Munich |
German Centre for Cardiovascular Research, Referat für Gesundheit und Umwelt (RGU), Landeshauptstadt München |
Germany |
2020-08-31 |
2021-01-31 |
20-448, MR SPOC, NCT04471636 |
Phase Not Applicable |
Not yet recruiting |
1 |
5 Months |
600 |
Moritz F Sinner, MD, MPH, Moritz F. Sinner, Stefan Kääb, MD, PhD, Steffen Massberg, MD |
2020-07-20 |
| Frequency of Perforated Appendicitis in Times of COVID-19 |
Appendicitis, Coronavirus disease 19 infection |
appendectomy alone, cefotaxime plus metronidazole |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Tubingen |
|
Germany |
2020-03-16 |
2020-05-31 |
AZ: 324/2020BO2, NCT04472052 |
Phase Not Applicable |
Completed |
1 |
2 Months |
143 |
|
2020-07-18 |
| EPICOVID19: Italian Web-based Cross-sectional Survey |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Institute of Biomedical Technologies-National Research Council |
CNR Institute of Clinical Physiology, Institute of Neuroscience-National Research Council, Italian Society of Geriatrics and Gerontology, Italian Society of Infectious and Tropical Diseases, Universita degli Studi di Milano |
Italy |
2020-04-13 |
2020-08-31 |
EPICOVID19, EPICOVID19_2020, NCT04471701 |
Phase Not Applicable |
Recruiting |
1 |
4 Months |
200000 |
Federica Prinelli, PhD, Fulvio Adorni, MPH |
2020-07-17 |
| A clinical trial of 2X-121 for the tretment of Coronavirus disease 19 infection |
Coronavirus disease 19 infection |
2X-121 alone |
Poly ADP ribose polymerase 1 inhibitor, Poly ADP ribose polymerase 2 inhibitor, Tankyrase-1 inhibitor, Tankyrase-2 inhibitor |
|
National Institutes of Health, Oncology Venture A/S |
Northern Arizona University |
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-07-16 |
| A randomized, double-blind, placebo-controlled, investigator-sponsored study to evaluate the safety and efficacy of vadadustat for hypoxemia due to COVID-19, the disease caused by SARS-CoV-2 |
Coronavirus disease 19 infection, Hypoxia |
vadadustat alone |
HIF prolyl hydroxylase inhibitor, Hypoxia inducible factor inhibitor gene inhibitor, Hypoxia inducible factor-2 alpha modulator |
|
Akebia Therapeutics Inc, University of Texas Health Science Center Houston |
|
US |
2020-07-14 |
|
|
Phase 3 Clinical |
Recruiting |
1 |
|
300 |
Bentley J. Bobrow, Holger K. Eltzschig |
2020-07-16 |
| Systematic Assessment of SARS-CoV-2 Neurotropic Capacity in Modestly and Critically Ill Patients, and Patients Who Died From COVID-19 |
Coronavirus disease 19 infection |
CODEX fluorescent microscopy alone, CyTOF mass cytometry alone, OLINK Proximity Extension Assay alone, biological sampling alone, magnetic resonance imaging alone, multiplexed ion beam imaging alone, qPCR alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Basel |
University of Basel |
Switzerland |
2020-09-30 |
2022-12-31 |
2020-01503, CH20HUTTER, NCT04472013 |
Phase Not Applicable |
Not yet recruiting |
2 |
27 Months |
40 |
David Winkler, PD Dr. med., Gregor Hutter, Prof. Dr. med. |
2020-07-17 |
| A phase II/III trial to evaluate SARS-CoV-2 vaccine (VLP, COVID-19), Medicago for the prevention of Covid-19 |
Coronavirus disease 19 infection |
MT-2766 alone |
TLR-9 agonist |
|
Medicago Inc |
|
|
2020-10-31 |
|
|
Phase 2/Phase 3 Clinical |
Planned |
0 |
|
|
|
2020-07-17 |
| Study of Abatacept in the Treatment of Hospitalized COVID-19 Participants With Respiratory Compromise |
Coronavirus disease 19 infection, Respiratory disease |
abatacept alone, standard of care alone |
Cytotoxic T-lymphocyte protein-4 stimulator, T cell surface glycoprotein CD28 inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Bristol-Myers Squibb Co |
|
US |
2020-07-20 |
2021-01-14 |
IM101-873, NCT04472494, U1111-1250-4217 |
Phase 2 Clinical |
Not yet recruiting |
4 |
5 Months |
129 |
Bristol-Myers Squibb, Site 0001, Site 0002, Site 0003, Site 0004 |
2020-07-17 |
| A global study to assess safety and efficacy of itolizumab in patients with COVID-19 |
Coronavirus disease 19 infection |
itolizumab alone |
T-cell differentiation antigen CD6 inhibitor |
|
Equillium Inc |
|
US |
|
|
|
Phase Not Applicable |
Planned |
1 |
|
|
|
2020-07-16 |
| Lung ultrasound to predict invasive ventilation of patients with COVID-19 lung disease |
Coronavirus disease 19 infection |
lung ultrasound alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Gold Coast Hospital, Monash University |
|
Ireland, Canada, Australia, US |
2020-07-13 |
2021-12-31 |
ACTRN12620000734965, U1111-1254-7764 |
Phase Not Applicable |
Not yet recruiting |
10 |
17 Months |
1000 |
Dr Gabriel Bletcher, Dr Peter J Snelling |
2020-07-17 |
| Will treating the overwhelming patient response with medications affect COVID-19 mortality |
Coronavirus disease 19 infection |
losartan alone |
Angiotensin II AT-1 receptor antagonist, Angiotensin II receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
New South Wales Ministry of Health |
|
Australia |
2020-09-01 |
|
ACTRN12620000731998p, U1111-1252-6251 |
Phase 1 Clinical |
Not yet recruiting |
4 |
|
36 |
Prof Jennifer Martin |
2020-07-17 |
| Use of Anti-IL-17 in patients with Covid-19 associated pneumonia |
Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia |
secukinumab alone, standard treatment alone |
IL-17 antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fundaçao de Amparo a Pesquisa do Rio Grande do Sul, Ministry of Science and Technology, Brazil, NOVARTIS BIOCIENCIAS S.A. |
Conselho Nacional de Desenvolvimento Cientifico e Tecnologico - CNPq, Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, FAPEMIG, Hospital Risoleta Tolentino Neves |
Brazil |
2020-07-10 |
|
32224420.3.0000.0008, 4.100.115, A03746497663, Nº 11/2020, RBR-5vpyh4 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
50 |
GUSTAVO GOMES RESENDE |
2020-07-17 |
| MuSPAD: Multi-local and serial, cross-sectional, prevalence study on antibodies against SARS-CoV-2 (COVID-19) in Germany |
Coronavirus disease 19 infection |
serological test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Helmholtz Zentrum fur Infektionsforschung GmbH |
Bundesministerium fur Bildung und Forschung, Deutsche Forschungsgemeinschaft (DFG), German Federal Ministry of Education and Research, NaturWissenschaftliches Und Medizinisches Institut An Der Universitaet Tuebingen In Reutlingen |
Germany |
2020-07-01 |
|
9086_BO_S_2020, DRKS00022335, MuSPAD |
Phase Not Applicable |
Recruiting |
4 |
|
60000 |
Daniela Gornyk, Gérard Krause |
2020-07-17 |
| COVID-19 cohort Würzburg: Prospective collection of data and biomaterial of COVID-19 at the location Würzburg |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Würzburg |
|
Germany |
2020-05-15 |
|
89/20-sc, COVID-19 cohort Würzburg, DRKS00022402 |
Phase Not Applicable |
Recruiting |
1 |
|
400 |
*** *** |
2020-07-17 |
| COVID-19 IgG Antibodies in the Serum of Recovered Patients |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assiut University |
|
Egypt |
2020-08-01 |
2021-09-01 |
COV-PH2020, NCT04470414 |
Phase Not Applicable |
Not yet recruiting |
1 |
13 Months |
100 |
Mahmoud A. Abd El Aty, Prof., Mariam Amin, Mariam T. Amin |
2020-07-17 |
| Relation Between Lab Finding and COVID-19 Severity |
Coronavirus disease 19 infection |
CELL-DYN 3700 alone, Liver function test alone |
|
|
Assiut University |
|
Egypt |
2020-07-15 |
2020-12-01 |
NCT04470557, RLCS |
Phase Not Applicable |
Not yet recruiting |
1 |
4 Months |
100 |
Anwar M. Ali, Doctorate, Anwar Mohamed Ali, Esam_eldeen M. Abdalla, Doctorate, Ghydaa A. Shehata, Doctorate, Heba Abdellatif, Doctorate |
2020-07-16 |
| PULDAMCO: Pulmonary Damage after hospitalization for acute Covid‐19 (PULDAMCO), an exploratory, prospective, cohort study |
Coronavirus disease 19 infection |
CT angiography alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Radboud University Medical Center Nijmegen |
|
Netherlands |
2020-07-07 |
2021-07-29 |
2020-6637, NL8765, PULDAMCO |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
150 |
Bram van den Borst |
2020-07-19 |
| Impact on the OLAF Intervention to Prevent Post Traumatic Disorders During the Confinement |
Coronavirus disease 19 infection, Post traumatic stress disorder |
OLAF intervention alone, Phone call alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire de Toulouse |
|
France |
2020-06-12 |
2021-10-12 |
NCT04470869, RC31/20/0190 |
Phase Not Applicable |
Recruiting |
1 |
16 Months |
130 |
Guillaume Ducos, MD, Juliette SALLES, MD |
2020-07-20 |
| Changes in Cellular Immune Profile During COVID-19 Infection |
Coronavirus disease 19 infection |
Leukapheresis alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Seraph Research Institute |
Scripps Research Institute |
US |
2020-04-15 |
2020-12-31 |
NCT04470999, SRPH-CVD-01 |
Phase Not Applicable |
Recruiting |
0 |
8 Months |
25 |
Gregory T Howell, BA Psy, Kristen Terry, Serhat Gumrukcu, MD PhD |
2020-07-16 |
| COVID-19 Infection at Samusocial in Paris: Descriptive and Serological Survey |
Coronavirus disease 19 infection |
bood test alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
INSERM |
Assistance Publique Hopitaux de Paris, Samusocial de Paris |
France |
2020-07-31 |
2020-11-30 |
C20-50, NCT04470648 |
Phase Not Applicable |
Not yet recruiting |
3 |
4 Months |
220 |
Anne Rachline, MD, Armelle Pasquet, MD, Yazdan Yazdanpanah, MD PHD |
2020-07-16 |
| The Prevalence of persistent viral shedding and antibody levels among recovered COVID-19 patients of the hospitals and Public Health Centers under Bangkok Metropolitan Administration |
Coronavirus disease 19 infection |
|
|
|
Chulalongkorn University |
|
Thailand |
2020-06-10 |
|
TCTR20200708001 |
Phase Not Applicable |
Recruiting |
1 |
|
239 |
Chintana Chirathaworn, Pijaya Nagavajara, Yong Poovarawan |
2020-07-16 |
| Serosurvey for antibodies against SARS-CoV-2 in Pune city |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
IISER Pune |
|
India |
2020-07-20 |
|
CTRI/2020/07/026509 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1520 |
Aarti Nagarkar, Aurnab Ghose, L S Shashidhara |
2020-07-16 |
| Knowledge, attitude and practices of Filipino residents and healthcare providers regarding COVID-19 pandemic in the Philippines: Framework for developing effective health programs and strategies |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted |
Ehime University, University of the East Ramon Magsaysay Memorial Medical Center, Inc, University of the Philippines Manila |
Japan Society for the Promotion of Science (JSPS), Sumitomo Electrical Industries Ltd |
Japan, Philippines, Indonesia |
2020-07-13 |
2021-07-13 |
PHRR200713-002756 |
Phase Not Applicable |
Recruiting |
3 |
12 Months |
|
Angelica V. Tomas, MD, Camille Erika S. Chan, MD, DR. KOZO WATANABE, Ferdinand S. de Guzman, Milagros B. Rabe, Minette Claire O. Rosario, MD, VON RALPH DANE MARQUEZ HERBUELA |
2020-07-17 |
| Logistical concerns faced by OB Frontliners during the COVID-19 pandemic in a COVID referral hospital in the Philippines |
Coronavirus disease 19 infection |
|
|
|
Philippine General Hospital |
|
Philippines |
2020-07-01 |
2020-09-01 |
PHRR200708-002744 |
Phase Not Applicable |
Not yet recruiting |
1 |
2 Months |
|
Bernadette Alcazaren |
2020-07-15 |
| Genome Sequencing of COVID-19 virus |
Coronavirus disease 19 infection |
Genome Sequencing alone |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
B. J. Medical College, Pune, Savitribai Phule Pune University |
|
India |
2020-07-20 |
|
CTRI/2020/07/026508 |
Phase Not Applicable |
Not yet recruiting |
2 |
|
100 |
Dr Rajesh Karyakarte, Dr Yogesh Shouche Scientist G |
2020-07-16 |
| Evaluation of the performance of India Health Foundation’s (IHF’s) RT PCR kit for detection of COVID-19 virus (SARS-CoV-2) antigens |
Coronavirus disease 19 infection |
RT PCR assay alone, RT PCR kit alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Capital Health Services India Pvt Ltd |
|
India |
2020-07-20 |
|
CTRI/2020/07/026499 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1000 |
Dr R Arunkumar |
2020-07-16 |
| A Phase Ib Trial to Evaluate Safety and Effect of SAR-443122 on Immune System in Severe COVID-19 |
Coronavirus disease 19 infection, Inflammatory disease, Lung disease |
DNL-758 alone |
RIP-1 kinase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sanofi SA |
|
|
2020-07-20 |
2021-01-31 |
2020-002104-39, NCT04469621, PDY16879, U1111-1250-1185 |
Phase 1b Clinical |
Not yet recruiting |
0 |
6 Months |
67 |
Clinical Sciences & Operations |
2020-07-16 |
| Effect of insulins (a chemical in our body which decreases blood sugar) sugar lowering effect in COVID-19 patients |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
All India Institute of Medical Sciences |
|
India |
2020-07-19 |
|
CTRI/2020/07/026474 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
125 |
Dr Souvik Maitra |
2020-07-19 |
| Melatonin Agonist on Hospitalized Patients With Confirmed or Suspected COVID-19 |
Coronavirus disease 19 infection |
ramelteon alone |
Melatonin MT1 receptor agonist, Melatonin MT2 receptor agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Associação Fundo de Incentivo à Pesquisa |
|
Brazil |
2020-09-30 |
2021-03-31 |
MELCOV2020, NCT04470297 |
Phase 2 Clinical |
Not yet recruiting |
1 |
6 Months |
100 |
Dalva Poyares, Ronaldo D Piovezan, PhD |
2020-07-17 |
| ImmCoV: Are SARS-CoV-2 Specific Antibodies a Correlate for Protection? |
Coronavirus disease 19 infection |
antibody test alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Institute of Tropical Medicine, Belgium |
Antwerp University Hospital, Jessa Hospital, Mensura, Sciensano, University of Antwerp |
Belgium |
2020-07-31 |
2021-07-31 |
1412/20, ImmCoV, NCT04469634 |
Phase Not Applicable |
Not yet recruiting |
2 |
12 Months |
150 |
Herman Goossens, MD, PhD, Kevin K. Ariën, PhD, Koen Magerman, MD, Leen Van Loon, MD, Leo Heyndrickx, Pierre Van Damme, MD, PhD, Sam Van Goethem, MD |
2020-07-16 |
| CoNFINE-C: Limitations of social life in the context of the COVID-19 pandemic - effects on physical performance and health-related quality of life of older people (part C) |
Coronavirus disease 19 infection |
Milon circle training alone |
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Carl Von Ossietzky Universität Oldenburg |
|
Germany |
2020-06-26 |
|
2020-061, CoNFINE-C, DRKS00022438 |
Phase Not Applicable |
Recruiting |
1 |
|
300 |
Jessica Koschate, Tania Zieschang |
2020-07-16 |
| Observational Study of Sensitivity and Specificity of COVID-19 Screening and Diagnostics in COVID-19 Infected Individuals |
Coronavirus disease 19 infection |
COVID-LAMP test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
InnoDx Solutions Pvt Ltd |
|
India |
2020-07-13 |
|
CTRI/2020/07/026451 |
Phase Not Applicable |
Not yet recruiting |
2 |
|
150 |
Dr Sandeep Verma |
2020-07-16 |
| COVID 19 Seroprevalence Amongst Healthcare Workers in JHAH |
Coronavirus disease 19 infection |
serology test alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Johns Hopkins Aramco Healthcare |
|
Saudi Arabia |
2020-07-19 |
2021-06-15 |
IRB0001, NCT04469647 |
Phase Not Applicable |
Recruiting |
1 |
10 Months |
1200 |
|
2020-07-17 |
| Extent and spread of SARS-CoV-2 (COVID-19) infections in the first acute phase in the area of Vorarlberg |
Coronavirus disease 19 infection |
ELISA alone |
|
|
NEXTCLINIC IVF |
|
Austria |
2020-07-05 |
|
DRKS00022418, EK-2-10/2020 |
Phase Not Applicable |
Recruiting |
1 |
|
1000 |
Maximilian Murtinger |
2020-07-17 |
| Infection rate of Covid-19 among medical staff in GP practices in North Rhine-Westphalia (Germany) |
Coronavirus disease 19 infection |
Antibody test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universitatsklinikum Essen |
|
Germany |
2020-06-10 |
|
20-9339-BO, DRKS00021788 |
Phase Not Applicable |
Recruiting |
1 |
|
900 |
Dorothea Dehnen |
2020-07-17 |
| COVE: A Study to Evaluate Efficacy, Safety, and Immunogenicity of mRNA-1273 Vaccine in Adults Aged >/= 18 Years to Prevent COVID-19 |
Coronavirus disease 19 infection |
mRNA-1273 alone |
COVID19 Spike glycoprotein modulator |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Catalent Inc, ModeRNA Therapeutics |
Biomedical Advanced Research and Development Authority (BARDA), National Institute of Allergy and Infectious Diseases, US Department of Health and Human Services |
US |
2020-07-27 |
2022-10-27 |
75A50120C00034, COVE, MRNA-1273-P301, NCT04470427 |
Phase 3 Clinical |
Not yet recruiting |
0 |
27 Months |
30000 |
Moderna Clinical Trials |
2020-07-17 |
| Clinical characteristics and disease progression in early-stage COVID-19 patients in South Korea |
Coronavirus disease 19 infection, SARS coronavirus infection |
angiotensin 2 receptor blockers alone, dipeptidyl peptidase-4 inhibitors alone, ibuprofen alone, lopinavir + ritonavir alone |
HIV protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Severance Hospital |
Severance Hospital |
South Korea |
2020-03-23 |
2020-04-27 |
AFMC-20015-IRB-20-015, KCT0005226 |
Phase Not Applicable |
Completed |
1 |
1 Month |
293 |
Min Hyuk Choi |
2020-07-17 |
| Role of Co-trimoxazole in Severe COVID-19 Patients |
Coronavirus disease 19 infection, Hypoxia, Respiratory failure |
antibiotic therapy alone, hydration therapy alone, steroid therapy alone, thromboprophylaxis alone, Variable regimens including co-trimoxazole , oxygen , paracetamol |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Bangabandhu Sheikh Mujib Medical University |
Anwar Khan Mordern Medical College and Hospital, Dhaka, Mugda Medical College and Hospital, Dhaka |
Bangladesh |
2020-07-12 |
2021-01-30 |
BSMMU/2020/6969, NCT04470531 |
Phase 2 Clinical |
No longer recruiting |
1 |
6 Months |
94 |
Prof. Dr. Shohael Mahmud Arafat |
2020-07-16 |
| GUARDS-1: Aprepitant Injectable Emulsion in Patients With COVID-19 |
Coronavirus disease 19 infection |
Variable regimens including aprepitant (iv/neurokinin-1 (NK1) receptor antagonist/chemotherapy induced nausea and vomiting/COVID-19), Heron Therapeutics , dexamethasone , remdesivir |
COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, NK1 receptor antagonist, RNA polymerase modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Heron Therapeutics Inc |
|
Puerto Rico, US |
2020-07-16 |
2020-10-31 |
GUARDS-1, HTX-019-202, NCT04470622 |
Phase 2 Clinical |
Recruiting |
4 |
3 Months |
100 |
Neil Clendeninn, PhD, MD |
2020-07-20 |
| Safety and Immunogenicity Study of an Inactivated SARS-CoV-2 Vaccine for Preventing Against COVID-19 in People Aged >/= 60 Years |
Coronavirus disease 19 infection |
SARS-CoV-2 vaccine (inactivated/Vero cells/intramuscular, COVID-19), Institute of Medical Biology Chinese Academy of Medical Sciences alone |
|
Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Chinese Academy of Medical Sciences |
West China Second University Hospital, Yunnan Center for Disease Control and Prevention |
China |
2020-07-10 |
2021-11-30 |
20200402, NCT04470609 |
Phase 1/Phase 2 Clinical |
Recruiting |
1 |
16 Months |
471 |
Qin Yu, Xiaoqiang Liu |
2020-07-17 |
| A clinical trial of BNT-162b1 in China for COVID-19 |
Coronavirus disease 19 infection |
BNT-162b1 alone |
COVID19 Spike glycoprotein modulator |
|
Shanghai Fosun Pharmaceutical Industry Development Co Ltd |
|
China |
|
|
|
Phase Not Applicable |
Not yet recruiting |
1 |
|
|
|
2020-07-16 |
| An Observational, Cohort Trial of Outcomes and Antibody Responses Following Treatment With COVID19 Convalescent Plasma in Hospitalized COVID-19 Patients |
Coronavirus disease 19 infection |
convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Colorado, Denver, US |
|
US |
2020-04-30 |
2021-04-30 |
20-0986, NCT04471051 |
Phase 2 Clinical |
Recruiting |
0 |
12 Months |
150 |
Carl Bernas, MD, Dan Monkowski, MD, Eric Richards, MD, John D Beckham, MD, Lakshmi Chauhan, MD, Michele Loi, MD, Timothy Jenkins, MD |
2020-07-17 |
| Functional Exhaustion of T Cells in COVID19 Patients |
Coronavirus disease 19 infection |
flow cytometry alone |
|
Healthy volunteers accepted |
Assiut University |
|
Egypt |
2020-07-31 |
2020-11-30 |
NCT04470323, T CELLS |
Phase Not Applicable |
Not yet recruiting |
1 |
4 Months |
100 |
Dr Hebatallah Hassan, Hebatallah Hassan, Lecturer |
2020-07-17 |
| Impact of COVID-19 Pandemic on the Psychological Wellbeing of Healthcare Professionals in India |
Coronavirus disease 19 infection, Psychiatric disorder |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Max Healthcare Institute Ltd, India |
|
India |
2020-05-18 |
2020-09-30 |
NCT04469660, ONCO SURVEY_COVID-19 |
Phase Not Applicable |
Recruiting |
1 |
4 Months |
1300 |
Hiba Siddiqui, Ramandeep Arora, Ramandeep S Arora, Siddiqui |
2020-07-17 |
| Epidemioligical reserch on COVID-19 at Osaka |
Coronavirus disease 19 infection, Hypoxia |
|
|
|
Osaka Saiseikai Nakatsu Hospital |
|
Japan |
2020-02-13 |
|
2020-7, UMIN000041102 |
Phase Not Applicable |
Recruiting |
1 |
|
1200 |
Tetsuya Ueda |
2020-07-20 |
| Is Thymus Size of Infants Who Born to COVID-19 Positive Mothers Associated With Neonatal Morbidities? |
Coronavirus disease 19 infection |
chest X-ray alone |
|
Healthy volunteers accepted, Newborn Infants (up to 5 months) |
Istanbul Bakirkoy Maternity and Children Diseases Hospital |
|
Turkey |
2020-05-30 |
2020-10-30 |
KSSEAH--CT, NCT04470739 |
Phase Not Applicable |
Recruiting |
1 |
5 Months |
20 |
Seda Yilmaz Semerci |
2020-07-16 |
| RECOVER: Camostat Mesilate Treating Patients With Hospitalized Patients With COVID-19 |
Coronavirus disease 19 infection |
camostat mesylate alone, standard of care alone |
Serine protease inhibitor, Transmembrane serine protease 2 inhibitor, Trypsin inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Academic and Community Cancer Research United |
|
US |
2020-07-15 |
2020-09-15 |
CAM20CV, NCT04470544, RECOVER |
Phase 2 Clinical |
Not yet recruiting |
0 |
2 Months |
264 |
ACCRU Operations, Alan H Bryce, M.D. |
2020-07-16 |
| A clinical trial of MVC-COV1901 vaccine for the prevention of COVID-19 |
Coronavirus disease 19 infection |
MVC-COV1901 alone |
COVID19 Spike glycoprotein modulator |
|
Medigen Vaccine Biologics Corp |
|
Taiwan |
|
|
|
Phase Not Applicable |
Planned |
1 |
|
|
|
2020-07-15 |
| A trial to compare outcomes in hospitalized COVID-19 patients treated with standard drug treatments alone or standard treatments combined with an oral bacteriotherapy |
Coronavirus disease 19 infection, Diarrhea |
antibiotics alone, bacteriotherapy alone, hydroxchloroquine plus tocilizumab |
|
|
Exegi Pharma LLC |
|
Italy |
|
|
|
Phase 2 Clinical |
Status not specified |
1 |
|
70 |
Giancarlo Ceccarelli |
2020-07-15 |
| A phase II, multicenter, randomized, double-blind, placebo-controlled study to evaluate the safety and efficacy of EC-18 in preventing the progression of COVID-19 infection to severe pneumonia or ARDS |
Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia |
mosedipimod alone |
CCL26 gene inhibitor, TLR modulator |
|
Enzychem Lifesciences Corp |
|
US |
|
|
|
Phase 2 Clinical |
Planned |
0 |
|
60 |
Dr. Cameron Robert Wolfe |
2020-07-15 |
| COV-NI: Treatment of COVID-19 by Nebulization of Inteferon Beta 1b Efficiency and Safety Study |
Coronavirus disease 19 infection |
antibiotics therapy alone, inteferon beta 1b alone, oxygen support alone, standard care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire D Amiens |
|
France |
2020-07-31 |
2021-03-31 |
COV-NI, NCT04469491, PI2020-843-0041 |
Phase 2 Clinical |
Not yet recruiting |
1 |
8 Months |
60 |
Aurélien Mary, MD, Jean Luc Jean Luc Schmit, Pr, Jean-Philippe Lanoix, MD, Michel Brazier, Pr |
2020-07-16 |
| Coronavirus infection in immunosuppressed children |
Coronavirus disease 19 infection, Respiratory disease |
online questionnaire alone |
|
Adolescents (13-17 yrs) |
University Hospital Southampton NHS Foundation Trust |
British Paediatric Allergy, Immunity and Infection Group |
UK |
2020-03-16 |
2021-06-15 |
CPMS 45332, ISRCTN10175886 |
Phase Not Applicable |
Recruiting |
41 |
15 Months |
400 |
Dr DeGraaf, Prof Saul Faust |
2020-07-17 |
| Elmo Respiratory Support Project - COVID-19 |
Coronavirus disease 19 infection, Respiratory failure, Respiratory insufficiency |
Elmo system alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Escola de Saúde Pública do Ceará |
|
Brazil |
2020-08-31 |
2020-12-31 |
4.104.233, NCT04470258 |
Phase Not Applicable |
Not yet recruiting |
1 |
4 Months |
10 |
MARCELO HOLANDA, Doctor |
2020-07-16 |
| EPISODES: Investigating the impact of the coronavirus (COVID-19) pandemic on children presenting to emergency departments across Europe |
Coronavirus disease 19 infection |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Imperial College London |
|
France, Italy, UK, Spain, Malta, Hungary, Netherlands |
2020-06-14 |
2020-10-31 |
EPISODES, IRAS 284008, ISRCTN91495258 |
Phase Not Applicable |
No longer recruiting |
8 |
4 Months |
|
Dr Nijman |
2020-07-17 |
| COpregVID: Evaluating Clinical Parameters of COVID-19 in Pregnancy |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Chelsea & Westminster NHS Trust |
|
UK |
2020-07-31 |
2021-12-02 |
283995, C&W20/034, COpregVID, NCT04470583 |
Phase Not Applicable |
Not yet recruiting |
1 |
16 Months |
116 |
Natasha Singh, Natasha Singh, MRCOG, MD, Research Delivery Operations Manager |
2020-07-20 |
| MATIS: Multi-arm trial of Inflammatory Signal Inhibitors for COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
best supportive treatment alone, fostamatinib disodium alone, ruxolitinib alone |
Jak1 tyrosine kinase inhibitor, Jak2 tyrosine kinase inhibitor, Syk tyrosine kinase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Joint Research Office |
|
UK |
2020-07-09 |
|
2020-001750-22, 20HH5926, MATIS |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
|
186 |
Tina Shturova-Chakreska |
2020-07-16 |
| Safety, Tolerability, and Pharmacokinetics of SAB-185 in Ambulatory Participants With COVID-19 |
Coronavirus disease 19 infection |
SAB-185 alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
CSL Behring LLC, SAB Biotherapeutics Inc |
Biomedical Advanced Research and Development Authority (BARDA), Joint Program Executive Office for Chemical, Biological, Radiological, and Nuclear Defense, US Department of Defense |
North America |
2020-07-31 |
2020-12-31 |
NCT04469179, SAB-185-102 |
Phase 1b Clinical |
Not yet recruiting |
0 |
5 Months |
21 |
Moronke Iyoha |
2020-07-16 |
| Effect of a special nutritional oral supplement use on inflammation in patients with COVID-19 |
Coronavirus disease 19 infection, Inflammatory disease, Respiratory distress syndrome |
Nutren Senior alone, drug treatment ( institutional protocol) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Universidade do Estado da Bahia |
|
Brazil |
2020-06-01 |
|
4.031.187, CAAE: 31801820.0.0000.0057 - CAAE, RBR-7jrxqm, U1111-1252-3270 |
Phase Not Applicable |
Recruiting |
1 |
|
50 |
Magno Conceição das Merce, Rodrigo Fernandes Weyll Pimentel |
2020-07-20 |
| Assessment cardiorespiratory in recovered Covid-19 patients |
Coronavirus disease 19 infection |
cardiopulmonary exercise alone, electromyography alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universidade Federal da Paraiba |
|
Brazil |
2020-07-01 |
|
34234720.0.0000.5184, 4.132.248, RBR-6xqcr4, U1111-1254-8568 |
Phase Not Applicable |
Recruiting |
1 |
|
150 |
Amilton da Cruz Santos, Maria do Socorro Brasileiro-Santos, Murillo Frazao |
2020-07-20 |
| RESOLVE: Regulatory T Cell Transfusion For Lung Injury Due to COVID-19 Pneumonia |
Coronavirus disease 19 infection, Lung injury, Respiratory distress syndrome, Viral pneumonia |
CK-0802 alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cellenkos Inc |
Biomedical Advanced Research and Development Authority (BARDA) |
US |
2020-08-30 |
2021-09-30 |
CK0802.501.1, NCT04468971, RESOLVE |
Phase 1 Clinical |
Not yet recruiting |
0 |
13 Months |
45 |
Darryl Adams, MD, Douglas Gladstone, MD, Jason Mock, MD, PhD, Kevin Harris, MD, Tara Sadeghi |
2020-07-16 |
| Heart Hive COVID-19 Study: The Heart Hive COVID-19 Study |
Coronavirus disease 19 infection, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Myocardial disease, Restrictive cardiomyopathy |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Imperial College London |
|
UK |
2020-07-31 |
2022-07-31 |
20IC6036-, Heart Hive COVID-19 Study, NCT04468256 |
Phase Not Applicable |
Not yet recruiting |
1 |
24 Months |
1000 |
James S Ware, The Heart Hive |
2020-07-15 |
| ACEI or ARB and COVID-19 Severity and Mortality in US Veterans |
Coronavirus disease 19 infection, Hypertension |
angiotensin receptor blocker therapy alone, angiotensin-converting enzyme inhibitor therapy alone, azilsartan alone, benazepril alone, candesartan alone, captopril alone, enalapril alone, eprosartan alone, fosinopril alone, irbesartan alone, lisinopril alone, losartan alone, moexipril alone, olmesartan medoxomil alone, perindopril alone, quinapril hydrochloride alone, ramipril alone, telmisartan alone, trandolapril alone, valsartan alone |
ACE inhibitor, Angiotensin I receptor antagonist, Angiotensin II AT-1 receptor antagonist, Angiotensin II receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Utah |
Boston University, Columbia University, Edith Nourse Rogers Memorial Veterans Hospital, Johns Hopkins Bloomberg School of Public Health, MedStar Georgetown University Hospital, Northwestern University, University of Florida, University of Pennsylvania, VA Salt Lake City Health Care System, Wake Forest University Health Sciences, US |
US |
2020-01-19 |
2020-07-31 |
00132408, NCT04467931 |
Phase Not Applicable |
No longer recruiting |
0 |
6 Months |
10000 |
Adam P Bress, PharmD, MS |
2020-07-16 |
| VRQOL in Cataract Patients During the COVID-19 Pandemic |
Cataract, Coronavirus disease 19 infection |
|
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Medizinische Universität Innsbruck |
|
|
2020-07-31 |
2021-03-31 |
NCT04468308, VRQOL CATARACT COVID-19 |
Phase Not Applicable |
Not yet recruiting |
0 |
8 Months |
116 |
Claus Zehetner, Dr., Teresa Rauchegger, Dr. |
2020-07-15 |
| Perceived Fear Towards Handling Covid-19 Cases and Its Associated Factors among Nurses and Allied Health Professionals in Penang |
Coronavirus disease 19 infection |
|
|
|
Seberang Jaya Hospital |
|
Malaysia |
2020-10-01 |
2021-10-31 |
NMRR-20-1422-55669 |
Phase Not Applicable |
Not yet recruiting |
1 |
13 Months |
|
Ketua Jururawat vimala a/p j.kasinathan |
2020-07-15 |
| Evaluation of 6-month HIV Treatment Dispensing in South Africa |
Coronavirus disease 19 infection, HIV infection |
6-month medication dispensing care alone, antiretroviral therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Boston University |
Bill & Melinda Gates Foundation, University of Witwatersrand |
South Africa |
2020-08-31 |
2022-12-31 |
H-40512, NCT04468789, OPP1192640 |
Phase Not Applicable |
Not yet recruiting |
1 |
28 Months |
150945 |
Sophie Pascoe, Sydney Rosen |
2020-07-16 |
| Safety and Effectiveness of Siddha Sastric Medicines for the Management of Covid-19 |
Coronavirus disease 19 infection |
Variable regimens including Adathodai Manapagu , Brammhanandha bairavam , Kaba Sura Kudineer Chooranam , Thaleesadhi Chooranam Mathirai |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Almaa Siddha Care Multi Speciality Hospital, Central Council for Research in Siddha |
|
India |
2020-07-15 |
|
CTRI/2020/07/026470 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
200 |
Dr M Pitchiah Kumar, Dr V THANIGAVELAN, Prof Dr K Kanakavalli |
2020-07-15 |
| AGILE: Seamless phase I/IIa platform for the rapid evaluation of candidates for COVID-19 treatment. A randomized, phase I/II study to determine the safety and effectiveness of multiple drugs for the treatment of COVID-19 |
Coronavirus disease 19 infection |
EIDD-2801 alone, nomacopan alone |
Complement C5 factor inhibitor, Leukotriene BLT receptor antagonist, RNA polymerase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The University of Liverpool |
|
UK |
2020-05-12 |
|
2020-001860-27, AGILE, UoL001542 |
Phase 1/Phase 2 Clinical |
Recruiting |
1 |
|
250 |
Ellice Marwood |
2020-07-16 |
| Rapid diagnostic test for the detection of COVID-19 antibodies |
Coronavirus disease 19 infection |
rapid diagnostic test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
HealthCubed India Pvt Ltd |
|
India |
2020-07-14 |
|
CTRI/2020/07/026469 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Dr Monila Patel |
2020-07-16 |
| Epidemiology and outcomes of COVID-19 in Udupi |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kasturba Medical College, Manipal |
|
India |
2020-07-16 |
|
CTRI/2020/07/026472 |
Phase Not Applicable |
Not yet recruiting |
2 |
|
500 |
Dr Kavitha Saravu, Dr Shashikiran Umakanth |
2020-07-15 |
| Drug Trial to Evaluate Efficacy and Safety of an Ayurvedic Formulation as Adjunct Treatment to Standard of Care for the Management of Mild to Moderate COVID-19 Patients |
Coronavirus disease 19 infection |
AYUSH 64 alone, Samshamani Vati Plus alone, Yashtimadhu alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Indian Institute of Integrative Medicine, Jammu |
|
India |
2020-07-20 |
|
COVID 19/AYUSH-ICMR 2020/Adjunct Protocol-AF-III, CTRI/2020/07/026468 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
140 |
Dr Dilip Mondhe, Dr Umar Quadari, Mr Chandu Devanpally, Pranjal Ausekar |
2020-07-17 |
| To Determine the Efficacy of Neurokinin 1 Receptor Antagonist as a Therapeutic Tool Against Cytokine Storm and Respiratory Failure in Covid-19 Patients |
Coronavirus disease 19 infection, Lung injury, Multiple organ failure, Respiratory failure, Shock, Systemic inflammatory response syndrome |
NK-1R antagonist therapy alone, dexamethasone plus fosaprepitant |
NK1 receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Health Sciences Lahore |
Bahria International Hospital, University of Lahore, Main Campus |
Pakistan |
2020-06-15 |
2020-08-30 |
NCT04468646, UNIVERSITYHSL-NK1R |
Phase 3 Clinical |
Recruiting |
1 |
2 Months |
100 |
Ahad Qayyum, MBBS, Ahad Qayyum, MBBS,MRCP, Fridoon Jawad Ahmad, PhD, Javed Akram, MBBS, Muhammad Asim Rana, MBBS, Muhammad Asim o Rana, MBBS, Prof. Dr. Fridoon Jawad Ahmad, Riffat Mehboob, PhD |
2020-07-16 |
| Safety, Tolerability, and Pharmacokinetics of SAB-185 in Healthy Participants |
Coronavirus disease 19 infection |
SAB-185 alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
SAB Biotherapeutics Inc |
Joint Program Executive Office for Chemical, Biological, Radiological, and Nuclear Defense, US Department of Health and Human Services |
|
2020-07-31 |
2020-12-31 |
NCT04468958, SAB-185-101 |
Phase 1 Clinical |
Not yet recruiting |
0 |
5 Months |
28 |
Moronke Iyoha |
2020-07-16 |
| CognitiVID: Early Cognitive Assessment and Evolutionary Monitoring of Patients With Severe ARDS on SARS-CoV2 Viral Pneumonia Requiring Mechanical Ventilation |
Cognitive disorder, Coronavirus disease 19 infection, Hypoxia, Respiratory distress syndrome, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Groupe Hospitalier Paris Saint-Joseph |
|
France |
2020-06-01 |
2021-12-31 |
COGNITIVID, CognitiVID, NCT04468035 |
Phase Not Applicable |
Recruiting |
1 |
19 Months |
30 |
Clement Vialatte de Pémille, MD, Clément Vialatte de Pémille, MD, Helene BEAUSSIER, PharmD, pHD |
2020-07-16 |
| Tofacitinib in Hospitalized Patients With COVID-19 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
standard of care alone, tofacitinib citrate (oral, inflammation), Pfizer alone |
JAK tyrosine kinase inhibitor, Jak1 tyrosine kinase inhibitor, Jak3 tyrosine kinase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sociedade Beneficente Israelita Brasileira Hospital Albert Einsten |
Pfizer Inc |
|
2020-08-07 |
2021-01-31 |
34810620.0.1001.0071, NCT04469114 |
Phase 2 Clinical |
Not yet recruiting |
0 |
5 Months |
260 |
Patricia O Guimaraes, MD, PhD |
2020-07-16 |
| Antiviral Agents Against COVID-19 Infection |
Coronavirus disease 19 infection |
atazanavir alone, daclatasvir alone, favipiravir alone, sofosbuvir alone |
HIV GAG POL polyprotein inhibitor, HIV GAG protein inhibitor, HIV-1 protease inhibitor, Hepatitis C virus NS5B polymerase inhibitor, Hepatitis C virus protein NS5A inhibitor, RNA polymerase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital do Coracao |
|
Brazil |
2020-08-01 |
2020-10-31 |
ANTIVIRAL, NCT04468087 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
3 Months |
125 |
Israel Maia, PhD |
2020-07-15 |
| Characteristics of TraceTogether Users |
Coronavirus disease 19 infection |
TraceTogether app alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry |
Yale-NUS College |
|
Singapore |
2020-03-08 |
2020-07-31 |
510D, NCT04468581 |
Phase Not Applicable |
No longer recruiting |
1 |
4 Months |
500 |
|
2020-07-15 |
| A trial to investigate the prophylactic potential of JS-016 in COVID-19 high-risk population |
Coronavirus disease 19 infection |
JS-016 alone |
COVID19 Spike glycoprotein inhibitor |
|
Shanghai Junshi Biosciences Co Ltd |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-07-14 |
| CANDIDATE: Cannabidiol for COVID-19 Patients With Mild to Moderate Symptoms |
Coronavirus disease 19 infection, Lower respiratory tract infection, Upper respiratory tract infection, Viral pneumonia |
home isolation alone, Variable regimens including cannabidiol , dipyrone , paracetamol |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Sao Paulo |
Conselho Nacional de Desenvolvimento Cientifico e Tecnologico - CNPq, Fundacao de Amparo a Pesquisa do Estado Sao Paulo |
Brazil |
2020-07-06 |
2020-10-31 |
CANDIDATE, CANDIDATE STUDY, NCT04467918 |
Phase 2/Phase 3 Clinical |
Recruiting |
2 |
3 Months |
100 |
Jose ALEXANDRE DE S CRIPPA, MD, PhD, Julia C Pacheco, B.Pharm, Julia Cozar Pacheco, PharmD |
2020-07-15 |
| Specimen Collection Study Protocol |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Biomerica Inc |
|
US |
2020-07-07 |
2020-07-31 |
CV19-COL-004, NCT04468386 |
Phase Not Applicable |
Recruiting |
1 |
|
40 |
Carolyn Shoup, Elisabeth Laderman, Ph.D. |
2020-07-15 |
| A phase II/III trial to evaluate JS-016 for the treatment of severe and critical Coronavirus disease 19 infection patients |
Coronavirus disease 19 infection |
JS-016 alone |
COVID19 Spike glycoprotein inhibitor |
|
Shanghai Junshi Biosciences Co Ltd |
|
|
|
|
|
Phase 2/Phase 3 Clinical |
Planned |
0 |
|
|
|
2020-07-14 |
| A phase Ib trial to evaluate JS-016 in non-severe COVID-19 patients |
Coronavirus disease 19 infection |
JS-016 alone |
COVID19 Spike glycoprotein inhibitor |
|
Shanghai Junshi Biosciences Co Ltd |
|
|
|
|
|
Phase 1b Clinical |
Planned |
0 |
|
|
|
2020-07-14 |
| Opaganib, a Sphingosine Kinase-2 (SK2) Inhibitor in COVID-19 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
opaganib alone, standard of care alone |
Dihydroceramide delta 4 desaturase inhibitor, Sphingosine kinase 2 inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
RedHill Biopharma Ltd |
|
Italy, Russian Federation, Brazil, US, Mexico, UK |
2020-07-31 |
2020-12-31 |
ABC-201, NCT04467840 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
6 |
5 Months |
270 |
Mark L Levitt, MD, Mark Levitt, MD, Vered Katz Ben-Yair, MSc |
2020-07-20 |
| A multicenter, retrospective, observational study to evaluate the role of hydroxychloroquine therapy alone and in combination with azithromycin in hospitalized patients positive for COVID-19 |
Coronavirus disease 19 infection |
azithromycin alone, hydroxychloroquine alone, azithromycin plus hydroxychloroquine |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Henry Ford Health System |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
|
|
2020-07-16 |
| A clinical study to evaluate the immune responses of patients with inflammatory skin diseases in the setting of COVID-19 infection |
Coronavirus disease 19 infection |
dupilumab alone |
IL-13 receptor antagonist, IL-4 receptor antagonist |
|
Mount Sinai School of Medicine |
National Institutes of Health |
|
|
|
|
Phase Not Applicable |
Not yet recruiting |
0 |
|
|
Dr. Guttman-Yassky |
2020-07-14 |
| Evaluation of an Alternative Method of Obtaining Viral RNA for the Detection of SARS-CoV-2 Virus Using PCR |
Coronavirus disease 19 infection |
AAA-Safe medium transport alone, biological sampling alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Neurognos |
|
Chile |
2020-06-02 |
2020-09-25 |
NCT04468217, PRO-02 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
150 |
Alejandro Bisquertt Zavala, David Chamorro Veloso, José Miguel Vega Soto |
2020-07-15 |
| Interest of the Dosage of Ferritin/Glycosylated Ferritin in COVID-19 |
Coronavirus disease 19 infection |
serological test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospices Civils De Lyon |
|
France |
2020-06-29 |
2020-12-31 |
2020_FERRIGLY COVID, NCT04469153 |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
57 |
Maxime FAUTER, Yvan Jamilloux, Yvan jamilloux |
2020-07-15 |
| COVAS: Influence of COVID-19 on Vascular Endothelial Function |
Cardiovascular disease, Coronavirus disease 19 infection |
carotid artery reactivity testing alone, cold pressor test alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Radboud University |
Bernhoven Hospital |
Netherlands |
2020-07-13 |
2021-09-30 |
COVAS, NCT04468412, NL2020-6555 |
Phase Not Applicable |
Not yet recruiting |
1 |
14 Months |
200 |
Andre S van Petersen, PhD, Loes H Willems, MD |
2020-07-15 |
| Treatment of Critically Ill Patients With Covid-19 With Convalescent Plasma |
Coronavirus disease 19 infection, Multiple organ failure, Respiratory distress syndrome, Septic shock |
Convalescent plasma alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital de Infecciosas Francisco Javier Muniz |
|
Argentina |
2020-06-25 |
2021-06-30 |
1725, NCT04468009 |
Phase 2 Clinical |
Recruiting |
1 |
12 Months |
36 |
Carlos A Gonzalez, MD |
2020-07-17 |
| The Study of Quadruple Therapy Zinc, Quercetin, Bromelain and Vitamin C on the Clinical Outcomes of Patients Infected With COVID-19 |
Coronavirus disease 19 infection |
Variable regimens including bromelain , quercetin , vitamin C , zinc |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ministry of Health Saudi Arabia |
|
Saudi Arabia |
2020-06-20 |
2020-07-30 |
20-95M, NCT04468139 |
Phase 4 Clinical |
Recruiting |
1 |
1 Month |
60 |
Amr kamel khalil Ahmed, Hiba Hamadelnil elsaeed, abdullah Alqattan, amr ahmed, yousef albalawi |
2020-07-15 |
| Online Positive Psychology Intervention for Depression and Anxiety Due to COVID-19 |
Anxiety disorder, Coronavirus disease 19 infection, Depression |
Online Intervention Mental Health COVID-19 with chat alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Universidad Internacional de Valencia |
Universidad Autonoma de Ciudad Juarez, Universidad Nacional Autonoma De Mexico |
Mexico |
2020-05-20 |
2020-09-15 |
NCT04468893, VIU-PP |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
128 |
Alejandro Dominguez Rodriguez, PhD, Alejandro Domínguez Rodríguez, External professor, Anabel de la Rosa Gómez, PhD, Flor Rocio Ramirez-Martinez, PhD, Jasshel Teresa Salinas-Saldivar, MD, María Jesús Hernández Jimenez, PhD, Oscar Armando Esparza Villar, PhD, Paulina Arenas Landgrave, PhD, Priscila Montañez Alvarado, PhD, Sofía Cristina Martínez Luna, MD |
2020-07-15 |
| PGD in Malaysia, Covid-19 Pandemic |
Coronavirus disease 19 infection |
|
|
|
Hospital Permai |
|
Malaysia |
2020-06-22 |
2021-11-01 |
NMRR-20-1416-54974 |
Phase Not Applicable |
Recruiting |
1 |
16 Months |
|
Dr Fabian Sunil Dass A/L A S Dass, Dr Norazam Bin Harun |
2020-07-19 |
| A trial to evaluate JS-016 for the treatment of patients with Coronavirus disease 19 infection |
Coronavirus disease 19 infection |
JS-016 alone |
COVID19 Spike glycoprotein inhibitor |
|
Eli Lilly & Co, Shanghai Junshi Biosciences Co Ltd |
|
US |
2020-06-30 |
|
|
Phase Not Applicable |
Recruiting |
1 |
|
|
|
2020-07-14 |
| COVID-AD: Impact of the COVID-19 Pandemic on Symptoms of Anxiety Disorders |
Agoraphobia, Anxiety disorder, Coronavirus disease 19 infection, Panic disorder, Social phobia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Humboldt University of Berlin |
|
Germany |
2020-07-16 |
|
2020-41, COVID-AD, DRKS00022280 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
110 |
Andrea Ertle |
2020-07-15 |
| Do Childhood Measles and DTaP Vaccination Decrease the Mortality Rate Caused by COVID-19 in OECD Countries? |
Coronavirus disease 19 infection |
DTaP (diphtheria, tetanus, pertussis) vaccination alone, measles vaccination alone |
|
Healthy volunteers accepted |
Istanbul Bakirkoy Maternity and Children Diseases Hospital |
|
Turkey |
2020-02-01 |
2020-07-01 |
KSSEAH--0965, NCT04468802 |
Phase Not Applicable |
Completed |
1 |
5 Months |
32 |
Ramazan Guven |
2020-07-16 |
| Psychosocial functioning and lifestyle changes of German university students during the coronavirus (COVID-19) pandemic: An online survey |
Coronavirus disease 19 infection, Psychiatric disorder |
|
|
|
UniversitätsKlinikum Leipzig |
|
Germany |
2020-07-09 |
|
22062020, DRKS00022424 |
Phase Not Applicable |
Recruiting |
1 |
|
10000 |
Christine Rummel-Kluge |
2020-07-15 |
| Co-Kl-Ak: Prevalence of SARS-CoV-2 Infections in the Employees of the Pius-Hospital Oldenburg, Confirmed Through Virus Antibody Testing - COVID-19 |
Coronavirus disease 19 infection |
blood sampling alone |
|
|
Pius-Hospital Oldenburg |
|
Germany |
2020-06-22 |
|
2020-095, Co-Kl-Ak, DRKS00022259 |
Phase Not Applicable |
Recruiting |
1 |
|
1250 |
Haitham Mansour, Uslar Verena |
2020-07-15 |
| CoNFINE-B: Limitations of social life in the context of the COVID-19 pandemic - Effects on physical performance and health-related quality of life of older people (part B) |
Coronavirus disease 19 infection |
Milon circle training alone |
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Carl Von Ossietzky Universität Oldenburg |
|
Germany |
2020-08-01 |
|
2020-061, CoNFINE-B, DRKS00022433 |
Phase Not Applicable |
Recruiting |
1 |
|
2000 |
Ms. Dr. Jessica Koschate, Ms. Prof. Dr. med. Tania Zieschang |
2020-07-15 |
| COCO-M: Consequences of the COVID-19 pandemic for surgical patient treatment in a tertiary care center in Munich |
Coronavirus disease 19 infection, Surgical procedure |
|
|
|
Technical University of Munich |
|
Germany |
2020-03-02 |
|
172/20 S, COCO-M, DRKS00022147 |
Phase Not Applicable |
Recruiting |
1 |
|
500 |
Jens Gempt |
2020-07-14 |
| A clinical trial to study the effect and safety of the Siddha medicines in patients with Corona Virus disease |
Coronavirus disease 19 infection |
Siddha Sasthric Medicines alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Ministry of Ayush |
|
India |
2020-07-20 |
|
CTRI/2020/07/026471 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
60 |
Dr D Sasikumar, Dr M Kannan, Dr P Sathiyarajeswaran |
2020-07-16 |
| A Phase I Clinical trial of NDC-1308 in COVID-19 patients |
Coronavirus disease 19 infection |
NDC-1308 alone |
Estrogen receptor beta agonist |
|
Endece Inc |
|
|
|
|
|
Phase 1 Clinical |
Planned |
0 |
|
|
|
2020-07-14 |
| Effects of the COVID-19 crisis on the experiences of psychiatric patients in the combination setting of group and individual psychotherapy treatment |
Coronavirus disease 19 infection, Psychiatric disorder |
psychotherapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
OAGG psychotherapeutic ambulance GmbH |
|
Austria |
2020-06-12 |
|
DRKS00022387 |
Phase Not Applicable |
Recruiting |
1 |
|
450 |
Ms. Mag. Hannah Bischof |
2020-07-15 |
| RECOVER: Using the blood pressure medication losartan to improve outcomes for patients with SARS CoV-2 |
Coronavirus disease 19 infection |
losartan alone, standard treatment alone |
Angiotensin II AT-1 receptor antagonist, Angiotensin II receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Stockholm South General Hospital |
Swedish Medical Research Council |
Sweden |
2020-04-21 |
2021-02-28 |
2020-002040-22, ISRCTN48734830, RECOVER |
Phase 4 Clinical |
Not yet recruiting |
2 |
10 Months |
750 |
Dr Anders Hedman, Dr Edgren |
2020-07-15 |
| Prospective, multicenter evaluation of psychological distress in obstetric patients during pre and postnatal isolation in inpatient setting in the context of the SARS-CoV-2-pandemic (COVID-19) |
Coronavirus disease 19 infection, Postnatal depression, Psychiatric disorder |
|
|
Female, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Universitätsklinik Freiburg Klinik für Frauenheilkunde |
|
Germany |
2020-04-18 |
|
202/20, DRKS00021247 |
Phase Not Applicable |
Recruiting |
5 |
|
100 |
Carmen Geibler |
2020-07-15 |
| Corona Immunitas: A nationwide program of antibody studies of SARS-CoV-2 in the Swiss population |
Coronavirus disease 19 infection |
|
|
|
Foundation Swiss School of Public Health |
Swiss Federal Office of Public Health |
Switzerland |
2019-03-18 |
2021-12-31 |
Corona Immunitas, ISRCTN18181860 |
Phase Not Applicable |
Recruiting |
8 |
33 Months |
25000 |
Dr Anja Frei, Prof Jan Fehr, Prof Puhan |
2020-07-15 |
| Clinical study to evaluate efficacy and safety of GanjhuVir syrup and tablet in Covid-19 positive patients |
Coronavirus disease 19 infection |
GanjhuVir alone, Standard of Care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Radhika Ayurveda Research and Development |
|
India |
2020-07-10 |
|
CTRI/2020/07/026463 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
15 |
Dr Rajesh Kumar Ganjhu, Mr C Devanpally |
2020-07-15 |
| A study to observe and assess the safety and efficacy of Unani regimen in preventing the progression of severity of asymptomatic mild to moderate symptomatic cases |
Coronavirus disease 19 infection |
Khameera Marvareed alone, Unani Joshanda Decoction alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Central Council for Research in Unani Medicine |
|
India |
2020-07-20 |
|
CTRI/2020/07/026462 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
124 |
Dr Nauman Saleem, Dr Usama Akram, Prof Asim Ali Khan |
2020-07-15 |
| Clinical manifestations in neonates born to Covid 19 positive mothers |
Coronavirus disease 19 infection |
|
|
Newborn Infants (up to 5 months) |
Govt. Medical College Aurangabad |
|
India |
2020-07-25 |
|
CTRI/2020/07/026516 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
50 |
Dr LS Deshmukh, Dr Sukena Susnerwala |
2020-07-16 |
| Randomized, Controlled Trial Of Resveretrol-Copper Or Sodium-Copper-Chlorophyllin Versus Standard Treatment In Mild Covid-19 infection with Cancer Patients |
Coronavirus disease 19 infection |
Resveratrol-Copper alone, sodium copper chlorophyllin alone, standard treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tata Memorial Centre |
|
India |
2020-07-22 |
|
CTRI/2020/07/026515 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
300 |
Pankaj Chaturvedi, VIKRAM GOTA |
2020-07-15 |
| COVID-TEST: COVID-19 Rapid Diagnostic Tests on Blood Drop |
Coronavirus disease 19 infection, Viral pneumonia |
Biosynex rapid blood test alone |
|
|
CMC Ambroise Pare |
|
|
2020-07-15 |
2020-08-15 |
2020/05, COVID-TEST, NCT04467008 |
Phase Not Applicable |
Not yet recruiting |
0 |
1 Month |
113 |
|
2020-07-15 |
| Hemostasis in COVID-19: an Adaptive Clinical Trial |
Coronavirus disease 19 infection |
aspirin alone, enoxaparin sodium alone, thromboprophylaxis institutional protocol alone, unfractionated heparin alone |
Low molecular weight heparin |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo |
|
Brazil |
2020-07-08 |
2021-04-30 |
33788820.9.0000.0068, NCT04466670 |
Phase 3 Clinical |
Recruiting |
1 |
9 Months |
310 |
Cynthia Rotschild, MD, Elbio A D'Amico, MD.PhD, Erica Okazaki, MD, Paula R Villaca, MD.PhD, Tania RF Rocha, MPharm, Vanderson Geraldo Rocha, Vanderson Rocha, MD.PhD, Yeh-Li Ho, MD.PhD |
2020-07-15 |
| Investigation of Safety and Efficacy of CARDIO Softgels in Former Smokers and Asthma Patients With COVID-19 Infection |
Asthma, Coronavirus disease 19 infection, Respiratory disease, Respiratory distress syndrome |
CARDIO alone, standard-of-care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Hofseth Biocare AS |
KGK Science Inc. |
Canada |
2020-08-31 |
2021-08-31 |
20CCHH, NCT04465513 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
100 |
Andrew Charrette, MSc, David Crowley, MD, Malkanthi Evans, PhD |
2020-07-15 |
| COVID-19-HRCT versus Deep Learning Tech |
Coronavirus disease 19 infection, Viral pneumonia |
HRCT Thorax alone |
|
|
Hospital Tunku Azizah |
|
Malaysia |
2020-07-31 |
2020-12-31 |
55342, NMRR-20-1426-55342 |
Phase Not Applicable |
Not yet recruiting |
1 |
5 Months |
35 |
Dr Asiah Kassim, Dr LUI SZE CHIANG |
2020-07-16 |
| Effectiveness of Mouthwashes in Early Reducing the Mouth Viral Load Among COVID-19 Patients |
Coronavirus disease 19 infection |
cetylpyridinium chloride mouthwash alone, hydrogen peroxide mouthwash alone, povidone-iodine mouthwash alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Hamadan University of Medical Sciences |
|
Iran |
2020-07-11 |
|
IR.UMSHA.REC.1399.235, IRCT20170117032025N7 |
Phase 3 Clinical |
Recruiting |
1 |
|
60 |
Dr Ali Heidari, Dr Saeed Bashirian |
2020-07-14 |
| Effect of Tele-Yoga Therapy on Patients With Chronic Musculoskeletal Pain During Covid-19 Lockdown |
Coronavirus disease 19 infection, Musculoskeletal pain |
Tele-yoga therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Aarogyam UK |
NMP Medical Research Institute |
India |
2020-03-30 |
2020-07-06 |
AU/NMP/0921, NCT04466605 |
Phase Not Applicable |
Completed |
1 |
3 Months |
64 |
Abhimanyu Kumar, Bhavna Pandya, Naveen Meghwal, Neha Sharma |
2020-07-20 |
| Hypertonic Saline for COVID-19 Symptoms |
Coronavirus disease 19 infection |
Wearing surgical face mask sprayed with hypertonic saline alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
King Faisal Specialized Hospital & Research Center |
|
Saudi Arabia |
2020-07-01 |
2021-05-31 |
H-01-R-007, NCT04465604, RAC # 2201072 |
Phase Not Applicable |
Recruiting |
1 |
11 Months |
50 |
Ali Alshanqeeti, MD |
2020-07-15 |
| An observational cohort study to evaluate volume and severity of emergency general surgery admissions during the COVID-19 pandemic: is there a 'lockdown' effect? |
Coronavirus disease 19 infection |
|
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
North Tees and Hartlepool NHS Foundation Trust |
|
China |
2020-02-16 |
2020-05-15 |
ChiCTR2000034588 |
Phase Not Applicable |
Completed |
1 |
3 Months |
207 |
Kevin Etherson, Ross McLean |
2020-07-14 |
| Follow-up study on the recovery period of novel coronavirus pneumonia (COVID-19) patients |
Coronavirus disease 19 infection |
Pulmonary rehabilitation training alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Public and Health Clinic Centre of Chengdu |
Sichuan Science and Technology Department Project |
China |
2020-02-16 |
2021-12-31 |
ChiCTR2000034563, K-2020-02 |
Phase Not Applicable |
Recruiting |
1 |
22 Months |
50 |
Dafeng Liu, Lijuan |
2020-07-17 |
| Development of COVID-19 RT-LAMP |
Coronavirus disease 19 infection |
Loop-mediated isothermal amplification (RT-LAMP) assay alone |
|
|
Institute For Medical Research (Inc In Malaysia) |
National Institutes of Health Malaysia |
Malaysia |
2020-09-01 |
2021-12-31 |
55724, NMRR-20-1423-55724 |
Phase Not Applicable |
Status not specified |
1 |
16 Months |
|
Dr FOO PHIAW CHONG |
2020-07-16 |
| Administration of Anti-SARS-CoV-2 Convalescent Plasma in Hospitalized, Non-ICU Patients With COVID-19 |
Coronavirus disease 19 infection, Respiratory disease |
anti-SARS-CoV-2 convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Southern California |
|
US |
2020-08-31 |
2021-12-31 |
HS-20-00516, NCT04467151 |
Phase 2 Clinical |
Not yet recruiting |
1 |
16 Months |
96 |
Diane F McIntee, MS, Jean B Chan, Kashif T Khan, MD, SM |
2020-07-14 |
| Arrhythmic Manifestations and Management Strategies in Hospitalized COVID-19 Patients: Multicenter Registry |
Coronavirus disease 19 infection, Heart arrhythmia |
standard of care treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kansas City Heart Rhythm Research Foundation |
|
US |
2020-07-31 |
2020-07-31 |
KCHRF-COVID-19-0001, NCT04465552 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
750 |
Donita Atkins, RN, BSN, Rakesh Gopinathannair, MD |
2020-07-14 |
| COVID-EP: Registry of the Evolution of Diagnosed and/or Hospitalized Patients for Pulmonary Embolism During the COVID-19 Pandemic |
Coronavirus disease 19 infection, Lung embolism |
ELISA test alone, RT-PCR alone, Rapid diagnostic tests alone, nasopharyngeal sample alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital St. Joseph, Marseille, France |
|
France |
2020-07-01 |
2021-04-30 |
2020-05-01, COVID-EP, NCT04465656 |
Phase Not Applicable |
Not yet recruiting |
1 |
10 Months |
250 |
Cécile Bielmann, Rahmia AHAMADA |
2020-07-14 |
| ODYSSI: Assessment of Olfactory Dysfunction in SARS-CoV-2 (COVID-19) Infection |
Coronavirus disease 19 infection, Olfaction disorder, Respiratory distress syndrome |
University of Pennsylvania Smell Identification Test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cambridge University Hospitals NHS Foundation Trust |
Imperial College Healthcare NHS trust, Royal Cornwall Hospitals Trust |
UK |
2020-07-02 |
2022-01-31 |
NCT04466982, ODYSSI, REC REF: 20/SC/0231 |
Phase Not Applicable |
Recruiting |
3 |
18 Months |
90 |
Brian Fish, FRCS (ORL-HNS), Catherine Rennie, FRCS (ORL-HNS), Ekpemi Irune, Ekpemi Irune, FRCS (ORL-HNS), Gina Townley, Hesham Saleh, FRCS (ORL-HNS), Kristian Hutson, FRCS (ORL-HNS), Neil Tan, FRCS (ORL-HNS), Omolade Awomolo, Rachel Kyd, FRCS (ORL-HNS), Rishi Sharma, FRCS (ORL-HNS) |
2020-07-14 |
| SPARC-1: Pediatric Acute Kidney Injury in COVID-19 |
Coronavirus disease 19 infection, Renal injury |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Children's Healthcare of Atlanta |
Children's of Alabama, Cincinnati Children's Hospital Medical Center, Hospital for Sick Children |
Serbia, Africa, Europe, US, Japan, Australia, Asia, North America, Spain, Israel, UK, Canada |
2020-04-15 |
2021-07-01 |
CHILDRENSHA, NCT04466306, SPARC-1 |
Phase Not Applicable |
Recruiting |
48 |
14 Months |
250 |
Rajit K Basu, MD |
2020-07-14 |
| PREVENT: Low-Dose Radiotherapy For Patients With SARS-COV-2 (COVID-19) Pneumonia |
Coronavirus disease 19 infection, Lung inflammation, Viral pneumonia |
standard best supportive care alone, whole thorax megavoltage radiotherapy (35, 100 cGy) alone |
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ohio State University Comprehensive Cancer Center |
Varian Medical System Inc |
US |
2020-07-01 |
2022-12-31 |
NCT04466683, PREVENT, PREVENT |
Phase 2 Clinical |
Not yet recruiting |
2 |
30 Months |
100 |
Arnab Chakravarti, MD, Kimberly Mahler |
2020-07-14 |
| A TELUS Home Health Monitoring (HHM) trial to test the efficacy of virtual monitoring solutions to care for a large number of patients at one time while in their own homes, and the ability to provide care in rural locations for patients with chronic disease conditions and COVID-19 response |
Coronavirus disease 19 infection |
|
|
|
Alberta Health Services, Alberta Innovates, Canada, Boehringer Ingelheim (Canada) Ltd, TELUS Health |
|
Canada |
|
|
|
Phase Not Applicable |
Status not specified |
2 |
|
|
Andrea Thain Liptak, Dr. Jordan La Rue |
2020-07-13 |
| GSHSOD-COVID: Antioxidant Therapy for COVID-19 Study |
Coronavirus disease 19 infection |
Standard of care alone, Variable regimens including N-acetylcysteine , bovine lactoferrin , immunoglobulins , reduced glutathione , superoxide dismutase |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Obafemi Awolowo University |
Abia State Ministry of Health, Benue State Ministry of Health, Borno State Ministry of Health, Ogun State Ministry of Health, Sokoto State Ministry of Health, University of Calabar Teaching Hospital |
Nigeria |
2020-08-01 |
2020-12-31 |
GSHSOD-COVID, GSHSOD-COVID2020, NCT04466657 |
Phase Not Applicable |
Not yet recruiting |
11 |
5 Months |
90 |
Adeniyi Olagunju, BPharm, MRes, PhD, Audu Onyemocho, MBBS, Bolanle Adefuye, MBBS, Festus Soyinka, MBBS, Franklin Alozie, Gloria B Imhonopi, MBBS, MPH, FMCPH, Ibrahim M Kida, MBBS, Ibrahim M Ngulde, MBChB, Ijeoma Nduka, MBBS, Ofem Enang, MBBS, Patrick Echekwube, MBBS, FMCP, Sirajo Haliru, MBBS, Usman M Bello, MBBS, Zainu Sabitu, MBBS |
2020-07-14 |
| Prophylactic Favipiravir for Healthcare Workers in COVID-19 Pandemic |
Coronavirus disease 19 infection |
favipiravir alone |
RNA polymerase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shaheed Beheshti Medical University |
|
Iran |
2020-03-20 |
|
IR.SBMU.NRITLD.REC.1399.021, IRCT20150107020592N30 |
Phase 3 Clinical |
Recruiting |
1 |
|
30 |
Ali Ziai, Dr Seyyed Mohamadreza Hashemian, Seyed Mohammad Reza Hashemian |
2020-07-14 |
| Non-Inferiority Trial for Detection of nCOVID-19 Through Analysis of Exhaled Breath Aerosols |
Coronavirus disease 19 infection |
Breath Biopsy face masks with removable filters and fitted PVA strip alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Owlstone Nanotech Inc |
Cambridge University Hospitals NHS Foundation Trust |
UK |
2020-07-31 |
2020-12-31 |
COVID-BREATH, NCT04467112 |
Phase Not Applicable |
Not yet recruiting |
1 |
5 Months |
100 |
Alexandra Saedeleer, Stefan Marciniak, amerjit Kang |
2020-07-14 |
| Randomized, Controlled Trial Of Resveretrol-Copper OR Sodium-Copper-Chlorophyllin Versus Standard Treatment In Severe Covid-19 Cancer Patients |
Coronavirus disease 19 infection, Viral pneumonia |
Resveratrol-Copper alone, Standard treatment alone, chlorophyllin alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tata Memorial Hospital |
|
India |
2020-07-22 |
|
CTRI/2020/07/026514 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
200 |
Pankaj Chaturvedi, VIKRAM GOTA |
2020-07-17 |
| Clinical presentation, Management, Treatment and Outcome of COVID patients |
Coronavirus disease 19 infection |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hindu Mission Hospital |
|
India |
2020-07-17 |
|
CTRI/2020/07/026510 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1000 |
Dr D K Sriram, Dr Melvin George |
2020-07-16 |
| Efficacy and Safety of Mucoadhesive Sustained Release, Mucodentol, in Comparison With Hydroxychloroquine to Prevent COVID-19 |
Coronavirus disease 19 infection |
Mucodentol gel alone, Personal protective equipment alone, hydroxychloroquine alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Baqiyatallah University of Medical Sciences |
|
Iran |
2020-07-15 |
2020-12-15 |
IR.BMSU.REC.1399.086, NCT04466280 |
Phase 2 Clinical |
Recruiting |
1 |
5 Months |
180 |
Mohammad Sadegh Bagheri Baghdasht |
2020-07-14 |
| Investigation of Antibody and Immune Responses to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) or COVID-19 Proteins (SARS-CoV-2) |
Coronavirus disease 19 infection |
RT-PCR alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
TMC HealthCare |
INanoBio |
US |
2020-07-31 |
2021-06-30 |
INANO-CV1, NCT04465981 |
Phase Not Applicable |
Recruiting |
1 |
11 Months |
80 |
Natalia Elias Calles, MPH |
2020-07-14 |
| Effect of TOCILIZUMAB (ACTEMRA) on treatment of COVID-19 |
Coronavirus disease 19 infection |
tocilizumab (intravenous), Roche/Chugai alone |
IL-6 receptor antagonist, IL-6 receptor modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tehran University of Medical Sciences |
|
Iran |
2020-04-29 |
|
IR.TUMS.VCR.REC.1399.290, IRCT20081027001411N4 |
Phase 2 Clinical |
Recruiting |
2 |
|
40 |
Ahmadreza Jamshidi, Mahdi Mahmoudi, Maryam Akhtari, Mohammad Reza Salehi, Mona Talaschian |
2020-07-14 |
| INTENSE-COV: Combination Therapies to Reduce Carriage of SARS-Cov-2 and Improve Outcome of COVID-19 in Ivory Coast: a Phase IIb, Randomized Trial |
Coronavirus disease 19 infection, Inflammatory disease, Respiratory disorder |
Variable regimens including atorvastatin (Tahor) , lopinavir + ritonavir , telmisartan |
Angiotensin II receptor antagonist, HIV protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
French National Agency for Research on AIDS and Viral Hepatitis |
Universite de Bordeaux |
|
2020-07-20 |
2020-12-20 |
ANRS COV01 INTENSE COV, INTENSE-COV, NCT04466241 |
Phase 2b Clinical |
Not yet recruiting |
0 |
5 Months |
294 |
Adama Doumbia, MD, Baba Toumani Sidibé, MD, Fabrice Bonnet, M.D., Ph.D., Serge Eholié, M.D., Ph.D. |
2020-07-14 |
| SUN: Sustainable University Life Study |
Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression, Musculoskeletal pain |
SMS messaging alone, focus group interviews alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sophiahemmet University |
Forte, Karolinska Institutet |
Sweden |
2019-08-19 |
2032-01-31 |
FORTE2018-00402, NCT04465435, SUN |
Phase Not Applicable |
Recruiting |
1 |
149 Months |
5000 |
Eva Skillgate, Professor, Ph.D. |
2020-07-14 |
| Coronavirus Disease 2019 (COVID-19) During Pregnancy: Prevalence of Seroconversion, Effect on Maternal and Perinatal Outcomes and Risk of Vertical Transmission |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Chinese University of Hong Kong |
Kwong Wah Hospital, Pamela Youde Nethersole Eastern Hospital, Peking University First Hospital, Princess Margaret Hospital, Queen Elizabeth Hospital, Hong Kong, Queen Mary Hospital, Tuen Mun Hospital, United Christian Hospital, University Hospital of Torrejon |
Spain, China, Hong Kong |
2020-05-01 |
2022-12-31 |
COVID-MAP, NCT04465474 |
Phase Not Applicable |
Recruiting |
10 |
32 Months |
3000 |
Ada WT TSE, MBChB, Annie SY HUI, MBBS, MRCOG, FHKCOG, FHKAM, Chiu Yee Liona Poon, Choi Wah KONG, MBChB, MRCOG, FHKAM, FHKCOG, Chung Nin LEE, MBBS, MMedSc, FRCOG, FHKCOG, Equal L CHEN, Huixia YANG, MD, PhD, Ka Wang CHEUNG, MBBS, MRCOG, FHKCOG, FHKAM, Liona Chiu Yee Poon, MBBS, MRCOG, MD, Liona POON, Maria del Mar GIL, PhD, Nga Yui, Florrie YU, MBChB, MRCOG, FHKAM (O&G), Ngai Man CHAN, MBBS, MSc, Wei Ling Teresa MA, FRCOG, FHKAM, Wing Cheong LEUNG, MBBS, MRCOG, FHKAM, FHKCOG |
2020-07-20 |
| A clinical study of favipiravir in patients with mild and moderate COVID-19 |
Coronavirus disease 19 infection |
favipiravir alone |
RNA polymerase inhibitor |
|
R-Pharm |
|
Russian Federation |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
|
|
2020-07-17 |
| Clinical Study of Recombinant Novel Coronavirus Vaccine |
Coronavirus disease 19 infection |
SARS-CoV-2 protein subunit vaccine (COVID-19), Chongqing Zhifei Biological Products/ Institute of Microbiology, Chinese Academy of Sciences alone |
COVID19 Spike glycoprotein modulator |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Anhui Zhifei Longcom Biopharmaceutical Co Ltd |
|
China |
2020-07-12 |
2021-12-15 |
NCT04466085, NCV-II-HEALTHY |
Phase 2 Clinical |
Recruiting |
1 |
17 Months |
900 |
fan Di, master, fangjun Li, bachelor |
2020-07-20 |
| Safety and Feasibility of Allogenic MSC in the Treatment of COVID-19 |
Coronavirus disease 19 infection |
mesenchymal stromal cells alone |
|
|
Hospital de Clinicas de Porto Alegre |
|
Brazil |
2020-07-25 |
2020-12-30 |
20200148, NCT04467047 |
Phase 1 Clinical |
Not yet recruiting |
1 |
5 Months |
10 |
Annelise Pezzi, PhD, Lucia Silla, MD, PhD |
2020-07-14 |
| A trial to evaluate IBIO-201 for the treatment of COVID-19 |
Coronavirus disease 19 infection |
IBIO-201 alone |
COVID19 Spike glycoprotein modulator |
|
iBio Inc |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-07-14 |
| COALITION-V: Randomized, Placebo-controlled Trial of Hydroxychloroquine in Outpatient Cases With Coronavirus Disease 2019 (COVID-19) |
Coronavirus disease 19 infection, Respiratory disease |
hydroxychloroquine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Alemão Oswaldo Cruz |
Brazilian Research In Intensive Care Network, EMS SA, Hospital Of Syrian Lebanese Itatiba S/C Ltd, Hospital do Coracao, Instituto de Educação e Pesquisa do Hospital Moinhos de Vento, Sociedade Beneficente Israelita Brasileira Hospital Albert Einsten |
Brazil |
2020-05-12 |
2020-12-30 |
30415320.8.1001.0070, COALITION-V, NCT04466540 |
Phase 4 Clinical |
Recruiting |
69 |
7 Months |
1300 |
Adrian Kormann, MD, Agnaldo Piscopo, MD, Alexandre Naime Barbosa, MD, Alexandre Pereira Tognon, MD, Alexandre Vargas, MD, Alexandre ZIli, MD, Alexandre Zili, MD, Aline Thomaz Soares, MD, Amanda MR de Oliveira, MD, André Scazufka Ribeiro, MD, Antoônio Carlos da Silva, MD, Antônio Carlos da Silva, MD, Audes Feitosa, MD, Carlos Costa Magalhães, MD, Carlos Humberto Miguel, MD, Conrado Hoffmann, MD, Cristina Prata Amendola, MD, César Minelli, MD, Danilo Lins Cordeiro Campos, MD, Dayane Vilanova, Edgar Ferreira Santos, MD, Emílio César Zilli, MD, Felipe Dal Pizzol, MD, Fernanda Quintino, MD, Frederico Dall'Orto, MD, Frederico Thadeu Assis Figueiredo Campos, MD, Frederido Dall'Orto, MD, Germano Emílio, MD, Haliton Alves de Oliveira Junior, Ph.D, Jorge Luiz da Rocha Paranhos, MD, José Joaquim Fernandes Raposo Filho, MD, Jônatas Melo Neto, MD, Karen Mirna Loro Morejon, MD, Kengi Itinose, MD, Leandro Echenique, MD, Leila Azavedo, MD, Leila Azevedo, MD, Letícia Santos Bicudo, MD, Loren Brito, MD, Luciano César Pontes de Azevedo, MD, Luiz Eduardo Ritt, MD, Luiz da Rocha Paranhos, MD, Marco Antônio Mota Gomes, MD, Mauro Hernandes, MD, Meton Soares de Alencar Filho, MD, Miquéias Martins Lima Silva, MD, Márcia Lílian Sampaio e Sampaio Sá, MD, Márcio Andrade Martins, MD, Otávio Berwanger, MD, Otávio Gebara, MD, Paulo Ernesto Leães, MD, Paulo Rizzo Genestreti, MD, Paulo Roberto Abrão Ferreira, MD, Pedro Gabriel Melo de Barros e Silva, MD, Priscila Freitas, MD, Raphael Luzório Fernandes, MD, Ricardo D'Oliveira Vieira, MD, Ricardo De Gasperi, MD, Ricardo de Gasperi, MD, Robeeto Luiz Kaiser Junior, MD, Roberto Luiz Kaiser Junior, MD, Roberto Ranza, MD, Rodrigo Molina, MD, Régis Goulart, MD, Sandro Rodrigues Batista, MD, Sidiner Mesquita Vaz, MD, Sérgio Seiji Yamada, MD, Sérgio Tavares Montenegro, MD, Thales Aníbal Leite Barros Agostinho, MD, Valéria Fontanelli Angelim Pereira, MD, Vicente Lopes, MD, Vinícius Ortigosa Nogueira, MD, Wolney de Andrade Martins, MD, Álvaro Avezum, Ph.D |
2020-07-14 |
| Perceptions of Undergraduate Students and Teaching Staff on Online Teaching |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Misr International University |
|
Egypt |
2020-07-15 |
2021-11-01 |
NCT04466371, PUB 1114005 |
Phase Not Applicable |
Not yet recruiting |
1 |
15 Months |
9209 |
|
2020-07-14 |
| Multiple Dosing of Mesenchymal Stromal Cells in Patients With ARDS (COVID-19) |
Coronavirus disease 19 infection, Respiratory distress syndrome |
mesenchymal stromal cells alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Masonic Cancer Center |
|
US |
2020-08-01 |
2021-12-01 |
2020LS075, MT2020-12, NCT04466098 |
Phase 2a Clinical |
Not yet recruiting |
2 |
16 Months |
30 |
David Ingbar, MD, Luis Ortiz, MD |
2020-07-14 |
| Dual Therapy With Interferon Beta-1b and Clofazimine for COVID-19 |
Coronavirus disease 19 infection |
standard care alone, clofazimine plus interferon beta-1b |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The University of Hong Kong |
|
Hong Kong |
2020-07-14 |
2021-09-30 |
NCT04465695, UW 20-463 |
Phase 2 Clinical |
Recruiting |
1 |
14 Months |
81 |
Ivan FN Hung, MD FRCP, Kelvin KW To, MD FRCPath |
2020-07-16 |
| Cross-sectional Study of COVID-19 Infection in Hospital Health Personnel |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fundacio Lluita Contra La Sida |
|
Spain |
2020-05-26 |
2020-06-30 |
COVID-HOSP, NCT04466462 |
Phase Not Applicable |
Completed |
2 |
1 Month |
1000 |
|
2020-07-14 |
| Evaluation of ivermectin effects on COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
ivermectin alone, standard of care alone |
Chloride channel modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kermanshah University of Medical Sciences |
|
Iran |
2020-08-22 |
|
IR.KUMS.REC.1399.289, IRCT20190624043993N2 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
50 |
Dr. Farid Najafi, Foroud Shahbazi, Maria Shirvani |
2020-07-14 |
| COVID-19: A Prevalence Study of Two ART Centers After the Pandemic Lockdown in the USA (COVID-19 Free Clinics) |
Coronavirus disease 19 infection |
ELISA alone, RT-PCR alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Igenomix Spain |
|
US |
2020-06-08 |
2020-09-30 |
20201490, IGX2-COV-JC-20-04, NCT04466644 |
Phase Not Applicable |
Recruiting |
2 |
3 Months |
400 |
Carlos Gomez, Bsc, MSc, Carlos Simon, MD, PhD, Denny Sakkas, PhD, Juliana Cuzzi, PhD, Russell A Foulk, MD |
2020-07-14 |
| The effect of diet based on traditional medicine on COVID-19 |
Coronavirus disease 19 infection |
diet containing pomegranate juice and sumac alone, routine treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Mashhad University of Medical Sciences |
|
Iran |
2020-08-22 |
|
IR.MUMS.REC.1399.313, IRCT20190406043175N3 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
80 |
Hassan Rakhshandeh, Mohsen Tafaghodi |
2020-07-14 |
| ERCO-Park: Evaluation of the Containment Impact Linked to the COVID-19 Pandemic in a Population of Parkinson Patients |
Coronavirus disease 19 infection, Parkinsons disease |
|
|
|
Centre Hospitalier Universitaire de Toulouse |
|
France |
2020-07-02 |
2020-12-18 |
ERCO-Park, NCT04466839, RC31/20/0193 |
Phase Not Applicable |
Not yet recruiting |
8 |
5 Months |
400 |
Anne Doé de Maindreville, Céline Bergot, David Maltête, Delphine Vernet, Fabienne ORY MAGNE, Fréderique Fluchere, Grabli David, Luc Defevbre, Marie De Verdal, Matthieu Bereau, Nicolas Carriere, Tatiana Witjas |
2020-07-14 |
| COVID-19 Outbreak in Emergency Department |
Coronavirus disease 19 infection |
non-pharmaceutical interventions alone |
|
|
Shonan Kamakura General Hospital |
|
Japan |
2015-01-01 |
|
UMIN000041073 |
Phase Not Applicable |
Recruiting |
1 |
|
100000 |
Hiroshi Yamagami, Ichiro Sekine |
2020-07-14 |
| Evaluating Adaptive Dispenser Initiation Protocols for MySafeRx During Post-detox Buprenorphine Treatment- a Pilot Study |
Coronavirus disease 19 infection, Opiate dependence |
MySafeRx Inspire Plus alone, buprenorphine + naloxone alone, coaching alone, manual lockbox alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
University of South Florida |
Cambridge Health Alliance |
US |
2020-06-24 |
2021-02-01 |
NCT04449744, PRO00038163 - PILOT, R01CE003039 |
Phase 2 Clinical |
Not yet recruiting |
2 |
7 Months |
30 |
Cassandra Harding, MPH, Kathleen Moore, PhD, Melissa Carlson, BS, Zev Schuman-Olivier, MD |
2020-07-13 |
| MONITOR: 'NORPLASMA' COVID-19 Convalescent Plasma Treatment Monitoring Study |
Coronavirus disease 19 infection |
COVID-19 convalescent plasma alone, NORPLASMA MONITOR alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Oslo University Hospital |
|
Norway |
2020-07-06 |
2025-05-31 |
148622, MONITOR, NCT04463823 |
Phase Not Applicable |
Not yet recruiting |
1 |
58 Months |
500 |
Lise Sofie Haug Nissen-Meyer, Ph.D, Lise Sofie Haug Nissen-Meyer, Ph.D., Tor Audun Hervig, Ph.D |
2020-07-13 |
| Desidustat in the Management of COVID-19 Patients |
Coronavirus disease 19 infection |
desidustat alone, standard of care alone |
HIF prolyl hydroxylase-2 inhibitor, Prolyl hydroxylase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Zydus Cadila Healthcare Ltd |
|
Mexico |
2020-07-25 |
2021-01-30 |
DESI.20.004, NCT04463602 |
Phase 2b Clinical |
Not yet recruiting |
1 |
6 Months |
24 |
Dr Deven Parmar, MD, Dr Richa Vellanki, Dr. Jesus Zacarias Villareal Martinez |
2020-07-20 |
| Avi-Mild: Favipiravir Therapy in Adults With Mild COVID-19 |
Coronavirus disease 19 infection |
favipiravir alone |
RNA polymerase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
King Abdullah International Medical Research Center |
Ministry of Health Saudi Arabia |
|
2020-07-31 |
2021-06-30 |
Avi-Mild, NCT04464408, RC 20/220/R |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
0 |
11 Months |
576 |
Majed Al Jeraisy, Mohammad Bosaeed |
2020-07-13 |
| Study of CPI-006 as Immunotherapy for Hospitalized COVID-19 Patients |
Coronavirus disease 19 infection |
CPI-006 alone |
CD73 antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Corvus Pharmaceuticals Inc |
|
US |
2020-07-01 |
2021-08-31 |
CPI-006-002, NCT04464395 |
Phase 1 Clinical |
Recruiting |
2 |
14 Months |
30 |
D Strahs, Dana Ostrowski, Gerard J Criner, MD, Joshua Brody, MD, S. Mahabhashyam, MD, Temple Lung Center |
2020-07-14 |
| COBETOX: Effects of COVID-19 Infection on Beta-cell Function in Euglycemic Patients |
Coronavirus disease 19 infection |
arginine hydrochloride alone, stimulation test alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universita degli Studi di Milano |
Ospedale Luigi Sacco Azienda Ospedaliera Polo Universitario |
Italy |
2020-06-30 |
2021-06-30 |
6/2020, COBETOX, NCT04463849 |
Phase 2 Clinical |
Recruiting |
1 |
12 Months |
24 |
Paolo Fiorina, MD, Paolo Fiorina, MD, PhD, Teresa Letizia, Dr. |
2020-07-13 |
| MUCONFIN: Impacts of the Covid-19 Epidemic and Associated Lockdown Measures on the Management, Health and Behaviors of Cystic Fibrosis Patients During the 2020 Epidemic |
Coronavirus disease 19 infection, Cystic fibrosis |
|
|
Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Intercommunal Creteil |
|
France |
2020-05-15 |
2021-06-30 |
MUCONFIN, MUCONFIN, NCT04463628 |
Phase Not Applicable |
Recruiting |
3 |
13 Months |
1200 |
Dominique GRENET, MD, PhD, Harriet CORVOL, MD, PhD, Ralph EPAUD, MD PhD, Ralph EPAUD, MD, PhD |
2020-07-14 |
| Efficacy and Safety Study of Nitazoxanide (NTX) in the Treatment of Patients With SARS-CoV-2 Virus Infection (COVID-19) |
Coronavirus disease 19 infection |
nitazoxanide alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Laboratorios Roemmers S.A.I.C.F. |
|
Argentina |
2020-06-26 |
2020-10-26 |
NCT04463264, NTZ-COVID ARG1 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
4 Months |
135 |
Diego Enriquez, MD, Marcelo Silva, MD |
2020-07-16 |
| Characteristics of Critically Ill COVID 19 Patients |
Coronavirus disease 19 infection |
|
|
|
Assiut University |
|
Egypt |
2020-07-08 |
2020-08-10 |
NCT04465058, YTE |
Phase Not Applicable |
Recruiting |
1 |
1 Month |
50 |
Rasha Hamed, lecturer of anaesthesia, rasha hamed, MD |
2020-07-13 |
| A phase IIb, proof-of-efficacy study of OVX-836 for the potential prevention of COVID-19 infection |
Coronavirus disease 19 infection |
OVX-836 alone |
Nucleoprotein modulator |
|
Osivax |
|
|
|
|
|
Phase 2b Clinical |
Planned |
0 |
|
3500 |
|
2020-07-10 |
| A Study to Evaluate the Safety, Pharmacokinetics (PK) and Efficacy of TAK-671 for the Treatment of Coronavirus Disease (COVID) 2019 in Adults |
Coronavirus disease 19 infection, Respiratory disease |
TAK-671 alone, standard of care alone |
Trypsin inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Takeda Pharmaceutical Co Ltd |
|
US |
2020-07-08 |
2020-08-28 |
NCT04464460, TAK-671-1501, U1111-1252-9426 |
Phase 1b Clinical |
Not yet recruiting |
1 |
1 Month |
40 |
Medical Director, Takeda Study Registration Call Center |
2020-07-13 |
| ImmuneSense Lyme Study |
Anaplasma infection, Babesia infection, Chronic fatigue syndrome, Coronavirus disease 19 infection, Cytomegalovirus infection, Ehrlichia infection, Epstein Barr virus infection, Influenza virus infection, Lyme disease, Multiple sclerosis, Rheumatoid arthritis, Rocky mountain spotted fever, Systemic lupus erythematosus, Treponema pallidum infection |
immunoSEQ Dx test alone |
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Adaptive Biotechnologies Corp |
IQVIA RDS Pty Ltd |
|
2020-06-25 |
2021-12-30 |
NCT04422314, PRO-00717 |
Phase Not Applicable |
Not yet recruiting |
0 |
18 Months |
990 |
Emily Svejnoha, Ms., Jennifer Dines, MD, Thomas Manley, MD |
2020-07-13 |
| COVID19 Severity Prediction and Health Services Research Evaluation |
Coronavirus disease 19 infection, Respiratory distress syndrome, Sepsis, Septic shock |
|
|
|
Hospital Galdakao-Usansolo |
Biocruces Bizkaia Health Reseach Institute, Hospital Costa del Sol, Hospital Universitario Araba(Spain), Hospital Universitario Donostia, Hospital de Basurto, Hospital del Mar, Instituto de Salud Carlos III, University Hospital of the Nuestra Señora de Candelaria |
Spain |
2020-06-01 |
2021-12-31 |
COVID19_0459, NCT04463706 |
Phase Not Applicable |
Recruiting |
1 |
19 Months |
20000 |
Adolfo Muñoz, PhD, Iñigo Gorostiza, PhD, Lilisbeth Perestelo, PhD, Maximino Redondo, PhD, Milagros Iriberri, PhD, Naiara Parraza, PhD, Oier Ateka, PhD, Susana Garcia-Gutierrez, PhD, Susana García-Gutierrez, MD, PhD, Susana García-Gutierrez, PhD, Xavier Castells, MD, PhD |
2020-07-16 |
| Air Pollution and COVID-19 Mortality in Geriatric Patients: a Multicenter Study |
Coronavirus disease 19 infection |
|
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hopitaux Universitaires de Strasbourg |
|
Belgium, France |
2020-06-04 |
2020-09-04 |
7922, NCT04463862 |
Phase Not Applicable |
Recruiting |
11 |
3 Months |
250 |
Bertrand FOUGERE, MD, Claire ROUBAUD BAUDRON, MD, Cédric ANNWEILER, MD, Delphine BETRO, MD, Frédéric BLANC, MD, Georges KALTENBACH, MD, Jean-Baptiste BEUSCART, MD, Laure DE DECKER, MD, Matthieu LILAMAND, MD, Natahlie COMPTE, MD, Nathalie COMPTE, MD, Rachid MAHMOUDI, MD, Rachide MAHMOUDI, MD, Romain DECOURS, MD, Thomas BOURDREL, MD, Thomas VOGEL, MD |
2020-07-13 |
| Coropreg: Covid-19 in Pregnancy: a French Population-based Cohort of Women and Newborns |
Coronavirus disease 19 infection |
|
|
Female |
Assistance Publique Hopitaux de Paris |
INSERM, Epopé team |
France |
2020-05-11 |
2022-10-31 |
APHP200513, Coropreg, NCT04463758 |
Phase Not Applicable |
Recruiting |
1 |
29 Months |
3060 |
Catherine Deneux-Tharaux, MD, PhD, Jean-Marc Treluyer, M.D., PhD, Laurence Lecomte, PhD, Pierre Yv Ancel, MD, PhD |
2020-07-13 |
| Mavrilimumab to Reduce Progression of Acute Respiratory Failure in COVID-19 Pneumonia and Systemic Hyper-inflammation |
Coronavirus disease 19 infection, Hypoxia, Inflammatory disease, Respiratory failure, Viral pneumonia |
mavrilimumab alone |
C-reactive protein inhibitor, Chemokine CC22 ligand inhibitor, GM-CSF receptor antagonist, Hemoglobin scavenger receptor antagonist, Metalloprotease-1 inhibitor, Metalloprotease-3 inhibitor, Small inducible cytokine A17 ligand inhibitor, VEGF gene inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Virginia Commonwealth University |
Kiniksa Pharmaceuticals Ltd |
US |
2020-08-31 |
2021-08-31 |
HM20019145, NCT04337216, NCT04463004 |
Phase 2 Clinical |
Recruiting |
1 |
12 Months |
60 |
Antonio Abbate, MD, PhD |
2020-07-14 |
| A trial to evaluate COVID-HIG in a post-exposure prophylaxis study in individuals at high risk of exposure to COVID-19, such as front-line health care workers and military personnel and other high-risk populations |
Coronavirus disease 19 infection |
COVID-HIG alone |
|
|
Emergent BioSolutions Inc, Mount Sinai Health System, National Institute of Allergy and Infectious Diseases |
|
US |
|
|
|
Phase Not Applicable |
Planned |
1 |
|
|
|
2020-07-10 |
| A phase II/III clinical trial of NVX‑CoV2373 for the potential prevention of COVID-19 infection |
Coronavirus disease 19 infection |
NVX‑CoV2373 alone |
|
|
Novavax Inc |
|
|
|
|
|
Phase 2/Phase 3 Clinical |
Planned |
0 |
|
|
|
2020-07-10 |
| A phase II clinical trial of TXA-127 in hospitalized COVID-19 patients who are not in the Intensive Care Unit (ICU) |
Coronavirus disease 19 infection |
TXA-127 alone |
Angiotensin II receptor modulator |
|
Constant Therapeutics LLC |
|
Italy, US, Israel |
|
|
|
Phase 2 Clinical |
Planned |
3 |
|
|
|
2020-07-10 |
| Safety and Efficacy of PHR160 Spray on the Outcomes of Patients With COVID-19 |
Coronavirus disease 19 infection, Dyspnea |
Variable regimens including PHR160 spray , azithromycin , hydroxychloroquine , naproxen |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Baqiyatallah University of Medical Sciences |
|
Iran |
2020-07-15 |
2020-12-15 |
IR.BMSU.REC.1399.176, NCT04463420 |
Phase 2 Clinical |
Recruiting |
1 |
5 Months |
224 |
Mohammad Sadegh Bagheri Baghdasht |
2020-07-13 |
| ASD Telehealth for Distress Related to COVID-19 |
Acute stress disorder, Coronavirus disease 19 infection |
Emotional Support Plan alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Rutgers University |
|
US |
2020-09-01 |
2021-03-31 |
NCT04460677, PRO2020001593 |
Phase Not Applicable |
Not yet recruiting |
1 |
7 Months |
80 |
Evan M. Kleiman, Vanessa H Bal, Vanessa H Bal, Ph.D. |
2020-07-20 |
| Emergency Department (ED) Self-Monitoring Pilot COVID-19 |
Anxiety disorder, Coronavirus disease 19 infection |
CovidX application alone, pulse oximeter alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Michigan |
Vironix LLC |
US |
2020-07-31 |
2021-04-30 |
HUM00181946, NCT04462783 |
Phase Not Applicable |
Not yet recruiting |
1 |
9 Months |
200 |
Kathleen Li, MD |
2020-07-13 |
| Remote COVID-19 Symptom Tracking for Cancer Patients at Home During the Pandemic |
Cancer, Coronavirus disease 19 infection |
SCH Intervention alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Utah |
|
US |
2020-04-21 |
2021-05-31 |
IRB_00131892, NCT04464486 |
Phase Not Applicable |
Recruiting |
1 |
13 Months |
300 |
Kathleen Mooney, PhD |
2020-07-13 |
| Psychological Intervention for Parent-child Relationship and Couple Relationship Under COVID-19 in China |
Coronavirus disease 19 infection |
Cognitive and behavioral intervention alone, Problem-solving and relationship improvement intervention alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Beijing Normal University |
|
China |
2020-02-01 |
2022-01-31 |
BNULXY, NCT04463433 |
Phase Not Applicable |
Recruiting |
1 |
24 Months |
300 |
Xiuyun Lin, Xiuyun Lin, professor |
2020-07-20 |
| Characteristics and Outcomes of Patients Admitted to Swedish Intensive Care Units for COVID-19 |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital, Linkoeping |
Region Ostergotland |
Sweden |
2020-03-06 |
2020-05-06 |
NCT04462393, SWECOVID |
Phase Not Applicable |
Completed |
1 |
2 Months |
1563 |
Michelle Chew |
2020-07-14 |
| A clinical trial to identify the association of COVID-19 susceptibility near the IVNS1ABP gene |
Coronavirus disease 19 infection |
|
|
|
Ancestry |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
600000 |
|
2020-07-16 |
| A Validation Study of COVID-19 At-Home Saliva Test by Phosphorus |
Coronavirus disease 19 infection |
saliva-based COVID-19 at-home viral test, Phosphorus Inc alone |
|
|
Care Access Research |
Phosphorus Inc |
US |
|
|
|
Phase Not Applicable |
Not yet recruiting |
1 |
|
|
|
2020-07-10 |
| Novel Corona Virus-2019-nCov vaccine by intradermal route in healthy subjects |
Coronavirus disease 19 infection |
ZyCoV-D alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Zydus Cadila Healthcare Ltd |
|
India |
2020-07-13 |
|
CTRI/2020/07/026352, NCOV 1002 |
Phase 1/Phase 2 Clinical |
Recruiting |
1 |
|
1048 |
Dr Kevinkumar Kansagra, Dr Ravindra Mittal, Dr Taufik Momin |
2020-07-17 |
| Efficacy and Safety of Sirolimus in COVID-19 Infection |
Coronavirus disease 19 infection, Leukopenia, Lymphocytopenia, Viral pneumonia |
sirolimus alone, standard of care alone |
mTOR inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Alexandria |
|
Egypt |
2020-07-25 |
2020-10-30 |
NCT04461340, SIROLIMUS IN COVID 19 |
Phase 2 Clinical |
Not yet recruiting |
2 |
3 Months |
40 |
Ayman I Baess, MD, Heba M El weshahi, MD, Mohamed Mamdouh Elsayed, MD, Nermine H Zakaria, MD |
2020-07-14 |
| COVID-19 Convalescent Plasma as Prevention and Treatment for Children With Underlying Medical Conditions |
Congenital heart defect, Coronavirus disease 19 infection, Lung disease, Respiratory failure |
anti-SARS-CoV-2 human convalescent plasma alone |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
University of California Los Angeles |
|
US |
2020-08-31 |
2024-12-31 |
IRB#20-001263, NCT04462848 |
Phase 1 Clinical |
Not yet recruiting |
1 |
52 Months |
30 |
Jaime G Deville, M.D., Michele F Carter, R.N. |
2020-07-14 |
| A phase II clinical trial of GP-1681 for the potential treatment of COVID-19 and the resulting cytokine storm |
Coronavirus disease 19 infection |
esuberaprost sodium (COVID-19-related hypercytokinemia), CytoAgents alone |
Cytokine receptor antagonist, Unspecified GPCR agonist |
|
CytoAgents Inc |
|
|
|
|
|
Phase 2 Clinical |
Planned |
0 |
|
|
|
2020-07-10 |
| A phase I clinical trial of GP-1681 for the potential treatment of COVID-19 and the resulting cytokine storm |
Coronavirus disease 19 infection |
esuberaprost sodium (COVID-19-related hypercytokinemia), CytoAgents alone |
Cytokine receptor antagonist, Unspecified GPCR agonist |
|
CytoAgents Inc |
|
|
|
|
|
Phase 1 Clinical |
Planned |
0 |
|
|
|
2020-07-10 |
| NCOVIP: Northeast COVID-19 and Pregnancy Study Group |
Birth complication, Coronavirus disease 19 infection, Pregnancy disorder |
RT-PCR alone, rapid test alone |
|
Female |
Instituto Materno Infantil Prof. Fernando Figueira |
|
Brazil |
2020-07-01 |
2022-12-20 |
NCOVIP, NCOVIP, NCT04462367 |
Phase Not Applicable |
Not yet recruiting |
1 |
29 Months |
180 |
LEILA KATZ, MD, PhD, MELANIA M AMORIM, MD, PhD |
2020-07-15 |
| NAT-COV-SURV: National Covid-19 Surveillance Physicians |
Coronavirus disease 19 infection |
SARS-CoV2 antibody test alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Heinrich Heine Universitat Dusseldorf |
Arbeitsgemeinschaft Intensivmedizin e.V |
Germany |
2020-06-01 |
2020-09-30 |
2020_2, NAT-COV-SURV, NCT04459312 |
Phase Not Applicable |
Recruiting |
1 |
4 Months |
600 |
Detlef Kindgen-Milles, Prof. |
2020-07-14 |
| TOF-COVID: Sparing in Neuromuscular Blockade in COVID 19 ICU |
Coronavirus disease 19 infection |
Mechanical ventilation alone, Neuromuscular blockade agents infusion alone, Neuromuscular blockade monitor alone, TOF protocol alone, atracurium plus cisatracurium besilate |
Nicotinic acetylcholine receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospices Civils De Lyon |
|
France |
2020-06-01 |
2020-06-01 |
2020_TOF-COVID, NCT04459533, TOF-COVID |
Phase Not Applicable |
Completed |
1 |
|
250 |
|
2020-07-10 |
| A pivotal, phase III clinical trial to evaluate the safety and efficacy of NVX-CoV2373 in healthy subjects |
Coronavirus disease 19 infection |
NVX-CoV2373 alone |
COVID19 Spike glycoprotein modulator |
Healthy volunteers accepted |
Novavax Inc |
|
|
|
|
|
Phase 3 Clinical |
Planned |
0 |
|
30000 |
|
2020-07-09 |
| IL-12RB and TNF-alpha Gene Polymorphism and Susceptibility and Progress of Covid-19 SARS-CoV-2: A Case-Control Study |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assiut University |
|
Egypt |
2020-06-16 |
2020-07-30 |
ASSIUTU15, NCT04462120 |
Phase Not Applicable |
No longer recruiting |
2 |
1 Month |
100 |
Aliae AR Mohamed Hussein |
2020-07-10 |
| A clinical trial of IRL-201104 for the potential treatment of COVID-19 related Acute Respiratory Distress Syndrome (ARDS) |
Coronavirus disease 19 infection, Respiratory distress syndrome |
IRL-201104 alone |
Chaperonin stimulator |
|
DynPort Vaccine Company LLC, Immune Regulation Ltd |
|
US |
|
|
|
Phase Not Applicable |
Planned |
1 |
|
|
|
2020-07-09 |
| Worldwide Trends on COVID-19 Research After the Declaration of COVID-19 Pandemic |
Coronavirus disease 19 infection |
Variable regimens including Convalescent plasma , DAS-181 , hydroxychloroquine , interferon beta-1a , ivermectin |
Chloride channel modulator, Exo-alpha sialidase modulator, Muscarinic receptor antagonist |
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Qassim University |
|
Saudi Arabia |
2020-07-25 |
2020-09-20 |
COAHS, NCT04460547 |
Phase Not Applicable |
Not yet recruiting |
1 |
1 Month |
200 |
Dr Shiva Shankar Bugude |
2020-07-13 |
| CoviDiagMS: SARS-CoV2 (COVID-19) Diagnosis in Human Saliva by MALDI-TOF MS Profiling |
Coronavirus disease 19 infection |
MALDI-TOF MS profiling alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Direction Centrale du Service de Sante des Armees |
|
|
2020-08-31 |
2022-08-31 |
2020-COVID19-15, CoviDiagMS, NCT04460638 |
Phase Not Applicable |
Not yet recruiting |
0 |
24 Months |
600 |
Emilie JAVELLE, MD, Lionel ALMERAS, PhD |
2020-07-11 |
| Identification Of Ace2 And Tmprss2 Polymorphisms In Malaysian Covid-19 Patients |
Coronavirus disease 19 infection |
|
|
|
National Institutes of Health Malaysia |
Ministry of Health, Malaysia |
Malaysia |
2020-08-01 |
2021-12-31 |
55175, NMRR-20-1406-55175 |
Phase Not Applicable |
Status not specified |
1 |
17 Months |
|
ZARINA BINTI MOHD ZAWAWI |
2020-07-10 |
| REEAP COVID-19 |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Malaysia Ministry of Higher Education |
|
Malaysia |
2020-08-03 |
2020-12-31 |
55258, NMRR-20-1393-55258 |
Phase Not Applicable |
Status not specified |
17 |
4 Months |
|
Dr Valerie Shang Chui Moi |
2020-07-10 |
| Reduction of COVID 19 Transmission to Health Care Professionals |
Coronavirus disease 19 infection |
Blood group determination alone, Probactiol Plus alone, gel agglutination technique alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Brugmann University Hospital |
|
Belgium |
2020-04-14 |
2020-12-31 |
CHUB-BDS-COVID19, NCT04462627 |
Phase Not Applicable |
Recruiting |
1 |
8 Months |
500 |
Francis Corazza, MD, Hanane El Kenz, MD |
2020-07-10 |
| Lanadelumab in Participants Hospitalized With COVID-19 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
lanadelumab alone |
Plasma kallikrein inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Takeda Pharmaceutical Co Ltd |
Takeda Development Center Americas, Inc |
|
2020-07-19 |
2020-09-30 |
NCT04460105, TAK-743-1002 |
Phase 1b Clinical |
Not yet recruiting |
0 |
2 Months |
24 |
Study Director, Takeda Development Center Americas (TDCA) Contact |
2020-07-10 |
| Prevention, Efficacy and Safety of BCG Vaccine in COVID-19 Among Healthcare Workers |
Coronavirus disease 19 infection |
BCG vaccine alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Universitario Dr. Jose E. Gonzalez |
|
Mexico |
2020-07-06 |
2021-01-01 |
EN20-00011, NCT04461379 |
Phase 3 Clinical |
Not yet recruiting |
1 |
5 Months |
908 |
René Rodríguez- Gutiérrez, Dr. MSc., René Rodríguez-Gutiérrez, René Rodríguez-Gutiérrez, Dr.MSc. |
2020-07-15 |
| A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Orally Inhaled Aerosolized Hydroxychloroquine Sulfate in Healthy Adult Volunteers |
Coronavirus disease 19 infection |
hydroxychloroquine sulfate alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Pulmoquine Therapeutics, Inc |
Rockefeller University |
US |
2020-06-25 |
2020-09-15 |
NCT04461353, PUL-01 |
Phase 1 Clinical |
Recruiting |
1 |
2 Months |
16 |
Ohad S Bentur, MD, MHA, Robert S Hillman, PhD |
2020-07-14 |
| A trial to evaluate Clungene SARS-CoV-2 Virus (COVID-19) IgG/IgM Rapid Test Cassette to reveal the presence of COVID-19 antibodies |
Coronavirus disease 19 infection |
Clungene SARS-CoV-2 Virus (COVID-19) IgG/IgM Rapid Test Cassette alone |
|
|
Proven Pharmaceuticals LLC |
|
US |
|
|
|
Phase Not Applicable |
Planned |
1 |
|
|
|
2020-07-09 |
| ONCOVID-AURA: Excess Risk of Morbi-mortality Due to COVID-19 in Patients With Cancer |
Coronavirus disease 19 infection, Hematological neoplasm, Solid tumor |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospices Civils De Lyon |
|
France |
2020-06-15 |
2021-02-15 |
69HCL20_0509, NCT04457570, ONCOVID-AURA |
Phase Not Applicable |
Recruiting |
5 |
8 Months |
600 |
BAY Jacques Olivier, MD, Botelho-Nevers Elisabeth, PR, CALATTINI Sarah, FOURNEL Pierre, MD, PEROL David, Pr, PERRON Julien, MD |
2020-07-10 |
| Psychological Preparedness towards Novel Coronavirus (COVID-19) among Old Age Home Staff - an online survey |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Chinese University of Hong Kong |
|
Hong Kong |
2020-07-08 |
2021-07-07 |
ChiCTR2000034537 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
500 |
Allen Ting Chun LEE, Linda Chiu Wa LAM |
2020-07-10 |
| Covid19TmeSer: Forecast Number of Covid-19 Cases Worldwide |
Coronavirus disease 19 infection |
ARIMA model buliding alone, ARIMA model validation alone, Hyndman-Khandakar algorithm alone |
|
|
Izmir Ataturk Training and Research Hospital |
|
Turkey |
2019-12-31 |
2020-06-20 |
Covid19TmeSer, NCT04460274, TURKISHMOHITH-TIMESERIES |
Phase Not Applicable |
Completed |
1 |
5 Months |
7882471 |
Serhat Akay, Principal Investigator |
2020-07-18 |
| Hidden COVID-19 infection in Hong Kong |
Coronavirus disease 19 infection |
|
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Health and Health Services Research Fund |
|
Hong Kong |
2020-05-15 |
2021-05-14 |
ChiCTR2000034522 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
3000 |
Prof. Paul KS Chan |
2020-07-10 |
| Effect of Ayurveda medicinein Covid-19 mild symptoms |
Coronavirus disease 19 infection |
Variable regimens including AYUSH 64 , Dashamula Kwatha , Pathyadi Kwatha , Sansamani Vati , Trikatu Churna , Yastimadhu Ghanavati |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Ayush Govt of Gujarat |
|
India |
2020-07-15 |
|
CTRI/2020/07/026433 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
25 |
Vd Falgun Patel, Vd Shital Bhagiya, Vd Surendra Soni, VdDilip Jani |
2020-07-10 |
| DASS COVID-19: DASS COVID-19 |
Coronavirus disease 19 infection |
|
|
|
Muar Hospital |
|
Malaysia |
2020-07-05 |
2020-09-30 |
55600, DASS COVID-19, NMRR-20-1379-55600 |
Phase Not Applicable |
Status not specified |
1 |
2 Months |
|
Dr Khalifah Nabilah Binti Mashar |
2020-07-14 |
| Remdesivir for the Treatment of COVID-19: A Scoping Review |
Coronavirus disease 19 infection |
remdesivir alone |
COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator |
|
Institute For Medical Research (Inc In Malaysia) |
|
Malaysia |
2020-07-24 |
2020-08-24 |
55660, NMRR-20-1369-55660 |
Phase Not Applicable |
Status not specified |
1 |
1 Month |
|
Nor Soleha binti Mohd Dali, dr Nor Asiah Muhamad |
2020-07-14 |
| COVID-19SWD: COVID-19 Surveillance Based on Smart Wearable Device |
Coronavirus disease 19 infection |
smart wearable device alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Peking University First Hospital |
|
China |
2020-07-01 |
2021-03-10 |
2020055-0615, COVID-19SWD, NCT04459637 |
Phase Not Applicable |
Not yet recruiting |
1 |
8 Months |
200 |
Cheng Zhang, Chunbo Zhang, Fangfang Guo, Guangfa Wang, Guangfa Wang, MD., Hong Zhang, Jing Ma, Jiping Liao, PhD., Yunxia Wang, Zhu Tian |
2020-07-10 |
| A phase II clinical trial of DWP-710 for the Covid-19 treatment |
Coronavirus disease 19 infection |
DWP-710 alone |
|
|
Daewoong Pharmaceutical Co Ltd |
|
South Korea |
|
|
|
Phase 2 Clinical |
Planned |
1 |
|
|
|
2020-07-12 |
| Coagulation Changes Associated With COVID-19 Infection |
Coronavirus disease 19 infection |
Quantra QPlus system alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hemosonics Llc |
|
US |
2020-07-27 |
2020-11-12 |
HEMCS-035, NCT04460664 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
50 |
Deborah A Winegar, PhD |
2020-07-13 |
| A phase I clinical trial of DWP-710 for the Covid-19 treatment |
Coronavirus disease 19 infection |
DWP-710 alone |
|
|
Daewoong Pharmaceutical Co Ltd |
|
Indonesia |
|
|
|
Phase 1 Clinical |
Not yet recruiting |
1 |
|
|
|
2020-07-12 |
| Treatment of Coronavirus COVID-19 Pneumonia (Pathogen SARS-CoV-2) With Cryopreserved Allogeneic P-MMSCs and UC-MMSCs |
Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia |
mechanical ventilation alone, supportive therapy alone, Оxygen therapy alone, Variable regimens including Cryopreserved placenta-derived multipotent mesenchymal stromal cell , azithromycin , ceftriaxone , dexamethasone , enoxaparin sodium |
Low molecular weight heparin |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Institute of Cell Therapy, Ukraine |
Kyiv City Clinical Hospital # 4 |
Ukraine |
2020-05-02 |
2021-12-31 |
#4/24.04.2020, NCT04461925 |
Phase 1/Phase 2 Clinical |
Recruiting |
1 |
19 Months |
30 |
Alexey Chibisov, MD, Alina Ustymenko, PhD, Peter Nemtinov, MD |
2020-07-10 |
| Open-label, Non-comparative Trial of the Combination of Hydroxychloroquine and Azithromycin in the Treatment of Hospitalized Patients |
Coronavirus disease 19 infection, Lower respiratory tract infection |
azithromycin plus hydroxychloroquine |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of New Mexico |
|
US |
2020-03-24 |
2025-03-24 |
20-156, NCT04458948 |
Phase 2 Clinical |
No longer recruiting |
1 |
60 Months |
10000 |
Cristina Beato |
2020-07-10 |
| A Phase II clinical trial of EIDD-2801 for the treatment of COVID-19 |
Coronavirus disease 19 infection |
EIDD-2801 alone |
RNA polymerase inhibitor |
|
Liverpool School of Tropical Medicine, Ridgeback Biotherapeutics LP, The University of Liverpool, University Of Southampton |
|
UK |
|
|
|
Phase 2 Clinical |
Recruiting |
1 |
|
|
Professor Saye Khoo |
2020-07-10 |
| Rapid, Onsite COVID-19 Detection |
Coronavirus disease 19 infection |
biological sampling alone, rapid onsite COVID-19 testing alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Wisconsin-Madison |
AIDS Vaccine Research Lab, National Institutes of Health |
US |
2020-07-31 |
2021-07-31 |
2020-0855, 5P51OD011106-59, A536300, NCT04460690, PROTOCOL VERSION 6/29/2020, SMPH/PATHOL-LAB MED/ANAT PATH |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
5000 |
David O'Connor, PhD, Kristi L Hall |
2020-07-15 |
| Administration of Allogenic UC-MSCs as Adjuvant Therapy for Critically-Ill COVID-19 Patients |
Coronavirus disease 19 infection, Leukopenia, Lymphocytopenia, Viral pneumonia |
Variable regimens including allogenic umbilical cord mesenchymal stem cells , azithromycin , oseltamivir |
Exo-alpha sialidase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Indonesia |
|
Indonesia |
2020-07-31 |
2020-09-30 |
ISMMSCCOVID19, NCT04457609 |
Phase 1 Clinical |
Recruiting |
5 |
2 Months |
40 |
Adhrie Sugiarto, MD, Ceva W Pitoyo, MD, Cleopas M Rumende, MD, PhD, Dita Aditianingsih, MD, PhD, Erlina Burhan, MD, PhD, Faisal Matondang, MD, Isabella K Liem, MD, PhD, Ismail H Dilogo, MD, PhD, Navy GHM Lolong Wulung, MD, Pompini A Sitompul, MD, RR D Handayani, MD, Radiana D Antarianto, MD, PhD, Rosa Marlina, MD, Telly Kamelia, MD, Titi Sundari, MD, Tri Kurniawati, BSc, Triya Damayanti, MD, PhD, Wahju Aniwidyaningsih, MD |
2020-07-10 |
| Association of Comorbidities With COVID-19 |
Autoimmune disease, Cancer, Cardiovascular disease, Collagen disease, Coronavirus disease 19 infection, Diabetes mellitus, End stage renal disease, Hypertension, Liver disease, Lung disease, Obesity, Vascular disease |
realtime PCR alone |
|
|
Assiut University |
|
Egypt |
2020-07-20 |
2020-11-20 |
COVID19, NCT04459390 |
Phase Not Applicable |
Not yet recruiting |
1 |
4 Months |
100 |
Hebatallah Hassan |
2020-07-13 |
| One Year Follow-ups of Patients Admitted to Spanish Intensive Care Units Due to COVID-19 |
Coronavirus disease 19 infection |
|
|
|
Centro De Investigación Biomédica En Red De Enfermedades Hepáticas Y Digestivas (Ciberehd) |
Barcelona Supercomputing Center - Centro Nacional De Supercomputación, Instituto de Salud Carlos III |
Spain |
2020-05-08 |
2021-05-31 |
CIBERESUCICOVID, NCT04457505 |
Phase Not Applicable |
Recruiting |
30 |
12 Months |
5000 |
Adrian A Ceccato, PhD., Adrián Ceccato, MD, Alejandro Rodriguez, MD, Amalia MARTINEZ DE LA GÁNDARA, MD, Ana Loza, MD, Ana Ortega Montes, MD, Angel Sanchez, Antoni Torres, Antoni Torres, PhD, Arturo Huerta Garcia, MD, Demetrio Carriedo, MD, Dolores Vila Fernández, MD, Elena BUSTAMANTE MUNGUIRA, MD, Elena Gallego, MD, Ferran Roche, MD, Guillermo Muñiz, MD, Ignacio Martinez, Jesús Caballero, MD, Jordi Riera, MD, José M Añon Elizalde, MD, Juan López Messa, MD, Lorenzo Socías Crespí, MD, Mari C de la Torre, MD, Maria L Martinez, MD, Nieves Carbonell, MD, Pablo Vidal Cortes, MD, Pedro Lara, MD, Rafael Máñez Mendiluce, Ricard Ferrer, MD, Ruth Jorge Garcia, Sergio Ossa, MD, Susana Sancho, MD, Victor Sagredo, MD |
2020-07-10 |
| SUROCO: Surgical Outcomes in Covid Patients - the SUROCO, Multicenter, Cohort Study (COVID-19) |
Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia |
surgical procedure alone |
|
|
Centre hospitalier de l'Université de Montréal (CHUM) |
CHU de Quebec-Universite Laval, Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Centre for Research of CHUS (CRCHUS), Hopital Du Sacre-Coeur De Montreal, Hopital Maisonneuve-Rosemont, Montreal Heart Institute, Research Institute of the McGill University Health Centre |
Canada |
2020-03-13 |
2021-04-13 |
19.386, NCT04458337, SUROCO |
Phase Not Applicable |
Recruiting |
1 |
13 Months |
120 |
François-Martin Carrier, MD, FRCPC, Julie Desroches, PhD, Monique Ruel, RN, CCRP |
2020-07-11 |
| Part Two of Novel Adoptive Cellular Therapy With SARS-CoV-2 Specific T Cells in Patients With Severe COVID-19 |
Coronavirus disease 19 infection, Dyspnea, Lung disease, Multiple organ failure, Respiratory failure, Septic shock |
SARS-CoV-2 specific T cells alone |
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
KK Women's and Children's Hospital |
Changi General Hospital Singapore, Duke-NUS Graduate Medical School, National University Hospital (Singapore) Pte Ltd, Sengkang General Hospital, Singapore General Hospital Pte Ltd |
Singapore |
2020-07-01 |
2022-12-31 |
COVID-T 2.0, NCT04457726 |
Phase 1/Phase 2 Clinical |
Recruiting |
5 |
30 Months |
18 |
Dr Linn Yeh Ching, Dr Tan Lip Kun, Jiashen Loh, Lip Kun Tan, Loh Jiashen, Michaela Seng, Roshni Sadashiv Gokhale, Wing Hang Leung, Yeh Ching Linn |
2020-07-16 |
| Sofosbuvir With and Without Ribavirin in Treatment of COVID 19 |
Coronavirus disease 19 infection |
Standard of card treatment alone, sofosbuvir alone, ribavirin plus sofosbuvir |
Hepatitis C virus NS5B polymerase inhibitor |
|
Tanta University |
|
Egypt |
2020-08-01 |
2021-08-31 |
NCT04460443, SOFOSBUVIR |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
13 Months |
60 |
Marwa Salama, Consultant, Sherief Abd-Elsalam, Ass. Prof. Tropical Medicine, Sherief Abd-Elsalam, ass. prof., sherief abd-elsalan, ass. prof. |
2020-07-10 |
| Effect of eating habits and exposure to light on sleep, emotion, memory and headache in college students during the COVID-19 pandemic |
Acute stress disorder, Cognitive disorder, Coronavirus disease 19 infection, Depression, Headache |
Adjusting sleep habits alone |
|
Young Adults (18-44 yrs) |
Universidade Federal de Pernambuco |
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior |
Brazil |
2020-06-29 |
|
32360720.4.0000.5208, 4.101.968, RBR-5kkpg6, U1111-1253-9533 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
2100 |
Mirian Celly Medeiros Miranda David, Rhowena Jane Barbosa de Matos |
2020-07-10 |
| SARS-RESPONSE control study: Cellular and Serological Immune Response Monitoring in SARS-CoV2-infected individuals, without need of hospitalization |
Coronavirus disease 19 infection |
SARS-CoV2 PCR testing alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Leiden University Medical Center |
|
Netherlands |
2020-06-22 |
2021-12-31 |
NL8745, P20.068, SARS-RESPONSE control study |
Phase Not Applicable |
Not yet recruiting |
1 |
18 Months |
10 |
Jacques J.M. van Dongen |
2020-07-14 |
| COVID-AGP: Risk of infection with SARS-CoV-2 amongst physicians |
Coronavirus disease 19 infection |
aerosol generating procedures alone |
|
|
Amsterdam UMC, Universitair Medisch Centrum Utrecht |
|
Netherlands |
2020-06-16 |
2021-07-16 |
COVID-AGP, METC-protocolnummer- 20-407/C, NL8735 |
Phase Not Applicable |
Not yet recruiting |
1 |
13 Months |
3000 |
Jennifer Breel |
2020-07-10 |
| Reducing the risk of COVID-19 spread in hospitals, by stopping droplets from spreading |
Coronavirus disease 19 infection |
dental rubber dam alone, fluorescein alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Queen Alexandra Hospital, University of Portsmouth |
|
UK |
2020-06-15 |
2022-03-01 |
IRAS 285515, ISRCTN10378358 |
Phase Not Applicable |
Not yet recruiting |
2 |
20 Months |
400 |
Prof. Richard Newsom |
2020-07-14 |
| DEFINE: Rapid Experimental Medicine for COVID-19 |
Coronavirus disease 19 infection, Lung injury, Respiratory disease, Respiratory failure |
standard of care alone, GB-0139 plus nafamostat mesilate |
Galectin-3 inhibitor |
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
NHS Lothian, University of Edinburgh |
LifeArc, University of Oxford |
UK |
2020-07-03 |
2021-12-03 |
2020-002230-32, AC20063, DEFINE, NCT04473053 |
Phase 2a Clinical |
Recruiting |
2 |
17 Months |
60 |
Annya Bruce, Annya Bruce, PhD, Kev Dhaliwal, Kevin Dhaliwal |
2020-07-17 |
| Effect of Allicin derivatives capsule in treatment of patients with new Coronavirus |
Coronavirus disease 19 infection |
Standard treatment alone, allicin derivative capsule alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Ferdowsi university of Mashhad |
|
Iran |
2020-06-21 |
|
IR.MUMS.REC.1399.289, IRCT20200610047722N1 |
Phase 0 Clinical |
Recruiting |
1 |
|
100 |
Amir Masoud Hashemian, Hossein Nik Tale, Saeedeh Ebrahimpour |
2020-07-17 |
| Effects of SVF and exosome in COVID-19 patients with acute respiratory distress syndrome |
Coronavirus disease 19 infection, Respiratory distress syndrome |
SVF separator (Lipogems) alone, Variable regimens including SVF autologous , SVF autologous fluid , blood exosome |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Tabriz University of Medical Sciences |
|
Iran |
2020-06-30 |
|
1399.095.IR.TBZMED.VCR.REC, IRCT20200510047385N1 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
|
60 |
Dr ata mahmoodpor, leila Roshangar, mehdi yosefi, mohammad samiei |
2020-07-10 |
| Convalescent Plasma in Pediatric COVID-19 |
Coronavirus disease 19 infection |
Standard COVID-19 therapy alone, convalescent plasma (CP) alone |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Emory University |
|
US |
2020-07-31 |
2022-06-30 |
NCT04458363, STUDY00000789 |
Phase 0 Clinical |
Recruiting |
1 |
23 Months |
50 |
Preeti Jaggi, MD |
2020-07-10 |
| Treatment of lung lesions with autologous stem cells in patients recovered from COVID-19 (COVID-19) |
Coronavirus disease 19 infection |
autologous stem cells alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Instituto de Hematología e Inmunología, Ministerio de Salud Publica |
|
Cuba |
2020-05-05 |
2020-12-15 |
RPCEC00000322 |
Phase 2 Clinical |
Recruiting |
1 |
7 Months |
20 |
Consuelo Macias Abraham |
2020-07-10 |
| Acute Kidney Injury and Renal Outcomes for COVID-19 Patients in Intensive Care Units |
Coronavirus disease 19 infection, Renal injury |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospices Civils De Lyon |
|
France |
2020-04-01 |
2020-11-30 |
COV-AKI_2020, NCT04459975 |
Phase Not Applicable |
Recruiting |
1 |
8 Months |
200 |
Denis FOUQUE, Professor, Maxime EPSI, Maxime ESPI |
2020-07-10 |
| Transfusion with convaling plasma immunizes the asymptomatic patient with Covid infection 19 that for > 30 days is positive SARS CoV-2 PCR (COVID-19) |
Coronavirus disease 19 infection |
plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Instituto de Hematología e Inmunología |
Ministerio de Salud Publica |
Cuba |
2020-05-05 |
2020-10-12 |
RPCEC00000323 |
Phase 2 Clinical |
Recruiting |
1 |
5 Months |
22 |
Consuelo Macias Abraham |
2020-07-13 |
| RIAL-COLECTOMY: Intracorporeal Anastomosis in Laparoscopic Left Colectomy. Cohort Comparative Study |
Adenocarcinoma, Colon tumor, Coronavirus disease 19 infection |
Curved B Braun Stapler alone, intracorporeal left hemicolectomy anastomosis alone, pursetring self-suturing device alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Corporacion Parc Tauli |
|
Spain |
2020-06-29 |
2022-02-28 |
HEMI-E-INTRACORPOREA-2020, NCT04456933, RIAL-COLECTOMY |
Phase Not Applicable |
Recruiting |
1 |
20 Months |
148 |
Xavier Serra-Aracil, MD,PhD |
2020-07-20 |
| PLAVID-TRIAL: Effect of COVID-19 convalescent plasma produced by HEMOPE: A randomized study, with a comparative group in several centers |
Coronavirus disease 19 infection |
convalescent plasma therapy alone, local standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universidade de Pernambuco |
Science and Technology of the State of Pernambuco |
Brazil |
2020-07-01 |
|
31400920.2.0000.5192, 4.100.150, PLAVID-TRIAL, RBR-7jqpnw, U1111-1254-0612 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
220 |
Democritus of Barros Miranda Filho |
2020-07-11 |
| NACOVID: The Nitazoxanide Plus Atazanavir for COVID-19 Study |
Coronavirus disease 19 infection |
Standard of Care alone, atazanavir + ritonavir plus nitazoxanide |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Obafemi Awolowo University |
African Centre of Excellence for Genomics of Infectious Diseases, Oyo State Ministry of Health, The University of Liverpool |
Nigeria |
2020-08-01 |
2020-12-31 |
NACOVID, NACOVID2020, NCT04459286 |
Phase 2 Clinical |
Not yet recruiting |
1 |
5 Months |
98 |
Adeniyi Olagunju, PhD, Adeola Fowotade, MBBS, Olabode Ladipo, MBBS |
2020-07-13 |
| Project H-COVID: Evaluating Hyper-Brief, Online Materials During the COVID-19 Pandemic |
Anxiety disorder, Coronavirus disease 19 infection |
Contain COVID Anxiety SSI alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Stony Brook University Hospital |
|
|
2020-07-31 |
2020-08-31 |
IRB2020-00204, NCT04459455, Project H-COVID |
Phase Not Applicable |
Not yet recruiting |
0 |
1 Month |
500 |
Michael Mullarkey, M.A. |
2020-07-09 |
| Using Caring Contacts to Reduce Psychiatric Morbidity Following Hospitalization During the COVID-19 Pandemic |
Anxiety disorder, Coronavirus disease 19 infection, Depression, Psychiatric disorder |
Caring Contacts alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sunnybrook Health Sciences Centre |
|
Canada |
2020-07-31 |
2021-03-31 |
1804, NCT04456062 |
Phase Not Applicable |
Not yet recruiting |
1 |
8 Months |
150 |
Ayal Schaffer, MD, Rosalie Steinberg, MD |
2020-07-20 |
| W-SUDs for COVID-19 |
Coronavirus disease 19 infection |
Woebot Substance Use Disorder alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Woebot Labs Inc |
Stanford University |
US |
2020-06-22 |
2020-08-31 |
56439, NCT04460027 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
160 |
Judith Prochaska |
2020-07-09 |
| Effect of Availability of COVID-19 Testing on Choice to Isolate and Socially Distance |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of California Los Angeles |
|
US |
2020-07-31 |
2020-07-31 |
IRB-20-000980, NCT04459520 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
690 |
Daniel M Croymans, MD, Daniel M. Croymans |
2020-07-09 |
| SCOUT-2: SARS-CoV-2 immune response in asymptomatic patients |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Amsterdam UMC |
|
Netherlands |
2020-06-01 |
2021-06-01 |
METC 2020_138, NL8733, SCOUT-2 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
75 |
Annemieke van den Broek |
2020-07-11 |
| COVID-19 Vaccine Messaging Randomized, Controlled Trial, Part 1 |
Coronavirus disease 19 infection |
Anger message alone, Baseline message alone, Community interest message alone, Control message alone, Economic benefit message alone, Economic freedom message alone, Embarrassment message alone, Guilt message alone, Not bravery message alone, Personal freedom message alone, Self-interest message alone, Trust in science message alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Yale University |
|
|
2020-07-03 |
2020-07-31 |
COVIDVACCINEPERSUASION1, NCT04460703 |
Phase Not Applicable |
Not yet recruiting |
0 |
|
4000 |
|
2020-07-09 |
| Tele-Yoga Therapy for Chronic Pain |
Coronavirus disease 19 infection, Pain |
Breathing exercises alone, Postures alone, Relaxation techniques and chanting alone, Tele-Yoga Therapy alone, meditation alone, yoga loosening exercises alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Aarogyam UK |
|
UK |
2020-03-25 |
2020-06-15 |
AU/018, NCT04457388 |
Phase Not Applicable |
Completed |
1 |
2 Months |
18 |
Bhavna Pandya, Dipa Modi, Neha Sharma |
2020-07-20 |
| Feasibility of a Brief Trauma-informed Yoga Intervention for Anxiety During the Coronavirus Disease (COVID-19) Pandemic |
Anxiety disorder, Coronavirus disease 19 infection |
Trauma-informed yoga video recording alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National College of Natural Medicine |
|
US |
2020-07-31 |
2020-10-31 |
NCT04453514, TIBBITTS_TIYOGA_COVID |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
200 |
Deanne Tibbitts, PhD |
2020-07-20 |
| AnhandCOV19: Feasibility and Benefits of Digital Services During the COVID19 Pandemic |
Coronavirus disease 19 infection, Psychiatric disorder |
Online depression session- flipped classroom alone, socio-medical content alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Jacobs University Bremen GmbH |
Paracelsus-Klinik Bremen |
Germany |
2020-07-01 |
2021-12-31 |
ANHAND-COVID19, AnhandCOV19, NCT04453475 |
Phase Not Applicable |
Not yet recruiting |
1 |
18 Months |
1230 |
Alina Dahmen, Dr. med., Katja Odin, Dr. med., Sonia Lippke, Prof. Dr. |
2020-07-20 |
| Cov-EMERALD: Early EMDR Following Covid-19 Critical Illness: A Feasibility Trial |
Anxiety disorder, Cognitive disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder |
Eye Movement Desensitisation and Reprocessing Recent traumatic Event Protocol alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Southampton NHS Foundation Trust |
Dorset HealthCare University NHS Foundation Trust |
UK |
2020-08-01 |
2021-05-31 |
Cov-EMERALD, NCT04455360, PROTOCOL VERSION 1.2 |
Phase Not Applicable |
Not yet recruiting |
1 |
10 Months |
26 |
Andrew C Bates, BA, Michael P Grocott, MD, Rebecca Cusack, MD |
2020-07-20 |
| Home-based Aerobic Training Among Adolescents With Chronic Diseases During COVID-19 Pandemic |
Arthritis, Autoimmune hepatitis, Coronavirus disease 19 infection, Dermatomyositis, Immune disorder, Inflammatory bowel disease, Kidney transplantation, Liver transplantation, Renal disease, Systemic lupus erythematosus |
online home-based aerobic training alone |
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
University of Sao Paulo |
|
Brazil |
2020-07-31 |
2021-06-30 |
31314220.5.0000.0068, NCT04458246 |
Phase Not Applicable |
Recruiting |
1 |
11 Months |
140 |
Bruno Gualano, PhD, Bruno Gualano, Phd |
2020-07-20 |
| Simple Cognitive Task Intervention After Trauma During COVID-19 In Hospital Staff EKUT-P RCT |
Coronavirus disease 19 infection, Injury, Post traumatic stress disorder |
Simple cognitive task intervention alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Karolinska Institutet |
|
Sweden |
2020-07-01 |
2021-06-01 |
2020-03085, NCT04460014 |
Phase Not Applicable |
Not yet recruiting |
1 |
11 Months |
164 |
Emily Holmes, Prof, Marie Kanstrup, PhD |
2020-07-20 |
| Efficacy of Intranasal Probiotic Treatment to Reduce Severity of Symptoms in COVID19 Infection |
Coronavirus disease 19 infection |
Probiorinse alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Centre hospitalier de l'Université de Montréal (CHUM) |
|
Canada |
2020-07-07 |
2020-12-31 |
249512, NCT04458519, PROBCO |
Phase Not Applicable |
Not yet recruiting |
1 |
5 Months |
40 |
Leandra Mfuna Endam, MSc, Martin Y Desrosiers, MD |
2020-07-09 |
| Therapeutic Plasma Exchange in Resistant Cytokine Storm of COVID 19 |
Coronavirus disease 19 infection |
Therapeutic Plasma Exchange (TPE) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Alexandria |
|
Egypt |
2020-07-20 |
2020-12-29 |
NCT04457349, PLASMA EXCHANGE IN COVID 19 |
Phase Not Applicable |
Not yet recruiting |
1 |
5 Months |
10 |
Akram M Fayed, MD, Ayman I Baess, MD, Ehab M El Reweny, MD, Mohamed Mamdouh Elsayed, MD, Nermine H Zakaria, MD, montasser M zeid, MD |
2020-07-11 |
| PRANA: A Study to Evaluate OP-101 (Dendrimer N-acetyl-cysteine) in Severe Coronavirus Disease 2019 (COVID-19) Patients |
Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory tract infection |
OP-101 alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Orpheris Inc |
|
US |
2020-07-01 |
2020-11-10 |
NCT04458298, OP-101-004, PRANA |
Phase 2 Clinical |
Recruiting |
1 |
4 Months |
24 |
H. Bryant Nguyen, MD, Jeffrey L. Cleland, Executive Chair, Co-founder |
2020-07-09 |
| NeuroSARS: Neurological Features During COVID19 |
Ageusia, Bradycardia, Confusion, Coronavirus disease 19 infection, Epilepsy, Hypertension, Hypotension, Hypothermia, Inappropriate ADH syndrome, Movement disorder, Sensory disorder, Tachycardia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre d'Investigation Clinique et Technologique 805 |
|
France |
2020-03-08 |
2020-09-30 |
BRAIN COVID, NCT04460599, NeuroSARS |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
30 |
DAVID ORLIKOWSKI, MD PHD, David Orlikowski, MD PhD, Eric Azabou, MD, Isabelle Bossard, Marie Christine Durand, MD, Robert Carlier, MD PHD, david orlikowski, Professor |
2020-07-11 |
| COPID19: COVID-19 in PID Survey |
Coronavirus disease 19 infection, Immune deficiency |
|
|
|
Imagine Institute |
|
France |
2020-03-15 |
2022-03-31 |
COPID19, COPID19, NCT04459689 |
Phase Not Applicable |
Recruiting |
1 |
24 Months |
200 |
Hassan FAOUR, BS, Nizar MAHLAOUI, MD, MPH, PhD |
2020-07-09 |
| COFICS: COVID-19 Follow-up Intensive Care Studies |
Coronavirus disease 19 infection, Respiratory distress syndrome |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Medical Center Groningen |
Hanze University of Applied Sciences |
Netherlands |
2020-07-01 |
2022-02-01 |
COFICS, COFICS201800422, NCT04460170 |
Phase Not Applicable |
Not yet recruiting |
1 |
19 Months |
100 |
I van der Meulen, PhD, Willem Dieperink |
2020-07-09 |
| Psychiatric Disturbances and COVID-19 Infection |
Anxiety disorder, Coronavirus disease 19 infection, Depression, Psychiatric disorder |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cairo University |
Ministry of Health and Population, National Hepatology & Tropical Medicine Research Institute |
Egypt |
2020-06-08 |
2020-09-15 |
15-2020/1, NCT04459403 |
Phase Not Applicable |
Recruiting |
3 |
3 Months |
200 |
Hend I Shousha, M.D, Rabab Maher, M.D, Shaima Afifi, M.D, Shaimaa Afifi, M.D, amr Abdelazeem, MSc, basem elsayed, M.D, mohamed elkassass, M.D |
2020-07-10 |
| PHENOTYPE: Phenotyping patients Admitted to Hospital With covid-19 Infection and identifying Prognostic markers |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Chelsea & Westminster NHS Trust |
|
UK |
2020-06-19 |
2023-06-30 |
C&W20/035, NCT04459351, PHENOTYPE |
Phase Not Applicable |
Recruiting |
1 |
36 Months |
500 |
Pallav Shah, Pallav Shah, MBBS, MD, Research Delivery Operations Manager |
2020-07-10 |
| Pulmonary rehabilitation in individuals affected by Covid-19 |
Coronavirus disease 19 infection |
Aerobic exercises alone, Health education alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Midwestern University |
|
Brazil |
2020-06-06 |
|
31798320.4.0000.0106, 4,059,561, RBR-4wnx2q, U1111-1254-1089 |
Phase Not Applicable |
Recruiting |
1 |
|
152 |
Christiane Riedi Daniel |
2020-07-14 |
| Anxiety Level and Oral Hygiene Practice in Dental Students During COVID-19 Pandemic |
Anxiety disorder, Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted |
Cairo University |
|
Egypt |
2020-07-01 |
2020-09-30 |
MAI ZAKARIA 4, NCT04460469 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
1500 |
Basma Elsaadany, Ph, Mai Zakaria, Ph |
2020-07-09 |
| A Study of Combination Therapies to Treat COVID-19 Infection |
Coronavirus disease 19 infection |
Variable regimens including azithromycin , hydroxychloroquine , lopinavir , ritonavir |
Cytochrome P450 3A4 inhibitor, HIV protease inhibitor, HIV-1 protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
ProgenaBiome |
Big Corona Ltd |
US |
2020-07-31 |
2021-12-31 |
NCT04459702, PRG-043 |
Phase 2a Clinical |
Not yet recruiting |
1 |
17 Months |
200 |
Jordan Daniels, MS, Sabine Hazan, MD, Thomas Borody, MD, PhD, |
2020-07-09 |
| COVISPERM: Detection of COVID-19 (SARS-CoV-2) in the Semen of COVID+ Patients (Positive RT-PCR on a Nasopharyngeal Swab) |
Coronavirus disease 19 infection |
RT-PCR alone |
|
Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
GCS Ramsay Santé pour l’Enseignement et la Recherche |
|
France |
2020-05-07 |
2021-08-31 |
2020-A01206-33, COVISPERM, NCT04460534 |
Phase Not Applicable |
Recruiting |
1 |
15 Months |
100 |
Lucie DELAROCHE, Pharm D, Pierre OGER, MD |
2020-07-09 |
| Healthcare Renunciation During the Confinement Period in Connection With the COVID-19 Epidemic in Adult Emergency Departments |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital, Angers |
|
France |
2020-07-08 |
2020-12-31 |
49RC20_0155, NCT04460196 |
Phase Not Applicable |
Recruiting |
3 |
5 Months |
900 |
DRCI Promotion Interne, DUPONT Clémence, Delphine DOUILLET |
2020-07-16 |
| A trial to assess safety and efficacy of erythropoietin in the treatment of Covid-19 |
Coronavirus disease 19 infection |
erythropoietin alone |
|
|
Max-Planck Gesellschaft zur Förderung Der Wissenschaften eV |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-07-08 |
| Using Tocilizumab in critically ill patients with COVID-19 |
Coronavirus disease 19 infection |
Tocilizumab alone, organic support therapy alone, standard intensive care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Universitario Antonio Pedro |
|
Brazil |
2020-03-16 |
|
4.059.207, CAAE 29496920.8.0000.5262, RBR-3zdynp, U1111-1252-7966 |
Phase 2 Clinical |
Recruiting |
1 |
|
60 |
Victor Côrtes Pourchet de Carvalho |
2020-07-14 |
| COVID-19 Breath Test |
Coronavirus disease 19 infection |
NBT system alone, breath test alone, nanotechnology biomarker tagging (NBT) alone |
|
Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ancon Technologies Ltd |
|
UK |
2020-06-29 |
2021-06-14 |
2020ATL01, NCT04459962 |
Phase Not Applicable |
Recruiting |
1 |
11 Months |
250 |
Freda M Gomes, Isaac John, PhD, Linda Pomeroy, PhD, Stephen Winchester, MBBS, MSc |
2020-07-09 |
| Study to Assess Efficacy and Safety Relative to Standard of Care in Patients With COVID-19 Pneumonia |
Coronavirus disease 19 infection, Lung disease, Renal disease, Viral pneumonia |
ANG-3777 alone, standard of care alone |
Hepatocyte growth factor receptor agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Angion Biomedica Corp |
CTI Clinical Trial and Consulting Services |
Brazil |
2020-07-31 |
2020-10-31 |
ANG3777-ALI-201, NCT04459676 |
Phase 2 Clinical |
Not yet recruiting |
7 |
3 Months |
100 |
Deb Gouveia, John Neylan, MD |
2020-07-18 |
| PREPARE-IT: Prevention of COVID-19 With EPA in Healthcare Providers at Risk - Intervention Trial |
Coronavirus disease 19 infection |
icosapent ethyl, Amarin alone |
Apolipoprotein B antagonist, Phospholipase A2 inhibitor |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Estudios Clinicos Latino America |
Amarin Pharmaceuticals Inc |
Argentina |
2020-07-31 |
2020-12-31 |
NCT04460651, PREPARE-IT, PREPARE-IT. VERSION 1.2 |
Phase 3 Clinical |
Not yet recruiting |
1 |
5 Months |
1500 |
Andres Orlandini, MD, Rafael Diaz, MD |
2020-07-10 |
| SHADE: Short-Term, High-Dose Vitamin D Supplementation for COVID-19 |
Coronavirus disease 19 infection, Vitamin D deficiency |
vitamin D alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Postgraduate Institute of Medical Education and Research |
|
India |
2020-06-15 |
2020-07-10 |
121/20, NCT04459247, SHADE |
Phase Not Applicable |
Recruiting |
1 |
|
30 |
Ashu Rastogi, MD, DM |
2020-07-10 |
| Compensatory Reserve Index (CRI) for Management of COVID-19 |
Coronavirus disease 19 infection |
CRI management alone, CipherOx CR T1 tablet alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
University of Colorado at Denver and Health Sciences Center |
Children's Hospital Colorado |
US |
2020-07-31 |
2021-09-30 |
20-1406, NCT04457817 |
Phase Not Applicable |
Not yet recruiting |
1 |
14 Months |
100 |
Jenny Stevens, MD, Marina Reppucci, MD, Steven L Moulton, MD |
2020-07-09 |
| Betadine Effect on Nasal Mucosa Cilia |
Coronavirus disease 19 infection, Respiratory tract infection |
povidone-iodine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Boston Medical Center Corp |
|
US |
2020-08-31 |
2021-12-31 |
H-40432, NCT04457765 |
Phase 0 Clinical |
Not yet recruiting |
1 |
16 Months |
10 |
Jennifer Shehan, MD, Waleed Ezzat, MD |
2020-07-11 |
| An investigator-initiated study to evaluate CK-0802 for the treatment of patients with COVID-19 induced acute respiratory distress syndrome |
Coronavirus disease 19 infection, Respiratory distress syndrome |
CK-0802 alone |
|
|
Cellenkos Inc |
|
US |
|
|
|
Phase 2 Clinical |
Status not specified |
1 |
|
2 |
Dr. Douglas Gladstone |
2020-07-08 |
| COVID Kids Bavaria: Clinical translational and epidemiological research project on SARS coronavirus 2 infection in during the COVID 19 pandemic children in Bavaria |
Coronavirus disease 19 infection |
nasopharynx swab (COVID-19 PCR) alone, questionnaire alone |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs) |
Dr. von Hauner Children’s Hospital |
Bayerisches Staatsministerium für Wissenschaft und Kunst |
Germany |
2020-07-12 |
|
20-538, COVID Kids Bavaria, DRKS00022380 |
Phase Not Applicable |
Recruiting |
1 |
|
14000 |
Anna Kern, Nicole Maison |
2020-07-13 |
| FTR-COVID: Respiratory Physiotherapy in Severe COVID-19 Patients |
Coronavirus disease 19 infection, Hypoxia, Respiratory failure, Viral pneumonia |
airway clearance alone, early mobilization alone, invasive mechanical ventilation weaning alone, muscle-strengthening exercises alone, non-invasive mechanical ventilation / CPAP alone, oxygen titration alone, respiratory physiotherapy alone, tracheostomy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fondazione IRCCS Ca' Granda-Ospedale Maggiore Policlinico |
|
Italy |
2020-03-01 |
2020-07-30 |
FTR-COVID, FTR-COVID, NCT04459819 |
Phase Not Applicable |
Recruiting |
1 |
4 Months |
80 |
Emilia Privitera, MSC, Martina Santambrogio, PhD |
2020-07-09 |
| The Prevalence of Pulmonary Hypertension in Patients With COVID-19 |
Coronavirus disease 19 infection, Pulmonary hypertension |
echocardiography alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
AttgeNO AB |
|
Sweden |
2020-06-01 |
2020-07-10 |
20200422PA, NCT04459364 |
Phase Not Applicable |
Recruiting |
1 |
1 Month |
80 |
Per-Arne Lönnqvist, Professor |
2020-07-09 |
| 3D Telemedicine During COVID-19: Cohort Study |
Breast tumor, Cleft lip, Coronavirus disease 19 infection, Head and neck tumor, Sarcoma, Skin burns |
3D Telemedicine alone |
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
NHS Greater Glasgow and Clyde |
Jean Brown Bequest Fund, Glasgow |
UK |
2020-09-01 |
2021-01-01 |
GN20HS300, NCT04444323 |
Phase Not Applicable |
Not yet recruiting |
1 |
4 Months |
50 |
|
2020-07-20 |
| To study the role of zinc combined with standard treatment for COVID-19 |
Coronavirus disease 19 infection |
standard treatment alone, zinc sulphate alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Wockhardt Hospitals |
|
India |
2020-07-11 |
|
CTRI/2020/07/026340 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Ramen Goel |
2020-07-09 |
| Understanding COVID and cancer |
Cancer, Coronavirus disease 19 infection |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tata Memorial Centre |
|
India |
2020-07-15 |
|
CTRI/2020/07/026339 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1000 |
C S Pramesh |
2020-07-09 |
| Effectiveness of Measles, Mumps and Rubella Vaccine in Health Care Professionals for COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
Measles Mumps and Rubella alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Dar Al Fouad Hospital |
|
Egypt |
2020-07-01 |
|
PACTR202006883882711 |
Phase 2 Clinical |
Not yet recruiting |
2 |
|
200 |
Amani El Kholy, Doaa Nagy, Hend Ibrahim, Jehan El Kholy, Mostafa Alfishawy |
2020-07-09 |
| Stress and coping among healthcare workers during COVID-19 outbreak |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Sri Ramachandra Institute of Higher Education and Research |
|
India |
2020-07-15 |
|
CTRI/2020/07/026350 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
150 |
Dr Suvarna Jyothi Kantipudi |
2020-07-08 |
| Knowledge, Attitudes and Practices (KAP) Study on COVID-19 in Maryland, Liberia |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Heidelberg |
Deutsche Forschungsgemeinschaft (DFG), Deutsche Gesellschaft fur Internationale Zusammenarbeit [GIZ] GmbH, German Federal Ministry of Education and Research |
Liberia |
2020-05-28 |
2020-06-28 |
DRKS00022371, NREB-APV-014-20, U1111-1254-6575 |
Phase Not Applicable |
Completed |
1 |
1 Month |
500 |
Iona Thomas-Connor, Peter Dambach |
2020-07-07 |
| Effect of awake proning in patients with COVID-19 related respiratory failure |
Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure |
prone positioning alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
All India Institute of Medical Sciences |
|
India |
2020-07-04 |
|
CTRI/2020/07/026349 |
Phase 3 Clinical |
Recruiting |
1 |
|
20 |
Anant Mohan |
2020-07-08 |
| Nebulized heparin in patients with mainly moderate coronavirus disease 2019: Randomized controlled trial. COVID-19 |
Coronavirus disease 19 infection |
heparin alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Faculty of Medicine, University of Alexandria |
|
Egypt |
2020-06-15 |
2020-07-31 |
PACTR202007606032743 |
Phase 2 Clinical |
Recruiting |
1 |
1 Month |
100 |
Amal Mohamed, Dr Rabab S. Mahrous, Tarek Salem, Tarek ismail |
2020-07-08 |
| SLKovid: Seroprevalence of SARS-CoV-2 in employees of a clinic with COVID-center (COVID-19) |
Coronavirus disease 19 infection |
serological antibody test alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
SLK Klinikum Heilbronn GmbH |
Zweckgebundene Privatspende |
Germany |
2020-07-01 |
|
DRKS00022226, F-2020-085, SLKovid |
Phase Not Applicable |
Recruiting |
1 |
|
5000 |
Dilyana Vladimirova, Uwe Martens |
2020-07-08 |
| LACBSOT: Lagos COVID-19 Black Seed Oil Trial |
Coronavirus disease 19 infection |
Black seed oil alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Lagos State Ministry of Health |
|
Nigeria |
2020-09-01 |
2020-10-23 |
LACBSOT, PACTR202007611764617 |
Phase Not Applicable |
Not yet recruiting |
1 |
1 Month |
80 |
AbdulWasiu Busari, Hussein AbdurRazzaq, Ibrahim Oreagba |
2020-07-08 |
| Ayurvedic Rasayana treatment as an add-on therapy to improve the results in management of coronavirus disease |
Coronavirus disease 19 infection |
standard of care therapy alone, Pranvir plus Yashada Rasayana |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Yashwantrao Chavan Memorial Hospital |
|
India |
2020-07-11 |
|
AR/RC/T-01, CTRI/2020/07/026343 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
200 |
Dr Avinash Kadam, Dr Mahesh Asalkar |
2020-07-09 |
| RDC19: Clinical features of patients with rheumatic diseases and COVID-19 infection in Sarawak, Malaysia |
Coronavirus disease 19 infection, Musculoskeletal disease |
|
|
|
Sarawak General Hospital |
|
Malaysia |
2020-07-03 |
2020-07-31 |
55569, NMRR-20-1362-55569, RDC19 |
Phase Not Applicable |
No longer recruiting |
1 |
|
|
Dr Sharifah Aishah bt Wan Mohamad Akbar |
2020-07-09 |
| Evaluation of the effect of sofosbuvir/daclatasvir in COVID-19 patients |
Coronavirus disease 19 infection |
sofosbuvir + daclatasvir alone, standard pharmaceutical protocol alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Abadan University of Medical Sciences |
|
Iran |
2020-07-08 |
|
IR.ABADANUMS.REC.1399.071, IRCT20200624047908N1 |
Phase 3 Clinical |
Recruiting |
2 |
|
600 |
Gholamali Eslami |
2020-07-17 |
| Rapid response Covid-19 Bera district |
Coronavirus disease 19 infection |
|
|
|
PEJABAT KESIHATAN DAERAH BERA |
|
Malaysia |
2020-06-04 |
2020-08-04 |
55363, NMRR-20-1357-55363 |
Phase Not Applicable |
Status not specified |
1 |
2 Months |
|
DR MOHAMMAD LOKMAN HAKIM BIN MAT ISAR, Wan Intan Fairouza Binti Wan Shahibi |
2020-07-09 |
| Effect of vitamin D supplementation in COVID-19 |
Coronavirus disease 19 infection |
vitamin D (ZAHRAVI ) plus vitamin D syrup (Pharmacology Mashhad University of Medical Sciences) |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Mashhad University of Medical Sciences |
|
Iran |
2020-06-21 |
|
IR.MUMS.REC.1399.237, IRCT20110726007117N11 |
Phase 3 Clinical |
Recruiting |
1 |
|
210 |
Doctor Majid Ghayour Mobarhan, Doctor Mohsen Tafaghodi, Zahra Khorasanchi, ِDoctor Majid Ghayour Mobarhan |
2020-07-08 |
| A study to assess safety and efficacy of T Cell Therapy for COVID-19 patients |
Coronavirus disease 19 infection |
TCB-007 alone |
|
|
TC BioPharm Ltd |
|
UK |
|
|
|
Phase Not Applicable |
Planned |
1 |
|
|
Nik Hirani |
2020-07-13 |
| Clinical trial of ozone therapy in mild to moderate Covid-19 subjects |
Coronavirus disease 19 infection |
ozone therapy alone, standard care alone |
|
|
Lokmanya Tilak Municipal Medical College and General Hospital |
|
India |
2020-07-13 |
|
CTRI/2020/07/026354, MHC/CT/20-21/005 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
|
60 |
Dr Jignasha Captain, Dr Mili Shah |
2020-07-08 |
| The efficacy and safety of mesenchymal stem cell transplantation in patients with COVID-19 pneumonia |
Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory tract infection, Viral pneumonia |
routine treatment alone, umbilical core-derived mesenchymal stem cell transplantation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Hamadan University of Medical Sciences |
|
Iran |
2020-07-22 |
|
IR.UMSHA.REC.1399.330, IRCT20200426047206N2 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
30 |
Salman Khazaei, Sara Soleimani Asl, Sara Soleimani asl |
2020-07-08 |
| Effect of Thalidomide in Covid-19 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
hydroxichloroquine plus thalidomide (Ibn Sina Company) |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Isfahan University of medical Sciences |
|
Iran |
2020-05-09 |
|
IR.MUI.MED.REC.1399.048, IRCT20200428047232N1 |
Phase 3 Clinical |
No longer recruiting |
1 |
|
60 |
Samane Pourajam, Samane pourajam, Shaghayegh Haghjoo |
2020-07-08 |
| Giloy Gomutra Capsule, Asthi churna aur Kamdhenu Asava ka vaishvik mahamari Covid-19 par Ayurvedic Research |
Coronavirus disease 19 infection |
Variable regimens including Asthi Churna , Giloy gaumutra Capsule , Kamdhenu Asava |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Bansi Gir Gaushala |
|
|
2020-07-12 |
|
CTRI/2020/07/026353 |
Phase 2 Clinical |
Not yet recruiting |
0 |
|
30 |
Dr Dineshchandra Pandya, Dr Urvi Pandya |
2020-07-08 |
| Software for COVID19 Detection from Chest X-Ray, CT or Ultrasonography |
Coronavirus disease 19 infection |
CT or Ultrasonography alone, Chest X-Ray alone |
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kalinga Institute of Medical Sciences |
|
India |
2020-07-14 |
|
CTRI/2020/07/026351 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1000 |
Abhishek Biswas, Dr Nirmal Mohakud |
2020-07-08 |
| Study to assess the Health care workers’ knowledge of the Medical cause of death certification for COVID-19 related deaths in cancer patients |
Coronavirus disease 19 infection |
teaching intervention alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Tata Memorial Centre |
|
India |
2020-07-13 |
|
CTRI/2020/07/026338 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
90 |
Divya Khanna |
2020-07-09 |
| The Covid-19 Study with Ayurveda add-on to ICMR Guideline |
Coronavirus disease 19 infection |
Ayurveda formulations alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Government Stanley Medical College Hospital, Ministry of Ayush |
|
India |
2020-07-11 |
|
CTRI/2020/07/026337 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
36 |
Dr P Balaji, Dr Somit Kumar, Sujith Subash Eranezhath |
2020-07-08 |
| Kabasura Kudineer, Shakti drops and Turmeric plus in the management of COVID-19 |
Coronavirus disease 19 infection |
allopathic medicines alone, Variable regimens including Kabasura kudineer , Shakti Drops , Turmeric plus |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Sriveda Sattva PvtLtd |
|
India |
2020-07-13 |
|
CTRI/2020/07/026371 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
30 |
Dr M Ravi Kumar Reddy, Dr Ranganatha R |
2020-07-09 |
| A Mixed Method Comparative Study on Coping Mechanisms among Covid-19 Nursing Frontliners from Three Different Units (ICU,HDU and Wards) in Klang Valley Government Hospitals |
Coronavirus disease 19 infection |
|
|
|
Kolej Universiti Antarabangsa PICOMS |
|
Malaysia |
2020-08-01 |
2021-01-30 |
NMRR-20-1340-55214 |
Phase Not Applicable |
Not yet recruiting |
1 |
5 Months |
|
NORHANAZA BINTI MOHD YUNOS |
2020-07-08 |
| Evaluation of the performance of rapid diagnostic kit (COVIDAB-SP) in the detection of COVID-19 virus antibody |
Coronavirus disease 19 infection |
COVIDAB-SP alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Capital Health Services India Pvt Ltd |
|
India |
2020-07-14 |
|
CTRI/2020/07/026370 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
2000 |
Dr R Arunkumar |
2020-07-09 |
| Knowledge and Behaviors toward Antibiotics Use and Infection Prevention |
Coronavirus disease 19 infection |
|
|
|
Hospital Raja Permaisuri Bainun |
|
Malaysia |
2020-07-01 |
2020-12-31 |
NMRR-20-1336-55250 |
Phase Not Applicable |
Status not specified |
1 |
6 Months |
|
Chang Chee Tao, Ms Thong Kah Shuen |
2020-07-08 |
| Evaluation of the performance of rapid diagnostic kit (COVIDAG-SP) in the detection of COVID-19 virus antigen |
Coronavirus disease 19 infection |
COVIDAG-SP Kit alone, Naso Pharyngeal swab, Saliva and Serum sample alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Capital Health Services India Pvt Ltd |
|
India |
2020-07-14 |
|
CTRI/2020/07/026369 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
500 |
Dr R Arunkumar |
2020-07-08 |
| The association between the neutralizing activity and the amount of antibody in the convalescence stage of SARS-CoV-2 infection: A multicenter, observational study |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Yokohama City University |
Japan Agency for Medical Research and Development |
Japan |
2020-08-17 |
|
UMIN000041021 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
140 |
Atsushi Goto, Takeharu Yamanaka |
2020-07-09 |
| A prospective, open-label, single-arm multicenter pilot study to evaluate the effect off-label use of tocilizumab (TCZ) in hospitalized adult patients with severe COVID-19 |
Coronavirus disease 19 infection |
tocilizumab alone |
|
|
University of Turin |
|
|
|
|
|
Phase 2 Clinical |
Status not specified |
0 |
|
63 |
|
2020-07-07 |
| Spread of corona virus disease and factors affecting it in Pune city |
Coronavirus disease 19 infection |
questionnaire alone |
|
Healthy volunteers accepted, Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Byramjee Jeejeebhoy Govt Medical College and Sassoon General Hospitals |
Health Department Pune Municipal Corporation Pune |
India |
2020-07-13 |
|
CTRI/2020/07/026368 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
700 |
Dr Ganesh Jagdale, Dr Malangori Parande |
2020-07-08 |
| Evaluation Of The Efficacy of AYUSH KWATH in The Prevention of COVID-19 |
Coronavirus disease 19 infection |
ayush kwath alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Dr.S R.Rajasthan Ayurved University Jodhpur |
|
India |
2020-07-14 |
|
CTRI/2020/07/026355 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
500 |
Prof Dr Abhimanyu Kumar |
2020-07-08 |
| VERARE: Effectiveness of Virtual Motor Actions for Improving Walking in Patients With Post-resuscitation Muscle Weakness |
Coronavirus disease 19 infection, Muscle weakness |
haptic stimulation alone, headphone alone, sensory feedback alone, soothing music therapy alone, vibrator alone, virtual headset alone, virtual reality actions alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Rennes University Hospital |
INRIA Institut National de Recherche en Informatique et en Automatique |
France |
2020-08-01 |
2023-08-01 |
2020-A01722-37, 35RC20_8897_VERARE, NCT04441164, VERARE |
Phase Not Applicable |
Not yet recruiting |
1 |
36 Months |
510 |
Mélanie COGNE, MD |
2020-07-08 |
| Spanish PICNIC: A Randomized, Open-Label Clinical Study Evaluating the Impact of EnteraGam, a Nutritional Intervention Containing Bovine Plasma-Derived Immunoglobulin CoNcentrate, on Clinical Outcomes In People with COVID-19 |
Coronavirus disease 19 infection |
EnteraGam alone, standard of care alone |
|
|
Entera Health |
|
Spain |
|
|
Spanish PICNIC |
Phase Not Applicable |
Not yet recruiting |
1 |
|
420 |
Netanya Utay |
2020-07-07 |
| Multicenter, open, prospective, randomized, comparative study to study the safety and efficacy of the drug Fabivirin (INN: favipiravir), film-coated tablets 200 mg (Pharmasintez JSC, Russia) in the treatment of patients hospitalized with COVID-19 |
Coronavirus disease 19 infection |
favipiravir alone |
RNA polymerase inhibitor |
|
Pharmasyntez |
|
Russian Federation |
2020-06-26 |
2021-01-01 |
FAVPR-2020/I |
Phase 3 Clinical |
Status not specified |
21 |
6 Months |
200 |
|
2020-07-07 |
| A 3D Telemedicine During COVID-19: Non-clinical Validation |
Coronavirus disease 19 infection |
3D Telemedicine alone |
|
Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
NHS Greater Glasgow and Clyde |
Jean Brown Bequest Fund, Glasgow |
UK |
2020-07-31 |
2021-01-31 |
GN20HS287, NCT04444297 |
Phase Not Applicable |
Not yet recruiting |
1 |
6 Months |
40 |
|
2020-07-09 |
| Prevalence of Mental Health Problems Among Undergraduate Students at the Universidad de Los Andes |
Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression, Drug dependence, Suicidal ideation |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universidad de los Andes, Chile |
Ministerio de Educación, Chile |
Chile |
2020-08-03 |
2020-12-31 |
FDI UAN1901, NCT04447690 |
Phase Not Applicable |
Not yet recruiting |
1 |
4 Months |
3869 |
Francisco J Díaz Zenteno, MBBS, Francisco J Solorza Flores, MBBS, Gabriel A Lorca Osorio, MBBS, Jorge Gaete, Jorge Gaete Olivares, MD, PhD, José M Valdés Valdés, José M Valdés Valdés, BA, José M Valdés Valdés, MBBS, Matías Alvear Violic, MBBS, Pascale M Christiansen Barrio, MBBS |
2020-07-07 |
| Considering the administration of Desferral supplementary and Vitamin C on the ferritin levels of COVID-19 patients |
Coronavirus disease 19 infection, Viral infection |
desferal deodorant Baduz plus vitamin C |
|
|
Shahid Beheshti University of Medical Sciences, Laser Application in Medical Sciences Research Center |
|
Iran |
2020-02-20 |
|
IR.SBMU.RETECH.REC.1399.256, IRCT20190121042444N3 |
Phase 3 Clinical |
Recruiting |
1 |
|
78 |
Faranak Behnaz, Nahid Asadi, Seyed Ebrahim Sadeghzadeh Sadat |
2020-07-07 |
| A Phase I clinical trial of SARS-CoV-2 inactivated viral vaccine (COVID-19), Panacea Biotec/ Refana for the treatment of COVID-19 |
Coronavirus disease 19 infection |
SARS-CoV-2 inactivated viral vaccine (COVID-19), Panacea Biotec/ Refana alone |
|
|
Panacea Biotec Ltd |
|
|
2020-10-31 |
|
|
Phase 1 Clinical |
Planned |
0 |
|
|
|
2020-07-06 |
| The experiences of nurses hospitalized with novel coronavirus pneumonia (COVID-19) in China: a qualitative study Summary |
Coronavirus disease 19 infection, Viral pneumonia |
Interview using WeChat video alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Union Hospital Tongji Medical School Huazhong University Of Science & Technology |
|
China |
2020-05-27 |
2020-06-15 |
ChiCTR2000034433 |
Phase Not Applicable |
No longer recruiting |
1 |
|
15 |
Prof. Liu Yilan, Tan Xuan |
2020-07-07 |
| Novel coronavirus pneumonia (COVID-19) Prevention and Control Strategy - Development of multi-layer Network Early Warning System |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
Xinhua Hospital |
Chinesisch-Deutsches Zentrum fuer Wissenschaftsfoerderung |
China |
2020-10-01 |
2021-09-30 |
ChiCTR2000034359 |
Phase 0 Clinical |
Not yet recruiting |
1 |
12 Months |
6000 |
Yang Ling |
2020-07-07 |
| A clinical trial of plitidepsin for potential treatment of acute Respiratory Distress Syndrome (ARDS) in hospitalized COVID-19 pneumonia patients |
Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia |
plitidepsin alone |
Elongation factor 1 alpha 2 modulator, VEGF-1 receptor modulator |
|
Boryung Pharm Co Ltd |
|
South Korea |
2020-09-30 |
|
|
Phase Not Applicable |
Planned |
1 |
|
|
|
2020-07-06 |
| Plasma exchange in COVID-19 patients |
Coronavirus disease 19 infection, Inflammatory disease |
Variable regimens including colloidal solution (albumin and fresh frozen plasma) , convalescent plasma , plasma exchange |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Shahid Beheshti University of Medical Sciences, Laser Application in Medical Sciences Research Center |
|
Iran |
2020-06-21 |
|
IR.SBMU.MSP.REC.1399.118, IRCT20200416047099N2 |
Phase 2 Clinical |
Recruiting |
1 |
|
10 |
Abbas Hajifathali, Elham Roshandel, Haniye Ghaffari-nazari, Nasrin khateri |
2020-07-08 |
| A clinical trial of BNT-162a1 for potential treatment of COVID-19 infection |
Coronavirus disease 19 infection |
BNT-162a1 alone |
|
|
BioNTech SE, Pfizer Inc |
|
|
|
|
|
Phase 3 Clinical |
Planned |
0 |
|
30000 |
|
2020-07-06 |
| A multi-site clinical trial of COVID-19 vaccine for potential treatment of COVID-19 infection |
Coronavirus disease 19 infection |
COVID-19 vaccine alone |
|
|
Zydus Cadila Healthcare Ltd |
|
India |
|
|
|
Phase 2 Clinical |
Planned |
1 |
|
1000 |
|
2020-07-06 |
| A retrospective, case series study to illustrate [18F]-FDG-PET/CT findings in patients affected by cancer with clinical diagnosis of Covid-19 A retrospective study to illustrate [18F]-FDG-PET/CT findings in patients affected by cancer with clinical diagnosis of Covid-19 |
Coronavirus disease 19 infection |
PET/CT scan alone, [18F]-FDG alone |
|
|
Fondazione IRCCS Istituto Nazionale Tumori |
|
Italy |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
5 |
|
2020-07-06 |
| A clinical trial of StemVacs for potential treatment of COVID-19 infection |
Coronavirus disease 19 infection |
StemVacs, Emvolio alone |
|
|
Therapeutic Solutions International Inc |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-07-06 |
| ESPRIMO: Intervention for Young Adults With Multiple Sclerosis |
Coronavirus disease 19 infection, Multiple sclerosis, Psychiatric disorder |
ESPRIMO intervention alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Azienda Ospedaliera Universitaria Integrata Di Verona |
|
Italy |
2020-05-13 |
2022-08-31 |
2676CESC, ESPRIMO, NCT04431323 |
Phase Not Applicable |
Recruiting |
1 |
27 Months |
60 |
Alberto Gajofatto, Alberto Gajofatto Study Principal Investigator, Alberto Gajofatto, MD, PhD, Alina Klonova, Annamaria Ghellere, M.Sc., Doriana Rudi, Federico Schena, MD, PhD, Francesca Gobbin, MD, Francesca Vitali, PhD, Isolde M Busch, M.Sc., Lidia del Piccolo, PhD, Maria Angela Mazzi, PhD, Michela Rimondini, Michela Rimondini, PhD, Valeria Donisi, PhD |
2020-07-06 |
| RECOVER-19: Rehabilitation Needs and Functional Recovery in Covid-19 Acute and Post-acute Care |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universita Politecnica delle Marche |
|
Italy |
2020-07-01 |
2021-06-30 |
NCT04456036, NEUROREHABAN_COVID_2020, RECOVER-19 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
100 |
Elisa Andrenelli, MD PhD, Maria Gabriella Ceravolo, MD PhD, Marianna Capecci, Marianna Capecci, MD PhD |
2020-07-06 |
| COVIPLEX: Plasma exchange in severe COVID19 infection |
Coronavirus disease 19 infection |
OctaplasLG alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
University College London |
|
UK |
2020-06-25 |
|
132796, 2020-002668-29, COVIPLEX |
Phase 2 Clinical |
Recruiting |
1 |
|
40 |
|
2020-07-08 |
| Combined Endophthalmitis and Orbital Cellulitis in Patients With Novel Coronavirus Disease (COVID-19) |
Cellulitis, Coronavirus disease 19 infection, Endophthalmitis |
|
|
|
Minia University |
|
Egypt |
2020-04-27 |
2020-06-30 |
NCT04456556, OCULAR INFECTION IN COVID19 |
Phase Not Applicable |
Completed |
1 |
2 Months |
5 |
Mohamed Farouk Sayed Othman Abelkader |
2020-07-06 |
| Study on the Recovery of Pulmonary Function, Chest CT, Hematological and Immune and Inflammatory Conditions in COVID-19 Rehabilitation Patients |
Coronavirus disease 19 infection, Hematological disease, Immune disorder, Inflammatory disease, Pulmonary fibrosis |
lung CT imaging alone, lung function test alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Wuhan Union Hospital, China |
|
China |
2020-06-19 |
2022-06-01 |
NCIP03, NCT04456101 |
Phase Not Applicable |
Recruiting |
1 |
23 Months |
240 |
Juanjuan Xu, professor, Yang Jin, MD, Yang Jin, professor |
2020-07-16 |
| Intermediate-size, Expanded Access Program (EAP), Mesenchymal Stromal Cells (MSC) for Multisystem Inflammatory Syndrome in Children (MIS-C) Associated With Coronavirus Disease (COVID-19) |
Coronavirus disease 19 infection, Inflammatory disease |
Variable regimens including cetirizine , hydrocortisone , remestemcel-L |
Histamine H1 receptor antagonist |
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) |
Mesoblast International Sarl |
Mesoblast Ltd |
US |
|
|
MSB-MSC-MISC001, NCT04456439 |
Phase Not Applicable |
Recruiting |
1 |
|
50 |
Elizabeth Burke, ANP-C, Kenneth M. Borow, MD |
2020-07-13 |
| Illness Wellness Scale is a new scale which is being developed to assess the physical performance status of all patients, whether or not suffering from COVID infection, requiring surgical intervention or care |
Coronavirus disease 19 infection |
grading system alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
All India Institute of Medical Sciences |
|
India |
2020-07-11 |
|
CTRI/2020/07/026330 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
210 |
Dr Arun Kumar, Dr Yashwant Singh Rathore |
2020-07-08 |
| ConPlaS: Survey on Convalescent Plasma (CVP) for COVID-19 |
Coronavirus disease 19 infection |
Convalescent Plasma alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
All India Institute of Medical Sciences |
|
India |
2020-07-06 |
|
CTRI/2020/07/026331, ConPlaS |
Phase Not Applicable |
Not yet recruiting |
1 |
|
2200 |
Diptiranjan Rout |
2020-07-08 |
| A first-in-human clinical study to assess safety and tolerability of niclosamide in healthy subjects for the treatment of COVID-19 |
Coronavirus disease 19 infection |
niclosamide (COVID-19), UNION therapeutics/ Institut Pasteur Korea alone |
S phase kinase associated protein 2 inhibitor |
Healthy volunteers accepted |
UNION therapeutics |
Denmark Technical University, The Danish National Advanced Technology Foundation, Trial Nation Denmark |
Denmark |
|
|
|
Phase Not Applicable |
Not yet recruiting |
2 |
|
|
|
2020-07-03 |
| Whole-virion Inactivated SARS-CoV-2 Vaccine (BBV-152) for COVID-19 in Healthy Volunteers (BBV-152) |
Coronavirus disease 19 infection |
COVAXIN alone |
COVID19 Spike glycoprotein modulator |
Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Bharat Biotech International Ltd |
Indian Council of Medical Research |
India |
2020-07-13 |
2021-06-30 |
BBIL/BBV152-A/2020, CTRI/2020/07/026300, NCT04471519 |
Phase 1/Phase 2 Clinical |
Recruiting |
12 |
11 Months |
1125 |
Dr Ajeet Pratap Singh, Dr Amit Suresh Bhate, Dr Chandramani Singh, Dr Chandrasekhar Gillurkar, Dr Jitendra Kushwaha, Dr Prabhakar Reddy, Dr Prabhakar Reddy, MD, Dr R Vasudev, Dr Sagar Vivek Redkar, Dr Sanjay Kumar Rai, Dr Satyajit Mohapatra, Dr Savita Verma, Dr Savita Verma, MD, Dr Venkata rao, Dr. Ajeeth Pratap Singh, MBBS, MD, Dr. Amit Bhate, MBBS, MD, Dr. Chadrashekar Gillukar, MBBS, MD, Dr. Chandramani Singh, MBBS, MD, Dr. Jitendra Kushwaha, MBBS, MD, Dr. Prabhakar Reddy, MBBS, MD, Dr. Rajapantula Vasudev, MBBS, MD, Dr. Sagar Vivek Redkar, MBBS, MD, Dr. Sanjay Kumar Rai, MBBS, MD, Dr. Satyajit Mohapatra, MBBS, MD, Dr. Savita Verma, MBBS, MD, Dr. V Krishna Mohan, PhD, Dr. Venkata Rao, MBBS, MD |
2020-07-16 |
| A phase I trial of COVAXIN for COVID-19 |
Coronavirus disease 19 infection |
COVAXIN alone |
COVID19 Spike glycoprotein modulator |
|
Bharat Biotech International Ltd |
Indian Council of Medical Research, National Institute of Virology |
India |
2020-07-31 |
|
|
Phase 1 Clinical |
Planned |
1 |
|
|
|
2020-07-10 |
| A Phase III trial of COVID-19 vaccine for COVID-19 patients |
Coronavirus disease 19 infection |
COVID-19 vaccine (inactivated, Vero cells/intramuscular), Beijing Biological Products Institute/National Institute for Viral Disease Control and Prevention of Chinese Center for Disease Control and Prevention alone |
|
|
Sinopharm China National Biotech Institute Co Ltd |
|
United Arab Emirates |
|
|
|
Phase 3 Clinical |
Planned |
1 |
|
|
|
2020-07-03 |
| Atovaquone for Treatment of COVID-19 |
Coronavirus disease 19 infection |
atovaquone alone, standard of care therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Texas Southwestern Medical Center |
|
US |
2020-07-31 |
2021-03-31 |
NCT04456153, STU-2020-0707 |
Phase 2 Clinical |
Not yet recruiting |
1 |
8 Months |
60 |
Hesham Sadek, M.D., Mamta Jain, Mamta Jain, M.D., Tianna Petersen |
2020-07-14 |
| A phase IIb/III, global clinical study to assess BNT-162a1, BNT-162b1, BNT-162b2 and BNT-162c2 in healthy subjects |
Coronavirus disease 19 infection |
BNT-162a1 alone, BNT-162b1 alone, BNT-162b2 alone, BNT-162c2 alone |
COVID19 Spike glycoprotein modulator |
Healthy volunteers accepted |
BioNTech SE, Pfizer Inc |
|
|
2020-07-31 |
|
|
Phase 2/Phase 3 Clinical |
Planned |
0 |
|
30000 |
|
2020-07-16 |
| A trial to evaluate MV-014-210 for the prevention of coronavirus infection |
Coronavirus disease 19 infection |
MV-014-210 alone |
COVID19 Spike glycoprotein modulator |
|
Meissa Vaccines Inc |
|
US |
|
|
|
Phase Not Applicable |
Planned |
1 |
|
|
|
2020-07-08 |
| A multicenter, randomized, double-blind, placebo-controlled, phase III clinical trial protocol to evaluate the safety and efficacy of siltuximab plus standard-of-care in hospitalized patients (expected n = 400) with COVID-19 associated ARDS |
Coronavirus disease 19 infection, Respiratory distress syndrome |
siltuximab alone, standard of care alone |
Heat shock protein inhibitor, IL-6 receptor antagonist |
|
EUSA Pharma |
|
|
|
|
|
Phase 3 Clinical |
Not yet recruiting |
0 |
|
400 |
|
2020-07-03 |
| Characteristics of Patients and Healthcare Workers With COVID-19 in Meta State, Colombia |
Coronavirus disease 19 infection, Respiratory disease |
standard care alone |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Departamental De Villavicencio |
Clínica Meta, Grupo de Investigación de Villavicencio, Spring Medical Clinic, Universidad Cooperativa De Colombia |
Colombia |
2020-07-31 |
2020-08-31 |
GRIVI-2020-01COVID, NCT04456426 |
Phase Not Applicable |
Not yet recruiting |
1 |
1 Month |
250 |
Emma I Rodríguez, MSc, Norton Perez, Norton Perez, MD |
2020-07-06 |
| A clinical study of OPN-019 for the potential treatment of COVID-19 infection |
Coronavirus disease 19 infection |
OPN-019 alone |
|
|
Optinose US Inc |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-07-10 |
| PROFISCOV: Clinical Trial of Efficacy and Safety of Sinovac's Adsorbed COVID-19 (Inactivated) Vaccine in Healthcare Professionals |
Coronavirus disease 19 infection |
CoronaVac alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Instituto Butantan, Sinovac Biotech Ltd |
Sinovac Life Sciences Co., Ltd. |
Brazil |
2020-07-31 |
2021-10-31 |
COV-02-IB, NCT04456595, PROFISCOV |
Phase 3 Clinical |
Not yet recruiting |
12 |
15 Months |
8870 |
André Siqueira, MD, PhD, Eduardo B Coelho, MD, PhD, Eduardo B Coelho, MD,PhD, Esper Kallas, MD,PhD, Fabiano Ramos, MD, Francisco H Aoki, MD, PhD, Fábio E Leal, MD, PhD, Gustavo Adolfo Sierra Romero, MD, PhD, Luis Fernando Aranha Camargo, MD, PhD, Luiz Carlos Pereira Júnior, MD, PhD, Mauro M Teixeira, MD, PhD, Maurício L Nogueira, MD, PhD, PhD, Ricardo Palacios, MD, PhD, Sonia Raboni, MD, PhD |
2020-07-08 |
| INFECT-19: Inflammatory Regulation Effect of NAC on COVID-19 Treatment |
Coronavirus disease 19 infection, Inflammatory disease |
N-acetylcysteine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
King Saud University |
|
Saudi Arabia |
2020-08-01 |
2021-08-30 |
E-20-4934, INFECT-19, NCT04455243 |
Phase 3 Clinical |
Not yet recruiting |
1 |
12 Months |
1180 |
Dr. Tariq Alhawassi, Soundus Atta, PH |
2020-07-06 |
| CARDOVID: Cardiac and Thoracic Imaging in Pediatric Patients With Evidence of Systemic Inflammation COVID-19 Linked |
Cardiogenic shock, Coronavirus disease 19 infection, Inflammatory disease, Myocarditis |
CT scan alone, MRI alone |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Imagine Institute |
|
France |
2020-06-15 |
2022-06-30 |
CARDOVID, HJ-20-CARDOVID, NCT04455347 |
Phase Not Applicable |
Recruiting |
1 |
24 Months |
80 |
Francesca Raimondi |
2020-07-06 |
| Lopinavir/Ritonavir for the Treatment of COVID-19 Positive Patients With Cancer and Immune Suppression in the Last Year |
Coronavirus disease 19 infection |
lopinavir + ritonavir alone |
HIV protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
OHSU Knight Cancer Institute |
National Cancer Institute, Oregon Health Sciences University |
US |
2020-07-06 |
2021-07-01 |
NCI-2020-02877, NCT04455958, P30CA069533, STUDY00021444 |
Phase 2 Clinical |
Not yet recruiting |
1 |
11 Months |
75 |
Raymond C Bergan, Raymond C. Bergan |
2020-07-06 |
| ECCES: COVID-19 and Chilblains |
Coronavirus disease 19 infection |
biological sampling alone |
|
Healthy volunteers accepted |
Rennes University Hospital |
|
France |
2020-07-15 |
2020-09-30 |
35RC20-8888-ECCES, ECCES, NCT04455308 |
Phase Not Applicable |
Not yet recruiting |
5 |
2 Months |
300 |
Alain DUPUY, MD, PhD, Emilie BRENAUT, MD, Mahtab SAMIMI, MD, PhD, Sébastien BARBAROT, MD, PhD, Yannick Le Corre, MD |
2020-07-06 |
| Use of Mesenchymal Stem Cells in Acute Respiratory Distress Syndrome Caused by COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia |
Wharton's jelly derived mesenchymal stem cell therapy (iv, ARDS caused by COVID-19), Instituto de Medicina Regenerativa alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Instituto de Medicina Regenerativa |
|
Mexico |
2020-04-16 |
2020-09-15 |
MSC-ARDS-001, NCT04456361 |
Phase 0 Clinical |
No longer recruiting |
1 |
5 Months |
9 |
Jesus Perez |
2020-07-09 |
| A phase I clinical trial of GC-376 for the treatment of patients with COVID-19 infection |
Coronavirus disease 19 infection |
GC-376 alone |
COVID19 replicase polyprotein 1a inhibitor, COVID19 replicase polyprotein 1ab inhibitor |
|
Anivive Lifesciences Inc |
|
|
2020-12-31 |
|
|
Phase 1 Clinical |
Planned |
0 |
|
|
|
2020-07-03 |
| Convalescent Plasma as Treatment for Subjects With Early COVID-19 Infection |
Coronavirus disease 19 infection |
convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hackensack Meridian Health |
|
US |
2020-07-31 |
2021-07-31 |
NCT04456413, PRO2020-0542 |
Phase 2 Clinical |
Not yet recruiting |
1 |
12 Months |
306 |
Mariefel Vendivil, Marlo Kemp, Michele L Donato, MD |
2020-07-06 |
| Risk Prediction and Therapy Monitoring in Patients With SARS-Cov-2 Infection/COVID 19 |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Heidelberg |
|
Germany |
2020-04-01 |
2022-04-30 |
CROWNLESS, NCT04456075 |
Phase Not Applicable |
Recruiting |
1 |
25 Months |
100 |
Felix JF Herth, MD, Frederik Trinkmann, MD |
2020-07-06 |
| SPIKE-1: A Trial Looking at the Use of Camostat to Reduce Progression of Symptoms of Coronavirus (COVID-19) in People Who Have Tested Positive But Are Able to Stay at Home |
Coronavirus disease 19 infection |
repurposed camostat (COVID-19), University of Tokyo alone |
Serine protease inhibitor, Trypsin inhibitor |
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cancer Research UK, University of Edinburgh |
Latus Therapeutics, LifeArc, Ono Pharmaceutical Co Ltd |
UK |
2020-07-27 |
2021-08-31 |
2020-002110-41, CRUKD/20/002, NCT04455815, SPIKE-1 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
2 |
13 Months |
389 |
Centre for Drug Development, Kevin Dhaliwal, Professor, Suzie Anthony, Dr |
2020-07-20 |
| German Covid-19 ICU Registry |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Tubingen |
|
Germany |
2020-07-31 |
2021-12-31 |
DCIR, NCT04455451 |
Phase Not Applicable |
Not yet recruiting |
1 |
17 Months |
2000 |
Harry Magunia, MD, Peter Rosenberger, MD, PhD |
2020-07-06 |
| CANADA: Inhaled NO for the Treatment of COVID-19 Caused by SARS-CoV-2 |
Coronavirus disease 19 infection, Dyspnea |
LungFit system alone, nitric oxide alone, standard supportive care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Beyond Air Ltd |
|
|
2020-07-15 |
2020-12-15 |
BAI_COV19_01_CAN, CANADA, NCT04456088 |
Phase 2 Clinical |
Not yet recruiting |
0 |
5 Months |
50 |
Asher Tal, MD, Meital Hatan, Rinat Kalaora |
2020-07-06 |
| COVID_ENZA: Randomized, Open-Label, Phase II Study to Evaluate the Efficacy of Enzalutamide in High-Risk Male Outpatients With COVID-19 |
Coronavirus disease 19 infection |
enzalutamide alone, standard of care alone |
Androgen receptor antagonist, Cytochrome P450 3A4 stimulator, DNA binding protein inhibitor, Prostate specific antigen modulator, Translocation associated protein inhibitor |
Male, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Osped Italiano |
Institute For Research In Biomedicine, Institute of Oncology Research (Switzerland), Oncology Institute of Southern Switzerland |
Switzerland |
2020-07-31 |
2021-12-31 |
COVID_ENZA, COVID_ENZA, NCT04456049 |
Phase 2 Clinical |
Not yet recruiting |
1 |
17 Months |
90 |
Ricardo Pereira Mestre, Ricardo Pereira Mestre, MD |
2020-07-06 |
| CoV2_LapSurg: Can the COVID-19 virus be detected in the smoke generated in minimally invasive surgery in patients with confirmed coronavirus infection? |
Coronavirus disease 19 infection |
Biosampler (SKC Inc, AMS Analitica) alone, RT-PCR alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Azienda Unita Sanitaria Locale di Reggio Emilia |
|
Italy |
2020-04-23 |
2021-06-24 |
600/2020/OSS/AUSLRE, CoV2_LapSurg, ISRCTN18077365 |
Phase Not Applicable |
Recruiting |
1 |
14 Months |
20 |
Dr Maurizio Zizzo, Dr Ruggero Bollino |
2020-07-06 |
| NutriCoronaTeen: Lifestyle modification of adolescents from different countries during confinement by Covid-19 |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Fundación Imdea Alimentación |
|
Spain, Italy, Colombia, Brazil, Chile |
2020-04-09 |
2020-06-19 |
IMD PI-043, ISRCTN14025343, NutriCoronaTeen |
Phase Not Applicable |
Completed |
5 |
2 Months |
500 |
Dr Alberto Davalos, Dr María B. Ruiz-Roso |
2020-07-13 |
| Study of Ampion for the Treatment of Adult COVID-19 Patients Requiring Oxygen Supplementation |
Coronavirus disease 19 infection |
Ampion alone, Standard of care alone |
Aryl hydrocarbon receptor agonist, Stem cell antigen-1 inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ampio Pharmaceuticals Inc |
|
US |
2020-07-25 |
2020-11-15 |
AP-016, NCT04456452 |
Phase 1 Clinical |
Not yet recruiting |
1 |
3 Months |
10 |
|
2020-07-16 |
| Qualitative Study on Self-protection Experience of Medical Staff in the Isolation Area of Novel Coronavirus Pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Self-protection alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Guangdong Provincial Hospital of Chinese Medicine |
|
China |
2020-04-09 |
2020-06-15 |
ChiCTR2000034287 |
Phase Not Applicable |
No longer recruiting |
1 |
2 Months |
11 |
Lu Peng |
2020-07-07 |
| SARS-CoV2-School Student Study: Prevalence of SARS-CoV2 in scholars: comparison of boarding and private school (COVID-19) |
Coronavirus disease 19 infection |
throat swab and a blood sample alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Landessportverband Baden-Württemberg e. V. (LSV) |
|
Germany |
2020-05-27 |
|
280/20, DRKS00021909, SARS-CoV2-School Student Study |
Phase Not Applicable |
Recruiting |
1 |
|
60 |
Heidrun Zurmöhle, Peter Deibert |
2020-07-08 |
| COVAPEX: COVID-19 in ART: Perception and Experience |
Coronavirus disease 19 infection, Female infertility, Male infertility |
assisted reproductive treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
University Hospital, Montpellier |
|
France |
2020-06-01 |
2020-07-30 |
COVAPEX, NCT04456010, RECHMPL20_0351 |
Phase Not Applicable |
Recruiting |
1 |
1 Month |
600 |
Noémie RANISAVLJEVIC, M.D., Ph.D, Noémie Ranisavljevic, M.D., Ph.D |
2020-07-08 |
| MANFFT-02: Safety and tolerance of manuka honey for use as a nebulizer solution |
Coronavirus disease 19 infection |
makula honey alone, nebulizer alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Manukamed Ltd |
University of Waikato |
New Zealand |
2020-07-13 |
2020-09-28 |
ACTRN12620000701921p, MANFFT-02 |
Phase 1 Clinical |
Not yet recruiting |
1 |
2 Months |
15 |
Dr Chris McMahon |
2020-07-07 |
| Fit testing of N95 filtering facepieces for anesthetists and nurses treating COVID-19 patients |
Coronavirus disease 19 infection |
N95 FFP alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Austin Health |
|
Australia |
2020-06-29 |
|
ACTRN12620000702910, U1111-1253-8286 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
60 |
A/Prof Laurence Weinberg, Dr Caitlin Low |
2020-07-07 |
| Laryngectomy during COVID-19 |
Coronavirus disease 19 infection |
laryngectomy alone |
|
|
Melaka Hospital |
|
Malaysia |
2020-07-01 |
2021-06-30 |
55502, NMRR-20-1249-55502 |
Phase Not Applicable |
Status not specified |
1 |
12 Months |
|
Dr MOHAMED ILIYAS BIN SULTAN ABDUL KADER |
2020-07-07 |
| Healthcare workers knowledge, perception and compliance to PPE |
Coronavirus disease 19 infection |
personal protective equipment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universiti Teknologi Mara |
|
Malaysia |
2020-08-01 |
2021-03-31 |
55226, NMRR-20-1241-55226 |
Phase Not Applicable |
Not yet recruiting |
2 |
8 Months |
323 |
Dr Nurul Huda Ahmad |
2020-07-07 |
| A Placebo-Controlled Study to Evaluate the effect of the recombinant Bacillus Calmette–Guérin (BCG) vaccine VPM-1002 on the Incidence or Disease Severity of SARS-COV-2/COVID-19 Among High-Risk Participants in Australia |
Coronavirus disease 19 infection |
VPM-1002 alone |
Listeriolysin stimulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
ACCELAGEN PTY LTD, Serum Institute of India Ltd |
|
Australia |
2020-06-30 |
2021-03-30 |
ACTRN12620000707965 |
Phase 3 Clinical |
Not yet recruiting |
1 |
9 Months |
3468 |
A/Prof Mark Bloch, Mr Greg Plunkett |
2020-07-07 |
| KAP TandCM: KAP TandCM |
Coronavirus disease 19 infection |
|
|
|
Ministry of Health, Malaysia |
|
Malaysia |
2020-07-06 |
2020-08-10 |
55387, KAP TandCM, NMRR-20-1240-55387 |
Phase Not Applicable |
Not yet recruiting |
1 |
1 Month |
|
none TEH LI YIN |
2020-07-07 |
| Telepharmacy, Counseling, Covid-19 |
Coronavirus disease 19 infection |
|
|
|
Hospital Sungai Buloh |
|
Malaysia |
2020-04-20 |
2020-06-18 |
55573, NMRR-20-1278-55573 |
Phase Not Applicable |
Status not specified |
1 |
1 Month |
|
MS KALAIVANI A/P SUBRAMANIAM |
2020-07-07 |
| Warning Signs in COVID-19 Patients |
Coronavirus disease 19 infection |
|
|
|
Hospital Sungai Buloh |
|
Malaysia |
2020-08-01 |
2021-08-01 |
55360, NMRR-20-1237-55360 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
|
Doctor DR Yasmin Mohamed Gani, Dr Syarifah Nurul Ain Bt Syed Badaruddin |
2020-07-07 |
| Effectiveness of Convalescent Immune Plasma Therapy |
Coronavirus disease 19 infection |
Convalescent Immune Plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Bağcılar Training & Research Hospital |
|
Turkey |
2020-05-15 |
2020-06-17 |
2020.05.2.14.070, NCT04442958 |
Phase Not Applicable |
Completed |
1 |
1 Month |
60 |
Salih SS Sevdi, Md |
2020-07-07 |
| Effects of Online and Recovery-oriented Peer Support Groups Facilitated by Peer Support Workers in Times of COVID-19 |
Anxiety disorder, Coronavirus disease 19 infection, Mood disorder, Psychotic disorder, Schizophrenia |
Transitional Online Peer Support alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre de recherche de l'Institut universitaire en santé mentale de Québec |
Yale University |
Canada |
2020-07-31 |
2020-10-31 |
2021-2281, NCT04445324 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
48 |
Jean-Francois Pelletier, PhD |
2020-07-20 |
| Psychosocial impact of COVID-19 pandemic on health care workers in a tertiary care hospital in MY |
Coronavirus disease 19 infection |
|
|
|
Sarawak General Hospital |
|
Malaysia |
2020-06-25 |
2020-07-31 |
55333, NMRR-20-1271-55333 |
Phase Not Applicable |
Status not specified |
1 |
1 Month |
|
Chuah Jun Sen |
2020-07-07 |
| Stellate Ganglion Blockade in COVID-19 Positive Patients |
Adult respiratory distress syndrome, Coronavirus disease 19 infection |
Stellate Ganglion Block alone, Variable regimens including Decadron , bupivacaine, AstraZeneca , clonidine |
Sodium channel inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Nebraska |
|
|
2020-07-31 |
2021-07-31 |
603.20.FB, NCT04445337 |
Phase Not Applicable |
Not yet recruiting |
0 |
12 Months |
10 |
|
2020-07-07 |
| Effect of Physical Therapy Exercises on Cardiorespiratory Fitness Level in COVID19 Patients After Recovery |
Coronavirus disease 19 infection |
aerobic training alone, breathing exerises alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Government College University Faisalabad |
|
Pakistan |
2020-07-03 |
2020-08-15 |
313, NCT04445376 |
Phase Not Applicable |
Recruiting |
2 |
1 Month |
20 |
Awais Bin Inam, Phd., Ishtiaq Ahmed, Ishtiaq Ahmed, DPT, ishtiaq ahmed |
2020-07-10 |
| FeelGood: Psychological Impact of Admission With Covid-19 During the SARS-CoV-2 Pandemic: Clinical Trial of a Digital Intervention to Improve Wellbeing |
Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder |
Feeling Good Digital App alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Royal Free Hospital NHS Foundation Trust |
|
UK |
2020-06-21 |
2020-12-31 |
FeelGood, NCT04449627, ROYALFREENHS |
Phase Not Applicable |
Not yet recruiting |
1 |
6 Months |
58 |
Joanna Dobbin, MScMBBS, Research and Development Manager |
2020-07-20 |
| Ivermectin in the prevention of covid-19 |
Coronavirus disease 19 infection, Respiratory tract infection |
ivermectin alone |
Chloride channel modulator |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
DVFM |
|
India |
2020-07-10 |
|
CTRI/2020/06/026232 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
50 |
BKumar |
2020-07-13 |
| To study effect of ayurvedic treatment for prevention and management of asymptomatic, mild and moderate cases of COVID-19 |
Coronavirus disease 19 infection |
standard of care alone, Variable regimens including Samshamanivati , SitopaladiChurna , Sutshekhar , TribhuvanKirti , black resins , cardamom , cinnamon , ginger , pepper , shunthiksheerpak , turmeric |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Ministry of Ayush |
SYMBIOSIS INSTITUTE OF HEALTH SCIENCE |
India |
2020-07-15 |
|
CTRI/2020/06/026231 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
160 |
Dr Jyoti Shirodkar, Dr Rajkumar Nikalje |
2020-07-07 |
| CASCADE: Measures of Complement Activation and Inflammation in Patients With COVID-19 |
Coronavirus disease 19 infection, Inflammatory disease, Respiratory failure |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Portsmouth Hospitals NHS Trust |
Akari Therapeutics Plc |
UK |
2020-05-28 |
2021-09-30 |
CASCADE, NCT04453527, PHT/2020/37 |
Phase Not Applicable |
Recruiting |
1 |
16 Months |
100 |
Anoop J Chauhan, Anoop J Chauhan, PhD |
2020-07-06 |
| Neuropathology in Adults Intensive Care Unit Patients With COVID-19 |
Brain injury, Coronavirus disease 19 infection |
autopsy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universite De Versailles-St Quentin En Yvelines |
|
France |
2020-03-10 |
2020-05-15 |
NCT04453670, OBS2020 |
Phase Not Applicable |
Completed |
1 |
2 Months |
7 |
Djillali Annane, Djillali annane |
2020-07-04 |
| CHAT: The California Home Abortion by Telehealth (CHAT) Study |
Abortion, Coronavirus disease 19 infection |
counseling alone, mifepristone alone, telehealth consultation alone |
Estradiol 17 beta dehydrogenase stimulator, Glucocorticoid receptor antagonist, Progesterone receptor antagonist |
Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of California San Francisco |
California Latinas for Reproductive Justice, UCGHI Women's Health, Gender, and Empowerment Center of Expertise |
US |
2020-11-30 |
2022-10-31 |
19-29437, CHAT, NCT04432792 |
Phase 2 Clinical |
Not yet recruiting |
1 |
23 Months |
700 |
Karen Meckstroth, MD, Ushma Upadhyay, PhD, MPH |
2020-07-08 |
| A clinical trial of Ayurveda formulations in COVID-19 |
Coronavirus disease 19 infection |
Variable regimens including Ashtadashang Ghana Vati , Malla Chandrodaya , Parijata swaras |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Banaras Hindu University |
Ministry of Ayush |
India |
2020-07-10 |
|
CTRI/2020/06/026229 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
100 |
Dr Namrata Joshi |
2020-07-07 |
| A Study on Unani regimen for prevention of high/moderate risk population of COVID 19 |
Coronavirus disease 19 infection |
Khameera Marwareed alone, Tiryaq-e-Arba alone, Variable regimens including Behidana (Cydonia oblonga) , Sapistan (Cordia myxa) , Unnab (Zizyphus jujube) |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Central Council for Research in Unani Medicine |
|
India |
2020-07-07 |
|
CCRUM 04/06/2020/, CTRI/2020/06/026227 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
60 |
Dr Naheed Parveen, Dr Pradeep Kumar, Prof Asim Ali Khan |
2020-07-07 |
| Study to Evaluate STI-1499 (COVI-GUARD) in Hospitalized Patients With COVID-19 |
Coronavirus disease 19 infection, Lung infection |
COVI-GUARD alone, standard of care alone |
COVID19 Spike glycoprotein inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sorrento Therapeutics Inc |
|
|
2020-08-31 |
2021-01-31 |
NCT04454398, STI-1499-1001 |
Phase 1 Clinical |
Not yet recruiting |
0 |
5 Months |
24 |
Andreas G Niethammer, MD PhD, Ying Yan |
2020-07-04 |
| FAP-REA: FilmArray and Management of ICU Patients With Pneumonia in the Covid-19 Context |
Coronavirus disease 19 infection, Respiratory disease, Viral pneumonia |
FilmArray alone, PCR test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Central Hospital, Nancy, France |
Centre Hospitalier Universitaire de Reims |
|
2020-07-01 |
2020-08-30 |
2020PI101, FAP-REA, NCT04453540 |
Phase Not Applicable |
Not yet recruiting |
0 |
1 Month |
150 |
|
2020-07-04 |
| Tele-Wellness Supported App for Family Child Care Home Providers and Families to Promote Health, Family Engagement, and School Readiness Amid COVID-19 |
Acute stress disorder, Coronavirus disease 19 infection |
family child care home (FCCH) alone |
|
Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Johns Hopkins University |
|
US |
2020-07-31 |
2021-07-31 |
IRB00250864, NCT04453657 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
270 |
Kimberly Hill, MS, Lucine Francis, PhD |
2020-07-10 |
| Hexoskin Feasibility Study With COVID-19 Patients |
Coronavirus disease 19 infection |
Hexoskin smart shirt alone |
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hexoskin |
|
Canada |
2020-07-15 |
2020-12-15 |
HEXOSKIN COVID-19 STUDY, NCT04453891 |
Phase Not Applicable |
Not yet recruiting |
1 |
5 Months |
16 |
Maria Strifas Athanassiou, MSc, Nguyen Thu Ngan Trinh, Nguyen Thu Ngan Trinh, PhD |
2020-07-04 |
| Bariatric Surgery During Lockdown, Impact of COVID-19 on Physical and Mental Health |
Coronavirus disease 19 infection, Obesity |
bariatric surgery alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
University of Rome Tor Vergata |
|
Italy |
2020-03-09 |
2020-05-30 |
NCT04453579, UNROMEB |
Phase Not Applicable |
Completed |
1 |
2 Months |
116 |
paolo gentileschi, MD |
2020-07-03 |
| Delay study COVID Kuching |
Coronavirus disease 19 infection |
|
|
|
PEJABAT KESIHATAN BAHAGIAN KUCHING |
|
Malaysia |
2020-06-30 |
2020-07-31 |
55365, NMRR-20-1299-55365 |
Phase Not Applicable |
No longer recruiting |
1 |
1 Month |
|
Dr Andrew Kiyu, Dr MICHEAL PELITINI ANAK UGAK, doctor GREGORY A/L JOSEPH XAVIER |
2020-07-07 |
| Monovalent Recombinant COVID19 Vaccine (COVAX-19) |
Coronavirus disease 19 infection |
Covax-19 alone |
Coronavirus spike glycoprotein inhibitor |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Vaxine Pty Ltd |
Central Adelaide Local Health Network Inc |
Australia |
2020-06-30 |
2021-07-01 |
13110, NCT04453852 |
Phase 1 Clinical |
Recruiting |
1 |
12 Months |
40 |
David Gordon, MBBS, Ph.D, David Gordon, MBBS, PhD, Guy Ludbrook, MBBS, Kathy Heyman, Nikolai Petrovsky, MBBS, Ph.D, Pravin Hissaria, MBBS. PhD |
2020-07-10 |
| AtTAC: Impact of Tissue Plasminogen Activator (tPA) Treatment for an Atypical Acute Respiratory Distress Syndrome (COVID-19) |
Coronavirus disease 19 infection, Lung embolism, Respiratory distress syndrome, Respiratory failure |
Variable regimens including alteplase , heparin , low molecular weight heparin , unfractionated heparin |
Tissue plasminogen activator stimulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Negovsky Research Institute of General Reanimatology |
Sklifosovsky Institute of Emergency Care |
|
2020-07-01 |
2020-11-01 |
AtTAC, NCT04453371, TPA-2020 |
Phase 3 Clinical |
Not yet recruiting |
0 |
4 Months |
50 |
Valery Likhvantsev |
2020-07-04 |
| Examining COVID-19 death cases in Kuching Sarawak. A public health case-control study |
Coronavirus disease 19 infection |
|
|
|
PEJABAT KESIHATAN BAHAGIAN KUCHING |
|
Malaysia |
2020-06-30 |
2020-07-31 |
55371, NMRR-20-1287-55371 |
Phase Not Applicable |
Status not specified |
1 |
1 Month |
|
Dr Andrew Kiyu, Dr MICHEAL PELITINI ANAK UGAK v, doctor GREGORY A/L JOSEPH XAVIER |
2020-07-06 |
| AZITHROVID: Anti Infective Agents Impact in COVID-19 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
azithromycin alone, azithromycin plus hydroxychloroquine |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre d'Investigation Clinique et Technologique 805 |
|
France |
2020-03-02 |
2020-04-25 |
AZITHROVID, AZITHROVID, INDS, NCT04453501 |
Phase Not Applicable |
Completed |
1 |
1 Month |
132 |
|
2020-07-03 |
| SARSCoV2CZImun: Antibody Detection in COVID-19 Cured Patients (SARS-CoV-2-CZ-Immunity) |
Coronavirus disease 19 infection |
SARS-CoV-2 diagnostic rapid test alone, blood sampling alone |
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Institute of health information and statistics of the Czech Republic |
Institut Klinické a Experimentální Medicin, MasaryKuv Onkologicky Ustav, Masaryk University, Ministry of Health, Czech Republic, National Institute of Public Health, Prague, St. Anne's University Hospital Brno, Czech Republic, University Hospital Brno |
Czech Republic |
2020-05-18 |
2020-06-03 |
NCT04453280, SARSCoV2CZImun, UZIS 2020/2 |
Phase Not Applicable |
Completed |
1 |
|
695 |
Dalibor Valík, Prof., Jarmila Razova, M.D., Ph.D., Ladislav Dusek, Prof., Roman Prymula, Prof. |
2020-07-03 |
| POLYCOR: Study to Evaluate the Safety and Efficacy of XAV-19 in Patients With COVID-19 Induced Moderate Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
XAV-19 alone |
COVID19 Spike glycoprotein inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
CHU De Nantes, Xenothera |
Bpifrance |
France |
2020-07-06 |
2021-09-30 |
NCT04453384, POLYCOR, RC20_0230 |
Phase 2 Clinical |
Not yet recruiting |
4 |
14 Months |
368 |
Benjamin GABORIT, Florence ADER, François RAFFI, Karine LACOMBE, Vincent DUBEE |
2020-07-03 |
| Is COVID-19 Transmitted Through Human Milk? Implications for Breastfeeding and Human Milk Banking-Study 1a |
Coronavirus disease 19 infection |
breastmilk sampling alone |
|
Healthy volunteers accepted |
Hospital for Sick Children |
Sinai Health System, University of Toronto |
Canada |
2020-05-24 |
2021-01-31 |
39373-A, NCT04453969 |
Phase Not Applicable |
Recruiting |
2 |
8 Months |
50 |
Deborah L O'Connor, PhD RD, Deborah O'Connor, Sharon Unger, MD |
2020-07-03 |
| The Assessment of the Prevalence, Clinical Course and Treatment of COVID-19 Complications |
Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder |
complex diagnostic panel alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Silesian Center for Heart Diseases |
Slaski Uniwersytet Medyczny w Katowicach |
Poland |
2020-06-08 |
2021-11-30 |
COVID-19 COMPLICATIONS STUDY, NCT04453748 |
Phase Not Applicable |
Recruiting |
1 |
17 Months |
200 |
Mariusz Gasior |
2020-07-07 |
| Clinical Characteristics and Outcomes of 187 Critically Ill Patients With Coronavirus Disease 2019 (COVID-19) |
Coronavirus disease 19 infection |
corticosteroid therapy alone, heparin alone, hydroxychloroquine alone, tocilizumab alone |
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Sao Domingos |
|
Brazil |
2020-07-15 |
2020-11-30 |
COVID-19 ICU, NCT04454372 |
Phase Not Applicable |
Not yet recruiting |
1 |
4 Months |
187 |
JOSE AZEVEDO, MD, JOSE R AZEVEDO, MD, PhD, José Raimundo Araujo de Azevedo |
2020-07-03 |
| At Home Monitoring for Patients With Covid-19 |
Coronavirus disease 19 infection |
Covidfreeathome app alone, pulse oximeter alone, smart watch alone, thermometer alone |
|
|
The University Health Network |
Sunnybrook Health Sciences Centre, University of Toronto |
Canada |
2020-07-07 |
2023-04-30 |
3185, NCT04453774 |
Phase Not Applicable |
Not yet recruiting |
2 |
33 Months |
1000 |
Robert Wu, Tatiana Son |
2020-07-08 |