Last updated: Aug 01, 2020 - 02:00 BST

Title Indication Intervention Actions PatientSelection Sponsor Collaborator Country StartDate EndDate Identifiers Phase Recruitment Status Sites Trial Duration Enrollment Count Contacts LastChanged
Knowledge, Attitudes, and Practices Towards COVID-19 Among Health Care Professionals Among Healthcare Professionals Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Istinye Universitesi Turkey 2020-08-01 2020-12-10 00010, NCT04492202 Phase Not Applicable Not yet recruiting 0 4 Months 200 Aysegul Asalioglu, Yasemin ÇIRAK, Assoc. Prof. 2020-07-31
Ayurveda strength and immunity enhancing protocol and immunity in health care workers : clinical trial of an Ayurveda Intervention Coronavirus disease 19 infection AYUSH Kadha alone, Anu taila alone, Chyavanprash alone, Pranayama alone, Shanshamni Vati alone, Yoga alone, rock salt alone, turmeric alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) All India Institute of Ayurveda India 2020-07-28 CTRI/2020/07/026756 Phase Not Applicable Not yet recruiting 1 425 Dr Santosh Kumar Bhatted, Dr Tanuja Manoj Nesari 2020-07-31
Clinical severity and outcome among COVID-19 infected patients in respect to viral load and immune and inflammatory response Coronavirus disease 19 infection Healthy volunteers accepted, Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) RUHS College of Medical Sciences India 2020-07-27 CTRI/2020/07/026755 Phase Not Applicable Not yet recruiting 1 200 Sonali Sharma 2020-07-31
Evaluation of Systemic and Oral Conditions of Pregnant Women and Their Babies, With Exposure to COVID-19 Infection Coronavirus disease 19 infection, Periodontal disease Healthy volunteers accepted, Female, Adolescents (13-17 yrs), Young Adults (18-44 yrs) University of Sao Paulo Bauru School of Dentistry, Faculdade de Odontologia de Bauru Brazil 2020-09-30 2022-12-31 FOBPREGNAT, NCT04492449 Phase Not Applicable Not yet recruiting 1 27 Months 260 2020-07-31
Hyponatremia in covid-19 patients Coronavirus disease 19 infection, Hyponatremia, Inflammatory disease Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Nacional Profesor Alejandro Posadas Argentina 2020-03-07 2020-07-21 HYPONATREMIA IN COVID PATIENTS, NCT04493268 Phase Not Applicable Completed 1 4 Months 250 CARLOS EGHI, physician, Ladislao Diaz Ballve, GRADUATE IN KINESIOLOGY 2020-07-31
An European phase II, multicenter, randomized, controlled, open-label clinical study to assess the efficacy and safety of asunercept in patients with severe COVID-19 disease Coronavirus disease 19 infection asunercept alone, standard of care alone CD95 antagonist Apogenix GmbH Russian Federation, Spain Phase 2 Clinical Not yet recruiting 2 400 2020-07-31
EXIT COVID-19: Extracellular Vesicle Infusion Therapy for Severe COVID-19 Coronavirus disease 19 infection, Hypoxia, Respiratory distress syndrome, Respiratory failure ExoFlo, Direct Biologics LLC alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Direct Biologics LLC US 2020-09-01 2020-12-31 DB-001, EXIT COVID-19, NCT04493242 Phase 2 Clinical Not yet recruiting 1 4 Months 60 Vikram Sengupta, Principal Investigator 2020-07-31
The epidemiological characteristic of real-time covid-19 cases in north-eastern peninsular Malaysia: Jan to July 2020 Coronavirus disease 19 infection Jabatan Kesihatan Negeri Kelantan 2020-07-30 NMRR-20-1624-55900 Phase not specified Status not specified 0 Dr HAZLIENOR BINTI MOHD HATTA 2020-07-31
Good-NIGHT COVID: Nasal washout and gargling for healthcare staff in Care Homes during the COVID-19 pandemic: The Good-NIGHT COVID pilot study Coronavirus disease 19 infection Gargling alone, Nasal lavage alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Of Southampton NIHR Applied Research Collaboration Wessex Malaysia ACTRN12620000737932, Good-NIGHT COVID, U1111-1252-7005 Phase not specified Not yet recruiting 1 250 Dr Thomas Daniels 2020-07-31
Evaluation of the effect of chronic use of Antimalarials on the frequency of infection with the New Corona Virus 2019 (Severe Acute Respiratory Syndrome Coronavirus 2 - SARS-CoV-2) in patients with Immunomedical Rheumatic Diseases Connective tissue disease, Coronavirus disease 19 infection, Inflammatory disease, Myopathy, Osteoarthritis, Rheumatoid arthritis, Scleroderma, Sjoegrens syndrome, Systemic lupus erythematosus Chloroquine alone, Hydroxychloroquine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Socidade Brasileira de Reumatologia Ministério da Saúde – Departamento de Ciência e Tecnologia (MS-DECIT) Brazil 30246120.3.1001.5505, RBR-9ktwx6 Phase Not Applicable Recruiting 1 9000 Cláudia diniz lopes marques, Marcelo Pinheiro 2020-07-31
Status of management of surgery in Beijing during COVID-1 Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Beijing Friendship Hospital, Capital Medical University ChiCTR2000033198 Phase Not Applicable Recruiting 0 500 Kai Pang, Zhongtao Zhang 2020-07-31
Intranasal Heparin Tolerability Study Coronavirus disease 19 infection heparin sodium alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Mississippi US 2020-08-31 2020-09-30 INTRANASAL HEPARIN, NCT04490239 Phase 0 Clinical Not yet recruiting 1 1 Month 6 Bill Gurley, PhD, Joshua S Sharp, PhD, Joshua Sharp 2020-07-30
Characteristics and Outcomes of Gastrointestinal Manifestations of COVID-19 Coronavirus disease 19 infection, Gastrointestinal disease Assiut University Egypt 2020-07-31 2020-09-30 COVID GASTRO INTESTINAL, NCT04490772 Phase Not Applicable Not yet recruiting 1 2 Months 200 Haidi Karam 2020-07-30
YCOVID: Rapid Diagnostic Test for COVID-19 Based on Antibody Detection Coronavirus disease 19 infection ELISA test alone, rapid diagnostic test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Corporacion Parc Tauli Spain 2020-06-22 2020-09-30 2020/587, NCT04490837, YCOVID Phase Not Applicable No longer recruiting 1 3 Months 3500 Juan Francisco Delgado de la Poza 2020-07-30
Comprehensive mental and physical health assessment and intervention studies for novel coronavirus pneumonia (COVID-19) patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Wuhan Jinyintan Hospital China ChiCTR2000035060 Phase Not Applicable Status not specified 1 2000 LIU YING, Wang Qiongya, Liu Zhengkui 2020-07-31
Inhalation of KELEA Excellerated Water in Covid-19 Infected Individuals Coronavirus disease 19 infection KELEA excellerated water intake alone Institute of Progressive Medicine US 2020-08-01 2020-11-30 KELEA-1, NCT04490824 Phase Not Applicable Recruiting 1 4 Months 100 W John Martin, MD, PhD 2020-07-31
An Observational Study of Integrated Chronic Pain Management in a Community Health Center Coronavirus disease 19 infection, Pain NextGen (NextGen EHR) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Washington University School of Medicine, US Logan University (US) US 2018-08-01 2020-05-25 NCT04490291, RD04240531 Phase Not Applicable Completed 1 21 Months 42 Chrisotpher Prater 2020-07-31
AmbcoviDD19: Assessment of disease progression, infection chains and seroprevalence of Covid-19 infections in Saxony Coronavirus disease 19 infection University Hospital Carl Gustav Carus Germany 2020-04-09 AmbcoviDD19, BO-EK-137042020, DRKS00022549 Phase Not Applicable Recruiting 1 250 Jakob Armann 2020-07-31
Efficacy and outcomes of Lian-Hua Qing-Wen capsule in the treatment of novel coronavirus pneumonia (COVID-19): a medical records based retrospective study Coronavirus disease 19 infection, Viral pneumonia Lian-Hua Qing-Wen capsule alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) 920th Hospital of the PLA Joint Logistics Support Force China ChiCTR2000035046 Phase Not Applicable Recruiting 1 147 Liu Zhiyong, Zhang Shurong 2020-07-31
A clinical trial of allogeneic bone marrow-derived mesenchymal stem cells for treatment of adult COVID-19 patients Coronavirus disease 19 infection allogeneic bone marrow-derived mesenchymal stem cells, Stemedica Cell Technologies alone Promedica Inc, Stemedica Cell Technologies Inc Phase 2 Clinical Status not specified 0 8 2020-07-30
A phase III clinical trial of COVID-19 vaccine for potential treatment of COVID-19 infection Coronavirus disease 19 infection SARS-CoV-2 vaccine (COVID-19), Sanofi Pasteur/GlaxoSmithKline alone COVID19 Spike glycoprotein modulator GlaxoSmithKline plc, Sanofi SA 2020-12-31 Phase 3 Clinical Planned 0 2020-07-30
A phase I/II clinical trial of COVID-19 vaccine for potential treatment of COVID-19 infection Coronavirus disease 19 infection SARS-CoV-2 vaccine (COVID-19), Sanofi Pasteur/GlaxoSmithKline alone COVID19 Spike glycoprotein modulator GlaxoSmithKline plc, Sanofi SA 2020-09-30 Phase 1/Phase 2 Clinical Planned 0 2020-07-30
FLARE: Favipiravir +/- Lopinavir: A RCT of Early antivirals Coronavirus disease 19 infection favipiravir alone, lopinavir + ritonavir alone, favipiravir plus lopinavir + ritonavir HIV protease inhibitor, RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University College London, University of London LifeArc UK 2020-07-16 2020-002106-68, CTU/2020/354, FLARE Phase 2 Clinical Recruiting 1 2020-07-31
Peruconplasma: Evaluating the use of convalescent plasma as management of COVID-19 Coronavirus disease 19 infection convalescent plasma alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidad Peruana Cayetano Heredia Peru 2020-06-01 PER-016-20, Peruconplasma Phase 2b Clinical Not yet recruiting 1 ALONSO RICARDO SOTO TARAZONA, Alonso Soto Tarazona, Enrique Argumanis Sánchez, Fiorella Krapp López, Martin Montes Delgado, Patricia García Funegra 2020-07-31
AP-PEDCOVID: Seroprevalence and Immunoprotection Against COVID-19 in Parisian Children Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Assistance Publique Hopitaux de Paris France 2020-04-09 2021-12-31 AP-PEDCOVID, HNECKERNM, NCT04490811 Phase Not Applicable Recruiting 2 20 Months 800 Isabelle Sermet-Gaudelus, Professor, Philippe Tourenne, SERMET Isabelle, Professor 2020-07-31
Convalescent plasma as treatment for COVID-19 Coronavirus disease 19 infection convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) SEGURO SOCIAL DE SALUD- ESSALUD Peru 2020-06-01 ESSALUD-012020, PER-013-20 Phase 2 Clinical Not yet recruiting 1 192 ARTURO SAGASTEGUI SOTO, AUSBERTO CHUNGA CHUNGA, CHIRISTIAN Villanueva GONZALES, IBETH MELANIA NEYRA VERA, JORGE MAGUIÑA QUISPE, LEDA YAMILEE HURTADO ROCA, PERCY SOTO BECERRA, ROGER VLADIMIR ARAUJO CASTILLO 2020-07-31
What Are the Clinical Factors Associated With a Significant Pain Reduction Following Physiotherapy in Patients With Temporomandibular Disorders Coronavirus disease 19 infection, Temporomandibular joint syndrome Physiotherapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Italian Institute Stomatologico The University of Birmingham Italy 2019-06-14 2020-12-31 NCT03990662, PREDICTORSOUTCOMETMD2019GA Phase Not Applicable Recruiting 1 18 Months 100 Giacomo Asquini 2020-07-30
The Fenland COVID Study: A study to understand the progression and early signs of COVID-19 infection Coronavirus disease 19 infection smartphone app alone Huma University of Cambridge 2020-07-23 The Fenland COVID Study Phase Not Applicable Recruiting 0 2020-07-30
A clinical trial of anti-SARS-CoV-2 spike protein mAb (COVID-19), Adagio Therapeutics for the potential treatment and prevention of SARS-CoV-2 infection (COVID-19) Coronavirus disease 19 infection anti-SARS-CoV-2 spike protein mAb (COVID-19), Adagio Therapeutics alone COVID19 Spike glycoprotein modulator Adagio Therapeutics 2020-12-31 Phase Not Applicable Planned 0 2020-07-30
A randomized, double-blind, placebo-controlled, pilot study to evaluate the feasibility of RTB-101 compared to placebo for COVID-19 post-exposure prophylaxis in older adults Coronavirus disease 19 infection dactolisib alone Phosphoinositide 3-kinase inhibitor, mTOR complex 1 inhibitor, mTOR complex 2 inhibitor Aged Adults (65-79 yrs), Elderly Adults (80 and over) resTORbio Inc Harvard Medical School, National Institute on Aging, University of Connecticut Health Center Phase Not Applicable Planned 0 60 2020-07-30
Serological Surveillance for COVID-19 in Central North Carolina Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute Of Environmental Health Sciences National Institutes of Health Clinical Center US 2020-08-03 2022-06-01 20-E-0143, 200143, NCT04490174 Phase Not Applicable Recruiting 1 21 Months 2500 Nicole Edwards, Stavros Garantziotis, M.D. 2020-07-30
Post-ICU Follow-up in Patients With Severe SARS-CoV-2 Infection (COVID-19) Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Université De Strasbourg 2020-07-27 2021-07-27 7890, NCT04491214 Phase Not Applicable Not yet recruiting 0 12 Months 131 Walid OULEHRI 2020-07-30
SCEI: Stress Induced by the COVID-19 Pandemic and Non-confinement: Study of Anxiety Factors and Potential Effects on Immunity Anxiety disorder, Coronavirus disease 19 infection, Post traumatic stress disorder COVID-19 questionnaire alone, Experiences in Close Relationship Scale questionnaire (ECR-S) alone, Generalized Anxiety Disorder-7 (GAD 7) alone, Patient Health Questionnaire (PHQ-9) alone, Post Traumatic Stress Disorder questionnaire (PTSD-8) alone, mental health questionnaire alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire de Saint Etienne UK, France 2020-07-31 2020-12-31 20CH129, NCT04491071, SCEI Phase Not Applicable Not yet recruiting 2 5 Months 405 Claude LAMBERT, MD PhD HDR, Fleur PETIT, CRA 2020-07-30
BARCONA: An investigator-sponsored, phase II trial to evaluate the effect of bardoxolone in patients suffering from COVID-19 Coronavirus disease 19 infection bardoxolone methyl (oral, pulmonary arterial hypertension/ diabetic nephropathy), Reata/ Kyowa Hakko Kirin alone I-kappa B kinase inhibitor, Kelch like ECH associated protein 1 modulator, NFE2L2 gene stimulator, Nuclear factor kappa B inhibitor, STAT3 gene inhibitor Reata Pharmaceuticals Inc US 2020-07-28 BARCONA Phase 2 Clinical Recruiting 1 Sripal Bangalore 2020-07-30
HemoCov: COVID-19 Quarantine on Musculoskeletal Status in Hemophilia Bleeding, Coronavirus disease 19 infection, Factor IX deficiency, Factor VIII deficiency, Joint disease, Pain Healthy volunteers accepted, Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidad Europea De Madrid Spain 2020-07-01 2020-07-29 HEMOCOV, HemoCov, NCT04491318 Phase Not Applicable Recruiting 1 27 Rubén Cuesta-Barriuso, PhD 2020-07-31
A single-center, cohort observational study to evaluate clinical characteristics and short-term outcome of kidney transplant patients admitted for SARS-CoV2 pneumonia Coronavirus disease 19 infection, Pneumonia anti-viral therapy alone, hydroxychloroquine alone, methylprednisolone alone, tocilizumab alone Azienda Ospedaliera Spedali Civili di Brescia, Universita degli Studi di Brescia Phase Not Applicable Status not specified 0 20 2020-07-30
VESTA: Effectiveness of a Novel Respirator With Chitosan Nanoparticles Coronavirus disease 19 infection VESTA respirator alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) University of Brasilia Centro de Pesquisa em Biotecnologia Ltda, Hospital Regional da Asa Norte, Hospital da Região Leste, Universidade Estadual de Campina, University Hospital of Brasilia Brazil 2020-08-30 2021-07-31 32862320.0.0000.0030, NCT04490200, VESTA, VESTA TRIAL Phase Not Applicable Not yet recruiting 1 11 Months 1000 Aline M Toledo, PhD, Glécia V Silva Luz, PhD, Graziella A Joanitti, PhD, Henry M Peixoto, PhD, Marcella L Brettas Carneiro, PhD, Mario Fleury Rosa, PhD, Rodrigo L Carregaro, PhD, Suelia S Fleury Rosa, PhD 2020-07-30
Umbilical Cord Tissue (UC) Derived Mesenchymal Stem Cells (MSCs) Versus Placebo to Treat Acute Pulmonary Inflammation Due to COVID-19 Coronavirus disease 19 infection, Hypoxia, Lung inflammation, Respiratory distress syndrome umbilical cord-derived mesenchymal stem cells (intravenous, COVID-19/lung inflammation/acute lung injury/acute respiratory distress syndrome), University of Miami alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) KCNQ2 Cure Alliance Foundation, University of Miami, University of Miami Miller School of Medicine US 2020-08-01 2024-06-01 20200575, NCT04490486 Phase 1 Clinical Not yet recruiting 3 46 Months 21 Camillo Ricordi, M.D, Joshua M Hare, MD, Yvenie Desire, BS 2020-07-31
Simulation study of tracheal intubation through an aerosol-box assuming COVID-19 Coronavirus disease 19 infection AirWay Scope S-100 (Pentax) alone, Laerdal Airway Management Trainer (Laerdal Medical Japan Ltd) alone, Macintosh laryngoscope (Riester) alone, McGRATH MAC (Aircraft Medical Ltd) alone, SealGuard Evac cuffed tracheal tube (Covidien) alone, Shiley Intubation Stylet (Covidien) alone, Splash Guard CG:SGCG aerosol box alone, mask ventilation alone, tracheal intubation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tokyo Women's Medical College Japan 2020-05-01 UMIN000040289 Phase Not Applicable No longer recruiting 1 30 Idei Masafumi, Masafumi Idei 2020-07-31
On-line Neuromuscular Exercise and Education for Knee Osteoarthritis Coronavirus disease 19 infection, Osteoarthritis GLA:D exercise and education program alone, on-line NEMEX-TJR neuromuscular exercise alone, on-line education alone, on-line stretching exercise alone, on-line warm-up exercise alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Slagelse Hospital Region Zealand Denmark 2020-06-12 2021-12-31 J.NR. 20-000013, NCT04437134, SLAGELSEH Phase Not Applicable Recruiting 4 18 Months 500 Pætur M Holm, PhD, Søren T Skou, Professor 2020-07-30
ALADDIN: Quality of Life and Addiction Among Hospital Night Workers Coronavirus disease 19 infection, Drug dependence, Post traumatic stress disorder, Psychiatric disorder Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Universite Denis Diderot Assistance Publique Hopitaux de Paris, INSERM France 2020-06-15 2023-06-01 ALADDIN, ALADDIN-QOLHOSPWORK, NCT04291534 Phase Not Applicable Not yet recruiting 1 35 Months 1800 Dr Martin Duracinsky 2020-07-30
Esophagogastroduodenoscopy (EGD) is an Aerosol-generating Procedure: Proof of Concept Study Coronavirus disease 19 infection, Gastrointestinal disease esophagogastroduodenoscopy alone Chinese University of Hong Kong Hong Kong 2020-05-07 2021-01-31 2020.200, NCT04400734 Phase Not Applicable Recruiting 1 8 Months 60 Chan Shannon Melissa, Philip Chiu, FRCSEd, Shannon Chan, FRCSEd 2020-07-30
A trial to evaluate ADEXUSDx COVID-19 Antibody Test to measure the presence of SARS-CoV-2 antibodies for the diagnosis of COVID-19 Coronavirus disease 19 infection ADEXUSDx COVID-19 Antibody Test alone NOWDiagnostics Inc Phase Not Applicable Planned 0 2020-07-30
CMDA-SURVEY2: National Survey of the Impact of COVID-19 Pandemics Coronavirus disease 19 infection customized questionnaire alone, social software WeChat alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry Peking Union Medical College Hospital China 2020-07-27 2020-09-27 CMDA-SURVEY2, CMDA-SURVEY2, NCT04491201 Phase Not Applicable Recruiting 1 2 Months 6000 Lei Li, M.D., Lei Li, MD 2020-07-30
Assessment of the Psychosocial Impact of the COVID-19 Pandemic on the MD Anderson Cancer Center Workforce Coronavirus disease 19 infection online questionnaire alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) MD Anderson Cancer Center National Cancer Institute US 2020-05-18 2021-04-30 2020-0428, NCI-2020-04259, NCT04491292 Phase Not Applicable Recruiting 1 11 Months 20000 Priya R Bhosale, Priya R. Bhosale 2020-07-30
A Qualitative study regarding stress and coping in Front-line Health Care Doctors at a tertiary-care hospital Acute stress disorder, Coronavirus disease 19 infection, Psychiatric disorder depth interview alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) B. J. Medical College, Pune India 2020-08-17 CTRI/2020/07/026788 Phase Not Applicable Not yet recruiting 0 20 Dr Ivan Stanley Netto 2020-07-31
Global Assessment of Acute and Chronic Kidney Disease Incidence and Outcomes in Patients With COVID-19 Infection Coronavirus disease 19 infection, End stage renal disease, Renal disease, Renal injury Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of California San Diego US, Canada, Chile, UK, India, Bolivia 2020-05-05 2023-03-31 000295, NCT04491227 Phase Not Applicable Recruiting 12 34 Months 2000 Ravindra L Mehta 2020-07-30
INHALE: Inhale work package 3 - rapid versus standard testing to diagnose lung infections in intensive care, including COVID-19 observational sub-study Coronavirus disease 19 infection, Lower respiratory tract infection, Viral pneumonia BioFire FilmArray alone, standard care alone University College London NIHR Central Commissioning Facility UK 2018-10-01 2021-06-30 41211, INHALE, ISRCTN16483855 Phase Not Applicable Recruiting 12 33 Months 466 Dr Enne 2020-07-30
postcorona: Postcorona care Coronavirus disease 19 infection, Heart disease, Inflammatory disease, Lung disease, Psychotic disorder, Pulmonary fibrosis Leiden University Medical Center Netherlands 2020-07-13 2020-12-22 NL8775, postcorona Phase Not Applicable Recruiting 1 5 Months 90 Geert Groeneveld 2020-07-31
A clinical trial to study the effects of an Ayurvedic medicine, Haldi 30 (Turmeric extract) drops in patients with Corona virus infection Coronavirus disease 19 infection Haldi 30 alone, Standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sahyadri Hospitals India 2020-08-03 CTRI/2020/07/026841 Phase 2 Clinical Not yet recruiting 2 260 Dr Sarang Phadke 2020-07-30
Determination of dandelion capsule on patient with COVID-19 virus Coronavirus disease 19 infection Variable regimens including Dandelherb (Booali Daro Pharmaceutical Factory) , dexamethasone , interferon beta-1b , remdesivir COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ghoum University of Medical Sciences Iran 2020-07-26 IR.MUQ.REC.1399.148, IRCT20180513039641N2 Phase 3 Clinical Recruiting 1 80 Ehsan Sharifipour, Hoda Abolhasani, Reihaneh Tabaraie, hoda Abolhasani 2020-07-30
Evaluating the effects of intravenous immunoglobulin (IVIG) in COVID-19 patients Coronavirus disease 19 infection Variable regimens including IVIG (Biotest) , hydroxychloroquine (Tehran Daroo) , lopinavir + ritonavir (Hetero Labs Limited) Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Shaheed Beheshti Medical University Iran 2020-07-09 IR.SBMU.NRITLD.REC.1399.143, IRCT20151227025726N20 Phase 2/Phase 3 Clinical Recruiting 1 80 Afshin Zarghi, Farzaneh Dastan, Payam Tabarsi, Zahra Mirshafiei Langari 2020-07-30
Safety and Efficacy of EDP-1815 in the Treatment of Patients Hospitalized With COVID-19 Infection Coronavirus disease 19 infection EDP-1815 alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Evelo Biosciences Inc, Robert Wood Johnson University Hospital, Rutgers University US 2020-08-07 2020-12-21 EDP1815-205, NCT04488575 Phase 2 Clinical Not yet recruiting 4 4 Months 60 Daniela Walker, Deborah McCloskey, Douglas Maslin, MD, Keith Guevarra, MD, Randall Teeter, Reynold A. Panettieri, Jr., M.D 2020-07-31
PERSO-COVID: Medical and Serological Follow-up of the Staff of the Paris Saint-Joseph Hospital Group Infected With Severe Acute Respiratory Syndrome Coronavirus 2. Coronavirus disease 19 infection Serology test follow-up alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Groupe Hospitalier Paris Saint-Joseph France 2020-07-01 2021-12-31 NCT04488484, PERSO-COVID, PERSO-COVID Phase Not Applicable No longer recruiting 1 18 Months 450 2020-07-31
STAND UP to SARS-CoV-2 (COVID-19): Using Behavioural Economics to Reduce Sedentary Behaviour in At-home Office Workers Coronavirus disease 19 infection Long-List Choice Group alone, No Choice Group alone, Short List Choice Group alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Western Ontario Duke University Canada 2020-09-30 2020-12-31 116127, NCT04488796 Phase Not Applicable Not yet recruiting 1 3 Months 135 Kirsten Dillon, MA, Marc Mitchell, PhD, Marc Mittchell, PhD 2020-07-31
COVAP: Pathogens Involved in Secondary Infections During Severe Forms of Covid-19 Pneumonia Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Groupe Hospitalier Paris Saint-Joseph Centre Hospitalier Victor Dupouy France 2020-05-06 2020-11-30 COVAP, COVAP, NCT04488510 Phase Not Applicable No longer recruiting 1 6 Months 150 2020-07-30
DECOR-19: Delayed Colorectal Cancer Care During Coronavirus Disease (COVID-19) Pandemic Colorectal tumor, Coronavirus disease 19 infection Treviso Regional Hospital Universita degli Studi di Roma La Sapienza, Universita' Degli Studi "Magna Graecia" Di Catanzaro Italy 2020-05-20 2020-06-10 DECOR-19, NCT04488549, TREVISO Phase Not Applicable Completed 1 1051 Gaetano Gallo, Gian Luca Di Tanna 2020-07-30
Can Remote Photoplethysmography Be Used for Contactless Vital Sign Acquisition in a Healthcare Setting? A Prospective, Comparative Study Coronavirus disease 19 infection Masimo Radical 7 alone, Welch Allyn Connex Vital Signs Monitor alone, Welch Allyn Vital Signs Monitor alone, remote photoplethysmography (rPPG) vital sign acquisition alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Lady Davis Institute Carebook Technologies Inc Canada 2020-08-01 2020-11-30 2021-2376, NCT04489407 Phase Not Applicable Not yet recruiting 1 4 Months 350 Noura Hassan, Noura Hassan, MD, MPH 2020-07-29
Study of skin, hair and nail changes after COVID 19 illness Coronavirus disease 19 infection, Dermatological disease Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gujarat Cancer Society Medical college hospital and research centre India 2020-08-24 CTRI/2020/07/026821 Phase Not Applicable Not yet recruiting 1 500 Dr Nayan H Patel 2020-07-30
BET: A NIAID-sponsored Big Effect trial (BET) to assess the combination of lenzilumab and remdesivir on treatment outcomes versus placebo and remdesivir in hospitalized COVID-19 patients Coronavirus disease 19 infection lenzilumab plus remdesivir COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, GM-CSF ligand inhibitor, Immunoglobulin G1 modulator, Immunoglobulin kappa modulator, RNA polymerase modulator Humanigen Inc, National Institute of Allergy and Infectious Diseases BET Phase Not Applicable Status not specified 0 2020-07-29
Curcumin for COVID-19 Pre Exposure Prophylaxis Coronavirus disease 19 infection curcumin alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute Of Medical Sciences, Rishikesh India 2020-08-09 CTRI/2020/07/026820 Phase 4 Clinical Not yet recruiting 1 200 Rohit Walia 2020-07-30
Comparison of two different types of simple non-invasive oxygen therapy devices in coronavirus lung infection Coronavirus disease 19 infection, Lung infection, Respiratory failure, Viral pneumonia High Flow Nasal Oxygen alone, Optiflow alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Medical Sciences India 2020-07-27 CTRI/2020/07/026835 Phase 3 Clinical Not yet recruiting 1 100 Dalim Kumar Baidya 2020-07-30
A clinical trial of anti-coronavirus vaccine,State Research Center of Virology and Biotechnology VECTOR for the treatment of COVID-19 Coronavirus disease 19 infection anti-coronavirus vaccine,State Research Center of Virology and Biotechnology VECTOR alone State Research Center of Virology and Biotechnology VECTOR Phase Not Applicable Not yet recruiting 0 2020-07-29
Survival and 30-days Hospital Outcome in COVID-19 Patients in Upper Egypt Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Assiut University Egypt 2020-03-15 2020-07-01 ASSIUTU17, NCT04488588 Phase Not Applicable Completed 2 3 Months 1064 Aliae Mohamed-Hussein, MD 2020-07-30
Open Skies: Use of new technology for rapid detection of SARS-CoV2 Coronavirus disease 19 infection NAOR platform alone, Terasystem Breath Analyser test alone, VIRION test alone, Voice Pattern test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry Defence Research & Development Organisation Defence Institute of Physiology and Allied Sciences (DIPAS) India 2020-08-05 CTRI/2020/07/026843, Open Skies, Open Skies Phase Not Applicable Recruiting 4 10000 Dr Ambuj Garg, Dr Anil Gurtoo, Dr Desh Deepak, Dr Naresh Kumar, Dr Reena Mariya 2020-07-31
Nimesulide in COVID-19 infection Coronavirus disease 19 infection, Viral pneumonia Variable regimens including azithromycin , enoxaparin sodium , nimesulide , sucralfate Cyclooxygenase 2 inhibitor, Low molecular weight heparin Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shaheed Zulfiqar Ali Bhutto Medical University Islamabad Iran 2020-07-28 IRCT20200723048178N1, No.F.1-1//2015/ERB/SZABMU/605 Phase 2 Clinical Recruiting 1 60 Ahmed Farhan 2020-07-30
REaCHing to you with listening ears: A friendly telephonic interaction program for the DDU-GKY members Coronavirus disease 19 infection Assertive linkage with community resources alone, Proactive Engagement and Crisis Intervention alone, Problem-solving oriented supportive therapy alone Healthy volunteers accepted, Young Adults (18-44 yrs) Rajagiri college of Social Sciences UK India Education Research Initiative (UKIERI) India 2020-08-07 CTRI/2020/07/026834 Phase Not Applicable Not yet recruiting 26 1480 Dr Saju M D 2020-07-30
Artificial intelligence and machine learning for Covid 19 Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Visvesvaraya Technological University (VTU) India 2020-07-13 CTRI/2020/07/026832 Phase 1 Clinical Not yet recruiting 1 100 Dr DwajaniS, Dr Mukesh PR 2020-07-30
Sildenafil in COVID-19 Coronavirus disease 19 infection, Ischemia sildenafil alone PDE 5 inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidad Andres Bello Hospital Naval Almirante Nef Chile 2020-08-31 2021-03-31 NCT04489446, UNAB-003 Phase 1/Phase 2 Clinical Not yet recruiting 1 7 Months 40 Cesar Reyes, MD, Dominique Boisier, MD, Eduardo Labarca, MD, Felipe M Martinez, MD, MSc, Felipe Martinez, MD, MSc, Jaime Vidal, MD, Jorge Vega, MD, Mario Santamarina, MD, Miguel Gutierrez, MD, Monica Gutierrez, MD, Nicole Retamal, Roberto Contreras, MD, Sebastian Ahumada, MD 2020-07-31
COVID-19: Attitude Toward Quarantine Coronavirus disease 19 infection Taibah University Saudi Arabia 2020-07-15 2020-08-15 55834, NMRR-20-1574-55834 Phase Not Applicable Status not specified 1 1 Month Noordin othman, Suhana Jawahir 2020-07-30
Hydroxychloroquine for COVID-19 Coronavirus disease 19 infection hydroxychloroquine alone National Institutes of Health Malaysia Malaysia 2020-08-03 2020-09-03 54669, NMRR-20-1593-54669 Phase Not Applicable Status not specified 1 1 Month dr Nor Asiah Muhamad 2020-07-30
A study to assess the effectiveness of Ayurvedic formulation Guduchi Ghan vati in Covid-19 cases Coronavirus disease 19 infection Guduchi Ghan Vati alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ministry of Ayush India 2020-07-28 CTRI/2020/07/026840 Phase 2 Clinical Recruiting 1 30 Dr Nitin Ujjaliya, Dr Vivek Khare, Prof Umesh Shukla 2020-07-30
Facts on Bear Bile Use in Coronavirus Disease 2019 (COVID-19) Coronavirus disease 19 infection Bear Bile alone Institute For Medical Research (Inc In Malaysia) Malaysia 2020-04-01 2020-06-01 55957, NMRR-20-1604-55957 Phase Not Applicable Status not specified 1 2 Months Ms. Lim Xin Yi, Terence Tan Yew Chin 2020-07-31
LUS: lung ultrasound Coronavirus disease 19 infection ultrasound alone Hospital Sungai Buloh Malaysia 2020-07-27 2020-12-31 55711, NMRR-20-1599-55711 Phase Not Applicable Status not specified 1 5 Months Dr ELISA AUDREY EDDIE, Dr Mahathar Abdul Wahab 2020-07-30
Antibody, RT-PCR, COVID-19 Coronavirus disease 19 infection RT-PCR alone Hospital Sungai Buloh Malaysia 2020-07-31 2021-07-30 55832, NMRR-20-1598-55832 Phase Not Applicable Not yet recruiting 1 12 Months DR THARMINI A/P RAVI, Dr Suresh Kumar 2020-07-31
A phase II/III clinical trial of CodaVax-COVID for the prevention of Covid-19 Coronavirus disease 19 infection CodaVax-COVID alone Codagenix Inc, Serum Institute of India Ltd hVIVO plc Phase 2/Phase 3 Clinical Planned 0 2020-07-29
A trial to evaluate rigosertib for the treatment of patients with COVID-19 disease Coronavirus disease 19 infection rigosertib sodium (iv, MDS/solid tumors), Onconova/SymBio alone AKT protein kinase inhibitor, BCL2L11 gene stimulator, Cyclin D1 inhibitor, Cyclin-dependent kinase-1 inhibitor, Jun N terminal kinase modulator, MAP kinase inhibitor, Phosphoinositide 3-kinase inhibitor, Polo-like kinase 1 inhibitor, Raf protein kinase inhibitor Onconova Therapeutics Inc Phase Not Applicable Planned 0 2020-07-29
HOMECOMIN': Home Monitoring and Evaluation After Admission for COVID-19 in the Netherlands Coronavirus disease 19 infection, Pulmonary fibrosis spirometer (Spirobank Smart) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Erasmus University Medical Center Rotterdam Dutch Society of Physicians for Pulmonology and Tuberculosis, Leiden University Medical Center, VU University Medical Center Netherlands 2020-05-08 2021-12-31 HOMECOMIN', MEC-2020-0318, NCT04488562 Phase Not Applicable Recruiting 3 19 Months 150 C.C. Moor, drs, Cintha Klop, E.J. Nossent, Esther van der Kaay, G Nakshbandi, G. Nakshbandi, drs, Gizal Nakshbandi, drs, J.J.M. Geelhoed, dr, M.S. Wijsenbeek, dr 2020-07-30
Impact of Isolation in Patients With IBD During the COVID-19 Crisis Coronavirus disease 19 infection, Inflammatory bowel disease Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sheffield Teaching Hospitals NHS Foundation Trust UK 2020-06-30 2022-06-30 NCT04488471, STH21414 Phase Not Applicable Recruiting 1 24 Months 232 Alan Lobo, MD, Luke Barron, MSc 2020-07-30
Clinical trial of Annual SZ drug in Covid-19 Coronavirus disease 19 infection Anval SZ plus azithromycin Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Shaheed Beheshti Medical University Iran 2020-06-09 IR.SBMU.RETECH.REC.1399.158, IRCT20200607047682N1 Phase 2/Phase 3 Clinical No longer recruiting 1 60 Afshin Zarghi, Hamid Chegini, Mohammad Farhbakhsh, Zuhair Sarraf 2020-07-30
Evaluation of the efficacy and safety of inhaled magnesium sulfate in combination with standard treatment in Covid-19 patients Coronavirus disease 19 infection magnesium sulfate alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shaheed Beheshti Medical University Iran 2020-07-27 IR.SBMU.NRITLD.REC.1399.148, IRCT20191211045691N1 Phase 3 Clinical Recruiting 1 100 Guitti Pourdowlat, Seyed Ruhollah Mousavinasab, ‪Parissa Farnia 2020-07-30
Tele-health Enabled Clinical Trial for COVID19 Coronavirus disease 19 infection, Immune disorder Doctella device alone, cholecalciferol alone, telehealth monitoring alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospitals of Cleveland Northwestern University US 2020-08-01 2021-08-01 NCT04489628, STUDY20200461 Phase 1/Phase 2 Clinical Not yet recruiting 1 12 Months 110 Amanda Davies, Kevin Cooper, MD, Kurt Lu, MD, Lyndsey O'Hara, BSN, Wesley Yu, MD 2020-07-30
CoronaKids: CoronaKids - Epidemiological data acquisition SARS-CoV2/Covid-19 Coronavirus disease 19 infection epidemiological data analysis alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Univ Witten / Herdecke Germany 2020-03-27 61/2020, CoronaKids, DRKS00021229 Phase Not Applicable Recruiting 1 900 Stefan Wirth 2020-07-30
CCHROMO: COVID19 Chronic Morbidity: Follow-up of patients with COVID19 and non-COVID19 pneumonia with respect to clinical status, pulmonary function and radiologic findings Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitätsklinikum Frankfurt Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie Hannover Medical School Germany 2020-07-27 20-748, CCHROMO, DRKS00022475 Phase not specified Not yet recruiting 1 500 Gernot Rohde 2020-07-30
CovPall: Improving palliative care for people affected by the COVID-19 pandemic by sharing learning - the national and international response Coronavirus disease 19 infection palliative care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) King's College London Cicely Saunders International, Kings College Hospital NHS Trust, National Institute for Health Research (NIHR) Switzerland, Argentina, South Africa, Portugal, UK, Canada, Ireland, Netherlands, India, Brazil, Australia 2020-04-01 2021-04-24 CovPall, ISRCTN16561225, LRS-19/20-18541, IRAS 282824 Phase Not Applicable Recruiting 13 12 Months Miss Cripps 2020-07-30
Study of Shreepad Shree Vallabh SSV Formulation in management of COVID-19 Coronavirus disease 19 infection SSV Formulation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) SSV Phytopharmaceuticals India 2020-08-05 CTRI/2020/07/026839, SSV-SF-07/2020 Phase 3 Clinical Not yet recruiting 1 150 Dr Sagar Mandlik, Dr Yogesh Dound 2020-07-30
PREDISCAN: Predicting the Progression to Chronic Fibrosis of Lung Lesions Related to Covid-19 Infection From Chest CT Images Coronavirus disease 19 infection, Pulmonary fibrosis, Viral pneumonia Chest CT scan alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Association Marie Lannelongue France 2020-06-08 2021-11-08 2020-A01322-37, NCT04483752, PREDISCAN Phase Not Applicable Recruiting 3 17 Months 100 CAROLINE CARAMELLA, MD, Corinne Institut Gustave Roussy (IGR), MD, Marie De Torcy 2020-07-30
Antibody response to COVID-19 in health care workers Coronavirus disease 19 infection LIAISON SARS-CoV-2 S1/S2 IgG test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) DiaSorin Healthcare India Private Limited, Ortho Clinical Diagnostics India Private Limited India 2020-08-04 Phase Not Applicable Not yet recruiting 1 Dr Smita Sarma 2020-07-29
Effect of COVID - 19 pandemic researchers Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Manipal Academy of Higher Education India 2020-08-10 CTRI/2020/07/026836 Phase Not Applicable Not yet recruiting 1 1850 Elsa Sanatombi Devi 2020-07-30
Encouraging behavior to reduce the spread of COVID-19 Coronavirus disease 19 infection Impact Others, Cooperative Linear Production (IOCLP) message alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Yale University US 2020-05-01 2020-07-24 1312013102, ISRCTN17896927 Phase Not Applicable Completed 2 2 Months 3000 Prof Huber 2020-07-30
N-terminal Pro B-type Natriuretic Peptide and Vitamin D Levels as Prognostic Markers in COVID-19 Pneumonia Coronavirus disease 19 infection, Hypoxia, Respiratory failure, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cairo University Kasr El Aini Hospital Egypt 2020-07-01 2021-01-01 2020-7-1, NCT04487951 Phase Not Applicable Recruiting 1 6 Months 100 Akram Abdelbary, Prof., Noha A. Radwan, Noha A. Radwan, Lecturer, Noha A. Radwan, Lecturer of Chemical pathology, Noha Radwan, Lecturer, Yasmine Elshiwy, Ass. Prof. 2020-07-30
Complementary Intervention for COVID-19 Coronavirus disease 19 infection conventional therapy alone, Boswellia Serrata gum plus Licorice extract Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Assiut University Egypt 2020-01-01 2021-01-31 0925-0586, NCT04487964 Phase Not Applicable Recruiting 1 13 Months 70 Adel A. Gomaa, Ph.D., Adel Gomaa, Ph.D., Hamdy S Mohamed, MD, Mostafa Hamdy, Ph.D. 2020-07-30
SARS-CoV2 (COVID-19) Seroepidemiological Transplanted Subjects (Kidney, Kidney-pancreas, Pancreas, Langerhans Islets) Coronavirus disease 19 infection, Kidney transplantation, Pancreas transplantation Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) IRCCS San Raffaele Italy 2020-07-15 2021-01-15 COVID-SIERO TRAPIANTI, NCT04487197 Phase Not Applicable Recruiting 1 6 Months 300 Antonio Secchi, MD, Federica Pazzi, Paola Maffi, Rossana Caldara 2020-07-30
A Phase I, Prospective, Open-labeled Study to Evaluate the Safety and Immunogenicity of MVC-COV1901 Coronavirus disease 19 infection MVC-COV1901 alone COVID19 Spike glycoprotein modulator, TLR-9 agonist Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Medigen Vaccine Biologics Corp Taiwan 2020-09-01 2021-12-31 CT-COV-11, NCT04487210 Phase 1 Clinical Not yet recruiting 1 16 Months 45 Criss Cheng, Szu-Min Hsieh, MD 2020-07-30
Respiratory Mechanics and Gas Exchange Characteristics in Patient With SARS-CoV-2 Coronavirus disease 19 infection, Respiratory distress syndrome positive end-expiratory pressure therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sanatorio Anchorena San Martin Argentina 2020-07-01 2020-10-20 10.2020, NCT04486729 Phase Not Applicable Recruiting 1 3 Months 15 Javier H Dorado, PT, Joaquin Pérez, PT, Matias Accoce 2020-07-30
Exploring the Impact of a Sleep App on Sleep Quality Coronavirus disease 19 infection, Insomnia sleep app (Pro version) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University College London University of California Los Angeles UK 2020-02-13 2020-08-15 NCT04487483, SLEEPAPPEVALUATION Phase Not Applicable No longer recruiting 1 6 Months 101 Abi Fisher 2020-07-29
DAMPEN-CI: Duvelisib Ameliorates Manifestations of Pneumonia in Established Novel Coronavirus Infection (COVID-19) Coronavirus disease 19 infection, Inflammatory disease, Viral pneumonia duvelisib alone Phosphoinositide-3 kinase delta inhibitor, Phosphoinositide-3 kinase gamma inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Emory University University of Pennsylvania, Verastem Oncology US 2020-08-31 2022-02-28 DAMPEN-CI, NCT04487886, STUDY00000701 Phase 2 Clinical Not yet recruiting 3 18 Months 80 Aneesh Mehta, MD, Edmund Waller, MD, PhD 2020-07-29
Hematology and Clinical Picture in Pediatric COVID-19 Infection Coronavirus disease 19 infection, Hematological disease Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Benha University Egypt 2020-07-26 2020-08-21 NCT04487119, RC 6-7-2020 Phase Not Applicable Not yet recruiting 1 30 Effat H Assar, MD, Rana A Khashaba, MD, Shaimaa R Abdelmaksoud, MD 2020-07-29
PLEXIT: Therapeutic Plasma Exchange (TPE) for COVID-19 Cytokine Release Storm (CRS) Coronavirus disease 19 infection, Hypoxia, Respiratory distress syndrome, Respiratory failure, Sepsis, Viral pneumonia COBE Spectra Apheresis machine version 7 (TERUMO BCT) alone, anticoagulation therapy alone, corticosteroids therapy alone, ulcer prophylaxis alone, Variable regimens including Fresh frozen Plasma (FFP) , aspirin , methylprednisolone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) United Nations International Children's Fund Pak Emirates Military Hospital Pakistan 2020-04-01 2020-06-30 NCT04485169, PLEXIT, SULTAN MEHMOOD KAMRAN Phase 2 Clinical Completed 1 3 Months 280 Imran m Fazal, FCPS, Sultan mehmood kamran 2020-07-29
A pan-India phase IV trial of itolizumab in COVID-19 patients Coronavirus disease 19 infection itolizumab alone T-cell differentiation antigen CD6 inhibitor Biocon Ltd Phase 4 Clinical Planned 0 200 2020-07-30
FERTICOVID: Presence of SARS-CoV-2 in Semen: Impact on Fertility Preservation in Male Oncological Patients? Cancer, Coronavirus disease 19 infection RT- qPCR alone, nasopharyngeal swab test alone, serological test alone Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Clermont-Ferrand Biomedicine Agency France 2020-07-10 2021-07-31 2020-A01409-30, FERTICOVID, NCT04487639, RNI 2020 BRUGNON Phase Not Applicable Recruiting 16 12 Months 250 Amélie BREBION, PharmD, Anne MAYEUR, MD, PhD, Anne-Sophie CANEPA, MD, Arthur LUTON, MD, Audrey MIRAND, PharmD, PhD, Aurélie RIVES-FERAILLE, MD, Badria BENNANI SMIRES, MD, Béatrice DELEPINE, MD, Carole Carole, MD, Caroline AIMONE VIANNA, MD, Catherine DILIGENT, MD, PhD, Catherine GUILLEMAIN, MD, Catherine PATRAT, MD, Charlotte DUPONT, MD, PhD, Charlotte MAUROY, MD, Cécile GREZE, MD, Cécile HENQUELL, PharmD, PhD, Céline BOUILLON, MD, Céline BRUNO, MD, Céline CHALAS, MD, Diane RIVET-DANON, MD, Elsa LABRUNE, MD, Emmanuel DULIOUST, MD, PhD, Fanny JUMEAU, MD, Florence BOITRELLE, MD, PhD, Florence BRUGNON, MD, PhD, Florence EUSTACHE, MD, Hanae Pons-Rejraji, PhD, Isabelle KOSCINSKI, MD, PhD, Isabelle LICHTBLAU, MD, Jacqueline LORNAGE, MD, PhD, Jacqueline SAIAS-MAGNAN, MD, Jessika MOREAU, MD, Julie BARBERET, MD, Julien BESSONAT, MD, Laetitia LADUREAU-FRITSCH, MD, Laure CHAPUT, PD, Laëtitia HESTERS, PharmD, Lise LACLAUTRE, Pharm D, Louis BUJAN, MD, Marion BENDAYAN, MD, Marius TELETIN, MD, PhD, Myriam DAUDIN, MD, Nathalie MOINARD, MD, Nathalie RIVES, MD, Nelly FRYDMAN, PharmD, PhD, Olivier BINOIS, MD, Patricia FAUQUE, MD, PhD, Pierre DI PIZIO, MD, Rachel LEVY, MD, Rahaf HAJ HAMID, MD, Sandrine GISCARD D'ESTAING, MD, PhD, Sara KOUIRI, MD, Solmaz SARANDI, MD, Solène VORILHON, MD, PhD, Sylvianne HENNEBICQU, MD, PhD, Thomas BOUEILH, MD, Virginie BARRAUD-LANGE, MD, PhD, Véronique DROUINEAUD, MD 2020-07-29
Impact Nerium Oleander on Symptoms and Mortality: A Feasibility Study Coronavirus disease 19 infection Nerium oleander proprietary extract alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) HealthQuilt Baylor College of Medicine, Texas A&M University System, The Hildebrand Fund at the Greater Houston Community Foundation, The Schull Institute, University of Maryland College Park, University of Texas Health Science Center Houston US 2020-05-20 2020-09-01 052020, NCT04486144 Phase 2 Clinical Recruiting 1 3 Months 100 Kim Dunn, MD, Ph.D. 2020-07-29
Online 1-day CBT-based Workshops for PPD Coronavirus disease 19 infection, Postnatal depression cognitive behavioural therapy based workshop alone, standard postnatal care alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) McMaster University Canada 2020-04-20 2020-12-31 NCT04485000, ONLINE1DAYCBT Phase Not Applicable Recruiting 1 8 Months 388 Ryan Van Lieshout, MD, PhD 2020-07-29
Thymalfasin (Thymosin Alpha 1) to Treat COVID-19 Infection (Ta1) Coronavirus disease 19 infection, Lymphocytopenia standard of care alone, thymalfasin alone Thymosin receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rhode Island Hospital US 2020-07-31 2021-04-30 NCT04487444, SCN-16130571-2 Phase 2 Clinical Not yet recruiting 1 9 Months 80 Eleftherios Mylonakis, MD PhD FIDSA, Fadi Shehadeh 2020-07-30
I-SPY_COVID: An Adaptive Platform Trial for Critically Ill Patients Coronavirus disease 19 infection, Respiratory distress syndrome ARDS supportive care alone, anticoagulation treatment alone, lung protective ventilation alone, Variable regimens including apremilast , cenicriviroc , icatibant , razuprotafib , remdesivir Bradykinin B2 receptor antagonist, CCR2 chemokine antagonist, CCR5 chemokine antagonist, COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, PDE 4 inhibitor, Protein tyrosine phosphatase beta inhibitor, RNA polymerase modulator, Tek tyrosine kinase receptor stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) QuantumLeap Healthcare, QuantumLeap Healthcare Collaborative, University of California San Francisco Aerpio Pharmaceuticals Inc, Columbia University, Emory University, Montefiore Medical Center, Sanford Health, University of Alabama at Birmingham, University of California San Diego, University of Colorado, Denver, US, University of Minnesota, University of Pennsylvania, University of Southern California, Wake Forest University Health Sciences, US, Yale University US 2020-07-25 2022-11-01 I-SPY-COVID, I-SPY_COVID, NCT04488081 Phase 2 Clinical Not yet recruiting 10 27 Months 1500 Carolyn Carolyn, MD, Karyn DiGiorgio, MS, Kathleen D Liu, MD, Laura Esserman, MD, Michelle Gong, MD, Paul Berger, MD, Paul Henderson, PhD 2020-07-30
LUS-COVID: Lung Ultrasound in COVID-19 Patients Coronavirus disease 19 infection invasive ventilation alone, lung ultrasound examination alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Academic Medical Center, University of Amsterdam Centre Hospitalier Universitaire Saint Pierre, Ospedale generale regionale F. Miulli, Acquaviva delle Fonti, Universita di Bari, Universita' Degli Studi Di Foggia Netherlands 2020-06-01 2020-10-31 LUS-COVID, LUS-COVID, NCT04487769 Phase Not Applicable Recruiting 1 5 Months 30 Charalampos Pierrakos, MD, Lieuwe D Bos, MD PhD, Luigi Pisani, MD, Marcus J Schultz, MD, Marcus J Schultz, MD PhD 2020-07-30
COVID-19 Phobia in Patients With Bronchiectasis During Covid-19 Pandemic Anxiety disorder, Bronchiectasis, Coronavirus disease 19 infection, Phobia Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Hacettepe University Turkey 2020-07-23 2020-12-01 GO 20/602, NCT04487873 Phase Not Applicable Not yet recruiting 1 4 Months 28 Aslıhan Cakmak, MSc, Deniz İnal-İnce, Professor, Ebru Calik-Kütükcü, PhD, Melda Saglam, PhD, Merve Firat, MSc, Naciye Vardar-Yagli, PhD 2020-07-30
COVIE-19/20: Screening for Postpartum Depression and Associated Risk Factors Among Women Who Deliver in Four Hospital in France During the COVID-19 Epidemic Coronavirus disease 19 infection, Postnatal depression Edinburgh Postnatal Depression Scale alone, Mother-to-Infant Bonding Scale alone, State-Trait Anxiety Inventory alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire D Amiens Centre Hospitalier Compiègne, Centre hospitalier de Beauvais, Hospital Center De Saint-Quentin France 2020-07-21 2021-08-31 COVIE-19/20, NCT04487171, PI2020_843_0049 Phase Not Applicable Recruiting 1 13 Months 248 Arthur FOULON, MD, Arthur Foulon, MD, MD, Xavier BENAROUS, MD 2020-07-31
ISAM-COVID: Survey on COVID-19 Airway Management Coronavirus disease 19 infection, Respiratory failure Healthy volunteers accepted Sociedad Española de Anestesiología, Reanimación y Terapéutica del Dolor Confederation of Latin American Societies of Anaesthesiology Spain 2020-04-22 2020-09-30 ISAM-COVID, ISAM-COVID, NCT04487977 Phase Not Applicable Recruiting 1 5 Months 5000 Dr. Manuel Granell Gil, Manuel Granell Gil, Manuel Granell Gil, Dr, Manuel Granell Gil, PhD 2020-07-30
Addressing COVID-19 Mental Health Problems Among US Veterans Acute stress disorder, Coronavirus disease 19 infection short video intervention alone, vignette intervention alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Research Foundation for Mental Hygiene Inc US 2020-07-06 2020-09-10 8006, NCT04484207 Phase Not Applicable Recruiting 1 2 Months 200 Doron Amsalem, MD, Yuval Neria Neria, PhD, Yuval Neria, PhD 2020-07-29
Study of acute stroke with COVID-19 Coronavirus disease 19 infection, Stroke Japan Stroke Society, Nippon Medical School Hospital Japan 2020-07-08 UMIN000041226 Phase Not Applicable Recruiting 1 100 Kazumi Kimura, Yasuhiro Nishiyama 2020-07-30
Nebulized PL for Post-COVID-19 Syndrome Coronavirus disease 19 infection, Dyspnea, Respiratory disease, Respiratory distress syndrome, Viral pneumonia nebulized platelet lysate alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Regenexx LLC US 2020-08-03 2021-12-30 NCT04487691, RGX2020-RCT01 Phase 1 Clinical Not yet recruiting 1 16 Months 40 Christopher Centeno, MD, Ehren Dodson, PhD, Neven Steinmetz, PhD 2020-07-29
A trial to evaluate sbk-001 for the treatment of SARS-CoV-2 infection (COVID-19) Coronavirus disease 19 infection sbk-001 alone Angiotensin converting enzyme 2 inhibitor Chengdu Shibeikang Biological Medicine Technology Co Ltd Phase Not Applicable Planned 0 2020-07-28
Oral Manifestations of Coronavirus Disease 2019(COVID-19) :a Multicenter Study Coronavirus disease 19 infection Young Adults (18-44 yrs) Cairo University Egypt 2020-09-15 2020-12-15 8791, NCT04487665 Phase Not Applicable Not yet recruiting 1 3 Months 50 Dina mounir elkady 2020-07-29
Immune responses in the convalescence stage of COVID-19 patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Yokohama City University Japan 2020-09-01 UMIN000041227 Phase Not Applicable Not yet recruiting 1 140 Atsushi Goto, Takeharu Yamanaka 2020-07-30
J-DESIRE: Japan COVID-19 Survey and Questionnaire in inflammatory bowel disease Anxiety disorder, Coronavirus disease 19 infection, Psychiatric disorder questionnaire survey alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Japanese Ancestry Sapporo Medical University School of Medicine Japanese Ministry of Health, Labor and Welfare Japan 2020-07-28 J-DESIRE, UMIN000041191 Phase Not Applicable Not yet recruiting 2 2500 Hiroshi Nakase, Kohei Wagatsuma 2020-07-30
CoV-Hep: Regional Anticoagulation Modalities in Continuous Venous Venous Hemodialysis in Patients With COVID-19 Coronavirus disease 19 infection, Renal injury continued venovenous hemodialysis alone, polysulfone dialyzer alone, sodium citrate plus unfractionated heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo Brazil 2020-06-29 2021-07-31 33351120.0.0000.0068, 4.081.688, CoV-Hep, NCT04487990, RBR-45kf9p, U1111-1252-0194 Phase 2 Clinical Recruiting 1 13 Months 90 Camila Rodrigues, MD, PhD, Paulo Lins, MD 2020-07-30
A clinical study of monoclonal antibody therapeutic (subcutaneous, COVID-19), Centivax for COVID-19 patients Coronavirus disease 19 infection monoclonal antibody therapeutic (subcutaneous, COVID-19), Centivax alone Centivax Inc Phase Not Applicable Planned 0 2020-07-28
A correlation study to assess the serological ELISA and virus neutralization assays in the diagnosis of covid-19 Coronavirus disease 19 infection ELISA antibody test alone, virus microneutralization assay alone GenScript Biotech Corp Phase not specified Status not specified 0 228 2020-07-28
A study to assess cPass test in detection of COVID-19 Coronavirus disease 19 infection cPass alone GenScript Corp Singapore, China Phase Not Applicable Status not specified 2 625 2020-07-29
Evaluation of the effect of Afsantin on COVID-19 Coronavirus disease 19 infection Afsantin alone, standard treatment alone Kurdistan University of Medical Sciences Iran 2020-07-10 IR.MUK.REC.1399.048, IRCT20190415043279N6 Phase 3 Clinical Recruiting 1 80 Dr. Afshin Maleki, Noshad Mohammadi, Sabah Hasani 2020-07-29
Evaluation of Convalescent Plasma Therapy for COVID-19 Patients Coronavirus disease 19 infection Convalescent plasma therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Shahid Sadoughi University of Medical Sciences and Health Services Iran 2020-09-22 IR.SSU.REC.1399.001, IRCT20200503047281N1 Phase 0 Clinical Not yet recruiting 1 40 Dr. Farzaneh Fesahat, Dr. Hossein Hadinedoushan, Dr. Masoud Mirzaei, Dr.Hossein Hadinedoushan 2020-07-29
COVID19 - Curosurf_ARDS_COV19: Trial to be conducted in more sites, with drug known to both patient and Investigator, in which patients will be assigned randomly to receive the drug or not in order to assess the efficacy and tolerability of the drug (porcine surfactant, Curosurf) in hospitalized patients with SARS-COV-19 (COVID-19 INFECTION) acute respiratory distress syndrome Coronavirus disease 19 infection, Respiratory distress syndrome Curosurf alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chiesi Farmaceutici SpA UK 2020-07-08 2020-002632-75, CLI-050000-04, COVID19 - Curosurf_ARDS_COV19 Phase 2 Clinical No longer recruiting 1 85 2020-07-31
Needs, Perceptions and Acute Stress of Healtcare Workers Caring for COVID-19 Patients in South America Acute stress disorder, Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidad Miguel Hernandez de Elche Pontificia Universidad Catolica De Chile, Universidad Catolica Santiago de Guayaquil, Universidad de Santander, University of Sao Paulo Spain, Colombia, Ecuador, Chile 2020-04-01 2020-08-30 08/04/2020, NCT04486404 Phase Not Applicable Recruiting 4 4 Months 2500 Jose J Mira, PhD 2020-07-28
A prospective, open study on off-label use of tocilizumab for the treatment of SARS-CoV-2 pneumonia in Milan, Italy Coronavirus disease 19 infection, Pneumonia tocilizumab alone ASST Fatebenefratelli Sacco Italy Phase 2 Clinical Status not specified 1 51 2020-07-28
A phase II trial to evaluate AP-003 for the treatment of patients with COVID-19 Coronavirus disease 19 infection interferon alpha-2b (COVID-19, inhaled), Altum Pharmaceuticals alone Interferon alpha ligand modulator BetterLife Pharma Inc Altum Pharmaceuticals Inc Phase 2 Clinical Planned 0 150 2020-07-27
Effect of lavender syrup on COVID-19 Coronavirus disease 19 infection, Cough lavender syrup alone, supportive treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Gorgan University of Medical Sciences Iran 2020-05-16 IR.GOUMS.REC.1399.025, IRCT20110907007511N4 Phase 3 Clinical Recruiting 1 30 Dr. Marzieh Qaraati, Marzieh Qaraati 2020-07-28
Clinical Outcome of Anti-IL6 versus Anti-IL6 Corticosteroid Combination in Patients With SARS-CoV-2 Cytokine Release Syndrome Coronavirus disease 19 infection, Systemic inflammatory response syndrome, Viral pneumonia siltuximab alone, tocilizumab alone Heat shock protein inhibitor, IL-6 receptor antagonist Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) King Faisal Specialized Hospital & Research Center Society of Critical Care Medicine Saudi Arabia 2020-07-22 2021-07-22 NCT04486521, RAC # 2201053 Phase Not Applicable Recruiting 1 12 Months 11000 Abeer AlFirm, Associate RC Data Manager, Abeer Omar, Abid Butt, MD, Eiad Kseibi, MD, Maal Abualkhair, MD, Marwa Amer, PharmD, BCPS,BCCCP, Marwa Amer, PharmD,BCPS, BCCCP, Mohammed Abujazar, MD, Mohammed Bawazeer, MD, FRCSC, FACS, Mohammed Bawazeer, MD,FRCSC,FACS, Muath Rabee, MD, Razan Alghunaim, PharmD, Syed Moazzum Khurshid, MD, Talal Dahhan, MD 2020-07-29
DISCO: Disulfiram for COVID-19 (DISCO) Trial Coronavirus disease 19 infection disulfiram (Antabuse) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of California San Francisco US 2020-09-01 2021-09-01 DISCO, DSF151837, NCT04485130 Phase 2 Clinical Not yet recruiting 1 12 Months 60 Priscilla Hsue, MD, Rada Savic, PhD, Steven G Deeks, MD, Sulggi A Lee, MD PhD 2020-07-28
BIOCOVID: Place of Circulating Biomarkers and Respiratory Eicosanoids in the Prognosis of Severe Forms of COVID-19 Pneumonia Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory tract infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Groupe Hospitalier Paris Saint-Joseph Centre Hospitalier Victor Dupouy, Versailles University Hospital France 2020-04-14 2020-10-31 BIOCOVID, BIOCOVID, NCT04485364 Phase Not Applicable No longer recruiting 1 6 Months 100 2020-07-29
A phase I trial to evaluate CoronaVac for the prevention of COVID-19 Coronavirus disease 19 infection CoronaVac alone Dynavax Technologies Corp Medigen Vaccine Biologics Corp 2020-09-30 Phase 1 Clinical Planned 0 2020-07-27
The evaluation of isotretinoin effects on treatment of COVID-19 infections Coronavirus disease 19 infection isotretinoin alone, standard of care alone Retinoic acid receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kermanshah University of Medical Sciences Iran 2020-08-22 IR.KUMS.REC.1399.288, IRCT20190624043993N3 Phase 3 Clinical Not yet recruiting 1 50 ALI akrami, Dr. Farid Najafi, Foroud Shahbazi, Maria Shirvani 2020-07-28
Effect of omega-3 on diabetic patients with covid-19 Coronavirus disease 19 infection Variable regimens including docosahexaenoic acid , eicosapentaenoic acid , hydroxychloroquine Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tehran University of Medical Sciences Iran 2020-02-20 IR.TUMS.VCR.REC.1399.440, IRCT20200511047399N1 Phase 3 Clinical No longer recruiting 1 30 Hamed Abdollahi, Mina Abdolahi 2020-07-28
Trial to Evaluate Efficacy and Safety of Nitazoxanide in the Treatment of Mild or Moderate COVID-19 Coronavirus disease 19 infection, Respiratory disease nitazoxanide (controlled-release, viral infections), Romark plus vitamin super B-complex Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Romark Laboratories LC 2020-07-30 2020-10-30 NCT04486313, RM08-3008 Phase 3 Clinical Not yet recruiting 0 3 Months 800 Stefan Comhaire 2020-07-28
A Clinical Study to Assess the Physiologic Effects of KB-109 in Patients With COVID-19 on Gut Microbiota Structure and Function Coronavirus disease 19 infection KB-109 alone, Self Supportive Care (SSC) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kaleido Biosciences Inc US 2020-07-31 2021-03-31 K032-120, NCT04486482 Phase 2 Clinical Recruiting 1 8 Months 50 Courtney Balliro, RN,BS,CDE, Mark Wingertzahn, PhD 2020-07-28
Chest Radiography in COVID‒19 Patients Coronavirus disease 19 infection, Pulmonary edema invasive ventilation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Academic Medical Center, University of Amsterdam Chonburi Hospital, Mahidol University, Universita di Bari, Universitair Ziekenhuis Brussel Netherlands 2020-08-01 2021-03-01 NCT04485338, RALE-COVID Phase Not Applicable Not yet recruiting 1 7 Months 200 Christel M. A. Valk, MSc, Claudio Zimatore, MSc, Marcus J. Schultz, Prof. 2020-07-30
A clinical trial to evaluate NurOwn for the treatment of patients with COVID-19 ARDS Coronavirus disease 19 infection, Respiratory distress syndrome NurOwn alone Brain derived neurotrophic factor ligand, Glial cell neurotrophic factor ligand BrainStorm Cell Therapeutics Inc Phase Not Applicable Planned 0 2020-07-27
CONFI-DIAB: Assessing the Impact of the COVID-19 Lockdown on Metabolic Control and Access to Health Care in Patients With Diabetes Coronavirus disease 19 infection, Diabetes mellitus Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Hospital, Nancy, France France 2020-07-31 2020-09-30 2020PI137, CONFI-DIAB, NCT04485351 Phase Not Applicable Recruiting 1 2 Months 700 Lisa Ludwig, Dr 2020-07-28
ACCESS: Safety Net Support Use in California Coronavirus disease 19 infection earned income tax credit-safety net support program alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), African Ancestry University of California at Berkeley University of California San Francisco US 2020-07-21 2022-06-30 048228-001, ACCESS, NCT04485377 Phase Not Applicable Not yet recruiting 2 23 Months 530 2020-07-28
INSPIRATION: Intermediate-dose versus Standard Prophylactic Anticoagulation and Statin versus Placebo in ICU Patients With COVID-19 Coronavirus disease 19 infection atorvastatin alone, enoxaparin sodium plus unfractionated heparin HMG CoA reductase inhibitor, Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rajaie Cardiovascular Medical and Research Center Brigham & Women's Hospital, Firuzgar hospital, Imam General Hospital, Masih Daneshvari Hospital, Modarres Hospital, Rasoul Akram Hospital, Sina Hospital, Tabriz University of Medical Sciences, Tehran Heart Center Iran, US 2020-07-30 2020-12-06 99060, INSPIRATION, NCT04486508 Phase 3 Clinical Not yet recruiting 2 4 Months 600 Behnood Bikdeli, MD, MS, Parham Sadeghipour, MD, Sara Tayyebi, MS 2020-07-30
Feasibility of a Telematics Pre-operative Assessment in a Bariatric Surgery During Covid-19 Coronavirus disease 19 infection, Obesity low calorie diet alone, telemedicine alone, very low calorie diet alone, very low calorie ketogenic diet alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Universita degli Studi di Roma La Sapienza Italy 2020-06-01 2020-07-31 66.20, NCT04486417 Phase Not Applicable Recruiting 1 2 Months 20 Gianfranco Silecchia, Gianfranco Silecchia, FULL PROFESSOR, Laura Pierro, PhD 2020-07-29
Efficacy Assessment of Methylprednisolone and Heparin in Patients With COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia enoxaparin sodium alone, methylprednisolone alone, standard treatment alone, unfractionated heparin alone, Variable regimens including enoxaparin sodium , methylprednisolone , unfractionated heparin Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto D'Or de Pesquisa Brazil 2020-07-20 2020-12-31 31180820600005249, NCT04485429 Phase 3 Clinical Recruiting 1 5 Months 268 Abel Costa Neto, MD, Eduardo M Rego, MD, PhD 2020-07-28
Evaluation of Non Invasive Ventilator Acidosis, Coronavirus disease 19 infection, Viral pneumonia BiPAP Auto Biflex Philips Respironics IN761S alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Council of Scientific and Industrial Research (India) India 2020-07-22 CTRI/2020/07/026607 Phase Not Applicable Not yet recruiting 1 10 Dr Sathyanarayana Mysore 2020-07-28
Efficacy of the early use of corticotherapy in CoV-2 infection to prevent the progression of acute respiratory distress syndrome (ARDS) Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia methylprednisolone (Pfizer) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) VHIR Vall d'Hebron Institut de Recerca Spain 2020-06-03 2020-002186-34, MP_COVID19 Phase 4 Clinical Recruiting 1 100 Ferran Martínez Valle 2020-07-28
A phase III clinical trial to study the safety and efficacy of of ChAdOx1 nCoV-19 in healthy volunteers Coronavirus disease 19 infection AZD-1222 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) University of Oxford UK 2020-05-31 Phase 3 Clinical Status not specified 1 2020-07-27
Clinical trial to evaluate the efficacy and safety of gammaglobulins in COVID-19 treatment Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure, Shock, Viral pneumonia Flebogamma 10% DIF alone, Flebogamma DIF 5% alone Beta amyloid modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) San Antonio Technologies - San Antonio Catholic University of Murcia Spain 2020-06-10 2020-001890-56, COVID-Γ Phase 4 Clinical Recruiting 1 100 Bioithas 2020-07-28
A clinical study of Avigan in Kuwait for COVID-19 treatment Coronavirus disease 19 infection favipiravir alone RNA polymerase inhibitor FUJIFILM Holdings Corp Dr Reddy's Laboratories Ltd Kuwait Phase Not Applicable Planned 1 1000 2020-07-27
Prognostic Factors in Patients Admitted to an Urban Teaching Hospital With COVID-19 Infection Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Glasgow Royal Infirmary University NHS Trust UK 2020-04-01 2021-06-01 IRAS 282807, NCT04484545 Phase Not Applicable No longer recruiting 1 14 Months 250 Donogh Maguire, PhD 2020-07-27
AbOcCov: Search for antiviral antibodies in COVID-19 patients' eye secretions Coronavirus disease 19 infection University of Ferrara Italy 2020-05-20 2020-12-31 544-2020, AbOcCov, ISRCTN17301812 Phase Not Applicable Recruiting 1 7 Months 60 Prof Caselli 2020-07-28
ESCORPIO: Controlled trial on the usefulness of pioglitazone treatment in patients with type 2 diabetes mellitus and COVID-19 Coronavirus disease 19 infection, Non-insulin dependent diabetes pioglitazone alone, standard treatment alone Insulin sensitizer, PPAR gamma agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundación Investigación Biomédica Hospital Ramón y Cajal Spain 2020-06-16 2020-001929-31, ESCORPIO, ESCORPIO Phase 4 Clinical Recruiting 1 76 Anabel Sánchez 2020-07-27
Corticosteroid Nasal Spray in COVID-19 Anosmia Coronavirus disease 19 infection, Dysomia mometasone furoate alone, olfactory training alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Benha University Egypt 2020-08-01 2020-09-01 NCT04484493, RC 4-7-2020 Phase 3 Clinical Not yet recruiting 1 1 Month 50 Abdelhakim F Ghallab, MD, Abdelrahman A Abdelalim, MD, Mona A Elawady, MD, Rasha A Elsayed, MD 2020-07-28
A clinical trial of vaccine (Dynavax adjuvant CpG1018, Bordetella pertussis infection), Serum Institute of India for the prevention of covid-19 Coronavirus disease 19 infection vaccine (Dynavax adjuvant CpG1018, Bordetella pertussis infection), Serum Institute of India alone TLR-9 agonist Dynavax Technologies Corp, Mount Sinai Medical Center, National Institute of Allergy and Infectious Diseases National Institutes of Health Phase 1 Clinical Planned 0 2020-07-24
Predictors of COVID-19 Infection and Disease Progression (Portsaiduni) Coronavirus disease 19 infection CT chest imaging alone, Rt-PCR testing alone, ancillary diagnostic test alone, clinical picture analysis alone Healthy volunteers accepted Port Said University, Egypt Egypt 2020-03-15 2020-09-15 NCT04484597, PROF. REFAT SADEQ Phase Not Applicable Recruiting 1 6 Months 100 Refat A. Sadeq, Ph D 2020-07-28
TOCICOVID: Phase III, Randomized, Unicentric, Open, Controlled Clinical Trial To Demonstrate The Effectiveness Of Tocilizumab Against Systemic Corticotherapy In Patients Entered By COVID-19 With Bilateral Pneumonia And Bad Evolution Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia tocilizumab (intravenous), Roche/Chugai alone IL-6 receptor antagonist, IL-6 receptor modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto Biodonostia Spain 2020-06-25 2020-001707-16, TOCICOVID, TOCICOVID Phase 3 Clinical Recruiting 1 60 IIS BIODONOSTIA 2020-07-27
A phase III clinical trial of SARS-CoV-2 vaccine for the treatment of COVID-19 Coronavirus disease 19 infection SARS-CoV-2 vaccine (corona virus disease 19 infection), Research Institute of Influenza alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Research Institute of Influenza Phase 3 Clinical Recruiting 0 100 2020-07-24
HUB-MdI-ICAT-COVID-201: Investigating the Efficacy and Safety Icatibant For The Treatment of Patients with SARS-CoV-2 (COVID-19) Infection Coronavirus disease 19 infection, Viral pneumonia icatibant alone Bradykinin B2 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) L'Hospitalet de Llobregat pending23 Spain 2020-07-09 2020-002166-13, HUB-MdI-ICAT-COVID-201, HUB-MdI-ICAT-COVID-201 Phase 2 Clinical Recruiting 1 120 Dr. Ramón Lleonart Bellfill 2020-07-27
SulES-COVID: Suloexide in the Treatment of Early Stages of COVID-19 Chronic obstructive pulmonary disease, Coronavirus disease 19 infection, Myocardial disease, Renal injury, Respiratory failure, Thrombosis sulodexide alone Heparin agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) CLINEDEM, Mexico Alfasigma SpA Mexico 2020-06-05 2020-08-10 CLIDM/VAS/2020-05-01, NCT04483830, SulES-COVID Phase 2/Phase 3 Clinical Recruiting 1 2 Months 250 Alejandro j Gonzalez-Ochoa, md, alejandro j Gonzalez-Ochoa, MD, alejandro j gonzalez ochoa, md 2020-07-27
amb-COVID: The state of health of ambulatory patients after COVID-19 disease Coronavirus disease 19 infection Jena University Hospital Germany 2020-08-01 2020-1834-Bef, DRKS00022498, amb-COVID Phase Not Applicable Not yet recruiting 1 1000 Ms. Dana Loudovici-Krug, Ms. Dr. med Christina Lemhöfer 2020-07-27
A study to assess clinical validation of Adeptrix COVID-19 diagnostic test Coronavirus disease 19 infection Adeptrix COVID-19 diagnostic test alone Avacta Ltd Phase Not Applicable Not yet recruiting 0 2020-07-28
CORONATION: Coronavirus (COVID-19) multinational, observational registry Coronavirus disease 19 infection Cambridge University Hospitals NHS Foundation Trust, University of Cambridge NIHR Cambridge Biomedical Research Centre UK, Estonia, France, Georgia, Latvia, Slovakia, Belarus, Switzerland, Macedonia, The Former Yugoslav Republic of, Norway, Israel, Italy, Albania, Russian Federation, Serbia, Poland, Austria, Portugal, Romania, Turkey, Netherlands, Tunisia, Belgium, Bosnia and Herzegovina, Finland, Czech Republic, Sweden, Ukraine, Spain, Denmark, Greece, Cyprus, Croatia, Bulgaria, Lithuania, Iceland 2020-04-06 2025-04-24 CCTU0304, CORONATION, IRAS 282239, ISRCTN17717312 Phase Not Applicable Not yet recruiting 38 60 Months Dr Kerrie Brusby, Dr Thomas F Hiemsra 2020-07-27
A study to assess safety of SARS-CoV-2 Spike Protein for the potential treatment of Covid-19 Coronavirus disease 19 infection TerraCoV2 vaccine (COVID-19), Noachis Terra alone COVID19 Spike glycoprotein modulator Oragenics Inc 2021-01-01 Phase 1 Clinical Planned 0 2020-07-24
SPI-1005 Treatment in Moderate COVID-19 Patients Coronavirus disease 19 infection ebselen (oral, hearing loss/bipolar disorder/ ototoxicity/Meniere disease/SARS-CoV-2 infection (COVID-19)), Sound Therapeutics alone Glutathione peroxidase stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sound Pharmaceuticals Inc US 2020-08-31 2020-12-31 NCT04484025, SPI-1005-291 Phase 2 Clinical Not yet recruiting 1 4 Months 60 Haifan Lin, PhD, Jonathan Kil, MD, Miriam Treggiari, MD 2020-07-27
The Effect of Omega-3 on Selected Cytokines Involved in Cytokine Storm Coronavirus disease 19 infection omega3 fatty acid alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Applied Science Private University Jordan 2020-08-05 2020-12-05 2020-PHA-18, NCT04483271 Phase Not Applicable Not yet recruiting 1 4 Months 100 Mahmoud S Abu-Samak, PhD, Mahmoud Suleiman Abu-Samak, Rafeef A Al-Khaled, MSC 2020-07-27
Breathing Techniques and Meditation for Health Care Workers During COVID-19 Pandemic Acute stress disorder, Coronavirus disease 19 infection, Lung disease Meditation Therapy alone, Quality-of-Life Assessment alone, Questionnaire alone, Yoga alone, breathing techniques alone Healthy volunteers accepted, Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) MD Anderson Cancer Center National Cancer Institute US 2020-06-17 2021-07-01 2020-0483, NCI-2020-04931, NCT04482647, P30CA016672 Phase 1 Clinical Recruiting 1 12 Months 50 Santhosshi Narayanan 2020-07-28
SEROBL-COVID19: COVID-19 in Baselland: Investigation and Validation of Serological Diagnostic Assays and Epidemiological Study of Sars-CoV-2 Specific Antibody Responses Coronavirus disease 19 infection ELISA tests alone, PCR testing alone, biological sampling alone, point of care (POC) assay alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Basel Department of Health, Economics and Health Directorate Canton Basel-Land, ETH Zurich Switzerland 2020-04-10 2022-05-30 BASEC PROJECT-ID 2020-00816, NCT04483908, SEROBL-COVID19 Phase Not Applicable Recruiting 1 25 Months 550 Carlos Quinto, Dr. med., Miodrag Savic, Dr. med. 2020-07-27
CORIVER: Ivermectin as antiviral treatment for patients infected by SARS-COV2 (COVID19) Coronavirus disease 19 infection, Viral pneumonia ivermectin alone Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hospital Universitario Virgen de las Nieves Spain 2020-06-02 2020-001971-33, CORIVER, CORIVER Phase 3 Clinical Recruiting 1 45 Sergio Sequera 2020-07-29
MADRID-COVID: MADRID-COVID Coronavirus disease 19 infection, Respiratory distress syndrome metoprolol tartrate (Beloken) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto de Investigación Sanitaria de la Fundacion Jimenez Diaz Spain 2020-06-15 2020-002310-41, MADRID-COVID, MADRID-COVID Phase 2 Clinical Recruiting 1 20 NOEMI ESCALERA 2020-07-27
Tele-rehabilitation Versus Home Exercise Program in COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome Home exercise alone, Remote controlled exercise alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Koc University Turkey 2020-08-31 2022-08-31 2020.219.IRB1.069, NCT04482634 Phase Not Applicable Not yet recruiting 1 24 Months 122 Baris Ata, Prof, Ihsan Solaroglu, Prof, Mahir Topaloglu, MD, Ozden Ozyemisci Taskiran, Prof, Zeynep Turan, MD 2020-07-28
Effect of two covers to prevent injuries caused to professionals working in the health area due to the use of personal protective equipment Coronavirus disease 19 infection, Decubitus ulcer cover based on polyurethane foam alone, cover with extra-fine hydrocolloid coating alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidade Estadual de Campina Fundo de apoio ao ensino, à pesquisa e extensão - Faepex Brazil 31786020.0.0000.5404, RBR-7drpyr Phase Not Applicable No longer recruiting 1 88 Renata Cristina Gasparino 2020-07-28
Study to Evaluate Pharmacokinetic (PK), Safety and Tolerability of Cabotegravir 400 mg/ml Formulation in Healthy Adult Participants Coronavirus disease 19 infection, HIV infection cabotegravir (long-acting injectable, HIV prevention), ViiV alone, cabotegravir (oral), ViiV Healthcare alone HIV integrase inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) ViiV Healthcare Ltd 2020-08-07 2022-04-27 212482, NCT04484337 Phase 1 Clinical Not yet recruiting 0 20 Months 124 EU GSK Clinical Trials Call Center, GSK Clinical Trials, US GSK Clinical Trials Call Center 2020-07-27
Use of Technology and Telemedicine to Improve Quality of Care in COVID-19 Patients Coronavirus disease 19 infection Doctorgram Mobile Application alone, Doctorgram Patient Kit alone, Remote Pulse Oximeter alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Stanford University US 2020-08-31 2021-02-28 56472, NCT04480411 Phase Not Applicable Not yet recruiting 1 6 Months 165 Julieta M Gabiola, MD, Lisa Shieh, MD, Nicholas Scoulios, MD, Ritu Parikh, MD 2020-07-28
Impact of Covid-19 on Frequent Social Interaction Through Communication Technologies in the Cognitive Status of Socially-isolated Older Adults Amnesia, Cognitive disorder, Coronavirus disease 19 infection Technology based social interactions alone Healthy volunteers accepted Boston University US 2020-08-31 2021-05-31 H-26786, NCT04480112 Phase Not Applicable Not yet recruiting 1 9 Months 150 Andrew E Budson, MD, Andrew E Busdon, MD, Rocco Pallumbo, PhD 2020-07-29
SPI-1005 Treatment in Severe COVID-19 Patients Coronavirus disease 19 infection ebselen (oral, hearing loss/bipolar disorder/ ototoxicity/Meniere disease/SARS-CoV-2 infection (COVID-19)), Sound Therapeutics alone Glutathione peroxidase stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sound Pharmaceuticals Inc US 2020-08-31 2020-12-31 NCT04483973, SPI-1005-292 Phase 2 Clinical Not yet recruiting 1 4 Months 60 Haifan Lin, PhD, Jonathan Kil, MD, Miriam Treggiari, MD 2020-07-27
PROTECT: Preventing COVID-19 With High-dose Vitamin D Supplements Coronavirus disease 19 infection vitamin D alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) CHU de Quebec-Universite Laval Canadian Institutes of Health Research, Laboratoire Riva Inc Canada 2020-09-01 2021-06-30 MP-21-2021-3044, NCT04483635, PROTECT Phase 3 Clinical Not yet recruiting 2 10 Months 2414 Annie Chamberland, Annie Theoret, Annie Théoret, Cecile Tremblay, MD, Francine M Ducharme, MD, Francine M Ducharme, MD, M.Sc. 2020-07-27
The Change of Critical Patient Managements and Subsequent Influences Under Epidemic of Coronavirus Disease 19 (COVID-19) Acute stress disorder, Coronavirus disease 19 infection, Surgical procedure Negative Pressure Isolation Room alone, Resuscitation Area alone, Tracheal intubation alone, cardiopulmonary resuscitation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Taiwan University Hospital Taiwan 2020-08-01 2022-07-31 202005094RIND, NCT04479332 Phase Not Applicable Not yet recruiting 1 24 Months 334 Min-Shan Tsai, MD 2020-07-28
COVID-19: Immunoglobulin G Antibody Immune Response Profile Following Infection With SARS-CoV-2 in COVID-19 Egyptian Patients Coronavirus disease 19 infection, Immune disorder RT-PCR assay alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sohag University Egypt 2020-06-12 2021-02-15 COVID-19, IBR#S20-133, NCT04483622 Phase Not Applicable Recruiting 1 8 Months 30 Asmaa Mohamed Goda, Asmaa m Goda, MD, asmaa m goda, MD 2020-07-27
Safety, Tolerability and Pharmacokinetics of SCTA-01, an Anti-SARS-CoV-2 Monoclonal Antibody, in Healthy Chinese Subjects Coronavirus disease 19 infection SCTA-01 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry Sinocelltech Ltd China 2020-07-24 2021-01-15 NCT04483375, SCTA01-X101 Phase 1 Clinical Recruiting 2 5 Months 33 Ji Qi, PhD, Qing Liu, MSc, Wang Xinghe, PhD, Xinghe Wang, MD,PhD 2020-07-30
PRE-COVID: Pilot trial on early treatment with hydroxychloroquine in patients with COVID-19 who do not have hospital admission at diagnosis Coronavirus disease 19 infection, Viral pneumonia hydroxychloroquine alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidade de Santiago de Compostela Spain 2020-06-15 2020-002449-41, PRE-COVID, PRE-COVID Phase 3 Clinical Recruiting 1 340 ANTONIO ANTELA LOPEZ 2020-07-27
SilCOVID19: Randomized clinical trial to test if silibinin administration can prevent the respiratory failure secondary to the COVID-19 lung infection in oncological patients Coronavirus disease 19 infection, Lung infection, Respiratory failure Legalon alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto Catalan de Oncologia Girona Biomedical Research Institute Spain 2020-06-10 2020-001794-77, SilCOVID19, SilCOVID19 Phase 2 Clinical Recruiting 1 92 Clinical Research Unit 2020-07-28
SchoolCoviDD19: Prospective SARS-CoV-2 seroprevalence study of school children after the lockdown March 2020 (COVID-19) Coronavirus disease 19 infection blood sampling alone, manuscript alone, questionnaire alone University Hospital Carl Gustav Carus Germany 2020-05-18 BO-EK-156042020, DRKS00022455, SchoolCoviDD19 Phase Not Applicable No longer recruiting 1 600 Jakob Armann 2020-07-27
Epidemiological Characteristics of an Outbreak of 2019 Novel Coronavirus Diseases (COVID-19) in the Petaling District: A Descriptive Study Coronavirus disease 19 infection PEJABAT KESIHATAN BAHAGIAN KUCHING Malaysia 2020-08-01 NMRR-20-1540-55803 Phase Not Applicable Not yet recruiting 1 rama krishna a/l supramanian 2020-07-29
Perceptions about Ethics of Public Health Behavioral Interventions during the Covid 19 Outbreak Coronavirus disease 19 infection behaviorial changes alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institutes of Health (NIH), Ministry of Health Malaysia Malaysia 2020-08-01 NMRR-20-1542-55843 Phase not specified Not yet recruiting 8 Asyraf Syahmi Bin Mohd Noor 2020-07-29
Comparison of PCR versus antigen from various sample types as diagnostic test in COVID-19 infection Coronavirus disease 19 infection Antigen detection alone, PCR assessment alone Hospital Sungai Buloh Malaysia 2020-08-01 55639, NMRR-20-1569-55639 Phase not specified Not yet recruiting 1 31 Syarifah Nurul Ain Bt Syed Badaruddin 2020-07-27
EXCEL: Exercise for Cancer to Enhance Living Well Cancer, Coronavirus disease 19 infection Group Exercise alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Calgary Alberta Health Services, Dalhousie University, Memorial University, The University Health Network, University of Alberta, University of British Columbia, University of Prince Edward Island Canada 2020-08-01 2027-12-31 EXCEL, HREBA.CC-20-0098, NCT04478851 Phase Not Applicable Not yet recruiting 3 89 Months 1500 Julianna Dreger, M.ClinExPhys, Margaret L McNeely, PhD, Melanie Keats, PhD, Nicole Culos-Reed, PhD 2020-07-28
Fourth Trimester - A Web-based Tool for Postpartum Care to Address the Needs of Underserved Women Anxiety disorder, Coronavirus disease 19 infection, Postnatal depression Fourth Trimester Mobile Tool alone Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) HealthCore Inc, New England Research Institutes National Institute on Minority Health and Health Disparities, Orange Square Design, Inc. US 2020-07-06 2020-09-22 NCT04475718, R43MD014923 Phase Not Applicable Recruiting 2 2 Months 85 Juli Leonard, Julia Coleman, Kristine Merz, Lisa Marceau, MPH 2020-07-29
Combined Simultaneous EGD-colonoscopy Trial (CoSi Endoscopy) Colonoscopy, Coronavirus disease 19 infection A Fuji Lasereo 7000 alone, Olympus Evis Exera II alone, Simultaneous EGD and colonoscopy alone, colonoscopy alone, esophagogastroduodenoscopy (EGD) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Emura center Latinoamerica Universidad de la Sabana Colombia 2020-06-13 2020-09-15 2020-ECL-6-1, NCT04473456 Phase Not Applicable Recruiting 1 3 Months 40 FABIAN EMURA, FABIAN EMURA, PhD, Luis Giraldo, PhD 2020-07-30
ZSAC: Zurich Coronavirus Cohort: an observational study to determine long-term clinical outcomes and immune responses after coronavirus infection (COVID-19), assess the influence of virus genetics, and examine the spread of the coronavirus in the population of the Canton of Zurich, Switzerland Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Zurich Switzerland 2020-05-01 2022-09-30 ISRCTN14990068, ZSAC Phase Not Applicable Not yet recruiting 1 29 Months 2200 Dr Dominik Menges, Dr Dominik Menges, MPH, Dr Tala Ballouz, Prof Alexandra Trkola, Prof Christian Münz, Prof Jan Fehr, Prof Milo A. Puhan, Prof Roger Kouyos 2020-07-27
Building Family Caregiver Skills Using a Simulation-Based Intervention for Care of Cancer Patients Anal tumor, Colorectal tumor, Coronavirus disease 19 infection, Esophagus tumor, Larynx tumor, Metastatic head and neck cancer, Mouth tumor, Nasopharyngeal carcinoma, Non-small-cell lung cancer one-on-one teaching sessions alone, telephone booster contact alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Case Comprehensive Cancer Center National Institutes of Health US 2019-12-01 2023-04-30 CASE4Y19, NCT04055948 Phase Not Applicable Recruiting 1 41 Months 180 Susan Mazanec, PhD, Susan Mazanec, v 2020-07-29
The effects of Favipiravir and Lopinavir/Ritonavir in treatment COVID-19 Coronavirus disease 19 infection Interferon beta-1a (CinnaGen, Iran) plus favipiravir(Zhejiang Hisun, China) Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bandare-abbas University of Medical Sciences Iran 2020-07-25 IR.HUMS.REC.1399.225, IRCT20200506047323N3 Phase 3 Clinical Recruiting 1 60 Mahdi Hasani Azad, Mohammad Fathalipour, Teamur Aghamolaei 2020-07-27
Pat-steps Coronavirus disease 19 infection, Psychiatric disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Selayang Hospital Malaysia 2020-08-03 2020-10-30 NMRR-20-1538-55653 Phase Not Applicable Not yet recruiting 1 2 Months 146 Dr Son Wei Da 2020-07-28
Inconsistent RdRp gene detection causing false negative COVID-19 PCR Coronavirus disease 19 infection Teluk Intan Hospital Malaysia 2020-07-20 2020-07-27 55881, NMRR-20-1533-55881 Phase Not Applicable No longer recruiting 1 Dr Yong Jo Yen 2020-07-27
Preoperative Immature Granulocyte Count and Percentage for Acute Appendicitis Appendicitis, Coronavirus disease 19 infection Appendectomy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kahramanmaras Sutcu Imam University Turkey 2018-06-01 2019-06-01 180, NCT04440150 Phase Not Applicable Completed 1 12 Months 70 Mehmet Buğra Bozan 2020-07-27
SKILLZ: Reaching 90 90 90 in Adolescents in Zambia: Using All Our SKILLZ Coronavirus disease 19 infection, HIV infection SKILLZ-Girl Enhanced football curriculum alone Healthy volunteers accepted, Female, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Alabama at Birmingham Centre for Infectious Disease Research in Zambia, Grassroot Soccer (GRS), University of California San Francisco, Washington University School of Medicine, US Zambia 2020-03-01 2023-06-30 IRB-300002251, NCT04429061, SKILLZ Phase Not Applicable Recruiting 1 40 Months 3200 Carolyn Bolton, Carolyn Bolton, MPH, MD, Carolyn Dr Bolton, MPH, MD, Nancy Dr Padian, MPH, MD 2020-07-29
COGMA: Computerized Cognitive Training in Middle-Aged Adults With Generalized Anxiety Disorder: A Pilot Study Coronavirus disease 19 infection, Generalized anxiety disorder computerized cognitive Training alone Healthy volunteers accepted, Middle-aged Adults (45-64 yrs) University of Missouri US 2020-06-08 2021-05-31 2021943, COGMA, NCT04421690 Phase Not Applicable Recruiting 1 11 Months 30 Ashley Curtis, PhD, Jacob Wilhelm 2020-07-27
@LIITCI: Low Intensity Internet Therapy for Chronic Illness Anxiety disorder, Coronavirus disease 19 infection, Depression Acceptance and Commitment Therapy alone, Compassion-Focused Therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Coimbra Portugal 2020-05-01 2021-08-31 @LIITCI, LIIT, NCT04408651 Phase Not Applicable No longer recruiting 1 16 Months 54 Inês A Trindade 2020-07-27
Telerehabilitation in Disabled People: Proposal for Practical Intervention With Virtual Reality Coronavirus disease 19 infection Application of tele-rehabilitation alone Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Sao Paulo Brazil 2020-05-15 2020-11-01 03851012.7.0000.5390, NCT04402034 Phase Not Applicable Recruiting 1 5 Months 40 Carlos BM Monteiro, Ph.D., Carlos BM Monteiro, PhD, Talita D Silva, PhD 2020-07-28
Intervention for Caregivers of Patients Undergoing HSCT or CAR T-cell Therapy Anxiety disorder, Coronavirus disease 19 infection Psychoeducation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Case Comprehensive Cancer Center US 2020-07-17 2021-02-28 CASE8Z20, NCT04390542 Phase Not Applicable Not yet recruiting 1 7 Months 40 Sara Douglas, PhD, RN 2020-07-27
Stress and Anxiety Levels of Mothers Lying in the Baby Newborn Intensive Care Unit Anxiety disorder, Coronavirus disease 19 infection survey work alone Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Eskisehir Osmangazi University Turkey 2020-07-25 2020-12-25 DSAYIK1, NCT04386798 Phase Not Applicable Not yet recruiting 1 5 Months 60 AYFER ACIKGOZ, assoc. dr., DILEK SAYIK, expert nurse, OZLEM MUMCU, OZLEM MUMCU, expert nurse 2020-07-27
PARK-NU: Positive Affect Regulation skills at Northwestern University Anxiety disorder, Coronavirus disease 19 infection, Depression Positive Emotion Skills Course alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Northwestern University US 2020-04-27 2021-02-28 NCT04367922, PARK-NU, STU00212262 Phase Not Applicable Recruiting 1 10 Months 1000 Amanda Summers, MA, Judith Moskowitz, PhD 2020-07-27
Yoga in NHS Health Care Workers With COVID-19 Related Stress Acute stress disorder, Coronavirus disease 19 infection, Generalized anxiety disorder Zoom platform alone, online group session alone, sudarshan kriya yoga session alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Doncaster and Bassetlaw Hospitals NHS Foundation Trust UK 2020-07-01 2021-02-01 DBH 1058/2020/HRAS, NCT04481516 Phase Not Applicable Recruiting 1 7 Months 30 Emma Adams, Rachel Codling, Venkat D Nagarajan 2020-07-27
Social Anxiety Telehealth Therapy Study Coronavirus disease 19 infection, Social phobia Coordinated Anxiety Learning and Management (CALM) program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Stanford University US 2020-09-01 2021-07-01 56697, NCT04450303 Phase Not Applicable Not yet recruiting 1 10 Months 25 Tali Ball, PhD 2020-07-30
Evaluation of the Physical Activity Level of the Elderly in Social Isolation Coronavirus disease 19 infection Home exercise program alone Healthy volunteers accepted, Aged Adults (65-79 yrs), Elderly Adults (80 and over) Istinye Universitesi 2020-08-01 2020-11-20 008, NCT04480606 Phase Not Applicable Not yet recruiting 0 3 Months 88 2020-07-28
RAPA-CARDS: Effects of mTOR Inhibition With Sirolimus (RAPA) in Patients With COVID-19 to Moderate the Progression of ARDS Acute lung injury, Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia sirolimus alone mTOR inhibitor Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Texas Health Science Center San Antonio Johns Hopkins Claude D. Pepper Older Americans Independence Center US 2020-10-31 2022-10-31 HSC20200489H, NCT04482712, RAPA-CARDS Phase 1/Phase 2 Clinical Not yet recruiting 2 24 Months 20 Dean L Kellogg, MD, PhD 2020-07-23
Sero-Epidemiology of SARS-COV2 infection in the Autonomous city of Buenos Aires Coronavirus disease 19 infection anti-SARS-CoV-2 antibody test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ministerio de Salud de Ciudad Autónoma de Buenos Aires Argentina 2020-07-31 2020-10-31 NCT04482361, SEROEPIDEMIOLOGY COVID IN CABA Phase Not Applicable Not yet recruiting 1 3 Months 5400 Alejandro Macchia, MD, Daniel Ferrante, MD 2020-07-27
Survey about knowledge towards blood donation during COVID 19 pandemic Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Kasturba Medical College, Manipal Manipal Academy of Higher Education India 2020-07-21 CTRI/2020/07/026559 Phase Not Applicable Not yet recruiting 1 500 Deepika Chenna 2020-07-24
Neem Prophylaxis for Subjects Coming in Contact with COVID-19 Patients Coronavirus disease 19 infection Neem Capsules (Azadirachta indica) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Nisarga Biotech Pvt Ltd India 2020-07-21 CTP/NB/03/20, CTRI/2020/07/026560 Phase 3 Clinical Not yet recruiting 1 200 Dr Mohini Barde, Prof Tanuja Manoj Nesari 2020-07-24
Comparison of two devices for intubation in COVID simulated scenario in mannequin Coronavirus disease 19 infection Touren non channeled videolaryngosocpe with a styletted tube alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Medical Sciences India 2020-06-02 CTRI/2020/06/025522 Phase Not Applicable Not yet recruiting 1 50 Anju Gupta 2020-07-23
Safety and efficacy of Ayurvedic capsule in mild to moderate COVID-19 infection Coronavirus disease 19 infection, Influenza virus infection, Pneumonia Cap. IP alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) AMAI Charitable Trust India 2020-07-15 CTRI/2020/07/026570 Phase Not Applicable Not yet recruiting 1 60 Dr Hrishikesh Rangnekar, Dr Kishor H Suryawanshi, Dr Suresh Patankar 2020-07-27
VitD-COVID19: Vitamin D Supplementation in the Prevention and Mitigation of COVID-19 Infection Coronavirus disease 19 infection, Vitamin D deficiency Vitamin D3 alone Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Medical University of South Carolina Grassroots Health Nutrition Institute, ZRT Laboratory US 2020-07-20 2021-12-30 00099939, NCT04482673, VitD-COVID19 Phase 4 Clinical Recruiting 1 17 Months 140 Carol L Wagner, MD, Carole Baggerly, Jeffrey Korte, PhD, John E Baatz, PhD, Renee O Washington, MS 2020-07-24
CTC: CoYoT1 to California Coronavirus disease 19 infection, Diabetes mellitus CoYoT1 Care alone Adolescents (13-17 yrs), Young Adults (18-44 yrs) Children's Hospital of Los Angeles Rutgers University, University of Southern California US 2019-01-20 2020-12-31 CHLA-18-00488, CTC, NCT03793673 Phase Not Applicable Recruiting 1 23 Months 80 Alejandra Torres Sanchez, BA, Jaquelin J Flores Garcia, BS, Jennifer K Raymond, MD, MCR 2020-07-27
Universal versus Targeted School Screening for Adolescent Major Depressive Disorder Coronavirus disease 19 infection, Major depressive disorder universal screening arm alone Milton S. Hershey Medical Center Health Resources and Services Administration, Patient Centered Outcome Research Institute US 2018-07-01 2020-12-31 NCT03716869, R40MC31765, STUDY00010090 Phase Not Applicable Recruiting 1 30 Months 17300 Deepa Sekhar, MD 2020-07-27
Mindful Self Compassion for Combat Deployed Veterans With Moral Injury and Co-occurring PTSD-SUD Coronavirus disease 19 infection, Drug dependence, Post traumatic stress disorder Mindful Self-Compassion alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) VA Office of Research and Development Providence VA Medical Center, Rhode Island US 2019-05-21 2021-03-31 1I21RX002893-01A1, D2893-P, NCT03681288 Phase Not Applicable Recruiting 1 22 Months 24 Christy Capone, PhD, Erica M Eaton, PhD, Erica M. Eaton, PhD 2020-07-27
A phase II trial to evaluate COVID-EIG the potential treatment or prevention of SARS-CoV-2 infection (COVID-19) Coronavirus disease 19 infection COVID-EIG alone Emergent BioSolutions Inc Phase 2 Clinical Planned 0 2020-07-23
A phase II trial to evaluate COVID-HIG for the potential treatment or prevention of SARS-CoV-2 infection (COVID-19) Coronavirus disease 19 infection COVID-HIG alone Emergent BioSolutions Inc Phase 2 Clinical Planned 0 2020-07-23
COVID-19 and changes in the heart Cardiovascular disease, Coronavirus disease 19 infection, Viral pneumonia azithromycin alone, fluoroquinolone alone, hydroxychloroquine alone, sotalol alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sri Jayadeva Institute of Cardiovascular Sciences and Research India 2020-05-19 CTRI/2020/07/026698 Phase Not Applicable Not yet recruiting 1 3000 Dr Jayaprakash Shenthar 2020-07-28
EMPOWER: Enhancing and Mobilizing the POtential for Wellness and Emotional Resilience Among Surrogate Decision-Makers of ICU Patients Coronavirus disease 19 infection EMPOWER alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Weill Medical College of Cornell University Memorial Sloan-Kettering Cancer Center, National Cancer Institute, The New York Hospital Medical Center of Queens US 2017-07-12 2021-05-31 1610017622, EMPOWER, NCT03276559, R21CA218313 Phase Not Applicable Recruiting 3 46 Months 155 Holly G Prigerson, Ph. D., Martin Viola, M.A., Wendy Lichtenthal, Ph. D., Wendy Lichtenthal, PhD 2020-07-23
Infant Mental Health-Home Visiting Randomized Controlled Trial Coronavirus disease 19 infection, Psychiatric disorder Infant Mental Health-Home Visiting alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Michigan Michigan, State of, Health and Human Services, Department of Health and Human Services US 2017-10-12 2020-09-30 HUM00124224, NCT03175796 Phase Not Applicable No longer recruiting 1 35 Months 144 Katherine Rosenblum, PhD 2020-07-27
MBCT Delivered Via Group Videoconferencing for ACS Syndrome Patients With Depressive Symptoms Acute coronary syndrome, Coronavirus disease 19 infection, Depression Mindfulness-Based Cognitive Therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Massachusetts General Hospital US 2020-04-24 2021-01-02 2020P000045, NCT04231097 Phase Not Applicable Recruiting 1 8 Months 20 Christina Luberto, PhD, Christina M Luberto, PhD, Elyse Park, PhD, MPH 2020-07-27
PHOSP-COVID: Long-term follow up of adults hospitalized with COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Leicester United Kingdom Research & Innovation, University Hospitals of Leicester National Health Service Trust UK 2020-04-15 2046-12-31 CPMS 46443, IRAS 285439, ISRCTN10980107, PHOSP-COVID Phase Not Applicable Recruiting 44 320 Months 10000 Prof Brightling 2020-07-27
Ayurvedic Rasayana therapies Coronavirus disease 19 infection pranvir plus yasada rasayana Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Ayurved Rasayani India 2020-07-27 CTRI/2020/07/026700 Phase Not Applicable Not yet recruiting 2 200 Dr Avinash Kadam 2020-07-27
Management of endotracheal intubation in critically ill patients with novel coronavirus pneumonia (COVID-19) and clinical characteristics: a medical records based study Coronavirus disease 19 infection The First Affiliated Hospital of college of medicine Zhejiang University China 2020-07-15 2020-07-31 ChiCTR2000034852 Phase Not Applicable Recruiting 1 14 Fuquan Fang, Xianhui Kang 2020-07-27
Phase I/II Ascending Dose Study of Investigational SARS-CoV-2 Vaccine ARCT-021 in Healthy Adult Subjects Coronavirus disease 19 infection LUNAR-COV19 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Arcturus Therapeutics Inc, CTI Clinical Trial and Consulting Services Singapore 2020-07-31 2021-01-31 ARCT-021-01, NCT04480957 Phase 1/Phase 2 Clinical Not yet recruiting 1 6 Months 85 Connie Crowley, Jenny Low Guek Hong, MD, Michellore Aguilar, Steve Hughes, MD 2020-07-29
Knowledge, Attitude and Practice towards COVID-19 among Kerala Residents during the outbreak period:an online, cross-sectional survey Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Govt Medical College India 2020-08-01 CTRI/2020/07/026728 Phase Not Applicable Not yet recruiting 1 140 DR Venugopalan AK 2020-07-23
Mind Your Mate: The Mind Your Mate Study: A randomized, controlled trial of an online peer intervention to prevent mental health and substance use problems in adolescents Coronavirus disease 19 infection, Drug dependence, Psychiatric disorder Mind your Mate alone Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs) University of Sydney Australian Rotary Health Australia 2020-07-22 2021-12-17 ACTRN12620000753954, Mind Your Mate Phase Not Applicable Not yet recruiting 1 16 Months Dr Louise Birrell 2020-07-27
Scanning of lungs, heart and blood vessels by two different techniques using ultrasound in COVID-19 patients Coronavirus disease 19 infection ultrasonography alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Narayana Health India 2020-07-23 CTRI/2020/07/026701 Phase Not Applicable Not yet recruiting 1 80 Dr Muralidhar Kanchi 2020-07-27
Liver function test used as a tool to determine severity of COVD 19 pneumonia – A Prospective, observational study Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Medical Sciences India 2020-07-30 CTRI/2020/07/026727 Phase Not Applicable Not yet recruiting 1 100 Nishant Patel 2020-07-27
Structured online training program on specific COVID-19 Airway Management Coronavirus disease 19 infection Structured online training program alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) AIIMS Rishikesh India 2020-07-31 CTRI/2020/07/026715 Phase Not Applicable Not yet recruiting 1 1000 Bhavna Gupta 2020-07-23
Psychological Impact of COVID 19 on Healthcare Workers Anxiety disorder, Coronavirus disease 19 infection, Depression, Insomnia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) CARE Hospital India 2020-08-03 CTRI/2020/07/026714 Phase Not Applicable Not yet recruiting 1 100 Dr Harini Atturu 2020-07-27
A Phase I clinical trial of novel coronavirus pneumonia (COVID-19) mRNA Vaccine (BNT-162b1) in China Coronavirus disease 19 infection BNT-162b1 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry BioNTech RNA Pharmaceuticals GmbH, Jiangsu Province Centers for Disease Control and Prevention, Shanghai Fosun Pharmaceutical Industry Development Co Ltd China 2020-07-20 2020-12-31 ChiCTR2000034825 Phase 1 Clinical Recruiting 2 5 Months 144 Wang Wei, Zhu Fengcai 2020-07-27
Efficacy and safety of AYUSH 64 tablets in treating mild to moderate Covid 19 patients Coronavirus disease 19 infection AYUSH 64 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Central Council for Research in Ayurveda and Siddha India 2020-07-28 CTRI/2020/07/026705 Phase 1 Clinical Not yet recruiting 2 80 Dr Nataraj H R 2020-07-27
Covid-19 Pandemic: Economic Burden on Patients Operated for Traumatic Close Fractures Bone injury, Cancer, Coronavirus disease 19 infection, Degeneration elective surgery alone, operative fracture management intervention alone Aga khan University Pakistan 2020-03-16 2020-05-31 AKUPDE, NCT04482205 Phase Not Applicable Completed 1 2 Months 840 Pervaiz Hashmi, FCPS, shah fahad 2020-07-28
WW2COVID-19: Results of Emotional Support Activities During Hospital Admission With a Diagnosis of COVID19 Anxiety disorder, Coronavirus disease 19 infection nursing emotional supportive activity care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Corporacion Parc Tauli Spain 2020-09-30 2020-12-31 2020664, NCT04481477, WW2COVID-19 Phase Not Applicable Not yet recruiting 1 3 Months 450 Jordi Torralbas, MSc, Montserrat Montaña, PhD 2020-07-27
A clinical trial of HDT-301 for the prevention of Coronavirus disease 19 infection in healthy volunteers Coronavirus disease 19 infection HDT-301 alone COVID19 Spike glycoprotein inhibitor Healthy volunteers accepted American Association for the Advancement of Science, University of Washington HDT Bio, National Institutes of Health, Washington National Primate Research Center, Wellcome Trust - Burroughs Wellcome Fund Phase 1 Clinical Planned 0 2020-07-27
PREDICTCovid19: Development and Validation of a Prediction Model for the Transition From Mild to Moderate Form of COVID-19, Using Data From Chest CT Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Bordeaux France 2020-08-01 2020-10-31 CHUBX 2020/23, NCT04481620, PREDICTCovid19 Phase Not Applicable Not yet recruiting 7 3 Months 1315 Annaïg OZIER, MD, Arnaud BOURDIN, MD, PhD, Francois Laurent, MD, PhD, François CHABOT, MD, PhD, Gilbert FERRETTI, MD, PhD, Julien CASTEIGT, MD, Maeva Zysman, MD, Rémy GUILLEVIN, MD, PhD 2020-07-24
SEROCO: COVID-19 Serological Status of Hospital Staff Working or Not in the COVID-19 Sector Coronavirus disease 19 infection serological screening alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Limoges France 2020-08-15 2021-01-15 87RI20_0049/SEROCO, NCT04481529, SEROCO Phase Not Applicable Not yet recruiting 4 5 Months 1000 Julio BADIE, MD, Laurent FOURCADE, MD 2020-07-27
WWCOVID-19: Emotional Support and Stress Management in Patients Diagnosed With COVID-19 Anxiety disorder, Coronavirus disease 19 infection training video alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Corporacion Parc Tauli Spain 2020-09-30 2020-12-31 2020663, NCT04482023, WWCOVID-19 Phase Not Applicable Not yet recruiting 1 3 Months 150 Jordi Torralbas, MSc, Montserrat Montaña, PhD 2020-07-24
DigiVis: Self-testing Vision App for Telephone Consultations Coronavirus disease 19 infection, Vision disorder DigiVis visual acuity app alone, visual acuity self-test alone Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cambridge University Hospitals NHS Foundation Trust UK 2020-07-24 2021-01-01 IRAS196573, NCT04482387 Phase Not Applicable Not yet recruiting 1 5 Months 250 Louise Allen, Louise E Allen, MBBS MD, Nabil Uddin, Stephen E Kelleher 2020-07-24
Trial of Combination Therapy to Treat COVID-19 Infection Coronavirus disease 19 infection Variable regimens including doxycycline , ivermectin , vitamin C , vitamin D3 , zinc Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) ProgenaBiome Topelia Therpeutics US 2020-08-31 2023-01-31 NCT04482686, PRG-049 Phase 2 Clinical Not yet recruiting 1 29 Months 300 Jordan Daniels, MS, Sabine Hazan, MD, Thomas Borody, MD 2020-07-31
DART: Decitabine for Coronavirus (COVID-19) Pneumonia - Acute Respiratory Distress Syndrome (ARDS) Treatment Acute lung injury, Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia decitabine alone, standard of care alone Cytosine DNA methyltransferase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Johns Hopkins University US 2020-07-29 2021-07-31 DART, IRB00247544, NCT04482621 Phase 2 Clinical Recruiting 1 12 Months 40 Franco D'Alessio, M.D, Franco D'Alessio, M.D., Joby Mathew, DPT, MS, Katrina Bazemore 2020-07-24
A Trial of Aclaris Therapeutics, Inc ATI-450 in Patients With Moderate-severe Novel Coronavirus Disease 2019 (COVID-19) Coronavirus disease 19 infection, Hypoxia, Respiratory failure ATI-450 alone Adapter molecule crk inhibitor, MAPKAPK2 inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Kansas Medical Center Aclaris Therapeutics Inc US 2020-07-31 2022-07-31 IIT-2020-ATI-450-COVID-19, NCT04481685 Phase 2a Clinical Not yet recruiting 1 24 Months 36 Deepika Polineni, M.D., M.P.H, Gregory Gan, Kimberly Lovell 2020-07-24
RAPA-501-Allo Off-the-Shelf Therapy of COVID-19 Coronavirus disease 19 infection, Respiratory insufficiency RAPA-501 alone, standard-of-care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rapa Therapeutics Hackensack Meridian Health US 2020-09-30 2021-12-31 NCT04482699, RAPA-501-ALLO-COVID-19 Phase 1/Phase 2 Clinical Not yet recruiting 1 15 Months 88 Daniel Fowler, M.D., Jennifer Gough Clinical Regulatory Coordinator 2020-07-24
BIO-300 Oral Suspension in Discharged COVID-19 Patients Coronavirus disease 19 infection, Lung injury genistein (oral suspension, radiotherapy-induced toxicity/ in SARS-CoV-2 infection (COVID-19)/pulmonary fibrosis), Humanetics alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Humanetics Corp NYU Langone Health, National Institute of Allergy and Infectious Diseases US 2020-09-30 2022-07-31 272201800011C-P00005-9999-1, CL0105-01, NCT04482595 Phase 2 Clinical Not yet recruiting 1 22 Months 66 Michael D Kaytor, Ph.D., Rany Condos, MD 2020-07-27
A trial to evaluate SLV-213 for the treatment of patients with COVID-19 Coronavirus disease 19 infection SLV-213 alone Cysteine protease inhibitor Selva Therapeutics Inc Phase Not Applicable Planned 0 2020-07-28
PREPCOV: Efficacy of Pre-exposure Treatment With Hydroxychloroquine on the Risk and Severity of COVID-19 Infection Coronavirus disease 19 infection hydroxychloroquine alone, Variable regimens including azathioprine , hydroxychloroquine , methotrexate Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire de Toulouse France 2020-09-30 2020-09-30 2020-A01906-33, NCT04481633, PREPCOV, RC31/20/0186 Phase 4 Clinical Not yet recruiting 12 800 Adeline RUYSSEN-WITRAND, Pr, Anne-Laure FAUCHAIS, Pr, Arnaud CONSTANTIN, Pr, Carle PAUL, PR, Carle PAUL, Pr, Christina LIVIDEANU, DR, David RIBES, Dr, Dominique CHAUVEAU, Pr, Edouard LARREY, Dr, Estibaliz LAZARO, Pr, Francis GACHES, Dr, Georges-Philippe PAGEAUX, Pr, Gregory PUGNET, Pr, Guillaume MOULIS, Dr, Jean-François VIALLARD, Pr, Kim LY, Dr, Laurent ALRIC, Pr, Laurent SAILLER, Pr, Marie IRLES-DEPE, Dr, Martin MICHAUD, Pr, Mathieu VAUTIER, Dr, Pascal LEBRAY, Dr, Patrice CACOUB, P, Patrice CACOUB, Pr, Stéphanie FAURE, Dr, Victor DE LEDINGHEN, Pr 2020-07-27
Evaluation of Clinical Characteristics and Outcome of COVID-19 Pneumonia in Assiut University Hospital Coronavirus disease 19 infection, Viral pneumonia chest CT alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assiut University Egypt 2020-08-31 2021-09-30 NCT04481360, PRESENTATION OF COVID19 IN AUH Phase Not Applicable Not yet recruiting 1 13 Months 100 Marina Omil Saman, Marina Saman, Mostafa kamal, Safaa Mokhtar 2020-07-24
A trial to evaluate PneumoBlast for the treatment of patients with COVID-19 Coronavirus disease 19 infection PneumoBlast alone FibroGenesis US Phase Not Applicable Planned 1 2020-07-23
COVMASK: Novel Face Mask Sampling for COVID-19: A Diagnostic and Public Health Tool Coronavirus disease 19 infection 3D printed Polyvinyl alcohol face mask (University of Leicester) alone, face mask sampling alone Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Leicester University Hospitals of Leicester National Health Service Trust UK 2020-06-12 2025-06-30 0775, COVMASK, NCT04481646 Phase Not Applicable Recruiting 1 60 Months 630 Caroline Williams, MbChB, Manish Pareek, Manish Pareek, MBChB PhD 2020-07-24
PrimeRisk C-19: COVID-19 in primary care: assessment of risk factors and predictors for severe courses Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Styrian Academy of General Medicine Karl Landsteiner University of Health Sciences Austria 2020-07-16 1046/2020, DRKS00022448, PrimeRisk C-19 Phase Not Applicable Recruiting 1 300 Susanne Rabady 2020-07-28
MaZeCO: Patients with Breast Cancer in Times of COVID-19 Acute stress disorder, Breast tumor, Coronavirus disease 19 infection, Psychiatric disorder breast cancer-specific questionnaires alone, serum / plasma analysis alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Wurzburg Germany 2020-04-30 70/20 Amendment, DRKS00022507, MaZeCO Phase Not Applicable Recruiting 1 200 Catharina Bartmann 2020-07-28
GeZeCO: Birth in Times of COVID-19 Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression bio-sample analysis alone, questionnaires alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) University of Wurzburg Germany 2020-04-16 70/20, DRKS00022506, GeZeCO Phase Not Applicable Recruiting 1 300 Catharina Bartmann 2020-07-28
NEUROSIVIR: Safety, Tolerability and Pharmacokinetics of Inhaled Nanoparticle Formulation of Remdesivir (GS-5734) and NA-831 Coronavirus disease 19 infection, Neuritis, Neurodegenerative disease, Respiratory tract infection, Viral pneumonia remdesivir alone, traneurocin (Alzheimer's disease), NeuroActiva alone, remdesivir plus traneurocin (Alzheimer's disease), NeuroActiva AMPA receptor modulator, COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) NeuroActiva Inc US 2020-09-15 2021-03-31 NCT04480333, NEUROSIVIR, NEUROSIVIR Phase 1 Clinical Recruiting 1 6 Months 45 Brian Tran, MD, David Nguyen, MD, Lloyd Tran, PhD, Markku Kurkinen, PhD 2020-07-24
Survey of Coronavirus disease 2019(COVID-19) Coronavirus disease 19 infection fact-finding survey alone School of Medicine, Keio University Japan 2020-05-29 UMIN000041186 Phase Not Applicable Recruiting 1 2000 Koichi Fukunaga, Makoto Ishii 2020-07-28
Sexual Health and Problems During the Covid -19 Infection Coronavirus disease 19 infection, Sexual dysfunction questionaire alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Aljazeera Hospital Al-Azhar University Egypt 2020-06-11 2020-07-12 MARITAL HEALTH, NCT04427813 Phase Not Applicable Not yet recruiting 1 1 Month 400 Ahmed Elgazzar, M.D, Mahmoud Alalfy, PhD, Mahmoud Alalfy, master 2020-07-24
COVIDCIR: Complications and Mortality Following Emergency Digestive Surgery During the COVID-19 Pandemic Coronavirus disease 19 infection, Surgical procedure gastrointestinal surgery alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Universitari de Bellvitge Institut Investigació Biomèdica Bellvitge Spain 2020-03-01 2020-08-31 COVIDCIR, COVIDCIR, NCT04479150 Phase Not Applicable Recruiting 1 6 Months 3000 Javier Osorio, MD, PhD, Zoilo Madrazo, MD 2020-07-24
PLASMA: Therapeutic Plasmapheresis in Critically Ill Adult Patients With COVID-19 Confirmed Diagnosis Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia ABO compatible convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundacion Cardiovascular de Colombia Colombia 2020-08-01 2022-08-31 CEI-2020-01200, NCT04480632, PLASMA Phase 2 Clinical Not yet recruiting 1 25 Months 44 Claudia Colmenares, MD, Norma Serrano, MD 2020-07-24
Possible Predictors of Mortality Based on COVID-19 for Patients Under 50 Years Old: A Multicenter Experience of Istanbul Coronavirus disease 19 infection PCR alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Istanbul Bakirkoy Maternity and Children Diseases Hospital Turkey 2020-03-10 2020-07-14 KSSEAH--PPC, NCT04479137 Phase Not Applicable Completed 1 4 Months 5000 Ramazan Guven 2020-07-24
Bee-Covid: The Use of Brazilian Green Propolis Extract (EPP-AF) in Patients Affected by COVID-19 Coronavirus disease 19 infection Brazilian Green Propolis extract alone, antibiotic therapy alone, antiviral therapy alone, corticosteroid therapy alone, extracorporeal membrane oxygenation alone, invasive supplemental oxygenation alone, non-invasive supplemental oxygenation alone, renal replacement therapy alone, vasopressor support alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto D'Or de Pesquisa Hospital Sao Rafael Brazil 2020-06-02 2020-08-30 31099320.6.0000.0048, Bee-Covid, NCT04480593 Phase 2/Phase 3 Clinical Recruiting 1 2 Months 120 Marcelo Silveira, MD, PhD, Suzete Farias, MD, PhD 2020-07-30
Post COVID-19 Functional Status in Egypt Coronavirus disease 19 infection Assiut University Egypt 2020-07-01 2020-11-30 ASSIUTU16, NCT04479293 Phase Not Applicable Recruiting 1 5 Months 400 Aliaa AR Hussein, Aliae AR Mohamed Hussein 2020-07-24
Study to Evaluate the Safety and Efficacy of High Dose Intravenous Immune Globulin (IVIG) Plus Standard Medical Treatment (SMT) Versus SMT Alone in Participants in Intensive Care Unit (ICU) With Coronavirus Disease (COVID-19) Coronavirus disease 19 infection Gamunex alone, standard medical treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Grifols Therapeutics Inc, USA US 2020-07-31 2021-02-28 GC2007, NCT04480424 Phase 2 Clinical Not yet recruiting 1 7 Months 100 Elsa Mondou, MD, Rhonda Griffin, Simon Mahler, MD 2020-07-24
A clinical study of VLP vaccine for the potential treatment of Covid-19 Coronavirus disease 19 infection VLP vaccine (Vaxrex, COVID-19), Metaclipse Therapeutics alone Metaclipse Therapeutics 2021-12-31 Phase Not Applicable Planned 0 2020-07-29
The effect of Cyclosporine in prognosis and clinical improvement in patients with COVID-19 Coronavirus disease 19 infection, Respiratory tract infection ciclosporin, Novartis alone, routine treatment alone Calcineurin inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Hamadan University of Medical Sciences Iran 2020-07-22 IR.UMSHA.REC.1399.355, IRCT20200426047206N3 Phase 3 Clinical Recruiting 1 48 Behshad Naghshtabrizi, Dr Fariba Keramat, Saeed Bashirian, Salman Khazaei 2020-07-27
Safety, Tolerability, and Pharmacokinetics Study of Human Monoclonal Antibody BRII-196 Coronavirus disease 19 infection BRII-196 alone COVID19 Spike glycoprotein inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Brii Biosciences TSB Therapeutics (Beijing) CO.LTD China 2020-07-12 2021-03-31 BRII-196-001, NCT04479631 Phase 1 Clinical Recruiting 1 8 Months 12 Lili Chen, Yao Zhang 2020-07-27
Extracorporeal Blood Purification as a Treatment Modality for COVID-19 Blood clotting disorder, Coronavirus disease 19 infection, Inflammatory disease, Viral pneumonia Prismaflex oXiris system alone, continuous venovenous hemodiafiltration alone, continuous venovenous hemofiltration alone, extracorporeal blood purification therapy alone, oXiris (AN69ST) hemofilter (Baxter) alone, slow continuous ultrafiltration alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Zan Mitrev Clinic 2020-06-01 2021-07-01 EBPZ.357, NCT04478539 Phase Not Applicable Recruiting 0 13 Months 35 Dashurie Neziri, MD, Dijana Popevski, MD, Petar A Ugurov, MD, Rodney A Rosalia, PhD, Zan K Mitrev, MD 2020-07-23
Evaluation of Coagulopathy in Critically Ill COVID-19 Patients Blood clotting disorder, Coronavirus disease 19 infection Sonclot Analyzer SCP1 (Sienco) alone Assiut University Egypt 2020-07-20 2020-08-31 NCT04479280, TRRRE Phase Not Applicable Recruiting 1 1 Month 50 Rasha Hamed, rasha hamed, MD 2020-07-23
Pegylated Interferon-alfa-2b With SARSCoV- 2 (COVID-19) Coronavirus disease 19 infection Standard of Care alone, peginterferon alfa-2b follow-on-biologic, Zydus-Cadila alone Interferon alpha 2 ligand Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Zydus Cadila Healthcare Ltd, Zydus-Cadila Group Mexico 2020-08-05 2021-01-30 NCT04480138, PEGI.20.003 Phase 2 Clinical Not yet recruiting 1 5 Months 40 Dr Deven Parmar, MD, Dr Richa Vellanki 2020-07-25
A case study to evaluate the efficacy of AlloRx Stem Cells for the treatment of critically ill COVID-19 patient Coronavirus disease 19 infection AlloRx Stem Cells alone Vitro Diagnostics Inc Phase Not Applicable Status not specified 0 1 Dr. Prabhat Soni 2020-07-30
A Phase I/II clinical trial of multitope peptide-based vaccine (COVID-19), Covaxx for the prevention of Covid-19 Coronavirus disease 19 infection multitope peptide-based vaccine (COVID-19), Covaxx alone Covaxx University of Nebraska Medical Center US Phase 1/Phase 2 Clinical Planned 1 2020-07-28
Prevention of Severe COVID-19 in Infected Elderly by Early Administration of Convalescent Plasma With High-titers of Antibody Against SARS-CoV2 Coronavirus disease 19 infection COVIDAR IgG (Insituto Leloir, Argentina) alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundacion Infant Argentina 2020-06-04 2020-07-30 FUNDACIONINFANT-PLASMA, NCT04479163 Phase 2 Clinical Recruiting 7 1 Month 210 Anibal Rondan, MD, Fernando P Polack, MD, Gonzalo Perez Marc, MD, Ivonne Ritou, MD, Jorge Lantos, MD, Maximiliano De Zan, MD, Pablo Cruz, MD, Romina P Libster, MD, Valeria Fernandez Viña, MD 2020-07-23
SARS-Brazil: Brazilian Registry for Clinical Presentation of Individuals With COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sociedade Beneficente Israelita Brasileira Hospital Albert Einsten Ministry of Health, Brazil Brazil 2020-07-31 2021-02-28 30047620.3.0000.0071, NCT04479488, SARS-Brazil Phase Not Applicable Recruiting 9 7 Months 2000 Adriano Pereira, PhD, Alexandre P Tognon, PhD, Aline T Soares, PhD, Diogo Moia, Eveline P Milan, PhD, Felipe Pisa, PhD, Henrique A Fonseca, PhD, Henrique A. Fonseca, PhD, Mauro Esteves, PhD, Otávio Berwanger, PhD, Priscila A Martins, PhD 2020-07-31
A phase I clinical trial of multitope peptide-based vaccine (COVID-19), Covaxx for the prevention of Covid-19 Coronavirus disease 19 infection multitope peptide-based vaccine (COVID-19), Covaxx alone Covaxx Taiwan 2020-08-31 Phase 1 Clinical Planned 1 2020-07-28
Does COVID-19 Pandemic Reduce In-hospital Mortality? Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Istanbul Bakirkoy Maternity and Children Diseases Hospital Turkey 2020-03-11 2020-06-30 KSSEAH--IHM, NCT04480515 Phase Not Applicable Completed 1 3 Months 5000 Ramazan Guven 2020-07-23
Safety, Tolerability, and Pharmacokinetics Study of Human Monoclonal Antibody BRII-198 Coronavirus disease 19 infection BRII-198 alone COVID19 Spike glycoprotein inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Brii Biosciences TSB Therapeutics (Beijing) CO.LTD China 2020-07-13 2021-03-31 BRII-198-001, NCT04479644 Phase 1 Clinical Recruiting 1 8 Months 12 Lili Chen, Yao Zhang 2020-07-27
A longitudinal serological surveillance study using the Project Covalence trial platform Coronavirus disease 19 infection Harvard TH Chan School of Public Health Phase Not Applicable Recruiting 0 2020-07-24
Microbial Infection and AMR in Hospitalized Patients With COVID-19 Coronavirus disease 19 infection, Infectious disease Assiut University Egypt 2020-07-24 2020-12-31 MICROBIAL INFECTION WITH COVID, NCT04479982 Phase Not Applicable Not yet recruiting 1 5 Months 70 ALShymaa faheem solyman ali, Alshymaa Ali, PHD 2020-07-23
COVIDEP: Assessment of the Risk of Pulmonary Embolism and Coagulation Profile in Patients With COVID-19 Lung Disease Coronavirus disease 19 infection, Lung disease, Lung embolism, Viral pneumonia systematic thoracic angiography scanning alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopital Foch Hôpital Ambroise Paré, University Hospital, Brest France 2020-05-26 2020-08-31 2020_0058, COVIDEP, NCT04479540 Phase Not Applicable Recruiting 1 3 Months 120 Christine FOULON, Colas TCHERAKIAN, MD, Colas Tcherakian, MD, Isabelle BUFFET 2020-07-25
COVIDOSE-2: Low-dose Tocilizumab Versus Standard of Care in Hospitalized Patients With COVID-19 Coronavirus disease 19 infection, Inflammatory disease, Viral pneumonia tocilizumab alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Chicago US 2020-08-05 2021-03-01 COVIDOSE-2, IRB20-1179, NCT04479358 Phase 2 Clinical Not yet recruiting 1 6 Months 332 Garth W Strohbehn, MD, MPhil, Pankti D Reid, MD, MPH 2020-07-22
Experience of an Emergency Intensive Care Unit During COVID-19 Pandemic Coronavirus disease 19 infection PCR test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Istanbul Bakirkoy Maternity and Children Diseases Hospital Turkey 2020-03-10 2020-07-14 KSSEAH--EDCC, NCT04480060 Phase Not Applicable Completed 1 4 Months 100000 Ramazan Guven 2020-07-24
A Double-Blind, Randomized, Placebo-Controlled, Phase I, Single-Dose, Dose-Escalating Trial of Long-Acting Recombinant Human IL-7 (NT-I7) for COVID-19 Coronavirus disease 19 infection NT-I7 alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) National Institute of Allergy and Infectious Diseases National Institutes of Health Clinical Center US 2020-07-23 2021-12-31 20-I-0140, 200140, NCT04476290 Phase 1 Clinical Recruiting 2 17 Months 60 Andre Kalil, M.D., Andrea Lisco, M.D., Irini Sereti, M.D. 2020-07-24
PRON-COVID: Prone Positioning in Non-intubated Patients With COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome Awake prone positioning alone, Standard oxygen therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Civil de Guadalajara Mexico 2020-05-03 2020-12-30 048/20, NCT04477655, PRON-COVID Phase Not Applicable Recruiting 2 7 Months 200 Guadalupe Aguirre-Avalos, MD, José A López-Pulgarín, MD, Miguel A Ibarra-Estrada, MD, Miguel Ibarra-Estrada, Miguel Marín-Rosales, PhD, Quetzalcóatl Chávez-Peña, MD, Roxana García-Salcido, MD, Sara A Aguirre-Díaz, MD 2020-07-28
COVID-BF: COVID-19 Breastfeeding Guideline for African-Americans Coronavirus disease 19 infection COVID-19 Breastfeeding Support alone Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), African Ancestry Meharry Medical College US 2020-09-30 2022-06-30 330875, COVID-BF, NCT04476940 Phase Not Applicable Not yet recruiting 1 21 Months 200 Allysceaeioun D Britt, Ph.D., MPH., Carlton Z Adams, M.D., Flora A Ukoli, M.D., MPH., Gwinett Ladson, M.D., Jacinat Leavell, Ph.D., MS, Kimberley Wyche-Etheridge, M.D., Samuel E Adunyah, Ph.D., Tao Lu, Ph.D. 2020-07-28
BOIFIM: The Effect of Berberine on Intestinal Function and Inflammatory Mediators in Severe Patients With Covid-19 Coronavirus disease 19 infection, Gastrointestinal disease, Inflammatory disease, Viral pneumonia Antibiotic therapy alone, Antiviral drugs alone, General support therapy alone, Glucocorticoid therapy alone, Oxygen therapy alone, berberine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) chinese medical association China 2020-02-08 2020-04-23 BERBERINE TREATS COVID-19, BOIFIM, NCT04479202, XJ2020005101 Phase 4 Clinical Completed 1 2 Months 76 Wenkui Yu, M.D. 2020-07-23
Online Delivery of Psychotherapy, Tailored to Patients' Suffering From Mental Health Problems Due to COVID-19 Acute stress disorder, Coronavirus disease 19 infection, Generalized anxiety disorder, Major depressive disorder e-Psychotherapy - Online Psychotherapy Tool (OPTT) alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Queen's University Online PsychoTherapy Clinic Canada 2020-06-15 2021-05-31 NCT04476667, PSIY-683-20 Phase Not Applicable Recruiting 1 11 Months 80 Nazanin Alavi 2020-07-28
A global clinical trial investigating the use of CT-P59 in people in close contact with COVID-19 patients Coronavirus disease 19 infection CT-P59 alone COVID19 Spike glycoprotein inhibitor, Moesin modulator Celltrion Healthcare Co Ltd Phase Not Applicable Planned 0 2020-07-22
A Phase II/III clinical trial of CT-P59 for the treatment of mild and moderate COVID-19 patients Coronavirus disease 19 infection CT-P59 alone COVID19 Spike glycoprotein inhibitor, Moesin modulator Celltrion Healthcare Co Ltd Phase 2/Phase 3 Clinical Planned 0 2020-07-22
A Phase I clinical trial of CT-P59 for the treatment of mild COVID-19 patients Coronavirus disease 19 infection CT-P59 alone COVID19 Spike glycoprotein inhibitor, Moesin modulator Celltrion Healthcare Co Ltd Europe, UK Phase 1 Clinical Planned 1 2020-07-22
Healthy Lifestyle or Pro-health Obsession During the Pandemic Coronavirus disease 19 infection, Psychiatric disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gdansk University of Physical Education and Sport Beijing Sport Uninversity, Catholic University of the Sacred Heart, Clinical Hospital Center, Split, Institut Catholique de Paris, Instituto Piaget, International University of Business Agriculture and Technology, Jagiellonian University, Klaipėda University, Kyivs'kyi Natsional'nyi Universytet Imeni Tarasa Shevchenka, Norwegian School of Sport Sciences, Universidad Pablo de Olavide, Universidade Évora, Universitas Padjadjaran, Universitatea Alexandru Ioan Cuza, University Of Gdansk, University of Brasilia, University of Gondar, University of Nigeria, University of Peradeniya - Sri Lanka, University of Sargodha, University of Social Welfare and Rehabilitation Sciences, Vietnam National University, Wright State University Bangladesh, China, Indonesia, Norway, South Africa, Germany, Poland, Vietnam, Italy, Spain, Sri Lanka, India, Croatia, Pakistan, Canada, Japan, Ethiopia, Romania, Nigeria, France, Brazil, Lithuania, Portugal, US, Russian Federation, Iran 2020-06-19 2021-06-30 GDANSKUPES, NCT04432038 Phase Not Applicable Recruiting 26 12 Months 50000 Mariusz Lipowski, Prof., Mariusz Lipowski, prof. 2020-07-27
COVID-19 Lessons Learned: the Outcome of TOMEKA Project is to Teach (MD) Coronavirus disease 19 infection TOMEKA alone, nutrition education alone Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Kinshasa Universitaet Gent, Universite De Montreal Congo, The Democratic Republic of the 2020-09-01 2021-09-01 NCT04424940, TSHIMA GUYGUY KABUNDI, UKINSHASA Phase Not Applicable Not yet recruiting 1 12 Months 800 GUYGUY K. TSHIMA, Dr., GUYGUY KABUNDI TSHIMA, MD, TSHIMA, MD 2020-07-23
The Impact of COVID-19 Pandemic to Trauma Patients in Emergency Department: A Multicenter, Experience of Istanbul Coronavirus disease 19 infection, Injury COVID-19 PCR alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Istanbul Bakirkoy Maternity and Children Diseases Hospital Turkey 2020-03-10 2020-07-14 KSSTHR—TPED, NCT04479124 Phase Not Applicable Completed 1 4 Months 2000 Ramazan Guven, Proffessor 2020-07-23
RASCALS: Rapid Assay for Sick Children With Acute Lung Infection Study Coronavirus disease 19 infection, Lower respiratory tract infection, Lung infection rapid pathogen detection assay alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) Cambridge University Hospitals NHS Foundation Trust UK 2020-04-06 2025-02-28 277039, NCT04233268, RASCALS Phase Not Applicable Recruiting 1 58 Months 250 Nazima Pathan, FRCPCH PhD 2020-07-23
Efficacy and Safety of Guduchi Ghan Vati for Covid-19 Asymptomatic Patients Coronavirus disease 19 infection Guduchi Ghan Vati alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Aarogyam UK Dr.S R.Rajasthan Ayurved University Jodhpur India 2020-05-12 2020-07-03 AYU/DSSR/02, NCT04480398 Phase Not Applicable Completed 1 1 Month 91 Abhimanyu Kumar, Jaydeep Joshi, Neha Sharma, Parashar Sharma 2020-07-29
Knowledge, Attitude and Practice of Gastrointestinal Endoscopists Toward PPE in COVID-19 Era Coronavirus disease 19 infection online questionnaire alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assiut University Egypt 2020-07-31 2020-09-30 COVID ENDOSCOPY, NCT04479345 Phase Not Applicable Not yet recruiting 1 2 Months 100 Haidi Karam 2020-07-23
Impact of Botox Treatment Into the Upper One Third of the Face an Area on Mood and Self -Appearance Satisfaction Coronavirus disease 19 infection, Dermatological disease onabotulinumtoxinA alone Acetylcholine receptor antagonist, p130Cas associated protein inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) DeNova Research US 2020-07-15 2020-10-15 BTX-PST-COVID, NCT04439825 Phase 1 Clinical Not yet recruiting 1 3 Months 45 2020-07-23
Decision Support System Algorithm for COVID-19 Diagnosis Coronavirus disease 19 infection, Viral pneumonia RT-PCR alone, thorax CT alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ankara University Turkey 2020-08-31 2021-08-31 09081, NCT04479319 Phase Not Applicable Not yet recruiting 1 12 Months 10000 Dr.Ozlem Ozdemir Kumbasar, Özlem Özdemir Kumbasar, Prof Dr 2020-07-23
Seroprevalence of SARS-Cov-2 in the Setting of a Non-dedicated COVID-19 Hospital in a Low CoV-2 Incidence Area: Implications for Surgery Coronavirus disease 19 infection RT PCR alone, serological tests alone Universita degli Studi di Cagliari Italy 2020-03-30 2020-06-30 COVID-SURG, NCT04480580 Phase Not Applicable Completed 1 3 Months 100 Fabio Medas 2020-07-23
ARTI-19: An observational study to evaluate the clinical efficacy of Artemisinin in mild and moderate COVID-19 patients Coronavirus disease 19 infection Artemisinin alone Mateon Therapeutics Inc Tanzania ARTI-19 Phase Not Applicable Planned 1 Dr. Amos Kahwa 2020-07-22
Obesity Surgery During 2020 Italian Pandemic Coronavirus disease 19 infection, Obesity R-en-Y gastric bypass alone, anastomosis gastric bypass alone, heparin alone, single anastomosis duodeno-ileal bypass with sleeve alone, sleeve gastrectomy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Universita degli Studi di Roma La Sapienza Azienda Ospedaliera Citta della Salute e della Scienza di Torino, Azienda Ospedaliera di Padova, Azienda Ospedaliero Universitaria Santa Maria della Misericordia, Azienda Ospedaliero, Universitaria Pisana, Humanitas Clinical and Research Center, IRCCS Policlinico San Donato, Policlinico S.Orsola-Malpighi, University of Rome Tor Vergata Italy 2020-07-15 2021-05-30 008758/27.05.2020, NCT04480034 Phase Not Applicable Not yet recruiting 1 10 Months 1600 Alessandra Papa, Cristian E Boru, Dr, Gianfranco Silecchia, Gianfranco Silecchia, Prof 2020-07-24
A clinical trial of StemVacs, Emvolio for the treatment of Coronavirus disease 19 infection Coronavirus disease 19 infection StemVacs, Emvolio alone Therapeutic Solutions International Inc Phase Not Applicable Planned 0 2020-07-22
A clinical study of A. annua extracts for the treatment of Covid-19 Coronavirus disease 19 infection A. annua extract alone ArtemiLife Inc US Phase Not Applicable Planned 1 2020-07-22
NICOR: Nitric Oxide Therapy for COVID-19 Patients With Oxygen Requirement Coronavirus disease 19 infection, Hypoxia nitric oxide alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Federal State Budgetary Scientific Institution, Research Institute of Cardiology Russian Federation 2020-07-17 2021-09-17 8322/1, NCT04476992, NICOR Phase 1/Phase 2 Clinical Not yet recruiting 1 14 Months 20 Nikolay O Kamenshchikov, M.D., Nikolay O. Kamenshchikov 2020-07-23
Detection of Influenza or SARS-CoV-2 Infection by IMS of Nasal Air Sampling Coronavirus disease 19 infection, Influenza virus infection multicapillary Ion mobility spectrometry alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Klinikum Bayreuth Klinik und Institut für Nuklearmedizin Germany 2020-02-15 2020-06-30 IMS 1, NCT04282135 Phase Not Applicable Completed 1 4 Months 76 Claus Steppert, MD 2020-07-23
PREDICT-COVID: Prognostication of Recovery in Early Disorders of Consciousness After COVID-19 Coma, Consciousness disorder, Coronavirus disease 19 infection functional MRI alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Massachusetts General Hospital US 2020-07-01 2023-03-30 2020P001616, NCT04476589, PREDICT-COVID Phase Not Applicable Recruiting 1 32 Months 100 Brian L Edlow, MD, Brian L. Edlow, M.D, Brian L. Edlow, M.D., David Fischer, MD 2020-07-23
TOCIDEX: Comparison of Tocilizumab Plus Dexamethasone versus Dexamethasone for Patients With Covid-19 Coronavirus disease 19 infection, Viral pneumonia dexamethasone plus tocilizumab Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris INSERM 2020-07-16 2021-12-31 2020-001246-18, APHP200375-TOCIDEX, NCT04476979, TOCIDEX Phase 2 Clinical Not yet recruiting 0 17 Months 120 Olivier HERMINE, PU-PH, Xavier MARIETTE, PU-PH 2020-07-23
A phase I/II clinical trial of artesunate for the treatment of covid-19 Coronavirus disease 19 infection artesunate alone ArtemiLife Inc Phase Not Applicable Planned 0 2020-07-22
Perceived Impact of the COVID-19 Pandemic on Medical Management and Symptoms in a High Risk Group Coronavirus disease 19 infection, Respiratory failure noninvasive ventilation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopitaux Universitaires De Geneve Switzerland 2020-06-30 2020-08-31 2020-01509, NCT04477473 Phase Not Applicable Recruiting 1 2 Months 100 Jean-Paul Janssens, M.D, Jean-Paul Janssens, M.D. 2020-07-24
Canakinumab MAP in COVID-19 Pneumonia With CRS Coronavirus disease 19 infection, Systemic inflammatory response syndrome, Viral pneumonia canakinumab alone Immunoglobulin G1 agonist, Interleukin-1 beta ligand inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Novartis AG CACZ885D2001M, NCT04476706 Phase Not Applicable Recruiting 0 Novartis Pharmaceuticals 2020-07-24
Covid-Fisetin: Pilot in Covid-19 of Fisetin to Alleviate Dysfunction and Inflammation Coronavirus disease 19 infection, Inflammatory disease fisetin alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mayo Clinic, Minnesota US 2020-07-31 2021-07-31 20-003936, Covid-Fisetin, NCT04476953 Phase 2 Clinical Recruiting 1 12 Months 70 James L Kirkland 2020-07-24
A phase III clinical trial of R-107 in the treatment of patients with COVID-19 infection Coronavirus disease 19 infection R-107 alone Kalytera Therapeutics Inc US Department of Health and Human Services Phase 3 Clinical Planned 0 2020-07-21
Abatacept for Patients With COVID-19 and Respiratory Distress Coronavirus disease 19 infection, Respiratory distress syndrome abatacept alone Cytotoxic T-lymphocyte protein-4 stimulator, T cell surface glycoprotein CD28 inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Beth Israel Deaconess Medical Center Boston Children's Hospital, Brigham & Women's Hospital, Bristol-Myers Squibb Co US 2020-08-31 2020-P-00XXX, NCT04477642 Phase 1/Phase 2 Clinical Terminated 2 Jacalyn Rosenblatt, MD 2020-07-24
Long-Term Experience and Health Effects of COVID-19 Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Altura LLC US 2020-07-01 2022-07-01 ALTCOVID-192020, NCT04477902 Phase Not Applicable Recruiting 1 24 Months 50000 Michael Wukelic, MD, Pete Fronte, MBA, Study Support 2020-07-30
CROWN: Ambulatory Management of Moderate-to-High Risk COVID Patients: The Coronavirus-Related Outpatient Work Navigators Protocol Coronavirus disease 19 infection Northwell CROWN program alone, physician-guided home-care protocol alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Northwell Health Inc US 2020-04-27 2020-12-31 20-0618, CROWN, NCT04476602 Phase Not Applicable Recruiting 1 8 Months 500 Gita Lisker, MD, Ramona Ramdeo, Ramona ramdeo 2020-07-22
The Bioequivalence Study of Umifenovir 200 mg Capsule (Atabay, Turkey) Under Fasting Conditions (Umifenovir) Coronavirus disease 19 infection Atafenovir (Atabay Kimya Sanayi Ticaret AS) alone Healthy volunteers accepted, Male, Young Adults (18-44 yrs), European Ancestry Atabay Kimya Sanayi Ticaret A.S. Farmagen Ar-Ge Biyot. Ltd. Sti, Novagenix Bioanalytical Drug R&D Center Turkey 2020-07-09 2020-08-20 NCT04476719, NOV2020/01918 Phase 1 Clinical No longer recruiting 2 1 Month 18 Muradiye Nacak, MD,PhD, Taner Ezgi, MD 2020-07-22
RAID-CoV-2: Reducing Asymptomatic Infection With Vitamin D in Coronavirus Disease Coronavirus disease 19 infection, Vitamin D deficiency Vitamin D (Pure Encapsulations) alone Healthy volunteers accepted, Young Adults (18-44 yrs) Royal Centre for Defence Medicine Leeds Beckett University, University of Nottingham UK 2020-09-01 2021-04-28 1062MODREC20, NCT04476680, RAID-CoV-2 Phase Not Applicable Not yet recruiting 1 7 Months 4400 David R Woods, MD, John O'Hara, PhD, Jonathan S Nguyen-Van-Tam, MD, Julie P Greeves, PhD 2020-07-22
Stress-Related Disorders in Family Members of COVID-19 Patients Admitted to the ICU Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder, Respiratory failure Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Colorado, Denver, US Brigham & Women's Hospital, Columbia University, Evergreen Hospital Multiple Sclerosis Center, Johns Hopkins University, Pennsylvania State University, South Shore Hospital, Tulane University, University of Vermont, Washington University in St Louis US 2020-06-29 2020-12-31 20-1021, NCT04476914 Phase Not Applicable Recruiting 9 6 Months 250 Don McGuirl, BA, J. Randall Curtis, MD, MPH, Jennifer Chiurco, MD, Karin Halvorsen, MD, Karin Halvorson, MD, Laura Fonseca, Lauren Jodi Van Scoy, MD, Marc Moss, MD, Masami Kelly, Masami Kelly, MA, Matt Baldwin, MD, May Hua, MD, Melanie Ambler, MSc, Nick Csikesz, Nick Csikesz, MD, Pamela Witt, Priscilla Armstrong, Priscilla Priscilla Armstrong, Rachel Bernacki, Rachel Hammer, MD, Renee D Stapleton, MD, PhD, Renee Stapleton, MD, Sarah Hochendoner, MD, Sarah Rhoads, MD, Timothy Amass, MD,ScM, Timothy H Amass, MD, ScM, Trevor Lane, MD, Zara Cooper, MD 2020-07-22
COLLATE: Convalescent Plasma Treatment in COVID-19 Coronavirus disease 19 infection, Multiple organ failure, Respiratory failure, Septic shock steroid therapy alone, supportive care alone, Variable regimens including azithromycin , convalescent plasma , tocilizumab Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Aga khan University Pakistan 2020-04-26 2020-09-30 COLLATE, CON000000000880, NCT04476888 Phase 2 Clinical Recruiting 1 5 Months 100 Muhammad Hasan, Muhammad Hasan, MBBS, FCPS, Muhammad Hasan, MBBS,FCPS, Natasha Ali, FCPS, MSc 2020-07-24
RUXO-COVID: Ruxolitinib for Acute Respiratory Disorder Syndrome Due to COVID-19 Coronavirus disease 19 infection, Respiratory disorder, Respiratory distress syndrome, Viral pneumonia ruxolitinib alone Jak1 tyrosine kinase inhibitor, Jak2 tyrosine kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo Brazil 2020-07-17 2021-12-31 32894720.3.0000.0068, NCT04477993, RUXO-COVID Phase 2/Phase 3 Clinical Recruiting 1 17 Months 200 Ana C Cordeiro, MD, Bruna DG Carvalho, Bruno G Baldi, MD.PhD, Carlos VP Jardim, MD.PhD, Eduardo Rego, MD.PhD, Esper Kallas, MD.PhD, Giancarlo Fatobene, MD, Hermes R Higashino, MD, Livia CM Compte, MD, Lucas BO Alves, PhD, Rogério Souza, MD.PhD, Silvia Costa, MD.PhD, Vanderson Geraldo Rocha, Full Professor, Vanderson Rocha, MD.PhD 2020-07-21
CLOVID-BH: Chemoprophylaxis with chloroquine in a high-risk population for the prevention of SARS-CoV-2 infections severity of infection Coronavirus disease 19 infection chloroquine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Centro de Pesquisas René Rachou, FIOCRUZ, Hospital das Clínicas UFMG FAPEMIG, Financiadora de Estudos e Projetos Brazil 2020-05-25 3.959.944 (nº parecer), 30287020.5.1001.5091 (CAEE), A14055253710, CLOVID-BH, RBR-7bxhrt Phase 3 Clinical Recruiting 1 1000 Israel Molina, Nínive da Silva Pinto 2020-07-22
Detection of COVID-19 Subjects Using DiaNose Exhalation Test Coronavirus disease 19 infection, Upper respiratory tract infection, Viral pneumonia DiaNose system alone, PCR test alone, breath test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Nanose Medical Ltd US, Israel 2020-08-01 2021-06-30 CORON01, NCT04476927 Phase Not Applicable Not yet recruiting 2 11 Months 300 Ravit Peled 2020-07-24
CIGB-2020 phase I/II clinical trial to assess safety and immunogenicity of different routes and modes of administration in older adults: Randomized, parallel-group clinical trial Coronavirus disease 19 infection CIGB-2020 alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Center for Genetic Engineering and Biotechnology Ministerio de Salud Publica Cuba 2020-07-29 2020-09-15 IG/VPNSL/IRA/2002, RPCEC00000326 Phase 1/Phase 2 Clinical Not yet recruiting 1 1 Month Alina Diaz Machado, Zurina Cinza Estevez 2020-07-21
PLEDGE: General Population Level Estimation for Type 1 Diabetes Risk in Children 0 to 5 Years Old During Routine Care Delivery Celiac disease, Coronavirus disease 19 infection, Insulin dependent diabetes blood sampling alone, differential gene expression alone Healthy volunteers accepted, Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs) Sanford Health Exeter University, Leona M and Harry B Helmsley Charitable Trust, Pacific Northwest Research Institute US 2020-07-17 2030-12-31 NCT04477928, PLEDGE, PLEDGE Phase Not Applicable Recruiting 1 125 Months 3000 Kurt Griffin, PhD, MD 2020-07-25
Evaluation of immunity in the evolution of the severe or mild form of COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Empresa Brasileira de Serviços Hospitalares, Fundacao Oswaldo Cruz (Fiocruz) Brazil 2020-06-12 30846920.7.0000.0008, 4.032.383, 4.077.252, RBR-62zdkk, U1111-1254-2547 Phase Not Applicable Recruiting 1 200 Ciro Martins Gomes, Licia Maria Mota, Patricia Shu Kurizky 2020-07-23
Risk Profiling of the Occupational Exposure of COVID-19 to Healthcare Workers Coronavirus disease 19 infection personal protective equipment usage alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) NMC Specialty Hospital United Arab Emirates 2020-08-01 2020-09-20 NCT04477213, NMCHCW-COVID Phase Not Applicable Not yet recruiting 2 1 Month 600 Helen King, RN DMS MBA, Prashant Nasa, Prashant Nasa, MD EDIC FNB, Surjaya Upadhyay, MD 2020-07-24
Development and Validation of 'Ready-to-Use' Inhalable Forms of Hydroxychloroquine for Treatment of COVID-19 Coronavirus disease 19 infection, Viral pneumonia hydroxychloroquine sulfate alone, oral antibiotic therapy alone, supportive and symptomatic treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mansoura University Egypt 2020-07-15 2020-08-15 INHALABLE HCQ, NCT04477083 Phase 2 Clinical No longer recruiting 1 1 Month 40 Ibrahim M. El-Sherbiny 2020-07-23
The Effect of D3 on Selected Cytokines Involved in Cytokine Storm in the Covid-19 Uninfected Jordanian People Coronavirus disease 19 infection, Vitamin D deficiency cholecalciferol alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Applied Science Private University Jordan 2020-08-05 2020-12-05 2020-PHA-16, NCT04476745 Phase Not Applicable Not yet recruiting 1 4 Months 100 Dana A Bader, MSc, Mahmoud S Abu-Samak, PhD 2020-07-22
Helmet-COVID: Helmet Non-Invasive Ventilation for COVID-19 Patients Coronavirus disease 19 infection, Hypoxia, Respiratory failure, Viral pneumonia Helmet alone, Helmet non-invasive ventilation alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) King Abdullah International Medical Research Center Saudi Arabia 2020-07-31 2022-01-31 Helmet-COVID, NCT04477668, RC20/306/R Phase Not Applicable Not yet recruiting 1 18 Months 320 Sheryl Ann Abdukahil, RN, Yaseen Arabi, MD 2020-07-22
A clinical trial comparing use of convalescent plasma therapy to standard therapy in patients with severe COVID-19 infection Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia Convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kenyatta University Kenya 2020-08-01 2021-12-31 PACTR202007653923168 Phase 2 Clinical Not yet recruiting 1 17 Months 206 Isaac Adembesa, Marion Kiguoya Njau, Samuel Akech 2020-07-29
Hyperbaric Oxygen as an Adjuvant Treatment for Patients With Covid-19 Severe Hypoxemia Coronavirus disease 19 infection, Hypoxia Revitalair 430 Hyperbaric Chamber alone, hyperbaric oxygen treatment alone, normobaric oxygen treatment alone, standard care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Asociación Argentina de Medicina Hiperbárica e Investigación Hospital Central De San Isidro, Argentina, Hospital Donation Francisco Santojanni, Hospital de Infecciosas Francisco Javier Muniz Argentina 2020-07-06 2020-12-30 AAMHEI2020-1, NCT04477954 Phase 2 Clinical Recruiting 3 5 Months 80 Cecilia Dominguez, MD, Eleonora Cunto, MD, Fabrizio Verdini, MD, Guillermo Keller, MD, Liliana Jorda-Vargas, Mariana Cannellotto, Mariana Cannellotto, MD, Mariano Duarte, PhD, Ramiro Larrea, MD, Viviana Chediack, MD 2020-07-24
SHIELD: Using Naso-oropharyngeal Antiseptic Decolonization to Reduce COVID-19 Viral Shedding Coronavirus disease 19 infection Standard personal protective equipment alone, chlorhexidine gluconate plus povidone-iodine Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Wisconsin-Madison US 2020-07-07 2021-04-30 2020-0540, A534265, NCT04478019, PROTOCOL VERSION 6/1/2020, SHIELD, SMPH/MEDICINE/INFECT DIS Phase 0 Clinical Recruiting 1 9 Months 94 Kendra Haight, RN BSN 2020-07-22
The effect of Hyoscyamus niger with propolis on COVID-19 Coronavirus disease 19 infection, Respiratory disease routine drug therapy alone, Hyoscyamus niger methanolic extract plus propolis Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Kashan University of Medical Sciences and Health Services Iran 2020-07-08 IR.KAMUS.REC.1399.016, IRCT20200516047462N2 Phase 2 Clinical Recruiting 3 90 Dr. Hamidreza Banafsheh, Mohammad Kazem Sayah, Morteza Kosari 2020-07-22
TOGETHER 3: TOGETHER 3 Trial. COVID-19 Coronavirus disease 19 infection, Lower respiratory tract infection lopinavir + ritonavir alone HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cytel Inc University of Washington South Africa 2020-07-13 20200410, PACTR202007700757139, TOGETHER 3 Phase 3 Clinical Not yet recruiting 1 420 Caroldine Neal, Eric Decloedt, Mark Cotton 2020-07-22
Management of the pulmonary diseases based on Persian medicine in patients infected with COVID-19 Coronavirus disease 19 infection, Respiratory tract infection Persian medicine diet alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Babol University of Medical Sciences Iran 2020-06-30 IR.MUBABOL.HRI.REC.1399.104, IRCT20200105046009N4 Phase 3 Clinical Recruiting 1 80 Reza Ghadimi, Seyyed Ali Mozaffarpur, SeyyedAli Mozaffarpur, Seyyedali Mozaffarpur 2020-07-22
Methodist Health System COVID-19 Patient Registry Coronavirus disease 19 infection Covid-19 treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Methodist Health System US 2020-08-31 2026-12-31 024.CRI.2020.A, NCT04477889 Phase Not Applicable Not yet recruiting 1 76 Months 500 Crystee Cooper, DHEd, Paola Gregoire, MS, MBA 2020-07-23
The effect of Pentoxifylline in patients with Covid-19 Coronavirus disease 19 infection, Dyspnea pentoxifylline, Farabi Pharmaceutical Company alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Karaj University of Medical Sciences Iran 2020-02-20 2020-07-05 IR.ABZUMS.REC.1399.102, IRCT20200705048013N1 Phase 3 Clinical Completed 1 4 Months 150 Davood Mohammadshahi, Dr. Mohammad Nouri-Sepehr, Sajjad Pourasghary 2020-07-22
The effect of Lactocare synbiotic on the prevention of COVID-19 infection in the staff of emergency department Coronavirus disease 19 infection Lactocare alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mashhad University of Medical Sciences Iran 2020-05-14 IR.MUMS.REC.1399.240, IRCT20101020004976N6 Phase 3 Clinical Recruiting 1 80 Dr Hamid Ahanchian, Hamid Ahanchian, ِDr. Mohsen Tafaghodi 2020-07-22
A clinical trial of VLA-2001 combined with an adjuvant CpG 1018 for potential treatment of COVID-19 infection Coronavirus disease 19 infection VLA-2001 alone Valneva SE Dynavax Technologies Corp Phase Not Applicable Planned 0 2020-07-21
Study in times of Corona protection measures. An online survey of medical students in the summer semester 2020 (COVID-19) Acute stress disorder, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Universitatsklinikum Essen Univeristat Duisburg-Essen Germany 2020-08-01 20-9370-BO, DRKS00022496, U1111-1255-6395 Phase Not Applicable Recruiting 2 1000 Dr. Eva Willmann, Martina Hessbruegge 2020-07-22
Ivermectin effect in the treatment of patients with covid-19 Coronavirus disease 19 infection antiviral drug therapy alone, hydroxychloroquine plus ivermectin, Erophartech Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Mashhad University of Medical Sciences Iran 2020-07-22 IR.MUMS.REC.1399.307, IRCT20190602043787N3 Phase 3 Clinical Recruiting 1 40 Dr Mohsen Tafaghodi, Saman Soleimanpour, Zahra Ataee 2020-07-22
Co-HCW: Survey of the seroprevalence and infection status of SARS-CoV-2 among employees of the University Hospital Jena (COVID-19) Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Jena University Hospital Germany 2020-05-19 2020-1774-1-Material, Co-HCW, DRKS00022432 Phase Not Applicable No longer recruiting 1 300 Ms. PD Dr. Christina Bahrs 2020-07-22
Co-NAN: Seroprevalence of SARS-CoV-2 antibodies in a quarantined community after a COVID-19 outbreak-the CoNAN study Coronavirus disease 19 infection Jena University Hospital Thüringer Ministerium für Wirtschaft, Wissenschaft und Digitale Gesellschaft Germany 2020-05-13 2020-1776_1-Material, Co-NAN, DRKS00022416 Phase Not Applicable No longer recruiting 1 800 Mathias Pletz, Studienambulanz Studienambulanz 2020-07-22
Vadadustat for the Prevention and Treatment of Acute Respiratory Distress Syndrome (ARDS) in Hospitalized Patients With Coronavirus Disease 2019 (COVID-19) Coronavirus disease 19 infection, Respiratory distress syndrome vadadustat alone HIF prolyl hydroxylase inhibitor, Hypoxia inducible factor inhibitor gene inhibitor, Hypoxia inducible factor-2 alpha modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Texas Health Science Center Houston Akebia Therapeutics Inc US 2020-08-01 2022-08-01 HSC-MS-20-0395, NCT04478071 Phase 2 Clinical Not yet recruiting 1 24 Months 300 Bentley J. Bobrow, MD 2020-07-22
European Pathology Laboratories and COVID-19 Coronavirus disease 19 infection Centre Hospitalier Universitaire De Nice France 2020-03-15 2020-05-31 20LABOCOVID01, NCT04476823 Phase Not Applicable Completed 1 2 Months 71 2020-07-22
RAPTOR-C19: Rapid community testing for COVID-19 Coronavirus disease 19 infection point-of-care diagnostic tests or near-patient tests alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Oxford Medical Research Council, United Kingdom Research & Innovation UK 2020-04-01 2022-06-03 CPMS 46023, IRAS 284320, ISRCTN14226970, RAPTOR-C19 Phase Not Applicable Recruiting 2 26 Months 2000 Dr Brian Nicolson, Ms Logan 2020-07-24
MELCOVID: Phase II, clinical trial, single-blind, randomized, placebo-controlled to explore the effectiveness and safety of melatonin in patients with COVID-19 entered into the intensive care unit Coronavirus disease 19 infection, Respiratory failure melatonin alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Pharmamel S.L. Spain 2020-06-17 2020-001808-42, MELCOVID, PHM-2020-001 Phase 2 Clinical Recruiting 1 18 Catedrática de Fisiología 2020-07-22
Clinical features and prognostic factors for patients admitted for COVID-19 pneumonia Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Azienda Sanitaria n. 4 Chiavarese, General hospital of sestri levante Italy, Spain 2020-03-15 2020-05-25 ChiCTR2000034798 Phase 0 Clinical No longer recruiting 2 2 Months 309 Nicolini Antonello 2020-07-22
POSEIDON-CRISIS: Trajectories of stress and mental health in children and their parents during a health crisis (COVID-19) in a longitudinal birth cohort study Acute stress disorder, Coronavirus disease 19 infection Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Institute of Mental Health, Mannheim Germany 2020-06-29 DRKS00003600 (Hauptstudie), DRKS00022180, POSEIDON-CRISIS Phase Not Applicable Not yet recruiting 1 400 Ms. PD Dr. Stephanie Witt, Ms. Thao Nguyen 2020-07-22
Diabetes Mellitus (DM) Movement Control Order (MCO) Coronavirus disease 19 infection, Non-insulin dependent diabetes Taiping Hospital Malaysia 2020-08-15 2020-12-31 55499, NMRR-20-1515-55499 Phase Not Applicable Status not specified 1 4 Months Dr Narwani Hussin, M.SREEVALI A/P V MUTHUVADIVELU 2020-07-24
To study the effect of BCG vaccine in Reducing the Incidence and severity of COVID-19 in the high-risk population Coronavirus disease 19 infection Bacillus Calmette-Guerin (BCG) vaccine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Indian Council of Medical Research India 2020-08-05 CTRI/2020/07/026668 Phase 3 Clinical Not yet recruiting 3 800 Dr Sanjeev Sinha 2020-07-23
BCG Vaccine in Reducing Morbidity and Mortality in Elderly Individuals in COVID-19 Hotspots Coronavirus disease 19 infection, Respiratory disease BCG vaccine (Freeze-dried), Serum Institute of India alone Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tuberculosis Research Centre All India Institute of Medical Sciences, King Edward Memorial Hospital, National Institute for Research in Environmental Health, Bhopal, Madhya Pradesh, National Institute of Occupational Health, Ahmedabad, Gujarat India 2020-07-01 2021-05-31 2020010, NCT04475302 Phase 3 Clinical Recruiting 1 11 Months 2175 Anant Mohan, Asha Keetharam, Hemant Deshmukh, Kamalesh Sarkar, Padmapriyadarsini Chandrasekaran, MBBS,DNB,MS, Randeep Guleria, Rujuta Hadaye, Subash Babu, MBBS, PhD, Tiwari R R., Toteja G.S., Yogesh Sabde 2020-07-27
Unani Herbal tablets for mild cases of Covid-19 Coronavirus disease 19 infection Variable regimens including Aloe Vera gel (Aloe barbadenesis) , Mur Makki (Commiphora myrrha) , Sanna-e-Makki (Senna Alexandrina)  Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Z V M Unani Medical College & Hospital India 2020-08-03 CTRI/2020/07/026669 Phase Not Applicable Not yet recruiting 1 60 Dr Ghazala Mulla, Dr Jalis Ahmed, Dr Shaikh Nikhat 2020-07-23
The Efficacy and Safety of Pyramax in Mild-to-Moderate COVID-19 Patients Coronavirus disease 19 infection pyronaridine + artesunate (oral), Medicines for Malaria Venture/Shin Poong/WHO alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shin Poong Pharmaceutical Co Ltd South Korea 2020-07-31 2021-02-28 NCT04475107, SP-PA-COV-201 Phase 2 Clinical Recruiting 8 7 Months 76 Kim 2020-07-30
Role of immune boosting kit in covid disease Coronavirus disease 19 infection Variable regimens including anu taila , chyawanprash , chyawanprash avaleha , sanshamani vati Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) All India Institute of Ayurveda India 2020-07-28 CTRI/2020/07/026670 Phase Not Applicable Not yet recruiting 1 500 Dr SISIR KUMAR MANDAL 2020-07-22
What are the clinical effects in newborns born to mothers exposed to COVID-19 viral infection Coronavirus disease 19 infection Newborn Infants (up to 5 months) Chengalpattu Medical College India 2020-07-30 CTRI/2020/07/026678 Phase Not Applicable Not yet recruiting 1 200 Dr M Anitha 2020-07-22
Use of a Live Attenuated Vaccine as an Immune-based Preventive Against COVID-19-associated Sepsis Coronavirus disease 19 infection, Lung inflammation, Sepsis M-M-R II alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Louisiana State University Health Sciences Center New Orleans Parsemus Foundation US 2020-08-17 2021-12-01 NCT04475081, PF-1214 Phase 3 Clinical Not yet recruiting 1 15 Months 60 Mary Meyaski, RN, Paul L Fidel, PhD 2020-07-22
Efficacy of Ayurveda treatment Protocol with Tulsimmune Tablet in Covid 19 Coronavirus disease 19 infection Ayurveda spice mix tablet (Tulsimmune) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Suraj Ayurveda Clinic and Research center H.J. Doshi Ghatkopar Hindusabha Hospital India 2020-07-27 CTRI/2020/07/026675 Phase 1/Phase 2 Clinical Not yet recruiting 1 76 Dr Akshaya Wagh Dr Pratika Kambale, Dr Ghanashyam Marda 2020-07-22
Ozone Therapy for Covid-19 patients Coronavirus disease 19 infection ozone therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Neurogen Brain and Spine Institute Bisleri International Pvt. Ltd. India 2020-07-27 CTRI/2020/07/026671 Phase Not Applicable Not yet recruiting 1 10 Dr Alok Sharma, Dr Mili Arpan Shah 2020-07-30
Mental health affected by COVID-19 Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Tata Memorial Hospital India 2020-07-28 CTRI/2020/07/026672 Phase Not Applicable Not yet recruiting 1 2000 Arjun Singh, Pankaj Chaturvedi 2020-07-22
Effect of Ayurveda Spice Mix Tablet for the Prevention of COVID-19 infection in people exposed to Covid 19 and in high risk patients Coronavirus disease 19 infection Ayurveda Spice Mix alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Suraj Bio Herbal Pvt ltd Ashtang Ayurveda Mahavidyalaya India 2020-07-27 CTRI/2020/07/026674 Phase 1 Clinical Not yet recruiting 1 130 Dr Ghanashyam Marda, Dr Manoj Chaudhari 2020-07-22
SARS CoV2 pneumonia NIVS: Management of acute respiratory failure due to SARS CoV2 with non-invasive ventilatory support Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Azienda Sanitaria n. 4 Chiavarese, General hospital of sestri levante Spain, Italy 2020-03-15 2020-05-25 ChiCTR2000034784, SARS CoV2 pneumonia NIVS Phase 4 Clinical Completed 2 2 Months 104 Nicolini Antonello, Russo Giuseppe 2020-07-21
Siddha formulations for the prevention of COVID-19 infection Coronavirus disease 19 infection Siddha formulation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Ministry of Ayush India 2020-08-05 CTRI/2020/07/026673 Phase 2/Phase 3 Clinical Not yet recruiting 1 60 Dr C Savariraj Sahayam, Dr G Karthikayan MBBS MS 2020-07-22
Can the Electronic Nose Smell COVID-19 Antibodies? Coronavirus disease 19 infection Aeonose alone, breath test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Maastricht University Medical Center Netherlands 2020-04-06 2020-07-01 ENOSECOVIDANTIBODIES, NCT04475575 Phase Not Applicable Completed 1 2 Months 222 Nicole Bouvy 2020-07-21
A follow-up study of long-term prognosis in patients with severe novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Wuhan Jinyintan Hospital China 2020-05-30 2021-05-30 ChiCTR2000034781 Phase Not Applicable Recruiting 1 12 Months 280 Huang ChaoLin, LIU YING, Shang You, Zhou Xi 2020-07-23
CRAFTftiugr: The Effects of Mindfulness-based Training in Undergraduate Students of Translation and Interpreting Acute stress disorder, Anxiety disorder, Cognitive disorder, Coronavirus disease 19 infection The CRAFT program (adapted due to COVID-19) alone, The MBSR program (adapted due to COVID-19) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Granada Spain 2019-10-23 2020-10-31 CRAFTftiugr, NCT04392869, PIBPD 431 (PPFID 2018-2020) Phase Not Applicable No longer recruiting 1 12 Months 75 2020-07-21
A real-time trial to evaluate the technology to screen Coronavirus disease 19 infection Coronavirus disease 19 infection advanced algorithms alone, artificial intelligence alone, thermal and visible-light cameras alone Foresight Autonomous Holdings Ltd Israel Phase Not Applicable Status not specified 1 2020-07-27
Uberisation, Peritoneal Dialysis, COVID-19 Coronavirus disease 19 infection, Renal disease Home CAPD Training Program alone, Peritoneal Dialysis alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ministry of Health, Malaysia, National Institutes of Health Malaysia Malaysia 2020-08-03 2021-01-29 55623, NMRR-20-1514-55623 Phase Not Applicable Not yet recruiting 1 5 Months ANG KIM LIONG, Dr Goh Bak Leong 2020-07-24
A Phase III, clinical trial for inactivated novel coronavirus pneumonia (COVID-19) vaccine (Vero cells) Coronavirus disease 19 infection inactivated SARS-COV2 vaccine (Vero cells), China National Biotec Group alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Beijing Biological Products Institute Co Ltd, China National Biotec Group, Sheikh Khalifa Medical City, Wuhan Institute of Biological Products Co Ltd Ministry of Science and Technology of the People´s Republic of China China 2020-07-16 2021-07-15 ChiCTR2000034780 Phase 3 Clinical Recruiting 1 12 Months 15000 Abu Dhabi, Wei Chen 2020-07-23
Review of pharmacotherapy outcomes for hospitalized COVID-19 patients in Malaysia Coronavirus disease 19 infection, Cough, Dyspnea, Fever pharmacotherapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Kuala Lumpur Malaysia 2020-07-17 2021-07-15 55689, NMRR-20-1511-55689 Phase Not Applicable Status not specified 1 11 Months 250 Mrs merina aw kar ling 2020-07-22
PSICOcs: Online Survey on Psychological Impact of COVID-19 Epidemic on School-age Children Coronavirus disease 19 infection, Psychiatric disorder Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Hospices Civils De Lyon France 2020-06-10 2020-12-31 NCT04475484, PSICOCS_2020, PSICOcs Phase Not Applicable Recruiting 1 6 Months 30000 Pauline Espi, Pierre Fourneret, Pierre Pierre Fourneret 2020-07-21
Postural Recruitment Maneuver in Patients With Acute Respiratory Distress Syndrome Due to COVID-19 Infection Coronavirus disease 19 infection, Respiratory distress syndrome opioids therapy alone, postural recruitment maneuver alone, sedatives therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Nacional Edgardo Rebagliati Martins University of Piura Peru 2020-07-31 2020-10-31 HNEDGARDOREBAGLIATIMARTINS, NCT04475068 Phase Not Applicable Not yet recruiting 1 3 Months 12 Jorge A García, MD, Rollin Roldán, MD 2020-07-21
A clincial trial of immunotherapy (COVID19 infection),Fabentech for the potential treatment against COVID-19 Coronavirus disease 19 infection immunotherapy (COVID19 infection), Fabentech alone Fabentech Phase Not Applicable Planned 0 2020-07-23
Efficacy of Pranayama on Positivity rate in People exposed to Covid-19 Patients and mental status Coronavirus disease 19 infection pranayama (yoga) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ministry of Ayush India 2020-07-17 CTRI/2020/07/026667 Phase Not Applicable Not yet recruiting 1 250 Ishwarappa V Basavaraddi 2020-07-23
Experience Repatriation Of Citizens From Epicenter Using Commercial Flights During Covid-19 Pandemic Coronavirus disease 19 infection Hospital Sungai Buloh Malaysia 2020-02-03 2020-07-01 55829, NMRR-20-1508-55829 Phase Not Applicable Status not specified 1 4 Months Dr Sarah Binti Shaikh Abdul Karim 2020-07-22
Hypercoag. Covid-19 And Management Coronavirus disease 19 infection Anticoagulation alone Hospital Tuanku Fauziah Malaysia 2020-08-03 2021-07-31 55818, NMRR-20-1507-55818 Phase Not Applicable Status not specified 1 11 Months NURUL NAJMEE BINTI ABDUL KADIR 2020-07-22
COVID-19; a report of three asymptomatic cases in a HEI in Sabah Coronavirus disease 19 infection Universiti Malaysia Sabah Malaysia 2020-07-16 2020-08-07 55691, NMRR-20-1502-55691 Phase Not Applicable Status not specified 1 Dr Syaza Putri Binti Zainudin 2020-07-21
Association between knowledge and practice of patients in KK Senawang during Covid-19 pandemic Coronavirus disease 19 infection Klinik Kesihatan Senawang Malaysia 2020-07-16 2020-12-31 55459, NMRR-20-1505-55459 Phase Not Applicable Status not specified 1 5 Months Leviniya A/P Gunaselan Thangaraj 2020-07-22
QValidationKAPCOVID19: QValidationKAPCOVID19 Coronavirus disease 19 infection Hospital Tuanku Fauziah Malaysia 2020-07-27 2021-07-27 55743, NMRR-20-1501-55743, QValidationKAPCOVID19 Phase Not Applicable Status not specified 2 12 Months DR AMALINA BINTI ANUAR 2020-07-30
Co-Ab Study: COVID-19 Antibody Response Coronavirus disease 19 infection RT-PCR alone Hospital Sungai Buloh Malaysia 2020-08-01 2021-08-01 Co-Ab Study, NMRR-20-1498-55694 Phase Not Applicable Not yet recruiting 1 12 Months 250 Dr LIM KAH CHUAN, Dr Syarifah Nurul Ain Bt Syed Badaruddin 2020-07-21
Efficacy and Safety of Liposomal Lactoferrin in COVID-19 Patients With Mild-to-Moderate Disease and in COVID-19 Asymptomatic Patients Coronavirus disease 19 infection liposomal lactoferrin alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Rome Tor Vergata Italy 2020-04-15 2020-07-02 4220, NCT04475120 Phase 2/Phase 3 Clinical Completed 1 2 Months 60 Elena Campione, Associate Professor 2020-07-21
Ordinary Clinical Waste Management and Covid-19 Clinical Waste Coronavirus disease 19 infection Universiti Malaysia Sabah Malaysia 2020-07-20 2020-08-31 NMRR-20-1495-55515 Phase Not Applicable Status not specified 1 1 Month Ms. Nurul Izzatul Fasihah Binti Roman Hatar 2020-07-21
Nurses' Preparedness and Readiness in Managing A Disaster During COVID-19 Coronavirus disease 19 infection Universiti Malaysia Sabah Malaysia 2020-08-03 2021-07-30 55626, NMRR-20-1494-55626 Phase Not Applicable Status not specified 4 11 Months Chua Bee Seok 2020-07-22
Stay Well at Home: a Text-messaging Study Social Distancing Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression Reinforcement learning message delivery alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of California at Berkeley US 2020-04-17 2021-04-01 2020-04-13162, NCT04473599 Phase Not Applicable Recruiting 2 11 Months 200 Adrian Aguilera, PhD, Caroline Figueroa, MD PhD, Rosa Hernandez-Ramos, Bsc 2020-07-29
The efficacy and safety of heparin in the treatment of novel coronavirus pneumonia (COVID-19): a prospective, randomized, controlled trial Coronavirus disease 19 infection, Viral pneumonia heparin alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rui Jin Hospital Science and Technology Commission of Shanghai Municipality China 2020-01-20 ChiCTR2000034796 Phase 0 Clinical Recruiting 1 Enqiang Mao, Ma Li 2020-07-22
Safety and Efficacy of Maraviroc and/or Favipiravir versus Standard Therapy in Severe COVID-19 Adults Coronavirus disease 19 infection standard therapy alone, Variable regimens including azithromycin , chloroquine , enoxaparin sodium , favipiravir , hydroxychloroquine , maraviroc CCR5 chemokine antagonist, CD4 agonist, HIV-1 gp120 protein inhibitor, Low molecular weight heparin, RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hospital General de Mexico CCINSHAE. Secretaría de Salud. México, Centro de Investigación en. Enfermedades Infecciosas, Instituto Nacional de Ciencias Medicas y Nutricion Mexico 2020-07-31 2021-01-31 DI/20/407/04/38, NCT04475991 Phase 2 Clinical Not yet recruiting 1 6 Months 100 Adolfo Pérez-García, PhD, Joselin Hernández-Ruiz, PhD, María Luisa Hernández-Medel, MD 2020-07-27
RESTORE: Reducing Burnout Among Frontline Healthcare Workers During COVID-19 Acute stress disorder, Coronavirus disease 19 infection, Depression Virtual Peer Support Platform alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) St Josephs Healthcare Hamilton Canada 2020-07-31 2021-07-31 11136, NCT04474080, RESTORE Phase Not Applicable Not yet recruiting 1 12 Months 1080 Jacqueline Hudson, Zainab Samaan, MBChB, PhD 2020-07-21
COVRESP: Safety and Effectiveness Assessment of the MakAir Artificial Ventilator Coronavirus disease 19 infection, Respiratory distress syndrome MakAir artificial ventilator alone, Mechanical ventilation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) CHU De Nantes France 2020-07-31 2020-10-31 COVRESP, NCT04475185, RC20_0173 Phase Not Applicable Recruiting 2 3 Months 117 Antoine Roquilly, MD, Erwan L'Her, MD 2020-07-23
The therapeutic efficacy of Xuan-Fei Bai-Du decoction in the treatment of novel coronavirus pneumonia (COVID-19): a pilot randomized controlled trial Coronavirus disease 19 infection, Viral pneumonia Xuanfei Baidu Decoction alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Wuhan Hospital of Traditional Chinese Medicine China 2020-01-28 2020-02-29 ChiCTR2000034795, ChiMCTR2000003500 Phase 0 Clinical No longer recruiting 1 1 Month 42 Wu-zhong Xiong 2020-07-21
Digital versus Analog Impression in Cases of All-on-4 - Prosthesis Bone resorption, Coronavirus disease 19 infection DIG Axial implant alone, DIG Tilted implant alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) October University for Modern Sciences and Arts Egypt 2018-07-11 2020-08-31 5, NCT04475913 Phase Not Applicable No longer recruiting 1 25 Months 56 Dina Elawady 2020-07-21
Sancai granule improves lung and kidney function for patient with novel coronavirus pneumonia (COVID-19) in the recovery period: a randomized, parallel controlled trial Coronavirus disease 19 infection, Renal disease, Respiratory disorder, Viral pneumonia Sancai Granule alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hubei province hospital of Traditional Chinese Medicine China 2020-05-01 2021-04-30 ChiCTR2000034794, ChiMCTR2000003499 Phase Not Applicable Recruiting 1 12 Months 60 Ba Yuanming, Shen Yinfeng 2020-07-21
Can the Electronic Nose Smell COVID-19? Coronavirus disease 19 infection Aeonose electronic nose alone, breath analysis alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Maastricht University Medical Center Netherlands 2020-04-06 2020-07-01 ENOSECOVID, NCT04475562 Phase Not Applicable Completed 1 2 Months 219 Nicole Bouvy 2020-07-22
Telerehabilitation After Coronavirus Coronavirus disease 19 infection Aerobic Exercise Training alone, Respiratory Exercise Training alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) KTO Karatay University Turkey 2020-06-19 2020-12-19 KARATAYU2, NCT04473898 Phase Not Applicable Recruiting 1 6 Months 36 Bayram Sönmez Ünüvar, MsC, PT, Buse Kılınç, PT, Büşra Alkan, MsC, PT, RA, Büşra Alkan, MsC, PT,RA, Hasan Gerçek, PT, Kamil Yılmaz, Phd, PT, Melike Akdam, PT, RA, Osman Karaca, MsC,PT, Sinan Bağçacı, Dr, Özlem Akkoyun Sert, Phd, PT 2020-07-28
COVIDENZA: Enzalutamide Treatment in COVID-19 Coronavirus disease 19 infection enzalutamide alone, standard of care alone Androgen receptor antagonist, Cytochrome P450 3A4 stimulator, DNA binding protein inhibitor, Prostate specific antigen modulator, Translocation associated protein inhibitor Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Västerbotten County Council, Sweden Astellas Pharma Europe Ltd, Göteborg University, Helsingborgs Hospital, Norrlands Universitetssjukhus, Sahlgrenska University Hospital, Skåne University Hospital, Sundsvall Hospital, Umea University, Umeå University Hospital, Uppsala University Sweden 2020-07-15 2022-05-08 COVIDENZA, COVIDENZA, NCT04475601 Phase 2 Clinical Recruiting 2 21 Months 500 Anders Bjartell, Anders Bjartell, MD/Prof, Andreas Josefsson, Andreas Josefsson, MDPhD, Andreas Josefsson, MdPhD, Anna Henningsson Jonsson, MDPhD, Anna Nilsson, David Robinsson, MDPhD, Karin Welén, Assoc. Professor 2020-07-30
World Heart Federation (WHF) COVID-19 and Cardiovascular Disease Survey Cardiovascular disease, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Public Health Foundation of India Centre for Chronic Disease Control, University of Cape Town, World Heart Federation, Geneva, Switzerland Ghana, Iran, India, Argentina, Bosnia and Herzegovina, Sudan 2020-06-11 2021-12-30 NCT04475471, RA1413 Phase Not Applicable Recruiting 8 18 Months 5200 Ahmed Suliman, Alejo P. de la Hoz, Bishav Mohan, Bojan Stanetiic, DORAIRAJ PRABHAKARAN, MD, DM, Dorairaj Prabhakaran, Ezequiel J. Zaidel, Jose M. Aladio, KAREN SILWA, MD, PhD, KAVITA SINGH, PhD, Ladan Sadeghian, Lambert T. Appiah, Maia Matsudo, Nizal Sarrafzadegan, Pablo PEREL, MD, PhD, Ricardo P. de la Hoz, Sandra Swieszkowski, Sayed M. Hashemi 2020-07-21
A trial to evaluate opaganib for the treatment of patients with severe COVID-19 infection and pneumonia Coronavirus disease 19 infection, Viral pneumonia opaganib alone Dihydroceramide delta 4 desaturase inhibitor, Sphingosine kinase 2 inhibitor RedHill Biopharma Ltd Israel Phase 2 Clinical Not yet recruiting 1 50 2020-07-20
LICORNE: Lille COVID Research Network (Covid-19) Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Regional Universitaire de Lille France 2020-07-31 2022-07-31 2020-A01514-35, 2020_54, LICORNE, NCT04475211 Phase Not Applicable Not yet recruiting 1 24 Months 1000 Marie-Charlotte CHOPIN, MD 2020-07-21
RAnPallCo: Mental recilience in relatives of inpatient palliative care patients during the Corona pandemic (COVID-19) Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Psychiatric disorder DynaCORE-C questionnaire alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mainz University Hospital Germany 2020-07-17 2020-15142, DRKS00022463, RAnPallCo Phase Not Applicable Recruiting 2 100 Sandra Stephanie Mai 2020-07-22
Study by DB Fernverkehr AG on corona infections and corona immunity of its employees (COVID-19) Coronavirus disease 19 infection IgG-antibody-test alone, PCR-test alone DB Fernverkehr AG Charite Universitaetsmedizin Berlin Germany 2020-06-29 DRKS00022359, Eth.19/20 Phase Not Applicable Recruiting 4 1050 Christian Gravert 2020-07-22
Clinical pilot study on the effects of a hydrogen peroxide mouthrinse on the intraoral viral load of SARS-CoV-2 (COVID-19) Coronavirus disease 19 infection hydrogen peroxide alone University of Regensburg Germany 2020-04-09 20-1787-101, DRKS00022484 Phase 2 Clinical Recruiting 1 50 Fabian Cieplik 2020-07-23
Trial comparing different doses of single-dose tocilizumab in adults with severe COVID-19 infection Coronavirus disease 19 infection tocilizumab (intravenous), Roche/Chugai alone IL-6 receptor antagonist, IL-6 receptor modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University College Dublin Ireland 2020-06-25 2020-001767-86, COVIRL-002 Phase 2 Clinical Recruiting 1 90 QRAM 2020-07-21
RECOVER-19: Functional and Respiratory Rehabilitation and Nutritional Care of COVID Patients Coronavirus disease 19 infection, Malnutrition Regular physical activity alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rennes University Hospital France 2020-07-13 2021-08-13 35RC20_9875_RECOVER-19, NCT04466800, RECOVER-19 Phase Not Applicable Not yet recruiting 3 13 Months 160 Aranzazu PEDROSA GONZALEZ, Dr, Christophe POPINEAU, Dr, Lilian Alix, Dr 2020-07-24
WHO-SOLIDARITY-GERMANY: An international randomized trial of additional treatments for COVID-19 in hospitalized patients who are all receiving the local standard of care Coronavirus disease 19 infection Variable regimens including interferon beta-1a , lopinavir + ritonavir , remdesivir COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, HIV protease inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Landeszentrum Gesundheit Nordrhein-Westfalen German Federal Ministry of Education and Research Germany 2020-06-29 2020-001549-38, WHO-SOLIDARITY-GERMANY, WHO-SOLIDARITY-GERMANY Phase 3 Clinical Recruiting 1 800 Institut für Pharmakologie 2020-07-23
[68Ga]Ga-DOTA-(RGD)2 PET/CT imaging of activated endothelium in lung parenchyma of COVID-19 patients Coronavirus disease 19 infection [68Ga]Ga-DOTA-E-(cRGDfK)2 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Radboud University Medical Center Nijmegen Netherlands 2020-05-20 2020-001325-31, NL73551.091.20 Phase 2 Clinical Recruiting 1 10 Nuclear Medicine Research Office 2020-07-21
BADS-PTSD: Assessment of Mental Health in Healthcare Workers Exposed to COVID-19 Patients Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hamad Medical Corp Qatar 2020-07-11 2021-06-30 BADS-PTSD, MRC-05-017, NCT04473118 Phase Not Applicable Recruiting 1 11 Months 25000 Ali Ait Hssain, Dr. Ali Ait Hssain, Sara Taleb 2020-07-20
ASAP: Ambulance Calls for Substance Use and Alcohol in a Pandemic Alcoholism, Coronavirus disease 19 infection, Drug dependence attendance by ambulance crew alone Healthy volunteers accepted University of Lincoln UK 2019-03-23 2021-03-23 ASAP, ASAP01, NCT04474444 Phase Not Applicable Recruiting 1 24 Months 55000 Graham Law, PhD, Sam Lewis 2020-07-22
QUICK: Lung Ultrasound for COVID-19 Initial Triage and Monitoring Coronavirus disease 19 infection computed tomography alone, thoracic lung ultrasound alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire de Toulouse France 2020-05-27 2021-03-27 2020-A01445-34, NCT04474236, QUICK, RC31/20/0182 Phase Not Applicable Recruiting 1 10 Months 148 Benjamine SARTON, ph 2020-07-20
Ayurvedic formulations for the prevention of COVID-19 infection Coronavirus disease 19 infection Ayurvedic formulations alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Sastra University India 2020-08-01 CTRI/2020/07/026530 Phase 2/Phase 3 Clinical Not yet recruiting 1 200 Dr A Vinoth, Dr S Manickasubramaniam, Dr S Swaminathan 2020-07-21
Double-blind, randomized, controlled clinical trial to assess the efficacy of allogenic mesenchymal stromal cells in patients with acute respiratory distress syndrome due to COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome allogenic mesenchymal stromal cells alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cristina Avendaño Sola Hospital Puerta de Hierro Majadahonda Spain 2020-06-15 2020-002193-27, COVID-AT Phase 2 Clinical Recruiting 1 20 Concepcion Payares-Herrera 2020-07-20
ROLL OVER COVID: A Study of Lying Face Down to Help Improve Oxygen Levels of Adults Not Needing Ventilators in Intensive Care with COVID-19 Coronavirus disease 19 infection early prone positioning alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Royal Prince Alfred Hospital Australia 2020-07-16 ACTRN12620000740998, ROLL OVER COVID Phase Not Applicable Not yet recruiting 1 20 Dr Thomas Melhuish 2020-07-21
An Epidemiological Investigation on the Correct Wearing of Face Mask Coronavirus disease 19 infection, Respiratory tract infection FT-30 qualitative fitness test system (3M company) alone, Face mask wearing alone, breathing test alone, fitness test reagent spray test alone, hood wearing alone, sensitivity test alone, suitability test reagent spray test alone, visual inspection alone Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cardiovascular Institute and Fuwai Hospital China 2020-06-19 2020-08-31 2020-KZLXB-01, NCT04474028 Phase Not Applicable Recruiting 8 2 Months 5000 Bin Wen, Lin Duo, Pengxu Kong, Rundi Deng, Xiang-Bin Pan 2020-07-22
SENTAD-COVID: Study Evaluating the Safety and Efficacy of Autologous Non-Hematopoietic Peripheral Blood Stem Cells in COVID-19 Coronavirus disease 19 infection COVID-19 standard care alone, autologous non-hematopoietic peripheral blood stem cells alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Abu Dhabi Stem Cells Center United Arab Emirates 2020-04-04 2020-07-14 CT.001.1.0.SENTAD-COVID, NCT04473170, SENTAD-COVID Phase 1/Phase 2 Clinical Completed 1 3 Months 146 Yendry Ventura Carmenate, M.D. 2020-07-20
Impact of COVID-19 on Marshallese Communities in the U.S Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Arkansas Patient Centered Outcome Research Institute US 2020-07-20 2020-11-01 261131, NCT04474496 Phase Not Applicable Not yet recruiting 1 3 Months 2000 Ralph Wilmoth, MPH, MPA 2020-07-20
Well-Being and Health-Related Quality of Life in Melanoma Patients During COVID-19 Pandemic Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression, Melanoma MD Anderson Cancer Center National Cancer Institute US 2020-06-11 2021-07-01 2020-0470, NCI-2020-04587, NCT04474301, P30CA016672 Phase Not Applicable Recruiting 1 12 Months 1152 Lorenzo Cohen 2020-07-20
Optimizing Resource Allocation Via Prediction of Outcomes for COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Nottingham University Hospital East Midlands Academic Health Science Network UK 2020-05-01 2020-07-31 20GA039, NCT04473105 Phase Not Applicable Recruiting 1 3 Months 500 Colin Crooks, MRCP, PhD, Timothy R Card, FRCP, PhD 2020-07-20
Epidemiological Assessment of SARS-CoV-2 (COVID-19) Prevalence in Minnesota Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Minnesota US 2020-07-31 2022-01-31 NCT04473183, SURG-2020-28863 Phase Not Applicable Not yet recruiting 1 18 Months 3000 Luca Schifanella, MD, PhD 2020-07-20
IMPROVISE: Immune Profiling of COVID-19 patients Admitted to ICU Coronavirus disease 19 infection immune proteomics analysis alone, metabolomics analysis alone, serological test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hamad Medical Corp Qatar University, Weill Cornell Medical College in Qatar Qatar 2020-04-27 2022-06-30 IMPROVISE, MRC-05-007, NCT04473131 Phase Not Applicable Recruiting 1 26 Months 300 Ali Ait Hssain, Dr. Ali Ait Hssain, Sara Taleb 2020-07-20
Efficacy and Safety of Favipiravir in the Treatment of COVID-19 Patients > 15 Years of Age Coronavirus disease 19 infection favipiravir alone RNA polymerase inhibitor Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ministry of Health of Turkey Ankara City Hospital Bilkent, Ankara Training and Research Hospital, Ankara University, Ege University Hospital (Application and Research Center), Hacettepe University, Hacettepe University, School of Medicine, Istanbul Training and Research Hospital, Istanbul University, Istanbul University-Cerrahpasa, Kayseri City Hospital, Kocaeli Derince Training and Research Hospital, Prof. Dr. Cemil Tascıoglu City Hospital, Tepecik Training and Research Hospital, gulhane military medical academy, Ümraniye Training & Research Hospital Turkey 2020-06-11 2020-09-30 COVID-19-PMS-FAV, NCT04474457 Phase Not Applicable Recruiting 1 3 Months 1000 Prof. Ates KARA, MD, Prof. Ateş KARA, MD 2020-07-22
COVID-19 Vaccine Trial in Healthy Volunteers Coronavirus disease 19 infection SARS-CoV-2 subunit vaccine (tobacco plant technology, COVID-19), Kentucky BioProcessing alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Kentucky BioProcessing Inc 2020-07-31 2021-11-23 KBP-201, NCT04473690 Phase 1/Phase 2 Clinical Not yet recruiting 0 15 Months 180 Dennis Ruff, MD, Hugh Haydon, Kevin Cannon, MD, Oscar Guzman 2020-07-29
FUP-COVID: Follow-up of Critical COVID-19 Patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Uppsala University Sweden 2020-06-25 2022-12-31 EPM-2020-02697, FUP-COVID, NCT04474249 Phase Not Applicable Recruiting 1 30 Months 300 Ewa Wallin, PhD., Ing-Marie Larsson, PhD., Michael Hultström, MD. PhD., Miklos Lipcsey, MD. PhD., Robert Frithiof, MD. PhD., Sten Rubertsson, MD. PhD. 2020-07-21
COVID-19 Convalescent Plasma Treatment in SARS-CoV-2 Infected Patients Coronavirus disease 19 infection, Viral pneumonia COVID-19 convalescent plasma alone, hospital guideline based premedication therapy alone, steriod therapy alone, Variable regimens including COVID-19 convalescent plasma , acetaminophen , diphenhydramine Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ministry of Health in Kuwait Kuwait 2020-05-21 2020-12-30 MOHKUWAIT, NCT04474340 Phase 1 Clinical Recruiting 1 7 Months 300 Abdullah Alsaedi, MD, Fatmah Alhuraish, MD, Mariam Ayed, Md, Najat Rouhaldeen, MD, Reem Ameen, PhD, Salem Alqahtani, MD, Sondus AlSharida, MD, Sondus AlSharidah, Sondus AlSharidah, MD, Sundos Alsharida, Wasel Aladsani, MD 2020-07-23
Assessment of Lung Recruitablity of Acute Respiratory Distress Syndrome With SARS-CoV-2 Pneumonia by Electrical Impedance Tomography Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia electrical impedance tomography alone, opioid therapy alone, rocuronium alone, sedative therapy alone, ventilation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Osaka City University Hospital Edgardo Rebagliati Martins Japan 2020-05-11 2020-08-31 ASPEIT, NCT04473300 Phase 2 Clinical Recruiting 1 3 Months 20 Takeshi Yoshida, M.D., Ph.D., Takeshi Yoshida, PhD 2020-07-20
A Study to evaluate the safety and efficacy of Eflornithine against the standard of care in human adult hospitalized COVID-19 patients Coronavirus disease 19 infection eflornithine alone Ornithine decarboxylase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) SRV Hospital India 2020-07-20 CTRI/2020/07/026529 Phase 2/Phase 3 Clinical Not yet recruiting 1 18 Dr Abhay Vispute Shantaram 2020-07-20
COVID-19 Preventive Measures Among Mansoura Nursing Students Coronavirus disease 19 infection Mansoura University Egypt 2020-07-15 2020-12-31 NCT04473547, P.0203 Phase Not Applicable Recruiting 1 5 Months 215 Mohamed elsayed hamed elzeky, Wafaa G mohamed ali, professor, mohamed E elzeky, lecturer, mohamed elsayed elzeky, lecturer 2020-07-20
A clinical study to evaluate the efficacy of Arakoda for the potential treatment of COVID-19 Coronavirus disease 19 infection tafenoquine (oral tablet, malaria), 60° Pharmaceuticals/United States Army/Biocelect alone 60° Pharmaceuticals LLC Phase Not Applicable Planned 0 2020-07-17
Development of early warning and rapid response system for patients with novel coronavirus pneumonia (COVID-19): a research protocol Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Beijing Tsinghua Chang Gung Hospital, Tsinghua University National Natural Science Foundation of China China 2020-09-01 2021-08-31 ChiCTR2000034680 Phase Not Applicable Not yet recruiting 2 12 Months 200 Hua Zhou, Yuan Xu 2020-07-20
Siddha Treatment for COVID 19- a Pilot Study Coronavirus disease 19 infection Variable regimens including AAdathodai kudineer , bramanandha bairava mathirai , thaalisathi chooranam +thulasi chooranam +pavala parpam , thoothuvalai nei Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Dr Ambedkar arts college, Government Siddha Medical College India 2020-07-27 CTRI/2020/07/026632 Phase 2 Clinical Not yet recruiting 1 40 Dr J Nikil Niva, Dr R Sasirekha 2020-07-22
Uses of herbal combination by taking it in hot water in covid 19 positive patients Coronavirus disease 19 infection Variable regimens including Alpinia officinarum , Anethum sowa , Cuminum cyminum , Curcuma long , Justicia adhatoda , Melia Dubia , Mollugo serviana , Piper nigrum , Zingiber officinale Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kumarans fertility centre, Murugaa herbal research trust India 2020-07-19 CTRI/2020/07/026631 Phase Not Applicable Not yet recruiting 2 30 Dr Johnson Amalraj, Dr S Saravanan 2020-07-21
Spartan COVID-19 System: Evaluation of Clinical Sample Collection Coronavirus disease 19 infection Spartan COVID-19 System alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Spartan Bioscience Inc Humber River Hospital, The Ottawa Hospital Canada 2020-06-28 2020-08-01 NCT04473248, VNV-00552 Phase Not Applicable Recruiting 2 1 Month 30 Derek So, MD, Jamie Spiegelman, MD, Tara Linseman, MSc 2020-07-20
Clinical trial of ACT 12 tablet and ACT 13 dry syrup in Covid 19 patients Coronavirus disease 19 infection standard of care alone, ACT 12 plus ACT 13 Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) GPLIFE HEALTHCARE PRIVATE LIMITED India 2020-07-22 CTRI/2020/07/026630, MHC/CTH/20-21/002 Phase 2 Clinical Not yet recruiting 2 60 Dr Patsute Sudhir Dadaram, Dr Pawan Kumar Singh, Dr Shridhar Pandya, VGVaidya 2020-07-21
Psycho-social Problems among COVID Infection Survivors Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression, Psychiatric disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sanjay Gandhi Postgraduate Institute of Medical Sciences India 2020-07-24 CTRI/2020/07/026612 Phase Not Applicable Not yet recruiting 5 100 Dr Anshul Jain, Dr Himanshu Reddy, Dr Mallikarjun Gunjiganvi, Dr Rajeev Puri, Dr Vipin Dhama 2020-07-21
COVID-19 in Patients With Anosmia in Egypt Coronavirus disease 19 infection, Dysgeusia, Dysomia, Viral respiratory tract infection RT-PCR alone, standard management protocol alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ain Shams University Egypt 2020-07-01 2020-10-30 FMASU P45A/2020, NCT04473157 Phase Not Applicable Recruiting 1 3 Months 50 Ossama I Mansour, MD 2020-07-20
GOTCHA: Glitazone Treatment for Coronavirus Hypoxia, a Safety and Tolerability, Open-label With Matching Cohort, Pilot Study Coronavirus disease 19 infection, Hypoxia pioglitazone alone, standard of care alone Insulin sensitizer, PPAR gamma agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Samaritan Health Services US 2020-05-21 2021-06-01 GOTCHA, IRB20-042, NCT04473274 Phase 4 Clinical Recruiting 1 12 Months 20 Anthony Franklin, Brian Delmonaco, Brian Delmonaco, MD 2020-07-22
Safety and Efficacy of Melatonin in Outpatients Infected With COVID-19 (COVID-19) Coronavirus disease 19 infection melatonin (5-methoxy-N-acetyl tryptamine) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University at Buffalo US 2020-08-11 2021-08-10 NCT04474483, UBMELCOVID19 Phase 2 Clinical Not yet recruiting 1 12 Months 30 Margarita Dubocovich, Ph.D., Margarita L Dubocovich, Ph.D., Sanjay Sethi, MD 2020-07-20
ROPRICo: ROPRICo Coronavirus disease 19 infection HOSPITAL SIBU Malaysia 2020-08-01 2021-03-31 1.3, 55773, NMRR-20-1466-55773, ROPRICo Phase Not Applicable Not yet recruiting 1 8 Months Dr Jeffrey Lee Soon Yit, Dr. Toh Teck Hock 2020-07-30
Burnout Among Critical Care Personnel in ICU During COVID-19 Pandemic Coronavirus disease 19 infection Hospital Raja Permaisuri Bainun Malaysia 2020-07-31 2020-12-31 55681, BURN01, NMRR-20-1459-55681 Phase Not Applicable Not yet recruiting 1 5 Months Dr Foong Kit Weng, Dr LEONG E LI 2020-07-17
COVID-19 Detection Tests in Different Body Fluids Coronavirus disease 19 infection qRT-PCR alone Healthy volunteers accepted, Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Nucleo De Pesquisa E Desenvolvimento De Medicamentos Da Universidade Federal Do Ceara Federal University of Ceara Brazil 2020-07-31 2021-09-30 COVID FLUIDS, NCT04473352 Phase Not Applicable Not yet recruiting 1 14 Months 80 Eduardo P Miranda, PhD, Ricardo Reges, PhD 2020-07-21
Herbal formulation for immunity boosting during pandemic Coronavirus disease 19 infection Herbal Formulation alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) ayurved mahavidyalaya, nashik India 2020-07-13 CTRI/2020/07/026528 Phase Not Applicable Not yet recruiting 1 500 Aparna Abhay Raut, Shailaja Prakash Chondikar 2020-07-20
Mental health among Malaysian healthcare workers in the midst of COVID-19 pandemic Coronavirus disease 19 infection JABATAN KESIHATAN NEGERI SELANGOR Malaysia 2020-08-01 2021-07-31 55564, NMRR-20-1467-55564 Phase Not Applicable Status not specified 1 12 Months DR MOHD FADHLI BIN MOHD FAUZI 2020-07-20
I-COVID-PK: Efficacy of Iodine Complex Against COVID-19 Patients Coronavirus disease 19 infection iodine complex capsule alone, iodine complex syrup alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Federal Postgraduate Medical Institute MTI Medical Private Limited Pakistan 2020-07-14 2020-09-30 I-COVID-PK, NCT04473261, SZMC/IRB/INTERNAL/216/2020 Phase 1/Phase 2 Clinical Recruiting 1 2 Months 30 Moneeb Ashraf, MBBS, Muhammad Ahmad Imran, Muhammad Ahmad Imran, MBBS, Muhammad Ashraf, PhD, Shoaib Ashraf, PhD, Sohaib Ashraf, Sohaib Ashraf, MBBS, Uzma Nasim, FCPS 2020-07-24
Profile-Cov: Rapid Diagnostic Profiling of SARS-CoV-2 Coronavirus disease 19 infection Healthy volunteers accepted Mekelle University Academic Medical Center, University of Amsterdam, Ethiopian Public Health Institute, Liverpool School of Tropical Medicine Ethiopia 2020-07-20 2021-06-30 NCT04473365, Profile-Cov, RIA2020EF-2905 Phase Not Applicable Not yet recruiting 1 11 Months 186 Amanuel Haile, MD, Dawit Wolday, MD, PhD, Prof. Dawit Wolday 2020-07-20
COVID19 with Olfactory Impairment Coronavirus disease 19 infection, Hearing disorder Universiti Kebangsaan Malaysia Malaysia 2020-07-13 2020-12-31 55312, NMRR-20-1448-55312 Phase Not Applicable Recruiting 1 5 Months DR SALINA BINTI HUSAIN, OUI TING JIE 2020-07-20
A study to assess safety and efficy of Octagam in the treatment of Covid-19 Coronavirus disease 19 infection Octagam alone Octapharma AG Turkey Phase Not Applicable Status not specified 1 93 Figen Esen., Wolfgang Frenzel, 2020-07-20
SOVID: Surgical Outcomes in COVID-19 Patients (SOVID) Coronavirus disease 19 infection, Surgical procedure Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sanjay Gandhi Postgraduate Institute of Medical Sciences India 2020-07-24 CTRI/2020/07/026611, SOVID Phase Not Applicable Not yet recruiting 6 50 Dr Mallikarjun Gunjiganvi, Dr Neeraj Baronia, Dr Richa Jaiman, Dr Shabir Ahmad, Girish, Puneet 2020-07-21
A Multicenter Study Evaluating Clinical Course in Patients With COVID-19 and Its Relationship to Cytokine Storm Coronavirus disease 19 infection, Immune disorder, Sepsis Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hadassah Medical Organization Barzilai medical center, Chaim Sheba Medical Center Israel 2020-06-28 2020-12-01 DM002, NCT04474067 Phase Not Applicable Recruiting 1 5 Months 300 Dror Mevorach, MD 2020-07-20
CPRC: The COVID-19 PUI Reality Check (CPRC) Study Coronavirus disease 19 infection immune assay alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bassett Healthcare BioReference Laboratories US 2020-07-15 2021-07-31 1613182, CPRC, NCT04474288 Phase Not Applicable Not yet recruiting 1 12 Months 400 Catherine Gilmore, RN, Daniel Freilich, MD, Jennifer Victory, RN, daniel freilich, MD 2020-07-20
SPESELPIS: This Phase 1 clinical trial of NT-I7 is a multi-center, double-blind, randomized, placebo-controlled study that will evaluate the safety and efficacy of NT-I7 in adult patients with mild COVID-19 Coronavirus disease 19 infection efineptakin alfa alone IL-7 receptor agonist, Interleukin-7 ligand National Institute of Allergy and Infectious Diseases, National Institutes of Health, NeoImmuneTech Inc, University of Nebraska Medical Center National Institute of Allergy and Infectious Diseases, National Institutes of Health, University of Nebraska Medical Center SPESELPIS, SPESELPIS Phase 1 Clinical Not yet recruiting 0 Andre Kalil, M.D., M.P.H, NgocDiep 2020-07-17
A clinical study to observe the effects of 8.4% sodium bicarbonate impregnated steam inhalation on Covid-19 infected patients Coronavirus disease 19 infection sodium bicarbonate alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Welcare Hospital Myself Health Check Ltd India 2020-07-20 CTRI/2020/07/026535 Phase 2 Clinical Not yet recruiting 1 60 Dr Bharat S Mody, Dr Kshitij B Mody 2020-07-20
A Phase I clinical trial of IDB-003 for potential treatment of SARS-CoV-2 infection Coronavirus disease 19 infection IDB-003 alone Angiotensin converting enzyme 2 inhibitor, COVID19 Spike glycoprotein modulator IDBiologics 2020-09-30 Phase 1 Clinical Planned 0 2020-07-17
Physiotherapy as a Complimentary Treatment in Reducing Viral-Load, Complications, Death, Expedite Discharge and Improve Quality of Life, Exercise Endurance and Capacity in Stroke Survivors With CoViD-19: A Clinical-Controlled Study Coronavirus disease 19 infection, Stroke Rehabilitation exercise protocol alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidad De Los Lagos Bayero University Kano Nigeria 2020-07-13 2021-12-31 CMUL/HREC/06/20/742, NCT04471831, PACTR202007589336711 Phase Not Applicable Not yet recruiting 1 17 Months 30 Caleb AO Gbiri, PhD, Jibrin S Usman, MSc 2020-07-27
BEAT-CORONA: Building evidence to advance treatments for COVID-19 Coronavirus disease 19 infection Cambridge University Hospitals NHS Foundation Trust, University of Cambridge NIHR Cambridge Biomedical Research Centre UK 2020-04-06 2025-04-30 2020-002016-48, BEAT-CORONA, CTU0306, IRAS 282317, ISRCTN89573163 Phase Not Applicable Recruiting 1 60 Months Dr Brusby, Dr Thomas F Hiemstra 2020-07-20
Study of antiviral nutraceutical PICOVRID in COVID 19 patients Coronavirus disease 19 infection PICOVRID alone, Standard care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Indian Institute Of Technology Mumbai Government Medical College, Nagpur India 2020-07-20 CTRI/2020/07/026534 Phase 3 Clinical Not yet recruiting 1 70 Dr Rinti Banerjee, Dr Sushant Meshram 2020-07-20
Comparison to two different position to relieve difficulty in breathing in COVID- 19 patients Coronavirus disease 19 infection, Viral pneumonia Repeated Position Change alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Medical Sciences India 2020-07-14 CTRI/2020/07/026532 Phase Not Applicable Not yet recruiting 1 90 Dr Souvik Maitra 2020-07-20
Indian SARS-CoV2 Host Genetics Consortium Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Asian Ancestry MedGenome Labs Pvt Ltd Narayana Hrudayalaya LTD India 2020-08-01 CTRI/2020/07/026531 Phase Not Applicable Not yet recruiting 1 3000 Dr Alben Sigamani 2020-07-20
REDMIC: A clinical trial to study the effects of two drugs methylprednisolone and dexamethasone in patients with severe COVID-19 Coronavirus disease 19 infection methylprednisolone alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chettinad Hospital And Research Institute India 2020-07-27 CTRI/2020/07/026608, REDMIC Phase 2 Clinical Not yet recruiting 1 40 Dr Ananthakumar P K, Prof V R Mohan Rao 2020-07-20
A phase II clinical trial of DPX-COVID-19 for the potential treatment of COVID-19 infection Coronavirus disease 19 infection DPX-COVID-19 alone IMV Inc 2020-12-31 Phase 2 Clinical Planned 0 2020-07-17
MH Outcomes Selangor Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression JABATAN KESIHATAN NEGERI SELANGOR Malaysia 2020-08-17 2021-03-17 55191, NMRR-20-1485-55191 Phase Not Applicable Status not specified 1 7 Months Dr Rohaida Binti Ismail, Dr Siti Sara binti Yaacob 2020-07-20
NC4R Coronavirus disease 19 infection Selayang Hospital Malaysia 2020-07-27 2020-09-30 55708, NMRR-20-1477-55708 Phase Not Applicable Status not specified 17 2 Months Hafiz Git Kim Ann 2020-07-30
Psychosocial COVID Coronavirus disease 19 infection Hospital Sungai Buloh Malaysia 2020-07-15 2020-10-31 55169, NMRR-20-1475-55169 Phase Not Applicable Status not specified 1 3 Months Dr Lee Pei Yin 2020-07-20
CovConDa-Study: COVID-19 safe anesthetic gas measurement with the AnaConDaS system Coronavirus disease 19 infection AnaConDaS system alone, isoflurane alone, sevoflurane alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Katholisches Klinikum Bochum Germany 2020-07-26 20-6938, CovConDa-Study, DRKS00022479 Phase Not Applicable Not yet recruiting 1 14 Mr. Dr. Martin Bellgardt 2020-07-17
Role of Herbal Immunomodulators in in Boosting the Immunity among healthcare workers assigned to COVID-19 wards Coronavirus disease 19 infection Guduchi plus Immusante Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Himalaya Drug Co India 2020-07-24 CTRI/2020/07/026579, HDC/CP/PP/036/2020 Version 1.0 Phase 3 Clinical Not yet recruiting 1 100 Dr C R Jayanthi, Dr Palaniyamma D, Dr Soorya Narayan H 2020-07-20
Sahadevi Choorna for COVID 19 Coronavirus disease 19 infection Sahadevi Powder alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Parul Institute of Ayurved India 2020-07-20 CTRI/2020/07/026575 Phase 2 Clinical Not yet recruiting 1 48 Dr Nandakishor P Umale 2020-07-20
To assess the seriousness in COVID-19 patients with the blood test report Coronavirus disease 19 infection Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences India 2020-07-20 CTRI/2020/07/026574 Phase Not Applicable Not yet recruiting 1 100 Yudhyavir Singh 2020-07-20
Pattern of ocular surface involvement in COVID-19 patients in Hassan, Karnataka Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hassan institute of medical sciences India 2020-07-21 CTRI/2020/07/026571 Phase 3 Clinical Not yet recruiting 1 100 Dr Sandeep K 2020-07-20
Evaluation of atorvastatin tablet as an adjuvant treatment for patients with mild to moderate COVID-19 in Qaem Hospital, Mashhad Coronavirus disease 19 infection, Viral pneumonia atorvastatin alone HMG CoA reductase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Mashhad University of Medical Sciences Iran 2020-07-21 IR.MUMS.REC.1399.221, IRCT20200408046990N3 Phase 2 Clinical Recruiting 1 40 Mohsen Tafaghodi, Sepideh Elyasi 2020-07-21
A phase III cinical trial of AZD-1222 for the treatment of Coronavirus disease 19 infection Coronavirus disease 19 infection AZD-1222 alone COVID19 Spike glycoprotein modulator AstraZeneca plc Biomedical Advanced Research and Development Authority (BARDA), US Department of Health and Human Services US Phase 3 Clinical Planned 1 30000 2020-07-23
Acupressure for COVID-19 Related Quality of Life and Stress Acute stress disorder, Coronavirus disease 19 infection Self-acupressure alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of California Los Angeles US 2020-07-25 2021-02-25 20-000773, NCT04472559 Phase Not Applicable Not yet recruiting 1 7 Months 200 Kakit P. Hui, MD, Ryan Abbott, MD, PhD 2020-07-21
Locally Produced Cloth Face Mask and COVID-19 Like Illness Prevention Ageusia, Coronavirus disease 19 infection, Cough, Dysomia, Dyspnea, Fever, Respiratory disease Certified cloth face mask alone, Information on COVID-19 prevention alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bandim Health Project Engineers without Borders, Denmark, University of Southern Denmark Guinea-Bissau 2020-07-20 2020-11-30 BHP MASK01, NCT04471766 Phase Not Applicable Recruiting 1 4 Months 66000 Amabelia Rodrigues, PhD 2020-07-24
COVA: Testing the Efficacy and Safety of BIO101 for the Prevention of Respiratory Deterioration in COVID-19 Patients Coronavirus disease 19 infection, Respiratory disease, Respiratory distress syndrome, Viral pneumonia 20‐hydroxyecdysone (oral, sarcopenia/sarcopenic obesity/Duchenne muscular dystrophy/ARDS associated with COVID-19), BIOPHYTIS alone Proto-oncogene Mas agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) BIOPHYTIS US, France, Belgium, UK 2020-06-16 2021-09-30 2020-001498-63, BIO101-CL05, COVA, NCT04472728 Phase 2/Phase 3 Clinical Recruiting 4 15 Months 310 Capucine Morelot-Panzini, MD, Dr Muriel Lins, Mounia Chabane De Saint Aubin, Muriel Lins, MD, Shmuel Agus, MD, Waly Dioh, PhD 2020-07-31
Study of an Ayurveda regimen in COVID Positive patients Coronavirus disease 19 infection Dasamoolakadutrayadi Kashayam   alone, Guluchyadi Kwatham alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Deenanath Mangeshkar Hospital and Research Center India 2020-07-24 CTRI/2020/07/026602 Phase 2 Clinical Not yet recruiting 1 72 Dr Pankaj Wanjarkhedkar 2020-07-20
A study to check effect of an Ayurvedic treatment on corona positive patients Coronavirus disease 19 infection conventional treatment alone, Variable regimens including Bilvadi , Surasadi Kadha , Vironil Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Aarti Foundation, Kutchhi Jain Foundation District Civil Hospital Beed India 2020-07-21 CTRI/2020/07/026601 Phase 2/Phase 3 Clinical Not yet recruiting 1 70 DrShivprasad Charkha 2020-07-20
An expansive subject study to evaluate the efficacy of AZD-1222 for the potential prevention of COVID-19 infection Coronavirus disease 19 infection AZD-1222 alone COVID19 Spike glycoprotein modulator AstraZeneca plc, IQVIA Holdings Inc US Phase Not Applicable Planned 1 2020-07-17
Expanded Access to Convalescent Plasma for Treatment of COVID-19 Coronavirus disease 19 infection, Dyspnea, Multiple organ failure, Respiratory failure, Septic shock convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hackensack Meridian Health US NCT04472572, PRO2020-0663 Phase Not Applicable Suspended 1 Michele Donato 2020-07-20
Nelfinavir and Favipiravir Combination in Newly Diagnosed COVID19 Egyptian Patients Coronavirus disease 19 infection favipiravir plus nelfinavir HIV protease inhibitor, HIV-1 protease inhibitor, RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Tanta University Egypt 2020-08-31 2020-12-31 NCT04471662, NELFINAVIR/FAVIPIRAVIR Phase 2 Clinical Not yet recruiting 1 4 Months 50 Nahla El-Ashmawy, PhD 2020-07-20
COLSTAT: Colchicine/Statins for the Prevention of COVID-19 Complications (COLSTAT) Trial Coronavirus disease 19 infection Standard of care alone, colchicine plus rosuvastatin HMG CoA reductase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Yale University US 2020-08-01 2022-08-01 2000027950, COLSTAT, NCT04472611 Phase 3 Clinical Not yet recruiting 1 24 Months 824 Alexandra Lansky, MD, Marianne McCarthy, MBA 2020-07-20
RETURN: Repeated Employee Testing for Understanding the Recovery to Normal Coronavirus disease 19 infection ELISA alone, biological sampling alone, polymerase chain reaction alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cincinnati Children's Hospital Medical Center US 2020-05-11 2023-12-31 NCT04472793, RETURN, RETURN Phase Not Applicable Recruiting 1 43 Months 200 Mary Allen Staat, MD, MPH, Maureen Carolin, Russell Ware, MD, PhD, Teresa Latham 2020-07-20
A randomized, contrlled clinical trial on adjuvant TCM herbal treatment to prevent deterioration and improve outcome of COVID-19 patients in Singapore Coronavirus disease 19 infection TCM herbal alone Singapore General Hospital Pte Ltd Singapore TCMC19-P2 Phase 3 Clinical Status not specified 1 Dr Tan Thuan Tong, Jamie Chien Mei Fong 2020-07-17
SINZ-COVID-PK: Efficacy of Subcutaneous Ivermectin With or Without Zinc and Nigella Sativa in COVID-19 Patients Coronavirus disease 19 infection ivermectin (Montpellier) alone, standard care alone, Variable regimens including Nigella Sativa/Black Cumin extract , ivermectin (Montpellier) , zinc sulphate Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Federal Postgraduate Medical Institute Pakistan 2020-07-14 2020-09-30 NCT04472585, SINZ-COVID-PK, SZMC/IRB/INTERNAL/215/2020 Phase 1/Phase 2 Clinical Recruiting 1 2 Months 40 Moneeb Ashraf, MBBS, Muhammad Ahmad Imran, Muhammad Ahmad Imran, MBBS, Muhammad Ashraf, PhD, Shoaib Ashraf, PhD, Sohaib Ashraf, Sohaib Ashraf, MBBS 2020-07-19
Covid-19: Hydroxychloroquine and Covid in RA Patients Coronavirus disease 19 infection hydroxychloroquine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tanta University Egypt 2020-06-15 2020-09-30 002, Covid-19, NCT04471649 Phase Not Applicable Recruiting 1 3 Months 80 Asem Elfert, Prof, Mohammed Hassan Abu-Zaid, Mohammed Hassan Abu-Zaid, PhD, Samar A Tabra, PhD, Samar Tabra, PhD 2020-07-18
A Post Marketing Surveillance (PMS) study to monitor the efficacy and safety of FabiFlu in patients with COVID 19 Coronavirus disease 19 infection favipiravir alone RNA polymerase inhibitor Glenmark Pharmaceuticals Ltd India 2020-07-13 Phase 4 Clinical Recruiting 1 1000 2020-07-28
A multicenter prospective study utilizing Daxor’s BVA-100 (Blood Volume Analyzer, “BVA”) technology in hospitalized COVID-19 patients Coronavirus disease 19 infection Daxor’s BVA-100 alone Daxor Corp US 2020-07-15 Phase Not Applicable Recruiting 1 2020-07-22
Seroprevalence of Coronavirus Disease 2019 (COVID-19) Antibodies in a Vulnerable Neighbourhood, Buenos Aries Argentina Coronavirus disease 19 infection Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Italiano de Buenos Aires Hospital de Niños R. Gutierrez de Buenos Aires Argentina 2020-06-10 2020-07-18 1831, NCT04472078 Phase Not Applicable No longer recruiting 1 1 Month 873 Alicia Mistchenko, MD PHD, Ana M Gomez Saldaño, MD MG, Andrea Gamarnik, PHD, Fernan Quiroz, MD MG, Julieta Salto, Lorena Luna, MG, Magdalena Wagner Manslau, Silvana Figar, MD MG, Vanina L Pagotto, MD MG 2020-07-21
MR SPOC: Telemedicine in Outpatient Covid-19 Patients Arterial hypertension, Atrial fibrillation, Coronary artery disease, Coronavirus disease 19 infection, Diabetes mellitus, Diastolic heart failure, Myocardial infarction, Nicotine dependence, Systolic heart failure Withings ScanWatch alone, medical hotline telemedicine care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Ludwig-Maximilians University of Munich German Centre for Cardiovascular Research, Referat für Gesundheit und Umwelt (RGU), Landeshauptstadt München Germany 2020-08-31 2021-01-31 20-448, MR SPOC, NCT04471636 Phase Not Applicable Not yet recruiting 1 5 Months 600 Moritz F Sinner, MD, MPH, Moritz F. Sinner, Stefan Kääb, MD, PhD, Steffen Massberg, MD 2020-07-20
Frequency of Perforated Appendicitis in Times of COVID-19 Appendicitis, Coronavirus disease 19 infection appendectomy alone, cefotaxime plus metronidazole Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Tubingen Germany 2020-03-16 2020-05-31 AZ: 324/2020BO2, NCT04472052 Phase Not Applicable Completed 1 2 Months 143 2020-07-18
EPICOVID19: Italian Web-based Cross-sectional Survey on COVID-19 Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institute of Biomedical Technologies-National Research Council CNR Institute of Clinical Physiology, Institute of Neuroscience-National Research Council, Italian Society of Geriatrics and Gerontology, SOCIETA' ITALIANA MALATTIE INFETTIVE E TROPICALI, Universita degli Studi di Milano Italy 2020-04-13 2020-08-31 EPICOVID19, EPICOVID19_2020, NCT04471701 Phase Not Applicable Recruiting 1 4 Months 200000 Federica Prinelli, PhD, Fulvio Adorni, MPH 2020-07-27
A clinical trial of 2X-121 for the tretment of Coronavirus disease 19 infection Coronavirus disease 19 infection 2X-121 alone Poly ADP ribose polymerase 1 inhibitor, Poly ADP ribose polymerase 2 inhibitor, Tankyrase-1 inhibitor, Tankyrase-2 inhibitor National Institutes of Health, Oncology Venture A/S Northern Arizona University Phase Not Applicable Planned 0 2020-07-16
A randomized, double-blind, placebo-controlled, investigator-sponsored study to evaluate the safety and efficacy of vadadustat for hypoxemia due to COVID-19, the disease caused by SARS-CoV-2 Coronavirus disease 19 infection, Hypoxia vadadustat alone HIF prolyl hydroxylase inhibitor, Hypoxia inducible factor inhibitor gene inhibitor, Hypoxia inducible factor-2 alpha modulator Akebia Therapeutics Inc, University of Texas Health Science Center Houston US 2020-07-14 Phase 3 Clinical Recruiting 1 300 Bentley J. Bobrow, Holger K. Eltzschig 2020-07-16
Systematic Assessment of SARS-CoV-2 Neurotropic Capacity in Modestly and Critically Ill Patients, and Patients Who Died From COVID-19 Coronavirus disease 19 infection CODEX fluorescent microscopy alone, CyTOF mass cytometry alone, OLINK Proximity Extension Assay alone, biological sampling alone, magnetic resonance imaging alone, multiplexed ion beam imaging alone, qPCR alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Basel University of Basel Switzerland 2020-09-30 2022-12-31 2020-01503, CH20HUTTER, NCT04472013 Phase Not Applicable Recruiting 2 27 Months 40 David Winkler, PD Dr. med., Gregor Hutter, Prof. Dr. med. 2020-07-23
A phase II/III trial to evaluate SARS-CoV-2 vaccine (VLP, COVID-19), Medicago for the prevention of Covid-19 Coronavirus disease 19 infection MT-2766 alone TLR-9 agonist Medicago Inc 2020-10-31 Phase 2/Phase 3 Clinical Planned 0 2020-07-17
Study of Abatacept in the Treatment of Hospitalized COVID-19 Participants With Respiratory Compromise Coronavirus disease 19 infection, Respiratory disease abatacept alone, standard of care alone Cytotoxic T-lymphocyte protein-4 stimulator, T cell surface glycoprotein CD28 inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bristol-Myers Squibb Co US 2020-07-20 2021-01-14 IM101-873, NCT04472494, U1111-1250-4217 Phase 2 Clinical Not yet recruiting 5 5 Months 129 Bristol-Myers Squibb, Site 0001, Site 0002, Site 0003, Site 0004, Site 0005 2020-07-25
A global study to assess safety and efficacy of itolizumab in patients with COVID-19 Coronavirus disease 19 infection itolizumab alone T-cell differentiation antigen CD6 inhibitor Equillium Inc US Phase Not Applicable Planned 1 2020-07-16
Lung ultrasound to predict invasive ventilation of patients with COVID-19 lung disease Coronavirus disease 19 infection lung ultrasound alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gold Coast Hospital, Monash University Canada, Ireland, US, Australia 2020-07-13 2021-12-31 ACTRN12620000734965, U1111-1254-7764 Phase Not Applicable Not yet recruiting 10 17 Months 1000 Dr Gabriel Bletcher, Dr Peter J Snelling 2020-07-17
Will treating the overwhelming patient response with medications affect COVID-19 mortality Coronavirus disease 19 infection losartan alone Angiotensin II AT-1 receptor antagonist, Angiotensin II receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) New South Wales Ministry of Health Australia 2020-09-01 ACTRN12620000731998p, U1111-1252-6251 Phase 1 Clinical Not yet recruiting 4 36 Prof Jennifer Martin 2020-07-17
A clinical, randomized study to evaluate the efficacy and safety of Naproxen compared to placebo in combination with Azithromycin or Levofloxacin in patients with Severe Acute Respiratory Syndrome during the Covid-19 pandemic Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia Variable regimens including amoxicillin + clavulanate , azithromycin , levofloxacin , naproxen , oseltamivir DNA gyrase inhibitor, Exo-alpha sialidase inhibitor, Topoisomerase IV inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital de Base de São José do Rio Preto, Sao Jose do Rio Preto University Brazil 2020-06-01 31047820.0.0000.5415, 4.063.234, RBR-3rywwg, U1111-1251-0662 Phase 2b Clinical Recruiting 1 192 Suzana Margareth Lobo 2020-07-27
Use of Anti-IL-17 in patients with Covid-19 associated pneumonia Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia secukinumab alone, standard treatment alone IL-17 antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundaçao de Amparo a Pesquisa do Rio Grande do Sul, Ministry of Science and Technology, Brazil, NOVARTIS BIOCIENCIAS S.A. Conselho Nacional de Desenvolvimento Cientifico e Tecnologico - CNPq, Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, FAPEMIG, Hospital Risoleta Tolentino Neves Brazil 2020-07-10 32224420.3.0000.0008, 4.100.115, A03746497663, Nº 11/2020, RBR-5vpyh4 Phase 2 Clinical Not yet recruiting 1 50 GUSTAVO GOMES RESENDE 2020-07-17
MuSPAD: Multi-local and serial, cross-sectional, prevalence study on antibodies against SARS-CoV-2 (COVID-19) in Germany Coronavirus disease 19 infection serological test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Helmholtz Zentrum fur Infektionsforschung GmbH Bundesministerium fur Bildung und Forschung, Deutsche Forschungsgemeinschaft (DFG), German Federal Ministry of Education and Research, NaturWissenschaftliches Und Medizinisches Institut An Der Universitaet Tuebingen In Reutlingen Germany 2020-07-01 9086_BO_S_2020, DRKS00022335, MuSPAD Phase Not Applicable Recruiting 4 60000 Daniela Gornyk, Gérard Krause 2020-07-17
COVID-19 cohort Würzburg: Prospective collection of data and biomaterial of COVID-19 at the location Würzburg Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Würzburg Germany 2020-05-15 89/20-sc, COVID-19 cohort Würzburg, DRKS00022402 Phase Not Applicable Recruiting 1 400 *** *** 2020-07-17
COVID-19 IgG Antibodies in the Serum of Recovered Patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assiut University Egypt 2020-08-01 2021-09-01 COV-PH2020, NCT04470414 Phase Not Applicable Not yet recruiting 1 13 Months 100 Mahmoud A. Abd El Aty, Prof., Mariam Amin, Mariam T. Amin 2020-07-17
Relation Between Lab Finding and COVID-19 Severity Coronavirus disease 19 infection CELL-DYN 3700 alone, Liver function test alone Assiut University Egypt 2020-07-15 2020-12-01 NCT04470557, RLCS Phase Not Applicable Not yet recruiting 1 4 Months 100 Anwar M. Ali, Doctorate, Anwar Mohamed Ali, Esam_eldeen M. Abdalla, Doctorate, Ghydaa A. Shehata, Doctorate, Heba Abdellatif, Doctorate 2020-07-16
PULDAMCO: Pulmonary Damage after hospitalization for acute Covid‐19 (PULDAMCO), an exploratory, prospective, cohort study Coronavirus disease 19 infection CT angiography alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Radboud University Medical Center Nijmegen Netherlands 2020-07-07 2021-07-29 2020-6637, NL8765, PULDAMCO Phase Not Applicable Recruiting 1 12 Months 150 Bram van den Borst 2020-07-19
Impact on the OLAF Intervention to Prevent Post Traumatic Disorders During the Confinement Coronavirus disease 19 infection, Post traumatic stress disorder OLAF intervention alone, Phone call alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire de Toulouse France 2020-06-12 2021-10-12 NCT04470869, RC31/20/0190 Phase Not Applicable Recruiting 1 16 Months 130 Guillaume Ducos, MD, Juliette SALLES, MD 2020-07-20
Changes in Cellular Immune Profile During COVID-19 Infection Coronavirus disease 19 infection Leukapheresis alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Seraph Research Institute Scripps Research Institute US 2020-04-15 2020-12-31 NCT04470999, SRPH-CVD-01 Phase Not Applicable Recruiting 0 8 Months 25 Gregory T Howell, BA Psy, Kristen Terry, Serhat Gumrukcu, MD PhD 2020-07-22
COVID-19 Infection at Samusocial in Paris: Descriptive and Serological Survey Coronavirus disease 19 infection bood test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) INSERM Assistance Publique Hopitaux de Paris, Samusocial de Paris France 2020-07-31 2020-11-30 C20-50, NCT04470648 Phase Not Applicable Not yet recruiting 3 4 Months 220 Anne Rachline, MD, Armelle Pasquet, MD, Yazdan Yazdanpanah, MD PHD 2020-07-22
The Prevalence of persistent viral shedding and antibody levels among recovered COVID-19 patients of the hospitals and Public Health Centers under Bangkok Metropolitan Administration Coronavirus disease 19 infection Chulalongkorn University Thailand 2020-06-10 TCTR20200708001 Phase Not Applicable Recruiting 1 239 Chintana Chirathaworn, Pijaya Nagavajara, Yong Poovarawan 2020-07-16
Serosurvey for antibodies against SARS-CoV-2 in Pune city Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) IISER Pune India 2020-07-20 CTRI/2020/07/026509 Phase Not Applicable Not yet recruiting 1 1520 Aarti Nagarkar, Aurnab Ghose, L S Shashidhara 2020-07-16