Last updated: Sep 23, 2020 - 02:00 BST

Title Indication Intervention Actions PatientSelection Sponsor Collaborator Country StartDate EndDate Identifiers Phase Recruitment Status Sites Trial Duration Enrollment Count Contacts LastChanged
COVID-NA: Changes in emergency department utilitzation during the COVID-19 pandemic Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Charite Universitaetsmedizin Berlin Germany 2020-03-01 COVID-NA, DRKS00023117, EA1/163/20 Phase Not Applicable Recruiting 0 1000000 Martin Möckel 2020-09-22
EDSAB-HOME: Evaluating home antibody test kits for the detection of coronavirus (COVID-19) antibodies Coronavirus disease 19 infection blood sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Public Health England National Institute for Health Research (NIHR) UK 2020-04-01 2021-06-01 CPMS 45951, IRAS 284980, EDSAB-HOME, ISRCTN56609224 Phase 2 Clinical Recruiting 0 14 Months 3000 Dr David Wyllie 2020-09-22
TURMERIC trial: Transcendental Meditation (TM) to reduce stress and improve immunity of health care providers during COVID-19 pandemic Acute stress disorder, Coronavirus disease 19 infection Transcendental Meditation (TM) alone, regular daily activities alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Medical Sciences India 2020-09-15 CTRI/2020/09/027910, TURMERIC trial Phase 2/Phase 3 Clinical Not yet recruiting 0 80 Dr Hemanga K Bhattacharjee, Rini Vohra 2020-09-22
Identification of Differences in Breath Components Detected With IMS in Patients Tested on SARS-CoV-2 Coronavirus disease 19 infection Ion Mobility Spectrometry alone, ultrasound-based spirometer alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) B Braun Melsungen AG Germany 2020-09-30 2021-03-31 HC-N-H-2004, NCT04556318 Phase Not Applicable Not yet recruiting 1 6 Months 100 Christoph Spinner, PD Dr., Study Manager 2020-09-22
RECOVIDS: Functional Recovery From Acute Respiratory Distress Syndrome (ARDS) Due to COVID-19: Influence of Socio-Economic Status Coronavirus disease 19 infection, Psychiatric disorder, Respiratory distress syndrome clinical examination alone, respiratory functional test alone, semi-directive interview alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire Dijon France 2020-09-30 2021-11-30 NCT04556513, QUENOT 2020, RECOVIDS Phase Not Applicable Not yet recruiting 0 14 Months 500 Jean-Pierre QUENOT, Pierre-Louis DECLERCQ 2020-09-22
imPulse Una Full-spectrum, Over Clothing E-stethoscope Coronavirus disease 19 infection Philips Lumify Ultrasound System alone, imPulse Una e-stethoscope alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Johns Hopkins University US 2020-09-22 2020-12-31 00110011, NCT04556149 Phase Not Applicable Not yet recruiting 1 3 Months 30 Ed Fuchs, MBA, Fuchs, MBA, Jumbe, PhD, Kelly Dooley, MD, PhD 2020-09-22
COVID-19 Ad Intervention Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of California Irvine The University of Hong Kong, University of California Los Angeles US 2020-09-29 2022-07-28 COVID-AD, NCT04555122 Phase Not Applicable Not yet recruiting 1 22 Months 52500 Arjuna Dugarte, Arjuna Ugarte 2020-09-22
CONFIN-AMP: Experience of Lock Down Related to the Covid-19 Epidemic and Its Impact on the Project of Parenthood Coronavirus disease 19 infection, Female infertility, Male infertility Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Regional Universitaire de Lille 2020-10-31 2020-12-31 2020-A01810-39, 2020_65, CONFIN-AMP, NCT04556630 Phase Not Applicable Not yet recruiting 0 2 Months 360 Bérengère DUCROCQ, MD 2020-09-22
Determining the Physical Activity Level of Healthy Adults During Pandemic Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Pamukkale University Turkey 2020-04-11 2020-08-20 2020/8/318, NCT04555954 Phase Not Applicable Completed 1 4 Months 205 EMEL TAŞVURAN HORATA, PhD, Emel TAŞVURAN HORATA 2020-09-22
ASPIRE: Performance Evaluation of LumiraDx SARS-CoV-2 Ag Test Coronavirus disease 19 infection LumiraDx SARS-CoV-2 Ag kit alone LumiraDx UK Ltd US 2020-06-26 2020-12-31 ASPIRE, NCT04557046, S-CLIN-PROT-00032 Phase Not Applicable Recruiting 7 6 Months 400 Andre Gvozden, Christopher Chappel, Daivd Craig, David Craig, Edward Zissman, Kimberley Henderson, Madhavi Ampajwala, Melanie Hoppers, Raechel Lapel, MPH, Robert Rosen 2020-09-22
MIND/COVID-19: Mental Health Impact and Needs Associated With COVID-19: a Comprehensive National Evaluation in Spain Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder, Suicide Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institut Municipal D'Investigació Mèdica (Imim) Fundacio Institut De Recerca De L'Hospital De La Santa Creu I Sant Pau, Fundacion Clinic per a la Recerca Biomédica, Generalitat de Cataluna, Hospital El Bierzo, Hospital General Universitario Gregorio Marañon, Hospital Torrecárdenas, Hospital Universitario 12 de Octubre, Hospital Universitario Araba(Spain), Hospital Universitario Donostia, Hospital Universitario Principe de Asturias, Hospital Vall D'Hebron, Hospital de Cruces, Hospital del Mar, Instituto de Salud Carlos III, Jordi Gol i Gurina Foundation, Parc Sanitari Sant Joan de Déu, Universitat Pompeu Fabra, University of Valencia Spain 2020-05-08 2021-05-31 2020/9203/I, NCT04556565 Phase Not Applicable Recruiting 18 12 Months 16000 Alma D. Martínez de Salazar, Ana González Pinto, Andrés Aragón Peña, Aurora Pérez Zapata, Consol Serra Pujadas, Cristina Rius Gibert, Eduard Vieta, Enric Aragonés Benaiges, Jordi Alonso, MD, Josep M. Haro Abad, José I. Emparanza Knörr, José Ignacio Pijoan Zubizarreta, José María Pelayo Terán, Juan de Dios Molina Martín, M. Isabel Del Cura González, Mara Parellada, Maria Teresa Puig Reixach, Meritxell Espuga Jordana, Mireia Campos Salanova, Nieves López Fresneña, Nieves Plana Farrás, Rafael M. Ortí Lucas, Víctor Pérez Solà 2020-09-22
Stress of Doctors in Covid era Acute stress disorder, Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Nizam's Institute of Medical Sciences India 2020-10-01 CTRI/2020/09/027907 Phase Not Applicable Not yet recruiting 1 300 Dr M Naveen Kumar, naveenjust@gmail.com 2020-09-22
Autologous whole blood injection as treatment for Covid-19 infection Coronavirus disease 19 infection Autologous whole blood injection alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) India 2020-10-02 CTRI/2020/09/027904 Phase 2 Clinical Not yet recruiting 1 60 Dr M Christopher 2020-09-22
Surgical Consent During the COVID-19 Pandemic Coronavirus disease 19 infection, Surgical procedure breast surgery alone, general surgery alone, vascular surgery alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Medway NHS Foundation Trust UK 2020-04-10 2020-08-14 2021.016N, NCT04556604 Phase Not Applicable Completed 1 4 Months 45 Oloruntobi Rotimi 2020-09-22
SHIFT-UC: A Study With GB-004 in Adult Subjects With Active Ulcerative Colitis (UC) Coronavirus disease 19 infection, Ulcerative colitis GB-004 alone HIF prolyl hydroxylase-2 inhibitor, Hypoxia inducible factor-1 stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gossamer Bio 2020-09-30 2022-04-30 2020-002306-12, GB004-2101, NCT04556383, SHIFT-UC Phase 2 Clinical Not yet recruiting 0 19 Months 195 Barrett Levesque, MD, Gossamer Bio, Inc 2020-09-22
Testing the efficacy and safety of a blood product COVID-19 Hyper-Immuneglobulin (Human) Solution in Participants with Active COVID-19 Coronavirus disease 19 infection COVID-19 Hyper-Immuneglobulin (Human) solution alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Intas Pharmaceuticals Ltd India 2020-09-22 0279-20, CTRI/2020/09/027903 Phase 2 Clinical Not yet recruiting 2 60 Dr Naman Shah, Dr Rajesh Gosavi, Dr Vipul Thakkar, Mr Prashant Modi 2020-09-22
A Review on Ct-value of rRT-PCR among COVID-19 cases in Terengganu Coronavirus disease 19 infection Sultanah Nur Zahirah Hospital Malaysia 2020-10-01 2020-12-31 56400, NMRR-20-1976-56400 Phase Not Applicable Status not specified 1 3 Months 90 Dr Wan Norliyana binti Wan Mahmud 2020-09-22
Epidemiological Analysis Coronavirus disease 19 infection Malaysia 2020-09-28 2020-10-28 56437, NMRR-20-1981-56437 Phase Not Applicable Status not specified 1 1 Month 121 Dr Mohamad Afiq Amsyar Bin Hamedin 2020-09-22
A randomized, double-blind, placebo-controlled, multicenter, phase III clinical study to assess safety and efficacy of favipiravir in the early treatment outpatient setting for adult COVID-19 infections ith mild to moderate symptoms Coronavirus disease 19 infection favipiravir alone RNA polymerase inhibitor Appili Therapeutics Inc US Phase 3 Clinical Planned 1 826 2020-09-22
New Treatment for COVID-19 Using Ethanol Vapor Inhalation Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure asprin plus ethanol vapor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Mansoura University Egypt 2020-10-01 2022-06-01 20.08.79, NCT04554433 Phase 3 Clinical Not yet recruiting 1 20 Months 80 Ragab 2020-09-22
NOXCOVID: A Dose-Escalation and Dose-Expansion Study of NOX-66 in the Treatment of COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome, Sepsis, Septic shock idronoxil (suppository, late-stage prostate cancer/soft tissue sarcoma/cancers/COVID-19-associated diseases), Noxopharm alone CASP8-FADD-like regulator inhibitor, Ecto NOX disulfide thiol exchanger 2 inhibitor, Sphingosine kinase inhibitor, Sphingosine-1-phosphate receptor-1 antagonist, Stimulator of interferon genes protein stimulator, Topoisomerase inhibitor, X-linked inhibitor of apoptosis protein inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Noxopharm Ltd 2020-09-30 2021-06-30 NCT04555213, NOX66-007, NOXCOVID Phase 1b Clinical Not yet recruiting 0 9 Months 40 Gisela Mautner, MD, PhD 2020-09-21
Hemodynamic Impact on Critical Care Patients With Lung Damage Secondary to COVID-19 Coronavirus disease 19 infection, Lung injury, Respiratory distress syndrome EV1000 alone, HemoSphere alone, radial artery cannulation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Andalusian Network for Design and Translation of Advanced Therapies Edwards Lifesciences Corp Spain 2020-10-01 2021-04-01 FAB-HEM-2020-01, NCT04556864 Phase Not Applicable Not yet recruiting 5 6 Months 67 Francisco Cota Delgado, MD, Francisco Javier Maynar, MD, Javier Ripollés-Melchor, MD, Juan Victor Lorente, Juan Victor Lorente, MD, Manuel Ignacio Monge García, MD, Mario Marquez, MD 2020-09-22
A multicenter, multi-national observational study to evaluate the correlation between COVID-19 infection and stroke risk Coronavirus disease 19 infection, Stroke Geisinger Health System Finland, Italy, Iran, Turkey, Canada, India, New Zealand, Brazil, Asia, North America, South America, Lebanon, US, Europe, Greece Phase Not Applicable Status not specified 11 26175 2020-09-22
CaVaR-Co19: Cardiovascular Risk Stratification in COVID-19 Cardiovascular disease, Coronavirus disease 19 infection COVID-19 test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Oregon Health Sciences University US 2020-06-08 2021-12-31 CaVaR-Co19, NCT04555187, STUDY00021368 Phase Not Applicable No longer recruiting 1 18 Months 60000 Larisa G Tereshchenko, MD, PhD 2020-09-21
COVID-19 Disease Duration and GIT Manifestations. A New Disease Severity Classification. An Egyptian Experience Bacterial infection, Coronavirus disease 19 infection, Gastrointestinal disease Empiric antibiotic therapy alone, anticoagulant therapy alone, Variable regimens including hydroxychloroquine , vitamin c , zinc Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cairo University Egypt 2020-06-01 2020-07-15 1004, NCT04554979 Phase Not Applicable Completed 2 1 Month 199 Ahmed M Abdul Ghani, MD, Hoda M abdel-Hamid, MD, Mahmoud Wahba, MD, Mohamed Tharwat Hegazy, MD, Mona M Hegazy, MD, Omar Ashoush, MD, Rania M Lithy, MD 2020-09-21
A phase I trial of MAN-19 to treat complications caused by COVID-19 Coronavirus disease 19 infection MAN-19 alone Tek tyrosine kinase receptor stimulator Q BioMed Inc Phase 1 Clinical Planned 0 2020-09-21
COVIDIG: COVID-19 Hyper-Immunoglobulin Coronavirus disease 19 infection, Viral pneumonia GC-5131A alone Immunoglobulin agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) GC Pharma South Korea 2020-09-20 2021-08-31 COVIDIG, GC5131A-HIG_P0201, NCT04555148 Phase 2a Clinical Recruiting 1 11 Months 60 Kyoung Ran Peck, Kyoung Ran Peck, Dr. 2020-09-22
Global Impact of COVID-19 on Pulmonology Special Units Coronavirus disease 19 infection Assiut University Egypt 2020-09-01 2020-12-30 ASSIUT20, NCT04554251 Phase Not Applicable Recruiting 1 3 Months 100 Aliae Mohamed-Hussein 2020-09-21
Evaluation of Levamisole efficacy in treatment of COVID-19 Coronavirus disease 19 infection Variable regimens including acetaminophen , diphenhydramine , hydroxychloroquine , levamisole Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Shahid Sadoughi University of Medical Sciences and Health Services Iran 2020-04-08 IR.SSU.REC.1399.063, IRCT20190810044500N7 Phase 2 Clinical Recruiting 1 50 Amirreza Roustaei Firouzabad, Fateme Saghafi, Masoud Mirzaei 2020-09-22
A phase II trial to evaluate rabeximod for the treatment of patients with covid-19 Coronavirus disease 19 infection rabeximod alone Cyxone AB Europe Phase 2 Clinical Planned 0 2020-09-21
Effect of plasmapheresis in the treatment of high-risk covid patients in Qom province Coronavirus disease 19 infection, Hypoxia FFP alone, plasmapheresis alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Ghoum University of Medical Sciences Iran 2020-03-29 IR.MUQ.REC.1399.057, IRCT20160118026097N5 Phase 3 Clinical No longer recruiting 1 60 Hasan adeli, hasan adeli, jamshid vafaeemanesh 2020-09-22
Convalescent Plasma for the Treatment of COVID-19 Coronavirus disease 19 infection COVID 19 Convalescent Plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Houston Methodist US 2020-03-20 2022-06-30 00025121, NCT04554992 Phase 1 Clinical No longer recruiting 1 27 Months 350 Eric Salazar, Eric Salazar, MD, PhD 2020-09-22
CONCOR-Donor: Convalescent Plasma for COVID-19 Research Donor Study Coronavirus disease 19 infection convalescent plasma alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hospital for Sick Children Canada 2020-06-30 2022-03-31 1000070462, CONCOR-Donor, NCT04555109 Phase Not Applicable Recruiting 1 21 Months 1000 Rulan Parekh, MD 2020-09-22
A Trial of GC-4419 in Patients With Critical Illness Due to COVID-19 Adult respiratory distress syndrome, Coronavirus disease 19 infection, Hypoxia, Respiratory failure avasopasem manganese alone Superoxide dismutase stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Galera Therapeutics Inc US 2020-09-09 2021-12-31 COV-4419-201, NCT04555096 Phase 2 Clinical Recruiting 1 15 Months 50 Amanda Sanders, Analyn Howells, George Matuschak, MD, Jon Holmlund, MD 2020-09-22
An observational study to determine the various clinical presentations of COVID 19 disease Coronavirus disease 19 infection clinical presentation analysis alone Zhangnan Hospital Phase Not Applicable Status not specified 0 11 2020-09-21
Periodontal problems in covid-positive but asymptomatic patients Coronavirus disease 19 infection, Periodontal disease Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Brazil 2020-09-07 1/09/2020, RBR-4scq8h, U1111-1257-5921 Phase Not Applicable Recruiting 1 40 Ana Suarez 2020-09-21
A Phase III Clinical Study to assess the Safety and Efficacy of Ayurvedic Tablets combined with the current available medicine and its impact on lab parameters in Subjects with Uncomplicated Moderate COVID-19 infection Coronavirus disease 19 infection BV-4051 alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Bioved Pharmaceuticals Inc India 2020-09-18 CTRI/2020/09/027817 Phase 3 Clinical Not yet recruiting 4 180 Dr Sujay Patil, DrN Kumarasamy, Rajeev Singh 2020-09-22
Study on placenta of women with coronavirus disease 2019 (COVID-19) Coronavirus disease 19 infection Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), African Ancestry India 2020-09-28 CTRI/2020/09/027862 Phase Not Applicable Not yet recruiting 1 150 Dr Ketki S Kulkarni 2020-09-22
Effect of Teleyoga on health care workers involved in Covid 19 duty Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression, Psychiatric disorder Tele yoga intervention alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) AIIMS Jodhpur India 2020-10-01 CTRI/2020/09/027842 Phase Not Applicable Not yet recruiting 1 60 Dr Naveen K H 2020-09-18
SARS-CoV2 infection Survey/2020: An observational, multicenter study on COVID 19 disease to study on HERD immunity Coronavirus disease 19 infection IgM test alone Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) India 2020-09-17 CTRI/2020/09/027881, SARS-CoV2 infection Survey/2020 Phase Not Applicable Not yet recruiting 1 1000 Dr Dhananjay Lad, Dr Vijaykumar Patil 2020-09-22
Epidemiological, Clinical and Molecular Characteristics of Patients With Acute Respiratory Failure Affected by 2019-NCOV Coronavirus disease 19 infection, Respiratory failure Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Istituto Clinico Humanitas Italy 2020-03-16 2023-07-31 2485, NCT04552340 Phase Not Applicable Recruiting 1 40 Months 1500 Maurizio Cecconi 2020-09-21
An observational study to evaluate the clinical characteristics of COVID-19 in patients with abnormal liver test results Coronavirus disease 19 infection National Clinical Research Center for Infectious Disease China Phase Not Applicable Status not specified 1 417 2020-09-21
COVID-Reims: COVID-19 Patient in Reims University Hospital in March to April 2020 Coronavirus disease 19 infection blood sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire de Reims France 2020-08-04 2022-05-31 COVID-Reims, NCT04553575, PO20124* Phase Not Applicable Recruiting 1 21 Months 499 Damien JOLLY, Damien Jolly 2020-09-21
Antibiotic Misuse During COVID-19 Pandemic: A Cross-sectional Survey Addressed to Community Pharmacists Coronavirus disease 19 infection, Prescription drug abuse Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Beni-Suef University Egypt 2020-07-20 2020-09-15 AA86, NCT04553055 Phase Not Applicable Completed 1 1 Month 413 Asmaa Abdelfattah Elsayed, Hoda M Rabie, PHD 2020-09-21
In this study IMMUACTIVE would be compared with an inert substance, as a supplement in treatment of COVID-19 patients Coronavirus disease 19 infection IMMUACTIVE alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Sami Labs Ltd India 2020-09-22 CPL/90/IMM_COVD/I/AUG/20, CTRI/2020/09/027841 Phase Not Applicable Not yet recruiting 3 100 Dr Ganesh Pratap, Dr Jayasree Krishnan c, Dr Kalpesh Shah, Dr Vivek G 2020-09-21
RIFIDS COVID-19 Terengganu Coronavirus disease 19 infection RT-PCR alone Malaysia 2020-09-30 2021-04-30 56040, NMRR-20-1970-56040 Phase Not Applicable Not yet recruiting 1 7 Months Wan Nor Hafizah Binti Wan Baharuddin 2020-09-22
Screening and prevention of osteonecrosis of the femoral head during novel coronavirus pneumonia (COVID-19) recovery Coronavirus disease 19 infection, Osteonecrosis, Viral pneumonia Jianpi Kanggu alone, Jintiange alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) The Third affiliated Hospital of Beijing Traditional Chinese Medicine University China 2020-09-01 2022-09-01 ChiCTR2000038333, ChiMCTR2000003937 Phase 0 Clinical Not yet recruiting 2 24 Months 120 Chen Weiheng, Xue Zhipeng 2020-09-21
Motion Modelling for Sedentary Behavior during the novel coronavirus pneumonia (COVID-19) pandemic: 10-min High Intensity Interval Training (HIIT) with Music Therapy (MT) Coronavirus disease 19 infection, Psychiatric disorder, Viral pneumonia High Intensity Interval Training (HIIT) with Music Therapy (MT) alone, sedentary task alone Healthy volunteers accepted, Young Adults (18-44 yrs) China 2020-08-01 2020-12-31 ChiCTR2000038256 Phase 0 Clinical Recruiting 1 5 Months 118 Liu Jialing 2020-09-21
Establishment of psychological assistance system for the bereaved during the COVID-19 epidemic Coronavirus disease 19 infection, Post traumatic stress disorder, Psychiatric disorder Grief online counselling alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Beijing Normal University China 2020-04-01 2020-12-31 ChiCTR2000038255 Phase Not Applicable Recruiting 1 9 Months 300 Jianping Wang 2020-09-22
COVID-VIT-D: Effect of Vitamin D on Morbidity and Mortality of the COVID-19 Coronavirus disease 19 infection vitamin D alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundación Para La Investigación E Innovación Biosanitaria En El Principado De Asturias (Finba) Hospital Universitario Central de Asturias, Instituto de Investigation Sanitaria del Principado de Asturias Spain 2020-04-04 2020-12-30 2020-019-PF-CAANJ, COVID-VIT-D, NCT04552951 Phase 4 Clinical Recruiting 1 8 Months 80 Jorge B Cannata-Andía, MD PhD, Juan Pérez-Ortega 2020-09-21
A Clinical Trial to Evaluate the effect of an Ayurvedic Regimen administered in (COVID–19) Patients Coronavirus disease 19 infection Variable regimens including Divya Anu Taila , Divya Coronil , Divya Swasari Vati Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Patanjali Research Foundation, Swami Vivekanand Subharti University India 2020-09-28 CTRI/2020/09/027882 Phase Not Applicable Not yet recruiting 1 150 Dr Gaurav Kapil, Dr Shirobhi Sharma 2020-09-21
ConCorD-19: The Containing Coronavirus Disease 19 (COVID-19) Trial Coronavirus disease 19 infection peginterferon beta-1a (multiple sclerosis), Biogen alone Interferon beta ligand Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Pontificia Universidad Catolica De Chile TVW Telethon Institute for Child Health Research Australia, Chile 2020-09-30 2021-12-31 200703013, ConCorD-19, NCT04552379 Phase 3 Clinical Not yet recruiting 2 15 Months 1240 Arturo Borzutzky, MD, Carolina Iturriaga, NP, Cecilia Perret, MD, Diego Garcia-Huidobro, MD,PhD, Eleanor N Fish, PhD, Jose A Castro Rodriguez, MD, PhD, Jose A Castro-Rodriguez, MD,PhD, Stephen Stick, MD, PhD, Stephen Stick, MD,PhD, Tobias Kollmann, MD,PhD 2020-09-21
A Clinical Trial of a Recombinant Adenovirus 5 Vectored COVID-19 Vaccine (Ad5-nCoV) With Two Doses in Healthy Adults Coronavirus disease 19 infection Ad5-nCoV alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institute of Biotechnology the Academy of Military Medical Sciences PLA Zhangnan Hospital China 2020-09-20 2021-06-30 AMMS85-2004, NCT04552366 Phase 1 Clinical Recruiting 1 9 Months 168 Jianying Huang, Ms, Jianyuan Wu, PhD, Lihua Hou, PhD, Xinghuan Wang, MD 2020-09-21
Psychological Impact of Institutional Quarantine as a Precautionary Measure Against COVID-19 Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Dr. Ram Manohar Lohia Hospital India 2020-09-20 2020-10-20 COVID, NCT04552392 Phase Not Applicable Not yet recruiting 1 1 Month 100 Pragya Sharma, PhD 2020-09-21
Omega-3, Nigella Sativa, Indian Costus, Quinine, Anise Seed, Deglycyrrhizinated Licorice, Artemisinin, Febrifugine on Immunity of Patients With COVID-19 Coronavirus disease 19 infection, Immune disorder, Respiratory disease, Viral pneumonia standard protocol based COVID-19 care alone, Variable regimens including Indian Costus , anise seed , artemisinin , deglycyrrhizinated licorice , docosahexaenoic acid , eicosapentaenoic acid , febrifugine , quinine , thymoquinone Young Adults (18-44 yrs) Beni-Suef University College of Pharmacy,Department of Pharmacy Practice,University of Arizona, Department of clinical pharmacy, faculty of pharmacy, Beni-suef univeristy, Maternity and Children Hospital, Makkah, University of Arizona Saudi Arabia 2020-09-20 2020-12-04 DOI: 10.31219/OSF.IO/U56FC, NCT04553705, TQ/OMEGA-3 ON COVID-19 Phase 2/Phase 3 Clinical Recruiting 1 2 Months 200 HASSAN Masmali [consultant of Pediatrics], M.D, HASSAN Masmali, M.D, MOHAMED M ABDELWAHAB GAMALELDIN, Ph.D Candidate, SHAIMAA M NASHAT SAYED ABDELHALIM, Candidate, SHAIMAA M NASHAT SAYED ABDELHALIM, Ph.D Candidate, SHAIMAA M Nashat SAYED ABDELHALIM, Ph.D Candidate 2020-09-21
A trial to evaluate a nasal spray vaccine for COVID-19 Coronavirus disease 19 infection COVID-19 vaccine alone Hong Kong University of Science & Technology China Phase Not Applicable Not yet recruiting 1 2020-09-18
Does dealing with the worldwide COVID-19-pandemic and alcohol stimuli trigger craving for alcohol for people with Alcohol Use Disorder? A comparative Eye-Tracking study Acute stress disorder, Alcoholism, Coronavirus disease 19 infection, Psychiatric disorder Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University Of Mannheim/Heidelberg Germany 2020-09-19 2020-612N, DRKS00023092 Phase Not Applicable Not yet recruiting 0 30 Patrick Bach 2020-09-22
A Phase 1, Followed by a Phase 2, vaccine given Randomly in subjects in different sites to Evaluate the Safety, side effects, and resistance of the Virus Vaccine, BBV152D Administered between the layers of the skin(intradermal) in Healthy Volunteers Coronavirus disease 19 infection SARS-CoV- 2 Virus Vaccine, BBV152D alone Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Bharat Biotech International Ltd India 2020-09-08 BBIL/BBV152D-B/2020 Version: 3.0, CTRI/2020/09/027674 Phase 1/Phase 2 Clinical Recruiting 4 124 Dr Krishna Mohan 2020-09-21
Short-Term Low Dose Corticosteroids for Management of Post covid19 Pulmonary Fibrosis Coronavirus disease 19 infection prednisolone alone, symptomatic treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) South Valley University Egypt 2020-04-01 2020-07-30 NCT04551781, SVU-MED-CHT019420861 Phase 2 Clinical Completed 1 3 Months 450 alaa DR Rashad, MD 2020-09-21
REsCue: Safety and Efficacy of Rayaldee for Treating Mild to Moderate COVID-19 Coronavirus disease 19 infection calcifediol (oral, vitamin D insufficiency), OPKO alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) OPKO Health Inc US 2020-09-30 2021-04-30 CTAP101-CL-2014, NCT04551911, REsCue Phase 2 Clinical Not yet recruiting 1 7 Months 160 Akhtar Ashfaq, MD FACP FASN, Lawrence Reiter, PhD RQAP-GCP 2020-09-21
Effectiveness of Shallomin syrup on patients affected by COVID-19 Coronavirus disease 19 infection Current protocol drug therapy alone, shallomin syrup alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ahvaz University of Medical Sciences Iran 2020-08-10 IR.AJUMS.REC.1398.995, IRCT20200504047295N1 Phase 3 Clinical No longer recruiting 3 90 Afshin Talebi, Mansour Amin, Mohammad Badavi, Mohammad Jafar Yadyad 2020-09-22
ZnCOVID-19: Zinc Versus Multivitamin Micronutrient Supplementation in the Setting of COVID-19 Coronavirus disease 19 infection Centrum Adult alone, zincPreserVision AREDS alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mayo Clinic Foundation US 2020-09-14 2021-05-14 20-004637, NCT04551339, ZnCOVID-19 Phase Not Applicable Recruiting 1 8 Months 4500 Atta Behfar, MD, PhD 2020-09-21
TELEGERIATRY: Telehealth for patients with dementia at the Hospital Universitário Walter Cantidio-UFC Coronavirus disease 19 infection, Dementia telemedicine alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Federal University of Ceara Brazil 2020-06-17 31779920.1.0000.5045, 4.093.069, RBR-9xs978, TELEGERIATRY, U1111-1254-1141 Phase 1/Phase 2 Clinical Recruiting 1 200 Danielle Pessoa Lima, Jarbas de Sá Roriz Filho 2020-09-19
A clinical trial of Sputnik V in children for the treatment of COVID-19 Coronavirus disease 19 infection Sputnik V alone COVID19 Spike glycoprotein modulator Gamalei Institute of Epidemiology and Microbiology Phase Not Applicable Planned 0 2020-09-18
Safety and Efficacy of Ivermectin and Doxycycline in Treatment of Covid-19 Coronavirus disease 19 infection antihistamine therapy alone, Variable regimens including doxycycline hyclate , ivermectin , montelukast sodium , paracetamol , vitamin C , vitamin D Chloride channel modulator, Leukotriene D4 antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bangladesh Medical Research Council (BMRC) Bangladesh 2020-09-30 2020-12-31 31211062020, NCT04551755 Phase 2 Clinical Not yet recruiting 1 3 Months 188 Abdul Basit Ibne Momen, MRCP, Mohammad Tarek Alam, MD 2020-09-19
Pulsed, inhaled nitric oxide (iNO) for the treatment of patients with mild or moderate corona virus disease (COVID-19) Coronavirus disease 19 infection INOpulse alone, high resolution computed tomography (HRCT) alone, inhaled nitric oxide (iNO) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bellerophon Pulse Technologies Belgium 2020-06-22 2020-002394-94, PULSE-IIT-FluidDA-001 Phase 2 Clinical Recruiting 1 6 Clinical Trial Information Desk 2020-09-18
The Effect of COVID-19 Pandemic on Adolescent and Young Adult Cancer Patients and Survivors Acute stress disorder, Cancer, Coronavirus disease 19 infection Young Adults (18-44 yrs) MD Anderson Cancer Center National Cancer Institute US 2020-07-13 2021-12-31 2020-0504, NCI-2020-06609, NCT04551378 Phase Not Applicable Recruiting 1 17 Months 600 Maria Swartz 2020-09-21
Music Therapy in Frontline Healthcare Workers Coronavirus disease 19 infection, Psychiatric disorder Music Therapy alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Simon Fraser University Canada 2020-10-01 2020-11-30 H20-02015, NCT04551274 Phase Not Applicable Not yet recruiting 1 2 Months 20 Glen Chapman, PhD, Ryan CN D'Arcy, PhD, Ryan CN D'Arvy, PhD, Shaun D Fickling, PhD 2020-09-17
Feasibility and Safety of High-intensity Exercise Training in Patients Surviving COVID-19 Coronavirus disease 19 infection Exercise training alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rigshospitalet, Denmark Denmark 2020-09-09 2021-05-01 75068, H-20033733, NCT04549337 Phase Not Applicable Not yet recruiting 1 7 Months 10 Regitse Christensen, MD PhD, Ronan Berg, MD PhD 2020-09-22
The efficacy of bromhexine hydrochloride in the prevention of COVID-19 disease Coronavirus disease 19 infection, Dyspnea, Respiratory distress syndrome, Viral pneumonia bromhexine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tabriz University of Medical Sciences Iran 2020-04-20 IR.TBZMED.REC.1399.553, IRCT20200317046797N7 Phase 2 Clinical No longer recruiting 1 3500 Dr Khalil Ansarin, Dr Mohammad Samiei, Sepideh Zununi Vahed 2020-09-22
CONSCIENCE: Prevalence of COVID-19 (Coronavirus Disease 19) in Pregnant Women on Labor in a Public Hospital in Chile (Coronavirus Disease Covid-19 Pandemic in Chile) Coronavirus disease 19 infection, Parturition, Premature labor Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Hospital San Juan de Dios, Santiago Chile 2020-04-15 2020-07-15 CONSCIENCE, COVID 19 PREGNANCY HSJD CHILE, NCT04551690 Phase Not Applicable Completed 1 3 Months 720 Helga Vera von Bargen, Helga Vera von Bargen, physician 2020-09-21
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Neutralizing Antibody BGB DXP-593 in Participants With Mild-to-Moderate Coronavirus Disease 2019 (COVID-19) Coronavirus disease 19 infection DXP-593 alone COVID19 Spike glycoprotein modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) BeiGene Co Ltd 2020-10-30 2021-02-28 BGB-DXP593-102, NCT04551898 Phase 2 Clinical Not yet recruiting 0 4 Months 180 BeiGene, Zhen Yao, MD 2020-09-21
Safety and Immunogenicity Study of Inactivated Vaccine for Prevention of COVID-19 Coronavirus disease 19 infection CoronaVac alone Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) Dynavax Technologies Corp, Sinovac Research & Development Co Ltd Medigen Vaccine Biologics Corp China 2020-09-28 2021-09-30 NCT04551547, PRO-NCOV-1003 Phase 1/Phase 2 Clinical Not yet recruiting 1 12 Months 552 Hui Jin, Yuliang Zhao, Master 2020-09-21
A trial to evaluate HFB-30132A for the treatment of SARS-CoV-2 infection (COVID-19) patients Coronavirus disease 19 infection HFB-30132A alone Angiotensin converting enzyme 2 inhibitor, COVID19 Spike glycoprotein inhibitor HiFiBio Phase Not Applicable Planned 0 2020-09-17
A phase I trial to evaluate mRNA-based COVID-19 vaccine, Vaxess Technologies for the prevention of COVID-19 Coronavirus disease 19 infection COVID-19 vaccine (MIMIX/sustained-release), Vaxess Technologies alone Vaxess Technologies Inc US Phase 1 Clinical Planned 1 2020-09-18
Study to Evaluate the Safety and Efficacy of Virazole in Hospitalized Adult Participants With Respiratory Distress Due to COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome ribavirin (inhalation solution, respiratory syncytial virus infection), Bausch Health alone Inosine monophosphate dehydrogenase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bausch Health Americas, Inc. 2020-09-30 2021-04-30 BHC-RIB-5401-GL, NCT04551768 Phase 1 Clinical Not yet recruiting 0 7 Months 50 Anya Loncaric, Francisco Figueroa 2020-09-18
Non-invasive Biometric Monitoring in Nursing Homes to Fight COVID-19 Coronavirus disease 19 infection, Viral respiratory tract infection Biostrap wristband alone, Emfit device alone Healthy volunteers accepted US 2020-09-30 2021-02-26 HSA-001, NCT04548895 Phase Not Applicable Not yet recruiting 1 4 Months 30 Martin G Frasch, Martin G Frasch, MD, PhD 2020-09-18
Avigan Trial Coronavirus disease 19 infection favipiravir alone, supportive care alone RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Department of Health, Philippines, University of the Philippines Philippines 2020-09-01 2021-06-30 2020-CT0542, PHRR200911-002930 Phase 3 Clinical Not yet recruiting 1 10 Months 96 Regina P. Berba, MD 2020-09-21
Sleep Quality Among HCWs Coronavirus disease 19 infection, Insomnia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Zagazig University Ministry of Health in Kuwait Egypt 2020-05-19 2020-09-05 2020/1464, NCT04549350 Phase Not Applicable Completed 1 3 Months 217 Ahmad Abbas 2020-09-18
MLK: Montelukast in COVID-19 Coronavirus disease 19 infection Supportive treatment alone, lopinavir + ritonavir plus montelukast sodium HIV protease inhibitor, Leukotriene D4 antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Babol University of Medical Sciences Iran 2020-07-21 IR.MUBABOL.REC.1399.222, IRCT20180624040213N2, MLK Phase 3 Clinical Recruiting 1 114 Hossein Najafzadehvarzi, Reza Ghadimi 2020-09-18
Verification of the efficacy of Bromhexine hydrochloride in treatment of patients with COVID-19 disease Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia bromhexine hydrochloride alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tabriz University of Medical Sciences Ministry of Health and Medical Education, IRAN Iran 2020-09-22 IR.TBZMED.REC.1399.553, IRCT20200818048444N1 Phase 3 Clinical Recruiting 1 1300 Dr. Mohammad Samiei, Khalil Ansarin, Khalil ansarin 2020-09-22
An observational, retrospective, cohort study to investigate differences in manifestations and outcomes of coronavirus disease 2019 (COVID-19) infection between those with and without rheumatic disease: a comparative cohort study from a US 'hot spot' Coronavirus disease 19 infection, Rheumatoid arthritis Massachusetts General Hospital Phase Not Applicable Status not specified 0 156 2020-09-16
TXACOVIDPREV: Antiviral Effects of TXA as a Preventative Treatment Following COVID-19 Exposure Coronavirus disease 19 infection apixaban plus tranexamic acid Factor Xa antagonist Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Alabama at Birmingham US 2020-12-01 2023-03-31 NCT04550338, TXA.COVID.3, TXACOVIDPREV Phase 3 Clinical Not yet recruiting 1 28 Months 100 Timothy J Ness, MD PhD, Timothy Ness 2020-09-17
A first in human, phase I trial to evaluate the safety and pharmacokinetic of BHV-3500 for the treatment of patients with Coronavirus disease 19 infection and migraine Coronavirus disease 19 infection, Migraine CGRP receptor antagonist (intranasal, migraine/COVID-19), BioHaven alone CGRP receptor antagonist Biohaven Pharmaceutical Holding Co Ltd US 2020-09-10 Phase 1 Clinical Recruiting 1 2020-09-16
A study to evaluate efficacy and safety of etoposide treatment adjunctive to immunosuppressants for a small cohort of critically ill COVID-19 acute respiratory distress syndrome (ARDS) patients presenting with systemic hyperinflammation Adult respiratory distress syndrome, Coronavirus disease 19 infection etoposide phosphate alone Topoisomerase II inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Universitario de Burgos Spain Phase Not Applicable Status not specified 1 11 2020-09-16
ASKCOV: Antisense Therapy to Block the Kallikrein-kinin Pathway in COVID-19 Coronavirus disease 19 infection IONIS-PKK-LRx alone KLKB1 gene inhibitor, Plasma kallikrein inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital do Coracao Instituto de Educação e Pesquisa do Hospital Moinhos de Vento, Ionis Pharmaceuticals Inc US 2020-10-31 2021-12-31 ASKCOV, ASKCOV-TRIAL, NCT04549922 Phase 2b Clinical Not yet recruiting 1 14 Months 90 Alexandre B Cavalcanti, Fernando G Zampieri, MD, Samara P Gomes 2020-09-17
VEP-COV: Virucidal Effect of Povidone-Iodine on COVID-19 In-Vivo Coronavirus disease 19 infection povidone-iodine alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dhaka medical college Bangladesh 2020-07-01 2020-10-30 NCT04549376, PIRCC-1131-2020, VEP-COV Phase 2 Clinical Recruiting 1 3 Months 200 Brig. General Dr. AKM Nasir Uddin, MBBS,MPH, Mohammad Jahid Hasan, MBBS,MPH, Mostafa Kamal Arefin, MBBS,FCPS, Prof Sk Nurul Fattah Rumi, MBBS, MS 2020-09-17
POCAH-COVID: Prevalence Of COVID-19 Among Health-workers in a French General Hospital Coronavirus disease 19 infection RT PCR alone, serology testing alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) France 2020-08-03 2021-06-30 NCT04548908, POCAH-COVID, POCAH-COVID19 Phase Not Applicable Recruiting 1 10 Months 1300 Delphine LEMAIRE-BRUNEL 2020-09-17
MISTIC: Infusions of Mesenchymal Stromal Cells in Children With Multisystem Inflammatory Syndrome Coronavirus disease 19 infection, Inflammatory disease Variable regimens including allogenic human cord tissue derived mesenchymal stromal cells (iv, ARDS asssociated with COVID-19), Duke University , cetirizine , hydrocortisone Histamine H1 receptor antagonist Young Adults (18-44 yrs) Duke University US 2020-11-01 2021-02-01 MISTIC, NCT04549285, PRO00106044 Phase 1 Clinical Not yet recruiting 2 3 Months 6 Edwin Horwitz, MD, PhD, Jennifer Baker, RN, Jessica Sun, MD, Joanne Kurtzberg, MD, Mitchell S. Cairo, MD 2020-09-18
Safety, PK and PD of Kamada Anti-SARS-CoV-2 in COVID-19 Coronavirus disease 19 infection, Viral pneumonia plasma-derived anti-SARS-CoV-2 IgG (COVID-19), Kedrion Biopharma/Kamada alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kamada Ltd Israel 2020-08-05 2021-02-28 KAMADA ANTI-SARS-COV-2-001, NCT04550325 Phase 1/Phase 2 Clinical No longer recruiting 4 6 Months 12 Sharon Castro, MSc 2020-09-17
Effect of Wearing Personal Protective Equipment (PPE) on CPR Quality in Times of the COVID-19-pandemic Coronavirus disease 19 infection Cardiopulmonary resuscitation with wearing personal protective equipment (PPE) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Institute of Mountain Emergency Medicine Italy 2020-09-13 2020-12-31 CPR PPE, NCT04548934 Phase Not Applicable Not yet recruiting 1 3 Months 28 Giacomo Strapazzon, MD, PhD, Simon Rauch, MD, PhD 2020-09-17
Survey about SARS-CoV2 / Covid-19 Coronavirus disease 19 infection Switzerland, Austria, Germany 2020-09-21 A 2020-0205, DRKS00023087 Phase Not Applicable Not yet recruiting 3 1000 Hans-Jürgen Thiesen 2020-09-21
SAMILCOV: Study of the Analytical Performance of Different Salivary Self-collection Methods for the Detection of COVID-19 Coronavirus disease 19 infection saliva sampling alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Direction Centrale du Service de Sante des Armees France 2020-09-15 2020-10-15 2020-COVID19-36, NCT04550390, SAMILCOV Phase Not Applicable Recruiting 4 1 Month 2400 Audrey MERENS, MD, Eric GARNOTEL, MD, Frédéric JANVIER, MD, Vincent FOISSAUD, MD 2020-09-21
LOWACM: A low-intervention study of pre-exposure prophylaxis (PrEP) in healthy volunteers at high risk of coronavirus (SARS-CoV-2) infection. Coronavirus disease 19 infection inosine-glutamyl-cysteinyl-glycine disodium plus potassium chloride Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) North-Western State Medical University Russian Federation 2020-04-22 2020-09-02 ISRCTN34160010, LOWACM, MIBVD-19 Phase 2 Clinical Completed 2 4 Months 100 Dr Nataliya Shvetc, Dr Veronika Gomonova, Prof Dubina 2020-09-21
COVID-19 Related Lung Ventilation and Perfusion Injury Asthma, Coronavirus disease 19 infection Airwave Oscillometry alone, Plethysmography alone, Spirometry alone, V/Q SPECT-CT alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) McMaster University Cyclomedica Australia PTY Ltd Canada 2020-09-18 2021-12-31 FIRH002, NCT04549636 Phase Not Applicable Recruiting 1 15 Months 92 Christopher Marriott, MD, PhD, Manali Mukherjee, PhD, Parameswaran Nair, MD, PhD, Sarah Svenningsen, PhD, Terence Ho, MSc, MD 2020-09-17
GEN-COVID: Genetic Bases of COVID-19 Clinical Variability Coronavirus disease 19 infection Genome wide association studies alone, Whole exome sequencing alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Siena ASST Fatebenefratelli Sacco, Azienda Ospedaliera Ospedale Maggiore di Crema, Azienda Ospedaliera Universitaria Senese, Azienda Ospedaliera dei Colli Monaldi-Cotugno-CTO, Azienda Ospedaliera di Perugia, Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia, Azienda USL Toscana Centro, Cardarelli Hospital, Ceinge Biotecnologie Avanzate Scarl, Fondazione IRCCS Policlinico San Matteo, IRCCS AOU San Martino – IST, IRCCS Istituto Giannina Gaslini, IRCCS L Spallanzani, Irccs Casa Sollievo Della Sofferenza, Istituti Ospitalieri Di Cremona, Istituto Auxologico Italiano, Ospedale San Donato, Ospedale dell'Angelo, Ospedale della Misericordia, Policlinico Universitario Agostino Gemelli, University of Modena and Reggio Emilia Finland, Italy 2020-04-08 2026-04-08 16917, GEN-COVID, NCT04549831 Phase Not Applicable Recruiting 2 72 Months 2000 Alessandra Renieri, MD, PhD, Francesca Mari, MD, PhD 2020-09-18
Clinical Phenotype and Outcomes of Inpatients With COVID-19 and Diabetes Coronavirus disease 19 infection, Diabetes mellitus Azienda Ospedaliero-Universitaria di Parma Italy 2020-07-30 2020-12-31 27557, NCT04550403 Phase Not Applicable Recruiting 1 5 Months 700 Alessandra Dei Cas, MD, PhD, Raffaella Aldigeri, MSc, Riccardo Bonadonna, MD, PhD, Tiziana Meschi, MD 2020-09-17
The Impact of Lifestyle Changes on Non-COVID Deaths Coronavirus disease 19 infection Lifestyle alteration alone Healthy volunteers accepted Jiangsu Provincial People’s Hospital China 2020-09-30 2020-10-31 NCT04550312, XYFY2020-KL142-01 Phase Not Applicable Recruiting 2 1 Month 80000 Chenzong Li, PHD, Ming Chu, PHD, ming chu, PHD, minglong chen, PHD 2020-09-17
A phase I Study of GIGA-2050 for the potential treatment of COVID-19 Coronavirus disease 19 infection GIGA-2050 alone GigaGen Inc Phase 1 Clinical Planned 0 2020-09-16
Recombinant New Coronavirus Vaccine (CHO Cells) to Prevent SARS-CoV-2 Phase I Clinical Trial (>/= 60 Years Old) Coronavirus disease 19 infection, Respiratory disease recombinant new coronavirus vaccine alone Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Anhui Zhifei Longcom Biopharmaceutical Co Ltd China 2020-08-19 2021-12-31 LKM-2020-NCV03, NCT04550351 Phase 1/Phase 2 Clinical Recruiting 1 16 Months 50 Fang Jun Li, Undergraduate, fangjun Li 2020-09-21
The March 15 Study: Examining the impacts and recovery from the March 15 2019 Christchurch Mosque attacks in people most directly exposed and their adult family members Agoraphobia, Anxiety disorder, Bipolar disorder, Coronavirus disease 19 infection, Depression, Obsessive compulsive disorder, Panic disorder, Post traumatic stress disorder, Psychotic disorder, Social phobia semi-structured diagnostic interview alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Otago Health Research Council of New Zealand New Zealand 2020-09-28 ACTRN12620000909921, M15, U1111-1255-8902 Phase Not Applicable Not yet recruiting 1 600 A/Prof Caroline Bell 2020-09-18
A phase II/III study to evaluate the safety and efficacy of UB-612 for the potential prevention of COVID-19 infection Coronavirus disease 19 infection UB-612 alone COVID19 Spike glycoprotein modulator, HLA class I antigen modulator, HLA class II antigen modulator DASA (US) Covaxx Brazil Phase 2/Phase 3 Clinical Planned 1 2020-09-16
COL: Corona Onderzoek Limburg Coronavirus disease 19 infection questionnaire alone, venepuncture alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Netherlands 2020-09-10 2020-12-31 COL, METC 20-071, NL8889 Phase Not Applicable Not yet recruiting 1 3 Months 10000 Nicole Dukers-Muijrers 2020-09-17
The psychological well-being and health-related quality of life of patients admitted to the hospital with COVID-19 Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Franciscus Gasthuis & Vlietland BeterKeten Netherlands 2020-05-28 2021-09-30 2020-042, NL8882 Phase Not Applicable No longer recruiting 1 16 Months 250 Johan Vlake 2020-09-17
Study on Incidence of Elective Surgery Postponed During COVID-19 Pandemic in Geriatric Population Coronavirus disease 19 infection, Psychiatric disorder, Surgical procedure elective surgery alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Malaya Malaysia 2020-06-22 2020-12-31 2020623-8801, NCT04547218 Phase Not Applicable Recruiting 1 6 Months 150 Dhurgka Ramasamy, Hui Min Khor, Pui San Loh, FANZCA 2020-09-20
Inpatient Treatment With Anti-Coronavirus Immunoglobulin (ITAC) Coronavirus disease 19 infection hyperimmune intravenous immunoglobulin (hIVIG) plus remdesivir COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Minnesota International Network for Strategic Initiatives in Global HIV Trials (INSIGHT), National Institute of Allergy and Infectious Diseases, National Institutes of Health Denmark, US, Argentina, UK 2020-09-30 2021-07-31 INSIGHT 013, NCT04546581 Phase 3 Clinical Not yet recruiting 4 10 Months 500 Edward Gardner, MD, Eileen Denning, Jacqueline Nordwall, James Neaton, PhD, Jens Lundgren, MD, DMSc, Marcelo Losso, MD, Sarah Prett, MD 2020-09-17
NSpectroCovid: Study of Morphological, Spectral and Metabolic Manifestations of Neurological Complications in COVID-19 Patients Brain injury, Coronavirus disease 19 infection Magnetic Resonance Spectroscopy (MRS) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire D Amiens France 2020-09-08 2022-05-31 NCT04546737, NSpectroCovid, PI2020_843_0087 Phase Not Applicable Recruiting 1 20 Months 20 Jean-Marc CONSTANS, Pr, Jean-Marc Constans, Pr 2020-09-18
Biomodulin T in the elderly for protection in events of local transmission of COVID-19 Coronavirus disease 19 infection Biomodulin T alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Biopreparations Center Ministerio de Salud Publica Cuba 2020-09-11 2020-12-31 GEC2020BMT028, RPCEC00000334 Phase Not Applicable Not yet recruiting 1 3 Months Luis Philip Heredia Guerra, Mary Carmen Reyes Zamora 2020-09-16
Evaluation and Promotion of Adolescents Mental Health Under the COVID-19 Coronavirus disease 19 infection, Psychiatric disorder Psychology teaching alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Shenzhen University China 2020-09-07 2020-12-31 ChiCTR2000038069 Phase 1 Clinical Recruiting 1 3 Months 180 Qiaomin Huang, Xinli Chi 2020-09-16
PLACOVID: Convalescent Plasma for Severe COVID-19 Patients Coronavirus disease 19 infection best supportive care alone, convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital de Clinicas de Porto Alegre Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul Brazil 2020-07-16 2021-10-31 2020-0158, NCT04547660, PLACOVID Phase 3 Clinical Recruiting 1 15 Months 160 Alexandre P Zavascki, PhD, Júlia P Portich, MD, Leo Sekine, PhD 2020-09-16
A trial to evaluate DS-2319 for the treatment of patients with COVID-19 Coronavirus disease 19 infection DS-2319 alone Serine protease inhibitor Daiichi Sankyo Co Ltd Japan 2021-03-31 Phase Not Applicable Planned 1 2020-09-15
Intravenous Immunoglobulins for the Treatment of Covid-19 Patients: a Clinical Trial Coronavirus disease 19 infection IVIG, Amson Vaccine and Pharma Ltd alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Health Sciences Lahore University of Lahore, Main Campus Pakistan 2020-09-15 2020-11-15 NCT04548557, UNIVERSITYHSL-IVIG Phase 3 Clinical Not yet recruiting 1 2 Months 60 Fridoon J Ahmad, Ph.D, Fridoon Jawad Ahmad, PhD, Gibran Sheikh, PhD, Hassan Ahmad Khan, M.Phil, Javed Akram, MBBS,FRCP,MRCP, Javed Akram, MBBS,FRCS,MRCP, Muhammad Akram Tariq, PhD, Riffat Mehboob, PhD, Riffat o Mehboob, PhD, Syed Amir Gilani, PhD, riffat mehboob, Ph.D 2020-09-16
Study to Evaluate the Safety and Efficacy of Liquid Alpha-1 Proteinase Inhibitor (Human) in Hospitalized Participants With Coronavirus Disease (COVID-19) Coronavirus disease 19 infection Prolastin alone, standard of care medical treatment alone Alpha 1 proteinase inhibitor, Serine protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Grifols Therapeutics Inc, USA 2020-09-30 2021-09-30 GC2006, NCT04547140 Phase 2 Clinical Not yet recruiting 0 12 Months 100 Elsa Mondou, Susan Sorrells 2020-09-16
The Validity of Modern Mobile Applications in Management of COVID-19 Home Isolation Patients: a Survey for Health Care Professionals Coronavirus disease 19 infection mobile application use alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ain Shams University Egypt 2020-09-14 2021-01-31 75 / 2020, NCT04548492 Phase Not Applicable Not yet recruiting 1 4 Months 175 Mona Ammar 2020-09-16
Psychodiagnostic Screening in U-Examinations Coronavirus disease 19 infection, Psychiatric disorder U7a Screening alone, U8 Screening alone, U9 Screening alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitätsklinikum Hamburg-Eppendorf German Ministry of Health, Universitätsklinikum Schleswig-Holstein Germany 2020-10-01 DRKS00022553, LPEK-0117 Phase 4 Clinical Recruiting 2 5670 Silke Pawils 2020-09-16
TASC-3B: Trace element ATORG Study COVID-19 in Berlin, Bavaria, and Baden-Württemberg: Characterization of COVID-19 infections using parameters of the immune system and trace element status Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia antibody test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Klinikum Aschaffenburg Charite Universitaetsmedizin Berlin, University of Heidelberg, University of Zurich Germany 2020-06-22 20033, DRKS00022294, TASC-3B, U1111-1254-2975 Phase Not Applicable Recruiting 1 300 Raban Heller 2020-09-16
Evaluation of the possibility to gain specimen for SARS-CoV-2 PCR from Aerosol/droplets with a sugar matrix that is applied to a face mask Coronavirus disease 19 infection Pharyngeal swabs alone, SARS-CoV-2 PCR alone, face mask alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Jena Germany 2020-09-09 2020-1877-BO, DRKS00023033 Phase 2 Clinical Recruiting 1 10 Andreas Kortgen 2020-09-16
A Study to Evaluate Safety and Efficacy of Convalescent Methylene Blue Treated (MBT) Plasma From Donors Recovered From Coronavirus Disease 2019 (COVID-19) Coronavirus disease 19 infection convalescent anti-SARS-CoV-2 MBT plasma alone, standard medical treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Grifols SA Grifols Therapeutics Inc, USA Spain 2020-04-29 2020-12-31 2020-001299-14, GC2003, NCT04547127 Phase 2 Clinical Recruiting 9 8 Months 100 Adrian Alegre, MD, Cristobal Galban, MD, Elsa Mondou, Jesus Caballero, MD, Juan j Jimenez, MD, Manuel Quintana, MD, Miguel Sanchez, MD, Mireia Torres, Pilar Llamas, MD, Rafael Manez, MD, Ricard Ferrer, MD 2020-09-16
Strength and course of the SARS CoV-specific immune response after infection Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institut für Virologie, Universitätsklinikum Leipzig Germany 2020-09-09 352/20-ek, DRKS00023047 Phase Not Applicable Recruiting 1 60 Christian Jassoy 2020-09-17
Coronary heart disease management during the Corona Pandemic (COVID-19) Acute stress disorder, Coronavirus disease 19 infection, Ischemic heart disease structured disease management program (DMP-CHD) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Leipzig Germany 2020-09-15 397/20-ek, DRKS00023001 Phase Not Applicable Recruiting 1 400 Anne Schrimpf, Markus Bleckwenn 2020-09-16
The role of attentional bias in relation to health anxiety and health practices among cancer patients during the outbreak of the novel coronavirus (COVID-19) Anxiety disorder, Coronavirus disease 19 infection Questionnaire survey alone The University of Hong Kong Hong Kong 2020-04-15 2020-12-31 HKUCTR-2899, UW 20-254 Phase Not Applicable Not yet recruiting 1 8 Months 410 HKUCTR Administrator, Ms. Wing-lam Danielle Ng 2020-09-18
CIS: COVID-19 infection survey of the UK general population Coronavirus disease 19 infection swabs testing alone Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Oxford NIHR Biomedical Research Centre, Oxford, NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Public Health England, The Scottish government, Welsh Government UK 2020-04-14 2023-04-23 CIS, CPMS 46962, IRAS 283248, ISRCTN21086382 Phase Not Applicable Recruiting 2 36 Months 500000 Prof SarahWalker 2020-09-21
CoPS: COVID-19 Persistence in Stool Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Quadram Institute Bioscience Norfolk and Norwich University Hospitals NHS Foundation Trust UK 2020-09-08 2022-06-30 CoPS, NCT04546776, QIB05/2020 Phase Not Applicable Recruiting 2 21 Months 200 Arjan Narbad, BSc, PhD, Ngozi Franslem-Elumogo, MBBS, DTM&H, FRCPath 2020-09-16
CovEx: Recovery of Exertion Ability Following COVID-19 Infection in Military Staff Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Direction Centrale du Service de Sante des Armees France 2020-09-30 2023-03-31 2020-COVID19-30, CovEx, NCT04548505 Phase Not Applicable Not yet recruiting 1 30 Months 100 Alexandra MALGOYRE, MD, PhD 2020-09-16
A Randomized, Controlled, Feasibility Study of Emotional Well-being of Adolescents Undergoing a Mindfulness Training During COVID-19 Coronavirus disease 19 infection Training for Awareness, Resilience, and Action (TARA) alone Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs) University of California San Francisco US 2019-10-18 2020-05-20 19-29083 (B), NCT04548544 Phase Not Applicable Completed 1 7 Months 21 Olga Tymofiyeva, PhD 2020-09-16
Engaging Patients in Colon Cancer Screening Decisions During COVID-19 Colon tumor, Coronavirus disease 19 infection Shared Decision Making alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Massachusetts General Hospital Patient Centered Outcome Research Institute US 2020-09-10 2021-05-30 2020P001579-2, NCT04548531 Phase Not Applicable Not yet recruiting 1 8 Months 800 Karen Sepucha, PhD, Lauren Leavitt, MA 2020-09-16
Telerehabilitation in Oncology Patients Cancer, Coronavirus disease 19 infection Therapeutic Exercise and Education alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Malaga Spain 2020-07-01 2020-12-31 NCT04547634, TELECLUB_CAM Phase Not Applicable Recruiting 1 6 Months 30 Dr. Antonio 2020-09-17
A retrospective, case-series trial to study the variation over time of several biomarkers, demonstrated to be predictors of poor prognostic, in subjects successfully treated with tocilizumab for severe COVID-19: results of a multidisciplinary collaboration Coronavirus disease 19 infection tocilizumab (intravenous), Roche/Chugai alone IL-6 receptor antagonist, IL-6 receptor modulator Hôpital Nord Franche-Comté Phase Not Applicable Status not specified 0 40 2020-09-16
Breath Analysis for SARS-CoV-2 in Infected and Healthy Subjects Coronavirus disease 19 infection Breath analysis alone, Foam cuffed oxygen catheter alone, Multicapillary column coupled ion mobility spectrometry alone, Nasal air sampling alone, PCR alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Klinikum Bayreuth Klinik und Institut für Nuklearmedizin Germany 2020-09-14 2021-04-30 IMS COVID-19, NCT04547114 Phase Not Applicable Recruiting 1 7 Months 200 Claus Steppert, MD, Thomas Bollinger, MD 2020-09-16
Awake-Prone Positioning Strategy for Hypoxic Patients With COVID-19 Coronavirus disease 19 infection, Respiratory failure Awake-Prone Positioning Strategy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Atrium Health US 2020-06-14 2020-09-30 06-20-03E, NCT04547283 Phase Not Applicable Recruiting 1 3 Months 40 Stephanie Taylor, MD 2020-09-16
A case-report study evaluating imatinib therapy in patients with CoVID-19 Coronavirus disease 19 infection, Pneumonia imatinib alone Abl tyrosine kinase inhibitor, Bcr protein inhibitor, Kit tyrosine kinase inhibitor, PDGF receptor antagonist, Signal transduction protein inhibitor Female Hospital Universitario de Fuenlabrada Phase Not Applicable Status not specified 0 1 2020-09-16
Safety and Performance Evaluation of Seraph 100 in Treatment of Patients With COVID-19 Coronavirus disease 19 infection, Infectious disease, Multiple organ failure, Respiratory distress syndrome Antibiotic therapy alone, Extracorporal therapy alone, Seraph 100 Microbind Affinity Blood Filter, Exthera Medical alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) ExThera Medical Europe BV ExThera Medical LLC Germany, US, Netherlands 2020-10-15 2021-04-15 CP022, NCT04547257 Phase Not Applicable Not yet recruiting 3 6 Months 42 Herwig Gerlach, Prof., Jens Schirrmacher, PhD, Natascha de Jong 2020-09-17
A clinical study of Carragelose in combination with the ivermectin for prophylaxis against covid-19 infection Coronavirus disease 19 infection inhalation therapy (carragelose, viral pneumonia/COVID-19), Marinomed plus ivermectin Chloride channel modulator Healthy volunteers accepted Marinomed Biotechnologie GmbH Argentina Phase Not Applicable Status not specified 1 229 2020-09-15
A randomized, controlled trial to examine the effectiveness of convalescent plasma in treating children infected with COVID-19 Coronavirus disease 19 infection convalescent plasma alone Childrens Hospital of Philadelphia Phase Not Applicable Planned 0 2020-09-15
pVAC: Safety and Immunogenicity Trial of Multi-peptide Vaccination to Prevent COVID-19 Infection in Adults Coronavirus disease 19 infection Variable regimens including CoVac-1 , Montanide ISA 51 , XS-15 Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Tubingen 2020-09-30 2021-12-20 NCT04546841, P-PVAC-SARS-COV-2, pVAC Phase 1 Clinical Not yet recruiting 0 14 Months 36 Helmut Salih, Prof. MD, Juliane Walz, PD MD 2020-09-16
Effect of wearing N 95 mask along with surgical mask in health care workers in covid era Coronavirus disease 19 infection N95 mask alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Sanjay Gandhi Postgraduate Institute of Medical Sciences India 2020-10-01 CTRI/2020/09/027787 Phase Not Applicable Not yet recruiting 1 50 Dr Ashish Kumar Kannaujia 2020-09-16
AMC19: Ayurvedic Management of Covid 19 patients Coronavirus disease 19 infection Variable regimens including Bharangyadi kashaya , Guduchi paaneeyam , Sudharshanavati , Thaleesadi choornam Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Indian Medicine and Homoeopathy India 2020-10-01 AMC19, CTRI/2020/09/027786 Phase Not Applicable Not yet recruiting 1 60 Dr J Clarence Davy, Dr Ramaraju, Dr Sunil Roy R 2020-09-17
CHILL: Trial of Therapeutic Hypothermia in Patients With ARDS Atelectasis, Coronavirus disease 19 infection, Pulmonary edema, Respiratory distress syndrome Hypothermia alone, Neuromuscular blockade alone, atracurium alone, cisatracurium besilate alone, vecuronium alone Nicotinic acetylcholine receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Maryland Baltimore County KAI Research, United States Department of Defense US 2020-10-01 2024-05-31 CHILL, NCT04545424, W81XWH2010432 Phase 2b Clinical Not yet recruiting 14 44 Months 340 Abhijit Duggal, MD/MSc/MPH, Bhakti Patel, MD, Carl B Shanholtz, MD, Gerarad Criner, MD, Gerard Criner, MD, Jared Greenberg, MD, Jeffrey D Hasday, MD, John Reillt, MD, John Reilly, MD, Jonathan Sevransky, MD, Lioudmila Karnatovskaia, MD, Lioudmilla Karnatovskaia, MD, Luis Cardenas, DO/PhD, Mark Yoder, MD, Matthew Barrett, DO, Michael Baram, MD, Michael L Terrin, MD/MPH, Nathaniel Marchetti, DO, Rachel Scheraga, MD, Richard Oekler, MD/PhD, Robert S Stephens, MD, Robert Walter, MD, Samuel A Tisherman, MD, Sean Forsythe, MD, Sunit Singla, MD, Sunit singla, MD, Whittney Warren, DO 2020-09-16
Case Control study to check the effect of Measles vaccine in prevention of COVID-19 Coronavirus disease 19 infection Measles vaccine alone Healthy volunteers accepted, Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Serum Institute of India Ltd India 2020-09-21 CTRI/2020/09/027785, MV-CCS-01 Phase Not Applicable Not yet recruiting 1 548 Dr Malangori Parande, Dr Nilesh S Gujar, Dr Prasad Kulkarni 2020-09-16
SODACAN: Efficacy of sofosbuvir and daclatasvir in ambulatory patients with coronavirus disease Coronavirus disease 19 infection Sovodak (Fanavaran Rojan Mohaghegh Daru Co) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tehran University of Medical Sciences Iran 2020-09-10 IR.TUMS.DDRI.REC.1399.014, IRCT20200831048568N1, SODACAN Phase 3 Clinical Recruiting 1 2000 Ali Ali Asgari, Shahin Merat 2020-09-16
A trial to evaluate convalescent plasma in children with life-threatening cases of COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome convalescent plasma alone Childrens Hospital of Philadelphia Agency for Healthcare Research and Quality, Alex's Lemonade Stand Foundation, American Academy of Allergy Asthma and Immunology, Cookies for Kids' Cancer, National Cancer Institute, National Institute of Allergy and Infectious Diseases, The Leukemia & Lymphoma Society, Wellcome Trust - Burroughs Wellcome Fund Phase 2 Clinical Status not specified 0 4 2020-09-15
Impact of strutured telephone teleorientation on the health of elderly during the COVID-19 pandemic Coronavirus disease 19 infection Structured Telephony Orientation alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Brazil 2020-08-15 35367520.6.0000.5470, 4.177.093, RBR-35vwq9, U1111-1254-6143 Phase Not Applicable Recruiting 1 300 Gustavo Akerman Augusto 2020-09-22
Effect of Diphenhydramine Compound in COVID-19 Coronavirus disease 19 infection diphenhydramine alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Karaj University of Medical Sciences Iran 2020-08-22 IR.ABZUMS.REC.1399.079, IRCT20200504047298N3 Phase 3 Clinical Recruiting 1 120 Mohammad Noorisepehr, Zeinab Siami 2020-09-16
External Ocular Manifestations Among Patients Diagnosed with Coronavirus Disease 2019 (COVID-19) in a Referral Center in the Philippines Coronavirus disease 19 infection Philippine General Hospital Philippines 2020-05-01 2021-01-01 PHRR200911-002933 Phase Not Applicable Recruiting 1 8 Months 72 Alyssa Louise Basisto Pejana, Aramis B. Torrefranca Jr., MD, Ma. Dominga Padilla, MD 2020-09-15
Symptoms and Wellbeing of People Infected With Covid-19 Virus in Iceland Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Landspitali University Hospital Iceland 2020-07-01 2020-09-01 LSH-20-002, NCT04546191 Phase Not Applicable Completed 1 2 Months 1580 Brynja Ingadottir, PhD, Helga Jonsdottir 2020-09-17
Inactivated vaccine, COVID-19 Coronavirus disease 19 infection National Institutes of Health Malaysia 2020-09-14 2022-06-30 55005, NMRR-20-1956-55005 Phase Not Applicable Status not specified 1 21 Months Dr ROZAINANEE MOHD ZAIN 2020-09-15
A case-report study presented with COVID-19 through 18F-FDG PET/CT in an asymptomatic patient Coronavirus disease 19 infection 18F-FDG alone, PET/CT alone, azithromycin alone, levofloxacin alone, lopinavir + ritonavir alone, low-molecular-weight heparin alone DNA gyrase inhibitor, HIV protease inhibitor, Topoisomerase IV inhibitor Male Universita Degli Studi G D`Annunzio Chieti Phase Not Applicable Status not specified 0 1 2020-09-14
The effect of dexamethasone in the treatment of high-risk COVID-19 patients Coronavirus disease 19 infection, Hypoxia dexamethasone alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ghoum University of Medical Sciences Qom University of Medical Science Iran 2020-03-29 IR.MUQ.REC.1399.085, IRCT20160118026097N4 Phase 3 Clinical No longer recruiting 1 60 Ehsan sharifipour, Hasan adeli, Jamshid vafaeemanesh, hasan adeli 2020-09-15
Effect of ethanol and DMSO in prophylaxis and treatment of COVID-19 Coronavirus disease 19 infection dimethyl sulfoxide (German Merck) plus ethanol (German Merck) Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shahrood University of Medical Sciences Iran 2020-08-22 IR.SHMU.REC.1399.091, IRCT20200727048217N1 Phase 3 Clinical Recruiting 1 610 Dr. Mohammad Hasan Emamian, Moslem Jafarisani 2020-09-15
Dental practices in COVID-19 Coronavirus disease 19 infection, Dental caries Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shree Krishna Hospital India 2020-09-23 CTRI/2020/09/027782 Phase Not Applicable Not yet recruiting 1 1600 Aalap Prajapati 2020-09-15
A prospective, randomized, double-blind, placebo-controlled clinical study to evaluate the efficacy and safety of ES-16001 as an adjunct to standard of care treatment on mild to moderate COVID-19 positive subjects undergoing treatment for COVID-19 in Hospital Quarantine (Dedicated Covid Health Centre) Coronavirus disease 19 infection ES-16001 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) GENECELL CO LTD India 2020-09-19 CTRI/2020/09/027775 Phase 2 Clinical Not yet recruiting 2 60 Dr Madhu MS, DrJang Yul Kwak, Subham Dutta 2020-09-16
Views regarding dental facilities and the manner in which patients wants to use dental facilities during COVID 19 in a hospital setting Coronavirus disease 19 infection, Tooth disease Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Medical Sciences India 2022-09-22 CTRI/2020/09/027769 Phase Not Applicable Not yet recruiting 1 375 Harsh Priya 2020-09-16
A clinical trial of SPOR-COV for the preventive treatment for COVID-19 Coronavirus disease 19 infection SPOR-COV alone Destiny Pharma Ltd, SporeGen Ltd Technology Strategy Board Phase Not Applicable Planned 0 2020-09-17
A study that demonstrates performance of the BD Veritor System for Rapid Detection of SARS-CoV-2 Assay was equivalent to that of the Quidel Sofia 2 SARS Antigen Fluorescent Immunoassay (AFI) Coronavirus disease 19 infection BD Veritor System alone, Quidel Sofia 2 SARS Antigen Fluorescent Immunoassay alone BD Technologies Phase Not Applicable Status not specified 0 361 2020-09-14
A study to assess use of angiotensin converting enzyme inhibitors (ACE-I)/angiotensin receptor blockers (ARBs) in managing serious clinical symptoms in COVID-19 patients Coronavirus disease 19 infection angiotensin converting enzyme inhibitors (ACE-I) alone, angiotensin receptor blockers (ARBs) alone African Ancestry Berg Pharma LLC University of Oxford, Virginia Commonwealth University Phase Not Applicable Status not specified 0 2020-09-14
A diagnostic test to assess SARS-CoV-2 viral proteins that determines which COVID-19 patients are most likely to become critically ill Coronavirus disease 19 infection Single Molecule Array (Simoa) SARS-CoV-2 antigen test alone American Association for Clinical Chemistry US Phase Not Applicable Status not specified 1 64 David R. Walt, PhD 2020-09-14
CHARTER-MT: Nebulized Heparin in Patients With Severe COVID-19 Coronavirus disease 19 infection, Hypoxia, Respiratory disease Aerogen Solo vibrating mesh nebulizer (Aerogen) alone, invasive mechanical ventilation alone, standard care alone, unfractionated heparin alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The Australian National University UK, Ireland, US, Australia, Spain 2020-10-31 2022-06-30 CHARTER META-TRIAL, CHARTER-MT, NCT04545541 Phase 2/Phase 3 Clinical Not yet recruiting 5 20 Months 202 Frank MP van Haren, MD, PhD, Frank van Haren 2020-09-15
ABC19 study: Outpatient treatment of COVID-19: Impact of comorbidities on hospital admissions and other treatment decisions Coronavirus disease 19 infection Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Germany 2020-09-20 ABC19 study, Aktenzeichen: E-01-20200804, DRKS00023014 Phase Not Applicable Not yet recruiting 2 500 Philipp Jaehn 2020-09-15
A Study to Evaluate the Safety, Tolerability and Immunogenicity of UB-612 COVID-19 Vaccine Coronavirus disease 19 infection UB-612 alone COVID19 Spike glycoprotein modulator, HLA class I antigen modulator, HLA class II antigen modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Covaxx Taiwan 2020-09-01 2021-08-31 NCT04545749, V-122 Phase 1 Clinical Recruiting 1 12 Months 60 Chang-Yi Wang, Ph.D., Joanna Hung, Kao-Pin Hwang, M.D., Ph.D, Kao-Pin Hwang, M.D., Ph.D., Po-Chang Lin, M.D., Wen-Yuan Lin, M.D., Ph.D. 2020-09-16
A compassionate use program to evaluate CYNK-001 for the treatment of patients with severe COVID-19 and on ventilator support Coronavirus disease 19 infection CYNK-001 alone Celularity Inc US Phase Not Applicable Status not specified 1 2020-09-14
SISPIG: Assessment of effect of steam inhalation, saline gargling and povidone iodine gargling on reduction of symptoms and prevention of spread of COVID 19 Coronavirus disease 19 infection povidone iodine alone, povidone iodine gargling alone, saline gargling alone, steam inhalation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bangalore Medical College and Research Institute India 2020-09-16 CTRI/2020/09/027687, SISPIG Phase Not Applicable Not yet recruiting 1 80 Dr shobha 2020-09-14
To determine whether diabetes in COVID-19 patients is associated with more complications Coronavirus disease 19 infection, Diabetes mellitus Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gujarat Cancer Society Medical college hospital and research centre India 2020-09-20 CTRI/2020/09/027686 Phase Not Applicable Not yet recruiting 1 100 Dr Shams Kanuga 2020-09-14
Clinical Study to Investigate Safety and Efficacy of ImmunoSEB and ProbioSEB Coronavirus disease 19 infection ImmunoSEB plus ProbioSEB CSC3 Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Chirayu Medical College and Hospital Advanced Enzymes Technologies Ltd India 2020-09-16 CTRI/2020/09/027685, PROCLIN_COVID-005_Version 1 Phase Not Applicable Not yet recruiting 1 40 Dr Rohit Parate 2020-09-14
Protective effect of re-vaccination with BCG against COVID-19 in healthcare workers – A pilot study Coronavirus disease 19 infection BCG alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) SGT University Indian Council of Medical Research India 2020-09-15 CTRI/2020/09/027684 Phase 3 Clinical Not yet recruiting 1 400 Dr Dharampal Singh Sudan 2020-09-14
Impact of COVID-19 pandemic era on the outcome, morbidity, and mortality of Acute Care Surgery patients Coronavirus disease 19 infection Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mahidol University Thailand 2020-07-18 TCTR20200901001 Phase Not Applicable Completed 1 61 Chonlada Krutsri 2020-09-14
Role of heat killed Mycobacterium w (Sepsivac) in coronavirus disease 2019 (COVID-19) Coronavirus disease 19 infection Mycobacterium w suspension alone, standard therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cadila Pharmaceuticals Ltd India 2020-09-15 CTRI/2020/09/027741 Phase Not Applicable Not yet recruiting 1 50 Dr Dharampal Singh Sudan 2020-09-14
Preventive Study among COVID 19 frontline warriors and their families Coronavirus disease 19 infection Variable regimens including Anu taila , Ayush Kwath , Chyavanprash , Samsamani vati Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) India 2020-09-15 CTRI/2020/09/027661 Phase Not Applicable Not yet recruiting 1 3000 Dr Krishna Rao S, Dr M MRao 2020-09-14
Testing efficacy of Homoeopathic Medicine Camphora 1000 C as an immune booster, reducing the incidence of coronavirus infection Coronavirus disease 19 infection Camphora 1000 C alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) India 2020-09-18 CTRI/2020/09/027688, MHC/CT/19-20/019 Phase 2/Phase 3 Clinical Not yet recruiting 1 4000 Dr Govindarajan Sankaran, Dr Meghna Shah, Dr Rajendra Shrimali 2020-09-14
SALIVA: Testing Saliva for SARS-CoV-2 Coronavirus disease 19 infection nasopharyngeal swabs alone, saliva/sputum testing alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Asian Healthcare Foundation India 2020-09-07 CTRI/2020/09/027597, SALIVA Phase Not Applicable Not yet recruiting 1 100 Dr D Nageshwar Reddy, Dr M Sasikala, Dr Sarala Kumari 2020-09-14
SH2020.COV01: Improving real-time COVID-19 monitoring through smartphone voice analysis Coronavirus disease 19 infection smartphone voice analysis alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Sonde Health India 2020-09-17 CTRI/2020/09/027691, SH2020.COV01, VocoQuest01 version 1.0 Phase Not Applicable Not yet recruiting 1 350 Dr Bharat Purandare, Dr Sharvari Rangnekar, Ms Ulka Gaikwad, Nutan Jadhav 2020-09-15
Satisfaction of medical students with online learning Coronavirus disease 19 infection online learning alone Newborn Infants (up to 5 months) Postgraduate Institute of Medical Education and Research India 2020-09-20 CTRI/2020/09/027719 Phase Not Applicable Not yet recruiting 1 500 Dr Nafisha Yasmin, Dr Saikat Kumar Dalui 2020-09-14
DeCOPO: Effect of Prone Positioning Combined With High Flow Oxygen Therapy on Oxygenation During Acute Respiratory Failure Due to COVID-19 Coronavirus disease 19 infection, Respiratory failure high flow oxygen therapy alone, prone positionning (PP) alone, supine position (SP) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital St. Joseph, Marseille, France 2020-09-30 2021-04-30 2020-04-03, DeCOPO, NCT04543760 Phase Not Applicable Not yet recruiting 0 7 Months 18 2020-09-15
COVID-2019 Testing and Vaccination Among African American and Latinx Public Housing Residents Coronavirus disease 19 infection increasing willingness and uptake of COVID-19 testing and vaccination alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), African Ancestry Charles Drew University of Medicine and Science US 2020-12-01 2022-11-30 COVID19TESTINGVACC, NCT04542395 Phase Not Applicable Not yet recruiting 1 24 Months 310 Mohsen Bazargan, PhD, Sharon Cobb, PhD 2020-09-14
COVID-19 Risk Reduction Among African American Parishioners Coronavirus disease 19 infection change in knowledge, motivation, skills, resources alone Healthy volunteers accepted, Aged Adults (65-79 yrs), Elderly Adults (80 and over) Charles Drew University of Medicine and Science US 2020-10-01 2021-09-30 COVID19CHURCH, NCT04542343 Phase Not Applicable Not yet recruiting 1 12 Months 265 Mohsen Bazargan, PhD, Sharon Cobb, PhD 2020-09-15
XPHI-COVID19: Moral Judgements and Choices of Caregivers in the Time of COVID-19 Pandemic Coronavirus disease 19 infection choices and judgements alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Caen University Hospital University of Geneva Switzerland 2020-09-03 2021-08-02 1474, NCT04542122, XPHI-COVID19 Phase Not Applicable Not yet recruiting 1 11 Months 500 Clement GAKUBA, MD PhD, Florian COVA, PhD 2020-09-14
COVID-19 in a Single Large UK Rheumatology Center and Impact on QOL Coronavirus disease 19 infection, Rheumatoid arthritis questionnaire alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The Royal Wolverhampton Hospitals NHS Trust UK 2020-10-31 2021-10-31 2020COV113, NCT04542031 Phase Not Applicable Not yet recruiting 1 12 Months 7911 James Bateman, Natasha Cleaton 2020-09-17
eWrite: Writing Activities and Emotions Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression positive psychology activities alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Pittsburgh US 2020-09-30 2021-08-01 NCT04539756, STUDY20060287, eWrite Phase Not Applicable Not yet recruiting 1 10 Months 250 Caitlin M DuPont, MS, Peter J Gianaros, PhD 2020-09-15
Mortality score development and costing studies among COVID patients Coronavirus disease 19 infection Seberang Jaya Hospital Malaysia 2020-11-29 2021-11-29 56362, NMRR-20-1918-56362 Phase Not Applicable Status not specified 1 12 Months DR. MONICA A/P DANIAL 2020-09-15
PLC: Managing a Dedicated Quarantine Center for COVID-19 Healthcare Workers of Putrajaya Hospital and their Satisfaction Rate Coronavirus disease 19 infection Putrajaya Hospital Malaysia 2020-09-14 2020-09-30 56376, NMRR-20-1936-56376, PLC Phase Not Applicable Status not specified 1 Dr MUHD SIV AZHAR MERICAN BIN ABDULLAH 2020-09-14
Satisfaction among VAS patients in HRPB Coronavirus disease 19 infection value-added services alone Hospital Raja Permaisuri Bainun Malaysia 2020-10-01 2021-03-31 56243, NMRR-20-1933-56243 Phase Not Applicable Status not specified 1 6 Months Chang Chee Tao, Miss Chew Lan Sim 2020-09-14
EpidHPj: Lessons Learnt From An Epidemiological Investigation Of COVID-19 Outbreak Amongst Healthcare Workers In A Major Specialist Hospital In Malaysia Coronavirus disease 19 infection Putrajaya Hospital Malaysia 2020-09-15 2020-09-30 55274, EpidHPj, NMRR-20-1935-55274 Phase Not Applicable Status not specified 1 Dr MUHD SIV AZHAR MERICAN BIN ABDULLAH 2020-09-15
An observational, case report study to determine the management of COVID-19 pneumonia in a kidney transplant recipient with the use of tocilizumab and hydroxychloroquine Coronavirus disease 19 infection, Pneumonia hydroxychloroquine plus tocilizumab University of Modena and Reggio Emilia Phase Not Applicable Status not specified 0 1 2020-09-14
Analysis of the Quality and Quantity of Antibiotic Prescriptions for Bacterial Respiratory Tract Superinfection in Patients Hospitalized in COVID-19 Wards Bacterial respiratory tract infection, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitair Ziekenhuis Brussel Belgium 2020-05-01 2021-03-01 2020-163, NCT04544072 Phase Not Applicable Recruiting 1 10 Months 400 Dora Mss Monteyne, nurse, Johan Dr Van Laethem, MD 2020-09-14
CoviTrem1: TREM-1 Pathway Activation in COVID-19 Coronavirus disease 19 infection blood sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Hospital, Nancy, France Inotrem SA, University Hospital, Limoges France 2020-10-01 2023-04-01 2020PI120, CoviTrem1, NCT04544891 Phase Not Applicable Not yet recruiting 2 30 Months 1000 Bruno Francois, Bruno Francois, MD, Gibot Sebastien 2020-09-14
Readiness Involvement Of Health Care Workers During Crisis Coronavirus disease 19 infection Sultanah Aminah Hospital Malaysia 2020-09-15 2021-02-15 55327, NMRR-20-1904-55327 Phase Not Applicable Status not specified 1 5 Months Puan Shirly Binti Berso 2020-09-15
MACBADCPPIHISM: Measuring anti-microbials consumption before and during Covid-19 pandemic period in hospitals in Selangor, Malaysia Coronavirus disease 19 infection Malaysia 2020-10-01 2022-10-01 56203, MACBADCPPIHISM, NMRR-20-1903-56203 Phase Not Applicable Status not specified 4 24 Months ABDULLAH FAIZ BIN ZAIHAN 2020-09-14
COVID19 and Olfactory Impairment Coronavirus disease 19 infection, Ear disease Universiti Kebangsaan Malaysia Malaysia 2020-09-07 2020-12-31 55310, NMRR-20-1901-55310 Phase Not Applicable Recruiting 1 3 Months DR SALINA BINTI HUSAIN 2020-09-14
Gastrointestinal Manifestations Among Patients With COVID-19 Coronavirus disease 19 infection, Gastrointestinal disease Assiut University Egypt 2020-06-01 2020-09-01 COVID19 AND GUT, NCT04544150 Phase Not Applicable Completed 1 3 Months 220 Ahmed Abu elfatth, Ahmed Mohammed Abu Elfatth 2020-09-14
Seroepidemiological investigation of SARS-CoV-2 infection in health workers working in COVID-19 centers Coronavirus disease 19 infection Seroepidemiological investigation alone Healthy volunteers accepted National Institute of Respiratory Diseases, Mexico Mexico 617/2020 Phase Not Applicable Recruiting 2 6568 Dr. Santiago Ávila 2020-09-14
IL-6 Gene (174G/C) Single Nucleotide Polymorphism as an Indicator of COVID-19 Severity in Egyptian Patients Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia ELISA technique alone, PCR-RFLP technique alone Tanta University Egypt 2020-09-15 2021-01-31 IL6 IN EGYPTIAN COVID PATIENTS, NCT04544033 Phase Not Applicable Recruiting 1 4 Months 120 bsant safwat kasem, master, bsant safwat kasem, principle investigator 2020-09-22
Observational Study of Convalescent Plasma for Treatment of Veterans With COVID-19 Coronavirus disease 19 infection COVID-19 convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) VA Office of Research and Development Mayo Clinic Foundation US 2020-08-07 2022-06-30 2030, CSP #2030, NCT04545047 Phase Not Applicable No longer recruiting 2 22 Months 4000 Nicholas L. Smith, PhD 2020-09-14
COVID-19 Risk From Attending Outpatient Appointments Coronavirus disease 19 infection Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Nottingham University Hospital University Hospital of Wales UK 2020-01-01 2021-01-01 20NS031, NCT04544176 Phase Not Applicable No longer recruiting 1 12 Months 34000 Nikos Evangelou, FRCP, DPhil (Oxon) 2020-09-15
Special Chinese Medicine Out-patient Program for Discharged COVID-19 Patients Coronavirus disease 19 infection, Lung disease, Spleen disease Variable regimens including American ginseng , Amomum villosum , Chenpi , Codonopsis , French Pinellia , Huoxiang , Licorice , Ophiopogonis , Poria , Schisandra , Stir-fried Atractylodes , Sunburn Astragalus , gypsum , light bamboo leaf , mulberry leaf , radix salviae , raw liquorice , reed root , salviae miltiorrhiza Hong Kong Baptist University Chinese University of Hong Kong, The University of Hong Kong Hong Kong 2020-09-07 2021-12-31 HA COVID-19, NCT04544605 Phase Not Applicable Recruiting 1 15 Months 150 Ching LIONG, PhD, Linda Zhong, PhD, Yi Bin FENG, PhD, ZhaoXiang Bian, Zhaoxiang Bian, PhD 2020-09-16
The efficacy and safety of ambroxol hydrochloride in the treatment of novel coronavirus pneumonia (COVID-19): a retrospective medical based study Coronavirus disease 19 infection ambroxol hydrochloride alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Zhangnan Hospital Boehringer Ingelheim International GmbH China 2020-05-01 2022-05-31 ChiCTR2000038160 Phase 2 Clinical Recruiting 1 25 Months 1200 Hong Cheng, Kun Yang 2020-09-14
CLOVIS: Pediatric Intensive Care and COVID-19 Coronavirus disease 19 infection, Lung embolism, Respiratory distress syndrome, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopital de Bicetre France 2020-03-26 2021-06-01 CLOVIS, NCT04544878, PS-PICRN--20001 Phase Not Applicable Recruiting 1 14 Months 100 Clemence Marais, MD, MSc, Jordi Miatello, MD, MSc, Pierre Tissieres, MD, DSc 2020-09-14
A Phase I Clinical Trial of Influenza virus Vector COVID-19 Vaccine for intranasal Spray (DelNS1-2019-nCoV-RBD-OPT1) Coronavirus disease 19 infection DelNS1-2019-nCoV-RBD-OPT1 alone, Influenza virus Vector COVID-19 Vaccine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Jiangsu Province Centers for Disease Control and Prevention Beijing Wantai Biological Pharmacy Enterprise Co Ltd China 2020-09-01 2021-10-01 ChiCTR2000037782, DelNS1-2019-nCoV-RBD-OPT1 Phase 1 Clinical Not yet recruiting 1 13 Months 60 Fengcai Zhu, Xiangzhong Ye 2020-09-15
A phase I/II clinical study to asses virus-like particle (VLP) vaccine in the treatment of subjects with COVID-19 infection Coronavirus disease 19 infection SARS-CoV-2 vaccine (virus like particle-based vaccine, SpyCatcher/SpyTag, COVID-19), SpyBiotech/Serum Institute of India alone COVID19 Spike glycoprotein modulator Serum Institute of India Ltd SpyBiotech Limited Australia Phase 1/Phase 2 Clinical Recruiting 1 2020-09-22
A multicenter, phase I/II clinical study to assess the the safety and efficacy of AZD-1222 in the treatment of patients with COVID-19 infection Coronavirus disease 19 infection AZD-1222 alone COVID19 Spike glycoprotein modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) AstraZeneca plc Japan 2020-09-08 Phase 1/Phase 2 Clinical Recruiting 1 250 2020-09-22
Trial of Famotidine and N-Acetyl Cysteine for Outpatients With COVID-19 Coronavirus disease 19 infection N-acetyl cysteine alone, N-acetyl cysteine plus famotidine Histamine H2 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Prisma Health-Upstate Clemson University 2020-09-30 2021-08-31 NCT04545008, PRO00100394 Phase 1 Clinical Not yet recruiting 0 11 Months 42 John J O'Connell, M.D., Julie Martin, DNP 2020-09-14
A phase II/III study to evaluate RHB-107 in an outpatient setting in patients with COVID-19 Coronavirus disease 19 infection upamostat alone Serine protease inhibitor, Trypsin 1 inhibitor, Trypsin 2 inhibitor, Trypsin 3 inhibitor, Urokinase plasminogen activator inhibitor RedHill Biopharma Ltd US Phase 2/Phase 3 Clinical Planned 1 2020-09-11
A retrospective, cohort study to evaluate whether ibuprofen administration to patients with COVID-19 was associated with worse clinical outcomes, compared with paracetamol or no antipyretic Coronavirus disease 19 infection ibuprofen alone, paracetamol alone Israel Phase Not Applicable Status not specified 1 403 2020-09-14
DEXA-REFINE: Efficacy of Dexamethasone in Patients With Acute Hypoxemic Respiratory Failure Caused by Infections Adult respiratory distress syndrome, Coronavirus disease 19 infection, Hypoxia, Respiratory failure, Viral pneumonia dexamethasone alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dr. Negrin University Hospital Centro de Investigación Biomédica en Red, Li Ka Shing Knowledge Institute Spain 2020-10-07 2023-12-30 DEXA-REFINE, ICI20-00062, NCT04545242 Phase 4 Clinical Not yet recruiting 39 38 Months 980 Alberto Martínez-Ruiz, MD, Alec Tallet, MD, Alfonso Ambrós, MD, Angel Candela, MD, Anxela Vidal, MD, Arthur Slutsky, MD, Carlos Ferrando, MD, Carlos García-Palenciano, MD, Carmen Martin-Delgado, MD, Carmen Martín, MD, Chanel Martínez, MD, Concepción Tarancón, MD, César Aldecoa, MD, César Calvo, MD, Dacil Parrilla, MD, David Pestaña, MD, Demetrio Carriedo, MD, Domingo Martínez, MD, Elena González, MD, Eleuterio Merayo, MD, Emilio Maseda, MD, Federico Gordo, MD, Fernando Mosteiro, MD, Fernando Suarez-Sipmann, MD, Francisco Alba, MD, Francisco J Díaz, MD, Gerardo Aguilar, MD, Gonzalo Tamayo, MD, Isabel Murcia, MD, Isidro Prieto, MD, Javier Fernández, MD, Jesús Rico, MD, Jesús Villar, MD, Josep Trenado, MD, José A Carbonell, MD, José A Lorente, MD, José Ferreres, MD, José I Gómez-Herreras, MD, José M Añón, MD, Juan A Soler, MD, Juan C Figueira, MD, Juan M Mora-Ordoñez, MD, Julián Álvarez, MD, Lidia Pita-García, MD, Lorena Fernández, MD, Manuel Castallá, Marina Varela, MD, Mario Chico, MD, Mario Lorenzo-López, MD, María Hernández, MD, María L Blasco, MD, María M Fernández, MD, Miguel A Romera, MD, Pablo Blanco-Schweizer, MD, Pablo Monedero, MD, Pablo Serna-Grande, MD, Paloma González-Arenas, MD, Pedro Castro, MD, Piedad Martinez-Gil, MD, Pilar Diaz-Parada, MD, Raquel Herrero, MD, Raquel Montiel, MD, Ricard Mellado-Artigas, MD, Rosario Solano, MD, Ruth Corpas, MD, Silvia Cortés-Díaz, MD, Tomás Muñoz, MD, Trinidad Puente, MD, Ángela Prado-Mira, MD 2020-09-18
A phase IIb/III clinical trial of protein subunit vaccine (molecular clamp, COVID-19), University of Queensland for the potential prevention of COVID-19 infection Coronavirus disease 19 infection protein subunit vaccine (molecular clamp, COVID-19), University of Queensland alone COVID19 Spike glycoprotein modulator CSL Ltd 2020-12-31 Phase 2/Phase 3 Clinical Planned 0 2020-09-11
Observational, Open Study of Polyoxidonium in Hospitalized Patients With COVID-19 Coronavirus disease 19 infection, Tachypnea Polyoxidonium alone, complex treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) NPO Petrovax Pharm LLC Russian Federation 2020-04-09 2020-10-31 COVID_V_1.0, NCT04542226 Phase Not Applicable No longer recruiting 1 6 Months 81 2020-09-15
Reszinate: Can SARS-CoV-2 Viral Load and COVID-19 Disease Severity be Reduced by Resveratrol-assisted Zinc Therapy Coronavirus disease 19 infection Zinc Picolinate plus resveratrol Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Swedish Medical Center (Seattle) US 2020-09-30 2022-06-30 NCT04542993, Reszinate, SHS KAPH NSWE 20090 Phase 2 Clinical Not yet recruiting 1 21 Months 60 Cancer Regulatory, Cancer Research, Chris Nunn, MD 2020-09-14
Efficacy of mouth-rinses in reducing SARS CoV-2 viral load in the saliva of COVID-19 positive patients Coronavirus disease 19 infection cetylpyridinium chloride alone, chlorhexidine gluconate alone, povidone-iodine alone National Dental Centre Singapore Singapore 2020-04-15 2021-06-16 329/2020, ISRCTN95933274 Phase 2 Clinical Recruiting 1 14 Months 68 Dr Jaya Seneviratne 2020-09-15
Using BCG to Protect Senior Citizens During the COVID-19 Pandemic Coronavirus disease 19 infection BCG vaccine alone Healthy volunteers accepted, Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bandim Health Project Odense Municipality, Odense Patient Explorative data Network (OPEN), Odense Patient data Explorative Network, Odense University Hospital Guinea-Bissau 2020-09-11 2022-03-31 BCG-DENMARK-SENIOR, NCT04542330 Phase 3 Clinical Not yet recruiting 1 18 Months 1900 Anne Marie Rosendahl Madsen, MD, Christine Stabell Benn, DMSc 2020-09-14
Qualitative Evaluation of Tear Fluid and Blood for Auto Antibodies Produced in Response to COVID-19 Coronavirus disease 19 infection ELISA assay alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) 2020-09-15 2020-12-31 CVDTRS001, NCT04542980 Phase Not Applicable Not yet recruiting 0 3 Months 200 Anna Daily, PhD 2020-09-14
OMC-KTR: Optimized Management of Covid-19 Positive Kidney Transplant Recipients: Single-Center Experience From the Middle East Coronavirus disease 19 infection, Kidney transplantation Ministry of Health in Kuwait Kuwait 2020-03-01 2020-08-31 2020/1481, NCT04542954, OMC-KTR Phase Not Applicable Completed 1 6 Months 104 2020-09-12
NINTECOR: Nintedanib for the Treatment of SARS-Cov-2 Induced Pulmonary Fibrosis Coronavirus disease 19 infection, Pulmonary fibrosis nintedanib alone CSF-1 antagonist, FGF receptor antagonist, FGF1 receptor antagonist, FGF2 receptor antagonist, FGF3 receptor antagonist, Flt3 tyrosine kinase inhibitor, Lck tyrosine kinase inhibitor, Lyn tyrosine kinase inhibitor, PDGF receptor alpha antagonist, PDGF receptor antagonist, PDGF receptor beta antagonist, Src tyrosine kinase inhibitor, VEGF receptor antagonist, VEGF-1 receptor antagonist, VEGF-2 receptor antagonist, VEGF-3 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris Boehringer Ingelheim International GmbH 2020-09-30 2021-12-31 APHP200527, NCT04541680, NINTECOR Phase 3 Clinical Not yet recruiting 0 15 Months 250 Bruno Crestani, MD,PHD 2020-09-21
The Building Educators’ Skills in Adolescent Mental Health (BEAM) study: A Cluster Randomized-controlled Trial of an Adolescent Mental Health Training Program for Secondary School Educators Coronavirus disease 19 infection BEAM training program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of New South Wales Australia 2020-08-14 2021-02-22 ACTRN12620000876998, U1111-1253-3176 Phase Not Applicable Recruiting 1 6 Months 234 Dr Belinda Parker 2020-09-15
PneumoCoV-Ambu: Evaluation of the Safety and Outcomes of Outpatient Management With Mild to Moderate COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopitaux Universitaires De Geneve Switzerland 2020-04-02 2020-06-30 CCER2020-01518, NCT04542044, PneumoCoV-Ambu Phase Not Applicable Completed 1 2 Months 40 Chevallier-Lugon Chloe 2020-09-11
CoMaND: A Collaborative Maternity and Newborn Dashboard for the COVID-19 Pandemic Coronavirus disease 19 infection Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) University of Melbourne Australia 2020-09-17 ACTRN12620000878976, CoMaND Phase Not Applicable Not yet recruiting 3 180000 A/Prof Lisa Hui 2020-09-15
The effectiveness of Online Communities for (expectant) mothers with stress and worries about COVID-19 Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression Online Communities alone Female The Netherlands Organisation for Health Research and Development Netherlands 2020-09-04 2021-09-04 2020-CDE-12134, NL8842 Phase Not Applicable Recruiting 1 12 Months 50 Eva Potharst 2020-09-14
Workforce Sero-surveillance to Track Long-term Modifications to COVID-19 Exposure Due to Factors in the Built Environment Coronavirus disease 19 infection Antibody testing alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Northwell Health Inc US 2021-01-01 2022-12-31 20-0668, NCT04542200 Phase Not Applicable Recruiting 2 24 Months 70812 Grace Sembajwe, ScD 2020-09-11
Efficacy and Safety of Guduchi Ghan Vati in the Management of Asymptomatic COVID-19 Infection Coronavirus disease 19 infection Guduchi Ghan Vati extract alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Aarogyam UK Dr.S R.Rajasthan Ayurved University Jodhpur India 2020-05-01 2020-08-18 AYU/DSSR/03, NCT04542876 Phase Not Applicable Completed 1 3 Months 46 Abhimanyu Kumar, Neha Sharma 2020-09-14
Lung Ultrasound Implementation in the Management of Patients Hospitalized With COVID-19 Coronavirus disease 19 infection lung ultrasound alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Colorado US 2020-07-01 2021-12-01 20-0781, NCT04542421 Phase Not Applicable Recruiting 1 17 Months 90 Anna Maw, MD 2020-09-12
COVIDIT: Assessment of Safety and Efficacy of CCP Coronavirus disease 19 infection COVID-19 convalescent plasma alone, COVID-19 standard of care therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Makerere University Joint Clinical Research Center, Mulago Hospital Uganda 2020-06-16 2020-10-31 CCP, COVIDIT, NCT04542941 Phase 2 Clinical No longer recruiting 1 4 Months 136 2020-09-12
A Remote, Decentralized, Opioid Use Disorder Study to Evaluate Patient Engagement With a Game-Based Digital Therapeutic Coronavirus disease 19 infection, Opiate dependence PEAR-008 therapeutic mobile application (Pear Therapeutics Inc) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Pear Therapeutics Inc National Institute on Drug Abuse, Research Foundation for Mental Hygiene Inc US 2020-09-30 2021-07-31 NCT04542642, PEAR-008-101, R44DA042652 Phase Not Applicable Not yet recruiting 2 10 Months 130 Aimee Campbell, PhD, Angelo Cruz, Christina Brezing, Hilary Luderer, Lisa Chiodo, PhD 2020-09-14
Use of mesenchymal cells for the treatment of patients with severe acute respiratory syndrome caused by SARS-CoV-2 Coronavirus disease 19 infection, Respiratory distress syndrome mesenchymal cells alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Pontifical Catholic University of Paraná Conselho Nacional de Desenvolvimento Cientifico e Tecnologico - CNPq Brazil 2020-06-10 30833820.8.0000.0020, 4.041.850, RBR-3fz9yr, U1111-1254-9819 Phase 2 Clinical No longer recruiting 1 15 Carmen Kuniyoshi Rebelatto, Paulo Roberto Brofman 2020-09-11
PC-COVID-HCM: Study on the Safety and Efficacy of Convalescent Plasma in Patients With Severe COVID-19 Disease Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia convalescent plasma alone, standard care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Central Militar Mexico 2020-06-23 2020-09-30 047/2020, NCT04542967, PC-COVID-HCM Phase 2 Clinical Recruiting 1 3 Months 150 Blanca E Cid Dominguez, Blanca E Cid Dominguez, MD, Carlos M Muñoz Arce, MD, Carmen G Torres Alarcón, MD, Carmen G Torres, MD, Cesar R Cañete Ibáñez, MD, Deniria A Rugerio Trujillo, MD, Gabriela Ramírez Galindo, MD, Guadalupe Maza de la Torre, MD, Irving I Morales Pogoda, MD, Jose L Hernandez Perdomo, MD, Liliana Bonola Gallardo, MD, Max J Martínez Utrera, MD, Miguel A Sandoval López, MD, Miriam S Ramírez Valdez, MD 2020-09-11
HERO-19: Hamburg Edoxaban for Anticoagulation in COVID-19 Study Coronavirus disease 19 infection LMWH plus edoxaban Factor Xa antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitätsklinikum Hamburg-Eppendorf Germany 2020-09-01 2021-09-30 HERO-19, HERO-19, NCT04542408 Phase 3 Clinical Not yet recruiting 8 13 Months 172 Bode, MD, Christian Karagiannidis, MD, Hans-Jörg Busch, Hartmut Schmidt, MD, Mahir Karakas, MD, Schäfer, MD, Stefan Kluge, MD, Tobias Lahmer, Tobias Welte, MD 2020-09-11
The Impact of Premorbid Illnesses on the Risk of ICU Admission and Short-term Outcome Adult respiratory distress syndrome, Coronavirus disease 19 infection, Sepsis, Septic shock Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Uppsala University Center for Clinical Research Dalarna Sweden 2018-04-11 2020-10-04 NCT04542538, U1111-1257-2830 Phase Not Applicable No longer recruiting 1 29 Months 15000 Miklos Lipcsey, PhD 2020-09-11
Covid19DPP4i: Dipeptidyl Peptidase-4 Inhibitor (DPP4i) for the Control of Hyperglycemia in Patients With COVID-19 Coronavirus disease 19 infection, Hyperglycemia insulin plus linagliptin Dipeptidyl peptidase IV inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hospital Regional de Alta Especialidad del Bajio Mexico 2020-08-01 2020-09-30 CEI-22-2020, Covid19DPP4i, NCT04542213 Phase 3 Clinical Recruiting 1 2 Months 28 Liz Jovanna Martinez, MD, Miguel A Garcia, MD, Rodolfo Guardado, PhD 2020-09-14
PANCOLIN: Persistence of Neutralizing Antibodies 6 and 12 Months After a Covid-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Grenoble France 2020-09-08 2021-12-31 ESSAICLINIQUE_PANCOLIN, NCT04543006, PANCOLIN Phase Not Applicable Not yet recruiting 1 15 Months 170 Olivier Epaulard, MD,PhD 2020-09-16
ChoCO: Risk factors for necrotic cholecystitis during Covid-19 pandemic: the ChoCO WSES prospective, multicenter, observational study Adult respiratory distress syndrome, Cholecystitis, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Poissy-Saint Germain Hospital France 2020-10-31 2021-09-30 06012020, ChoCO, NCT04542512 Phase Not Applicable Not yet recruiting 1 11 Months 800 Belinda De Simone, Elie Chouillard 2020-09-14
To Evaluate Safety, Tolerability and Pharmacodynamics of DWRX-2003 Against COVID-19 (in Philippines) Coronavirus disease 19 infection repositioned niclosamide (refractory lung disease/COVID-19), Daewoong Pharmaceutical/Institut Pasteur Korea alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Daewoong Pharmaceutical Co Ltd Philippines 2020-10-06 2021-01-29 DW_DWJ1516101_PHILLIPPHINES, NCT04541485 Phase 1 Clinical Not yet recruiting 1 3 Months 40 2020-09-11
A clinicla trial of Nomovid Nasal Spray as prophylaxis against COVID-19 Coronavirus disease 19 infection Nomovid Nasal Spray alone Parnell Pharmaceuticals Phase Not Applicable Planned 0 2020-09-10
The effect of confinement on the mental health of individuals during the COVID-19 pandemic: an online survey Anxiety disorder, Coronavirus disease 19 infection, Depression, Eating disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hotel Dieu de France Hospital Lebanon 2020-04-14 2020-05-15 HDF 1632, LBCTR2020043459 Phase Not Applicable Not yet recruiting 1 1 Month 500 Ghassan Sleilaty, Ramez Dagher, Rami Bou Khalil, Sami Richa 2020-09-14
A study to assess safety of vaccine (oral COVID-19) VaxForm for the prevention of covid-19 Coronavirus disease 19 infection CoV2-OGEN1 alone COVID19 Spike glycoprotein inhibitor VaxForm LLC 2021-01-31 Phase 1 Clinical Planned 0 2020-09-17
Niclosamide in COVID-19 Coronavirus disease 19 infection, Viral pneumonia FW-1022 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) First Wave Bio, Inc US, EU 2020-11-01 2021-05-01 FW-COV-003, NCT04542434 Phase 2 Clinical Not yet recruiting 1 6 Months 148 Tony Opipari, M.D. 2020-09-13
COVUSI: Covid-19, Acute Myocardial Infarctions and Strokes in France Coronavirus disease 19 infection, Myocardial infarction, Stroke Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Montpellier France 2020-12-01 2021-06-30 COVUSI, NCT04542083, RECHMPL20_0513 Phase Not Applicable Not yet recruiting 1 7 Months 4000 Grégoire Mercier, PU PH 2020-09-11
Pilot Study to Evaluate the Safety, Tolerability and Efficacy of 5-ALA-Phosphate + SFC in Subjects With COVID-19 Coronavirus disease 19 infection, Respiratory disease 5-aminolevulinic acid phosphate plus sodium ferrous citrate Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Royal College of Surgeons in Ireland - Medical University of Bahrain Bahrain Defense Force Royal Medical Service Hospital Bahrain 2020-09-30 2020-12-31 68 / 02-AUG-2020, NCT04542850 Phase Not Applicable Not yet recruiting 1 3 Months 40 Abdulla Darwish, Dr, Abdullah Darwish, Dr, Abdulrahman Hasan Almadani, Dr, Jalal Abdullah Al-Kahn, Dr, Mariam Murad, Dr 2020-09-14
COVISTRESS - Dental Surgery: Influence of the COVID-19 Pandemic on the STRESS of Dental Surgeons Acute stress disorder, Coronavirus disease 19 infection Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Clermont-Ferrand France 2020-05-01 2020-12-01 2020 COVISTRESS DENTAL SURGERY, COVISTRESS - Dental Surgery, NCT04541472 Phase Not Applicable Recruiting 1 7 Months 1000 Frederic DUTHEIL, Lise LACLAUTRE, Lise Laclautre 2020-09-11
COVID-19-Related Health and Practices Among Dental Hygienists Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) American Dental Association Foundation US 2020-09-30 2021-10-31 ADA20-11, NCT04542915 Phase Not Applicable Not yet recruiting 1 13 Months 5000 Cameron Estrich, Cameron Estrich, MPH, PhD 2020-09-14
Whole-lung low dose radiation therapy (LDRT) in the treatment of severe COVID-19 pneumonia Coronavirus disease 19 infection, Viral pneumonia Low Dose Radiation, 100cGy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Aga Khan University Hospital Kenya 2020-09-15 IERC 111, PACTR202009769021840 Phase Not Applicable Not yet recruiting 1 20 FARROK KARSAN, MANSOOR SALEH, WANGARI SIIKA 2020-09-11
Self-Management Across the Care Continuum Coronavirus disease 19 infection, Spinal cord injury VIP4SCI (Technology-enabled self-management and rehabilitation solution) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Lawson Health Research Institute The Craig H. Neilsen Foundation, The University Health Network Canada 2020-09-01 2021-04-29 115501, NCT04540679 Phase Not Applicable Not yet recruiting 1 7 Months 60 Dalton Wolfe, PhD, Heather Askes, BSc 2020-09-15
Neural Mechanisms of Mindfulness-based Cognitive Therapy (MBCT) for Posttraumatic Stress Disorder (PTSD) - COVID Related Substudy Coronavirus disease 19 infection, Post traumatic stress disorder Mindfulness-Based Cognitive Therapy alone, Muscle Relaxation Therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Michigan National Center for Complementary and Integrative Health US 2020-10-31 2021-12-31 1R61AT009867, HUM00152509-COVID SUBSTUDY, NCT04540939 Phase Not Applicable Not yet recruiting 1 14 Months 60 Anthony King, Ph.D., Jung Park 2020-09-15
VCPM: Virtual Pain Care Management (COVID-19) Coronavirus disease 19 infection, Pain Virtual Chronic Pain Management alone, long-term opioid therapy (LTOT) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) VA Office of Research and Development US 2020-10-01 2021-06-30 C19 20-397, NCT04539821, VCPM Phase Not Applicable Not yet recruiting 2 9 Months 60 Brent A Moore, PhD, Brent Adams Moore, PhD, Joseph W Frank, MD MPH, Samara Zuniga, BA 2020-09-14
COVID-NURSE: The development, testing and evaluation of a COVID-19 fundamental nursing care protocol Coronavirus disease 19 infection nursing care protocol uasge alone, usual care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Exeter University National Institute for Health Research (NIHR) UK 2020-07-20 2021-04-19 COVID-NURSE, ISRCTN13177364, MR/V02776X/1, IRAS 287288, CPMS 46874 Phase Not Applicable Not yet recruiting 2 9 Months 1080 Prof Richards 2020-09-11
Ptsd Associated Covid19 Aong Frontliners at Perak Tengah District Health Coronavirus disease 19 infection, Post traumatic stress disorder Malaysia 2020-09-15 2020-12-15 NMRR-20-1883-55540 Phase Not Applicable Status not specified 1 3 Months Saidatul Solehah bt Mohamad Nor 2020-09-11
Messages sent via WhatsApp to analyze adherence to protection measures in the pandemic Coronavirus disease 19 infection, Coronavirus infection WhatsApp messaging alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Federal University of São Paulo Brazil 2020-09-10 31324820.1.1001.5505, 4,077,371, RBR-2s94rb, U1111-1256-9884 Phase Not Applicable Not yet recruiting 1 200 Juliana de Lima Lopes, Vinicius Lino Souza Neto 2020-09-10
Characterization of Multisystem Inflammatory Syndrome in Children (MIS-C) and Its Relationship to Kawasaki Disease Coronavirus disease 19 infection, Inflammatory disease, Kawasaki disease polymerase chain reaction (PCR) alone Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of California San Diego US 2020-08-01 2021-07-01 CER-1602-34473, NCT04538495 Phase Not Applicable Recruiting 1 11 Months 100 Adriana H Tremoulet, Adriana H Tremoulet, MD, Jane C Burns, Jane C Burns, MD 2020-09-14
Evaluating Impacts of CSS for Veterans and Their Families in Ukraine Coronavirus disease 19 infection, Psychiatric disorder CETA Short Session (CSS) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Johns Hopkins Bloomberg School of Public Health United States Agency for International Development Ukraine 2020-02-28 2021-06-30 9782, NCT04234815 Phase Not Applicable Recruiting 1 16 Months 1387 Judy Bass, PhD, Sergiy Bogdanov, Sergiy Bogdanov, PhD, Tara Russell 2020-09-14
Open, randomized, multicenter, controlled study of the efficacy and safety of the drug CKD-314 (Nafabeltan) in adult patients hospitalized with COVID-19 pneumonia Coronavirus disease 19 infection, Viral pneumonia nafamostat (COVID-19 infection), Institut Pasteur Korea alone Serine protease inhibitor, Transmembrane serine protease 2 inhibitor Chong Kun Dang Pharmaceutical Corp Russian Federation 2020-08-31 2021-05-31 A108_02CVD2014 Phase 2 Clinical Not yet recruiting 24 9 Months 118 2020-09-15
Evaluation of the effectiveness of Nigel-7 capsule and black seed mixture on Corona Coronavirus disease 19 infection Variable regimens including Nigle 7 (Talaye sabze tooba company) , azithromycin , black seed mixture (Talaye sabze tooba company) , naproxen Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bagheiat-allah University of Medical Sciences Iran 2020-11-05 IR.BMSU.REC.1399.038, IRCT20160131026298N6 Phase 2/Phase 3 Clinical Not yet recruiting 1 80 Ahmad Reza Sharifi Olounabadi, Gholamhosein Alishiri 2020-09-11
A phase I clinical study to evaluate the safety and efficacy of AKS-452 in the prevention of COVID-19 infection Coronavirus disease 19 infection AKS-452 alone COVID19 Spike glycoprotein modulator Akston Biosciences Corp TRACER Europe BV Netherlands Phase 1 Clinical Planned 1 2020-09-21
NBT-NM-108 as an Early Treatment of Suspected or Confirmed COVID-19 in Patients With Prediabetes or Type 2 Diabetes Coronavirus disease 19 infection, Diabetes mellitus, Non-insulin dependent diabetes NBT-NM-108 alone, usual care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Rutgers University, University of South Florida US 2020-10-01 2021-03-01 NBTNM10810012020, NCT04540406 Phase 2 Clinical Not yet recruiting 1 5 Months 100 Asa Oxner, MD, Jeffrey Zhao, Liping Zhao, PhD 2020-09-16
Safety and Efficacy of Dapansutrile for Treatment of Moderate COVID-19 Symptoms and Evidence of Early Cytokine Release Syndrome Coronavirus disease 19 infection, Systemic inflammatory response syndrome dapansutrile (oral capsule, inflammation/pain), Olatec Industries alone NACHT LRR PYD domain protein 3 inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Olatec Industries LLC CTI Clinical Trial and Consulting Services US 2020-09-30 2021-02-28 NCT04540120, OLT1177-10 Phase 2 Clinical Recruiting 1 5 Months 80 Clinical Trial Operations 2020-09-21
Impact of a pandemic on visiting students to a foreign country – an in-depth interview Coronavirus disease 19 infection in-depth interview alone Healthy volunteers accepted, Young Adults (18-44 yrs) Manipal Academy of Higher Education China 2020-10-05 CTRI/2020/09/027543 Phase Not Applicable Not yet recruiting 1 17 Dr P Arathi Rao 2020-09-14
COSTA: COVID-19 Phase Ib Study of Safety and Tolerability of Alvelestat Coronavirus disease 19 infection, Respiratory disease alvelestat alone, standard of care alone Leukocyte elastase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mereo BioPharma Group Ltd, University of Alabama at Birmingham US 2020-10-01 2021-09-30 COSTA, IRB-300005845, NCT04539795 Phase 1/Phase 2 Clinical Not yet recruiting 2 12 Months 15 James M Wells, MD, Mark Dransfield, MD, Mark T Dransfield, MD 2020-09-14
REPAVID-19: A phase II/III, randomized study of reparixin in the treatment of patients with severe COVID-19 pneumonia Coronavirus disease 19 infection, Viral pneumonia reparixin alone CXCR1 chemokine antagonist, CXCR2 chemokine antagonist, IL-8 receptor antagonist Dompe Farmaceutici SpA Brazil, US REPAVID-19 Phase 2/Phase 3 Clinical Not yet recruiting 10 159 2020-09-09
AZD-1222 Vaccine for the Prevention of COVID-19 Coronavirus disease 19 infection AZD-1222 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) AstraZeneca plc Covance Inc, IQVIA RDS Pty Ltd Russian Federation 2020-08-26 2021-03-05 D8111C00001, NCT04540393 Phase 3 Clinical Suspended 4 6 Months 100 AstraZeneca Clinical Study Information Center 2020-09-17
MOM-COPE: Measuring Outcomes of Maternal COVID-19-related Prenatal Exposure Acute stress disorder, Coronavirus disease 19 infection Healthy volunteers accepted, Newborn Infants (up to 5 months), Infants (6-23 months) IRCCS C. Mondino National Institute of Neurology Foundation Italy 2020-05-06 2023-05-31 MOM-COPE, MOM-COPE, NCT04540029 Phase Not Applicable Recruiting 1 36 Months 600 Cinzia Fattore, Livio Provenzi, PhD, Serena Grumi, PhD 2020-09-11
COLCOVID19: Impact of Colchicine in Hospitalized Colombian Patients With COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome colchicine alone, standard therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundación Universitaria de Ciencias de la Salud Hospital de San Jose Colombia 2020-09-30 2020-12-31 5175, COLCOVID19, NCT04539873 Phase 3a Clinical Not yet recruiting 1 3 Months 128 ARLEY GOMEZ, MD, PhD, GIOVANNI MONTEALEGRE, MD. PS, HECTOR RESTREPO, JHON JAIME SPROCKEL, MD.IM, JHON JAIME SPROCKEL, MD, IM, WALTER CHAVES, MD. IM, WALTER CHAVES, MD, IM 2020-09-12
Estrogen Therapy in Non-severe COVID-19 Patients Coronavirus disease 19 infection norelgestromin + ethinylestradiol (contraceptive patch) Cygnus/RW Johnson alone Estradiol agonist, Progesterone receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) ISSSTE Centro Medico Nacional 20 de Noviembre Mexico 2020-10-01 2021-03-30 03, NCT04539626 Phase 2 Clinical Not yet recruiting 1 5 Months 60 Alberto H De la Vega Bravo, MD, Alfredo L Cortés Algara, MD, MSc, Cyndi Rodríguez Bandala, PhD, Daniel Santillán Cortés, MSc, Juan A Pineda Juárez, PhD, Maricela Escarela Serrano, MD, Mónica Escamilla Tilch, PhD, Paul Mondragón Terán, PhD, Rodrigo Ruz Barros, MD, Sandra Muñoz López, MD 2020-09-11
A clinical study of nitric oxide (inhaled), Ikaria in pregnant patients with severe and critical COVID-19 Coronavirus disease 19 infection nitric oxide (inhaled), Ikaria alone Hemoglobin modulator Massachusetts General Hospital Phase Not Applicable Planned 0 2020-09-10
Cyclosporine A Plus Low-steroid Treatment in COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia Variable regimens including ciclosporin, Novartis , clarithromycin , enoxaparin sodium , methylprednisolone Calcineurin inhibitor, Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto De Seguridad Y Servicios Sociales De Los Trabajadores Del Estado Mexico 2020-09-30 2020-09-30 135.2020, NCT04540926 Phase 1/Phase 2 Clinical Not yet recruiting 1 200 JOSE LUIS J GALVEZ-ROMERO, JOSE LUIS J GALVEZ-ROMERO, MD 2020-09-11
Electrolyte State in Patients With COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Zagazig University Egypt 2020-05-01 2020-10-01 (ZU-IRB#: 6328-23-8-2020), NCT04539834 Phase Not Applicable No longer recruiting 1 5 Months 52 Ahmed Abdulsaboor, MD, Essamedin Mamdouh Negm, lecturer, Hadeer El Shahaat, master degree, Tarek Hamdy, MD 2020-09-11
OPV-NA831: A Phase III, Randomized, Double-Blind, Efficacy and Safety Study of Oral Polio Vaccine and NA-831 for COVID-19 Coronavirus disease 19 infection bivalent oral polio vaccine (GSK) alone, traneurocin (Alzheimer's disease), NeuroActiva alone, bivalent oral polio vaccine (GSK) plus traneurocin (Alzheimer's disease), NeuroActiva AMPA receptor modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) NeuroActiva Inc Biomed Industries Inc US, New Zealand 2020-11-01 2022-12-31 NCT04540185, OPV-NA831, OPV-NA831 Phase 3 Clinical Recruiting 9 26 Months 3600 Lloyd Tran, PhD 2020-09-14
A phase I/II trial of EXG-5003 for the treatment of COVID-19 Coronavirus disease 19 infection EXG-5003 alone COVID19 Spike glycoprotein modulator Elixirgen Therapeutics Inc Japan 2021-03-31 Phase 1/Phase 2 Clinical Planned 1 2020-09-10
COVID-19 IgG Formation in Physicians at ALGH and Their Household Members Coronavirus disease 19 infection SARS-CoV-2 IgG testing alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Advocate HealthCare US 2020-08-26 2021-09-24 1606472-1, M5500436, NCT04540484 Phase Not Applicable Recruiting 1 12 Months 900 Katie Wozniak, Sigrun Hallmeyer, MD 2020-09-12
A phase I/II trial of AS-1411 for the treatment of COVID-19 Coronavirus disease 19 infection AS-1411 alone Qualigen Therapeutics Inc Phase 1/Phase 2 Clinical Planned 0 2020-09-10
Production of SARS-CoV-2 antigen specific immune cell therapy Coronavirus disease 19 infection, SARS coronavirus infection SARS-Coronavirus-2 (SARS-CoV-2) antigen specific T cells alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) The Catholic University of Korea Seoul St. Mary's Hospital South Korea 2020-07-21 KC20TSSI0274, KCT0005370 Phase 2 Clinical Recruiting 1 10 Jong Min Lee 2020-09-10
Study in Participants With Early Stage Coronavirus Disease 2019 (COVID-19) to Evaluate the Safety, Efficacy, and Pharmacokinetics of Remdesivir Administered by Inhalation Coronavirus disease 19 infection remdesivir (inhalant solution, COVID-19), Gilead alone COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gilead Sciences Inc US 2020-09-14 2020-12-31 GS-US-553-9020, NCT04539262 Phase 1/Phase 2 Clinical Recruiting 3 3 Months 282 Gilead Clinical Study Information Center, Gilead Study Director 2020-09-22
FamilyCoviDD19: Registry of SARS-CoV2-seroprevalence and transmission of Covid-19 infections in common households Coronavirus disease 19 infection SARS-CoV-2 antibody test alone University Hospital Carl Gustav Carus Germany 2020-09-01 BO-EK-342072020, DRKS00022564, FamilyCoviDD19 Phase Not Applicable Recruiting 1 250 Jakob Armann 2020-09-10
DIVI ECMO COVID Register: Investigation of clinical characteristics, management and outcome of ARDS patients: a Germany-wide register study Adult respiratory distress syndrome, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Wuerzburg University Hospital University of Wurzburg Germany 2020-07-16 131/20, DIVI ECMO COVID Register, DRKS00022964 Phase Not Applicable Recruiting 10 100 Patrick Meybohm, Peter Ulrich Heuschmann 2020-09-10
A phase II clinical study of CNM-ZnAg for the treatment of Coronavirus disease 19 infection in brazil Coronavirus disease 19 infection CNM-ZnAg alone Clene Nanomedicine Inc Brazil Phase 2 Clinical Planned 1 2020-09-14
A phase II clinical study of CNM-ZnAg for the treatment of Coronavirus disease 19 infection Coronavirus disease 19 infection CNM-ZnAg alone Clene Nanomedicine Inc Russian Federation Phase 2 Clinical Planned 1 2020-09-08
A survey of the impact of COVID-19 on the prescription and other conditions of patients with gastrointestinal diseases Coronavirus disease 19 infection, Gastrointestinal disease Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) EA Pharma Co Ltd Japan 2020-09-07 UMIN000041705 Phase Not Applicable Not yet recruiting 1 1000 Hisanori Masaki 2020-09-10
Pattern of acute MI admissions in India during COVID-19 era: a Cardiological Society of India study Coronavirus disease 19 infection, Myocardial infarction Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) India 2020-09-15 CTRI/2020/09/027613 Phase Not Applicable Not yet recruiting 11 30000 Dr Ajaykumar Pandey, Dr Anurag, Dr Chirag Patel, Dr Gurunath Parale, Dr Jay Shah, Dr Jayagopal, Dr Madhu, Dr Praveen Shukla, Dr Saket Joshi, Dr Sunil Thanvi, Dr Tarun, Geevar Zachariah 2020-09-14
Behavioral changes during COVID 19 among cricket players in India Coronavirus disease 19 infection, Psychiatric disorder Healthy volunteers accepted, Young Adults (18-44 yrs) India 2020-09-14 C3RF003, CTRI/2020/09/027596 Phase Not Applicable Not yet recruiting 1 50 Dr Harini Priyadharshini Muralidharan, Dr TR Muarlidharan 2020-09-11
A Study to create an artificial intelligence based risk assessment model to detect deterioration of patients clinical status Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Wipro Ltd India 2020-09-14 CTRI/2020/09/027595 Phase Not Applicable Not yet recruiting 1 500 Debendra Kumar Tripathy 2020-09-10
CVUM: To study the impact of corona virus pandemic on the cancer care of patients with urological cancers Bladder cancer, Coronavirus disease 19 infection, Prostate tumor, Renal tumor, Urinary tract tumor cancer care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tata Memorial Hospital India 2020-09-22 3489, CTRI/2020/09/027642, CVUM Phase Not Applicable Not yet recruiting 1 500 Dr Ganesh Bakshi 2020-09-10
Role of female sex hormone in COVID 19 patients Coronavirus disease 19 infection Estradiol Valerate alone, standard care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Government Institute of Medical Sciences, Greater Noida India 2020-09-08 CTRI/2020/09/027622 Phase 2 Clinical Not yet recruiting 1 64 Dr Shikha Seth 2020-09-10
Identification of SARS-CoV-2 in female genital tract and breast milk in confirmed cases of COVID-19 Coronavirus disease 19 infection Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute Of Medical Sciences, Rishikesh India 2020-09-14 CTRI/2020/09/027618 Phase Not Applicable Not yet recruiting 1 100 Dr Kavita Khoiwal 2020-09-10
A phase III clinical trial of bacteriophage-based COVID-19 vaccines for the potential prevention of COVID-19 Coronavirus disease 19 infection bacteriophage-based COVID-19 vaccines (oral lozenge, coronavirus disease 19 infection), Adaptive Phage Therapeutics alone Adaptive Phage Therapeutics Inc Phase 3 Clinical Planned 0 2020-09-10
Effect of COVID-19 positivity on pregnancy characteristics and pregnancy on infectivity potential of COVID-19 Coronavirus disease 19 infection, Pregnancy disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) All India Institute Of Medical Sciences, Rishikesh India 2020-09-14 CTRI/2020/09/027617 Phase Not Applicable Not yet recruiting 1 50 Dr Kavita Khoiwal 2020-09-09
Oral medicine trial for COVID 19 Coronavirus disease 19 infection Dashanga gulika & Haridra Khanda alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rajiv Gandhi University of Health Sciences India 2021-01-13 CTRI/2020/09/027616 Phase 1 Clinical Not yet recruiting 1 100 Dr Prashant A S 2020-09-14
Clinical trial of homeopathic medicine arsenic album as add on therapy in hospitalized patients admitted with Covid 19 disease Coronavirus disease 19 infection arsenic album alone, Variable regimens including favipiravir , hydrocortisone , meropenem , methylprednisone , monocef , piptaz , remdesivir , tocilizumab COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, Penicillin binding protein inhibitor, RNA polymerase inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) M.G.M. Medical College, Aurangabad 2020-09-11 CTRI/2020/09/027615 Phase Not Applicable Not yet recruiting 0 200 Dr Vishal Harilal Narwane 2020-09-09
Effectiveness of training programme on hand hygiene among laundry staff Coronavirus disease 19 infection training programme on hand hygiene alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Government Medical College Kannur India 2020-08-24 CTRI/2020/09/027614 Phase Not Applicable Not yet recruiting 1 14 Binoo Divakaran 2020-09-14
VA CURES-1: COVID-19 Coronavirus disease 19 infection convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) VA Office of Research and Development US 2020-09-21 2022-06-30 COVID19-8900-22, NCT04539275, VA CURES-1 Phase 3 Clinical Not yet recruiting 19 21 Months 702 Amit Gaggar, MD, Anthony Cannella, MD, Antonio Anzueto, MD, Edward N Janoff, MD, Edward N. Janoff, MD, Edwin Swiatlo, MD, Felipe Gutierrez, George Kurdgelashvili, MD, Jason Dazley, MD, Jeffrey Curtis, MD, Leroy Vaughan, MD, Maria Ribeiro, MD, Maria Rodriguez-Barradas, MD, Mitchell B Sally, MD, Norbert Brau, MD, Peruvemba Sriram, MD, Prakash Balasubramanian, MD, Roger Bedimo, MD, Sheldon T Brown, Suganthini Krishnan-Natesan, MD, Usha Stiefel, MD 2020-09-15
COVISTRESS Screening: Influence of the Covid-19 Pandemic on Stress, and Screening Procedures Acute stress disorder, Coronavirus disease 19 infection Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Clermont-Ferrand France 2020-05-01 2025-12-01 2020 COVISTRESS SCREENING, COVISTRESS Screening, NCT04538586 Phase Not Applicable Recruiting 1 67 Months 1000 Frederic DUTHEIL, Lise LACLAUTRE 2020-09-09
A pilot study to evaluate the accuracy and performance of the Shrelock CRISPR SARS-CoV-2 kit for the detection of nucleic acid from the novel coronavirus that causes COVID-19 Coronavirus disease 19 infection Shrelock CRISPR SARS-CoV-2 kit alone Sherlock Biosciences Inc US Phase Not Applicable Status not specified 1 20 Gregory J. Tsongalis 2020-09-07
The effect of mucodentol on COVID-19 symptoms Coronavirus disease 19 infection mucodentol (Khorraman co) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Shahid Beheshti University of Medical Sciences Iran 2020-05-21 IR.SBMU.RETECH.REC.1399.042, IRCT20200711048076N1 Phase 1 Clinical No longer recruiting 1 600 Behruz Farzan, Nina Farzan, Sahar Behzad 2020-09-10
VINCI: Absent Visitors: The Wider Implications of COVID-19 on Non-COVID Cardiothoracic ICU Patients, Relatives and Staff Cardiac arrest, Cardiac failure, Coronavirus disease 19 infection, Delirium, Lung disease advanced heart failure therapy alone, cardiac surgery alone, routine cardiac care alone, thoracic surgery alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Glasgow Golden Jubilee National Hospital UK 2020-09-30 2021-12-31 20/ANAES/02, NCT04538469, VINCI Phase Not Applicable Not yet recruiting 2 15 Months 1000 Ben Shelley, Dr Ben Shelley, Leah Hughes 2020-09-10
A case series of two COVID-19 patients with delirium Coronavirus disease 19 infection Levetiracetam alone, aciclovir alone, biomarker analysis alone, ceftriaxone alone, sodium valproate alone DNA polymerase inhibitor University of Nottingham Phase Not Applicable Status not specified 0 2 2020-09-07
Impact of COVID-19 on Lung Cancer Patients Coronavirus disease 19 infection, Non-small-cell lung cancer, Small-cell lung cancer Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The Christie NHS Foundation Trust 2020-09-30 2021-01-31 CFTSP189, NCT04538456 Phase Not Applicable Not yet recruiting 0 4 Months 800 2020-09-12
DAP-CORONA: A large phase III randomized clinical study of reformulated dapsone (COVID-19), McGill University Health Centre/Pulmonem to assess efficacy of a reformulated generic drug in COVID-19 positive outpatients to mitigate severe pulmonary inflammation caused by the SARS-CoV-2 virus Coronavirus disease 19 infection, Lung inflammation reformulated dapsone (iv,COVID-19), Pulmonem alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) Research Institute of the McGill University Health Centre Canada, US 2020-09-30 DAP-CORONA Phase 3 Clinical Planned 2 2000 Dr. Jean Bourbeau 2020-09-21
COVID-FIS: Pilot in COVID-19 (SARS-CoV-2) of Fisetin in Older Adults in Nursing Homes Coronavirus disease 19 infection, Inflammatory disease fisetin alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mayo Clinic, Minnesota National Institute on Aging US 2020-12-31 2023-12-31 1R01AG072301 - 01, 20-008867, COVID-FIS, NCT04537299 Phase 2 Clinical Not yet recruiting 1 36 Months 150 James L Kirkland, MD, PhD 2020-09-08
VIVID: Vitamin D and COVID-19 Trial Coronavirus disease 19 infection vitamin D3 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Brigham & Women's Hospital Fenway Community Health, Harvard Medical School, Harvard Pilgrim Health Care, Harvard TH Chan School of Public Health, Karolinska Institutet, Quest Diagnostics Inc, Takeda Pharmaceutical Co Ltd, Tishcon Corp US 2020-09-15 2021-01-15 2020J-009152, NCT04536298, VIVID Phase 3 Clinical Not yet recruiting 1 4 Months 2700 Davaasambuu Ganmaa, PhD, JoAnn E Manson, MD, DrPH, Rui Wang, PhD, Trisha Copeland, MS, RD 2020-09-09
A Study to Evaluate a Range of Dose Levels and Vaccination Intervals of Ad26.COV2-S in Healthy Adults Coronavirus disease 19 infection JNJ-78436735 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Janssen Vaccines & Prevention BV, Johnson & Johnson Netherlands, Germany, Spain 2020-08-28 2021-12-15 2020-002584-63, CR108854, NCT04535453, VAC31518COV2001 Phase 2a Clinical Recruiting 9 15 Months 550 Janssen Vaccines & Prevention B.V. Clinical Trial, Study Contact 2020-09-16
Study of Isoquercetin (IQC-950AN) Plus Standard of Care Versus Standard of Care Only for the Treatment of COVID-19 Coronavirus disease 19 infection IQC-950AN alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institut de Recherches Cliniques de Montreal Pharmascience Inc 2020-11-30 2021-05-31 IRCM-IQC-001, NCT04536090 Phase 2 Clinical Not yet recruiting 0 6 Months 150 Michel Chrétien, FRS MD FRCP© 2020-09-14
CCOVID-19: Efficacy and Safety of Direct Anti HCV Drugs in the Treatment of SARS-COV-2 (COVID-19) Coronavirus disease 19 infection, Viral pneumonia standard therapy alone, daclatasvir plus sofosbuvir Hepatitis C virus NS5B polymerase inhibitor, Hepatitis C virus protein NS5A inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mansoura University Egypt 2020-09-04 2021-09-03 CCOVID-19, MS.20.08.1214, NCT04535869 Phase 3 Clinical Not yet recruiting 1 12 Months 50 Hatem Elalfy, M.D, Mahmoud El-Bendary, M.D, Mahmoud Elbendary 2020-09-11
A Study of Brexanolone for Acute Respiratory Distress Syndrome Due to COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome brexanolone alone GABA A receptor modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) SAGE Therapeutics Inc 2020-11-30 2021-10-31 547-ARD-301, NCT04537806 Phase 3 Clinical Not yet recruiting 0 11 Months 100 Ariel Brown, PhD 2020-09-08
CINAMOPS: Critical Illness Polyneuropathy and Myopathy: Outcome, Predictors and Longitudinal Trajectories. A cohort study Coronavirus disease 19 infection, Myopathy, Polyneuropathy Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Schoen Clinic Bad Aibling Else Kröner-Fresenius Stiftung Germany 2020-09-15 20-166, CINAMOPS, DRKS00021753, U1111-1257-8461 Phase Not Applicable Not yet recruiting 1 250 Marion Egger 2020-09-10
Tomeka: COVID-19: Collecting Measurements of Renin-angiotensin-system Markers, Such as Angiotensin-2 and Angiotensin 1 to 7 Coronavirus disease 19 infection Tomeka alone, Vernonia amygdalina herbal therapy alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Kinshasa Congo, The Democratic Republic of the 2020-11-30 2022-12-31 NCT04537585, TOMEKA, Tomeka Phase Not Applicable Not yet recruiting 1 25 Months 2000 Guyguy K. Tshima, MD 2020-09-11
NoCOVImpact: Impact of COVID-19 Outbreak on Non-COVID-19 Patients Coronavirus disease 19 infection Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopitaux Universitaires De Geneve Switzerland 2020-03-01 2020-10-31 2020-01017, NCT04537559, NoCOVImpact Phase Not Applicable Recruiting 1 8 Months 40000 Aimad Ourahmoune, Christine Serratrice, Christophe Marti, Delphine Courvoisier, Dina Zekry, Eric Gerstel, Jacques Serratrice, Jean-Luc Reny, Jerome Stirnemann, MD, Mathieu Nendaz, Olivier Grosgurin, Omar Kherad, Pauline Darbellay, Sebastian Carballo, Thomas Agoritsas, Virginie Prendki 2020-09-09
A Comparison of Sample Collection Methods for SARS-COV-2 Antibody Testing Coronavirus disease 19 infection finger-stick method alone, saliva collection alone, traditional phlebotomy alone Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Salveo Diagnostics US 2020-09-30 2022-09-30 NCT04537572, R2020-1002 Phase Not Applicable Not yet recruiting 1 24 Months 300 Stephen A Varvel, PhD 2020-09-07
BCG-PRIME: Prevention Of Respiratory Tract Infection And Covid-19 Through BCG Vaccination In Vulnerable Older Adults Coronavirus disease 19 infection, Respiratory tract infection BCG-Vaccine-Danish strain 1331 alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitair Medisch Centrum Utrecht Netherlands 2020-08-25 2021-04-30 BCG-PRIME, BCG-PRIME, NCT04537663 Phase 4 Clinical Recruiting 19 8 Months 5200 Ad Dees Dees, MD, PhD, Annelies Verbon, MD, PhD, Barbara Munster Munster, MD, PhD, Coen Stehouwer, MD, PhD, Corine de Haas, Eefje Jong, MD, PhD, Frits Rosendaal, MD, PhD, Hazra Moeniralam, MD, PhD, Heidi Ammerlaan, MD, PhD, Henk Kramer, MD, PhD, Jacobien Hoogerwerf, MD, PhD, Jan Kluijtmans, MD, PhD, Jan-Jelrik Oosterheert, MD, PhD, Kees Brinkman, MD, PhD, Kees van Nieuwkoop, MD, PhD, Kitty Slieker, MD, Marc Bonten, MD, PhD., Martin Grobusch, MD, PhD, Mihai Netea, MD, PhD, Rob Slingerland, MD, PhD, Robert-Jan Hassing, MD, PhD, Ton Dofferhoff, MD, PhD, Walther Sipers, MD, PhD 2020-09-10
Study of Recombinant Protein Vaccine Formulations Against COVID-19 in Healthy Adults >/= 18 Years of Age Coronavirus disease 19 infection SARS-CoV-2 vaccine (COVID-19), Sanofi Pasteur/GlaxoSmithKline alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sanofi SA GlaxoSmithKline plc US 2020-09-03 2021-10-31 NCT04537208, U1111-1250-4757, VAT00001 Phase 1/Phase 2 Clinical Recruiting 3 13 Months 440 Clinical Sciences & Operations 2020-09-20
MEND: The Mesenchymal CoviD-19 Trial: a Pilot Study to Investigate Early Efficacy of MSCs in Adults With COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome mesenchymoangioblast-derived mesenchymal stem cell therapy (Cymerus, critical limb ischemia/graft versus host disease/asthma/diabetic foot ulcer), Cynata/FUJIFILM alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cynata Therapeutics Ltd Cerebral Palsy Alliance Research Foundation Australia 2020-08-24 2021-03-31 ACTRN12620000612910, ANZCTR379838, CYP-COVID-19-01, MEND, NCT04537351 Phase 1/Phase 2 Clinical Recruiting 2 7 Months 24 A/Prof Vineet Nayyar, Cynata Project Manager, Dr Madison Paton, Kilian Kelly, PhD 2020-09-15
Virtual Reality Therapy Influence on Heart Rate Variability of Inpatients With COVID-19 Coronavirus disease 19 infection MoveHero (University of Sao Paulo) alone, conventional exercise alone, virtual reality therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Sao Paulo Federal University of Sao Paulo Brazil 2020-06-18 2020-12-01 33244620.5.0000.5505, NCT04537858 Phase Not Applicable No longer recruiting 1 5 Months 50 Talita D da Silva, Ph.D., Talita Dias da Silva 2020-09-08
RESPIRA: Evaluation of the Immune Response to SARS-CoV-2 Among Patients With Covid-19 in Costa Rica Coronavirus disease 19 infection Healthy volunteers accepted, Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Deutsches Krebsforschungszentrum, Fundación Inciensa, Ministry of Health of Costa Rica, National Institutes of Health Costa Rica 2020-09-14 2022-09-14 NCT04537338, R020-SABI-00261, RESPIRA Phase Not Applicable Not yet recruiting 1 24 Months 2000 Rebeca Ocampo, Médica, Rolando Herrerro, Médico, Viviana Loría, Médica 2020-09-07
COVINVAC: Vaccination of Ex-acute COVID-19 Patients With Fibrosing Lung Syndrome at Discharge Coronavirus disease 19 infection, Interstitial lung disease, Pulmonary fibrosis, Respiratory disease, Viral pneumonia IN-01 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto Oncologico Rosell, Barcelona, Spain In3bio Ltd Spain 2020-12-01 2022-06-30 2020-002874-28, COVINVAC, NCT04537130, PANIN3BIO/IN01_COVID19_01 Phase 1b Clinical Not yet recruiting 1 19 Months 40 Federico Nepote, Investigator Selected by Sponsor, Pablo Rubinstein, MD, MSc, PhD, Verónica Roca 2020-09-10
The Co-CLARITY Trial: A Randomized, Non-Placebo Controlled, Open-Label, Single-Center Clinical Trial to Assess the Efficacy and Safety of Convalescent Plasma Given in Two Consecutive Aliquots to Hospitalized Adult COVID-19 Patients as Adjunctive Therapy to Reduce the Need for ICU Admission Coronavirus disease 19 infection convalescent plasma therapy alone University of the Philippines Manila Philippine Council for Health Research and Development Philippines 2020-07-01 2021-07-01 2020-CT0554, PHRR200824-002868, The Co-CLARITY Trial, UPMREB 2020-300-01 Phase 3 Clinical Not yet recruiting 1 12 Months 136 Deonne Thaddeus Gauiran 2020-09-09
Compare marker abnormalities in COVID positive and negative cancer patients Coronavirus disease 19 infection general anesthesia alone, surgery alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute Of Medical Sciences, Rishikesh India 2020-09-13 CTRI/2020/09/027518 Phase Not Applicable Not yet recruiting 1 40 Bhavna Gupta 2020-09-07
Knowledge, Attitudes and Clinical Practices of Pediatric Dentists Regarding Covid-19 Coronavirus disease 19 infection Fayoum University, EG Egypt 2020-04-20 2020-05-05 NCT04537117, PEDODONTISTS DURING COVID-19 Phase Not Applicable Completed 1 202 Maha M Azab, PhD 2020-09-07
Swallowing Impairment After COVID-19 Infection Coronavirus disease 19 infection, Dysphagia Oropharyngeal swallowing examination alone, Videofluoroscopy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The University Health Network McMaster University, National Institute on Deafness and Other Communication Disorders, University of Florida US, Canada 2020-09-01 2021-12-31 3R01DC011020-08S1, CAPCR 20-5477, NCT04537650 Phase Not Applicable Not yet recruiting 2 16 Months 75 Ashwini M Namasivayam-MacDonald, PhD, Catriona M Steele, PhD, Emily K Plowman, PhD, Renata Mancopes, PhD 2020-09-09
A Trial Investigating the Safety and Effects of One BNT-162 Vaccine Against COVID-19 in Healthy Adults Coronavirus disease 19 infection BNT-162b3 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) BioNTech RNA Pharmaceuticals GmbH BioNTech SE Germany 2020-09-09 2021-12-31 2020-003267-26, BNT162-04, NCT04537949, U1111-1254-4840 Phase 1/Phase 2 Clinical Recruiting 2 15 Months 120 BioNTech Responsible Person, BioNTech clinical trial information desk, BioNTech clinical trials patient information 2020-09-16
C2Rx Hemofiltration Treatment in Severe or Critically Ill Adults With COVID-19 Coronavirus disease 19 infection, Respiratory failure CLR2.0 device alone, hemofiltration alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Seastar Medical Inc 2020-09-15 2021-01-15 CP-01-004, NCT04537975 Phase Not Applicable Not yet recruiting 0 4 Months 30 Eric Schlorff 2020-09-07
Covid 19 and Professional course students quality of life Coronavirus disease 19 infection web based survey alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Haldia Institute of Dental Sciences & Research India 2020-09-10 CTRI/2020/09/027544 Phase Not Applicable Not yet recruiting 1 636 Arnab Ganguly, Swet Nisha 2020-09-04
Management of cardiac disease during COVID-19 pandemic and impact among cardiologist in Tamil Nadu Acute coronary syndrome, Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) India 2020-09-07 C3RF002, CTRI/2020/09/027517 Phase Not Applicable Not yet recruiting 1 100 Dr B Vinod Kumar, Dr S Nagendra Boopathy, Dr T R Muralidharan 2020-09-09
Coronavirus infection among healthcare workers Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) B.Y.L Nair Charitable Hospital India 2020-09-07 CTRI/2020/09/027516 Phase Not Applicable Not yet recruiting 1 500 Dr Niraj Mahajan 2020-09-07
Effects of health drink additional to standard of care treatment in COVID 19 patients Coronavirus disease 19 infection Mulmina Mango alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Jagdale industries pvt Ltd India 2020-09-12 CTRI/2020/09/027548 Phase Not Applicable Not yet recruiting 1 50 Dr MS Madhu, Raghavendra KV, Subham Dutta 2020-09-08
Efficacy and safety study of antiviral Umifenovir therapy in non-severe COVID- 19 patients Coronavirus disease 19 infection Umifenovir alone, standard care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Central Drug Research Institute India 2020-09-08 CDRI-CLINICAL2/2020, CTRI/2020/09/027535, U1111-1251-8421 Phase 3 Clinical Not yet recruiting 3 132 Dr M MA Faridi, Dr Virendra Atam, Dr Vivek Bhosale MD, v 2020-09-08
A phase II trial to evaluate galidesivir in non-hospitalized COVID-19 patients at high risk for developing severe disease and complications of COVID-19 Coronavirus disease 19 infection galidesivir alone RNA polymerase inhibitor BioCryst Pharmaceuticals Inc Phase 2 Clinical Planned 0 2020-09-04
Effects of Early Use of Nitazoxanide in Patients With COVID-19 Coronavirus disease 19 infection nitazoxanide alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Associacao Paulista para o Desenvolvimento da Medicina, Hospital e Maternidade Therezinha de Jesus, Universidade Federal do Rio de Janeiro Conselho Nacional de Desenvolvimento Cientifico e Tecnologico - CNPq, Ministry of Science and Technology, Brazil, Ministério da ciência, tecnologia e inovação fundação de amparo a pesquisa do estado de São Paulo, National Research Council, Brazil, Secretaria de Estado da Saude, Secretaria de Saúde do Distrito Federal Brazil 2020-06-08 2020-09-05 32258920.0.1001.5257, 4.043.191, NCT04552483, RBR-4nr86m Phase 3 Clinical Completed 2 2 Months 392 Patricia RM Rocco, MD, PhD 2020-09-18
PGE1-COVID19: Cri Analog PG1 Effectiveness and Safety in Covid-19 Coronavirus disease 19 infection, Hypoxia, Respiratory disease, Viral pneumonia empirical antibiotic therapy alone, Variable regimens including alprostadil , dexamethasone , enoxaparin sodium , low molecular weight heparin , tocilizumab Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundacion Santa Fe De Bogota Colombia 2020-10-01 2021-03-01 CEIS-2020-089, NCT04536363, PGE1-COVID19 Phase 2 Clinical Not yet recruiting 1 5 Months 284 Alonso Vera Torres, Alonso Vera Torres, MD, Jose De la Hoz, MD 2020-09-08
LIVE: Live@Home.Path: Innovating the Clinical Pathway for Home Dwelling Persons With Dementia and Their Families Coronavirus disease 19 infection, Dementia LIVE alone, multicomponent intervention alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Bergen Haraldsplass Deaconess Hospital, King's College London, McLean Hospital Corp, National Association for Public Health, Norwegian National Advisory Unit on Rare Disorders, Norwegian Research Centre, The University of Hong Kong, Tohoku University, Universiteit Leiden, University College London, Western Norway University of Applied Sciences, Yale School of Medicine Norway 2019-08-01 2021-06-30 LIVE, NCT04043364, NFR 273581 Phase Not Applicable Recruiting 1 23 Months 312 Bettina Husebø, MD, PhD, Bettina Husebø, MD,PhD, Line I Berge, MD,PhD 2020-09-08
COVID-19 Related Public Health Literacy Coronavirus disease 19 infection Health infographics through facebook application alone Malaysia 2020-11-02 2021-05-17 56068, NMRR-20-1867-56068 Phase Not Applicable Status not specified 1 6 Months PUAN NOR AYUNI BINTI AB RAHMAN 2020-09-08
Effect of prone positioning with HFNC on oxygenation and overall outcomes in severe COVID-19 patients Coronavirus disease 19 infection, Respiratory failure High Flow Nasal Cannula alone, Prone Positioning alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Maulana Azad Medical College India 2020-10-01 CTRI/2020/09/027562, F.1/IEC/MAMC/79/07/2020/200 Phase Not Applicable Not yet recruiting 1 92 Dr Amit Kohli, Dr Deepak Kumar 2020-09-09
Detection of specific antibodies (IgM and IgG) in sera from patients with COVID-19 and patients under investigation for COVID-19 in Malaysia Coronavirus disease 19 infection National Institutes of Health Malaysia Malaysia 2020-09-07 2021-05-31 55677, NMRR-20-1866-55677 Phase Not Applicable Status not specified 1 8 Months Dr ROZAINANEE MOHD ZAIN 2020-09-08
Identifying homeopathy medicines in use for protection against COVID-19, calculating the number of COVID-19 cases or cases with COVID-19 like symptoms in these homeopathy users and identifying some general features like age, gender and location in them Coronavirus disease 19 infection homeopathy medicines alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Australia, US, Thailand, Singapore, Belgium, Sweden, Hong Kong, Canada, China, Switzerland, United Arab Emirates, Norway, Germany, India, UK, Italy 2020-09-15 CTRI/2020/09/027560, U1111-1255-9014 Phase Not Applicable Not yet recruiting 17 6500 Kushal Banerjee 2020-09-08
CPCP: Clinical Pharmacist in a COVID Hospital - A Malaysian Experience Coronavirus disease 19 infection Hospital Sungai Buloh Malaysia 2020-08-29 2020-12-31 55720, CPCP, NMRR-20-1854-55720 Phase Not Applicable Status not specified 1 4 Months Miss PEE LAY TING 2020-09-07
First Responder Resiliency Program During COVID-19 Coronavirus disease 19 infection Resilience Program alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mayo Clinic Foundation US 2020-09-15 2021-12-31 20-005017, NCT04536376 Phase Not Applicable Not yet recruiting 1 15 Months 10 Brent Bauer, MD, Ivana T Croghan, PhD, Shawn C Fokken, BS, Stephanie A Lindeen, RN 2020-09-07
Assessing People's Hospital Outpatient Appointment Preferences in the United Kingdom Coronavirus disease 19 infection, Diabetes mellitus, Heart disease, Stroke Active Choice alone, In-Person Default alone, Video Default alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Warwick University UK 2020-09-01 2020-09-30 BSREC 110/19-20, NCT04536259 Phase Not Applicable Not yet recruiting 1 1 Month 1000 Kelly A Schmidtke, PhD 2020-09-08
Hospitalized Children and Adolescent Patients With Type 1 Diabetes During the COVID-19 Pandemic in Egypt Coronavirus disease 19 infection, Insulin dependent diabetes Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Ain Shams University Egypt 2020-05-01 2020-08-31 FMASU P59/2020, NCT04536285 Phase Not Applicable Completed 1 4 Months 36 Eman Monir Sherif, Yasmine Elhenawy 2020-09-09
Biosurveillance and KAP COVID-19 cats Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Malaysia 2020-10-01 2021-01-31 55758, NMRR-20-1834-55758 Phase Not Applicable Not yet recruiting 3 4 Months Dr Farina Binti Mustaffa Kamal, Dr Nur Indah Binti Ahmad 2020-09-08
COMPASS: An Online Cognitive-behavioural Therapy (CBT) Program Treating Anxiety and Low Mood in Long-term Conditions During the COVID-19 Pandemic Anxiety disorder, Coronavirus disease 19 infection COMPASS alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) King's College London Diabetes UK, Multiple Sclerosis (MS) Society, UK UK 2020-09-28 2021-06-01 20347, COMPASS, NCT04535778 Phase Not Applicable Not yet recruiting 1 8 Months 200 Katrin Hulme, Natasha Seaton, Natasha Seaton, Msc, Rona Moss-Morris 2020-09-08
Evaluation of the Load of SARS-CoV-2 Virus in Oral Cavity, Oropharinge and Saliva of Patients With Covid-19 After Disinfection With Oral Antimicrobial Solutions: a Pilot Study Coronavirus disease 19 infection Colgate Peroxyl mouthwash alone, Colgate Total mouthwash alone, Colgate periogard mouthwash alone, Colgate Peroxyl mouthwash plus Colgate periogard mouthwash Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sociedade Beneficente Israelita Brasileira Hospital Albert Einsten Brazil 2020-06-11 2021-08-30 4172-20, NCT04537962 Phase Not Applicable Recruiting 1 14 Months 70 Debora H Douek, PhD, Luciana Correa, PhD 2020-09-14
Mobile Mental Health Apps for Suicide Prevention Anxiety disorder, Coronavirus disease 19 infection, Depression Mobile Mental Health App - 1 alone, Mobile Mental Health App - 10 alone, Mobile Mental Health App - 2 alone, Mobile Mental Health App - 3 alone, Mobile Mental Health App - 4 alone, Mobile Mental Health App - 5 alone, Mobile Mental Health App - 6 alone, Mobile Mental Health App - 7 alone, Mobile Mental Health App - 8 alone, Mobile Mental Health App - 9 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Washington 2020-09-30 2020-12-31 NCT04536935, STUDY00010842 Phase Not Applicable Not yet recruiting 0 3 Months 2000 Brittany Mosser, MSW, Kate Comtois, PhD 2020-09-08
Ultra-brief Online Mindfulness-based Intervention During COVID-19 Movement Control Order Coronavirus disease 19 infection Ultra Brief Online Mindfulness-based Intervention alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universiti Tunku Abdul Rahman Sunway University Malaysia 2020-04-01 2020-06-30 NCT04536441, U/SERC/62/2020 Phase Not Applicable Completed 1 3 Months 161 Kai-Shuen Pheh, MClinPsych 2020-09-08
Dental Students Health and Well being During Covid-19 Pandemic Coronavirus disease 19 infection Healthy volunteers accepted, Female, Young Adults (18-44 yrs) Haldia Institute of Dental Sciences & Research India 2020-09-10 CTRI/2020/09/027558 Phase Not Applicable Not yet recruiting 1 480 Arnab Ganguly, Swet Nisha 2020-09-04
Efficacy of Vitamin D Supplementation to Prevent the Risk of Acquiring COVID-19 in Healthcare Workers (COVID-19) Coronavirus disease 19 infection vitamin D alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Coordinacion de Investigacion en Salud Hospital Infantil de Mexico Federico Gomez Mexico 2020-07-15 2021-07-31 NCT04535791, R-2020-785-090 Phase 3 Clinical Recruiting 1 12 Months 400 Carla Castuera Martinez, Clara Santacruz-Tinoco, PhD, Concepcion Grajales-Muñiz, PhD, Guadalupe Miranda-Novales, PhD, Jessie Zurita-Cruz, MD, Jessie Zurita-Cruz, PhD, Mardia Lopez-Alarcon, PhD, Miguel Angel Villasis-Keever, Miguel Angel Villasis-Keever, MD, Miguel Angel Villasis-Keever, PhD 2020-09-08
Effect of comorbidities in the outcome of COVID-19 patients, a study in tertiary care centre ICU in India Coronavirus disease 19 infection, Respiratory tract infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Vardhman Mahavir Medical College & Safdarjung Hospital India 2020-09-14 CTRI/2020/09/027572 Phase Not Applicable Not yet recruiting 1 350 Deepa Kerketta Khurana 2020-09-04
Inhaled Aviptadil for the Prevention of COVID-19 Related ARDS Coronavirus disease 19 infection, Respiratory distress syndrome aviptadil alone, standard care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kantonsspital Baselland Switzerland 2020-09-30 2022-03-31 AVIPTADIL TRIAL, NCT04536350 Phase 1 Clinical Not yet recruiting 2 18 Months 80 Jörg D Leuppi, Professor, Kristin Abig, Michael Brändle, Professor, Prof. Dr. Jorg Leuppi 2020-09-09
A case-study of critically ill COVID-19 patient who showed successful response to plasma exchange followed by intravenous immunoglobulin Coronavirus disease 19 infection, Respiratory failure intravenous immunoglobulin alone, plasma exchange alone Female People's Hospital of Guizhou Province Phase Not Applicable Status not specified 0 1 2020-09-04
An observational, case report to determine the safety and efficacy of triple combination therapy with lopinavir/ritonavir, hydroxychloroquine, and interferon beta-1b in COVID-19 pneumonia patients Coronavirus disease 19 infection, Pneumonia Variable regimens including hydroxychloroquine , interferon beta-1b , lopinavir + ritonavir , methylprednisolone HIV protease inhibitor National Research Foundation of Korea Phase Not Applicable Status not specified 0 5 2020-09-04
ADAPT-C: Community-based cohort of people tested for COVID-19 Coronavirus disease 19 infection serological assay alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) St Vincents Hospital Sydney Ltd St Vincent's Clinic Australia 2020-08-18 2023-04-01 ACTRN12620000854932, ADAPT-C, ANZCTR380379 Phase Not Applicable Recruiting 1 31 Months 150 Fiona Jane Kilkenny, Gail Matthews 2020-09-11
An observational, cohort study to evaluate the impact of addition of corticosteroids to the hospital protocol in treatment of patients with suspected or confirmed COVID-19 pneumonia Coronavirus disease 19 infection, Pneumonia corticosteroids alone Centre Hospitalier Universitaire de Reims Phase Not Applicable Status not specified 0 257 2020-09-04
C-SMART (Arm 1): C-SMART. COVID-19 Prevention and Treatment in Cancer. Arm 1 : Prevention in Patients Not Infected with COVID-19 Coronavirus disease 19 infection Variable regimens including interferon-alpha , lenzilumab , selinexor Exportin 1 inhibitor, GM-CSF ligand inhibitor, Immunoglobulin G1 modulator, Immunoglobulin kappa modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Peter MacCallum Cancer Centre Australian Government Australia 2020-09-01 2021-12-01 ACTRN12620000843954, ANZCTR380380, C-SMART (Arm 1), HREC/65954/PMCC, U1111-1256-8488 Phase 3 Clinical Not yet recruiting 5 15 Months 1914 Michelle Yong, Monica Slavin, Ronan Burder 2020-09-09
Increasing immunization in general practice against invasive pneumococcal disease and influenza in people < 65 years old whose chronic conditions put them at higher risk of and from these infections Coronavirus disease 19 infection, Influenza virus infection, Streptococcus pneumoniae infection Doctor's control panel software (DCP) alone, SMS immunization reminder alone, reminder letter alone, telehealth consultation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) University of Adelaide Australia 2020-06-08 ACTRN12620000614998, ANZCTR379321, H-2020-044 Phase Not Applicable Not yet recruiting 1 6000 Oliver Frank 2020-09-04
A research study to determine the effect of a smartphone application (app) on management of patients with heart failure in isolation due to COVID-19 Cardiac failure, Coronavirus disease 19 infection smartphone application (app) alone, standard care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Wesley Research Institute Australia 2020-09-01 ACTRN12620000860965, ANZCTR380420 Phase Not Applicable Not yet recruiting 1 400 John Rivers 2020-09-12
C-SMART (Arm 2): COVID-19 prevention and treatment in cancer. Arm 2: post-exposure prevention in patients recently exposed to COVID-19 Coronavirus disease 19 infection, Respiratory tract infection interferon-alpha alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Australian Government, Peter MacCallum Cancer Centre Australia 2020-09-01 2021-12-01 ACTRN12620000842965, ANZCTR380422, C-SMART (Arm 2), HREC/65954/PMCC, U1111-1256-8488 Phase 3 Clinical Not yet recruiting 5 15 Months 170 Michelle Yong, Monica Slavin, Ronan Burder 2020-09-05
A trial to evaluate VIR-7831 for the prophylaxis of symptomatic COVID-19 infection Coronavirus disease 19 infection VIR-7831 alone COVID19 Spike glycoprotein modulator Vir Biotechnology Inc Phase Not Applicable Planned 0 2020-09-03
A trial to evaluate VIR-7831 for the treatment of severely ill hospitalized COVID-19 patients Coronavirus disease 19 infection VIR-7831 alone COVID19 Spike glycoprotein modulator Vir Biotechnology Inc Phase Not Applicable Planned 0 2020-09-03
Therapeutic Study to Evaluate the Safety and Efficacy of DW-MSC in COVID-19 Patients Coronavirus disease 19 infection DWP-710 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) INA-RESPOND Secretariat Daewoong Pharmaceutical Co Ltd, National Institute Of Health Research & Development (Nihrd)- Ministry Of Health Of The Republic Of Indonesia Indonesia 2020-09-11 2020-12-31 DW_DWP710101, NCT04535856 Phase 1 Clinical Not yet recruiting 1 3 Months 9 Dr. Muhammad Karyana, MPH, dr. Dona Arlinda, M.Sc. 2020-09-14
Treatment for Severe Pneumonia in Patients with Coronavirus Coronavirus disease 19 infection, Viral pneumonia EF-168 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ministério da ciência, tecnologia e inovação fundação de amparo a pesquisa do estado de São Paulo Financiadora de Estudos e Projetos Brazil 2020-04-30 3.979.532, 30662420.0.1001.0008, B878.596.297-04, RBR-88bs9x Phase 3 Clinical Recruiting 1 500 Fernanda Ferreira Cruz, Patricia Rieken Macedo Rocco, Pedro Leme Silva 2020-09-09
Umbilical cord-derived mesenchymal stromal cells therapy for SARS-CoV-2 infection (COVID-19) related Acute Respiratory Distress Syndrome Coronavirus disease 19 infection, Respiratory distress syndrome HLC-001 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Human Life CORD Japan Inc Japan 2020-10-01 2021-09-30 JapicCTI-205465 Phase 1 Clinical Not yet recruiting 1 12 Months 12 2020-09-05
To study ease of using intubation(aerosol) box in patients undergoing general anesthesia for elective surgeries during the coronavirus disease pandemic Coronavirus disease 19 infection, General anesthesia Endotracheal intubation alone, modified aerosol box alone, Variable regimens including fentanyl , glycopyrrolate , midazolam hydrochloride , oxygen , propofol, AstraZeneca/Fresenius , succinyl-choline Benzodiazepine receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Jawaharlal Nehru Medical College KLES Prabhakar Kore Hospital and Medical Research Center India 2020-09-01 CTRI/2020/08/027489, U1111-1256-5515 Phase 2 Clinical Not yet recruiting 1 110 DrNeha Sanjeev Adhyapak, DrRajesh S Mane 2020-09-03
The Incidence of Critical Illness Related Corticosteroid Insufficiency and Clinical Outcomes of Critically Ill Patients with COVID-19 at the Philippine General Hospital Coronavirus disease 19 infection Philippine General Hospital Philippines 2020-06-01 PHRR200827-002884 Phase Not Applicable Not yet recruiting 1 Anna Elvira Arcellana 2020-09-03
The impact of work loss during the COVID-19 pandemic on health and employment Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Monash University iCare Foundation Australia 2020-03-27 2020-12-31 #24003, ACTRN12620000857909, ANZCTR380413 Phase Not Applicable No longer recruiting 1 9 Months 1829 Alex Collie 2020-09-12
Selfhelp in Covid -19 Pandemic: Health-related self-help strategies during the COVID-19 pandemic - an online-based cross-sectional study Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Charite Universitaetsmedizin Berlin Germany 2020-09-15 DRKS00022909, EA2/127/20, Selfhelp in Covid -19 Pandemic Phase Not Applicable Not yet recruiting 1 2000 Margit Cree, Miriam Ortiz 2020-09-07
Seroprevalence of COVID-19 in Thailand Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) King Chulalongkorn Memorial Hospital Thailand 2020-09-15 TCTR20200828001 Phase Not Applicable Not yet recruiting 1 400 Nattachai Srisawat 2020-09-07
Seroprevalence of SARS-CoV-2 in communities in the Philippines Coronavirus disease 19 infection Research Institute for Tropical Medicine Philippine Council for Health Research and Development, Research Institute for Tropical Medicine Philippines 2020-07-27 PHRR200825-002878 Phase Not Applicable Not yet recruiting 2 4000 Catalino S. Demetria, DVM, Criselda T. Bautista, DVM, MVetEpi, Johanna Beulah T. Sornillo, Kristine Alvarado-Dela Cruz, MD, FPPS, DPIDSP, Marianette T. Inobaya, MSPH,PhD, Mayan U. Lumandas, MD, FPPS, DPIDSP, MSc, Timothy John R. Dizon, MD, MBA 2020-09-07
CORONA-VTE NET: COVID-19 Registry to Assess Frequency, Risk Factors, Management, and Outcomes of Arterial and Venous Thromboembolic Complications Bleeding, Coronavirus disease 19 infection, Deep vein thrombosis, Ischemia, Lung embolism, Myocardial infarction, Stroke, Thromboembolism Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Brigham & Women's Hospital Anne Arundel Medical Center, Beth Israel Deaconess Medical Center, Bristol-Myers Squibb Co, Jefferson Medical College, University of Colorado US 2020-03-24 2021-03-30 2020P000848, CORONA-VTE NET, NCT04535128 Phase Not Applicable Recruiting 1 12 Months 10000 Gregory Piazza, MD, MS 2020-09-07
How Brazilian Chiropractors Are Facing the COVID-19 Pandemic Coronavirus disease 19 infection Healthy volunteers accepted Brazil 2020-08-26 2020-09-18 NCT04534621, Treat Phase Not Applicable Not yet recruiting 1 948 MARCELO B BOTELHO, DC, MD, MSc 2020-09-04
Efficacy of Family Programs for Improving Child and Family Health and Development Coronavirus disease 19 infection Couples intervention alone, Home visits alone, Sensitivity intervention alone, Zoom app alone Healthy volunteers accepted, Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The University of Notre Dame du Lac Eunice Kennedy Shriver National Institute of Child Health & Human Development US 2017-01-11 2023-12-31 NCT03367845, NotreDame, R01HD087319 Phase Not Applicable Recruiting 2 83 Months 1200 Cheryl Lee, MA, E M Cummings, Ph.D., Julia Braungart-Rieker, Ph.D, Kathleen Bergman, PhD, Terri Sweeney, BA 2020-09-07
Consequences of the COVID-19 Lockdown on Health and Well-being of Patients With Parkinson Disease and Post-stroke Coronavirus disease 19 infection, Parkinsons disease, Stroke Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Haifa Israel 2020-05-10 2020-06-30 203/20, NCT04535297 Phase Not Applicable Completed 1 1 Month 198 Galit Yogev-Seligmann 2020-09-04
Mother-infant Bonding During COVID-19 Coronavirus disease 19 infection Family Nurture Intervention (FNI) alone Healthy volunteers accepted, Newborn Infants (up to 5 months) Columbia University US 2020-08-13 2021-12-31 AAAT0140, NCT04531618 Phase Not Applicable Recruiting 1 16 Months 280 Dani Dumitriu, Dani Dumitriu, MD, PhD, Martha Welch, MD 2020-09-04
Convalescent Plasma as Potential Therapy for Severe COVID-19 Pneumonia Coronavirus disease 19 infection, Multiple organ failure, Respiratory failure, Septic shock, Viral pneumonia Architect Plus, Abbott alone, COVID19 convalescent plasma alone, Chemiluminescent microparticle immunoassay alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centro de Educación Medica e Investigaciones Clínicas Norberto Quirno Argentina 2020-04-18 2021-02-25 NCT04535063, RValentini Phase 3 Clinical Recruiting 1 10 Months 200 Jorge Solimano, MD, José Fernández Grande, MD, Juan Dupont, MD, Ricardo Valentini, MD 2020-09-04
PROLUN: Patient-reported Outcomes and Lung Function After Hospitalization for COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Akershus Haukeland University Hospital, Oslo University Hospital, Ostfold Hospital Trust, St Olavs Hospital Norway 2020-03-31 2022-06-01 NCT04535154, PROLUN, PROLUN Phase Not Applicable No longer recruiting 1 26 Months 264 Gunnar Einvik, PhD 2020-09-06
Pegylated Interferon Lambda for Treatment of COVID-19 Infection Coronavirus disease 19 infection, Respiratory tract infection Standard of care alone, pegylated interferon lambda alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Soroka University Medical Center Israel 2020-08-05 2021-12-31 0129-20-SOR, NCT04534673, SCRC200006 Phase 2 Clinical Recruiting 1 16 Months 40 Ohad Etzion, MD, Ruthie Bekore 2020-09-07
QUANTICO-RETRO: Automated Quantification of Radiological Pulmonary Alteration During Acute Respiratory Failure Coronavirus disease 19 infection, Hypoxia, Respiratory failure thoracic CT-scan alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopitaux Universitaires de Strasbourg Visible Patient France 2020-09-01 2021-01-15 7888, NCT04534400, QUANTICO-RETRO Phase Not Applicable Recruiting 2 4 Months 1000 Bernard GOICHOIT, MD, Eric NOLL, MD, Francis SCHNEIDER, MD, Francis VEILLON, MD, Julien POTTECHER, MD, Mickaël OHANA, MD, Philippe FEUERSTEIN, MD, Pierre DIEMUNSCH, MD 2020-09-05
C-SMART: COVID-19 Prevention and Treatment in Cancer: a Sequential-Multiple-Assignment, Randomized Trial Coronavirus disease 19 infection, Respiratory tract infection, Viral pneumonia interferon-alpha alone, lenzilumab alone, selinexor alone Exportin 1 inhibitor, GM-CSF ligand inhibitor, Immunoglobulin G1 modulator, Immunoglobulin kappa modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Peter MacCallum Cancer Centre Australia 2020-09-30 2021-12-31 C-SMART, NCT04534725, Peter Mac ID 20/135 Phase 3 Clinical Not yet recruiting 1 15 Months 2282 Megan Crane, Ronan Burder 2020-09-10
Lymphocyte - Monocyte Ratio As An Independent Predictor For Progression Of Illness In Patients With Covid-19 Coronavirus disease 19 infection, Viral pneumonia lymphocyte monocyte ratio prediction test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Postgraduate Institute of Medical Education and Research Sir Ganga Ram Hospital India 2020-09-01 2021-02-01 NCT04534712 Phase Not Applicable Not yet recruiting 1 5 Months 100 vamsidhar amburu, MD 2020-09-04
C19CHILD: COVID-19 Child Health Investigation of Latent Disease in Hamburg Coronavirus disease 19 infection Immunological analysis alone, Obligatory polymerase chain reaction alone, Serum antibody testing alone Healthy volunteers accepted, Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Universitätsklinikum Hamburg-Eppendorf Altona children's hospital, Asklepios Kliniken Hamburg GmbH, Helios Mariahilf Klinik Hamburg, Wilhelmstift Childrens Hospital Germany 2020-05-11 2021-03-31 C19CHILD, NCT04534608, PV7336 Phase Not Applicable No longer recruiting 1 10 Months 6000 Ania C Muntau, Professor, Soeren W Gersting, Professor, Thomas Mir, Professor 2020-09-20
Effect of curcumin in treatment of respiratory syndrome of corona Coronavirus disease 19 infection curcumin (Dineh Company) alone, usual medications alone Kermanshah University of Medical Sciences Iran 2020-08-31 IR.KUMS.REC.1398.1223, IRCT20200418047119N1 Phase 2/Phase 3 Clinical Recruiting 1 42 Mohammad Hossein Zamanian, Sajad Moradi 2020-09-04
First-In-Human Study To Evaluate Safety, Tolerability And Pharmacokinetics Following Single Ascending Dose And Extended Infusion of PF-07304814 In Hospitalized Participants With COVID-19 Coronavirus disease 19 infection PF-07304814 alone COVID19 replicase polyprotein 1a inhibitor, COVID19 replicase polyprotein 1ab inhibitor, Viral protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Pfizer Inc 2020-08-30 2021-02-27 2020-003905-73, C4611001, NCT04535167 Phase 1b Clinical Not yet recruiting 0 5 Months 56 Pfizer CT.gov Call Center 2020-09-09
RECHARGE: A Brief Psychological Intervention to Build Resilience in Healthcare Workers During COVID-19 Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder RECHARGE alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Zurich University of New South Wales Switzerland 2020-08-28 2021-06-01 BASEC-Nr.2020-00796, NCT04531774, RECHARGE Phase Not Applicable Not yet recruiting 1 9 Months 160 Naser Morina, PhD, Sonja Weilenmann, PhD 2020-09-05
BAC to the PAST: BCG Against Covid-19 for Prevention and Amelioration of Severity Trial Coronavirus disease 19 infection BCG Tokyo-172 alone Healthy volunteers accepted, Aged Adults (65-79 yrs), Elderly Adults (80 and over) Harvard Medical School Texas Medical Research Associates LLC US 2020-09-01 2021-11-30 BAC to the PAST, IRB20-1243, NCT04534803 Phase 3 Clinical Not yet recruiting 1 15 Months 2100 Megan B Murray, MD, ScD, Meredith Brooks, PhD, Ximena C Tovar 2020-09-22
SBHC: Data Collection on the Model Schools Pediatric Health Initiative at five SBHC Sites: COVID-19 Questionnaire Coronavirus disease 19 infection Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) St Michaels Hospital Canada 2019-04-30 2021-03-31 19-060, NCT04534595, SBHC Phase Not Applicable Recruiting 1 23 Months 1500 Sloane Freeman, MSc,MD,FRCPC 2020-09-04
Anti-inflammatory Effect of Low-Dose Whole-Lung Radiation for COVID-19 Pneumonia Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia radiotherapy (1 Gy) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto Mexicano del Seguro Social Mexico 2020-07-24 2021-04-05 NCT04534790, PI-2020-2858 Phase Not Applicable Recruiting 1 8 Months 30 Alejandro Olmos Guzman 2020-09-04
C-ARF: Expert Panel Statement for the Respiratory Management of COVID-19 Related Acute Respiratory Failure Coronavirus disease 19 infection, Respiratory failure Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) NMC Specialty Hospital United Arab Emirates 2020-09-04 2020-09-30 C-ARF, C19ARFstudy, NCT04534569 Phase Not Applicable No longer recruiting 1 40 Prashant Nasa 2020-09-10
NORCOVID: Oral Prednisone Regimens to Optimize the Therapeutic Strategy in Patients With Organizing Pneumonia Post-COVID-19 Coronavirus disease 19 infection, Viral pneumonia prednisone alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Vall D'Hebron 2020-09-07 2021-12-15 2020-003651-15, NCT04534478, NORCOVID Phase 4 Clinical Not yet recruiting 0 15 Months 120 Maria-Jesus Cruz, PhD 2020-09-06
Reshaping the Path of Vascular Cognitive Impairment (VCI) Amnesia, Babinski syndrome, Cerebrovascular disease, Cognitive disorder, Coronavirus disease 19 infection, Dysarthria, Ischemia, Movement disorder resistance exercise training alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of British Columbia Canada 2016-01-31 2021-12-31 H15-00972, NCT02669394 Phase Not Applicable Recruiting 1 71 Months 88 Charlie Goldsmith, PhD, Ging-Yuek Robin Hsiung, MD, PhD, Jennifer Davis, PhD, John Best, PhD, Kenneth Madden, MD, Roger Tam, PhD, Teresa Liu-Ambrose, PhD, PT, Thalia Field, MD, V5Z 1M9 2020-09-05
An investigator-led, multicenter, randomized study to evaluate nomacopan for the treatment of patients with COVID-19 pneumonia Coronavirus disease 19 infection, Viral pneumonia nomacopan alone Complement C5 factor inhibitor, Leukotriene BLT receptor antagonist Akari Therapeutics Plc US Phase Not Applicable Planned 1 60 2020-09-02
NRO-COV-50: Neurological rehabilitation outcome of the treatment of patients with COVID-19 disease Brain disease, Coronavirus disease 19 infection, Guillain Barre syndrome, Myopathy, Polyneuropathy, Stroke Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ludwig-Maximilians University of Munich Germany 2020-06-19 20-487, DRKS00022845, NRO-COV-50 Phase Not Applicable Recruiting 18 500 Andreas Bender, Gergana Drunin 2020-09-04
An expanded access, proof of principle program to evaluate nomacopan for the treatment of patients with COVID-19 pneumonia Coronavirus disease 19 infection, Viral pneumonia nomacopan alone Complement C5 factor inhibitor, Leukotriene BLT receptor antagonist Akari Therapeutics Plc US Phase Not Applicable Recruiting 1 2020-09-07
A trial to evaluate nomacopan for the treatment of patients with COVID-19 Coronavirus disease 19 infection nomacopan alone Complement C5 factor inhibitor, Leukotriene BLT receptor antagonist Akari Therapeutics Plc Africa 2020-12-31 Phase Not Applicable Planned 0 2020-09-02
A randomized study to evaluate nomacopan for the treatment of patients with COVID-19 pneumonia Coronavirus disease 19 infection, Viral pneumonia nomacopan alone Complement C5 factor inhibitor, Leukotriene BLT receptor antagonist Akari Therapeutics Plc Brazil 2020-12-31 Phase Not Applicable Planned 1 60 2020-09-02
A proof of principle clinical study to evaluate nomacopan in patients with COVID-19 pneumonia Coronavirus disease 19 infection, Viral pneumonia nomacopan alone Complement C5 factor inhibitor, Leukotriene BLT receptor antagonist Akari Therapeutics Plc Brazil Phase Not Applicable No longer recruiting 1 2020-09-02
Evaluation of slow release mucoadhesive paste of 'MUCODENTOL' in oral vestibule on symptoms of COVID-19 disease in hospital staff Coronavirus disease 19 infection Mucodentol alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Lorestan University Khorraman Pharmacy Iran 2020-05-09 2020-09-05 IR.LUMS.REC.1399.013, IRCT20090304001739N3 Phase 2 Clinical Completed 1 3 Months 1600 Ebrahim Fallahi, Sepideh Vahabi, Sepideh vahabi 2020-09-20
Effects of two products containing Noscapine on COVID-19 Coronavirus disease 19 infection Noscough alone, opioucough alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mashhad University of Medical Sciences Iran 2020-09-22 IR.MUMS.REC.1399.283, IRCT20180103038199N3 Phase 2 Clinical Recruiting 1 120 Vahid Reza Askari 2020-09-22
An observational, retrospective Italian survey study to determine the usefulness of hydroxychloroquine in the prevention of COVID-19 in patients under treatment for dermatological and rheumatological diseases Coronavirus disease 19 infection hydroxychloroquine alone Universita degli Studi di Napoli Federico II Italy Phase Not Applicable Status not specified 1 66 2020-09-02
Effects of an online mindfulness-based intervention on quality of life and psychological symptoms in novel coronavirus pneumonia (COVID-19) patients in China: a randomized, controlled trial Coronavirus disease 19 infection, Psychiatric disorder, Sleep disorder Mindfulness-based interventions (MBIs) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chinese Academy of Medical Sciences & Peking Union Medical College China ChiCTR2000037524 Phase 0 Clinical Not yet recruiting 1 1600 Mingyu Si, Xiaoyou Su 2020-09-05
RNB COVID-19: Effect of Allo-vedic Preparation Raj Nirwan Bati (RNB) on Severe COVID-19 Patients Coronavirus disease 19 infection Raj Nirwan Bati alone, allopathic treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Uttar Pradesh University of Medical Sciences India 2020-08-31 CTRI/2020/08/027467, RNB COVID-19 Phase 3 Clinical Not yet recruiting 1 40 Dr Raj Kumar 2020-09-04
COVID-IHPBA: Outcomes of liver and pancreatic caner surgery during the COVID-19 pandemic Coronavirus disease 19 infection, Surgical procedure hepatobiliary surgery alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tata Memorial Hospital India, US, Ireland, Germany, France 2020-08-31 COVID-IHPBA, CTRI/2020/08/027466 Phase Not Applicable Not yet recruiting 5 1000 Shailesh V Shrikhande 2020-09-04
SARS-CoV-2 quick analysis in breath device Coronavirus disease 19 infection breath analysis test (BAT) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto De Tecnologia Do Parana of Brazil Brazil 2020-08-31 35555720.7.0000.5225, 4.234.085, RBR-72bg24, U1111-1257-4565 Phase Not Applicable Not yet recruiting 1 3000 Ana Paula Gori Palka, Meila Bastos de Almeida 2020-09-04
A Clinical Study to Evaluate MW33 Injection Coronavirus disease 19 infection MW-33 alone COVID19 Spike glycoprotein inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Mabwell (Shanghai) Bioscience Co Ltd Shanghai Public Health Clinical Center China 2020-08-07 2020-12-31 MW33-2020-CP101, NCT04533048 Phase 1 Clinical No longer recruiting 1 4 Months 42 Hongzhou LU 2020-09-14
COVID-19 Treatment in South Africa Coronavirus disease 19 infection Variable regimens including artesunate + amodiaquine combination tablet (malaria), DNDi/sanofi-aventis , favipiravir , nitazoxanide , paracetamol , pyronaridine + artesunate (oral), Medicines for Malaria Venture/Shin Poong/WHO , sofosbuvir + daclatasvir RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Shin Poong Pharmaceutical Co Ltd Medicines for Malaria Venture South Africa 2020-09-03 2021-01-31 NCT04532931, SP-PA-COV-202 Phase 2 Clinical Recruiting 1 4 Months 250 Farouk Chughlay, MD, Francois Venter, PhD, Nomathemba Chandiwana, Sarah Arbe-Barnes, PhD 2020-09-09
Nasal Wash and Gargle to Mitigate COVID-19 Coronavirus disease 19 infection nasopharyngeal saline wash alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Health and Family Welfare Department of Government of West Bengal, M R Bangur Hospital India 2020-09-04 CTRI/2020/08/027465 Phase 1/Phase 2 Clinical Not yet recruiting 1 70 UDAY SANKAR CHATTERJEE 2020-09-14
Prevalence of COVID-19 Antibodies Kingman AZ Coronavirus disease 19 infection VITROS anti-SARS-CoV-2 IgG test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kingman Regional Medical Center US 2020-09-28 2020-12-28 KRMC 0205, NCT04533360 Phase Not Applicable Not yet recruiting 0 3 Months 3000 Anthony J Santarelli, PhD, John Ashurst, John V Ashurst, DO 2020-09-16
A Double-blind, Placebo-controlled Study to Assess the Efficacy and Safety of Oral Tafenoquine Versus Placebo in Patients With Mild-to-Moderate COVID-19 Disease Coronavirus disease 19 infection tafenoquine (oral tablet, malaria), 60° Pharmaceuticals/United States Army/Biocelect alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) 60° Pharmaceuticals LLC Peachtree BioResearch Solutions Inc 2020-10-31 2021-02-28 NCT04533347, TQ 2020_06 Phase 2 Clinical Not yet recruiting 0 4 Months 275 Geoffrey Dow, PhD 2020-09-12
Study for predicting hypoxemia in COVID 19 patients on the basis of HRCT thorax findings with correlating the CT findings with SpO2 levels Coronavirus disease 19 infection, Hypoxia High-resolution CT (HRCT) alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kalinga Institute of Medical Sciences India 2020-08-31 CTRI/2020/08/027500 Phase Not Applicable Not yet recruiting 1 1000 Ajay Sharawat, Dr Kamal Kumar Sen 2020-09-03
Measures for COVID-19 in psychiatry Coronavirus disease 19 infection Tohoku University Graduate School Of Medicine Japanese Ministry of Health, Labor and Welfare Japan 2020-09-01 UMIN000041557 Phase Not Applicable Not yet recruiting 1 150 Hiroaki Tomita 2020-09-03
C-SMART (Arm 4): COVID-19 prevention and treatment in cancer arm 4: treatment among cancer patients with severe COVID-19 infection Coronavirus disease 19 infection, Viral pneumonia lenzilumab alone GM-CSF ligand inhibitor, Immunoglobulin G1 modulator, Immunoglobulin kappa modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Peter MacCallum Cancer Centre Australian Government Australia 2020-09-01 2021-12-01 ACTRN12620000844943, ANZCTR380424, C-SMART (Arm 4), U1111-1256-8488 Phase 3 Clinical Not yet recruiting 5 15 Months 72 Michelle Yong, Monica Slavin, Ronan Burder 2020-09-03
Biocontainment Device for Aerosol Generating Procedures Coronavirus disease 19 infection Biobox biocontainment-aerosol evacuation system (National Flag) alone, rapid sequence intubation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Pennsylvania Drexel University US 2020-09-30 2020-12-31 843373, NCT04532112 Phase Not Applicable Not yet recruiting 1 3 Months 150 Josh Atkins, MD PhD, Josh Atkins, Md, PhD, Liz Beothy, Michael A Kohanski, MD PhD, Michael A Kohanski, MD, PhD, Mitch Weinstein, MD 2020-09-01
Role of siddha medicine in the management of covid -19 Coronavirus disease 19 infection Variable regimens including >Thaleesadhi vadagam Mathirai , Adathodai manapagu , Amukkara Chooranam Mathirai , Brammanandha bairavam , Kaba Sura Kudineer Chooranam Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Indian Medicine and Homoeopathy India 2020-09-05 CTRI/2020/08/027499 Phase 2 Clinical Not yet recruiting 1 20 DrASuganya 2020-09-03
To identify the pathogenesis of COVID-19 at different stages with the help of Ayurveda Coronavirus disease 19 infection Shat - kriya kala alone, Vikar vighata - bhava, abhava ( Nidana , dosha , dushya paradigm ) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Ayurveda India 2020-09-06 CTRI/2020/08/027494 Phase Not Applicable Not yet recruiting 1 75 Dr Sisir Kumar Mandal, Dr Tanuja Nesari 2020-09-02
therapeutic effect of Rosa Damascena extract in treatment of COVID-19 Coronavirus disease 19 infection Rosa Damascena alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Semnan University of Medical Sciences Iran 2020-08-22 IR.SEMUMS.REC.1399.106, IRCT20200402046917N1 Phase Not Applicable Recruiting 1 20 Akram alizadeh, Maliheh Ghadir 2020-09-02
'COVID-19: Hotspot hospital ?- Epidemiological analysis time shifted antibody tests of hospital employees' Coronavirus disease 19 infection antibody test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Vestische Caritas-Kliniken GmbH Germany 2020-06-15 2020-478-f-S, DRKS00022941 Phase Not Applicable Recruiting 0 3000 Anke Hildebrandt 2020-09-12
Benefits of Siddha medicines in covid-19 positive patients Coronavirus disease 19 infection Adathodaimanapagu alone, AmukkaraChooranamMathirai alone, Brammanandhabairavam alone, KabaSuraKudineerChooranam alone, Thaleesadhivadagam alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Central Council for Research in Siddha India CTRI/2020/08/027491 Phase 2 Clinical Not yet recruiting 1 20 DrVVikramkumar, Sathya Rajeshwaran 2020-09-02
Growth Hormone in Obese Cases With COVID-19 Coronavirus disease 19 infection, Obesity recombinant growth hormone alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) ClinAmygate Egypt 2020-10-26 NCT04532554, PR0015 Phase 4 Clinical Terminated 2 Emad R Issak, MD 2020-09-17
NEPSycon-COVID: Neurological manifestations of COVID-19 Coronavirus disease 19 infection Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) NHS NIHR Clinical Research Network China 2020-09-10 CTRI/2020/08/027490, NEPSycon-COVID Phase Not Applicable Not yet recruiting 1 200 Netravathi M, Ravi Vasanthapuram 2020-09-04
Mental health status, adjustment strategies due to covid19 pandemic and related factors Coronavirus disease 19 infection Adolescents (13-17 yrs), Young Adults (18-44 yrs) Kalinga Institute of Medical Sciences India 2020-09-06 CTRI/2020/08/027492 [ Phase Not Applicable Not yet recruiting 1 400 Jayanti MIshra 2020-09-14
A phase I clinical study of new COVID-19 vaccine for the potential treatment of COVID-19 infection Coronavirus disease 19 infection new COVID-19 vaccine alone Vaccitech Ltd UK Government Phase 1 Clinical Planned 0 2020-09-01
A Study Looking at the Effectiveness and Safety of a COVID-19 Vaccine in South African Adults Coronavirus disease 19 infection NVX-CoV2373 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Novavax Inc Bill & Melinda Gates Foundation South Africa 2020-08-17 2021-11-30 2019NCOV-501, NCT04533399 Phase 2b Clinical Recruiting 6 15 Months 2904 Gregory M. Glenn, Rani Naidoo, Shabir A Madhi, MBBCH, PhD, Vivek Shinde, MD, MPH 2020-09-08
COVID-19 Testing Sample Acquisition Throughput and Efficiency (HexapodBooth) Coronavirus disease 19 infection Hexapod personal protective booth alone, nasal swab test alone Healthy volunteers accepted Massachusetts General Hospital US 2020-03-01 2020-09-30 NCT04532411, QI INITIATIVE Phase Not Applicable No longer recruiting 0 7 Months 25000 Kristian R. Olson 2020-09-03
Taste and Smell Impairment in Critically Ill COVID-19 Patients Coronavirus disease 19 infection, Dysomia, Taste disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sisli Etfal Hospital Turkey 2020-09-01 2020-09-20 3334-02, NCT04532632 Phase Not Applicable Recruiting 1 40 Pinar Ay Sayin, mustafa altinay, pınar ay sayın 2020-09-09
PICS-COVID: Post-Intensive Care outcomes of patients with Corona virus Disease 2019 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Hospital Organization, Tokyo Medical Center Nestle Health Science Japan 2020-09-01 PICS-COVID, UMIN000041276 Phase Not Applicable Not yet recruiting 1 100 Junji Hatakeyama 2020-09-03
Leflunomide for the Treatment of Severe COVID-19 in Patients With a Concurrent Malignancy Cancer, Coronavirus disease 19 infection, Multiple myeloma, Respiratory distress syndrome leflunomide alone, standard of care alone, Variable regimens including dexamethasone , leflunomide , remdesivir , tocilizumab COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, Dihydroorotate dehydrogenase inhibitor, Protein tyrosine kinase inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) City of Hope Medical Center National Cancer Institute US 2020-09-18 2022-09-18 20291, NCI-2020-05746, NCT04532372, P30CA033572 Phase 1/Phase 2 Clinical Not yet recruiting 0 24 Months 30 Sanjeet S Dadwal, Sanjeet S. Dadwal 2020-09-07
A phase I/II, multi-national trial to evaluate DXP-604 in patients with mild to moderate COVID-19 Coronavirus disease 19 infection DXP-604 alone COVID19 Spike glycoprotein modulator BeiGene Co Ltd Phase 1/Phase 2 Clinical Planned 0 2020-09-03
Investigation for clinical utility of diagnostic reagents for COVID-19 Coronavirus disease 19 infection PCR testing alone, antigen testing alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Fujirebio Inc Japan 2020-09-01 UMIN000041402 Phase Not Applicable Not yet recruiting 1 300 Fumio Otsuka, Hideharu Hagiya 2020-09-03
Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2/COVID-19) Neutralizing Antibody in Healthy Participants Coronavirus disease 19 infection DXP-593 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) BeiGene Co Ltd Australia 2020-09-08 2020-12-31 BGB-DXP593-101, NCT04532294 Phase 1 Clinical Recruiting 2 3 Months 30 BeiGene, Zhen Yao 2020-09-16
Effect of blood thinning medicine in COVID-19 infection Coronavirus disease 19 infection Aspirin alone, standard of care  alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Medical Sciences India 2021-06-15 CTRI/2020/08/027503 Phase 2 Clinical Not yet recruiting 1 60 Dr Souvik Maitra 2020-09-03
Evaluation of safety and efficacy of T-AYU-HM premium and onion steam vaporization/nebulization in COVID-19 patients Coronavirus disease 19 infection T-AYU-HM Premium  alone, onion steam vaporization/nebulization alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) ATBU Harita Pharmaceuticals Private Ltd. India 2020-09-14 CTRI/2020/08/027477 Phase 2 Clinical Not yet recruiting 1 Dr Atul M Desai, Dr Hemshree Desai 2020-09-14
A Randomized Controlled Trial Of An Immunomodulator Mycobacterium w In Mild To Moderate COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia immunomodulator mycobacterium w alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Cadila Pharmaceuticals Ltd India 2020-09-01 CTRI/2020/08/027475 Phase 3 Clinical Not yet recruiting 1 30 Dr Shweta Ram Chandankhede 2020-09-03
Oxygen requirement in COVID patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sri Ramachandra University India 2020-08-31 CTRI/2020/08/027460 Phase Not Applicable Not yet recruiting 1 100 Priyadarshini Varadaraj 2020-09-03
To study about the outcome of COVID-19 on Diabetes patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sri Ramachandra Institute of Higher Education and Research India 2020-09-01 CTRI/2020/08/027459 Phase Not Applicable Not yet recruiting 1 200 DR Aiswarya M Nair 2020-09-03
Comparison two types of artificial respiration in severe COVID-19 patients Coronavirus disease 19 infection, Respiratory distress syndrome Airway Pressure Release Ventilation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Medical Sciences India 2020-09-10 CTRI/2020/08/027502 Phase Not Applicable Not yet recruiting 1 216 Dr Souvik Maitra 2020-09-07
Anesthesia practices and safety of caregivers during the covid 19 pandemic Coronavirus disease 19 infection Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Max Super Speciality Hospital India 2020-09-01 CTRI/2020/08/027470 Phase Not Applicable Not yet recruiting 1 300 Nambiath Sujata 2020-09-03
Laboratory predictors and covid Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sri Ramachandra Medical College, Hospital & Research institute India 2020-08-31 CTRI/2020/08/027458 Phase Not Applicable Not yet recruiting 1 850 Dr Vaasanthi 2020-09-03
A survey to understand the opinion among doctors regarding usage of personal protective equipment Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Karnataka Institute of Medical Sciences India 2020-09-01 CTRI/2020/08/027469 Phase Not Applicable Not yet recruiting 1 1000 Milon Vasant Mitragotri 2020-09-03
Covid Nuvastatic: To Evaluate Safety and Efficacy of Nuvastatic as an Immunomodulator Adjuvant Therapy in COVID-19 Patients Coronavirus disease 19 infection Nuvastatic alone, standard care of treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Natureceuticals Sdn Bhd India 2020-09-01 2020-09-30 BIAG-CSP-037, CTRI/2020/08/027501, Covid Nuvastatic, NCT04542447 Phase 2 Clinical Recruiting 1 1 Month 10 Dr Shruti Saini, Sanjay Vinaik 2020-09-11
HRCT chest imaging in pediartic, adult and geriatric patients with COVID-19 infection Coronavirus disease 19 infection Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kalinga Institute of Medical Sciences India 2020-09-01 CTRI/2020/08/027468 Phase Not Applicable Not yet recruiting 1 900 Dr Mayank Goyal, DrCol Kamal K Sen 2020-09-03
BG-CoV: Association of COVID-19 severity with blood group antigens Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Medical Sciences India 2020-09-01 BG-CoV, CTRI/2020/08/027471 Phase Not Applicable Not yet recruiting 1 200 Diptiranjan Rout 2020-09-03
A medical records based research on the establishment of a precise treatment system for novel coronavirus pneumonia (COVID-19) from the perspective of ''damp-and-heat epidemic'' Coronavirus disease 19 infection traditional chinese medicine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shanghai Traditional Chinese Medicine Hospital Shanghai shen-kang hospital clinical development center China 2020-10-01 2023-10-01 ChiCTR2000037342 Phase Not Applicable Not yet recruiting 1 36 Months 300 Shi Kehua 2020-09-02
Respiratory Syncytial Virus Infection May be More Dangerous in Neonate Coronavirus disease 19 infection, Respiratory syncytial virus infection Bio-Speedy qPCR detection kit alone, Bosphore Respiratory Pathogens Panel Kit V4 alone, biological sampling alone Newborn Infants (up to 5 months) Dr. Behcet Uz Children's Hospital Turkey 2020-03-01 2020-08-31 2020/522, NCT04531735 Phase Not Applicable No longer recruiting 1 6 Months 28 Senem Alkan Özdemir 2020-09-02
Camostat and Artemisia Annua Versus Placebo in COVID-19 Outpatients Coronavirus disease 19 infection, Viral pneumonia Artemisia annua alone, camostat mesylate alone Serine protease inhibitor, Transmembrane serine protease 2 inhibitor, Trypsin inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto Nacional de Ciencias Medicas y Nutricion Hospital General Dr. Manuel Gea González, Hospital General de Mexico, Instituto Nacional de Cardiologia Ignacio Chavez Mexico 2020-09-30 2021-02-28 3421, NCT04530617 Phase 2 Clinical Not yet recruiting 1 5 Months 360 David Kershenobich Stalnikowitz, MD, Jose G Gotes Palazuelos, MD 2020-09-11
Immune Cell Subgroups in Covid 19 Patients Coronavirus disease 19 infection, Lymphocytopenia, Respiratory failure Flow cytometric analysis alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Istanbul Training and Research Hospital Turkey 2020-08-15 2020-09-15 COVID CELL, NCT04531319 Phase Not Applicable Recruiting 1 1 Month 60 Tahir Talat Yurttas, MD, Ufuk Oguz Idiz, Assoc. Prof 2020-09-01
Timing of Corticosteroids in COVID-19 Coronavirus disease 19 infection dexamethasone alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) ClinAmygate Egypt 2020-08-26 2020-11-01 NCT04530409, PR0012 Phase 4 Clinical Recruiting 2 2 Months 450 Emad R Issak, Emad R Issak, MD, Emad Roushdy, Dr 2020-09-17
Efficacy and Safety of Recovered Covid-19 Plasma Transfusion to Covid-19 Severly Ill Patients Coronavirus disease 19 infection recovered Covid-19 patient plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) South Valley University Egypt 2020-05-29 2020-09-01 NCT04530370, OSSAMAHAMDYRESEARCHER7 Phase 0 Clinical Recruiting 1 3 Months 30 Gad S Gad, MD, Gad s Gad, MD, Ossama Hamdy Salman, ossama h salman, MD,PhD 2020-09-01
Outpatient Use of Ivermectin in COVID-19 Coronavirus disease 19 infection ivermectin alone Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Temple University US 2020-10-01 2021-12-31 1285242, NCT04530474 Phase 3 Clinical Not yet recruiting 0 15 Months 200 Derek Isenberg, MD, Nina Gentile, MD 2020-09-01
Back to School COVID-19 Simulation Study Coronavirus disease 19 infection Face mask alone Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Hospital for Sick Children Canada 2020-08-10 2020-12-31 1000071861, NCT04531254 Phase Not Applicable No longer recruiting 1 4 Months 240 Michelle Science 2020-09-02
EPICOVID-PAHANG: Epidemiological study of COVID-19 in Pahang Coronavirus disease 19 infection Malaysia 2020-08-28 2020-12-31 56085, EPICOVID-PAHANG, NMRR-20-1825-56085 Phase Not Applicable Status not specified 1 4 Months Dr Che Asiah binti Taib, Dr muhammad 'adil bin zainal abidin 2020-09-01
Drug utilization for Covid-19 Coronavirus disease 19 infection International Islamic University Malaysia Malaysia 2020-10-01 2021-09-30 56013, NMRR-20-1823-56013 Phase Not Applicable Status not specified 1 12 Months Assoc Prof Dr Che Suraya Haji Mohd Zin 2020-09-01
RESIST: Clinical Trial of Efficacy, Safety, and Immunogenicity of Gam-COVID-Vac Vaccine Against COVID-19 Coronavirus disease 19 infection Sputnik V alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Health Ministry of the Russian Federation Collaborator City of Moscow, Crocus Medical B.V Russian Federation 2020-09-07 2021-05-01 04-GAM-COVID-VAC-2020, NCT04530396, RESIST Phase 3 Clinical Recruiting 24 7 Months 40000 Anastasia Andezhanova, MD, Boris Rodionov, MD, Ekaterina Medunitzina, MD, Elena Klimova, MD, Elena Nurmukhametova, MD, PhD, Elena Smolyarchuk, MD, PhD, Georgy Anikin, MD, Igor Sychev, MD, Inna Dolzhikova, PhD, Irina Gagarina, MD, Irina Iskakova, MD, Irina Shestakova, MD, Konstantin Zakharov, MD, Lola Morozova, MD, Marina Ivzits, MD, Marina Rusanova, MD, Nadezhda Berdnikova, MD, Natalia Shartanova, MD, Sergey Fitilev, MD, Taisiya Ivanushkina, MD, Tatiana Shimonova, MD, Tatyana Vylegzhanina, MD 2020-09-20
Glycemic Control Among Children and Adolescents With Type 1 Diabetes During COVID-19 Pandemic in Egypt Coronavirus disease 19 infection, Insulin dependent diabetes Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Ain Shams University Egypt 2020-07-07 2020-08-31 FMASU P66/2020, NCT04531111 Phase Not Applicable Recruiting 1 1 Month 150 Khadiga Eltonbary, Yasmine Ehenawyl, Yasmine Elhenawy 2020-09-01
Serological Profile of SARS CoV2 in Patients With Systemic Diseases Behcets disease, Coronavirus disease 19 infection, Myopathy, Rheumatoid arthritis, Sarcoidosis, Sjoegrens syndrome, Spondylarthritis, Systemic lupus erythematosus RT-PCR alone, biological sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopital Militaire Principal d'instruction de Tunis Tunisia 2020-06-01 2021-01-31 NCT04530461, UR17DN02-002 Phase Not Applicable Recruiting 1 8 Months 200 Faida Ajili, MD, Rim Dhahri, MD, Sameh Sayahi, MD, faida agili 2020-09-03
PEP-CoV: PEP Flute-selfcare in COVID-19 Coronavirus disease 19 infection, Respiratory disease COPD assessment test alone, daily text messaging alone, positive expiratory pressure flute alone, video guidance alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bispebjerg Hospital HS Hvidovre Hospital Denmark 2020-09-01 2021-04-30 0211-00023B, NCT04530435, PEP-CoV Phase Not Applicable Not yet recruiting 1 8 Months 400 Annette Mollerup, PhD, Berit L. Heitmann, Professor, Ph.D, Sofus C. Larsen, PhD 2020-09-02
PROTECT-COVID-19-US: Prevention of Severe SARS-CoV-2 Infection in Hospitalized Patients With COVID-19 Acute lung injury, Coronavirus disease 19 infection, Lung disease conestat alfa alone, standard of care alone Complement C1s subcomponent inhibitor, Kallikrein modulator, Mannan-binding lectin serine protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Pharming Technologies BV US 2020-09-15 2021-03-31 C1 6201, NCT04530136, PROTECT-COVID-19-US Phase 2 Clinical Not yet recruiting 0 6 Months 120 Anurag Relan, MD, Jonathan Bernstein, MD, Leisa Waynick, BSBA 2020-09-03
COVID-19 Saliva Test Research Study Coronavirus disease 19 infection Chronomics test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chronomics Ltd UK 2020-06-29 2020-09-29 283560, NCT04531501 Phase Not Applicable Recruiting 2 3 Months 400 Hannah Howlett, Janet Forkes, Sana Wahid 2020-09-02
SAINT-PERU: Randomized, phase IIa clinical trial to compare the efficacy of ivermectin versus placebo to obtain negative PCR results in patients with early phase COVID-19 Coronavirus disease 19 infection ivermectin alone Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidad Peruana Cayetano Heredia Peru 2020-09-07 PER-034-20, SAINT-PERU Phase 2a Clinical Not yet recruiting 1 68 Carlos Chaccour Díaz, César Cárcamo Cavagnaro, César Ugarte Gil, German Javier Malaga Rodrìguez, Germán Málaga Rodríguez, Hansel Kevin Mundaca Hurtado, PATRICIA JANNET GARCÍA FUNEGRA, Patricia Hilda León Paredes, Patricia Jannet García Funegra 2020-09-02
A phase I clinical trial of viral protease inhibitor (COVID-19), University of Alberta in combination with remdesivir for COVID-19 treatment Coronavirus disease 19 infection GC-376 plus remdesivir COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1a inhibitor, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator University of Alberta Phase 1 Clinical Planned 0 2020-09-15
AUNA 20-01: Phase II study of efficacy and safety of plasma from convalescent patients with COVID-19 in patients with moderate disease Coronavirus disease 19 infection convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Oncosalud S.A.C. Peru 2020-07-06 AUNA 20-01, PER-031-20 Phase 2 Clinical Not yet recruiting 1 50 Alejandro DALY TURCKE, Alfredo Eric Goytendia Cortez, Antonio Alfredo Carrasco Yalan, INA NOELIA PÉREZ HUAYNALAYA, Ina Noelia Pérez Huaynalaya, Joseph Arturo Pinto Oblitas, Maria Consuelo Requena Medina, Victor Romario Pizarro Herrera 2020-09-12
A global, randomised, placebo-controlled Phase II trial of LYT-100 for the treatement of serious respiratory complications linked to inflammation and fibrosis that persist following the resolution of SARS-CoV-2 (COVID-19) infection Coronavirus disease 19 infection, Fibrosis, Respiratory disease, Respiratory tract inflammation deupirfenidone alone PDGF receptor antagonist, TGF beta receptor antagonist, p38 MAP kinase inhibitor PureTech Health Plc 2020-09-30 Phase 2 Clinical Planned 0 2020-08-31
Reactogenicity, Safety and Immunogenicity of QazCovid-in COVID-19 Vaccine Coronavirus disease 19 infection QAZCOVID-IN alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Research Institute for Biological Safety Problems, RIBSP Ministry of Health of the Republic of Kazakhstan Kazakhstan 2020-09-01 2021-04-30 NCT04530357, QAZCOV-I/II-01/2020 Phase 1/Phase 2 Clinical Recruiting 1 8 Months 244 Berik Khairullin, PhD, Gulbanu Sarsenbayeva, MB, Ilyas Kulmagambetov, PhD, Kunsulu Zakarya, PhD 2020-09-07
The Effect of Melatonin and Vitamin C on COVID-19 Coronavirus disease 19 infection ascorbic acid alone, melatonin alone Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Lancaster General Hospital US 2020-09-18 2021-12-01 2020-68, NCT04530539 Phase Not Applicable Not yet recruiting 1 14 Months 150 Alison Mercier, MD, Ca Forney, Cathleen Forney, Corey Fogleman, Corey Fogleman, MD, Daniel Farrell, MD, Donna Cohen, MD, Jennifer Rutz, MD, Tawnya Vernon 2020-09-16
RESPOnD: A clinical trial is to investigate TYME-19 for safety and efficacy in recently diagnosed, symptomatic COVID-19 patients Coronavirus disease 19 infection TYME-19 alone COVID19 Spike glycoprotein inhibitor Tyme Technologies Inc Massachusetts General Hospital, Weill Medical College of Cornell University RESPOnD Phase Not Applicable Planned 0 2020-09-18
A phase I clinical trial of DIOS-CoVax2 for the potential treatment of COVID-19 infection Coronavirus disease 19 infection DIOS-CoVax2 alone DIOSynVax Ltd, University of Cambridge Technology Strategy Board, University Hospital Southampton NHS Foundation Trust UK Phase 1 Clinical Planned 1 2020-08-31
A Phase I/II clinical trial of VBI-2902 for the treatment of Coronavirus disease 19 infection Coronavirus disease 19 infection VBI-2902 alone COVID19 Spike glycoprotein modulator VBI Vaccines Inc 2020-12-31 Phase 1/Phase 2 Clinical Planned 0 2020-09-02
Phase I Trial of a Recombinant SARS-CoV-2 Vaccine (Sf9 Cell) Coronavirus disease 19 infection SARS-CoV-2 vaccine (Sf9 Cell, COVID-19), Jiangsu Province Centers for Disease Control and Prevention alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry Jiangsu Province Centers for Disease Control and Prevention West China Hospital China 2020-08-28 2021-08-28 ChiCTR2000037518, JSVCT098, NCT04530656 Phase 1 Clinical Not yet recruiting 1 12 Months 168 Fanyue Meng, Doctor, Fengcai Zhu, Doctor, Siyue Jia, PhD, Wei Wang 2020-09-07
SENTINEL: Selective Estrogen Modulation and Melatonin in Early COVID-19 Coronavirus disease 19 infection melatonin plus toremifene Estrogen receptor modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cleveland Clinic Foundation US 2020-09-30 2021-09-30 20-842, NCT04531748, SENTINEL Phase 2 Clinical Not yet recruiting 1 12 Months 390 Kylie Phillips, Reena Mehra, MD, Samantha Wells 2020-09-02
Coronavirus-Induced Acute Kidney Injury: Prevention Using Urine Alkalinization Coronavirus disease 19 infection, Renal injury sodium bicarbonate alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) West Virginia University US 2020-09-30 2021-03-31 NCT04530448, WVU PROTOCOL #2005006707 Phase 4 Clinical Not yet recruiting 1 6 Months 40 Ankit Sakhuja, Ankit Sakhuja, MD, Lisa Fornaresio, PhD 2020-09-18
Effects of Sevoflurane on Extravascular Lung Water and Pulmonary Vascular Permeability in Patients With ARDS Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure AnaConDa-S, Sedana Medical alone, remifentanil plus sevoflurane Opioid receptor mu agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopital de Bicetre France 2020-11-30 2022-11-30 BICETREH, NCT04530188 Phase 3 Clinical Not yet recruiting 1 24 Months 68 Christopher Lai, principal investigator, Christopher lai, MD, Xavier Monnet, MD, PhD 2020-09-02
Efficacy of Sofosbuvir Plus Ledipasvir in Egyptian Patients With COVID-19 Compared to Standard Treatment Coronavirus disease 19 infection, Viral pneumonia Variable regimens including ceftriaxone , enoxaparin sodium , methylprednisolone , sofosbuvir + ledipasvir Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Egypt 2020-04-15 2020-07-23 14, NCT04530422 Phase 3 Clinical Completed 1 3 Months 250 Mohamed Abdelsalam El-Gohary 2020-09-03
Cytokine Status of Covid-19 Patients Coronavirus disease 19 infection, Lymphocytopenia, Respiratory failure flow cytometry alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Istanbul Training and Research Hospital Turkey 2020-09-01 2020-10-15 COVID CYTOKINE, NCT04531345 Phase Not Applicable Not yet recruiting 1 1 Month 50 Tahir Talat Yurttas, MD, Ufuk Oguz Idiz, Assoc. Prof 2020-09-01
CORE Study COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto D'Or de Pesquisa Switzerland, Brazil, UK 2020-03-02 2021-09-30 29496920.8.0000.5262, NCT04531202 Phase Not Applicable Recruiting 3 18 Months 2000 Fernando Bozza, phD 2020-09-02
COVID-19 In-vitro Diagnostic Test and Androgen Receptor Gene Expression Coronavirus disease 19 infection COVID-19 androgen sensitivity test alone Healthy volunteers accepted, Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of California Irvine Applied Biology Inc US 2020-08-13 2021-08-31 2020-5907, NCT04530500 Phase Not Applicable Recruiting 2 12 Months 200 Natasha Mesinkovska, MD, PhD 2020-09-02
NEBUHEPA: Nebulized Heparin in Severe Acute Respiratory Syndrome COVID-19 Coronavirus disease 19 infection, Inflammatory disease, Lung disease, Viral pneumonia enoxaparin sodium plus heparin sodium Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Clinica San Camilo Argentina 2020-06-01 2021-06-01 CSANCAMILO, NCT04530578, NEBUHEPA Phase 4 Clinical Recruiting 1 12 Months 200 ALICIA B VILASECA, DR, RUBEN F BARBERA, DR, Ruben F Barbera, DR 2020-09-02
Defibrotide Therapy for SARS-CoV2 (COVID-19) Acute Respiratory Distress Syndrome (ARDS) Coronavirus disease 19 infection, Lung disease, Respiratory distress syndrome, Viral pneumonia defibrotide (iv, veno-occlusive disease), Gentium alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Michigan Jazz Pharmaceuticals plc US 2020-09-30 2021-07-31 HUM00182089, NCT04530604 Phase 1 Clinical Not yet recruiting 1 10 Months 12 Gregory Yanik, MD, Mary Maliarik, PhD 2020-09-03
A trial to evaluate adjuvanted peptide vaccine (microsphere formulation, COVID-19), University of Saskatchewan/VIDO-InterVac/ZYUS Life Sciences for the prevention of COVID-19 Coronavirus disease 19 infection adjuvanted peptide vaccine (microsphere formulation, COVID-19), University of Saskatchewan/VIDO-InterVac/ZYUS Life Sciences alone Government of Saskatchewan, VIDO-InterVac Canadian Government 2020-12-31 Phase Not Applicable Planned 0 2020-09-02
COVIDRIC: COVID-19 in Rheumatic Inflammatory Diseases Under Immuno-suppressive Drugs Coronavirus disease 19 infection, Rheumatoid arthritis, Spondylarthritis immuno-suppressive drug therapy alone, serological test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Montpellier Societe Francaise de Rhumatologie France 2020-10-20 2024-07-31 COVIDRIC, NCT04530682, RECHMPL20_0409, UF8074 Phase Not Applicable Not yet recruiting 1 45 Months 5000 Jacques MOREL, MD, PhD 2020-09-03
COVID-19 severity in Elderly people aged > 60 years Coronavirus disease 19 infection Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sri Ramachandra Institute of Higher Education and Research India 2020-08-30 CTRI/2020/08/027435 Phase Not Applicable Not yet recruiting 1 200 Dr Viswanathan P 2020-09-03
A Survey to Assess the Impact of the COVID-19 Pandemic and Resultant Lockdown Measures on Ongoing Clinical Trials in India Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) India 2020-09-06 CTRI/2020/08/027420, Survey-IND-01-2020 Phase Not Applicable Not yet recruiting 1 130 Jayanti Gupta, Rakesh Dadhania 2020-08-31
A case report to evaluate the efficacy of methylprednisolone in patients with immune-related pneumonitis and COVID-19 infection Coronavirus disease 19 infection, Pneumonia methylprednisolone alone Sociedade Beneficente Israelita Brasileira Hospital Albert Einsten Phase Not Applicable Status not specified 0 2 2020-09-01
Prevalence of and Factors Associated with Burnout among Philippine Radiation Oncology Residents During the COVID-19 Pandemic Coronavirus disease 19 infection Philippine General Hospital Philippines 2020-07-26 2020-08-09 PHRR200820-002847 Phase Not Applicable Completed 1 Aedrian A. Abrilla, Johanna Patricia Adevoso-Cañal, MD, MHA, MSc, Jose Miguel C. Callueng, MD 2020-09-01
Herd immunity level to COVID-19 as an indicator of the epidemic progression in Thailand Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) HRH Princess Chulabhorn College of Medical Science, Chulabhorn Royal Academy Thailand 2020-07-07 TCTR20200822003 Phase Not Applicable Recruiting 1 15000 Chirayu Auewarakul 2020-09-01
Offline versus online presentation: benefits and challenges during covid pandemic Coronavirus disease 19 infection Offline presentation alone, Online presentation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Manipal Academy of Higher Education Kasturba Medical College, Manipal India 2020-09-15 CTRI/2020/08/027418 Phase Not Applicable Not yet recruiting 1 225 Vijetha Shenoy Belle 2020-09-15
Covid-19 with hypertension is responsible for death of patients Coronavirus disease 19 infection, Hypertension Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gujarat Cancer Society Medical college hospital and research centre India 2020-08-31 CTRI/2020/08/027407 Phase Not Applicable Not yet recruiting 1 200 Dr Mahipalsinh Raol 2020-08-31
A retrospective assessment of risk factors for COVID- 19 in health care workers Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Lok Nayak Hospital, Maulana Azad Medical College India 2020-09-07 CTRI/2020/08/027403 Phase Not Applicable Not yet recruiting 1 90 DrSukhyanti Kerai 2020-09-01
Seroprevalence surveillance of covid-19 among population in Johar- 2020 Coronavirus disease 19 infection Jabatan Kesihatan Negeri Johar Malaysia 2020-09-01 NMRR-20-1814-55673 Phase Not Applicable Status not specified 1 Dr Jeyanthini a/p Sathasivam 2020-09-10
A retrospective study to evaluate cumulative incidence of Covid-19 and its treatment outcome, mortality and associated risk factors in lung cancer patients Coronavirus disease 19 infection, Lung tumor azithromycin plus hydroxychloroquine Hospital Universitario Infanta Leonor Spain Phase Not Applicable Status not specified 1 320000 2020-08-31
Realtion of Catalytic iron and Hepcidin with Poor Outcomes in COVID-19 patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) KEM Hospital and Research Center India 2020-09-07 CTRI/2020/08/027419 Phase Not Applicable Not yet recruiting 1 49 Dr Vipul Chakurkar 2020-08-31
An observational, retrospective study on the association between the use of angiotensin-converting enzyme inhibitors/angiotensinogen receptor blockers and in-hospital mortality of hypertensive patients diagnosed with COVID-19 pneumonia Coronavirus disease 19 infection, Hypertension, Viral pneumonia angiotensin-converting enzyme inhibitors alone, angiotensinogen receptor blockers alone Saglik bilimleri universtesi Phase Not Applicable Status not specified 0 74 2020-08-31
S-Nitrosylation Therapy of COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome S-nitrosothiol alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Japanese Ancestry University Hospitals of Cleveland Case Western Reserve University US 2020-10-31 2021-04-30 NCT04528771, STUDY20200453 Phase 1b Clinical Not yet recruiting 1 6 Months 21 James Reynolds, PhD, Olivia Giddings, MD, Rana Hejal, MD, Robert Schilz, DO, PhD 2020-09-01
A Case Report of Thrombosis and Bleeding as presentation of COVID-19 infection with polycythemia vera Bleeding, Coronavirus disease 19 infection, Polycythemia vera Sarawak General Hospital Malaysia 2020-08-25 NMRR-20-1803-56251 Phase Not Applicable Status not specified 1 Dr Chow Lai Chee 2020-09-09
The technical specification of precise drug therapy and the systematic study of novel Coronavirus inactivation procedure for biological samples Coronavirus disease 19 infection genetic testing alone Shanghai Jiao Tong University China 2020-10-01 2021-09-30 ChiCTR2000037078 Phase 0 Clinical Not yet recruiting 1 12 Months 100 guorong fan, zhenghua wu 2020-08-31
IVERCORCOVID19: Ivermectin to Prevent Hospitalizations in COVID-19 Coronavirus disease 19 infection ivermectin alone Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institute of Cardiology of Corrientes Argentina 2020-08-19 2021-01-31 IVERCORCOVID19, IVERCORCOVID19MSPICC, NCT04529525 Phase 2/Phase 3 Clinical Recruiting 1 5 Months 500 Angelina Bobadilla, Dra, Antonia C Aquino, Carolina N Martemucci, Claudia Campias, Claudia E Chaparro Campias, Diego Farizano, Eduardo Castillo Ruveda, Elba Meza, Fabian Plano, Dr, Fernando Achinelli, Dr, Gerardo Andino, Hector A Gugliermone, Jorge Ojeda, Dr, Juan E Segovia, Julio Vallejos, Dr, Maria Bangher, Dra, Maria F Medina, Maria G Aguirre, Maria M Vernengo, Natalia E Ruiz Diaz, Pablo Kawerin, Rodrigo Zoni, Dr, Silvana M Martinez, Silvina D Dellamea, Silvina Villamandos, Dra, Victor A Flores 2020-09-16
Our experience with emergency ophthalmic surgery at Hospital Kuala Lumpur (HKL) during the COVID-19 pandemi Coronavirus disease 19 infection, Ocular disease Hospital Kuala Lumpur Malaysia 2020-08-20 2020-12-31 NMRR-20-1790-56127 Phase Not Applicable Status not specified 1 4 Months Dr Seow Shu Yee 2020-09-09
Application of IL-18/IL-18BP in diagnosis and treatment of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection IL-18BP antagonist therapy alone Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shanghai Public Health Clinical Center China 2020-10-30 2022-10-30 ChiCTR2000036661 Phase 0 Clinical Not yet recruiting 1 24 Months 30 Mingquan Guo 2020-09-02
Palliative care expertise as an integral part of pandemic management (COVID-19) Coronavirus disease 19 infection Universitätsklinikum Freiburg, Klinik für Palliativmedizin Germany 2020-05-29 299/20, DRKS00022473 Phase Not Applicable Recruiting 1 30 Katharina Seibel 2020-08-31
Establishment of imaging diagnostic models for novel coronavirus pneumonia (COVID-19) and related brain injury based on artificial intelligence Coronavirus disease 19 infection, Viral pneumonia Huashan Hospital, Shanghai shen-kang hospital clinical development center China 2020-10-01 2022-09-30 ChiCTR2000036849 Phase 0 Clinical Not yet recruiting 1 24 Months 5000 Bo Yin 2020-08-31
Multi-center, Randomized, Double-Blind and Placebo-Controlled Clinical Trial on the Efficacy and Safety of Jinhua Qinggan Granules (JHQG) for the Treatment of COVID-19 Patient Coronavirus disease 19 infection, Viral pneumonia Jinhua Qinggan Granules alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Beijing Hospital of Traditional Chinese Medicine affiliated to Capital Medical University, University Of Karachi Pakistan 2020-04-24 2021-04-30 ChiCTR2000036871, ChiMCTR2000003697 Phase 4 Clinical Not yet recruiting 2 12 Months Prof. Dr M. Raza Shah T.I./Liu Qing Quan, Xin Li 2020-08-31
Convalescent Plasma for Treating Patients With COVID-19 Pneumonia Without Indication of Ventilatory Support Coronavirus disease 19 infection, Viral pneumonia convalescent plasma alone, standard treatment alone Instituto D'Or de Pesquisa Hospital do Coracao Brazil 2020-08-18 2020-12-31 34651120.8.0000.5249, NCT04528368 Phase 2 Clinical Recruiting 1 4 Months 60 Abel Costa Neto, MD, Eduardo M Rego, MD, PhD 2020-08-28
A case report of 18F-fluorodeoxyglucose uptake in patient with asymptomatic severe acute respiratory syndrome coronavirus 2 (coronavirus disease 2019) referred to positron emission tomography/computed tomography for non small cell lung cancer restaging Coronavirus disease 19 infection, Non-small-cell lung cancer, SARS coronavirus infection 18F-fluorodeoxyglucose alone, Positron emission tomography/computed tomography alone Male University of Turin Italy Phase Not Applicable Status not specified 1 1 2020-08-31
Presentation, Clinical Course and Patterns of Myocardial Damage Due to Viral Myocarditis Adenovirus infection, Coronavirus disease 19 infection, Enterovirus infection, Heart injury, Hepatitis B virus infection, Hepatitis C virus infection, Myocarditis, Parvovirus infection 12 lead ECG alone, ELIZA alone, PCR alone, cardiac MRI alone, coronary angiography alone, echocardiography alone, endomyocardial biopsy alone, immunohistochemistry alone, nucleic acid extraction alone, quantitative real-time PCR alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assiut University Egypt 2020-10-01 2021-03-01 NCT04527835, VIRAL MYOCARDITIS Phase Not Applicable Recruiting 1 5 Months 18 Amr Elbadry, lecturer, Amr yousif, professor, Ayman khairy, assistant professor, Ayman khairy, professor, Shery Asaad, Resident, Shery Asaad, resident, Shery Refaat Asaad 2020-09-03
QUICK study: A multicenter, retrospective, longitudinal, observational study about Quarantine and social Isolation for COVID-19 and its impact on Kawasaki disease Adenovirus infection, Coronavirus disease 19 infection, Gastrointestinal infection, Herpesvirus type 6 infection, Influenza virus infection, Kawasaki disease, Metapneumovirus infection, Respiratory syncytial virus infection, Respiratory tract infection, Skin infection, Streptococcus pyogenes infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Japanese Ancestry Fukuoka Children's Hospital, Kawasaki disease center Japan 2020-06-01 2020-08-10 QUICK study, UMIN000041579 Phase Not Applicable No longer recruiting 6 2 Months 4500 Kenji Furuno, Toshiro Hara 2020-09-02
Development of Ethical and Operational Guidelines for the Delivery of Surgical Care in a COVID-19 Referral Hospital Coronavirus disease 19 infection surgical care alone Philippine General Hospital Philippines 2020-06-01 2020-08-01 PHRR200820-002855 Phase Not Applicable No longer recruiting 1 2 Months Alvin B. Caballes, MD, MDE, MPP, Brent Andrew G. Viray, MD, MPM-HSD, Claudine Lukban, MD, Marie Carmela Lapitan, Maureen Villanueva, MD, Samantha Siahetong, MD 2020-08-31
Use of emergency medical services: experience 100 days after first case of COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Khon Kaen University Thailand 2020-08-21 TCTR20200822002 Phase Not Applicable Recruiting 1 545 Korakot Apiratwarakul 2020-08-31
THINC: Evaluation of the Efficacy and Safety of Treatments for Patients Hospitalized for COVID-19 Infection Without Signs of Acute Respiratory Failure, in Tunisia Bronchitis, Coronavirus disease 19 infection, Lower respiratory tract infection, Respiratory failure, Viral pneumonia usual standard treatment alone, Variable regimens including azithromycin , doxycycline hyclate , hydroxychloroquine , zinc Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Abderrahmane Mami Hospital Datametrix AG, Eshmoun Clinical Research Centre Tunisia 2020-05-15 2020-07-15 ECC2020-05, NCT04528927, THINC Phase 3 Clinical Terminated 1 2 Months Dr Jalila Ben Khelil 2020-09-02
PRESAGE: Study of Seroprevalence Vis-a-vis SARS-CoV2 and Correlation With Clinical Forms of COVID-19 in Patients Followed in Pneumology in the Cluster Area of the Grand-Est Region (Strasbourg University Hospital) Coronavirus disease 19 infection, Respiratory failure Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopitaux Universitaires de Strasbourg France 2020-09-30 2022-12-31 7879, NCT04528901, PRESAGE Phase Not Applicable Recruiting 1 27 Months 1080 Celine MASCAUX, Céline MASCAUX 2020-09-08
Response of Korean Medicine Hospital to COVID-19 Coronavirus disease 19 infection Healthy volunteers accepted Jaseng Hospital of Oriental Medicine Jaseng Medical Academy South Korea 2020-06-10 2020-08-10 JMA-CT-2020-01, NCT04529447 Phase Not Applicable Completed 1 2 Months 485 Jinho Lee, KMD, Ph.D. 2020-09-16
EARSATS-19: In-ear Measurement of Blood Oxygen Saturation in COVID-19 Follow-up Coronavirus disease 19 infection, Lung disease ear plug type pulse oximeter probe alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Imperial College London UK 2020-08-26 2020-08-26 285603, EARSATS-19, NCT04529408 Phase Not Applicable Recruiting 1 60 Cheuk F Wong, Nicholas Peters, MD, Patrik Bachtiger, Patrik Bachtiger, MBBS 2020-08-31
An FDA expanded access programm/compassionate use program for bucillamine in COVID-19 Coronavirus disease 19 infection repurposed formulation of bucillamine (gout/cystinuria/Wilson disease/influenza/COVID-19), Revive Therapeutics alone Xanthine oxidase inhibitor Revive Therapeutics Ltd Phase Not Applicable Planned 0 2020-08-28
Role of Siddha medicine in the management of Covid-19 positive patients Coronavirus disease 19 infection Variable regimens including adathodai mangapu , ammakura choornam , bramhananda bairavam , kapa sura kudineer , thalasathy vadagam Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Siddha Central Research Institute India 2020-09-03 CTRI/2020/08/027397 Phase 2 Clinical Not yet recruiting 1 20 DRSTHILLAIVANAN 2020-08-31
A phase III clinical study to assess CT-P59 in the treatment of patients with moderate-to-severe SARS-CoV-2 infection Coronavirus disease 19 infection CT-P59 alone COVID19 Spike glycoprotein inhibitor, Moesin modulator Celltrion Healthcare Co Ltd 2020-12-31 Phase 3 Clinical Planned 0 2020-08-28
Mental health of pregnant women Covid-19 pandemic Coronavirus disease 19 infection Young Adults (18-44 yrs) All India Institute of Medical Sciences India 2020-09-03 CTRI/2020/08/027396 Phase Not Applicable Not yet recruiting 1 100 Dr Vidushi Kulshrestha 2020-08-31