Last updated: Aug 08, 2020 - 02:00 BST

Title Indication Intervention Actions PatientSelection Sponsor Collaborator Country StartDate EndDate Identifiers Phase Recruitment Status Sites Trial Duration Enrollment Count Contacts LastChanged
Behavior During and After COVID-19-crisis Coronavirus disease 19 infection, Sleep disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Bern University of Applied Sciences Switzerland 2020-04-01 2022-12-31 BFH CORONA, NCT04502108 Phase Not Applicable Recruiting 0 33 Months 1000 Heiner Baur, Ph.D, Slavko Rogan, Slavko Rogan, Ph.D 2020-08-07
Study to Evaluate the Efficacy and Safety of Remdesivir (GS-5734) Treatment of Coronavirus Disease 2019 (COVID-19) in an Outpatient Setting Coronavirus disease 19 infection remdesivir alone COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gilead Sciences Inc 2020-09-30 2021-01-31 2020-003510-12, GS-US-540-9012, NCT04501952 Phase 3 Clinical Not yet recruiting 0 4 Months 1230 Gilead Clinical Study Information Center, Gilead Study Director 2020-08-07
PHYTCOVID-19: Phytomedicines Versus Hydroxychloroquine as an Add on Therapy to Azythromycin in Asymptomatic COVID-19 Patients Coronavirus disease 19 infection azithromycin alone, plant species powder alone, Variable regimens including Quinquina-Stevia , azithromycin , hydroxychloroquine Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institute for Research and Development of Medicinal and Food Plants of Guinea Guinea 2020-06-01 2020-09-30 IRDPMAG, NCT04501965, PHYTCOVID-19 Phase 2 Clinical Recruiting 0 4 Months 231 Mamadou A Baldé, Mohamed Cissé, Saliou Sow 2020-08-07
Short-term Impact of COVID-19 Lockdown on Metabolic Control of Type 2 Diabetes Coronavirus disease 19 infection, Non-insulin dependent diabetes antidiabetic treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Pisa Italy 2020-03-11 2020-06-30 AS0007, NCT04501991 Phase Not Applicable Completed 0 3 Months 114 Anna Solini, MD, PhD 2020-08-07
Impact of Spectacles on Compliance to Mask-wearing Directives Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Of Thrace Greece 2020-06-25 2020-08-14 ES8/TH5/25-06-2020, NCT04501172 Phase Not Applicable No longer recruiting 1 1 Month 1214 Labiris Georgios, MD, PhD 2020-08-07
Prospective Study initiated by University Hospital Rostock concerning COVID-19 in mothers, nursery and school teachers of children in Rostock Coronavirus disease 19 infection biological sampling alone, polymerase chain reaction alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Universitätsmedizin Rostock Deutsche Forschungsgemeinschaft (DFG), German Federal Ministry of Education and Research, Land Mecklenburg-Vorpommern Germany 2020-08-10 A 2020-0090, DRKS00022504 Phase Not Applicable Recruiting 0 600 Emil C. Reisinger, Hilte Geerdes-Fenge 2020-08-07
Evaluating the effect of Ivermectin on COVID-19 patients Coronavirus disease 19 infection ivermectin alone Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ahvaz University of Medical Sciences Iran 2020-07-30 IR.AJUMS.REC.1399.322, IRCT20200404046937N4 Phase 2 Clinical Recruiting 2 60 Mehran Varnaseri, Mehran Varnasseri, Mohammad Badavi 2020-08-07
A clinical study to evaluate the effect of BioTech Life Sciences proprietary formulas on long-term patient symptoms related to COVID-19 Post-Viral Fatigue (long-haulers) and chronic fatigue syndrome Chronic fatigue syndrome, Coronavirus disease 19 infection proprietary formulas, BioTech Life Sciences alone BioTech Life Sciences Phase Not Applicable Recruiting 0 2020-08-07
A phase II clinical trial of VBI-2900 for the potential treatment of SARS-CoV-2 infection Coronavirus disease 19 infection VBI-2901 alone VBI Vaccines Inc 2020-12-31 Phase 2 Clinical Planned 0 2020-08-07
Efficacy of Vitamin D Treatment in Pediatric Patients Hospitalized by COVID-19 Coronavirus disease 19 infection, Respiratory disease cholecalciferol alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) Coordinacion de Investigacion en Salud Hospital General de Mexico, Hospital Infantil de Mexico Federico Gomez Mexico 2020-07-15 2021-04-30 NCT04502667, R-2020-3603-020 Phase 3 Clinical Recruiting 1 9 Months 40 Carla Castuera Martinez, Carmen Espinosa-Sotelo, MD, Guadalupe Miranda-Novales, PhD, JESSIE ZURITA-CRUZ, JESSIE ZURITA-CRUZ, PhD, Jessie N ZURITA-Cruz, Jessie ZURITA-CRUZ, Mardia Lopez-Alarcon, PhD, Miguel Angel Villasis-Keever, Miguel Villasis-Keever, PhD 2020-08-07
A Phase III study of LY-CoV555 to determine if the investigational therapeutic can prevent either hospitalization or death through study day 28 Coronavirus disease 19 infection LY-CoV555 alone COVID19 Spike glycoprotein modulator National Institute of Allergy and Infectious Diseases, National Institutes of Health Phase 3 Clinical Status not specified 0 2020-08-07
Fiberoptic Bronchoscopy and Bronchoalveolar Lavage in Critically Ill Ventilated Patients Coronavirus disease 19 infection, Respiratory disease PulmoVista 500 (Draeger) alone, bronchoalveolar lavage analysis alone, electrical impedance tomography alone, fiberoptic bronchoscopy alone, multiple arterial blood gas test alone, realtime thoracic impedance analysis alone, sodium chloride alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Erasme Hospital Belgium 2020-08-06 2020-09-30 NCT04502368, P2020/375, SRB2020-289 Phase Not Applicable Not yet recruiting 0 1 Month 15 Francesco Ricottilli, MD, Leda Nobile, MD 2020-08-07
ACTIV-2: A Phase II clinical trial to evaluate the safety and efficacy of LY-CoV555 for COVID-19 Coronavirus disease 19 infection LY-CoV555 alone COVID19 Spike glycoprotein modulator National Institute of Allergy and Infectious Diseases, National Institutes of Health US ACTIV-2 Phase 2 Clinical Status not specified 1 Davey Smith, David Wohl, Kara W. Chew 2020-08-07
One-year Cardiac Follow-up of Patients With COVID-19 Pneumonia Cardiovascular disease, Coronavirus disease 19 infection, Viral pneumonia clinical test alone, instrumental test alone, laboratory diagnostics tests alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Federal Noe G Bjudzhetnoe Uchrezhdenie Nii Onkologii Sib Otdel Rossijskoj Akademii Med Nauk Fgbu Nii Russian Federation 2020-07-19 2021-12-31 NCT04501822, TCRC-COVID Phase Not Applicable Recruiting 1 17 Months 380 Elena Yaroslavskaya, PhD, Ivan Bessonov, PhD 2020-08-07
Inova-CCP: Open-label Treatment of Severe Coronavirus Disease 2019 (COVID-19) With Convalescent Plasma Coronavirus disease 19 infection COVID-19 convalescent plasma (CCP) transfusion alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Inova Health Care Services US 2020-06-06 2021-12-31 INOVA COVID-19 CCP, Inova-CCP, NCT04502472 Phase 2/Phase 3 Clinical Recruiting 1 18 Months 200 Anne Brown, M.D., Anne W Brown, MD, Edwinia Battle, BSN, Merte Lemma-Woldehanna, BS, Merte Lemme-Woldehanna, BS 2020-08-07
Opaganib-RHB: Treatment of COVID-19 With Opaganib in Patients With Pneumonia Requiring Oxygen Coronavirus disease 19 infection, Viral pneumonia opaganib alone Dihydroceramide delta 4 desaturase inhibitor, Sphingosine kinase 2 inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) RedHill Biopharma Ltd Israel 2020-08-31 2021-06-30 ABC-112, NCT04502069, Opaganib-RHB Phase 1/Phase 2 Clinical Not yet recruiting 1 10 Months 50 Mark L Levitt, MD, Mark Levitt, MD, Maskit Bar-Meir, MD 2020-08-07
A clinical trial of cannabinoid Sol-gel for the treatment of covid-19 Coronavirus disease 19 infection cannabinoid Sol-gel alone PreveCeutical Medical Inc, Veristat, Inc. Phase Not Applicable Planned 0 2020-08-07
Exhaled Breath Particles as a Clinical Indicator for Lung Injury and Acute Respiratory Distress Syndrome (ARDS) Acute lung injury, Coronavirus disease 19 infection, Lung infection, Respiratory distress syndrome exhaled breath particles PCR test alone, real time particle flow rate prediction test alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Skåne University Hospital Sweden 2020-05-01 2024-05-01 NCT04503057, PEX ARDS Phase Not Applicable Recruiting 1 48 Months 300 Leif Pierre, PhD, Sandra Lindstedt Ingemansson, MD, PhD 2020-08-07
CODIS: Cardiac Rehabilitation and Ongoing Physical Activity During COVID-19 Cardiovascular disease, Coronavirus disease 19 infection cycle ergometry test alone, semi-structured qualitative interview alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ludwig Boltzmann Institute for Digital Health and Prevention Institute of Sports Medicine, Prevention and Rehabilitation Austria 2020-07-14 2020-12-31 23_CODIS, CODIS, NCT04501432 Phase Not Applicable Recruiting 1 5 Months 40 Josef Niebauer, Prof.Dr.Dr., Mahdi Sareban, Dr. Dr. med., Mahdi Sareban, Dr.Dr.med., Stefan T Kulnik, PhD MRes 2020-08-07
Intravenous Immunoglobulin (IVIG, Bioven) Efficacy Assess for COVID-19/SARS-CoV-2 Severe Pneumonia Complex Treatment Coronavirus disease 19 infection, Lung inflammation, Respiratory distress syndrome, Respiratory failure, Respiratory tract infection, Viral pneumonia Bioven (Biopharma Plasma LLC) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) BIOPHARMA PLASMA LLC Ukraine 2020-05-07 2020-09-30 2020-BV-BP, NCT04500067 Phase 3 Clinical Recruiting 8 4 Months 76 Anatolii M Deyneka, MD, Andrii R Rybakov, MD, Igor P Bernik, MD, Iryna V Kobylyan, MD, Kateryna Yu Romanchuk, MD, Khrystyna V Lewandowska, MD, Larisa V Moroz, MD, Lilia Ya Romaniv, MD, Liliya B Kurilyak, MD, Ludmila K Boshkova, MD, Maryana V Gurkivska, MD, Mikhail G Kuzyuk, MD, Natalia B Zhevoronko, MD, Nataliya O Ivanchenko, MD, Oksana I Paraschuk, MD, Oksana M Mazur, MD, Oksana Ya Kadubets', MD, Oleg K Yakovenko, MD, Olena Ya Kobrynska, MD, Olga V Pronina, MD, Pavlo A Gashchishin, MD, Roman M Fishchuk, MD, Ruslan V Mazur, MD, Sergii L Zanozdra, MD, Sergii O Solyarik, MD, Svitlana Y Lavryukova, MD, Taisiya V Vzhetson, MD, Tamila I Aleksanyan, MD, Vasyil S Kopcha, MD, Prof., Viktor P Tokarev, MD, Vitalii A Lukiyanchuk, MD, Yaroslav G Zhebelenko, Ph.D., MD 2020-08-06
Clinical outcome and psychological impact Covid-19 Coronavirus disease 19 infection Hospital Sungai Buloh Malaysia 2020-08-05 2021-08-05 NMRR-20-1701-55822 Phase Not Applicable Not yet recruiting 1 12 Months Dr NORASHIKIN BT. ABDUL FUAD, Dr Syarifah Nurul Ain Bt Syed Badaruddin, Professor Dr Zaleha Abdullah Mahdy 2020-08-06
A trial of NTR-441 to treat hyperinflammation and thrombosis in COVID-19 patients, including those with Acute Respiratory Distress Syndrome (ARDS) Coronavirus disease 19 infection, Inflammatory disease, Respiratory distress syndrome, Thrombosis NTR-441 alone Deoxyribonuclease gamma stimulator Neutrolis Therapeutics Inc Phase Not Applicable Planned 0 2020-08-06
Mental Health Screening during COVID-19 Pandemic among School Teachers in Kerian District Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression, Psychiatric disorder QUEST INTERNATIONAL UNIVERSITY PERAK Malaysia 2020-10-01 2020-12-31 55999, NMRR-20-1700-55999 Phase Not Applicable Not yet recruiting 1 3 Months Tan Sing Ying 2020-08-06
DeSACCoS: Detection of SARS-CoV-2 Among Convalescent COVID-19 Patients Using Saliva Coronavirus disease 19 infection HOSPITAL SIBU Malaysia 2020-08-30 2021-08-31 DeSACCoS, NMRR-20-1684-56008 Phase Not Applicable Not yet recruiting 1 12 Months Dr Jeffrey Lee Soon Yit, Dr. Toh Teck Hock 2020-08-07
Impact of lockdown for COVID-19 pandemic towards glycemic control in paediatric diabetic patients Coronavirus disease 19 infection, Diabetes mellitus, Insulin dependent diabetes, Non-insulin dependent diabetes Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Putrajaya Hospital Malaysia 2020-08-17 2020-12-31 55949, NMRR-20-1678-55949 Phase Not Applicable Not yet recruiting 1 4 Months 80 Dr Cheng Hooi Peng 2020-08-07
Longitudinal COVID-19 Study Coronavirus disease 19 infection National Institutes of Health Malaysia Ministry of Health, Malaysia Malaysia 2020-08-17 2022-07-30 NMRR-20-1676-55108 Phase Not Applicable Recruiting 1 23 Months Dr MASITA BINTI ARIP, Dr Rafiza binti Shaharudin 2020-08-07
Longitudinal study of long-term immune response to SARS-CoV-2 in COVID-19 recovered patients Coronavirus disease 19 infection Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tropical Infectious Diseases Research & Education Centre Malaysia 2020-09-01 2022-08-31 NMRR-20-1669-55712 Phase Not Applicable Not yet recruiting 1 24 Months Prof. Sazaly Abu Bakar 2020-08-07
Sickness absence in NHS staff during the time of COVID-19 Coronavirus disease 19 infection, Psychiatric disorder electronic staff records alone Healthy volunteers accepted Imperial College London Colt Foundation UK 2020-08-01 2021-03-01 IRAS 284146, ISRCTN36352994 Phase Not Applicable No longer recruiting 0 7 Months 800000 Prof Paul Cullinan 2020-08-07
Identification of inflammation-related gene polymorphisms associated with the severity of COVID-19 Coronavirus disease 19 infection Tropical Infectious Diseases Research & Education Centre Malaysia 2020-09-01 2022-08-31 55710, NMRR-20-1668-55710 Phase Not Applicable Not yet recruiting 1 24 Months Prof. Sazaly Abu Bakar 2020-08-07
A Phase I trial of hAd5 S+N vaccine in healthy volunteers Coronavirus disease 19 infection recombinant bivalent second-generation adenovirus (hAd5) vector-delivered SARS-CoV-2 S + N protein vaccine (subcutaneous, COVID-19), ImmunityBio alone COVID19 Spike glycoprotein modulator, COVID19 nucleoprotein modulator Healthy volunteers accepted ImmunityBio Inc US Phase 1 Clinical Not yet recruiting 1 2020-08-06
IKN COVID-19 Task Force Strategies Coronavirus disease 19 infection National Cancer Institute - Malaysia Malaysia 2020-08-10 2021-02-19 NMRR-20-1665-56009 Phase Not Applicable Status not specified 1 6 Months Dr Sarah Pang Hui Li, Miss Siti Fatimah Zahra binti Mohd Anuar 2020-08-07
COVID-19 Sarawak Coronavirus disease 19 infection Sarawak General Hospital Malaysia 2020-08-03 2021-07-31 NMRR-20-1656-55896 Phase Not Applicable Not yet recruiting 1 11 Months Dr TONNII SIA LOONG LOONG 2020-08-07
Use of Herbal Medicine like Tulasi,Amruth(Giloy), Turmeric,Ashwagandha for Improving the Immunity among Health care workers Coronavirus disease 19 infection Variable regimens including Amruth tablet , Shakthi drops , TulsiArka , Turmeric Plus tablet Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Sriveda Sattva PvtLtd India 2020-08-15 CTRI/2020/08/027009 Phase 4 Clinical Not yet recruiting 1 100 Dr C R Jayanthi, Dr M Ravi Kumar Reddy 2020-08-06
STANCE: COVID-19 Pandemic: A situational analysis on clinic appointment system in the New Normal within the Malaysian Healthcare System Coronavirus disease 19 infection Clinical Research Malaysia Malaysia 2020-07-31 2020-12-31 55650, NMRR-20-1654-55650, STANCE Phase Not Applicable Not yet recruiting 1 5 Months Mr. HING YEE LIANG 2020-08-06
A clinical trial of humanized neutralizing nano-antibodies (nanobody-based technology, COVID-19), Beroni Group/Tianjin University for the potential treatment of COVID-19 infection Coronavirus disease 19 infection humanized neutralizing nano-antibodies (nanobody-based technology, COVID-19), Beroni Group/Tianjin University alone COVID19 Spike glycoprotein inhibitor Beroni Group Ltd Phase Not Applicable Planned 0 2020-08-06
Well-Being and Health-Related Quality of Life in Cancer Patients and Survivors During the COVID-19 Pandemic Anxiety disorder, Coronavirus disease 19 infection, Depression, Psychiatric disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) MD Anderson Cancer Center National Cancer Institute US 2020-06-11 2021-07-01 2020-0473, NCI-2020-04604, NCT04500600 Phase Not Applicable Recruiting 1 12 Months 50000 Lorenzo Cohen 2020-08-06
RCS-AYUSH: Retrospective cohort study in COVID-19 recovered patients Coronavirus disease 19 infection Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Council for Research in Homoeopathy India 2020-08-14 CTRI/2020/08/027000, RCS-AYUSH Phase Not Applicable Recruiting 1 5000 Dr Anil Khurana, Dr Anupriya, Dr Debadatta Nayak 2020-08-06
Advantage of Artificial Intelligence to detect COVID 19 using Chest X-Ray Coronavirus disease 19 infection Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Nirma University India 2020-08-17 CTRI/2020/08/027008 Phase Not Applicable Not yet recruiting 1 1000 Dr Asutosh N Dave 2020-08-06
An interventional study to access the effect of Ayurvedic medicine in positive cases of COVID-19 Coronavirus disease 19 infection SEM-20 alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ministry of Ayush India 2020-07-31 CTRI/2020/08/027007 Phase 3 Clinical Not yet recruiting 1 200 Dr Abhishek Bhattacharjee, Prof Dr P K Goswami 2020-08-06
Epidemiological Characteristics of 50 Patients of >/= 90 Years Hospitalized With COVID-19 Coronavirus disease 19 infection Elderly Adults (80 and over) Brugmann University Hospital Belgium 2020-06-09 2020-12-31 CHUB-COVID-19-90+, NCT04499300 Phase Not Applicable Recruiting 1 6 Months 50 Murielle Surquin, Sophie Levy, Tracy Vandergraesen, MD 2020-08-06
ZIMCOV: Investigation of effect of homoeopathic remedy as add on therapy to standard of care (regular treatment) in adult patients with moderate to severe COVID-19 Coronavirus disease 19 infection Zincum muriaticum alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Homoeocon Foundation India 2020-08-12 CTRI/2020/08/027005, ZIMCOV Phase 2 Clinical Not yet recruiting 1 96 Dr Anil Habbu, Dr Anil Khurana 2020-08-06
SIFRA-CBE: Evaluate the Efficacy of Siddha Treatment in Patients with Novel Coronavirus Infectious Disease (COVID-19) Coronavirus disease 19 infection Adathodai manapagu alone, Mahasudarsan chooranam alone, Maldevi chendooram alone, Nochi kudineer chooranam alone, Omatheeneeer alone, Siddha Medicine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Indian Medicine and Homoeopathy Government Medical College and ESI Hospital India 2020-08-10 CTRI/2020/08/026999, SIFRA-CBE Phase 2 Clinical Not yet recruiting 1 100 Dr Salai Karthikaiyan, Dr Shanmugam MD SIDDHA 2020-08-07
Association of cardiac markers with severity of covid 19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Postgraduate Institute of Medical Education and Research India 2020-08-20 CTRI/2020/08/027001 Phase Not Applicable Not yet recruiting 1 70 Sunder Lal Negi 2020-08-07
Study of changes in levels of certain blood parameters in covid-19 patients Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gujarat Cancer Society Medical college hospital and research centre India 2020-08-14 CTRI/2020/08/026981 Phase Not Applicable Not yet recruiting 1 1000 Dr Utsav Parmar 2020-08-06
Sofosbuvir + Ledipasvir and Nitazoxanide for Treatment of COVID-19 Coronavirus disease 19 infection, Respiratory disorder, Respiratory failure, Viral pneumonia nitazoxanide alone, sofosbuvir + ledipasvir alone, standard care alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Assiut University Helwan University Egypt 2020-07-15 2020-12-30 COVID-19 TREATMENT, NCT04498936 Phase 4 Clinical Recruiting 2 5 Months 240 Haidi K Ramadan, PhD, Mohamed El Kassas, PhD, Mohamed El kassas, Mohammed A Medhat, PhD, Mohammed Medhat 2020-08-06
Effect Ayurveda decoctions, tablet and Panchagavya on COVID 19 Coronavirus disease 19 infection Variable regimens including Fresh zinger juice , Gojihvadi Kwath , Sanjeevani Vati , honey Pancha Gavya Ghrit Granules , milk Shunthi (Dry Ginger powder) Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rashtriya Kamdhenu Aayog India 2020-08-10 CTRI/2020/08/026980 Phase 3 Clinical Not yet recruiting 1 180 Parameswarappa Byadgi 2020-08-07
An FDA compassionate use program of PSC-04 (Calidi Biotherapeutics Inc)for the treatment of covid-19 Coronavirus disease 19 infection PSC-04 (Calidi Biotherapeutics Inc) alone Calidi Biotherapeutics Inc, Personalized Stem Cells Inc Phase Not Applicable Planned 0 2020-08-06
A Phase II clinical trial of PSC-04 (Calidi Biotherapeutics Inc)for the treatment of covid-19 Coronavirus disease 19 infection PSC-04 (Calidi Biotherapeutics Inc) alone Calidi Biotherapeutics Inc, Personalized Stem Cells Inc Phase 2 Clinical Planned 0 2020-08-06
The MINDS study: Youth experiences during COVID-19 pandemic Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs) Melaka Manipal Medical College, India India 2020-08-14 CTRI/2020/08/026998, The MINDS study Phase Not Applicable Not yet recruiting 1 540 Varalakshmi Chandra Sekaran 2020-08-06
TIP: Talking in primary care: testing the impact of online training in empathy and optimism for healthcare professionals Coronavirus disease 19 infection, Osteoarthritis continue normal practice alone, online training alone Healthy volunteers accepted University Of Southampton National Institute for Health Research (NIHR) UK 2019-12-02 2021-03-31 CPMS 43793, ISRCTN21215037, TIP Phase Not Applicable Recruiting 1 15 Months 280 Dr Felicity Bishop, Mrs Broomfield 2020-08-07
GERAS Frailty Rehabilitation at Home During COVID-19 Coronavirus disease 19 infection Medication Review alone, Senior Isolation Prevention Partnership (SSIPP) program alone, multi-modal frailty rehabilitation alone, physiotherapy alone, protein supplement (protein + beta-hydroxy beta-methylbutyrate) alone, virtual nutrition consult alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) McMaster University Canada 2020-09-30 2021-05-31 11408, NCT04500366 Phase Not Applicable Not yet recruiting 1 8 Months 70 Alexandra Papaioannou, MD, MSc, Sherri Smith 2020-08-06
Assessment of safety and efficacy of Kabasura kudineer in mild to moderate COVID-19 Coronavirus disease 19 infection Kabasura kudineer alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Chettinad Hospital And Research Institute India 2020-08-14 CTRI/2020/08/026985 Phase 2 Clinical Not yet recruiting 1 126 Dr Ruckmani A, Dr Vivek Valliappan 2020-08-06
Effectiveness of Ayurvedic Formulation for COVID 19 Coronavirus disease 19 infection YASH-T decoction alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Nepal Health Research Council India 2020-08-19 CTRI/2020/08/026978 Phase Not Applicable Not yet recruiting 1 100 Dr Pradip Gyanwali, Shristi Karki 2020-08-07
OPTYC: Online post-traumatic stress disorder treatment for young people and their carers Coronavirus disease 19 infection, Post traumatic stress disorder Internet-delivered Cognitive Therapy alone Children (6-12 yrs), Adolescents (13-17 yrs) South London and Maudsley NHS Foundation Trust Medical Research Council UK 2017-12-01 2022-02-26 IRAS 262807, CPMS 42768, ISRCTN16876240, OPTYC Phase Not Applicable Recruiting 4 50 Months 34 Dr Smith 2020-08-06
Comparison of two online learning method of resuscitation training Cardiac arrest, Coronavirus disease 19 infection Flexible online learning alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) All India Institute of Medical Sciences India 2020-08-10 CTRI/2020/08/026977 Phase Not Applicable Not yet recruiting 1 20 Poonam Joshi 2020-08-07
OTC AND COVID19: Over-the-counter Medications And COVID-19 Coronavirus disease 19 infection University of Alberta Canada 2020-07-23 2023-03-31 NCT04500639, OTC AND COVID19, PRO00100243 Phase Not Applicable Recruiting 1 32 Months 14000 Scot H Simpson, PharmD, MSc, Scot Simpson, PharmD, MSc 2020-08-07
Evaluation of coronavirus self-isolation interventions Coronavirus disease 19 infection Call only alone, SMS only alone, SMS plus call alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Health Service Department of Health and Social Care UK 2020-07-01 2020-09-30 ISRCTN13455972, TP_2020065 Phase Not Applicable Recruiting 1 3 Months 10000 Ms Clare Delargy, Ms Hannah Burd 2020-08-07
An observational study of effect of positioning on either side on oxygen level in corona patient Coronavirus disease 19 infection lateral positioning alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) New Civil Hospital, Surat India 2020-08-09 CTRI/2020/08/026964 Phase Not Applicable Not yet recruiting 1 167 Dr Sunaina patel 2020-08-07
POCUS: Point of care ultrasound study in patients with respiratory illness during COVID-19 Coronavirus disease 19 infection, Respiratory tract infection Lung ultrasound alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kasturba Medical College and Hospital India 2020-08-17 CTRI/2020/08/026983, POCUS Phase Not Applicable Not yet recruiting 1 100 Dr Sanjan 2020-08-07
Tomographic Findings in COVID-19 and Influenza H1N1 Coronavirus disease 19 infection, Influenza virus A infection, Viral pneumonia pulmonary tomography alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidad De Guanajuato University Medical Center Groningen Netherlands, Mexico 2020-08-15 2022-04-30 F-2020-1008-038, NCT04499378 Phase Not Applicable Not yet recruiting 2 20 Months 200 Jaime D Mondragon, M.D., Omar Jiménez-Zarazúa, M.D. 2020-08-06
Dexamethasone Versus Methylprednisolone for the Treatment of Patients With ARDS Caused by COVID-19 Adult respiratory distress syndrome, Coronavirus disease 19 infection dexamethasone alone, methylprednisolone alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chattogram General Hospital Xi' An Medical University Bangladesh 2020-08-02 2020-11-30 10000753, NCT04499313 Phase 3 Clinical Recruiting 2 3 Months 60 Abu Taiub Mohammed Mohiuddin Chowdhury, MBBS, MD, Ahter Kamal, MBBS, MD, PhD, Akter Kamal, MBBS, MD, PhD, Shubhashis Talukder, Shubhashis Talukder, MBBS, DO 2020-08-07
Incubation period of COVID-19 cases admitted in North Kerala, India Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Government Medical College Kannur India 2020-09-01 CTRI/2020/08/026962 Phase Not Applicable Not yet recruiting 1 30 Anitha S S 2020-08-07
MtS Dems: HF4Y: Research demonstration projects in youth homelessness Coronavirus disease 19 infection Housing First For Youth alone Adolescents (13-17 yrs), Young Adults (18-44 yrs) A Way Home Canada Employment Skills Development Canada Canada 2017-08-01 2021-03-31 1441994, ISRCTN10505930, MtS Dems: HF4Y Phase Not Applicable No longer recruiting 2 44 Months 140 Dr Stephen Gaetz, Ms MacDonald 2020-08-06
Evaluation of Knowledge, Attitude and Practice (KAP) of Pharmacists towards novel coronavirus pneumonia (COVID-19): A Cross-Sectional Study Coronavirus disease 19 infection Online questionnaire alone Peking University Third Hospital China 2020-07-23 2021-07-22 ChiCTR2000035213 Phase Not Applicable Not yet recruiting 1 12 Months 480 Rongsheng ZHAO, Zaiwei SONG 2020-08-06
Mental Health Status and Related Factors Among Physical Medicine And Rehabilitation Physicians in the COVID-19 Pandemic Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression, Insomnia Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dokuz Eylul University Turkey 2020-06-27 2020-10-01 NCT04500652, PMRMENTALCOVID Phase Not Applicable Recruiting 1 3 Months 310 Banu Dilek 2020-08-07
Multicenter, Randomized, Controlled Trial of Hyperbaric Versus Normobaric Oxygen Therapy for COVID-19 Patients Coronavirus disease 19 infection, Viral pneumonia hyperbaric oxygen alone, usual treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ottawa Hospital Research Institute Climate Foundation Canada 2020-08-31 2022-08-31 NCT04500626, OHRI-HBOT-001 Phase 2/Phase 3 Clinical Not yet recruiting 1 24 Months 234 Joseph Burns, MSc, Sylvain Boet, MD, PhD 2020-08-07
Evaluation of herbal compound containing Anacyclus pyrethrum, Senna, Ferrula asafoetida and Terminalia chebula in COVID19 Coronavirus disease 19 infection Variable regimens including Anacyclus pyrethrum , Chloroquine phosphate , Ferrula asafoetida , Hydroxychloroquine , Senna , Terminalia chebula Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tabriz University of Medical Sciences Iran 2020-07-31 2020-09-21 IR.TBZMED.REC.1399.126, IRCT20200522047545N1 Phase 2/Phase 3 Clinical Recruiting 1 1 Month 200 Mojtaba Varshouchi Fard, Ramin Mohammadzadeh 2020-08-06
A Study on Prevalence, Protection and Recovery From COVID-19 in Seasoned Yoga Practitioners in Comparison to Age and Gender Matched Controls Acute stress disorder, Coronavirus disease 19 infection, Fever, Respiratory disease Inner Engineering Completion (Shambhavi Mahamudra kriya) alone, Inner Engineering Online alone, Shakthi Chalana Kriya alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Beth Israel Deaconess Medical Center US 2020-05-22 2020-12-31 2020P000433, NCT04498442 Phase Not Applicable Recruiting 1 7 Months 30000 Balachundhar Subramaniam, MD, MPH 2020-08-07
To Evaluate Safety and Efficacy of EC-18 in COVID-19 Infection to Pneumonia Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia mosedipimod alone CCL26 gene inhibitor, TLR modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Enzychem Lifesciences Corp South Korea 2020-05-28 2022-05-31 EC-18-C201, NCT04500132 Phase 2 Clinical Recruiting 1 24 Months 60 Enzychem Lifescience, Hyewon Jeong 2020-08-06
A phase III trial to evaluate Metablok for the prevention of organ inflammation known to trigger acute respiratory distress syndrome (ARDS) and acute kidney injury (AKI) in patients infected with SARS-CoV-2 (COVID-19) Coronavirus disease 19 infection, Inflammatory disease, Renal injury, Respiratory distress syndrome Metablok alone Dehydropeptidase-1 modulator Arch Biopartners Inc Phase 3 Clinical Planned 0 2020-08-06
COVEN: Mechanical Ventilation Strategy for Coronavirus Disease 2019 (COVID-19) Coronavirus disease 19 infection, Lung injury, Respiratory distress syndrome electrical impedance tomography alone, pressure-controlled ventilation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo InCor Heart Institute Brazil 2020-05-08 2021-12-01 CAAE: 30938720800000068, COVEN, NCT04497454 Phase Not Applicable Recruiting 1 18 Months 128 Eduardo LV Costa, Eduardo LV Costa, PhD, Maria AM Nakamura, Maria AM Nakamura, PhD 2020-08-07
Novel Coronavirus infection among health workers Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) State of Parana/Health Department of Parana Brazil 2020-07-01 2021-07-01 33697720.0.0000.0107, 4,112,388, RBR-7nky44, U1111-1255-6093 Phase Not Applicable Recruiting 1 12 Months 703 Lirane Elize Ferreto 2020-08-06
A phase III human trial of Oxford vaccine by serum institute of India Coronavirus disease 19 infection Oxford vaccine alone Serum Institute of India Ltd India Phase 3 Clinical Planned 1 1600 2020-08-06
A phase II trial in India for the covid-19 vaccine candidate developed by University of Oxford Coronavirus disease 19 infection Oxford vaccine alone Healthy volunteers accepted Serum Institute of India Ltd India Phase 2 Clinical Planned 1 1600 2020-08-06
Pilot Study of Video and Telephone Primary Care Visits Coronavirus disease 19 infection Telemedicine-Internet-connected computer tablet alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Johns Hopkins University US 2020-08-01 2023-02-01 IRB00257994, NCT04496713 Phase Not Applicable Not yet recruiting 1 30 Months 200 Casey Overby Taylor, PhD, Jeremy A Epstein, MD 2020-08-06
The Effect of Aromatherapy on COVID-19-induced Anxiety Anxiety disorder, Coronavirus disease 19 infection Essential Oil Blend inhalation alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Franklin School of Integrative Health Sciences US 2020-08-01 2021-04-30 20-7-5600, NCT04495842 Phase Not Applicable Not yet recruiting 1 9 Months 65 Jessie Hawkins, PhD, PI 2020-08-06
Augmented CBGT for Perinatal Anxiety During a Global Pandemic (COVID-19) Anxiety disorder, Coronavirus disease 19 infection Cognitive Behavioural Group Therapy alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) St Josephs Healthcare Hamilton 2020-08-10 2022-08-01 CBT-COVID, NCT04495803 Phase Not Applicable Not yet recruiting 0 23 Months 120 Sheryl Green, PhD, CPsych 2020-08-06
Mitigating Suicide Risk With Single Session 'Brief Skills for Safer Living' Coronavirus disease 19 infection, Suicide Brief Skills for Safer Living alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) St Michaels Hospital Canada 2020-08-31 2021-08-31 BSL-01, NCT04495543 Phase Not Applicable Not yet recruiting 1 12 Months 75 Aleksandra Lalovic, PhD, Michael Morton, HBSc, Sakina Rizvi, PhD, Sidney H Kennedy, MD, Yvonne Bergmans, PhD 2020-08-06
Co_Coping: Coping With 2020 - No Health Without Mental Health Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Psychiatric disorder Intensive Co-mestring alone, Ordinary Co-mestring alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Haukeland University Hospital Norway 2020-04-02 2021-12-31 126376, Co_Coping, NCT04421612 Phase Not Applicable Recruiting 1 20 Months 400 Tine Nordgreen, PhD 2020-08-06
The COVID-19 and Healthcare Workers: An Active Intervention Anxiety disorder, Coronavirus disease 19 infection, Depression, Phobia, Post traumatic stress disorder Video-Based intervention alone, written description alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Research Foundation for Mental Hygiene Inc US 2020-07-30 2021-01-30 8032, NCT04497415 Phase Not Applicable Not yet recruiting 1 6 Months 1200 Doron Amsalem, MD, Yuval Neria, PhD 2020-08-06
SignCov: Assesment of the Metabolomic Signature in COVID-19 Patients Coronavirus disease 19 infection blood and urine sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire De Nice France 2020-08-07 2021-10-07 20-PP-18, NCT04497272, SignCov Phase Not Applicable Not yet recruiting 1 14 Months 150 OCCELLI Céline, OCELLI Celine 2020-08-06
Comparison of the Effectiveness of Compassionate Therapy and Positive Psychology with Well-being Approach on Alexithymia, Adaptive Behavior, Adherence of Treatment and Biological Factors in Patients with Diabetes Type 2 Coronavirus disease 19 infection, Non-insulin dependent diabetes, Psychiatric disorder Compassionate Therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Islamic Azad University Iran 2020-05-21 IR.HUMS.REC.1399.105, IRCT20191023045222N1 Phase Not Applicable No longer recruiting 1 100 Dr. Leila Moradi, Mahnaz Bahadori, Mahnaz Mehrabizadeh Honarmand 2020-08-06
Study of F-652 (IL-22:IgG2 Fusion Protein) in Patients With Moderate to Severe COVID-19 Coronavirus disease 19 infection F-652 alone IL-22 agonist, Interleukin 22 ligand Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Evive Biotech US 2020-08-10 2021-02-28 GC-652-04, NCT04498377 Phase 2 Clinical Not yet recruiting 1 6 Months 38 Christine M Bojanowski, MD, William L Daley, MD 2020-08-06
BLAZE-2: A Study of LY-3819253 in Preventing SARS-CoV-2 Infection and COVID-19 in Nursing Home Residents and Staff Coronavirus disease 19 infection LY-CoV555 alone COVID19 Spike glycoprotein modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Eli Lilly & Co AbCellera Biologics Inc, National Institute of Allergy and Infectious Diseases US 2020-08-01 2021-06-29 18063, BLAZE-2, COVPN #3501, J2X-MC-PYAD, NCT04497987 Phase 3 Clinical Recruiting 101 10 Months 2400 C Hall, C Thai, Carl Fichtenbaum, Christine Thai, Christopher Hall, David Wohl, G Taffet, George Taffet, Ian Frank, S Doblecki-Lewis, S Edupuganti, S Mayer, Srilatha Edupuganti, Stockton Mayer, Sue Ellen Abdalian 2020-08-06
COVID-19-Positive Outpatient Thrombosis Prevention in Adults Aged 40 to 79 Coronavirus disease 19 infection, Inflammatory disease, Thrombosis apixaban alone, aspirin alone Factor Xa antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Pittsburgh National Heart Lung and Blood Institute US 2020-08-31 2021-03-31 ACTIV4-OUTPATIENT, NCT04498273 Phase 3 Clinical Not yet recruiting 1 7 Months 7000 Frank Sciurba, Jean Connors, Paul Ridker, M.D. 2020-08-06
CoCo-20: A Longitudinal Follow-up Study of the French Pediatric Population During and After the Coronavirus Pandemic Coronavirus disease 19 infection, Post traumatic stress disorder, Psychiatric disorder emergency semi-directed interview alone, mental health assessment alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) Fondation Lenval France 2020-04-27 2020-12-31 20-HPNCL-05, CoCo-20, NCT04498416 Phase Not Applicable Recruiting 1 8 Months 70 Arnaud FERNANDEZ, MD, Arnaud Fernandez, Aurélien Richez, Florence Gittard-Askenazy, Pr, Michèle Battista, Morgane GINDT, Morgane Gindt, Ophélie Nachon 2020-08-05
Evaluating the Effect of NT-I7, a Long Acting Interleukin-7, to Increase Lymphocyte Counts and Enhance Immune Clearance of SARS-CoV-2 (COVID-19) Coronavirus disease 19 infection NT-17 alone, Standard of care treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Washington University School of Medicine, US NeoImmuneTech Inc US 2020-09-30 2021-06-30 06-29-20-CAMPIAN, NCT04498325 Phase 1 Clinical Not yet recruiting 1 9 Months 42 Alexandre Lacasse, M.D., Erik R Dubberke, M.D., MSPH, Jian Campian, M.D., Ph.D., Mary McLennan, M.D. 2020-08-06
Psychological Impact, Mental Health and Sleep Disorder Among Patients Hospitalized and Health Care Workers During the 2019 Coronavirus Outbreak (COVID-19) Coronavirus disease 19 infection, Psychiatric disorder, Sleep disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Brugmann University Hospital Belgium 2020-05-29 2020-12-31 CHU-COVIDIMPACT, NCT04497246 Phase Not Applicable Recruiting 1 7 Months 5000 Maxime Windal, Murielle Surquin, Head of geriatry department, Sophie Levy, Sophie Levy, MD 2020-08-06
Psychosocial Outcomes in Families of COVID-19 ICU Patients Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Liege Belgium 2020-04-16 2020-09-30 FAMILY COVID, NCT04498507 Phase Not Applicable Recruiting 1 5 Months 50 Anne-Françoise Rousseau, MD, PhD, Anne-Françoise Rousseau, PhD, Rousseau, MD, PhD 2020-08-06
Mask Usage and Exercise During the COVİD-19 Pandemic Coronavirus disease 19 infection, Dyspnea, Fatigue Exercise tests alone, Surgical mask alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) KTO Karatay University Turkey 2020-07-20 2021-09-30 KARATAYU3, NCT04498546 Phase Not Applicable Recruiting 1 14 Months 60 Büşra Alkan, MsC, PT, RA, Büşra Alkan, MsC, Pt, RA, Büşra Alkan, Research Assistant, Sevgi Özalevli, Prof, PT, Özlem Akkoyun Sert, Phd, PT 2020-08-07
TOMOCOVIDMX: Tomographic Findings in COVID-19 and Influenza Coronavirus disease 19 infection, Influenza virus A infection, Viral pneumonia pulmonary tomography alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidad De Guanajuato Hospital General Regional de León, University Medical Center Groningen Mexico 2020-06-15 2022-04-30 HGL-ENSE-00743-20, NCT04497311, TOMOCOVIDMX Phase Not Applicable Recruiting 1 22 Months 100 Jaime Daniel Mondragón Uribe, Medical researcher, Lourdes N Veléz-Ramírez, M.D., Lourdes N Vélez-Ramírez, M.D., Omar Jiménez-Zarazúa, M.D. 2020-08-06
Sofosbuvir Containing Regimens in Treatment of COVID 19 Patients Coronavirus disease 19 infection sofosbuvir + ledipasvir (fixed-combination/oral, HCV/HBV), Gilead alone, standard of care treatment alone, Variable regimens including daclatasvir , ribavirin , sofosbuvir Hepatitis C virus NS5B polymerase inhibitor, Hepatitis C virus protein NS5A inhibitor Tanta University Egypt 2020-07-01 2030-12-10 NCT04497649, TANTA SOFOSBUVIR COVID Phase 2/Phase 3 Clinical Recruiting 1 125 Months 200 Marwa Salama, Lecturer, Sherief Abd-Elsalam, ass. prof., sherief Abd-Elsalam, ass. Prof., sherief abd-elsalam, ass. prof, sherief abd-elsalan, ass. prof. 2020-08-05
A Study to Assess Safety, Tolerability, and Immunogenicity of V-591 (COVID-19 Vaccine) in Healthy Participants Coronavirus disease 19 infection MERS-Corona virus vaccine (recombinant live-attenuated measles virus vector), Themis alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Merck Sharp & Dohme Corp 2020-08-19 2022-03-16 2020-003493-46, NCT04498247, V591-001 Phase 1/Phase 2 Clinical Not yet recruiting 0 18 Months 260 Medical Director 2020-08-07
Changes in Out-patient Visits in Taiwan During the Time of Global COVID-19 Pandemic Coronavirus disease 19 infection National Taiwan University Hospital Taiwan 2020-08-01 2020-12-31 202006225RINA, NCT04497467 Phase Not Applicable Recruiting 1 5 Months 1200000 Wan-Ching Lien, Wan-Ching Lien, PhD 2020-08-06
Clinical trial for the treatment of COVID-19 with Chloroquine and Colchicine Coronavirus disease 19 infection chloroquine plus colchicine Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital das Clinicas de Ribeirao Preto/USP Conselho Nacional de Desenvolvimento Cientifico e Tecnologico - CNPq, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Fundacao de Amparo a Pesquisa do Estado Sao Paulo 2020-04-11 2020-09-30 3.954.378, 30248420.9.0000.5440, 30248420.9.0000.5440, 30248420.9.3001.5403, 4.066.630, 4.112.255, RBR-8jyhxh, U1111-1255-6304 Phase 2/Phase 3 Clinical Recruiting 0 5 Months 60 Renê D. Ribeiro Oliveira 2020-08-06
Educational intervention by cell phone to increase informed choices at childbirth, in the context of the Covid-19 pandemic Coronavirus disease 19 infection, Pregnancy disorder PiniOn alone, educational communication intervention alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Sociedade Beneficente Israelita Brasileira Hospital Albert Einsten, University of Sao Paulo Brazil 2020-08-28 32840920.7.0000.0071, 4.132.178, RBR-3g5f9f, U1111-1255-8683 Phase Not Applicable Not yet recruiting 1 20000 Carmen Simone Grilo Diniz, Edson Amaro Junior, Livia Sanches Pedrilio 2020-08-06
STRING-COVID: Mental Health Impact of the COVID-19 Pandemic Among Migrants in Chile Coronavirus disease 19 infection, Psychiatric disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Pontificia Universidad Catolica De Chile Chilean Science Council Chile 2020-07-03 2021-01-31 170519004, NCT04497636, STRING-COVID Phase Not Applicable Recruiting 1 6 Months 1092 Antonia Errazuriz, PhD 2020-08-07
Safety and Feasibility of Amniotic Fluid as a Treatment for COVID-19 Patients Coronavirus disease 19 infection, Inflammatory disease acellular sterile filtered human amniotic fluid alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Utah US 2020-08-15 2021-08-15 132922, NCT04497389 Phase 1/Phase 2 Clinical Not yet recruiting 1 12 Months 60 Alyssa Messina, MA, Craig Selzman, MD 2020-08-07
Acalabrutinib Study With Best Supportive Care in Participants Hospitalized With COVID-19 Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia Nasogastric tube alone, Proton pump inhibitor therapy alone, acalabrutinib alone Btk tyrosine kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) AstraZeneca plc Acerta Pharma BV US 2020-07-31 2020-09-28 D822FC00005, NCT04497948 Phase 1 Clinical Not yet recruiting 3 1 Month 20 AstraZeneca Clinical Study Information Center 2020-08-07
Evaluation of the effectiveness of Cyclotide complex herbal syrup in preventing COVID-19 virus in exposed individuals Coronavirus disease 19 infection Variable regimens including Pimpinela anisum hydroalcoholic extract , Ziziphus spina-cristi , cyclopeptide fraction , orange peel Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Bagheiat-allah University of Medical Sciences Iran 2020-04-20 IR.BMSU.REC.1399.250, IRCT20160131026298N4 Phase 2/Phase 3 Clinical Recruiting 1 60 AHMAD REZA SHARIFI OLOUNABADI, Gholamhosein Alishiri, Shiva Shamshiri, shiva shamshiri 2020-08-05
Effect of Corton on olfactory dysfunction in COVID-19 patients Coronavirus disease 19 infection, Dysomia mometasone alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Mashhad University of Medical Sciences Iran 2020-07-18 IR.MUMS.REC.1399.355, IRCT20200522047542N1 Phase 1 Clinical Recruiting 1 70 Masoumeh Hosseinpour 2020-08-07
COMS-19: COVID-19 and SARS-CoV-2 Antibodies in Multiple Sclerosis Patients Coronavirus disease 19 infection, Multiple sclerosis Sars-CoV-2 RBD total antibody test (Sanquin) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) VU University Medical Center Netherlands 2020-08-06 2021-12-01 COMS-19, NCT04498286, NL74243.029.20 Phase Not Applicable Recruiting 1 15 Months 800 Joep Killestein, Zoé L van Kempen 2020-08-05
COVID-HEART study: COVID-19 effects on the heart Coronavirus disease 19 infection, Heart disease Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Leeds UK 2020-04-16 2022-07-31 CD20/133244, IRAS 285147, COVID-HEART study, ISRCTN58667920 Phase Not Applicable Recruiting 18 27 Months 370 Dr Laura Jones (public),, Kathryn Somers (public), Prof Greenwood 2020-08-05
SabanaHerons: Clinical Evaluation of Ventilador Innovation Product in Colombia in the SARS COVID 19 Pandemic, Unisabana Herons Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure, Traumatic brain injury Unisabana-Herons ventilator alone, Volume-controlled mechanical ventilation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Fundación Neumologica Colombiana Clínica Universidad de La Sabana, Fundación Cardioinfantil-Instituto De Cardiología, Universidad de la Sabana Colombia 2020-07-28 2020-12-31 202006-25502, NCT04497623, SabanaHerons Phase 1 Clinical Not yet recruiting 3 5 Months 5 Alirio R Bastidas, MD, MSc, Fabio A Varon-Vega, MD, PhD(c), Luis F Giraldo-Cadavid, MD, PhD 2020-08-07
DOMY COVID: Myocardial Damages Related to COVID-19 Coronavirus disease 19 infection, Heart injury, Myocarditis Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire Dijon France 2020-03-01 2021-07-31 COTTIN AOIC 2020, DOMY COVID, NCT04498065 Phase Not Applicable No longer recruiting 1 17 Months 200 2020-08-07
An Epidemiological Investigation on Correct Wearing of Mask by Direct Spray Test Coronavirus disease 19 infection, Respiratory disease FT-30 qualitative fitness test system (3M) alone, mask wearing alone, spray test alone Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cardiovascular Institute and Fuwai Hospital China 2020-06-19 2020-08-31 2020-KZLXB-02-01, NCT04497675 Phase Not Applicable Recruiting 8 2 Months 10000 Bin Wen, Duo lin, Lin C Duo, Lin Duo, Lin H Duo, Pengxu H Kong, Rundi Deng, Xiang-Bin Pan 2020-08-07
EPI CV COVID: Epidemiological Approaches to the Cardiovascular Consequences of COVID-19 Coronavirus disease 19 infection, Myocardial infarction, Respiratory failure, Sepsis, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire Dijon France 2020-03-15 2021-07-31 EPI CV COVID, NCT04498091, ZELLER AOIC 2020 Phase Not Applicable No longer recruiting 1 16 Months 35 2020-08-05
G-COV: Sex-Informed Data in the COVID-19 Pandemic Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universita degli Studi di Roma La Sapienza Italy 2020-09-01 2022-06-01 G-COV, NCT04497402, SAPIENZAGENDERCOVID Phase Not Applicable Not yet recruiting 1 21 Months 88 Claudio Mastroianni, MD, Guido Antonelli, MD, Lucia Stefanini, PhD, Marcella Visentini, MD, Maria Ciardi, MD, Roberto Cangemi, MD, Stefania Basili, Stefania Basili, MD, Stefano Corradini, MD, Valeria Raparelli, MD 2020-08-07
An Epidemiological Investigation on Correct Wearing of Mask by Hood Test Coronavirus disease 19 infection, Respiratory disease FT-30 qualitative fitness test system (3M company) alone, breathing test alone, fitness test spray reagent alone, hood wearing test alone, sensitivity test alone, suitability testing alone Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cardiovascular Institute and Fuwai Hospital China 2020-06-19 2020-08-31 2020-KZLXB-02-02, NCT04497753 Phase Not Applicable Recruiting 8 2 Months 10000 Bin Wen, Duo H lin, Lin Duo, Pengxu Kong, Rundi Deng, Xiang-Bin Pan 2020-08-07
A randomized, double-blind trial to determine whether convalescent blood plasma therapy can effectively be used for the prevention of people who have been exposed to COVID-19 in their home or at work as health care providers Coronavirus disease 19 infection convalescent blood plasma therapy alone Johns Hopkins Technology Ventures US Department of Defense Phase Not Applicable Status not specified 0 500 2020-08-05
ECHO-vid: Stress Echocardiography in Patients Recovery From Mild COVID-19 Illness Coronavirus disease 19 infection echocardiography alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Hospital Beneficencia Espanola de Puebla Mexico 2020-09-01 2020-11-30 CARDIOLOGY-004, ECHO-vid, NCT04498299 Phase Not Applicable Recruiting 1 3 Months 30 Consuelo Orihuela Sandoval, Jaime Hernandez-Montfort, Miguel Ayala León, Cardiolology, Miguel Ayala-Leon, Rosa Tzompantzi-Flores, Victoria Delgado, miguel ayala-leon 2020-08-07
A randomized, double-blind trial to determine whether convalescent blood plasma therapy can effectively be used to treat people in the early stage of COVID-19 illness Coronavirus disease 19 infection convalescent blood plasma therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Johns Hopkins Technology Ventures US Department of Defense Phase Not Applicable Status not specified 0 600 2020-08-05
Registry of COVID-19 Patients at AOUI Verona Coronavirus disease 19 infection Azienda Ospedaliera Universitaria Integrata Di Verona Italy 2020-03-01 2020-09-30 COVID19-VR, NCT04497194 Phase Not Applicable Recruiting 1 7 Months 500 Evelina Tacconelli, Evelina Tacconelli, Professor 2020-08-05
SARS-CoV-2 (COVID-19) Detection Using the Breath Analyzer TeraSystem Coronavirus disease 19 infection breath detector analyzer (TeraSystem) alone, rapid detection breath test alone Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto Costarricense de Investigaciones Clínicas ICIC Costa Rica 2020-08-04 2020-08-15 NCT04497610, TERA-CR-1 Phase Not Applicable Not yet recruiting 1 1000 Dr. Guillermo Rodríguez Gómez, Guillermo Rodríguez Gomez, MD 2020-08-05
Virtual White Boards for Patient Satisfaction Coronavirus disease 19 infection virtual display screen (e-ink screen) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Brigham & Women's Hospital E Ink Corp US 2020-08-20 2021-04-17 2020P002382, NCT04497922 Phase Not Applicable Not yet recruiting 1 7 Months 100 Guruprasad D Jambaulikar, MBBS MPH, Peter R Chai, MD, Peter R Chai, MD MMS 2020-08-07
Analysis of Coronavirus Disease 19 (COVID-19) Convalescent Plasma Coronavirus disease 19 infection convalescent plasma alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) City of Hope Medical Center National Cancer Institute US 2020-08-21 2022-08-21 20204, NCI-2020-04000, NCT04497779, P30CA033572 Phase Not Applicable Not yet recruiting 1 24 Months 800 John Zaia 2020-08-05
Netizens' Perception of COVID-19 Information and Information Sources Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Qassim University Saudi Arabia 2020-06-10 2020-08-15 NCT04497441, QASSIMU3 Phase Not Applicable Recruiting 1 2 Months 385 Bugude Shiva Shankar, MDS, Shiva Shankar Bugude, MDS 2020-08-07
Correlation Fear of COVID-19 and Dental Treatment Anxiety Anxiety disorder, Coronavirus disease 19 infection, Tooth disease Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Qassim University Saudi Arabia 2020-06-16 2020-07-25 NCT04497818, QASSIMU2 Phase Not Applicable Completed 1 1 Month 385 Bugude Shiva Shankar 2020-08-07
An observational study of the treatment of patients with mild and moderate COVID-19 (including suspected patients) Coronavirus disease 19 infection Kampo medicine alone, Western medicine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tohoku University Hospital Japan 2020-07-04 UMIN000041301 Phase Not Applicable Recruiting 1 1000 Akiko Kuwabara, Shin Takayama 2020-08-07
Local Tolerability and Pharmacokinetic Evaluation of Cyclops Dry Powder Hydroxychloroquine Inhalation in Healthy Volunteers Coronavirus disease 19 infection hydroxychloroquine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University Medical Center Groningen Netherlands 2020-09-15 2020-11-15 CARRIED-01, NCT04497519 Phase 1 Clinical Recruiting 1 2 Months 12 Onno Akkerman, Onno Akkerman, MD 2020-08-07
COVID-19-101: A Randomized, Placebo-controlled Trial to Evaluate the Safety and Immunogenicitiy of the COVID-19 Vaccine Coronavirus disease 19 infection COVID-19 vaccine (measles vaccine vector technology), Institut Pasteur/Themis Bioscience/University of Pittsburgh alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Institut Pasteur, Themis Bioscience GmbH, University of Pittsburgh ABL Europe, Coalition for Epidemic Preparedness Innovations Belgium, France 2020-08-31 2021-10-31 2020-002973-89, 2020-016, COVID-19-101, NCT04497298 Phase 1 Clinical Not yet recruiting 2 14 Months 90 Christiane GERKE, PhD, Cécile ARTAUD, Mohand AIT AHMED, Odile LAUNAY, MD, PhD, Robin ROGIERS, MD 2020-08-07
A study to assess OraSure’s OMNIgene oral device for SARS-CoV-2 Saliva Test Coronavirus disease 19 infection OMNIgene alone OraSure Technologies Inc Phase Not Applicable Status not specified 0 2020-08-06
Evaluate the efficacy of hydroxychloroquine in the prevention of SARS-COV2 infection in high risk health care workers Coronavirus disease 19 infection hydroxychloroquine alone Isfahan University of medical Sciences Iran 2020-04-18 IR.MUI.MED.REC.1399.0.17, IRCT20200414047076N1 Phase 2 Clinical Recruiting 2 160 Elahe Nasri, elahe Nasri 2020-08-07
CCPSEI: Clinical Characterization Protocol for Severe Infectious Diseases Coronavirus disease 19 infection, Respiratory tract infection sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Johns Hopkins University US 2020-04-09 2021-06-30 CCPSEI, IRB00245545, NCT04496466 Phase Not Applicable Recruiting 1 14 Months 500 Lauren Sauer, MS 2020-08-07
CO-FRAIL: Frailty and adverse outcomes in adults hospitalized for COVID-19 Cognitive disorder, Coronavirus disease 19 infection, Respiratory distress syndrome Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo Brazil 2020-03-30 32037120.6.0000.0068, 4.050.650, CO-FRAIL, RBR-7w5zhr, U1111-1252-9993 Phase Not Applicable Recruiting 1 2000 Márlon Juliano Romero Aliberti, Thiago Junqueira Avelino-Silva 2020-08-06
Physical and Psychological Impact of the COVID-19 Pandemic in Germany- a Survey of General Practitioners Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sauerlandpraxis Medebach, Hallenberg, Winterberg Germany 2020-08-10 2020-449-f-S, DRKS00022157 Phase Not Applicable Not yet recruiting 1 500 Simon Wernhart 2020-08-06
PraeCoSa: Precalence study on ICU Treatment of COVID-19 patients in Northern and Western Saxony in the first half of 2020 - PraeCoSa Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) UniversitätsKlinikum Leipzig Deutsche Forschungsgemeinschaft (DFG) Germany 2020-08-01 196/20-ek, DRKS00021705, PraeCoSa Phase Not Applicable Not yet recruiting 1 100 Christian Seeber 2020-08-06
PsyCovART: Psychological Impact of COVID-19 Among Women Undergoing Infertility Treatment Coronavirus disease 19 infection, Psychiatric disorder Female, Young Adults (18-44 yrs) Hospices Civils De Lyon France 2020-07-31 2020-12-31 69HCL20_0577, NCT04496869, PsyCovART Phase Not Applicable Not yet recruiting 1 5 Months 600 Eloise FRAISON, MD, Océane LABLANCHE, Resident 2020-08-06
COVID-19 Anosmia Study Coronavirus disease 19 infection, Dysomia omega-3 fatty acid alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mount Sinai Medical Center US 2020-07-15 2021-06-30 GCO 20-1132, NCT04495816 Phase 2 Clinical Recruiting 1 11 Months 126 Alfred-Marc Iloreta, MD, David K Lerner, MD 2020-08-06
A study of therapeutic effect of blood ozone therapy of severe Covid-19 patients Coronavirus disease 19 infection Variable regimens including IFN beta-1a , IFN beta-1b , atazanavir + ritanavir , chlroquine phosphate , dexamethasone , enoxaparin sodium , heparin , hydroxychloroquine , lopinavir + ritonavir , ozone HIV protease inhibitor, Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ahvaz University of Medical Sciences Iran 2020-08-05 IR.AJUMS.REC.1399.217, IRCT20200616047792N1 Phase 2 Clinical Recruiting 1 60 Behnam Sheibani, Dr. Behnam Sheibani, Dr. Mohammad Badavi, Shokrollah Salmanzadeh Ramhormozi 2020-08-06
A study of the COVID-19 sequlae Coronavirus disease 19 infection chest CT alone, pulmonary function test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Japanese Respiratory Society Japanese Ministry of Health, Labor and Welfare Japan 2020-08-01 UMIN000041168 Phase Not Applicable Not yet recruiting 1 1000 Akihito Yokoyama, Kazufumi Takamatsu 2020-08-06
COVID-19 Neurological Manifestation Coronavirus disease 19 infection, Neurological disease Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Pittsburgh US 2020-04-13 2020-12-31 NCT04496128, STUDY20040037 Phase Not Applicable No longer recruiting 1 8 Months 300 Sherry H Chou, MD, MSc 2020-08-06
COVID-19 Brain Injury Brain hemorrhage, Cerebral hemorrhage, Coronavirus disease 19 infection, Ischemic stroke, Status epilepticus, Traumatic brain injury Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Pittsburgh US 2020-04-02 2020-12-31 NCT04496076, STUDY20030201 Phase Not Applicable No longer recruiting 1 8 Months 300 Sherry H Chou, MD, MSc 2020-08-07
COPE: Covid-19 progression in end-stage kidney disease Coronavirus disease 19 infection, End stage renal disease Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) DaVita Clinical Research 2020-08-01 2021-03-31 20-M-0047-00, COPE, NCT04495907 Phase Not Applicable Not yet recruiting 0 8 Months 1000 2020-08-06
Evaluation of Commercial SARS-CoV-2 Antibody Immunoassays for COVID-19 Coronavirus disease 19 infection commercial SARS-CoV-2 antibody immunoassay alone Healthy volunteers accepted Hong Kong Sanatorium & Hospital Hong Kong 2020-07-27 2020-11-30 NCT04496141, RC-2020-12 Phase Not Applicable No longer recruiting 1 4 Months 70 Jonpaul Sze Tsing Zee, MBChB 2020-08-06
RePAiR: Registry of Sustained Immunity to COVID-19 Among ESKD Patients Coronavirus disease 19 infection, End stage renal disease Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) DaVita Clinical Research US 2020-07-20 2021-03-31 20-M-0044-00, NCT04495764, RePAiR Phase Not Applicable Recruiting 4 8 Months 2500 Aleah Freeman, Dylan Marias, Francesca Tentori, MD, Helen Brickel, RN, Jason Harvey 2020-08-06
A comparative study of the effects of Tocilizumab‎, interferon-gamma and vitamin C on the recovery of critically ill COVID-19 patients and cytokine storm Coronavirus disease 19 infection, Inflammatory disease routine medication alone, tocilizumab‎ alone, Vitamin C plus interferon gamma Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Tabriz University of Medical Sciences Iran 2020-07-31 IR.TBZMED.REC.1399.130, IRCT20200525047570N1 Phase 2 Clinical No longer recruiting 1 60 Mohammad Hossein Somi, Negin Hadisi 2020-08-07
Ethics of Behavioral Interventions during the Covid 19 Coronavirus disease 19 infection Ethics of Public Health Behavioral Interventions alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Forum for Ethical Review Committees in the Asian and Western Pacific Region (FERCAP) Seth GS Medical College India 2020-07-31 CTRI/2020/07/026926 Phase Not Applicable Not yet recruiting 5 400 Dr Yashashri C Shetty 2020-08-06
Desferal in COVID-19 Coronavirus disease 19 infection Desferal (Exirdaru Company) plus hydroxychloroquine sulfate (Amin Pharmaceutical company) Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bandare-abbas University of Medical Sciences Iran 2020-08-10 IR.HUMS.REC.1399.227, IRCT20200506047323N4 Phase 2/Phase 3 Clinical Not yet recruiting 1 60 Mohammad Fathalipour, Parivash Davoodian, Teamur Aghamolaei 2020-08-06
To see the effect of twakadi (tea made up of dalcheeni, tulasi pepper, clove, etc) tea on police worker who have a duty in covid 19 pandemic Coronavirus disease 19 infection Twakadi herbal tea (tulasi, Pippali, yashtimadhu, Ginger, Draksha, Dalchini) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) PDEAs C.A.R.C India 2020-07-31 CTRI/2020/07/026925 Phase 3 Clinical Not yet recruiting 1 60 Dr Yogini Kulkarni 2020-08-06
A Phase III clinical trial of of a two-dose regimen versus placebo of JNJ-78436735 for the prevention of Coronavirus disease 19 infection Coronavirus disease 19 infection JNJ-78436735 alone Johnson & Johnson Phase 3 Clinical Planned 0 2020-08-04
A phase I clinical trial of JNJ-78436735 for the prevention of Coronavirus disease 19 infection Coronavirus disease 19 infection JNJ-78436735 alone Johnson & Johnson Japan Phase 1 Clinical Planned 1 2020-08-04
A phase IIa clinical trial of JNJ-78436735 for the prevention of Coronavirus disease 19 infection Coronavirus disease 19 infection JNJ-78436735 alone Johnson & Johnson Spain, Germany, Netherlands Phase 2a Clinical Planned 3 2020-08-04
Evaluation study of preventing exacerbations for home care patients with chronic diseases by using dual-monitoring-based telenursing system - a prospective, longitudinal, mixed methods study Angina, Cardiac failure, Chronic obstructive pulmonary disease, Coronary artery disease, Coronavirus disease 19 infection, Diabetes mellitus, Diabetic nephropathy, Heart valve disease, Idiopathic pulmonary fibrosis, Lung tumor, Motor neurone disease, Myocardial disease, Pneumonia dual-monitoring telenursing alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hamamatsu University School of Medicine, St. Luke's International University Graduate School, Tokyo Healthcare University, Tokyoto Igaku Kenkyu Kiko Ministry of Education, Culture, Sports, Science and Technology of Japan Japan 2020-08-27 UMIN000041160 Phase Not Applicable Not yet recruiting 1 42 Tomoko Kamei 2020-08-07
Ayurvedic intervention in COVID-19 patients Coronavirus disease 19 infection Variable regimens including Ashwagandha (Withania somniferum) , Rasona Kalka , Samshamani Vati , Vyaghryadi kwatha Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) India 2020-08-04 CTRI/2020/07/026922 Phase 2 Clinical Not yet recruiting 1 30 Adil Rais 2020-08-06
BARCONA: BARCONA: A Study of Effects of Bardoxolone Methyl in Participants With SARS-Corona Virus-2 (COVID-19) Coronavirus disease 19 infection bardoxolone methyl (oral, pulmonary arterial hypertension/ diabetic nephropathy), Reata/ Kyowa Hakko Kirin alone I-kappa B kinase inhibitor, Kelch like ECH associated protein 1 modulator, NFE2L2 gene stimulator, Nuclear factor kappa B inhibitor, STAT3 gene inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) NYU Langone Health, Reata Pharmaceuticals Inc US 2020-08-01 2021-02-28 20-00591, BARCONA, NCT04494646 Phase 2/Phase 3 Clinical Not yet recruiting 1 7 Months 440 Alexander Slotwiner, MD, Atul Sharma, MD, Carlos Alviar, MD, Eugene Yuriditsky, MD, James Horowitz, MD, Juan Gaztanaga, MD, Kevin Chan, Kevin Marzo, MD, Norma Keller, MD, Sripal Bangalore, MD, MHA 2020-08-05
An integrated clinico-molecular-epidemiological approach to advance knowledge of COVID-19 Coronavirus disease 19 infection Monash University, Universiti Sains Malaysia Malaysia NMRR-20-1645-55277 Phase Not Applicable Not yet recruiting 5 Assoc. Prof Rosline Hassan, Associate Professor Qasim Ayub, DR Chan Yean Yean, DR HAJAH FAIZAN BINTI HAJI GHAZALI, Dr Murnihayati binti Hassan, Dr. Mohammad Ridhuan Bin Mohd Ali, Engku Nur Syafirah bt Engku Abd Rahman, Mr. Chua Wei Lian Chua Wei Lian, noor hafizan binti mat salleh 2020-08-06
KAP towards COVID-19 in RMCO, Sarawak Coronavirus disease 19 infection Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sarawak General Hospital Malaysia 2020-08-01 2020-08-31 NMRR-20-1643-55867 Phase Not Applicable Not yet recruiting 1 1 Month Dr. Benjamin Sachdev A/L Manjit Singh 2020-08-06
A Clinical trial to evaluate the effect of a combination of treatment of Reginmune capsule and Immunofree tablets in the treatment of mild to moderate COVID-19 patients Coronavirus disease 19 infection Immunofree alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Corival Lifesciences Private Limited India 2020-08-07 CTRI/2020/08/026957 Phase 4 Clinical Not yet recruiting 4 100 Dr Abhijit Munshi, Dr Vijaykumar Kamat 2020-08-05
Telemedicine effectiveness during COVID-19 Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Prasanna School of Public Health India 2020-08-10 CTRI/2020/08/026956 Phase Not Applicable Not yet recruiting 1 Brayal DSouza 2020-08-03
COVID-19 Drug Utilization Coronavirus disease 19 infection, Influenza virus infection, Respiratory tract infection COVID-19 treatment alone Ministry of Health, Malaysia Malaysia 2020-08-01 55865, NMRR-20-1648-55865 Phase Not Applicable Status not specified 1 Dr Abdul Haniff bin Mohamad Yahaya, Dr Nor Ilham Ainaa Binti Muhsin 2020-08-06
COVID-19 Preparedness and Response in Malaysia Coronavirus disease 19 infection Hospital Sungai Buloh Malaysia 2020-07-31 2020-08-07 55974, NMRR-20-1646-55974 Phase Not Applicable Status not specified 1 Dr Kalaiarasu Peariasamy, Dr Kuan Pei Xuan 2020-08-06
Comparison of three homoeopathic drugs for covid-19 immune boosters against standard treatment Coronavirus disease 19 infection Arsenicum album 30c alone, Camphora officinalis alone, Sarcolactic acid 30 alone, Variable regimens including Zinc Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ministry of Ayush, National Institute of Homoeopathy India 2020-08-03 CTRI/2020/07/026953 Phase 3 Clinical Not yet recruiting 1 704 Dr. Prasanta rath 2020-08-05
Survey and Management of depression, Anxiety and Stress due to COVID-19 fear Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression Brahmi (Bacopa monnieri (L.) Pennell) capsule alone Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) SDM College of Ayurveda and Hospital India 2020-08-01 CTRI/2020/07/026952, DAS-COVID-19-AYU Phase 2/Phase 3 Clinical Not yet recruiting 1 200 Dr Prasanna N Rao, Dr Shailaja U 2020-08-05
Effects of revised COVID-19 specific infection control protocol on the well being of dental professionals Coronavirus disease 19 infection personal protective equipment (PPE) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Manipal College of Dental Sciences India 2020-08-03 CTRI/2020/07/026943 Phase Not Applicable Not yet recruiting 1 300 Dr Shruthi Acharya 2020-08-05
A clinical trail of SARS-CoV-2 vaccine (protein subunit, outer membrane vesicle (OMV)-based peptide), Intravacc/ Epivax for the prevention of Covid-19 Coronavirus disease 19 infection SARS-CoV-2 vaccine (protein subunit, outer membrane vesicle (OMV)-based peptide), Intravacc/ Epivax alone COVID19 Spike glycoprotein modulator Intravacc Celonic AG Phase Not Applicable Planned 0 2020-08-03
Study of COVID-19 suspected pregnant women Coronavirus disease 19 infection Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Kasturba Medical College, Manipal India 2020-08-03 CTRI/2020/07/026942 Phase Not Applicable Not yet recruiting 1 200 Nivedita Hegde 2020-08-05
SARS-COV-2 Infection in Kidney Transplant Recipients: a Brazilian, Multicenter Study Coronavirus disease 19 infection, Kidney transplantation Hospital do Rim e Hipertensao Brazil 2020-05-21 2022-04-02 30631820.0.1001.8098, NCT04494776 Phase Not Applicable Recruiting 1 22 Months 500 Helio Tedesco, Jose Osmar Medina, Monica Nakamura 2020-08-05
What are risk factors associated with disease severity and length of hospital stay in patients admitted with COVID-19 in GCS Medical College, Hospital And Research Center, Ahmedabad? Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gujarat Cancer Society Medical college hospital and research centre India 2020-08-15 CTRI/2020/07/026955 Phase Not Applicable Not yet recruiting 1 910 Arpit C Prajapati 2020-08-04
Study of blood tests findings in patients of COVID 19 in a tertiary care center Coronavirus disease 19 infection Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gujarat Cancer Society Medical college hospital and research centre India 2020-08-10 CTRI/2020/07/026954 Phase Not Applicable Not yet recruiting 1 150 Dr Himali Thakkar 2020-08-04
Clazakizumab versus Placebo - COVID-19 Infection Coronavirus disease 19 infection, Lung disease, Lung injury, Respiratory distress syndrome, Viral pneumonia clazakizumab alone IL-6 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Houston Methodist US 2020-07-13 2021-07-31 NCT04494724, PRO00025969 Phase 2 Clinical Recruiting 1 12 Months 60 Ahmad Goodarzi, MD, Ahmed O Gaber, MD, Alex Rogers, PharmD, Darrel Cleere, BSN, Faisal Zahiruddin, MD, Howard Huang, MD, Howard J Huang, MD, Isioma Agboli, MD, Linda W Moore, PhD, Simon Yau, MD, Yihad G Youssef, MD 2020-08-06
A clinical study to evaluate the translational insights to better understand the immune response in COVID-19 patients ie, association of COVID-19 inflammation with activation of the C5a-C5aR1 Coronavirus disease 19 infection Innate Pharma SA Phase Not Applicable Status not specified 0 2020-08-05
Observational study of SARS-CoV-2 antibody test positive rate Coronavirus disease 19 infection SARS-CoV-2 antibody test alone SOUSEIKAI Japan 2020-08-01 UMIN000041262 Phase Not Applicable Recruiting 1 4000 Shin Irie, Tatsuya Yoshihara 2020-08-05
ULSC: Umbilical Cord Lining Stem Cells (ULSC) in Patients With COVID-19 ARDS Coronavirus disease 19 infection, Respiratory distress syndrome umbilical cord lining stem cells alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Restem LLC US 2020-07-23 2021-11-30 NCT04494386, ULSC, ULSC-CV-01 Phase 1/Phase 2 Clinical Recruiting 1 16 Months 60 Jason Knudtson, MD, Jason Knudtson, Md, William C Spanos, MD, William C Spanos, Md 2020-08-05
A Study to Investigate the Pharmacokinetics, Efficacy and Safety of INM-005 in Patients With COVID-19 Coronavirus disease 19 infection INM-005 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Inmunova Argentina 2020-07-27 2020-11-30 CT-INM005-01, NCT04494984 Phase 2/Phase 3 Clinical Recruiting 6 4 Months 242 Augusto Perez, MD, Beatriz Firmenich, Estela Izquierdo, MD, Fernando Grittini, MD, Gustavo Chaparro, MD, Ines Zapiola, Mariana Colonna, MSc., Santiago Sanguineti, Ph.D. 2020-08-05
COVID-19 Core Warming Coronavirus disease 19 infection, Respiratory failure EnsoETM alone, core warming alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Advanced Cooling Therapy Inc, Attune Medical Sharp HealthCare US 2020-08-31 2020-12-31 COVID CORE WARMING, COVID-19 Core Warming, NCT04494867 Phase Not Applicable Recruiting 1 4 Months 20 Ahmed Salem, MD, David Willms, MD, Katie Miller 2020-08-06
Multicenter, registry study of Japanese patients with inflammatory bowel disease with COVID-19 Behcets disease, Coronavirus disease 19 infection, Crohns disease, Inflammatory bowel disease, Ulcer, Ulcerative colitis Japanese Ancestry Sapporo Medical University School of Medicine Japanese Ministry of Health, Labor and Welfare Japan 2020-08-01 UMIN000040656 Phase Not Applicable Not yet recruiting 1 200 DAISUKE HIRAYAMA, HIROSHI NAKASE 2020-08-05
ImmuneRACE: Immune Response Action to COVID-19 Events Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Adaptive Biotechnologies Corp Covance Inc US 2020-04-24 2021-01-31 ADAP-006, ImmuneRACE, NCT04494893 Phase Not Applicable Recruiting 1 9 Months 1000 Emily A Svejnoha, BS, Emily Svejnoha, BS, Jen N Dines, MD 2020-08-06
IFN Beta-1b and Ribavirin for Covid-19 Coronavirus disease 19 infection standard care alone, interferon beta-1b plus ribavirin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The University of Hong Kong Hospital Authority,Hong Kong Hong Kong 2020-07-29 2022-08-01 NCT04494399, UW 20-513 Phase 2 Clinical Recruiting 1 24 Months 96 Ivan FN Hung, MD FRCP, Kelvin KW To, MD FRCPath, Kelvin To, MD MRCP 2020-08-05
Improving Food Pleasure and Intake of Oncology Patients Receiving Chemotherapy Breast tumor, Colorectal tumor, Coronavirus disease 19 infection standard adjuvat chemotherapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universita degli Studi di Firenze Italy 2021-01-31 2022-12-31 ALTERTASTE, NCT04495387 Phase Not Applicable Not yet recruiting 1 23 Months 100 Giandomenico Roviello 2020-08-05
Effect of a Combination of Treatment of Reginmune Capsule and Immunofree Tablets in the Treatment of Mild to Moderate COVID-19 Patients Coronavirus disease 19 infection Immunofree plus Reginmune Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Nutrin GmbH India 2020-08-07 2020-09-30 MGCTS/20/105, NCT04494204 Phase 2/Phase 3 Clinical Not yet recruiting 1 1 Month 100 Abhijit Munshi, Apurve Mehra, PUNEET MITTAL, Puneet Mittal, Vijaykumar Kamat 2020-08-05
CABS: COVID-19 cancer attitudes and behaviour study Cancer, Coronavirus disease 19 infection online survey alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry, African Ancestry Cardiff University United Kingdom Research & Innovation UK 2020-06-30 2021-12-29 CABS, ISRCTN17782018 Phase Not Applicable Not yet recruiting 2 18 Months 3535 Ms Moriarty 2020-08-06
Neonatal complications of coronavirus disease (COVID-19) study Coronavirus disease 19 infection Newborn Infants (up to 5 months) University of Oxford National Institute for Health Research (NIHR) UK 2020-03-01 2021-09-30 IRAS 282127, ISRCTN60033461 Phase Not Applicable Recruiting 2 19 Months Dr Gale, Prof Jenny Kurinczuk 2020-08-06
Evaluation of the Patient-Doctor-Relationship during the COVID-19 pandemia Coronavirus disease 19 infection Survey-based Assessment alone, traditional face mask alone, transparent face mask alone University of Munster Germany 2020-08-03 2020-498-f-S, DRKS00022305 Phase Not Applicable Recruiting 1 500 Kristian Nikolaus Schneider 2020-08-04
A prospective (compassionate), open-label, single-center study to evaluate efficacy of remdesivir in patients with SARS-CoV-2 pneumonia Coronavirus disease 19 infection, Pneumonia remdesivir alone COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Ospedale Luigi Sacco Azienda Ospedaliera Polo Universitario, Universita degli Studi di Milano Italy 2020-02-23 Phase 2 Clinical Status not specified 1 35 2020-08-04
Mavrilimumab to Reduce Progression of Acute Respiratory Failure in COVID-19 Pneumonia and Systemic Hyper-inflammation Coronavirus disease 19 infection, Hypoxia, Inflammatory disease, Respiratory failure, Viral pneumonia mavrilimumab alone C-reactive protein inhibitor, Chemokine CC22 ligand inhibitor, GM-CSF receptor antagonist, Hemoglobin scavenger receptor antagonist, Metalloprotease-1 inhibitor, Metalloprotease-3 inhibitor, Small inducible cytokine A17 ligand inhibitor, VEGF gene inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Cincinnati Kiniksa Pharmaceuticals Ltd US 2020-05-20 2021-05-31 IND 149353, NCT04492514 Phase 2 Clinical Recruiting 1 12 Months 60 Autumn Cresie, Kristin Hudock, MD 2020-08-03
Cyclosporine For The Treatment Of COVID-19(+) Coronavirus disease 19 infection ciclosporin, Novartis alone, standard of care alone Calcineurin inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Baylor College of Medicine Brigham & Women's Hospital US 2020-08-20 2025-08-20 H-48163, NCT04492891 Phase 2a Clinical Not yet recruiting 1 60 Months 75 Bryan Burt, MD, Michelle Almarez, BBA 2020-08-03
HOME-COVID-19: Mental Health Circumstances Among Healthcare Workers and General Public Under the Pandemic Situation of COVID-19 Coronavirus disease 19 infection, Psychiatric disorder online survey alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chiang Mai University Thailand 2020-04-21 HOME-COVID-19, TCTR20200425001 Phase Not Applicable Recruiting 1 2500 Surapon Nochaiwong 2020-08-03
Effect of CRP blood test in management of COVID 19 patients Coronavirus disease 19 infection CRP test alone Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gujarat Cancer Society Medical college hospital and research centre India 2020-08-05 CTRI/2020/07/026902 Phase Not Applicable Not yet recruiting 1 100 Impact of CRP test in management of COVID 19 2020-08-03
Investigational Treatments for COVID-19 in Tertiary Care Hospital of Pakistan Coronavirus disease 19 infection, Hypoxia, Respiratory failure, Viral pneumonia Fresh frozen Plasma alone, Variable regimens including Fresh frozen Plasma , convalescent Plasma , mesenchymal stem cell therapy , remdesivir , tocilizumab COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) United Nations International Children's Fund Pak Emirates Military Hospital Pakistan 2020-04-01 2020-07-20 NCT04492501, SULTAN MEHMOOD KAMRAN 3 Phase 2 Clinical Completed 1 3 Months 600 Sultan mehmood kamran, Sumaira Irum, MIT 2020-08-03
Virtual exercise for older persons during COVID-19 pandemic Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression Exercises alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Malaya Malaysia 2020-06-01 2020-08-15 55960, NMRR-20-1629-55960 Phase Not Applicable No longer recruiting 1 2 Months AMIRAH FATIN BINTI IBRAHIM, Dr Tan Maw Pin, Mrs Chong Mei Chan 2020-08-05
Impact of COVID-19 Pandemic on Genetic Services across Asia Coronavirus disease 19 infection telegenetics alone Genetic Counselling Society of Malaysia Malaysia 2020-07-28 2020-08-31 55195, NMRR-20-1640-55195 Phase Not Applicable Not yet recruiting 2 1 Month 30 Ms Juliana Lee Mei Har, Ms Yoon Sook-Yee, Prof Dr Thong Meow Keong 2020-08-05
Detection of Antibodies to COVID-19 Coronavirus disease 19 infection VITROS 3600 system alone, VITROS 5600 system alone, VITROS CoV2T assay alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ortho Clinical Diagnostics India Private Limited India 2020-08-03 CTRI/2020/07/026759 Phase Not Applicable Not yet recruiting 1 175 Dr Smita Sarma 2020-08-03
Vitamin-D levels in COVID-19 Patients and their relationship with other bone metabolism markers Coronavirus disease 19 infection, Metabolic bone disease, Vitamin D deficiency Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences, Raipur India 2020-08-03 181 R4, AIIMSRPR/IEC/2020/553, CTRI/2020/07/026794 Phase Not Applicable Not yet recruiting 1 100 Alok Chandra Agrawal 2020-08-05
ACTT-3: Adaptive COVID-19 Treatment Trial 3 Coronavirus disease 19 infection recombinant interferon beta-1a, Merck Serono plus remdesivir COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, Interferon beta ligand, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Allergy and Infectious Diseases US 2020-08-04 2023-11-01 20-0006 ACTT-3, ACTT-3, NCT04492475 Phase 3 Clinical Not yet recruiting 4 38 Months 1038 20-0006 Central Contact 2020-08-07
MICI-Covid-19: Inflammatory Bowel Disease (IBD) and Covid-19 Infection Coronavirus disease 19 infection biological testing alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopitaux Universitaires de Strasbourg France 2020-07-07 2021-01-07 7930, MICI-Covid-19, NCT04492267 Phase Not Applicable Recruiting 1 6 Months 700 Bénédicte CARON, MD, Jean-Marie REIMUND, MD, PhD, Saïd CHAYER, PhD, HDR, Yves ARONDEL, MD 2020-08-04
An independent study to evaluate the performance of MosaiQ COVID-19 Antibody Microarray in the detection of COVID-19 antibodies in patients with COVID-19 infection Coronavirus disease 19 infection MosaiQ COVID-19 Antibody Microarray alone Quotient Ltd Phase Not Applicable Status not specified 0 500 2020-08-03
GSK-3739937 First-Time-In-Human (FTIH) Study in Healthy Volunteers Coronavirus disease 19 infection, HIV infection GSK-3739937 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) GlaxoSmithKline plc 2020-07-31 2021-02-17 212548, NCT04493684 Phase 1 Clinical Not yet recruiting 0 6 Months 48 EU GSK Clinical Trials Call Center, GSK Clinical Trials, US GSK Clinical Trials Call Center 2020-08-03
A phase III clinical trial of TY-027 in patients with COVID-19 Coronavirus disease 19 infection TY-027, Tychan alone Tychan Pte Ltd Phase 3 Clinical Planned 0 2020-08-03
Affect in surgical care in children due to COVID 19 in India: a online survey of surgeons Coronavirus disease 19 infection online survey alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Chacha Nehru Bal Chikitsalya India 2020-07-30 CTRI/2020/07/026792 Phase Not Applicable Not yet recruiting 1 200 Niyaz Khan 2020-08-05
Panchgavya Therapy in prophylaxis and as an adjuvant therapy in management of Covid 19. Coronavirus disease 19 infection Panchgavya Therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ionisation Filtration Industries PvtLtd India 2020-07-31 CTRI/2020/07/026793, MHC/CT/20-21/010 Phase 2 Clinical Not yet recruiting 1 120 Dilip Kulkarni, Gayatri Ganu, Vivek Joshi 2020-08-03
RESIST Trial: Statin and Aspirin in SARS-CoV-2 infection Coronavirus disease 19 infection Aspirin alone, atorvastatin alone HMG CoA reductase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Medical Sciences India 2020-08-01 CTRI/2020/07/026791, RESIST Trial Phase 2/Phase 3 Clinical Not yet recruiting 1 800 Dr Deepti Siddharthan 2020-08-05
Treatment for Moderate/Severe COVID-19 in a Fragile and Vulnerable Population, Admitted to a Geriatric Hospital Unit or in a Transicional Care Center Coronavirus disease 19 infection, Dyspnea, Respiratory failure, Upper respiratory tract infection, Viral pneumonia colchicine plus prednisone Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundacion Clinic per a la Recerca Biomédica Spain 2020-09-30 2021-10-31 2020-002462-14, NCT04492358 Phase 2/Phase 3 Clinical Not yet recruiting 1 13 Months 144 Maria Joyera Rodríguez 2020-08-03
A trial to evaluate the effect of cotton face-masks and other behavioral factors on COVID-19 risk in rural Telangana Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Synergy India 2020-08-03 CTRI/2020/07/026796 Phase Not Applicable Not yet recruiting 1 10000 Teena Desai 2020-08-03
Plasma of donors convaling by COVID-19, for the management of patients with SARS-CoV-2 illness by in Stage II (moderate) and Stage III (Severe): Multicenter, Double-blind, Randomized Study Coronavirus disease 19 infection convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Naval Medical Center at San Diego Mexico 2020-05-18 CE/168/20 Phase 2 Clinical Recruiting 1 50 NAVAL MEDICAL CENTER 2020-08-03
Clinical Trial of Treatment in Adult Patients with Pneumonia by COVID-19 Coronavirus disease 19 infection, Viral pneumonia tocilizumab alone, Variable regimens including azithromycin , hydroxychloroquine , lopinavir + ritonavir HIV protease inhibitor American British Cowdray Medical Center Mexico 2020-07-10 ABC-20-07 Phase 2 Clinical Recruiting 1 36 PAULINA TRÁPAGA SÁNCHEZ 2020-08-03
Efficacy and safety of convalescent plasma donors by COVID-19 in patients with severe acute respiratory infection syndrome due to the SARS-COV-2 virus Coronavirus disease 19 infection, Respiratory distress syndrome convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Health Research Council of Mexican Institute of Social Security Mexico 2020-04-22 2020-785-029 Phase 3 Clinical Recruiting 4 400 2020-08-03
TARGET-COVID: The Evaluation of Hemostasis in Hospitalized COVID-19 Patients Bleeding, Coronavirus disease 19 infection, Thrombosis, Viral pneumonia TEG6s hemostasis analyzer alone, biological sampling alone, genotyping alone, phlebotomy alone, thrombelastography alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) LifeBridge Health Chrono-Log Corp, Haemonetics Corp, Inflammatory Markers Laboratory, Precision Biologics Inc US 2020-06-30 2021-06-30 1602903, NCT04493307, TARGET-COVID Phase Not Applicable Recruiting 1 12 Months 100 Ashwin Dharmadhikari, MD, Cescelle B Barbour, MSN, Cescelle Barbour, MSN, Jaime Barnes, DO, Kevin P Bliden, B.S. MBA, Paul A Gurbel, MD, kevin bliden, MBA 2020-08-03
An observational study of lying down flat on chest in treatment of corona patient who breath on their own and on oxygen therapy Coronavirus disease 19 infection Oxygen therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) New Civil Hospital, Surat India CTRI/2020/07/026797 Phase Not Applicable Not yet recruiting 1 111 Shweta Apatel 2020-08-05
SCCT: Singapore COVID-19 Chemosensory Tracking (SCCT) Study Coronavirus disease 19 infection, Respiratory disease home-use standardized smell and taste test alone, online software (CompuSense) alone, taste test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Clinical Nutrition Research Centre, Singapore National University Hospital (Singapore) Pte Ltd Singapore 2020-07-23 2021-03-31 2020/00810, NCT04492904, SCCT Phase Not Applicable Recruiting 1 8 Months 5000 Ciaran Forde, Phd, Vicki Tan 2020-08-03
SWITCH-COVID: Switch of Renin-Angiotensin System Inhibitors in Patients With Covid-19 Coronavirus disease 19 infection, Hypertension anti-hypertensive class drug therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Sao Paulo Brazil 2020-07-25 2022-02-14 33575220.9.0000.0068, NCT04493359, SWITCH-COVID Phase 2/Phase 3 Clinical Recruiting 1 18 Months 240 Bruno Caramelli, Bruno Caramelli, MD.PHD, Bruno F Caramelli, MD.PHD, Caio A Tavares, MD 2020-08-03
COVITA: Containment Measures and Eating Disorders Coronavirus disease 19 infection, Eating disorder Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Montpellier Inserm U1061 France 2020-04-01 2020-06-30 COVITA, NCT04492189, RECHMPL20_0220 Phase Not Applicable Completed 1 3 Months 40 Ariane SULTAN, PR 2020-08-03
In this study selenium levels would be determined in both normal volunteers as well as patients suffering from COVID-19 Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Sami Labs Ltd India 2020-07-24 CPL/88/EPL_COVD/I/JUL/20,V2.0, CTRI/2020/07/026747 Phase Not Applicable Not yet recruiting 2 60 Dr Kalpesh Shah, Dr S Krishnamoorthy, Dr Santhan Perithambi Sadagopal 2020-08-03
ACTIV: Analysis of Chronic Non-infectious Diseases Dynamics After COVID-19 Infection in Adult Patients Asthma, Chronic obstructive pulmonary disease, Coronavirus disease 19 infection, Diabetes mellitus, End stage renal disease, Vascular disease Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Eurasian Association of Therapists Russian Federation 2020-06-11 2022-01-15 ACTIV, ACTIV11062020, NCT04492384 Phase Not Applicable Recruiting 1 19 Months 3500 Alexander Arutyunov, professor, Anastasia Rud, Anastasia Rud, master, Tamara Kriukova, Tamara Kriukova, master 2020-08-04
Using Neuromodulation to Improve Parkinson's Disease Coronavirus disease 19 infection, Parkinsons disease ThermoNeuroModulation device (Scion Neurostim Llc) alone, time-varying caloric vestibular stimulation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Wake Forest University Health Sciences, US Scion Neurostim Llc US 2020-09-30 2022-09-30 IRB00067408, NCT04493697 Phase Not Applicable Not yet recruiting 1 24 Months 20 Christopher T Whitlow, MD, Richarlette C Hightower 2020-08-03
MSCT Chest in Suspected COVID-19 Patients Coronavirus disease 19 infection, Respiratory disease, Viral pneumonia RT-PCR alone, multi spiral computed tomography (MSCT) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assiut University Egypt 2020-07-30 2020-10-30 CTCOV, NCT04492865 Phase Not Applicable Not yet recruiting 1 3 Months 150 Abeer Ali, M D, Dalia Kamal, M D, Gehan S Seifeldein, M.D., Gehan S. Seifeldein, Marwa Khairallah, M D, Salwa Seif Eldein, PhD, Salwa Seif Eldin, PhD, Sara Hassanin, MD, Walaa Ali, M D 2020-08-03
To Observe Whether Isoflurane Can Treat COVID-19 Patients Coronavirus disease 19 infection, Viral infection, Viral pneumonia isoflurane alone, mechanical ventilation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Massachusetts General Hospital US 2020-04-20 2020-07-20 2020P001048, NCT04492943 Phase 4 Clinical Recruiting 1 3 Months 40 Zhongcong Xie, Zhongcong Xie, M.D., Ph.D, Zhongcong Xie, PhD, MD 2020-08-04
A cohort study to evaluate the impact of COVID-19 infection on neurological integrity using Simoa NF-light kit on the Simoa HD-X Analyzer in adult patients with mild to moderate COVID-19 infection Coronavirus disease 19 infection, Neurological disease Simoa HD-X Analyzer alone, Simoa NF-light kit alone University Hospital Basel, University Hospital Regensburg Switzerland, Germany Phase Not Applicable Status not specified 2 100 Jens Kuhle 2020-08-03
Knowledge Attitude and Practice of Nurses towards Hand hygiene in COVID-19 care units Coronavirus disease 19 infection Healthy volunteers accepted Government Medical College Kannur India 2020-08-10 CTRI/2020/07/026758 Phase Not Applicable Not yet recruiting 1 100 Dr Venugopalan A K 2020-08-04
An interventional study to access the effect of Homoeopathic medicine in positive cases of COVID-19 Coronavirus disease 19 infection Eupatorium perfoliatum 30 C alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ministry of Ayush India 2020-07-31 CTRI/2020/07/026757 Phase 3 Clinical Not yet recruiting 1 200 Dr Tapan Nath, Prof Dr PK Goswami 2020-08-04
Turkish of the SARS-CoV-2 Anxiety Scale Anxiety disorder, Coronavirus disease 19 infection survey work alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Eskisehir Osmangazi University Turkey 2020-07-24 2020-12-24 AYFER AÇIKGÖZ, DENİZ YİĞİT, DSAYIK2, ERTUĞRUL ÇOLAK, NCT04490473, ÖZLEM MUMCU Phase Not Applicable Recruiting 1 5 Months 300 AYFER AÇIKGÖZ, DENIZ YIGIT, DILEK SAYIK 2020-08-04
FGG: Fear learning during pandemic fear: how COVID-19 perception affects classical fear conditioning Coronavirus disease 19 infection, Psychiatric disorder Healthy volunteers accepted, Young Adults (18-44 yrs) Universitat des Saarlandes Germany 2020-08-02 DRKS00022761, FGG Phase Not Applicable Recruiting 1 120 Mr. M.Sc. Alexander Hauck 2020-08-04
KiTaCoviDD19: SARS-CoV-2 Surveillance in Day Care Centers (COVID-19) Coronavirus disease 19 infection University Hospital Carl Gustav Carus Germany 2020-07-15 DRKS00022729, KiTaCoviDD19 Phase Not Applicable Recruiting 1 750 Dr. med. Jakob Armann 2020-08-04
EMN-COVID: COVID-19 Infection and Multiple Myeloma Coronavirus disease 19 infection, Multiple myeloma Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) European Myeloma Network Fondazione EMN Italy Italy, Netherlands, Germany, UK, Austria, Czech Republic, Belgium, Greece 2020-07-01 2021-07-31 EMN-COVID, EMN-COVID, NCT04492371 Phase Not Applicable Recruiting 8 13 Months 500 Evangelos Terpos, Prof., Gordon Cook, Prof., Hermann Einsele, Prof., Maria Krauth, Prof., Marie-Christiane Vekemans, Prof., Mario Boccadoro, Prof., Roman Hajek, Prof., Sonja Zweegman, Prof. 2020-08-04
A phase II clinical trial of TXA-127 for the potential treatment of COVID-19 infection Coronavirus disease 19 infection TXA-127 alone Angiotensin II receptor modulator Constant Therapeutics LLC Israel Phase 2 Clinical Planned 2 2020-08-03
A phase II clinical trial of TXA-127 for the potential treatment of COVID-19 infection Coronavirus disease 19 infection TXA-127 alone Angiotensin II receptor modulator Constant Therapeutics LLC Italy Phase 2 Clinical Planned 1 2020-08-03
The effect of Cognitive behaviour therapy on adult mental health during the COVID-19 pandemic Anxiety disorder, Coronavirus disease 19 infection, Depression CBT self-help guide immediately alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Curtin University, Government of Western Australia Department of Health Australia ACTRN12620000779976p, RES-62642 Phase Not Applicable Not yet recruiting 1 100 Dr Sarah Egan 2020-08-04
CORE-THROMBOSIS: Covid-19 registry on thrombosis complications associated with hospitalization Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Johannes Gutenberg Universitat Mainz Belgium, Netherlands, Germany, UK, Italy 2020-04-15 2020-14990-retrospektiv, CORE-THROMBOSIS, CTH C010, DRKS00022277 Phase Not Applicable Recruiting 5 5000 Stavros Konstantinides 2020-08-04
Persistent lung and arterial inflammation following COVID-19 pneumonia Arteritis, Coronavirus disease 19 infection, Lung inflammation, Viral pneumonia 18F-FDG PET/CT scan alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sir Charles Gairdner Hospital Australia 2020-08-03 ACTRN12620000778987p Phase Not Applicable Not yet recruiting 3 30 A/Prof Roslyn Francis, Ms Elaine Campbell 2020-08-04
COVID-VTE follow-up study: COVID-VTE follow-up study Coronavirus disease 19 infection, Thromboembolism Application of the patient pathway alone Leiden University Medical Center The Netherlands Organisation for Health Research and Development, Trombosestichting Nederland 2020-06-01 2020-052, COVID-VTE follow-up study, NL8787 Phase Not Applicable Recruiting 0 400 Erik Klok 2020-08-04
COVID-19: Yoga for Nurses (COVID-19) Coronavirus disease 19 infection Deep Relaxation Technique alone, Yoga alone, stretch breathing excercise alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Sri Devaraj Urs Academy of Higher Education and Research India 2020-08-04 COVID-19, CTRI/2020/07/026799 Phase 2/Phase 3 Clinical Not yet recruiting 1 60 Patil NJ 2020-08-04
A study to assess the effiacy of RTB-101 in preventing symptom development and downstream hospitalizations among positive, asymptomatic patients as well as any cohabitants of patients diagnosed with COVID-19 in community/outpatient setting Coronavirus disease 19 infection dactolisib alone Phosphoinositide 3-kinase inhibitor, mTOR complex 1 inhibitor, mTOR complex 2 inhibitor TrialSpark, resTORbio Inc Phase Not Applicable Planned 0 2020-08-03
A study to campare various blood investigations in COVID-19 positive patients Coronavirus disease 19 infection Inflammatory markers analysis alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Max Superspeciality Hospital Vaishali India 2020-08-03 CTRI/2020/07/026800 Phase Not Applicable Recruiting 1 72 Dhananjay Batwara 2020-08-04
EPI-COVID-POP: COVID-19 Seroprevalence Study in French Guiana Coronavirus disease 19 infection Blood sample alone Healthy volunteers accepted Institut Pasteur de Guyane Centre Hospitalier de Cayenne, Eurofins Guyane Laboratory in Rémire-Montjoly, Kourou Medical Biology Laboratory, French Guiana 2020-07-15 2021-07-15 2020-048, EPI-COVID-POP, NCT04490850 Phase Not Applicable Recruiting 5 12 Months 1500 Claude Flamand, PhD, Didier Didier, Emmanuel Belliard, Jean-François Carod, Thierry Carage, Véronique Servas 2020-08-04
COVID-19EXO: Evaluation of safety and efficiency of method of exosome inhalation in SARS-COV-2 associated pneumonia Coronavirus disease 19 infection, Viral pneumonia EXO 1 inhalation alone, EXO 2 inhalation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Clinical Center of Cellular Technologies Samara Regional Clinical Hospital Russian Federation 2020-07-20 2021-01-30 COVID-19 EXO, COVID-19EXO, NCT04491240 Phase 1/Phase 2 Clinical Recruiting 1 6 Months 90 2020-08-05
CoV-PICS: A Virtual Post-ICU Clinic Coronavirus disease 19 infection Medical Record Review - Inpatient Treatment alone, Online Questionnaires alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Washington University School of Medicine, US US 2020-08-01 2021-07-30 202007053, NCT04490278 Phase Not Applicable Not yet recruiting 1 11 Months 80 Beth Taylor, DCN, Chris Palmer, MD 2020-08-04
A prospective, open-label study to evaluate the safety and efficacy of ExoFlo in the treatment of critically ill patients with moderate to severe ARDS caused by COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome ExoFlo alone Christ Hospital US Phase 2 Clinical Status not specified 3 Angel Lazo, Jr, Sascha Sengupta, Vikram Sengupta 2020-08-03
COACH: Student-delivered Telehealth Program for COVID19 Education and Health Promotion Coronavirus disease 19 infection Telehealth coaching sessions alone Healthy volunteers accepted, Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of British Columbia Canada 2020-07-28 2021-07-31 COACH, COACH, NCT04492527 Phase Not Applicable Recruiting 1 12 Months 75 Brodie Sakakibara, PhD, Cam Clayton, MSc, Chelsea Pelletier, PhD, Devin Harris, MD, Jill Zwicker, PhD, Julia Schmidt, PhD, Michelle C Yang, BSc 2020-08-05
NEOSCREENCOVID: COVID-19 Infection Screening in Cancer Patients Coronavirus disease 19 infection rapid serological test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Antoine Lacassagne (Nice) France 2020-07-21 2021-03-31 2020/23, NCT04492410, NEOSCREENCOVID Phase Not Applicable Recruiting 1 8 Months 500 Sandrine CHELI, PhD 2020-08-03
ketocovidiet: Eucaloric Ketogenic Diet in COVID-19 Cytokine Storm Syndrome Coronavirus disease 19 infection, Respiratory distress syndrome Ketogenic diet alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) IRCCS AOU San Martino – IST Italy 2020-09-01 2021-05-30 KETOCOV-1, NCT04492228, ketocovidiet Phase Not Applicable Not yet recruiting 1 8 Months 100 Samir G Sukkar, MD 2020-08-05
Knowledge, Attitudes, and Practices Towards COVID-19 Among Health Care Professionals Among Healthcare Professionals Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Istinye Universitesi Turkey 2020-08-01 2020-12-10 00010, NCT04492202 Phase Not Applicable Not yet recruiting 1 4 Months 200 Aysegul Asalioglu, Yasemin ÇIRAK, Assoc. Prof. 2020-08-04
Clearing the Fog: Is Hydroxychloroquine Effective in Reducing COVID-19 Progression (COVID-19) Coronavirus disease 19 infection hydroxychloroquine alone, Variable regimens including Panadol , vitamin C , vitamin D , zinc Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) United Nations International Children's Fund Pak Emirates Military Hospital Pakistan 2020-04-10 2020-05-31 NCT04491994, SULTAN MEHMOOD KAMRAN 2 Phase 2 Clinical Completed 1 1 Month 500 Imran m Fazal, FCPS, Sultan mehmood kamran 2020-08-04
Low Dose Whole Lung Radiotherapy for Older Patients With COVID-19 Pneumonitis Coronavirus disease 19 infection, Viral pneumonia low dose whole lung radiotherapy alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kantonsspital Graubuenden US, Switzerland 2020-11-30 2021-12-31 IGRG01, NCT04493294 Phase 1/Phase 2 Clinical Not yet recruiting 2 13 Months 500 Brigitta G Baumert, M.D.Ph.D, Nam Nguyen, Nam p Nguyen, MD 2020-08-04
Ayurveda strength and immunity enhancing protocol and immunity in health care workers : clinical trial of an Ayurveda Intervention Coronavirus disease 19 infection AYUSH Kadha alone, Anu taila alone, Chyavanprash alone, Pranayama alone, Shanshamni Vati alone, Yoga alone, rock salt alone, turmeric alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) All India Institute of Ayurveda India 2020-07-28 CTRI/2020/07/026756 Phase Not Applicable Not yet recruiting 1 425 Dr Santosh Kumar Bhatted, Dr Tanuja Manoj Nesari 2020-08-04
Clinical severity and outcome among COVID-19 infected patients in respect to viral load and immune and inflammatory response Coronavirus disease 19 infection Healthy volunteers accepted, Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) RUHS College of Medical Sciences India 2020-07-27 CTRI/2020/07/026755 Phase Not Applicable Not yet recruiting 1 200 Sonali Sharma 2020-08-04
Evaluation of Systemic and Oral Conditions of Pregnant Women and Their Babies, With Exposure to COVID-19 Infection Coronavirus disease 19 infection, Periodontal disease Healthy volunteers accepted, Female, Adolescents (13-17 yrs), Young Adults (18-44 yrs) University of Sao Paulo Bauru School of Dentistry Brazil 2020-09-30 2022-12-31 FOBPREGNAT, NCT04492449 Phase Not Applicable Not yet recruiting 1 27 Months 260 2020-08-04
Hyponatremia in covid-19 patients Coronavirus disease 19 infection, Hyponatremia, Inflammatory disease Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Nacional Profesor Alejandro Posadas Argentina 2020-03-07 2020-07-21 HYPONATREMIA IN COVID PATIENTS, NCT04493268 Phase Not Applicable Completed 1 4 Months 250 CARLOS EGHI, physician, Ladislao Diaz Ballve, GRADUATE IN KINESIOLOGY 2020-08-04
An observational, retrospective study to evaluate the impact of low dose tocilizumab on mortality rate in patients with COVID-19 related pneumonia Coronavirus disease 19 infection, Pneumonia, Respiratory failure standard of care alone, tocilizumab alone Montichiari hospital Italy Phase Not Applicable Status not specified 1 85 2020-08-03
Multicenter, randomized, controlled, open-label study to study the efficacy and safety of asunercept in patients with severe COVID-19 disease Coronavirus disease 19 infection asunercept alone, standard of care alone CD95 antagonist Apogenix GmbH Spain, Russian Federation 2020-07-24 2021-12-31 APG101_CD_017 Phase 2 Clinical Not yet recruiting 8 17 Months 400 2020-08-04
The impact of coronavirus on mental health and well-being in Wales Acute stress disorder, Coronavirus disease 19 infection, Psychiatric disorder, Suicidal ideation online survey alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Swansea University, Wales UK 2020-05-04 2020-07-13 ISRCTN21598625 Phase Not Applicable Completed 2 2 Months 15469 Prof Gray 2020-08-05
EXIT COVID-19: Extracellular Vesicle Infusion Therapy for Severe COVID-19 Coronavirus disease 19 infection, Hypoxia, Respiratory distress syndrome, Respiratory failure ExoFlo, Direct Biologics LLC alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Direct Biologics LLC US 2020-09-01 2020-12-31 DB-001, EXIT COVID-19, NCT04493242 Phase 2 Clinical Not yet recruiting 1 4 Months 60 Vikram Sengupta, Principal Investigator 2020-08-04
The epidemiological characteristic of real-time covid-19 cases in north-eastern peninsular Malaysia: Jan to July 2020 Coronavirus disease 19 infection Jabatan Kesihatan Negeri Kelantan 2020-07-30 NMRR-20-1624-55900 Phase Not Applicable Status not specified 0 Dr HAZLIENOR BINTI MOHD HATTA 2020-08-06
Good-NIGHT COVID: Nasal washout and gargling for healthcare staff in Care Homes during the COVID-19 pandemic: The Good-NIGHT COVID pilot study Coronavirus disease 19 infection Gargling alone, Nasal lavage alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Of Southampton NIHR Applied Research Collaboration Wessex Malaysia ACTRN12620000737932, Good-NIGHT COVID, U1111-1252-7005 Phase Not Applicable Not yet recruiting 1 250 Dr Thomas Daniels 2020-08-06
Evaluation of the effect of chronic use of Antimalarials on the frequency of infection with the New Corona Virus 2019 (Severe Acute Respiratory Syndrome Coronavirus 2 - SARS-CoV-2) in patients with Immunomedical Rheumatic Diseases Connective tissue disease, Coronavirus disease 19 infection, Inflammatory disease, Myopathy, Osteoarthritis, Rheumatoid arthritis, Scleroderma, Sjoegrens syndrome, Systemic lupus erythematosus Chloroquine alone, Hydroxychloroquine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sociedade Brasileira de Reumatologia Ministério da Saúde – Departamento de Ciência e Tecnologia (MS-DECIT) Brazil 30246120.3.1001.5505, RBR-9ktwx6 Phase Not Applicable Recruiting 1 9000 Cláudia diniz lopes marques, Marcelo Pinheiro 2020-08-05
Status of management of surgery in Beijing during COVID-1 Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Beijing Friendship Hospital, Capital Medical University ChiCTR2000033198 Phase Not Applicable Recruiting 0 500 Kai Pang, Zhongtao Zhang 2020-08-04
Intranasal Heparin Tolerability Study Coronavirus disease 19 infection heparin sodium alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Mississippi US 2020-08-31 2020-09-30 INTRANASAL HEPARIN, NCT04490239 Phase 0 Clinical Not yet recruiting 1 1 Month 6 Bill Gurley, PhD, Joshua S Sharp, PhD, Joshua Sharp 2020-08-05
Characteristics and Outcomes of Gastrointestinal Manifestations of COVID-19 Coronavirus disease 19 infection, Gastrointestinal disease Assiut University Egypt 2020-07-31 2020-09-30 COVID GASTRO INTESTINAL, NCT04490772 Phase Not Applicable Not yet recruiting 1 2 Months 200 Haidi Karam 2020-08-04
YCOVID: Rapid Diagnostic Test for COVID-19 Based on Antibody Detection Coronavirus disease 19 infection ELISA test alone, rapid diagnostic test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Corporacion Parc Tauli Spain 2020-06-22 2020-09-30 2020/587, NCT04490837, YCOVID Phase Not Applicable No longer recruiting 1 3 Months 3500 Juan Francisco Delgado de la Poza 2020-08-04
Comprehensive mental and physical health assessment and intervention studies for novel coronavirus pneumonia (COVID-19) patients Coronavirus disease 19 infection, Viral pneumonia mental and physical health assessment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Wuhan Jinyintan Hospital China 2020-07-20 2022-03-31 ChiCTR2000035060 Phase Not Applicable Not yet recruiting 1 20 Months 2000 LIU YING, Liu Zhengkui, Wang Qiongya 2020-08-05
Inhalation of KELEA Excellerated Water in Covid-19 Infected Individuals Coronavirus disease 19 infection KELEA excellerated water intake alone Institute of Progressive Medicine US 2020-08-01 2020-11-30 KELEA-1, NCT04490824 Phase Not Applicable Recruiting 1 4 Months 100 W John Martin, MD, PhD 2020-07-31
An Observational Study of Integrated Chronic Pain Management in a Community Health Center Coronavirus disease 19 infection, Pain NextGen (NextGen EHR) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Washington University School of Medicine, US Logan University (US) US 2018-08-01 2020-05-25 NCT04490291, RD04240531 Phase Not Applicable Completed 1 21 Months 42 Chrisotpher Prater 2020-07-31
AmbcoviDD19: Assessment of disease progression, infection chains and seroprevalence of Covid-19 infections in Saxony Coronavirus disease 19 infection University Hospital Carl Gustav Carus Germany 2020-04-09 AmbcoviDD19, BO-EK-137042020, DRKS00022549 Phase Not Applicable Recruiting 1 250 Jakob Armann 2020-07-31
Efficacy and outcomes of Lian-Hua Qing-Wen capsule in the treatment of novel coronavirus pneumonia (COVID-19): a medical records based retrospective study Coronavirus disease 19 infection, Viral pneumonia Lian-Hua Qing-Wen capsule alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) 920th Hospital of Jiont Logistic Support Force,Chinese PLA China 2020-02-04 ChiCTR2000035046 Phase Not Applicable Recruiting 1 147 Liu Zhiyong, Zhang Shurong 2020-08-03
A clinical trial of allogeneic bone marrow-derived mesenchymal stem cells for treatment of adult COVID-19 patients Coronavirus disease 19 infection allogeneic bone marrow-derived mesenchymal stem cells, Stemedica Cell Technologies alone Promedica Inc, Stemedica Cell Technologies Inc Phase 2 Clinical Status not specified 0 8 2020-07-30
A phase III clinical trial of COVID-19 vaccine for potential treatment of COVID-19 infection Coronavirus disease 19 infection SARS-CoV-2 vaccine (COVID-19), Sanofi Pasteur/GlaxoSmithKline alone COVID19 Spike glycoprotein modulator GlaxoSmithKline plc, Sanofi SA 2020-12-31 Phase 3 Clinical Planned 0 2020-08-04
A phase I/II clinical trial of COVID-19 vaccine for potential treatment of COVID-19 infection Coronavirus disease 19 infection SARS-CoV-2 vaccine (COVID-19), Sanofi Pasteur/GlaxoSmithKline alone COVID19 Spike glycoprotein modulator GlaxoSmithKline plc, Sanofi SA 2020-09-30 Phase 1/Phase 2 Clinical Planned 0 2020-08-04
FLARE: Favipiravir +/- Lopinavir: A RCT of Early Antivirals Coronavirus disease 19 infection favipiravir alone, lopinavir + ritonavir alone, favipiravir plus lopinavir + ritonavir HIV protease inhibitor, RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University College London, University of London LifeArc UK 2020-08-17 2021-03-01 132084, 2020-002106-68, CTU/2020/354, FLARE, NCT04499677 Phase 2a Clinical Not yet recruiting 1 6 Months 240 David Lowe, FLARE Trial Team UCL CCTU 2020-08-06
PERUCONPLASMA: Evaluating the Use of Convalescent Plasma as Management of COVID-19 Coronavirus disease 19 infection, Respiratory insufficiency convalescent plasma alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidad Peruana Cayetano Heredia Peru 2020-07-27 2020-12-31 20997, NCT04497324, PER-016-20, PERUCONPLASMA Phase 2b Clinical Not yet recruiting 1 5 Months 100 Fiorella Krapp Lopez, MD, MSc, Patricia Garcia Funegra, MD 2020-08-06
AP-PEDCOVID: Seroprevalence and Immunoprotection Against COVID-19 in Parisian Children Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Assistance Publique Hopitaux de Paris France 2020-04-09 2021-12-31 AP-PEDCOVID, HNECKERNM, NCT04490811 Phase Not Applicable Recruiting 2 20 Months 800 Isabelle Sermet-Gaudelus, Professor, Philippe Tourenne, SERMET Isabelle, Professor 2020-07-31
Convalescent plasma as treatment for COVID-19 Coronavirus disease 19 infection convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) SEGURO SOCIAL DE SALUD- ESSALUD Peru 2020-06-01 ESSALUD-012020, PER-013-20 Phase 2 Clinical Not yet recruiting 1 192 ARTURO SAGASTEGUI SOTO, AUSBERTO CHUNGA CHUNGA, CHIRISTIAN Villanueva GONZALES, IBETH MELANIA NEYRA VERA, JORGE MAGUIÑA QUISPE, LEDA YAMILEE HURTADO ROCA, PERCY SOTO BECERRA, ROGER VLADIMIR ARAUJO CASTILLO 2020-07-31
What Are the Clinical Factors Associated With a Significant Pain Reduction Following Physiotherapy in Patients With Temporomandibular Disorders Coronavirus disease 19 infection, Temporomandibular joint syndrome Physiotherapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Italian Institute Stomatologico The University of Birmingham Italy 2019-06-14 2020-12-31 NCT03990662, PREDICTORSOUTCOMETMD2019GA Phase Not Applicable Recruiting 1 18 Months 100 Giacomo Asquini 2020-08-01
The Fenland COVID Study: A study to understand the progression and early signs of COVID-19 infection Coronavirus disease 19 infection smartphone app alone Huma University of Cambridge 2020-07-23 The Fenland COVID Study Phase Not Applicable Recruiting 0 2020-07-30
A clinical trial of anti-SARS-CoV-2 spike protein mAb (COVID-19), Adagio Therapeutics for the potential treatment and prevention of SARS-CoV-2 infection (COVID-19) Coronavirus disease 19 infection anti-SARS-CoV-2 spike protein mAb (COVID-19), Adagio Therapeutics alone COVID19 Spike glycoprotein modulator Adagio Therapeutics 2020-12-31 Phase Not Applicable Planned 0 2020-07-30
A randomized, double-blind, placebo-controlled, pilot study to evaluate the feasibility of RTB-101 compared to placebo for COVID-19 post-exposure prophylaxis in older adults Coronavirus disease 19 infection dactolisib alone Phosphoinositide 3-kinase inhibitor, mTOR complex 1 inhibitor, mTOR complex 2 inhibitor Aged Adults (65-79 yrs), Elderly Adults (80 and over) resTORbio Inc Harvard Medical School, National Institute on Aging, University of Connecticut Health Center Phase Not Applicable Planned 0 60 2020-07-30
Serological Surveillance for COVID-19 in Central North Carolina Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute Of Environmental Health Sciences National Institutes of Health Clinical Center US 2020-08-11 2022-06-01 20-E-0143, 200143, NCT04490174 Phase Not Applicable Recruiting 1 21 Months 2500 Nicole Edwards, Stavros Garantziotis, M.D. 2020-08-07
Post-ICU Follow-up in Patients With Severe SARS-CoV-2 Infection (COVID-19) Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Université De Strasbourg 2020-07-27 2021-07-27 7890, NCT04491214 Phase Not Applicable Not yet recruiting 0 12 Months 131 Walid OULEHRI 2020-08-01
SCEI: Stress Induced by the COVID-19 Pandemic and Non-confinement: Study of Anxiety Factors and Potential Effects on Immunity Anxiety disorder, Coronavirus disease 19 infection, Post traumatic stress disorder COVID-19 questionnaire alone, Experiences in Close Relationship Scale questionnaire (ECR-S) alone, Generalized Anxiety Disorder-7 (GAD 7) alone, Patient Health Questionnaire (PHQ-9) alone, Post Traumatic Stress Disorder questionnaire (PTSD-8) alone, mental health questionnaire alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire de Saint Etienne UK, France 2020-07-31 2020-12-31 20CH129, NCT04491071, SCEI Phase Not Applicable Not yet recruiting 2 5 Months 405 Claude LAMBERT, MD PhD HDR, Fleur PETIT, CRA 2020-08-01
This is the comparative study between two protective boxes which can be used by the doctors while managing critical COVID 19 patients in addition to personal protective equipment Coronavirus disease 19 infection, Surgical procedure new modified aerosol box alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute Of Medical Sciences, Rishikesh India 2020-08-03 CTRI/2020/07/026790 Phase Not Applicable Not yet recruiting 1 21 Dr Ankit Agarwal, Dr Mohammad Hashim 2020-08-05
A clinical trial of universal SARS-CoV-2 vaccine (peptide vaccine, COVID-19), MyNEO for the potential prevention of COVID-19 Coronavirus disease 19 infection universal SARS-CoV-2 vaccine (peptide vaccine, COVID-19), MyNEO alone COVID19 Spike glycoprotein modulator, COVID19 envelope small membrane protein modulator, COVID19 nucleoprotein modulator, COVID19 structural glycoprotein modulator MyNEO Phase Not Applicable Planned 0 2020-08-01
HemoCov: COVID-19 Quarantine on Musculoskeletal Status in Hemophilia Bleeding, Coronavirus disease 19 infection, Factor IX deficiency, Factor VIII deficiency, Joint disease, Pain Healthy volunteers accepted, Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidad Europea De Madrid Spain 2020-07-01 2020-07-29 HEMOCOV, HemoCov, NCT04491318 Phase Not Applicable Recruiting 1 27 Rubén Cuesta-Barriuso, PhD 2020-07-31
A single-center, cohort observational study to evaluate clinical characteristics and short-term outcome of kidney transplant patients admitted for SARS-CoV2 pneumonia Coronavirus disease 19 infection, Pneumonia anti-viral therapy alone, hydroxychloroquine alone, methylprednisolone alone, tocilizumab alone Azienda Ospedaliera Spedali Civili di Brescia, Universita degli Studi di Brescia Phase Not Applicable Status not specified 0 20 2020-07-31
VESTA: Effectiveness of a Novel Respirator With Chitosan Nanoparticles Coronavirus disease 19 infection VESTA respirator alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) University of Brasilia Centro de Pesquisa em Biotecnologia Ltda, Hospital Regional da Asa Norte, Universidade Estadual de Campina, University Hospital of Brasilia Brazil 2020-08-30 2021-07-31 32862320.0.0000.0030, NCT04490200, VESTA, VESTA TRIAL Phase Not Applicable Not yet recruiting 1 11 Months 1000 Aline M Toledo, PhD, Glécia V Silva Luz, PhD, Graziella A Joanitti, PhD, Henry M Peixoto, PhD, Marcella L Brettas Carneiro, PhD, Mario Fleury Rosa, PhD, Rodrigo L Carregaro, PhD, Suelia S Fleury Rosa, PhD 2020-08-04
A clinical trial of SARS-CoV-2 vaccine program (COVID-19), Avidin for the prevention of Covid-19 Coronavirus disease 19 infection SARS-CoV-2 vaccine program (COVID-19), Avidin alone COVID19 Spike glycoprotein modulator Avidin Biotechnology Phase Not Applicable Planned 0 2020-08-04
Umbilical Cord Tissue (UC) Derived Mesenchymal Stem Cells (MSCs) Versus Placebo to Treat Acute Pulmonary Inflammation Due to COVID-19 Coronavirus disease 19 infection, Hypoxia, Lung inflammation, Respiratory distress syndrome umbilical cord-derived mesenchymal stem cells (iv, COVID-19/lung inflammation/acute lung injury/ADRS), University of Miami alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) KCNQ2 Cure Alliance Foundation, University of Miami, University of Miami Miller School of Medicine US 2020-08-01 2024-06-01 20200575, NCT04490486 Phase 1 Clinical Not yet recruiting 3 46 Months 21 Camillo Ricordi, M.D, Joshua M Hare, MD, Yvenie Desire, BS 2020-08-04
Simulation study of tracheal intubation through an aerosol-box assuming COVID-19 Coronavirus disease 19 infection AirWay Scope S-100 (Pentax) alone, Laerdal Airway Management Trainer (Laerdal Medical Japan Ltd) alone, Macintosh laryngoscope (Riester) alone, McGRATH MAC (Aircraft Medical Ltd) alone, SealGuard Evac cuffed tracheal tube (Covidien) alone, Shiley Intubation Stylet (Covidien) alone, Splash Guard CG:SGCG aerosol box alone, mask ventilation alone, tracheal intubation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tokyo Women's Medical College Japan 2020-05-01 UMIN000040289 Phase Not Applicable No longer recruiting 1 30 Idei Masafumi, Masafumi Idei 2020-07-31
On-line Neuromuscular Exercise and Education for Knee Osteoarthritis Coronavirus disease 19 infection, Osteoarthritis GLA:D exercise and education program alone, on-line NEMEX-TJR neuromuscular exercise alone, on-line education alone, on-line stretching exercise alone, on-line warm-up exercise alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Slagelse Hospital Region Zealand Denmark 2020-06-12 2021-12-31 J.NR. 20-000013, NCT04437134, SLAGELSEH Phase Not Applicable Recruiting 4 18 Months 500 Pætur M Holm, PhD, Søren T Skou, Professor 2020-07-31
ALADDIN: Quality of Life and Addiction Among Hospital Night Workers Coronavirus disease 19 infection, Drug dependence, Post traumatic stress disorder, Psychiatric disorder Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Universite Denis Diderot Assistance Publique Hopitaux de Paris, INSERM France 2020-06-15 2023-06-01 ALADDIN, ALADDIN-QOLHOSPWORK, NCT04291534 Phase Not Applicable Not yet recruiting 1 35 Months 1800 Dr Martin Duracinsky 2020-08-02
Esophagogastroduodenoscopy (EGD) is an Aerosol-generating Procedure: Proof of Concept Study Coronavirus disease 19 infection, Gastrointestinal disease esophagogastroduodenoscopy alone Chinese University of Hong Kong Hong Kong 2020-05-07 2021-01-31 2020.200, NCT04400734 Phase Not Applicable Recruiting 1 8 Months 60 Chan Shannon Melissa, Philip Chiu, FRCSEd, Shannon Chan, FRCSEd 2020-08-02
A trial to evaluate ADEXUSDx COVID-19 Antibody Test to measure the presence of SARS-CoV-2 antibodies for the diagnosis of COVID-19 Coronavirus disease 19 infection ADEXUSDx COVID-19 Antibody Test alone NOWDiagnostics Inc Phase Not Applicable Planned 0 2020-07-30
CMDA-SURVEY2: National Survey of the Impact of COVID-19 Pandemics Coronavirus disease 19 infection customized questionnaire alone, social software WeChat alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry Peking Union Medical College Hospital China 2020-07-27 2020-09-27 CMDA-SURVEY2, CMDA-SURVEY2, NCT04491201 Phase Not Applicable Recruiting 1 2 Months 6000 Lei Li, M.D., Lei Li, MD 2020-08-02
Assessment of the Psychosocial Impact of the COVID-19 Pandemic on the MD Anderson Cancer Center Workforce Coronavirus disease 19 infection online questionnaire alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) MD Anderson Cancer Center National Cancer Institute US 2020-05-18 2021-04-30 2020-0428, NCI-2020-04259, NCT04491292 Phase Not Applicable Recruiting 1 11 Months 20000 Priya R Bhosale, Priya R. Bhosale 2020-08-02
A Qualitative study regarding stress and coping in Front-line Health Care Doctors at a tertiary-care hospital Acute stress disorder, Coronavirus disease 19 infection, Psychiatric disorder depth interview alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) B. J. Medical College, Pune India 2020-08-17 CTRI/2020/07/026788 Phase Not Applicable Not yet recruiting 1 20 Dr Ivan Stanley Netto 2020-08-04
Global Assessment of Acute and Chronic Kidney Disease Incidence and Outcomes in Patients With COVID-19 Infection Coronavirus disease 19 infection, End stage renal disease, Renal disease, Renal injury Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of California San Diego India, Chile, US, Canada, Bolivia, UK 2020-05-05 2023-03-31 000295, NCT04491227 Phase Not Applicable Recruiting 12 34 Months 2000 Ravindra L Mehta 2020-08-01
R4VaD: Understanding cognitive decline after stroke and the impact of COVID-19 Cognitive disorder, Coronavirus disease 19 infection, Stroke, Vascular dementia Blood analysis alone, Routine bran imaging (CT or MRI) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Academic and Clinical Centre Office for Research and Development [ACCORD], UK Alzheimers Society, British Heart Foundation, The Stroke Association, United Kingdom UK 2018-07-01 2023-06-30 AC18001, ISRCTN18274006, R4VaD Phase Not Applicable Recruiting 10 60 Months 2000 Prof Wardlaw 2020-08-06
INHALE: Inhale work package 3 - rapid versus standard testing to diagnose lung infections in intensive care, including COVID-19 observational sub-study Coronavirus disease 19 infection, Lower respiratory tract infection, Viral pneumonia BioFire FilmArray alone, standard care alone University College London NIHR Central Commissioning Facility UK 2018-10-01 2021-06-30 41211, INHALE, ISRCTN16483855 Phase Not Applicable Recruiting 12 33 Months 466 Dr Enne 2020-08-03
postcorona: Postcorona care Coronavirus disease 19 infection, Heart disease, Inflammatory disease, Lung disease, Psychotic disorder, Pulmonary fibrosis Leiden University Medical Center Netherlands 2020-07-13 2020-12-22 NL8775, postcorona Phase Not Applicable Recruiting 1 5 Months 90 Geert Groeneveld 2020-07-31
A clinical trial to study the effects of an Ayurvedic medicine, Haldi 30 (Turmeric extract) drops in patients with Corona virus infection Coronavirus disease 19 infection Haldi 30 alone, Standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sahyadri Hospitals India 2020-08-03 CTRI/2020/07/026841 Phase 2 Clinical Not yet recruiting 2 260 Dr Sarang Phadke 2020-08-02
Determination of dandelion capsule on patient with COVID-19 virus Coronavirus disease 19 infection Variable regimens including Dandelherb (Booali Daro Pharmaceutical Factory) , dexamethasone , interferon beta-1b , remdesivir COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ghoum University of Medical Sciences Iran 2020-07-26 IR.MUQ.REC.1399.148, IRCT20180513039641N2 Phase 3 Clinical Recruiting 1 80 Ehsan Sharifipour, Hoda Abolhasani, Reihaneh Tabaraie, hoda Abolhasani 2020-08-03
Evaluating the effects of intravenous immunoglobulin (IVIG) in COVID-19 patients Coronavirus disease 19 infection Variable regimens including IVIG (Biotest) , hydroxychloroquine (Tehran Daroo) , lopinavir + ritonavir (Hetero Labs Limited) Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Shaheed Beheshti Medical University Iran 2020-07-09 IR.SBMU.NRITLD.REC.1399.143, IRCT20151227025726N20 Phase 2/Phase 3 Clinical Recruiting 1 80 Afshin Zarghi, Farzaneh Dastan, Payam Tabarsi, Zahra Mirshafiei Langari 2020-08-02
Safety and Efficacy of EDP-1815 in the Treatment of Patients Hospitalized With COVID-19 Infection Coronavirus disease 19 infection EDP-1815 alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Evelo Biosciences Inc, Robert Wood Johnson University Hospital, Rutgers University US 2020-08-07 2020-12-21 EDP1815-205, NCT04488575 Phase 2 Clinical Not yet recruiting 4 4 Months 60 Daniela Walker, Deborah McCloskey, Douglas Maslin, MD, Keith Guevarra, MD, Randall Teeter, Reynold A. Panettieri, Jr., M.D 2020-07-31
PERSO-COVID: Medical and Serological Follow-up of the Staff of the Paris Saint-Joseph Hospital Group Infected With Severe Acute Respiratory Syndrome Coronavirus 2. Coronavirus disease 19 infection Serology test follow-up alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Groupe Hospitalier Paris Saint-Joseph France 2020-07-01 2021-12-31 NCT04488484, PERSO-COVID, PERSO-COVID Phase Not Applicable No longer recruiting 1 18 Months 450 2020-07-31
STAND UP to SARS-CoV-2 (COVID-19): Using Behavioural Economics to Reduce Sedentary Behaviour in At-home Office Workers Coronavirus disease 19 infection Long-List Choice Group alone, No Choice Group alone, Short List Choice Group alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Western Ontario Duke University Canada 2020-09-30 2020-12-31 116127, NCT04488796 Phase Not Applicable Not yet recruiting 1 3 Months 135 Kirsten Dillon, MA, Marc Mitchell, PhD, Marc Mittchell, PhD 2020-07-31
COVAP: Pathogens Involved in Secondary Infections During Severe Forms of Covid-19 Pneumonia Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Groupe Hospitalier Paris Saint-Joseph Centre Hospitalier Victor Dupouy France 2020-05-06 2020-11-30 COVAP, COVAP, NCT04488510 Phase Not Applicable No longer recruiting 1 6 Months 150 2020-08-04
DECOR-19: Delayed Colorectal Cancer Care During Coronavirus Disease (COVID-19) Pandemic Colorectal tumor, Coronavirus disease 19 infection Treviso Regional Hospital Universita degli Studi di Roma La Sapienza, Universita' Degli Studi "Magna Graecia" Di Catanzaro Italy 2020-05-20 2020-06-10 DECOR-19, NCT04488549, TREVISO Phase Not Applicable Completed 1 1051 Gaetano Gallo, Gian Luca Di Tanna 2020-07-30
Can Remote Photoplethysmography Be Used for Contactless Vital Sign Acquisition in a Healthcare Setting? A Prospective, Comparative Study Coronavirus disease 19 infection Masimo Radical 7 alone, Welch Allyn Connex Vital Signs Monitor alone, Welch Allyn Vital Signs Monitor alone, remote photoplethysmography (rPPG) vital sign acquisition alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Lady Davis Institute Carebook Technologies Inc Canada 2020-08-01 2020-11-30 2021-2376, NCT04489407 Phase Not Applicable Not yet recruiting 1 4 Months 350 Noura Hassan, Noura Hassan, MD, MPH 2020-07-29
Study of skin, hair and nail changes after COVID 19 illness Coronavirus disease 19 infection, Dermatological disease Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gujarat Cancer Society Medical college hospital and research centre India 2020-08-24 CTRI/2020/07/026821 Phase Not Applicable Not yet recruiting 1 500 Dr Nayan H Patel 2020-08-03
BET: A NIAID-sponsored Big Effect trial (BET) to assess the combination of lenzilumab and remdesivir on treatment outcomes versus placebo and remdesivir in hospitalized COVID-19 patients Coronavirus disease 19 infection lenzilumab plus remdesivir COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, GM-CSF ligand inhibitor, Immunoglobulin G1 modulator, Immunoglobulin kappa modulator, RNA polymerase modulator Humanigen Inc, National Institute of Allergy and Infectious Diseases BET Phase Not Applicable Status not specified 0 2020-07-29
Curcumin for COVID-19 Pre Exposure Prophylaxis Coronavirus disease 19 infection curcumin alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute Of Medical Sciences, Rishikesh India 2020-08-09 CTRI/2020/07/026820 Phase 4 Clinical Not yet recruiting 1 200 Rohit Walia 2020-07-30
Comparison of two different types of simple non-invasive oxygen therapy devices in coronavirus lung infection Coronavirus disease 19 infection, Lung infection, Respiratory failure, Viral pneumonia High Flow Nasal Oxygen alone, Optiflow alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Medical Sciences India 2020-07-27 CTRI/2020/07/026835 Phase 3 Clinical Not yet recruiting 1 100 Dalim Kumar Baidya 2020-07-30
A clinical trial of anti-coronavirus vaccine,State Research Center of Virology and Biotechnology VECTOR for the treatment of COVID-19 Coronavirus disease 19 infection anti-coronavirus vaccine,State Research Center of Virology and Biotechnology VECTOR alone State Research Center of Virology and Biotechnology VECTOR Phase Not Applicable Not yet recruiting 0 2020-07-29
Survival and 30-days Hospital Outcome in COVID-19 Patients in Upper Egypt Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Assiut University Egypt 2020-03-15 2020-07-01 ASSIUTU17, NCT04488588 Phase Not Applicable Completed 2 3 Months 1064 Aliae Mohamed-Hussein, MD 2020-07-30
Open Skies: Use of new technology for rapid detection of SARS-CoV2 Coronavirus disease 19 infection NAOR platform alone, Terasystem Breath Analyser test alone, VIRION test alone, Voice Pattern test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry Defence Research & Development Organisation Defence Institute of Physiology and Allied Sciences (DIPAS) India 2020-08-05 CTRI/2020/07/026843, Open Skies, Open Skies Phase Not Applicable Recruiting 4 10000 Dr Ambuj Garg, Dr Anil Gurtoo, Dr Desh Deepak, Dr Naresh Kumar, Dr Reena Mariya 2020-07-31
Nimesulide in COVID-19 infection Coronavirus disease 19 infection, Viral pneumonia Variable regimens including azithromycin , enoxaparin sodium , nimesulide , sucralfate Cyclooxygenase 2 inhibitor, Low molecular weight heparin Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shaheed Zulfiqar Ali Bhutto Medical University Islamabad Iran 2020-07-28 IRCT20200723048178N1, No.F.1-1//2015/ERB/SZABMU/605 Phase 2 Clinical Recruiting 1 60 Ahmed Farhan 2020-07-30
REaCHing to you with listening ears: A friendly telephonic interaction program for the DDU-GKY members Coronavirus disease 19 infection Assertive linkage with community resources alone, Proactive Engagement and Crisis Intervention alone, Problem-solving oriented supportive therapy alone Healthy volunteers accepted, Young Adults (18-44 yrs) Rajagiri college of Social Sciences UK India Education Research Initiative (UKIERI) India 2020-08-07 CTRI/2020/07/026834 Phase Not Applicable Not yet recruiting 26 1480 Dr Saju M D 2020-07-30
Artificial intelligence and machine learning for Covid 19 Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Visvesvaraya Technological University (VTU) India 2020-07-13 CTRI/2020/07/026832 Phase 1 Clinical Not yet recruiting 1 100 Dr DwajaniS, Dr Mukesh PR 2020-07-30
Sildenafil in COVID-19 Coronavirus disease 19 infection, Ischemia sildenafil alone PDE 5 inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidad Andres Bello Hospital Naval Almirante Nef Chile 2020-08-31 2021-03-31 NCT04489446, UNAB-003 Phase 1/Phase 2 Clinical Not yet recruiting 1 7 Months 40 Cesar Reyes, MD, Dominique Boisier, MD, Eduardo Labarca, MD, Felipe M Martinez, MD, MSc, Felipe Martinez, MD, MSc, Jaime Vidal, MD, Jorge Vega, MD, Mario Santamarina, MD, Miguel Gutierrez, MD, Monica Gutierrez, MD, Nicole Retamal, Roberto Contreras, MD, Sebastian Ahumada, MD 2020-07-31
COVID-19: Attitude Toward Quarantine Coronavirus disease 19 infection Taibah University Saudi Arabia 2020-07-15 2020-08-15 55834, NMRR-20-1574-55834 Phase Not Applicable Status not specified 1 1 Month Noordin othman, Suhana Jawahir 2020-07-30
Hydroxychloroquine for COVID-19 Coronavirus disease 19 infection hydroxychloroquine alone National Institutes of Health Malaysia Malaysia 2020-08-03 2020-09-03 54669, NMRR-20-1593-54669 Phase Not Applicable Status not specified 1 1 Month dr Nor Asiah Muhamad 2020-07-30
A study to assess the effectiveness of Ayurvedic formulation Guduchi Ghan vati in Covid-19 cases Coronavirus disease 19 infection Guduchi Ghan Vati alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ministry of Ayush India 2020-07-28 CTRI/2020/07/026840 Phase 2 Clinical Recruiting 1 30 Dr Nitin Ujjaliya, Dr Vivek Khare, Prof Umesh Shukla 2020-08-02
Facts on Bear Bile Use in Coronavirus Disease 2019 (COVID-19) Coronavirus disease 19 infection Bear Bile alone Institute For Medical Research (Inc In Malaysia) Malaysia 2020-04-01 2020-06-01 55957, NMRR-20-1604-55957 Phase Not Applicable Status not specified 1 2 Months Ms. Lim Xin Yi, Terence Tan Yew Chin 2020-07-31
LUS: lung ultrasound Coronavirus disease 19 infection ultrasound alone Hospital Sungai Buloh Malaysia 2020-07-27 2020-12-31 55711, NMRR-20-1599-55711 Phase Not Applicable Status not specified 1 5 Months Dr ELISA AUDREY EDDIE, Dr Mahathar Abdul Wahab 2020-08-02
Antibody, RT-PCR, COVID-19 Coronavirus disease 19 infection RT-PCR alone Hospital Sungai Buloh Malaysia 2020-07-31 2021-07-30 55832, NMRR-20-1598-55832 Phase Not Applicable Not yet recruiting 1 12 Months DR THARMINI A/P RAVI, Dr Suresh Kumar 2020-07-31
A phase II/III clinical trial of CodaVax-COVID for the prevention of Covid-19 Coronavirus disease 19 infection CodaVax-COVID alone Codagenix Inc, Serum Institute of India Ltd hVIVO plc Phase 2/Phase 3 Clinical Planned 0 2020-07-29
A trial to evaluate rigosertib for the treatment of patients with COVID-19 disease Coronavirus disease 19 infection rigosertib sodium (iv, MDS/solid tumors), Onconova/SymBio alone AKT protein kinase inhibitor, BCL2L11 gene stimulator, Cyclin D1 inhibitor, Cyclin-dependent kinase-1 inhibitor, Jun N terminal kinase modulator, MAP kinase inhibitor, Phosphoinositide 3-kinase inhibitor, Polo-like kinase 1 inhibitor, Raf protein kinase inhibitor Onconova Therapeutics Inc Phase Not Applicable Planned 0 2020-07-29
HOMECOMIN': Home Monitoring and Evaluation After Admission for COVID-19 in the Netherlands Coronavirus disease 19 infection, Pulmonary fibrosis spirometer (Spirobank Smart) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Erasmus University Medical Center Rotterdam Dutch Society of Physicians for Pulmonology and Tuberculosis, Leiden University Medical Center, VU University Medical Center Netherlands 2020-05-08 2021-12-31 HOMECOMIN', MEC-2020-0318, NCT04488562 Phase Not Applicable Recruiting 3 19 Months 150 C.C. Moor, drs, Cintha Klop, E.J. Nossent, Esther van der Kaay, G Nakshbandi, G. Nakshbandi, drs, Gizal Nakshbandi, drs, J.J.M. Geelhoed, dr, M.S. Wijsenbeek, dr 2020-07-30
Impact of Isolation in Patients With IBD During the COVID-19 Crisis Coronavirus disease 19 infection, Inflammatory bowel disease Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sheffield Teaching Hospitals NHS Foundation Trust UK 2020-06-30 2022-06-30 NCT04488471, STH21414 Phase Not Applicable Recruiting 1 24 Months 232 Alan Lobo, MD, Luke Barron, MSc 2020-07-30
Clinical trial of Annual SZ drug in Covid-19 Coronavirus disease 19 infection Anval SZ plus azithromycin Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Shaheed Beheshti Medical University Iran 2020-06-09 IR.SBMU.RETECH.REC.1399.158, IRCT20200607047682N1 Phase 2/Phase 3 Clinical No longer recruiting 1 60 Afshin Zarghi, Hamid Chegini, Mohammad Farhbakhsh, Zuhair Sarraf 2020-07-30
Evaluation of the efficacy and safety of inhaled magnesium sulfate in combination with standard treatment in Covid-19 patients Coronavirus disease 19 infection magnesium sulfate alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shaheed Beheshti Medical University Iran 2020-07-27 IR.SBMU.NRITLD.REC.1399.148, IRCT20191211045691N1 Phase 3 Clinical Recruiting 1 100 Guitti Pourdowlat, Seyed Ruhollah Mousavinasab, ‪Parissa Farnia 2020-07-30
Tele-health Enabled Clinical Trial for COVID19 Coronavirus disease 19 infection, Immune disorder Doctella device alone, cholecalciferol alone, telehealth monitoring alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospitals of Cleveland Northwestern University US 2020-08-01 2021-08-01 NCT04489628, STUDY20200461 Phase 1/Phase 2 Clinical Not yet recruiting 1 12 Months 110 Amanda Davies, Kevin Cooper, MD, Kurt Lu, MD, Lyndsey O'Hara, BSN, Wesley Yu, MD 2020-08-04
CoronaKids: CoronaKids - Epidemiological data acquisition SARS-CoV2/Covid-19 Coronavirus disease 19 infection epidemiological data analysis alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Univ Witten / Herdecke Germany 2020-03-27 61/2020, CoronaKids, DRKS00021229 Phase Not Applicable Recruiting 1 900 Stefan Wirth 2020-07-30
CCHROMO: COVID19 Chronic Morbidity: Follow-up of patients with COVID19 and non-COVID19 pneumonia with respect to clinical status, pulmonary function and radiologic findings Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitätsklinikum Frankfurt Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie Hannover Medical School Germany 2020-07-27 20-748, CCHROMO, DRKS00022475 Phase Not Applicable Not yet recruiting 1 500 Gernot Rohde 2020-08-06
CovPall: Improving palliative care for people affected by the COVID-19 pandemic by sharing learning - the national and international response Coronavirus disease 19 infection palliative care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) King's College London Cicely Saunders International, Kings College Hospital NHS Trust, National Institute for Health Research (NIHR) Portugal, UK, Canada, Ireland, Switzerland, Australia, Netherlands, India, Argentina, Brazil, South Africa 2020-04-01 2021-04-24 CovPall, ISRCTN16561225, LRS-19/20-18541, IRAS 282824 Phase Not Applicable Recruiting 13 12 Months Miss Cripps 2020-07-30
Study of Shreepad Shree Vallabh SSV Formulation in management of COVID-19 Coronavirus disease 19 infection SSV Formulation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) SSV Phytopharmaceuticals India 2020-08-05 CTRI/2020/07/026839, SSV-SF-07/2020 Phase 3 Clinical Not yet recruiting 1 150 Dr Sagar Mandlik, Dr Yogesh Dound 2020-07-30
PREDISCAN: Predicting the Progression to Chronic Fibrosis of Lung Lesions Related to Covid-19 Infection From Chest CT Images Coronavirus disease 19 infection, Pulmonary fibrosis, Viral pneumonia Chest CT scan alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Association Marie Lannelongue France 2020-06-08 2021-11-08 2020-A01322-37, NCT04483752, PREDISCAN Phase Not Applicable Recruiting 3 17 Months 100 CAROLINE CARAMELLA, MD, Corinne Institut Gustave Roussy (IGR), MD, Marie De Torcy 2020-07-30
Antibody response to COVID-19 in health care workers Coronavirus disease 19 infection LIAISON SARS-CoV-2 S1/S2 IgG test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) DiaSorin Healthcare India Private Limited, Ortho Clinical Diagnostics India Private Limited India 2020-08-04 Phase Not Applicable Not yet recruiting 1 Dr Smita Sarma 2020-07-29
Effect of COVID - 19 pandemic researchers Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Manipal Academy of Higher Education India 2020-08-10 CTRI/2020/07/026836 Phase Not Applicable Not yet recruiting 1 1850 Elsa Sanatombi Devi 2020-07-30
Encouraging behavior to reduce the spread of COVID-19 Coronavirus disease 19 infection Impact Others, Cooperative Linear Production (IOCLP) message alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Yale University US 2020-05-01 2020-07-24 1312013102, ISRCTN17896927 Phase Not Applicable Completed 2 2 Months 3000 Prof Huber 2020-07-30
N-terminal Pro B-type Natriuretic Peptide and Vitamin D Levels as Prognostic Markers in COVID-19 Pneumonia Coronavirus disease 19 infection, Hypoxia, Respiratory failure, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cairo University Kasr El Aini Hospital Egypt 2020-07-01 2021-01-01 2020-7-1, NCT04487951 Phase Not Applicable Recruiting 1 6 Months 100 Akram Abdelbary, Prof., Noha A. Radwan, Noha A. Radwan, Lecturer, Noha A. Radwan, Lecturer of Chemical pathology, Noha Radwan, Lecturer, Yasmine Elshiwy, Ass. Prof. 2020-08-05
Complementary Intervention for COVID-19 Coronavirus disease 19 infection conventional therapy alone, Boswellia Serrata gum plus Licorice extract Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Assiut University Egypt 2020-01-01 2021-01-31 0925-0586, NCT04487964 Phase Not Applicable Recruiting 1 13 Months 70 Adel A. Gomaa, Ph.D., Adel Gomaa, Ph.D., Hamdy S Mohamed, MD, Mostafa Hamdy, Ph.D. 2020-07-30
SARS-CoV2 (COVID-19) Seroepidemiological Transplanted Subjects (Kidney, Kidney-pancreas, Pancreas, Langerhans Islets) Coronavirus disease 19 infection, Kidney transplantation, Pancreas transplantation Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) IRCCS San Raffaele Italy 2020-07-15 2021-01-15 COVID-SIERO TRAPIANTI, NCT04487197 Phase Not Applicable Recruiting 1 6 Months 300 Antonio Secchi, MD, Federica Pazzi, Paola Maffi, Rossana Caldara 2020-08-05
A Phase I, Prospective, Open-labeled Study to Evaluate the Safety and Immunogenicity of MVC-COV1901 Coronavirus disease 19 infection MVC-COV1901 alone COVID19 Spike glycoprotein modulator, TLR-9 agonist Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Medigen Vaccine Biologics Corp Taiwan 2020-09-01 2021-12-31 CT-COV-11, NCT04487210 Phase 1 Clinical Not yet recruiting 1 16 Months 45 Criss Cheng, Szu-Min Hsieh, MD 2020-07-30
Respiratory Mechanics and Gas Exchange Characteristics in Patient With SARS-CoV-2 Coronavirus disease 19 infection, Respiratory distress syndrome positive end-expiratory pressure therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sanatorio Anchorena San Martin Argentina 2020-07-01 2020-10-20 10.2020, NCT04486729 Phase Not Applicable Recruiting 1 3 Months 15 Javier H Dorado, PT, Joaquin Pérez, PT, Matias Accoce 2020-07-30
Exploring the Impact of a Sleep App on Sleep Quality Coronavirus disease 19 infection, Insomnia sleep app (Pro version) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University College London University of California Los Angeles UK 2020-02-13 2020-08-15 NCT04487483, SLEEPAPPEVALUATION Phase Not Applicable No longer recruiting 1 6 Months 101 Abi Fisher 2020-07-29
DAMPEN-CI: Duvelisib Ameliorates Manifestations of Pneumonia in Established Novel Coronavirus Infection (COVID-19) Coronavirus disease 19 infection, Inflammatory disease, Viral pneumonia duvelisib alone Phosphoinositide-3 kinase delta inhibitor, Phosphoinositide-3 kinase gamma inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Emory University University of Pennsylvania, Verastem Oncology US 2020-08-31 2022-02-28 DAMPEN-CI, NCT04487886, STUDY00000701 Phase 2 Clinical Not yet recruiting 3 18 Months 80 Aneesh Mehta, MD, Edmund Waller, MD, PhD 2020-07-29
Hematology and Clinical Picture in Pediatric COVID-19 Infection Coronavirus disease 19 infection, Hematological disease Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Benha University Egypt 2020-07-26 2020-08-21 NCT04487119, RC 6-7-2020 Phase Not Applicable Not yet recruiting 1 30 Effat H Assar, MD, Rana A Khashaba, MD, Shaimaa R Abdelmaksoud, MD 2020-07-29
PLEXIT: Therapeutic Plasma Exchange (TPE) for COVID-19 Cytokine Release Storm (CRS) Coronavirus disease 19 infection, Hypoxia, Respiratory distress syndrome, Respiratory failure, Sepsis, Viral pneumonia COBE Spectra Apheresis machine version 7 (TERUMO BCT) alone, anticoagulation therapy alone, corticosteroids therapy alone, ulcer prophylaxis alone, Variable regimens including Fresh frozen Plasma (FFP) , aspirin , methylprednisolone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) United Nations International Children's Fund Pak Emirates Military Hospital Pakistan 2020-04-01 2020-06-30 NCT04485169, PLEXIT, SULTAN MEHMOOD KAMRAN Phase 2 Clinical Completed 1 3 Months 280 Imran m Fazal, FCPS, Sultan mehmood kamran 2020-07-29
A pan-India phase IV trial of itolizumab in COVID-19 patients Coronavirus disease 19 infection itolizumab alone T-cell differentiation antigen CD6 inhibitor Biocon Ltd Phase 4 Clinical Planned 0 200 2020-07-30
FERTICOVID: Presence of SARS-CoV-2 in Semen: Impact on Fertility Preservation in Male Oncological Patients? Cancer, Coronavirus disease 19 infection RT- qPCR alone, nasopharyngeal swab test alone, serological test alone Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Clermont-Ferrand Biomedicine Agency France 2020-07-10 2021-07-31 2020-A01409-30, FERTICOVID, NCT04487639, RNI 2020 BRUGNON Phase Not Applicable Recruiting 15 12 Months 250 Amélie BREBION, PharmD, Anne MAYEUR, MD, PhD, Anne-Sophie CANEPA, MD, Arthur LUTON, MD, Audrey MIRAND, PharmD, PhD, Aurélie RIVES-FERAILLE, MD, Badria BENNANI SMIRES, MD, Béatrice DELEPINE, MD, Carole Carole, MD, Caroline AIMONE VIANNA, MD, Catherine DILIGENT, MD, PhD, Catherine GUILLEMAIN, MD, Catherine PATRAT, MD, Charlotte DUPONT, MD, PhD, Charlotte MAUROY, MD, Cécile GREZE, MD, Cécile HENQUELL, PharmD, PhD, Céline BOUILLON, MD, Céline BRUNO, MD, Céline CHALAS, MD, Diane RIVET-DANON, MD, Elsa LABRUNE, MD, Emmanuel DULIOUST, MD, PhD, Fanny JUMEAU, MD, Florence BOITRELLE, MD, PhD, Florence BRUGNON, MD, PhD, Florence EUSTACHE, MD, Hanae Pons-Rejraji, PhD, Isabelle KOSCINSKI, MD, PhD, Isabelle LICHTBLAU, MD, Jacqueline LORNAGE, MD, PhD, Jacqueline SAIAS-MAGNAN, MD, Jessika MOREAU, MD, Julie BARBERET, MD, Julien BESSONAT, MD, Laetitia LADUREAU-FRITSCH, MD, Laure CHAPUT, PD, Laëtitia HESTERS, PharmD, Lise LACLAUTRE, Pharm D, Louis BUJAN, MD, Marion BENDAYAN, MD, Marius TELETIN, MD, PhD, Myriam DAUDIN, MD, Nathalie MOINARD, MD, Nathalie RIVES, MD, Nelly FRYDMAN, PharmD, PhD, Olivier BINOIS, MD, Patricia FAUQUE, MD, PhD, Pierre DI PIZIO, MD, Rachel LEVY, MD, Rahaf HAJ HAMID, MD, Sandrine GISCARD D'ESTAING, MD, PhD, Sara KOUIRI, MD, Solmaz SARANDI, MD, Solène VORILHON, MD, PhD, Sylvianne HENNEBICQU, MD, PhD, Thomas BOUEILH, MD, Virginie BARRAUD-LANGE, MD, PhD, Véronique DROUINEAUD, MD 2020-07-29
Impact Nerium Oleander on Symptoms and Mortality: A Feasibility Study Coronavirus disease 19 infection Nerium oleander proprietary extract alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) HealthQuilt Baylor College of Medicine, Texas A&M University System, The Hildebrand Fund at the Greater Houston Community Foundation, The Schull Institute, University of Maryland College Park, University of Texas Health Science Center Houston US 2020-05-20 2020-09-01 052020, NCT04486144 Phase 2 Clinical Recruiting 1 3 Months 100 Kim Dunn, MD, Ph.D. 2020-07-29
Online 1-day CBT-based Workshops for PPD Coronavirus disease 19 infection, Postnatal depression cognitive behavioural therapy based workshop alone, standard postnatal care alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) McMaster University Canada 2020-04-20 2020-12-31 NCT04485000, ONLINE1DAYCBT Phase Not Applicable Recruiting 1 8 Months 388 Ryan Van Lieshout, MD, PhD 2020-07-29
Thymalfasin (Thymosin Alpha 1) to Treat COVID-19 Infection (Ta1) Coronavirus disease 19 infection, Lymphocytopenia standard of care alone, thymalfasin alone Thymosin receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rhode Island Hospital US 2020-07-31 2021-04-30 NCT04487444, SCN-16130571-2 Phase 2 Clinical Not yet recruiting 1 9 Months 80 Eleftherios Mylonakis, MD PhD FIDSA, Fadi Shehadeh 2020-07-30
I-SPY_COVID: An Adaptive Platform Trial for Critically Ill Patients Coronavirus disease 19 infection, Respiratory distress syndrome ARDS supportive care alone, anticoagulation treatment alone, lung protective ventilation alone, Variable regimens including apremilast , cenicriviroc , icatibant , razuprotafib , remdesivir Bradykinin B2 receptor antagonist, CCR2 chemokine antagonist, CCR5 chemokine antagonist, COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, PDE 4 inhibitor, Protein tyrosine phosphatase beta inhibitor, RNA polymerase modulator, Tek tyrosine kinase receptor stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) QuantumLeap Healthcare Collaborative, US, University of California San Francisco Aerpio Pharmaceuticals Inc, Columbia University, Emory University, Montefiore Medical Center, Sanford Health, University of Alabama at Birmingham, University of California San Diego, University of Colorado, Denver, US, University of Minnesota, University of Pennsylvania, University of Southern California, Wake Forest University Health Sciences, US, Yale University US 2020-07-25 2022-11-01 I-SPY-COVID, I-SPY_COVID, NCT04488081 Phase 2 Clinical Recruiting 10 27 Months 1500 Carolyn Carolyn, MD, Karyn DiGiorgio, MS, Kathleen D Liu, MD, Laura Esserman, MD, Michelle Gong, MD, Paul Berger, MD, Paul Henderson, PhD 2020-08-06
LUS-COVID: Lung Ultrasound in COVID-19 Patients Coronavirus disease 19 infection invasive ventilation alone, lung ultrasound examination alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Academic Medical Center, University of Amsterdam Centre Hospitalier Universitaire Saint Pierre, Ospedale generale regionale F. Miulli, Acquaviva delle Fonti, Universita di Bari, Universita' Degli Studi Di Foggia Netherlands 2020-06-01 2020-10-31 LUS-COVID, LUS-COVID, NCT04487769 Phase Not Applicable Recruiting 1 5 Months 30 Charalampos Pierrakos, MD, Lieuwe D Bos, MD PhD, Luigi Pisani, MD, Marcus J Schultz, MD, Marcus J Schultz, MD PhD 2020-07-30
COVID-19 Phobia in Patients With Bronchiectasis During Covid-19 Pandemic Anxiety disorder, Bronchiectasis, Coronavirus disease 19 infection, Phobia Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Hacettepe University Turkey 2020-07-23 2020-12-01 GO 20/602, NCT04487873 Phase Not Applicable Not yet recruiting 1 4 Months 28 Aslıhan Cakmak, MSc, Deniz İnal-İnce, Professor, Ebru Calik-Kütükcü, PhD, Melda Saglam, PhD, Merve Firat, MSc, Naciye Vardar-Yagli, PhD 2020-07-30
COVIE-19/20: Screening for Postpartum Depression and Associated Risk Factors Among Women Who Deliver in Four Hospital in France During the COVID-19 Epidemic Coronavirus disease 19 infection, Postnatal depression Edinburgh Postnatal Depression Scale alone, Mother-to-Infant Bonding Scale alone, State-Trait Anxiety Inventory alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire D Amiens Centre Hospitalier Compiègne, Centre hospitalier de Beauvais, Hospital Center De Saint-Quentin France 2020-07-21 2021-08-31 COVIE-19/20, NCT04487171, PI2020_843_0049 Phase Not Applicable Recruiting 1 13 Months 248 Arthur FOULON, MD, Arthur Foulon, MD, MD, Xavier BENAROUS, MD 2020-07-31
ISAM-COVID: Survey on COVID-19 Airway Management Coronavirus disease 19 infection, Respiratory failure Healthy volunteers accepted Sociedad Española de Anestesiología, Reanimación y Terapéutica del Dolor Spain 2020-04-22 2020-09-30 ISAM-COVID, ISAM-COVID, NCT04487977 Phase Not Applicable Recruiting 1 5 Months 5000 Dr. Manuel Granell Gil, Manuel Granell Gil, Manuel Granell Gil, Dr, Manuel Granell Gil, PhD 2020-08-04
Addressing COVID-19 Mental Health Problems Among US Veterans Acute stress disorder, Coronavirus disease 19 infection short video intervention alone, vignette intervention alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Research Foundation for Mental Hygiene Inc US 2020-07-06 2020-09-10 8006, NCT04484207 Phase Not Applicable Recruiting 1 2 Months 200 Doron Amsalem, MD, Yuval Neria Neria, PhD, Yuval Neria, PhD 2020-07-29
Study of acute stroke with COVID-19 Coronavirus disease 19 infection, Stroke Japan Stroke Society, Nippon Medical School Hospital Japan 2020-07-08 UMIN000041226 Phase Not Applicable Recruiting 1 100 Kazumi Kimura, Yasuhiro Nishiyama 2020-07-31
Nebulized PL for Post-COVID-19 Syndrome Coronavirus disease 19 infection, Dyspnea, Respiratory disease, Respiratory distress syndrome, Viral pneumonia nebulized platelet lysate alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Regenexx LLC US 2020-08-03 2021-12-30 NCT04487691, RGX2020-RCT01 Phase 1 Clinical Not yet recruiting 1 16 Months 40 Christopher Centeno, MD, Ehren Dodson, PhD, Neven Steinmetz, PhD 2020-08-06
A trial to evaluate sbk-001 for the treatment of SARS-CoV-2 infection (COVID-19) Coronavirus disease 19 infection sbk-001 alone Angiotensin converting enzyme 2 inhibitor Chengdu Shibeikang Biological Medicine Technology Co Ltd Phase Not Applicable Planned 0 2020-07-28
Oral Manifestations of Coronavirus Disease 2019(COVID-19) :a Multicenter Study Coronavirus disease 19 infection Young Adults (18-44 yrs) Cairo University Egypt 2020-09-15 2020-12-15 8791, NCT04487665 Phase Not Applicable Not yet recruiting 1 3 Months 50 Dina mounir elkady 2020-07-29
Immune responses in the convalescence stage of COVID-19 patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Yokohama City University Japan 2020-09-01 UMIN000041227 Phase Not Applicable Not yet recruiting 1 140 Atsushi Goto, Takeharu Yamanaka 2020-07-30
J-DESIRE: Japan COVID-19 Survey and Questionnaire in inflammatory bowel disease Anxiety disorder, Coronavirus disease 19 infection, Psychiatric disorder questionnaire survey alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Japanese Ancestry Sapporo Medical University School of Medicine Japanese Ministry of Health, Labor and Welfare Japan 2020-07-28 J-DESIRE, UMIN000041191 Phase Not Applicable Not yet recruiting 2 2500 Hiroshi Nakase, Kohei Wagatsuma 2020-07-30
CoV-Hep: Regional Anticoagulation Modalities in Continuous Venous Venous Hemodialysis in Patients With COVID-19 Coronavirus disease 19 infection, Renal injury continued venovenous hemodialysis alone, polysulfone dialyzer alone, sodium citrate plus unfractionated heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo Brazil 2020-06-29 2021-07-31 33351120.0.0000.0068, 4.081.688, CoV-Hep, NCT04487990, RBR-45kf9p, U1111-1252-0194 Phase 2 Clinical Recruiting 1 13 Months 90 Camila Rodrigues, MD, PhD, Paulo Lins, MD 2020-07-30
A clinical study of monoclonal antibody therapeutic (subcutaneous, COVID-19), Centivax for COVID-19 patients Coronavirus disease 19 infection monoclonal antibody therapeutic (subcutaneous, COVID-19), Centivax alone Centivax Inc Phase Not Applicable Planned 0 2020-07-28
A correlation study to assess the serological ELISA and virus neutralization assays in the diagnosis of covid-19 Coronavirus disease 19 infection ELISA antibody test alone, virus microneutralization assay alone GenScript Biotech Corp Phase Not Applicable Status not specified 0 228 2020-08-06
A study to assess cPass test in detection of COVID-19 Coronavirus disease 19 infection cPass alone GenScript Corp Singapore, China Phase Not Applicable Status not specified 2 625 2020-07-29
Evaluation of the effect of Afsantin on COVID-19 Coronavirus disease 19 infection Afsantin alone, standard treatment alone Kurdistan University of Medical Sciences Iran 2020-07-10 IR.MUK.REC.1399.048, IRCT20190415043279N6 Phase 3 Clinical Recruiting 1 80 Dr. Afshin Maleki, Noshad Mohammadi, Sabah Hasani 2020-07-29
Evaluation of Convalescent Plasma Therapy for COVID-19 Patients Coronavirus disease 19 infection Convalescent plasma therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Shahid Sadoughi University of Medical Sciences and Health Services Iran 2020-09-22 IR.SSU.REC.1399.001, IRCT20200503047281N1 Phase 0 Clinical Not yet recruiting 1 40 Dr. Farzaneh Fesahat, Dr. Hossein Hadinedoushan, Dr. Masoud Mirzaei, Dr.Hossein Hadinedoushan 2020-07-29
COVID19 - Curosurf_ARDS_COV19: Poractant Alfa - Curosurf and SARS-COV-19 ARDS (Covid-19) Coronavirus disease 19 infection, Respiratory distress syndrome Curosurf alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chiesi Farmaceutici SpA UK 2020-07-08 2020-11-30 2020-002632-75, CLI-050000-04, COVID19 - Curosurf_ARDS_COV19, NCT04502433 Phase 2 Clinical Recruiting 1 4 Months 85 Chiesi Clinical trial Info, Clark Howard, Prof. /MD 2020-08-07
Needs, Perceptions and Acute Stress of Healtcare Workers Caring for COVID-19 Patients in South America Acute stress disorder, Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidad Miguel Hernandez de Elche Pontificia Universidad Catolica De Chile, Universidad Catolica Santiago de Guayaquil, Universidad de Santander, University of Sao Paulo Chile, Ecuador, Spain, Colombia 2020-04-01 2020-08-30 08/04/2020, NCT04486404 Phase Not Applicable Recruiting 4 4 Months 2500 Jose J Mira, PhD 2020-07-28
A prospective, open study on off-label use of tocilizumab for the treatment of SARS-CoV-2 pneumonia in Milan, Italy Coronavirus disease 19 infection, Pneumonia tocilizumab alone ASST Fatebenefratelli Sacco Italy Phase 2 Clinical Status not specified 1 51 2020-07-28
A phase II trial to evaluate AP-003 for the treatment of patients with COVID-19 Coronavirus disease 19 infection interferon alpha-2b (COVID-19, inhaled), Altum Pharmaceuticals alone Interferon alpha ligand modulator BetterLife Pharma Inc Altum Pharmaceuticals Inc Phase 2 Clinical Planned 0 150 2020-07-27
Effect of lavender syrup on COVID-19 Coronavirus disease 19 infection, Cough lavender syrup alone, supportive treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Gorgan University of Medical Sciences Iran 2020-05-16 IR.GOUMS.REC.1399.025, IRCT20110907007511N4 Phase 3 Clinical Recruiting 1 30 Dr. Marzieh Qaraati, Marzieh Qaraati 2020-07-28
Clinical Outcome of Anti-IL6 versus Anti-IL6 Corticosteroid Combination in Patients With SARS-CoV-2 Cytokine Release Syndrome Coronavirus disease 19 infection, Systemic inflammatory response syndrome, Viral pneumonia siltuximab alone, tocilizumab alone Heat shock protein inhibitor, IL-6 receptor antagonist Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) King Faisal Specialized Hospital & Research Center Society of Critical Care Medicine Saudi Arabia 2020-07-22 2021-07-22 NCT04486521, RAC # 2201053 Phase Not Applicable Recruiting 1 12 Months 11000 Abeer AlFirm, Associate RC Data Manager, Abeer Omar, Abid Butt, MD, Eiad Kseibi, MD, Maal Abualkhair, MD, Marwa Amer, PharmD, BCPS,BCCCP, Marwa Amer, PharmD,BCPS, BCCCP, Mohammed Abujazar, MD, Mohammed Bawazeer, MD, FRCSC, FACS, Mohammed Bawazeer, MD,FRCSC,FACS, Muath Rabee, MD, Razan Alghunaim, PharmD, Syed Moazzum Khurshid, MD, Talal Dahhan, MD 2020-07-29
DISCO: Disulfiram for COVID-19 (DISCO) Trial Coronavirus disease 19 infection disulfiram (Antabuse) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of California San Francisco US 2020-09-01 2021-09-01 DISCO, DSF151837, NCT04485130 Phase 2 Clinical Not yet recruiting 1 12 Months 60 Priscilla Hsue, MD, Rada Savic, PhD, Steven G Deeks, MD, Sulggi A Lee, MD PhD 2020-07-28
BIOCOVID: Place of Circulating Biomarkers and Respiratory Eicosanoids in the Prognosis of Severe Forms of COVID-19 Pneumonia Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory tract infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Groupe Hospitalier Paris Saint-Joseph Centre Hospitalier Victor Dupouy, Versailles University Hospital France 2020-04-14 2020-10-31 BIOCOVID, BIOCOVID, NCT04485364 Phase Not Applicable No longer recruiting 1 6 Months 100 2020-07-29
A phase I trial to evaluate CoronaVac for the prevention of COVID-19 Coronavirus disease 19 infection CoronaVac alone Dynavax Technologies Corp Medigen Vaccine Biologics Corp 2020-09-30 Phase 1 Clinical Planned 0 2020-07-27
The evaluation of isotretinoin effects on treatment of COVID-19 infections Coronavirus disease 19 infection isotretinoin alone, standard of care alone Retinoic acid receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kermanshah University of Medical Sciences Iran 2020-08-22 IR.KUMS.REC.1399.288, IRCT20190624043993N3 Phase 3 Clinical Not yet recruiting 1 50 ALI akrami, Dr. Farid Najafi, Foroud Shahbazi, Maria Shirvani 2020-07-28
Effect of omega-3 on diabetic patients with covid-19 Coronavirus disease 19 infection Variable regimens including docosahexaenoic acid , eicosapentaenoic acid , hydroxychloroquine Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tehran University of Medical Sciences Iran 2020-02-20 IR.TUMS.VCR.REC.1399.440, IRCT20200511047399N1 Phase 3 Clinical No longer recruiting 1 30 Hamed Abdollahi, Mina Abdolahi 2020-07-28
Trial to Evaluate Efficacy and Safety of Nitazoxanide in the Treatment of Mild or Moderate COVID-19 Coronavirus disease 19 infection, Respiratory disease nitazoxanide (controlled-release, viral infections), Romark plus vitamin super B-complex Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Romark Laboratories LC 2020-07-30 2020-10-30 NCT04486313, RM08-3008 Phase 3 Clinical Not yet recruiting 0 3 Months 800 Stefan Comhaire 2020-07-28
A Clinical Study to Assess the Physiologic Effects of KB-109 in Patients With COVID-19 on Gut Microbiota Structure and Function Coronavirus disease 19 infection KB-109 alone, Self Supportive Care (SSC) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kaleido Biosciences Inc US 2020-07-31 2021-03-31 K032-120, NCT04486482 Phase 2 Clinical Recruiting 1 8 Months 50 Courtney Balliro, RN,BS,CDE, Mark Wingertzahn, PhD 2020-07-28
Chest Radiography in COVID‒19 Patients Coronavirus disease 19 infection, Pulmonary edema invasive ventilation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Academic Medical Center, University of Amsterdam Chonburi Hospital, Mahidol University, Universita di Bari, Universitair Ziekenhuis Brussel Netherlands 2020-08-01 2021-03-01 NCT04485338, RALE-COVID Phase Not Applicable Not yet recruiting 1 7 Months 200 Christel M. A. Valk, MSc, Claudio Zimatore, MSc, Marcus J. Schultz, Prof. 2020-07-30
A clinical trial to evaluate NurOwn for the treatment of patients with COVID-19 ARDS Coronavirus disease 19 infection, Respiratory distress syndrome NurOwn alone Brain derived neurotrophic factor ligand, Glial cell neurotrophic factor ligand BrainStorm Cell Therapeutics Inc Phase Not Applicable Planned 0 2020-07-27
CONFI-DIAB: Assessing the Impact of the COVID-19 Lockdown on Metabolic Control and Access to Health Care in Patients With Diabetes Coronavirus disease 19 infection, Diabetes mellitus Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Hospital, Nancy, France France 2020-07-31 2020-09-30 2020PI137, CONFI-DIAB, NCT04485351 Phase Not Applicable Recruiting 1 2 Months 700 Lisa Ludwig, Dr 2020-07-28
ACCESS: Safety Net Support Use in California Coronavirus disease 19 infection earned income tax credit-safety net support program alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), African Ancestry University of California at Berkeley University of California San Francisco US 2020-07-21 2022-06-30 048228-001, ACCESS, NCT04485377 Phase Not Applicable Not yet recruiting 2 23 Months 530 2020-07-28
INSPIRATION: Intermediate-dose versus Standard Prophylactic Anticoagulation and Statin versus Placebo in ICU Patients With COVID-19 Coronavirus disease 19 infection atorvastatin alone, enoxaparin sodium plus unfractionated heparin HMG CoA reductase inhibitor, Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rajaie Cardiovascular Medical and Research Center Brigham & Women's Hospital, Firuzgar hospital, Imam General Hospital, Masih Daneshvari Hospital, Modarres Hospital, Rasoul Akram Hospital, Sina Hospital, Tabriz University of Medical Sciences, Tehran Heart Center US, Iran 2020-07-30 2020-12-06 99060, INSPIRATION, NCT04486508 Phase 3 Clinical Recruiting 3 4 Months 600 Babak Sharif Kashani, Behnood Bikdeli, MD, MS, Parham Sadeghipour, MD, Sara Tayyebi, MS 2020-08-05
Feasibility of a Telematics Pre-operative Assessment in a Bariatric Surgery During Covid-19 Coronavirus disease 19 infection, Obesity low calorie diet alone, telemedicine alone, very low calorie diet alone, very low calorie ketogenic diet alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Universita degli Studi di Roma La Sapienza Italy 2020-06-01 2020-07-31 66.20, NCT04486417 Phase Not Applicable Recruiting 1 2 Months 20 Gianfranco Silecchia, Gianfranco Silecchia, FULL PROFESSOR, Laura Pierro, PhD 2020-07-29
Efficacy Assessment of Methylprednisolone and Heparin in Patients With COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia enoxaparin sodium alone, methylprednisolone alone, standard treatment alone, unfractionated heparin alone, Variable regimens including enoxaparin sodium , methylprednisolone , unfractionated heparin Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto D'Or de Pesquisa Brazil 2020-07-20 2020-12-31 31180820600005249, NCT04485429 Phase 3 Clinical Recruiting 1 5 Months 268 Abel Costa Neto, MD, Eduardo M Rego, MD, PhD 2020-07-28
Evaluation of Non Invasive Ventilator Acidosis, Coronavirus disease 19 infection, Viral pneumonia BiPAP Auto Biflex Philips Respironics IN761S alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Council of Scientific and Industrial Research (India) India 2020-07-22 CTRI/2020/07/026607 Phase Not Applicable Not yet recruiting 1 10 Dr Sathyanarayana Mysore 2020-07-28
Efficacy of the early use of corticotherapy in CoV-2 infection to prevent the progression of acute respiratory distress syndrome (ARDS) Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia methylprednisolone (Pfizer) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) VHIR Vall d'Hebron Institut de Recerca Spain 2020-06-03 2020-002186-34, MP_COVID19 Phase 4 Clinical Recruiting 1 100 Ferran Martínez Valle 2020-07-28
A phase III clinical trial to study the safety and efficacy of of ChAdOx1 nCoV-19 in healthy volunteers Coronavirus disease 19 infection AZD-1222 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) University of Oxford UK 2020-05-31 Phase 3 Clinical Status not specified 1 2020-07-27
Clinical trial to evaluate the efficacy and safety of gammaglobulins in COVID-19 treatment Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure, Shock, Viral pneumonia Flebogamma 10% DIF alone, Flebogamma DIF 5% alone Beta amyloid modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) San Antonio Technologies - San Antonio Catholic University of Murcia Spain 2020-06-10 2020-001890-56, COVID-Γ Phase 4 Clinical Recruiting 1 100 Bioithas 2020-07-28
A clinical study of Avigan in Kuwait for COVID-19 treatment Coronavirus disease 19 infection favipiravir alone RNA polymerase inhibitor FUJIFILM Holdings Corp Dr Reddy's Laboratories Ltd Kuwait Phase Not Applicable Planned 1 1000 2020-07-27
Prognostic Factors in Patients Admitted to an Urban Teaching Hospital With COVID-19 Infection Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Glasgow Royal Infirmary University NHS Trust UK 2020-04-01 2021-06-01 IRAS 282807, NCT04484545 Phase Not Applicable No longer recruiting 1 14 Months 250 Donogh Maguire, PhD 2020-07-27
AbOcCov: Search for antiviral antibodies in COVID-19 patients' eye secretions Coronavirus disease 19 infection University of Ferrara Italy 2020-05-20 2020-12-31 544-2020, AbOcCov, ISRCTN17301812 Phase Not Applicable Recruiting 1 7 Months 60 Prof Caselli 2020-07-28
ESCORPIO: Controlled trial on the usefulness of pioglitazone treatment in patients with type 2 diabetes mellitus and COVID-19 Coronavirus disease 19 infection, Non-insulin dependent diabetes pioglitazone alone, standard treatment alone Insulin sensitizer, PPAR gamma agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundación Investigación Biomédica Hospital Ramón y Cajal Spain 2020-06-16 2020-001929-31, ESCORPIO, ESCORPIO Phase 4 Clinical Recruiting 1 76 Anabel Sánchez 2020-07-27
Corticosteroid Nasal Spray in COVID-19 Anosmia Coronavirus disease 19 infection, Dysomia mometasone furoate alone, olfactory training alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Benha University Egypt 2020-08-01 2020-09-01 NCT04484493, RC 4-7-2020 Phase 3 Clinical Not yet recruiting 1 1 Month 50 Abdelhakim F Ghallab, MD, Abdelrahman A Abdelalim, MD, Mona A Elawady, MD, Rasha A Elsayed, MD 2020-07-28
A clinical trial of vaccine (Dynavax adjuvant CpG1018, Bordetella pertussis infection), Serum Institute of India for the prevention of covid-19 Coronavirus disease 19 infection vaccine (Dynavax adjuvant CpG1018, Bordetella pertussis infection), Serum Institute of India alone TLR-9 agonist Dynavax Technologies Corp, Mount Sinai Medical Center, National Institute of Allergy and Infectious Diseases National Institutes of Health Phase 1 Clinical Planned 0 2020-07-24
Predictors of COVID-19 Infection and Disease Progression (Portsaiduni) Coronavirus disease 19 infection CT chest imaging alone, Rt-PCR testing alone, ancillary diagnostic test alone, clinical picture analysis alone Healthy volunteers accepted Port Said University, Egypt Egypt 2020-03-15 2020-09-15 NCT04484597, PROF. REFAT SADEQ Phase Not Applicable Recruiting 1 6 Months 100 Refat A. Sadeq, Ph D 2020-07-28
TOCICOVID: Phase III, Randomized, Unicentric, Open, Controlled Clinical Trial To Demonstrate The Effectiveness Of Tocilizumab Against Systemic Corticotherapy In Patients Entered By COVID-19 With Bilateral Pneumonia And Bad Evolution Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia tocilizumab (intravenous), Roche/Chugai alone IL-6 receptor antagonist, IL-6 receptor modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto Biodonostia Spain 2020-06-25 2020-001707-16, TOCICOVID, TOCICOVID Phase 3 Clinical Recruiting 1 60 IIS BIODONOSTIA 2020-07-27
A phase III clinical trial of SARS-CoV-2 vaccine for the treatment of COVID-19 Coronavirus disease 19 infection SARS-CoV-2 vaccine (corona virus disease 19 infection), Research Institute of Influenza alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Research Institute of Influenza Phase 3 Clinical Recruiting 0 100 2020-07-24
HUB-MdI-ICAT-COVID-201: Investigating the Efficacy and Safety Icatibant For The Treatment of Patients with SARS-CoV-2 (COVID-19) Infection Coronavirus disease 19 infection, Viral pneumonia icatibant alone Bradykinin B2 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) L'Hospitalet de Llobregat pending23 Spain 2020-07-09 2020-002166-13, HUB-MdI-ICAT-COVID-201, HUB-MdI-ICAT-COVID-201 Phase 2 Clinical Recruiting 1 120 Dr. Ramón Lleonart Bellfill 2020-07-27
SulES-COVID: Suloexide in the Treatment of Early Stages of COVID-19 Chronic obstructive pulmonary disease, Coronavirus disease 19 infection, Myocardial disease, Renal injury, Respiratory failure, Thrombosis sulodexide alone Heparin agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) CLINEDEM, Mexico Alfasigma SpA Mexico 2020-06-05 2020-08-10 CLIDM/VAS/2020-05-01, NCT04483830, SulES-COVID Phase 2/Phase 3 Clinical Recruiting 1 2 Months 250 Alejandro j Gonzalez-Ochoa, md, alejandro j Gonzalez-Ochoa, MD, alejandro j gonzalez ochoa, md 2020-07-27
amb-COVID: The state of health of ambulatory patients after COVID-19 disease Coronavirus disease 19 infection Jena University Hospital Germany 2020-08-01 2020-1834-Bef, DRKS00022498, amb-COVID Phase Not Applicable Not yet recruiting 1 1000 Ms. Dana Loudovici-Krug, Ms. Dr. med Christina Lemhöfer 2020-07-27
A study to assess clinical validation of Adeptrix COVID-19 diagnostic test Coronavirus disease 19 infection Adeptrix COVID-19 diagnostic test alone Avacta Ltd Phase Not Applicable Not yet recruiting 0 2020-07-28
CORONATION: Coronavirus (COVID-19) multinational, observational registry Coronavirus disease 19 infection Cambridge University Hospitals NHS Foundation Trust, University of Cambridge NIHR Cambridge Biomedical Research Centre Italy, Albania, Switzerland, Romania, Tunisia, Netherlands, Turkey, Sweden, Czech Republic, Finland, Bosnia and Herzegovina, Belgium, Macedonia, The Former Yugoslav Republic of, Norway, Belarus, Latvia, Slovakia, Poland, Serbia, Russian Federation, UK, Estonia, France, Georgia, Portugal, Austria, Greece, Denmark, Spain, Ukraine, Croatia, Cyprus, Lithuania, Bulgaria, Iceland, Israel 2020-04-06 2025-04-24 CCTU0304, CORONATION, IRAS 282239, ISRCTN17717312 Phase Not Applicable Not yet recruiting 38 60 Months Dr Kerrie Brusby, Dr Thomas F Hiemsra 2020-07-27
A study to assess safety of SARS-CoV-2 Spike Protein for the potential treatment of Covid-19 Coronavirus disease 19 infection TerraCoV2 vaccine (COVID-19), Noachis Terra alone COVID19 Spike glycoprotein modulator Oragenics Inc 2021-01-01 Phase 1 Clinical Planned 0 2020-07-24
SPI-1005 Treatment in Moderate COVID-19 Patients Coronavirus disease 19 infection ebselen (oral, hearing loss/bipolar disorder/ ototoxicity/Meniere disease/SARS-CoV-2 infection (COVID-19)), Sound Therapeutics alone Glutathione peroxidase stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sound Pharmaceuticals Inc US 2020-08-31 2020-12-31 NCT04484025, SPI-1005-291 Phase 2 Clinical Not yet recruiting 1 4 Months 60 Haifan Lin, PhD, Jonathan Kil, MD, Miriam Treggiari, MD 2020-08-03
The Effect of Omega-3 on Selected Cytokines Involved in Cytokine Storm Coronavirus disease 19 infection omega3 fatty acid alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Applied Science Private University Jordan 2020-08-05 2020-12-05 2020-PHA-18, NCT04483271 Phase Not Applicable Not yet recruiting 1 4 Months 100 Mahmoud S Abu-Samak, PhD, Mahmoud Suleiman Abu-Samak, Rafeef A Al-Khaled, MSC 2020-07-27
Breathing Techniques and Meditation for Health Care Workers During COVID-19 Pandemic Acute stress disorder, Coronavirus disease 19 infection, Lung disease Meditation Therapy alone, Quality-of-Life Assessment alone, Questionnaire alone, Yoga alone, breathing techniques alone Healthy volunteers accepted, Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) MD Anderson Cancer Center National Cancer Institute US 2020-06-17 2021-07-01 2020-0483, NCI-2020-04931, NCT04482647, P30CA016672 Phase 1 Clinical Recruiting 1 12 Months 50 Santhosshi Narayanan 2020-07-28
SEROBL-COVID19: COVID-19 in Baselland: Investigation and Validation of Serological Diagnostic Assays and Epidemiological Study of Sars-CoV-2 Specific Antibody Responses Coronavirus disease 19 infection ELISA tests alone, PCR testing alone, biological sampling alone, point of care (POC) assay alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Basel Department of Health, Economics and Health Directorate Canton Basel-Land, ETH Zurich Switzerland 2020-04-10 2022-05-30 BASEC PROJECT-ID 2020-00816, NCT04483908, SEROBL-COVID19 Phase Not Applicable Recruiting 1 25 Months 550 Carlos Quinto, Dr. med., Miodrag Savic, Dr. med. 2020-07-27
CORIVER: Ivermectin as antiviral treatment for patients infected by SARS-COV2 (COVID19) Coronavirus disease 19 infection, Viral pneumonia ivermectin alone Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hospital Universitario Virgen de las Nieves Spain 2020-06-02 2020-001971-33, CORIVER, CORIVER Phase 3 Clinical Recruiting 1 45 Sergio Sequera 2020-07-29
MADRID-COVID: MADRID-COVID Coronavirus disease 19 infection, Respiratory distress syndrome metoprolol tartrate (Beloken) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto de Investigación Sanitaria de la Fundacion Jimenez Diaz Spain 2020-06-15 2020-002310-41, MADRID-COVID, MADRID-COVID Phase 2 Clinical Recruiting 1 20 NOEMI ESCALERA 2020-07-31
Tele-rehabilitation Versus Home Exercise Program in COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome Home exercise alone, Remote controlled exercise alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Koc University Turkey 2020-08-31 2022-08-31 2020.219.IRB1.069, NCT04482634 Phase Not Applicable Not yet recruiting 1 24 Months 122 Baris Ata, Prof, Ihsan Solaroglu, Prof, Mahir Topaloglu, MD, Ozden Ozyemisci Taskiran, Prof, Zeynep Turan, MD 2020-07-28
Effect of two covers to prevent injuries caused to professionals working in the health area due to the use of personal protective equipment Coronavirus disease 19 infection, Decubitus ulcer cover based on polyurethane foam alone, cover with extra-fine hydrocolloid coating alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidade Estadual de Campina Fundo de apoio ao ensino, à pesquisa e extensão - Faepex Brazil 31786020.0.0000.5404, RBR-7drpyr Phase Not Applicable No longer recruiting 1 88 Renata Cristina Gasparino 2020-07-28
Study to Evaluate Pharmacokinetic (PK), Safety and Tolerability of Cabotegravir 400 mg/ml Formulation in Healthy Adult Participants Coronavirus disease 19 infection, HIV infection cabotegravir (long-acting injectable, HIV prevention), ViiV alone, cabotegravir (oral), ViiV Healthcare alone HIV integrase inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) ViiV Healthcare Ltd 2020-08-07 2022-04-27 212482, NCT04484337 Phase 1 Clinical Not yet recruiting 0 20 Months 124 EU GSK Clinical Trials Call Center, GSK Clinical Trials, US GSK Clinical Trials Call Center 2020-07-27
Use of Technology and Telemedicine to Improve Quality of Care in COVID-19 Patients Coronavirus disease 19 infection Doctorgram Mobile Application alone, Doctorgram Patient Kit alone, Remote Pulse Oximeter alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Stanford University US 2020-08-31 2021-02-28 56472, NCT04480411 Phase Not Applicable Not yet recruiting 1 6 Months 165 Julieta M Gabiola, MD, Lisa Shieh, MD, Nicholas Scoulios, MD, Ritu Parikh, MD 2020-07-28
Impact of Covid-19 on Frequent Social Interaction Through Communication Technologies in the Cognitive Status of Socially-isolated Older Adults Amnesia, Cognitive disorder, Coronavirus disease 19 infection Technology based social interactions alone Healthy volunteers accepted Boston University US 2020-08-31 2021-05-31 H-26786, NCT04480112 Phase Not Applicable Not yet recruiting 1 9 Months 150 Andrew E Budson, MD, Andrew E Busdon, MD, Rocco Pallumbo, PhD 2020-07-29
SPI-1005 Treatment in Severe COVID-19 Patients Coronavirus disease 19 infection ebselen (oral, hearing loss/bipolar disorder/ ototoxicity/Meniere disease/SARS-CoV-2 infection (COVID-19)), Sound Therapeutics alone Glutathione peroxidase stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sound Pharmaceuticals Inc US 2020-08-31 2020-12-31 NCT04483973, SPI-1005-292 Phase 2 Clinical Not yet recruiting 1 4 Months 60 Haifan Lin, PhD, Jonathan Kil, MD, Miriam Treggiari, MD 2020-08-03
PROTECT: Preventing COVID-19 With High-dose Vitamin D Supplements Coronavirus disease 19 infection vitamin D alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) CHU de Quebec-Universite Laval Canadian Institutes of Health Research, Laboratoire Riva Inc Canada 2020-09-01 2021-06-30 MP-21-2021-3044, NCT04483635, PROTECT Phase 3 Clinical Not yet recruiting 2 10 Months 2414 Annie Chamberland, Annie Theoret, Annie Théoret, Cecile Tremblay, MD, Francine M Ducharme, MD, Francine M Ducharme, MD, M.Sc. 2020-07-27
The Change of Critical Patient Managements and Subsequent Influences Under Epidemic of Coronavirus Disease 19 (COVID-19) Acute stress disorder, Coronavirus disease 19 infection, Surgical procedure Negative Pressure Isolation Room alone, Resuscitation Area alone, Tracheal intubation alone, cardiopulmonary resuscitation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Taiwan University Hospital Taiwan 2020-08-01 2022-07-31 202005094RIND, NCT04479332 Phase Not Applicable Not yet recruiting 1 24 Months 334 Min-Shan Tsai, MD 2020-07-28
COVID-19: Immunoglobulin G Antibody Immune Response Profile Following Infection With SARS-CoV-2 in COVID-19 Egyptian Patients Coronavirus disease 19 infection, Immune disorder RT-PCR assay alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sohag University Egypt 2020-06-12 2021-02-15 COVID-19, IBR#S20-133, NCT04483622 Phase Not Applicable Recruiting 1 8 Months 30 Asmaa Mohamed Goda, Asmaa m Goda, MD, asmaa m goda, MD 2020-07-27
Safety, Tolerability and Pharmacokinetics of SCTA-01, an Anti-SARS-CoV-2 Monoclonal Antibody, in Healthy Chinese Subjects Coronavirus disease 19 infection SCTA-01 alone COVID19 Spike glycoprotein inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry Sinocelltech Ltd China 2020-07-24 2021-01-15 NCT04483375, SCTA01-X101 Phase 1 Clinical Recruiting 2 5 Months 33 Ji Qi, PhD, Qing Liu, MSc, Wang Xinghe, PhD, Xinghe Wang, MD,PhD 2020-08-06
PRE-COVID: Pilot trial on early treatment with hydroxychloroquine in patients with COVID-19 who do not have hospital admission at diagnosis Coronavirus disease 19 infection, Viral pneumonia hydroxychloroquine alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidade de Santiago de Compostela Spain 2020-06-15 2020-002449-41, PRE-COVID, PRE-COVID Phase 3 Clinical Recruiting 1 340 ANTONIO ANTELA LOPEZ 2020-07-27
SilCOVID19: Randomized clinical trial to test if silibinin administration can prevent the respiratory failure secondary to the COVID-19 lung infection in oncological patients Coronavirus disease 19 infection, Lung infection, Respiratory failure Legalon alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto Catalan de Oncologia Girona Biomedical Research Institute Spain 2020-06-10 2020-001794-77, SilCOVID19, SilCOVID19 Phase 2 Clinical Recruiting 1 92 Clinical Research Unit 2020-07-28
SchoolCoviDD19: Prospective SARS-CoV-2 seroprevalence study of school children after the lockdown March 2020 (COVID-19) Coronavirus disease 19 infection blood sampling alone, manuscript alone, questionnaire alone University Hospital Carl Gustav Carus Germany 2020-05-18 BO-EK-156042020, DRKS00022455, SchoolCoviDD19 Phase Not Applicable No longer recruiting 1 600 Jakob Armann 2020-07-27
Epidemiological Characteristics of an Outbreak of 2019 Novel Coronavirus Diseases (COVID-19) in the Petaling District: A Descriptive Study Coronavirus disease 19 infection PEJABAT KESIHATAN BAHAGIAN KUCHING Malaysia 2020-08-01 NMRR-20-1540-55803 Phase Not Applicable Not yet recruiting 1 rama krishna a/l supramanian 2020-07-29
Perceptions about Ethics of Public Health Behavioral Interventions during the Covid 19 Outbreak Coronavirus disease 19 infection behaviorial changes alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institutes of Health (NIH), Ministry of Health Malaysia Malaysia 2020-08-01 NMRR-20-1542-55843 Phase Not Applicable Not yet recruiting 8 Asyraf Syahmi Bin Mohd Noor 2020-08-06
Comparison of PCR versus antigen from various sample types as diagnostic test in COVID-19 infection Coronavirus disease 19 infection Antigen detection alone, PCR assessment alone Hospital Sungai Buloh Malaysia 2020-08-01 55639, NMRR-20-1569-55639 Phase Not Applicable Not yet recruiting 1 31 Syarifah Nurul Ain Bt Syed Badaruddin 2020-08-06
EXCEL: Exercise for Cancer to Enhance Living Well Cancer, Coronavirus disease 19 infection Group Exercise alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Calgary Alberta Health Services, Dalhousie University, Memorial University, The University Health Network, University of Alberta, University of British Columbia, University of Prince Edward Island Canada 2020-08-01 2027-12-31 EXCEL, HREBA.CC-20-0098, NCT04478851 Phase Not Applicable Not yet recruiting 3 89 Months 1500 Julianna Dreger, M.ClinExPhys, Margaret L McNeely, PhD, Melanie Keats, PhD, Nicole Culos-Reed, PhD 2020-07-28
Fourth Trimester - A Web-based Tool for Postpartum Care to Address the Needs of Underserved Women Anxiety disorder, Coronavirus disease 19 infection, Postnatal depression Fourth Trimester Mobile Tool alone Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) HealthCore Inc, New England Research Institutes National Institute on Minority Health and Health Disparities, Orange Square Design, Inc. US 2020-07-06 2020-09-22 NCT04475718, R43MD014923 Phase Not Applicable Recruiting 2 2 Months 85 Juli Leonard, Julia Coleman, Kristine Merz, Lisa Marceau, MPH 2020-07-29
Combined Simultaneous EGD-colonoscopy Trial (CoSi Endoscopy) Colonoscopy, Coronavirus disease 19 infection A Fuji Lasereo 7000 alone, Olympus Evis Exera II alone, Simultaneous EGD and colonoscopy alone, colonoscopy alone, esophagogastroduodenoscopy (EGD) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Emura center Latinoamerica Universidad de la Sabana Colombia 2020-06-13 2020-09-15 2020-ECL-6-1, NCT04473456 Phase Not Applicable Recruiting 1 3 Months 40 FABIAN EMURA, FABIAN EMURA, PhD, Luis Giraldo, PhD 2020-07-30
ZSAC: Zurich Coronavirus Cohort: an observational study to determine long-term clinical outcomes and immune responses after coronavirus infection (COVID-19), assess the influence of virus genetics, and examine the spread of the coronavirus in the population of the Canton of Zurich, Switzerland Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Zurich Switzerland 2020-05-01 2022-09-30 ISRCTN14990068, ZSAC Phase Not Applicable Not yet recruiting 1 29 Months 2200 Dr Dominik Menges, Dr Dominik Menges, MPH, Dr Tala Ballouz, Prof Alexandra Trkola, Prof Christian Münz, Prof Jan Fehr, Prof Milo A. Puhan, Prof Roger Kouyos 2020-07-27
Building Family Caregiver Skills Using a Simulation-Based Intervention for Care of Cancer Patients Anal tumor, Colorectal tumor, Coronavirus disease 19 infection, Esophagus tumor, Larynx tumor, Metastatic head and neck cancer, Mouth tumor, Nasopharyngeal carcinoma, Non-small-cell lung cancer one-on-one teaching sessions alone, telephone booster contact alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Case Comprehensive Cancer Center National Institutes of Health US 2019-12-01 2023-04-30 CASE4Y19, NCT04055948 Phase Not Applicable Recruiting 1 41 Months 180 Susan Mazanec, PhD, Susan Mazanec, v 2020-07-29
The effects of Favipiravir and Lopinavir/Ritonavir in treatment COVID-19 Coronavirus disease 19 infection Interferon beta-1a (CinnaGen, Iran) plus favipiravir(Zhejiang Hisun, China) Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bandare-abbas University of Medical Sciences Iran 2020-07-25 IR.HUMS.REC.1399.225, IRCT20200506047323N3 Phase 3 Clinical Recruiting 1 60 Mahdi Hasani Azad, Mohammad Fathalipour, Teamur Aghamolaei 2020-07-27
Pat-steps Coronavirus disease 19 infection, Psychiatric disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Selayang Hospital Malaysia 2020-08-03 2020-10-30 NMRR-20-1538-55653 Phase Not Applicable Not yet recruiting 1 2 Months 146 Dr Son Wei Da 2020-07-28
Inconsistent RdRp gene detection causing false negative COVID-19 PCR Coronavirus disease 19 infection Teluk Intan Hospital Malaysia 2020-07-20 2020-07-27 55881, NMRR-20-1533-55881 Phase Not Applicable No longer recruiting 1 Dr Yong Jo Yen 2020-07-27
Preoperative Immature Granulocyte Count and Percentage for Acute Appendicitis Appendicitis, Coronavirus disease 19 infection Appendectomy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kahramanmaras Sutcu Imam University Turkey 2018-06-01 2019-06-01 180, NCT04440150 Phase Not Applicable Completed 1 12 Months 70 Mehmet Buğra Bozan 2020-07-27
SKILLZ: Reaching 90 90 90 in Adolescents in Zambia: Using All Our SKILLZ Coronavirus disease 19 infection, HIV infection SKILLZ-Girl Enhanced football curriculum alone Healthy volunteers accepted, Female, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Alabama at Birmingham Centre for Infectious Disease Research in Zambia, Grassroot Soccer (GRS), University of California San Francisco, Washington University School of Medicine, US Zambia 2020-03-01 2023-06-30 IRB-300002251, NCT04429061, SKILLZ Phase Not Applicable Recruiting 1 40 Months 3200 Carolyn Bolton, Carolyn Bolton, MPH, MD, Carolyn Dr Bolton, MPH, MD, Nancy Dr Padian, MPH, MD 2020-07-29
COGMA: Computerized Cognitive Training in Middle-Aged Adults With Generalized Anxiety Disorder: A Pilot Study Coronavirus disease 19 infection, Generalized anxiety disorder computerized cognitive Training alone Healthy volunteers accepted, Middle-aged Adults (45-64 yrs) University of Missouri US 2020-06-08 2021-05-31 2021943, COGMA, NCT04421690 Phase Not Applicable Recruiting 1 11 Months 30 Ashley Curtis, PhD, Jacob Wilhelm 2020-07-27
@LIITCI: Low Intensity Internet Therapy for Chronic Illness Anxiety disorder, Coronavirus disease 19 infection, Depression Acceptance and Commitment Therapy alone, Compassion-Focused Therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Coimbra Portugal 2020-05-01 2021-08-31 @LIITCI, LIIT, NCT04408651 Phase Not Applicable No longer recruiting 1 16 Months 54 Inês A Trindade 2020-07-27
Telerehabilitation in Disabled People: Proposal for Practical Intervention With Virtual Reality Coronavirus disease 19 infection Application of tele-rehabilitation alone Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Sao Paulo Brazil 2020-05-15 2020-11-01 03851012.7.0000.5390, NCT04402034 Phase Not Applicable Recruiting 1 5 Months 40 Carlos BM Monteiro, Ph.D., Carlos BM Monteiro, PhD, Talita D Silva, PhD 2020-07-28
Intervention for Caregivers of Patients Undergoing HSCT or CAR T-cell Therapy Anxiety disorder, Coronavirus disease 19 infection Psychoeducation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Case Comprehensive Cancer Center US 2020-07-17 2021-02-28 CASE8Z20, NCT04390542 Phase Not Applicable Not yet recruiting 1 7 Months 40 Sara Douglas, PhD, RN 2020-07-27
Stress and Anxiety Levels of Mothers Lying in the Baby Newborn Intensive Care Unit Anxiety disorder, Coronavirus disease 19 infection survey work alone Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Eskisehir Osmangazi University Turkey 2020-07-25 2020-12-25 DSAYIK1, NCT04386798 Phase Not Applicable Not yet recruiting 1 5 Months 60 AYFER ACIKGOZ, assoc. dr., DILEK SAYIK, expert nurse, OZLEM MUMCU, OZLEM MUMCU, expert nurse 2020-07-27
PARK-NU: Positive Affect Regulation skills at Northwestern University Anxiety disorder, Coronavirus disease 19 infection, Depression Positive Emotion Skills Course alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Northwestern University US 2020-04-27 2021-02-28 NCT04367922, PARK-NU, STU00212262 Phase Not Applicable Recruiting 1 10 Months 1000 Amanda Summers, MA, Judith Moskowitz, PhD 2020-07-27
Yoga in NHS Health Care Workers With COVID-19 Related Stress Acute stress disorder, Coronavirus disease 19 infection, Generalized anxiety disorder Zoom platform alone, online group session alone, sudarshan kriya yoga session alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Doncaster and Bassetlaw Hospitals NHS Foundation Trust UK 2020-07-01 2021-02-01 DBH 1058/2020/HRAS, NCT04481516 Phase Not Applicable Recruiting 1 7 Months 30 Emma Adams, Rachel Codling, Venkat D Nagarajan 2020-07-27
Social Anxiety Telehealth Therapy Study Coronavirus disease 19 infection, Social phobia Coordinated Anxiety Learning and Management (CALM) program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Stanford University US 2020-09-01 2021-07-01 56697, NCT04450303 Phase Not Applicable Not yet recruiting 1 10 Months 25 Tali Ball, PhD 2020-07-30
Evaluation of the Physical Activity Level of the Elderly in Social Isolation Coronavirus disease 19 infection Home exercise program alone Healthy volunteers accepted, Aged Adults (65-79 yrs), Elderly Adults (80 and over) Istinye Universitesi 2020-08-01 2020-11-20 008, NCT04480606 Phase Not Applicable Not yet recruiting 0 3 Months 88 2020-07-28
RAPA-CARDS: Effects of mTOR Inhibition With Sirolimus (RAPA) in Patients With COVID-19 to Moderate the Progression of ARDS Acute lung injury, Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia sirolimus alone mTOR inhibitor Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Texas Health Science Center San Antonio Johns Hopkins Claude D. Pepper Older Americans Independence Center US 2020-10-31 2022-10-31 HSC20200489H, NCT04482712, RAPA-CARDS Phase 1/Phase 2 Clinical Not yet recruiting 2 24 Months 20 Dean L Kellogg, MD, PhD 2020-08-05
Sero-Epidemiology of SARS-COV2 infection in the Autonomous city of Buenos Aires Coronavirus disease 19 infection anti-SARS-CoV-2 antibody test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ministerio de Salud de Ciudad Autónoma de Buenos Aires Argentina 2020-07-31 2020-10-31 NCT04482361, SEROEPIDEMIOLOGY COVID IN CABA Phase Not Applicable Not yet recruiting 1 3 Months 5400 Alejandro Macchia, MD, Daniel Ferrante, MD 2020-07-27
Survey about knowledge towards blood donation during COVID 19 pandemic Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Kasturba Medical College, Manipal Manipal Academy of Higher Education India 2020-07-21 CTRI/2020/07/026559 Phase Not Applicable Not yet recruiting 1 500 Deepika Chenna 2020-07-24
Neem Prophylaxis for Subjects Coming in Contact with COVID-19 Patients Coronavirus disease 19 infection Neem Capsules (Azadirachta indica) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Nisarga Biotech Pvt Ltd India 2020-07-21 CTP/NB/03/20, CTRI/2020/07/026560 Phase 3 Clinical Not yet recruiting 1 200 Dr Mohini Barde, Prof Tanuja Manoj Nesari 2020-07-24
Comparison of two devices for intubation in COVID simulated scenario in mannequin Coronavirus disease 19 infection Touren non channeled videolaryngosocpe with a styletted tube alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Medical Sciences India 2020-06-02 CTRI/2020/06/025522 Phase Not Applicable Not yet recruiting 1 50 Anju Gupta 2020-07-23
Safety and efficacy of Ayurvedic capsule in mild to moderate COVID-19 infection Coronavirus disease 19 infection, Influenza virus infection, Pneumonia Cap. IP alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) AMAI Charitable Trust India 2020-07-15 CTRI/2020/07/026570 Phase Not Applicable Not yet recruiting 1 60 Dr Hrishikesh Rangnekar, Dr Kishor H Suryawanshi, Dr Suresh Patankar 2020-07-31
VitD-COVID19: Vitamin D Supplementation in the Prevention and Mitigation of COVID-19 Infection Coronavirus disease 19 infection, Vitamin D deficiency Vitamin D3 alone Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Medical University of South Carolina Grassroots Health Nutrition Institute, ZRT Laboratory US 2020-07-31 2021-12-31 00099939, NCT04482673, VitD-COVID19 Phase 4 Clinical Recruiting 1 17 Months 140 Carol L Wagner, MD, Carole Baggerly, Jeffrey Korte, PhD, John E Baatz, PhD, Renee O Washington, MS 2020-08-05
CTC: CoYoT1 to California Coronavirus disease 19 infection, Diabetes mellitus CoYoT1 Care alone Adolescents (13-17 yrs), Young Adults (18-44 yrs) Children's Hospital of Los Angeles Rutgers University, University of Southern California US 2019-01-20 2020-12-31 CHLA-18-00488, CTC, NCT03793673 Phase Not Applicable Recruiting 1 23 Months 80 Alejandra Torres Sanchez, BA, Jaquelin J Flores Garcia, BS, Jennifer K Raymond, MD, MCR 2020-07-27
Universal versus Targeted School Screening for Adolescent Major Depressive Disorder Coronavirus disease 19 infection, Major depressive disorder universal screening arm alone Milton S. Hershey Medical Center Health Resources and Services Administration, Patient Centered Outcome Research Institute US 2018-07-01 2020-12-31 NCT03716869, R40MC31765, STUDY00010090 Phase Not Applicable Recruiting 1 30 Months 17300 Deepa Sekhar, MD 2020-07-27
Mindful Self Compassion for Combat Deployed Veterans With Moral Injury and Co-occurring PTSD-SUD Coronavirus disease 19 infection, Drug dependence, Post traumatic stress disorder Mindful Self-Compassion alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) VA Office of Research and Development Providence VA Medical Center, Rhode Island US 2019-05-21 2021-03-31 1I21RX002893-01A1, D2893-P, NCT03681288 Phase Not Applicable Recruiting 1 22 Months 24 Christy Capone, PhD, Erica M Eaton, PhD, Erica M. Eaton, PhD 2020-07-27
A phase II trial to evaluate COVID-EIG the potential treatment or prevention of SARS-CoV-2 infection (COVID-19) Coronavirus disease 19 infection COVID-EIG alone Emergent BioSolutions Inc Phase 2 Clinical Planned 0 2020-07-23
A phase II trial to evaluate COVID-HIG for the potential treatment or prevention of SARS-CoV-2 infection (COVID-19) Coronavirus disease 19 infection COVID-HIG alone Emergent BioSolutions Inc Phase 2 Clinical Planned 0 2020-07-23
COVID-19 and changes in the heart Cardiovascular disease, Coronavirus disease 19 infection, Viral pneumonia azithromycin alone, fluoroquinolone alone, hydroxychloroquine alone, sotalol alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sri Jayadeva Institute of Cardiovascular Sciences and Research India 2020-05-19 CTRI/2020/07/026698 Phase Not Applicable Not yet recruiting 1 3000 Dr Jayaprakash Shenthar 2020-07-28
EMPOWER: Enhancing and Mobilizing the POtential for Wellness and Emotional Resilience Among Surrogate Decision-Makers of ICU Patients Coronavirus disease 19 infection EMPOWER alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Weill Medical College of Cornell University Memorial Sloan-Kettering Cancer Center, National Cancer Institute, The New York Hospital Medical Center of Queens US 2017-07-12 2021-05-31 1610017622, EMPOWER, NCT03276559, R21CA218313 Phase Not Applicable Recruiting 3 46 Months 155 Holly G Prigerson, Ph. D., Martin Viola, M.A., Wendy Lichtenthal, Ph. D., Wendy Lichtenthal, PhD 2020-07-23
Infant Mental Health-Home Visiting Randomized Controlled Trial Coronavirus disease 19 infection, Psychiatric disorder Infant Mental Health-Home Visiting alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Michigan Michigan, State of, Health and Human Services, Department of Health and Human Services US 2017-10-12 2020-09-30 HUM00124224, NCT03175796 Phase Not Applicable No longer recruiting 1 35 Months 144 Katherine Rosenblum, PhD 2020-07-27
MBCT Delivered Via Group Videoconferencing for ACS Syndrome Patients With Depressive Symptoms Acute coronary syndrome, Coronavirus disease 19 infection, Depression Mindfulness-Based Cognitive Therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Massachusetts General Hospital US 2020-04-24 2021-01-02 2020P000045, NCT04231097 Phase Not Applicable Recruiting 1 8 Months 20 Christina Luberto, PhD, Christina M Luberto, PhD, Elyse Park, PhD, MPH 2020-07-27
PHOSP-COVID: Long-term follow up of adults hospitalized with COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Leicester United Kingdom Research & Innovation, University Hospitals of Leicester National Health Service Trust UK 2020-04-15 2046-12-31 CPMS 46443, IRAS 285439, ISRCTN10980107, PHOSP-COVID Phase Not Applicable Recruiting 44 320 Months 10000 Prof Brightling 2020-07-31
Ayurvedic Rasayana therapies Coronavirus disease 19 infection pranvir plus yasada rasayana Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Ayurved Rasayani India 2020-07-27 CTRI/2020/07/026700 Phase Not Applicable Not yet recruiting 2 200 Dr Avinash Kadam 2020-07-27
Management of endotracheal intubation in critically ill patients with novel coronavirus pneumonia (COVID-19) and clinical characteristics: a medical records based study Coronavirus disease 19 infection The First Affiliated Hospital of college of medicine Zhejiang University China 2020-07-15 2020-07-31 ChiCTR2000034852 Phase Not Applicable Recruiting 1 14 Fuquan Fang, Xianhui Kang 2020-07-27
Phase I/II Ascending Dose Study of Investigational SARS-CoV-2 Vaccine ARCT-021 in Healthy Adult Subjects Coronavirus disease 19 infection LUNAR-COV19 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Arcturus Therapeutics Inc, CTI Clinical Trial and Consulting Services Singapore 2020-07-31 2021-01-31 ARCT-021-01, NCT04480957 Phase 1/Phase 2 Clinical Not yet recruiting 1 6 Months 85 Connie Crowley, Jenny Low Guek Hong, MD, Michellore Aguilar, Steve Hughes, MD 2020-07-29
Knowledge, Attitude and Practice towards COVID-19 among Kerala Residents during the outbreak period:an online, cross-sectional survey Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Govt Medical College India 2020-08-01 CTRI/2020/07/026728 Phase Not Applicable Not yet recruiting 1 140 DR Venugopalan AK 2020-07-23
Mind Your Mate: The Mind Your Mate Study: A randomized, controlled trial of an online peer intervention to prevent mental health and substance use problems in adolescents Coronavirus disease 19 infection, Drug dependence, Psychiatric disorder Mind your Mate alone Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs) University of Sydney Australian Rotary Health Australia 2020-07-22 2021-12-17 ACTRN12620000753954, Mind Your Mate Phase Not Applicable Not yet recruiting 1 16 Months Dr Louise Birrell 2020-07-27
Scanning of lungs, heart and blood vessels by two different techniques using ultrasound in COVID-19 patients Coronavirus disease 19 infection ultrasonography alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Narayana Health India 2020-07-23 CTRI/2020/07/026701 Phase Not Applicable Not yet recruiting 1 80 Dr Muralidhar Kanchi 2020-07-27
Liver function test used as a tool to determine severity of COVD 19 pneumonia – A Prospective, observational study Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Medical Sciences India 2020-07-30 CTRI/2020/07/026727 Phase Not Applicable Not yet recruiting 1 100 Nishant Patel 2020-07-27
Structured online training program on specific COVID-19 Airway Management Coronavirus disease 19 infection Structured online training program alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) AIIMS Rishikesh India 2020-07-31 CTRI/2020/07/026715 Phase Not Applicable Not yet recruiting 1 1000 Bhavna Gupta 2020-07-23
Psychological Impact of COVID 19 on Healthcare Workers Anxiety disorder, Coronavirus disease 19 infection, Depression, Insomnia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) CARE Hospital India 2020-08-03 CTRI/2020/07/026714 Phase Not Applicable Not yet recruiting 1 100 Dr Harini Atturu 2020-07-27
A Phase I clinical trial of novel coronavirus pneumonia (COVID-19) mRNA Vaccine (BNT-162b1) in China Coronavirus disease 19 infection BNT-162b1 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry BioNTech RNA Pharmaceuticals GmbH, Jiangsu Province Centers for Disease Control and Prevention, Shanghai Fosun Pharmaceutical Industry Development Co Ltd China 2020-07-20 2020-12-31 ChiCTR2000034825 Phase 1 Clinical Recruiting 2 5 Months 144 Wang Wei, Zhu Fengcai 2020-08-07
Efficacy and safety of AYUSH 64 tablets in treating mild to moderate Covid 19 patients Coronavirus disease 19 infection AYUSH 64 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Central Council for Research in Ayurveda and Siddha India 2020-07-28 CTRI/2020/07/026705 Phase 1 Clinical Not yet recruiting 2 80 Dr Nataraj H R 2020-07-27
Covid-19 Pandemic: Economic Burden on Patients Operated for Traumatic Close Fractures Bone injury, Cancer, Coronavirus disease 19 infection, Degeneration elective surgery alone, operative fracture management intervention alone Aga khan University Pakistan 2020-03-16 2020-05-31 AKUPDE, NCT04482205 Phase Not Applicable Completed 1 2 Months 840 Pervaiz Hashmi, FCPS, shah fahad 2020-07-28
WW2COVID-19: Results of Emotional Support Activities During Hospital Admission With a Diagnosis of COVID19 Anxiety disorder, Coronavirus disease 19 infection nursing emotional supportive activity care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Corporacion Parc Tauli Spain 2020-09-30 2020-12-31 2020664, NCT04481477, WW2COVID-19 Phase Not Applicable Not yet recruiting 1 3 Months 450 Jordi Torralbas, MSc, Montserrat Montaña, PhD 2020-07-27
A clinical trial of HDT-301 for the prevention of Coronavirus disease 19 infection in healthy volunteers Coronavirus disease 19 infection HDT-301 alone COVID19 Spike glycoprotein inhibitor Healthy volunteers accepted American Association for the Advancement of Science, University of Washington HDT Bio, National Institutes of Health, Washington National Primate Research Center, Wellcome Trust - Burroughs Wellcome Fund Phase 1 Clinical Planned 0 2020-07-27
PREDICTCovid19: Development and Validation of a Prediction Model for the Transition From Mild to Moderate Form of COVID-19, Using Data From Chest CT Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Bordeaux France 2020-08-01 2020-10-31 CHUBX 2020/23, NCT04481620, PREDICTCovid19 Phase Not Applicable Not yet recruiting 7 3 Months 1315 Annaïg OZIER, MD, Arnaud BOURDIN, MD, PhD, Francois Laurent, MD, PhD, François CHABOT, MD, PhD, Gilbert FERRETTI, MD, PhD, Julien CASTEIGT, MD, Maeva Zysman, MD, Rémy GUILLEVIN, MD, PhD 2020-07-24
SEROCO: COVID-19 Serological Status of Hospital Staff Working or Not in the COVID-19 Sector Coronavirus disease 19 infection serological screening alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Limoges France 2020-08-15 2021-01-15 87RI20_0049/SEROCO, NCT04481529, SEROCO Phase Not Applicable Not yet recruiting 4 5 Months 1000 Julio BADIE, MD, Laurent FOURCADE, MD 2020-07-27
WWCOVID-19: Emotional Support and Stress Management in Patients Diagnosed With COVID-19 Anxiety disorder, Coronavirus disease 19 infection training video alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Corporacion Parc Tauli Spain 2020-09-30 2020-12-31 2020663, NCT04482023, WWCOVID-19 Phase Not Applicable Not yet recruiting 1 3 Months 150 Jordi Torralbas, MSc, Montserrat Montaña, PhD 2020-07-24
DigiVis: Self-testing Vision App for Telephone Consultations Coronavirus disease 19 infection, Vision disorder DigiVis visual acuity app alone, visual acuity self-test alone Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cambridge University Hospitals NHS Foundation Trust UK 2020-07-24 2021-01-01 IRAS196573, NCT04482387 Phase Not Applicable Not yet recruiting 1 5 Months 250 Louise Allen, Louise E Allen, MBBS MD, Nabil Uddin, Stephen E Kelleher 2020-07-24
Trial of Combination Therapy to Treat COVID-19 Infection Coronavirus disease 19 infection Variable regimens including doxycycline , ivermectin , vitamin C , vitamin D3 , zinc Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) ProgenaBiome Topelia Therpeutics US 2020-08-31 2023-01-31 NCT04482686, PRG-049 Phase 2 Clinical Not yet recruiting 1 29 Months 300 Jordan Daniels, MS, Sabine Hazan, MD, Thomas Borody, MD 2020-07-31
DART: Decitabine for Coronavirus (COVID-19) Pneumonia - Acute Respiratory Distress Syndrome (ARDS) Treatment Acute lung injury, Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia decitabine alone, standard of care alone Cytosine DNA methyltransferase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Johns Hopkins University US 2020-07-29 2021-07-31 DART, IRB00247544, NCT04482621 Phase 2 Clinical Recruiting 1 12 Months 40 Franco D'Alessio, M.D, Franco D'Alessio, M.D., Joby Mathew, DPT, MS, Katrina Bazemore 2020-07-24
A Trial of Aclaris Therapeutics, Inc ATI-450 in Patients With Moderate-severe Novel Coronavirus Disease 2019 (COVID-19) Coronavirus disease 19 infection, Hypoxia, Respiratory failure ATI-450 alone Adapter molecule crk inhibitor, MAPKAPK2 inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Kansas Medical Center Aclaris Therapeutics Inc US 2020-07-31 2022-07-31 IIT-2020-ATI-450-COVID-19, NCT04481685 Phase 2a Clinical Not yet recruiting 1 24 Months 36 Deepika Polineni, M.D., M.P.H, Gregory Gan, Kimberly Lovell 2020-07-24
RAPA-501-Allo Off-the-Shelf Therapy of COVID-19 Coronavirus disease 19 infection, Respiratory insufficiency RAPA-501 alone, standard-of-care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rapa Therapeutics Hackensack Meridian Health US 2020-09-30 2021-12-31 NCT04482699, RAPA-501-ALLO-COVID-19 Phase 1/Phase 2 Clinical Not yet recruiting 1 15 Months 88 Daniel Fowler, M.D., Jennifer Gough Clinical Regulatory Coordinator 2020-07-24
BIO-300 Oral Suspension in Discharged COVID-19 Patients Coronavirus disease 19 infection, Lung injury genistein (oral suspension, radiotherapy-induced toxicity/ in SARS-CoV-2 infection (COVID-19)/pulmonary fibrosis), Humanetics alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Humanetics Corp NYU Langone Health, National Institute of Allergy and Infectious Diseases US 2020-09-30 2022-07-31 272201800011C-P00005-9999-1, CL0105-01, NCT04482595 Phase 2 Clinical Not yet recruiting 1 22 Months 66 Michael D Kaytor, Ph.D., Rany Condos, MD 2020-07-27
A trial to evaluate SLV-213 for the treatment of patients with COVID-19 Coronavirus disease 19 infection SLV-213 alone Cysteine protease inhibitor Selva Therapeutics Inc Phase Not Applicable Planned 0 2020-07-28
PREPCOV: Efficacy of Pre-exposure Treatment With Hydroxychloroquine on the Risk and Severity of COVID-19 Infection Coronavirus disease 19 infection hydroxychloroquine alone, Variable regimens including azathioprine , hydroxychloroquine , methotrexate Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire de Toulouse France 2020-09-30 2020-09-30 2020-A01906-33, NCT04481633, PREPCOV, RC31/20/0186 Phase 4 Clinical Not yet recruiting 11 800 Adeline RUYSSEN-WITRAND, Pr, Anne-Laure FAUCHAIS, Pr, Arnaud CONSTANTIN, Pr, Carle PAUL, PR, Carle PAUL, Pr, Christina LIVIDEANU, DR, David RIBES, Dr, Dominique CHAUVEAU, Pr, Edouard LARREY, Dr, Estibaliz LAZARO, Pr, Francis GACHES, Dr, Georges-Philippe PAGEAUX, Pr, Gregory PUGNET, Pr, Guillaume MOULIS, Dr, Jean-François VIALLARD, Pr, Kim LY, Dr, Laurent ALRIC, Pr, Laurent SAILLER, Pr, Marie IRLES-DEPE, Dr, Martin MICHAUD, Pr, Mathieu VAUTIER, Dr, Pascal LEBRAY, Dr, Patrice CACOUB, P, Patrice CACOUB, Pr, Stéphanie FAURE, Dr, Victor DE LEDINGHEN, Pr 2020-07-27
Evaluation of Clinical Characteristics and Outcome of COVID-19 Pneumonia in Assiut University Hospital Coronavirus disease 19 infection, Viral pneumonia chest CT alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assiut University Egypt 2020-08-31 2021-09-30 NCT04481360, PRESENTATION OF COVID19 IN AUH Phase Not Applicable Not yet recruiting 1 13 Months 100 Marina Omil Saman, Marina Saman, Mostafa kamal, Safaa Mokhtar 2020-07-24
A trial to evaluate PneumoBlast for the treatment of patients with COVID-19 Coronavirus disease 19 infection PneumoBlast alone FibroGenesis US Phase Not Applicable Planned 1 2020-07-23
COVMASK: Novel Face Mask Sampling for COVID-19: A Diagnostic and Public Health Tool Coronavirus disease 19 infection 3D printed Polyvinyl alcohol face mask (University of Leicester) alone, face mask sampling alone Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Leicester University Hospitals of Leicester National Health Service Trust UK 2020-06-12 2025-06-30 0775, COVMASK, NCT04481646 Phase Not Applicable Recruiting 1 60 Months 630 Caroline Williams, MbChB, Manish Pareek, Manish Pareek, MBChB PhD 2020-07-24
PrimeRisk C-19: COVID-19 in primary care: assessment of risk factors and predictors for severe courses Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Styrian Academy of General Medicine Karl Landsteiner University of Health Sciences Austria 2020-07-16 1046/2020, DRKS00022448, PrimeRisk C-19 Phase Not Applicable Recruiting 1 300 Susanne Rabady 2020-07-28
MaZeCO: Patients with Breast Cancer in Times of COVID-19 Acute stress disorder, Breast tumor, Coronavirus disease 19 infection, Psychiatric disorder breast cancer-specific questionnaires alone, serum / plasma analysis alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Wurzburg Germany 2020-04-30 70/20 Amendment, DRKS00022507, MaZeCO Phase Not Applicable Recruiting 1 200 Catharina Bartmann 2020-07-28
GeZeCO: Birth in Times of COVID-19 Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression bio-sample analysis alone, questionnaires alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) University of Wurzburg Germany 2020-04-16 70/20, DRKS00022506, GeZeCO Phase Not Applicable Recruiting 1 300 Catharina Bartmann 2020-07-28
NEUROSIVIR: Safety, Tolerability and Pharmacokinetics of Inhaled Nanoparticle Formulation of Remdesivir (GS-5734) and NA-831 Coronavirus disease 19 infection, Neuritis, Neurodegenerative disease, Respiratory tract infection, Viral pneumonia remdesivir alone, traneurocin (Alzheimer's disease), NeuroActiva alone, remdesivir plus traneurocin (Alzheimer's disease), NeuroActiva AMPA receptor modulator, COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) NeuroActiva Inc US 2020-09-15 2021-03-31 NCT04480333, NEUROSIVIR, NEUROSIVIR Phase 1 Clinical Recruiting 1 6 Months 45 Brian Tran, MD, David Nguyen, MD, Lloyd Tran, PhD, Markku Kurkinen, PhD 2020-08-02
Survey of Coronavirus disease 2019(COVID-19) Coronavirus disease 19 infection fact-finding survey alone School of Medicine, Keio University Japan 2020-05-29 UMIN000041186 Phase Not Applicable Recruiting 1 2000 Koichi Fukunaga, Makoto Ishii 2020-07-28
Sexual Health and Problems During the Covid -19 Infection Coronavirus disease 19 infection, Sexual dysfunction questionaire alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Aljazeera Hospital Al-Azhar University Egypt 2020-06-11 2020-07-12 MARITAL HEALTH, NCT04427813 Phase Not Applicable Not yet recruiting 1 1 Month 400 Ahmed Elgazzar, M.D, Mahmoud Alalfy, PhD, Mahmoud Alalfy, master 2020-07-24
COVIDCIR: Complications and Mortality Following Emergency Digestive Surgery During the COVID-19 Pandemic Coronavirus disease 19 infection, Surgical procedure gastrointestinal surgery alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Universitari de Bellvitge Institut Investigació Biomèdica Bellvitge Spain 2020-03-01 2020-08-31 COVIDCIR, COVIDCIR, NCT04479150 Phase Not Applicable Recruiting 1 6 Months 3000 Javier Osorio, MD, PhD, Zoilo Madrazo, MD 2020-07-24
PLASMA: Therapeutic Plasmapheresis in Critically Ill Adult Patients With COVID-19 Confirmed Diagnosis Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia ABO compatible convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundacion Cardiovascular de Colombia Colombia 2020-08-01 2022-08-31 CEI-2020-01200, NCT04480632, PLASMA Phase 2 Clinical Not yet recruiting 1 25 Months 44 Claudia Colmenares, MD, Norma Serrano, MD 2020-07-24
Possible Predictors of Mortality Based on COVID-19 for Patients Under 50 Years Old: A Multicenter Experience of Istanbul Coronavirus disease 19 infection PCR alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Istanbul Bakirkoy Maternity and Children Diseases Hospital Turkey 2020-03-10 2020-07-14 KSSEAH--PPC, NCT04479137 Phase Not Applicable Completed 1 4 Months 5000 Ramazan Guven 2020-07-24
Bee-Covid: The Use of Brazilian Green Propolis Extract (EPP-AF) in Patients Affected by COVID-19 Coronavirus disease 19 infection Brazilian Green Propolis extract alone, antibiotic therapy alone, antiviral therapy alone, corticosteroid therapy alone, extracorporeal membrane oxygenation alone, invasive supplemental oxygenation alone, non-invasive supplemental oxygenation alone, renal replacement therapy alone, vasopressor support alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto D'Or de Pesquisa Hospital Sao Rafael Brazil 2020-06-02 2020-08-30 31099320.6.0000.0048, Bee-Covid, NCT04480593 Phase 2/Phase 3 Clinical Recruiting 1 2 Months 120 Marcelo Silveira, MD, PhD, Suzete Farias, MD, PhD 2020-07-30
Post COVID-19 Functional Status in Egypt Coronavirus disease 19 infection Assiut University Egypt 2020-07-01 2020-11-30 ASSIUTU16, NCT04479293 Phase Not Applicable Recruiting 1 5 Months 400 Aliaa AR Hussein, Aliae AR Mohamed Hussein 2020-07-24
Study to Evaluate the Safety and Efficacy of High Dose Intravenous Immune Globulin (IVIG) Plus Standard Medical Treatment (SMT) Versus SMT Alone in Participants in Intensive Care Unit (ICU) With Coronavirus Disease (COVID-19) Coronavirus disease 19 infection Gamunex alone, standard medical treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Grifols Therapeutics Inc, USA US 2020-07-31 2021-02-28 GC2007, NCT04480424 Phase 2 Clinical Not yet recruiting 1 7 Months 100 Elsa Mondou, MD, Rhonda Griffin, Simon Mahler, MD 2020-07-24
A clinical study of VLP vaccine for the potential treatment of Covid-19 Coronavirus disease 19 infection VLP vaccine (Vaxrex, COVID-19), Metaclipse Therapeutics alone Metaclipse Therapeutics 2021-12-31 Phase Not Applicable Planned 0 2020-07-29
The effect of Cyclosporine in prognosis and clinical improvement in patients with COVID-19 Coronavirus disease 19 infection, Respiratory tract infection ciclosporin, Novartis alone, routine treatment alone Calcineurin inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Hamadan University of Medical Sciences Iran 2020-07-22 IR.UMSHA.REC.1399.355, IRCT20200426047206N3 Phase 3 Clinical Recruiting 1 48 Behshad Naghshtabrizi, Dr Fariba Keramat, Saeed Bashirian, Salman Khazaei 2020-07-27
Safety, Tolerability, and Pharmacokinetics Study of Human Monoclonal Antibody BRII-196 Coronavirus disease 19 infection BRII-196 alone COVID19 Spike glycoprotein inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Brii Biosciences TSB Therapeutics (Beijing) CO.LTD China 2020-07-12 2021-03-31 BRII-196-001, NCT04479631 Phase 1 Clinical Recruiting 1 8 Months 12 Lili Chen, Yao Zhang 2020-07-27
Extracorporeal Blood Purification as a Treatment Modality for COVID-19 Blood clotting disorder, Coronavirus disease 19 infection, Inflammatory disease, Viral pneumonia Prismaflex oXiris system alone, continuous venovenous hemodiafiltration alone, continuous venovenous hemofiltration alone, extracorporeal blood purification therapy alone, oXiris (AN69ST) hemofilter (Baxter) alone, slow continuous ultrafiltration alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Zan Mitrev Clinic 2020-06-01 2021-07-01 EBPZ.357, NCT04478539 Phase Not Applicable Recruiting 0 13 Months 35 Dashurie Neziri, MD, Dijana Popevski, MD, Petar A Ugurov, MD, Rodney A Rosalia, PhD, Zan K Mitrev, MD 2020-07-23