Last updated: Sep 01, 2020 - 02:00 BST
| Respiratory Syncytial Virus Infection May be More Dangerous in Neonate |
Coronavirus disease 19 infection, Respiratory syncytial virus infection |
Bio-Speedy qPCR detection kit alone, Bosphore Respiratory Pathogens Panel Kit V4 alone, biological sampling alone |
|
Newborn Infants (up to 5 months) |
Dr. Behcet Uz Children's Hospital |
|
Turkey |
2020-03-01 |
2020-08-31 |
2020/522, NCT04531735 |
Phase Not Applicable |
No longer recruiting |
0 |
6 Months |
28 |
Senem Alkan Özdemir |
2020-08-31 |
| Camostat and Artemisia Annua Versus Placebo in COVID-19 Outpatients |
Coronavirus disease 19 infection, Viral pneumonia |
Artemisia annua alone, camostat mesylate alone |
Serine protease inhibitor, Transmembrane serine protease 2 inhibitor, Trypsin inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Instituto Nacional de Ciencias Medicas y Nutricion |
Hospital General Dr. Manuel Gea González, Hospital General de Mexico, Instituto Nacional de Cardiologia Ignacio Chavez |
Mexico |
2020-08-31 |
2021-02-28 |
3421, NCT04530617 |
Phase 2 Clinical |
Not yet recruiting |
0 |
6 Months |
360 |
David Kershenobich Stalnikowitz, MD, Jose G Gotes Palazuelos, MD |
2020-08-31 |
| Immune Cell Subgroups in Covid 19 Patients |
Coronavirus disease 19 infection, Lymphocytopenia, Respiratory failure |
Flow cytometric analysis alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Istanbul Training and Research Hospital |
|
Turkey |
2020-08-15 |
2020-09-15 |
COVID CELL, NCT04531319 |
Phase Not Applicable |
Recruiting |
0 |
1 Month |
60 |
Tahir Talat Yurttas, MD, Ufuk Oguz Idiz, Assoc. Prof |
2020-08-31 |
| Timing of Corticosteroids in COVID-19 |
Coronavirus disease 19 infection |
dexamethasone alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
ClinAmygate |
|
Egypt |
2020-08-26 |
2020-11-01 |
NCT04530409, PR0012 |
Phase 4 Clinical |
Not yet recruiting |
0 |
2 Months |
450 |
Emad Roushdy, Dr |
2020-08-31 |
| Efficacy and Safety of Recovered Covid-19 Plasma Transfusion to Covid-19 Severly Ill Patients |
Coronavirus disease 19 infection |
recovered Covid-19 patient plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
South Valley University |
|
Egypt |
2020-05-29 |
2020-09-01 |
NCT04530370, OSSAMAHAMDYRESEARCHER7 |
Phase 0 Clinical |
Recruiting |
0 |
3 Months |
30 |
Gad S Gad, MD, Gad s Gad, MD, Ossama Hamdy Salman, ossama h salman, MD,PhD |
2020-08-31 |
| Outpatient Use of Ivermectin in COVID-19 |
Coronavirus disease 19 infection |
ivermectin alone |
Chloride channel modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Temple University |
|
US |
2020-10-01 |
2021-12-31 |
1285242, NCT04530474 |
Phase 3 Clinical |
Not yet recruiting |
0 |
15 Months |
200 |
Derek Isenberg, MD, Nina Gentile, MD |
2020-08-31 |
| Back to School COVID-19 Simulation Study |
Coronavirus disease 19 infection |
Face mask alone |
|
Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Hospital for Sick Children |
|
Canada |
2020-08-10 |
2020-12-31 |
1000071861, NCT04531254 |
Phase Not Applicable |
No longer recruiting |
1 |
4 Months |
240 |
Michelle Science |
2020-08-31 |
| EPICOVID-PAHANG: Epidemiological study of COVID-19 in Pahang |
Coronavirus disease 19 infection |
|
|
|
|
|
Malaysia |
2020-08-28 |
2020-12-31 |
56085, EPICOVID-PAHANG, NMRR-20-1825-56085 |
Phase Not Applicable |
Status not specified |
1 |
4 Months |
|
Dr Che Asiah binti Taib, Dr muhammad 'adil bin zainal abidin |
2020-08-31 |
| Drug utilization for Covid-19 |
Coronavirus disease 19 infection |
|
|
|
International Islamic University Malaysia |
|
Malaysia |
2020-10-01 |
2021-09-30 |
56013, NMRR-20-1823-56013 |
Phase Not Applicable |
Status not specified |
1 |
12 Months |
|
Assoc Prof Dr Che Suraya Haji Mohd Zin |
2020-08-31 |
| RESIST: Clinical Trial of Efficacy, Safety, and Immunogenicity of Gam-COVID-Vac Vaccine Against COVID-19 |
Coronavirus disease 19 infection |
Sputnik V alone |
COVID19 Spike glycoprotein modulator |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Health Ministry of the Russian Federation Collaborator |
Crocus Medical B.V |
Russian Federation |
2020-08-31 |
2021-05-01 |
04-GAM-COVID-VAC-2020, NCT04530396, RESIST |
Phase 3 Clinical |
Not yet recruiting |
0 |
8 Months |
40000 |
Elena Nurmukhametova, MD, PhD, Elena Smolyarchuk, MD, PhD, Inna Dolzhikova, PhD, Irina Gagarina, MD, Irina Shestakova, MD, Karin Mirzoev, MD, Marina Rusanova, MD, Semyon Maksimov, MD, Tatiana Shimonova, MD |
2020-08-31 |
| Glycemic Control Among Children and Adolescents With Type 1 Diabetes During COVID-19 Pandemic in Egypt |
Coronavirus disease 19 infection, Insulin dependent diabetes |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Ain Shams University |
|
Egypt |
2020-07-07 |
2020-08-31 |
FMASU P66/2020, NCT04531111 |
Phase Not Applicable |
Recruiting |
0 |
1 Month |
150 |
Khadiga Eltonbary, Yasmine Ehenawyl, Yasmine Elhenawy |
2020-08-31 |
| COVID-19 Saliva Test Research Study |
Coronavirus disease 19 infection |
Chronomics test alone, nasopharyngeal tests alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Chronomics Ltd |
|
UK |
2020-06-29 |
2020-09-29 |
283560, NCT04531501 |
Phase Not Applicable |
Recruiting |
2 |
3 Months |
400 |
Hannah Howlett, Janet Forkes, Sana Wahid |
2020-08-31 |
| SAINT-PERU: Randomized, phase IIa clinical trial to compare the efficacy of ivermectin versus placebo to obtain negative PCR results in patients with early phase COVID-19 |
Coronavirus disease 19 infection |
ivermectin alone |
Chloride channel modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universidad Peruana Cayetano Heredia |
|
Peru |
2020-09-07 |
|
PER-034-20, SAINT-PERU |
Phase 2a Clinical |
Not yet recruiting |
1 |
|
68 |
Carlos Chaccour Díaz, César Cárcamo Cavagnaro, César Ugarte Gil, German Javier Malaga Rodrìguez, Germán Málaga Rodríguez, Hansel Kevin Mundaca Hurtado, PATRICIA JANNET GARCÍA FUNEGRA, Patricia Hilda León Paredes, Patricia Jannet García Funegra |
2020-08-31 |
| AUNA 20-01: Phase II study of efficacy and safety of plasma from convalescent patients with COVID-19 in patients with moderate disease |
Coronavirus disease 19 infection |
convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
|
|
Peru |
2020-07-06 |
|
AUNA 20-01, PER-031-20 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
50 |
Alejandro DALY TURCKE, Alfredo Eric Goytendia Cortez, Antonio Alfredo Carrasco Yalan, INA NOELIA PÉREZ HUAYNALAYA, Ina Noelia Pérez Huaynalaya, Joseph Arturo Pinto Oblitas, Maria Consuelo Requena Medina, Victor Romario Pizarro Herrera |
2020-08-31 |
| A global, randomised, placebo-controlled Phase II trial of LYT-100 for the treatement of serious respiratory complications linked to inflammation and fibrosis that persist following the resolution of SARS-CoV-2 (COVID-19) infection |
Coronavirus disease 19 infection, Fibrosis, Respiratory disease, Respiratory tract inflammation |
deupirfenidone alone |
PDGF receptor antagonist, TGF beta receptor antagonist, p38 MAP kinase inhibitor |
|
PureTech Health Plc |
|
|
2020-09-30 |
|
|
Phase 2 Clinical |
Planned |
0 |
|
|
|
2020-08-31 |
| Randomized, Blind, Placebo-controlled, I/II Phase QazCovid-in COVID-19 |
Coronavirus disease 19 infection |
QazCovid-in COVID-19 inactivated vaccine alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Research Institute for Biological Safety Problems, RIBSP |
|
Kazakhstan |
2020-09-01 |
2021-04-30 |
NCT04530357, QAZCOV-I/II-01/2020 |
Phase 1/Phase 2 Clinical |
Recruiting |
0 |
8 Months |
244 |
Berik Khairullin, PhD, Gulbanu Sarsenbayeva, MB, Ilyas Kulmagambetov, PhD |
2020-08-31 |
| The Effect of Melatonin and Vitamin C on COVID-19 |
Coronavirus disease 19 infection |
ascorbic acid alone, melatonin alone |
|
Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Lancaster General Hospital |
|
US |
2020-09-01 |
2021-12-01 |
2020-68, NCT04530539 |
Phase Not Applicable |
Not yet recruiting |
0 |
15 Months |
150 |
Ca F, Corey Fogleman, Tawnya Vernon |
2020-08-31 |
| A phase I clinical trial of DIOS-CoVax2 for the potential treatment of COVID-19 infection |
Coronavirus disease 19 infection |
DIOS-CoVax2 alone |
|
|
DIOSynVax Ltd, University of Cambridge |
Technology Strategy Board, University Hospital Southampton NHS Foundation Trust |
UK |
|
|
|
Phase 1 Clinical |
Planned |
1 |
|
|
|
2020-08-31 |
| Phase I Trial of a Recombinant SARS-CoV-2 Vaccine (Sf9 Cell) |
Coronavirus disease 19 infection |
Sf9 Cell alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry |
Jiangsu Province Centers for Disease Control and Prevention |
West China Hospital |
China |
2020-08-28 |
2021-08-28 |
JSVCT098, NCT04530656 |
Phase 1 Clinical |
Not yet recruiting |
1 |
12 Months |
168 |
Fengcai Zhu, Doctor, Siyue Jia, PhD |
2020-08-31 |
| SENTINEL: Selective Estrogen Modulation and Melatonin in Early COVID-19 |
Coronavirus disease 19 infection |
melatonin plus toremifene |
Estrogen receptor modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cleveland Clinic Foundation |
|
US |
2020-09-30 |
2021-09-30 |
20-842, NCT04531748, SENTINEL |
Phase 2 Clinical |
Not yet recruiting |
1 |
12 Months |
390 |
Kylie Phillips, Reena Mehra, MD, Samantha Wells |
2020-08-31 |
| Coronavirus-Induced Acute Kidney Injury: Prevention Using Urine Alkalinization |
Coronavirus disease 19 infection, Renal injury |
sodium bicarbonate alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
West Virginia University |
|
US |
2020-08-31 |
2021-03-31 |
NCT04530448, WVU PROTOCOL #2005006707 |
Phase 4 Clinical |
Not yet recruiting |
1 |
7 Months |
40 |
Ankit Sakhuja, Ankit Sakhuja, MD, Lisa Fornaresio, PhD |
2020-08-31 |
| Effects of Sevoflurane on Extravascular Lung Water and Pulmonary Vascular Permeability in Patients With ARDS |
Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure |
AnaConDa-S, Sedana Medical alone, remifentanil plus sevoflurane |
Opioid receptor mu agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hopital de Bicetre |
|
France |
2020-11-30 |
2022-11-30 |
BICETREH, NCT04530188 |
Phase 3 Clinical |
Not yet recruiting |
1 |
24 Months |
68 |
Christopher Lai, principal investigator, Christopher lai, MD, Xavier Monnet, MD, PhD |
2020-08-31 |
| Efficacy of Sofosbuvir Plus Ledipasvir in Egyptian Patients With COVID-19 Compared to Standard Treatment |
Coronavirus disease 19 infection, Viral pneumonia |
Variable regimens including ceftriaxone , enoxaparin sodium , methylprednisolone , sofosbuvir + ledipasvir |
Low molecular weight heparin |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
|
|
Egypt |
2020-04-15 |
2020-07-23 |
14, NCT04530422 |
Phase 3 Clinical |
Completed |
1 |
3 Months |
250 |
Mohamed Abdelsalam El-Gohary |
2020-08-31 |
| Cytokine Status of Covid-19 Patients |
Coronavirus disease 19 infection, Lymphocytopenia, Respiratory failure |
flow cytometry alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Istanbul Training and Research Hospital |
|
Turkey |
2020-09-01 |
2020-10-15 |
COVID CYTOKINE, NCT04531345 |
Phase Not Applicable |
Not yet recruiting |
1 |
1 Month |
50 |
Tahir Talat Yurttas, MD, Ufuk Oguz Idiz, Assoc. Prof |
2020-08-31 |
| CORE Study COVID-19 |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Instituto D'Or de Pesquisa |
|
Switzerland, UK, Brazil |
2020-03-02 |
2021-09-30 |
29496920.8.0000.5262, NCT04531202 |
Phase Not Applicable |
Recruiting |
3 |
18 Months |
2000 |
Fernando Bozza, phD |
2020-08-31 |
| COVID-19 In-vitro Diagnostic Test and Androgen Receptor Gene Expression |
Coronavirus disease 19 infection |
COVID-19 androgen sensitivity test alone |
|
Healthy volunteers accepted, Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of California Irvine |
Applied Biology Inc |
US |
2020-08-13 |
2021-08-31 |
2020-5907, NCT04530500 |
Phase Not Applicable |
Recruiting |
2 |
12 Months |
200 |
Natasha Mesinkovska, MD, PhD |
2020-08-31 |
| NEBUHEPA: Nebulized Heparin in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) |
Coronavirus disease 19 infection, Inflammatory disease, Lung disease, Viral pneumonia |
enoxaparin sodium plus heparin sodium |
Low molecular weight heparin |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Clinica San Camilo |
|
Argentina |
2020-06-01 |
2021-06-01 |
CSANCAMILO, NCT04530578, NEBUHEPA |
Phase 4 Clinical |
Recruiting |
1 |
12 Months |
200 |
ALICIA B VILASECA, DR, RUBEN F BARBERA, DR, Ruben F Barbera, DR |
2020-08-31 |
| Defibrotide Therapy for SARS-CoV2 (COVID-19) Acute Respiratory Distress Syndrome (ARDS) |
Coronavirus disease 19 infection, Lung disease, Respiratory distress syndrome, Viral pneumonia |
defibrotide (iv, veno-occlusive disease), Gentium alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
University of Michigan |
Jazz Pharmaceuticals plc |
US |
2020-09-30 |
2021-07-31 |
HUM00182089, NCT04530604 |
Phase 1 Clinical |
Not yet recruiting |
1 |
10 Months |
12 |
Gregory Yanik, MD, Mary Maliarik, PhD |
2020-08-31 |
| A trial to evaluate adjuvanted peptide vaccine (microsphere formulation, COVID-19), University of Saskatchewan/VIDO-InterVac/ZYUS Life Sciences for the prevention of COVID-19 |
Coronavirus disease 19 infection |
adjuvanted peptide vaccine (microsphere formulation, COVID-19), University of Saskatchewan/VIDO-InterVac/ZYUS Life Sciences alone |
|
|
VIDO-InterVac |
Canadian Government |
|
2020-12-31 |
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-08-31 |
| COVIDRIC: COVID-19 in Rheumatic Inflammatory Diseases Under Immuno-suppressive Drugs |
Coronavirus disease 19 infection, Rheumatoid arthritis, Spondylarthritis |
immuno-suppressive drug therapy alone, serological test alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital, Montpellier |
|
France |
2020-10-20 |
2024-07-31 |
COVIDRIC, NCT04530682, RECHMPL20_0409, UF8074 |
Phase Not Applicable |
Not yet recruiting |
1 |
45 Months |
5000 |
Jacques MOREL, MD, PhD |
2020-08-31 |
| COVID-19 severity in Elderly people aged > 60 years |
Coronavirus disease 19 infection |
|
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sri Ramachandra Institute of Higher Education and Research |
|
India |
2020-08-30 |
|
CTRI/2020/08/027435 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
200 |
Dr Viswanathan P |
2020-08-29 |
| A Survey to Assess the Impact of the COVID-19 Pandemic and Resultant Lockdown Measures on Ongoing Clinical Trials in India |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
|
|
India |
2020-09-06 |
|
CTRI/2020/08/027420, Survey-IND-01-2020 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
130 |
Jayanti Gupta, Rakesh Dadhania |
2020-08-31 |
| A case report to evaluate the efficacy of methylprednisolone in patients with immune-related pneumonitis and COVID-19 infection |
Coronavirus disease 19 infection, Pneumonia |
methylprednisolone alone |
|
|
Sociedade Beneficente Israelita Brasileira Hospital Albert Einsten |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
2 |
|
2020-08-30 |
| Prevalence of and Factors Associated with Burnout among Philippine Radiation Oncology Residents During the COVID-19 Pandemic |
Coronavirus disease 19 infection |
|
|
|
Philippine General Hospital |
|
Philippines |
2020-07-26 |
2020-08-09 |
PHRR200820-002847 |
Phase Not Applicable |
Completed |
1 |
|
|
Aedrian A. Abrilla, Johanna Patricia Adevoso-Cañal, MD, MHA, MSc, Jose Miguel C. Callueng, MD |
2020-08-31 |
| Herd immunity level to COVID-19 as an indicator of the epidemic progression in Thailand |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
HRH Princess Chulabhorn College of Medical Science, Chulabhorn Royal Academy |
|
Thailand |
2020-07-07 |
|
TCTR20200822003 |
Phase Not Applicable |
Recruiting |
1 |
|
15000 |
Chirayu Auewarakul |
2020-08-29 |
| Offline versus online presentation: benefits and challenges during covid pandemic |
Coronavirus disease 19 infection |
Offline presentation alone, Online presentation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Manipal Academy of Higher Education |
Kasturba Medical College, Manipal |
India |
2020-09-15 |
|
CTRI/2020/08/027418 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
225 |
Vijetha Shenoy Belle |
2020-08-29 |
| Covid-19 with hypertension is responsible for death of patients |
Coronavirus disease 19 infection, Hypertension |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Gujarat Cancer Society Medical college hospital and research centre |
|
India |
2020-08-31 |
|
CTRI/2020/08/027407 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
200 |
Dr Mahipalsinh Raol |
2020-08-31 |
| A retrospective assessment of risk factors for COVID- 19 in health care workers |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Lok Nayak Hospital, Maulana Azad Medical College |
|
India |
2020-09-07 |
|
CTRI/2020/08/027403 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
90 |
DrSukhyanti Kerai |
2020-08-29 |
| Seroprevalence surveillance of covid-19 among population in Johar- 2020 |
Coronavirus disease 19 infection |
|
|
|
|
|
Malaysia |
2020-09-01 |
|
NMRR-20-1814-55673 |
Phase not specified |
Status not specified |
1 |
|
|
Dr Jeyanthini a/p Sathasivam |
2020-08-30 |
| A retrospective study to evaluate cumulative incidence of Covid-19 and its treatment outcome, mortality and associated risk factors in lung cancer patients |
Coronavirus disease 19 infection, Lung tumor |
azithromycin plus hydroxychloroquine |
|
|
Hospital Universitario Infanta Leonor |
|
Spain |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
320000 |
|
2020-08-30 |
| Realtion of Catalytic iron and Hepcidin with Poor Outcomes in COVID-19 patients |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
KEM Hospital and Research Center |
|
India |
2020-09-07 |
|
CTRI/2020/08/027419 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
49 |
Dr Vipul Chakurkar |
2020-08-31 |
| An observational, retrospective study on the association between the use of angiotensin-converting enzyme inhibitors/angiotensinogen receptor blockers and in-hospital mortality of hypertensive patients diagnosed with COVID-19 pneumonia |
Coronavirus disease 19 infection, Hypertension, Viral pneumonia |
angiotensin-converting enzyme inhibitors alone, angiotensinogen receptor blockers alone |
|
|
Saglik bilimleri universtesi |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
74 |
|
2020-08-28 |
| S-Nitrosylation Therapy of COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
S-nitrosothiol alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Japanese Ancestry |
University Hospitals of Cleveland |
Case Western Reserve University |
US |
2020-10-31 |
2021-04-30 |
NCT04528771, STUDY20200453 |
Phase 1b Clinical |
Not yet recruiting |
1 |
6 Months |
21 |
James Reynolds, PhD, Olivia Giddings, MD, Rana Hejal, MD, Robert Schilz, DO, PhD |
2020-08-28 |
| A Case Report of Thrombosis and Bleeding as presentation of COVID-19 infection with polycythemia vera |
Bleeding, Coronavirus disease 19 infection, Polycythemia vera |
|
|
|
Sarawak General Hospital |
|
Malaysia |
2020-08-25 |
|
NMRR-20-1803-56251 |
Phase not specified |
Status not specified |
1 |
|
|
Dr Chow Lai Chee |
2020-08-29 |
| The technical specification of precise drug therapy and the systematic study of novel Coronavirus inactivation procedure for biological samples |
Coronavirus disease 19 infection |
genetic testing alone |
|
|
Shanghai Jiao Tong University |
|
China |
2020-10-01 |
2021-09-30 |
ChiCTR2000037078 |
Phase 0 Clinical |
Not yet recruiting |
1 |
12 Months |
100 |
guorong fan, zhenghua wu |
2020-08-31 |
| IVERCORCOVID19: Ivermectin to Prevent Hospitalizations in COVID-19 |
Coronavirus disease 19 infection |
ivermectin alone |
Chloride channel modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Institute of Cardiology of Corrientes |
|
Argentina |
2020-08-19 |
2021-01-31 |
IVERCORCOVID19, IVERCORCOVID19MSPICC, NCT04529525 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
5 Months |
500 |
Angelina Bobadilla, Dra, Antonia Aquino, Claudia Campias, Diego Farizano, Evangelina Chaparro Campias, Fabian Plano, Dr, Fernanda Medina, Fernando Achinelli, Dr, Gerardo Andino, Hector A Gugliermone, Jorge Ojeda, Dr, Julio Vallejos, Dr, Maria Bangher, Dra, Natalia E Ruiz Diaz, Pablo Kawerin, Rodrigo Zoni, Dr, Silvina Dellamea, Silvina Villamandos, Dra, Victor Flores |
2020-08-28 |
| Our experience with emergency ophthalmic surgery at Hospital Kuala Lumpur (HKL) during the COVID-19 pandemi |
Coronavirus disease 19 infection, Ocular disease |
|
|
|
Hospital Kuala Lumpur |
|
Malaysia |
2020-08-20 |
2020-12-31 |
NMRR-20-1790-56127 |
Phase not specified |
Status not specified |
1 |
4 Months |
|
Dr Seow Shu Yee |
2020-08-31 |
| Application of IL-18/IL-18BP in diagnosis and treatment of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection |
IL-18BP antagonist therapy alone |
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shanghai Public Health Clinical Center |
|
China |
2020-10-30 |
2022-10-30 |
ChiCTR2000036661 |
Phase 0 Clinical |
Not yet recruiting |
1 |
24 Months |
30 |
Mingquan Guo |
2020-08-31 |
| Palliative care expertise as an integral part of pandemic management (COVID-19) |
Coronavirus disease 19 infection |
|
|
|
Universitätsklinikum Freiburg, Klinik für Palliativmedizin |
|
Germany |
2020-05-29 |
|
299/20, DRKS00022473 |
Phase Not Applicable |
Recruiting |
1 |
|
30 |
Katharina Seibel |
2020-08-28 |
| Establishment of imaging diagnostic models for novel coronavirus pneumonia (COVID-19) and related brain injury based on artificial intelligence |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
Huashan Hospital, Shanghai shen-kang hospital clinical development center |
|
China |
2020-10-01 |
2022-09-30 |
ChiCTR2000036849 |
Phase 0 Clinical |
Not yet recruiting |
1 |
24 Months |
5000 |
Bo Yin |
2020-08-31 |
| Multi-center, Randomized, Double-Blind and Placebo-Controlled Clinical Trial on the Efficacy and Safety of Jinhua Qinggan Granules (JHQG) for the Treatment of COVID-19 Patient |
Coronavirus disease 19 infection, Viral pneumonia |
Jinhua Qinggan Granules alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Beijing Hospital of Traditional Chinese Medicine affiliated to Capital Medical University, University Of Karachi |
|
Pakistan |
2020-04-24 |
2021-04-30 |
ChiCTR2000036871, ChiMCTR2000003697 |
Phase 4 Clinical |
Not yet recruiting |
2 |
12 Months |
|
Prof. Dr M. Raza Shah T.I./Liu Qing Quan, Xin Li |
2020-08-31 |
| Convalescent Plasma for Treating Patients With COVID-19 Pneumonia Without Indication of Ventilatory Support |
Coronavirus disease 19 infection, Viral pneumonia |
convalescent plasma alone, standard treatment alone |
|
|
Instituto D'Or de Pesquisa |
Hospital do Coracao |
Brazil |
2020-08-18 |
2020-12-31 |
34651120.8.0000.5249, NCT04528368 |
Phase 2 Clinical |
Recruiting |
1 |
4 Months |
60 |
Abel Costa Neto, MD, Eduardo M Rego, MD, PhD |
2020-08-28 |
| A case report of 18F-fluorodeoxyglucose uptake in patient with asymptomatic severe acute respiratory syndrome coronavirus 2 (coronavirus disease 2019) referred to positron emission tomography/computed tomography for non small cell lung cancer restaging |
Coronavirus disease 19 infection, Non-small-cell lung cancer, SARS coronavirus infection |
18F-fluorodeoxyglucose alone, Positron emission tomography/computed tomography alone |
|
Male |
University of Turin |
|
Italy |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
1 |
|
2020-08-29 |
| Presentation, Clinical Course and Patterns of Myocardial Damage Due to Viral Myocarditis |
Adenovirus infection, Coronavirus disease 19 infection, Enterovirus infection, Heart injury, Hepatitis B virus infection, Hepatitis C virus infection, Myocarditis, Parvovirus infection |
12 lead ECG alone, ELIZA alone, PCR alone, cardiac MRI alone, coronary angiography alone, echocardiography alone, endomyocardial biopsy alone, immunohistochemistry alone, nucleic acid extraction alone, quantitative real-time PCR alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assiut University |
|
Egypt |
2020-09-01 |
2021-03-01 |
NCT04527835, VIRAL MYOCARDITIS |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
18 |
Amr Elbadry, lecturer, Amr yousif, professor, Ayman khairy, assistant professor, Ayman khairy, professor, Shery Asaad, Resident, Shery Asaad, resident, Shery Refaat Asaad |
2020-08-28 |
| QUICK study: A multicenter, retrospective, longitudinal, observational study about Quarantine and social Isolation for COVID-19 and its impact on Kawasaki disease |
Adenovirus infection, Coronavirus disease 19 infection, Gastrointestinal infection, Herpesvirus type 6 infection, Influenza virus infection, Kawasaki disease, Metapneumovirus infection, Respiratory syncytial virus infection, Respiratory tract infection, Skin infection, Streptococcus pyogenes infection |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Japanese Ancestry |
Fukuoka Children's Hospital, Kawasaki disease center |
|
Japan |
2020-06-01 |
2020-08-10 |
QUICK study, UMIN000041579 |
Phase Not Applicable |
No longer recruiting |
5 |
2 Months |
4500 |
Kenji Furuno, Toshiro Hara |
2020-08-31 |
| Development of Ethical and Operational Guidelines for the Delivery of Surgical Care in a COVID-19 Referral Hospital |
Coronavirus disease 19 infection |
surgical care alone |
|
|
Philippine General Hospital |
|
Philippines |
2020-06-01 |
2020-08-01 |
PHRR200820-002855 |
Phase Not Applicable |
No longer recruiting |
1 |
2 Months |
|
Alvin B. Caballes, MD, MDE, MPP, Brent Andrew G. Viray, MD, MPM-HSD, Claudine Lukban, MD, Marie Carmela Lapitan, Maureen Villanueva, MD, Samantha Siahetong, MD |
2020-08-31 |
| Use of emergency medical services: experience 100 days after first case of COVID-19 |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Khon Kaen University |
|
Thailand |
2020-08-21 |
|
TCTR20200822002 |
Phase Not Applicable |
Recruiting |
1 |
|
545 |
Korakot Apiratwarakul |
2020-08-28 |
| THINC: Evaluation of the Efficacy and Safety of Treatments for Patients Hospitalized for COVID-19 Infection Without Signs of Acute Respiratory Failure, in Tunisia |
Bronchitis, Coronavirus disease 19 infection, Lower respiratory tract infection, Respiratory failure, Viral pneumonia |
usual standard treatment alone, Variable regimens including azithromycin , doxycycline hyclate , hydroxychloroquine , zinc |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Abderrahmane Mami Hospital |
Datametrix AG, Eshmoun Clinical Research Centre |
Tunisia |
2020-05-15 |
2020-07-15 |
ECC2020-05, NCT04528927, THINC |
Phase 3 Clinical |
Terminated |
1 |
2 Months |
|
Dr Jalila Ben Khelil |
2020-08-28 |
| PRESAGE: Study of Seroprevalence Vis-a-vis SARS-CoV2 and Correlation With Clinical Forms of COVID-19 in Patients Followed in Pneumology in the Cluster Area of the Grand-Est Region (Strasbourg University Hospital) |
Coronavirus disease 19 infection, Respiratory failure |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hopitaux Universitaires de Strasbourg |
|
France |
2020-09-30 |
2022-12-31 |
7879, NCT04528901, PRESAGE |
Phase Not Applicable |
Not yet recruiting |
1 |
27 Months |
1080 |
Celine MASCAUX |
2020-08-28 |
| Response of Korean Medicine Hospital to COVID-19 |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted |
Jaseng Hospital of Oriental Medicine |
Jaseng Medical Academy |
South Korea |
2020-06-10 |
2020-08-10 |
JMA-CT-2020-01, NCT04529447 |
Phase Not Applicable |
Completed |
1 |
2 Months |
485 |
Jinho Lee, KMD, Ph.D. |
2020-08-28 |
| EARSATS-19: In-ear Measurement of Blood Oxygen Saturation in COVID-19 Follow-up |
Coronavirus disease 19 infection, Lung disease |
ear plug type pulse oximeter probe alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Imperial College London |
|
UK |
2020-08-26 |
2020-08-26 |
285603, EARSATS-19, NCT04529408 |
Phase Not Applicable |
Recruiting |
1 |
|
60 |
Cheuk F Wong, Nicholas Peters, MD, Patrik Bachtiger, Patrik Bachtiger, MBBS |
2020-08-31 |
| An FDA expanded access programm/compassionate use program for bucillamine in COVID-19 |
Coronavirus disease 19 infection |
repurposed formulation of bucillamine (gout/cystinuria/Wilson disease/influenza/COVID-19), Revive Therapeutics alone |
Xanthine oxidase inhibitor |
|
Revive Therapeutics Ltd |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-08-28 |
| Role of Siddha medicine in the management of Covid-19 positive patients |
Coronavirus disease 19 infection |
Variable regimens including adathodai mangapu , ammakura choornam , bramhananda bairavam , kapa sura kudineer , thalasathy vadagam |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Siddha Central Research Institute |
|
India |
2020-09-03 |
|
CTRI/2020/08/027397 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
20 |
DRSTHILLAIVANAN |
2020-08-31 |
| A phase III clinical study to assess CT-P59 in the treatment of patients with moderate-to-severe SARS-CoV-2 infection |
Coronavirus disease 19 infection |
CT-P59 alone |
COVID19 Spike glycoprotein inhibitor, Moesin modulator |
|
Celltrion Healthcare Co Ltd |
|
|
2020-12-31 |
|
|
Phase 3 Clinical |
Planned |
0 |
|
|
|
2020-08-28 |
| Mental health of pregnant women Covid-19 pandemic |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs) |
All India Institute of Medical Sciences |
|
India |
2020-09-03 |
|
CTRI/2020/08/027396 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Dr Vidushi Kulshrestha |
2020-08-31 |
| A phase I clinical study to assess safety, tolerability, efficacy, pharmacokinetics and immunogenicity of CT-P59 in patients with mild symptoms of SARS-CoV-2 infection |
Coronavirus disease 19 infection |
CT-P59 alone |
COVID19 Spike glycoprotein inhibitor, Moesin modulator |
|
Celltrion Healthcare Co Ltd |
|
South Korea |
2020-08-26 |
|
|
Phase 1 Clinical |
Recruiting |
1 |
|
|
|
2020-08-28 |
| TRACERx Renal CAPTURE: TRACERx Renal CAPTURE Sub-study |
Coronavirus disease 19 infection, Renal cell carcinoma |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The Royal Marsden NHS Trust |
The Francis Crick Institute |
UK |
2012-02-05 |
2023-09-01 |
CCR 3723, NCT03226886, TRACERx Renal CAPTURE |
Phase Not Applicable |
Recruiting |
4 |
138 Months |
360 |
Dr Maxine Tran, Dr Sarah Rudman, Ellie Carlyle, Prof William Drake, Samra Turajlic, Steve Leung |
2020-08-28 |
| Study of Radiological Imaging in COVID Patients |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sri Ramachandra University |
|
India |
2020-09-01 |
|
CTRI/2020/08/027395 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1000 |
Dr Swathy Moorthy |
2020-08-28 |
| Assessment of response of ivermectin on virological clearance in COVID-19 patients |
Coronavirus disease 19 infection |
ivermectin alone |
Chloride channel modulator |
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Maulana Azad Medical College |
|
India |
2020-09-02 |
|
CTRI/2020/08/027394 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
56 |
ROMIT SAXENA |
2020-08-31 |
| Evaluating an Online Adjunctive Support Following Intensive Services (OASIS) Strategy for Youth With Selective Mutism |
Anxiety disorder, Coronavirus disease 19 infection |
remote caregiver training alone, remote intensive group behavioral treatment alone |
|
Preschool Children (2-5 yrs), Children (6-12 yrs) |
Florida International University |
|
US |
2020-03-06 |
2020-12-01 |
20-0010, NCT04291638 |
Phase Not Applicable |
No longer recruiting |
1 |
8 Months |
11 |
Natalie Hong, M.S. |
2020-08-29 |
| Long term follow up of patients with COVID 19 |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
General hospital of sestri levante |
|
China |
2020-06-22 |
2020-10-31 |
ChiCTR2000036982 |
Phase Not Applicable |
Not yet recruiting |
1 |
4 Months |
250 |
Nicolini Antonello, Russo giuseppe |
2020-08-31 |
| Physiotherapy Practices for patients with COVID-19- A National Survey |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Sri Ramachandra Institute of Higher Education and Research |
|
India |
2020-08-28 |
|
CTRI/2020/08/027393 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
250 |
Narasimman Swaminathan |
2020-08-31 |
| Evaluation of the Nextdoor KIND Challenge |
Coronavirus disease 19 infection, Psychiatric disorder |
KIND Challenge alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Swinburne University of Technology |
Brigham Young University, University of Manchester, University of Sydney |
Australia |
2020-07-07 |
2020-12-31 |
NCT04398472, ND01 |
Phase Not Applicable |
Not yet recruiting |
1 |
5 Months |
9000 |
Michelle Lim |
2020-08-28 |
| Mi-CARE: Role of Midwifery Continuity of Care in Reducing Health Inequalities |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Female, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Bournemouth University |
University Hospital Southampton NHS Foundation Trust |
UK |
2020-10-01 |
2022-03-18 |
19/20/IRAS/CC, 262369, 45534, Mi-CARE, NCT04524286 |
Phase Not Applicable |
Not yet recruiting |
1 |
17 Months |
60 |
Charlotte Clayton, Suzy Wignall |
2020-08-31 |
| Anosmia and/or Ageusia and Early Corticosteroid Use |
Ageusia, Coronavirus disease 19 infection, Dysomia |
dexamethasone alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
ClinAmygate |
|
|
2020-08-30 |
2020-12-15 |
NCT04528329, PR0013 |
Phase 4 Clinical |
Not yet recruiting |
0 |
3 Months |
300 |
|
2020-08-31 |
| Clinical Trial Evaluating the Efficacy and Safety of Favipiravir in Moderate to Severe COVID-19 Patients |
Coronavirus disease 19 infection, Dyspnea, Respiratory distress syndrome |
favipiravir alone, supportive care alone |
RNA polymerase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Dr Reddy's Laboratories Ltd |
|
Kuwait |
2020-08-20 |
2021-01-31 |
CVD-04-CD-001, NCT04529499 |
Phase 3 Clinical |
Recruiting |
2 |
5 Months |
780 |
Carmela Fritz, Mohammad S. M. D. AlHumaidan, MBBS, Sagar Munjal, MD, MS, Salman Khalifa Al-Sabah, MD, Sarah Al Youha, Srinivas Shenoy, MD, Sulaiman Al Mazeedi |
2020-08-31 |
| GRAd-COV2 Vaccine Against COVID-19 |
Coronavirus disease 19 infection |
GRAd-COV2 alone |
COVID19 Spike glycoprotein modulator |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
ReiThera Srl |
Istituto Nazionale Per Le Malattie Infettive "Lazzaro Spallanzani", Ministero per l Universita e la Ricerca Scientifica e Tecnologica |
Italy |
2020-08-10 |
2021-07-31 |
NCT04528641, RT-COV-2 |
Phase 1 Clinical |
Recruiting |
4 |
11 Months |
90 |
Antonella Folgori, CEO, Federica Mori, MGR, Simone Lanini, Simone Lanini, DR, Stefano Milleri, Medical Director |
2020-08-31 |
| COVID-pO2-RAAS: COVID-19 : Transcutaneous pO2 and pCO2 as Predictive Factors for Acute Respiratory Destress Syndrome in Patients Affected With SARS-Cov-2 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
PeriFlux system 5000 (Perimed) alone, pulse oximetry alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Erasme Hospital |
|
Belgium |
2020-10-04 |
2023-05-04 |
COVID-pO2-RAAS, NCT04524156, P2020/238 |
Phase Not Applicable |
Not yet recruiting |
1 |
31 Months |
100 |
Nora Bahhodh, Sofia Morra, MD |
2020-08-31 |
| OUR-Project: OUR Stress/Emotion Management for Black/African American Women With Hypertension |
Acute stress disorder, Coronavirus disease 19 infection, Hypertension |
Enhanced Co-Created Health Education InterventioN (eCo-CHIN) alone |
|
Healthy volunteers accepted, Female, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), African Ancestry |
Ohio State University |
|
US |
2020-09-14 |
2022-01-30 |
2020B0182, NCT04526145, OUR-Project |
Phase Not Applicable |
Not yet recruiting |
1 |
16 Months |
30 |
Kathy D Wright, PhD, RN, Rashmeet Reen, PhD |
2020-08-28 |
| ICOPain: The influence of the Covid-19 pandemic on pain and pain related disability in chronic pain patients – an explorative study |
Coronavirus disease 19 infection, Pain |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universitatsklinikum Essen |
Stiftung Universitätsmedizin Essen |
Germany |
2020-04-20 |
|
20-9271-BO, DRKS00022395, ICOPain, U1111-1250-5064 |
Phase Not Applicable |
No longer recruiting |
1 |
|
197 |
Ulrike Bingel |
2020-08-28 |
| MSC-based Therapy in COVID-19-associated Acute Respiratory Distress Syndrome |
Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure, Viral pneumonia |
mesenchymal stromal cell-based therapy alone, standard care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Instituto D'Or de Pesquisa |
|
Brazil |
2020-07-01 |
2020-10-31 |
NCT04525378, PCL02/2020 |
Phase 1 Clinical |
Recruiting |
1 |
4 Months |
20 |
Andre Gobatto, MD PHD, Bruno SF Souza, MD PHD |
2020-08-28 |
| A clinical trial of ASX-100 for the treatment of Coronavirus disease 19 infection associated Respiratory distress syndrome |
Coronavirus disease 19 infection, Respiratory distress syndrome |
ASX-100 alone |
|
|
Asalyxa Bio, University of Michigan |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-08-28 |
| COVID-19 Pandemic and Parents of Disabled Children |
Coronavirus disease 19 infection |
questionnaire alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Gaziosmanpasa Taksim Research and Education Hospital |
|
Turkey |
2020-07-05 |
2020-09-15 |
105, NCT04525742 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
190 |
Berrin Huner, Speacilist, Berrin Huner, Specialist, Berrin Hüner, Ebru Yilmaz Yalcinkaya, Professor, Ebru Yilmaz Yalçınkaya, Professor, Evrim Karadağ Saygı, Professor, Nalan Çapan, Professor, Resa Aydin, Professor, Sibel Bektas, Professor, Özden Özyemisçi Taşkıran, Professor |
2020-08-31 |
| Assocation Between In-person Instruction and COVID-19 Risk |
Coronavirus disease 19 infection |
in-person instruction alone, online instruction alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Oslo and Akershus University College of Applied Sciences |
Norwegian Institute of Public Health |
Norway |
2020-09-30 |
2020-12-31 |
172155, NCT04529421 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
70000 |
Arnfinn Helleve, PhD, Atle Fretheim, PhD, Gro Jamtvedt, PhD |
2020-08-31 |
| Healthy Volunteer COVID-19 Antibody Testing Study |
Coronavirus disease 19 infection |
ARIA COVID-19 IgG/IgM Rapid Test (CTK Biotech, Inc) alone, enzyme-linked immunosorbent assay alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Royal Free Hospital NHS Foundation Trust |
|
UK |
2020-09-01 |
2021-04-30 |
134035, NCT04529460 |
Phase Not Applicable |
Not yet recruiting |
1 |
8 Months |
200 |
Daniel Martin, MB ChB, Helder Filipe |
2020-08-31 |
| A phase I trial to evaluate MAN-19 to treat complications caused by COVID-19 |
Coronavirus disease 19 infection |
MAN-19 alone |
|
|
Q BioMed Inc |
Canadian Government, German Government |
|
2021-02-28 |
|
|
Phase 1 Clinical |
Planned |
0 |
|
|
|
2020-08-28 |
| Study of the Safety and Efficacy of STI-5656 (Abivertinib Maleate) in Subjects Hospitalized Due to COVID-19 |
Coronavirus disease 19 infection |
abivertinib alone, standard of care alone |
Btk tyrosine kinase inhibitor, EGFR gene inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sorrento Therapeutics Inc |
|
US |
2020-09-30 |
2021-05-31 |
BTK-COV-202BR, NCT04528667 |
Phase 2 Clinical |
Not yet recruiting |
1 |
8 Months |
400 |
Mike Royal, MD |
2020-08-28 |
| STAUNCH-19: Steroids and Unfractionated Heparin in Critically Ill Patients With Pneumonia From COVID-19 Infection |
Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia |
Variable regimens including Veracer , enoxaparin sodium biosimilar, Techdow , methylprednisolone (Pfizer) |
Low molecular weight heparin |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Modena and Reggio Emilia |
|
Italy |
2020-09-01 |
2021-07-30 |
NCT04528888, STAUNCH-19, STAUNCH-19-1.1-26-04-20 |
Phase 3 Clinical |
Not yet recruiting |
2 |
10 Months |
210 |
Massimo Girardis, PD, Massimo Girardis, PI, Stefano Busani |
2020-08-31 |
| Project Resurgence Communication Trial |
Coronavirus disease 19 infection |
communication by letter alone, mailed intervention letter alone |
|
|
University of Pennsylvania |
|
US |
2020-06-15 |
2020-07-17 |
843220, NCT04418947 |
Phase Not Applicable |
Completed |
1 |
1 Month |
11120 |
Anne Cappola |
2020-08-28 |
| An observational study to evaluate the association between treatment with heparin and survival in patients with COVID-19 |
Coronavirus disease 19 infection |
heparin alone |
|
|
Guy's & St Thomas' Hospital NHS Trust, King's College London, National Institute for Health Research (NIHR) |
|
Spain |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
1734 |
|
2020-08-28 |
| A case report to evaluate the efficacy of anakinra in patient with COVID-19 infection |
Coronavirus disease 19 infection |
anakinra alone |
Type I IL-1 receptor antagonist |
Male |
Fondazione IRCCS Ca' Granda-Ospedale Maggiore Policlinico |
|
Italy |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
1 |
|
2020-08-30 |
| A phase I clinical trial of EPV-CoV-19 for potential prevention of COVID-19 |
Coronavirus disease 19 infection |
EPV-CoV19 alone |
|
|
EpiVax Inc, EpiVax Therapeutics |
|
|
|
|
|
Phase 1 Clinical |
Planned |
0 |
|
|
|
2020-08-27 |
| TRACE ll Prospective: Outcome in patients undergoing postponed elective surgery during the COVID-19 pandemic |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Amsterdam UMC |
The Netherlands Organisation for Health Research and Development |
Netherlands |
2020-09-01 |
2021-12-31 |
NL8841, TRACE ll Prospective |
Phase Not Applicable |
Not yet recruiting |
1 |
16 Months |
|
Carin Wensing |
2020-08-28 |
| The efficacy of methylprednisolone mini pulse on the treatment of COVID-19 patients admitted to intensive care unit |
Coronavirus disease 19 infection |
Standard treatment alone, methylprednisolone alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ardabil University of Medical Sciences |
|
Iran |
2020-07-10 |
|
IR.ARUMS.REC.1399.206, IRCT20170716035126N4 |
Phase 3 Clinical |
No longer recruiting |
2 |
|
60 |
Afshin Habibzadeh, Dr. Masoud Entezari Asl, Yousef Mohammadi Kebar |
2020-08-28 |
| TRACE ll Retrospective: Outcome in patients undergoing (postponed) surgery during the COVID-19 pandemic |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Maastricht UMC+ |
|
Netherlands |
2020-08-31 |
2020-12-31 |
NL8837, TRACE ll Retrospective |
Phase Not Applicable |
Recruiting |
1 |
4 Months |
14000 |
Carin Wensing |
2020-08-28 |
| A clinical trial of Digid Cantisense SARS-CoV-2 test for COVID-19 infection |
Coronavirus disease 19 infection |
Digid Cantisense SARS-CoV-2 test alone |
|
|
Mainz University Hospital |
|
Germany |
|
|
|
Phase Not Applicable |
Not yet recruiting |
1 |
|
|
|
2020-08-28 |
| Treatment and Prevention of Acute Lung Injury (ALI) in Patients With COVID-19 Infection |
Acute lung injury, Coronavirus disease 19 infection, Inflammatory disease, Viral pneumonia |
daxdilimab alone |
Leukocyte Ig like receptor A4 modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Viela Bio |
|
US |
2020-08-31 |
2021-03-31 |
NCT04526912, VIB7734.P1.S2 |
Phase 1 Clinical |
Not yet recruiting |
1 |
7 Months |
48 |
Daniel Falleroni, Gábor Illei, MD, PhD, MHS |
2020-08-31 |
| COVID-19 Survivorship Registry |
Coronavirus disease 19 infection, Pulmonary heart disease |
MRI alone, chest imaging alone, echocardiography alone, spirometry alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
NYU Langone Health |
|
US |
2020-07-17 |
2023-08-31 |
20-00909, NCT04527315 |
Phase Not Applicable |
Recruiting |
1 |
37 Months |
350 |
Ashley Witzl, Ellen Hada, Rany Condos, MD |
2020-08-31 |
| Efficacy and feasibility of an audio-based mindfulness intervention in reducing anxiety, depression and stress among people with the risk of anxiety and depression during the coronavirus disease 2019 (COVID-19) pandemic in Thailand |
Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression |
audio-guided mindfulness practice program alone, psychoeducation alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Faculty of Medicine Siriraj Hospital, Mahidol University |
|
Thailand |
2020-09-15 |
|
TCTR20200819003 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
70 |
Natee Viravan |
2020-08-29 |
| LF-COVID: Lactoferrin for Prevention of COVID-19 in Health Care Workers |
Coronavirus disease 19 infection |
bovine lactoferrin alone, standard personal protection measure alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Universidad Peruana Cayetano Heredia |
|
Peru |
2020-09-01 |
2021-11-01 |
LF-COVID, NCT04526821, SIDISI 202110 |
Phase 2 Clinical |
Not yet recruiting |
2 |
14 Months |
336 |
Carlos Medina, MD, Eddie Angles, MD, Fernando Mejia, MD, Msc, Jorge Florez, MD, Meylin Aphang, MD, Msc, Theresa J Ochoa, MD, PhD |
2020-08-28 |
| Detecting SARS-CoV-2 in Tears |
Coronavirus disease 19 infection |
IHC staining alone, RT-PCR alone, biological sampling alone, tear collection alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Minnesota |
|
US |
2020-09-30 |
2021-04-30 |
NCT04526769, STUDY00009512 |
Phase Not Applicable |
Not yet recruiting |
1 |
7 Months |
30 |
Corey Miller, Hossein Nazari, MD |
2020-08-28 |
| Study of COVID-19 DNA Vaccine (AG-0302-COVID19) |
Coronavirus disease 19 infection |
AG-0302-COVID19 alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
AnGes MG Inc |
|
Japan |
2020-08-31 |
2021-09-30 |
AG0302-COVID19-JN-01, JapicCTI-205419, NCT04527081 |
Phase 1/Phase 2 Clinical |
Recruiting |
1 |
13 Months |
30 |
AnGes, Inc. Clinical Development |
2020-08-31 |
| ISARIC: Case Fatalities in Hospitalized COVID-19 Patients in the UK |
Coronavirus disease 19 infection |
|
|
|
University of Edinburgh |
ISARIC |
UK |
2020-02-24 |
2020-08-02 |
ISARIC, ISARIC-COVID-CF, NCT04527458 |
Phase Not Applicable |
Completed |
1 |
5 Months |
70000 |
Annemarie B Docherty, Ewen M Harrison, Rachel H Mulholland |
2020-08-28 |
| An observational case report to determine the subacute thyroiditis associated with Covid-19 infection |
Coronavirus disease 19 infection |
hydroxychloroquine alone, prednisolone alone |
|
Female, European Ancestry |
Ankara City Hospital Bilkent |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
1 |
|
2020-08-27 |
| A phase Ib/II, randomized, double-blind, placebo-controlled study to assess the safety and efficacy of alvelestat in adult patients hospitalized with moderate to severe COVID-19 respiratory disease not yet receiving mechanical ventilation |
Coronavirus disease 19 infection, Respiratory disease |
alvelestat alone, standard of care alone |
Leukocyte elastase inhibitor |
|
Mereo BioPharma Group Ltd |
|
US |
2020-08-25 |
|
|
Phase 1/Phase 2 Clinical |
Recruiting |
1 |
|
15 |
Dr. J. Michael Wells |
2020-08-27 |
| CHIP: COVID-19 Health Professional Impact Study |
Coronavirus disease 19 infection |
SARS-CoV-2 antibody test alone |
|
Healthy volunteers accepted |
The Royal Wolverhampton Hospitals NHS Trust |
The University Of Wolverhampton |
UK |
2020-09-10 |
2020-12-31 |
2020COV112, CHIP, NCT04527432 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
3000 |
Lorraine Jacques, Supratik Basu |
2020-08-31 |
| Effect of donkey milk on the new COVID-19 |
Coronavirus disease 19 infection |
candy intake alone, donkey milk intake alone, drug treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Kerman University of Medical Sciences |
|
Iran |
2020-09-05 |
|
IR.KMU.REC.1399.321, IRCT20161108030776N3 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
110 |
Abbas Pardakhty, Haleh Tajadini, Haleh tajadini, Mohadese Kamali |
2020-08-29 |
| IveprofCovid19: Effectiveness and Safety of Ivermectin for the Prevention of Covid-19 Infection in Colombian Health Personnel |
Coronavirus disease 19 infection |
ivermectin alone |
Chloride channel modulator |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Javeriana University |
|
Colombia |
2020-09-07 |
2020-12-16 |
EPI1JAVECALI, IveprofCovid19, NCT04527211 |
Phase 3 Clinical |
Not yet recruiting |
1 |
3 Months |
550 |
Eduar D. Echeverri, Dr., Eduar d Echeverri, Dr., Julian Santaella, PhD |
2020-08-28 |
| Study to Evaluate the Efficacy and Safety of AstroStem-V in Treatment of COVID-19 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
AstroStem-V alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Nature Cell Co. Ltd. |
|
|
2020-12-01 |
2022-04-01 |
ASVP1N2A-US, NCT04527224 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
0 |
16 Months |
10 |
|
2020-08-28 |
| Extremely Premature Births During the Peak of the COVID-19 Pandemic: an International Study of the Active SafeBoosC III Departments |
Coronavirus disease 19 infection, Premature labor |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months) |
Rigshospitalet, Denmark |
|
Denmark |
2020-08-21 |
2020-09-13 |
NCT04527601, SAFEBOOSC COVID-19 ELGAN STUDY |
Phase Not Applicable |
Recruiting |
1 |
|
280 |
Gitte Hahn, MD,PhD, Gorm Greisen, Gorm Greisen, MD, Prof, Marie Isabel Skov Rasmussen, MBBS |
2020-08-28 |
| The Effects of Filter During CPET on WOB and Aerosol Particle Concentrations |
Coronavirus disease 19 infection |
Vyair Vmax (Vyaire medical) alone, cardiopulmonary exercise testing alone, mask with in-line filter alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Rush University Medical Center |
Lundquist Institute |
US |
2020-08-29 |
2020-12-31 |
CPET-001, NCT04526925 |
Phase Not Applicable |
Recruiting |
1 |
4 Months |
10 |
Jie Li, MS, Jie Li, PhD |
2020-08-28 |
| A clinical trial of UNI911for the treatment of Covid-19 |
Coronavirus disease 19 infection |
niclosamide (COVID-19), UNION therapeutics/ Institut Pasteur Korea alone |
S phase kinase associated protein 2 inhibitor |
|
UNION therapeutics |
|
|
|
|
|
Phase not specified |
Planned |
0 |
|
|
|
2020-08-27 |
| Study of Ensifentrine or Placebo Delivered Via pMDI in Hospitalized Patients With COVID-19 |
Coronavirus disease 19 infection |
ensifentrine alone, standard of care alone |
CFTR stimulator, PDE 3 inhibitor, PDE 4 inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Verona Pharma Inc |
Verona Pharma plc |
US |
2020-08-31 |
2021-03-31 |
NCT04527471, RPL554-COV-201 |
Phase 2 Clinical |
Not yet recruiting |
1 |
7 Months |
45 |
Verona Pharma Inc |
2020-08-28 |
| Heat Shock Protein Inhibitor- MPT-0B640 for COVID-19 Infection |
Coronavirus disease 19 infection |
MPT-0B64 alone |
Heat shock protein HSP90 alpha inhibitor, Heat shock protein HSP90 beta inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Joseah Biopharma Co Ltd |
|
|
2020-12-31 |
2021-12-31 |
JO201901-02, NCT04526717 |
Phase 1 Clinical |
Not yet recruiting |
0 |
12 Months |
15 |
Ethan Seah, Haein Kim, JiHye Choe |
2020-08-29 |
| A human trial of SAR-CoV-2 vaccine (recombinant protein, COVID-19)for the prevention of COVID-19 |
Coronavirus disease 19 infection |
SAR-CoV-2 vaccine (recombinant protein, COVID-19), Sichuan University/Zhejiang Teruisi Pharmaceutical/Chengdu Institute of Biological Products alone |
|
|
Sichuan University |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-08-27 |
| COLCOVIDBD: Colchicine in Moderate Symptomatic COVID-19 Patients: Double-Blind, Randomized, Placebo-Controlled Trial to Observe the Efficacy |
Coronavirus disease 19 infection |
colchicine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Dhaka medical college |
|
Bangladesh |
2020-07-14 |
2020-12-31 |
COLCOVIDBD, NCT04527562, U1111-1255-3541 |
Phase 2 Clinical |
Recruiting |
1 |
5 Months |
300 |
Motlabur Rahman, MBBS, FCPS,FACP, Motlabur Rahman, MBBS,FCPS,FACP, Mujibur Rahman, MBBS,MD,FCPS, Ponkaj Datta, MBBS, FCPS |
2020-08-28 |
| CoVIHDis: Differences in Immune Response Among HIV-1-infected Individuals With Previous or Current COVID-19 |
Coronavirus disease 19 infection, HIV-1 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Asociacion para el Estudio de las Enfermedades Infecciosas |
|
Spain |
2020-09-01 |
2021-09-30 |
CoVIHDis, EC 273/20, NCT04526977 |
Phase Not Applicable |
Not yet recruiting |
1 |
13 Months |
90 |
Alejandro Vallejo, PhD, Jose L Casado, PhD |
2020-08-29 |
| A Patient Perspective Survey on Masking or De-Masking the Medical Staff amid COVID-19 Pandemic |
Coronavirus disease 19 infection |
|
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Maroondah hospital |
Box Hill Hospital |
Australia |
2020-03-23 |
|
ACTRN12620000808943, U1111-1256-1499 |
Phase Not Applicable |
Recruiting |
4 |
|
500 |
Dr Aihua Wu |
2020-08-31 |
| LIBERTY: Controlled clinical trial of hydroxychloroquine in the treatment of adult patients with Covid-19 infection in a primary care setting |
Coronavirus disease 19 infection |
Oxiklorin alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Porin kaupunki |
|
Finland |
2020-07-16 |
|
2020-002038-33, LIBERTY, LIBERTY |
Phase 2 Clinical |
Recruiting |
1 |
|
600 |
CRST Oy |
2020-08-29 |
| An Open, Non-comparative Study of the Efficacy and Safety of Aprotinin in Patients Hospitalized With COVID-19 |
Coronavirus disease 19 infection, Lung injury, Viral pneumonia |
Gordox alone, standard of care alone, Gordox plus favipiravir |
RNA polymerase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Aviron Pharma LLC |
|
Russian Federation |
2020-06-11 |
2020-08-31 |
COVID-APR-01, NCT04527133 |
Phase 2 Clinical |
No longer recruiting |
1 |
2 Months |
30 |
Elena Simakina, MD |
2020-08-29 |
| Clinical Course and Treatment of COVID-19 Inpatients in Hospital |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Wissenschaftliches Institut Bethanien e.V. |
|
Germany |
2020-08-01 |
2021-08-31 |
NCT04527497, WI_20-1294 |
Phase Not Applicable |
Recruiting |
1 |
13 Months |
50 |
Anja Pietzke-Calcagnile, Dr., Marcel Treml, Dr., Simon Herkenrath, Winfried Randerath, Prof. Dr. |
2020-08-29 |
| Effect of traditional medicine protocol included Astraglus gossypinus with Ferula assa capsule on improvement of COVID-19 outpatients symptoms |
Coronavirus disease 19 infection |
standard Corona treatment alone, Astragalus gossypinus syrup plus Ferula assafoetida syrup |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kerman University of Medical Sciences |
|
Iran |
2020-08-10 |
|
IR.KMU.REC.1399.275, IRCT20101219005416N3 |
Phase Not Applicable |
Recruiting |
1 |
|
120 |
Abas Pardakhti, Haleh Tajadini |
2020-08-28 |
| Effect of a Brief Mood Training Program on Anxiety and Depression Arising from COVID-19-Related Stress |
Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression |
positive mood training alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
UNSW Sydney |
National Health and Medical Research Council |
Australia |
2020-09-30 |
2021-01-29 |
ACTRN12620000811909p |
Phase Not Applicable |
Not yet recruiting |
9 |
4 Months |
240 |
Prof Richard Bryant |
2020-08-31 |
| A phase I/II clinical trial of injector type GX-19 covid vaccine |
Coronavirus disease 19 infection |
GX-19 alone |
|
|
Gangnam Severance Hospital, Genexine Co Ltd, Severance Hospital |
|
South Korea |
|
|
|
Phase 1/Phase 2 Clinical |
Planned |
2 |
|
|
|
2020-08-31 |
| BRAINSTEM-COV: Brainstem Dysfunction in COVID-19 Critically Ill Patients: a Prospective, Observational Study |
Brainstem disease, Coronavirus disease 19 infection |
electrocardiography alone, electroencephalography alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assistance Publique Hopitaux de Paris |
|
France |
2020-08-31 |
2021-05-31 |
2020-A01559-30, APHP200644, BRAINSTEM-COV, NCT04527198 |
Phase Not Applicable |
Not yet recruiting |
2 |
9 Months |
40 |
Adèle BELLINO, Bertrand HERMANN, MD, PhD, Bertrand HERMANN, MD,PhD, Sarah BENGHANEM, MD |
2020-08-29 |
| PICOV: Influence of Prior Infection With COVID-19 on Occurrence of Influenza-like Illness or Acute Respiratory Infection |
Coronavirus disease 19 infection, Influenza virus infection, Respiratory syncytial virus infection, Respiratory tract infection |
multiplex assay alone, qRT-PCR test alone, serology testing alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sciensano |
Institute of Tropical Medicine, Belgium, Mensura EDPB, Universite Libre de Bruxelles |
Belgium |
2020-09-01 |
2021-05-30 |
NCT04527614, PICOV, PICOV2021 |
Phase Not Applicable |
Not yet recruiting |
1 |
8 Months |
2000 |
Maria Gpossens |
2020-08-28 |
| MSCCOVIDP: Mesenchymal stromal cell (MSC) therapy for COVID-19 pneumonia |
Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia |
bone-marrow derived mesenchymal stromal cells (MSC) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Royal Perth Hospital |
|
Australia |
2020-05-05 |
2020-12-30 |
ACTRN12620000840987, CT-2020-CTN-01580-1 v1, MSCCOVIDP, RGS0000003982, U1111-1254-9427 |
Phase 1 Clinical |
Recruiting |
2 |
7 Months |
10 |
A/Prof Marian Sturm, Dr Ben Carnley |
2020-08-31 |
| A Phase I/II, randomized, placebo-controlled, multicenter study to evaluate the safety and immunogenicity of COVID-19 Vaccine in Healthy Adults |
Coronavirus disease 19 infection |
RBD SARS-CoV-2 HBsAg VLP vaccine alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
ACCELAGEN PTY LTD, Serum Institute of India Ltd |
|
Australia |
2020-08-17 |
2020-11-30 |
ACTRN12620000817943p |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
2 |
3 Months |
280 |
A/Prof Paul Griffin, Mr Greg Plunkett |
2020-08-31 |
| A post-registration, randomized, double-blind, placebo-controlled multicenter clinical study of the efficacy, immunogenicity and safety of the Sputnik V vaccine |
Coronavirus disease 19 infection |
Sputnik V alone |
COVID19 Spike glycoprotein modulator |
|
Gamalei Institute of Epidemiology and Microbiology, Russian Direct Investment Fund |
|
Russian Federation |
|
|
|
Phase 4 Clinical |
Not yet recruiting |
1 |
|
40000 |
|
2020-08-27 |
| COFIT registry: Registry of Covid 19 survivors for Fitness, exercise impairment and exercise Training |
Coronavirus disease 19 infection |
|
|
|
Maxima Medisch Centrum Veldhoven |
|
Netherlands |
2020-08-14 |
2022-08-14 |
COFIT registry, NL8836 |
Phase Not Applicable |
Recruiting |
1 |
24 Months |
200 |
Martijn van Hooff |
2020-08-28 |
| ICU-VR after COVID-19: Intensive Care Unit specific Virtual Reality (ICU-VR) to improve psychological impairments in survivors of COVID-19: a multicenter, randomized, controlled trial |
Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder |
Intensive Care Unit Specific Virtual Reality therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Erasmus University Medical Center Rotterdam |
BeterKeten, Franciscus Gasthuis & Vlietland, Stichting Coolsingel |
|
2020-06-29 |
2021-12-31 |
ICU-VR after COVID-19, NL8835 |
Phase Not Applicable |
Recruiting |
0 |
18 Months |
80 |
Johan Vlake |
2020-08-28 |
| C-SMART (Arm 3): COVID-19 Prevention and Treatment in Cancer.Arm 3: treatment among cancer patients with moderate COVID-19 infection |
Coronavirus disease 19 infection |
IFN-alpha alone, lenzilumab alone, selinexor alone |
Exportin 1 inhibitor, GM-CSF ligand inhibitor, Immunoglobulin G1 modulator, Immunoglobulin kappa modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Peter MacCallum Cancer Centre |
Australian Government |
Australia |
2020-09-01 |
|
ACTRN12620000841976, C-SMART (Arm 3), U1111-1256-8488 |
Phase 3 Clinical |
Not yet recruiting |
5 |
|
126 |
Dr Michelle Yong, Mr Ronan Burder, Prof Monica Slavin |
2020-08-29 |
| Crit-Cov-U: Prospective validation of a proteomic urine test for early and accurate prognosis of critical course complications in patients with SARS-CoV-2 infection |
Coronavirus disease 19 infection |
proteomic urine test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hannover Medical School |
Deutsche Forschungsgemeinschaft (DFG), German Federal Ministry of Education and Research |
Austria, Germany |
2020-08-01 |
|
Crit-Cov-U, DRKS00022495, EK-BR-88/20-1 |
Phase Not Applicable |
Recruiting |
2 |
|
1000 |
Heiko von der Leyen, Joachim Beige |
2020-08-28 |
| Prediction Models for Diagnosis and Prognosis of Severe COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure, Shock, Viral pneumonia |
artificial intelligence model alone, computed tomography alone |
|
|
Second Affiliated Hospital ZheJiang University College of Medicine |
|
China |
2020-02-20 |
2020-08-20 |
2020-12020001231, NCT04525287 |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
1000 |
Luopei Wei, Minming Zhang, PHD |
2020-08-28 |
| Methylene Blue in COVID-19 |
Coronavirus disease 19 infection, Respiratory failure |
corticosteroid therapy alone, Metiblo, Oterop company plus lopinavir + ritonavir |
HIV protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shiraz University of Medical Sciences |
|
Iran |
2020-08-15 |
|
IR.SUMS.REC.1399.016, IRCT20090701002113N2 |
Phase 3 Clinical |
Recruiting |
2 |
|
260 |
Jamshid Roozbeh, Siavash Gholami, Yunos Ghasemi |
2020-08-29 |
| Wide Scale Monitoring for Acute Respiratory Infection Using a Mobile-based Study Platform |
Coronavirus disease 19 infection, Influenza virus infection, Respiratory tract infection |
mobile-based study platform app (Google Inc) alone, wide scale monitoring alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Boston Children's Hospital |
Google Inc |
US |
2020-09-30 |
2021-09-30 |
IRB-P00036213, NCT04525118 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
100000 |
Emily Cohn, MPH, John Brownstein, Kara Sewalk, MPH |
2020-08-29 |
| A Phase I Study of the EmitBio RD19 Device to Prevent SARS-CoV-2 and COVID-19 |
Coronavirus disease 19 infection |
EmitBio RD19 alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
KNOW Bio LLC |
M3-Wake Research Associates Carolina Phase I Clinical Trial Unit, TAB Clinical |
US |
2020-08-31 |
2020-10-01 |
NCT04525976, RD19-01-3Q20 |
Phase Not Applicable |
Not yet recruiting |
1 |
1 Month |
25 |
Aubrey Farray, John G McNeil, MD MPH PHD, Lisa Cohen, DO, Lisa Eckert, PA, Lynn A Bagylos, MSN |
2020-08-28 |
| Hand Sanitizer Effects on the Skin Barrier |
Atopic dermatitis, Coronavirus disease 19 infection |
hand sanitizer alone, hand washing alone, skin tape strip test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
National Jewish Health |
|
US |
2020-08-18 |
2021-08-20 |
3030005053, HS 0720, NCT04525521 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
40 |
Jessica Hui, Jessica Hui, MD |
2020-08-28 |
| COVIDSTORM: Use of Tocilizumab in the inflammatory phase of COVID-19 / new coronavirus disease |
Coronavirus disease 19 infection |
tocilizumab (intravenous), Roche/Chugai alone |
IL-6 receptor antagonist, IL-6 receptor modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Turku University Hospital |
|
Finland |
2020-06-17 |
|
2020-002039-31, COVIDSTORM, covidstorm |
Phase 3 Clinical |
Recruiting |
1 |
|
90 |
|
2020-08-28 |
| Rapid Screening Test for COVID-19 Antibodies in Healthcare Workers |
Coronavirus disease 19 infection |
AAZ rapid test alone, ELISA test alone, blood sampling alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Groupe d'Etude sur le Risque d'Exposition des Soignants aux Agents Infectieux |
|
France |
2020-04-25 |
2020-10-25 |
GERES20200409, ID RCB 2020-A01031-38, NCT04525417 |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
100 |
Charlotte Charpentier, MD, Elisabeth Bouvet, MD, Gerard Pellissier, PhD |
2020-08-28 |
| ThalaCoV: Frequency of COVID-19 Antibodies in Patients With Hereditary Hematological Diseases |
Coronavirus disease 19 infection, Diamond Blackfan anemia, Hematological disease, Sickle cell anemia, Thalassemia intermedia, Thalassemia major |
SARS-CoV-2 S1/S2 IgG analysis alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Milano-Bicocca |
|
Italy |
2020-07-14 |
2020-10-30 |
NCT04526405, THALACOV, ThalaCoV |
Phase Not Applicable |
Recruiting |
6 |
3 Months |
81 |
Alberto Piperno, Prof, Sara Pelucchi, Dr.ssa |
2020-08-29 |
| Morphological Abnormalities of the Olfactory Bulb on MRI and Olfactometry in Anosmic Versus Normosmic COVID-19 Patients |
Coronavirus disease 19 infection, Olfaction disorder |
anterior rhinoscopy alone, brain MRI alone, nasofibroscopy alone, olfactometry test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hopital Foch |
Raymond Poincare University Hospital |
France |
2020-09-06 |
2021-09-06 |
2020-0057, NCT04526054 |
Phase Not Applicable |
Not yet recruiting |
2 |
12 Months |
30 |
Elisabeth Hulier-Ammar, Dr, Jerome Lechien, Dr, Robert-Yves Carlier, Pr, Stephane Hans, Pr |
2020-08-28 |
| CHDR2029: In vitro characterization of the immune response of recovered COVID-19 patients and healthy controls to SARS-CoV-2 |
Coronavirus disease 19 infection |
blood sampling alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
ISA Pharmaceuticals BV |
|
|
2020-08-10 |
2020-09-30 |
CHDR2029, NL74814.058.20, NL8821 |
Phase Not Applicable |
Not yet recruiting |
0 |
1 Month |
14 |
I.M.C. de Visser-Kamerling |
2020-08-28 |
| ALCOVID: Assessment of Long-term Impact Post COVID-19 for Patients and Health Care Professionals of the European Hospital |
Coronavirus disease 19 infection |
serology test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hôpital Européen Marseille |
|
France |
2020-08-17 |
2022-10-31 |
2020- A01647-32, ALCOVID, NCT04525911 |
Phase Not Applicable |
Not yet recruiting |
1 |
26 Months |
258 |
Hervé PEGLIASCO, Myriam BENNANI |
2020-08-28 |
| Preparations of Dutch Emergency Departments for the SARS-COV-2 outbreak |
Coronavirus disease 19 infection |
|
|
|
Zuyderland Medical Center, Heerlen |
|
Netherlands |
2020-07-29 |
2020-10-01 |
NL8818, Z2020149 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
84 |
Rory O'Connor |
2020-08-28 |
| The Effect of COVID-19 on Patient Outcomes Among Operated Patients |
Coronavirus disease 19 infection |
surgery alone |
|
|
Karolinska Institutet |
|
Sweden |
2020-03-01 |
2020-12-31 |
COVIDKIRURGI, NCT04525716 |
Phase Not Applicable |
Recruiting |
1 |
10 Months |
2000 |
Andreas Älgå, Andreas Älgå, MD, PhD, Gabriel Sandblom, MD, PhD |
2020-08-31 |
| Endothelial Function and COVID-19 |
Coronavirus disease 19 infection |
EndoPat system, Itamar alone, Peripheral arterial tonometry alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Clinico San Carlos |
Mayo Clinic, Minnesota |
Spain, US |
2020-06-03 |
2020-09-30 |
20/451, NCT04525443 |
Phase Not Applicable |
Recruiting |
2 |
3 Months |
100 |
Alejandro Travieso, MD, Eduardo Martinez, MD, Hernan Mejia-Renteria, M.D, Hernan Mejia-Renteria, MD, Hernán Mejía-Rentería, MD, Javier Escaned, MD, PhD |
2020-08-29 |
| Lower morbidity and mortality in COVID-19 patients admitted in a dedicated COVID Hospital of Odisha - a radiological perspective |
Coronavirus disease 19 infection |
|
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kalinga Institute of Medical Sciences |
|
India |
2020-08-20 |
|
CTRI/2020/08/027247 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1500 |
Dr Roopak Dubey, Dr col Kamal Kumar sen |
2020-08-27 |
| VitCov: High Dose Vitamin-D Substitution in Patients With COVID-19: a Randomized, Controlled, Multicenter Study |
Coronavirus disease 19 infection, Vitamin D deficiency |
standard treatment alone, vitamin D3 alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kantonsspital Baselland |
|
Switzerland |
2020-09-01 |
2021-06-30 |
2020-01401, NCT04525820, VitCov |
Phase Not Applicable |
Not yet recruiting |
3 |
10 Months |
80 |
Fabienne Jaun, BScN, Jörg D Leuppi, Professor, Michael Brändle, Professor, Philipp Schütz, Professor, Prof. Dr. Jörg Leuppi |
2020-08-27 |
| Role of Tocilizumab in COVID-19 Pneumonia patients |
Coronavirus disease 19 infection, Viral pneumonia |
tocilizumab alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Gujarat Cancer Society Medical college hospital and research centre |
|
India |
2020-09-01 |
|
CTRI/2020/08/027246 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
40 |
Dr Jay Shah, Dr Shaila Shah |
2020-08-31 |
| MOIST: Multi-Organ Imaging With Serial Testing in COVID-19 Infected Patients |
Coronavirus disease 19 infection, Fatty liver disease, Heart injury, Inflammatory disease, Liver injury |
blood test alone, cognitive testing alone, high-sensitivity troponin testing alone, multi-organ MRI scan alone, olfaction testing alone, spiromety alone, walk test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Alberta |
Canadian VIGOUR Centre |
Canada |
2020-09-01 |
2021-09-01 |
MOIST, NCT04525404, PRO00102389 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
228 |
Ian Paterson, MD, Karin Kushniruk, RN, PhD |
2020-08-31 |
| Behavioral and emotional difficulties of school going children during COVID times |
Coronavirus disease 19 infection |
|
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) |
Lokopriya Gopinath Bordoloi Regional Institute of Mental Health |
|
India |
2020-08-29 |
|
CTRI/2020/08/027244 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
3500 |
Dr Subhashish Nath |
2020-08-26 |
| International phase II/III trial of GRAd-COV2 against covid-19 infection |
Coronavirus disease 19 infection |
GRAd-COV2 alone |
COVID19 Spike glycoprotein modulator |
|
ReiThera Srl |
|
|
|
|
|
Phase 2/Phase 3 Clinical |
Planned |
0 |
|
|
|
2020-08-26 |
| Identifying the factors that alters the recovery time of the COVID-19 patients |
Coronavirus disease 19 infection |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sri Ramachandra Hospital, Chennai |
|
India |
2020-09-11 |
|
CTRI/2020/08/027243 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
500 |
T Gayathri |
2020-08-27 |
| Study of Radiotherapy practice during Corona Pandemic |
Cancer, Coronavirus disease 19 infection |
radiotherapy alone |
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tata Memorial Hospital |
|
India |
2020-08-28 |
|
CTRI/2020/08/027226 |
Phase Not Applicable |
Recruiting |
1 |
|
2500 |
Jai Prakash Agarwal |
2020-08-27 |
| COVID-19 prevalence during pregnancy and pregnancy outcomes in low resource settings |
Coronavirus disease 19 infection |
blood sampling alone |
|
Female, Young Adults (18-44 yrs) |
Eunice Kennedy Shriver National Institute of Child Health & Human Development |
Global Network for Women's and Children's Health Research |
Pakistan, Congo, The Democratic Republic of the, Zambia, Kenya, India, Bangladesh |
2020-08-01 |
|
CTRI/2020/08/027218 |
Phase Not Applicable |
Not yet recruiting |
7 |
|
16000 |
Dr Archana Patel, Dr Shivaprasad S Goudar |
2020-08-28 |
| SCION: A backdated comparison of patients operated before the COVID-19 pandemic versus those operated during the COVID_19 pandemic |
Coronavirus disease 19 infection, Infectious disease |
cancer surgery alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tata Memorial Centre |
|
India |
2020-08-19 |
|
CTRI/2020/08/027210, SCION |
Phase Not Applicable |
Not yet recruiting |
1 |
|
3000 |
Dr Gouri Pantvaidya |
2020-08-27 |
| POMPCO: A survey to collect vital parameters and symptoms of participants at risk of COVID19 |
Coronavirus disease 19 infection |
wearable health device alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
INNOWEAR TECHNOLOGIES PRIVATE LIMITED |
|
India |
2020-08-26 |
|
CTRI/2020/08/027323, POMPCO |
Phase Not Applicable |
Not yet recruiting |
2 |
|
100 |
Dr Manoj Yadav, Megha Patel |
2020-08-27 |
| A study regarding knowledge, attitude and practice about immunity boosting measures for prevention of COVID-19 infection among healthcare workers at tertiary care hospital |
Coronavirus disease 19 infection |
Immunity Boosting measures for self-care alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Bhaikaka University |
|
India |
2020-09-15 |
|
CTRI/2020/08/027359 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
300 |
Dr Manisha Gohel |
2020-08-27 |
| To assess the clinical efficacy of Ayurvedic interventions in managing asymptomatic to mild cases of COVID-19 |
Coronavirus disease 19 infection |
Broncho-T Granules alone, Variable regimens including Agasthya Haritaki , Anu taila , Ayush-64 |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shri Dhanwantry Ayurvedic college and hospital |
|
India |
2020-08-25 |
|
CTRI/2020/08/027346 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
60 |
Shikha Chaudhary |
2020-08-28 |
| To Evaluate Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of DWRX-2003 Against COVID-19 |
Coronavirus disease 19 infection |
repositioned niclosamide (refractory lung disease/COVID-19), Daewoong Pharmaceutical/Institut Pasteur Korea alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Daewoong Pharmaceutical Co Ltd |
|
|
2020-08-31 |
2020-12-31 |
DWJ1516101_INDIA, NCT04524052 |
Phase 1 Clinical |
Not yet recruiting |
0 |
4 Months |
32 |
|
2020-08-27 |
| mCCP: Safety of convalescent plasma (CVP) drawn from mild symptomatic COVID-19 patients |
Coronavirus disease 19 infection |
|
|
Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
All India Institute of Medical Sciences |
|
China |
2020-08-21 |
|
CTRI/2020/08/027285, mCCP |
Phase Not Applicable |
Recruiting |
1 |
|
100 |
Diptiranjan Rout |
2020-08-28 |
| LLLT Treatment of Lung Inflammation in COVID-19 |
Coronavirus disease 19 infection, Lung inflammation, Respiratory distress syndrome, Viral pneumonia |
Non-invasive low-level laser therapy treatment alone, Standard care therapy alone, UltraSlim red/IR LED device alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ward Photonics LLC |
|
US |
2020-07-26 |
2021-01-31 |
CP19-02, NCT04524715 |
Phase Not Applicable |
Recruiting |
2 |
6 Months |
64 |
Gina M Brewer, Patty J Lee, MD, Randal Horsley, DC, Randal Horsley, DO, Rober H Burke, MD |
2020-08-28 |
| A study to evaluate the efficacy and safety of Aceinavir combined with supportive Standard of Care (SoC) in hospitalized patients with moderate coronavirus disease (COVID-19) |
Coronavirus disease 19 infection |
Aceinavir alone, Standard of Care (SoC) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Dyuthi Biosciences Private Limited |
|
India |
2020-08-28 |
|
CTRI/2020/08/027284, TG/PRO/CLI/035 Version 2.0 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
44 |
Dr Shashank Acharya, Dr Sruthi Nambiar, Dr Vishal Rao |
2020-08-28 |
| UNC CCP RCT: COVID-19 Antibody Plasma Research Study in Hospitalized Patients |
Coronavirus disease 19 infection, Gastrointestinal disease, Respiratory disease |
convalescent COVID-19 plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of North Carolina |
|
US |
2020-08-17 |
2021-05-31 |
20-1544, IGHID 12021, NCT04524507, UNC CCP RCT |
Phase 2 Clinical |
Recruiting |
1 |
9 Months |
56 |
Brian Gurney, ACNP, FNP, David M Margolis, MD, David van Duin, MD, PhD, JoAnn Kuruc, RN, MSN, Luther A Bartelt, MD |
2020-08-28 |
| A clinical trial to evaluate the medicinal efficacy and safety of ayurvedic kit in COVID-19 positive patients |
Coronavirus disease 19 infection |
Ayur Raksha capsules plus Ayur Raksha choorna |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
M/S AYURASHRAMA PHARMACEUTICALS |
|
India |
2020-08-24 |
|
CTRI/2020/08/027283 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
30 |
Dr BHAVYA DARSHINI M, Dr C R JAYANTHI, Dr VISHWA SANTHOSHA BHARATHI |
2020-08-28 |
| Clinical Trial of Ivermectin Plus Doxycycline for the Treatment of Confirmed COVID-19 Infection |
Coronavirus disease 19 infection |
antibiotic therapy alone, antihistamine therapy alone, drug therapy alone, oxygen therapy alone, vitamin intake alone, Variable regimens including doxycycline (Popular pharmaceutical limited) , ivermectin (Popular pharmaceutical limited) , low-molecular weight heparin , paracetamol |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Dhaka medical college |
|
Bangladesh |
2020-06-01 |
2020-08-30 |
ERC-DMC/ECC/2020/117, NCT04523831 |
Phase 3 Clinical |
Recruiting |
1 |
2 Months |
400 |
Mahmud Reaz, FCPS, Mahmud Reaz, FCPS, MD, Mahmud Reaz, FCPS. MD, Rahman Md Mujibur, FCPS |
2020-08-28 |
| Prophylactic Ivermectin in COVID-19 Contacts |
Coronavirus disease 19 infection |
ivermectin alone |
Chloride channel modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Government Institute of Medical Sciences, Greater Noida |
|
India |
2020-08-31 |
|
CTRI/2020/08/027282 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
180 |
Dr Hariom Kumar Solanki, Dr Rambha Pathak, Dr Saurabh Srivastava |
2020-08-26 |
| SPARTACOS-19 trial: Re-purposing of Anti HCV drugs for the treatment of COVID-19 disease |
Coronavirus disease 19 infection |
Daclatasvir/ Sofosbuvir alone, sofosbuvir + ledipasvir (fixed-combination/oral, HCV/HBV), Gilead alone |
Hepatitis C virus NS5B polymerase inhibitor, Hepatitis C virus protein NS5A inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Pt. B.D. Sharma PGIMS |
|
India |
2020-08-31 |
|
CTRI/2020/08/027345, SPARTACOS-19 trial |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
175 |
Dhruva Chaudhry |
2020-08-28 |
| Ivermectin as a possible treatment for COVID-19 |
Coronavirus disease 19 infection |
ivermectin alone |
Chloride channel modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
All India Institute of Medical Sciences Patna |
|
India |
2020-08-28 |
|
CTRI/2020/08/027225 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
90 |
Ravi Kirti |
2020-08-27 |
| Assessing the fear and worries associated with COVID-19 in out-patient population of a hospital |
Anxiety disorder, Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Gujarat Cancer Society Medical college hospital and research centre |
|
India |
2020-08-31 |
|
CTRI/2020/08/027281 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
250 |
Parth Shah |
2020-08-28 |
| To observe the effect of Ayurvedic medicine (Ashwagandha and Shunti) for the treatment of COVID-19 |
Coronavirus disease 19 infection |
Ashwagandha tablet plus Shunti |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Central Council for Research in Ayurvedic Sciences |
|
India |
2020-08-25 |
|
CTRI/2020/08/027224 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
60 |
Dr Harbans Singh, Dr Sumit Shrivastva |
2020-08-28 |
| The study of occurrence, distribution and control measures of COVID-19 among police personnel during pandemic in Pune city, Maharashtra |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
B.J.Medical College and Civil Hospital |
|
India |
2020-08-20 |
|
CTRI/2020/08/027275 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
200 |
Dr Ganesh Jagdale, Dr Malangori A Parande |
2020-08-28 |
| CARDY-COVID: Cardiac Dysfunction in Critically Ill Patients Infected With COVID-19 |
Coronavirus disease 19 infection, Heart disease |
Echocardiography alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sahlgrenska University Hospital |
|
Sweden |
2020-04-20 |
2020-09-30 |
CARDY-COVID, CARDY-COVID, NCT04524234 |
Phase Not Applicable |
Recruiting |
3 |
5 Months |
100 |
Jacob Holmqvist, MD, Jonatan Oras, MD, PhD |
2020-08-26 |
| Unani formulations for prevention of COVID-19 infection |
Coronavirus disease 19 infection |
Infuza alone, Kulzam alone, Infuza plus Kulzam |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Hamdard Laboratories |
|
India |
2020-08-24 |
|
CTRI/2020/08/027222 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
200 |
Dr Kailash Chandra, Dr Mridu Dudeja, Dr Naushad Rana, Mr Ayan Kumar Das |
2020-08-28 |
| A CBT-based Mobile Intervention as First Line Treatment for Adolescent Depression During COVID-19 |
Anxiety disorder, Coronavirus disease 19 infection, Depression |
Limbix Spark digital mobile application (Limbix Health, Inc) alone, cognitive behavioral therapy alone |
|
Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Limbix Health Inc |
|
US |
2020-07-20 |
2020-12-31 |
LIMBIX SPARK 02, NCT04524598 |
Phase Not Applicable |
Recruiting |
1 |
5 Months |
410 |
Aarthi Padmanabhan, PhD, Aarthi Padmanabhan, Phd, Jessica Lake, PhD, Marisa Cruz, MD |
2020-08-28 |
| Study to assess the usefulness, effectiveness and feasibility for future use of the consultations done using telephone/whatsapp in rheumatic diseases during CoVID-19 pandemic |
Coronavirus disease 19 infection, Musculoskeletal disease |
Tele-consultation alone |
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
All India Institute of Medical Sciences |
|
India |
2020-09-01 |
|
CTRI/2020/08/027324 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
5000 |
Ranjan Gupta |
2020-08-28 |
| Study of Descartes-30 in Acute Respiratory Distress Syndrome |
Coronavirus disease 19 infection, Respiratory distress syndrome |
Descartes-30 alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cartesian Therapeutics |
|
US |
2020-08-20 |
2022-09-25 |
DC30-1A, NCT04524962 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
2 |
25 Months |
30 |
Adam S Chowdhury, MD, MBA, Bruce D Levy, MD, Ryan Kennedy, MD |
2020-08-28 |
| Oral Camostat Compared With Standard Supportive Care in Mild COVID-19 Patients |
Coronavirus disease 19 infection |
Standard of care treatment alone, camostat mesylate alone |
Serine protease inhibitor, Transmembrane serine protease 2 inhibitor, Trypsin inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Stanford University |
|
US |
2020-08-31 |
2021-04-30 |
56029, COPS-2002, NCT04524663 |
Phase 2 Clinical |
Not yet recruiting |
1 |
8 Months |
120 |
Julie Parsonnet, MD |
2020-08-26 |
| Prevalence and Outcomes of Olfactory and Gustatory Dysfunctions in Patients With COVID-19 |
Coronavirus disease 19 infection, Dysgeusia, Dysomia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ain Shams University |
|
Egypt |
2020-07-11 |
2020-11-30 |
FMASUP46A/2020, NCT04524754 |
Phase Not Applicable |
Recruiting |
1 |
4 Months |
218 |
Fatma S Ebeid, MD, Mohamed Shehata Taha, ethical committee |
2020-08-29 |
| How does the COVID-19 quarantine affect physical activity levels? |
Coronavirus disease 19 infection |
physical activity alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Jobu hospital for respiratory diseases |
|
Japan |
2020-09-01 |
|
UMIN000041526 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
400 |
Keita Takagawa |
2020-08-27 |
| COVID19-OR (SARS-CoV-2): Observation, Risk And Recovery |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Western Sussex Hospitals NHS Trust |
|
UK |
2020-05-05 |
2022-05-08 |
20/YH/0157, COVID19-OR (SARS-CoV-2), NCT04524520 |
Phase Not Applicable |
Recruiting |
1 |
24 Months |
30 |
Dr Christina Koulouglioti, Dr Luke Hodgson, Dr Luke hodgson |
2020-08-27 |
| The effect of Atorvastatin therapy in COVID-19 |
Coronavirus disease 19 infection |
Variable regimens including atorvastatin , hydroxychloroquine , lopinavir + ritonavir |
HIV protease inhibitor, HMG CoA reductase inhibitor |
|
North Khorasan University of Medical Sciences |
|
Iran |
2020-08-20 |
|
IR.NKUMS.REC.1399.035, IRCT20190831044653N5 |
Phase 2 Clinical |
Recruiting |
1 |
|
160 |
Dr. Majid Ghafoori, Majid Ghafoori, Maryam Rameshrad, dr. seyed Kaveh Hojat |
2020-08-27 |
| Relation between HLA typing and ABO Blood group to infection by novel Wuhan Corona virus |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Christian Medical College, Vellore, India |
|
India |
2020-08-25 |
|
12752, CTRI/2020/08/027194 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
80 |
Snehil Kumar |
2020-08-27 |
| Impact of COVID -19 situation on people staying and discharged from a psychiatric rehabilitation centre |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kasturba Medical College, Manipal |
|
India |
2020-08-31 |
|
CTRI/2020/08/027193 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
54 |
Rajeshkrishna Bhandary P |
2020-08-27 |
| To assess the impact of COVID-19 pandemic on the delivery of radiation therapy in delhi national capital region, india |
Cancer, Coronavirus disease 19 infection |
|
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Max Super Speciality Hospital |
|
India |
2020-08-22 |
|
CTRI/2020/08/027192 |
Phase Not Applicable |
Not yet recruiting |
3 |
|
500 |
Dr Rashi Agrawal |
2020-08-27 |
| Effect of ifiltration of dexamethasone as primary emergency management in patients with symptomatic apical periodontitis during Coronavirus Disease 2019 outbreak |
Coronavirus disease 19 infection, Pain |
dexamethasone plus ligocaine |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Pacific Dental College and hospital |
|
India |
2020-08-24 |
|
CTRI/2020/08/027191 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
42 |
Dr Afzal Ali |
2020-08-27 |
| Response time of motorlance in COVID-19 pandemic |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Khon Kaen University |
|
Thailand |
2020-08-20 |
|
TCTR20200820006 |
Phase Not Applicable |
Recruiting |
1 |
|
871 |
Korakot Apiratwarakul |
2020-08-27 |
| Role of chest CT scan in covid19 patients: A study in a dedicated covid hospital of odisha |
Coronavirus disease 19 infection |
|
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
KIIT University |
|
India |
2020-08-20 |
|
CTRI/2020/08/027189 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1600 |
Sangram Panda |
2020-08-27 |
| The effect of Ayurvedic intervention (Ayurveda Raksha Kit) as a preventive measure in the Pandemic of COVID-19 - A community based study |
Coronavirus disease 19 infection |
Ayurvrda Raksha Kit alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Central Council for Research in Ayurvedic Sciences |
|
India |
2020-08-28 |
|
CTRI/2020/08/027316 |
Phase 3 Clinical |
Not yet recruiting |
20 |
|
|
Dr Alok Shrivastav, Dr Amin Hetalben, Dr Deepa Sharma, Dr Dipsunder Sahu, Dr EmySSurendram, Dr Gopesh Kumar, Dr Govind Reddy, Dr Jai Venkata Saiprasad, Dr K Anumol, Dr Kuldeep, Dr Laxman Bhurke, Dr PL Bharti, Dr Parvathy G Nair, Dr Rinky Thakur, Dr S Asha, Dr SK Vedi, Dr Seema jain, Dr Shriprakash, Dr Sunita mata, Dr Susmita P Otta, Dr Vineeta Kumari Negi |
2020-08-27 |
| Assessment of anxiety related to excessive internate search regarding covid-19 pandemic in medical students and para-medical staff |
Anxiety disorder, Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Gujarat Cancer Society Medical college hospital and research centre |
|
India |
2020-08-26 |
|
CTRI/2020/08/027301 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
200 |
Krishna Dave |
2020-08-27 |
| The effect of nebulizing peppermint extract and rose extract on percentage of blood oxygen saturation in patients with COVID-19 |
Coronavirus disease 19 infection |
peppermint extract (Barij Essence brand) alone, rose extract (Barij Essence brand) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Shahid Beheshti University of Medical Sciences |
|
Iran |
2020-06-29 |
|
IR.SBMU.RETECH.REC.1399.353, IRCT20190131042569N5 |
Phase 3 Clinical |
Recruiting |
1 |
|
60 |
Nima Saeedi, Seyed Ali Ziayi |
2020-08-27 |
| A Study to Evaluate the Safety and Immunogenicity of AdimrSC-2f Vaccine |
Coronavirus disease 19 infection |
AdimrSC-2f alone |
COVID19 Spike glycoprotein modulator |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Adimmune Corp |
|
Taiwan |
2020-08-20 |
2021-03-20 |
ADPCT20011X, NCT04522089 |
Phase 1 Clinical |
Recruiting |
1 |
7 Months |
70 |
Ellie Chen, Shan-Chwen Chang, Sung-Ching Pan, Szu-Min Hsieh, Wang-Da Liu |
2020-08-27 |
| TARGET-VIP: Prospective Hospital Registry of Patients With Suspected or Confirmed Coronavirus Infection (COVID-19) and Community-acquired Pneumonia |
Coronavirus disease 19 infection, Pneumonia, Viral pneumonia |
computerized tomography alone, polymerase chain reaction alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Research Center for Preventive Medicine |
Pirogov National Medical Surgical Center |
Russian Federation |
2020-04-06 |
2022-05-01 |
02-07/20, NCT04522076, TARGET-VIP |
Phase Not Applicable |
No longer recruiting |
2 |
24 Months |
1124 |
Andrey Pulin, MD, PhD, Mikhail Loukianov, MD, PhD, Sergey Martsevich, MD, PhD |
2020-08-28 |
| The effect of progressive muscle relaxation on covid-19 anxiety in pregnant women |
Anxiety disorder, Coronavirus disease 19 infection |
Progressive muscle relaxation technique training alone, Routine prenatal care alone |
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tehran University of Medical Sciences |
|
Iran |
2020-08-07 |
|
IR.TUMS.MEDICINE.REC.1399.287, IRCT20200630047962N1 |
Phase Not Applicable |
Recruiting |
1 |
|
126 |
Mohammadali Sahrayian, Mojgan Zendehdel |
2020-08-25 |
| TelePark: Efficacy and feasibility of Teleneurorehabilitation in Persons with Parkinsons Disease |
Coronavirus disease 19 infection, Parkinsons disease |
Tele-Neurorehabilitation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Lady Hardinge Medical College |
|
India |
2020-09-01 |
|
CTRI/2020/08/027300, TelePark |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Rajinder K Dhamija |
2020-08-27 |
| A study to find out possible causes of mortality amongst the Covid-19 patients that are admitted in GCS Medical College, Ahmedabad |
Coronavirus disease 19 infection |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Gujarat Cancer Society Medical college hospital and research centre |
|
India |
2020-08-31 |
|
CTRI/2020/08/027299 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
600 |
Dr Rushi Rashmikant Patel |
2020-08-25 |
| C3-RCT: Catalyzing the Containment of COVID-19 |
Coronavirus disease 19 infection, HIV infection |
nitazoxanide alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Cape Town |
Aurum Institute, National Institutes of Health, Perinatal HIV Research Unit, South African Medical Research Council, Texas Tech University, University Of Kwazulu-Natal |
South Africa |
2020-08-19 |
2021-08-31 |
C3-RCT, C3-RCT, NCT04523090 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
12 Months |
960 |
Ali Esmail, MD, Keertan Dheda, Keertan Dheda, MD/PhD |
2020-08-27 |
| Effect of oral health care and mouth rinse in treatment of Covid-19 |
Coronavirus disease 19 infection |
Professional oral health care education alone, Variable regimens including betadine , chlorhexidine , povidone-iodine |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kashan University of Medical Sciences and Health Services |
|
Iran |
2020-06-05 |
|
IR.KAUMS.REC.1399.015, IRCT20200527047581N1 |
Phase 2/Phase 3 Clinical |
No longer recruiting |
2 |
|
200 |
Dr. Hamidreza Banafsheh, Dr.Mohammad Reza Sharif, Elaheh GhasemzadehHosseini, Soltan Ali Bahmani |
2020-08-28 |
| Effectiveness of Siddha Medicines Kabasura Kudineer and Nilavembu Kudineer in the Management of Smptomatic COVID 19 patients |
Coronavirus disease 19 infection |
Kaba sura Kudineer alone, Nilavembu Kuidneer alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Central Council for Research in Siddha, Government Institute of Medical Sciences, Greater Noida |
|
India |
2020-08-22 |
|
CTRI/2020/08/027286 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
90 |
Dr ANURAG SRIVASTAVA, Dr R MANICKAVASAGM |
2020-08-26 |
| An Exploratory Study of ADR-001 in Patients With Severe Pneumonia Caused by SARS-CoV-2 Infection (COVID-19) |
Coronavirus disease 19 infection, Lung inflammation, Respiratory failure, Viral pneumonia |
ADR-001 alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Rohto Pharmaceutical Co Ltd |
|
Japan |
2020-09-30 |
2021-12-31 |
ADR-001-1919, NCT04522986 |
Phase 1 Clinical |
Not yet recruiting |
1 |
15 Months |
6 |
Rohto Pharmaceutical Co., Ltd., Yuji Fujino, MD |
2020-08-26 |
| CLBS-119 for Repair of COVID-19 Induced Pulmonary Damage |
Coronavirus disease 19 infection, Lung injury, Respiratory distress syndrome, Respiratory failure, Viral pneumonia |
CLBS-119 alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Caladrius Biosciences Inc |
|
US |
2020-09-30 |
2021-05-31 |
CLBS119-P01, NCT04522817 |
Phase 1 Clinical |
Not yet recruiting |
1 |
8 Months |
12 |
Christine L Kotynski, Douglas W Losordo, MD |
2020-08-27 |
| Ethnic Differences in the Impact of Breast Cancer on Employment Status, Financial Situation, and Quality of Life |
Breast tumor, Coronavirus disease 19 infection |
survey web-based or telephone interview alone |
|
Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Memorial Sloan-Kettering Cancer Center |
City University of New York, NYC Health & Hospitals/ Lincoln Medical Center, New York City Health and Hospitals Corp, New York Presbyterian Queens, Queens Medical Associates, Ralph Lauren Center for Cancer Care and Prevention |
US |
2010-05-31 |
2021-05-31 |
10-071, NCT01134172 |
Phase Not Applicable |
No longer recruiting |
15 |
132 Months |
935 |
Victoria Blinder, M.D., M.Sc. |
2020-08-27 |
| Metacognitive Therapy and Work Interventions for Patients on Sick Leave Due to Common Mental Disorders |
Anxiety disorder, Coronavirus disease 19 infection, Depression, Psychiatric disorder |
Metacognitive therapy alone, work-focused interventions alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Norwegian University of Science and Technology (NTNU) |
Diakonhjemmet Sykehus |
Norway |
2017-10-31 |
2023-04-30 |
2015/1794, NCT03301922 |
Phase Not Applicable |
Recruiting |
1 |
66 Months |
240 |
Odin Hjemdal, phd prof, Odin Hjemdal, prof, Ragne GH Gjengedal |
2020-08-28 |
| PCCE: Primary Care Clinical Excellence Incentive Study |
Coronavirus disease 19 infection |
Leadership Training alone, Monthly email communication alone, Social comparison Intervention alone, Standard communication email alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of California Los Angeles |
|
US |
2019-11-01 |
2021-07-01 |
12345, NCT04237883, PCCE |
Phase Not Applicable |
No longer recruiting |
1 |
20 Months |
225 |
Daniel M. Croymans |
2020-08-24 |
| A Transdiagnostic Course for Common Mental Health Problems in Primary Care |
Anxiety disorder, Coronavirus disease 19 infection, Depression |
Large-group transdiagnostic course alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Karolinska Institutet |
|
Sweden |
2020-08-31 |
2021-12-31 |
2019-04816, NCT04522713 |
Phase Not Applicable |
Not yet recruiting |
1 |
16 Months |
68 |
Erland Axelsson, PhD |
2020-08-24 |
| A trial to evaluate Zofin for the treatment of patients with Coronavirus disease 19 infection |
Coronavirus disease 19 infection |
Zofin alone |
|
|
Organicell Regenerative Medicine |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
1 |
|
2020-08-24 |
| TIP-OA: Telehealth Intervention Program for Older Adults |
Acute stress disorder, Coronavirus disease 19 infection, Psychiatric disorder |
Telehealth Intervention Program (TIP-OA) alone, semi-structured interviews alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Lady Davis Institute |
|
Canada |
2020-08-31 |
2022-08-31 |
NCT04523610, TIP-OA, TIP-OA |
Phase Not Applicable |
Not yet recruiting |
1 |
24 Months |
258 |
Harmehr Sekhon, PHD, Soham Rej, MD/MSc |
2020-08-27 |
| Impact of COVID-19 on Mental Health of Patients With Skin Picking |
Coronavirus disease 19 infection, Psychiatric disorder |
Internet-based Cognitive Behavioral Therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital de Clinicas de Porto Alegre |
Federal University of Rio Grande do Sul |
Brazil |
2020-08-11 |
2021-03-31 |
31520820.1.0000.5327, NCT04522492 |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
20 |
Carolina Blaya Dreher, PhD |
2020-08-27 |
| Does Quality of Life Decline During the COVID-19 Pandemic and Can we Change Behaviour to Improve Poor Quality of Life? |
Coronavirus disease 19 infection |
extended intervention alone, online questionnaire alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Manchester |
|
UK |
2020-05-22 |
2022-12-31 |
2020-9463-15184, NCT04522128 |
Phase Not Applicable |
Recruiting |
1 |
31 Months |
969 |
Christine Rowland, Tracy Epton |
2020-08-27 |
| NH-Shingrix: Training the Innate Immune System Against SARS-CoV-2 (COVID-19) Using the Shingrix Vaccine in Nursing Home Residents |
Coronavirus disease 19 infection, Influenza virus infection, Viral pneumonia |
GSK-1437173A alone |
|
Healthy volunteers accepted, Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Oklahoma |
Oklahoma Medical Research Foundation |
US |
2020-09-30 |
2021-09-30 |
NCT04523246, NH-Shingrix, OUHSC IRB12394 |
Phase 0 Clinical |
Not yet recruiting |
1 |
12 Months |
250 |
Barbara Carlson, Barbara W. Carlson, RN, Ph.D., Diana L Sturdevant, RN, Ph.D. |
2020-08-26 |
| Providing Suboxone and PrEP Using Telemedicine |
Coronavirus disease 19 infection, HIV infection, Opiate dependence |
Pre-exposure prophylaxis alone, Telemedicine alone, buprenorphine hydrochloride (oral, formulated with abuse-deterrent naloxone), Indivior alone |
Opioid receptor kappa antagonist, Opioid receptor mu agonist |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Duke University |
|
US |
2020-09-30 |
2021-05-31 |
NCT04521920, PRO00104147, PRO00104148 |
Phase 4 Clinical |
Not yet recruiting |
3 |
8 Months |
20 |
Hillary Chen, MPH, Hillary Murphy, MPH, Mehri McKellar, MD |
2020-08-25 |
| COCOVIH: COVID-19 and HIV Patients |
Coronavirus disease 19 infection, HIV infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre de Recherches et d'Etude sur la Pathologie Tropicale et le Sida |
|
France |
2020-07-01 |
2022-06-30 |
COCOVIH, CREPATS 013, NCT04523012 |
Phase Not Applicable |
Recruiting |
1 |
24 Months |
2200 |
Valerie POURCHER, MD, Valérie Pourcher, MD, Yasmine Dudoit, valérie Pourcher, MD |
2020-08-25 |
| CODYS: Measurement of the Efficacy of Morphine in the Early Management of Dyspnea in COVID-19 Positive Patients |
Coronavirus disease 19 infection, Dyspnea, Respiratory disease, Respiratory distress syndrome |
morphine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospices Civils De Lyon |
|
France |
2020-06-01 |
2021-02-28 |
CODYS, CODYS_2020, NCT04522037 |
Phase Not Applicable |
Recruiting |
3 |
9 Months |
200 |
Guillaume Economos, Dr, Myriam Legenne, Myriam Legenne, Dr, Sophie Francioni, Dr |
2020-08-27 |
| RECOVER: Rehabilitation After Admission in Intensive Care Unit for COVID-19 |
Coronavirus disease 19 infection |
|
|
|
Centre Hospitalier Régional Metz-Thionville |
|
France |
2020-04-01 |
2021-05-01 |
2020-05OBS-CHRMT, NCT04523051, RECOVER |
Phase Not Applicable |
Recruiting |
3 |
13 Months |
40 |
Armelle Stephan-Carlier, MD, Catherine Achour, MD, Clémence Deffinis, MD, Elise Schwartz-Leduc, MD, Margaux Temperelli, MD, Nadia Ouamara, Rémi Leclaire, MD, Vincent Dinot |
2020-08-26 |
| COVID19-CED-PÄD: Online survey on clinical care, health problems and str stress during the corona pandemic in children and adolescents with chronic inflammatory bowel disease (IBD) |
Acute stress disorder, Coronavirus disease 19 infection, Inflammatory bowel disease |
online questionnaire alone |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Technical University of Munich |
Klinikum Grosshadern Der Ludwig-Maximilians-Universitat |
Germany |
2020-08-25 |
|
20-690 KB and 20-642, COVID19-CED-PÄD, DRKS00022500 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
500 |
Elisabeth Klucker, Leandra Koletzko, Sibylle Koletzko, Thu Giang Le Thi, Tobias Schwerd |
2020-08-27 |
| Photobiomodulation anti-inflammatory effect in COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
Neolys (Life+) alone, photobiomodulation alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shaheed Beheshti Medical University |
|
Iran |
2020-06-30 |
|
IR.SBMU.NRITLD.REC.1399.131, IRCT20200616047799N1 |
Phase 1/Phase 2 Clinical |
No longer recruiting |
1 |
|
40 |
Alireza Eslaminejad, Mehran Marashian, Research department |
2020-08-25 |
| A randomized, double-blinded, placebo-controlled phase I/II clinical trial of Zofin against COVID-19 |
Coronavirus disease 19 infection |
Zofin alone |
|
|
Organicell Regenerative Medicine |
Alternative Research Associates, LLC, Larkin Community Hospital |
US |
|
|
|
Phase 1/Phase 2 Clinical |
Planned |
1 |
|
20 |
|
2020-08-24 |
| An observational study to assess the relation between previous treatment with ACE inhibitors, angiotensin-receptor blockers, beta-blockers, calcium-channel blockers, or thiazide diuretics and the likelihood of a positive or negative result on Covid-19 testing as well as the likelihood of severe illness (defined as intensive care, mechanical ventilation, or death) among patients who tested positive |
Coronavirus disease 19 infection |
ACE inhibitors (cardiovascular diseases), Jiangsu Kanion Pharmaceutical Co Ltd/China Pharmaceutical University alone, angiotensin receptor blockers (prodrug, cardiovascular diseases), KemPharm alone, beta blockers (glaucoma), University of Nottingham alone, calcium-channel blockers alone, thiazide diuretics alone |
ACE inhibitor, Angiotensin receptor antagonist, Beta 1 adrenoceptor antagonist |
|
National Center For Advancing Translational Sciences, National Institutes of Health, US Department of Health and Human Services |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
12594 |
|
2020-08-26 |
| Evaluation of the effect of SINA anti-flu natural product on COVID-19 |
Coronavirus disease 19 infection, Respiratory disease |
Variable regimens including SINA anti-flu medicinal natural product , azithromycin , naproxen |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Bagheiat-allah University of Medical Sciences |
|
Iran |
2020-09-22 |
|
IR.BMSU.REC.1399.038, IRCT20160131026298N5 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
80 |
AHMAD REZA SHARIFI OLOUNABADI, Ahmad Reza Sharifi Olounabadi, Gholamhosein Alishiri, mortezaazadi |
2020-08-25 |
| A clinical trial of ELI-004 for the prevention of Coronavirus disease 19 infection |
Coronavirus disease 19 infection |
ELI-004 alone |
TLR-9 agonist |
|
Elicio Therapeutics |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-08-24 |
| Evaluation of the effect of oral ivermectin on patients with COVID-19 |
Coronavirus disease 19 infection |
Variable regimens including azithromycin , hydroxychloroquine sulfate , ivermectin |
Chloride channel modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Tehran University of Medical Sciences |
|
Iran |
2020-04-19 |
|
IR.TUMS.MEDICINE.REC.1399.031, IRCT20180922041089N4 |
Phase 3 Clinical |
No longer recruiting |
3 |
|
130 |
Abolfazl Zendedel, Abolfazl Zendehdel, Mohammadali Sahraeeian, Saeedreza Jamali moghadam |
2020-08-26 |
| Phase III Trial of A COVID-19 Vaccine in Adults 18 Years of Age and Older |
Coronavirus disease 19 infection |
Ad5-nCoV alone |
COVID19 Spike glycoprotein modulator |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
CanSino Biologics Inc |
Institute of Biotechnology the Academy of Military Medical Sciences PLA |
Pakistan |
2020-08-30 |
2022-01-30 |
CS-CTP-AD5NCOV-III, NCT04526990 |
Phase 3 Clinical |
Not yet recruiting |
2 |
17 Months |
40000 |
Aamer Ikram SI, phD, Fengcai Zhu, Jinbo Gou, MD, Joanne M angley, MD, Scott A Halperin, MD |
2020-08-28 |
| BTL-TML-COVID: A Study in Adults to Test the Effects of Low Dose Thimerosal on Symptoms of COVID-19 |
Coronavirus disease 19 infection |
BTL-TML-COVID alone |
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Beech Tree Labs Inc |
Norwich Clinical Research Associates Ltd, The Curavita Corp |
US |
2020-07-30 |
2020-10-30 |
2020-04-0311, BTL-TML-COVID, NCT04522830 |
Phase 2 Clinical |
Recruiting |
1 |
3 Months |
40 |
DeAnn Sims, Duane Harris, MD, Lee Truax-Bellows, Tom Hatch |
2020-08-28 |
| A Phase II, Randomized, Double-blind, Placebo-controlled, Proof-of-Concept Study to Evaluate the Safety and Efficacy of Antroquinonol in Hospitalized Patients With Mild to Moderate Pneumonia Due to COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
antroquinonol alone |
MEK-1 protein kinase inhibitor, Ras gene inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Golden Biotechnology Corp |
|
|
2020-09-07 |
2021-03-31 |
GHCOVID-2-001, NCT04523181 |
Phase 2 Clinical |
Not yet recruiting |
0 |
6 Months |
174 |
|
2020-08-26 |
| A case-series of Herpes zoster infections in COVID‐19‐positive patients |
Coronavirus disease 19 infection, Varicella zoster virus infection |
hydroxychloroquine alone, mechanical ventilation alone, tocilizumab alone |
|
|
Universita di Bologna |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
4 |
|
2020-08-25 |
| A clinical study based on novel Coronavirus intelligent robot for nasopharyngeal swab sampling |
Coronavirus disease 19 infection |
nasopharyngeal swab sampling alone, novel Coronavirus intelligent robot alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shuguang Hospital Shanghai University Of Traditional Chinese Medicine |
|
China |
2020-10-01 |
2022-09-30 |
ChiCTR2000035985 |
Phase 0 Clinical |
Not yet recruiting |
1 |
24 Months |
|
Bin Shen |
2020-08-31 |
| PAMOCOS: Proadrenomedullin Assessment of Multi-Organ Failure in Covid-19 Sepsis |
Coronavirus disease 19 infection, Multiple organ failure, Sepsis, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier De Lens |
|
France |
2020-05-20 |
2020-10-07 |
2020-05, NCT04522310, PAMOCOS |
Phase Not Applicable |
Recruiting |
8 |
4 Months |
183 |
CLAIRE BOULLE, Dr, CLEMENT DELPIERRE, Dr, DELPHINE COLLING, Dr, FABIEN LAMBIOTTE, Dr, GUILLAUME BRUNIN, Dr, KATHY DERNIVOIX, MELANIE VERLAY, Mélanie VERLAY, Nicolas VAN GRUNDERBEECK, Dr, SEBASTIEN BEAGUE, Dr, THOMAS CAULIER, Dr |
2020-08-28 |
| Multi-center study on intelligent accurate diagnosis and critical illness prediction of novel coronavirus pneumonia (COVID-19) with multimodal imaging |
Coronavirus disease 19 infection, Pneumonia |
Etiological examination alone, multimodal imaging alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shanghai Public Health Clinical Center |
Shanghai shen-kang hospital clinical development center |
China |
2020-10-01 |
2023-11-01 |
ChiCTR2000036217 |
Phase 0 Clinical |
Not yet recruiting |
4 |
37 Months |
4000 |
Yuxin Shi |
2020-08-27 |
| Study of host genome variants in association to the varying severity of COVID-19 symptoms in Sabah patients |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universiti Malaysia Sabah |
|
Malaysia |
2020-09-01 |
2022-09-22 |
55933, NMRR-20-1785-55933 |
Phase Not Applicable |
Not yet recruiting |
1 |
24 Months |
|
Dr Lee Heng Gee, Professor Dr. Lee Ping Chin |
2020-08-27 |
| The Efficacy of Early Prone or Lateral Positioning in Severe COVID-19 Patients: a Single-Center, Prospective, Cohort Study |
Coronavirus disease 19 infection, Viral pneumonia |
Lateral Positioning alone, Prone Positioning alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
West China Hospital |
|
China |
2020-01-31 |
2020-02-15 |
ChiCTR2000035907 |
Phase 0 Clinical |
No longer recruiting |
1 |
|
197 |
Liu Dan, Ni Zhong |
2020-08-31 |
| Evaluation of the course of COVID-19 and perceptions among those tested positive – a survey based study |
Coronavirus disease 19 infection |
survey alone |
|
|
University of Heidelberg |
Gesundheitsamt Rhein-Neckar |
Germany |
2020-03-22 |
|
DRKS00022926, S-179/2020 |
Phase Not Applicable |
Suspended |
1 |
|
1000 |
Claudia Denkinger |
2020-08-27 |
| AVID-CC: Adalimumab for coronavirus in community care |
Coronavirus disease 19 infection, Respiratory failure |
Standard care alone, adalimumab biosimilar, Sandoz alone |
TNF alpha ligand inhibitor, TNF binding agent |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Oxford |
Wellcome Trust |
UK |
2020-07-01 |
2021-12-31 |
2020-003628-18, AVID-CC, IRAS 287434, ISRCTN33260034 |
Phase 2 Clinical |
Not yet recruiting |
2 |
18 Months |
750 |
Prof Richards |
2020-08-26 |
| A retrospective study to evaluate systematic assessment of venous thromboembolism (VTE) using complete duplex ultrasound (CDU) in anticoagulated COVID-19 patients |
Coronavirus disease 19 infection |
Complete duplex ultrasound alone, prophylactic anticoagulation therapy alone, therapeutic anticoagulation therapy alone |
|
|
Cochin Institute |
|
France |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
26 |
|
2020-08-24 |
| A prospective, observational study to characterize the coagulation profile of COVID-19 ARDS patients with standard and viscoelastic coagulation tests and to evaluate their changes after establishment of an aggressive thromboprophylaxis |
Coronavirus disease 19 infection, Respiratory distress syndrome |
clopidogrel alone, coagulation profiling alone, heparin alone, thromboprophylaxis alone |
P2Y12 purinoceptor antagonist |
|
IRCCS Policlinico San Donato |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
16 |
|
2020-08-24 |
| A case-series study to evaluate the efficacy of tissue plasminogen activator (tPA) treatment for COVID-19 associated acute respiratory distress syndrome (ARDS) |
Coronavirus disease 19 infection, Respiratory distress syndrome |
alteplase alone |
Tissue plasminogen activator stimulator |
|
Beth Israel Deaconess Medical Center, Harvard University, University of Colorado System |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
3 |
|
2020-08-24 |
| Epidemiological Analysis of Ambulant Patients in a COVID-19 Outpatient Clinic |
Coronavirus disease 19 infection |
|
|
|
Wissenschaftliches Institut Bethanien e.V. |
|
Germany |
2020-07-02 |
2020-12-31 |
NCT04521088, WI-1252 |
Phase Not Applicable |
Recruiting |
1 |
5 Months |
1000 |
Prof. Randerath, Prof. Dr, Simon Herkenrath |
2020-08-26 |
| AT-301 Nasal Spray in Healthy Adults |
Coronavirus disease 19 infection |
AT-301 (nasal spray, COVID-19), Atossa Therapeutics alone |
COVID19 Spike glycoprotein inhibitor |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Atossa Therapeutics Inc, Avance Clinical Pty Ltd |
|
Australia |
2020-08-07 |
2020-12-01 |
ACTRN12620000816954, AT-301-AU-01, NCT04519788 |
Phase 1 Clinical |
Recruiting |
2 |
3 Months |
50 |
Ben Canny, Dr Heather Fraser, Emir Redzepagic, MD, Jane Kelly, Meridee Arthur |
2020-08-31 |
| Impact of the COVID-19 pandemic and the political measures to contain its spread on children with disabilities and chronic illnesses and their families |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Universitätsklinik Freiburg Klinik für Allgemeine Kinder und Jugendmedizin Klinik für Neuropädiatrie und Muskelerkrankungen |
|
Germany |
2020-09-01 |
|
377/20, DRKS00022868 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
800 |
Thorsten Langer |
2020-08-25 |
| A phase I clinical trial of Ad26.COV2.S for potential treatment of COVID-19 infection |
Coronavirus disease 19 infection |
JNJ-78436735 alone |
|
|
Johnson & Johnson |
|
Brazil |
|
|
|
Phase 1 Clinical |
Planned |
1 |
|
6000 |
|
2020-08-21 |
| A clinical trial of urokinase plasminogen activator receptor targeted radio-immuno-therapeutics (uPRITs) for the potential treatment of patients with severe COVID-19 |
Coronavirus disease 19 infection |
urokinase plasminogen activator receptor targeted radio-immuno-therapeutics (uPRITs) alone |
|
|
Monopar Therapeutics LLC, Northstar Medical Radioisotopes Llc |
Aragen Bioscience Inc |
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-08-24 |
| CARR-COV-02: Efficacy of a Nasal Spray Containing Iota-Carrageenan in the Prophylaxis of COVID-19 Disease in Health Personnel Dedicated to Patients Care With COVID-19 Disease |
Coronavirus disease 19 infection |
Iota-Carrageenan alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centro de Educación Medica e Investigaciones Clínicas Norberto Quirno |
|
Argentina |
2020-07-24 |
2020-11-30 |
CARR-COV-02, CEMIC, NCT04521322 |
Phase 4 Clinical |
Recruiting |
1 |
4 Months |
400 |
Ariel Dogliotti, Juan Figueroa, MD, Mónica Lombardo, MD, Ricardo Valentini, MD, Ricardo c Valentini |
2020-08-25 |
| No-SARS: Antibodies Responses to COVID-19 Infection in Hospitalized Patients |
Coronavirus disease 19 infection |
ELISA alone, Luciferase assay alone, Luminometer alone, PV microneutralization assay alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Dammam |
Dammam Medical Complex, Institute for Research and medical consultation |
Saudi Arabia |
2020-08-31 |
2021-02-28 |
ICU-06072020, NCT04520880, No-SARS |
Phase Not Applicable |
Not yet recruiting |
1 |
6 Months |
158 |
Amani MM Alnimr, MD, Fatimah A Al-Mishkab, MD, Hisham A Almuzayyen, MD, Iman Almansour, Ph.D., Iman Almansour, PhD, Jawaher Almusairii, MD, Laila P Asonto, MD, Moaz S Alammar, MD, Mohamed R El Tahan, MD, Mohammed Alnabi, MD, Mohammed S Alshahrani, MD, Mohammed SS Alshahrani, MD, Talal A Albrahim, MD, Yousef Al Mubarak, MD |
2020-08-24 |
| Staff Absenteeism and Delivery of Healthcare Services During the COVID-19 Pandemic |
Coronavirus disease 19 infection |
|
|
|
Poznan University of Medical Sciences |
|
Poland |
2020-01-01 |
2020-04-30 |
3/2020/REH, NCT04521010 |
Phase Not Applicable |
Completed |
1 |
4 Months |
700 |
Ewa Chlebuś, MD |
2020-08-21 |
| MWLAHCW-COV: Mental workload assessment among healthcare worker among healthcare worker during pandemic COVID-19 at hospital Tunku Azizah (hospital kuala lumpur) |
Coronavirus disease 19 infection |
|
|
|
Hospital Tunku Azizah |
|
Malaysia |
2020-08-30 |
2020-12-31 |
54627, MWLAHCW-COV, NMRR-20-1769-54627 |
Phase Not Applicable |
Not yet recruiting |
1 |
4 Months |
|
Mr. MOHD ' AIZAT BIN MOHD BASARI |
2020-08-25 |
| The effect of herbal tea on improving respiratory symptoms in patients with Covid-19 |
Coronavirus disease 19 infection, Respiratory disorder |
herbal tea alone, routine treatment alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Isfahan University of medical Sciences |
|
Iran |
2020-09-22 |
|
IR.MUI.MED.REC.1399.359, IRCT20200806048318N1 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
80 |
Mehdi Akhve, Mehdi Akhveh, Shaghayegh Haghjoo Javanmard |
2020-08-26 |
| Characteristics in Post COVID-19 Patients |
Coronavirus disease 19 infection |
aerobic exercises alone, anaerobic exercises alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universidade Metodista de Piracicaba |
|
Brazil |
2020-08-11 |
2021-12-31 |
F110820, NCT04514705 |
Phase Not Applicable |
Recruiting |
1 |
16 Months |
20 |
Luiz F Falcão, PhD, Rodrigo S Rocha, Phd, Rodrigo Santiago Barbosa Rocha |
2020-08-24 |
| PRONE: Prone Position and Respiratory Outcomes in Non-Intubated COVID Patients |
Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia |
prone positioning alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Johns Hopkins University |
Duke University, Nox Medical, Smith & Nephew Inc, University of Miami, University of North Carolina, University of Pittsburgh |
|
2020-09-01 |
2021-12-31 |
IRB00249663, NCT04517123, PRONE |
Phase Not Applicable |
Not yet recruiting |
0 |
16 Months |
100 |
Mahendra Damarla, Naresh Punjabi, MD |
2020-08-24 |
| A clinical trial of autologous stromal vascular fraction for the treatment of severe respiratory distress due to COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
autologous stromal vascular fraction alone |
|
|
GID BIO |
Richard King Mellon Foundation |
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-08-21 |
| FERMIN: Fenofibrate as a Metabolic Intervention for COVID-19 |
Coronavirus disease 19 infection |
fenofibrate (micronized), Fournier/Abbott alone, usual care alone |
Lipoprotein lipase stimulator, PPAR alpha agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Pennsylvania |
University of Arizona |
US |
2020-08-18 |
2021-08-31 |
843729, FERMIN, NCT04517396 |
Phase 3 Clinical |
Recruiting |
1 |
12 Months |
300 |
Julio A. Chirinos |
2020-08-28 |
| The Investigation Into Beneficial Effects of High-dose Interferon Beta 1-a, Compared to Low-dose Interferon Beta 1-a in Moderate to Severe COVID-19 |
Coronavirus disease 19 infection |
interferon beta-1a follow-on biologic (subcutaneous), CinnaGen plus lopinavir + ritonavir |
HIV protease inhibitor, Interferon beta ligand |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shaheed Beheshti Medical University |
|
Iran |
2020-08-20 |
2020-09-11 |
INTERFERON IN COVID, NCT04521400 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
100 |
Behnam Rahimi, M.D, Firouze Hatami, M.D, Ilad Alavi Darazam, Ilad Alavi Darazam, M.D, Ilad Alavi Darazam, MD, Minoosh Shabani, M.D, Mohammad Mahdi Rabiei, M.D, Mohammad Reza Hajesmaeili, M.D, Omid Moradi, Seyed Sina Naghibi Irvani, M.D, Shervin Shokouhi, M.D |
2020-08-24 |
| Enhancement: Home-based Kidney Care in Native Americans of New Mexico (HBKC) |
Coronavirus disease 19 infection, Diabetes mellitus, End stage renal disease |
home-based kidney care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Native American Ancestry |
University of New Mexico |
Albuquerque area indian health board |
US |
2020-09-01 |
2021-09-30 |
16-344-ENHANCEMENT, Enhancement, NCT04520191 |
Phase Not Applicable |
Not yet recruiting |
1 |
13 Months |
529 |
Vallabh O Shah, Vallabh Shah, PhD |
2020-08-25 |
| A Phase III clinical trial of Cannabis sativa for the treatment of COVID-19 and other infectious diseases |
Coronavirus disease 19 infection |
Cannabis sativa alone |
|
|
Asia Green Biotechnology Corp, Pathway Rx Inc |
|
|
|
|
|
Phase 3 Clinical |
Planned |
0 |
|
15 |
|
2020-08-21 |
| A Phase II clinical trial of Cannabis sativa for the treatment of COVID-19 and other infectious diseases |
Coronavirus disease 19 infection |
Cannabis sativa alone |
|
|
Asia Green Biotechnology Corp, Pathway Rx Inc |
|
|
2021-01-31 |
|
|
Phase 2 Clinical |
Planned |
0 |
|
300 |
|
2020-08-21 |
| A clinical trial of replicating vesicular stomatitis virus vector-based vaccine (COVID-19), Israel Institute for Biological Research/Weizmann Institute of Science for the prevention of Covid-19 |
Coronavirus disease 19 infection |
VSV vector-based vaccine targeting spike glycoprotein (COVID-19), IIBR/Weizmann Institute of Science alone |
COVID19 Spike glycoprotein modulator |
|
Israel Institute for Biological Research |
Ministry of Health, Israel |
Israel |
2020-10-31 |
|
|
Phase Not Applicable |
Planned |
1 |
|
|
|
2020-08-26 |
| SARS-CoV-2 Antibodies Based IVIG Therapy for COVID-19 Patients |
Coronavirus disease 19 infection |
airway support therapy alone, anti-COVID-19 intravenous immunoglobulin alone, anti-pyretic therapy alone, anti-viral medication therapy alone, antibiotic treatment alone, fluid resuscitation alone, hemodynamic support treatment alone, painkiller treatment alone, steroid therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Dow University of Health Sciences |
Higher Education Commission of Pakistan |
Pakistan |
2020-06-19 |
2021-03-31 |
BIOTECH001, NCT04521309 |
Phase 1/Phase 2 Clinical |
Recruiting |
1 |
9 Months |
50 |
Dr. Mohsin Bajwa, FCPS, Dr. Muneeba Sayeed, FCPS, Dr. Shaukat Ali, PhD, Dr. Sheikh Muhammad Khan, MBBS, Dr. Shobha Luxmi, FCPS, Dr.Shaukat Ali, PhD, Mr. Abdul Samad Khan, M.Phil, Mr. Elisha Shalim, BS, Mr. Mir Rashid Ali, M.Sc, Mr. Mujtaba Khan, BS, Mr. Syed Muneeb Uddin, M.Sc, Ms. Ayesha Ali, M.Sc, Ms. Fatima Anjum, M.Sc, Prof. Dr. Mohammed Saeed Quraishy, FRCS, Prof. Dr. Mohammed Saeed Quraishy, FRCS, FCPS, Shaukat Ali, PhD, Shobha Luxmi, FCPS |
2020-08-24 |
| A clinical trial of COVID-19 vaccine (inactivated, Vero cells/intramuscular), Wuhan Institute of Biological Products/Wuhan Institute of Virology, CAS for the treatment of Covid-19 |
Coronavirus disease 19 infection |
COVID-19 vaccine (inactivated, Vero cells/intramuscular), Wuhan Institute of Biological Products/Wuhan Institute of Virology, CAS alone |
|
|
Sinopharm China National Biotech Institute Co Ltd, Thomson Reuters Corp |
|
Peru, Morocco |
|
|
|
Phase 3 Clinical |
Recruiting |
2 |
|
|
|
2020-08-21 |
| A placebo-controlled, randomized, double-blind, phase I clinical study to assess BT-20 in the treatment of patients with COVID-19 infection |
Coronavirus disease 19 infection, Respiratory distress syndrome |
BT-20, Bone Therapeutics alone, standard supportive treatment alone |
|
|
Bone Therapeutics SA |
|
Belgium |
|
|
|
Phase 1 Clinical |
Planned |
1 |
|
|
|
2020-08-26 |
| ReMiCov: Retinal Microangiopathy in Patients after Covid-19 Disease |
Coronavirus disease 19 infection, Microangiopathy |
optical coherence tomography angiography alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hannover Medical School |
|
Germany |
2020-07-13 |
|
9159_BO_K_2020, DRKS00022874, ReMiCov |
Phase Not Applicable |
Recruiting |
1 |
|
66 |
Jan Tode |
2020-08-25 |
| A phase I trial of COVID-19 vaccine(vaxipatch technology)for the potential treatment of COVID-19 |
Coronavirus disease 19 infection |
COVID-19 vaccine (vaxipatch technology, COVID-19 infection) Verndari/University of California Davis alone |
COVID19 Spike glycoprotein modulator |
|
Verndari Inc |
|
US |
|
|
|
Phase 1 Clinical |
Planned |
1 |
|
|
|
2020-08-28 |
| Efficacy and Safety of DWJ-1248 in Patients With Mild to Moderate COVID-19 Compared to the Placebo |
Coronavirus disease 19 infection |
DWJ-1248 alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Daewoong Pharmaceutical Co Ltd |
|
|
2020-08-31 |
2020-12-31 |
DW_DWJ1248201, NCT04521296 |
Phase 2 Clinical |
Not yet recruiting |
0 |
4 Months |
90 |
|
2020-08-24 |
| CPCP: Convalescent Plasma for COVID-19 Patients |
Coronavirus disease 19 infection |
convalescent plasma alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Vinmec Research Institute of Stem Cell and Gene Technology |
National Hospital Of Tropical Diseases, National Institute of Hematology and Blood Transfusion, Vietnam, National Institute of Hygiene and Epidemiology, Vietnam |
Vietnam |
2020-12-01 |
2021-10-30 |
CPCP, ISC.20.11.2, NCT04521036 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
10 Months |
44 |
Liem Thanh Nguyen, PhD, Phuong Hoang Nguyen, MPH |
2020-08-24 |
| A single-center, retrospective and observational study to assess famotidine in the treatment of patients with severe COVID-19 |
Coronavirus disease 19 infection |
famotidine alone |
Histamine H2 receptor antagonist |
|
Hartford Hospital |
|
US |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
83 |
|
2020-08-21 |
| iGenes-COVID19: Investigating the Involvement of ACE and Angiotensinogen Genes' Polymorphism Along With Other Thrombophilic Genotypes in Severe Forms of COVID-19 With/Without Thrombotic Events |
Arterial thrombosis, Coronavirus disease 19 infection, Cough, Deep vein thrombosis, Fever, Lung embolism, Myalgia, Myocardial infarction, Phlebothrombosis, Stroke |
multiplex PCR alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Grigore T. Popa University of Medicine and Pharmacy |
|
Romania |
2020-08-18 |
2021-08-18 |
GTP0051, NCT04519398, iGenes-COVID19 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
60 |
Adrian Covic, Professor, Alexandru Burlacu, Lecturer, Alexandru Burlacu, MD, PhD, Iolanda Popa, MD, PhD, Radu Crisan-Dabija, Lecturer, Radu Crisan-Dabija, MD, PhD |
2020-08-25 |
| The effect of selenium, vitamin C and methylprednisolone combination on mortality and morbidity of COVID-19 patients |
Coronavirus disease 19 infection, Respiratory distress syndrome |
Variable regimens including hydroxychloroquine , lopinavir + ritonavir , methylprednisolone , selenium , vitamin C |
HIV protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tabriz University of Medical Sciences |
|
Iran |
2020-06-29 |
|
IR.TBZMED.REC.1399.340, IRCT20190312043030N2 |
Phase 3 Clinical |
Recruiting |
1 |
|
40 |
Dr Abolghasem Joyban, Dr.Seied Hadi Saghaleini |
2020-08-25 |
| SPP – SmartPointer Pilot study: Pilot study to investigate the SmartPointer system in the context of domestic life with older people in need of support |
Aging, Coronavirus disease 19 infection |
SmartPointer (SP) system alone |
|
Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Charite Universitaetsmedizin Berlin |
Bundesministerium fur Bildung und Forschung |
Germany |
2020-12-01 |
|
DRKS00022533, EA1/137/20, SPP – SmartPointer Pilot study, U1111-1256-0263 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
117 |
Susan Vorwerg |
2020-08-21 |
| Transpulmonary Pressure Measurements in Intubated Children With Covid-19 Respiratory Failure |
Coronavirus disease 19 infection, Respiratory failure |
transpulmonary pressure measurement alone |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) |
Mayo Clinic, Minnesota |
|
US |
2020-05-21 |
2021-01-31 |
20-003743, NCT04519411 |
Phase Not Applicable |
Recruiting |
1 |
8 Months |
10 |
Stephen Gleich, M.D., Stephen J Gleich, MD |
2020-08-25 |
| MFMU COVID-19: Maternal Morbidity and Mortality During the COVID-19 Pandemic |
Coronavirus disease 19 infection, Pregnancy disorder |
|
|
Female |
The George Washington University Biostatistics Center |
Eunice Kennedy Shriver National Institute of Child Health & Human Development |
US |
2020-06-23 |
2021-12-31 |
HD36801 - MFMU COVID-19, MFMU COVID-19, NCT04519502, U01HD036801 |
Phase Not Applicable |
Recruiting |
12 |
18 Months |
26400 |
Alan T. Tita, MD, Amber Sowles, RN BSN CORP, Andrew Bremer, MD, PhD, MAS, Anna Bartholomew, RN,BSN,CCRP, Ashley Salazar, MSN, Cora MacPherson, PhD, Cynthia Gyamfi-Bannerman, MD, Donna Allard, RN, Dwight J Rouse, MD, Felecia Ortiz, RN,BSN,CCRC, Gail Mallett, RN,BSN, CCRC, George R Saade, MD, Hyagriv Simhan, MD, MS, Janatha Grant, BSN, Jennifer Bailit, MD, Jennifer Craig, BSN, John M. Thorp Jr., MD, Kelly Clark, RN BSN, Maged Costantine, MD, Melissa Bickus, BS, RN, Rebecca Clifton, PhD, Sabine Bousleiman, RNC MSN, Samuel Parry, MD, Suneet Chauhan, MD, Torri Metz, MD, Wendy Dalton, RNC, William Grobman, MD |
2020-08-24 |
| Covid-Screen Quality Control: SARS-CoV-2 /COVID-19 Admission Screening in a University Hospital Setting |
Coronavirus disease 19 infection |
nasopharyngeal sampling alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Basel |
|
Switzerland |
2020-04-01 |
2021-03-31 |
2020-00808, Covid-Screen Quality Control, NCT04519372 |
Phase Not Applicable |
No longer recruiting |
1 |
12 Months |
4099 |
Sarah Tschudin-Sutter, Prof. Dr. MD |
2020-08-31 |
| DALIA: Evaluation of the effect and the safety of the CIGB-258 peptide in the treatment of severe or critical patients due to COVID-19 |
Coronavirus disease 19 infection |
CIGB-258 alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Center for Genetic Engineering and Biotechnology, Consejo Nacional de Ciencia y Tecnología, Mexican Health Research Coordination |
|
Mexico |
2020-08-11 |
|
DALIA, IG/CIGB-258I/CV/2001, RPCEC00000330 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
60 |
Francisco Hernandez Bernal, Juan Anda Garay |
2020-08-31 |
| A clinical trial of AV-001 for the treatment of COVID-19-associated acute lung injury and acute respiratory distress syndrome (ARDS) |
Acute lung injury, Coronavirus disease 19 infection, Respiratory distress syndrome |
AV-001, Vasomume Therapeutics alone |
Tek tyrosine kinase receptor stimulator |
|
Vasomune Therapeutics Inc |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-08-26 |
| Determination of the Hemoadsorption Impact as Adjunctive Treatment Upon the Support Therapy of COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
CytoSorb alone, continuous renal replacement therapy alone, fluid challenge alone, inotropic support alone, mechanical ventilation alone, vasopressor therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Brugmann University Hospital |
|
Belgium |
2020-05-03 |
2020-12-01 |
BRUGMANNUH 1066, NCT04518969 |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
24 |
Dr David DE BELS, Patrick Honore, MD, Patrick Honoré, MD |
2020-08-20 |
| A clinical trial of AK-119 for the treatment of COVID-19 patients |
Coronavirus disease 19 infection |
AK-119 alone |
CD73 antagonist |
|
Akeso Biopharma Inc |
|
New Zealand |
|
|
|
Phase Not Applicable |
Planned |
1 |
|
|
|
2020-08-20 |
| External pilot study to evaluate the feasibility of the development of a pragmatic clinical trial to determine the clinical utility of the repositioning of Pentoxifylline as an immunomodulator and regulator of the Renin Angiotensin system in the treatment of COVID-19 |
Coronavirus disease 19 infection |
pentoxifylline alone |
Phosphoric diester hydrolase inhibitor |
|
IMSS General Hospital of Zone 2A "Troncoso" |
|
Mexico |
|
|
2020-785-079 |
Phase 4 Clinical |
Status not specified |
1 |
|
50 |
|
2020-08-24 |
| Epidemiological survey of COVID-19 patients in Japan |
Coronavirus disease 19 infection |
|
|
|
Hiroshima University |
|
Japan |
2020-05-12 |
|
UMIN000041450 |
Phase Not Applicable |
Recruiting |
1 |
|
10000 |
Nobuaki Shime, Shinichiro Ohshimo |
2020-08-24 |
| COVID-19 in Lahad Datu |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
HOSPITAL LAHAD DATU |
|
Malaysia |
2020-08-16 |
2020-12-15 |
55950, NMRR-20-1756-55950 |
Phase Not Applicable |
Status not specified |
1 |
4 Months |
54 |
Dr CHEO SENG WEE |
2020-08-31 |
| MKK-COVID-19: Health Awareness Model and COVID-19 Outbreak Containment Behavior Among Sri Petaling Mosque Clusters |
Coronavirus disease 19 infection |
|
|
|
Institute for Health Behavioural Research (IHBR) |
|
Malaysia |
2020-08-31 |
2021-01-31 |
55269, MKK-COVID-19, NMRR-20-1760-55269 |
Phase Not Applicable |
Status not specified |
2 |
5 Months |
|
Mr Abu Bakar Bin Rahman |
2020-08-21 |
| Vitamin D Status and Immune-inflammatory Status in Different UK Populations With COVID-19 Infection |
Coronavirus disease 19 infection |
|
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Guy's & St Thomas' Hospital NHS Trust |
|
UK |
2020-09-01 |
2020-12-31 |
285176, NCT04519034 |
Phase Not Applicable |
Not yet recruiting |
1 |
4 Months |
27000 |
Agata Sobczynska-Malefora, PhD, Rachel Fay, Ms |
2020-08-21 |
| A study to assess risk of mortality and current health characteristics of Covid-19 patients |
Coronavirus disease 19 infection |
|
|
|
LifeBridge Health, PeraHealth, Sinai Hospital of Baltimore, Yale New Haven Health |
|
US |
|
|
|
Phase Not Applicable |
Status not specified |
2 |
|
|
|
2020-08-20 |
| TRACE: Transmission of Covid-19 in Crowded Environments |
Coronavirus disease 19 infection |
STOPCOV alone |
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Desmond Tutu HIV Foundation |
European and Developing Countries Clinical Trials Partnership, University of Cape Town |
South Africa |
2020-08-03 |
|
PACTR202008485004797, TRACE |
Phase Not Applicable |
Not yet recruiting |
7 |
|
720 |
Catherine Orrell, Lara Fairall, LindaGail Bekker, Philip Smith |
2020-08-31 |
| COV-RECUP: Medium and Long Term Follow-up of COVID-19 Infected Patients: Research and Characterization of Pulmonary Sequelae |
Coronavirus disease 19 infection, Viral pneumonia |
CT Scan alone, Pulmonary function testing alone, Ventilatory polygraphy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
University Hospital of Besancon |
|
France |
2020-05-18 |
2025-08-18 |
2020/499, COV-RECUP, NCT04519320 |
Phase Not Applicable |
Recruiting |
1 |
63 Months |
140 |
Eberst Guillaume, PH, Guillaume Eberst, PH, Lucie Laurent, PhD |
2020-08-25 |
| A follow-up study to evaluate Lucid Robotic System to generate additional findings on the pathophysiology of COVID-19 |
Coronavirus disease 19 infection |
Lucid Robotic System alone |
|
|
NovaSignal Corp |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
|
|
2020-08-20 |
| A study to evaluate Lucid robotic system to remotely assess and monitor critically ill patients with COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
Lucid robotic system alone |
|
|
NovaSignal Corp |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
18 |
|
2020-08-20 |
| Evaluation of Newborns Presenting With Suspected COVID-19 |
Coronavirus disease 19 infection, Respiratory disease |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Dr. Behcet Uz Children's Hospital |
|
Turkey |
2020-03-01 |
2020-08-31 |
2020/251, NCT04519307 |
Phase Not Applicable |
No longer recruiting |
1 |
6 Months |
72 |
Senem Alkan Özdemir |
2020-08-23 |
| Daily Regimen of Tenofovir/Emtricitabine as Prevention for COVID-19 in Health Care Personnel in Colombia |
Coronavirus disease 19 infection |
personal protective equipment (PPE) alone, tenofovir disoproxil fumarate + emtricitabine (fixed dose), Gilead Sciences alone |
HIV-1 reverse transcriptase inhibitor, Nucleoside reverse transcriptase inhibitor |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Hospital Universitario San Ignacio |
Colombia National University Hospital, Fundación Universitaria Autónoma de Las Américas, Hospital Universitario San Jorge de Pereira, Hospital de la Samaritana, Sede Bogotá y Sede Zipaquirá, Javeriana University, Universidad Tecnológica de Pereira |
Colombia |
2020-08-30 |
2021-04-01 |
2020 /143, 77389, NCT04519125 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
7 Months |
950 |
Juliana Maria Cuervo Rojas, MD. MSc. PhD., Sandra Liliana Valderrama, MD, Sandra Valderrama- Beltrán, MD. Msc. |
2020-08-23 |
| Adapt Out COVID: A Study for Outpatients With COVID-19 |
Coronavirus disease 19 infection |
LY-CoV555 alone |
COVID19 Spike glycoprotein modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Institute of Allergy and Infectious Diseases |
AIDS Clinical Trials Group, Eli Lilly & Co |
US |
2020-08-19 |
2021-02-28 |
38742, A5401/ACTIV-2, Adapt Out COVID, NCT04518410 |
Phase 2/Phase 3 Clinical |
Recruiting |
5 |
6 Months |
2000 |
Becky Straub, Chris Jonsson, David Smith, MD, MAS, Jay Dwyer, Lisa Kessels, Samantha Fortier |
2020-08-27 |
| Telemedical Risk Assessment and Preoperative Evaluation (TAPE) |
Anesthesia, Coronavirus disease 19 infection |
TAPE Software alone, Telemedicine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Docs in Clouds Telecare GmbH, Rheinisch-Westfaelische Technische Hochschule Aachen |
|
Germany |
2020-04-20 |
2020-11-30 |
19-174, NCT04518514 |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
100 |
Andreas Follmann, Dr., Jan Wienhold, cand. med. |
2020-08-22 |
| FLOWER: Fixed Low-dose Eltrombopag and rhTPO for Immune Thrombocytopenia |
Coronavirus disease 19 infection, Immune thrombocytopenic purpura |
eltrombopag plus recombinant human thrombopoietin (sc, idiopathic thrombocytopenic purpura/thrombocytopenia/aplastic anemia), 3SBio |
Thrombopoietin receptor agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
People's Hospital Peking University |
|
China |
2020-08-31 |
2022-06-30 |
FLOWER, ITP-PKU019, NCT04518878 |
Phase 1 Clinical |
Not yet recruiting |
1 |
22 Months |
30 |
Xiaohui Zhang, MD, Xuelin Dou, MD |
2020-08-27 |
| Toclizumam Versus Dexamethasone in Severe Covid19 Cases |
Coronavirus disease 19 infection |
Variable regimens including azithromycin , hydroxychloroquine , methylprednisolone (Pfizer) , tocilizumab |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
South Valley University |
|
Egypt |
2020-03-01 |
2020-08-05 |
NCT04519385, SOUTHVU |
Phase 2 Clinical |
Completed |
1 |
5 Months |
69 |
Alaa R rashad, MD |
2020-08-21 |
| Study for Quantitative Analysis of the Recovered COVID-19 Patients by [18]F-FDG-PET/CT |
Coronavirus disease 19 infection |
[18]F-FDG alone, computed tomography alone, positron emission tomography alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fifth Affiliated Hospital, Sun Yat-Sen University |
|
China |
2020-07-01 |
2023-07-31 |
NCT04519255, ZDWY.FZYX.008 |
Phase Not Applicable |
No longer recruiting |
1 |
37 Months |
60 |
Hong Shan, Ph.D |
2020-08-21 |
| CSL-324 in COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
Standard of care alone, CSL-324 plus remdesivir |
COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, GCSF receptor antagonist, RNA polymerase modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
CSL Behring, CSL Ltd |
|
|
2020-08-31 |
2021-05-31 |
CSL324_COVID-19, NCT04519424 |
Phase 2 Clinical |
Not yet recruiting |
0 |
9 Months |
124 |
|
2020-08-21 |
| A clinical study to assess XoGlo in the treatment of COVID-19 related inflammatory disease |
Coronavirus disease 19 infection, Inflammatory disease, Respiratory distress syndrome |
XoGlo alone |
|
|
Kimera Labs |
|
US |
|
|
|
Phase Not Applicable |
Planned |
1 |
|
160 |
|
2020-08-20 |
| A human-challenge trial to evaluate CodaVax-COVID in healthy subjects |
Coronavirus disease 19 infection |
CodaVax-COVID alone |
|
Healthy volunteers accepted |
Codagenix Inc |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-08-20 |
| CORONA: Evolution of COVID-19 in Anticoagulated or Antiaggregated Patients |
Coronavirus disease 19 infection |
acenocoumarol alone, apixaban alone, aspirin alone, cangrelor alone, clopidogrel alone, dabigatran etexilate mesylate alone, dipyridamol alone, edoxaban alone, prasugrel alone, rivaroxaban alone, ticagrelor alone, vitamin K antagonist therapy alone, warfarin alone |
Factor IIa antagonist, Factor IX antagonist, Factor VII antagonist, Factor X antagonist, Factor Xa antagonist, P2Y12 purinoceptor antagonist, Protease-activated receptor-1 antagonist, Vitamin K epoxide reductase inhibitor |
|
Fundacio Institut De Recerca De L'Hospital De La Santa Creu I Sant Pau |
|
Spain |
2020-04-01 |
2020-06-30 |
CORONA, IIBSP-COV-2020-24, NCT04518735 |
Phase Not Applicable |
Completed |
1 |
3 Months |
1707 |
|
2020-08-21 |
| On-Line Collectives in Mental Health: Transdisciplinary Action for Groups Vulnerable to COVID-19 |
Coronavirus disease 19 infection |
online intervention sessions alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul |
Universidado de Passo Fundo |
Brazil |
2020-07-15 |
|
31919020.6.1001.5342, 4.164.222, RBR-4vy54v, U1111-1253-9181 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
500 |
Ana Luisa Sant'Anna Alves, Silvana Alba Scortegagna |
2020-08-21 |
| Study Assessing the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Repeated Subcutaneous Doses of Anti-Spike (S) SARS-CoV-2 Monoclonal Antibodies (REGN-10933 + REGN-10987) in Adult Volunteers as Related to COVID-19 |
Coronavirus disease 19 infection |
REGN-CoV2 alone |
COVID19 Spike glycoprotein inhibitor |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Regeneron Pharmaceuticals Inc |
|
US |
2020-07-26 |
2021-07-06 |
NCT04519437, R10933-10987-HV-2093 |
Phase 1 Clinical |
Recruiting |
4 |
11 Months |
420 |
Clinical Trial Management, Clinical Trials Administrator |
2020-08-21 |
| COVIDDEPERINAT: Effect of Tele-consultation in Addition With Psychiatric Follow-up During COVID-19 in Women Who Have Medical History of Post-partum Depression |
Anxiety disorder, Coronavirus disease 19 infection, Postnatal depression |
tele-consultation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assistance Publique Hopitaux de Paris |
|
France |
2020-09-30 |
2020-09-30 |
APHP200878, COVIDDEPERINAT, NCT04516668 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
250 |
Emmanuelle Corruble, Pr, Florence Gressier, Dr |
2020-08-21 |
| Renal Biomarkers in AKI and COVID-19 |
Coronavirus disease 19 infection, Renal injury, Viral pneumonia |
metabolomic test alone, tocilizumab alone, urinary IGFBP7 test alone, urinary IL-6 test alone, urinary NGAL test alone, urinary TIMP-2 test alone, viral load test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Instituto Nacional de Enfermedades Respiratorias |
|
Mexico |
2020-06-01 |
2020-09-30 |
C26-20, NCT04517630 |
Phase Not Applicable |
Recruiting |
1 |
4 Months |
90 |
Amy B. Peralta Prado, MD, Santiago Avila Rios, PhD, Santiago Avila Ríos, PhD, Santiago Ávila Ríos, PhD |
2020-08-22 |
| COMETS: Coronavirus Studied by Metagenomics in ARDS COVID-19 Patients |
Coronavirus disease 19 infection, Respiratory distress syndrome |
MetaMIC software alone, Nextera XT kit alone, NovaSeq (Illumina) alone, QiaSymphony alone, Stranded TruSeq Total RNA (Illumina) alone, biological sampling alone, metagenomic and transcriptomic analysis alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assistance Publique Hopitaux de Paris |
|
France |
2020-03-09 |
2020-12-31 |
APHP200418, COMETS, NCT04516486 |
Phase Not Applicable |
No longer recruiting |
1 |
9 Months |
180 |
Christophe Rodriguez, PharmD, PhD |
2020-08-21 |
| COVID-19 and SARS-CoV-2 Detection in Saliva |
Coronavirus disease 19 infection |
TaqPath RT-PCR alone, biological sampling alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ambry Genetics Corp |
Crozer-Keystone Health System, St. Joseph Hospital of Orange, The Saratoga Hospital |
US |
2020-05-21 |
2020-12-30 |
COV_20_001, NCT04517682 |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
300 |
Brigette Tippin Davis, PhD |
2020-08-26 |
| CONVINCE: Corona Virus Edoxaban Colchicine (CONVINCE) COVID-19 |
Coronavirus disease 19 infection, Thrombosis |
colchicine alone, edoxaban alone, colchicine plus edoxaban |
Factor Xa antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Inselspital, Berne |
Daiichi Sankyo Co Ltd, Daiichi Sankyo Europe GmbH |
Switzerland |
2020-10-01 |
2021-12-31 |
CONVINCE, CONVINCE VERSION 1.0 12052020, NCT04516941 |
Phase 3 Clinical |
Not yet recruiting |
2 |
15 Months |
420 |
Olga Deckarm, MD, Stephan Windecker, Stephan Windecker, MD, Stephan Windecker, Prof. Dr. |
2020-08-21 |
| CPCP: Convalescent Plasma for COVID-19 Patients |
Coronavirus disease 19 infection |
convalescent COVID-19 plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Vinmec Research Institute of Stem Cell and Gene Technology |
National Institute for Infectious And Tropical Diseases, National Institute of Hematology and Blood Transfusion, Vietnam, National Institute of Hygiene and Epidemiology, Vietnam |
Vietnam |
2020-08-01 |
2020-12-30 |
CPCP, ISC.20.11, ISC.20.11.1, NCT04516954 |
Phase 0 Clinical |
Recruiting |
1 |
4 Months |
10 |
|
2020-08-21 |
| Hyperbaric oxygen therapy for hospitalized patients with COVID-19 |
Coronavirus disease 19 infection |
hyperbaric oxygen therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Federal University of Juiz de Fora (UFJF), Universidade Federal de Minas Gerais |
Hospital e Maternidade Therezinha de Jesus |
Brazil |
2020-08-18 |
|
31831420.9.1001.5149, 4.137.642, RBR-2fvjjm, U1111-1253-2793 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
40 |
Daniel Baumfeld, José da Mota Neto, Rafael Zambelli Pinto |
2020-08-21 |
| APC Trial: Randomized, study to evaluate early prone position in patients with COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
prone position alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Brasília |
|
Brazil |
2020-08-30 |
|
33576620.9.1001.5455, 4.151.555, APC Trial, RBR-2k66ft, U1111-1253-7949 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
200 |
Rodrigo Santos Biondi |
2020-08-31 |
| HSD3B1 Gene Polymorphisms With Outcomes in SARS-CoV-2 Infected Patients |
Coronavirus disease 19 infection |
RNA sampling alone, Sanger sequencing alone, formalin-fixed paraffin embedded tissue blocks alone, polymerase chain reaction alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Oncology Institute of Southern Switzerland |
Institute of Oncology Research (Switzerland), Istituto Cantonale di Patologia |
Switzerland |
2020-09-01 |
2021-08-31 |
COVID19-GENEEXP, NCT04516850 |
Phase Not Applicable |
Not yet recruiting |
2 |
12 Months |
500 |
Christian Garzoni, MD, Ricardo Pereira Mestre, Ricardo Pereira Mestre, MD |
2020-08-28 |
| ELABORATE-19: Eltrombopag Plus rhTPO Versus Eltrombopag for ITP During the COVID-19 Pandemic |
Coronavirus disease 19 infection, Immune thrombocytopenic purpura |
eltrombopag plus recombinant human thrombopoietin (sc, idiopathic thrombocytopenic purpura/thrombocytopenia/aplastic anemia), 3SBio |
Thrombopoietin receptor agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
People's Hospital Peking University |
|
China |
2020-08-31 |
2022-08-31 |
ELABORATE-19, ITP-PKU020, NCT04516837 |
Phase 2 Clinical |
Not yet recruiting |
1 |
24 Months |
120 |
Xiaohui Zhang, MD, Xuelin Dou, MD |
2020-08-21 |
| Therapeutic Use of Convalescent Plasma in the Treatment of Patients With Moderate to Severe COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
COVID-19 convalescent plasma alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
South African National Blood Service |
|
South Africa |
2020-09-03 |
2022-07-31 |
NCT04516811, PROTECT-PATIENT TRIAL |
Phase 3 Clinical |
Not yet recruiting |
1 |
22 Months |
600 |
Cynthia Nyoni, Karin vandenBerg, Dr, Mpumi Maxebengula, BCom, Sean Wasserman, A/Professor |
2020-08-21 |
| BVAC19: Blood Volume Assessment in COVID-19 ICU Patients |
Coronavirus disease 19 infection |
BVA-100 software package alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
NYU Langone Health |
|
US |
2020-08-01 |
2021-02-01 |
20-00896, BVAC19, NCT04517695 |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
30 |
Jan Bakker, MD, PhD |
2020-08-20 |
| COVID-TRUST: Impact of Perceived Control on Operational Strain: a Study of COVID-19 Pandemic Caregivers and Military Personnel on Operational Missions |
Coronavirus disease 19 infection, Psychiatric disorder |
electrocardiogram alone, electrodermal activity alone, emotional stimulation assessment alone, saliva sampling alone, work-related stress assessment alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Direction Centrale du Service de Sante des Armees |
|
France |
2020-09-30 |
2021-02-28 |
2020-COVID19-28, COVID-TRUST, NCT04517136 |
Phase Not Applicable |
Not yet recruiting |
1 |
5 Months |
60 |
Damien CLAVERIE, MD, PhD, Khaldoun KUTEIFAN, MD |
2020-08-20 |
| fenix: Evaluation of symptoms, respiratory, pulmonary image and inflammation in patients who have been hospitalized for coronavirus infection in the period of a year, multicentric study |
Coronavirus disease 19 infection, Inflammatory disease, Respiratory disease |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Hospital Beneficiência Portuguesa de Bauru, Hospital Estadual Américo Brasiliense, Hospital Estadual de Bauru, Hospital Of Syrian Lebanese Itatiba S/C Ltd, Incor - Instituto do Coração do Hospital das Clínicas da FMUSP, Irmandade Santa Casa de Misericordia de Araraquara, Unidade de Pesquisa Clínica - Hospital das Clínicas da Faculdade de Medicina de Botucatu, Universidade Federal De Uberlândia - Ufu, Universidade Federal de Sao Paulo - UNIFESP, University Hospital of the Faculty of Medicine of Ribeirão Preto |
|
Brazil |
2020-06-02 |
|
A27072519840, CAAE:31258820.5.1001.5411, CEP: 4.015.191, CEP: 4.121.653, RBR-8j9kqy, fenix |
Phase Not Applicable |
Recruiting |
1 |
|
270 |
Andre Luis Pereira Alburquerque, Eloara Vieira Machado Ferreira Alvares, Suzana Erico Tanni Minamoto |
2020-08-27 |
| Intramuscular Effect of Polymerized Type I Collagen on the Cytokine Storm in COVID-19 Patients |
Coronavirus disease 19 infection, Inflammatory disease, Pulmonary fibrosis |
collagen-polyvinylpyrrolidone alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Instituto Nacional de Ciencias Medicas y Nutricion |
|
Mexico |
2020-08-19 |
2021-06-19 |
IRE-3412-20-21-1, NCT04517162 |
Phase 1 Clinical |
Not yet recruiting |
1 |
10 Months |
90 |
Daniel Azamar-Llamas, MD, Diego F Hernández-Ramírez, PhD, Elizabeth Olivares-Martínez, PhD, Enrique Ochoa-Hein, MD, Eric Ochoa-Hein, MD, Gonzalo Torres-Villalobos, MD, PhD, Janette Furuzawa Carballeda, Janette Furuzawa-Carballeda, PhD, Luis A Septien-Stute, MD |
2020-08-20 |
| canSEROcov: Study of the Specific Seroprevalence of SARS-CoV-2 in a Sample of Patients and Salaried Staff From a French Anti-cancer Center at the End of the Containment Period of the SARS-CoV-2 Pandemic |
Cancer, Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Georges-François Leclerc |
|
France |
2020-05-12 |
2020-06-30 |
2020-A00877-32, NCT04517097, canSEROcov |
Phase Not Applicable |
Completed |
1 |
1 Month |
1680 |
|
2020-08-21 |
| SeroCovEms: Study of SARS-CoV2 Virus (COVID-19) Seroprevalence Among Lyon-Bron Military Health Schools Personnel |
Coronavirus disease 19 infection |
Anti-SARS-CoV2 serology test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Direction Centrale du Service de Sante des Armees |
|
France |
2020-09-30 |
2020-11-30 |
2020-COVID19-29, NCT04516928, SeroCovEms |
Phase Not Applicable |
Not yet recruiting |
1 |
2 Months |
950 |
Annick BUZENS, MD, Christophe MARTINAUD, MD, PhD, Ludovic KARKOWSKI, MD |
2020-08-22 |
| A phase III trial of WHOOP, a wearable device to check on several daily health data in COVID-19 patients |
Coronavirus disease 19 infection |
WHOOP alone |
|
|
G42 Healthcare |
|
|
2020-07-16 |
|
|
Phase 3 Clinical |
Recruiting |
0 |
|
|
|
2020-08-21 |
| Clinical study to assess the safety and tolerability of administration, directly into a vein, of human umbilical cord and placental blood plasma (Plasmacord) in patients with Severe acute respiratory syndrome resulting from Sars-Cov-2 infection (fever, cough headache, muscle aches and difficulty breathing) |
Coronavirus disease 19 infection, Respiratory distress syndrome |
Plasmacord alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cryopraxis Criobiologia Ltda |
|
Brazil |
2020-07-20 |
|
32622920.5.0000.0070, 4.055.744, 4.122.919, RBR-4pfygr, U1111-1256-0705 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
|
10 |
Dayane Vila Nova, Elie Fiss, Maria Helena Nicola |
2020-08-20 |
| Halodine Nasal Antiseptic in Patients With COVID-19 |
Coronavirus disease 19 infection |
Povidone-Iodine Solution (Halodine LLC) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Halodine LLC |
|
|
2020-09-01 |
2020-12-31 |
HDN-N02-COV24A, NCT04517188 |
Phase 4 Clinical |
Not yet recruiting |
0 |
4 Months |
40 |
Samuel B Barone, MD, Samuel Barone, MD |
2020-08-21 |
| A Study of AK-119, Anti-CD73 Antibody, a Treatment for COVID-19, in Healthy Subjects |
Coronavirus disease 19 infection |
AK-119 alone |
CD73 antagonist |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Akesobio Pty Ltd |
Akeso Biopharma Inc |
New Zealand |
2020-09-30 |
2021-04-30 |
AK119-101, NCT04516564 |
Phase 1 Clinical |
Not yet recruiting |
1 |
7 Months |
32 |
Kon Yew Kwek |
2020-08-21 |
| An observational, retrospective study on the protective role of chronic treatment with direct oral anticoagulants in elderly patients with COVID-19 interstitial pneumonia |
Atrial fibrillation, Coronavirus disease 19 infection, Deep vein thrombosis, Heart disease, Lung embolism, Pneumonia |
apixaban alone, dabigatran etexilate mesylate alone, edoxaban alone, rivaroxaban alone |
Factor IIa antagonist, Factor Xa antagonist, Protease-activated receptor-1 antagonist |
Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Modena and Reggio Emilia |
|
Italy |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
70 |
|
2020-08-19 |
| A multicenter clinical trial to evaluate 10-min rapid point-of-care saliva-based test for detecting active SARS-CoV-2 infections |
Coronavirus disease 19 infection |
rapid point-of-care saliva-based test alone |
|
|
Todos Medical Ltd |
|
Israel |
|
|
|
Phase Not Applicable |
Recruiting |
2 |
|
|
|
2020-08-19 |
| A phase II/III trials to assess safety and efficacy of Dexaneurosone prophylaxis and treatment for early and moderate cases of Covid-19 |
Coronavirus disease 19 infection |
dexaneurosone alone |
|
|
Biomed Industries Inc |
|
|
|
|
|
Phase 2/Phase 3 Clinical |
Planned |
0 |
|
|
|
2020-08-19 |
| Phase III, Double-blind, Placebo-controlled Study of AZD-1222 for the Prevention of COVID-19 in Adults |
Coronavirus disease 19 infection |
AZD-1222 alone |
COVID19 Spike glycoprotein modulator |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
AstraZeneca plc |
Biomedical Advanced Research and Development Authority (BARDA), IQVIA RDS Pty Ltd, US Department of Health and Human Services |
US |
2020-08-17 |
2022-10-05 |
D8110C00001, NCT04516746 |
Phase 3 Clinical |
Not yet recruiting |
68 |
25 Months |
30000 |
Ann Falsey, MD, AstraZeneca Clinical Study Information Center, Dr. Eric Daar, Dr. Raphael Landovitz, Magda Sobieszczyk, MD |
2020-08-28 |
| A phase II/III trials to assess safety and efficacy of Biomedivir prophylaxis and treatment for early and moderate cases of Covid-19 |
Coronavirus disease 19 infection |
traneurocin + atazanavir (oral, COVID-19), NeuroActiva alone |
AMPA receptor modulator, HIV-1 protease inhibitor |
|
Biomed Industries Inc |
|
|
|
|
|
Phase 2/Phase 3 Clinical |
Planned |
0 |
|
|
|
2020-08-24 |
| Experience of Orthopedic and Spine Center Pakistan During COVID-19 |
Coronavirus disease 19 infection, Infectious arthritis, Injury, Spinal disease |
AD cage alone, Ilizarov alone, K wiring alone, acetabulum fixation alone, amputation alone, arthroplasty alone, arthroscopic anterior cruciate ligament reconstruction alone, arthrotomy alone, bilateral total hip replacement alone, bilateral total knee replacement alone, biopsy alone, bipolar hemiarthroplasty alone, cannulated screw fixator alone, disc excision alone, dura repair alone, dynamic compression plate alone, dynamic hip screw alone, elbow reconstruction alone, external fixator (AO Foundation) alone, implant removal alone, intramedullary nail alone, knee arthroscopy alone, lateral mass screw fixation alone, locking compression plate alone, meniscectomy alone, pelvic fixation alone, plaster of paris (POP) alone, posterior cervical decompression alone, tension band wiring technique alone, transpedicular screw fixation alone, unilateral total hip replacement alone, unilateral total knee replacement alone, vacuum assisted closure (VAC) dressing alone, wound wash alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ghurki Trust Teaching Hospital |
|
Pakistan |
2020-03-19 |
2020-08-15 |
30, NCT04516824 |
Phase Not Applicable |
Completed |
1 |
4 Months |
2160 |
Dr. Ashfaq Jadoon, Dr. Majid Cheema, Dr. Samreen Sadiq, Prof Amer Aziz, Prof Rizwan Akram, Prof. Atiq Uz Zaman, Prof. Ijaz Ahmad |
2020-08-20 |
| A phase II/III trials to assess safety and efficacy of Nanomedivir for prophylaxis and treatment for early and moderate cases of Covid-19 |
Coronavirus disease 19 infection |
Nanomedivir alone |
AMPA receptor modulator |
|
Biomed Industries Inc |
|
|
|
|
|
Phase 2/Phase 3 Clinical |
Planned |
0 |
|
|
|
2020-08-19 |
| A phase I single-IV administration ascending dose study to assess the safety and tolerability of HFB-30132A in healthy subjects |
Coronavirus disease 19 infection |
HFB-30132A alone |
Angiotensin converting enzyme 2 inhibitor, COVID19 Spike glycoprotein inhibitor |
Healthy volunteers accepted |
HiFiBio |
|
US |
|
|
|
Phase 1 Clinical |
Planned |
1 |
|
|
|
2020-08-28 |
| A Phase 1a study was to assess safety, tolerability and pharmacokinetics of remdesivir in healthy volunteers |
Coronavirus disease 19 infection |
remdesivir (inhalant solution, COVID-19), Gilead alone |
COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator |
Healthy volunteers accepted |
Gilead Sciences Inc |
|
US |
|
|
|
Phase 1b Clinical |
Not yet recruiting |
1 |
|
60 |
|
2020-08-19 |
| A case-report study of acute hemolysis induced by hydroxychloroquine in a patient with severe COVD-19 related lung injury |
Coronavirus disease 19 infection, Viral pneumonia |
hydroxychloroquine plus lopinavir + ritonavir |
HIV protease inhibitor |
Male, European Ancestry |
Universita di Verona |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
1 |
|
2020-08-19 |
| >A clinical trial of Sputnik V for the prevention of Covid-19 in Venezuela |
Coronavirus disease 19 infection |
Sputnik V alone |
COVID19 Spike glycoprotein modulator |
|
Venezuelan Institute of Scientific Investigations (IVIIC) |
|
Venezuela |
|
|
|
Phase Not Applicable |
Planned |
1 |
|
|
|
2020-08-19 |
| COVIDET: Assessment of SARS-CoV-2 Seroprevalence in Detention |
Coronavirus disease 19 infection |
venous blood test alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assistance Publique Hopitaux de Paris |
|
France |
2020-09-01 |
2021-01-01 |
APHP200667, COVIDET, NCT04516512 |
Phase Not Applicable |
Not yet recruiting |
1 |
4 Months |
2500 |
Anne Dulioust, MD, PhD, Anne Dulioust, MD,PHD, Anne Maie Roque-Afonso, MD, MPH, Guillaume Mellon, MD, MPH, Guillaume Mellon, MD,MPH |
2020-08-20 |
| Efficacy of L Plantarum and P Acidilactici in Adults With SARS-CoV-2 and COVID19 |
Coronavirus disease 19 infection, Dyspnea |
Variable regimens including Lactobacillus plantarum CECT 7484 , Lactobacillus plantarum CECT 7485 , Lactobacillus plantarum CECT7481 , P acidilactici CECT 7483 |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
AB Biotics |
Hospital General Dr. Manuel Gea González, Innovacion y Desarrollo de Estrategias en Salud |
|
2020-08-19 |
2021-01-31 |
ABB-COVID19, NCT04517422 |
Phase Not Applicable |
Not yet recruiting |
0 |
5 Months |
300 |
Pedro Gutierrez-Castrellon, MD, PhD |
2020-08-20 |
| Hydroxychloroquine ineffective as a preventive antiviral against COVID-19 patiients with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) |
Coronavirus disease 19 infection |
hydroxychloroquine alone |
|
|
Case Western Reserve University |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
159 |
Mendel Singer, PhD, MPH |
2020-08-19 |
| An observational, cautionary case report to evaluate the outcomes of tocilizumab therapy in patients with COVID-19-induced cytokine release syndrome |
Coronavirus disease 19 infection |
tocilizumab alone |
|
|
University of New Brunswick |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
2 |
|
2020-08-25 |
| SOBERANA 01: Phase I/II, randomized, controlled, adaptive, double-blind and multicenter study to evaluate the safety, reactogenicity and immunogenicity, of the prophylactic FINLAY-FR-1 anti-SARS-CoV-2 Vaccine Candidate in a two-doses schedule(COVID-19) |
Coronavirus disease 19 infection |
FINLAY-FR-1 anti-SARS-CoV-2 Vaccine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Finlay Institute |
|
Cuba |
2020-08-24 |
2021-01-11 |
IFV/COR/04, RPCEC00000332, SOBERANA 01 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
4 Months |
676 |
Beatriz Paredes Moreno, Meiby Rodríguez Gonzalez, Sonia Perez Rodriguez |
2020-08-20 |
| Developing the online program of SST |
Autism, Coronavirus disease 19 infection |
Online meeting system alone, Social skills training program alone |
|
Children (6-12 yrs) |
Osaka University |
|
Japan |
2020-08-15 |
|
UMIN000041437 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
TOMOKA YAMAMOTO |
2020-08-27 |
| Garlic and cinnamon on the treatment of patients with corona |
Coronavirus disease 19 infection |
cinnamon essential oil (Zardband pharmaceutical company) alone, garlic essential oil (Amin Pharmaceutical Company) alone |
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sabzevar University of Medical Sciences |
|
Iran |
2020-08-22 |
|
IRCT20200705048011N1, ir.medsab.rec.1399.072 |
Phase Not Applicable |
Recruiting |
1 |
|
45 |
Dr.Fereshte Ghorat, Nasrin Fazel |
2020-08-24 |
| Famotidine and COVID-19 |
Coronavirus disease 19 infection |
Variable regimens including atazanavir , atazanavir + ritonavir , chloroquine phosphate , famotidine (Chemidarou Pharmaceutical Company) , hydroxychloroquine sulfate , lopinavir + ritonavir |
HIV GAG POL polyprotein inhibitor, HIV GAG protein inhibitor, HIV protease inhibitor, HIV-1 protease inhibitor |
|
Bandare-abbas University of Medical Sciences |
|
Iran |
2020-06-21 |
|
IR.HUMS.REC.1399.255, IRCT20200509047364N2 |
Phase 3 Clinical |
Recruiting |
1 |
|
20 |
Dariush Hooshyar, Dr. Mehdi Hassaniazad, Dr. Mitra Kazemijahromi, Dr. Teamur Aghamolaei |
2020-08-19 |
| Giloy Gomutra Capsule, Asthi churna aur Kamdhenu Asava ka vaishvik mahamari Covid-19 par logo ka anubhav aur Chikitsakiya prabhava ka Ankalan |
Coronavirus disease 19 infection |
Variable regimens including Asthi Churna , Ayurvedic Giloy Gomutra , Kamdhenu Asava |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Bansi Gir Gaushala |
|
India |
2020-08-18 |
|
CTRI/2020/08/027083 |
Phase Not Applicable |
Not yet recruiting |
2 |
|
100 |
Dr Dineshchandra H Pandya, Dr Urvi Pandya |
2020-08-19 |
| Effects of chest physiotherapy in COVID-19 patients with respiratory infection |
Coronavirus disease 19 infection, Respiratory tract infection |
chest physiotherapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Semnan University of Medical Sciences |
|
Iran |
2020-09-20 |
|
IR.SEMUMS.REC.1399.111, IRCT20160808029264N9 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
44 |
Dr Parviz Kokhaei, Dr Rasool Bagheri, Dr. Mohammad Memarian |
2020-08-19 |
| Efficacy of N-acetylcysteine in patients with COVID-19 |
Coronavirus disease 19 infection |
Variable regimens including N-acetylcysteine , atazanavir + ritonavir , hydroxychloroquine , lopinavir + ritonavir |
HIV protease inhibitor |
|
Iran University of Medical Sciences |
|
Iran |
2020-05-21 |
|
IR.IUMS.REC.1399.206, IRCT20200623047897N1 |
Phase 3 Clinical |
No longer recruiting |
1 |
|
60 |
Dr. Seyyed Abbas Motevalian, Najmolsadat Atefi, Niloufar Najar Nobari |
2020-08-24 |
| COSMIC-19: Investigating the impact of coronavirus infection (COVID-19) on cardiovascular injury using multiple imaging methods |
Cardiovascular injury, Coronavirus disease 19 infection |
CT coronary angiogram alone, PET scan alone, cardiac MRI alone, flurodeoxyglucose alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Aga Khan University Hospital |
United Kingdom Research & Innovation |
Kenya |
2020-03-23 |
|
2020/IERC-74, COSMIC-19, ISRCTN12154994 |
Phase Not Applicable |
Recruiting |
1 |
|
50 |
Dr Anoop Shah, Dr Shirjel Alam |
2020-08-19 |
| Home Management of Adult Egyptian Mild COVID-19 Cases |
Coronavirus disease 19 infection |
telemedicine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Cairo University |
|
Egypt |
2020-07-01 |
2021-03-31 |
NCT04515199, TELEMEDICINE IN MILD COVID-19 |
Phase Not Applicable |
Recruiting |
1 |
9 Months |
400 |
Ibrahim El Ebrashy, Professor, Maha Hossam Al-Din Ibrahim, Professor, Mohamed Tharwat Hegazy, Mohamed Tharwat Hegazy, Lecturer |
2020-08-19 |
| UNITY Global: An International Registry of Healthcare Workers to Collect Information on Risk Factors for Developing COVID-19 and the use of preventative therapies |
Coronavirus disease 19 infection |
|
|
|
Certara |
COVID -19 Therapeutics Accelerator |
Uganda, South Africa, Pakistan, Zimbabwe, Nigeria, Senegal, Zambia, Kenya |
2020-08-03 |
|
UNITY Global |
Phase Not Applicable |
Recruiting |
8 |
|
10000 |
Craig Rayner, Roman Casciano |
2020-08-18 |
| A Dose-Confirmation Study to Evaluate the Safety, Reactogenicity and Immunogenicity of Vaccine CVnCoV in Healthy Adults |
Coronavirus disease 19 infection |
SARS-CoV-2 mRNA vaccine (COVID-19), CureVac alone |
COVID19 Spike glycoprotein modulator |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
CureVac AG |
|
|
2020-08-17 |
2021-11-09 |
CV-NCOV-002, NCT04515147 |
Phase 2 Clinical |
Not yet recruiting |
0 |
14 Months |
691 |
Clinical Trial Information |
2020-08-19 |
| Perinatal Outcomes and Hematological Parameters in COVID-19 Pregnancies |
Coronavirus disease 19 infection, Pregnancy disorder |
|
|
Healthy volunteers accepted, Female, Young Adults (18-44 yrs) |
Ankara City Hospital Bilkent |
|
Turkey |
2020-03-10 |
2020-08-10 |
E1-20-672, NCT04515108 |
Phase Not Applicable |
Completed |
1 |
5 Months |
108 |
Esin Merve Erol Koç, MD |
2020-08-21 |
| To assess the fear and readiness of medical workers to work in the health care set up in the state of Karnataka during COVID-19 illness after the lock down is over |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Kasturba Medical College, Manipal |
|
India |
2020-08-18 |
|
CTRI/2020/08/027082 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
600 |
Dr Sadhana N Holla, Prabhleen Kaur Sibal |
2020-08-19 |
| Elevated fibrinogen and fibrin degradation product were associated with poor outcome in COVID-19 patients |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Faculty of Medicine Airlangga University |
|
Indonesia |
2020-05-05 |
|
UMIN000041428 |
Phase Not Applicable |
Completed |
1 |
|
1654 |
Johannes Nugroho, Maya Ayun |
2020-08-26 |
| END CoV-2: Novel Point-of-Care Diagnostic Test for SARS-CoV-2 (COVID-19) |
Coronavirus disease 19 infection |
Biospecimen Collection (nasopharyngeal sample) alone, Questionnaire Administration alone |
|
Healthy volunteers accepted |
MD Anderson Cancer Center |
National Cancer Institute, Rice University |
US |
2020-04-09 |
2021-04-30 |
2020-0318, 2020-0318, END CoV-2, NCI-2020-03470, NCT04513990 |
Phase Not Applicable |
Recruiting |
2 |
12 Months |
1500 |
Kathleen M Schmeler, Kathleen M. Schmeler |
2020-08-20 |
| PENFS COVID-19: Neuromodulation With Percutaneous Electrical Nerve Field Stimulation for Adults With COVID-19 |
Coronavirus disease 19 infection, Dyspnea, Viral pneumonia |
Auricular percutaneous neurostimulation alone, Neuro-Stim System (NSS)-2 BRIDGE alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Olive View-UCLA Education and Research Institute |
|
US |
2020-07-13 |
2021-07-31 |
1600899, NCT04514627, PENFS COVID-19 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
100 |
Nader Kamangar, M.D., Rajan Saggar, M.D. |
2020-08-20 |
| Safety and efficacy of citrobioShield product in improving immunity in COVID-19 patients via inhalation |
Coronavirus disease 19 infection |
CitrobioSheild alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
GERMKILL INDIA |
|
India |
2020-08-17 |
|
CTRI/2020/08/027085 |
Phase Not Applicable |
Recruiting |
1 |
|
20 |
Dr Himanshu Pophale, Dr R Nagaraja Naidu, Subham Dutta |
2020-08-19 |
| SeCoVIHA: COVID-19 Prevalence in HIV-infected Patients |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hopitaux Universitaires de Strasbourg |
|
|
2020-09-15 |
2020-09-15 |
7947, NCT04515225, SeCoVIHA |
Phase Not Applicable |
Not yet recruiting |
0 |
|
500 |
|
2020-08-19 |
| Comparision of two barrier devices for placement of tube into trachea(windpipe)in COVID-19 patients |
Coronavirus disease 19 infection |
Acrylic box alone, Plastic drape alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Gujarat Cancer Society Medical college hospital and research centre |
|
India |
2020-08-17 |
|
CTRI/2020/08/027081 |
Phase 4 Clinical |
Not yet recruiting |
1 |
|
500 |
Dr Heena Chhanwal |
2020-08-19 |
| Melatonin in COVID-19 |
Coronavirus disease 19 infection, Lung disease |
hydroxychloroquine sulfate (Amin Pharmaceutical company) plus melatonin (Vana Darou Gostar Pharmaceutical Company) |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Bandare-abbas University of Medical Sciences |
|
Iran |
2020-08-22 |
|
IR.HUMS.REC.1399.250, IRCT20200506047323N5 |
Phase 3 Clinical |
Recruiting |
1 |
|
60 |
Mohammad Fathalipour, Parivash Davoodian, Teamur Aghamolaei |
2020-08-24 |
| Evaluation the efficacy of Curcuden 35 in patients with COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
Curcuden 35 (Alborz Nanomed-Tech Company) alone, national guideline based COVID-19 treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shaheed Beheshti Medical University |
Alborz Nanomed-Tech Company, Mobtaker Electric Company (METEC) |
Iran |
2020-05-21 |
|
IR.SBMU.RETECH.REC.1399.085, IRCT20170128032241N3 |
Phase 3 Clinical |
Recruiting |
1 |
|
20 |
Maria Tavakoli Ardakani, Maryam Mohajeri, Mehran Azodi, Narges Shakeri, ماریا توکلی اردکانی |
2020-08-20 |
| A clinical trial of K-NK-ID101 cell therapy for the potential treatment of COVID-19 |
Coronavirus disease 19 infection |
K-NK-ID101 cell therapy alone |
|
|
Kiadis Pharma BV |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-08-18 |
| Evaluate the medicinal effects of both Ayurveda combinations Bio-Immune as Anti-viral and Covalix Vaccoil as alternate to Vaccine of COVID-19 on exposed individuals and Covid19 contact |
Coronavirus disease 19 infection |
Bio-Immune powder alone, Covalix Vaccoil liquid alone |
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Leaf BioLab Leaf Research Institute |
|
India |
2020-08-20 |
|
BICV19P, CTRI/2020/08/027084, U1111-1256-7669 |
Phase Not Applicable |
Not yet recruiting |
2 |
|
61000 |
AMIT DUTTA |
2020-08-19 |
| A randomized, double-blind, placebo-controlled pilot clinical study to evaluate ensifentrine delivered via pressurized metered-dose inhaler ("pMDI") formulation as a treatment for patients hospitalized with COVID-19 |
Coronavirus disease 19 infection |
ensifentrine (DPI/MDI, respiratory diseases), Verona Pharma alone |
PDE 3 inhibitor, PDE 4 inhibitor |
|
Verona Pharma plc |
|
US |
|
|
|
Phase Not Applicable |
Planned |
1 |
|
|
|
2020-08-24 |
| Covae: Assessment of the Prevalence and the Impact of the COVID-19 Epidemic in the French Flight Crew in 2020 |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Direction Centrale du Service de Sante des Armees |
|
France |
2020-09-30 |
2020-12-31 |
2020-COVID19-26, Covae, NCT04514874 |
Phase Not Applicable |
Not yet recruiting |
2 |
3 Months |
500 |
Marc MONTEIL, MD, Sébastien BISCONTE, MD |
2020-08-20 |
| A clinical trial of Sputnik V for the prevention of Coronavirus disease 19 infection |
Coronavirus disease 19 infection |
Sputnik V alone |
COVID19 Spike glycoprotein modulator |
|
Instituto De Tecnologia Do Parana of Brazil |
Russian Direct Investment Fund |
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-08-24 |
| A phase IIa clinical trial to assess teh efficacy of NVX-CoV2373, Novavax COVID-19 vaccine candidate |
Coronavirus disease 19 infection |
NVX-CoV2373 alone |
COVID19 Spike glycoprotein modulator |
|
Novavax Inc |
Bill & Melinda Gates Foundation |
South Africa |
|
|
|
Phase 2b Clinical |
Recruiting |
1 |
|
2665 |
Gregory M. Glenn, Shabir Madhi |
2020-08-24 |
| A phase II/III study to evaluate TLC-19 in patients with coronavirus disease 2019 (COVID-19) |
Coronavirus disease 19 infection |
TLC-19 alone |
|
|
Taiwan Liposome Co |
|
US |
|
|
|
Phase 2/Phase 3 Clinical |
Planned |
1 |
|
|
|
2020-08-18 |
| Benefit and Harm of Angiotensin Converting Enzyme Inhibitor and Angiotensin Receptor Blocker in COVID-19 Patients: A Review Protocol of Systematic Review and Meta-Analysis |
Acute lung injury, Cardiac failure, Cardiovascular disease, Coronavirus disease 19 infection, Myocardial infarction, Myocarditis, Stroke |
ARB therapy alone, Angiotensin Converting Enzyme Inhibitor therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universitas Airlangga |
|
Indonesia, Asia |
2020-07-30 |
|
UMIN000041430 |
Phase Not Applicable |
Recruiting |
1 |
|
|
Eka Utami, Johanes Nugroho |
2020-08-20 |
| A phase I trial to evaluate the pharmacokinetic and safety of TLC-19 in healthy subjects |
Coronavirus disease 19 infection |
TLC-19 alone |
|
Healthy volunteers accepted |
Taiwan Liposome Co |
|
Taiwan |
|
|
|
Phase 1 Clinical |
Planned |
1 |
|
|
|
2020-08-18 |
| Prognostic role of coagulation profiles in predicting in-hospital mortality of COVID-19 patients: a meta-analysis |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Faculty of Medicine Airlangga University |
|
Indonesia, Asia |
2020-07-16 |
|
UMIN000041427 |
Phase Not Applicable |
Recruiting |
1 |
|
8397 |
Eka Mulia, Johanes Nugroho |
2020-08-20 |
| The role of markers (NLR, IL-6, D-dimer) in COVID-19 patients and it’s co-relationship with oxygenation - retrospective, observational study in Tertiary care COVID ICU |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Vardhman Mahavir Medical College & Safdarjung Hospital |
|
India |
2020-08-22 |
|
CTRI/2020/08/027110 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
250 |
Arin Choudhury |
2020-08-19 |
| Effect of N95 mask in our body study in high volume center |
Coronavirus disease 19 infection |
N95-mask alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Vardhman Mahavir Medical College & Safdarjung Hospital |
|
India |
2020-08-18 |
|
CTRI/2020/08/027112 |
Phase Not Applicable |
No longer recruiting |
1 |
|
|
Arin Choudhury |
2020-08-18 |
| Personal Experience During COVID-19 Pandemic |
Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sri Ramachandra Institute of Higher Education and Research |
|
India |
2020-08-22 |
|
CTRI/2020/08/027118 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1000 |
Dr D Rohith Khanna, Dr Vivian Kapil V |
2020-08-19 |
| A clinical trial to know the efficacy and safety of herbal product Virowin in combination with Energy-Z capsule in treating mild to moderate COVID-19 patients |
Coronavirus disease 19 infection |
Energy Z capsules plus Virowin |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Amulya Herbs |
|
India |
2020-08-20 |
|
CTRI/2020/08/027120, PHAR/CT/Virowin/14072020/01, VERSION 01 |
Phase 4 Clinical |
Not yet recruiting |
1 |
|
|
Baburao Vikram, Dr K Sunil Naik, Dr Parikshit Bansal |
2020-08-19 |
| A Clinical Study to Understand the Effect of Inosine Pranobex in COVID-19 Patients when used along with the Standard of Care in COVID Patients |
Coronavirus disease 19 infection |
inosine pranobex alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Themis Medicare Ltd |
|
India |
2020-08-20 |
|
CTRI/2020/08/027162, TML/IAD/2020/01 Version 1.1 |
Phase 2 Clinical |
Not yet recruiting |
5 |
|
60 |
Dr Ashok Kumar Swain, Dr Dnyaneshwar Halnor, Dr Jayanthi C R, Dr Mohammad Siddiqui, Dr Padmaja Saraf, Dr Ranganath T Ganga, Mr Sangameshwar Iyer |
2020-08-20 |
| COViPP: The COVID-19 Outbreak in Pasir Puteh District in Kelantan, Malaysia: An Overview |
Coronavirus disease 19 infection |
|
|
|
PEJABAT KESIHATAN DAERAH PASIR PUTEH |
|
Malaysia |
2020-08-15 |
2020-09-19 |
54847, COViPP, NMRR-20-1734-54847, PKDPP2020/1 |
Phase Not Applicable |
Status not specified |
1 |
1 Month |
|
Doctor Teh Muthmainnah Binti Md Suhaimi |
2020-08-20 |
| Cross-Sectional CFAR HIV/COVID Study |
Coronavirus disease 19 infection, HIV infection |
COVID-19 specific antibody testing alone, real-time polymerase chain reaction assay alone |
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
University of Miami |
Miami Center for AIDS Research |
US |
2020-08-12 |
2021-03-31 |
20200802, NCT04514016 |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
100 |
Adriana Drada, CRC, Charles Mitchell, MD, Grace Alvarez, CRC |
2020-08-19 |
| Randomized Clinical Trial of Intranasal Dexamethasone as an Adjuvant in Patients With COVID-19 |
Coronavirus disease 19 infection, Interstitial lung disease, Respiratory disease, Respiratory distress syndrome, Viral pneumonia |
dexamethasone alone, standard care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Universidad Nacional Autonoma De Mexico |
Hospital General de Mexico, Instituto Nacional De Neurología Y Neurocirugía Manuel Velasco Suárez, Instituto Nacional de Cardiologia Ignacio Chavez |
Mexico |
2020-08-31 |
2020-12-31 |
DI/20/407/04/36, NCT04513184 |
Phase 2 Clinical |
Recruiting |
4 |
4 Months |
60 |
Ana María H Espinosa-García, PhD, Edda Sciutto, PhD, Graciela A Cárdenas-Hernández, PhD, Graciela Cárdenas-Hernández, PhD, Joselín Hernández-Ruiz, PhD, María Chavez-Canales, PhD, María Chávez-Canales, PhD |
2020-08-24 |
| Convalescent Plasma in the Early Treatment of High-Risk Patients With SARS-CoV-2 (COVID-19) Infection |
Coronavirus disease 19 infection, Multiple organ failure, Respiratory failure, Septic shock |
convalescent plasma cells alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Norton HealthCare US |
|
US |
2020-08-14 |
2021-12-31 |
20-N0124, NCT04513158 |
Phase 2 Clinical |
Recruiting |
4 |
16 Months |
100 |
Don A Stevens, MD, Jackie Bourke, RN, Jayne Carwile, RN, MSN, Joseph J Maly, MD, Joseph M Flynn, DO, MPH, Khuda D Khan, MD, PhD, Marti Gardner, MSN, APRN, Paul Schulz, MD |
2020-08-26 |
| To Evaluate Efficacy And Safety Of 'viracide' In The Management Of Corona Virus Disease 2019 (Covid-19) |
Coronavirus disease 19 infection |
SOC Therapy alone, Viracide alone |
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Smt Kashibai Navale Medical College and Hospital |
|
India |
2020-08-20 |
|
CTRI/2020/08/027106 |
Phase Not Applicable |
Not yet recruiting |
2 |
|
120 |
Dr Shreepad Bhat, Dr Vikas Deshmukh, Mr Sohal Pendse |
2020-08-20 |
| Cross Sectional Retrospective Analysis Of Clinical Sign Of Breathlessness In Sitting And Supine Position In COVID-19 Patients |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Seth GS Medical College |
|
India |
2020-08-13 |
|
CTRI/2020/08/027104, EC/OA-114/2020 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
45 |
Dr Amita Athavale |
2020-08-20 |
| Novel Safe Transport Medium and Rapid RNA Extraction Method for COVID-19 |
Coronavirus disease 19 infection |
Rapid Solution-Based RNA Extraction Method alone |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
B. J. Medical College, Pune, BioEra Life Sciences Pvt Ltd |
|
India |
2020-08-19 |
|
CTRI/2020/08/027103 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Dr Rajesh Karyakarte |
2020-08-19 |
| Colchichine use for preventing COVID infection in hemodialysis patients |
Coronavirus disease 19 infection |
colchicine alone, dialysis alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Narayana Hrudayalaya LTD |
|
India |
2020-08-15 |
|
CTRI/2020/08/027102 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
100 |
Dr Krishna Kishore C, DrAlben Sigamani |
2020-08-20 |
| Role of Digital communication in COVID-19 isolation facilities an observation study |
Coronavirus disease 19 infection |
internet based audio-visual communication alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
National Cancer Institute, Jhajjar, AIIMS |
|
India |
2020-09-01 |
|
CTRI/2020/08/027094 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Dr Brajesh Kumar Ratre |
2020-08-20 |
| DPC19 study: Disease Profile of Covid-19 in patients admitted at AIIMS, Rishikesh |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
All India Institute Of Medical Sciences, Rishikesh |
|
India |
2020-08-25 |
|
CTRI/2020/08/027169, DPC19 study |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1000 |
Prasan Kumar Panda |
2020-08-18 |
| Clinical profile of neonates born to mothers with COVID-19 |
Coronavirus disease 19 infection |
RT-PCR of Naso pharyngeal swab alone |
|
Newborn Infants (up to 5 months) |
Government Medical College Kannur |
|
India |
2020-08-30 |
|
CTRI/2020/08/027175 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
50 |
Ambili Susan Jacob |
2020-08-18 |
| Clinical trial study to investigate safety and efficacy of ImmunoSEB and ProbioSEB |
Coronavirus disease 19 infection |
ImmunoSEB Capsule plus ProbioSEB CSC3 Capsule |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
SRV Hospital |
|
India |
2020-08-21 |
|
CTRI/2020/08/027168, PROCLIN_COVID-005 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
60 |
Dr Abhay Vispute Shantaram |
2020-08-18 |
| Psychological Impact of COVID 19 on frontline health care workers |
Acute stress disorder, Coronavirus disease 19 infection, Psychiatric disorder |
PPE KIt alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
AIIMS Jodhpur |
|
India |
2020-08-20 |
|
CTRI/2020/08/027174 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
500 |
KAMLESH KUMARI |
2020-08-18 |
| A randomized, double-blind, placebo-controlled, phase III clinical trial to evaluate the efficacy of NVX-CoV2373 for treatment of COVID-19 |
Coronavirus disease 19 infection |
NVX-CoV2373 alone |
COVID19 Spike glycoprotein modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Novavax Inc |
UK Government |
UK |
2020-09-30 |
|
|
Phase 3 Clinical |
Planned |
1 |
|
9000 |
|
2020-08-24 |
| Study of stress, depression and anxiety in healthcare workers doing COVID duty |
Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Gujarat Cancer Society Medical college hospital and research centre |
|
India |
2020-08-18 |
|
CTRI/2020/08/027166 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
200 |
Aatman Parikh |
2020-08-18 |
| Necessary measures taken for covid positive pregnant women during pandemic |
Coronavirus disease 19 infection |
|
|
Female, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Sri B. M. Patil Medical College |
|
India |
2020-08-15 |
|
CTRI/2020/08/027173 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
DR SHREEDEVI KORI |
2020-08-19 |
| Clinical Profile and Outcome of Neonates Born to Mothers with COVID in a Tertiary Care Centre |
Coronavirus disease 19 infection |
|
|
Newborn Infants (up to 5 months) |
Sri Ramachandra Institute of Higher Education and Research |
|
India |
2020-08-16 |
|
CTRI/2020/08/027172 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
40 |
Dr Thinesh Kumar J |
2020-08-19 |
| Safety and Efficacy of Anti-SARS-CoV-2 Equine Antibody Fragments (INOSARS) for Hospitalized Patients With COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
anti-SARS-CoV-2 immunoglobulin F(ab')2 fragment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital San Jose Tec de Monterrey |
|
Mexico |
2020-10-20 |
2021-06-20 |
INOSARS-COV-2 TECSALUD, NCT04514302 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
8 Months |
51 |
Alejandro Torres-Quintanilla, MD, MSc, José F Castilleja-Leal, MD, Servando Cardona-Huerta, MD, Ph. D. |
2020-08-18 |
| COVITA: The Corona and COVID-19 Study in Telemark and Agder |
Coronavirus disease 19 infection |
antibody testing alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sykehuset Telemark |
Aalborg Universitet, London School of Hygiene and Tropical Medicine, Norwegian Institute of Public Health, Sykehuset Sorlandet Hf, Universiteit Leiden |
Norway |
2020-07-01 |
2035-12-31 |
COVITA, COVITA, NCT04514003 |
Phase Not Applicable |
Recruiting |
1 |
186 Months |
5000 |
Anne Kristin M. Fell, PhD |
2020-08-19 |
| COVID-19 Global Rheumatology Alliance |
Coronavirus disease 19 infection, Rheumatoid arthritis |
|
|
|
University of California |
|
Iran, Sweden, Brazil, Germany, Canada, New Zealand, Mexico, Algeria, Argentina, India, Australia, Norway, Iceland, Belgium, UK, Italy, France, Finland, Austria, Chile, Denmark, Czech Republic, US, Egypt |
2020-03-16 |
|
CTRI/2020/08/027165 |
Phase Not Applicable |
Not yet recruiting |
26 |
|
3000 |
Dr Amita, Sharath Kumar |
2020-08-18 |
| National Clinical Registry of COVID 19 |
Coronavirus disease 19 infection |
|
|
|
Indian Council of Medical Research |
|
India |
2020-08-17 |
|
CTRI/2020/08/027164 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
10000 |
Dr Anup Agarwal, Dr Aparna Mukherjee |
2020-08-18 |
| BRICOAKI TRIAL: Measurement of renal biomarker in COVID-19 associated acute renal failure |
Coronavirus disease 19 infection, Renal injury |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
All India Institute of Medical Sciences Patna |
|
India |
2020-08-25 |
|
BRICOAKI TRIAL, CTRI/2020/08/027171 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
75 |
Neeraj Kumar |
2020-08-21 |
| Study to check the safety and immune response of a COVID-19 vaccine in healthy Indian adults |
Coronavirus disease 19 infection |
Covishield (SII-ChAdOx1 nCoV-19) alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Serum Institute of India Ltd |
Indian Council of Medical Research |
India |
2020-08-24 |
|
CTRI/2020/08/027170, ICMR/SII-COVISHIELD |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
17 |
|
1600 |
Dr Ashish Bavdekar, Dr B Devi Madhavi, Dr B S Garg, Dr Kamran Zaman, Dr Kiranjit Singh, Dr Krishna Pandey, Dr Madhu Gupta, Dr Muralidhar Tambe, Dr Nithya Gogtay, Dr Pankaja Raghav, Dr Prasad Kulkarni, Dr Praveen Kulkarni, Dr Ramkrishnan, Dr Randeep Guleria, Dr Renuka Munshi, Dr Sanjay Lalwani, Dr Sushant Meshram, Dr T S Selvavinayagam |
2020-08-23 |
| Pso-Vac: Educational Needs On Vaccines for Biological Patients With Psoriasis |
Coronavirus disease 19 infection, Psoriasis |
biological therapy alone, vaccine education alone |
|
|
Dermatrials Research |
|
Canada |
2020-08-13 |
2020-10-13 |
NCT04513847, PSO-VAC, Pso-Vac |
Phase Not Applicable |
Not yet recruiting |
1 |
2 Months |
1000 |
Heather Le, Ronald Vender MD FRCPC |
2020-08-19 |
| Ashwagandha in the prevention of COVID-19 in Health Care workers |
Coronavirus disease 19 infection |
Ashwagandha alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Central Council for Research in Ayurvedic Sciences, Ministry of Ayush |
|
India |
2020-08-23 |
|
AYUSH- CRD-HCW-01, CTRI/2020/08/027163 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
400 |
Dr Arvind Chopra, Dr Dilip Gode |
2020-08-19 |
| Benefit of positioning in COVID-19 patient on Bipap mechnical support |
Coronavirus disease 19 infection |
Bipap ventilator alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Gujarat Cancer Society Medical college hospital and research centre |
|
India |
2020-08-15 |
|
CTRI/2020/08/027080 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
100 |
Dr Carolin Smita Kerketta |
2020-08-18 |
| Study of lab investigations among hospitalized COVID-19 patients |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sri Ramachandra Institute of Higher Education and Research |
|
India |
2020-08-17 |
|
CTRI/2020/08/027079 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1000 |
Dr Swathy Moorthy, DrSPThiagarajan |
2020-08-18 |
| A randomized, double-blind, placebo-controlled, phase I clinical trial for evaluation of the safety and tolerability of recombinant novel coronavirus vaccines (CHO cells) in healthy people aged 60 years and above |
Coronavirus disease 19 infection, Viral pneumonia |
new coronavirus vaccines (CHO cells) alone |
|
Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hunan Province Centers for Disease Control and Prevention |
|
China |
2020-08-20 |
2020-12-31 |
ChiCTR2000035691 |
Phase 1 Clinical |
Not yet recruiting |
1 |
4 Months |
50 |
Li Fangjun, Zhong Zaixin |
2020-08-19 |
| Establishment of surveillance system for individuals diagnosed with COVID-19 |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Tata Memorial Centre |
|
India |
2020-08-17 |
|
CTRI/2020/08/027078 |
Phase Not Applicable |
Not yet recruiting |
2 |
|
1200 |
Dr Rajesh Dikshit |
2020-08-19 |
| Investigator Initiated Study to see the safety and efficacy of adding Thymosin Alpha to existing standard of care in severe COVID patients |
Coronavirus disease 19 infection |
Standard of Care alone, Thymosin alpha alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fortis hospital |
|
India |
2020-08-13 |
|
CTRI/2020/08/027061, IITTHY00120 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
15 |
Dr Adarsh Shetty, Dr Rahul pandit |
2020-08-18 |
| CONFIMID: Evaluation of the Impact of Lock Down and End of Lock Down on the Management of Patients With Inflammatory and Dysimmune Diseases Followed in the Context of IMMINeNT FHU (Rheumatology, Dermatology, Internal Medicine, Pneumology, Gastroenterology, Neurology) |
Angioedema, Ankylosing spondylitis, Asthma, Atopic dermatitis, Autoimmune disease, Coronavirus disease 19 infection, Crohns disease, Inflammatory disease, Multiple sclerosis, Psoriasis, Rheumatoid arthritis, Scleroderma, Systemic lupus erythematosus, Ulcerative colitis |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Regional Universitaire de Lille |
|
France |
2020-09-30 |
2020-11-30 |
2020_51, 2020_A01596_33, CONFIMID, NCT04513561 |
Phase Not Applicable |
Not yet recruiting |
1 |
2 Months |
4500 |
Frédéric DEZOTEUX, MD |
2020-08-19 |
| REACARDIOCOVID: Impact of COVID-19 on the Benefit of Cardiac Rehabilitation |
Coronavirus disease 19 infection, Heart injury |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Groupe Hospitalier Paris Saint-Joseph |
|
France |
2020-09-01 |
2021-06-30 |
NCT04513964, REACARDIOCOVID, READCARDIOCOVID |
Phase Not Applicable |
Not yet recruiting |
1 |
10 Months |
60 |
BEAUSSIER Helene, PharmD, pHD, DUC Philippe, MD, Iliou Marie-Christine, MD |
2020-08-19 |
| Telemedicine in HIV Care in Buenos Aires |
Coronavirus disease 19 infection, HIV infection |
Videoconsult through telemedicine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fundacion Ibis , Argentina |
|
Argentina |
2020-09-01 |
2022-07-01 |
NCT04513496, TM HIV BA |
Phase Not Applicable |
Not yet recruiting |
1 |
22 Months |
4000 |
|
2020-08-18 |
| Clinical study of safety, tolerance, and pharmacokinetics of nebulizer (INF-K + anti-inflammatory factor TFF2) in healthy volunteers and exploration of PK/PD fitting modeling in clinical trials of COVID-19 patients |
Coronavirus disease 19 infection, Viral pneumonia |
IFN/TFF2 alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Shanghai Public Health Clinical Center |
|
China |
2020-11-02 |
2023-08-13 |
ChiCTR2000035633 |
Phase 0 Clinical |
Not yet recruiting |
1 |
33 Months |
32 |
Jianqing Xu, Yan Liu |
2020-08-20 |
| Allocetra-OTS in COVID-19 |
Coronavirus disease 19 infection, Multiple organ failure, Respiratory disease |
Variable regimens including Allocetra , dexamethasone , enoxaparin sodium , remdesivir |
COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, Low molecular weight heparin, RNA polymerase modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hadassah Medical Organization |
|
Israel |
2020-08-01 |
2021-02-28 |
DM003, NCT04513470 |
Phase 1 Clinical |
Recruiting |
1 |
7 Months |
5 |
Dror Mevorach, MD, Peter V van Heerden, MD |
2020-08-19 |
| DEXTERITY Fitbit Pilot Study: Detecting Exacerbation Early Signs of SARS-CoV-2 infection by Fitbit: Pilot Study |
Coronavirus disease 19 infection |
fitbit Charge3 alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fitbit, Kanazawa University |
|
Japan |
2020-08-14 |
|
DEXTERITY Fitbit Pilot Study, UMIN000041421 |
Phase Not Applicable |
Recruiting |
2 |
|
30 |
Akihiro Nomura |
2020-08-20 |
| A Practical, Pilot, Randomized, Controlled Trial of Valproate Alone or in Combination With Quetiapine for Severe COVID-19 Pneumonia With Agitated Delirium |
Agitation, Coronavirus disease 19 infection, Delirium, Viral pneumonia |
Variable regimens including dexmedetomidine , divalproex sodium (oral extended-release), Sanofi , ketamine , midazolam hydrochloride , propofol, AstraZeneca/Fresenius , quetiapine IR |
5-HT 2 receptor antagonist, Alpha 2 adrenoceptor agonist, Benzodiazepine receptor agonist, CDKN1A gene modulator, Dopamine D2 receptor antagonist, GABA receptor agonist, Sodium channel inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Miami |
|
US |
2020-09-01 |
2021-09-01 |
20200851, NCT04513314 |
Phase 4 Clinical |
Not yet recruiting |
1 |
12 Months |
20 |
Dominique L Musselman, Dominique L Musselman, MD, Dominique Musselman, MD, Sergey Gerasim, MD |
2020-08-18 |
| Reliability of Standardized Protocol of Ultrasound of the Lungs in Prediction of Severity of Covid 19-infection |
Coronavirus disease 19 infection, Lung disease, Viral pneumonia |
ultrasound alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Jagiellonian University |
|
Poland |
2020-11-01 |
2022-02-28 |
JAGIELLONIANU67, NCT04513210 |
Phase Not Applicable |
Not yet recruiting |
1 |
16 Months |
300 |
Jakub M Antczak, MD, Wojciech Jagiełło, MD |
2020-08-19 |
| A Digital Companion for Loneliness During the COVID-19 Pandemic: A Feasibility Study |
Acute stress disorder, Coronavirus disease 19 infection, Psychiatric disorder |
animated, embodied conversational agent alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Soul Machines Ltd, University of Auckland |
|
New Zealand |
2020-08-24 |
2020-10-12 |
ACTRN12620000786998, U1111-1252-6680 |
Phase Not Applicable |
Not yet recruiting |
2 |
1 Month |
30 |
Prof Elizabeth Broadbent |
2020-08-31 |
| AFTERCOR: Long-term Impact in Intensive Care Survivors of Coronavirus disease-19 (COVID-19) |
Cognitive disorder, Coronavirus disease 19 infection, Depression |
Pulmonary function tests alone, blood draw alone, questionnaires alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The Prince Charles Hospital |
Wesley Research Institute |
South Africa, Italy, Hong Kong, Argentina, Ireland, Japan, Brazil, Spain, Germany, Australia, US |
2020-08-25 |
2022-12-31 |
ACTRN12620000799954, AFTERCOR |
Phase Not Applicable |
Not yet recruiting |
13 |
28 Months |
200 |
A/Prof Gianluigi Libassi, Dr Karin Wildi |
2020-08-31 |
| Early prone position in patients on spontaneous ventilation |
Coronavirus disease 19 infection, Respiratory insufficiency |
early prone position alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
BAHIA SECRETARIA DE SAUDE DO ESTADO, Hospital Geral Roberto Santos |
|
Brazil |
2020-07-15 |
|
34357020.5.0000.5028, 4.149.561, RBR-7d7ngw, U1111-1255-3761 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
|
88 |
Cicero Fontenelle, Jorge Luis Motta Dos Anjos, Ludmilla Campos Gaspar |
2020-08-24 |
| A retrospective study to analyze epidemiological and clinical characteristics of persistently asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) carriers |
Coronavirus disease 19 infection |
Clinical characteristic analysis alone |
|
|
Zhengzhou University |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
26 |
|
2020-08-18 |
| MET-Covid: Metformin for Prevention and Outpatient Treatment of COVID-19 |
Coronavirus disease 19 infection |
metformin hydrochloride alone |
AMP activated protein kinase stimulator |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Minnesota |
|
US |
2020-09-30 |
2021-09-30 |
MET-Covid, METFORMIN, NCT04510194 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
12 Months |
1522 |
Carolyn Bramante, MD |
2020-08-26 |
| National Survey for Mental Health and Well-being (NSMHW) Project Lingap sa Bawat Pamilyang Pilipino |
Coronavirus disease 19 infection |
|
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of the Philippines |
|
Philippines |
2020-07-05 |
2021-05-03 |
PHRR200804-002806 |
Phase Not Applicable |
Status not specified |
1 |
9 Months |
|
Cynthia Ramos-Leynes, Erniel Barrios, Evelyn G. Gapuz, John Eustaquio, Maria Lourdes Rosanna E de Guzman, Marilyn Crisostomo, Marissa Pascual, Tomas D. Bautista |
2020-08-18 |
| Teleophthalmology in a developing country in light of the COVID-19 Pandemic |
Coronavirus disease 19 infection |
|
|
|
Philippine General Hospital |
|
Philippines |
2020-07-29 |
|
PHRR200804-002800 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
|
Corrina Azarcon, Darby E. Santiago, Felice Katrina T. Ranche |
2020-08-17 |
| Safety and efficacy of intranasal delivery of BromAc (Bromelain and Acetylcysteine) in swab positive SARS-CoV-2 COVID-19 patients |
Coronavirus disease 19 infection |
BromAc alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Mucpharm Pty Ltd |
|
Australia |
2020-08-17 |
2020-09-30 |
ACTRN12620000788976p, U1111-1256-2985 |
Phase 1 Clinical |
Not yet recruiting |
1 |
1 Month |
30 |
Miss Sarah Valle, Prof David Morris |
2020-08-31 |
| Effect of a Brief Problem Management Intervention on Anxiety and Depression Arising from COVID-19-Related Financial Stress |
Anxiety disorder, Coronavirus disease 19 infection, Depression |
Enhanced Treatment as Usual alone, Problem Management Plus alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
UNSW Sydney |
National Health and Medical Research Council |
Australia |
2020-09-30 |
2021-01-29 |
ACTRN12620000787987 |
Phase Not Applicable |
Not yet recruiting |
1 |
4 Months |
206 |
Prof Richard Bryant |
2020-08-31 |
| Psychological health condition and effect of psychological couseling of infertile couples receiving ART during novel coronavirus pneumonia (COVID-19) pandemic |
Coronavirus disease 19 infection, Infertility, Viral pneumonia |
Psychological counseling alone |
|
|
International Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University |
|
China |
2020-08-17 |
|
ChiCTR2000035362 |
Phase 0 Clinical |
Not yet recruiting |
1 |
|
300 |
Li Jin, Luting Chen |
2020-08-17 |
| COVID-19 Health and wellbeing Trial in Bangladesh |
Acute stress disorder, Coronavirus disease 19 infection, Depression |
telecounseling alone |
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Khulna University, Monash University |
Global Development & Research Initiative Foundation (GDRI) |
Bangladesh |
2020-05-31 |
2020-06-15 |
ACTRN12620000795998, U1111-1254-7316 |
Phase Not Applicable |
No longer recruiting |
1 |
|
2402 |
Prof Asadul Islam |
2020-08-31 |
| Evaluation of muscle weakness, function and quality of life after Intensive Care Unit discharge in survivors of COVID-19 |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital do Servidor Publico Estadual |
|
Brazil |
2020-05-20 |
|
31759020.4.0000.5463, 4,032,543, RBR-564y4n, U1111-1254-0762 |
Phase Not Applicable |
Recruiting |
1 |
|
90 |
Lucas Simões Arrebola |
2020-08-20 |
| Medical care by video calls in Parkinson's disease patients at Hospital Universitário Walter Cantidio- UFC |
Coronavirus disease 19 infection, Parkinsons disease |
telehealth monitoring alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Federal University of Ceara |
Walter Cantídio University Hospital |
Brazil |
2020-05-12 |
|
1111-1253-7783, 31232720.2.0000.5045, 4,009,005, RBR-6pq44p |
Phase Not Applicable |
Recruiting |
1 |
|
100 |
Danielle Pessoa Lima, Pedro Braga Neto |
2020-08-26 |
| Testing of BCG vaccine against COVID-19 |
Coronavirus disease 19 infection |
BCG vaccine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universidade Federal de Goias |
Lebanese National Council for Scientific Research |
Brazil |
2020-08-05 |
|
31783720.0.0000.5078, 4,158,225, RBR-4kjqtg, U1111-1256-3892 |
Phase 2 Clinical |
Recruiting |
1 |
|
400 |
Ana Paula Junqueira Kipnis |
2020-08-31 |
| A phase III trial was to assess COVID-19 vaccinen for the treatment of COVID-19 patients |
Coronavirus disease 19 infection |
COVID-19 vaccine (inactivated, Vero cells/intramuscular), Wuhan Institute of Biological Products/Wuhan Institute of Virology, CAS alone |
|
|
Sinopharm China National Biotech Institute Co Ltd |
|
Bahrain |
|
|
|
Phase 3 Clinical |
Recruiting |
1 |
|
6000 |
|
2020-08-21 |
| Coronavirus (COVID-19) antibody response in healthcare staff: What proportion of healthcare staff have COVID-19 antibodies? How long do the antibodies last? Do the antibodies protect against recurring infection? |
Coronavirus disease 19 infection |
antibody testing alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Abbott Rapid Diagnostics Jena GmbH |
|
UK |
2020-04-22 |
2021-03-31 |
CLDG-0504, IRAS 284671, CPMS 46155, ISRCTN15634328 |
Phase Not Applicable |
Recruiting |
1 |
11 Months |
2000 |
Prof Patrick T. Kennedy |
2020-08-17 |
| Treatment of severe COVID-19 with angiotensin-(1-7) |
Coronavirus disease 19 infection |
angiotensin- (1-7) alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Angitec, Universidade Federal de Minas Gerais |
FAPEMIG |
Brazil |
2020-08-05 |
|
4.155.266, CAAE: 34080720.0.1001.5149, RBR-35734p, U1111-1255-7167 |
Phase 1/Phase 2 Clinical |
Recruiting |
1 |
|
130 |
Ana Luiza Martins Valle, Robson AS Santos |
2020-08-18 |
| Software to evaluate clinical, epidemiological data and chest computed tomography to predict which patients with COVID-19 will develop a severe form of the disease |
Coronavirus disease 19 infection |
computed tomography alone |
|
|
Diagnosticos da America SA, Hospital Alemao Oswaldo Cruz |
|
Brazil |
2020-03-02 |
|
CAAE: 30548620.0.1001.0008, Número de parecer: 3.968.706, RBR-7dsxsv, U1111-1254-6271 |
Phase Not Applicable |
Recruiting |
1 |
|
500 |
Felipe Campos Kitamura, Flavia Paiva Proença Lobo Lopes |
2020-08-18 |
| FREEDOM COVID: FREEDOM COVID-19 Anticoagulation Strategy |
Coronavirus disease 19 infection |
apixaban alone |
Factor Xa antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Mount Sinai Medical Center |
|
US |
2020-09-30 |
2021-06-30 |
FREEDOM COVID, GCO 20-2115, NCT04512079 |
Phase 4 Clinical |
Not yet recruiting |
1 |
9 Months |
3600 |
Anu Lala, MD, Debra Fitzpatrick, MS, Valentin Fuster, MD, PhD, Valentin Fuster, MD,PhD |
2020-08-17 |
| A Study to Evaluate The Efficacy, Safety and Immunogenicity of Inactivated SARS-CoV-2 Vaccines (Vero Cell) in Healthy Population Aged >/= 18 Years Old |
Coronavirus disease 19 infection |
COVID-19 vaccine (inactivated, Vero cells/intramuscular), Beijing Biological Products Institute/National Institute for Viral Disease Control and Prevention of Chinese Center for Disease Control and Prevention alone, COVID-19 vaccine (inactivated, Vero cells/intramuscular), Wuhan Institute of Biological Products/Wuhan Institute of Virology, CAS alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
China National Biotec Group, Group 42 Holding Ltd, Sinopharm China National Biotech Institute Co Ltd |
Abu Dhabi Health Services Company PJSC (SEHA), Beijing Biological Products Institute Co Ltd, G42 Healthcare, Wuhan Institute of Biological Products Co Ltd |
United Arab Emirates, Bahrain |
2020-07-16 |
2021-09-16 |
CNBG2020003SQ, NCT04510207 |
Phase 3 Clinical |
Recruiting |
3 |
14 Months |
45000 |
H.E. Sheikh Abdullah bin Mohammed Al Hamed, Manaf M Alqahtani, Prof., Najiba Abdulrazzaq, Doctor, Nawal AI Kaabi, MD, Walid A Zaher, MD, MSc,PhD, Yunkai Yang, Prof. |
2020-08-21 |
| Scaling Mental Healthcare in COVID-19 With Voice Biomarkers |
Anxiety disorder, Coronavirus disease 19 infection, Depression |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kintsugi Mindful Wellness Inc |
|
|
2020-09-01 |
2021-06-30 |
COV-1, NCT04510519 |
Phase Not Applicable |
Not yet recruiting |
0 |
10 Months |
50 |
|
2020-08-17 |
| COVID-19 in Immunosuppressed Children |
Coronavirus disease 19 infection, Hematological neoplasm, Kidney transplantation, Liver transplantation |
|
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Instituto D'Or de Pesquisa |
Hospital Federal de Bonsucesso |
Brazil |
2020-06-30 |
2021-04-30 |
062-2020, NCT04511429 |
Phase Not Applicable |
Recruiting |
2 |
10 Months |
200 |
Antonio José L A da Cunha, MD, PhD, Arnaldo Prata-Barbosa, MD, PhD, Jaqueline LS Gouveia, MD, Thais L Cleto-Yamane, Thais L Cleto-Yamane, MD, MSc |
2020-08-17 |
| MentCovid19RMD: Mental Health Consequences of COVID19 Infection in the French RMD Cohort |
Autoimmune disease, Autoinflammatory disease, Coronavirus disease 19 infection, Inflammatory disease, Musculoskeletal disease |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Regional Universitaire de Lille |
FAI²R (Auto-immune and auto-inflammatory rare diseases French network) |
France |
2020-09-30 |
2021-02-28 |
2020-A02058-31, 2020_75, MentCovid19RMD, NCT04510467 |
Phase Not Applicable |
Not yet recruiting |
2 |
5 Months |
1313 |
Eric Hachulla, MD,PhD |
2020-08-18 |
| A clinical study to assess the effects of Meditation (Mindful Happiness) as an additional therapy in asymptomatic and mildly symptomatic covid-19 confirmed cases |
Coronavirus disease 19 infection |
Meditation (Mindful Happiness) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Sonalika Social development Society |
|
India |
2020-08-11 |
|
CTRI/2020/08/027032, TG/PRO/CLI/034 Version 1.0 dated 10 July 2020 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
40 |
Dr Bhageerathi Byrapura Lakshmegowda, Dr Vishwas Vijayadev, Meena Dalal |
2020-08-17 |
| COLHEART-19: Colchicine versus Current Standard of Care in Hospitalized Patients With COVID-19 and Cardiac Injury |
Coronavirus disease 19 infection, Heart injury |
Covid-19 standard of care alone, colchicine (oral, gout/familial Mediterranean fever), Takeda alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Miami Cardiac and Vascular Institute |
University of California Los Angeles |
US |
2020-09-01 |
2022-01-01 |
152247, COLHEART-19, NCT04510038 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
16 Months |
75 |
Raul E Herrera, MD, Sandra Chaparro, MD |
2020-08-17 |
| AI-COV-19: Artificial Intelligence-assisted Diagnosis and Prognostication in COVID-19 Using Electrocardiograms |
Coronavirus disease 19 infection |
CT scans alone, Chest x-ray imaging alone, ECGs alone, RTPCR assay alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Imperial College London |
Chelsea and Westminster Hospital, Imperial College Healthcare NHS trust, London North West Healthcare NHS Trust |
UK |
2020-05-26 |
2022-05-01 |
20HH5967, AI-COV-19, NCT04510441 |
Phase Not Applicable |
Recruiting |
4 |
23 Months |
2000 |
Abtehale Al-Hussaini, MRCP PhD, Emmanuel Ako, MRCP PhD, Fu Siong Ng, Jaymin Shah, MRCP PhD, Kiran Patel |
2020-08-17 |
| A clinical trial of CYC-065 and seliciclib as potential early treatments for the inflammatory response observed in patients with COVID-19 disease |
Coronavirus disease 19 infection, Inflammatory disease |
fadraciclib plus seliciclib |
Cyclin E inhibitor, Cyclin-dependent kinase-2 inhibitor, Cyclin-dependent kinase-5 inhibitor, Cyclin-dependent kinase-7 inhibitor, Cyclin-dependent kinase-9 inhibitor, MCL1 gene inhibitor |
|
Cyclacel Pharmaceuticals Inc |
University of Edinburgh |
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-08-14 |
| CanCovDia: Canakinumab in Patients With COVID-19 and Type 2 Diabetes |
Coronavirus disease 19 infection, Non-insulin dependent diabetes |
canakinumab alone |
Immunoglobulin G1 agonist, Interleukin-1 beta ligand inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Basel |
Novartis AG, Swiss National Science Foundation |
Switzerland |
2020-09-30 |
2023-09-30 |
2020-02008, ME20DONATH2, CanCovDia, NCT04510493 |
Phase 3 Clinical |
Not yet recruiting |
8 |
36 Months |
116 |
Alain Golay, MD, Prof., Beat Müller, MD, Prof., Christoph Henzen, MD, Prof., Christoph Stettler, MD, Prof., Felix Beuschlein, MD, Prof., François Jornayvaz, MD, PD, Jonathan Mudry, MD, Lukas Burget, MD, Manuel Battegay, MD, Prof., Marc Donath, MD, Prof., Markus Laimer, MD, Prof., Matthias Hepprich, MD, Michael Brändle, MD, Prof., Nelly Pittteloud, MD, Prof., Patrick Hunziker, MD, Prof., Peter Kopp, MD, Prof., Philipp Schütz, MD, Prof., Roger Lehmann, MD, Prof., Stefan Bilz, MD, PD, Stefan Fischli, MD |
2020-08-20 |
| FAMICOV: COVID-19: Epidemiological Study of the Spread of SARS-CoV-2 in the Household of a Person Who Has Had a COVID-19 Disease |
Coronavirus disease 19 infection |
COVID-19 IgG / IgM rapid test (manufactured by the firm AAZ) alone, COVID-PRESTO alone |
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre de Recherches et d'Etude sur la Pathologie Tropicale et le Sida |
|
France |
2020-07-12 |
2020-11-30 |
CREPATS 012, FAMICOV, NCT04511949 |
Phase Not Applicable |
Recruiting |
1 |
4 Months |
500 |
Christine Katlama, Yasmine Dudoit |
2020-08-18 |
| A phase II to assess safety, tolerability and pharmacokinetics (PK) of PLN-74809, as well as exploratory clinical outcome measures in patients hospitalized with severe and critical COVID-19 associated with acute respiratory distress syndrome (ARDS) |
Coronavirus disease 19 infection, Respiratory distress syndrome |
PLN-74809 alone |
Integrin alpha-V/beta-1 antagonist, Integrin alpha-V/beta-6 antagonist |
|
Pliant Therapeutics Inc |
|
US |
2020-12-31 |
|
|
Phase 2 Clinical |
Planned |
1 |
|
|
|
2020-08-14 |
| Effect of Prolectin-M, a Food Supplement, on SarsCoV2 Viral Copy Numbers: A Proof of Concept, Randomized, Open-Label, Controlled Trial (Prolectin) |
Coronavirus disease 19 infection |
Prolectin (Pharmalectin - M) alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Composite Interceptive Med-Science Laboratories Pvt Ltd |
Pharmalectin Inc |
India |
2020-09-01 |
2020-09-30 |
CIMED - 002- 2020, NCT04512027 |
Phase Not Applicable |
Not yet recruiting |
1 |
1 Month |
10 |
|
2020-08-17 |
| STAR-COVID: Telmisartan in Respiratory Failure Due to COVID-19 |
Coronavirus disease 19 infection, Hypoxia, Respiratory failure, Tachypnea |
standard care alone, telmisartan alone |
Angiotensin II receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Regional de Alta Especialidad de Zumpango |
Instituto Politecnico Nacional |
Mexico |
2020-08-31 |
2021-04-30 |
CI/HRAEZ2020/05, NCT04510662, STAR-COVID |
Phase 2 Clinical |
Recruiting |
1 |
8 Months |
60 |
Abraham Edgar Gracia-Ramos, MD MSc, Maria Jose Pecero Hidalgo, MD, Maria Jose Pecero-Hidalgo, MD |
2020-08-17 |
| PSY-CO-ICU: Psychological Impact of COVID-19 Outbreak on Caregivers |
Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire de Nimes |
|
France |
2020-09-30 |
2021-09-30 |
LOCAL/2020/JYL-03, NCT04511780, PSY-CO-ICU |
Phase Not Applicable |
Not yet recruiting |
48 |
12 Months |
5000 |
Alexandre OUATTARA, Antoine ROQUILLY, Audrey DE JONG, Aurélie GOUEL, Belaid BOUHEMAD, Benoit PLAUD, Benoit VEBER, Bernard ALLAOUCHICHE, Bernard CHOLLEY, Bérangère VIVET, Claire DAHYOT FIZELIER, Claude ECOFFEY, Corentin LACROIX, Emmanuel FUTIER, Emmanuel SAMAIN, Eric PIKNIS, Etienne GAYAT, Francis REMERAND, Frédéric AUBRUN, Gael PITON, Guillaume BESCH, Guylaine LABRO, Gérald CHANQUES, Géralde CHANQUES, Gérard AUDIBERT, Hervé DUPONT, ICHAI Carole, Jacques ALBANESE, Jacques DURANTEAU, Jean Etienne BAZIN, Jean François PAYEN, Jean Luc FELLAHI, Jean Michel CONSTANTIN, Jean Yves LEFRANT, Julien POTTECHER, Jérôme MOREL, Karim ASEHNOUNE, Karim LAKHAL, Lionel VELLY, Mar Olivier FISCHER, Marc LAFFON, Marc LEONE, Marie reine LOSSER, Matthieu BIAIS, Matthieu LE DORZE, Nathalie NATHAN-DENIZOT, Nathan FERRAND, Nicolas BRUDER, Nicolas MONGARDON, Olivier BARBOT, Olivier FOURCADE, Olivier HUET, Olivier JOANNES BOYAU, Olivier LANGERON, Philippe GUERCI, Philippe MONTRAVERS, Philippe SEGUIN, Pierre François PERRIGAULT, Rémy BELLIER, Samir JABER, Sigismond LASOCKI, Sébastien PILI-FLOURY, Thomas KERFORNE, Thomas RIMMELE, Xavier CAPDEVILA, Yazine MAHJOUB, marc GARNIER |
2020-08-16 |
| C-MORE: Capturing Multi-organ Effects of COVID-19 |
Brain injury, Coronavirus disease 19 infection, Heart injury, Liver injury, Lung injury, Renal injury, Respiratory distress syndrome, Viral pneumonia |
6 min walk test alone, blood test alone, cardiopulmonary exercise test alone, computed tomography alone, magnetic resonance imaging alone, spirometry alone, transthoracic echocardiography alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Oxford |
|
UK |
2020-05-13 |
2023-05-01 |
282608, C-MORE, NCT04510025 |
Phase Not Applicable |
Recruiting |
1 |
35 Months |
616 |
Betty Raman, MBBS, DPhil, FRAC, Betty Raman, MBBS, DPhil, FRACP, Betty Raman, MBBS, FRACP, DPhil, Mark Cassar, MBBS, Stefan Neubauer, MD, FMedSCi |
2020-08-19 |
| A clinical study to assess AR-701 in the treatment of patients with COVID-19 |
Coronavirus disease 19 infection |
AR-701 alone |
COVID19 Spike glycoprotein inhibitor |
|
Aridis Pharmaceuticals Inc |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-08-14 |
| CT Abnormalities Evocative of Lung Infection Are Associated With Lower 18F-FDG Uptake in Confirmed COVID-19 Patients |
Coronavirus disease 19 infection, Lung infection |
18F-FDG alone, Vereos digital hybrid system (Philips) alone, computed tomography alone, positron emission tomography alone, viral testing alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Central Hospital, Nancy, France |
|
France |
2020-03-15 |
2020-07-30 |
2020PI153, NCT04512118 |
Phase Not Applicable |
Completed |
1 |
4 Months |
22 |
Antoine VERGER |
2020-08-18 |
| Dysphagia Management During COVID-19 Pandemic |
Coronavirus disease 19 infection, Dysphagia |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Hacettepe University |
|
Turkey |
2020-08-20 |
2020-11-30 |
DYSPHAGIA DURING COVID-19, NCT04509752 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
50 |
NUMAN DEMİR, SELEN SEREL ARSLAN |
2020-08-17 |
| Parental Attitude Toward Children Dental Treatment During COVID-19 Pandemic |
Coronavirus disease 19 infection, Tooth disease |
|
|
|
Cairo University |
|
Egypt |
2020-06-15 |
2020-06-25 |
COVID -19 AND DENTAL VISIT, NCT04512300 |
Phase Not Applicable |
Completed |
1 |
|
267 |
Yasmin Mohamed |
2020-08-16 |
| Phase I/II Trial of Povidone-iodine (PVP-I) Nasal Swab For Preventing COVID-19 Spread in Healthy Subjects |
Coronavirus disease 19 infection |
povidone-iodine alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Brigham & Women's Hospital |
3M Co |
US |
2020-08-31 |
2021-04-30 |
2020P002323, NCT04510402 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
8 Months |
50 |
Mark D Hornstein, MD, Raymond M Anchan, MD, PhD, Raymond Manohar Anchan, M.D.,Ph.D. |
2020-08-17 |
| Multicenter, randomized, double-blind, placebo-controlled, parallel group study evaluating the efficacy, reactogenicity and safety of the Ad5-nCoV recombinant vaccine against novel coronavirus infection in adult volunteers |
Coronavirus disease 19 infection |
Ad5-nCoV alone |
COVID19 Spike glycoprotein modulator |
Healthy volunteers accepted |
CanSino Biologics Inc, NPO Petrovax Pharm LLC |
|
Russian Federation, Chile, Brazil, Saudi Arabia |
2020-08-14 |
2021-07-31 |
Prometheus_Rus |
Phase 3 Clinical |
Not yet recruiting |
11 |
11 Months |
5000 |
|
2020-08-24 |
| CHARTER-Irl: Nebulized Heparin to Reduce COVID-19 Induced Acute Lung Injury |
Acute lung injury, Coronavirus disease 19 infection |
nebulized unfractionated heparin alone, standard care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University College Galway |
|
Ireland |
2020-09-30 |
2022-01-31 |
CHARTER-Irl, NCT04511923, NUIG-2020-003 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
16 Months |
40 |
David Cosgrave, John Laffey |
2020-08-16 |
| Transparent Elastomeric Respirator for Aerosol-based Protection |
Coronavirus disease 19 infection |
reusable elastomeric respirator with dual N95 filter alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Brigham & Women's Hospital |
Massachusetts General Hospital, Memorial Sloan-Kettering Cancer Center |
US |
2020-07-25 |
2020-12-31 |
2020P000852, NCT04511390 |
Phase Not Applicable |
Recruiting |
3 |
5 Months |
100 |
C. Giovanni Traverso, Giovanni Traverso, MB, BChir, PhD, Manish Gala, MD, Paul Zel |
2020-08-17 |
| LOSVID: Losmapimod Safety and Efficacy in COVID-19 |
Coronavirus disease 19 infection, Inflammatory disease, Respiratory failure |
losmapimod alone, standard of care alone |
Double homeobox protein 4 inhibitor, p38 MAP kinase alpha inhibitor, p38 MAP kinase beta inhibitor, p38 MAP kinase inhibitor |
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fulcrum Therapeutics Inc |
|
Brazil, Mexico, US |
2020-08-31 |
2020-11-30 |
FIS-001-2020, LOSVID, NCT04511819 |
Phase 3 Clinical |
Recruiting |
10 |
3 Months |
410 |
Call Center, Daniela Pereira Mendes, David Rubio, MD, Diego Cadavid, MD, Folusakin Ayoade, MD, Iram Abbasi, Jose' Flores, MD, Karel Calero, MD, Natiana Nalin Vizioli, Rayo Morfin, MD, Rebecca Zash, MD, Rosie Magallon, Veronica Martin |
2020-08-19 |
| Feasibility, of Tele-rehabilitation Following COVID-19 |
Coronavirus disease 19 infection, Dyspnea |
Tele-pulmonary rehabilitation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hull University Teaching Hospitals NHS Trust |
|
UK |
2020-08-12 |
2022-01-20 |
285205, NCT04511962 |
Phase 3 Clinical |
Not yet recruiting |
1 |
17 Months |
40 |
Angela Green, PhD, Caroline e Wright, BSc, Michael Crooks, MRCP, Michael Crooks, MRCP/MD, Michael f Crooks, MRCP |
2020-08-16 |
| RESCUE: A Study to Evaluate the Safety and Efficacy of Razuprotafib, a Novel Tie 2 Activator, in Hospitalized Subjects With Moderate to Severe Coronavirus Disease 2019 (COVID-19) |
Coronavirus disease 19 infection |
razuprotafib alone |
Protein tyrosine phosphatase beta inhibitor, Tek tyrosine kinase receptor stimulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Aerpio Therapeutics Inc |
Medical Technology Enterprise Consortium |
|
2020-09-30 |
2021-02-28 |
AKB-9778-CI-6001, NCT04511650, RESCUE |
Phase 2 Clinical |
Not yet recruiting |
0 |
5 Months |
180 |
Ashley Best, PhD |
2020-08-18 |
| Bicalutamide to Block TMPRSS2 in Males With COVID-19 Infection |
Coronavirus disease 19 infection |
bicalutamide alone |
Androgen receptor antagonist |
Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Florida |
|
US |
2020-09-30 |
2022-09-30 |
IRB202001669-A, NCT04509999, OCR38162 |
Phase 3 Clinical |
Not yet recruiting |
1 |
24 Months |
100 |
Elizabeth Piantadosi, Frederic Kaye, MD |
2020-08-24 |
| Evaluation of the effectiveness of hydroxychloroquine and clarithromycin in dyspnea and cough caused by COVID-19 in recovery phase |
Coronavirus disease 19 infection, Cough, Dyspnea |
clarithromycin (Tehran shimi company) alone, hydroxychloroquine (Rooz daroo company) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Iran University of Medical Sciences |
|
Iran |
2020-08-22 |
|
IR.IUMS.FMD.REC.1399.244, IRCT20200718048129N1 |
Phase 3 Clinical |
Recruiting |
1 |
|
45 |
Dr Sima Bahrami, Dr. Seyed Abbas Motavlian, Sima Bahrami |
2020-08-24 |
| Helmet versus Face Mask in Patients With Acute Respiratory Distress Syndrome |
Coronavirus disease 19 infection, Respiratory distress syndrome |
non invasive ventilation via helmet alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hamad Medical Corp |
|
Qatar |
2020-08-31 |
2021-08-31 |
MRC-01-20-616, NCT04507802 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
60 |
Abdulqadir J Nashwan, MSc, Abdulqadir J. Nashwan, MSc, Ahmed A Soliman, BSc, Ahmed S Mohamed, BSc, Ahmed S. Mohamed, BSc, Dore C Ananthegowda, MD, Hani S Elzeer, MD, Karimulla S Shaik, MD, Mohamad Y Khatib, MD, Mohamed Z Peediyakkal, MD, Moustafa S Elshafei, MD, Muhsen A Shahen, MD, Nevin Kannappilly, MD, Wael I Abdaljawad, MD |
2020-08-17 |
| Evaluating the effectiveness of intravenous ozonized saline in COVID-19 disease |
Coronavirus disease 19 infection |
Medozon device alone, Variable regimens including IFN beta-1a , IFN beta-1b , atazanavir + ritonavir , chloroquine phosphate , dexamethasone , enoxaparin sodium , heparin , hydroxychloroquine , lopinavir + ritonavir , ozonized saline |
HIV protease inhibitor, Low molecular weight heparin |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Ahvaz University of Medical Sciences |
|
Iran |
2020-08-22 |
|
IR.AJUMS.REC.1399.363, IRCT20200730048253N1 |
Phase 3 Clinical |
Recruiting |
1 |
|
60 |
Dr. mohammad Badavi, Dr.Najme dareini, Najme dareini, Shokrollah Salmanzadeh Ramhormozi |
2020-08-24 |
| ONCOVID-21: Evaluation of a ddPCR Technology for the SARS-CoV-2 Detection in Symptomatic Patients With Suspicion of COVID-19 |
Coronavirus disease 19 infection |
Bio-Rad SARS-CoV-2 ddPCR Test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Leon Berard |
|
France |
2020-09-30 |
2021-03-31 |
NCT04510454, ONCOVID-21, ONCOVID-21 - ET20-118 |
Phase Not Applicable |
Not yet recruiting |
1 |
6 Months |
200 |
Bénédicte MASTROIANNI, MD, Ellen BLANC |
2020-08-19 |
| Profile of hospitalized patients with Covid-19 and repercussions of physiotherapy |
Coronavirus disease 19 infection |
physiotherapy alone |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo |
|
Brazil |
2020-06-18 |
|
33351020.2.0000.0068, 4.091.795, 4.172.084, RBR-2f9k8p, U1111-1255-6608 |
Phase Not Applicable |
Recruiting |
1 |
|
2000 |
Clarice Tanaka |
2020-08-14 |
| A survey to analyze the understanding about the use of face mask among the general public during COVID 19 |
Coronavirus disease 19 infection |
face mask alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Kasturba Medical College and Hospital |
|
India |
2020-08-20 |
|
CTRI/2020/08/027046 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
697 |
Dr Ranita Ghosh Dastidar, Dr Vaishali K |
2020-08-24 |
| Nursing students perception of out of the classroom learning during the period of COVID-19 |
Coronavirus disease 19 infection |
|
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Manipal College of Nursing |
|
India |
2020-08-31 |
|
CTRI/2020/08/027047 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
380 |
Linu Sara George, Prima Jenevive Jyothi DSouza |
2020-08-14 |
| Yoga for Police personnel |
Coronavirus disease 19 infection |
Pranayama and Yoga Nidra alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Sri Devaraj Urs Academy of Higher Education and Research |
|
India |
2020-08-17 |
|
CTRI/2020/08/027048 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
60 |
Dr Patil NJ |
2020-08-14 |
| Effect of hemoperfusion on short-term outcome of critical ill COVID-19 |
Acute stress disorder, Coronavirus disease 19 infection, Delirium |
ABCDE protocol alone, CytoSorb filter alone, anticoagulant therapy alone, antiviral therapy alone, blood sugar management alone, complementary medication therapy alone, corticosteroid therapy alone, face mask alone, hemoperfusion therapy alone, heparin alone, low tidal volume ventilation alone, non-invasive mechanical ventilation alone, proton pump inhibitor therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Tabriz University of Medical Sciences |
|
Iran |
2020-08-22 |
|
IR.TBZMED.REC.1399.493, IRCT20091012002582N22 |
Phase 3 Clinical |
Recruiting |
1 |
|
160 |
Ata Mahmoodpoor, Dr. khosro Adibkia, Mojtaba Mohammadzadeh |
2020-08-24 |
| Study of families who travelled from another place and had COVID-19 |
Coronavirus disease 19 infection |
|
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Dr TMA Pai Hospital |
|
India |
2020-08-20 |
|
CTRI/2020/08/027049 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
19 |
Shashikiran Umakanth |
2020-08-17 |
| PPE Study: Assessment of PPE usage pattern and the associated Surgeon Discomfort and Fatigue Study |
Coronavirus disease 19 infection, Fatigue |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Tata Memorial Centre |
|
India |
2020-08-20 |
|
CTRI/2020/08/027050, PPE Study |
Phase Not Applicable |
Not yet recruiting |
1 |
|
500 |
DrShivakumar Thiagarajan |
2020-08-14 |
| Survey of challenges faced by pain and palliative physicians working in cancer set up during corona virus disease time |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
All India Institute of Medical Sciences |
|
India |
2020-08-10 |
|
CTRI/2020/08/027051 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
200 |
Dr Seema Mishra |
2020-08-14 |
| Evaluation of the effect of curcumin in improving patients with covid -19 |
Coronavirus disease 19 infection |
curcumin-piperine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Bandare-abbas University of Medical Sciences |
|
Iran |
2020-08-05 |
|
IR.HUMS.REC.1399.187, IRCT20200514047445N1 |
Phase 3 Clinical |
No longer recruiting |
1 |
|
60 |
Majid Teremmahi Ardestani, Timur Agha Molai |
2020-08-24 |
| A trial to evaluate OraCOV for the prevention of COVID-19 |
Coronavirus disease 19 infection |
OraCOV alone |
|
|
covidX |
|
Germany |
|
|
|
Phase Not Applicable |
Planned |
1 |
|
|
|
2020-08-18 |
| GlobalSurg-CovidSurg Week |
Coronavirus disease 19 infection |
surgery alone |
|
|
The University of Birmingham |
Association of Coloproctology of Great Britain and Ireland, Bowel Disease Research Foundation of ACPGBI, Bowel and Cancer Research, British Association of Surgical Oncology: Breast Group, British Gynaecological Cancer Society, European Society of Coloproctology, NIHR Academy, National Institute for Health Research (NIHR), Sarcoma UK, Vascular Society for Great Britain and Ireland, Yorkshire Cancer Research |
UK |
2020-10-01 |
2020-12-01 |
GS-CSWEEK.20200713, NCT04509986 |
Phase Not Applicable |
Not yet recruiting |
1 |
2 Months |
1000 |
Aneel Bhangu, PhD, Dmitri Nepogodiev, Master |
2020-08-18 |
| Virtual Teaching Kitchen |
Coronavirus disease 19 infection, Metabolic syndrome X |
Virtual Nutritional Education alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Boston University |
|
US |
2020-09-30 |
2021-06-30 |
H-39597, NCT04509206 |
Phase Not Applicable |
Not yet recruiting |
1 |
9 Months |
25 |
Iniya Rajendran, Naomi M Hamburg, MD |
2020-08-19 |
| KAND-567 Versus Placebo in Subjects Hospitalized with COVID-19. A Phase II, Randomized, two-Arm, Parallel-Group, Double-blind Study to Evaluate Efficacy, Safety, Tolerability, and Pharmacokinetics |
Coronavirus disease 19 infection |
KAND-567 alone, best standard treatment alone |
CX3CR1 chemokine antagonist, Fractalkine ligand inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kancera AB |
Capio S:t Görans Hospital, Scandinavian CRO, Scandinavian Development Services AB, Science For Life Laboratory |
Sweden |
2020-07-02 |
|
2020-002322-85, KAN0006 |
Phase 2 Clinical |
Recruiting |
1 |
|
40 |
Anna Runeson |
2020-08-14 |
| Effect of erythropoietin on COVID-19 |
Coronavirus disease 19 infection, Hypoxia, Lung disease, Lymphocytopenia, Tachypnea |
Variable regimens including atazanavir , atazanavir + ritonavir , chloroquine phosphate , enoxaparin sodium , epoetin alfa (Procrit/Eprex), Johnson & Johnson , hydroxychloroquine sulfate , lopinavir + ritonavir |
Erythropoietin ligand, HIV GAG POL polyprotein inhibitor, HIV GAG protein inhibitor, HIV protease inhibitor, HIV-1 protease inhibitor, Low molecular weight heparin |
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Bandare-abbas University of Medical Sciences |
|
Iran |
2020-06-21 |
|
IR.HUMS.REC.1399.165, IRCT20200509047364N1 |
Phase 2 Clinical |
Recruiting |
1 |
|
20 |
Dariush Hooshyar, Dr. Mehdi Hassaniazad, Dr. Mitra Kazemijahromi, Dr. Teamur Aghamolaei |
2020-08-18 |
| Evaluation of the effect of shallomin on the treatment and improvement of symptoms in patients with Covid 19 |
Coronavirus disease 19 infection, Respiratory disease |
approved COVID19 protocol treatment alone, shallomin (Sadra Noor Biotechnology Pharmaceutical Company) alone |
|
|
Dezful University of Medical Sciences |
|
Iran |
2020-08-10 |
|
IR.DUMS.REC.1399.014, IRCT20200725048199N1 |
Phase 2 Clinical |
Recruiting |
1 |
|
146 |
Mahnaz Nosratabadi, Maysam Mardsoltani, mahnaz nosratabadi |
2020-08-18 |
| ARBS CORONA I: Host-Response Mediators in Coronavirus (COVID-19) Infection |
Coronavirus disease 19 infection |
angiotensin II type 1 receptor blocker therapy alone, angiotensin-converting enzyme inhibitor therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of British Columbia |
British Columbia Centre for Disease Control, Canadian Institutes of Health Research, McGill University Health Center, Peking Union Medical College Hospital, Research Institute of the McGill University Health Centre, University of Alberta, University of Calgary, University of Ottawa, University of Pennsylvania, University of Toronto, University of Victoria, Wuhan University |
Canada |
2020-03-17 |
2022-06-30 |
ARBS CORONA I, H20-00600, NCT04510623 |
Phase Not Applicable |
Recruiting |
15 |
27 Months |
500 |
Allison McGeer, MD, Ari Joffe, MD, Brent Winston, MD, David Maslove, MD, David Sweet, MD, Francois Lamontagne, MD, Gregory Haljan, MD, James A Russell, MD, Jim Russell, John Marshall, MD, Lynda Lazosky, Matthew Cheng, MD, Nataly Farshait, Oleksa Rewa, MD, Puneet Mann, MSc, Robert Fowler, MD, Todd Lee, MD |
2020-08-14 |
| Canine COVID-19 Detection |
Coronavirus disease 19 infection |
traditional sniffer dog medical-detection alone |
|
Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Arthropod Control Product Test Center (ARCTEC) |
Cardiff University, Medical Detection Dogs, University of Durham |
UK |
2020-07-02 |
2020-10-31 |
LSH1285, NCT04509713 |
Phase 1 Clinical |
Recruiting |
1 |
3 Months |
16250 |
James Logan, James Logan, PHD |
2020-08-14 |
| A phase III clinical trial of Brexanolone in patients with advanced COVID-19 related acute respiratory distress syndrome (ARDS) |
Coronavirus disease 19 infection, Respiratory distress syndrome |
brexanolone alone |
GABA A receptor modulator |
|
SAGE Therapeutics Inc |
|
|
2020-12-31 |
|
|
Phase 3 Clinical |
Planned |
0 |
|
|
|
2020-08-13 |
| COVIDSTEROID2: Higher Versus Lower Doses of Dexamethasone for COVID-19 and Severe Hypoxia |
Coronavirus disease 19 infection, Hypoxia |
betamethasone alone, dexamethasone (Dexavit) alone, standard care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Scandinavian Critical Care Trials Group |
Aalborg Universitetshospital, Aarhus University Hospital, Centre for Research in Intensive Care (CRIC), Copenhagen Trial Unit, Rigshospitalet, Denmark, The George Institute for International Health |
Denmark, Switzerland, India, Sweden |
2020-08-17 |
2022-02-17 |
2020-003363-25, 2020-07-16, COVIDSTEROID2, H-20051056, NCT04509973, RH-ITA-009 |
Phase 3 Clinical |
Not yet recruiting |
51 |
18 Months |
1000 |
Amit Shobhavat, Anders Møller, Anders Perner, MD PhD, Anders Perner, MD, PhD, Professor, Andreas Wiklund, Anna Nilsson, Anne Sofie Andreasen, Bharath KT Vijayaraghavan, Binila Chacko, Buster Mannheimer, Carl-Johan Treutiger, Farhad Kapadia, Fredrik Schiöler, Fredrik Sjövall, Iben S Darfelt, J V Divatia, Jacob Hollenberg, Jonathan Oras, Kapil Boraoke, Kedar Toraskar, Magnus Gisslen, Magnus Hedenstierna, Margit Smitt, MD, Marie Warrer B Petersen, MD, Marie Warrer Petersen, MD, Michelle Chew, Neeta B Nayak, Olof Wall, Omender Singh, Pontus Naucler, Pravin Amin, Rajesh Chawla, Saif M Khan, Sanjith Saseedharan, Sara Tehrani, Syed M Ahmed, Thomas Mohr, Urvi Shukla, Vibeke RL Jørgensen, MD, PhD, Zubair U Mohamed, Åke Norberg |
2020-08-14 |
| Ivermectin Nasal Spray for COVID-19 Patients |
Coronavirus disease 19 infection |
ivermectin alone, standard care alone |
Chloride channel modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Tanta University |
|
Egypt |
2020-09-30 |
2020-12-31 |
IVRINH, NCT04510233 |
Phase 2 Clinical |
Not yet recruiting |
1 |
3 Months |
60 |
Kamal Okasha, PhD, Nahla El-Ashmawy, PhD |
2020-08-14 |
| Characterizing the Immune Response and Neuronal Damage in COVID-19 |
Coronavirus disease 19 infection, Inflammatory disease, Nerve injury |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Inselspital, Berne |
University of Bern |
Switzerland |
2020-03-05 |
2021-03-05 |
NCOV19, NCT04510012 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
150 |
Cédric Hirzel, MD, Denis Grandgirard, PhD, Franziska Suter, PhD, Jörg C Schefold, MD, Leib L Stephen, MD, Ronald Dijkman, PhD, Thibaud Spinetti, PhD |
2020-08-14 |
| COVID SAFE: COVID-19 SAFE Enrollment |
Coronavirus disease 19 infection |
Opt-in Recruitment Email alone, Opt-out Recruitment Email alone, saliva-based viral testing alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Pennsylvania |
|
US |
2020-08-31 |
2020-10-31 |
843565, COVID SAFE, NCT04506268 |
Phase Not Applicable |
Not yet recruiting |
1 |
2 Months |
1200 |
Chalanda N Evans, BS, Mitesh S Patel, MD |
2020-08-18 |
| RAAS-COVID: The McGill RAAS-COVID-19 Trial |
Coronavirus disease 19 infection, Viral pneumonia |
anti-hypertensive medication alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Research Institute of the McGill University Health Centre |
McGill University Health Center, Sir Mortimer B Davis Jewish General Hospital, Université De Lorraine |
Canada |
2020-09-01 |
2021-09-01 |
MP-37-2021-6614, NCT04508985, RAAS-COVID |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
40 |
Abhinav Sharma, MD, Julie Lebel, PM |
2020-08-21 |
| Technology-assisted Index on Improving Hand Hygiene of Registered Nurses |
Coronavirus disease 19 infection |
3M Clean-Trace Surface ATP test alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Taiwan University Hospital |
|
Taiwan |
2020-08-31 |
2022-05-31 |
202006019RINB, NCT04508114 |
Phase Not Applicable |
Not yet recruiting |
1 |
21 Months |
120 |
Man-Rong Hsu, BSN, Wei-Wen Wu, PhD |
2020-08-13 |
| CoviDep: Treatment of Depressive Symptoms in Older Individuals in Isolation During Covid-19 |
Coronavirus disease 19 infection, Depression |
Brief Behavioral Activation with Mental Imagery alone |
|
Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Uppsala University |
Vastmanland County Council (Landstinget) |
Sweden |
2020-08-17 |
2021-07-31 |
2020-02079, CoviDep, NCT04508868 |
Phase Not Applicable |
Recruiting |
1 |
11 Months |
154 |
Johnny Pellas, MSc, Mattias Damberg, MD, PhD |
2020-08-20 |
| COVID-19 GDI: COVID-19 Germ Defence: a website to improve infection control during the COVID-19 pandemic |
Coronavirus disease 19 infection, Influenza virus infection, Respiratory tract infection |
COVID-19 Germ Defence website alone, digital behavioral change intervention alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Bristol |
NIHR Health Protection Research Unit (HPRU) in Behavioural Science and Evaluation, National Institute for Health Research, Applied Research Collaboration West (NIHR ARC West), United Kingdom Research & Innovation |
UK |
2020-03-30 |
2021-04-30 |
COVID-19 GDI, CPMS 46740, IRAS 287978, ISRCTN14602359, UKRI (MRC) MC_PC_19068, UOB 2020-3213 |
Phase Not Applicable |
Not yet recruiting |
15 |
13 Months |
6822 |
Dr Jeremy Horwood, Dr Melanie Chalder |
2020-08-13 |
| OMA-COVID-19: Effect of the anti-inflammatory test drug anakinra in patients with coronavirus (COVID-19) requiring oxygen support |
Coronavirus disease 19 infection, Inflammatory disease, Respiratory distress syndrome, Viral pneumonia |
anakinra alone |
Type I IL-1 receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sultan Qaboos University |
|
Oman |
2020-05-25 |
2020-08-15 |
ISRCTN74727214, OMA-COVID-19 |
Phase 2 Clinical |
Completed |
2 |
2 Months |
75 |
Dr Balkhair |
2020-08-18 |
| Japan COVID-19 Study of the psychosocial impacts of the postponement/cancellation of reproductive medicine |
Acute stress disorder, Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Dokkyo Medical University, Saitama Medical Center, Japan |
Japan Society for Reproductive Psychology |
Japan |
2020-08-17 |
|
UMIN000041387 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1100 |
Kouhei Sugimoto, Tomoe Koizumi |
2020-08-14 |
| COVER: Randomized, Double-blind, Multi Centre Phase II, Dose Finding Clinical Trial on Ivermectin for the early Treatment of COVID-19 Studio clinico randomizzato, in doppio cieco, multicentrico, di fase II, per l'individuazione del dosaggio di impiego dell'Ivermectina per il trattamento precoce del COVID-19 |
Coronavirus disease 19 infection |
ivermectin alone |
Chloride channel modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ospedale Sacro Cuore don Calabria |
|
Italy |
2020-06-12 |
|
2020-002283-32, 2020-34, COVER |
Phase 2 Clinical |
Recruiting |
1 |
|
122 |
Unità per la Ricerca Clinica |
2020-08-15 |
| Camphora in COVID: A clinical study to evaluate efficacy and safety of Camphora tablets in Covid positive patients |
Coronavirus disease 19 infection |
Camphora alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
TNMC and BYL Nair Hospital |
|
India |
2020-08-17 |
|
CTRI/2020/08/027045, Camphora in COVID |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
300 |
Dr Ashish Agarwal, Dr Renuka Munshi |
2020-08-17 |
| Performance Assessment of SARS-CoV-2 Detection Breath Biopsy - SARS-CoV-2 Study (COVID) |
Coronavirus disease 19 infection |
breath biopsy face masks with removable filters and fitted PVA strip alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Owlstone Nanotech Inc |
Onze Lieve Vrouwe Gasthuis Amsterdam, Universiteit Maastricht |
|
2020-08-31 |
2020-12-31 |
NCT04508556, SARS-COV-2 STUDY |
Phase Not Applicable |
Not yet recruiting |
0 |
4 Months |
500 |
Alexandra DeSaedeleer, Amerjit kang, Paul Bresser, Paul Savelkoul, |
2020-08-13 |
| To observe the outcome of Classical Ayurvedic medicine for the treatment of COVID-19 |
Coronavirus disease 19 infection |
Maha-Sudarshana Ghan Vati alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Shri Krishna Ayush University |
|
India |
2020-08-14 |
|
CTRI/2020/08/027044 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
100 |
Professor Dr Anil Sharma, Professor Dr Ashish Mehta, Professor Dr Baldev Kumar |
2020-08-13 |
| COREG: The McMaster Multi-Regional COVID-19 Hospital Case Registry |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
McMaster University |
Canadian Institutes of Health Research, Grand River Hospital, Hamilton Academic Health Sciences Organization, Hamilton Health Sciences Corp, Niagara Health System, St Josephs Healthcare Hamilton, St. Mary’s General Hospital |
Canada |
2020-04-15 |
2021-07-31 |
172754, COREG, NCT04508959 |
Phase Not Applicable |
Recruiting |
4 |
15 Months |
1500 |
Andrew P Costa, PhD, Darly Dash, MSc, Jessica Kapralik, MD (PGY5), Marla Beauchamp, PhD, Mats L Junek, MD, MSc, MyLinh Duong, MBBS, MSc, FRACP, Rebecca J Kruisselbrink, MD, MPH, FRCPC, Terence Ho, MD, FRCP, Tyler Pitre, MA, MD (PGIM) |
2020-08-13 |
| PREVENT-HD: A Study of Rivaroxaban to Reduce the Risk of Major Venous and Arterial Thrombotic Events, Hospitalization and Death in Medically Ill Outpatients With Acute, Symptomatic Coronavirus Disease 2019 (COVID-19) Infection |
Cerebrovascular disease, Coronary artery disease, Coronavirus disease 19 infection, Ischemic stroke, Peripheral vascular disease, Thromboembolism |
rivaroxaban alone, standard of care alone |
Factor Xa antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Janssen Research & Development LLC |
|
US |
2020-08-12 |
2021-04-06 |
39039039DVT3004, CR108849, NCT04508023, PREVENT-HD |
Phase 3 Clinical |
Not yet recruiting |
3 |
7 Months |
4000 |
Study Contact |
2020-08-13 |
| A clinical trial of eravacycline for potential treatment of SARS-CoV-2 infection (COVID-19) |
Coronavirus disease 19 infection |
repurposed eravacycline (COVID-19), SOM Biotech alone |
COVID19 replicase polyprotein 1a inhibitor, COVID19 replicase polyprotein 1ab inhibitor, Viral protease inhibitor |
|
SOM Biotech SL |
|
US, Europe |
|
|
|
Phase Not Applicable |
Planned |
1 |
|
|
|
2020-08-12 |
| Study to Evaluate the Safety, Tolerability and Pharmacokinetics of AZD-7442 in Healthy Adults |
Coronavirus disease 19 infection |
AZD-7442 alone |
COVID19 Spike glycoprotein inhibitor |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
AstraZeneca plc |
Biomedical Advanced Research and Development Authority (BARDA), Defense Advanced Research Projects Agency, PAREXEL International, US Department of Defense, US Department of Health and Human Services |
UK |
2020-08-17 |
2021-09-14 |
D8850C00001, NCT04507256 |
Phase 1 Clinical |
Recruiting |
1 |
12 Months |
48 |
AstraZeneca Clinical Study Information Center, Muna Albayaty, MBChB, FFPM, MSc |
2020-08-28 |
| Electronic Stethoscope Use During Intubation in Full Personal Protective Equipment |
Coronavirus disease 19 infection, Surgical procedure |
auscultation alone, electronic stethoscope alone, endobronchial blocker alone, endotracheal tube alone, fiberscope alone, general anesthesia alone, traditional stethoscope alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Taiwan University Hospital |
|
Taiwan |
2020-08-14 |
2021-07-31 |
202005104RINC, NCT04507958 |
Phase Not Applicable |
Not yet recruiting |
1 |
11 Months |
80 |
Chun-Yu Wu, PhD |
2020-08-14 |
| Online meditation as an aid in reducing symptoms of Depression, Anxiety and Psychological Stress in Resident Physicians during COVID-19 pandemic in Brazil |
Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression |
on-line meetings for meditation training alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
University of Sao Paulo |
|
Brazil |
2020-07-20 |
2020-09-30 |
33585620.0.0000.0045, 4.129.324, RBR-2w7ghc, U1111-1255-3186 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
44 |
Maria do Rosário Toscano von Flach |
2020-08-24 |
| A Survey to Assess Effects of Covid-19 on Cardiovascular Patients |
Cardiac failure, Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centro en Insuficiencia Cardiaca |
Fundación Clínica Médica Sur, Instituto Nacional de Cardiologia Ignacio Chavez |
Mexico |
2019-05-15 |
2021-07-15 |
20-1156, NCT04508920 |
Phase Not Applicable |
Recruiting |
1 |
26 Months |
76 |
ALAN FUENTES, MD, ALAN FUENTES-MENDOZA, MD, CHUQUIURE-VALENZUELA EDUARDO, MD, MSc, EDUARDO CHUQUIURE-VALENZUELA, MD, EDUARDO CHUQUIURE-VALENZUELA, MD MSc |
2020-08-13 |
| COVID SAFE: COVID-19 Screening Assessment for Exposure |
Coronavirus disease 19 infection |
saliva-based testing alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Pennsylvania |
|
US |
2020-08-31 |
2021-03-31 |
843565-OBS, COVID SAFE, NCT04508777 |
Phase Not Applicable |
Not yet recruiting |
1 |
7 Months |
600 |
Chalanda N Evans, BS, Mitesh S Patel, MD |
2020-08-14 |
| Effect of the Use of Anticoagulant Therapy During Hospitalization and Discharge in Patients With COVID-19 Infection |
Coronavirus disease 19 infection |
enoxaparin sodium alone |
Low molecular weight heparin |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Regional de Alta Especialidad de Ixtapaluca |
|
Mexico |
2020-06-20 |
2020-12-30 |
NCT04508439, NR-CEI-HRAEI-19-2020 |
Phase 2 Clinical |
Recruiting |
1 |
6 Months |
130 |
Omar O Ramos-Peñafiel, Omar Ramos-Peñafiel, Omar Ramos-Peñafiel, MD, PhD |
2020-08-13 |
| A clinical study to assess IgG1 Ab1 for the potential treatment of SARS-CoV-2 infection |
Coronavirus disease 19 infection |
IgG1 Ab1(COVID-19 infection) Abound bio/Saudivax alone |
|
|
University of Pittsburgh Medical Center |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-08-12 |
| Long-term Outcomes in Patients With COVID-19 |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Renji Hospital |
|
China |
2020-08-10 |
2021-08-31 |
COVID-19 PROGNOSIS, NCT04508712 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
900 |
Diansan Su, MD,PhD, Weifeng Yu, MD,PhD |
2020-08-20 |
| COVID-19 Associated Coagulopathy in Egypt |
Blood clotting disorder, Coronavirus disease 19 infection |
|
|
|
Assiut University |
|
Egypt |
2020-08-07 |
2020-10-31 |
17300413, NCT04507230 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
100 |
Azza Abdelaal, MD, PhD, Azza Ezzeldin, MD,PhD, Hanan Galal, MD, PhD |
2020-08-13 |