Last updated: Aug 28, 2020 - 02:00 BST

Title Indication Intervention Actions PatientSelection Sponsor Collaborator Country StartDate EndDate Identifiers Phase Recruitment Status Sites Trial Duration Enrollment Count Contacts LastChanged
A phase I clinical trial of EPV-CoV-19 for potential prevention of COVID-19 Coronavirus disease 19 infection EPV-CoV19 alone EpiVax Inc, EpiVax Therapeutics Phase 1 Clinical Planned 0 2020-08-27
TRACE ll Prospective: Outcome in patients undergoing postponed elective surgery during the COVID-19 pandemic Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Amsterdam UMC The Netherlands Organisation for Health Research and Development Netherlands 2020-09-01 2021-12-31 NL8841, TRACE ll Prospective Phase Not Applicable Not yet recruiting 0 16 Months Carin Wensing 2020-08-27
The efficacy of methylprednisolone mini pulse on the treatment of COVID-19 patients admitted to intensive care unit Coronavirus disease 19 infection Standard treatment alone, methylprednisolone alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ardabil University of Medical Sciences Iran 2020-07-10 IR.ARUMS.REC.1399.206, IRCT20170716035126N4 Phase 3 Clinical No longer recruiting 0 60 Afshin Habibzadeh, Dr. Masoud Entezari Asl, Yousef Mohammadi Kebar 2020-08-27
TRACE ll Retrospective: Outcome in patients undergoing (postponed) surgery during the COVID-19 pandemic Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Maastricht UMC+ Netherlands 2020-08-31 2020-12-31 NL8837, TRACE ll Retrospective Phase Not Applicable Recruiting 0 4 Months 14000 Carin Wensing 2020-08-27
A clinical trial of Digid Cantisense SARS-CoV-2 test for COVID-19 infection Coronavirus disease 19 infection Digid Cantisense SARS-CoV-2 test alone Mainz University Hospital Germany Phase Not Applicable Not yet recruiting 0 2020-08-27
Treatment and Prevention of Acute Lung Injury (ALI) in Patients With SARS-CoV-2 Infection Acute lung injury, Coronavirus disease 19 infection, Inflammatory disease, Viral pneumonia daxdilimab alone Leukocyte Ig like receptor A4 modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Viela Bio US 2020-08-31 2021-03-31 NCT04526912, VIB7734.P1.S2 Phase 1 Clinical Not yet recruiting 0 7 Months 48 Daniel Falleroni, Gábor Illei, MD, PhD, MHS 2020-08-27
Efficacy and feasibility of an audio-based mindfulness intervention in reducing anxiety, depression and stress among people with the risk of anxiety and depression during the coronavirus disease 2019 (COVID-19) pandemic in Thailand Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression audio-guided mindfulness practice program alone, psychoeducation alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Faculty of Medicine Siriraj Hospital, Mahidol University Thailand 2020-09-15 TCTR20200819003 Phase 2 Clinical Not yet recruiting 1 70 Natee Viravan 2020-08-27
LF-COVID: Lactoferrin for Prevention of COVID-19 in Health Care Workers Coronavirus disease 19 infection bovine lactoferrin alone, standard personal protection measure alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Universidad Peruana Cayetano Heredia Peru 2020-09-01 2021-11-01 LF-COVID, NCT04526821, SIDISI 202110 Phase 2 Clinical Not yet recruiting 2 14 Months 336 Carlos Medina, MD, Eddie Angles, MD, Fernando Mejia, MD, Msc, Jorge Florez, MD, Meylin Aphang, MD, Msc, Theresa J Ochoa, MD, PhD 2020-08-27
Detecting SARS-CoV-2 in Tears Coronavirus disease 19 infection IHC staining alone, RT-PCR alone, biological sampling alone, tear collection alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Minnesota US 2020-09-30 2021-04-30 NCT04526769, STUDY00009512 Phase Not Applicable Not yet recruiting 1 7 Months 30 Corey Miller, Hossein Nazari, MD 2020-08-27
Study of COVID-19 DNA Vaccine (AG-0302-COVID19) Coronavirus disease 19 infection AG-0302-COVID19 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) AnGes MG Inc Japan 2020-08-31 2021-09-30 AG0302-COVID19-JN-01, NCT04527081 Phase 1/Phase 2 Clinical Recruiting 1 13 Months 30 AnGes, Inc. Clinical Development 2020-08-27
ISARIC: Case Fatalities in Hospitalized COVID-19 Patients in the UK Coronavirus disease 19 infection University of Edinburgh ISARIC UK 2020-02-24 2020-08-02 ISARIC, ISARIC-COVID-CF, NCT04527458 Phase Not Applicable Completed 1 5 Months 70000 Annemarie B Docherty, Ewen M Harrison, Rachel H Mulholland 2020-08-27
A phase Ib/II, randomized, double-blind, placebo-controlled study to assess the safety and efficacy of alvelestat in adult patients hospitalized with moderate to severe COVID-19 respiratory disease not yet receiving mechanical ventilation Coronavirus disease 19 infection, Respiratory disease alvelestat alone, standard of care alone Leukocyte elastase inhibitor Mereo BioPharma Group Ltd US 2020-08-25 Phase 1/Phase 2 Clinical Recruiting 1 15 Dr. J. Michael Wells 2020-08-27
Effect of donkey milk on the new COVID-19 Coronavirus disease 19 infection candy intake alone, donkey milk intake alone, drug treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Kerman University of Medical Sciences Iran 2020-09-05 IR.KMU.REC.1399.321, IRCT20161108030776N3 Phase Not Applicable Not yet recruiting 1 110 Abbas Pardakhty, Haleh Tajadini, Haleh tajadini, Mohadese Kamali 2020-08-27
IveprofCovid19: Effectiveness and Safety of Ivermectin for the Prevention of Covid-19 Infection in Colombian Health Personnel Coronavirus disease 19 infection ivermectin alone Chloride channel modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Javeriana University Colombia 2020-09-07 2020-12-16 EPI1JAVECALI, IveprofCovid19, NCT04527211 Phase 3 Clinical Not yet recruiting 1 3 Months 550 Eduar D. Echeverri, Dr., Eduar d Echeverri, Dr., Julian Santaella, PhD 2020-08-27
Study to Evaluate the Efficacy and Safety of AstroStem-V in Treatment of COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia AstroStem-V alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Nature Cell Co. Ltd. 2020-12-01 2022-04-01 ASVP1N2A-US, NCT04527224 Phase 1/Phase 2 Clinical Not yet recruiting 0 16 Months 10 2020-08-27
Extremely Premature Births During the Peak of the COVID-19 Pandemic: an International Study of the Active SafeBoosC III Departments Coronavirus disease 19 infection, Premature labor Newborn Infants (up to 5 months), Infants (6-23 months) Rigshospitalet, Denmark Denmark 2020-08-21 2020-09-13 NCT04527601, SAFEBOOSC COVID-19 ELGAN STUDY Phase Not Applicable Recruiting 0 280 Gitte Hahn, MD,PhD, Gorm Greisen, Gorm Greisen, MD, Prof, Marie Isabel Skov Rasmussen, MBBS 2020-08-27
The Effects of Filter During CPET on WOB and Aerosol Particle Concentrations Coronavirus disease 19 infection Vyair Vmax (Vyaire medical) alone, cardiopulmonary exercise testing alone, mask with in-line filter alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Rush University Medical Center Lundquist Institute US 2020-08-29 2020-12-31 CPET-001, NCT04526925 Phase Not Applicable Recruiting 1 4 Months 10 Jie Li, MS, Jie Li, PhD 2020-08-27
A clinical trial of UNI911for the treatment of Covid-19 Coronavirus disease 19 infection niclosamide (COVID-19), UNION therapeutics/ Institut Pasteur Korea alone S phase kinase associated protein 2 inhibitor UNION therapeutics Phase not specified Planned 0 2020-08-27
Study of Ensifentrine or Placebo Delivered Via pMDI in Hospitalized Patients With COVID-19 Coronavirus disease 19 infection ensifentrine alone, standard of care alone CFTR stimulator, PDE 3 inhibitor, PDE 4 inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Verona Pharma Inc Verona Pharma plc US 2020-08-31 2021-03-31 NCT04527471, RPL554-COV-201 Phase 2 Clinical Not yet recruiting 1 7 Months 45 Verona Pharma Inc 2020-08-27
Heat Shock Protein Inhibitor- MPT-0B640 for COVID-19 Infection Coronavirus disease 19 infection MPT-0B64 alone Heat shock protein HSP90 alpha inhibitor, Heat shock protein HSP90 beta inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Joseah Biopharma Co Ltd 2020-12-31 2021-12-31 JO201901-02, NCT04526717 Phase 1 Clinical Not yet recruiting 0 12 Months 15 Ethan Seah, Haein Kim, JiHye Choe 2020-08-27
A human trial of SAR-CoV-2 vaccine (recombinant protein, COVID-19)for the prevention of COVID-19 Coronavirus disease 19 infection SAR-CoV-2 vaccine (recombinant protein, COVID-19), Sichuan University/Zhejiang Teruisi Pharmaceutical/Chengdu Institute of Biological Products alone Sichuan University Phase Not Applicable Planned 0 2020-08-27
COLCOVIDBD: Colchicine in Moderate Symptomatic COVID-19 Patients: Double-Blind, Randomized, Placebo-Controlled Trial to Observe the Efficacy Coronavirus disease 19 infection colchicine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dhaka medical college Bangladesh 2020-07-14 2020-12-31 COLCOVIDBD, NCT04527562, U1111-1255-3541 Phase 2 Clinical Recruiting 1 5 Months 300 Motlabur Rahman, MBBS, FCPS,FACP, Motlabur Rahman, MBBS,FCPS,FACP, Mujibur Rahman, MBBS,MD,FCPS, Ponkaj Datta, MBBS, FCPS 2020-08-27
CoVIHDis: Differences in Immune Response Among HIV-1-infected Individuals With Previous or Current COVID-19 Coronavirus disease 19 infection, HIV-1 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Asociacion para el Estudio de las Enfermedades Infecciosas Spain 2020-09-01 2021-09-30 CoVIHDis, EC 273/20, NCT04526977 Phase Not Applicable Not yet recruiting 1 13 Months 90 Alejandro Vallejo, PhD, Jose L Casado, PhD 2020-08-27
A Patient Perspective Survey on Masking or De-Masking the Medical Staff amid COVID-19 Pandemic Coronavirus disease 19 infection Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Maroondah hospital Box Hill Hospital Australia 2020-03-23 ACTRN12620000808943, U1111-1256-1499 Phase Not Applicable Recruiting 2 500 Dr Aihua Wu 2020-08-27
An Open, Non-comparative Study of the Efficacy and Safety of Aprotinin in Patients Hospitalized With COVID-19 Coronavirus disease 19 infection, Lung injury, Viral pneumonia Gordox alone, standard of care alone, Gordox plus favipiravir RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Aviron Pharma LLC Russian Federation 2020-06-11 2020-08-31 COVID-APR-01, NCT04527133 Phase 2 Clinical No longer recruiting 1 2 Months 30 Elena Simakina, MD 2020-08-27
Clinical Course and Treatment of COVID-19 Inpatients in Hospital Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Wissenschaftliches Institut Bethanien e.V. Germany 2020-08-01 2021-08-31 NCT04527497, WI_20-1294 Phase Not Applicable Recruiting 1 13 Months 50 Anja Pietzke-Calcagnile, Dr., Marcel Treml, Dr., Simon Herkenrath, Winfried Randerath, Prof. Dr. 2020-08-27
Effect of traditional medicine protocol included Astraglus gossypinus with Ferula assa capsule on improvement of COVID-19 outpatients symptoms Coronavirus disease 19 infection standard Corona treatment alone, Astragalus gossypinus syrup plus Ferula assafoetida syrup Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kerman University of Medical Sciences Iran 2020-08-10 IR.KMU.REC.1399.275, IRCT20101219005416N3 Phase Not Applicable Recruiting 1 120 Abas Pardakhti, Haleh Tajadini 2020-08-27
Effect of a Brief Mood Training Program on Anxiety and Depression Arising from COVID-19-Related Stress Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression positive mood training alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) UNSW Sydney National Health and Medical Research Council Australia 2020-09-30 ACTRN12620000811909p Phase Not Applicable Not yet recruiting 8 Prof Richard Bryant 2020-08-27
A clinical trial of CT-P59 for the treatment of Covid-19 Coronavirus disease 19 infection CT-P59 alone COVID19 Spike glycoprotein inhibitor, Moesin modulator Celltrion Inc South Korea Phase Not Applicable Status not specified 1 2020-08-27
A phase I/II clinical trial of injector type GX-19 covid vaccine Coronavirus disease 19 infection GX-19 alone Gangnam Severance Hospital, Genexine Co Ltd, Severance Hospital South Korea Phase 1/Phase 2 Clinical Status not specified 2 2020-08-27
BRAINSTEM-COV: Brainstem Dysfunction in COVID-19 Critically Ill Patients: a Prospective, Observational Study Brainstem disease, Coronavirus disease 19 infection electrocardiography alone, electroencephalography alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-08-31 2021-05-31 2020-A01559-30, APHP200644, BRAINSTEM-COV, NCT04527198 Phase Not Applicable Not yet recruiting 2 9 Months 40 Adèle BELLINO, Bertrand HERMANN, MD, PhD, Bertrand HERMANN, MD,PhD, Sarah BENGHANEM, MD 2020-08-27
PICOV: Influence of Prior Infection With COVID-19 on Occurrence of Influenza-like Illness or Acute Respiratory Infection Coronavirus disease 19 infection, Influenza virus infection, Respiratory syncytial virus infection, Respiratory tract infection multiplex assay alone, qRT-PCR test alone, serology testing alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sciensano Institute of Tropical Medicine, Belgium, Mensura EDPB, Universite Libre de Bruxelles Belgium 2020-09-01 2021-05-30 NCT04527614, PICOV, PICOV2021 Phase Not Applicable Not yet recruiting 1 8 Months 2000 Maria Gpossens 2020-08-27
A Phase I/II, randomized, placebo-controlled, multicenter study to evaluate the safety and immunogenicity of COVID-19 Vaccine in Healthy Adults Coronavirus disease 19 infection RBD SARS-CoV-2 HBsAg VLP vaccine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) ACCELAGEN PTY LTD, Serum Institute of India Ltd Australia 2020-08-17 ACTRN12620000817943p Phase 1/Phase 2 Clinical Not yet recruiting 1 280 A/Prof Paul Griffin, Mr Greg Plunkett 2020-08-27
A post-registration, randomized, double-blind, placebo-controlled multicenter clinical study of the efficacy, immunogenicity and safety of the Sputnik V vaccine Coronavirus disease 19 infection Sputnik V alone COVID19 Spike glycoprotein modulator Gamalei Institute of Epidemiology and Microbiology, Russian Direct Investment Fund Russian Federation Phase 4 Clinical Not yet recruiting 1 40000 2020-08-27
COFIT registry: Registry of Covid 19 survivors for Fitness, exercise impairment and exercise Training Coronavirus disease 19 infection Maxima Medisch Centrum Veldhoven Netherlands 2020-08-14 2022-08-14 COFIT registry, NL8836 Phase Not Applicable Recruiting 0 24 Months 200 Martijn van Hooff 2020-08-27
ICU-VR after COVID-19: Intensive Care Unit specific Virtual Reality (ICU-VR) to improve psychological impairments in survivors of COVID-19: a multicenter, randomized, controlled trial Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder Intensive Care Unit Specific Virtual Reality therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Erasmus University Medical Center Rotterdam BeterKeten, Franciscus Gasthuis & Vlietland, Stichting Coolsingel 2020-06-29 2021-12-31 ICU-VR after COVID-19, NL8835 Phase Not Applicable Recruiting 0 18 Months 80 Johan Vlake 2020-08-27
C-SMART (Arm 3): COVID-19 Prevention and Treatment in Cancer.Arm 3: treatment among cancer patients with moderate COVID-19 infection Coronavirus disease 19 infection IFN-alpha alone, lenzilumab alone, selinexor alone Exportin 1 inhibitor, GM-CSF ligand inhibitor, Immunoglobulin G1 modulator, Immunoglobulin kappa modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Peter MacCallum Cancer Centre Australian Government Australia 2020-09-01 ACTRN12620000841976, C-SMART (Arm 3), U1111-1256-8488 Phase 3 Clinical Not yet recruiting 5 126 Dr Michelle Yong, Mr Ronan Burder, Prof Monica Slavin 2020-08-27
Crit-Cov-U: Prospective validation of a proteomic urine test for early and accurate prognosis of critical course complications in patients with SARS-CoV-2 infection Coronavirus disease 19 infection proteomic urine test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hannover Medical School Deutsche Forschungsgemeinschaft (DFG), German Federal Ministry of Education and Research Germany, Austria 2020-08-01 Crit-Cov-U, DRKS00022495, EK-BR-88/20-1 Phase Not Applicable Recruiting 2 1000 Heiko von der Leyen, Joachim Beige 2020-08-27
Prediction Models for Diagnosis and Prognosis of Severe COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure, Shock, Viral pneumonia artificial intelligence model alone, computed tomography alone Second Affiliated Hospital ZheJiang University College of Medicine China 2020-02-20 2020-08-20 2020-12020001231, NCT04525287 Phase Not Applicable Recruiting 1 6 Months 1000 Luopei Wei, Minming Zhang, PHD 2020-08-26
Methylene Blue in COVID-19 Coronavirus disease 19 infection, Respiratory failure corticosteroid therapy alone, Metiblo, Oterop company plus lopinavir + ritonavir HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shiraz University of Medical Sciences Iran 2020-08-15 IR.SUMS.REC.1399.016, IRCT20090701002113N2 Phase 3 Clinical Recruiting 2 260 Jamshid Roozbeh, Siavash Gholami, Yunos Ghasemi 2020-08-27
Wide Scale Monitoring for Acute Respiratory Infection Using a Mobile-based Study Platform Coronavirus disease 19 infection, Influenza virus infection, Respiratory tract infection mobile-based study platform app (Google Inc) alone, wide scale monitoring alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Boston Children's Hospital Google Inc US 2020-09-30 2021-09-30 IRB-P00036213, NCT04525118 Phase Not Applicable Not yet recruiting 1 12 Months 100000 Emily Cohn, MPH, John Brownstein, Kara Sewalk, MPH 2020-08-26
A Phase I Study of the EmitBio RD19 Device to Prevent SARS-CoV-2 and COVID-19 Coronavirus disease 19 infection EmitBio RD19 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) KNOW Bio LLC M3-Wake Research Associates Carolina Phase I Clinical Trial Unit, TAB Clinical US 2020-08-31 2020-10-01 NCT04525976, RD19-01-3Q20 Phase Not Applicable Not yet recruiting 1 1 Month 25 Aubrey Farray, John G McNeil, MD MPH PHD, Lisa Cohen, DO, Lisa Eckert, PA, Lynn A Bagylos, MSN 2020-08-26
Hand Sanitizer Effects on the Skin Barrier Atopic dermatitis, Coronavirus disease 19 infection hand sanitizer alone, hand washing alone, skin tape strip test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) National Jewish Health US 2020-08-18 2021-08-20 3030005053, HS 0720, NCT04525521 Phase Not Applicable Recruiting 1 12 Months 40 Jessica Hui, Jessica Hui, MD 2020-08-26
COVIDSTORM: Use of Tocilizumab in the inflammatory phase of COVID-19 / new coronavirus disease Coronavirus disease 19 infection tocilizumab (intravenous), Roche/Chugai alone IL-6 receptor antagonist, IL-6 receptor modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Turku University Hospital Finland 2020-06-17 2020-002039-31, COVIDSTORM, covidstorm Phase 3 Clinical Recruiting 0 90 2020-08-27
Rapid Screening Test for COVID-19 Antibodies in Healthcare Workers Coronavirus disease 19 infection AAZ rapid test alone, ELISA test alone, blood sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Groupe d'Etude sur le Risque d'Exposition des Soignants aux Agents Infectieux France 2020-04-25 2020-10-25 GERES20200409, ID RCB 2020-A01031-38, NCT04525417 Phase Not Applicable Recruiting 1 6 Months 100 Charlotte Charpentier, MD, Elisabeth Bouvet, MD, Gerard Pellissier, PhD 2020-08-26
ThalaCoV: Frequency of COVID-19 Antibodies in Patients With Hereditary Hematological Diseases Coronavirus disease 19 infection, Diamond Blackfan anemia, Hematological disease, Sickle cell anemia, Thalassemia intermedia, Thalassemia major SARS-CoV-2 S1/S2 IgG analysis alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Milano-Bicocca Italy 2020-07-14 2020-10-30 NCT04526405, THALACOV, ThalaCoV Phase Not Applicable Recruiting 6 3 Months 81 Alberto Piperno, Prof, Sara Pelucchi, Dr.ssa 2020-08-26
Morphological Abnormalities of the Olfactory Bulb on MRI and Olfactometry in Anosmic Versus Normosmic COVID-19 Patients Coronavirus disease 19 infection, Olfaction disorder anterior rhinoscopy alone, brain MRI alone, nasofibroscopy alone, olfactometry test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopital Foch Raymond Poincare University Hospital France 2020-09-06 2021-09-06 2020-0057, NCT04526054 Phase Not Applicable Not yet recruiting 2 12 Months 30 Elisabeth Hulier-Ammar, Dr, Jerome Lechien, Dr, Robert-Yves Carlier, Pr, Stephane Hans, Pr 2020-08-26
CHDR2029: In vitro characterization of the immune response of recovered COVID-19 patients and healthy controls to SARS-CoV-2 Coronavirus disease 19 infection blood sampling alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) ISA Pharmaceuticals BV 2020-08-10 2020-09-30 CHDR2029, NL74814.058.20, NL8821 Phase Not Applicable Not yet recruiting 0 1 Month 14 I.M.C. de Visser-Kamerling 2020-08-26
ALCOVID: Assessment of Long-term Impact Post COVID-19 for Patients and Health Care Professionals of the European Hospital Coronavirus disease 19 infection serology test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hôpital Européen Marseille France 2020-08-17 2022-10-31 2020- A01647-32, ALCOVID, NCT04525911 Phase Not Applicable Not yet recruiting 1 26 Months 258 Hervé PEGLIASCO, Myriam BENNANI 2020-08-26
Preparations of Dutch Emergency Departments for the SARS-COV-2 outbreak Coronavirus disease 19 infection Zuyderland Medical Center, Heerlen Netherlands 2020-07-29 2020-10-01 NL8818, Z2020149 Phase Not Applicable Recruiting 0 2 Months 84 Rory O'Connor 2020-08-27
The Effect of COVID-19 on Patient Outcomes Among Operated Patients Coronavirus disease 19 infection surgery alone Karolinska Institutet Sweden 2020-03-01 2020-12-31 COVIDKIRURGI, NCT04525716 Phase Not Applicable Recruiting 1 10 Months 2000 Andreas Älgå, Andreas Älgå, MD, PhD, Gabriel Sandblom, MD, PhD 2020-08-26
Endothelial Function and COVID-19 Coronavirus disease 19 infection EndoPat system, Itamar alone, Peripheral arterial tonometry alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Clinico San Carlos Mayo Clinic, Minnesota Spain, US 2020-06-03 2020-09-30 20/451, NCT04525443 Phase Not Applicable Recruiting 2 3 Months 100 Alejandro Travieso, MD, Eduardo Martinez, MD, Hernan Mejia-Renteria, M.D, Hernan Mejia-Renteria, MD, Hernán Mejía-Rentería, MD, Javier Escaned, MD, PhD 2020-08-26
Lower morbidity and mortality in COVID-19 patients admitted in a dedicated COVID Hospital of Odisha - a radiological perspective Coronavirus disease 19 infection Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kalinga Institute of Medical Sciences India 2020-08-20 CTRI/2020/08/027247 Phase Not Applicable Not yet recruiting 1 1500 Dr Roopak Dubey, Dr col Kamal Kumar sen 2020-08-27
VitCov: High Dose Vitamin-D Substitution in Patients With COVID-19: a Randomized, Controlled, Multicenter Study Coronavirus disease 19 infection, Vitamin D deficiency standard treatment alone, vitamin D3 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kantonsspital Baselland Switzerland 2020-09-01 2021-06-30 2020-01401, NCT04525820, VitCov Phase Not Applicable Not yet recruiting 3 10 Months 80 Fabienne Jaun, BScN, Jörg D Leuppi, Professor, Michael Brändle, Professor, Philipp Schütz, Professor, Prof. Dr. Jörg Leuppi 2020-08-27
Role of Tocilizumab in COVID-19 Pneumonia patients Coronavirus disease 19 infection, Viral pneumonia tocilizumab alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gujarat Cancer Society Medical college hospital and research centre India 2020-09-01 CTRI/2020/08/027246 Phase Not Applicable Not yet recruiting 1 40 Dr Jay Shah, Dr Shaila Shah 2020-08-26
MOIST: Multi-Organ Imaging With Serial Testing in COVID-19 Infected Patients Coronavirus disease 19 infection, Fatty liver disease, Heart injury, Inflammatory disease, Liver injury blood test alone, cognitive testing alone, high-sensitivity troponin testing alone, multi-organ MRI scan alone, olfaction testing alone, spiromety alone, walk test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Alberta Canadian VIGOUR Centre Canada 2020-09-01 2021-09-01 MOIST, NCT04525404, PRO00102389 Phase Not Applicable Not yet recruiting 1 12 Months 228 Ian Paterson, MD, Karin Kushniruk, RN, PhD 2020-08-26
Behavioral and emotional difficulties of school going children during COVID times Coronavirus disease 19 infection Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) Lokopriya Gopinath Bordoloi Regional Institute of Mental Health India 2020-08-29 CTRI/2020/08/027244 Phase Not Applicable Not yet recruiting 1 3500 Dr Subhashish Nath 2020-08-26
International phase II/III trial of GRAd-COV2 against covid-19 infection Coronavirus disease 19 infection GRAd-COV2 alone COVID19 Spike glycoprotein modulator ReiThera Srl Phase 2/Phase 3 Clinical Planned 0 2020-08-26
Identifying the factors that alters the recovery time of the COVID-19 patients Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sri Ramachandra Hospital, Chennai India 2020-09-11 CTRI/2020/08/027243 Phase Not Applicable Not yet recruiting 1 500 T Gayathri 2020-08-27
Study of Radiotherapy practice during Corona Pandemic Cancer, Coronavirus disease 19 infection radiotherapy alone Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tata Memorial Hospital India 2020-08-28 CTRI/2020/08/027226 Phase Not Applicable Recruiting 1 2500 Jai Prakash Agarwal 2020-08-27
COVID-19 prevalence during pregnancy and pregnancy outcomes in low resource settings Coronavirus disease 19 infection blood sampling alone Female, Young Adults (18-44 yrs) Eunice Kennedy Shriver National Institute of Child Health & Human Development Global Network for Women's and Children's Health Research Kenya, Congo, The Democratic Republic of the, India, Zambia, Pakistan, Bangladesh 2020-08-01 CTRI/2020/08/027218 Phase Not Applicable Not yet recruiting 0 16000 Dr Archana Patel, Dr Shivaprasad S Goudar 2020-08-27
SCION: A backdated comparison of patients operated before the COVID-19 pandemic versus those operated during the COVID_19 pandemic Coronavirus disease 19 infection, Infectious disease cancer surgery alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tata Memorial Centre India 2020-08-19 CTRI/2020/08/027210, SCION Phase Not Applicable Not yet recruiting 1 3000 Dr Gouri Pantvaidya 2020-08-27
POMPCO: A survey to collect vital parameters and symptoms of participants at risk of COVID19 Coronavirus disease 19 infection wearable health device alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) INNOWEAR TECHNOLOGIES PRIVATE LIMITED India 2020-08-26 CTRI/2020/08/027323, POMPCO Phase Not Applicable Not yet recruiting 2 100 Dr Manoj Yadav, Megha Patel 2020-08-27
A study regarding knowledge, attitude and practice about immunity boosting measures for prevention of COVID-19 infection among healthcare workers at tertiary care hospital Coronavirus disease 19 infection Immunity Boosting measures for self-care alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Bhaikaka University India 2020-09-15 CTRI/2020/08/027359 Phase Not Applicable Not yet recruiting 1 300 Dr Manisha Gohel 2020-08-27
To assess the clinical efficacy of Ayurvedic interventions in managing asymptomatic to mild cases of COVID-19 Coronavirus disease 19 infection Broncho-T Granules alone, Variable regimens including Agasthya Haritaki , Anu taila , Ayush-64 Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shri Dhanwantry Ayurvedic college and hospital India 2020-08-25 CTRI/2020/08/027346 Phase 2/Phase 3 Clinical Not yet recruiting 0 60 Shikha Chaudhary 2020-08-27
To Evaluate Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of DWRX-2003 Against COVID-19 Coronavirus disease 19 infection repositioned niclosamide (refractory lung disease/COVID-19), Daewoong Pharmaceutical/Institut Pasteur Korea alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Daewoong Pharmaceutical Co Ltd 2020-08-31 2020-12-31 DWJ1516101_INDIA, NCT04524052 Phase 1 Clinical Not yet recruiting 0 4 Months 32 2020-08-27
mCCP: Safety of convalescent plasma (CVP) drawn from mild symptomatic COVID-19 patients Coronavirus disease 19 infection Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Medical Sciences China 2020-08-21 CTRI/2020/08/027285, mCCP Phase Not Applicable Recruiting 1 100 Diptiranjan Rout 2020-08-25
LLLT Treatment of Lung Inflammation in COVID-19 Coronavirus disease 19 infection, Lung inflammation, Respiratory distress syndrome, Viral pneumonia Non-invasive low-level laser therapy treatment alone, Standard care therapy alone, UltraSlim red/IR LED device alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ward Photonics LLC US 2020-07-26 2021-01-31 CP19-02, NCT04524715 Phase Not Applicable Recruiting 2 6 Months 64 Gina M Brewer, Patty J Lee, MD, Randal Horsley, DC, Randal Horsley, DO, Rober H Burke, MD 2020-08-26
A study to evaluate the efficacy and safety of Aceinavir combined with supportive Standard of Care (SoC) in hospitalized patients with moderate coronavirus disease (COVID-19) Coronavirus disease 19 infection Aceinavir alone, Standard of Care (SoC) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dyuthi Biosciences Private Limited India 2020-08-28 CTRI/2020/08/027284, TG/PRO/CLI/035 Version 2.0 Phase 2 Clinical Not yet recruiting 1 44 Dr Shashank Acharya, Dr Sruthi Nambiar, Dr Vishal Rao 2020-08-25
UNC CCP RCT: COVID-19 Antibody Plasma Research Study in Hospitalized Patients Coronavirus disease 19 infection, Gastrointestinal disease, Respiratory disease convalescent COVID-19 plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of North Carolina US 2020-08-17 2021-05-31 20-1544, IGHID 12021, NCT04524507, UNC CCP RCT Phase 2 Clinical Recruiting 1 9 Months 56 Brian Gurney, ACNP, FNP, David M Margolis, MD, David van Duin, MD, PhD, JoAnn Kuruc, RN, MSN, Luther A Bartelt, MD 2020-08-25
A clinical trial to evaluate the medicinal efficacy and safety of ayurvedic kit in COVID-19 positive patients Coronavirus disease 19 infection Ayur Raksha capsules plus Ayur Raksha choorna Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) M/S AYURASHRAMA PHARMACEUTICALS India 2020-08-24 CTRI/2020/08/027283 Phase 2/Phase 3 Clinical Not yet recruiting 1 30 Dr BHAVYA DARSHINI M, Dr C R JAYANTHI, Dr VISHWA SANTHOSHA BHARATHI 2020-08-25
Clinical Trial of Ivermectin Plus Doxycycline for the Treatment of Confirmed COVID-19 Infection Coronavirus disease 19 infection antibiotic therapy alone, antihistamine therapy alone, drug therapy alone, oxygen therapy alone, vitamin intake alone, Variable regimens including doxycycline (Popular pharmaceutical limited) , ivermectin (Popular pharmaceutical limited) , low-molecular weight heparin , paracetamol Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dhaka medical college Bangladesh 2020-06-01 2020-08-30 ERC-DMC/ECC/2020/117, NCT04523831 Phase 3 Clinical Recruiting 1 2 Months 400 Mahmud Reaz, FCPS, Mahmud Reaz, FCPS, MD, Mahmud Reaz, FCPS. MD, Rahman Md Mujibur, FCPS 2020-08-25
Prophylactic Ivermectin in COVID-19 Contacts Coronavirus disease 19 infection ivermectin alone Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Government Institute of Medical Sciences, Greater Noida India 2020-08-31 CTRI/2020/08/027282 Phase 3 Clinical Not yet recruiting 1 180 Dr Hariom Kumar Solanki, Dr Rambha Pathak, Dr Saurabh Srivastava 2020-08-26
SPARTACOS-19 trial: Re-purposing of Anti HCV drugs for the treatment of COVID-19 disease Coronavirus disease 19 infection Daclatasvir/ Sofosbuvir alone, sofosbuvir + ledipasvir (fixed-combination/oral, HCV/HBV), Gilead alone Hepatitis C virus NS5B polymerase inhibitor, Hepatitis C virus protein NS5A inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Pt. B.D. Sharma PGIMS India 2020-08-31 CTRI/2020/08/027345, SPARTACOS-19 trial Phase 3 Clinical Not yet recruiting 1 175 Dhruva Chaudhry 2020-08-25
Ivermectin as a possible treatment for COVID-19 Coronavirus disease 19 infection ivermectin alone Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences Patna India 2020-08-28 CTRI/2020/08/027225 Phase 2 Clinical Not yet recruiting 1 90 Ravi Kirti 2020-08-27
Assessing the fear and worries associated with COVID-19 in out-patient population of a hospital Anxiety disorder, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Gujarat Cancer Society Medical college hospital and research centre India 2020-08-31 CTRI/2020/08/027281 Phase Not Applicable Not yet recruiting 1 250 Parth Shah 2020-08-25
To observe the effect of Ayurvedic medicine (Ashwagandha and Shunti) for the treatment of COVID-19 Coronavirus disease 19 infection Ashwagandha tablet plus Shunti Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Central Council for Research in Ayurvedic Sciences India 2020-08-25 CTRI/2020/08/027224 Phase 2/Phase 3 Clinical Not yet recruiting 0 60 Dr Harbans Singh, Dr Sumit Shrivastva 2020-08-27
The study of occurrence, distribution and control measures of COVID-19 among police personnel during pandemic in Pune city, Maharashtra Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) B.J.Medical College and Civil Hospital India 2020-08-20 CTRI/2020/08/027275 Phase Not Applicable Not yet recruiting 1 200 Dr Ganesh Jagdale, Dr Malangori A Parande 2020-08-25
CARDY-COVID: Cardiac Dysfunction in Critically Ill Patients Infected With COVID-19 Coronavirus disease 19 infection, Heart disease Echocardiography alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sahlgrenska University Hospital Sweden 2020-04-20 2020-09-30 CARDY-COVID, CARDY-COVID, NCT04524234 Phase Not Applicable Recruiting 3 5 Months 100 Jacob Holmqvist, MD, Jonatan Oras, MD, PhD 2020-08-26
Unani formulations for prevention of COVID-19 infection Coronavirus disease 19 infection Infuza alone, Kulzam alone, Infuza plus Kulzam Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hamdard Laboratories India 2020-08-24 CTRI/2020/08/027222 Phase 2 Clinical Not yet recruiting 0 200 Dr Kailash Chandra, Dr Mridu Dudeja, Dr Naushad Rana, Mr Ayan Kumar Das 2020-08-27
A CBT-based Mobile Intervention as First Line Treatment for Adolescent Depression During COVID-19 Anxiety disorder, Coronavirus disease 19 infection, Depression Limbix Spark digital mobile application (Limbix Health, Inc) alone, cognitive behavioral therapy alone Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs) Limbix Health Inc US 2020-07-20 2020-12-31 LIMBIX SPARK 02, NCT04524598 Phase Not Applicable Recruiting 1 5 Months 410 Aarthi Padmanabhan, PhD, Aarthi Padmanabhan, Phd, Jessica Lake, PhD, Marisa Cruz, MD 2020-08-25
Study to assess the usefulness, effectiveness and feasibility for future use of the consultations done using telephone/whatsapp in rheumatic diseases during CoVID-19 pandemic Coronavirus disease 19 infection, Musculoskeletal disease Tele-consultation alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences India 2020-09-01 CTRI/2020/08/027324 Phase Not Applicable Not yet recruiting 1 5000 Ranjan Gupta 2020-08-27
Study of Descartes-30 in Acute Respiratory Distress Syndrome Coronavirus disease 19 infection, Respiratory distress syndrome Descartes-30 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cartesian Therapeutics US 2020-08-20 2022-09-25 DC30-1A, NCT04524962 Phase 1/Phase 2 Clinical Not yet recruiting 2 25 Months 30 Adam S Chowdhury, MD, MBA, Bruce D Levy, MD, Ryan Kennedy, MD 2020-08-26
Oral Camostat Compared With Standard Supportive Care in Mild COVID-19 Patients Coronavirus disease 19 infection Standard of care treatment alone, camostat mesylate alone Serine protease inhibitor, Transmembrane serine protease 2 inhibitor, Trypsin inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Stanford University US 2020-08-31 2021-04-30 56029, COPS-2002, NCT04524663 Phase 2 Clinical Not yet recruiting 1 8 Months 120 Julie Parsonnet, MD 2020-08-26
Prevalence and Outcomes of Olfactory and Gustatory Dysfunctions in Patients With COVID-19 Coronavirus disease 19 infection, Dysgeusia, Dysomia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ain Shams University Egypt 2020-07-11 2020-11-30 FMASUP46A/2020, NCT04524754 Phase Not Applicable Recruiting 1 4 Months 218 Fatma S Ebeid, MD, Mohamed Shehata Taha, ethical committee 2020-08-26
How does the COVID-19 quarantine affect physical activity levels? Coronavirus disease 19 infection physical activity alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Jobu hospital for respiratory diseases Japan 2020-09-01 UMIN000041526 Phase Not Applicable Not yet recruiting 1 400 Keita Takagawa 2020-08-27
COVID19-OR (SARS-CoV-2): Observation, Risk And Recovery Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Western Sussex Hospitals NHS Trust UK 2020-05-05 2022-05-08 20/YH/0157, COVID19-OR (SARS-CoV-2), NCT04524520 Phase Not Applicable Recruiting 1 24 Months 30 Dr Christina Koulouglioti, Dr Luke Hodgson, Dr Luke hodgson 2020-08-27
The effect of Atorvastatin therapy in COVID-19 Coronavirus disease 19 infection Variable regimens including atorvastatin , hydroxychloroquine , lopinavir + ritonavir HIV protease inhibitor, HMG CoA reductase inhibitor North Khorasan University of Medical Sciences Iran 2020-08-20 IR.NKUMS.REC.1399.035, IRCT20190831044653N5 Phase 2 Clinical Recruiting 1 160 Dr. Majid Ghafoori, Majid Ghafoori, Maryam Rameshrad, dr. seyed Kaveh Hojat 2020-08-27
Relation between HLA typing and ABO Blood group to infection by novel Wuhan Corona virus Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Christian Medical College, Vellore, India India 2020-08-25 12752, CTRI/2020/08/027194 Phase Not Applicable Not yet recruiting 1 80 Snehil Kumar 2020-08-27
Impact of COVID -19 situation on people staying and discharged from a psychiatric rehabilitation centre Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kasturba Medical College, Manipal India 2020-08-31 CTRI/2020/08/027193 Phase Not Applicable Not yet recruiting 1 54 Rajeshkrishna Bhandary P 2020-08-27
To assess the impact of COVID-19 pandemic on the delivery of radiation therapy in delhi national capital region, india Cancer, Coronavirus disease 19 infection Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Max Super Speciality Hospital India 2020-08-22 CTRI/2020/08/027192 Phase Not Applicable Not yet recruiting 3 500 Dr Rashi Agrawal 2020-08-27
Effect of ifiltration of dexamethasone as primary emergency management in patients with symptomatic apical periodontitis during Coronavirus Disease 2019 outbreak Coronavirus disease 19 infection, Pain dexamethasone plus ligocaine Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Pacific Dental College and hospital India 2020-08-24 CTRI/2020/08/027191 Phase 2 Clinical Not yet recruiting 1 42 Dr Afzal Ali 2020-08-27
Response time of motorlance in COVID-19 pandemic Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Khon Kaen University Thailand 2020-08-20 TCTR20200820006 Phase Not Applicable Recruiting 1 871 Korakot Apiratwarakul 2020-08-27
Role of chest CT scan in covid19 patients: A study in a dedicated covid hospital of odisha Coronavirus disease 19 infection Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) KIIT University India 2020-08-20 CTRI/2020/08/027189 Phase Not Applicable Not yet recruiting 1 1600 Sangram Panda 2020-08-27
The effect of Ayurvedic intervention (Ayurveda Raksha Kit) as a preventive measure in the Pandemic of COVID-19 - A community based study Coronavirus disease 19 infection Ayurvrda Raksha Kit alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Council for Research in Ayurvedic Sciences India 2020-08-28 CTRI/2020/08/027316 Phase 3 Clinical Not yet recruiting 20 Dr Alok Shrivastav, Dr Amin Hetalben, Dr Deepa Sharma, Dr Dipsunder Sahu, Dr EmySSurendram, Dr Gopesh Kumar, Dr Govind Reddy, Dr Jai Venkata Saiprasad, Dr K Anumol, Dr Kuldeep, Dr Laxman Bhurke, Dr PL Bharti, Dr Parvathy G Nair, Dr Rinky Thakur, Dr S Asha, Dr SK Vedi, Dr Seema jain, Dr Shriprakash, Dr Sunita mata, Dr Susmita P Otta, Dr Vineeta Kumari Negi 2020-08-27
Assessment of anxiety related to excessive internate search regarding covid-19 pandemic in medical students and para-medical staff Anxiety disorder, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Gujarat Cancer Society Medical college hospital and research centre India 2020-08-26 CTRI/2020/08/027301 Phase Not Applicable Not yet recruiting 1 200 Krishna Dave 2020-08-27
The effect of nebulizing peppermint extract and rose extract on percentage of blood oxygen saturation in patients with COVID-19 Coronavirus disease 19 infection peppermint extract (Barij Essence brand) alone, rose extract (Barij Essence brand) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Shahid Beheshti University of Medical Sciences Iran 2020-06-29 IR.SBMU.RETECH.REC.1399.353, IRCT20190131042569N5 Phase 3 Clinical Recruiting 1 60 Nima Saeedi, Seyed Ali Ziayi 2020-08-27
A Study to Evaluate the Safety and Immunogenicity of AdimrSC-2f Vaccine Coronavirus disease 19 infection AdimrSC-2f alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Adimmune Corp Taiwan 2020-08-20 2021-03-20 ADPCT20011X, NCT04522089 Phase 1 Clinical Recruiting 1 7 Months 70 Ellie Chen, Shan-Chwen Chang, Sung-Ching Pan, Szu-Min Hsieh, Wang-Da Liu 2020-08-27
TARGET-VIP: Prospective Hospital Registry of Patients With Suspected or Confirmed Coronavirus Infection (COVID-19) and Community-acquired Pneumonia Coronavirus disease 19 infection, Pneumonia, Viral pneumonia computerized tomography alone, polymerase chain reaction alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Research Center for Preventive Medicine Pirogov National Medical Surgical Center Russian Federation 2020-04-06 2022-05-01 02-07/20, NCT04522076, TARGET-VIP Phase Not Applicable No longer recruiting 2 24 Months 1124 Andrey Pulin, MD, PhD, Mikhail Loukianov, MD, PhD, Sergey Martsevich, MD, PhD 2020-08-25
The effect of progressive muscle relaxation on covid-19 anxiety in pregnant women Anxiety disorder, Coronavirus disease 19 infection Progressive muscle relaxation technique training alone, Routine prenatal care alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tehran University of Medical Sciences Iran 2020-08-07 IR.TUMS.MEDICINE.REC.1399.287, IRCT20200630047962N1 Phase Not Applicable Recruiting 1 126 Mohammadali Sahrayian, Mojgan Zendehdel 2020-08-25
TelePark: Efficacy and feasibility of Teleneurorehabilitation in Persons with Parkinsons Disease Coronavirus disease 19 infection, Parkinsons disease Tele-Neurorehabilitation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Lady Hardinge Medical College India 2020-09-01 CTRI/2020/08/027300, TelePark Phase Not Applicable Not yet recruiting 1 100 Rajinder K Dhamija 2020-08-27
A study to find out possible causes of mortality amongst the Covid-19 patients that are admitted in GCS Medical College, Ahmedabad Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gujarat Cancer Society Medical college hospital and research centre India 2020-08-31 CTRI/2020/08/027299 Phase Not Applicable Not yet recruiting 1 600 Dr Rushi Rashmikant Patel 2020-08-25
C3-RCT: Catalyzing the Containment of COVID-19 Coronavirus disease 19 infection, HIV infection nitazoxanide alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Cape Town Aurum Institute, National Institutes of Health, Perinatal HIV Research Unit, South African Medical Research Council, Texas Tech University, University Of Kwazulu-Natal South Africa 2020-08-19 2021-08-31 C3-RCT, C3-RCT, NCT04523090 Phase 2/Phase 3 Clinical Not yet recruiting 1 12 Months 960 Ali Esmail, MD, Keertan Dheda, Keertan Dheda, MD/PhD 2020-08-27
Effect of oral health care and mouth rinse in treatment of Covid-19 Coronavirus disease 19 infection Professional oral health care education alone, Variable regimens including betadine , chlorhexidine , povidone-iodine Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kashan University of Medical Sciences and Health Services Iran 2020-06-05 IR.KAUMS.REC.1399.015, IRCT20200527047581N1 Phase 2/Phase 3 Clinical No longer recruiting 2 200 Dr. Hamidreza Banafsheh, Dr.Mohammad Reza Sharif, Elaheh GhasemzadehHosseini, Soltan Ali Bahmani 2020-08-25
Effectiveness of Siddha Medicines Kabasura Kudineer and Nilavembu Kudineer in the Management of Smptomatic COVID 19 patients Coronavirus disease 19 infection Kaba sura Kudineer alone, Nilavembu Kuidneer  alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Central Council for Research in Siddha, Government Institute of Medical Sciences, Greater Noida India 2020-08-22 CTRI/2020/08/027286 Phase 2 Clinical Not yet recruiting 1 90 Dr ANURAG SRIVASTAVA, Dr R MANICKAVASAGM 2020-08-26
An Exploratory Study of ADR-001 in Patients With Severe Pneumonia Caused by SARS-CoV-2 Infection (COVID-19) Coronavirus disease 19 infection, Lung inflammation, Respiratory failure, Viral pneumonia ADR-001 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rohto Pharmaceutical Co Ltd Japan 2020-09-30 2021-12-31 ADR-001-1919, NCT04522986 Phase 1 Clinical Not yet recruiting 1 15 Months 6 Rohto Pharmaceutical Co., Ltd., Yuji Fujino, MD 2020-08-26
CLBS-119 for Repair of COVID-19 Induced Pulmonary Damage Coronavirus disease 19 infection, Lung injury, Respiratory distress syndrome, Respiratory failure, Viral pneumonia CLBS-119 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Caladrius Biosciences Inc US 2020-09-30 2021-05-31 CLBS119-P01, NCT04522817 Phase 1 Clinical Not yet recruiting 1 8 Months 12 Christine L Kotynski, Douglas W Losordo, MD 2020-08-27
Ethnic Differences in the Impact of Breast Cancer on Employment Status, Financial Situation, and Quality of Life Breast tumor, Coronavirus disease 19 infection survey web-based or telephone interview alone Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Memorial Sloan-Kettering Cancer Center City University of New York, NYC Health & Hospitals/ Lincoln Medical Center, New York City Health and Hospitals Corp, New York Presbyterian Queens, Queens Medical Associates, Ralph Lauren Center for Cancer Care and Prevention US 2010-05-31 2021-05-31 10-071, NCT01134172 Phase Not Applicable No longer recruiting 15 132 Months 935 Victoria Blinder, M.D., M.Sc. 2020-08-27
Metacognitive Therapy and Work Interventions for Patients on Sick Leave Due to Common Mental Disorders Anxiety disorder, Coronavirus disease 19 infection, Depression, Psychiatric disorder Metacognitive therapy alone, work-focused interventions alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Norwegian University of Science and Technology (NTNU) Diakonhjemmet Sykehus Norway 2017-10-31 2023-04-30 2015/1794, NCT03301922 Phase Not Applicable Recruiting 1 66 Months 240 Odin Hjemdal, phd prof, Odin Hjemdal, prof, Ragne GH Gjengedal 2020-08-27
PCCE: Primary Care Clinical Excellence Incentive Study Coronavirus disease 19 infection Leadership Training alone, Monthly email communication alone, Social comparison Intervention alone, Standard communication email alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of California Los Angeles US 2019-11-01 2021-07-01 12345, NCT04237883, PCCE Phase Not Applicable No longer recruiting 1 20 Months 225 Daniel M. Croymans 2020-08-24
A Transdiagnostic Course for Common Mental Health Problems in Primary Care Anxiety disorder, Coronavirus disease 19 infection, Depression Large-group transdiagnostic course alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Karolinska Institutet Sweden 2020-08-31 2021-12-31 2019-04816, NCT04522713 Phase Not Applicable Not yet recruiting 1 16 Months 68 Erland Axelsson, PhD 2020-08-24
A trial to evaluate Zofin for the treatment of patients with Coronavirus disease 19 infection Coronavirus disease 19 infection Zofin alone Organicell Regenerative Medicine Phase Not Applicable Status not specified 0 1 2020-08-24
TIP-OA: Telehealth Intervention Program for Older Adults Acute stress disorder, Coronavirus disease 19 infection, Psychiatric disorder Telehealth Intervention Program (TIP-OA) alone, semi-structured interviews alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Lady Davis Institute Canada 2020-08-31 2022-08-31 NCT04523610, TIP-OA, TIP-OA Phase Not Applicable Not yet recruiting 1 24 Months 258 Harmehr Sekhon, PHD, Soham Rej, MD/MSc 2020-08-27
Impact of COVID-19 on Mental Health of Patients With Skin Picking Coronavirus disease 19 infection, Psychiatric disorder Internet-based Cognitive Behavioral Therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital de Clinicas de Porto Alegre Federal University of Rio Grande do Sul Brazil 2020-08-11 2021-03-31 31520820.1.0000.5327, NCT04522492 Phase Not Applicable Recruiting 1 7 Months 20 Carolina Blaya Dreher, PhD 2020-08-27
Does Quality of Life Decline During the COVID-19 Pandemic and Can we Change Behaviour to Improve Poor Quality of Life? Coronavirus disease 19 infection extended intervention alone, online questionnaire alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Manchester UK 2020-05-22 2022-12-31 2020-9463-15184, NCT04522128 Phase Not Applicable Recruiting 1 31 Months 969 Christine Rowland, Tracy Epton 2020-08-27
NH-Shingrix: Training the Innate Immune System Against SARS-CoV-2 (COVID-19) Using the Shingrix Vaccine in Nursing Home Residents Coronavirus disease 19 infection, Influenza virus infection, Viral pneumonia GSK-1437173A alone Healthy volunteers accepted, Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Oklahoma Oklahoma Medical Research Foundation US 2020-09-30 2021-09-30 NCT04523246, NH-Shingrix, OUHSC IRB12394 Phase 0 Clinical Not yet recruiting 1 12 Months 250 Barbara Carlson, Barbara W. Carlson, RN, Ph.D., Diana L Sturdevant, RN, Ph.D. 2020-08-26
Providing Suboxone and PrEP Using Telemedicine Coronavirus disease 19 infection, HIV infection, Opiate dependence Pre-exposure prophylaxis alone, Telemedicine alone, buprenorphine hydrochloride (oral, formulated with abuse-deterrent naloxone), Indivior alone Opioid receptor kappa antagonist, Opioid receptor mu agonist Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Duke University US 2020-09-30 2021-05-31 NCT04521920, PRO00104147, PRO00104148 Phase 4 Clinical Not yet recruiting 3 8 Months 20 Hillary Chen, MPH, Hillary Murphy, MPH, Mehri McKellar, MD 2020-08-25
COCOVIH: COVID-19 and HIV Patients Coronavirus disease 19 infection, HIV infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre de Recherches et d'Etude sur la Pathologie Tropicale et le Sida France 2020-07-01 2022-06-30 COCOVIH, CREPATS 013, NCT04523012 Phase Not Applicable Recruiting 1 24 Months 2200 Valerie POURCHER, MD, Valérie Pourcher, MD, Yasmine Dudoit, valérie Pourcher, MD 2020-08-25
CODYS: Measurement of the Efficacy of Morphine in the Early Management of Dyspnea in COVID-19 Positive Patients Coronavirus disease 19 infection, Dyspnea, Respiratory disease, Respiratory distress syndrome morphine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospices Civils De Lyon France 2020-06-01 2021-02-28 CODYS, CODYS_2020, NCT04522037 Phase Not Applicable Recruiting 3 9 Months 200 Guillaume Economos, Dr, Myriam Legenne, Myriam Legenne, Dr, Sophie Francioni, Dr 2020-08-27
RECOVER: Rehabilitation After Admission in Intensive Care Unit for COVID-19 Coronavirus disease 19 infection Centre Hospitalier Régional Metz-Thionville France 2020-04-01 2021-05-01 2020-05OBS-CHRMT, NCT04523051, RECOVER Phase Not Applicable Recruiting 3 13 Months 40 Armelle Stephan-Carlier, MD, Catherine Achour, MD, Clémence Deffinis, MD, Elise Schwartz-Leduc, MD, Margaux Temperelli, MD, Nadia Ouamara, Rémi Leclaire, MD, Vincent Dinot 2020-08-26
COVID19-CED-PÄD: Online survey on clinical care, health problems and str stress during the corona pandemic in children and adolescents with chronic inflammatory bowel disease (IBD) Acute stress disorder, Coronavirus disease 19 infection, Inflammatory bowel disease online questionnaire alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Technical University of Munich Klinikum Grosshadern Der Ludwig-Maximilians-Universitat Germany 2020-08-25 20-690 KB and 20-642, COVID19-CED-PÄD, DRKS00022500 Phase Not Applicable Not yet recruiting 1 500 Elisabeth Klucker, Leandra Koletzko, Sibylle Koletzko, Thu Giang Le Thi, Tobias Schwerd 2020-08-27
Photobiomodulation anti-inflammatory effect in COVID-19 Coronavirus disease 19 infection, Viral pneumonia Neolys (Life+) alone, photobiomodulation alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shaheed Beheshti Medical University Iran 2020-06-30 IR.SBMU.NRITLD.REC.1399.131, IRCT20200616047799N1 Phase 1/Phase 2 Clinical No longer recruiting 1 40 Alireza Eslaminejad, Mehran Marashian, Research department 2020-08-25
A randomized, double-blinded, placebo-controlled phase I/II clinical trial of Zofin against COVID-19 Coronavirus disease 19 infection Zofin alone Organicell Regenerative Medicine Alternative Research Associates, LLC, Larkin Community Hospital US Phase 1/Phase 2 Clinical Planned 1 20 2020-08-24
An observational study to assess the relation between previous treatment with ACE inhibitors, angiotensin-receptor blockers, beta-blockers, calcium-channel blockers, or thiazide diuretics and the likelihood of a positive or negative result on Covid-19 testing as well as the likelihood of severe illness (defined as intensive care, mechanical ventilation, or death) among patients who tested positive Coronavirus disease 19 infection ACE inhibitors (cardiovascular diseases), Jiangsu Kanion Pharmaceutical Co Ltd/China Pharmaceutical University alone, angiotensin receptor blockers (prodrug, cardiovascular diseases), KemPharm alone, beta blockers (glaucoma), University of Nottingham alone, calcium-channel blockers alone, thiazide diuretics alone ACE inhibitor, Angiotensin receptor antagonist, Beta 1 adrenoceptor antagonist National Center For Advancing Translational Sciences, National Institutes of Health, US Department of Health and Human Services Phase Not Applicable Status not specified 0 12594 2020-08-26
Evaluation of the effect of SINA anti-flu natural product on COVID-19 Coronavirus disease 19 infection, Respiratory disease Variable regimens including SINA anti-flu medicinal natural product , azithromycin , naproxen Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bagheiat-allah University of Medical Sciences Iran 2020-09-22 IR.BMSU.REC.1399.038, IRCT20160131026298N5 Phase 2/Phase 3 Clinical Not yet recruiting 1 80 AHMAD REZA SHARIFI OLOUNABADI, Ahmad Reza Sharifi Olounabadi, Gholamhosein Alishiri, mortezaazadi 2020-08-25
A clinical trial of ELI-004 for the prevention of Coronavirus disease 19 infection Coronavirus disease 19 infection ELI-004 alone TLR-9 agonist Elicio Therapeutics Phase Not Applicable Planned 0 2020-08-24
Evaluation of the effect of oral ivermectin on patients with COVID-19 Coronavirus disease 19 infection Variable regimens including azithromycin , hydroxychloroquine sulfate , ivermectin Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Tehran University of Medical Sciences Iran 2020-04-19 IR.TUMS.MEDICINE.REC.1399.031, IRCT20180922041089N4 Phase 3 Clinical No longer recruiting 3 130 Abolfazl Zendedel, Abolfazl Zendehdel, Mohammadali Sahraeeian, Saeedreza Jamali moghadam 2020-08-26
Global Phase III Trial of A COVID-19 Vaccine in Adults 18 Years of Age and Older Coronavirus disease 19 infection Ad5-nCoV alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) CanSino Biologics Inc Institute of Biotechnology the Academy of Military Medical Sciences PLA Pakistan 2020-08-30 2022-01-30 CS-CTP-AD5NCOV-III, NCT04526990 Phase 3 Clinical Not yet recruiting 1 17 Months 40000 Aamer Ikram SI, phD, Fengcai Zhu, Jinbo Gou, MD, Joanne M angley, MD, Scott A Halperin, MD 2020-08-27
BTL-TML-COVID: A Study in Adults to Test the Effects of Low Dose Thimerosal on Symptoms of COVID-19 Coronavirus disease 19 infection BTL-TML-COVID alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Beech Tree Labs Inc Norwich Clinical Research Associates Ltd, The Curavita Corp US 2020-07-30 2020-10-30 2020-04-0311, BTL-TML-COVID, NCT04522830 Phase 2 Clinical Recruiting 1 3 Months 40 DeAnn Sims, Duane Harris, MD, Lee Truax-Bellows 2020-08-26
A Phase II, Randomized, Double-blind, Placebo-controlled, Proof-of-Concept Study to Evaluate the Safety and Efficacy of Antroquinonol in Hospitalized Patients With Mild to Moderate Pneumonia Due to COVID-19 Coronavirus disease 19 infection, Viral pneumonia antroquinonol alone MEK-1 protein kinase inhibitor, Ras gene inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Golden Biotechnology Corp 2020-09-07 2021-03-31 GHCOVID-2-001, NCT04523181 Phase 2 Clinical Not yet recruiting 0 6 Months 174 2020-08-26
A case-series of Herpes zoster infections in COVID‐19‐positive patients Coronavirus disease 19 infection, Varicella zoster virus infection hydroxychloroquine alone, mechanical ventilation alone, tocilizumab alone Universita di Bologna Phase Not Applicable Status not specified 0 4 2020-08-25
A clinical study based on novel Coronavirus intelligent robot for nasopharyngeal swab sampling Coronavirus disease 19 infection nasopharyngeal swab sampling alone, novel Coronavirus intelligent robot alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shuguang Hospital Shanghai University Of Traditional Chinese Medicine 2020-10-01 2022-09-30 ChiCTR2000035985 Phase 0 Clinical Not yet recruiting 0 24 Months Bin Shen 2020-08-26
PAMOCOS: Proadrenomedullin Assessment of Multi-Organ Failure in Covid-19 Sepsis Coronavirus disease 19 infection, Multiple organ failure, Sepsis, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier De Lens France 2020-05-20 2020-10-07 2020-05, NCT04522310, PAMOCOS Phase Not Applicable Recruiting 8 4 Months 183 CLAIRE BOULLE, Dr, CLEMENT DELPIERRE, Dr, DELPHINE COLLING, Dr, FABIEN LAMBIOTTE, Dr, GUILLAUME BRUNIN, Dr, KATHY DERNIVOIX, MELANIE VERLAY, Mélanie VERLAY, Nicolas VAN GRUNDERBEECK, Dr, SEBASTIEN BEAGUE, Dr, THOMAS CAULIER, Dr 2020-08-26
Multi-center study on intelligent accurate diagnosis and critical illness prediction of novel coronavirus pneumonia (COVID-19) with multimodal imaging Coronavirus disease 19 infection, Pneumonia Etiological examination alone, multimodal imaging alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shanghai Public Health Clinical Center Shanghai shen-kang hospital clinical development center China 2020-10-01 2023-11-01 ChiCTR2000036217 Phase 0 Clinical Not yet recruiting 4 37 Months 4000 Yuxin Shi 2020-08-27
Study of host genome variants in association to the varying severity of COVID-19 symptoms in Sabah patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universiti Malaysia Sabah Malaysia 2020-09-01 2022-09-22 55933, NMRR-20-1785-55933 Phase Not Applicable Not yet recruiting 1 24 Months Dr Lee Heng Gee, Professor Dr. Lee Ping Chin 2020-08-27
The Efficacy of Early Prone or Lateral Positioning in Severe COVID-19 Patients: a Single-Center, Prospective, Cohort Study Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) West China Hospital China 2020-01-31 2020-02-15 ChiCTR2000035907 Phase 0 Clinical No longer recruiting 1 197 Liu Dan, Ni Zhong 2020-08-26
Evaluation of the course of COVID-19 and perceptions among those tested positive – a survey based study Coronavirus disease 19 infection survey alone University of Heidelberg Gesundheitsamt Rhein-Neckar Germany 2020-03-22 DRKS00022926, S-179/2020 Phase Not Applicable Suspended 1 1000 Claudia Denkinger 2020-08-27
AVID-CC: Adalimumab for coronavirus in community care Coronavirus disease 19 infection, Respiratory failure Standard care alone, adalimumab biosimilar, Sandoz alone TNF alpha ligand inhibitor, TNF binding agent Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Oxford Wellcome Trust UK 2020-07-01 2021-12-31 2020-003628-18, AVID-CC, IRAS 287434, ISRCTN33260034 Phase 2 Clinical Not yet recruiting 2 18 Months 750 Prof Richards 2020-08-26
A retrospective study to evaluate systematic assessment of venous thromboembolism (VTE) using complete duplex ultrasound (CDU) in anticoagulated COVID-19 patients Coronavirus disease 19 infection Complete duplex ultrasound alone, prophylactic anticoagulation therapy alone, therapeutic anticoagulation therapy alone Cochin Institute France Phase Not Applicable Status not specified 1 26 2020-08-24
A prospective, observational study to characterize the coagulation profile of COVID-19 ARDS patients with standard and viscoelastic coagulation tests and to evaluate their changes after establishment of an aggressive thromboprophylaxis Coronavirus disease 19 infection, Respiratory distress syndrome clopidogrel alone, coagulation profiling alone, heparin alone, thromboprophylaxis alone P2Y12 purinoceptor antagonist IRCCS Policlinico San Donato Phase Not Applicable Status not specified 0 16 2020-08-24
A case-series study to evaluate the efficacy of tissue plasminogen activator (tPA) treatment for COVID-19 associated acute respiratory distress syndrome (ARDS) Coronavirus disease 19 infection, Respiratory distress syndrome alteplase alone Tissue plasminogen activator stimulator Beth Israel Deaconess Medical Center, Harvard University, University of Colorado System Phase Not Applicable Status not specified 0 3 2020-08-24
Epidemiological Analysis of Ambulant Patients in a COVID-19 Outpatient Clinic Coronavirus disease 19 infection Wissenschaftliches Institut Bethanien e.V. Germany 2020-07-02 2020-12-31 NCT04521088, WI-1252 Phase Not Applicable Recruiting 1 5 Months 1000 Prof. Randerath, Prof. Dr, Simon Herkenrath 2020-08-26
AT-301 Nasal Spray in Healthy Adults Coronavirus disease 19 infection AT-301 (nasal spray, COVID-19), Atossa Therapeutics alone COVID19 Spike glycoprotein inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Atossa Therapeutics Inc, Avance Clinical Pty Ltd Australia 2020-08-07 2020-12-01 ACTRN12620000816954, AT-301-AU-01, NCT04519788 Phase 1 Clinical Recruiting 1 3 Months 50 Ben Canny, Dr Heather Fraser, Emir Redzepagic, MD, Jane Kelly, Meridee Arthur 2020-08-27
Impact of the COVID-19 pandemic and the political measures to contain its spread on children with disabilities and chronic illnesses and their families Coronavirus disease 19 infection Healthy volunteers accepted, Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Universitätsklinik Freiburg Klinik für Allgemeine Kinder und Jugendmedizin Klinik für Neuropädiatrie und Muskelerkrankungen Germany 2020-09-01 377/20, DRKS00022868 Phase Not Applicable Not yet recruiting 1 800 Thorsten Langer 2020-08-25
A phase I clinical trial of Ad26.COV2.S for potential treatment of COVID-19 infection Coronavirus disease 19 infection JNJ-78436735 alone Johnson & Johnson Brazil Phase 1 Clinical Planned 1 6000 2020-08-21
A clinical trial of urokinase plasminogen activator receptor targeted radio-immuno-therapeutics (uPRITs) for the potential treatment of patients with severe COVID-19 Coronavirus disease 19 infection urokinase plasminogen activator receptor targeted radio-immuno-therapeutics (uPRITs) alone Monopar Therapeutics LLC, Northstar Medical Radioisotopes Llc Aragen Bioscience Inc Phase Not Applicable Planned 0 2020-08-24
CARR-COV-02: Efficacy of a Nasal Spray Containing Iota-Carrageenan in the Prophylaxis of COVID-19 Disease in Health Personnel Dedicated to Patients Care With COVID-19 Disease Coronavirus disease 19 infection Iota-Carrageenan alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centro de Educación Medica e Investigaciones Clínicas Norberto Quirno Argentina 2020-07-24 2020-11-30 CARR-COV-02, CEMIC, NCT04521322 Phase 4 Clinical Recruiting 1 4 Months 400 Ariel Dogliotti, Juan Figueroa, MD, Mónica Lombardo, MD, Ricardo Valentini, MD, Ricardo c Valentini 2020-08-25
No-SARS: Antibodies Responses to COVID-19 Infection in Hospitalized Patients Coronavirus disease 19 infection ELISA alone, Luciferase assay alone, Luminometer alone, PV microneutralization assay alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Dammam Dammam Medical Complex, Institute for Research and medical consultation Saudi Arabia 2020-08-31 2021-02-28 ICU-06072020, NCT04520880, No-SARS Phase Not Applicable Not yet recruiting 1 6 Months 158 Amani MM Alnimr, MD, Fatimah A Al-Mishkab, MD, Hisham A Almuzayyen, MD, Iman Almansour, Ph.D., Iman Almansour, PhD, Jawaher Almusairii, MD, Laila P Asonto, MD, Moaz S Alammar, MD, Mohamed R El Tahan, MD, Mohammed Alnabi, MD, Mohammed S Alshahrani, MD, Mohammed SS Alshahrani, MD, Talal A Albrahim, MD, Yousef Al Mubarak, MD 2020-08-24
Staff Absenteeism and Delivery of Healthcare Services During the COVID-19 Pandemic Coronavirus disease 19 infection Poznan University of Medical Sciences Poland 2020-01-01 2020-04-30 3/2020/REH, NCT04521010 Phase Not Applicable Completed 1 4 Months 700 Ewa Chlebuś, MD 2020-08-21
MWLAHCW-COV: Mental workload assessment among healthcare worker among healthcare worker during pandemic COVID-19 at hospital Tunku Azizah (hospital kuala lumpur) Coronavirus disease 19 infection Hospital Tunku Azizah Malaysia 2020-08-30 2020-12-31 54627, MWLAHCW-COV, NMRR-20-1769-54627 Phase Not Applicable Not yet recruiting 1 4 Months Mr. MOHD ' AIZAT BIN MOHD BASARI 2020-08-25
The effect of herbal tea on improving respiratory symptoms in patients with Covid-19 Coronavirus disease 19 infection, Respiratory disorder herbal tea alone, routine treatment alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Isfahan University of medical Sciences Iran 2020-09-22 IR.MUI.MED.REC.1399.359, IRCT20200806048318N1 Phase 3 Clinical Not yet recruiting 1 80 Mehdi Akhve, Mehdi Akhveh, Shaghayegh Haghjoo Javanmard 2020-08-26
Characteristics in Post COVID-19 Patients Coronavirus disease 19 infection aerobic exercises alone, anaerobic exercises alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidade Metodista de Piracicaba Brazil 2020-08-11 2021-12-31 F110820, NCT04514705 Phase Not Applicable Recruiting 1 16 Months 20 Luiz F Falcão, PhD, Rodrigo S Rocha, Phd, Rodrigo Santiago Barbosa Rocha 2020-08-24
PRONE: Prone Position and Respiratory Outcomes in Non-Intubated COVID Patients Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia prone positioning alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Johns Hopkins University Duke University, Nox Medical, Smith & Nephew Inc, University of Miami, University of North Carolina, University of Pittsburgh 2020-09-01 2021-12-31 IRB00249663, NCT04517123, PRONE Phase Not Applicable Not yet recruiting 0 16 Months 100 Mahendra Damarla, Naresh Punjabi, MD 2020-08-24
A clinical trial of autologous stromal vascular fraction for the treatment of severe respiratory distress due to COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome autologous stromal vascular fraction alone GID BIO Richard King Mellon Foundation Phase Not Applicable Planned 0 2020-08-21
FERMIN: Fenofibrate Intervention as COVID-19 Therapy Coronavirus disease 19 infection fenofibrate (micronized), Fournier/Abbott alone, usual care alone Lipoprotein lipase stimulator, PPAR alpha agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Pennsylvania University of Arizona US 2020-08-18 2021-08-31 843729, FERMIN, NCT04517396 Phase 3 Clinical Recruiting 1 12 Months 300 Julio A. Chirinos 2020-08-24
The Investigation Into Beneficial Effects of High-dose Interferon Beta 1-a, Compared to Low-dose Interferon Beta 1-a in Moderate to Severe COVID-19 Coronavirus disease 19 infection interferon beta-1a follow-on biologic (subcutaneous), CinnaGen plus lopinavir + ritonavir HIV protease inhibitor, Interferon beta ligand Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shaheed Beheshti Medical University Iran 2020-08-20 2020-09-11 INTERFERON IN COVID, NCT04521400 Phase 2 Clinical Not yet recruiting 1 100 Behnam Rahimi, M.D, Firouze Hatami, M.D, Ilad Alavi Darazam, Ilad Alavi Darazam, M.D, Ilad Alavi Darazam, MD, Minoosh Shabani, M.D, Mohammad Mahdi Rabiei, M.D, Mohammad Reza Hajesmaeili, M.D, Omid Moradi, Seyed Sina Naghibi Irvani, M.D, Shervin Shokouhi, M.D 2020-08-24
Enhancement: Home-based Kidney Care in Native Americans of New Mexico (HBKC) Coronavirus disease 19 infection, Diabetes mellitus, End stage renal disease home-based kidney care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Native American Ancestry University of New Mexico Albuquerque area indian health board US 2020-09-01 2021-09-30 16-344-ENHANCEMENT, Enhancement, NCT04520191 Phase Not Applicable Not yet recruiting 1 13 Months 529 Vallabh O Shah, Vallabh Shah, PhD 2020-08-25
A Phase III clinical trial of Cannabis sativa for the treatment of COVID-19 and other infectious diseases Coronavirus disease 19 infection Cannabis sativa alone Asia Green Biotechnology Corp, Pathway Rx Inc Phase 3 Clinical Planned 0 15 2020-08-21
A Phase II clinical trial of Cannabis sativa for the treatment of COVID-19 and other infectious diseases Coronavirus disease 19 infection Cannabis sativa alone Asia Green Biotechnology Corp, Pathway Rx Inc 2021-01-31 Phase 2 Clinical Planned 0 300 2020-08-21
A clinical trial of replicating vesicular stomatitis virus vector-based vaccine (COVID-19), Israel Institute for Biological Research/Weizmann Institute of Science for the prevention of Covid-19 Coronavirus disease 19 infection VSV vector-based vaccine targeting spike glycoprotein (COVID-19), IIBR/Weizmann Institute of Science alone COVID19 Spike glycoprotein modulator Israel Institute for Biological Research Ministry of Health, Israel Israel 2020-10-31 Phase Not Applicable Planned 1 2020-08-26
SARS-CoV-2 Antibodies Based IVIG Therapy for COVID-19 Patients Coronavirus disease 19 infection airway support therapy alone, anti-COVID-19 intravenous immunoglobulin alone, anti-pyretic therapy alone, anti-viral medication therapy alone, antibiotic treatment alone, fluid resuscitation alone, hemodynamic support treatment alone, painkiller treatment alone, steroid therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dow University of Health Sciences Higher Education Commission of Pakistan Pakistan 2020-06-19 2021-03-31 BIOTECH001, NCT04521309 Phase 1/Phase 2 Clinical Recruiting 1 9 Months 50 Dr. Mohsin Bajwa, FCPS, Dr. Muneeba Sayeed, FCPS, Dr. Shaukat Ali, PhD, Dr. Sheikh Muhammad Khan, MBBS, Dr. Shobha Luxmi, FCPS, Dr.Shaukat Ali, PhD, Mr. Abdul Samad Khan, M.Phil, Mr. Elisha Shalim, BS, Mr. Mir Rashid Ali, M.Sc, Mr. Mujtaba Khan, BS, Mr. Syed Muneeb Uddin, M.Sc, Ms. Ayesha Ali, M.Sc, Ms. Fatima Anjum, M.Sc, Prof. Dr. Mohammed Saeed Quraishy, FRCS, Prof. Dr. Mohammed Saeed Quraishy, FRCS, FCPS, Shaukat Ali, PhD, Shobha Luxmi, FCPS 2020-08-24
A clinical trial of COVID-19 vaccine (inactivated, Vero cells/intramuscular), Wuhan Institute of Biological Products/Wuhan Institute of Virology, CAS for the treatment of Covid-19 Coronavirus disease 19 infection COVID-19 vaccine (inactivated, Vero cells/intramuscular), Wuhan Institute of Biological Products/Wuhan Institute of Virology, CAS alone Sinopharm China National Biotech Institute Co Ltd, Thomson Reuters Corp Peru, Morocco Phase 3 Clinical Recruiting 2 2020-08-21
A placebo-controlled, randomized, double-blind, phase I clinical study to assess BT-20 in the treatment of patients with COVID-19 infection Coronavirus disease 19 infection, Respiratory distress syndrome BT-20, Bone Therapeutics alone, standard supportive treatment alone Bone Therapeutics SA Belgium Phase 1 Clinical Planned 1 2020-08-26
ReMiCov: Retinal Microangiopathy in Patients after Covid-19 Disease Coronavirus disease 19 infection, Microangiopathy optical coherence tomography angiography alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hannover Medical School Germany 2020-07-13 9159_BO_K_2020, DRKS00022874, ReMiCov Phase Not Applicable Recruiting 1 66 Jan Tode 2020-08-25
A phase I trial of COVID-19 vaccine(vaxipatch technology)for the potential treatment of COVID-19 Coronavirus disease 19 infection COVID-19 vaccine (vaxipatch technology, COVID-19 infection) Verndari/University of California Davis alone COVID19 Spike glycoprotein modulator Verndari Inc Phase 1 Clinical Planned 0 2020-08-21
Efficacy and Safety of DWJ-1248 in Patients With Mild to Moderate COVID-19 Compared to the Placebo Coronavirus disease 19 infection DWJ-1248 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Daewoong Pharmaceutical Co Ltd 2020-08-31 2020-12-31 DW_DWJ1248201, NCT04521296 Phase 2 Clinical Not yet recruiting 0 4 Months 90 2020-08-24
CPCP: Convalescent Plasma for COVID-19 Patients Coronavirus disease 19 infection convalescent plasma alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Vinmec Research Institute of Stem Cell and Gene Technology National Hospital Of Tropical Diseases, National Institute of Hematology and Blood Transfusion, Vietnam, National Institute of Hygiene and Epidemiology, Vietnam Vietnam 2020-12-01 2021-10-30 CPCP, ISC.20.11.2, NCT04521036 Phase 1/Phase 2 Clinical Not yet recruiting 1 10 Months 44 Liem Thanh Nguyen, PhD, Phuong Hoang Nguyen, MPH 2020-08-24
A single-center, retrospective and observational study to assess famotidine in the treatment of patients with severe COVID-19 Coronavirus disease 19 infection famotidine alone Histamine H2 receptor antagonist Hartford Hospital US Phase Not Applicable Status not specified 1 83 2020-08-21
iGenes-COVID19: Investigating the Involvement of ACE and Angiotensinogen Genes' Polymorphism Along With Other Thrombophilic Genotypes in Severe Forms of COVID-19 With/Without Thrombotic Events Arterial thrombosis, Coronavirus disease 19 infection, Cough, Deep vein thrombosis, Fever, Lung embolism, Myalgia, Myocardial infarction, Phlebothrombosis, Stroke multiplex PCR alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Grigore T. Popa University of Medicine and Pharmacy Romania 2020-08-18 2021-08-18 GTP0051, NCT04519398, iGenes-COVID19 Phase Not Applicable Recruiting 1 12 Months 60 Adrian Covic, Professor, Alexandru Burlacu, Lecturer, Alexandru Burlacu, MD, PhD, Iolanda Popa, MD, PhD, Radu Crisan-Dabija, Lecturer, Radu Crisan-Dabija, MD, PhD 2020-08-25
The effect of selenium, vitamin C and methylprednisolone combination on mortality and morbidity of COVID-19 patients Coronavirus disease 19 infection, Respiratory distress syndrome Variable regimens including hydroxychloroquine , lopinavir + ritonavir , methylprednisolone , selenium , vitamin C HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tabriz University of Medical Sciences Iran 2020-06-29 IR.TBZMED.REC.1399.340, IRCT20190312043030N2 Phase 3 Clinical Recruiting 1 40 Dr Abolghasem Joyban, Dr.Seied Hadi Saghaleini 2020-08-25
SPP – SmartPointer Pilot study: Pilot study to investigate the SmartPointer system in the context of domestic life with older people in need of support Aging, Coronavirus disease 19 infection SmartPointer (SP) system alone Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Charite Universitaetsmedizin Berlin Bundesministerium fur Bildung und Forschung Germany 2020-12-01 DRKS00022533, EA1/137/20, SPP – SmartPointer Pilot study, U1111-1256-0263 Phase Not Applicable Not yet recruiting 1 117 Susan Vorwerg 2020-08-21
Transpulmonary Pressure Measurements in Intubated Children With Covid-19 Respiratory Failure Coronavirus disease 19 infection, Respiratory failure transpulmonary pressure measurement alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) Mayo Clinic, Minnesota US 2020-05-21 2021-01-31 20-003743, NCT04519411 Phase Not Applicable Recruiting 1 8 Months 10 Stephen Gleich, M.D., Stephen J Gleich, MD 2020-08-25
MFMU COVID-19: Maternal Morbidity and Mortality During the COVID-19 Pandemic Coronavirus disease 19 infection, Pregnancy disorder Female The George Washington University Biostatistics Center Eunice Kennedy Shriver National Institute of Child Health & Human Development US 2020-06-23 2021-12-31 HD36801 - MFMU COVID-19, MFMU COVID-19, NCT04519502, U01HD036801 Phase Not Applicable Recruiting 12 18 Months 26400 Alan T. Tita, MD, Amber Sowles, RN BSN CORP, Andrew Bremer, MD, PhD, MAS, Anna Bartholomew, RN,BSN,CCRP, Ashley Salazar, MSN, Cora MacPherson, PhD, Cynthia Gyamfi-Bannerman, MD, Donna Allard, RN, Dwight J Rouse, MD, Felecia Ortiz, RN,BSN,CCRC, Gail Mallett, RN,BSN, CCRC, George R Saade, MD, Hyagriv Simhan, MD, MS, Janatha Grant, BSN, Jennifer Bailit, MD, Jennifer Craig, BSN, John M. Thorp Jr., MD, Kelly Clark, RN BSN, Maged Costantine, MD, Melissa Bickus, BS, RN, Rebecca Clifton, PhD, Sabine Bousleiman, RNC MSN, Samuel Parry, MD, Suneet Chauhan, MD, Torri Metz, MD, Wendy Dalton, RNC, William Grobman, MD 2020-08-24
SARS-CoV-2 Admission Screening in a University Hospital Setting Coronavirus disease 19 infection nasopharyngeal sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Basel Switzerland 2020-04-01 2021-03-31 2020-00808, NCT04519372 Phase Not Applicable No longer recruiting 1 12 Months 4099 Sarah Tschudin-Sutter, Prof. Dr. MD 2020-08-20
DALIA: Evaluation of the effect and the safety of the CIGB-258 peptide in the treatment of severe or critical patients due to COVID-19 Coronavirus disease 19 infection CIGB-258 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Center for Genetic Engineering and Biotechnology, Consejo Nacional de Ciencia y Tecnología, Mexican Health Research Coordination Mexico 2020-08-11 DALIA, IG/CIGB-258I/CV/2001, RPCEC00000330 Phase 2 Clinical Not yet recruiting 1 60 Francisco Hernandez Bernal, Juan Anda Garay 2020-08-21
A clinical trial of AV-001 for the treatment of COVID-19-associated acute lung injury and acute respiratory distress syndrome (ARDS) Acute lung injury, Coronavirus disease 19 infection, Respiratory distress syndrome AV-001, Vasomume Therapeutics alone Tek tyrosine kinase receptor stimulator Vasomune Therapeutics Inc Phase Not Applicable Planned 0 2020-08-26
Determination of the Hemoadsorption Impact as Adjunctive Treatment Upon the Support Therapy of COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome CytoSorb alone, continuous renal replacement therapy alone, fluid challenge alone, inotropic support alone, mechanical ventilation alone, vasopressor therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Brugmann University Hospital Belgium 2020-05-03 2020-12-01 BRUGMANNUH 1066, NCT04518969 Phase Not Applicable Recruiting 1 6 Months 24 Dr David DE BELS, Patrick Honore, MD, Patrick Honoré, MD 2020-08-20
A clinical trial of AK-119 for the treatment of COVID-19 patients Coronavirus disease 19 infection AK-119 alone CD73 antagonist Akeso Biopharma Inc New Zealand Phase Not Applicable Planned 1 2020-08-20
External pilot study to evaluate the feasibility of the development of a pragmatic clinical trial to determine the clinical utility of the repositioning of Pentoxifylline as an immunomodulator and regulator of the Renin Angiotensin system in the treatment of COVID-19 Coronavirus disease 19 infection pentoxifylline alone Phosphoric diester hydrolase inhibitor IMSS General Hospital of Zone 2A "Troncoso" Mexico 2020-785-079 Phase 4 Clinical Status not specified 1 50 2020-08-24
Epidemiological survey of COVID-19 patients in Japan Coronavirus disease 19 infection Hiroshima University Japan 2020-05-12 UMIN000041450 Phase Not Applicable Recruiting 1 10000 Nobuaki Shime, Shinichiro Ohshimo 2020-08-24
COVID-19 in Lahad Datu Coronavirus disease 19 infection, Viral pneumonia Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) HOSPITAL LAHAD DATU Malaysia 2020-08-16 2020-12-15 55950, NMRR-20-1756-55950 Phase Not Applicable Status not specified 1 4 Months 54 Dr CHEO SENG WEE 2020-08-21
MKK-COVID-19: Health Awareness Model and COVID-19 Outbreak Containment Behavior Among Sri Petaling Mosque Clusters Coronavirus disease 19 infection Institute for Health Behavioural Research (IHBR) Malaysia 2020-08-31 2021-01-31 55269, MKK-COVID-19, NMRR-20-1760-55269 Phase Not Applicable Status not specified 2 5 Months Mr Abu Bakar Bin Rahman 2020-08-21
Vitamin D Status and Immune-inflammatory Status in Different UK Populations With COVID-19 Infection Coronavirus disease 19 infection Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Guy's & St Thomas' Hospital NHS Trust UK 2020-09-01 2020-12-31 285176, NCT04519034 Phase Not Applicable Not yet recruiting 1 4 Months 27000 Agata Sobczynska-Malefora, PhD, Rachel Fay, Ms 2020-08-21
A study to assess risk of mortality and  current health characteristics of Covid-19 patients Coronavirus disease 19 infection LifeBridge Health, PeraHealth, Sinai Hospital of Baltimore, Yale New Haven Health US Phase Not Applicable Status not specified 2 2020-08-20
TRACE: Transmission of Covid-19 in Crowded Environments Coronavirus disease 19 infection STOPCOV alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Desmond Tutu HIV Foundation European and Developing Countries Clinical Trials Partnership, University of Cape Town South Africa 2020-08-03 PACTR202008485004797, TRACE Phase Not Applicable Not yet recruiting 7 720 Catherine Orrell, Lara Fairall, LindaGail Bekker, Philip Smith 2020-08-20
COV-RECUP: Medium and Long Term Follow-up of COVID-19 Infected Patients: Research and Characterization of Pulmonary Sequelae Coronavirus disease 19 infection, Viral pneumonia CT Scan alone, Pulmonary function testing alone, Ventilatory polygraphy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University Hospital of Besancon France 2020-05-18 2025-08-18 2020/499, COV-RECUP, NCT04519320 Phase Not Applicable Recruiting 1 63 Months 140 Eberst Guillaume, PH, Guillaume Eberst, PH, Lucie Laurent, PhD 2020-08-25
A follow-up study to evaluate Lucid Robotic System to generate additional findings on the pathophysiology of COVID-19 Coronavirus disease 19 infection Lucid Robotic System alone NovaSignal Corp Phase Not Applicable Status not specified 0 2020-08-20
A study to evaluate Lucid robotic system to remotely assess and monitor critically ill patients with COVID-19 Coronavirus disease 19 infection, Viral pneumonia Lucid robotic system alone NovaSignal Corp Phase Not Applicable Status not specified 0 18 2020-08-20
Evaluation of Newborns Presenting With Suspected COVID-19 Coronavirus disease 19 infection, Respiratory disease Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dr. Behcet Uz Children's Hospital Turkey 2020-03-01 2020-08-31 2020/251, NCT04519307 Phase Not Applicable No longer recruiting 1 6 Months 72 Senem Alkan Özdemir 2020-08-23
Daily Regimen of Tenofovir/Emtricitabine as Prevention for COVID-19 in Health Care Personnel in Colombia Coronavirus disease 19 infection personal protective equipment (PPE) alone, tenofovir disoproxil fumarate + emtricitabine (fixed dose), Gilead Sciences alone HIV-1 reverse transcriptase inhibitor, Nucleoside reverse transcriptase inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hospital Universitario San Ignacio Colombia National University Hospital, Fundación Universitaria Autónoma de Las Américas, Hospital Universitario San Jorge de Pereira, Hospital de la Samaritana, Sede Bogotá y Sede Zipaquirá, Javeriana University, Universidad Tecnológica de Pereira Colombia 2020-08-30 2021-04-01 2020 /143, 77389, NCT04519125 Phase 2/Phase 3 Clinical Not yet recruiting 1 7 Months 950 Juliana Maria Cuervo Rojas, MD. MSc. PhD., Sandra Liliana Valderrama, MD, Sandra Valderrama- Beltrán, MD. Msc. 2020-08-23
Adapt Out COVID: A Study for Outpatients With COVID-19 Coronavirus disease 19 infection LY-CoV555 alone COVID19 Spike glycoprotein modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Allergy and Infectious Diseases AIDS Clinical Trials Group, Eli Lilly & Co US 2020-08-19 2021-02-28 38742, A5401/ACTIV-2, Adapt Out COVID, NCT04518410 Phase 2/Phase 3 Clinical Recruiting 5 6 Months 2000 Becky Straub, Chris Jonsson, David Smith, MD, MAS, Jay Dwyer, Lisa Kessels, Samantha Fortier 2020-08-27
Telemedical Risk Assessment and Preoperative Evaluation (TAPE) Anesthesia, Coronavirus disease 19 infection TAPE Software alone, Telemedicine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Docs in Clouds Telecare GmbH, Rheinisch-Westfaelische Technische Hochschule Aachen Germany 2020-04-20 2020-11-30 19-174, NCT04518514 Phase Not Applicable Recruiting 1 7 Months 100 Andreas Follmann, Dr., Jan Wienhold, cand. med. 2020-08-22
FLOWER: Fixed Low-dose Eltrombopag and rhTPO for Immune Thrombocytopenia Coronavirus disease 19 infection, Immune thrombocytopenic purpura eltrombopag plus recombinant human thrombopoietin (sc, idiopathic thrombocytopenic purpura/thrombocytopenia/aplastic anemia), 3SBio Thrombopoietin receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) People's Hospital Peking University China 2020-08-31 2022-06-30 FLOWER, ITP-PKU019, NCT04518878 Phase 1 Clinical Not yet recruiting 1 22 Months 30 Xiaohui Zhang, MD, Xuelin Dou, MD 2020-08-27
Toclizumam Versus Dexamethasone in Severe Covid19 Cases Coronavirus disease 19 infection Variable regimens including azithromycin , hydroxychloroquine , methylprednisolone (Pfizer) , tocilizumab Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) South Valley University Egypt 2020-03-01 2020-08-05 NCT04519385, SOUTHVU Phase 2 Clinical Completed 1 5 Months 69 Alaa R rashad, MD 2020-08-21
Study for Quantitative Analysis of the Recovered COVID-19 Patients by [18]F-FDG-PET/CT Coronavirus disease 19 infection [18]F-FDG alone, computed tomography alone, positron emission tomography alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fifth Affiliated Hospital, Sun Yat-Sen University China 2020-07-01 2023-07-31 NCT04519255, ZDWY.FZYX.008 Phase Not Applicable No longer recruiting 1 37 Months 60 Hong Shan, Ph.D 2020-08-21
CSL-324 in COVID-19 Coronavirus disease 19 infection, Viral pneumonia Standard of care alone, CSL-324 plus remdesivir COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, GCSF receptor antagonist, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) CSL Behring, CSL Ltd 2020-08-31 2021-05-31 CSL324_COVID-19, NCT04519424 Phase 2 Clinical Not yet recruiting 0 9 Months 124 2020-08-21
A clinical study to assess XoGlo in the treatment of COVID-19 related inflammatory disease Coronavirus disease 19 infection, Inflammatory disease, Respiratory distress syndrome XoGlo alone Kimera Labs US Phase Not Applicable Planned 1 160 2020-08-20
A human-challenge trial to evaluate CodaVax-COVID in healthy subjects Coronavirus disease 19 infection CodaVax-COVID alone Healthy volunteers accepted Codagenix Inc Phase Not Applicable Planned 0 2020-08-20
CORONA: Evolution of COVID-19 in Anticoagulated or Antiaggregated Patients Coronavirus disease 19 infection acenocoumarol alone, apixaban alone, aspirin alone, cangrelor alone, clopidogrel alone, dabigatran etexilate mesylate alone, dipyridamol alone, edoxaban alone, prasugrel alone, rivaroxaban alone, ticagrelor alone, vitamin K antagonist therapy alone, warfarin alone Factor IIa antagonist, Factor IX antagonist, Factor VII antagonist, Factor X antagonist, Factor Xa antagonist, P2Y12 purinoceptor antagonist, Protease-activated receptor-1 antagonist, Vitamin K epoxide reductase inhibitor Fundacio Institut De Recerca De L'Hospital De La Santa Creu I Sant Pau Spain 2020-04-01 2020-06-30 CORONA, IIBSP-COV-2020-24, NCT04518735 Phase Not Applicable Completed 1 3 Months 1707 2020-08-21
On-Line Collectives in Mental Health: Transdisciplinary Action for Groups Vulnerable to COVID-19 Coronavirus disease 19 infection online intervention sessions alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul Universidado de Passo Fundo Brazil 2020-07-15 31919020.6.1001.5342, 4.164.222, RBR-4vy54v, U1111-1253-9181 Phase Not Applicable Not yet recruiting 1 500 Ana Luisa Sant'Anna Alves, Silvana Alba Scortegagna 2020-08-21
Study Assessing the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Repeated Subcutaneous Doses of Anti-Spike (S) SARS-CoV-2 Monoclonal Antibodies (REGN-10933 + REGN-10987) in Adult Volunteers as Related to COVID-19 Coronavirus disease 19 infection REGN-CoV2 alone COVID19 Spike glycoprotein inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Regeneron Pharmaceuticals Inc US 2020-07-26 2021-07-06 NCT04519437, R10933-10987-HV-2093 Phase 1 Clinical Recruiting 4 11 Months 420 Clinical Trial Management, Clinical Trials Administrator 2020-08-21
COVIDDEPERINAT: Effect of Tele-consultation in Addition With Psychiatric Follow-up During COVID-19 in Women Who Have Medical History of Post-partum Depression Anxiety disorder, Coronavirus disease 19 infection, Postnatal depression tele-consultation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-09-30 2020-09-30 APHP200878, COVIDDEPERINAT, NCT04516668 Phase Not Applicable Not yet recruiting 1 250 Emmanuelle Corruble, Pr, Florence Gressier, Dr 2020-08-21
Renal Biomarkers in AKI and COVID-19 Coronavirus disease 19 infection, Renal injury, Viral pneumonia metabolomic test alone, tocilizumab alone, urinary IGFBP7 test alone, urinary IL-6 test alone, urinary NGAL test alone, urinary TIMP-2 test alone, viral load test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto Nacional de Enfermedades Respiratorias Mexico 2020-06-01 2020-09-30 C26-20, NCT04517630 Phase Not Applicable Recruiting 1 4 Months 90 Amy B. Peralta Prado, MD, Santiago Avila Rios, PhD, Santiago Avila Ríos, PhD, Santiago Ávila Ríos, PhD 2020-08-22
COMETS: Coronavirus Studied by Metagenomics in ARDS COVID-19 Patients Coronavirus disease 19 infection, Respiratory distress syndrome MetaMIC software alone, Nextera XT kit alone, NovaSeq (Illumina) alone, QiaSymphony alone, Stranded TruSeq Total RNA (Illumina) alone, biological sampling alone, metagenomic and transcriptomic analysis alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-03-09 2020-12-31 APHP200418, COMETS, NCT04516486 Phase Not Applicable No longer recruiting 1 9 Months 180 Christophe Rodriguez, PharmD, PhD 2020-08-21
COVID-19 and SARS-CoV-2 Detection in Saliva Coronavirus disease 19 infection TaqPath RT-PCR alone, biological sampling alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ambry Genetics Corp Crozer-Keystone Health System, St. Joseph Hospital of Orange, The Saratoga Hospital US 2020-05-21 2020-12-30 COV_20_001, NCT04517682 Phase Not Applicable Recruiting 1 7 Months 300 Brigette Tippin Davis, PhD 2020-08-26
CONVINCE: Corona Virus Edoxaban Colchicine (CONVINCE) COVID-19 Coronavirus disease 19 infection, Thrombosis colchicine alone, edoxaban alone, colchicine plus edoxaban Factor Xa antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Inselspital, Berne Daiichi Sankyo Co Ltd, Daiichi Sankyo Europe GmbH Switzerland 2020-10-01 2021-12-31 CONVINCE, CONVINCE VERSION 1.0 12052020, NCT04516941 Phase 3 Clinical Not yet recruiting 2 15 Months 420 Olga Deckarm, MD, Stephan Windecker, Stephan Windecker, MD, Stephan Windecker, Prof. Dr. 2020-08-21
CPCP: Convalescent Plasma for COVID-19 Patients Coronavirus disease 19 infection convalescent COVID-19 plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Vinmec Research Institute of Stem Cell and Gene Technology National Institute for Infectious And Tropical Diseases, National Institute of Hematology and Blood Transfusion, Vietnam, National Institute of Hygiene and Epidemiology, Vietnam Vietnam 2020-08-01 2020-12-30 CPCP, ISC.20.11, ISC.20.11.1, NCT04516954 Phase 0 Clinical Recruiting 1 4 Months 10 2020-08-21
Hyperbaric oxygen therapy for hospitalized patients with COVID-19 Coronavirus disease 19 infection hyperbaric oxygen therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Federal University of Juiz de Fora (UFJF), Universidade Federal de Minas Gerais Hospital e Maternidade Therezinha de Jesus Brazil 2020-08-18 31831420.9.1001.5149, 4.137.642, RBR-2fvjjm, U1111-1253-2793 Phase Not Applicable Not yet recruiting 1 40 Daniel Baumfeld, José da Mota Neto, Rafael Zambelli Pinto 2020-08-21
APC Trial: Randomized, study to evaluate early prone position in patients with COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome prone position alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Brasília Brazil 2020-08-30 33576620.9.1001.5455, 4.151.555, APC Trial, RBR-2k66ft, U1111-1253-7949 Phase Not Applicable Not yet recruiting 1 200 Rodrigo Santos Biondi 2020-08-19
HSD3B1 Gene Polymorphisms With Outcomes in SARS-CoV-2 Infected Patients Coronavirus disease 19 infection RNA sampling alone, Sanger sequencing alone, formalin-fixed paraffin embedded tissue blocks alone, polymerase chain reaction alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Oncology Institute of Southern Switzerland Institute of Oncology Research (Switzerland), Istituto Cantonale di Patologia Switzerland 2020-09-01 2021-08-31 COVID19-GENEEXP, NCT04516850 Phase Not Applicable Not yet recruiting 2 12 Months 500 Christian Garzoni, MD, Ricardo Pereira Mestre, Ricardo Pereira Mestre, MD 2020-08-27
ELABORATE-19: Eltrombopag Plus rhTPO Versus Eltrombopag for ITP During the COVID-19 Pandemic Coronavirus disease 19 infection, Immune thrombocytopenic purpura eltrombopag plus recombinant human thrombopoietin (sc, idiopathic thrombocytopenic purpura/thrombocytopenia/aplastic anemia), 3SBio Thrombopoietin receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) People's Hospital Peking University China 2020-08-31 2022-08-31 ELABORATE-19, ITP-PKU020, NCT04516837 Phase 2 Clinical Not yet recruiting 1 24 Months 120 Xiaohui Zhang, MD, Xuelin Dou, MD 2020-08-21
Therapeutic Use of Convalescent Plasma in the Treatment of Patients With Moderate to Severe COVID-19 Coronavirus disease 19 infection, Viral pneumonia COVID-19 convalescent plasma alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) South African National Blood Service South Africa 2020-09-03 2022-07-31 NCT04516811, PROTECT-PATIENT TRIAL Phase 3 Clinical Not yet recruiting 1 22 Months 600 Cynthia Nyoni, Karin vandenBerg, Dr, Mpumi Maxebengula, BCom, Sean Wasserman, A/Professor 2020-08-21
BVAC19: Blood Volume Assessment in COVID-19 ICU Patients Coronavirus disease 19 infection BVA-100 software package alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) NYU Langone Health US 2020-08-01 2021-02-01 20-00896, BVAC19, NCT04517695 Phase Not Applicable Recruiting 1 6 Months 30 Jan Bakker, MD, PhD 2020-08-20
COVID-TRUST: Impact of Perceived Control on Operational Strain: a Study of COVID-19 Pandemic Caregivers and Military Personnel on Operational Missions Coronavirus disease 19 infection, Psychiatric disorder electrocardiogram alone, electrodermal activity alone, emotional stimulation assessment alone, saliva sampling alone, work-related stress assessment alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Direction Centrale du Service de Sante des Armees France 2020-09-30 2021-02-28 2020-COVID19-28, COVID-TRUST, NCT04517136 Phase Not Applicable Not yet recruiting 1 5 Months 60 Damien CLAVERIE, MD, PhD, Khaldoun KUTEIFAN, MD 2020-08-20
fenix: Evaluation of symptoms, respiratory, pulmonary image and inflammation in patients who have been hospitalized for coronavirus infection in the period of a year, multicentric study Coronavirus disease 19 infection, Inflammatory disease, Respiratory disease Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Hospital Beneficiência Portuguesa de Bauru, Hospital Estadual Américo Brasiliense, Hospital Estadual de Bauru, Hospital Of Syrian Lebanese Itatiba S/C Ltd, Incor - Instituto do Coração do Hospital das Clínicas da FMUSP, Irmandade Santa Casa de Misericordia de Araraquara, Unidade de Pesquisa Clínica - Hospital das Clínicas da Faculdade de Medicina de Botucatu, Universidade Federal De Uberlândia - Ufu, Universidade Federal de Sao Paulo - UNIFESP, University Hospital of the Faculty of Medicine of Ribeirão Preto Brazil 2020-06-02 A27072519840, CAAE:31258820.5.1001.5411, CEP: 4.015.191, CEP: 4.121.653, RBR-8j9kqy, fenix Phase Not Applicable Recruiting 1 270 Andre Luis Pereira Alburquerque, Eloara Vieira Machado Ferreira Alvares, Suzana Erico Tanni Minamoto 2020-08-27
Intramuscular Effect of Polymerized Type I Collagen on the Cytokine Storm in COVID-19 Patients Coronavirus disease 19 infection, Inflammatory disease, Pulmonary fibrosis collagen-polyvinylpyrrolidone alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto Nacional de Ciencias Medicas y Nutricion Mexico 2020-08-19 2021-06-19 IRE-3412-20-21-1, NCT04517162 Phase 1 Clinical Not yet recruiting 1 10 Months 90 Daniel Azamar-Llamas, MD, Diego F Hernández-Ramírez, PhD, Elizabeth Olivares-Martínez, PhD, Enrique Ochoa-Hein, MD, Eric Ochoa-Hein, MD, Gonzalo Torres-Villalobos, MD, PhD, Janette Furuzawa Carballeda, Janette Furuzawa-Carballeda, PhD, Luis A Septien-Stute, MD 2020-08-20
canSEROcov: Study of the Specific Seroprevalence of SARS-CoV-2 in a Sample of Patients and Salaried Staff From a French Anti-cancer Center at the End of the Containment Period of the SARS-CoV-2 Pandemic Cancer, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Georges-François Leclerc France 2020-05-12 2020-06-30 2020-A00877-32, NCT04517097, canSEROcov Phase Not Applicable Completed 1 1 Month 1680 2020-08-21
SeroCovEms: Study of SARS-CoV2 Virus (COVID-19) Seroprevalence Among Lyon-Bron Military Health Schools Personnel Coronavirus disease 19 infection Anti-SARS-CoV2 serology test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Direction Centrale du Service de Sante des Armees France 2020-09-30 2020-11-30 2020-COVID19-29, NCT04516928, SeroCovEms Phase Not Applicable Not yet recruiting 1 2 Months 950 Annick BUZENS, MD, Christophe MARTINAUD, MD, PhD, Ludovic KARKOWSKI, MD 2020-08-22
A phase III trial of WHOOP, a wearable device to check on several daily health data in COVID-19 patients Coronavirus disease 19 infection WHOOP alone G42 Healthcare 2020-07-16 Phase 3 Clinical Recruiting 0 2020-08-21
Clinical study to assess the safety and tolerability of administration, directly into a vein, of human umbilical cord and placental blood plasma (Plasmacord) in patients with Severe acute respiratory syndrome resulting from Sars-Cov-2 infection (fever, cough headache, muscle aches and difficulty breathing) Coronavirus disease 19 infection, Respiratory distress syndrome Plasmacord alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cryopraxis Criobiologia Ltda Brazil 2020-07-20 32622920.5.0000.0070, 4.055.744, 4.122.919, RBR-4pfygr, U1111-1256-0705 Phase 1/Phase 2 Clinical Not yet recruiting 1 10 Dayane Vila Nova, Elie Fiss, Maria Helena Nicola 2020-08-20
Halodine Nasal Antiseptic in Patients With COVID-19 Coronavirus disease 19 infection Povidone-Iodine Solution (Halodine LLC) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Halodine LLC 2020-09-01 2020-12-31 HDN-N02-COV24A, NCT04517188 Phase 4 Clinical Not yet recruiting 0 4 Months 40 Samuel B Barone, MD, Samuel Barone, MD 2020-08-21
A Study of AK-119, Anti-CD73 Antibody, a Treatment for COVID-19, in Healthy Subjects Coronavirus disease 19 infection AK-119 alone CD73 antagonist Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Akesobio Pty Ltd Akeso Biopharma Inc New Zealand 2020-09-30 2021-04-30 AK119-101, NCT04516564 Phase 1 Clinical Not yet recruiting 1 7 Months 32 Kon Yew Kwek 2020-08-21
An observational, retrospective study on the protective role of chronic treatment with direct oral anticoagulants in elderly patients with COVID-19 interstitial pneumonia Atrial fibrillation, Coronavirus disease 19 infection, Deep vein thrombosis, Heart disease, Lung embolism, Pneumonia apixaban alone, dabigatran etexilate mesylate alone, edoxaban alone, rivaroxaban alone Factor IIa antagonist, Factor Xa antagonist, Protease-activated receptor-1 antagonist Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Modena and Reggio Emilia Italy Phase Not Applicable Status not specified 1 70 2020-08-19
A multicenter clinical trial to evaluate 10-min rapid point-of-care saliva-based test for detecting active SARS-CoV-2 infections Coronavirus disease 19 infection rapid point-of-care saliva-based test alone Todos Medical Ltd Israel Phase Not Applicable Recruiting 2 2020-08-19
A phase II/III trials to assess safety and efficacy of Dexaneurosone prophylaxis and treatment for early and moderate cases of Covid-19 Coronavirus disease 19 infection dexaneurosone alone Biomed Industries Inc Phase 2/Phase 3 Clinical Planned 0 2020-08-19
Phase III, Double-blind, Placebo-controlled Study of AZD-1222 for the Prevention of COVID-19 in Adults Coronavirus disease 19 infection AZD-1222 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) AstraZeneca plc Biomedical Advanced Research and Development Authority (BARDA), IQVIA RDS Pty Ltd, US Department of Health and Human Services US 2020-08-17 2022-10-05 D8110C00001, NCT04516746 Phase 3 Clinical Not yet recruiting 66 25 Months 30000 Ann Falsey, MD, AstraZeneca Clinical Study Information Center, Magda Sobieszczyk, MD 2020-08-20
A phase II/III trials to assess safety and efficacy of Biomedivir prophylaxis and treatment for early and moderate cases of Covid-19 Coronavirus disease 19 infection traneurocin + atazanavir (oral, COVID-19), NeuroActiva alone AMPA receptor modulator, HIV-1 protease inhibitor Biomed Industries Inc Phase 2/Phase 3 Clinical Planned 0 2020-08-24
Experience of Orthopedic and Spine Center Pakistan During COVID-19 Coronavirus disease 19 infection, Infectious arthritis, Injury, Spinal disease AD cage alone, Ilizarov alone, K wiring alone, acetabulum fixation alone, amputation alone, arthroplasty alone, arthroscopic anterior cruciate ligament reconstruction alone, arthrotomy alone, bilateral total hip replacement alone, bilateral total knee replacement alone, biopsy alone, bipolar hemiarthroplasty alone, cannulated screw fixator alone, disc excision alone, dura repair alone, dynamic compression plate alone, dynamic hip screw alone, elbow reconstruction alone, external fixator (AO Foundation) alone, implant removal alone, intramedullary nail alone, knee arthroscopy alone, lateral mass screw fixation alone, locking compression plate alone, meniscectomy alone, pelvic fixation alone, plaster of paris (POP) alone, posterior cervical decompression alone, tension band wiring technique alone, transpedicular screw fixation alone, unilateral total hip replacement alone, unilateral total knee replacement alone, vacuum assisted closure (VAC) dressing alone, wound wash alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ghurki Trust Teaching Hospital Pakistan 2020-03-19 2020-08-15 30, NCT04516824 Phase Not Applicable Completed 1 4 Months 2160 Dr. Ashfaq Jadoon, Dr. Majid Cheema, Dr. Samreen Sadiq, Prof Amer Aziz, Prof Rizwan Akram, Prof. Atiq Uz Zaman, Prof. Ijaz Ahmad 2020-08-20
A phase II/III trials to assess safety and efficacy of Nanomedivir for prophylaxis and treatment for early and moderate cases of Covid-19 Coronavirus disease 19 infection Nanomedivir alone AMPA receptor modulator Biomed Industries Inc Phase 2/Phase 3 Clinical Planned 0 2020-08-19
A phase I single-IV administration ascending dose study to assess the safety and tolerability of HFB-30132A in healthy subjects Coronavirus disease 19 infection HFB30132A alone Healthy volunteers accepted HiFiBio US Phase 1 Clinical Planned 1 2020-08-19
A Phase 1a study was to assess safety, tolerability and pharmacokinetics of remdesivir in healthy volunteers Coronavirus disease 19 infection remdesivir (inhalant solution, COVID-19), Gilead alone COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Healthy volunteers accepted Gilead Sciences Inc US Phase 1b Clinical Not yet recruiting 1 60 2020-08-19
A case-report study of acute hemolysis induced by hydroxychloroquine in a patient with severe COVD-19 related lung injury Coronavirus disease 19 infection, Viral pneumonia hydroxychloroquine plus lopinavir + ritonavir HIV protease inhibitor Male, European Ancestry Universita di Verona Phase Not Applicable Status not specified 0 1 2020-08-19
>A clinical trial of Sputnik V for the prevention of Covid-19 in Venezuela Coronavirus disease 19 infection Sputnik V alone COVID19 Spike glycoprotein modulator Venezuelan Institute of Scientific Investigations (IVIIC) Venezuela Phase Not Applicable Planned 1 2020-08-19
COVIDET: Assessment of SARS-CoV-2 Seroprevalence in Detention Coronavirus disease 19 infection venous blood test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-09-01 2021-01-01 APHP200667, COVIDET, NCT04516512 Phase Not Applicable Not yet recruiting 1 4 Months 2500 Anne Dulioust, MD, PhD, Anne Dulioust, MD,PHD, Anne Maie Roque-Afonso, MD, MPH, Guillaume Mellon, MD, MPH, Guillaume Mellon, MD,MPH 2020-08-20
Efficacy of L Plantarum and P Acidilactici in Adults With SARS-CoV-2 and COVID19 Coronavirus disease 19 infection, Dyspnea Variable regimens including Lactobacillus plantarum CECT 7484 , Lactobacillus plantarum CECT 7485 , Lactobacillus plantarum CECT7481 , P acidilactici CECT 7483 Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) AB Biotics Hospital General Dr. Manuel Gea González, Innovacion y Desarrollo de Estrategias en Salud 2020-08-19 2021-01-31 ABB-COVID19, NCT04517422 Phase Not Applicable Not yet recruiting 0 5 Months 300 Pedro Gutierrez-Castrellon, MD, PhD 2020-08-20
Hydroxychloroquine ineffective as a preventive antiviral against COVID-19 patiients with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) Coronavirus disease 19 infection hydroxychloroquine alone Case Western Reserve University Phase Not Applicable Status not specified 0 159 Mendel Singer, PhD, MPH 2020-08-19
An observational, cautionary case report to evaluate the outcomes of tocilizumab therapy in patients with COVID-19-induced cytokine release syndrome Coronavirus disease 19 infection tocilizumab alone University of New Brunswick Phase Not Applicable Status not specified 0 2 2020-08-25
SOBERANA 01: Phase I/II, randomized, controlled, adaptive, double-blind and multicenter study to evaluate the safety, reactogenicity and immunogenicity, of the prophylactic FINLAY-FR-1 anti-SARS-CoV-2 Vaccine Candidate in a two-doses schedule(COVID-19) Coronavirus disease 19 infection FINLAY-FR-1 anti-SARS-CoV-2 Vaccine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Finlay Institute Cuba 2020-08-24 2021-01-11 IFV/COR/04, RPCEC00000332, SOBERANA 01 Phase 1/Phase 2 Clinical Not yet recruiting 1 4 Months 676 Beatriz Paredes Moreno, Meiby Rodríguez Gonzalez, Sonia Perez Rodriguez 2020-08-20
Developing the online program of SST Autism, Coronavirus disease 19 infection Online meeting system alone, Social skills training program alone Children (6-12 yrs) Osaka University Japan 2020-08-15 UMIN000041437 Phase Not Applicable Not yet recruiting 1 100 TOMOKA YAMAMOTO 2020-08-27
Garlic and cinnamon on the treatment of patients with corona Coronavirus disease 19 infection cinnamon essential oil (Zardband pharmaceutical company) alone, garlic essential oil (Amin Pharmaceutical Company) alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sabzevar University of Medical Sciences Iran 2020-08-22 IRCT20200705048011N1, ir.medsab.rec.1399.072 Phase Not Applicable Recruiting 1 45 Dr.Fereshte Ghorat, Nasrin Fazel 2020-08-24
Famotidine and COVID-19 Coronavirus disease 19 infection Variable regimens including atazanavir , atazanavir + ritonavir , chloroquine phosphate , famotidine (Chemidarou Pharmaceutical Company) , hydroxychloroquine sulfate , lopinavir + ritonavir HIV GAG POL polyprotein inhibitor, HIV GAG protein inhibitor, HIV protease inhibitor, HIV-1 protease inhibitor Bandare-abbas University of Medical Sciences Iran 2020-06-21 IR.HUMS.REC.1399.255, IRCT20200509047364N2 Phase 3 Clinical Recruiting 1 20 Dariush Hooshyar, Dr. Mehdi Hassaniazad, Dr. Mitra Kazemijahromi, Dr. Teamur Aghamolaei 2020-08-19
Giloy Gomutra Capsule, Asthi churna aur Kamdhenu Asava ka vaishvik mahamari Covid-19 par logo ka anubhav aur Chikitsakiya prabhava ka Ankalan Coronavirus disease 19 infection Variable regimens including Asthi Churna , Ayurvedic Giloy Gomutra , Kamdhenu Asava Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bansi Gir Gaushala India 2020-08-18 CTRI/2020/08/027083 Phase Not Applicable Not yet recruiting 2 100 Dr Dineshchandra H Pandya, Dr Urvi Pandya 2020-08-19
Effects of chest physiotherapy in COVID-19 patients with respiratory infection Coronavirus disease 19 infection, Respiratory tract infection chest physiotherapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Semnan University of Medical Sciences Iran 2020-09-20 IR.SEMUMS.REC.1399.111, IRCT20160808029264N9 Phase 2/Phase 3 Clinical Not yet recruiting 1 44 Dr Parviz Kokhaei, Dr Rasool Bagheri, Dr. Mohammad Memarian 2020-08-19
Efficacy of N-acetylcysteine in patients with COVID-19 Coronavirus disease 19 infection Variable regimens including N-acetylcysteine , atazanavir + ritonavir , hydroxychloroquine , lopinavir + ritonavir HIV protease inhibitor Iran University of Medical Sciences Iran 2020-05-21 IR.IUMS.REC.1399.206, IRCT20200623047897N1 Phase 3 Clinical No longer recruiting 1 60 Dr. Seyyed Abbas Motevalian, Najmolsadat Atefi, Niloufar Najar Nobari 2020-08-24
COSMIC-19: Investigating the impact of coronavirus infection (COVID-19) on cardiovascular injury using multiple imaging methods Cardiovascular injury, Coronavirus disease 19 infection CT coronary angiogram alone, PET scan alone, cardiac MRI alone, flurodeoxyglucose alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Aga Khan University Hospital United Kingdom Research & Innovation Kenya 2020-03-23 2020/IERC-74, COSMIC-19, ISRCTN12154994 Phase Not Applicable Recruiting 1 50 Dr Anoop Shah, Dr Shirjel Alam 2020-08-19
Home Management of Adult Egyptian Mild COVID-19 Cases Coronavirus disease 19 infection telemedicine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Cairo University Egypt 2020-07-01 2021-03-31 NCT04515199, TELEMEDICINE IN MILD COVID-19 Phase Not Applicable Recruiting 1 9 Months 400 Ibrahim El Ebrashy, Professor, Maha Hossam Al-Din Ibrahim, Professor, Mohamed Tharwat Hegazy, Mohamed Tharwat Hegazy, Lecturer 2020-08-19
UNITY Global: An International Registry of Healthcare Workers to Collect Information on Risk Factors for Developing COVID-19 and the use of preventative therapies Coronavirus disease 19 infection Certara COVID -19 Therapeutics Accelerator Zambia, Senegal, Kenya, Uganda, Nigeria, Zimbabwe, Pakistan, South Africa 2020-08-03 UNITY Global Phase Not Applicable Recruiting 8 10000 Craig Rayner, Roman Casciano 2020-08-18
A Dose-Confirmation Study to Evaluate the Safety, Reactogenicity and Immunogenicity of Vaccine CVnCoV in Healthy Adults Coronavirus disease 19 infection SARS-CoV-2 mRNA vaccine (COVID-19), CureVac alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) CureVac AG 2020-08-17 2021-11-09 CV-NCOV-002, NCT04515147 Phase 2 Clinical Not yet recruiting 0 14 Months 691 Clinical Trial Information 2020-08-19
Perinatal Outcomes and Hematological Parameters in COVID-19 Pregnancies Coronavirus disease 19 infection, Pregnancy disorder Healthy volunteers accepted, Female, Young Adults (18-44 yrs) Ankara City Hospital Bilkent Turkey 2020-03-10 2020-08-10 E1-20-672, NCT04515108 Phase Not Applicable Completed 1 5 Months 108 Esin Merve Erol Koç, MD 2020-08-21
To assess the fear and readiness of medical workers to work in the health care set up in the state of Karnataka during COVID-19 illness after the lock down is over Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Kasturba Medical College, Manipal India 2020-08-18 CTRI/2020/08/027082 Phase Not Applicable Not yet recruiting 1 600 Dr Sadhana N Holla, Prabhleen Kaur Sibal 2020-08-19
Elevated fibrinogen and fibrin degradation product were associated with poor outcome in COVID-19 patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Faculty of Medicine Airlangga University Indonesia 2020-05-05 UMIN000041428 Phase Not Applicable Completed 1 1654 Johannes Nugroho, Maya Ayun 2020-08-26
END CoV-2: Novel Point-of-Care Diagnostic Test for SARS-CoV-2 (COVID-19) Coronavirus disease 19 infection Biospecimen Collection (nasopharyngeal sample) alone, Questionnaire Administration alone Healthy volunteers accepted MD Anderson Cancer Center National Cancer Institute, Rice University US 2020-04-09 2021-04-30 2020-0318, 2020-0318, END CoV-2, NCI-2020-03470, NCT04513990 Phase Not Applicable Recruiting 2 12 Months 1500 Kathleen M Schmeler, Kathleen M. Schmeler 2020-08-20
PENFS COVID-19: Neuromodulation With Percutaneous Electrical Nerve Field Stimulation for Adults With COVID-19 Coronavirus disease 19 infection, Dyspnea, Viral pneumonia Auricular percutaneous neurostimulation alone, Neuro-Stim System (NSS)-2 BRIDGE alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Olive View-UCLA Education and Research Institute US 2020-07-13 2021-07-31 1600899, NCT04514627, PENFS COVID-19 Phase Not Applicable Recruiting 1 12 Months 100 Nader Kamangar, M.D., Rajan Saggar, M.D. 2020-08-20
Safety and efficacy of citrobioShield product in improving immunity in COVID-19 patients via inhalation Coronavirus disease 19 infection CitrobioSheild alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) GERMKILL INDIA India 2020-08-17 CTRI/2020/08/027085 Phase Not Applicable Recruiting 1 20 Dr Himanshu Pophale, Dr R Nagaraja Naidu, Subham Dutta 2020-08-19
SeCoVIHA: COVID-19 Prevalence in HIV-infected Patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopitaux Universitaires de Strasbourg 2020-09-15 2020-09-15 7947, NCT04515225, SeCoVIHA Phase Not Applicable Not yet recruiting 0 500 2020-08-19
Comparision of two barrier devices for placement of tube into trachea(windpipe)in COVID-19 patients Coronavirus disease 19 infection Acrylic box alone, Plastic drape alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gujarat Cancer Society Medical college hospital and research centre India 2020-08-17 CTRI/2020/08/027081 Phase 4 Clinical Not yet recruiting 1 500 Dr Heena Chhanwal 2020-08-19
Melatonin in COVID-19 Coronavirus disease 19 infection, Lung disease hydroxychloroquine sulfate (Amin Pharmaceutical company) plus melatonin (Vana Darou Gostar Pharmaceutical Company) Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bandare-abbas University of Medical Sciences Iran 2020-08-22 IR.HUMS.REC.1399.250, IRCT20200506047323N5 Phase 3 Clinical Recruiting 1 60 Mohammad Fathalipour, Parivash Davoodian, Teamur Aghamolaei 2020-08-24
Evaluation the efficacy of Curcuden 35 in patients with COVID-19 Coronavirus disease 19 infection, Viral pneumonia Curcuden 35 (Alborz Nanomed-Tech Company) alone, national guideline based COVID-19 treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shaheed Beheshti Medical University Alborz Nanomed-Tech Company, Mobtaker Electric Company (METEC) Iran 2020-05-21 IR.SBMU.RETECH.REC.1399.085, IRCT20170128032241N3 Phase 3 Clinical Recruiting 1 20 Maria Tavakoli Ardakani, Maryam Mohajeri, Mehran Azodi, Narges Shakeri, ماریا توکلی اردکانی 2020-08-20
A clinical trial of K-NK-ID101 cell therapy for the potential treatment of COVID-19 Coronavirus disease 19 infection K-NK-ID101 cell therapy alone Kiadis Pharma BV Phase Not Applicable Planned 0 2020-08-18
Evaluate the medicinal effects of both Ayurveda combinations Bio-Immune as Anti-viral and Covalix Vaccoil as alternate to Vaccine of COVID-19 on exposed individuals and Covid19 contact Coronavirus disease 19 infection Bio-Immune powder alone, Covalix Vaccoil liquid alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Leaf BioLab Leaf Research Institute India 2020-08-20 BICV19P, CTRI/2020/08/027084, U1111-1256-7669 Phase Not Applicable Not yet recruiting 2 61000 AMIT DUTTA 2020-08-19
A randomized, double-blind, placebo-controlled pilot clinical study to evaluate ensifentrine delivered via pressurized metered-dose inhaler ("pMDI") formulation as a treatment for patients hospitalized with COVID-19 Coronavirus disease 19 infection ensifentrine (DPI/MDI, respiratory diseases), Verona Pharma alone PDE 3 inhibitor, PDE 4 inhibitor Verona Pharma plc US Phase Not Applicable Planned 1 2020-08-24
Covae: Assessment of the Prevalence and the Impact of the COVID-19 Epidemic in the French Flight Crew in 2020 Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Direction Centrale du Service de Sante des Armees France 2020-09-30 2020-12-31 2020-COVID19-26, Covae, NCT04514874 Phase Not Applicable Not yet recruiting 2 3 Months 500 Marc MONTEIL, MD, Sébastien BISCONTE, MD 2020-08-20
A clinical trial of Sputnik V for the prevention of Coronavirus disease 19 infection Coronavirus disease 19 infection Sputnik V alone COVID19 Spike glycoprotein modulator Instituto De Tecnologia Do Parana of Brazil Russian Direct Investment Fund Phase Not Applicable Planned 0 2020-08-24
A phase IIa clinical trial to assess teh efficacy of NVX-CoV2373, Novavax COVID-19 vaccine candidate Coronavirus disease 19 infection NVX-CoV2373 alone COVID19 Spike glycoprotein modulator Novavax Inc Bill & Melinda Gates Foundation South Africa Phase 2b Clinical Recruiting 1 2665 Gregory M. Glenn, Shabir Madhi 2020-08-24
A phase II/III study to evaluate TLC-19 in patients with coronavirus disease 2019 (COVID-19) Coronavirus disease 19 infection TLC-19 alone Taiwan Liposome Co US Phase 2/Phase 3 Clinical Planned 1 2020-08-18
Benefit and Harm of Angiotensin Converting Enzyme Inhibitor and Angiotensin Receptor Blocker in COVID-19 Patients: A Review Protocol of Systematic Review and Meta-Analysis Acute lung injury, Cardiac failure, Cardiovascular disease, Coronavirus disease 19 infection, Myocardial infarction, Myocarditis, Stroke ARB therapy alone, Angiotensin Converting Enzyme Inhibitor therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitas Airlangga Asia, Indonesia 2020-07-30 UMIN000041430 Phase Not Applicable Recruiting 1 Eka Utami, Johanes Nugroho 2020-08-20
A phase I trial to evaluate the pharmacokinetic and safety of TLC-19 in healthy subjects Coronavirus disease 19 infection TLC-19 alone Healthy volunteers accepted Taiwan Liposome Co Taiwan Phase 1 Clinical Planned 1 2020-08-18
Prognostic role of coagulation profiles in predicting in-hospital mortality of COVID-19 patients: a meta-analysis Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Faculty of Medicine Airlangga University Indonesia, Asia 2020-07-16 UMIN000041427 Phase Not Applicable Recruiting 1 8397 Eka Mulia, Johanes Nugroho 2020-08-20
The role of markers (NLR, IL-6, D-dimer) in COVID-19 patients and it’s co-relationship with oxygenation - retrospective, observational study in Tertiary care COVID ICU Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Vardhman Mahavir Medical College & Safdarjung Hospital India 2020-08-22 CTRI/2020/08/027110 Phase Not Applicable Not yet recruiting 1 250 Arin Choudhury 2020-08-19
Effect of N95 mask in our body study in high volume center Coronavirus disease 19 infection N95-mask alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Vardhman Mahavir Medical College & Safdarjung Hospital India 2020-08-18 CTRI/2020/08/027112 Phase Not Applicable No longer recruiting 1 Arin Choudhury 2020-08-18
Personal Experience During COVID-19 Pandemic Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sri Ramachandra Institute of Higher Education and Research India 2020-08-22 CTRI/2020/08/027118 Phase Not Applicable Not yet recruiting 1 1000 Dr D Rohith Khanna, Dr Vivian Kapil V 2020-08-19
A clinical trial to know the efficacy and safety of herbal product Virowin in combination with Energy-Z capsule in treating mild to moderate COVID-19 patients Coronavirus disease 19 infection Energy Z capsules plus Virowin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Amulya Herbs India 2020-08-20 CTRI/2020/08/027120, PHAR/CT/Virowin/14072020/01, VERSION 01 Phase 4 Clinical Not yet recruiting 1 Baburao Vikram, Dr K Sunil Naik, Dr Parikshit Bansal 2020-08-19
A Clinical Study to Understand the Effect of Inosine Pranobex in COVID-19 Patients when used along with the Standard of Care in COVID Patients Coronavirus disease 19 infection inosine pranobex alone, standard of care  alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Themis Medicare Ltd India 2020-08-20 CTRI/2020/08/027162, TML/IAD/2020/01 Version 1.1 Phase 2 Clinical Not yet recruiting 5 60 Dr Ashok Kumar Swain, Dr Dnyaneshwar Halnor, Dr Jayanthi C R, Dr Mohammad Siddiqui, Dr Padmaja Saraf, Dr Ranganath T Ganga, Mr Sangameshwar Iyer 2020-08-20
COViPP: The COVID-19 Outbreak in Pasir Puteh District in Kelantan, Malaysia: An Overview Coronavirus disease 19 infection PEJABAT KESIHATAN DAERAH PASIR PUTEH Malaysia 2020-08-15 2020-09-19 54847, COViPP, NMRR-20-1734-54847, PKDPP2020/1 Phase Not Applicable Status not specified 1 1 Month Doctor Teh Muthmainnah Binti Md Suhaimi 2020-08-20
Cross-Sectional CFAR HIV/COVID Study Coronavirus disease 19 infection, HIV infection COVID-19 specific antibody testing alone, real-time polymerase chain reaction assay alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) University of Miami Miami Center for AIDS Research US 2020-08-12 2021-03-31 20200802, NCT04514016 Phase Not Applicable Recruiting 1 7 Months 100 Adriana Drada, CRC, Charles Mitchell, MD, Grace Alvarez, CRC 2020-08-19
Randomized Clinical Trial of Intranasal Dexamethasone as an Adjuvant in Patients With COVID-19 Coronavirus disease 19 infection, Interstitial lung disease, Respiratory disease, Respiratory distress syndrome, Viral pneumonia dexamethasone alone, standard care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Universidad Nacional Autonoma De Mexico Hospital General de Mexico, Instituto Nacional De Neurología Y Neurocirugía Manuel Velasco Suárez, Instituto Nacional de Cardiologia Ignacio Chavez Mexico 2020-08-31 2020-12-31 DI/20/407/04/36, NCT04513184 Phase 2 Clinical Recruiting 4 4 Months 60 Ana María H Espinosa-García, PhD, Edda Sciutto, PhD, Graciela A Cárdenas-Hernández, PhD, Graciela Cárdenas-Hernández, PhD, Joselín Hernández-Ruiz, PhD, María Chavez-Canales, PhD, María Chávez-Canales, PhD 2020-08-24
Convalescent Plasma in the Early Treatment of High-Risk Patients With SARS-CoV-2 (COVID-19) Infection Coronavirus disease 19 infection, Multiple organ failure, Respiratory failure, Septic shock convalescent plasma cells alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Norton HealthCare US US 2020-08-14 2021-12-31 20-N0124, NCT04513158 Phase 2 Clinical Recruiting 4 16 Months 100 Don A Stevens, MD, Jackie Bourke, RN, Jayne Carwile, RN, MSN, Joseph J Maly, MD, Joseph M Flynn, DO, MPH, Khuda D Khan, MD, PhD, Marti Gardner, MSN, APRN, Paul Schulz, MD 2020-08-26
To Evaluate Efficacy And Safety Of 'viracide' In The Management Of Corona Virus Disease 2019 (Covid-19) Coronavirus disease 19 infection SOC Therapy alone, Viracide alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Smt Kashibai Navale Medical College and Hospital India 2020-08-20 CTRI/2020/08/027106 Phase Not Applicable Not yet recruiting 2 120 Dr Shreepad Bhat, Dr Vikas Deshmukh, Mr Sohal Pendse 2020-08-20
Cross Sectional Retrospective Analysis Of Clinical Sign Of Breathlessness In Sitting And Supine Position In COVID-19 Patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Seth GS Medical College India 2020-08-13 CTRI/2020/08/027104, EC/OA-114/2020 Phase Not Applicable Not yet recruiting 1 45 Dr Amita Athavale 2020-08-20
Novel Safe Transport Medium and Rapid RNA Extraction Method for COVID-19 Coronavirus disease 19 infection Rapid Solution-Based RNA Extraction Method alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) B. J. Medical College, Pune, BioEra Life Sciences Pvt Ltd India 2020-08-19 CTRI/2020/08/027103 Phase Not Applicable Not yet recruiting 1 100 Dr Rajesh Karyakarte 2020-08-19
Colchichine use for preventing COVID infection in hemodialysis patients Coronavirus disease 19 infection colchicine alone, dialysis alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Narayana Hrudayalaya LTD India 2020-08-15 CTRI/2020/08/027102 Phase 2 Clinical Not yet recruiting 1 100 Dr Krishna Kishore C, DrAlben Sigamani 2020-08-20
Role of Digital communication in COVID-19 isolation facilities an observation study Coronavirus disease 19 infection internet based audio-visual communication alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) National Cancer Institute, Jhajjar, AIIMS India 2020-09-01 CTRI/2020/08/027094 Phase Not Applicable Not yet recruiting 1 100 Dr Brajesh Kumar Ratre 2020-08-20
DPC19 study: Disease Profile of Covid-19 in patients admitted at AIIMS, Rishikesh Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute Of Medical Sciences, Rishikesh India 2020-08-25 CTRI/2020/08/027169, DPC19 study Phase Not Applicable Not yet recruiting 1 1000 Prasan Kumar Panda 2020-08-18
Clinical profile of neonates born to mothers with COVID-19 Coronavirus disease 19 infection RT-PCR of Naso pharyngeal swab alone Newborn Infants (up to 5 months) Government Medical College Kannur India 2020-08-30 CTRI/2020/08/027175 Phase Not Applicable Not yet recruiting 1 50 Ambili Susan Jacob 2020-08-18
Clinical trial study to investigate safety and efficacy of ImmunoSEB and ProbioSEB Coronavirus disease 19 infection ImmunoSEB Capsule plus ProbioSEB CSC3 Capsule Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) SRV Hospital India 2020-08-21 CTRI/2020/08/027168, PROCLIN_COVID-005 Phase Not Applicable Not yet recruiting 1 60 Dr Abhay Vispute Shantaram 2020-08-18
Psychological Impact of COVID 19 on frontline health care workers Acute stress disorder, Coronavirus disease 19 infection, Psychiatric disorder PPE KIt  alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) AIIMS Jodhpur India 2020-08-20 CTRI/2020/08/027174 Phase Not Applicable Not yet recruiting 1 500 KAMLESH KUMARI 2020-08-18
A randomized, double-blind, placebo-controlled, phase III clinical trial to evaluate the efficacy of NVX-CoV2373 for treatment of COVID-19 Coronavirus disease 19 infection NVX-CoV2373 alone COVID19 Spike glycoprotein modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Novavax Inc UK Government UK 2020-09-30 Phase 3 Clinical Planned 1 9000 2020-08-24
Study of stress, depression and anxiety in healthcare workers doing COVID duty Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Gujarat Cancer Society Medical college hospital and research centre India 2020-08-18 CTRI/2020/08/027166 Phase Not Applicable Not yet recruiting 1 200 Aatman Parikh 2020-08-18
Necessary measures taken for covid positive pregnant women during pandemic Coronavirus disease 19 infection Female, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Sri B. M. Patil Medical College India 2020-08-15 CTRI/2020/08/027173 Phase Not Applicable Not yet recruiting 1 100 DR SHREEDEVI KORI 2020-08-19
Clinical Profile and Outcome of Neonates Born to Mothers with COVID in a Tertiary Care Centre Coronavirus disease 19 infection Newborn Infants (up to 5 months) Sri Ramachandra Institute of Higher Education and Research India 2020-08-16 CTRI/2020/08/027172 Phase Not Applicable Not yet recruiting 1 40 Dr Thinesh Kumar J 2020-08-19
Safety and Efficacy of Anti-SARS-CoV-2 Equine Antibody Fragments (INOSARS) for Hospitalized Patients With COVID-19 Coronavirus disease 19 infection, Viral pneumonia anti-SARS-CoV-2 immunoglobulin F(ab')2 fragment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital San Jose Tec de Monterrey Mexico 2020-10-20 2021-06-20 INOSARS-COV-2 TECSALUD, NCT04514302 Phase 1/Phase 2 Clinical Not yet recruiting 1 8 Months 51 Alejandro Torres-Quintanilla, MD, MSc, José F Castilleja-Leal, MD, Servando Cardona-Huerta, MD, Ph. D. 2020-08-18
COVITA: The Corona and COVID-19 Study in Telemark and Agder Coronavirus disease 19 infection antibody testing alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sykehuset Telemark Aalborg Universitet, London School of Hygiene and Tropical Medicine, Norwegian Institute of Public Health, Sykehuset Sorlandet Hf, Universiteit Leiden Norway 2020-07-01 2035-12-31 COVITA, COVITA, NCT04514003 Phase Not Applicable Recruiting 1 186 Months 5000 Anne Kristin M. Fell, PhD 2020-08-19
COVID-19 Global Rheumatology Alliance Coronavirus disease 19 infection, Rheumatoid arthritis University of California Canada, New Zealand, Germany, Brazil, Mexico, Sweden, Egypt, US, Chile, Finland, France, Czech Republic, Denmark, Iceland, Iran, Norway, Austria, Italy, UK, Belgium, Australia, India, Argentina, Algeria 2020-03-16 CTRI/2020/08/027165 Phase Not Applicable Not yet recruiting 26 3000 Dr Amita, Sharath Kumar 2020-08-18
National Clinical Registry of COVID 19 Coronavirus disease 19 infection Indian Council of Medical Research India 2020-08-17 CTRI/2020/08/027164 Phase Not Applicable Not yet recruiting 1 10000 Dr Anup Agarwal, Dr Aparna Mukherjee 2020-08-18
BRICOAKI TRIAL: Measurement of renal biomarker in COVID-19 associated acute renal failure Coronavirus disease 19 infection, Renal injury Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Medical Sciences Patna India 2020-08-25 BRICOAKI TRIAL, CTRI/2020/08/027171 Phase Not Applicable Not yet recruiting 1 75 Neeraj Kumar 2020-08-21
Study to check the safety and immune response of a COVID-19 vaccine in healthy Indian adults Coronavirus disease 19 infection Covishield (SII-ChAdOx1 nCoV-19) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Serum Institute of India Ltd Indian Council of Medical Research India 2020-08-24 CTRI/2020/08/027170, ICMR/SII-COVISHIELD Phase 2/Phase 3 Clinical Not yet recruiting 17 1600 Dr Ashish Bavdekar, Dr B Devi Madhavi, Dr B S Garg, Dr Kamran Zaman, Dr Kiranjit Singh, Dr Krishna Pandey, Dr Madhu Gupta, Dr Muralidhar Tambe, Dr Nithya Gogtay, Dr Pankaja Raghav, Dr Prasad Kulkarni, Dr Praveen Kulkarni, Dr Ramkrishnan, Dr Randeep Guleria, Dr Renuka Munshi, Dr Sanjay Lalwani, Dr Sushant Meshram, Dr T S Selvavinayagam 2020-08-23
Pso-Vac: Educational Needs On Vaccines for Biological Patients With Psoriasis Coronavirus disease 19 infection, Psoriasis biological therapy alone, vaccine education alone Dermatrials Research Canada 2020-08-13 2020-10-13 NCT04513847, PSO-VAC, Pso-Vac Phase Not Applicable Not yet recruiting 1 2 Months 1000 Heather Le, Ronald Vender MD FRCPC 2020-08-19
Ashwagandha in the prevention of COVID-19 in Health Care workers Coronavirus disease 19 infection Ashwagandha alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Central Council for Research in Ayurvedic Sciences, Ministry of Ayush India 2020-08-23 AYUSH- CRD-HCW-01, CTRI/2020/08/027163 Phase 2/Phase 3 Clinical Not yet recruiting 1 400 Dr Arvind Chopra, Dr Dilip Gode 2020-08-19
Benefit of positioning in COVID-19 patient on Bipap mechnical support Coronavirus disease 19 infection Bipap ventilator alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gujarat Cancer Society Medical college hospital and research centre India 2020-08-15 CTRI/2020/08/027080 Phase 3 Clinical Not yet recruiting 1 100 Dr Carolin Smita Kerketta 2020-08-18
Study of lab investigations among hospitalized COVID-19 patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sri Ramachandra Institute of Higher Education and Research India 2020-08-17 CTRI/2020/08/027079 Phase Not Applicable Not yet recruiting 1 1000 Dr Swathy Moorthy, DrSPThiagarajan 2020-08-18
A randomized, double-blind, placebo-controlled, phase I clinical trial for evaluation of the safety and tolerability of recombinant novel coronavirus vaccines (CHO cells) in healthy people aged 60 years and above Coronavirus disease 19 infection, Viral pneumonia new coronavirus vaccines (CHO cells) alone Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hunan Province Centers for Disease Control and Prevention China 2020-08-20 2020-12-31 ChiCTR2000035691 Phase 1 Clinical Not yet recruiting 1 4 Months 50 Li Fangjun, Zhong Zaixin 2020-08-19
Establishment of surveillance system for individuals diagnosed with COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Tata Memorial Centre India 2020-08-17 CTRI/2020/08/027078 Phase Not Applicable Not yet recruiting 2 1200 Dr Rajesh Dikshit 2020-08-19
Investigator Initiated Study to see the safety and efficacy of adding Thymosin Alpha to existing standard of care in severe COVID patients Coronavirus disease 19 infection Standard of Care alone, Thymosin alpha alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fortis hospital India 2020-08-13 CTRI/2020/08/027061, IITTHY00120 Phase 2 Clinical Not yet recruiting 1 15 Dr Adarsh Shetty, Dr Rahul pandit 2020-08-18
CONFIMID: Evaluation of the Impact of Lock Down and End of Lock Down on the Management of Patients With Inflammatory and Dysimmune Diseases Followed in the Context of IMMINeNT FHU (Rheumatology, Dermatology, Internal Medicine, Pneumology, Gastroenterology, Neurology) Angioedema, Ankylosing spondylitis, Asthma, Atopic dermatitis, Autoimmune disease, Coronavirus disease 19 infection, Crohns disease, Inflammatory disease, Multiple sclerosis, Psoriasis, Rheumatoid arthritis, Scleroderma, Systemic lupus erythematosus, Ulcerative colitis Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Regional Universitaire de Lille France 2020-09-30 2020-11-30 2020_51, 2020_A01596_33, CONFIMID, NCT04513561 Phase Not Applicable Not yet recruiting 1 2 Months 4500 Frédéric DEZOTEUX, MD 2020-08-19
REACARDIOCOVID: Impact of COVID-19 on the Benefit of Cardiac Rehabilitation Coronavirus disease 19 infection, Heart injury Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Groupe Hospitalier Paris Saint-Joseph France 2020-09-01 2021-06-30 NCT04513964, REACARDIOCOVID, READCARDIOCOVID Phase Not Applicable Not yet recruiting 1 10 Months 60 BEAUSSIER Helene, PharmD, pHD, DUC Philippe, MD, Iliou Marie-Christine, MD 2020-08-19
Telemedicine in HIV Care in Buenos Aires Coronavirus disease 19 infection, HIV infection Videoconsult through telemedicine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundacion Ibis , Argentina Argentina 2020-09-01 2022-07-01 NCT04513496, TM HIV BA Phase Not Applicable Not yet recruiting 1 22 Months 4000 2020-08-18
Clinical study of safety, tolerance, and pharmacokinetics of nebulizer (INF-K + anti-inflammatory factor TFF2) in healthy volunteers and exploration of PK/PD fitting modeling in clinical trials of COVID-19 patients Coronavirus disease 19 infection, Viral pneumonia IFN/TFF2 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Shanghai Public Health Clinical Center China 2020-11-02 2023-08-13 ChiCTR2000035633 Phase 0 Clinical Not yet recruiting 1 33 Months 32 Jianqing Xu, Yan Liu 2020-08-20
Allocetra-OTS in COVID-19 Coronavirus disease 19 infection, Multiple organ failure, Respiratory disease Variable regimens including Allocetra , dexamethasone , enoxaparin sodium , remdesivir COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, Low molecular weight heparin, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hadassah Medical Organization Israel 2020-08-01 2021-02-28 DM003, NCT04513470 Phase 1 Clinical Recruiting 1 7 Months 5 Dror Mevorach, MD, Peter V van Heerden, MD 2020-08-19
DEXTERITY Fitbit Pilot Study: Detecting Exacerbation Early Signs of SARS-CoV-2 infection by Fitbit: Pilot Study Coronavirus disease 19 infection fitbit Charge3 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fitbit, Kanazawa University Japan 2020-08-14 DEXTERITY Fitbit Pilot Study, UMIN000041421 Phase Not Applicable Recruiting 2 30 Akihiro Nomura 2020-08-20
A Practical, Pilot, Randomized, Controlled Trial of Valproate Alone or in Combination With Quetiapine for Severe COVID-19 Pneumonia With Agitated Delirium Agitation, Coronavirus disease 19 infection, Delirium, Viral pneumonia Variable regimens including dexmedetomidine , divalproex sodium (oral extended-release), Sanofi , ketamine , midazolam hydrochloride , propofol, AstraZeneca/Fresenius , quetiapine IR 5-HT 2 receptor antagonist, Alpha 2 adrenoceptor agonist, Benzodiazepine receptor agonist, CDKN1A gene modulator, Dopamine D2 receptor antagonist, GABA receptor agonist, Sodium channel inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Miami US 2020-09-01 2021-09-01 20200851, NCT04513314 Phase 4 Clinical Not yet recruiting 1 12 Months 20 Dominique L Musselman, Dominique L Musselman, MD, Dominique Musselman, MD, Sergey Gerasim, MD 2020-08-18
Reliability of Standardized Protocol of Ultrasound of the Lungs in Prediction of Severity of Covid 19-infection Coronavirus disease 19 infection, Lung disease, Viral pneumonia ultrasound alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Jagiellonian University Poland 2020-11-01 2022-02-28 JAGIELLONIANU67, NCT04513210 Phase Not Applicable Not yet recruiting 1 16 Months 300 Jakub M Antczak, MD, Wojciech Jagiełło, MD 2020-08-19
A Digital Companion for Loneliness During the COVID-19 Pandemic: A Feasibility Study Acute stress disorder, Coronavirus disease 19 infection, Psychiatric disorder animated, embodied conversational agent alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Soul Machines Ltd, University of Auckland New Zealand 2020-08-24 ACTRN12620000786998, U1111-1252-6680 Phase Not Applicable Not yet recruiting 2 30 Prof Elizabeth Broadbent 2020-08-24
AFTERCOR: Long-term Impact in Intensive Care Survivors of Coronavirus disease-19 (COVID-19) Cognitive disorder, Coronavirus disease 19 infection, Depression Pulmonary function tests alone, blood draw alone, questionnaires alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The Prince Charles Hospital Wesley Research Institute Germany, Spain, Brazil, Ireland, Japan, Hong Kong, Italy, Argentina, US, Australia, South Africa 2020-08-25 ACTRN12620000799954, AFTERCOR Phase Not Applicable Not yet recruiting 13 200 A/Prof Gianluigi Libassi, Dr Karin Wildi 2020-08-19
Early prone position in patients on spontaneous ventilation Coronavirus disease 19 infection, Respiratory insufficiency early prone position alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) BAHIA SECRETARIA DE SAUDE DO ESTADO, Hospital Geral Roberto Santos Brazil 2020-07-15 34357020.5.0000.5028, 4.149.561, RBR-7d7ngw, U1111-1255-3761 Phase 2/Phase 3 Clinical Recruiting 1 88 Cicero Fontenelle, Jorge Luis Motta Dos Anjos, Ludmilla Campos Gaspar 2020-08-24
A retrospective study to analyze epidemiological and clinical characteristics of persistently asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) carriers Coronavirus disease 19 infection Clinical characteristic analysis alone Zhengzhou University Phase Not Applicable Status not specified 0 26 2020-08-18
MET-Covid: Metformin for Prevention and Outpatient Treatment of COVID-19 Coronavirus disease 19 infection metformin hydrochloride alone AMP activated protein kinase stimulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Minnesota US 2020-09-30 2021-09-30 MET-Covid, METFORMIN, NCT04510194 Phase 2/Phase 3 Clinical Not yet recruiting 1 12 Months 1522 Carolyn Bramante, MD 2020-08-26
National Survey for Mental Health and Well-being (NSMHW) Project Lingap sa Bawat Pamilyang Pilipino Coronavirus disease 19 infection Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of the Philippines Philippines 2020-07-05 2021-05-03 PHRR200804-002806 Phase Not Applicable Status not specified 1 9 Months Cynthia Ramos-Leynes, Erniel Barrios, Evelyn G. Gapuz, John Eustaquio, Maria Lourdes Rosanna E de Guzman, Marilyn Crisostomo, Marissa Pascual, Tomas D. Bautista 2020-08-18
Teleophthalmology in a developing country in light of the COVID-19 Pandemic Coronavirus disease 19 infection Philippine General Hospital Philippines 2020-07-29 PHRR200804-002800 Phase Not Applicable Not yet recruiting 1 Corrina Azarcon, Darby E. Santiago, Felice Katrina T. Ranche 2020-08-17
Safety and efficacy of intranasal delivery of BromAc (Bromelain and Acetylcysteine) in swab positive SARS-CoV-2 COVID-19 patients Coronavirus disease 19 infection BromAc alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mucpharm Pty Ltd Australia 2020-08-17 ACTRN12620000788976p, U1111-1256-2985 Phase 1 Clinical Not yet recruiting 1 30 Miss Sarah Valle, Prof David Morris 2020-08-17
Effect of a Brief Problem Management Intervention on Anxiety and Depression Arising from COVID-19-Related Financial Stress Anxiety disorder, Coronavirus disease 19 infection, Depression Enhanced Treatment as Usual alone, Problem Management Plus alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) UNSW Sydney National Health and Medical Research Council Australia ACTRN12620000787987 Phase Not Applicable Not yet recruiting 1 206 Prof Richard Bryant 2020-08-18
Psychological health condition and effect of psychological couseling of infertile couples receiving ART during novel coronavirus pneumonia (COVID-19) pandemic Coronavirus disease 19 infection, Infertility, Viral pneumonia Psychological counseling alone International Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University China 2020-08-17 ChiCTR2000035362 Phase 0 Clinical Not yet recruiting 1 300 Li Jin, Luting Chen 2020-08-17
COVID-19 Health and wellbeing Trial in Bangladesh Acute stress disorder, Coronavirus disease 19 infection, Depression telecounseling alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Khulna University, Monash University Global Development & Research Initiative Foundation (GDRI) Bangladesh 2020-05-31 ACTRN12620000795998, U1111-1254-7316 Phase Not Applicable No longer recruiting 1 2402 Prof Asadul Islam 2020-08-19
Evaluation of muscle weakness, function and quality of life after Intensive Care Unit discharge in survivors of COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital do Servidor Publico Estadual Brazil 2020-05-20 31759020.4.0000.5463, 4,032,543, RBR-564y4n, U1111-1254-0762 Phase Not Applicable Recruiting 1 90 Lucas Simões Arrebola 2020-08-20
Medical care by video calls in Parkinson's disease patients at Hospital Universitário Walter Cantidio- UFC Coronavirus disease 19 infection, Parkinsons disease telehealth monitoring alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Federal University of Ceara Walter Cantídio University Hospital Brazil 2020-05-12 1111-1253-7783, 31232720.2.0000.5045, 4,009,005, RBR-6pq44p Phase Not Applicable Recruiting 1 100 Danielle Pessoa Lima, Pedro Braga Neto 2020-08-26
Testing of BCG vaccine against COVID-19 Coronavirus disease 19 infection BCG vaccine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidade Federal de Goias Lebanese National Council for Scientific Research Brazil 2020-08-05 31783720.0.0000.5078, 4,158,225, RBR-4kjqtg, U1111-1256-3892 Phase 2 Clinical Recruiting 1 400 Ana Paula Junqueira Kipnis 2020-08-17
A phase III trial was to assess COVID-19 vaccinen for the treatment of COVID-19 patients Coronavirus disease 19 infection COVID-19 vaccine (inactivated, Vero cells/intramuscular), Wuhan Institute of Biological Products/Wuhan Institute of Virology, CAS alone Sinopharm China National Biotech Institute Co Ltd Bahrain Phase 3 Clinical Recruiting 1 6000 2020-08-21
Coronavirus (COVID-19) antibody response in healthcare staff: What proportion of healthcare staff have COVID-19 antibodies? How long do the antibodies last? Do the antibodies protect against recurring infection? Coronavirus disease 19 infection antibody testing alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Abbott Rapid Diagnostics Jena GmbH UK 2020-04-22 2021-03-31 CLDG-0504, IRAS 284671, CPMS 46155, ISRCTN15634328 Phase Not Applicable Recruiting 1 11 Months 2000 Prof Patrick T. Kennedy 2020-08-17
Treatment of severe COVID-19 with angiotensin-(1-7) Coronavirus disease 19 infection angiotensin- (1-7) alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Angitec, Universidade Federal de Minas Gerais FAPEMIG Brazil 2020-08-05 4.155.266, CAAE: 34080720.0.1001.5149, RBR-35734p, U1111-1255-7167 Phase 1/Phase 2 Clinical Recruiting 1 130 Ana Luiza Martins Valle, Robson AS Santos 2020-08-18
Software to evaluate clinical, epidemiological data and chest computed tomography to predict which patients with COVID-19 will develop a severe form of the disease Coronavirus disease 19 infection computed tomography alone Diagnosticos da America SA, Hospital Alemao Oswaldo Cruz Brazil 2020-03-02 CAAE: 30548620.0.1001.0008, Número de parecer: 3.968.706, RBR-7dsxsv, U1111-1254-6271 Phase Not Applicable Recruiting 1 500 Felipe Campos Kitamura, Flavia Paiva Proença Lobo Lopes 2020-08-18
A phase I clinical trial of VIB-7734 in the treatment of patients with COVID-19-related acute lung injury Acute lung injury, Coronavirus disease 19 infection daxdilimab alone Leukocyte Ig like receptor A4 modulator Viela Bio 2020-09-30 Phase 1 Clinical Planned 0 2020-08-17
FREEDOM COVID: FREEDOM COVID-19 Anticoagulation Strategy Coronavirus disease 19 infection apixaban alone Factor Xa antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mount Sinai Medical Center US 2020-09-30 2021-06-30 FREEDOM COVID, GCO 20-2115, NCT04512079 Phase 4 Clinical Not yet recruiting 1 9 Months 3600 Anu Lala, MD, Debra Fitzpatrick, MS, Valentin Fuster, MD, PhD, Valentin Fuster, MD,PhD 2020-08-17
A Study to Evaluate The Efficacy, Safety and Immunogenicity of Inactivated SARS-CoV-2 Vaccines (Vero Cell) in Healthy Population Aged >/= 18 Years Old Coronavirus disease 19 infection COVID-19 vaccine (inactivated, Vero cells/intramuscular), Beijing Biological Products Institute/National Institute for Viral Disease Control and Prevention of Chinese Center for Disease Control and Prevention alone, COVID-19 vaccine (inactivated, Vero cells/intramuscular), Wuhan Institute of Biological Products/Wuhan Institute of Virology, CAS alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) China National Biotec Group, Group 42 Holding Ltd, Sinopharm China National Biotech Institute Co Ltd Abu Dhabi Health Services Company PJSC (SEHA), Beijing Biological Products Institute Co Ltd, G42 Healthcare, Wuhan Institute of Biological Products Co Ltd United Arab Emirates, Bahrain 2020-07-16 2021-09-16 CNBG2020003SQ, NCT04510207 Phase 3 Clinical Recruiting 3 14 Months 45000 H.E. Sheikh Abdullah bin Mohammed Al Hamed, Manaf M Alqahtani, Prof., Najiba Abdulrazzaq, Doctor, Nawal AI Kaabi, MD, Walid A Zaher, MD, MSc,PhD, Yunkai Yang, Prof. 2020-08-21
Scaling Mental Healthcare in COVID-19 With Voice Biomarkers Anxiety disorder, Coronavirus disease 19 infection, Depression Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kintsugi Mindful Wellness Inc 2020-09-01 2021-06-30 COV-1, NCT04510519 Phase Not Applicable Not yet recruiting 0 10 Months 50 2020-08-17
COVID-19 in Immunosuppressed Children Coronavirus disease 19 infection, Hematological neoplasm, Kidney transplantation, Liver transplantation Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Instituto D'Or de Pesquisa Hospital Federal de Bonsucesso Brazil 2020-06-30 2021-04-30 062-2020, NCT04511429 Phase Not Applicable Recruiting 2 10 Months 200 Antonio José L A da Cunha, MD, PhD, Arnaldo Prata-Barbosa, MD, PhD, Jaqueline LS Gouveia, MD, Thais L Cleto-Yamane, Thais L Cleto-Yamane, MD, MSc 2020-08-17
MentCovid19RMD: Mental Health Consequences of COVID19 Infection in the French RMD Cohort Autoimmune disease, Autoinflammatory disease, Coronavirus disease 19 infection, Inflammatory disease, Musculoskeletal disease Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Regional Universitaire de Lille FAI²R (Auto-immune and auto-inflammatory rare diseases French network) France 2020-09-30 2021-02-28 2020-A02058-31, 2020_75, MentCovid19RMD, NCT04510467 Phase Not Applicable Not yet recruiting 2 5 Months 1313 Eric Hachulla, MD,PhD 2020-08-18
A clinical study to assess the effects of Meditation (Mindful Happiness) as an additional therapy in asymptomatic and mildly symptomatic covid-19 confirmed cases Coronavirus disease 19 infection Meditation (Mindful Happiness) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Sonalika Social development Society India 2020-08-11 CTRI/2020/08/027032, TG/PRO/CLI/034 Version 1.0 dated 10 July 2020 Phase Not Applicable Not yet recruiting 1 40 Dr Bhageerathi Byrapura Lakshmegowda, Dr Vishwas Vijayadev, Meena Dalal 2020-08-17
COLHEART-19: Colchicine versus Current Standard of Care in Hospitalized Patients With COVID-19 and Cardiac Injury Coronavirus disease 19 infection, Heart injury Covid-19 standard of care alone, colchicine (oral, gout/familial Mediterranean fever), Takeda alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Miami Cardiac and Vascular Institute University of California Los Angeles US 2020-09-01 2022-01-01 152247, COLHEART-19, NCT04510038 Phase 2/Phase 3 Clinical Not yet recruiting 1 16 Months 75 Raul E Herrera, MD, Sandra Chaparro, MD 2020-08-17
AI-COV-19: Artificial Intelligence-assisted Diagnosis and Prognostication in COVID-19 Using Electrocardiograms Coronavirus disease 19 infection CT scans alone, Chest x-ray imaging alone, ECGs alone, RTPCR assay alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Imperial College London Chelsea and Westminster Hospital, Imperial College Healthcare NHS trust, London North West Healthcare NHS Trust UK 2020-05-26 2022-05-01 20HH5967, AI-COV-19, NCT04510441 Phase Not Applicable Recruiting 4 23 Months 2000 Abtehale Al-Hussaini, MRCP PhD, Emmanuel Ako, MRCP PhD, Fu Siong Ng, Jaymin Shah, MRCP PhD, Kiran Patel 2020-08-17
A clinical trial of CYC-065 and seliciclib as potential early treatments for the inflammatory response observed in patients with COVID-19 disease Coronavirus disease 19 infection, Inflammatory disease fadraciclib plus seliciclib Cyclin E inhibitor, Cyclin-dependent kinase-2 inhibitor, Cyclin-dependent kinase-5 inhibitor, Cyclin-dependent kinase-7 inhibitor, Cyclin-dependent kinase-9 inhibitor, MCL1 gene inhibitor Cyclacel Pharmaceuticals Inc University of Edinburgh Phase Not Applicable Planned 0 2020-08-14
CanCovDia: Canakinumab in Patients With COVID-19 and Type 2 Diabetes Coronavirus disease 19 infection, Non-insulin dependent diabetes canakinumab alone Immunoglobulin G1 agonist, Interleukin-1 beta ligand inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Basel Novartis AG, Swiss National Science Foundation Switzerland 2020-09-30 2023-09-30 2020-02008, ME20DONATH2, CanCovDia, NCT04510493 Phase 3 Clinical Not yet recruiting 8 36 Months 116 Alain Golay, MD, Prof., Beat Müller, MD, Prof., Christoph Henzen, MD, Prof., Christoph Stettler, MD, Prof., Felix Beuschlein, MD, Prof., François Jornayvaz, MD, PD, Jonathan Mudry, MD, Lukas Burget, MD, Manuel Battegay, MD, Prof., Marc Donath, MD, Prof., Markus Laimer, MD, Prof., Matthias Hepprich, MD, Michael Brändle, MD, Prof., Nelly Pittteloud, MD, Prof., Patrick Hunziker, MD, Prof., Peter Kopp, MD, Prof., Philipp Schütz, MD, Prof., Roger Lehmann, MD, Prof., Stefan Bilz, MD, PD, Stefan Fischli, MD 2020-08-20
FAMICOV: COVID-19: Epidemiological Study of the Spread of SARS-CoV-2 in the Household of a Person Who Has Had a COVID-19 Disease Coronavirus disease 19 infection COVID-19 IgG / IgM rapid test (manufactured by the firm AAZ) alone, COVID-PRESTO alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre de Recherches et d'Etude sur la Pathologie Tropicale et le Sida France 2020-07-12 2020-11-30 CREPATS 012, FAMICOV, NCT04511949 Phase Not Applicable Recruiting 1 4 Months 500 Christine Katlama, Yasmine Dudoit 2020-08-18
A phase II to assess safety, tolerability and pharmacokinetics (PK) of PLN-74809, as well as exploratory clinical outcome measures in patients hospitalized with severe and critical COVID-19 associated with acute respiratory distress syndrome (ARDS) Coronavirus disease 19 infection, Respiratory distress syndrome PLN-74809 alone Integrin alpha-V/beta-1 antagonist, Integrin alpha-V/beta-6 antagonist Pliant Therapeutics Inc US 2020-12-31 Phase 2 Clinical Planned 1 2020-08-14
Effect of Prolectin-M, a Food Supplement, on SarsCoV2 Viral Copy Numbers: A Proof of Concept, Randomized, Open-Label, Controlled Trial (Prolectin) Coronavirus disease 19 infection Prolectin (Pharmalectin - M) alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Composite Interceptive Med-Science Laboratories Pvt Ltd Pharmalectin Inc India 2020-09-01 2020-09-30 CIMED - 002- 2020, NCT04512027 Phase Not Applicable Not yet recruiting 1 1 Month 10 2020-08-17
STAR-COVID: Telmisartan in Respiratory Failure Due to COVID-19 Coronavirus disease 19 infection, Hypoxia, Respiratory failure, Tachypnea standard care alone, telmisartan alone Angiotensin II receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Regional de Alta Especialidad de Zumpango Instituto Politecnico Nacional Mexico 2020-08-31 2021-04-30 CI/HRAEZ2020/05, NCT04510662, STAR-COVID Phase 2 Clinical Recruiting 1 8 Months 60 Abraham Edgar Gracia-Ramos, MD MSc, Maria Jose Pecero Hidalgo, MD, Maria Jose Pecero-Hidalgo, MD 2020-08-17
PSY-CO-ICU: Psychological Impact of COVID-19 Outbreak on Caregivers Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire de Nimes France 2020-09-30 2021-09-30 LOCAL/2020/JYL-03, NCT04511780, PSY-CO-ICU Phase Not Applicable Not yet recruiting 48 12 Months 5000 Alexandre OUATTARA, Antoine ROQUILLY, Audrey DE JONG, Aurélie GOUEL, Belaid BOUHEMAD, Benoit PLAUD, Benoit VEBER, Bernard ALLAOUCHICHE, Bernard CHOLLEY, Bérangère VIVET, Claire DAHYOT FIZELIER, Claude ECOFFEY, Corentin LACROIX, Emmanuel FUTIER, Emmanuel SAMAIN, Eric PIKNIS, Etienne GAYAT, Francis REMERAND, Frédéric AUBRUN, Gael PITON, Guillaume BESCH, Guylaine LABRO, Gérald CHANQUES, Géralde CHANQUES, Gérard AUDIBERT, Hervé DUPONT, ICHAI Carole, Jacques ALBANESE, Jacques DURANTEAU, Jean Etienne BAZIN, Jean François PAYEN, Jean Luc FELLAHI, Jean Michel CONSTANTIN, Jean Yves LEFRANT, Julien POTTECHER, Jérôme MOREL, Karim ASEHNOUNE, Karim LAKHAL, Lionel VELLY, Mar Olivier FISCHER, Marc LAFFON, Marc LEONE, Marie reine LOSSER, Matthieu BIAIS, Matthieu LE DORZE, Nathalie NATHAN-DENIZOT, Nathan FERRAND, Nicolas BRUDER, Nicolas MONGARDON, Olivier BARBOT, Olivier FOURCADE, Olivier HUET, Olivier JOANNES BOYAU, Olivier LANGERON, Philippe GUERCI, Philippe MONTRAVERS, Philippe SEGUIN, Pierre François PERRIGAULT, Rémy BELLIER, Samir JABER, Sigismond LASOCKI, Sébastien PILI-FLOURY, Thomas KERFORNE, Thomas RIMMELE, Xavier CAPDEVILA, Yazine MAHJOUB, marc GARNIER 2020-08-16
C-MORE: Capturing Multi-organ Effects of COVID-19 Brain injury, Coronavirus disease 19 infection, Heart injury, Liver injury, Lung injury, Renal injury, Respiratory distress syndrome, Viral pneumonia 6 min walk test alone, blood test alone, cardiopulmonary exercise test alone, computed tomography alone, magnetic resonance imaging alone, spirometry alone, transthoracic echocardiography alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Oxford UK 2020-05-13 2023-05-01 282608, C-MORE, NCT04510025 Phase Not Applicable Recruiting 1 35 Months 616 Betty Raman, MBBS, DPhil, FRAC, Betty Raman, MBBS, DPhil, FRACP, Betty Raman, MBBS, FRACP, DPhil, Mark Cassar, MBBS, Stefan Neubauer, MD, FMedSCi 2020-08-19
A clinical study to assess AR-701 in the treatment of patients with COVID-19 Coronavirus disease 19 infection AR-701 alone COVID19 Spike glycoprotein inhibitor Aridis Pharmaceuticals Inc Phase Not Applicable Planned 0 2020-08-14
CT Abnormalities Evocative of Lung Infection Are Associated With Lower 18F-FDG Uptake in Confirmed COVID-19 Patients Coronavirus disease 19 infection, Lung infection 18F-FDG alone, Vereos digital hybrid system (Philips) alone, computed tomography alone, positron emission tomography alone, viral testing alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Hospital, Nancy, France France 2020-03-15 2020-07-30 2020PI153, NCT04512118 Phase Not Applicable Completed 1 4 Months 22 Antoine VERGER 2020-08-18
Dysphagia Management During COVID-19 Pandemic Coronavirus disease 19 infection, Dysphagia Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Hacettepe University Turkey 2020-08-20 2020-11-30 DYSPHAGIA DURING COVID-19, NCT04509752 Phase Not Applicable Not yet recruiting 1 3 Months 50 NUMAN DEMİR, SELEN SEREL ARSLAN 2020-08-17
Parental Attitude Toward Children Dental Treatment During COVID-19 Pandemic Coronavirus disease 19 infection, Tooth disease Cairo University Egypt 2020-06-15 2020-06-25 COVID -19 AND DENTAL VISIT, NCT04512300 Phase Not Applicable Completed 1 267 Yasmin Mohamed 2020-08-16
Phase I/II Trial of Povidone-iodine (PVP-I) Nasal Swab For Preventing COVID-19 Spread in Healthy Subjects Coronavirus disease 19 infection povidone-iodine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Brigham & Women's Hospital 3M Co US 2020-08-31 2021-04-30 2020P002323, NCT04510402 Phase 1/Phase 2 Clinical Not yet recruiting 1 8 Months 50 Mark D Hornstein, MD, Raymond M Anchan, MD, PhD, Raymond Manohar Anchan, M.D.,Ph.D. 2020-08-17
Multicenter, randomized, double-blind, placebo-controlled, parallel group study evaluating the efficacy, reactogenicity and safety of the Ad5-nCoV recombinant vaccine against novel coronavirus infection in adult volunteers Coronavirus disease 19 infection Ad5-nCoV alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted CanSino Biologics Inc, NPO Petrovax Pharm LLC Saudi Arabia, Chile, Russian Federation, Brazil 2020-08-14 2021-07-31 Prometheus_Rus Phase 3 Clinical Not yet recruiting 11 11 Months 5000 2020-08-24
CHARTER-Irl: Nebulized Heparin to Reduce COVID-19 Induced Acute Lung Injury Acute lung injury, Coronavirus disease 19 infection nebulized unfractionated heparin alone, standard care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University College Galway Ireland 2020-09-30 2022-01-31 CHARTER-Irl, NCT04511923, NUIG-2020-003 Phase 1/Phase 2 Clinical Not yet recruiting 1 16 Months 40 David Cosgrave, John Laffey 2020-08-16
Transparent Elastomeric Respirator for Aerosol-based Protection Coronavirus disease 19 infection reusable elastomeric respirator with dual N95 filter alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Brigham & Women's Hospital Massachusetts General Hospital, Memorial Sloan-Kettering Cancer Center US 2020-07-25 2020-12-31 2020P000852, NCT04511390 Phase Not Applicable Recruiting 3 5 Months 100 C. Giovanni Traverso, Giovanni Traverso, MB, BChir, PhD, Manish Gala, MD, Paul Zel 2020-08-17
LOSVID: Losmapimod Safety and Efficacy in COVID-19 Coronavirus disease 19 infection, Inflammatory disease, Respiratory failure losmapimod alone, standard of care alone Double homeobox protein 4 inhibitor, p38 MAP kinase alpha inhibitor, p38 MAP kinase beta inhibitor, p38 MAP kinase inhibitor Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fulcrum Therapeutics Inc US, Mexico, Brazil 2020-08-31 2020-11-30 FIS-001-2020, LOSVID, NCT04511819 Phase 3 Clinical Recruiting 10 3 Months 410 Call Center, Daniela Pereira Mendes, David Rubio, MD, Diego Cadavid, MD, Folusakin Ayoade, MD, Iram Abbasi, Jose' Flores, MD, Karel Calero, MD, Natiana Nalin Vizioli, Rayo Morfin, MD, Rebecca Zash, MD, Rosie Magallon, Veronica Martin 2020-08-19
Feasibility, of Tele-rehabilitation Following COVID-19 Coronavirus disease 19 infection, Dyspnea Tele-pulmonary rehabilitation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hull University Teaching Hospitals NHS Trust UK 2020-08-12 2022-01-20 285205, NCT04511962 Phase 3 Clinical Not yet recruiting 1 17 Months 40 Angela Green, PhD, Caroline e Wright, BSc, Michael Crooks, MRCP, Michael Crooks, MRCP/MD, Michael f Crooks, MRCP 2020-08-16
RESCUE: A Study to Evaluate the Safety and Efficacy of Razuprotafib, a Novel Tie 2 Activator, in Hospitalized Subjects With Moderate to Severe Coronavirus Disease 2019 (COVID-19) Coronavirus disease 19 infection razuprotafib alone Protein tyrosine phosphatase beta inhibitor, Tek tyrosine kinase receptor stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Aerpio Therapeutics Inc Medical Technology Enterprise Consortium 2020-09-30 2021-02-28 AKB-9778-CI-6001, NCT04511650, RESCUE Phase 2 Clinical Not yet recruiting 0 5 Months 180 Ashley Best, PhD 2020-08-18
Bicalutamide to Block TMPRSS2 in Males With COVID-19 Infection Coronavirus disease 19 infection bicalutamide alone Androgen receptor antagonist Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Florida US 2020-09-30 2022-09-30 IRB202001669-A, NCT04509999, OCR38162 Phase 3 Clinical Not yet recruiting 1 24 Months 100 Elizabeth Piantadosi, Frederic Kaye, MD 2020-08-24
Evaluation of the effectiveness of hydroxychloroquine and clarithromycin in dyspnea and cough caused by COVID-19 in recovery phase Coronavirus disease 19 infection, Cough, Dyspnea clarithromycin (Tehran shimi company) alone, hydroxychloroquine (Rooz daroo company) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Iran University of Medical Sciences Iran 2020-08-22 IR.IUMS.FMD.REC.1399.244, IRCT20200718048129N1 Phase 3 Clinical Recruiting 1 45 Dr Sima Bahrami, Dr. Seyed Abbas Motavlian, Sima Bahrami 2020-08-24
Helmet versus Face Mask in Patients With Acute Respiratory Distress Syndrome Coronavirus disease 19 infection, Respiratory distress syndrome non invasive ventilation via helmet alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hamad Medical Corp Qatar 2020-08-31 2021-08-31 MRC-01-20-616, NCT04507802 Phase Not Applicable Not yet recruiting 1 12 Months 60 Abdulqadir J Nashwan, MSc, Abdulqadir J. Nashwan, MSc, Ahmed A Soliman, BSc, Ahmed S Mohamed, BSc, Ahmed S. Mohamed, BSc, Dore C Ananthegowda, MD, Hani S Elzeer, MD, Karimulla S Shaik, MD, Mohamad Y Khatib, MD, Mohamed Z Peediyakkal, MD, Moustafa S Elshafei, MD, Muhsen A Shahen, MD, Nevin Kannappilly, MD, Wael I Abdaljawad, MD 2020-08-17
Evaluating the effectiveness of intravenous ozonized saline in COVID-19 disease Coronavirus disease 19 infection Medozon device alone, Variable regimens including IFN beta-1a , IFN beta-1b , atazanavir + ritonavir , chloroquine phosphate , dexamethasone , enoxaparin sodium , heparin , hydroxychloroquine , lopinavir + ritonavir , ozonized saline HIV protease inhibitor, Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ahvaz University of Medical Sciences Iran 2020-08-22 IR.AJUMS.REC.1399.363, IRCT20200730048253N1 Phase 3 Clinical Recruiting 1 60 Dr. mohammad Badavi, Dr.Najme dareini, Najme dareini, Shokrollah Salmanzadeh Ramhormozi 2020-08-24
ONCOVID-21: Evaluation of a ddPCR Technology for the SARS-CoV-2 Detection in Symptomatic Patients With Suspicion of COVID-19 Coronavirus disease 19 infection Bio-Rad SARS-CoV-2 ddPCR Test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Leon Berard France 2020-09-30 2021-03-31 NCT04510454, ONCOVID-21, ONCOVID-21 - ET20-118 Phase Not Applicable Not yet recruiting 1 6 Months 200 Bénédicte MASTROIANNI, MD, Ellen BLANC 2020-08-19
Profile of hospitalized patients with Covid-19 and repercussions of physiotherapy Coronavirus disease 19 infection physiotherapy alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo Brazil 2020-06-18 33351020.2.0000.0068, 4.091.795, 4.172.084, RBR-2f9k8p, U1111-1255-6608 Phase Not Applicable Recruiting 1 2000 Clarice Tanaka 2020-08-14
A survey to analyze the understanding about the use of face mask among the general public during COVID 19 Coronavirus disease 19 infection face mask alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Kasturba Medical College and Hospital India 2020-08-20 CTRI/2020/08/027046 Phase Not Applicable Not yet recruiting 1 697 Dr Ranita Ghosh Dastidar, Dr Vaishali K 2020-08-24
Nursing students perception of out of the classroom learning during the period of COVID-19 Coronavirus disease 19 infection Adolescents (13-17 yrs), Young Adults (18-44 yrs) Manipal College of Nursing India 2020-08-31 CTRI/2020/08/027047 Phase Not Applicable Not yet recruiting 1 380 Linu Sara George, Prima Jenevive Jyothi DSouza 2020-08-14
Yoga for Police personnel Coronavirus disease 19 infection Pranayama and Yoga Nidra alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Sri Devaraj Urs Academy of Higher Education and Research India 2020-08-17 CTRI/2020/08/027048 Phase 3 Clinical Not yet recruiting 1 60 Dr Patil NJ 2020-08-14
Effect of hemoperfusion on short-term outcome of critical ill COVID-19 Acute stress disorder, Coronavirus disease 19 infection, Delirium ABCDE protocol alone, CytoSorb filter alone, anticoagulant therapy alone, antiviral therapy alone, blood sugar management alone, complementary medication therapy alone, corticosteroid therapy alone, face mask alone, hemoperfusion therapy alone, heparin alone, low tidal volume ventilation alone, non-invasive mechanical ventilation alone, proton pump inhibitor therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Tabriz University of Medical Sciences Iran 2020-08-22 IR.TBZMED.REC.1399.493, IRCT20091012002582N22 Phase 3 Clinical Recruiting 1 160 Ata Mahmoodpoor, Dr. khosro Adibkia, Mojtaba Mohammadzadeh 2020-08-24
Study of families who travelled from another place and had COVID-19 Coronavirus disease 19 infection Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Dr TMA Pai Hospital India 2020-08-20 CTRI/2020/08/027049 Phase Not Applicable Not yet recruiting 1 19 Shashikiran Umakanth 2020-08-17
PPE Study: Assessment of PPE usage pattern and the associated Surgeon Discomfort and Fatigue Study Coronavirus disease 19 infection, Fatigue Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Tata Memorial Centre India 2020-08-20 CTRI/2020/08/027050, PPE Study Phase Not Applicable Not yet recruiting 1 500 DrShivakumar Thiagarajan 2020-08-14
Survey of challenges faced by pain and palliative physicians working in cancer set up during corona virus disease time Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Medical Sciences India 2020-08-10 CTRI/2020/08/027051 Phase Not Applicable Not yet recruiting 1 200 Dr Seema Mishra 2020-08-14
Evaluation of the effect of curcumin in improving patients with covid -19 Coronavirus disease 19 infection curcumin-piperine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Bandare-abbas University of Medical Sciences Iran 2020-08-05 IR.HUMS.REC.1399.187, IRCT20200514047445N1 Phase 3 Clinical No longer recruiting 1 60 Majid Teremmahi Ardestani, Timur Agha Molai 2020-08-24
A trial to evaluate OraCOV for the prevention of COVID-19 Coronavirus disease 19 infection OraCOV alone covidX Germany Phase Not Applicable Planned 1 2020-08-18
GlobalSurg-CovidSurg Week Coronavirus disease 19 infection surgery alone The University of Birmingham Association of Coloproctology of Great Britain and Ireland, Bowel Disease Research Foundation of ACPGBI, Bowel and Cancer Research, British Association of Surgical Oncology: Breast Group, British Gynaecological Cancer Society, European Society of Coloproctology, NIHR Academy, National Institute for Health Research (NIHR), Sarcoma UK, Vascular Society for Great Britain and Ireland, Yorkshire Cancer Research UK 2020-10-01 2020-12-01 GS-CSWEEK.20200713, NCT04509986 Phase Not Applicable Not yet recruiting 1 2 Months 1000 Aneel Bhangu, PhD, Dmitri Nepogodiev, Master 2020-08-18
Virtual Teaching Kitchen Coronavirus disease 19 infection, Metabolic syndrome X Virtual Nutritional Education alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Boston University US 2020-09-30 2021-06-30 H-39597, NCT04509206 Phase Not Applicable Not yet recruiting 1 9 Months 25 Iniya Rajendran, Naomi M Hamburg, MD 2020-08-19
KAND-567 Versus Placebo in Subjects Hospitalized with COVID-19. A Phase II, Randomized, two-Arm, Parallel-Group, Double-blind Study to Evaluate Efficacy, Safety, Tolerability, and Pharmacokinetics Coronavirus disease 19 infection KAND-567 alone, best standard treatment alone CX3CR1 chemokine antagonist, Fractalkine ligand inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kancera AB Capio S:t Görans Hospital, Scandinavian CRO, Scandinavian Development Services AB, Science For Life Laboratory Sweden 2020-07-02 2020-002322-85, KAN0006 Phase 2 Clinical Recruiting 1 40 Anna Runeson 2020-08-14
Effect of erythropoietin on COVID-19 Coronavirus disease 19 infection, Hypoxia, Lung disease, Lymphocytopenia, Tachypnea Variable regimens including atazanavir , atazanavir + ritonavir , chloroquine phosphate , enoxaparin sodium , epoetin alfa (Procrit/Eprex), Johnson & Johnson , hydroxychloroquine sulfate , lopinavir + ritonavir Erythropoietin ligand, HIV GAG POL polyprotein inhibitor, HIV GAG protein inhibitor, HIV protease inhibitor, HIV-1 protease inhibitor, Low molecular weight heparin Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Bandare-abbas University of Medical Sciences Iran 2020-06-21 IR.HUMS.REC.1399.165, IRCT20200509047364N1 Phase 2 Clinical Recruiting 1 20 Dariush Hooshyar, Dr. Mehdi Hassaniazad, Dr. Mitra Kazemijahromi, Dr. Teamur Aghamolaei 2020-08-18
Evaluation of the effect of shallomin on the treatment and improvement of symptoms in patients with Covid 19 Coronavirus disease 19 infection, Respiratory disease approved COVID19 protocol treatment alone, shallomin (Sadra Noor Biotechnology Pharmaceutical Company) alone Dezful University of Medical Sciences Iran 2020-08-10 IR.DUMS.REC.1399.014, IRCT20200725048199N1 Phase 2 Clinical Recruiting 1 146 Mahnaz Nosratabadi, Maysam Mardsoltani, mahnaz nosratabadi 2020-08-18
ARBS CORONA I: Host-Response Mediators in Coronavirus (COVID-19) Infection Coronavirus disease 19 infection angiotensin II type 1 receptor blocker therapy alone, angiotensin-converting enzyme inhibitor therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of British Columbia British Columbia Centre for Disease Control, Canadian Institutes of Health Research, McGill University Health Center, Peking Union Medical College Hospital, Research Institute of the McGill University Health Centre, University of Alberta, University of Calgary, University of Ottawa, University of Pennsylvania, University of Toronto, University of Victoria, Wuhan University Canada 2020-03-17 2022-06-30 ARBS CORONA I, H20-00600, NCT04510623 Phase Not Applicable Recruiting 15 27 Months 500 Allison McGeer, MD, Ari Joffe, MD, Brent Winston, MD, David Maslove, MD, David Sweet, MD, Francois Lamontagne, MD, Gregory Haljan, MD, James A Russell, MD, Jim Russell, John Marshall, MD, Lynda Lazosky, Matthew Cheng, MD, Nataly Farshait, Oleksa Rewa, MD, Puneet Mann, MSc, Robert Fowler, MD, Todd Lee, MD 2020-08-14
Canine COVID-19 Detection Coronavirus disease 19 infection traditional sniffer dog medical-detection alone Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Arthropod Control Product Test Center (ARCTEC) Cardiff University, Medical Detection Dogs, University of Durham UK 2020-07-02 2020-10-31 LSH1285, NCT04509713 Phase 1 Clinical Recruiting 1 3 Months 16250 James Logan, James Logan, PHD 2020-08-14
A phase III clinical trial of Brexanolone in patients with advanced COVID-19 related acute respiratory distress syndrome (ARDS) Coronavirus disease 19 infection, Respiratory distress syndrome brexanolone alone GABA A receptor modulator SAGE Therapeutics Inc 2020-12-31 Phase 3 Clinical Planned 0 2020-08-13
COVIDSTEROID2: Higher Versus Lower Doses of Dexamethasone for COVID-19 and Severe Hypoxia Coronavirus disease 19 infection, Hypoxia betamethasone alone, dexamethasone (Dexavit) alone, standard care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Scandinavian Critical Care Trials Group Aalborg Universitetshospital, Aarhus University Hospital, Centre for Research in Intensive Care (CRIC), Copenhagen Trial Unit, Rigshospitalet, Denmark, The George Institute for International Health Switzerland, Sweden, India, Denmark 2020-08-17 2022-02-17 2020-003363-25, 2020-07-16, COVIDSTEROID2, H-20051056, NCT04509973, RH-ITA-009 Phase 3 Clinical Not yet recruiting 51 18 Months 1000 Amit Shobhavat, Anders Møller, Anders Perner, MD PhD, Anders Perner, MD, PhD, Professor, Andreas Wiklund, Anna Nilsson, Anne Sofie Andreasen, Bharath KT Vijayaraghavan, Binila Chacko, Buster Mannheimer, Carl-Johan Treutiger, Farhad Kapadia, Fredrik Schiöler, Fredrik Sjövall, Iben S Darfelt, J V Divatia, Jacob Hollenberg, Jonathan Oras, Kapil Boraoke, Kedar Toraskar, Magnus Gisslen, Magnus Hedenstierna, Margit Smitt, MD, Marie Warrer B Petersen, MD, Marie Warrer Petersen, MD, Michelle Chew, Neeta B Nayak, Olof Wall, Omender Singh, Pontus Naucler, Pravin Amin, Rajesh Chawla, Saif M Khan, Sanjith Saseedharan, Sara Tehrani, Syed M Ahmed, Thomas Mohr, Urvi Shukla, Vibeke RL Jørgensen, MD, PhD, Zubair U Mohamed, Åke Norberg 2020-08-14
Ivermectin Nasal Spray for COVID-19 Patients Coronavirus disease 19 infection ivermectin alone, standard care alone Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Tanta University Egypt 2020-09-30 2020-12-31 IVRINH, NCT04510233 Phase 2 Clinical Not yet recruiting 1 3 Months 60 Kamal Okasha, PhD, Nahla El-Ashmawy, PhD 2020-08-14
Characterizing the Immune Response and Neuronal Damage in COVID-19 Coronavirus disease 19 infection, Inflammatory disease, Nerve injury Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Inselspital, Berne University of Bern Switzerland 2020-03-05 2021-03-05 NCOV19, NCT04510012 Phase Not Applicable Recruiting 1 12 Months 150 Cédric Hirzel, MD, Denis Grandgirard, PhD, Franziska Suter, PhD, Jörg C Schefold, MD, Leib L Stephen, MD, Ronald Dijkman, PhD, Thibaud Spinetti, PhD 2020-08-14
COVID SAFE: COVID-19 SAFE Enrollment Coronavirus disease 19 infection Opt-in Recruitment Email alone, Opt-out Recruitment Email alone, saliva-based viral testing alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Pennsylvania US 2020-08-31 2020-10-31 843565, COVID SAFE, NCT04506268 Phase Not Applicable Not yet recruiting 1 2 Months 1200 Chalanda N Evans, BS, Mitesh S Patel, MD 2020-08-18
RAAS-COVID: The McGill RAAS-COVID-19 Trial Coronavirus disease 19 infection, Viral pneumonia anti-hypertensive medication alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Research Institute of the McGill University Health Centre McGill University Health Center, Sir Mortimer B Davis Jewish General Hospital, Université De Lorraine Canada 2020-09-01 2021-09-01 MP-37-2021-6614, NCT04508985, RAAS-COVID Phase Not Applicable Not yet recruiting 1 12 Months 40 Abhinav Sharma, MD, Julie Lebel, PM 2020-08-21
Technology-assisted Index on Improving Hand Hygiene of Registered Nurses Coronavirus disease 19 infection 3M Clean-Trace Surface ATP test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Taiwan University Hospital Taiwan 2020-08-31 2022-05-31 202006019RINB, NCT04508114 Phase Not Applicable Not yet recruiting 1 21 Months 120 Man-Rong Hsu, BSN, Wei-Wen Wu, PhD 2020-08-13
CoviDep: Treatment of Depressive Symptoms in Older Individuals in Isolation During Covid-19 Coronavirus disease 19 infection, Depression Brief Behavioral Activation with Mental Imagery alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) Uppsala University Vastmanland County Council (Landstinget) Sweden 2020-08-17 2021-07-31 2020-02079, CoviDep, NCT04508868 Phase Not Applicable Recruiting 1 11 Months 154 Johnny Pellas, MSc, Mattias Damberg, MD, PhD 2020-08-20
COVID-19 GDI: COVID-19 Germ Defence: a website to improve infection control during the COVID-19 pandemic Coronavirus disease 19 infection, Influenza virus infection, Respiratory tract infection COVID-19 Germ Defence website alone, digital behavioral change intervention alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Bristol NIHR Health Protection Research Unit (HPRU) in Behavioural Science and Evaluation, National Institute for Health Research, Applied Research Collaboration West (NIHR ARC West), United Kingdom Research & Innovation UK 2020-03-30 2021-04-30 COVID-19 GDI, CPMS 46740, IRAS 287978, ISRCTN14602359, UKRI (MRC) MC_PC_19068, UOB 2020-3213 Phase Not Applicable Not yet recruiting 15 13 Months 6822 Dr Jeremy Horwood, Dr Melanie Chalder 2020-08-13
OMA-COVID-19: Effect of the anti-inflammatory test drug anakinra in patients with coronavirus (COVID-19) requiring oxygen support Coronavirus disease 19 infection, Inflammatory disease, Respiratory distress syndrome, Viral pneumonia anakinra alone Type I IL-1 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sultan Qaboos University Oman 2020-05-25 2020-08-15 ISRCTN74727214, OMA-COVID-19 Phase 2 Clinical Completed 2 2 Months 75 Dr Balkhair 2020-08-18
Japan COVID-19 Study of the psychosocial impacts of the postponement/cancellation of reproductive medicine Acute stress disorder, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dokkyo Medical University, Saitama Medical Center, Japan Japan Society for Reproductive Psychology Japan 2020-08-17 UMIN000041387 Phase Not Applicable Not yet recruiting 1 1100 Kouhei Sugimoto, Tomoe Koizumi 2020-08-14
COVER: Randomized, Double-blind, Multi Centre Phase II, Dose Finding Clinical Trial on Ivermectin for the early Treatment of COVID-19 Studio clinico randomizzato, in doppio cieco, multicentrico, di fase II, per l'individuazione del dosaggio di impiego dell'Ivermectina per il trattamento precoce del COVID-19 Coronavirus disease 19 infection ivermectin alone Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ospedale Sacro Cuore don Calabria Italy 2020-06-12 2020-002283-32, 2020-34, COVER Phase 2 Clinical Recruiting 1 122 Unità per la Ricerca Clinica 2020-08-15
Camphora in COVID: A clinical study to evaluate efficacy and safety of Camphora tablets in Covid positive patients Coronavirus disease 19 infection Camphora alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) TNMC and BYL Nair Hospital India 2020-08-17 CTRI/2020/08/027045, Camphora in COVID Phase 2 Clinical Not yet recruiting 1 300 Dr Ashish Agarwal, Dr Renuka Munshi 2020-08-17
Performance Assessment of SARS-CoV-2 Detection Breath Biopsy - SARS-CoV-2 Study (COVID) Coronavirus disease 19 infection breath biopsy face masks with removable filters and fitted PVA strip alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Owlstone Nanotech Inc Onze Lieve Vrouwe Gasthuis Amsterdam, Universiteit Maastricht 2020-08-31 2020-12-31 NCT04508556, SARS-COV-2 STUDY Phase Not Applicable Not yet recruiting 0 4 Months 500 Alexandra DeSaedeleer, Amerjit kang, Paul Bresser, Paul Savelkoul, 2020-08-13
To observe the outcome of Classical Ayurvedic medicine for the treatment of COVID-19 Coronavirus disease 19 infection Maha-Sudarshana Ghan Vati alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Shri Krishna Ayush University India 2020-08-14 CTRI/2020/08/027044 Phase 2/Phase 3 Clinical Not yet recruiting 1 100 Professor Dr Anil Sharma, Professor Dr Ashish Mehta, Professor Dr Baldev Kumar 2020-08-13
COREG: The McMaster Multi-Regional COVID-19 Hospital Case Registry Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) McMaster University Canadian Institutes of Health Research, Grand River Hospital, Hamilton Academic Health Sciences Organization, Hamilton Health Sciences Corp, Niagara Health System, St Josephs Healthcare Hamilton, St. Mary’s General Hospital Canada 2020-04-15 2021-07-31 172754, COREG, NCT04508959 Phase Not Applicable Recruiting 4 15 Months 1500 Andrew P Costa, PhD, Darly Dash, MSc, Jessica Kapralik, MD (PGY5), Marla Beauchamp, PhD, Mats L Junek, MD, MSc, MyLinh Duong, MBBS, MSc, FRACP, Rebecca J Kruisselbrink, MD, MPH, FRCPC, Terence Ho, MD, FRCP, Tyler Pitre, MA, MD (PGIM) 2020-08-13
PREVENT-HD: A Study of Rivaroxaban to Reduce the Risk of Major Venous and Arterial Thrombotic Events, Hospitalization and Death in Medically Ill Outpatients With Acute, Symptomatic Coronavirus Disease 2019 (COVID-19) Infection Cerebrovascular disease, Coronary artery disease, Coronavirus disease 19 infection, Ischemic stroke, Peripheral vascular disease, Thromboembolism rivaroxaban alone, standard of care alone Factor Xa antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Janssen Research & Development LLC US 2020-08-12 2021-04-06 39039039DVT3004, CR108849, NCT04508023, PREVENT-HD Phase 3 Clinical Not yet recruiting 3 7 Months 4000 Study Contact 2020-08-13
A clinical trial of eravacycline for potential treatment of SARS-CoV-2 infection (COVID-19) Coronavirus disease 19 infection repurposed eravacycline (COVID-19), SOM Biotech alone COVID19 replicase polyprotein 1a inhibitor, COVID19 replicase polyprotein 1ab inhibitor, Viral protease inhibitor SOM Biotech SL US, Europe Phase Not Applicable Planned 1 2020-08-12
Study to Evaluate the Safety, Tolerability and Pharmacokinetics of AZD-7442 in Healthy Adults Coronavirus disease 19 infection AZD-7442 alone COVID19 Spike glycoprotein inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) AstraZeneca plc Biomedical Advanced Research and Development Authority (BARDA), Defense Advanced Research Projects Agency, PAREXEL International, US Department of Defense, US Department of Health and Human Services UK 2020-08-17 2021-09-14 D8850C00001, NCT04507256 Phase 1 Clinical Recruiting 1 12 Months 48 AstraZeneca Clinical Study Information Center, Muna Albayaty, MBChB, FFPM, MSc 2020-08-27
Electronic Stethoscope Use During Intubation in Full Personal Protective Equipment Coronavirus disease 19 infection, Surgical procedure auscultation alone, electronic stethoscope alone, endobronchial blocker alone, endotracheal tube alone, fiberscope alone, general anesthesia alone, traditional stethoscope alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Taiwan University Hospital Taiwan 2020-08-14 2021-07-31 202005104RINC, NCT04507958 Phase Not Applicable Not yet recruiting 1 11 Months 80 Chun-Yu Wu, PhD 2020-08-14
Online meditation as an aid in reducing symptoms of Depression, Anxiety and Psychological Stress in Resident Physicians during COVID-19 pandemic in Brazil Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression on-line meetings for meditation training alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) University of Sao Paulo Brazil 2020-07-20 2020-09-30 33585620.0.0000.0045, 4.129.324, RBR-2w7ghc, U1111-1255-3186 Phase Not Applicable Recruiting 1 2 Months 44 Maria do Rosário Toscano von Flach 2020-08-24
A Survey to Assess Effects of Covid-19 on Cardiovascular Patients Cardiac failure, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centro en Insuficiencia Cardiaca Fundación Clínica Médica Sur, Instituto Nacional de Cardiologia Ignacio Chavez Mexico 2019-05-15 2021-07-15 20-1156, NCT04508920 Phase Not Applicable Recruiting 1 26 Months 76 ALAN FUENTES, MD, ALAN FUENTES-MENDOZA, MD, CHUQUIURE-VALENZUELA EDUARDO, MD, MSc, EDUARDO CHUQUIURE-VALENZUELA, MD, EDUARDO CHUQUIURE-VALENZUELA, MD MSc 2020-08-13
COVID SAFE: COVID-19 Screening Assessment for Exposure Coronavirus disease 19 infection saliva-based testing alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Pennsylvania US 2020-08-31 2021-03-31 843565-OBS, COVID SAFE, NCT04508777 Phase Not Applicable Not yet recruiting 1 7 Months 600 Chalanda N Evans, BS, Mitesh S Patel, MD 2020-08-14
Effect of the Use of Anticoagulant Therapy During Hospitalization and Discharge in Patients With COVID-19 Infection Coronavirus disease 19 infection enoxaparin sodium alone Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Regional de Alta Especialidad de Ixtapaluca Mexico 2020-06-20 2020-12-30 NCT04508439, NR-CEI-HRAEI-19-2020 Phase 2 Clinical Recruiting 1 6 Months 130 Omar O Ramos-Peñafiel, Omar Ramos-Peñafiel, Omar Ramos-Peñafiel, MD, PhD 2020-08-13
A clinical study to assess IgG1 Ab1 for the potential treatment of SARS-CoV-2 infection Coronavirus disease 19 infection IgG1 Ab1(COVID-19 infection) Abound bio/Saudivax alone University of Pittsburgh Medical Center Phase Not Applicable Planned 0 2020-08-12
Long-term Outcomes in Patients With COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Renji Hospital China 2020-08-10 2021-08-31 COVID-19 PROGNOSIS, NCT04508712 Phase Not Applicable Not yet recruiting 1 12 Months 900 Diansan Su, MD,PhD, Weifeng Yu, MD,PhD 2020-08-20
COVID-19 Associated Coagulopathy in Egypt Blood clotting disorder, Coronavirus disease 19 infection Assiut University Egypt 2020-08-07 2020-10-31 17300413, NCT04507230 Phase Not Applicable Recruiting 1 2 Months 100 Azza Abdelaal, MD, PhD, Azza Ezzeldin, MD,PhD, Hanan Galal, MD, PhD 2020-08-13
MITIGATE COVID-19: A Pragmatic, Randomized Trial of Icosapent Ethyl for High-Cardiovascular Risk Adults in the Era of Coronavirus Disease 2019 Atherosclerosis, Coronavirus disease 19 infection, Influenza virus infection, Ischemic stroke, Myocardial infarction, Peripheral vascular disease, Upper respiratory tract infection icosapent ethyl, Amarin alone Apolipoprotein B antagonist, Phospholipase A2 inhibitor Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kaiser Permanente Amarin Corp plc US 2020-08-07 2023-02-28 1597940, MITIGATE COVID-19, NCT04505098 Phase 4 Clinical Recruiting 1 30 Months 16500 Alan Go, MD, Alan S Go, M.D., Andrew Ambrosy, M.D., Andrew P Ambrosy, M.D. 2020-08-14
The C3I COVID-19 Project Coronavirus disease 19 infection, Dyspnea, Viral pneumonia University of Wisconsin-Madison National Cancer Institute US 2020-08-10 2021-12-31 2020-069, A534253, CTRI, NCT04506528, OISE-20-66590-1, SMPH/MEDICINE Phase Not Applicable Recruiting 25 16 Months 170000 Amy Conlon, MPH, Betsy Rolland, PhD, MLIS, MPH, Michael C Fiore, MD, MPH, MBA, Rob Adsit, MEd, Stevens S Smith, PhD, Tanya R Schlam, PhD 2020-08-13
EXPLORE COVID-19: An exploratory translational research study to analyze the immune response of COVID-19 patients at varying stages of disease Coronavirus disease 19 infection Innate Pharma SA Assistance Publique Hopitaux De Marseille, Hôpital de la Timone (UPCET/CIC) EXPLORE COVID-19 Phase Not Applicable Status not specified 0 2020-08-12
COVRehab: The Usability, Feasibility and Tolerability of Virtual Reality for Rehabilitation From COVID-19 Cognitive disorder, Coronavirus disease 19 infection, Psychiatric disorder cognitive rehabilitation alone, physical rehabilitation alone, psychological rehabilitation alone, standard physiotherapy alone, virtual reality headset rehabilitation alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Radboud University Netherlands 2020-08-01 2021-01-01 COVREHAB, COVRehab, NCT04505761 Phase Not Applicable Recruiting 1 5 Months 40 Bart Staal, PT, PhD, Harry van Goor, MD, PhD, Merlijn Smits, MSc, Merlijn Smits, Msc 2020-08-25
Effect of a Nss to Reduce Complications in Patients With Covid-19 and Comorbidities in Stage III Coronavirus disease 19 infection, Respiratory distress syndrome macronutrient intake alone, nutritional support system alone, standard diet alone, Variable regimens including Cyanomax Ultra , L-arginine , Neurobion , Saccharomyces Bourllardii , Spirulina Maxima , ascorbic acid , cholecalciferol , folic acid , glutamine , magnesium , omega 3 fatty acid , resveratrol , selenium , zinc Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Anahuac University Mexico 2020-08-31 2020-12-31 202036, NCT04507867 Phase Not Applicable Not yet recruiting 1 4 Months 240 Fernado Leal Martínez, Ph.D, Fernando Leal Martínez, Ph.D 2020-08-17
Efficacy, Safety and Immunogenicity Study of SARS-CoV-2 Inactivated Vaccine (COVID-19) Coronavirus disease 19 infection CoronaVac alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Bio Farma National Institute Of Health Research & Development (Nihrd)- Ministry Of Health Of The Republic Of Indonesia, Sinovac Life Sciences Co., Ltd., Universitas Padjadjaran Indonesia 2020-08-10 2021-09-30 COV2-0320, NCT04508075 Phase 3 Clinical Recruiting 1 13 Months 1620 Eddy Fadlyana, MD, PhD, Novilia Sjafri Bachtiar, MD, PhD, Prof Kusnandi Rusmil, MD, PhD, Prof. Kusnandi Rusmil, MD, PhD 2020-08-24
Comparison of Extra Vascular Lung Water Index in Covid-19 ARDS and 'Typical' ARDS Patients Coronavirus disease 19 infection, Respiratory distress syndrome transpulmonary thermodilution (TPTD) technique alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Istanbul University-Cerrahpasa Turkey 2020-09-01 2020-12-31 0308202247, NCT04508933 Phase Not Applicable Not yet recruiting 1 4 Months 10 Olcay Dilken, MD, Yalım Dikmen, Prof 2020-08-13
VOICE-COVID: The VOICE-COVID-19 Coronavirus disease 19 infection Alexa (Amazon) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) McGill University Health Center, Research Institute of the McGill University Health Centre Amazon Web Services Canada 2020-07-01 2020-11-01 2020-6583, NCT04508972, VOICE-COVID Phase Not Applicable Recruiting 1 4 Months 200 Abhinav Sharma, MD, Abhinav h Sharma, MD, Julie Lebel 2020-08-20
Eosinophil and Anticoagulation in COVID-19 Patients Coronavirus disease 19 infection low molecular weight heparin alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bursa Postgraduate Hospital Turkey 2020-05-15 2020-07-15 BURSA POSTGRADUATE HOSPITAL, NCT04507282 Phase Not Applicable Completed 1 2 Months 80 Hasan ARI 2020-08-19
Mesenchymal Stem Cell Therapy For Covid 19 Coronavirus disease 19 infection, Viral pneumonia mesenchymal stem cells therapy alone, standard care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Neurogen Brain and Spine Institute, Reelabs Private Ltd India 2020-08-10 CT-06/2020, CTRI/2020/08/027043 Phase 1 Clinical Not yet recruiting 1 20 Dr Abhijit Bopardikar, Dr Alok Sharma, Dr Rohit Kulkarni 2020-08-13
Comparison Between Positive and Negative COVID-19 Pneumonia Coronavirus disease 19 infection, Respiratory disease, Viral pneumonia PCR assay alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Palermo Italy 2020-03-15 2020-12-01 ACPM26, NCT04507893 Phase Not Applicable Recruiting 3 8 Months 80 Antonio Carroccio, MD, Enzo M Farinella, MD, Giuseppe Arcoleo, MD, Pasquale Mansueto, Clinical Professor 2020-08-13
A compassionate-use study evaluating narsoplimab, Omeros investigational human monoclonal antibody targeting mannan-binding lectin-associated serine protease-2 (MASP-2), in the treatment of COVID-19 patients with Acute Respiratory Distress Syndrome (ARDS) Coronavirus disease 19 infection, Respiratory distress syndrome narsoplimab alone Complement cascade inhibitor, Mannan-binding lectin serine protease-2 inhibitor Middle-aged Adults (45-64 yrs) Omeros Corp Italy Phase Not Applicable Status not specified 1 Alessandro Rambald 2020-08-17
PSIMCOV: Psychological Impact of COVID-19 Pandemic in Healthcare Workers Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hospital General Universitario de Valencia Spain 2020-04-09 2020-04-30 COV2-2020, NCT04506515, PSIMCOV Phase Not Applicable Completed 1 3000 Carolina Soledad Romero Garcia, MD, PhD 2020-08-13
Anti-thrombotics for Adults Hospitalized With COVID-19 Coronavirus disease 19 infection Variable regimens including dalteparin sodium , enoxaparin sodium , heparin , tinzaparin sodium , unfractionated heparin Antithrombin III, Factor IIa antagonist, Factor Xa antagonist, Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Pittsburgh National Heart Lung and Blood Institute US 2020-08-31 2021-12-31 ACTIV-4 ACUTE, NCT04505774 Phase 4 Clinical Not yet recruiting 1 16 Months 2000 Judith Hochman, MD, Matthew Neal MD, Matthew Neal, MD 2020-08-14
Secondary attack rate of COVID-19, Kerala Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Government Medical College Kannur India 2020-09-01 CTRI/2020/08/027042 Phase Not Applicable Not yet recruiting 1 Anitha S S 2020-08-13
An Observational Study of Guduchi Extract Tablet Coronavirus disease 19 infection Guduchi extract tablet alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ministry of Ayush India 2020-08-15 CTRI/2020/08/027034 Phase Not Applicable Not yet recruiting 1 1200 Dr Sanjay Srivastava, Prof Dr Abhimanyu Kumar 2020-08-13
etrospective Analysis of 245 COVID-19 Cases from a Government Teaching Hospital of North India Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Superspeciality Pediatric hospital and Postgraduate Teaching Institute India 2020-08-19 CTRI/2020/08/027036 Phase Not Applicable Not yet recruiting 1 245 Dr Divya Jain 2020-08-13
Effect of yoga for COVID-19 patients in addition to regular treatment Coronavirus disease 19 infection pranayama yoga nidra alone, standard care alone, yoga alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Sri Devaraj Urs Academy of Higher Education and Research India 2020-08-17 CTRI/2020/08/027037 Phase 3 Clinical Not yet recruiting 1 60 Nitin Patil 2020-08-13
Study to assess effects of nano-ozonised hydrogen peroxide nebulization on results of RT-PCR for novel coronavirus thus infectivity and clinical course among mild to moderate sick COVID-19 patients Coronavirus disease 19 infection Triozone alone, nano-ozonised hydrogen peroxide nebulization alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Dr. S.N. Medical College, Jodhpur India 2020-08-20 CTRI/2020/08/027038 Phase 3 Clinical Not yet recruiting 1 Dr Ashish Gautam, Dr Prabhat Kumar Agrawal 2020-08-13
An interventional study to access the effect of ayurvedic medicine in positive cases of COVID-19 Coronavirus disease 19 infection Variable regimens including Lavangadi vati , Mahasudarshan ghana vati , Samsamani vati Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ministry of Ayush India 2020-08-12 CTRI/2020/08/027040 Phase 3 Clinical Not yet recruiting 2 200 Dr Bishnu Choudhury, Prof Dr Pradip Kumar Goswami 2020-08-13
Clinical Trial on COVID-19 Patients to Improve Immunity Coronavirus disease 19 infection herbivor syrup alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Venkat Pharma Ltd India 2020-08-14 CTRI/2020/08/027041, Herbovir/CT/2020 Version 1.0 Phase 4 Clinical Not yet recruiting 1 40 Dr A Gopal Rao, Sri H Srinivas 2020-08-13
Pilot Study to Assess Efficacy and Safety of Treamid in the Rehabilitation of Patients After COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia Treamid alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Pharmenterprises LLC Russian Federation 2020-08-31 2020-11-30 COVID-TRE-03, NCT04527354 Phase 2 Clinical Not yet recruiting 24 3 Months 60 Alexander Wiesel, MD, PhD, Prof., Bulat Bakirov, MD, PhD, Elena Smolyarchuk, MD, PhD, Evgeniy Bazdyrev, MD, PhD, Kirill Zykov, MD, PhD, Prof., Lilia Kozyreva, MD, PhD, Olga Barbarash, MD, PhD, Prof., Olga Magnitskaya, MD, PhD, Svetlana Berns, MD, PhD, Prof., Svetlana Ermolova, MD, Vladimir Yakusevich, MD, PhD, Prof., Yuri Schwartz, MD, PhD, Prof. 2020-08-27
ENSEMBLE: A Study of Ad26.COV2-S for the Prevention of SARS-CoV-2-Mediated COVID-19 in Adult Participants Coronavirus disease 19 infection JNJ-78436735 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Janssen Vaccines & Prevention BV, Johnson & Johnson Biomedical Advanced Research and Development Authority (BARDA), Burroughs Wellcome Inc, National Institutes of Health, The Ragon Institute Colombia, Mexico, US, Peru, Ukraine, Philippines, Chile, South Africa, Brazil 2020-09-05 2023-03-10 CR108876, ENSEMBLE, NCT04505722, VAC31518COV3001 Phase 3 Clinical Not yet recruiting 178 30 Months 60000 Janssen Vaccines & Prevention B.V. Clinical Trial, Study Contact 2020-08-16
COST-NHS: Burden for Staff Working in the NHS Coronavirus disease 19 infection, Psychiatric disorder Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sheffield Teaching Hospitals NHS Foundation Trust University of Sheffield UK 2020-06-02 2022-04-26 COST-NHS, NCT04506632, STH21373 Phase Not Applicable Recruiting 1 22 Months 100 Colette Mann, Loretta Chantry-Groves, Sarah Danson, Professor 2020-08-13
STOP-Coronavirus: Clinical, Immunological, Genomic, Virological and Bioethical Actors of COVID-19 Coronavirus disease 19 infection Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto de Investigación Sanitaria de la Fundacion Jimenez Diaz Fundacion De Investigacion Hospital 12 De Octubre, Hospital Universitario 12 de Octubre, Hospital Universitario Infanta Elena, Hospital Universitario Virgen de la Arrixa, Instituto Murciano de Investigación Biosanitaria Virgen de la Arrixaca, Jimenez Diaz Foundation Spain 2020-08-01 2021-08-01 COV20/00181, NCT04505709, STOP-CORONAVIRUS, STOP-Coronavirus Phase Not Applicable Recruiting 4 12 Months 1000 2020-08-12
LPSARS2: Study of a Possible Respiratory Degradation Prognosis Caused by Biomarkers in Severe Forms of COVID-19 Pneumonia Coronavirus disease 19 infection, Respiratory tract infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Groupe Hospitalier Paris Saint-Joseph Centre Hospitalier Victor Dupouy France 2020-05-14 2020-11-30 LPSARS2, LPSARS2, NCT04505605 Phase Not Applicable No longer recruiting 1 6 Months 200 2020-08-12
GenCov: Genetic Mechanisms Underlying SARS-CoV-2 Infection and the Impact of COVID-19 on Cognitive Function Coronavirus disease 19 infection Whole exome sequencing alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Texas Cardiac Arrhythmia Research Foundation US 2020-08-31 2021-09-30 GenCov, NCT04506229, TCAI_GENCOV Phase Not Applicable Recruiting 1 13 Months 60 Andrea Natale, Bryan MacDonald, Sanghamitra Mohanty 2020-08-27
SARS-COV-2 and COVID-19 - a randomized, controlled trial (unblinded) Coronavirus disease 19 infection Variable regimens including aadathodai manapagu , amukara chooranam , kabasura kudineer , muthu parpam , nilavembu kudineer , pavala parpam , seenthil chooranam , silasathu parpam , sivanar amirtham , swasakudori maathirai , thippili rasayanam , thoothuvalai legiyam Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Government Kilpauk Medical College India 2020-08-07 CTRI/2020/08/027033 Phase 2 Clinical Not yet recruiting 1 100 Dr A Shiyam ranjith, Dr N Anbu, Dr P Vasanthamani 2020-08-27
An Open Label Physician Initiated 28 Day Phase 2a Study Of Ifenprodil On Lung Function In Confirmed Covid-19 Infected Patients With Severe Pneumonia Coronavirus disease 19 infection, SARS coronavirus infection ifenprodil alone Noncompetitive NMDA antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dong-A University Hospital, NOVOTECH ASIA KOREA CO. LTD. Dong-A University Hospital South Korea 2020-09-30 AGN120-2, KCT0005307 Phase 2 Clinical Recruiting 3 40 Dong Sik Jung 2020-08-12
MITIGATE COVID-19: A clinical trial of icosapent ethyl(VASCEPA) in patients with established atherosclerotic cardiovascular disease who are at elevated risk of experiencing moderate to severe COVID-19 Atherosclerosis, Cardiovascular disease, Coronavirus disease 19 infection icosapent ethyl alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Amarin Corp plc, Kaiser Permanente MITIGATE COVID-19 Phase Not Applicable Status not specified 0 1500 Dr. Alan S. Go, Dr. Andrew P. Ambrosy, 2020-08-11
Tenecteplase in Patients With COVID-19 Coronavirus disease 19 infection, Respiratory failure heparin plus tenecteplase Tissue plasminogen activator stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Mount Sinai Medical Center Genentech Inc US 2020-08-31 2021-04-30 GCO 20-1764, NCT04505592 Phase 2 Clinical Not yet recruiting 1 8 Months 60 Denise Balili, MS, Hooman Poor, MD, J Mocco, MD, Lisa Genadry, Sukaina Davdani 2020-08-12
A Randomized, Controlled, Multicenter, Parallel-Group Phase II Study to Evaluate the Efficacy and Safety of Intramuscular Injections of PLX-PAD for the Treatment of severe COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome PLX stem cell therapy, Pluristem/Cha Bio & Diostech alone IL-6 receptor agonist Pluristem Therapeutics Inc Germany Phase 2 Clinical Not yet recruiting 1 40 2020-08-13
A trial to evaluate Organicell Flow in patients with COVID-19 admitted to the ICU Coronavirus disease 19 infection Organicell Flow alone Organicell Regenerative Medicine US Phase Not Applicable Status not specified 1 1 2020-08-11
A trial to evaluate Organicell Flow in patient with COVID-19 related respiratory impairment and acute kidney injury Coronavirus disease 19 infection, Renal injury, Respiratory disease Organicell Flow alone Organicell Regenerative Medicine Georgia Phase Not Applicable Status not specified 1 1 2020-08-11
SISCOVID: Follow-up of Respiratory Sequelae of Hospitalized Patients With COVID-19 Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Groupe Hospitalier de la Region de Mulhouse et Sud Alsace France 2020-06-10 2021-06-30 GHR 1052, IDRCB 2020-A01089-30, NCT04505631, SISCOVID Phase Not Applicable Recruiting 14 12 Months 100 Acya Bizieux, MD, Amélie Leurs, MD, Cécile Carvallo, MD, Cécilia Nocent-Ejnaini, MD, Didier Debieuvre, MD, François Goupil, MD, George-Daniel Calcaianu, MD, Hugues Morel, MD, Jean-Philippe Oster, MD, Johanna Claustre, MD, Laurent Portel, MD, Marie Diesel, Marie-Germaine Legrand, MD, Nadine Paillot, MD, Stéphane Hominal, MD, Stéphanie Romanet, MD 2020-08-12
A trial to evaluate Organicell Flow in patients with mild to moderate respiratory distress due to COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome Organicell Flow alone Organicell Regenerative Medicine US Phase Not Applicable Status not specified 1 1 2020-08-24
A phase I/IIa clinical study to assess UMSC-01 for the treatment of patients with COVID-19 infection Coronavirus disease 19 infection UMSC-01 alone Ever Supreme Bio Technology Co Ltd US ES-CMSC01-C1101 Phase 1/Phase 2 Clinical Not yet recruiting 1 2020-08-11
A clinical trial of JAN-101 for the potential treatment of vascular complications in COVID-19 patients Coronavirus disease 19 infection, Vascular disease JAN-101 alone Cato Holding Ltd, JanOne Inc US Phase Not Applicable Planned 1 Dr. Amol Soin 2020-08-11
CorKid: CorKid (COVID19/ SARS-CoV-2 seroconversion in kids) Coronavirus disease 19 infection Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Universitätskinderklinik im St.-Josef Hospital Klinikum der Ruhr-Universität-Bochum German Federal Ministry of Education and Research, Ruhr Universitat Bochum Germany 2020-06-08 20-6927, CorKid, DRKS00022434 Phase Not Applicable Recruiting 3 3000 Corkid Studienteam, Thomas Lücke 2020-08-26
Role of Famotidine in the Symptomatic Improvement of COVID-19 Patients Coronavirus disease 19 infection famotidine (Famotac) alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chattogram General Hospital The First Affiliated Hospital of Xi'an Jiaotong University Bangladesh 2020-08-01 2020-10-30 10000753/980, NCT04504240 Phase 3 Clinical Recruiting 2 2 Months 200 Abu Taiub Mohammed Mohiuddin Chowdhury, Abu Taiub Mohammed Mohiuddin Chowdhury, MBBS, MD, Aktar Kamal, MD, PhD, H.M. Hamidullah Mehedi, MBBS, FCPS, H.M.Hamidullah Mehedi, H.M.Hamidullah Mehedi, MMBS, FCPS 2020-08-13
Patients' Experiences in a Medicalized Hotel for COVID-19 Acute Care Support Coronavirus disease 19 infection Hospital Clinic of Barcelona Spain 2020-05-15 2020-06-06 MEDICALITZED HOTEL COVID-19, NCT04503434 Phase Not Applicable Completed 1 517 Carme Hernandez, PhD 2020-08-12
DenutCOVID: Nutritional Assessment of Hospitalized Patients With COVID-19 Coronavirus disease 19 infection, Nutritional disorder nutrition testing alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Lille Catholic University France 2020-05-25 2021-06-30 DenutCOVID, NCT04503525, RC-P00100 Phase Not Applicable Recruiting 1 13 Months 50 Amel Boulafa, Master, Amelie LANSIAUX, MD, PhD, Arnaud CORTET, PhD, Arnaud Cortet, MD 2020-08-12
A clinical study to assess the safety and efficacy of ANA-001 (niclosamide capsules) as well as its ability to show a clinical improvement in hospitalized patients with COVID-19 Coronavirus disease 19 infection repurposed niclosamide (oral/capsule, COVID-19), ANA Therapeutics alone ANA Therapeutics US Phase Not Applicable Not yet recruiting 2 400 2020-08-14
An observational study on the optimization of hydroxychloroquine dosing for the treatment of patients with COVID-19 Coronavirus disease 19 infection hydroxychloroquine alone, azithromycin plus hydroxychloroquine University of California San Francisco Phase Not Applicable Status not specified 0 116 2020-08-12
Ultrafast Screening of novel coronavirus pneumonia (COVID-19) by Machine Learning Analysis of Exhaled NO Coronavirus disease 19 infection, Viral pneumonia preliminary screening( Machine Learning Analysis of Exhaled NO ) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Liyuan Hospital Shandong University China 2020-03-01 2021-06-30 ChiCTR2000035342 Phase 0 Clinical Recruiting 2 16 Months Jing Ma, Wei-Qiao Deng 2020-08-11
Covid-19 Messaging to Underserved Communities - Second Experiment Coronavirus disease 19 infection AMA Acknowledgement Drug Pricing alone, Acknowledgement Racial Injustice AMA alone, Acknowledgement alone, Informational Videos alone, No Racial Inequality Highlighting alone, Racial Inequality Highlighted alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), African Ancestry National Bureau of Economic Research Inc Harvard University, Massachusetts General Hospital, Stanford University, Yale University US 2020-08-31 2021-09-30 2029880, NCT04502056 Phase Not Applicable Not yet recruiting 1 13 Months 20000 Esther Duflo 2020-08-13
Parent Telehealth Intervention for Children With Autism Autism, Coronavirus disease 19 infection Responsive training alone, Video feedback alone Healthy volunteers accepted, Infants (6-23 months), Preschool Children (2-5 yrs) Northwestern University US 2020-03-06 2021-07-31 NCT04501588, STU00201708 Phase 2 Clinical Recruiting 1 16 Months 40 Laura Sudec, MSW, Megan Y Roberts, PhD 2020-08-13
Western Kenya Integrated COVID-19 Response Coronavirus disease 19 infection Training clinicians in basic critical care alone, Training of youth, community health assistants and community health workers. alone, management of severe COVID-19 cases alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) SURGICAL SYSTEMS RESEARCH GROUP Tropical Institute of Community Health and Development (TICH), Wellcome Trust Kenya 2020-05-18 2020-08-19 001, NCT04501458 Phase Not Applicable Recruiting 1 3 Months 200000 Neema Kaseje, MD 2020-08-12
Psychological Symptoms and Families of COVID-19 Patients Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder, Psychiatric disorder Post-ICU discharge survey and Interview alone, Written Summary of Rounds alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rush University Medical Center US 2020-08-20 2021-09-15 20071101, NCT04501445 Phase Not Applicable Not yet recruiting 1 12 Months 100 Jared A Greenberg 2020-08-12
COVID-19 Project ECHO in Nursing Homes Coronavirus disease 19 infection Project ECHO alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Milton S. Hershey Medical Center US 2020-08-31 2022-07-31 NCT04499391, PCORI NURSING HOMES Phase Not Applicable Not yet recruiting 1 23 Months 100 Erica Francis, Jennifer Kraschnewski 2020-08-14
BONSAI: Burnout and Distress prevention With cannabidiol in Front-line Health Care workers dealing with COVID-19 Acute stress disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder cannabidiol alone, fitness video watching alone, supporting motivational video watching alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) University of Sao Paulo Brazil 2020-06-16 2020-09-30 30504620.4.0000.5440, BONSAI, BONSAI Study, NCT04504877 Phase 2/Phase 3 Clinical Recruiting 1 3 Months 102 Jose A. Crippa, MD, PhD, Jose Alexandre de Souza Crippa, Julia C Pacheco, MsC, Julia C. Pacheco, MsC 2020-08-12
CovAb: COVID-19 Seroprevalence Study in ITM Staff Coronavirus disease 19 infection Anti-SARS-CoV-2 ELISA (EUROIMMUN) alone, WANTAI SARS-CoV-2 Ab ELISA (WANTAI SARS-CoV-2 Diagnostics) alone Institute of Tropical Medicine, Belgium Belgium 2020-08-01 2020-09-30 CovAb, NCT04503447, SARSCOV2SEROPREVALENCEITMSTAFF Phase Not Applicable Recruiting 1 2 Months 430 Bart Karl Jacobs, Lut Lynen, Marie Laga, Marjan Van Esbroeck, Marjan Van Esbroeck, MD, Nikki Foqué, Sarah Gils 2020-08-12
A pahse Ib/IIa clinical trail of Amilo-5MER for study of biomarkers (SAA in serum) for IBD and for the treatment of COVID-19 Coronavirus disease 19 infection, Inflammatory bowel disease Amilo-5MER alone Apolipoprotein B modulator, IL-6 receptor antagonist, Serum amyloid A protein modulator, Transthyretin modulator Galmed Pharmaceuticals Ltd Hebrew University of Jerusalem 2021-12-31 Phase 1/Phase 2 Clinical Planned 0 2020-08-17
The first human study of Amilo-5MER for the reduction of IL-6 secretion Coronavirus disease 19 infection, Respiratory distress syndrome Amilo-5MER alone Apolipoprotein B modulator, IL-6 receptor antagonist, Serum amyloid A protein modulator, Transthyretin modulator Galmed Pharmaceuticals Ltd Hebrew University of Jerusalem, Yissum Research Development Co UK 2020-12-31 Phase 1 Clinical Planned 1 2020-08-17
INSPIRE: A randomized, placebo-controlled, double-blind, multicenter, phase II clinical trial to assess safety and efficacy of CAP-1002 in patients with severe or critical COVID-19 infection Coronavirus disease 19 infection CAP-1002 alone Capricor Therapeutics Inc US 2020-09-30 INSPIRE Phase 2 Clinical Not yet recruiting 1 60 2020-08-27
300BCG: A study to evaluate BCG vaccine in a group of healthy subjects Coronavirus disease 19 infection BCG vaccine alone Healthy volunteers accepted Radboud University Netherlands 300BCG Phase Not Applicable Status not specified 1 2020-08-11
A Trial to Evaluate Safety and Efficacy of Rivaroxaban (COVID-19) Coronavirus disease 19 infection rivaroxaban alone Factor Xa antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bill & Melinda Gates Medical Research Institute 2020-08-31 2020-12-31 GATES MRI - COD-01-T01-01, NCT04504032 Phase 2b Clinical Not yet recruiting 0 4 Months 600 Gates MRI, GatesMRI 2020-08-24
VisVasc COVID-19: Visualizing blood vessel disease in the eye in COVID-19 Coronavirus disease 19 infection, Retinopathy, Vascular disease fundal photography alone, optical coherence tomography alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) North Bristol NHS Trust Southmead Hospital, Wellcome Trust UK 2020-08-06 2021-08-05 IRAS 286315, ISRCTN59449699, VisVasc COVID-19 Phase Not Applicable Not yet recruiting 2 12 Months 30 Dr Rice 2020-08-14
CANCOVID-19: Add on to Azythromycine, Phytomedicine and/or Antimalarial Drug Versus Hydroxychloroquine in Uncomplicated COVID-19 Patients Coronavirus disease 19 infection Variable regimens including Cospherunate (artesunate + amodiaquine) , azithromycin , phytomedicine tablet (Asen) Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institute for Research and Development of Medicinal and Food Plants of Guinea Guinea 2020-06-01 2020-09-30 CANCOVID-19, NCT04502342, RDIMFPG Phase 2 Clinical Recruiting 1 4 Months 30 Mamadou A Baldé 2020-08-10
BCG vaccine use to prevent COVID-19 in health care workers Coronavirus disease 19 infection BCG vaccine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Universidade Do Estado Do Rio De Janeiro, Universidade Federal do Rio de Janeiro Brazil 2020-07-15 RBR-5ysj54, U1111-1253-9610 Phase 2/Phase 3 Clinical Not yet recruiting 1 1000 Fernanda Carvalho de Queiroz Mello 2020-08-18
A large-scale trial to evaluate Gam-COVID-Vac for the prevention of Covid-19 Coronavirus disease 19 infection Sputnik V alone COVID19 Spike glycoprotein modulator Gamalei Institute of Epidemiology and Microbiology Phase 3 Clinical Planned 0 2020-08-13
Pred-MAKER: Prediction of Major Adverse Kidney Events and Recovery Coronavirus disease 19 infection, Renal disease KidneyIntelX alone Mount Sinai School of Medicine, Renalytix AI plc US Pred-MAKER Phase Not Applicable Status not specified 1 Dr. Steven Coca 2020-08-10
MASKeD-COVID: Multicenter Assessment of Survivors for Kidney Disease After COVID-19 Coronavirus disease 19 infection, Renal disease, Renal failure KidneyIntelX alone Mount Sinai School of Medicine, Renalytix AI plc US 2020-08-03 MASKeD-COVID Phase Not Applicable Recruiting 2 4000 F. Perry Wilson, Matthias Kretzler 2020-08-10
PERSONAL-COVIDBP: Personalised Electronic Record Supported OptimisatioN when ALone for Patients with Hypertension- Pilot Study for Remote Medical Management of Hypertension During the COVID-19 Pandemic Coronavirus disease 19 infection, Hypertension amlodipine alone Calcium channel inhibitor L-type Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Queen Mary University of London Technology Strategy Board UK 2020-07-17 2020-002494-10, PERSONAL-COVIDBP Phase 4 Clinical Recruiting 1 1000 Dr David Collier 2020-08-10
CLiCK Study: A study to look at the safety and success of using Clazakizumab in patients who have kidney disease and COVID-19 Coronavirus disease 19 infection clazakizumab alone IL-6 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Imperial College London Vitaeris Inc UK 2020-07-24 2020-002476-13, 20HH5958, CLiCK Study Phase 2 Clinical Recruiting 1 20 2020-08-23
Effects of Tocilizumab and its combination with Vitamin D to treat the increased defensive response in COVID-19 Coronavirus disease 19 infection tocilizumab (intravenous), Roche/Chugai alone IL-6 receptor antagonist, IL-6 receptor modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Universitario de Móstoles Servicio Regional De Salud De La Consejeria De Salud De La Comunidad De Madrid Spain 2020-06-10 2020-001903-17, HMos-012020 Phase 3 Clinical Recruiting 1 120 MEDICAL DIRECTOR 2020-08-24
An initial study to evaluate the accuracy of NeuCovix for the detection of neutralizing antibodies in patients with COVID-19 infection Coronavirus disease 19 infection NeuCovix alone Axim Biotechnologies Inc Phase Not Applicable Status not specified 0 2020-08-10
Efficacy and safety of Montelukast as add on treatment to the novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection montelukast sodium alone Leukotriene D4 antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Porto Portugal 2020-07-06 2020-001747-21, ISPUP2020CT1 Phase 4 Clinical Recruiting 1 160 Clinical trials information 2020-08-10
ARCADIA: AZD-1656 in Diabetic Patients Hospitalised With Suspected or Confirmed COVID-19 Coronavirus disease 19 infection, Insulin dependent diabetes, Non-insulin dependent diabetes AZD-1656 alone Glucokinase stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) St George Street Capital UK 2020-08-31 2020-12-31 2020-002211-21, ARCADIA, NCT04516759, SGS.1656.201 Phase 2 Clinical Not yet recruiting 1 4 Months 150 Kieran McCafferty, MD, Mike Johnson 2020-08-20
SPESELPIS: A Trial of NT-I7 in COVID-19 Coronavirus disease 19 infection efineptakin alfa alone, standard of care alone IL-7 receptor agonist, Interleukin-7 ligand Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) National Institute of Allergy and Infectious Diseases, National Institutes of Health, NeoImmuneTech Inc, University of Nebraska Medical Center National Institute of Allergy and Infectious Diseases US 2020-08-31 2021-12-31 NCT04501796, NIT-116 (SPESELPIS), SPESELPIS, SPESELPIS Phase 1 Clinical Recruiting 2 16 Months 30 Amy Haberman, Andre Kalil, M.D., M.P.H, Anela Kellogg, Megan Anderson, NgocDiep 2020-08-17
TICO/ACTIV-3: Therapeutics for Inpatients With COVID-19 Coronavirus disease 19 infection LY-CoV555 plus remdesivir COVID19 Spike glycoprotein modulator, COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Allergy and Infectious Diseases, National Institutes of Health AIDS Clinical Trials Group, Cardiothoracic Surgical Trials Network, Copenhagen University, International Network for Strategic Initiatives in Global HIV Trials (INSIGHT), Medical Research Council, National Centre in HIV Epidemiology and Clinical Research, National Heart Lung and Blood Institute, Prevention and Early Treatment of Acute Lung Injury (PETAL), US Department of Veterans Affairs, Washington D.C. Veterans Affairs Medical Center US 2020-08-04 2021-07-31 014 / ACTIV-3, NCT04501978, TICO/ACTIV-3 Phase 3 Clinical Recruiting 8 11 Months 10000 Alan Moskowitz, M.D, Annetine Gelijns, Ph.D, Do not include personal information in email, Do not included personal information in email, Jens Lundgren, M.D, Prof. James Neaton, Rachel Ramoni, D.M.D, Sc.D, Taylor Thompson, M.D 2020-08-22
Effectiveness of gargle and nasal spray with Hydrogen Peroxide as an auxiliary treatment for corona virus Coronavirus disease 19 infection Hydrogen Peroxide alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidado de Passo Fundo Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Brazil 2020-06-26 2020-08-30 31752720.1.0000.5342, 4.071.153, RBR-6sx3sz, U1111-1254-2210 Phase 1/Phase 2 Clinical Recruiting 1 2 Months 240 Henrique Cesca, Marielle Bazzo Di Domênico, Pedro Henrique Corazza 2020-08-17
Behavior During and After COVID-19-crisis Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Bern University of Applied Sciences Switzerland 2020-04-01 2022-12-31 BFH CORONA, NCT04502108 Phase Not Applicable Recruiting 2 33 Months 1000 Heiner Baur, Ph.D, Slavko Rogan, Slavko Rogan, Ph.D 2020-08-11
Study to Evaluate the Efficacy and Safety of Remdesivir (GS-5734) Treatment of Coronavirus Disease 2019 (COVID-19) in an Outpatient Setting Coronavirus disease 19 infection remdesivir alone COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gilead Sciences Inc 2020-09-30 2021-01-31 2020-003510-12, GS-US-540-9012, NCT04501952 Phase 3 Clinical Not yet recruiting 0 4 Months 1230 Gilead Clinical Study Information Center, Gilead Study Director 2020-08-13
PHYTCOVID-19: Phytomedicines Versus Hydroxychloroquine as an Add on Therapy to Azythromycin in Asymptomatic COVID-19 Patients Coronavirus disease 19 infection azithromycin alone, plant species powder alone, Variable regimens including Quinquina-Stevia , azithromycin , hydroxychloroquine Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institute for Research and Development of Medicinal and Food Plants of Guinea Guinea 2020-06-01 2020-09-30 IRDPMAG, NCT04501965, PHYTCOVID-19 Phase 2 Clinical Recruiting 1 4 Months 231 Mamadou A Baldé, Mohamed Cissé, Saliou Sow 2020-08-14
Short-term Impact of COVID-19 Lockdown on Metabolic Control of Type 2 Diabetes Coronavirus disease 19 infection, Non-insulin dependent diabetes antidiabetic treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Pisa Italy 2020-03-11 2020-06-30 AS0007, NCT04501991 Phase Not Applicable Completed 1 3 Months 114 Anna Solini, MD, PhD 2020-08-11
Effect of finasteride on COVID-19 treatment Coronavirus disease 19 infection, Viral pneumonia Variable regimens including ceftriaxone , finasteride , hydroxychloroquine 5-Alpha-reductase inhibitor Male, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Qazvin University Of Medical Sciences Iran 2020-03-20 IR.QUMS.REC.1399.016, IRCT20200505047318N1 Phase 3 Clinical No longer recruiting 2 80 Abbas Allamy, Dr.Abbas Allami, Dr.Abbas Allamy 2020-08-10
Impact of Spectacles on Compliance to Mask-wearing Directives Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Of Thrace Greece 2020-06-25 2020-08-14 ES8/TH5/25-06-2020, NCT04501172 Phase Not Applicable No longer recruiting 1 1 Month 1214 Labiris Georgios, MD, PhD 2020-08-12
Prospective Study initiated by University Hospital Rostock concerning COVID-19 in mothers, nursery and school teachers of children in Rostock Coronavirus disease 19 infection biological sampling alone, polymerase chain reaction alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Universitätsmedizin Rostock Deutsche Forschungsgemeinschaft (DFG), German Federal Ministry of Education and Research Germany 2020-08-10 A 2020-0090, DRKS00022504 Phase Not Applicable Recruiting 1 600 Emil C. Reisinger, Hilte Geerdes-Fenge 2020-08-26
Evaluating the effect of Ivermectin on COVID-19 patients Coronavirus disease 19 infection ivermectin alone Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ahvaz University of Medical Sciences Iran 2020-07-30 IR.AJUMS.REC.1399.322, IRCT20200404046937N4 Phase 2 Clinical Recruiting 2 60 Mehran Varnaseri, Mehran Varnasseri, Mohammad Badavi 2020-08-10
A clinical study to evaluate the effect of BioTech Life Sciences proprietary formulas on long-term patient symptoms related to COVID-19 Post-Viral Fatigue (long-haulers) and chronic fatigue syndrome Chronic fatigue syndrome, Coronavirus disease 19 infection proprietary formulas, BioTech Life Sciences alone BioTech Life Sciences Phase Not Applicable Recruiting 0 2020-08-07
A phase II clinical trial of VBI-2900 for the potential treatment of SARS-CoV-2 infection Coronavirus disease 19 infection VBI-2901 alone VBI Vaccines Inc 2020-12-31 Phase 2 Clinical Planned 0 2020-08-07
Efficacy of Vitamin D Treatment in Pediatric Patients Hospitalized by COVID-19 Coronavirus disease 19 infection, Respiratory disease cholecalciferol alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) Coordinacion de Investigacion en Salud Hospital General de Mexico, Hospital Infantil de Mexico Federico Gomez Mexico 2020-07-15 2021-04-30 NCT04502667, R-2020-3603-020 Phase 3 Clinical Recruiting 1 9 Months 40 Carla Castuera Martinez, Carmen Espinosa-Sotelo, MD, Guadalupe Miranda-Novales, PhD, JESSIE ZURITA-CRUZ, JESSIE ZURITA-CRUZ, PhD, Jessie N ZURITA-Cruz, Jessie ZURITA-CRUZ, Mardia Lopez-Alarcon, PhD, Miguel Angel Villasis-Keever, Miguel Villasis-Keever, PhD 2020-08-10
Fiberoptic Bronchoscopy and Bronchoalveolar Lavage in Critically Ill Ventilated Patients Coronavirus disease 19 infection, Respiratory disease PulmoVista 500 (Draeger) alone, bronchoalveolar lavage analysis alone, electrical impedance tomography alone, fiberoptic bronchoscopy alone, multiple arterial blood gas test alone, realtime thoracic impedance analysis alone, sodium chloride alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Erasme Hospital Belgium 2020-08-06 2020-09-30 NCT04502368, P2020/375, SRB2020-289 Phase Not Applicable Recruiting 3 1 Month 15 Francesco Ricottilli,, Francesco Ricottilli, MD, Leda Nobile, MD 2020-08-11
ACTIV-2: A Phase II clinical trial to evaluate the safety and efficacy of LY-CoV555 for COVID-19 Coronavirus disease 19 infection LY-CoV555 alone COVID19 Spike glycoprotein modulator National Institute of Allergy and Infectious Diseases, National Institutes of Health US ACTIV-2 Phase 2 Clinical Recruiting 1 Davey Smith, David Wohl, Kara W. Chew 2020-08-11
One-year Cardiac Follow-up of Patients With COVID-19 Pneumonia Cardiovascular disease, Coronavirus disease 19 infection, Viral pneumonia clinical test alone, instrumental test alone, laboratory diagnostics tests alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Federal Noe G Bjudzhetnoe Uchrezhdenie Nii Onkologii Sib Otdel Rossijskoj Akademii Med Nauk Fgbu Nii Russian Federation 2020-07-19 2021-12-31 NCT04501822, TCRC-COVID Phase Not Applicable Recruiting 1 17 Months 380 Elena Yaroslavskaya, PhD, Ivan Bessonov, PhD 2020-08-10
Inova-CCP: Open-label Treatment of Severe Coronavirus Disease 2019 (COVID-19) With Convalescent Plasma Coronavirus disease 19 infection COVID-19 convalescent plasma (CCP) transfusion alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Inova Health Care Services US 2020-06-06 2021-12-31 INOVA COVID-19 CCP, Inova-CCP, NCT04502472 Phase 2/Phase 3 Clinical Recruiting 1 18 Months 200 Anne Brown, M.D., Anne W Brown, MD, Edwinia Battle, BSN, Merte Lemma-Woldehanna, BS, Merte Lemme-Woldehanna, BS 2020-08-10
Opaganib-RHB: Treatment of COVID-19 With Opaganib in Patients With Pneumonia Requiring Oxygen Coronavirus disease 19 infection, Viral pneumonia opaganib alone Dihydroceramide delta 4 desaturase inhibitor, Sphingosine kinase 2 inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) RedHill Biopharma Ltd Israel 2020-08-31 2021-06-30 ABC-112, NCT04502069, Opaganib-RHB Phase 1/Phase 2 Clinical Terminated 1 10 Months Mark L Levitt, MD 2020-08-27
A clinical trial of cannabinoid Sol-gel for the treatment of covid-19 Coronavirus disease 19 infection cannabinoid Sol-gel alone PreveCeutical Medical Inc, Veristat, Inc. Phase Not Applicable Planned 0 2020-08-07
Exhaled Breath Particles as a Clinical Indicator for Lung Injury and Acute Respiratory Distress Syndrome (ARDS) Acute lung injury, Coronavirus disease 19 infection, Lung infection, Respiratory distress syndrome exhaled breath particles PCR test alone, real time particle flow rate prediction test alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Skåne University Hospital Sweden 2020-05-01 2024-05-01 NCT04503057, PEX ARDS Phase Not Applicable Recruiting 1 48 Months 300 Leif Pierre, PhD, Sandra Lindstedt Ingemansson, MD, PhD 2020-08-10
CODIS: Cardiac Rehabilitation and Ongoing Physical Activity During COVID-19 Cardiovascular disease, Coronavirus disease 19 infection cycle ergometry test alone, semi-structured qualitative interview alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ludwig Boltzmann Institute for Digital Health and Prevention Paracelsus Medical University Austria 2020-07-14 2020-12-31 23_CODIS, CODIS, NCT04501432 Phase Not Applicable Recruiting 1 5 Months 40 Josef Niebauer, Prof.Dr.Dr., Mahdi Sareban, Dr. Dr. med., Mahdi Sareban, Dr.Dr.med., Stefan T Kulnik, PhD MRes 2020-08-23
Studying the progression and the consequences of the new Coronavirus in Brazil Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundacao Oswaldo Cruz (Fiocruz) Conselho Nacional de Desenvolvimento Cientifico e Tecnologico - CNPq Brazil 2020-08-03 32874720.8.1001.5262, 4.148.652, RBR-8hmb2r, U1111-1255-9610 Phase Not Applicable Not yet recruiting 1 1200 André Siqueira, Giselle Duarte, José Moreira 2020-08-26
Intravenous Immunoglobulin (IVIG, Bioven) Efficacy Assess for COVID-19/SARS-CoV-2 Severe Pneumonia Complex Treatment Coronavirus disease 19 infection, Lung inflammation, Respiratory distress syndrome, Respiratory failure, Respiratory tract infection, Viral pneumonia Bioven alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) BIOPHARMA PLASMA LLC Ukraine 2020-05-07 2020-09-30 2020-BV-BP, NCT04500067 Phase 3 Clinical Recruiting 8 4 Months 76 Anatolii M Deyneka, MD, Andrii R Rybakov, MD, Igor P Bernik, MD, Iryna V Kobylyan, MD, Kateryna Yu Romanchuk, MD, Khrystyna V Lewandowska, MD, Larisa V Moroz, MD, Lilia Ya Romaniv, MD, Liliya B Kurilyak, MD, Ludmila K Boshkova, MD, Maryana V Gurkivska, MD, Mikhail G Kuzyuk, MD, Natalia B Zhevoronko, MD, Nataliya O Ivanchenko, MD, Oksana I Paraschuk, MD, Oksana M Mazur, MD, Oksana Ya Kadubets', MD, Oleg K Yakovenko, MD, Olena Ya Kobrynska, MD, Olga V Pronina, MD, Pavlo A Gashchishin, MD, Roman M Fishchuk, MD, Ruslan V Mazur, MD, Sergii L Zanozdra, MD, Sergii O Solyarik, MD, Svitlana Y Lavryukova, MD, Taisiya V Vzhetson, MD, Tamila I Aleksanyan, MD, Vasyil S Kopcha, MD, Prof., Viktor P Tokarev, MD, Vitalii A Lukiyanchuk, MD, Yaroslav G Zhebelenko, Ph.D., MD 2020-08-19
A clinical trial of Interleukin-6 inhibitorsfor the effective treatment of Coronavirus disease 19 infection Coronavirus disease 19 infection sarilumab plus tocilizumab (intravenous), Roche/Chugai IL-6 receptor antagonist, IL-6 receptor modulator Boston Medical Center Corp, ROCHE/CHUGAI Pharma AG US Phase Not Applicable Status not specified 1 255 2020-08-14