Last updated: Oct 06, 2020 - 02:00 BST

Title Indication Intervention Actions PatientSelection Sponsor Collaborator Country StartDate EndDate Identifiers Phase Recruitment Status Sites Trial Duration Enrollment Count Contacts LastChanged
KetoCOVID: Acute Effects of 3-hydroxybutyrate on Cardiac Function in Patients With COVID-19 Coronavirus disease 19 infection H.V.M.N Ketone Ester alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Steno Diabetes Center Odense Denmark 2020-10-01 2022-01-01 H-20021500, KetoCOVID, NCT04573764 Phase 2 Clinical Not yet recruiting 0 15 Months 12 Jens Christian Laursen, MD, Peter Rossing, MD, Tor Biering-Sørensen, MD 2020-10-05
Treatment With Anti-SARS-CoV-2 Immunoglobulin In Patients With COVID-19 Coronavirus disease 19 infection anti-SARS-CoV-2 equine immunoglobulin (F(ab')2) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Instituto D'Or de Pesquisa 2020-12-01 2021-03-31 NCT04573855, PCL04/2020 Phase 1/Phase 2 Clinical Not yet recruiting 0 4 Months 41 2020-10-05
START: A Registry Study of Serological and Virological Testing to Accelerate Recovery and Transition Coronavirus disease 19 infection PCR testing alone, blood sampling alone, standard of care assessment alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Kentucky US 2020-05-15 2023-12-31 NCT04573634, PHARM-20-COVID19-START, START Phase Not Applicable Recruiting 1 43 Months 960 Derek Forster, MD, Jill Kolesar, PharmD, MS 2020-10-05
Mesenchymal Stem Cells for the Treatment of COVID-19 Coronavirus disease 19 infection mesenchymal stem cells (PrimePro) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) US 2020-04-24 2020-09-01 NCT04573270, PRO00043080 Phase 1 Clinical Completed 0 4 Months 40 Ernst R Von Schwarz, MD, PhD 2020-10-05
AEC COVID-19: National Study 'AEC COVID-19' Coronavirus disease 19 infection Surgical procedure alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospitales Universitarios Virgen del Rocío Spain 2020-03-01 2020-09-30 AEC COVID-19, AEC-COVID, NCT04573868 Phase Not Applicable Recruiting 1 7 Months 1000 Isaias Alarcón, MD PhD, Salvador Morales, Salvador Morales-Conde, Salvador Morales-Conde, MD PhD 2020-10-05
Coping with COVID Pandemic Coronavirus disease 19 infection Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bangladesh Health Professions Institute Bangladesh 2020-10-10 CTRI/2020/10/028196 Phase Not Applicable Not yet recruiting 1 3000 Asma Islam, K M Amran Hossain, Professor Md Obaidul Haque 2020-10-05
An observational, post-registrational study to evaluate the safety and efficacy of Avifavir in the treatment of patients with COVID-19 infection Coronavirus disease 19 infection favipiravir alone RNA polymerase inhibitor ChemRar Pharma Russian Direct Investment Fund Russian Federation Phase 4 Clinical Status not specified 1 940 2020-10-05
Clinical profile of neonates with suspected or proven SARS-CoV-2 infection Coronavirus disease 19 infection, Viral pneumonia Newborn Infants (up to 5 months) Government Medical College and Hospital,Chandigarh India 2020-10-12 CTRI/2020/10/028202 Phase Not Applicable Not yet recruiting 1 30 Deepak Chawla 2020-10-05
The role of Yogic breathing techniques in progression and recovery from COVID-19 Coronavirus disease 19 infection Yoga alone, longer duration breathing technique (LDBT) alone, short duration breathing technique (SDBT) alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ministry of Ayush India 2020-10-08 CTRI/2020/10/028195 Phase Not Applicable Not yet recruiting 1 72 Dr Akshay Anand 2020-10-05
The application of ultrasound-guided superior laryngeal nerve block used for alleviation of agitation after endotracheal intubation Agitation, Coronavirus disease 19 infection, Delirium, Viral pneumonia B-guided superior laryngeal nerve block alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Shengjing Hospital of China Medical University, The First Affiliated Hospital of Wenzhou Medical University China 2020-10-01 2021-06-30 ChiCTR2000038690 Phase 2 Clinical Not yet recruiting 2 9 Months 90 Jiehao Sun 2020-10-05
A survey to assess the effectiveness of Arsenicum Album 30C as a Prophylactic medicine against COVID-19 infection Coronavirus disease 19 infection Arsenicum Album 30C alone Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Homoeopathy India 2020-10-04 CTRI/2020/10/028192 Phase Not Applicable Not yet recruiting 1 15000 Dr Raja manoharan, Dr Selvan 2020-10-05
A study to examine the impact of chronic rhinosinusitis (CRS) on COVID-19 Coronavirus disease 19 infection, Sinusitis American Academy of Allergy Asthma and Immunology China Phase Not Applicable Status not specified 1 1172 2020-10-05
Effect of fluvoxamine on cytokine in COVID-19 patients Coronavirus disease 19 infection fluvoxamine (Abidi and Sobhan Pharmaceutical companies) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shaheed Beheshti Medical University Iran 2020-07-22 IR.SBMU.NRITLD.REC.1399.177, IRCT20131115015405N4 Phase 2/Phase 3 Clinical No longer recruiting 1 40 Mitra Safa 2020-10-05
Effect of Online Psycho-educational Interventions on Psychological Health of Patients with COVID-19 Acute stress disorder, Coronavirus disease 19 infection cognitive–behavioural techniques alone, mindfulness-based stress reduction techniques alone, multimedia psychoeducational content delivery though whatsApp alone, positive psychotherapy exercise alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shiraz University of Medical Sciences Iran 2020-03-10 2020-05-14 IR.SUMS.REC.1399.011, IRCT20201001048893N1 Phase Not Applicable Completed 2 2 Months 50 Abbas Rezaeianzadeh, Maryam Shaygan, Zahra Yazdani 2020-10-05
Diabetes Outcomes in COVID-19 Pandemic Coronavirus disease 19 infection, Insulin dependent diabetes, Non-insulin dependent diabetes Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) SERVICES INSTITUTE OF MEDICAL SCIENCES Pakistan 2020-06-01 2020-07-30 16102019, NCT04573335 Phase Not Applicable Completed 1 1 Month 1282 Saira Burney, MB, FRCP (Edin) 2020-10-05
Natural History of Post-Coronavirus Disease 19 Convalescence at the National Institutes of Health Chronic fatigue syndrome, Coronavirus disease 19 infection deep phenotyping alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Neurological Disorders and Stroke National Institutes of Health Clinical Center US 2020-10-07 2024-12-31 000089-N, 10000089, NCT04573062 Phase Not Applicable Recruiting 1 50 Months 1000 Angelique Gavin, Avindra Nath, M.D. 2020-10-05
A single-site, single-arm, open, Phase I Study to Evaluate the Safety, tolerability and pharmacokinetic of CD24-Fc in healthy adults Coronavirus disease 19 infection CD24-IgFc alone Signal transducer CD24 modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Beijing Ditan Hospital Capital Medical Universty China 2020-11-05 2021-08-05 ChiCTR2000038672 Phase 1 Clinical Not yet recruiting 1 9 Months 12 Longpin Yin, xianfeng Fang 2020-10-04
Effects of pulmonary rehabilitation in patients with COVID-19 Anxiety disorder, Coronavirus disease 19 infection, Depression, Dyspnea patient health information session alone, psychosocial support alone, pulmonary training rehabilitation alone, respiratory physiotherapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Klinik Bad Reichenhall Hochschule fur Gesundheit, Bochum, Ludwig-Maximilians University of Munich Germany 2020-04-28 20-326, DRKS00023180 Phase Not Applicable Recruiting 1 100 Konrad Schultz 2020-10-04
A clinical trial to focus on patients discharged after hospitalization for moderate to severe COVID-19 disease Coronavirus disease 19 infection National Institutes of Health Phase Not Applicable Planned 0 2020-10-05
A clinical trial to investigate whether anticoagulants or antithrombotic therapy can reduce life-threatening cardiovascular or pulmonary complications in newly diagnosed COVID-19 patients who do not require hospital admission Cardiovascular disease, Coronavirus disease 19 infection, Lung disease apixaban alone, aspirin alone Factor Xa antagonist National Institutes of Health Phase Not Applicable Recruiting 0 2020-10-05
A clinical trial to investigate the safety and effectiveness heparin to prevent clotting events and improve outcomes in hospitalized COVID-19 patients Coronavirus disease 19 infection heparin alone National Institutes of Health Phase Not Applicable Recruiting 0 2020-10-05
PROVID-CAPNETZ: Clinical, molecular and functional biomarkers for Prognosis, pathomechanisms and treatment strategies of COVID-19 (PROVID) Coronavirus disease 19 infection, Lung infection, Respiratory distress syndrome, Viral pneumonia biological sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hannover Medical School Charite Universitaetsmedizin Berlin, Deutsche Forschungsgemeinschaft (DFG), German Federal Ministry of Education and Research, University of Leipzig Germany 2020-10-15 DRKS00022871, Nr. 301-2008, PROVID-CAPNETZ Phase Not Applicable Not yet recruiting 15 400 Grit Barten-Neiner 2020-10-03
Efficacy and safety of chlorpromazine in the treatment of COVID-19 patients Coronavirus disease 19 infection atazanavir + ritonavir (Razavi Pharmaceutical Institute) plus chlorpromazine (Tehran Shimi Company) Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mazandaran University of Medical Sciences Iran 2020-10-31 IR.MAZUMS.REC.1399.617, IRCT20200913048708N1 Phase 2 Clinical Not yet recruiting 1 60 Dr Majid saeedi, Ebrahim Salehifar, Roya Ghasemian 2020-10-03
UVA Light Device to Treat COVID-19 Coronavirus disease 19 infection UV light therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cedars-Sinai Medical Center Aytu BioScience Inc US 2020-09-30 2020-12-31 883, NCT04572399 Phase Not Applicable Recruiting 1 3 Months 5 Cedars-Sinai, George Chaux, MD, Melissa Hampton 2020-10-03
Low Dose Lung Radiotherapy to Treat COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia external beam irradiation (0.5 Gy) alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Lancashire Teaching Hospitals NHS Trust National Institute for Health Research (NIHR) UK 2020-10-31 2021-04-30 285167, NCT04572412 Phase 1 Clinical Not yet recruiting 1 6 Months 13 Aashish Vyas, Dennis Hadjiyiannakis, Research Access 2020-10-03
COVIDTrach: A Cohort Study of Mechanically Ventilated COVID-19 Patients Undergoing Tracheostomy Coronavirus disease 19 infection tracheostomy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University College London UK 2020-08-01 2021-08-01 COVIDTrach, NCT04572438, Z6364106/0000/00/00 Phase Not Applicable Recruiting 1 12 Months 2500 Nick JI Hamilton, MBChB PhD, Nick JI Hamilton, MBcHB PhD 2020-10-03
FloR COVID-19: Pilot, Randomized, Controlled Trial: Fluoxetine to Reduce Hospitalization From COVID-19 Infection Coronavirus disease 19 infection fluoxetine hydrochloride alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Milton S. Hershey Medical Center US 2020-09-30 2021-10-31 00015598, FloR COVID-19, NCT04570449 Phase 0 Clinical Not yet recruiting 1 13 Months 40 Erika Saunders, MD 2020-10-04
PHYTO CoV: Evaluation of phytopharmaceuticals to improve the prognosis of Covid-19 disease in Togo Coronavirus disease 19 infection Biocire alone, Immunitum alone, Immutop alone, Secure alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Togo 2020-10-15 2021-04-30 PACTR202009483194545, PHYTO CoV Phase Not Applicable Not yet recruiting 3 6 Months 250 ADJOH Seraphin, DAGNRA Claver, EKOUEVI Didier Koumavi, Ihou WATEBA Mageste, KOKOU Kouami, SALOU Mounerou 2020-10-02
Dose Ranging Trial to Assess Safety and Immunogenicity of V-590 in Healthy Adults Coronavirus disease 19 infection replication-competent VSV chimeric virus-based vaccine (COVID-19), IAVI/Batavia Biosciences/Merck & Co Inc alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) International AIDS Vaccine Initiative, Merck Sharp & Dohme Corp Merck & Co Inc 2020-10-22 2021-12-03 NCT04569786, V590-001 Phase 1 Clinical Not yet recruiting 0 13 Months 252 Medical Director 2020-10-02
COntinuation Versus Interruption of Immunomodulating Drugs in case of an Infectious disease in IMID patients (COVID I2 study), with special attention for COVID 19: a pragmatic, explorative randomized controlled trial Coronavirus disease 19 infection, Crohns disease, Inflammatory bowel disease, Psoriasis, Psoriatic arthritis, Rheumatoid arthritis, Spondylarthritis, Ulcerative colitis continued IA alone, standard of care alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sint Maartenskliniek Netherlands 2020-10-01 2022-10-01 NL73479.091.20, NL8922 Phase Not Applicable Planned 1 24 Months 2200 Merel Opdam 2020-10-02
DIEGO: A diet for the treatment of gout Coronavirus disease 19 infection, Gout usual care alone, whole food plant based diet counselling alone Reade Center for Rehabilitation and Rheumatology Netherlands 2020-09-15 2022-03-31 2020.405 - NL74142.029.20, DIEGO, NL8903 Phase not specified Recruiting 1 18 Months 30 Wendy Walrabenstein 2020-10-02
A Phase 3, Randomised, Observer-Blinded, Placebo-Controlled Trial to Evaluate the Efficacy and Safety of a SARS-CoV-2 Recombinant Spike Protein Nanoparticle Vaccine (SARS-CoV-2 rS) with Matrix-M1™ Adjuvant in Adult Participants 18-84 Years of Age in the United Kingdom Coronavirus disease 19 infection Matrix M alone, NVX-CoV2373 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Novavax Inc UK Government UK 2020-09-24 2020-004123-16 Phase 3 Clinical Recruiting 1 9000 Lakshmi Kumar 2020-10-05
BCG-PRIME: Bacillu Calmette Geurin vaccination to prevent serious respiratory tract infection and covid-19 in vulnerable elderly - and apative randomized controlled trial Coronavirus disease 19 infection, Respiratory tract infection BCG vaccine alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitair Medisch Centrum Utrecht The Netherlands Organisation for Health Research and Development Netherlands 2020-08-27 2020-003470-47, 74730.041.20, BCG-PRIME, CoV-2_DDI Phase 4 Clinical Not yet recruiting 1 5200 2020-10-02
A Pilot study platform to investigate the pharmacodynamics on QT‐prolongation and pharmacokinetics after multiple dose administration of potential combination treatments for COVID-19 in healthy volunteers Coronavirus disease 19 infection lopinavir + ritonavir plus ribavirin HIV protease inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Medical University of Vienna Austria 2020-09-14 2020-002314-40, CoV-2_DDI Phase 2 Clinical Not yet recruiting 1 16 2020-10-05
A randomized, double-blind, placebo-controlled, adaptive-design study to assess the safety and efficacy of daily 200 mg fluvoxamine as add-on therapy to standard of care in moderate severity COVID-19 patients Coronavirus disease 19 infection fluvoxamine alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Sigmadrugs Kft Hungary 2020-09-17 2020-002299-11, SD-COVID19-01 Phase 2 Clinical Not yet recruiting 1 100 2020-10-02
Study on Traditional Chinese Medicine Intervention Program for the Sequela of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Jiexingjunzi granule alone, Qibei Fuzheng granule alone Beijing University of Chinese Medicine Beijing institute of Traditional Chinese Medicine China 2020-08-01 2021-08-01 ChiCTR2000038740 Phase 0 Clinical Not yet recruiting 1 12 Months 200 Chengxiang Wang, Shan Zhang 2020-10-02
Analysis on the Distribution of TCM Syndromes in convalescent novel coronavirus pneumonia (COVID-19) patients Coronavirus disease 19 infection, Viral pneumonia Beijing University of Chinese Medicine Beijing institute of Traditional Chinese Medicine China 2020-08-01 ChiCTR2000038739, ChiMCTR2000003991 Phase 0 Clinical Not yet recruiting 1 800 Chengxiang Wang, Shan Zhang 2020-10-02
Angiotensin (1-7) for the Treatment of COVID-19 in Hospitalized Patients Coronavirus disease 19 infection angiotensin (1-7) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Stanford University US 2020-11-30 2021-05-31 58189, NCT04570501 Phase 1/Phase 2 Clinical Not yet recruiting 1 6 Months 160 Kevin V Grimes, MD 2020-10-02
An observational, single-center study to determine if early treatment of patients with COVID-19 pneumonia with tocilizumab and/or steroids was associated with better outcome Coronavirus disease 19 infection, Pneumonia methylprednisolone alone, tocilizumab alone, methylprednisolone plus tocilizumab Universita Degli Studi di Genova Phase Not Applicable Status not specified 0 196 2020-10-04
An experimental study to find out the impact of post COVID physiotherapy and rehabilitation in Bangladesh Coronavirus disease 19 infection physiotherapy alone, rehabilitation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Bangladesh 2020-10-07 CTRI/2020/10/028179 Phase Not Applicable Not yet recruiting 1 300 KM Amran Hossain, Mohammad Anwar Hossain 2020-10-05
A cross sectional study to identify the symptoms that are presenting by COVID-19 suffering people in Bangladesh Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bangladesh 2020-10-05 CTRI/2020/09/028165 Phase Not Applicable Not yet recruiting 1 1000 KM Amran Hossain, Mohammad Anwar Hossain 2020-10-02
Pediatric COVID-19 Antibody Study Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) Yokohama City University Japan Agency for Medical Research and Development Japan 2020-10-12 UMIN000041769 Phase Not Applicable Not yet recruiting 1 50 Kenichi Nishimura, Takeharu Yamanaka 2020-10-04
A clinical trial to know the efficacy of Homoeopathic medicine as an adjuvant therapy to Standard treatment in COVID-19 patients Coronavirus disease 19 infection homoeopathic intervention alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Homoeopathy India 2021-10-04 CTRI/2020/09/028164 Phase Not Applicable Not yet recruiting 1 50 Dr Nithiyaselvi, Dr Raja manoharan 2020-10-04
A prospective cohort study of the effects of COVID-19 in pregnancy and the neonatal period Coronavirus disease 19 infection Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Government Medical College, Nagpur Nigeria, Russian Federation, Pakistan, Japan, Ghana, France, India, US, Italy, Indonesia, Egypt, Mexico, Spain, Macedonia, The Former Yugoslav Republic of, Brazil, UK, Argentina 2020-10-01 CTRI/2020/09/028162 Phase Not Applicable Not yet recruiting 17 1500 Dr Manjushri Waikar 2020-10-03
CPT-R-Nepal: Clinical Protocol for Convalescent Plasma and Remdesivir Therapy in Nepal Coronavirus disease 19 infection standard of care alone, convalescent plasma plus remdesivir COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Nepal Health Research Council Ministry of Health and Population, Nepal Nepal 2020-07-30 2020-12-30 CPT-R-Nepal, NCT04570982, NHRC2020-001 Phase Not Applicable Recruiting 6 5 Months 200 Anup Bastola, MD., Dr. Pradip Gyanwali,MD, Janak Koirala, MD, MPH, Krishna Pokhrel, MD., Meghnath Dhimal, PhD, Pradip Gyanwali, MD, Rajan Pandey, MD., Santa K Das, MD., Saroj Bhattarai, MSc., Sher B Kamar, MD., Uday N Singh, MD. 2020-10-03
Oral VIRANORM (Ayurvedic Proprietary Medicine) Compared to Placebo in Subjects with Asymptomatic or Mild COVID-19 Coronavirus disease 19 infection Standard of Care (SOC) alone, VIRANORM alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) India 2020-10-05 CTRI/2020/09/028158 Phase Not Applicable Not yet recruiting 3 250 Dr Padmanaban KG, Dr S Poorna Prasad, Dr Sridhar MK, Dr V Channaraya 2020-10-03
GI-COVID: GM-CSF Inhalation to Prevent ARDS in COVID-19 Pneumonia Coronavirus disease 19 infection, Hypoxia, Respiratory distress syndrome, Viral pneumonia molgramostim alone, rapid nebulizer system alone CSF-1 agonist, GM-CSF receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Giessen Germany 2020-09-24 2022-12-25 2020-001654-21, GI-COVID, KKS-279, NCT04569877 Phase 2 Clinical Recruiting 1 27 Months 238 Nelli Ens-Jäger, Susanne Herold, Prof., Susanne Herold, Prof. Dr. 2020-10-03
Perspective of MBBS Students towards Teaching through Onscreen Classes Coronavirus disease 19 infection Onscreen classes alone Adolescents (13-17 yrs), Young Adults (18-44 yrs) Punjab Institute Of Medical Sciences India 2020-10-10 CTRI/2020/09/028157 Phase Not Applicable Not yet recruiting 1 500 Dr Baljit Jassal, Dr Nipunjot Grewal, Rakesh Kumar 2020-10-01
Multicenter Study of the Integrative and Complementary Practice of the Use of Ozone Gas in Outpatients with COVID-19 Coronavirus disease 19 infection conventional treatment alone, ozone therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Brazil 2020-09-25 30883120.8.1001.0008, 4,100,138, RBR-97nt6j, U1111-1257-7973 Phase 1/Phase 2 Clinical Not yet recruiting 1 142 Arnoldo de Souza 2020-10-03
Comparative Study of Artificial Intelligence and Radiologists in Assessing Severity of COVID19 Patient Images Coronavirus disease 19 infection LungIQ alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) India 2020-10-04 CTRI/2020/09/028156 Phase Not Applicable Not yet recruiting 1 500 Dr Amit Kumar Sahu 2020-10-03
A survey is to study the prophylactic effect of homoeopathic medicine namely Arsenicum album 30 against COVID 19 infection in Madurai Tamilnadu Coronavirus disease 19 infection Arsenicum Album 30C alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Homoeopathy India 2020-10-05 CTRI/2020/09/028153 Phase Not Applicable Not yet recruiting 1 10000 Dr Austin Jose, Dr karthikeyan 2020-10-03
Oral VIRAHALT (Novel Immunomodulatory Herbal combination) Compared to standard of care in Subjects with Moderate to Severe COVID-19 Coronavirus disease 19 infection Standard of Care alone, VIRAHALT (Immunomodulatory Herbal combination) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) India 2020-10-05 CTRI/2020/09/028133 Phase Not Applicable Recruiting 2 60 Dr Padmanaban KG, Dr S Poorna Prasad, Dr V Channaraya 2020-10-03
Research on the maintenance and improvement of physical and mental functions of elderly people under the self-restraint caused by COVID-19 by using a remote system to connect their homes Coronavirus disease 19 infection, Muscle weakness, Psychiatric disorder information and communication technology alone, online gymnastics and exercise instructions alone, online interactive communication alone, salon-gymnastics physical therapy alone, tele-rehabilitation alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) Japan 2020-07-01 UMIN000041458 Phase Not Applicable Not yet recruiting 1 40 Kazunori Kojima 2020-10-05
NHS CHECK: The psychosocial impact of the COVID-19 pandemic on NHS affiliated staff - monitoring the response to the pandemic and the evaluation of local and national staff support programs Coronavirus disease 19 infection, Psychiatric disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) King's College London Medical Research Council, NIHR Maudsley Biomedical Research Centre, Rosetrees Trust, University College London UK 2020-04-01 2022-04-23 IRAS 282686, CPMS 46176, ISRCTN18395399, NHS CHECK Phase Not Applicable Recruiting 18 24 Months 20000 Miss Rupa Bhundia, Prof Simon Wessely 2020-10-01
Auscul-X: Evaluating Auscul-X, a Touch Free Digital Stethoscope Coronavirus disease 19 infection Auscul-X System alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ottawa Heart Institute Research Corp Canada 2020-09-30 2021-01-31 AUSCUL-X, Auscul-X, NCT04570189 Phase Not Applicable Not yet recruiting 1 4 Months 40 Aun Yeong Chong, BSc(Med),MD, Benjamin Chow, MD, Benjamin Chow, MD,FRCPC, Farrah Ahmed, BSc., John Phillips, BSc., Melissa Spero, CRN, CCRP 2020-10-01
Intravenous L-Citrulline to Delay and Potentially Prevent the Need for Invasive Mechanical Ventilation for Acute Hypoxemic Respiratory Failure in Patients With COVID-19 (SARS-CoV-2) Illness Coronavirus disease 19 infection, Hypoxia, Respiratory failure L-citrulline alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Asklepion Pharmaceuticals LLC US 2020-09-28 2021-12-28 CIT-COVID19-002-01, NCT04570384 Phase 2 Clinical Not yet recruiting 1 15 Months 60 Gurdyal Kalsi, MD, MFPM, Michael P Wilson, MD, Nikhil K Meena, MD, Study Site Contact, Vincent Elliott 2020-10-01
Effect of Nasal Steroid in the Treatment of Anosmia Due to COVID-19 Disease Ageusia, Coronavirus disease 19 infection, Dysomia Ophtamesone alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Iraq 2020-08-01 2020-10-15 1148, NCT04569825 Phase 0 Clinical Recruiting 1 2 Months 250 Raid M Al-Ani, FIBMS (ENT) 2020-10-01
Ravulizumab and COVID-19 Coronavirus disease 19 infection, Thrombotic microangiopathy ravulizumab alone, standard care alone Complement C5 factor inhibitor, IgG receptor FcRn large subunit p51 modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Brigham & Women's Hospital US 2020-11-30 2021-11-30 092420, NCT04570397 Phase 3 Clinical Not yet recruiting 1 12 Months 32 Aliza Anwar Memon, M.B.B.S, Andrew M Siedlecki, M.D 2020-10-05
A cross sectional study to assess the impact of COVID-19 on patints with non communicable disease at AYUSH LSD clinics Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Council for Research in Homoeopathy India 2020-10-05 CTRI/2020/09/028132 Phase Not Applicable Not yet recruiting 2 450 Dr Debadatta Nayak, Dr Praveen Oberai, Dr Varanasi Roja 2020-10-01
BigCoviData: Clinical Characteristics and Prognostic Factors of Patients With COVID-19 (Coronavirus Disease 2019) Coronavirus disease 19 infection, Viral pneumonia Big Data system alone Castilla-La Mancha Health Service Spain 2020-01-01 2021-10-30 BIGCOVIDATA, BigCoviData, NCT04569851 Phase Not Applicable Recruiting 2 21 Months 100000 Joan B Soriano, MD, PhD, José Luis Izquierdo, MD, PhD, Julio Ancochea, MD, PhD 2020-10-05
A study of Cordyceps Capsules as an Add-On Therapy in patients with moderate COVID 19 Infection Coronavirus disease 19 infection Cordyceps Capsules alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) India 2020-10-02 CTRI/2020/09/028131, Cordyceps-2001 Phase Not Applicable Not yet recruiting 1 60 Dr Sagar Sinha, Prof Dr Siddharth P Dubhashi 2020-10-05
Homoeopathy in the prevention of COVID-19 Coronavirus disease 19 infection Arsenicum album 30 alone, Influenzinum 30 alone, Oscillococcinum alone Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Mahesh Bhattacharyya Homoeopathic Medical College, Ministry of Ayush India 2020-10-06 CTRI/2020/09/028122 Phase 3 Clinical Not yet recruiting 1 15992 Malay Mundle, Shubhamoy Ghosh 2020-10-05
ANTIOX-COVID: Antioxidants as Adjuvant Therapy to Standard Therapy in Patients With COVID-19 Coronavirus disease 19 infection, Septic shock, Viral pneumonia Variable regimens including N-acetyl cysteine , melatonin , pentoxifylline , vitamin C , vitamin E Phosphoric diester hydrolase inhibitor Instituto Nacional de Cardiologia Ignacio Chavez, Instituto Nacional de Ciencias Medicas y Nutricion Mexico 2020-08-19 2020-11-15 09-CEI-011-20160627, ANTIOX-COVID, NCT04570254 Phase 2 Clinical No longer recruiting 1 2 Months 11 Adrián Palacios Chavarria, MD, José Guillermo Domínguez Cherit, MD, Maria Elena Soto Lopez, PhD 2020-10-03
A study to evaluate the response to and recovery from total knee arthroplasty (TKA) in patients with antibodies to COVID-19 Coronavirus disease 19 infection, Knee injury total knee arthroplasty (TKA) alone Hospital for Special Surgery NY US Phase Not Applicable Status not specified 1 Meghan A. Kirksey, Miguel Otero, Peter K. Sculco 2020-10-01
A clinical study to evaluate the mechanisms of cytokine storm in patients with COVID-19 Coronavirus disease 19 infection anakinra alone Type I IL-1 receptor antagonist Hospital for Special Surgery NY US Phase Not Applicable Status not specified 1 Lionel B. Ivashkiv, Mary K. Crow, Mikhail Olferiev 2020-10-01
STORM-HCW: Screening of Health-care Workers in an University Hospital Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Milano-Bicocca Italy 2020-06-01 2020-12-01 NCT04567836, STORM-HCW, STORM-HCW Phase Not Applicable Recruiting 1 6 Months 3000 Paolo Bonfanti 2020-10-05
A phase III clinical trial to test efficacy and safety of CoronaVac in Turkey Coronavirus disease 19 infection CoronaVac alone Sinovac Biotech Ltd Turkey Phase 3 Clinical Status not specified 1 2020-09-30
HOW-R-U? CTP: Feasibility and acceptability of a volunteer-peer telephone support programme - A COVID-19 response Coronavirus disease 19 infection, Depression supportive telephone calls alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Northern Hospital, Australia Australia 2020-10-05 ACTRN12620000975998, HOW-R-U? CTP Phase Not Applicable Not yet recruiting 1 100 Dr Marissa Dickins, Prof Judy Lowthian 2020-10-02
National Asthma Treatment Survey in Australian adults Coronavirus disease 19 infection web-based survey alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Oceanic Ancestry National Health and Medical Research Council, Woolcock Institute of Medical Research Australia, New Zealand 2020-11-01 ACTRN12620000977976p, U1111-1257-3764 Phase Not Applicable Not yet recruiting 2 8000 Dr Sharon Davis, Prof Helen Reddel 2020-10-05
TPEP-Corona-1: A randomized, double-blind, placebo-controlled trial of oral ivermectin for outpatient treatment of those at high risk for hospitalization due to COVID-19 Coronavirus disease 19 infection, Viral pneumonia ivermectin alone Chloride channel modulator Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Neuroscience Trials Australia Leona M and Harry B Helmsley Charitable Trust Australia 2020-10-05 ACTRN12620000982910p, TPEP-Corona-1 Phase 3 Clinical Not yet recruiting 1 400 Dr Mark Stein, Ms Michele Sallaberger 2020-10-01
Micronized and Ultramicronized Palmitoylethanolamide in COVID-19 Patients Coronavirus disease 19 infection, Inflammatory disease, Neuritis, Viral pneumonia Normast MPS (Epitech Group Srl) alone, standard therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Epitech Group Srl Azienda Ospedaliera Sant' Andrea Italy 2020-10-31 2021-11-30 NCT04568876, NORM_MPS-COVID, NORM_MPS_11 Phase 4 Clinical Not yet recruiting 1 13 Months 40 Epitech Group SpA Clinical Research, Prof.ssa Flaminia Coluzzi, MD 2020-10-03
The Phase I Clinical Trial of Booster Vaccination of Adenovirus Type-5 Vectored COVID-19 Vaccine Coronavirus disease 19 infection Ad5-nCoV alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Jiangsu Province Centers for Disease Control and Prevention China 2020-09-26 2021-09-27 JSVCT100, NCT04568811 Phase 1 Clinical No longer recruiting 1 12 Months 89 2020-10-05
Study of AZD-1222 for the Prevention of COVID-19 in Japan Coronavirus disease 19 infection AZD-1222 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) AstraZeneca plc IQVIA RDS Pty Ltd Japan 2020-08-23 2021-09-06 D8111C00002, NCT04568031 Phase 1/Phase 2 Clinical Recruiting 5 12 Months 12 AstraZeneca Clinical Study Information Center 2020-10-01
SAR-COVID: Argentinian Registry of Patients With Rheumatic Diseases and COVID-19 Infection Coronavirus disease 19 infection, Joint disease Immunosuppressive drug treatment alone, immunomodulatory drug treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Argentina 2020-08-18 2021-12-31 01, NCT04568421, SAR-COVID Phase Not Applicable Recruiting 1 16 Months 3000 Carolina Isnardi, MD, Guillermo Pons-Estel, Guillermo Pons-Estel, PhD, Guillermo Posn-Estel, PhD 2020-10-05
Prevention of COVID-19 Infection to Severe Pneumonia or ARDS Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia mosedipimod alone CCL26 gene inhibitor, TLR modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Enzychem Lifesciences Corp US 2020-10-06 2021-11-30 EC-18-204, NCT04569227 Phase 2 Clinical Not yet recruiting 1 13 Months 60 Dr. Cameron Robert Wolfe, Ji Sun Park, Ph.D., John Choi, M.S. 2020-10-01
Minnesota COVID-19 Testing Project Coronavirus disease 19 infection emphasis of government involvement alone, messaging alone, survey incentive alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Harvard University Abdul Latif Jameel Poverty Action Lab US 2020-09-28 2021-06-30 IRB20-1444, NCT0456888 Phase Not Applicable Not yet recruiting 1 9 Months 1000 Marcella Alsan, MD, MPH, Ph, Min Jeong (Joyce) Kim, B 2020-10-01
RECOVER: Effectiveness of an Exercise Re-training Program on Dyspnea in Patients After Acute Respiratory Distress Syndrome Secondary to Severe COVID-19 Pneumonia in Post-ICU Coronavirus disease 19 infection, Dyspnea, Respiratory distress syndrome, Viral pneumonia specific exercise rehabilitation treatment alone, strengthening exercise alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Groupe Hospitalier Paris Saint-Joseph Assistance Publique Hopitaux de Paris, Central Hospital, Versailles, Centre Hospitalier Victor Dupouy, Saint Anne's Hospital France 2020-08-07 2022-05-07 NCT04569266, RECOVER, RECOVER Phase Not Applicable Recruiting 1 21 Months 200 DRC, Helene BEAUSSIER, PharmD, P, PHILIPPART François, MD, ROMANET Christoph, ROMANET Christophe 2020-10-01
BIO-COCO-NEUROSCIENCES: Evaluation of Biological Response to SARS-COV2 (COVID-19) in Patients With Pre-existing Neurological Disease or Newly Neurological Symptoms Coronavirus disease 19 infection, Neurological disease, Psychiatric disorder PCR alone, chest scanner alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris Institut du Cerveau et de la Moelle epiniere France 2020-10-15 2022-10-15 APHP200845, BIO-COCO-NEUROSCIENCES, NCT04568707 Phase Not Applicable Not yet recruiting 1 24 Months 200 Céline LOUAPRE, MD, Jean-Christophe CORVOL, MD,PHD 2020-10-01
A Clinical Evaluation of COVID-19 Rapid Point of Care Antigen Tests Coronavirus disease 19 infection, Respiratory tract infection SARS-CoV-2 direct antigen rapid test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) E25Bio Inc Sarah Cannon Research Institute US 2020-04-24 2020-09-24 E25001_NEU2012, NCT04568356 Phase Not Applicable Completed 3 5 Months 200 Gina Remington, RN MSN, Klepler N De Almeida, MD, Patrice Feaster, RN 2020-09-30
COICA: COVID-19 Infection in Cancer Pantients Coronavirus disease 19 infection, Urinary tract tumor Italy 2020-01-01 2021-08-31 COICA, COICA_PAG_01, NCT04569292 Phase Not Applicable Recruiting 1 20 Months 150 Data Manager Oncology Unit, Giuseppe Di Lorenzo 2020-10-02
Telerehabilitation of Reduced Physiotherapy Service in Covid-19 Pandemic Process in Lung Surgery Patients Coronavirus disease 19 infection, Lung tumor Telerehabilitation alone, exercise program alone, progressive mobilization program alone, teleconference exercise alone, thoracotomy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Istanbul Medipol University Hospital Turkey 2020-09-25 2021-05-01 NCT04568564, PostopTele Phase Not Applicable Recruiting 1 7 Months 40 Esra pehliva 2020-10-01
COVID-19 Tests With Saliva Specimens Coronavirus disease 19 infection Orasure collection kit alone, SDNA1000 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) US 2020-07-28 2021-06-27 NCT04567953, PLRD202001 Phase Not Applicable No longer recruiting 1 11 Months 2000 Wenli Zhou, PhD 2020-10-01
Combination of Chemopreventive Agents (All- Trans Retinoic Acid and Tamoxifen) as Potential Treatment for the Lung Complication of COVID-19 Coronavirus disease 19 infection, Lung disease, Respiratory failure, Respiratory tract infection standard treatment alone, all trans retinoic acid plus tamoxifen Estrogen receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kafrelsheikh University Egypt 2020-09-30 2020-11-30 COVID-2019, NCT04568096 Phase 2 Clinical Not yet recruiting 2 2 Months 160 Mahmoud Elkazzaz, B.Sc,M.Sc in Biochemistry 2020-10-05
A retrospective study to evaluate the efficacy and safety of anakinra in patients with COVID-19 associated pneumonia and acute severe respiratory failure Coronavirus disease 19 infection, Inflammatory disease, Respiratory distress syndrome, Viral pneumonia anakinra alone, standard-of-care treatment alone Type I IL-1 receptor antagonist Aix-Marseille Université France Phase Not Applicable Status not specified 1 22 2020-09-30
RESCUE: Convalescent Plasma in COVID-19 Elderly Patients Coronavirus disease 19 infection, Respiratory failure convalescent plasma alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) Azienda Socio Sanitaria Territoriale di Mantova Italy 2020-05-15 2020-09-03 ASSTMANTOVA, NCT04569188, RESCUE Phase 2 Clinical Completed 1 3 Months 21 Massimo Franchini 2020-10-05
ImmunoCOVID: Evaluation of Humoral Immunity Following COVID-19 in Pregnancy Coronavirus disease 19 infection, Influenza virus infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Imperial College London UK 2020-09-16 2023-07-03 20SM6089, ImmunoCOVID, NCT04568044 Phase Not Applicable Recruiting 2 33 Months 96 Charlotte-Eve Short, PhD, Head of Research Governance and Integrity, Nishel M Shah, PhD, Research Delivery Operations Manager, Senior Research Facilitator 2020-10-01
A case-control study to compare RLF-100 with standard of care in the treatment of patients with critical COVID-19 and respiratory failure Coronavirus disease 19 infection, Respiratory failure aviptadil (inhaled, sarcoidosis/acute lung injury/acute respiratory distress syndrome associated COVID-19), Relief Therapeutics Holding alone Adrenergic receptor antagonist, VIP receptor agonist NeuroRx Inc Phase Not Applicable Status not specified 0 51 2020-10-05
Safety, Tolerability, and Pharmacokinetics of Anti-Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Chicken Egg Antibody (IgY) (COVID-19) Coronavirus disease 19 infection anti-SARS-CoV-2 IgY alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Stanford University Australia 2020-09-18 2020-12-31 CVR001, NCT04567810 Phase 1 Clinical Recruiting 1 3 Months 48 Daria Mochly-Rosen, PhD, Michaela Lucas, MD, Study Team 2020-10-05
Passive Microwave Radiometry (MWR) and AI for COVID-19 Complications Early Diagnostics of Lungs Coronavirus disease 19 infection, Viral pneumonia MWR2020 alone, passive microwave radiometry alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) International Medical University, University of Edinburgh Kyrgyzstan 2020-07-01 2020-08-01 01-2/141 27, NCT04568525 Phase Not Applicable Completed 1 1 Month 195 Batyr Osmonov 2020-10-01
The Noninvasive Ventilation to COVID-19 Patients Coronavirus disease 19 infection, Respiratory failure noninvasive ventilation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The First Affiliated Hospital of Guangzhou Medical College China 2020-02-01 2020-07-01 FAHGUANGZHOUYLS03, NCT04568655 Phase Not Applicable Completed 1 5 Months 23 Zhang Jianheng 2020-10-02
Waxing and Waning of Serum SARS CoV-2-IgG Level in COVID-19 Exposed Population Coronavirus disease 19 infection Pakistan 2020-07-01 2020-11-30 LGH007, NCT04568850 Phase Not Applicable No longer recruiting 1 5 Months 50 Amina Asif, MPhilMicro 2020-10-01
Prevalence and Risk Factors for Venous Thromboembolic Events in Critically Ill Patients With COVID-19 Coronavirus disease 19 infection, Deep vein thrombosis, Respiratory failure color doppler alone, ultrasonography alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Switzerland 2020-03-03 2020-05-28 2020-01266, NCT04567927 Phase Not Applicable Completed 1 2 Months 80 Chiesa Alessandro Felice 2020-10-01
A Survey Study to Assess the Impact of the COVID-19 Pandemic on Participants With Pre-Existing Mental Health Diagnosis Coronavirus disease 19 infection, Psychiatric disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Siyan Clinical Corp US 2020-09-18 2021-12-31 NCT04568135, SCR-SUR-001 Phase Not Applicable Not yet recruiting 2 15 Months 1000 Tiffany Morgan 2020-10-01
Effect of Inhaled Nitric Oxide for the treatment of COVID-19 Coronavirus disease 19 infection nitric oxide alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Council for Scientific and Technological Development Brazil 2020-10-10 34578820.6.1001.5336, 4,282,107, RBR-8nfx26, U1111-1254-0466 Phase 2 Clinical Not yet recruiting 1 110 Marcus Herbert Jones, Marcus Jones 2020-10-05
Presenting Nutrition Characteristics, Comorbidities and Outcomes of COVID-19 in African Humanitarian Settings Coronavirus disease 19 infection Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Johns Hopkins Bloomberg School of Public Health Centers for Disease Control and Prevention Sudan, Congo, The Democratic Republic of the 2020-10-31 2021-03-31 13736, NCT04568499 Phase Not Applicable Not yet recruiting 2 5 Months 1000 Shannon Doocy, PhD 2020-10-01
Prospective Determination of COVID-19 Infection Rate in a Chemotherapy Unit in Mexico Coronavirus disease 19 infection polymerase chain reaction alone Instituto Nacional de Ciencias Medicas y Nutricion National Institute Of Genomic Medicine Mexico Mexico 2020-06-11 2020-10-30 HEM-3412-20-20-1, NCT04567979 Phase Not Applicable No longer recruiting 1 4 Months 149 David Huitzil m, Fidel D Huitzil Meléndez, MD 2020-10-01
COVID-19 Biorepository Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Kansas Medical Center US 2020-04-15 2021-12-31 NCT04568148, STUDY#00145602 Phase Not Applicable Recruiting 1 20 Months 50 Christine M Cook, MD, Leslie A Spikes, MD, Luigi R Boccardi, BS 2020-10-02
Surfactant-BL in Adult Acute Respiratory Distress Syndrome Due to COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure High-flow oxygen therapy alone, Standard treatment alone, non-invasive ventilation alone, surfactant-BL, Biosurf LLC alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Russian Federation 2020-07-03 2021-12-31 NCT04568018, SUR/ARDS-2020 Phase Not Applicable Recruiting 1 17 Months 120 Anastasia Evdokimova, Sergey Avdeev, D.M.S. 2020-10-01
Safety, Tolerability and Immunogenicity of the Candidate Vaccine MVA-SARS-2-S Against COVID-19 Coronavirus disease 19 infection MVA-SARS-2-S alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Universitätsklinikum Hamburg-Eppendorf Deutsches Zentrum für Infektionsforschung, Ludwig-Maximilians University of Munich, Philipps University Marburg Medical Center Germany 2020-10-31 2021-05-31 NCT04569383, UKE-DZIF-SARS-COV-2 Phase 1 Clinical Not yet recruiting 1 7 Months 30 Marylyn M Addo, MD 2020-10-01
Evaluation of Lymphedema Patients Status During COVID-19 Pandemic Anxiety disorder, Coronavirus disease 19 infection, Depression, Lymphedema, Phobia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fatih Sultan Mehmet Training and Research Hospital Turkey 2020-06-01 2020-08-01 FEYZAAKANBEGOGLU, NCT04568005 Phase Not Applicable Completed 1 2 Months 60 Feyza Akan Begoğlu, MD 2020-10-01
CAASP: COVID-19-associated Anxiety of Pregnant Women for Anomalies, Stillbirth and Preterm Labor Anxiety disorder, Coronavirus disease 19 infection Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Martin-Luther-Universitaet Germany 2020-10-01 2021-07-31 CAASP, NCT04568551, UKGEB001 Phase Not Applicable Recruiting 1 10 Months 300 Marcus Riemer, Marcus Riemer, MD 2020-10-05
Rapid Turnaround, Home-based Saliva Testing for COVID-19 Coronavirus disease 19 infection HandyFuge-LAMP alone, Saliva test alone, loop-mediated isothermal amplification (LAMP) assay alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Stanford University US 2020-09-30 2021-03-31 58629, NCT04568122 Phase Not Applicable Not yet recruiting 1 6 Months 3015 Euan A Ashley, MRCP, DPhil, Manisha Desai, PhD, Manu Prakash, PhD 2020-10-01
COVID-19 and Venous Thromboembolism Risk Coronavirus disease 19 infection, Thromboembolism Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of California San Francisco Kaiser Permanente US 2020-01-01 2022-06-21 NCT04569344, NOACS-1510-32651_ENHANCEMENT Phase Not Applicable Recruiting 2 29 Months 40000 Alan S. Go, MD, Kristi Reynolds, PhD, MPH, Margaret C Fang, MD 2020-10-03
A phase II clinical trial of tolimidone in the treatment of patients who were recently diagnosed with COVID-19, have early symptoms, but were not hospitalized Coronavirus disease 19 infection tolimidone alone Insulin sensitizer, Lyn tyrosine kinase stimulator Melior Pharmaceuticals Inc University of Pittsburgh Medical Center Phase 2 Clinical Planned 0 428 2020-09-30
Effect of poor sleep hygiene and screen time usage on sleep Acute stress disorder, Coronavirus disease 19 infection Young Adults (18-44 yrs) Sri Ramachandra Institute of Higher Education and Research India 2020-10-01 CTRI/2020/09/028083 Phase Not Applicable Not yet recruiting 1 330 Dr Priscilla Johnson, V Sudha Kumari 2020-10-01
ARIAA-2: Adaptability and Resilience in Aging Adults-2 Coronavirus disease 19 infection, Lower back pain Resilience Intervention alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Florida National Institute on Aging US 2020-01-21 2021-05-01 4R00AG052642-03, 5K99AG052642-02, ARIAA-2, IRB201802729, NCT04068922 Phase Not Applicable Recruiting 1 15 Months 60 Emily Bartley, PhD, Emily J Bartley, Ph.D 2020-09-30
REPERCOV: Identifying Functional and Psycho-social Complaints After Hospitalization for SARS-CoV-2 Infection (COVID 19) Coronavirus disease 19 infection, Psychiatric disorder questionnaire alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier le Mans France 2020-06-11 2022-06-11 CHM-2020/S10/04, NCT04561154, REPERCOV Phase Not Applicable Recruiting 1 24 Months 134 Christelle JADEAU, Hikombo HITOTO 2020-09-30
A phase I, multicenter, randomized, controlled trial to evaluate the safety and efficacy of inhaled Ampion in combination with standard of care for the treatment of COVID-19 infected patients hospitalized for respiratory distress Coronavirus disease 19 infection, Respiratory distress syndrome Ampion (intranasal, inflammation), Ampio/DMI Biosciences alone, standard of care alone Stem cell antigen-1 inhibitor Ampio Pharmaceuticals Inc Phase 1 Clinical Not yet recruiting 0 40 2020-09-30
Variation in biochemical parameters in COVID-19 infection Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Sri Ramachandra Institute of Higher Education and Research India 2020-10-01 CTRI/2020/09/028069 Phase Not Applicable Not yet recruiting 1 150 Dr K Sowmya 2020-10-01
The Causal Effects of Old Age Pensions Coronavirus disease 19 infection Assistance with old age pension application alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Bureau of Economic Research Inc India 2019-02-04 2027-12-31 223749, NCT04029194 Phase Not Applicable No longer recruiting 1 106 Months 1459 Esther Duflo 2020-09-30
Self-help Guided by Lay Providers for Anxiety in Older Adults Coronavirus disease 19 infection, Generalized anxiety disorder Self-help guided by a lay provider alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universite Laval Canadian Institutes of Health Research, Convenance institutionnelle CIUSSS de la Capitale-Nationale, Universite de Sherbrooke Canada 2019-03-11 2023-03-31 NCT03768544, SIRUL 118715 Phase Not Applicable Recruiting 3 48 Months 130 Catherine Filion, M.A., Félix-Antoine Desruisseaux, B.A., Patrick Gosselin, Ph.D., Philippe Landreville, Ph.D., René-Marc Lavigne, Ph.D., Sébastien Grenier, Ph.D. 2020-10-05
Vaginal Cleansing Before Cesarean Delivery to Reduce Infection Coronavirus disease 19 infection, Vaginal infection Abdominal Cleansing alone, Vaginal Cleansing alone, betadine alone, chlorhexidine alone, povidone-iodine alone Healthy volunteers accepted, Female Washington University in St Louis US 2015-08-31 2021-03-31 201505127, NCT02495753 Phase 2 Clinical Recruiting 1 67 Months 608 Alison G Cahill, MD, Antonina I Frolova, MD, Lorene A Temming, MD 2020-10-01
An observational, retrospective study to evaluate the outcomes of tocilizumab in patients with severe coronavirus disease 2019 Coronavirus disease 19 infection antiviral agents alone, tocilizumab alone Hamad Medical Corp Phase Not Applicable Status not specified 0 25 2020-09-30
Effectiveness of an equipment to reduce the dispersion of particles in emergency dental care during the Covid-19 pandemic Coronavirus disease 19 infection, Tooth disease protective equipment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Pontifícia Universidade Católica - PUCPR Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul Brazil 2020-09-01 30717820.1.0000.5336, 4.021.042, RBR-9rnkbs, U1111-1258-5375 Phase Not Applicable Recruiting 1 Maximiliano Schunke Gomes 2020-09-30
Supporting the Health and Well-being of Children With Intellectual and Developmental Disability During COVID-19 Pandemic Coronavirus disease 19 infection, Intellectual impairment Best Message + Augmented Message or Implementation Strategy alone, Best Message Alone alone, Focused/Targeted Message alone, General Communication Message alone Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Washington University School of Medicine, US Hugo W. Moser Research Institute at Kennedy Krieger, Inc, National Institutes of Health, University of Missouri US 2020-11-01 2022-09-21 202009060, NCT04565509 Phase Not Applicable Not yet recruiting 2 22 Months 2500 Bradley Schlaggar, MD, PhD, George S Grotto, PhD, Jason G. Newland, MD 2020-10-01
Testing Multiple Behavioral Science Strategies to Increase Flu-Shot Rates Coronavirus disease 19 infection, Influenza virus infection Flu shot text messages alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Pennsylvania State University Geisinger Clinic 2020-09-30 2021-03-31 843523, NCT04565353 Phase Not Applicable Not yet recruiting 0 6 Months 125600 Dena Gromet, PhD, Joseph Kay, PhD 2020-10-01
DPPFit: Developing and Testing a Technology-Based Translation of the DPP to Address Prediabetes in a Primary Care Setting Coronavirus disease 19 infection, Non-insulin dependent diabetes Diabetes Prevention Program alone, Fitbit alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Augusta University US 2020-01-01 2021-02-15 DPPFit, IRB#1193356, NCT04564586 Phase Not Applicable No longer recruiting 1 13 Months 32 Jessica L Stewart, MPH 2020-10-01
Pilot Study to Evaluate Effect of CHX0.12/CPC 0.05 of SARS-CoV-2 Viral Load in COVID-19 Patients Coronavirus disease 19 infection CHX0.12+CPC0.05 oral rinsing alone, Chlorhexidine + Cetyl Pyridinium Chloride alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dentaid, S.L. Colombia 2020-06-18 2020-12-31 COVID-POC1, NCT04563689 Phase Not Applicable Recruiting 1 6 Months 24 Adolfo Contreras, prof, Beatriz Parra, PhD, Juan Gispert, MD, Ruben Leon, PhD, Vanessa Blanc, PhD 2020-10-05
ACPREGCOV: Active Pregnancy Against COVID-19 Coronavirus disease 19 infection, Pregnancy disorder Exercise program alone Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Universidad Politecnica de Madrid Hospital Puerta de Hierro Majadahonda, Hospital Universitario Severo Ochoa, Hospital Vall D'Hebron, University Hospital of Torrejon Spain 2020-08-01 2023-12-31 ACPREGCOV, NCT04563065, UPM-2020-32/33 Phase Not Applicable Recruiting 2 41 Months 280 Aranzazu Martin, Dr, Cristina Silva-Jose, Msc, Cristina Silva-José, MsC, Ignacio Refoyo, Dr, Irene Buhigas, Dr, Irune Alzola, Dr, Javier Coterón, Dr, Javier Gil, Dr, Maia Brik, Dr, Mar Gil, Dr, Miguel Sanchez-Polan, Msc, Rubén Barakat, Rubén Barakat Carballo, Rubén Barakat, Dr, Tirso Perez, Dr, Vanessa Carrero, Dr, Ángeles Blanco, Dr 2020-10-01
XatJove Anoia, as a Tool to Bring Health Services Closer to Teenagers Coronavirus disease 19 infection XatJove Anoia Aplication alone Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs) Jordi Gol i Gurina Foundation Catalan Health Service Spain 2020-10-01 2021-10-11 20/137-P, NCT04562350 Phase Not Applicable Recruiting 1 12 Months 500 Glòria Saüch Valmaña, Josep Vidal-Alaball, PhD, Nuria Carré Llopis, RN, Núria Carré Llopis, RN 2020-10-01
Evaluation of the effect of education in the prevention of covid-19 Coronavirus disease 19 infection protection motivation theory-based educational program alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hamadan University of Medical Sciences Iran 2020-09-22 IR.UMSHA.REC.1399.476, IRCT20200902048598N1 Phase Not Applicable Recruiting 1 200 Dr. Saeed Bashirian, Majid Barati, Roholah Afshar 2020-10-01
Social factors related to COVID 19 Coronavirus disease 19 infection interview alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Tata Memorial Hospital India 2020-10-07 CTRI/2020/09/028090 Phase Not Applicable Not yet recruiting 1 800 Sandeep Tandon 2020-10-01
Role of self sampling in COVID 19 patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute Of Medical Sciences, Rishikesh India 2020-10-05 CTRI/2020/09/028089 Phase Not Applicable Not yet recruiting 1 1350 Dr Amit Kumar 2020-10-01
Effects of Traditional Nasal Saline (Simply Saline) and a Novel Nasal Salt on Aerosol Cleansing Coronavirus disease 19 infection nasal mist calcium salts alone Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Bangalore Baptist Hospital India 2020-10-05 CTRI/2020/09/028084 Phase Not Applicable Not yet recruiting 1 80 Dr Carolin Elizabeth George 2020-09-30
Intubation and ventilatory support in COVID patients: observational study from a tertiary care ICU Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences Jai Prakash Narayan Apex Trauma Centre India 2020-10-02 CTRI/2020/09/028050 Phase Not Applicable Not yet recruiting 1 40 Dr Nishant Patel 2020-09-30
COVID-19: Telemedicine Readiness Coronavirus disease 19 infection telemedicine readiness alone Malaysia 2020-10-15 2021-10-15 56434, NMRR-20-2029-56434 Phase Not Applicable Status not specified 1 12 Months NURIZATI BINTI MAT GHANI 2020-09-30
COVID-19 Spatio-Temporal Modeling Coronavirus disease 19 infection Spatio-Temporal Modeling alone Universiti Putra Malaysia Malaysia 2020-12-01 2022-06-01 56256, NMRR-20-2031-56256 Phase Not Applicable Status not specified 1 18 Months Dr Nur Haizum binti Abd Rahman 2020-09-30
A study to assess aviptadil (inhaled, sarcoidosis/acute lung injury/acute respiratory distress syndrome associated COVID-19), Relief Therapeutics Holding for the treatment of covid-19 and respiratory failure Coronavirus disease 19 infection, Respiratory failure aviptadil (inhaled, sarcoidosis/acute lung injury/acute respiratory distress syndrome associated COVID-19), Relief Therapeutics Holding alone Adrenergic receptor antagonist, VIP receptor agonist NeuroRx Inc, Relief Therapeutics Holding AG Phase Not Applicable Status not specified 0 51 2020-09-29
CAM-Covid-19: Open-Label, Randomized trial of Colchicine, Aspirin and Montelukast in Covid-19 Coronavirus disease 19 infection, Inflammatory disease Standard of Care alone, Variable regimens including Aspirin , colchicine , montelukast sodium Leukotriene D4 antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Indira Gandhi Medical College India 2020-10-31 CAM-Covid-19, CTRI/2020/09/028088 Phase 2 Clinical Not yet recruiting 1 34 Vivek Chauhan 2020-10-05
Phase IIb Clinical Trial of A COVID-19 Vaccine Named Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector) Coronavirus disease 19 infection Ad5-nCoV alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) CanSino Biologics Inc Beijing Institute of Biotechnology, China, Jiangsu Province Centers for Disease Control and Prevention China 2020-09-24 2022-10-20 JSVCT093, NCT04566770 Phase 2b Clinical Recruiting 1 24 Months 481 Fengcai Zhu, MSD, Wenjuan Wang, MSD 2020-10-01
SCREEN: Serology to Covid for Recording Exposures and Evaluating Needs Coronavirus disease 19 infection ELISA alone, biological sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cincinnati Children's Hospital Medical Center US 2020-08-18 2023-12-31 NCT04566965, SCREEN, SCREEN Phase Not Applicable Recruiting 1 40 Months 230 Mary Allen Staat, MD, MPH, Maureen Carolin, Russell Ware, MD, PhD, Sue Poynter Wong, MD, MEd, Teresa Latham 2020-09-30
Co-CLARITY: Convalescent Plasma as Adjunctive Therapy for Hospitalized Patients With COVID-19 Coronavirus disease 19 infection anti-SARS-CoV-2 convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of the Philippines Philippine Council for Health Research and Development Philippines 2020-09-21 2021-06-30 2020-CT0554, Co-CLARITY, NCT04567173, PHRR200824-002868, UPMREB 2020-300-01 Phase 3 Clinical Recruiting 2 9 Months 136 Agnes Evasan, MD, Alric V Mondragon, MD, Anna Flor Malundo, MD, Anne Kristine H Quero, MD, Carlo Francisco N Cortez, MD, Cecile D Dungog, MD, Deonne Thaddeus Gauiran, Deonne Thaddeus Gauiran, Principal Investigator, Deonne Thaddeus V Gauiran, MD, Francisco M Heralde III, PhD, Fresthel Monica M Climacosa, MD PhD, German J Castillo Jr, MD, Ivy Mae S Escasa, MD, Januario Veloso, MD, Jodor Lim, MD, Jose M Carnate Jr, MD, Josephine Anne Lucero, MD, Lynn B Bonifacio, MD, Ma Angelina L Mirasol, MD, Maria Clariza M Santos, MD, Marissa Alejandria, MD MSc, Mark Angelo Ang, MD, Pedrito Y Tagayuna, MD, Rachelle Alfonso, MD, Ruby Anne N King, MD PhD, Sandy Chiong Maganito, MD, Teresita E Dumagay, MD 2020-09-30
ChulaCov19 mRNA Vaccine in Healthy Adults Coronavirus disease 19 infection ChulaCov19 messenger ribonucleic acid alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Chulalongkorn University Faculty of Tropical Medicine, Mahidol University, National Vaccine Institute, Thailand, The National Research Council Of Thailand Thailand 2021-01-31 2021-06-30 CHULAVAC 001, NCT04566276 Phase 1/Phase 2 Clinical Not yet recruiting 1 5 Months 96 Kiat Ruxrungtham, MD, Nitiya Chomchey, PhD, Sivaporn Gatechompol, MD 2020-10-03
Predictive Factors for COVID-19 in Rheumatology Autoimmune disease, Coronavirus disease 19 infection, Musculoskeletal disease disease modifying antirheumatic drug therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundacion Santa Fe De Bogota Colombia 2020-10-31 2021-10-31 FPCOLCOVIDREUMA2020, NCT04567576 Phase Not Applicable Not yet recruiting 1 12 Months 150 Kevin Maldonado Canonn 2020-09-30
PREVAILctDNA: Preventing Viral Pandemic Associated Risk of Cancer Death Using Less Invasive Diagnostic Tests- Liquid Biopsies Biliary cancer, Colorectal tumor, Coronavirus disease 19 infection, Gastrointestinal stromal tumor, Lung tumor, Metastasis, Metastatic bladder cancer, Metastatic pancreas cancer Blood sampling alone, Liquid biopsy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The Royal Marsden NHS Trust UK 2020-06-18 2022-12-31 CCR 5292, NCT04566614, PREVAILctDNA Phase Not Applicable Recruiting 2 30 Months 112 Justin Mencel, MBBS, Naureen Starling, Naureen Starling, MBBS MRCP MD, Scot Davies, CIBiol 2020-09-30
A study to evaluate lipemic serum in patients with CoVID‐19 undergoing lopinavir/ritonavir treatment Coronavirus disease 19 infection, Hypertriglyceridemia lopinavir + ritonavir alone HIV protease inhibitor Male Ministry of Health, Brunei Darussalam Phase Not Applicable Status not specified 0 2 2020-09-29
A trial to evaluate IVIEW-1503 for the treatment of patients with COVID-19 Coronavirus disease 19 infection IVIEW-1503 alone iVIEW Therapeutics Inc University of British Columbia Canada Phase Not Applicable Not yet recruiting 1 2020-09-29
Phase IV study to evaluate the safety and efficacy of Artemisinin- a herbal supplement on COVID-19 subjects Coronavirus disease 19 infection Artemisinin alone, Standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Windlas Biotech Pvt Ltd India 2020-09-30 ARTI/WBPL/P4/2020/01, CTRI/2020/09/028044 Phase 4 Clinical Not yet recruiting 3 120 Dr Antaryami Maharana, Mukesh Kumar 2020-09-30
Clinical study to assess role of Vasa Ghana, Guduchi Ghana and Vasa-Guduchi Ghana in therapeutic management of symptoms in Covid19 Coronavirus disease 19 infection Adhatoda vasica alone,  Tinospora cordifolia alone, Adhatoda vasica plus  Tinospora cordifolia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ministry of Ayush India CTRI/2020/09/028043 Phase 4 Clinical Not yet recruiting 1 50 DR BHAVANA PRASHER, Dr Meera K Bhojani, Prof Tanuja Manoj Nesari 2020-10-01
Seroprevalence of COVID 19 in children Coronavirus disease 19 infection Healthy volunteers accepted, Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Kanchi Kamakoti CHILDS Trust Hospital India 2020-10-05 CTRI/2020/09/028040 Phase Not Applicable Not yet recruiting 1 400 Dr Aishwarya Venkataraman 2020-09-30
Evaluation of severity of chest CT findings in covid 19 patients with pre-existing illness Coronavirus disease 19 infection chest CT findings alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) KIMS Hospital India 2020-10-20 CTRI/2020/09/028087 Phase Not Applicable Not yet recruiting 1 500 Swati Das 2020-09-30
Effect of 12-weeks of Online Sudarshan Kriya Yoga practice on Burnout and Health Parameters among COVID-19 Frontline Warriors Coronavirus disease 19 infection Online Sudarshan Kriya Yoga practice alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute Of Medical Sciences, Rishikesh India 2020-10-08 CTRI/2020/09/028086 Phase Not Applicable Not yet recruiting 1 43 Dr Monika Pathania 2020-09-30
Assessment of Knowledge, Attitude and Practice Towards COVID-19 Pandemic among Hospital Jengka Employees Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Jengka Hospital Malaysia 2020-09-29 2021-02-15 NMRR-20-2044-55325 Phase Not Applicable Not yet recruiting 1 4 Months Mrs. ZURIA IKAZIRA BINTI ZAKARIA 2020-09-30
Mitigation of COVID-19 Clusters in Malaysia Coronavirus disease 19 infection Seberang Jaya Hospital Malaysia 2020-09-24 2020-09-25 NMRR-20-2033-56605 Phase Not Applicable Status not specified 1 DR. MONICA A/P DANIAL 2020-09-30
Evaluation of Atypical imaging features on HRCT CHEST Coronavirus disease 19 infection HRCT alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kalinga Institute of Medical Sciences India 2020-10-20 CTRI/2020/09/028049 Phase Not Applicable Not yet recruiting 1 300 Dr Col Kamal Kumar Sen, Rohit Arora 2020-09-30
Homoeopathy management for covid 19 patients Coronavirus disease 19 infection homoeopathic medicine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Council for Research in Homeopathy Ministry of Ayush India 2020-10-05 CTRI/2020/09/028046 Phase Not Applicable Not yet recruiting 1 100 Dr Sushma Bhtanagar 2020-09-30
Online learning programme for providing cardiopulmonary resuscitation among nurses Cardiac arrest, Coronavirus disease 19 infection Enhancement Training Module on CPR guidelines related to COVID 19 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) All India Institute of Medical Sciences India 2020-09-28 CTRI/2020/09/028045 Phase Not Applicable Not yet recruiting 1 100 POONAM JOSHI 2020-09-30
Double-blind, placebo-controlled, randomized study of the tolerability, safety and immunogenicity of the inactivated whole-virion concentrated purified sorbed vaccine, produced by the Chumakov FSCIRIP Russian Academy of Sciences on volunteers aged 18 to 60 years Coronavirus disease 19 infection inactivated whole-virion concentrated purified coronavirus vaccine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Chumakov Federal Scientific Center for Research and Development of Immune and Biological Products Russian Federation 2020-09-21 2020-12-31 VKI-I/II-08/20 Phase 1/Phase 2 Clinical Status not specified 3 3 Months 300 2020-09-30
Effects of guided imagery on anxiety, muscle pain and vial signs in patients with COVID-19 Anxiety disorder, Coronavirus disease 19 infection, Myalgia headphone-guided mental imagery training alone, muscle relaxation alone, routine care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Oroumia University of Medical Sciences Iran 2020-05-21 2020-08-10 IR.UMSU.REC.1399.102, IRCT20131112015390N5 Phase Not Applicable Completed 1 2 Months 110 Naser Parizad 2020-09-30
An observational case report to determine the drug evaluation and pharmaceutical care in a critically ill COVID-19 patient Coronavirus disease 19 infection drug evaluation alone Science and Technology Agency of Shandong Province Phase Not Applicable Status not specified 0 1 2020-09-29
Clinical trial of trans sodium crocetinate against COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome anti-coronavirus drug therapy alone, trans sodium crocetinate alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Mashhad University of Medical Sciences Iran 2020-10-22 IR.MUMS.REC.1399.414, IRCT20081019001369N7 Phase 2 Clinical Not yet recruiting 1 30 Hossein Hosseinzadeh, Mohsen Tafaghodi, Zahra Javid Arabshahei 2020-09-30
A phase II clinical trial of PSC-01 in the treatment of hospitalized COVID-19 patients Coronavirus disease 19 infection PSC-01 alone Personalized Stem Cells Inc California Institute of Regenerative Medicine Phase 2 Clinical Planned 0 2020-09-28
Coping methods of stress among frontline Healthcare workers Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Jai Prakash Narayan Apex Trauma Centre India 2020-10-05 CTRI/2020/09/028085 Phase Not Applicable Not yet recruiting 1 200 Dr Ridhima Bhatia, Dr Yudhyavir Brahmachari 2020-09-29
A phase I clinical trial of PSC-01 in the treatment of hospitalized COVID-19 patients Coronavirus disease 19 infection PSC-01 alone Personalized Stem Cells Inc California Institute of Regenerative Medicine US Phase 1 Clinical Not yet recruiting 1 20 2020-09-28
Corona Virus Infection Among Liver Transplant Recipients Coronavirus disease 19 infection Electrochemiluminescence immunoassay (ECLIA) alone, blood sampling alone Assiut University Egypt 2020-09-15 2020-12-31 17300475, NCT04565782 Phase Not Applicable Recruiting 1 3 Months 150 Amal A Mahmoud, MD, Bashir A Fadel, MD, Dr. Nahed A. Makhlouf, Mohamed A Medhat, MD, Mohammed A Medhat, MD, Nahed A Makhlouf, Professor, Nahed Makhlouf, Professor, Rasha O Refaay, Professor 2020-09-29
Identification and Characterization of SARS-CoV-2 Specific CD8 T-Cells in Humans Coronavirus disease 19 infection biological sampling alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute on Aging National Institutes of Health Clinical Center US 2020-10-07 2022-09-01 000140-AG, 10000140, NCT04565067 Phase Not Applicable Recruiting 1 22 Months 120 Julia L McKelvey, R.N., Julia McKelvey, Nan-Ping Weng, M.D. 2020-10-03
COV2Base: A Rare Disease by COVID Study Cognitive disorder, Coronavirus disease 19 infection, Rare disease Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Heart Lung and Blood Institute National Institutes of Health Clinical Center US 2020-10-07 2021-09-01 000091-H, 10000091, COV2Base, NCT04564274 Phase Not Applicable Recruiting 1 10 Months 120000 Beth A Kozel, M.D., Sharon Osgood, M.S., Sharon Osgood, R.N. 2020-10-03
Clinical Correlates of COVID-19 Pandemic in Patients With Functional Movement Disorder (FMD) and Parkinson's Disease (PD) Coronavirus disease 19 infection, Movement disorder, Parkinsons disease Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Neurological Disorders and Stroke National Institutes of Health Clinical Center US 2020-10-07 2021-12-31 000159-N, 10000159, NCT04565080 Phase Not Applicable Recruiting 1 14 Months 150 Mark Hallett, M.D. 2020-10-03
CDFCOV19: Study of Famotidine With Vitamins C and D for Pandemic Coronavirus Coronavirus disease 19 infection Variable regimens including famotidine , vitamin C (Nature Made) , vitamin D3 (Nature Made) Histamine H2 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) US 2020-12-01 2021-07-31 CDFCOV19, NCT04565392, PYKONSULT 201 Phase 4 Clinical Not yet recruiting 1 8 Months 216 Robert E Pyke, MD, PhD, Robert Pyke, MD, PhD 2020-09-29
A Phase II trial with access to its eClinical Cloud Suite to help seek the fastest path to effective treatment for COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome eClinical Cloud Suite alone Asklepion Pharmaceuticals LLC Sureclinical Inc Phase 2 Clinical Planned 0 2020-09-29
Clinical Trial of Efficacy, Safety, and Immunogenicity of Gam-COVID-Vac Vaccine Against COVID-19 in Belarus Coronavirus disease 19 infection Sputnik V alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Gamalei Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation Collaborator IPHARMA, LLC Russia, Russian Direct Investment Fund Belarus 2020-09-28 2021-04-10 04-GAM-COVID-VAC-2020-RB, NCT04564716 Phase 3 Clinical Recruiting 8 6 Months 100 Elena Abdolvand, MD, Irina Reutskaya, MD, Ljudmila Filipenko, MD, Natalia Proputnevich, MD, Nikolay Dosta, MD, Roman Plotnikov, Sergey Pimanov, MD, Svetlana Ionina, MD, Zakhar Kulakovskiy, MD 2020-10-04
The effect of dental pulp mesenchymal stem cells in treatment of corona disease Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia human dental pulp-derived mesenchymal stem cells (intravenous, COVID-19 pneumonia/respiratory distress syndrome), Kerman University of Medical Sciences alone, intubation therapy alone, oxygen mask alone, routine usual treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kerman University of Medical Sciences Iran 2020-09-10 IR.KMU.REC.1399.373, IRCT20140911019125N8 Phase 2/Phase 3 Clinical Recruiting 1 120 Abbas Pardakhty, Alireza Farsinejad, Mehrdad Farrokhnia 2020-10-05
A phase I clinical trial of 1c-SApNP for the treatment of SARS-CoV-2 Coronavirus disease 19 infection S2GdeltaHR2-presenting I3-01v9 self-assembling protein nanoparticle (COVID-19), Ufovax alone COVID19 Spike glycoprotein modulator Ufovax LLC Phase 1 Clinical Planned 0 2020-09-28
A phase III clinical trial Sputnik V for the prevention of covid-19 Coronavirus disease 19 infection Sputnik V alone COVID19 Spike glycoprotein modulator Dr Reddy's Laboratories Ltd, Gamalei Institute of Epidemiology and Microbiology, Russian Direct Investment Fund India Phase 3 Clinical Planned 1 2020-10-05
A clinical trial of NLC-001 for the potential treatment of COVID-19 Coronavirus disease 19 infection NLC-001 alone Todos Medical Ltd Israel Phase Not Applicable Planned 1 2020-09-28
A clinical trial to evaluate the efficacy of gRAD-based test for rapid detection of COVID-19 virus Coronavirus disease 19 infection gRAD-based test alone BioPorto Diagnostics A/S Phase Not Applicable Planned 0 2020-09-28
An Observational Study of Neurological Function After COVID-19 Infection Coronavirus disease 19 infection, Neurological disease MRI alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Neurological Disorders and Stroke National Institutes of Health Clinical Center US 2020-10-07 2022-12-01 000094-N, 10000094, NCT04564287 Phase Not Applicable Recruiting 1 25 Months 100 Avindra Nath, M.D. 2020-10-03
O2matic-COVI: Automatic Oxygen Titration With O2matic to Patients Admitted With COVID-19 and Hypoxemic Respiratory Failure Coronavirus disease 19 infection, Hypoxia, Respiratory failure O2matic alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) HS Hvidovre Hospital The Danish National Advanced Technology Foundation Denmark 2020-04-15 2020-05-31 NCT04565106, O2MATIC-COVID, O2matic-COVI Phase Not Applicable Completed 1 1 Month 16 Ejvind Frausing Hansen, Ove Andersen, PhD 2020-09-29
Cord Blood-Derived Mesenchymal Stem Cells for the Treatment of COVID-19 Related Acute Respiratory Distress Syndrome Coronavirus disease 19 infection, Respiratory distress syndrome mesenchymal stem cell therapy (respiratory distress syndrome), MD Anderson Cancer Center alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) MD Anderson Cancer Center National Cancer Institute US 2020-07-29 2021-04-30 2020-0365, NCI-2020-06741, NCT04565665 Phase 1 Clinical Recruiting 1 9 Months 70 Amanda Olson 2020-09-30
Convalescent Plasma Therapy for COVID-19 Patients Coronavirus disease 19 infection convalescent plasma alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Pakistan 2020-05-01 2020-10-30 LGH008, NCT04565197 Phase 0 Clinical No longer recruiting 1 5 Months 20 Dr. M.Irfan Malik, Muhammad Irfan Malik, FCPS 2020-09-29
A prospective study to evaluate the effect of systemic inflammatory response to SARS-CoV-2 on lopinavir and hydroxychloroquine plasma concentrations Coronavirus disease 19 infection hydroxychloroquine plus lopinavir + ritonavir Swiss National Science Foundation Phase Not Applicable Status not specified 0 92 2020-09-28
DIAL-COVID-19: Transmission of COVID-19 Virus Among Patients and Staff in Dialysis Centers Coronavirus disease 19 infection, Kidney dialysis Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Alessandro Manzoni Hospital Italy 2020-09-21 2021-10-31 DIAL-COVID-19, DIAL-COVID-19, NCT04565522 Phase Not Applicable Not yet recruiting 1 13 Months 5000 PierAngela Presta, MD, Simeone Andrulli, MD 2020-09-29
A Study in Healthy Subjects to Assess Bioavailability (Proportion of a Drug Which Enters the Circulation to Have an Active Effect) of Acalabrutinib Tablet and Proton-pump Inhibitor Effect (Members of a Class of Medications That Inhibits in Gastric Acid Production) for Rabeprazole Coronavirus disease 19 infection, Mantle cell lymphoma, Respiratory failure acalabrutinib alone, acalabrutinib plus rabeprazole Btk tyrosine kinase inhibitor, H+ K+ ATPase inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) AstraZeneca plc PAREXEL International Germany 2020-10-07 2020-11-30 D8223C00005, NCT04564040 Phase 1 Clinical Not yet recruiting 1 1 Month 40 AstraZeneca Clinical Study Information Center, Dr. Rainard Fuhr 2020-09-29
Clinical Trial to Investigate the Efficacy and Safety of NuSepin in COVID-19 Pneumonia Patients Coronavirus disease 19 infection, Viral pneumonia HY-209 (sepsis/ulcerative colitis/Alzheimer's disease), Shaperon alone G-protein coupled bile acid receptor 1 agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Shaperon Inc Romania 2020-09-25 2020-11-30 2020-003107-34, NCT04565379, SHAPERON001 Phase 2 Clinical Recruiting 4 2 Months 60 Catalina Luca, Dr./Prof., Cosmina Magdau, Dr., David Song, Iulian Diaconescu, Dr., Olga Caliman-Sturdza, Dr., Seung-Yong Seong, Dr. 2020-10-01
A clinical study with nasally administered foralumab either alone or in combination with orally administered dexamethasone in Brazil for treatment of coronavirus infection Coronavirus disease 19 infection foralumab (nasal, neurodegenerative diseases), Tiziana alone, dexamethasone plus foralumab (nasal, neurodegenerative diseases), Tiziana CD3 antagonist Tiziana Life Sciences PLC Brazil Phase Not Applicable Planned 1 2020-10-05
Follow-up Study on Pulmonary Function and Lung Radiographic Changes in Rehabilitating COVID-19 Patients After Discharge Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Union Hospital Tongji Medical School Huazhong University Of Science & Technology China 2020-05-01 2020kfyXGYJ019, ChiCTR2000038609 Phase Not Applicable Recruiting 1 300 Heshui Shi, Xiaoyu Han 2020-09-30
Study of Particle Life Sciences Formulation in management of COVID-19 Coronavirus disease 19 infection Particle Life Sciences Formulation Capsules alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) India 2020-09-25 CTRI/2020/09/027938, PLS-SF-09/2020 Phase 3 Clinical Not yet recruiting 1 100 Dr Sagar Mandlik, Dr Yogesh Dound 2020-09-29
Comorbidities And Complications Associated With Covid-19 Infection Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assiut University Egypt 2020-10-15 2023-02-25 COVID 19, NCT04563442 Phase Not Applicable Not yet recruiting 1 28 Months 200 Gamal Mohamed Rabee, Mahmoud Gamal Hussein, Mahmoud Gamal hussein 2020-09-28
SegCov: Follow-up and Rehabilitation of Survivors of Severe Coronavirus Disease 2019 (COVID-19) Infection Coronavirus disease 19 infection cardiopulmonary stress test alone, chest tomography alone, pulmonary function test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo Brazil 2020-06-23 2021-12-31 4047553, NCT04563156, SegCov Phase Not Applicable Recruiting 1 18 Months 100 2020-09-28
A phase III clinical trial of Foistar in the treatment of patients with COVID-19 infection Coronavirus disease 19 infection repurposed camostat mesilate (oral, COVID-19), Daewoong/Institut Pasteur Korea/Korea Institute of Radiological and Medical Sciences alone Serine protease inhibitor, Transmembrane serine protease 2 inhibitor, Trypsin inhibitor Daewoong Pharmaceutical Co Ltd 2020-12-31 Phase 3 Clinical Planned 0 2020-09-25
ACC19: Covid19 Post Treatment Restorative Healthcare Coronavirus disease 19 infection Variable regimens including Agastya rasayana , Chyavanaprash , Dasamoolakatutraya kashaya , Indhukantha kashaya , Kooshmanda rasayana , Vyagriyadhi kashaya Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Indian Medicine and Homoeopathy, Ministry of Health and Family Welfare India 2020-10-01 ACC19, CTRI/2020/09/027916 Phase 2 Clinical Not yet recruiting 1 150 Dr J Clarence Davy, Dr Senthiarasi TM 2020-09-28
The SAFE School Hessen study: Early detection of SARS-CoV-2 (COVID-19) in schools in the state of Hesse, Germany Coronavirus disease 19 infection SARS-CoV-2 antigen test alone Deutsche Forschungsgemeinschaft (DFG), German Federal Ministry of Education and Research Germany 2020-09-16 20-899, DRKS00023091, The SAFE School Hessen study Phase Not Applicable Recruiting 1 1000 Sandra Ciesek, Sebastian Hoehl 2020-09-28
SERO-CoV-OLD: COVID-19 Serology and Immunosenescence Coronavirus disease 19 infection COVID-19 neutralizing antibody test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire D Amiens France 2020-09-18 2021-11-30 NCT04563650, PI2020_843_0079, SERO-CoV-OLD Phase Not Applicable Recruiting 1 14 Months 330 Cédric JOSEPH, MD, Etienne BROCHOT, MD, Frédéric BLOCH, Pr, Jean-Philippe LANOIX, MD, Julien MOYET Julien, MD, Julien MOYET, MD 2020-09-28
SARS-CoV-2 IgG and IgM Serologic Assays Coronavirus disease 19 infection Beckman Coulter immunoassay alone, Roche automated immunoassay alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Henry Ford Health System US 2020-08-14 2021-08-31 13839, NCT04562246 Phase Not Applicable Recruiting 1 12 Months 500 Bernard C Cook, Bernard C Cook, PhD, Bernard Cook, Division Head, Chemistry-Pathology, John Zajechowski, BS 2020-09-29
Tele-yoga for prevention and management of COVID-19 Coronavirus disease 19 infection Tele-yoga alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ministry of Ayush India 2020-10-01 CTRI/2020/09/027915 Phase Not Applicable Not yet recruiting 1 136 Dr Manjunath NK, Dr Nagarathna R 2020-09-28
Surveillance of Bala Vriddhikara Bhava (Factors Responsible for Host Immunity) in Covid-19 Subjects Coronavirus disease 19 infection Balavriddhikara Bhava alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Ayurveda India 2020-09-30 CTRI/2020/09/027917 Phase Not Applicable Not yet recruiting 1 200 Dr Meera K Bhojani 2020-09-30
Role, challenges and opportunities of catholic pastoral care as part of 'spiritual care' in the end-of-life setting and under COVID-19 pandemic conditions Coronavirus disease 19 infection expert interviews alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitätsklinikum Freiburg, Klinik für Palliativmedizin Germany 2020-10-15 444/20, DRKS00022925 Phase Not Applicable Not yet recruiting 1 30 Katharina Seibel 2020-09-29
A randomized, crossover, single-center, single-dose, phase I trial to assess EG-009 in healthy subjects for the potential treatment of COVID-19 pneumonia Coronavirus disease 19 infection EG-009, Shenzhen Evergreen Therapeutics alone Healthy volunteers accepted Shenzhen Evergreen Therapeutics Co Ltd US Phase 1 Clinical Not yet recruiting 1 24 2020-09-29
SEQ-COV-PHYSIO: Physiopathology and Sequelae of COVID-19 Infection Coronavirus disease 19 infection, Viral pneumonia blood test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire D Amiens France 2020-09-22 2021-03-31 NCT04563676, PI2020-843-0096, SEQ-COV-PHYSIO Phase Not Applicable Recruiting 1 6 Months 400 Claire ANDREJAK, Pr, Rachel DESAILLOUD, Pr, Valery Salle, MD 2020-09-28
Seroprevalence of SARS-CoV 2 in Asymptomatic Frontline COVID-19 HCWs Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Pakistan 2020-07-01 2020-10-30 LGH002, NCT04563247 Phase Not Applicable No longer recruiting 1 3 Months 700 Amina Asif, MPhilMicro 2020-10-01
A phase II, randomized, multicenter, double-blind, placebo-controlled trial to evaluate the safety of fostamatinib for the treatment of hospitalized COVID-19 patients Coronavirus disease 19 infection fostamatinib alone National Heart Lung and Blood Institute, Rigel Pharmaceuticals Inc Inova Health Care Services US 2020-09-17 Phase 2 Clinical Recruiting 2 60 2020-09-25
Sustained Immunity to SARS-CoV-2 Coronavirus disease 19 infection RT-PCR alone, immunoassay alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Henry Ford Health System US 2020-06-23 2021-06-30 13978, NCT04562285 Phase Not Applicable Recruiting 1 12 Months 500 Bernard C Cook, Bernard C Cook, PhD, Bernard Coo, John Zajechowski, BS 2020-09-28
A phase I clinical trial of PTX-COVID19-B for the potential treatment of COVID-19 Coronavirus disease 19 infection PTX-COVID19-B alone COVID19 Spike glycoprotein modulator Providence Therapeutics Holdings Inc 2020-12-31 Phase 1 Clinical Planned 0 2020-09-25
DuACT: Study of Oral Administration of Ribavirin and Nitazoxamide Versus Placebo in COVID-19 Coronavirus disease 19 infection nitazoxanide plus ribavirin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Witwatersrand South Africa 2020-12-31 2021-03-31 DUACT-101, DuACT, NCT04563208 Phase 2 Clinical Not yet recruiting 1 3 Months 40 Willem Daniel Francois Venter, 2020-09-29
AMABIE-COVID-19: Assessment of the prediction models to alleviate burden of infectious disease in the emergency department-COVID-19 Coronavirus disease 19 infection Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Japanese Association for Acute Medicine Japan 2020-09-24 AMABIE-COVID-19, UMIN000041893 Phase Not Applicable Recruiting 1 784 Atsushi Shiraishi, Shuta Fukuda 2020-09-28
Safety and Immunogenicity Trial of an Oral SARS-CoV-2 Vaccine (VXA-CoV2-1) for Prevention of COVID-19 in Healthy Adults Coronavirus disease 19 infection VXA-CoV2-1 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Vaxart Inc US 2020-09-30 2021-10-31 NCT04563702, VXA-COV2-101 Phase 1 Clinical Recruiting 1 13 Months 48 Josefina Martinez, Priscilla Trejo, Shaily J Garg, Tami Islam, MPH, Youngjun Kim, MD 2020-10-05
Community Applications of the MindShift App Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression MindShift app alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Windsor US, Canada 2020-09-15 2022-10-31 MINDSHIFT, NCT04562948 Phase Not Applicable Not yet recruiting 2 25 Months 250 Lance M Rappaport, Ph.D. 2020-09-28
Group of patients admitted to the emergency department with COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo Brazil 2020-03-14 30417520.0.0000.0068, 4.228.204, RBR-5d4dj5, U1111-1258-1111 Phase Not Applicable No longer recruiting 1 2500 Julio Flavio Marchini 2020-09-28
Clinical Profile and Outcomes of Coronavirus Disease 19 (COVID-19) Patients Who Underwent Hemoperfusion (HP) in a COVID Referral Hospital: A Descriptive Study Coronavirus disease 19 infection hemoperfusion alone Philippine General Hospital Philippines 2020-04-01 2020-09-30 PHRR200915-002928 Phase Not Applicable Not yet recruiting 1 6 Months Chicki Florette C. Uy, Elizabeth S. Montemayor, Jan Andre S. Montemayor, Jen Adrian S. Montemayor, Sheryll Anne Manalili, Sheryll Anne R. Manalili 2020-09-28
REPAVID-19: Reparixin in COVID-19 pneumonia Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia reparixin (oral tablet, COVID-19 associated pneumonia), Dompe alone CXCR1 chemokine antagonist, CXCR2 chemokine antagonist, IL-8 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dompe Farmaceutici SpA Italy 2020-05-06 2020-001645-40, REPAVID-19, REPAVID-19 Phase 2/Phase 3 Clinical Recruiting 1 159 Flavio Mantelli 2020-09-28
Clinical trial of Favipiravir treatment of patients with COVID-19 Coronavirus disease 19 infection, Viral pneumonia favipiravir alone RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hungary 2020-09-17 2020-002728-35, HUN-AVI-01 Phase 3 Clinical Recruiting 1 150 CRO 2020-09-29
Utility of Medihope as an addon therapy for Covid 19 patients Coronavirus disease 19 infection, Respiratory disorder Medihope alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) India 2020-10-02 CTRI/2020/09/027975 Phase 3 Clinical Not yet recruiting 2 880 Dr Rahul Kunkulol 2020-09-28
Clinical Evaluation of Chyawanprash for the prevention of COVID-19 among Health Care Personnel Coronavirus disease 19 infection Chyawanprash alone, Standard Preventive Regimen alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Central Council for Research in Ayurvedic Sciences India 2020-10-15 CTRI/2020/09/027974 Phase 2 Clinical Not yet recruiting 1 200 Dr Satyendra Kumar Sonkar 2020-09-28
HFNC19LGH: High-Flow Nasal Cannula (HFNC) In COVID-19 Patients Coronavirus disease 19 infection, Respiratory disease, Viral pneumonia high-flow nasal cannula alone, high-flow nasal oxygen therapy alone, prone positioning alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Pakistan 2020-05-01 2020-10-30 HFNC19LGH, LGH004, NCT04560257 Phase Not Applicable Recruiting 1 5 Months 30 Dr. M.Irfan Malik, Muhammad Irfan Malik, FCPS, Sardar Al-Fareed Zafar, Sardar Al-Fareed Zafar, FCPS 2020-09-30
An open-label, prospective, comparative study to evaluate the proposed therapy in adults with mild symptomatic COVID-19 patients receiving the standard treatment of COVID infection Coronavirus disease 19 infection Variable regimens including Ascoril LS , cefixime , ivermectin , montelukast sodium Chloride channel modulator, Leukotriene D4 antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) India 2020-09-22 CTRI/2020/09/027944 Phase 3 Clinical Not yet recruiting 1 30 Dr Anita Saibannavar, Dr Dhananjay Lad 2020-09-28
Single arm study of Itolizumab in the treatment of COVID 19 complication Coronavirus disease 19 infection itolizumab alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Biocon Ltd India 2020-09-26 CTRI/2020/09/027941, ITOLI-C19-04-I-01 Phase 4 Clinical Not yet recruiting 7 Dr Anuja Pandit, Dr Atul Gogia, Dr Mahendran, Dr Rosemari De Souza, Dr Subramanian Loganathan, DrChirag Rathod, DrNilesh Mahale, DrRosemarie De Souza, DrSushant Hiraman Meshram, Sivakumar Vaidyanathan 2020-09-29
Prophylactic study of Ashwagandha and HCQ in health care providers Coronavirus disease 19 infection Ashwagandha (Withania somnifera alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ministry of Ayush India 2020-10-03 CTRI/2020/09/028007 Phase 2 Clinical Not yet recruiting 1 400 Anand More 2020-09-28
The SOAR Study: Sources of a Resilient Mindset in Health Professionals During COVID-19 Coronavirus disease 19 infection off semi-structured interviews alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) La Trobe University Australia 2020-09-23 2020-12-02 ACTRN12620000921987p, The SOAR Study Phase Not Applicable Not yet recruiting 1 2 Months 20 Dr Lydia Brown 2020-09-29
GERIA-COVID: Elucidating the Symptomatic, Explanatory and Prognostic Characteristics of Geriatric Patients Hospitalized for COVID-19 Coronavirus disease 19 infection Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Angers France 2020-03-15 2020-07-31 2020/100, AR20-0087V0, GERIA-COVID, NCT04560608 Phase Not Applicable Completed 1 4 Months 255 Cédric ANNWEILER, MD, PhD 2020-09-29
DETECT Schools: DETECT Schools Study: Understanding the impact of COVID-19 in Western Australian Schools Coronavirus disease 19 infection Enhanced COVID-19 index case response alone, SARS-CoV-2 asymptomatic spot testing alone, Survey-based wellbeing assessments alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Telethon Kids Institute The Department of Health Western Australia Australia 2020-05-29 2020-11-09 ACTRN12620000922976, DETECT Schools, DoH20205875 Phase Not Applicable No longer recruiting 2 5 Months 30000 Ms Derry Simpson, Prof Peter Gething 2020-09-29
Clinical Trial to Evaluate the Efficacy, Immunogenicity and Safety of the Inactivated SARS-CoV-2 Vaccine (COVID-19) Coronavirus disease 19 infection COVID-19 vaccine (inactivated, Vero cells/intramuscular), Beijing Biological Products Institute/National Institute for Viral Disease Control and Prevention of Chinese Center for Disease Control and Prevention alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Laboratorio Elea Beijing Biological Products Institute Co Ltd, China National Biotec Group, The Huesped Foundation Argentina 2020-09-16 2021-12-01 BIBP2020003AR, NCT04560881 Phase 3 Clinical Recruiting 4 14 Months 3000 Eduardo Spitzer, B.Sc., Florencia Cahn, MD, Gabriela Aguirre, MSc, Maria I Figueroa, MD, Pablo Bonvehi, MD, Pedro Cahn, MD, Ricardo Ruttimann, MD 2020-10-03
Dental implants in cleft lip and alveolar patients Cleft palate, Coronavirus disease 19 infection cone beam computed tomography (CBCT) alone, dental implant alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Jamia Millia Islamia India 2020-11-01 CTRI/2020/09/027997 Phase Not Applicable Not yet recruiting 1 30 Dr Rizwana Mallick, Dr Srinivas Gosla Reddy 2020-09-28
Assessment of effect of COVID-19 on fatigue and exercise capacity in patients with Covid-19 treated at a government tertiary care hospital Coronavirus disease 19 infection, Fatigue Fatigue Assessment Scale alone, One Minute Sit to Stand test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) B.Y.L Nair Charitable Hospital India 2020-09-30 CTRI/2020/09/027993 Phase Not Applicable Not yet recruiting 1 75 Anagha Mangaonkar, Dr Chhaya Verma, Sayali Mhatre 2020-09-29
Investigator Initiated Study to Evaluate the Effectiveness and Safety of Thymosin α-1 (Tα1) in Moderate COVID-19 Patients Coronavirus disease 19 infection standard of care alone, thymalfasin alone Thymosin receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Innovative Drug Discovery Inc, Kasturba Hospital India 2020-09-25 CTRI/2020/09/027992, IIT_THY_002_20 Phase 2 Clinical Not yet recruiting 1 20 Dr Adarsh Shetty, Dr Om Shrivastava 2020-09-30
A clinical trial of self-amplifying RNA vaccine (im, COVID-19), Imperial College London to assess the safety and effectiveness of delivering the vaccines directly to the respiratory tract of human volunteers, by inhalation through the mouth Coronavirus disease 19 infection self-amplifying RNA vaccine (im, COVID-19), Imperial College London alone COVID19 Spike glycoprotein inhibitor Imperial College London, University of Oxford National Institute for Health Research (NIHR), United Kingdom Research & Innovation Phase Not Applicable Planned 0 2020-09-24
A clinical trial of AZD-1222 to assess safety and effectiveness of delivering the vaccines directly to the respiratory tract of human volunteers, by inhalation through the mouth Coronavirus disease 19 infection AZD-1222 alone COVID19 Spike glycoprotein modulator Imperial College London, University of Oxford National Institute for Health Research (NIHR), United Kingdom Research & Innovation Phase Not Applicable Planned 0 2020-09-24
SECURADOM: Secure Self-monitoring Through a Combination of Connected Objects: Implementation in COVID-19 Patients Monitored at Home Coronavirus disease 19 infection Withings Sleep device alone, Withings Tensiometer device alone, Withings Thermo device alone, Withings smartwatch device alone, home monitoring alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Withings France 2020-09-14 2021-09-14 2020-A00981-38, NCT04560855, SECURADOM Phase Not Applicable Recruiting 4 12 Months 400 David Campo, PhD, Jean-Louis Pépin, Pr, Yang Rui Yu, PhD 2020-09-28
Investigation of Subsequent and Co-infections Associated With SARS-CoV-2 (COVID-19) Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Methodist Health System US 2020-05-30 2021-05-31 033.PHA.2020.A, NCT04561193 Phase Not Applicable Recruiting 2 12 Months 200 Crystee Cooper, DHEd, Ed Dominguez, MD, Matthew Crotty, PharmD, Paola Gregoire, MS, MBA, Ronda Akins, PharmD 2020-09-25
Evaluation of the COVIDSeq Test in Nasal Swab and Saliva From an Asymptomatic Population Coronavirus disease 19 infection COVIDSeq Test (Illumina, Inc) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Illumina Inc Helix BioPharma Corp US 2020-09-11 2020-12-31 COVD-B07-002, NCT04561102 Phase Not Applicable Recruiting 1 3 Months 2500 2020-09-28
Post COVID Syndrome: Clinical Pattern and Functional Assessment Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assiut University Egypt 2020-12-01 2022-01-01 NCT04561141, POSTCOVID SYNDROME Phase Not Applicable Not yet recruiting 1 13 Months 85 Lamia Hassan Shaban, professor, Mostafa Mahmoud 2020-09-28
Evaluate Safety and Pharmacokinetics of HLX-70 in Healthy Adult Volunteers Coronavirus disease 19 infection HLX-70 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Hengenix Biotech Inc Sanyou Biopharmaceuticals (Shanghai), Shanghai ZJ Bio-Tech US 2020-12-09 2021-09-18 HLX70-001US-255086, NCT04561076 Phase 1 Clinical Not yet recruiting 1 9 Months 24 Esther Yoon, MD, Sherry Xu 2020-09-28
Large vessel thrombosis in patients with COVID-19 Coronavirus disease 19 infection, Thrombosis University of Sulaimani Iraq 2020-01-01 2020-08-01 ChiCTR2000038537 Phase Not Applicable No longer recruiting 1 7 Months 7 Fahmi Hussein Kakamad, Hawbash Mohammed-Amin Rahim 2020-09-29
A study of neurological damage in patients recovering from novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Magnetic resonance examination alone Healthy volunteers accepted Anhui Provincial Hospital China ChiCTR2000038471 Phase Not Applicable Recruiting 1 160 Jieping Lu, Wei Xiong, Xiaoling Ding 2020-09-25
Depression, Anxiety and SARS-CoV-2 (Covid-19) Phobia in Post-stroke Patients Anxiety disorder, Coronavirus disease 19 infection, Depression, Phobia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fatih Sultan Mehmet Training and Research Hospital Turkey 2020-06-01 2020-08-10 FSMEAH-KAEK 2020/41, NCT04560413 Phase Not Applicable Completed 2 2 Months 77 Arzu Atici, MD, Duygu Silte Karamanlioglu, MD, Feyza Unlu Ozkan, Assoc Prof, Gulcan Ozturk, MD, Ilknur Aktas, Prof, Pinar Akpinar, Assoc Prof 2020-10-01
Study to Evaluate the Efficacy and Safety of EG-HPCP-03a Compared to DEX in Patients With COVID-19 Pneumonia Coronavirus disease 19 infection, Respiratory disease, Viral pneumonia Standard of care alone, EG-HPCP-03a plus dexamethasone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) 2020-12-31 2021-12-31 HPC-EG-009A-2.1, NCT04561180 Phase 2 Clinical Not yet recruiting 0 12 Months 96 2020-09-25
A clinical trial of Newsight Imaging’s revolutionary spectral device for the diagnosis of Covid-19 Coronavirus disease 19 infection Newsight Imaging’s revolutionary spectral device alone Newsight Imaging Ltd, Sheba Medical Center Phase Not Applicable Recruiting 0 2020-09-24
COVER HCW: COVID-19 Prophylaxis South Africa Coronavirus disease 19 infection, Respiratory disease nitazoxanide alone, sofosbuvir + daclatasvir alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Witwatersrand South Africa 2020-12-31 2021-07-31 COVER HCW, EZ-SS-025, NCT04561063 Phase 2 Clinical Not yet recruiting 2 7 Months 1950 Willem Daniel Francois Vente 2020-09-29
A Study Looking at the Safety and Effectiveness of a COVID-19 Vaccine Plus Adjuvant in South African Adults Coronavirus disease 19 infection Matrix M plus NVX-CoV2373 COVID19 Spike glycoprotein modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Novavax Inc Bill & Melinda Gates Foundation South Africa 2020-08-30 PACTR202009726132275 Phase 2 Clinical Recruiting 6 2904 Gary Albert, Shabir Madhi, Vivek Shinde 2020-09-25
A clinial trial of repurposed azelastine (COVID-19), CEBINA for the treatment of COVID-19 Coronavirus disease 19 infection repurposed azelastine (COVID-19), CEBINA alone Histamine H1 receptor antagonist CEBINA GmbH Phase Not Applicable Planned 0 2020-09-24
TC19LGH: Tocilizumab in COVID-19 Lahore General Hospital Coronavirus disease 19 infection tocilizumab (intravenous), Roche/Chugai alone IL-6 receptor antagonist, IL-6 receptor modulator Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Pakistan 2020-05-01 2020-10-30 LGH001, NCT04560205, TC19LGH Phase 1 Clinical Recruiting 1 5 Months 50 Dr. M.Irfan Malik, Associate Professor, Muhammad Irfan Malik, Muhammad Irfan malik, Sardar Al-Fareed Zafar 2020-09-25
Lung Sequelae Post COVID-19 Survivors Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Tengku Ampuan Afzan Malaysia 2020-09-30 2021-03-30 56268, NMRR-20-2017-56268, PCOV2020 Phase Not Applicable Not yet recruiting 1 6 Months 40 Dr Tan Sin Nee 2020-09-25
Respiratory Function in COVID-19 Survivors Coronavirus disease 19 infection, Respiratory disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) MAHSA University, Universiti Malaysia Sarawak, Universiti Teknologi Mara Malaysia 2020-11-01 2023-10-31 56330, NMRR-20-2011-56330 Phase Not Applicable Not yet recruiting 2 36 Months 386 A/Prof Dr Chai Chee Shee, Dr Benedict Sim, Prof Mohammed Fauzi Abdul Rani 2020-09-25
COVID-19 vaccine visitors Coronavirus disease 19 infection Malaysia 2020-10-15 2021-10-15 56433, NMRR-20-2016-56433 Phase Not Applicable Status not specified 1 12 Months NOR AZIZAH BINTI MOHAMAD NAZRI, Rabiahtul Adawiyah binti Egar 2020-09-25
Evaluation of a COVID-19 Pneumonia CXR AI Detection Algorithm Coronavirus disease 19 infection, Viral pneumonia Chest X-Ray AI Neural Network (RadGen SARS-CoV2 Detection System) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ensemble Group Holdings Hong Kong 2020-03-01 2020-12-31 EN-092020, NCT04561024 Phase Not Applicable No longer recruiting 1 10 Months 4000 2020-09-25
Malaysia I-Share: International Sexual Health and Reproductive (ISHARE) Health during COVID-19: Malaysian Perspective Coronavirus disease 19 infection, Reproductive disorder Institute for Public Health Malaysia 2020-09-19 2023-06-30 55791, Malaysia I-Share, NMRR-20-1998-55791 Phase Not Applicable Status not specified 1 33 Months NORHAFIZAH BTE SAHRIL, Prof. Dr. Low Wah Yun 2020-09-25
FMAB: Body Weight Regulation, Disordered Eating Behaviour, and Experiences of Sexual Harassment in Female Martial Art Athletes Coronavirus disease 19 infection, Eating disorder Healthy volunteers accepted, Female, Adolescents (13-17 yrs), Young Adults (18-44 yrs) Norwegian School of Sport Sciences Ostfold University College, University of Oslo Norway 2020-09-10 2020-12-31 20/00378, FMAB, NCT04559542 Phase Not Applicable Recruiting 1 3 Months 200 Jorunn Sundgot-Borgen, PhD, Professor Jorunn Sundgot-Borgen, Therese F Mathisen, Phd 2020-09-24
The Role of CT Chest Scan in the Pre-anesthetic Assessment of Suspected or Confirmed COVID-19 Patients Coronavirus disease 19 infection, Viral pneumonia Multi-slice CT scan machine alone, Non-enhanced chest CT scan alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tanta University Saudi Arabia 2020-03-01 2020-09-01 CHEST CT SCAN IN COVID-19, NCT04560530 Phase Not Applicable Completed 1 6 Months 76 MOHAMMED FAWZI ALI ABOSAMAK 2020-09-28
A Phase I/IIa clinical trial of K-NK-ID101 in COVID-19 Coronavirus disease 19 infection K-NK-ID101 alone Kiadis Pharma BV Phase 1/Phase 2 Clinical Planned 0 2020-09-24
Evaluation of the COVIDSeq Test in Saliva Specimens From Illumina Personnel Coronavirus disease 19 infection COVIDSeq Test alone, Illumina personnel (Illumina, Inc) alone, saliva sampling alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Illumina Inc Helix BioPharma Corp US 2020-07-13 2020-12-31 COVD-B07-001, NCT04561089 Phase Not Applicable Recruiting 3 5 Months 2000 2020-09-25
RC19LGH: Remdesivir in COVID-19 Lahore General Hospital Coronavirus disease 19 infection remdesivir (Remidia) alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Pakistan 2020-06-01 2020-11-30 LGH003, NCT04560231, RC19LGH Phase 0 Clinical Recruiting 1 6 Months 30 Dr. M.Irfan Malik, Muhammad Irfan Malik, FCPS, Sardar Al-Fareed Zafar, FCPS 2020-09-26
A case-report study evaluating a pediatric inflammatory multisystem syndrome patient with central nervous system involvement and hypocomplementemia following SARS-COV-2 infection Central nervous system disease, Coronavirus disease 19 infection, Inflammatory disease, Kawasaki disease IVIG plus methylprednisolone Male Rambam Health Care Campus Phase Not Applicable Status not specified 0 1 2020-09-25
Biomodulin T in a long-lived population at high risk of COVID-19 infection Coronavirus disease 19 infection Biomodulin T alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Center for Biopreparations (BIOCEN) Ministerio de Salud Publica Cuba 2020-09-21 2020-12-31 GEC2020BMT029, RPCEC00000335 Phase Not Applicable Not yet recruiting 1 3 Months Liliam Rodriguez Rivera, Mary Carmen Reyes Zamora 2020-09-25
PROUDEST: Effects of COVID-19 on pregnancy, childbirth, puerperium, neonatal period and child development: prospective, multicenter cohort study Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Hospital Regional da Asa Norte, University Hospital of Brasilia Brazil 2020-07-01 4.055.854, CAAE: 32359620.0.0000.5558, PROUDEST, RBR-65qxs2, U1111-1253-5244 Phase Not Applicable Recruiting 1 1200 Geraldo Magela Fernandes, Lizandra Paravidine Sasaki, Lícia Maria Henrique da Mota 2020-09-25
An expanded access program to evaluate the efficacy of Zofin in the treatment of COVID-19 patients Coronavirus disease 19 infection Zofin alone, steroids alone, Zofin plus hydroxychloroquine Organicell Regenerative Medicine Phase Not Applicable Status not specified 0 9 2020-09-24
The effect of MMR vaccine in preventing COVID disease 19 Coronavirus disease 19 infection, Measles virus infection, Mumps virus infection, Respiratory tract infection, Rubella virus infection measles/mumps/rubella vaccine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ahvaz University of Medical Sciences Iran 2020-11-19 IR.AJUMS.REC.1399.361, IRCT20200802048266N1 Phase 3 Clinical Not yet recruiting 1 323 Muhammad Badavi, Souri Heidari 2020-09-25
The effect of giving a Drug to block nerves supplying Kidneys to reduce Blood loss during Surgery for removal of Kidney Stones Bleeding, Coronavirus disease 19 infection paravertebral block alone, Variable regimens including fentanyl , glycopyrrolate , isoflurane , midazolam hydrochloride , nitrous oxide , oxygen , propofol, AstraZeneca/Fresenius , ropivacaine , vecuronium , vecurronium Benzodiazepine receptor agonist, Sodium channel inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Rajarajeswari Medical college and Hospital India 2020-10-15 CTRI/2020/09/027909 Phase 2 Clinical Not yet recruiting 1 50 Dr Rashmi 2020-09-29
Evaluation of effects of eucalyptus tablets on the process of Covid-19 disease Coronavirus disease 19 infection eucalyptus soft oral capsule (Barij Essential Oil Company) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Iran University of Medical Sciences Iran 2020-09-22 IR.IUMS.REC.1399.534, IRCT20200913048701N1 Phase 3 Clinical No longer recruiting 1 50 Dr Fateme Tajikrostami, Dr. Seyed Abbas Motavlian, Hossein Shirazi 2020-10-04
RCT, Double-Blind, Placebo to Evaluate the Effect of Zinc and Ascorbic Acid Supplementation in COVID-19 Positive Hospitalized Patients in BSMMU Coronavirus disease 19 infection, Hypoxia, Respiratory failure standard treatment alone, ascorbic acid plus zinc gluconate Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Bangabandhu Sheikh Mujib Medical University Bangladesh 2020-10-01 2021-09-01 BSMMU 2020, NCT04558424 Phase Not Applicable Not yet recruiting 1 11 Months 50 Shohael Mahmud Arafat, FCPS, elora sharmin, MD, sharmin 2020-09-25
NaPro: COVID-19 Study on natural protection against SARS-CoV2 reinfections Coronavirus disease 19 infection biological sampling alone University Hospital, Bonn Deutsche Forschungsgemeinschaft (DFG), German Federal Ministry of Education and Research, Ministerium für Arbeit, Gesundheit und Soziales NRW Germany 2020-09-30 DRKS00023113, Lfd. Nr. 372/20, NaPro Phase Not Applicable Not yet recruiting 2 1250 Hendrik Streeck 2020-09-25
COVID-19 Amyotrophic Lateral Sclerosis (ALS) Registry Coronavirus disease 19 infection, Motor neurone disease Variable regimens including albuterol , dextromethorphan hydrobromide + quinidine sulfate (oral, pseudobulbar affect/ diabetic peripheral neuropathic pain), Avanir Pharmaceuticals , edaravone , riluzole Cytochrome P450 2D6 inhibitor, Metabotropic glutamate receptor 1 antagonist, NMDA receptor antagonist, Nicotinic acetylcholine receptor antagonist, Opioid receptor sigma agonist 1, Sodium channel inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Atrium Health US 2020-10-15 2024-04-30 AH-NSI-COVID19-ALS, NCT04559009 Phase Not Applicable Not yet recruiting 1 42 Months 100 Allison Newell-Sturdivant, MSN, BSN, Erica Gowan, Urvi Desai, MD 2020-09-24
Seroconversion in COVID-19 Recovered Population Coronavirus disease 19 infection serum sampling alone Pakistan 2020-07-01 2020-10-30 LGH006, NCT04558385 Phase Not Applicable No longer recruiting 1 3 Months 275 Amina Asif, MPhilMicro 2020-09-25
A Study To Evaluate The Efficacy And Safety Of a Novel Niclosamide Suspension Formulation For COVID-19 (Niclonex) Coronavirus disease 19 infection niclosamide (suspension, COVID-19), Imuneks Farma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Imuneks Farma Ilaç Sanayi Ve Ticaret AS Turkey 2020-09-28 2021-01-07 NCT04558021, NOV2020/01930 Phase 3 Clinical Recruiting 9 3 Months 200 Aydin Erenmemisoglu, Prof.Dr., Ayse O Mete, Dr., Ayşe Ö Mete, Dr., İlkay Karaoglan, Prof. Dr. 2020-09-28
COVID-19 and Lactating Mothers Coronavirus disease 19 infection biological sampling alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Rochester National Institute of Allergy and Infectious Diseases, New York University US 2020-07-02 2021-04-01 3U01AI131344-04S1, NCT04558320, STUDY00004889 Phase Not Applicable Recruiting 1 9 Months 100 Kirsi Jarvinen-Seppo, Miranda Klein 2020-09-25
Methyl19LGH: Methylprednisolone in COVID-19 Patients Coronavirus disease 19 infection, Lung disease dexamethasone alone, methylprednisolone (Pfizer) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Pakistan 2020-05-01 2020-10-30 LGH005, Methyl19LGH, NCT04559113 Phase 2 Clinical Recruiting 1 5 Months 200 Dr. M.Irfan Malik, Muhammad Irfan Malik, FCPS, Muhammad Irfan malik, FCPS, Sardar Al-Fareed Zafar, FCPS 2020-09-25
T2B! immunity after SARS-CoV-2 Coronavirus disease 19 infection The Netherlands Organisation for Health Research and Development Netherlands 2020-09-09 2022-07-01 METC2020_194, NL8900 Phase Not Applicable Not yet recruiting 1 21 Months 900 Luuk Wieske 2020-09-24
Anxiety and Depression Among Pregnant Women During COVID-19 Pandemic Anxiety disorder, Coronavirus disease 19 infection, Depression Healthy volunteers accepted, Female Assiut University Egypt 2020-10-31 2021-06-30 ADCOVID, NCT04558749 Phase Not Applicable Not yet recruiting 1 8 Months 150 Ahmed Mohamed Abbas 2020-09-24
Pilot Study of a Brief, Scaleable Intervention for Coronavirus (COVID-19) Mental Health Sequelae in College Students Coronavirus disease 19 infection Dialectical Behavioral Therapy (DBT) Skills alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rutgers University US 2020-09-12 2020-12-15 NCT04558411, PRO2020002008 Phase Not Applicable Recruiting 1 3 Months 150 Evan Kleiman, Ph.D., Shireen Rizvi, Ph.D. 2020-09-24
Evaluation of Physical Activity and Quality of Life of Patients With Type 1 Diabetes Mellitus During the Covid-19 Pandemic Coronavirus disease 19 infection, Insulin dependent diabetes Online Survey alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Gazi University Turkey 2020-09-18 2020-12-18 91610558-604.01.02, NCT04558645 Phase Not Applicable Recruiting 1 3 Months 70 Füsun BALOŞ TÖRÜNER, Prof, Meral BOŞNAK GÜÇLÜ, Prof, Zeliha ÇELİK, Zeliha ÇELİK, MSc 2020-09-30
HEIDI-BP-HW: Evaluation of Two Eating Disorders Prevention Interventions in At-Risk Female Students With Body Dissatisfaction Coronavirus disease 19 infection, Eating disorder Body Project (BP) alone, Healthy Weight Program (HW) alone Healthy volunteers accepted, Female, Young Adults (18-44 yrs) School of Health Sciences Geneva France 2020-12-01 2022-02-28 99021, HEIDI-BP-HW, NCT04558073 Phase Not Applicable Not yet recruiting 1 15 Months 90 Isabelle Carrard, PhD, Sophie Bucher Della Torre, PhD 2020-09-24
Impact of a Hybrid Medical Care Model in the Rheumatoid Arthritis Patient-reported-outcomes Measures: A Non-inferiority Study Coronavirus disease 19 infection, Rheumatoid arthritis Alternating face-to-face medical visits and video medical consultations alone, Face-to-face medical visits alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto Nacional de Ciencias Medicas y Nutricion Mexico 2020-10-01 2022-05-31 IRE-3438 20221, NCT04558905 Phase Not Applicable Not yet recruiting 1 20 Months 156 Virginia Pascual Ramos 2020-09-24
Nasal Irrigation to Reduce COVID-19 Morbidity Coronavirus disease 19 infection Nasal lavage alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Augusta University US 2020-09-24 2020-12-31 1603291, NCT04559035 Phase Not Applicable Recruiting 1 3 Months 200 2020-09-27
Genosvid Diagnostic Test for Early Detection of COVID-19 Coronavirus disease 19 infection GENOSVID alone, exhaled breath sampling alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Gadjah Mada Indonesia 2020-04-01 2020-12-31 1.6/2020, NCT04558372 Phase Not Applicable Recruiting 8 9 Months 1543 Akhmad Rusly, MD(Surgeon), MARS, Amalia Setyati, MD(Paed), Antonia M.I. Saktiawati, MD, PhD, Asep S, MD(Anesthesiologist), Budi Pranowo, MD(Paed), MSc, Dewi Indiastari, MD(Internist), Dian K. Nurputra, MD(Paed), M.Sc, Ph.D, Diana Septiyanti, MD(Pulm), PhD, FAPSR, Kuwat Triyana, Prof, Dr.Eng, MSi., Tarsisius Glory, MD, MPH, Theresia Lindawati, MD, Sp.F, Vini Sagita, MD, MPH 2020-09-28
Long-term Characterization of Patients With Severe/Critical Infection by COVID-19 Virus Coronavirus disease 19 infection 6 minute walk test alone, chest radiography alone, spirometry alone, thoracic computed tomography scan alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundacion Clinica Valle del Lili Colombia 2020-10-01 2021-10-01 1631 COVID-LFT, NCT04559100 Phase Not Applicable Not yet recruiting 1 12 Months 112 Fernandez, Sangiovanni 2020-09-24
Personalized Electronic Record Supported Optimization When Alone for Patients With Hypertension- Pilot Study for Remote Medical Management of Hypertension During the COVID-19 Pandemic Coronavirus disease 19 infection, Hypertension Blood pressure monitoring alone, Standard home blood pressure monitor alone, amlodipine alone Calcium channel inhibitor L-type Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Queen Mary University of London Closed Loop Medicine Ltd, Technology Strategy Board UK 2020-09-30 2021-07-31 283209, NCT04559074 Phase 4 Clinical Not yet recruiting 2 10 Months 1000 CVC CTU, David Collier 2020-09-24
The Effectivity and Safety of Favipiravir Compared to Oseltamivir as Adjuvant Therapy for COVID-19 Coronavirus disease 19 infection comorbid therapy alone, oxygen therapy alone, symptomatic antipyretic drug treatment alone, Variable regimens including azithromycin , chloroquine phosphate , favipiravir , hydroxychloroquine , levofloxacin , sulphur-based chloroquine , vitamin C DNA gyrase inhibitor, RNA polymerase inhibitor, Topoisomerase IV inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Indonesia Indonesia 2020-04-16 2020-10-30 20-04-0455, NCT04558463 Phase 3 Clinical Recruiting 1 6 Months 100 Cleopas M Rumende, MD, PhD, Dante S Harbuwono, MD, PhD 2020-09-24
The Relationship Between COVID-19 and Autoimmune Diseases, Lessons From Practice Autoimmune disease, Coronavirus disease 19 infection ClinAmygate Egypt 2020-09-22 2020-10-30 NCT04558203, PR0014 Phase Not Applicable Recruiting 1 1 Month 450 Emad R Issak, MD 2020-09-25
COVID-Impact: 'Psychological IMPACT of COVID-19 on AP-HP Staff' Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-06-12 2020-12-31 APHP200555, COVID-Impact, NCT04558437 Phase Not Applicable Recruiting 1 6 Months 20000 Antoine PELISSOLO, MD-PhD, Isabelle Vivaldo, Pierre WOLKENSTEIN, MD-PhD, Pierre-André Natella, PharmD 2020-09-24
Low-Dose Tenecteplase in Covid-19 Coronavirus disease 19 infection, Lung embolism Variable regimens including enoxaparin sodium , heparin , tenecteplase Low molecular weight heparin, Tissue plasminogen activator stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Cedars-Sinai Medical Center US 2020-09-08 2022-06-30 ML42522, NCT04558125 Phase 4 Clinical No longer recruiting 1 21 Months 45 Victor E Tapson, MD 2020-09-24
OBS COVID: Spanish Registry of Pregnant Women With COVID-19 Coronavirus disease 19 infection, Septic shock, Viral pneumonia PCR based screening program alone Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Asian Ancestry, African Ancestry, Japanese Ancestry Hospital Puerta de Hierro Majadahonda Hosp Univ & Politecn La Fe, Hospital General Universitario Gregorio Marañon, Hospital Universitario 12 de Octubre, La Paz University Hospital (Madrid) Spain 2020-03-01 2021-03-31 55/20, COV20/0021, NCT04558996, OBS COVID Phase Not Applicable Recruiting 1 13 Months 3000 Maria Luisa De la Cruz Conti, PhD, Oscar M Martinez Perez, Epidemiologist, Oscar M Martinez Perez, MD 2020-09-24
CARTESIAN: Covid-19 Effects on Arterial Stiffness and Vascular Aging Coronavirus disease 19 infection, Vascular disease early vascular aging tests alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris INSERM France 2020-09-30 2032-06-30 20.07.24.57438, APHP200762, APHP200762, CARTESIAN, NCT04558450 Phase Not Applicable Not yet recruiting 4 141 Months 360 Athanase BENETOS, PhD, David MONTAIGNE, PUPH, Hakima MANSEUR, MSc, Jérémy BELLIEN, PUPH, Pierre BOUTOUYRIE, MD PHD, Pierre BOUTOUYRIE, PUPH, Rosa Maria BRUNO, MD 2020-09-29
Feasibility of Rapid COVID-19 Testing in Disadvantaged Populations Coronavirus disease 19 infection Community-driven letter mailing alone, Community-driven texting alone, Rapid SARS-CoV-2 testing alone, Real-time polymerase chain reaction assay alone Healthy volunteers accepted Mayo Clinic, Minnesota US 2020-06-03 2021-12-01 20-004046, NCT04558307 Phase Not Applicable Recruiting 2 17 Months 1000 LaPrincess C Brewer, MD, MPH 2020-09-25
An observational, retrospective, cohort study to compare ribavirin therapy with supportive therapy for patients with severe coronavirus disease 2019 (COVID-19) only Coronavirus disease 19 infection ribavirin alone, supportive care alone Fudan University, Huazhong University of Science and Technology Phase Not Applicable Status not specified 0 115 2020-09-30
CONFIDENT: Efficacy of Convalescent Plasma in Patients With COVID-19 Treated With Mechanical Ventilation Coronavirus disease 19 infection, Multiple organ failure, Respiratory failure, Viral pneumonia convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Liege Belgium Health Care Knowledge Centre Belgium 2020-09-01 2022-09-01 2020-003102-31, CONFIDENT, NCT04558476 Phase 2 Clinical Recruiting 16 24 Months 500 Alexander Dumoulin, MD, Axelle Bertand, Benoit Misset, MD,PhD, Benoît Misset, PhD, David Grimaldi, MD, Elisabeth De Waele, PhD, Emmanuel Van Der Hauwaert, MD, Eric Hoste, MD, Isabelle Michaux, PhD, Michaël Piagnerelli, MD, Misset Benoit, Professor, Nathalie De Mey, MD, Philippe Jorens, MD, Pierre François Laterre, MD, Stefaan Vandecasteele, MD, Stoffel Lamote, MD, Stéphane De Wit, PhD, Vincent Fraipont, MD, Walter Swinnen, MD 2020-09-24
A phase III trial to evaluate DWRX-2003 for the treatment of patients with COVID-19 Coronavirus disease 19 infection repositioned niclosamide (refractory lung disease/COVID-19), Daewoong Pharmaceutical/Institut Pasteur Korea alone Daewoong Pharmaceutical Co Ltd, Mankind Pharma Limited Phase 3 Clinical Planned 0 2020-09-28
A phase II trial to evaluate DWRX-2003 for the treatment of patients with COVID-19 Coronavirus disease 19 infection repositioned niclosamide (refractory lung disease/COVID-19), Daewoong Pharmaceutical/Institut Pasteur Korea alone Daewoong Pharmaceutical Co Ltd, Mankind Pharma Limited Phase 2 Clinical Planned 0 2020-09-28
A clinical trial of T-cell-targeted peptide epitope vaccine for the treatment of COVID-19 Coronavirus disease 19 infection T-cell-targeted peptide epitope vaccine (gold nanoparticle, COVID-19), Emergex alone Emergex Vaccines Limited 2020-12-31 Phase Not Applicable Planned 0 2020-10-05
Effects of a Face Mask on Oxygenation During Exercise Coronavirus disease 19 infection Cloth face mask alone, Disposable face mask alone, Progressive step-exercise cycling test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Saskatchewan Canada 2020-09-14 2020-11-10 2201, NCT04557605 Phase Not Applicable Recruiting 1 1 Month 12 Keely Shaw, MSc, Philip Chilibeck, Ph.D., Philip Chilibeck, PhD 2020-09-24
Brief Informational Intervention for COVID-19 Misinformation Prophylaxis Coronavirus disease 19 infection Brief informational infographic alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Indiana University Indiana Clinical and Translational Sciences Institute (CTSI) US 2020-10-31 2021-02-28 INDIANA_CTSI_AGLEY_2020, NCT04557241 Phase Not Applicable Not yet recruiting 1 4 Months 1000 Jon Agley, PhD, MPH 2020-09-24
DEPARTS: Complicated Grief in ICU in the Aftermath of COVID-19 Coronavirus disease 19 infection questionnaire alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire D Amiens Centre Hospitalier Regional Universitaire de Lille, Hospital Boisguillaume France 2020-09-01 2022-09-30 DEPARTS, NCT04554264, PI2020_843_0071 Phase Not Applicable Recruiting 1 25 Months 160 Anne Sophie MOREAU, MD, Axel BASTIEN, MD, Deborah BOYER, MD, François THOMAS, MD, Yoann Zerbib, Yoann Zerbib, MD 2020-09-24
Nurse-led Alcohol Brief Intervention Plus Mobile Personalized Chat-based Support on Reducing Alcohol Use in University Students Alcoholism, Coronavirus disease 19 infection 12-page health warning leaflet alone, AUDIT score interpretation sheet adapted from the Department of Health of Hong Kong alone, Alcohol brief intervention alone, General health through IM Apps alone, Real-time chat-based support through IM Apps alone, Regular messages through Instant Messaging (IM) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The University of Hong Kong Hong Kong 2020-09-30 2022-11-30 CHAT-BASED ABI (UNISTUDENTS), NCT04025151 Phase Not Applicable Not yet recruiting 1 26 Months 770 Siu Long Chau, PhD 2020-09-28
TREAT-MS: Traditional Versus Early Aggressive Therapy for Multiple Sclerosis Trial Coronavirus disease 19 infection, Multiple sclerosis Early Aggressive Therapy alone, Traditional Therapy alone, Variable regimens including alemtuzumab , cladribine , dimethyl fumarate , diroximel fumarate , fingolimod , glatiramer acetate , interferon beta-1a, Biogen , interferon beta-1b, Novartis , natalizumab , ocrelizumab , ozanimod , peginterferon beta-1a (multiple sclerosis), Biogen , rituximab , siponimod fumarate , teriflunomide Adenosine deaminase inhibitor, B-lymphocyte antigen CD20 inhibitor, CD52 antagonist, Cannabinoid receptor antagonist, Cell adhesion molecule inhibitor, Dihydroorotate dehydrogenase inhibitor, Integrin alpha-4/beta-1 antagonist, Interferon beta ligand, Kelch like ECH associated protein 1 modulator, Nuclear erythroid 2-related factor 2 stimulator, Sphingosine-1-phosphate receptor-1 agonist, Sphingosine-1-phosphate receptor-1 modulator, Sphingosine-1-phosphate receptor-3 modulator, Sphingosine-1-phosphate receptor-4 modulator, Sphingosine-1-phosphate receptor-5 agonist, Sphingosine-1-phosphate receptor-5 modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Johns Hopkins University Patient Centered Outcome Research Institute US 2018-05-02 2023-08-01 IRB00143534, NCT03500328, TREAT-MS Phase Not Applicable Recruiting 49 63 Months 900 Aaron Miller, MD, Ahmed Obeidat, MD, Amy Harmala, LPN, Andrew Russo, Andrew Solomon, MD, Angela Aungst, Angela Whitmire, Anna Vaeth, Annette F Okai, MD, Carlo Tornatore, MD, Carolina Ionete, MD, Cedars-Sinai MS Research Coordinator, Chelsie Derr, Claire Riley, MD, Dakota Williams, MS, Daniel Harrison, MD, Deborah Lockridge, RN, BSN, MSCN, CCRC, Dennis Dietrich, MD, Derek Haase, Derrick Robertson, MD, Dunia Gragui, Edward J Fox, MD, PhD, Elisa McGee, Ellen M Mowry, MD, MCR, Ellen M. Mowry, MD, MCR, Emma Mathews, Emmanuelle L Waubant, MD, PhD, Eric C. Klawiter, MD, MSc, Eunice Travis, Evanthia Bernitsas, MD, Gabriel Pardo, MD, Geeta A Ganesh, MD, MPH, Geoffrey Eubank, MD, Gloria Rodriguez, Gloria von Geldern, MD, Hannah Voss, Ingrid Loma-Miller, MD, Irina Radu, MD, James Wymer, MD, Jane Low, MPA, CCRC, Jason Silversteen, DO, Jeanette Lee, Jen Chalayon, MD, Jennifer S. Graves, MD, PhD, MAS, Jennifer Steshyn, Jessica Sagen, MA, Jill Cramer, MD, John W Rose, MD, Ka Ho Wong, Kaho Onomichi, Kathleen Greenbaum, MSN, RN, CCRC, CDE, Kathy Wilkinson, RN, BSN, OCN, CCRP, Katie Doane, Katie Lyons, RN, BSN, CCRC, Kehaunani Hubbard, Kendall Curtis, Kerry Howard, RN, MSCN, Kerry Naunton, RN, MSCN, CCRC, Krupa Pandey, MD, Lana Zhovtis Ryerson, MD, Laura Armstrong, LPN, Lee Ifhar, MSc, Leticia Tornes, MD, Lexie Hackman, Lindsey Maassel, MS, MA-R, Lisa Schmidt, LPN, Lucy Ng, MA, CCRC, Lupe Zuniga-Estrada, Lynn Wheeler, MS, CCRC, Mary Fetter, Megan Esch, MD, Melody Hackett, Michael Hadden, MPA, CCRP, Michael Ko, MD, Micki Moore, Miryam Palomino, Nancy Sicotte, MD, Peiqing Qian, MD, Ram Narayan, MD, Roman Kassa, MD, Rosemarie R. Baligod, RN, BSN, Sabeen Lulu, MD, Sadio Abdul, Samantha O'Dell, Samantha Villa, Samantha Wang, RN, BSN, Sandra Cassard, ScD, Sara Qureshi, MD, Scott D Newsome, DO, Scott D. Newsome, DO, Sharon Lynch, MD, Siddharama Pawate, MD, Stacey Lent, CCRC, Stanley Cohan, MD, PhD, Susan Emrich, MBA, Susan Filomena, Tiffany Ruppert, CCRP, Troy Desai, MD, Uk Sok Shin, Victoria Hope, W. Oliver Tobin, MB, BCh, BAO, PhD, William Kilgo, MD, William Meador, MD, Yanet Babcock, Yang Mao-Draayer, MD, PhD, Yuriko Courtney, CCRC 2020-10-01
CLARITY IBD: Impact of biological therapy on SARS-CoV-2 infection and immunity in patients with inflammatory bowel disease Coronavirus disease 19 infection, Inflammatory bowel disease Exeter home finger prick test kit alone, Roche Elecsys assay alone, infliximab alone, vedolizumab alone Integrin alpha-4/beta-7 antagonist, MAdCAM inhibitor, TNF alpha ligand inhibitor, TNF binding agent Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Royal Devon & Exeter Healthcare NHS Trust F Hoffmann-La Roche AG, Roche Holding AG UK 2020-05-30 2021-10-08 CLARITY IBD, CPMS 46188, IRAS 283251, ISRCTN45176516, RDE CLARITY 2102102 Phase Not Applicable Not yet recruiting 1 16 Months 6970 Ms Bewshea, Prof Tariq Ahmad 2020-09-24
COVID-NA: Changes in emergency department utilitzation during the COVID-19 pandemic Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Charite Universitaetsmedizin Berlin Germany 2020-03-01 COVID-NA, DRKS00023117, EA1/163/20 Phase Not Applicable Recruiting 1 1000000 Martin Möckel 2020-09-24
Impact in the Medical Care Among the Rheumatic Diseases Patients in a Tertiary Hospital in Mexico During the COVID-19 Pandemic Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder, Rheumatoid arthritis Usual medical care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto Nacional de Ciencias Medicas y Nutricion Mexico 2020-07-01 2020-12-31 IRE-3467, NCT04557358 Phase Not Applicable Recruiting 1 6 Months 346 Irazú Contreras, Msc, Virginia Pascual Ramos, Principal Investigator, Virginia Pascual, MD 2020-09-24
EDSAB-HOME: Evaluating home antibody test kits for the detection of coronavirus (COVID-19) antibodies Coronavirus disease 19 infection blood sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Public Health England National Institute for Health Research (NIHR) UK 2020-04-01 2021-06-01 CPMS 45951, IRAS 284980, EDSAB-HOME, ISRCTN56609224 Phase 2 Clinical Recruiting 8 14 Months 3000 Dr David Wyllie 2020-09-23
Evaluation of efficacy of Fixed Ayurvedic Regimen of Giloy Ki Ghan Vati,Tulsi Tablets,Kalmegh Tablets and Dabur Chyawanprash in COVID-19 Coronavirus disease 19 infection Variable regimens including Dabur chyawanprash , Giloy ki Ghanvati , Kalmegh Tablets , Tulsi tablets Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Dabur India Ltd India 2020-09-22 CTRI/2020/09/027914 Phase 2/Phase 3 Clinical Not yet recruiting 1 72 Dr Arun Gupta, Dr Narendra B Mundhe, Dr Sanjay Tamoli 2020-09-30
TURMERIC trial: Transcendental Meditation (TM) to reduce stress and improve immunity of health care providers during COVID-19 pandemic Acute stress disorder, Coronavirus disease 19 infection Transcendental Meditation (TM) alone, regular daily activities alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Medical Sciences India 2020-09-15 CTRI/2020/09/027910, TURMERIC trial Phase 2/Phase 3 Clinical Not yet recruiting 1 80 Dr Hemanga K Bhattacharjee, Rini Vohra 2020-09-23
A prospective/retrospective study to evaluate the safety and efficacy of ruxolitinib in patients with COVID-19 and severe systemic hyperinflammation Coronavirus disease 19 infection, Inflammatory disease ruxolitinib alone Jak1 tyrosine kinase inhibitor, Jak2 tyrosine kinase inhibitor Friedrich Schiller University of Jena Phase Not Applicable Status not specified 0 14 2020-10-01
Pulmonary Manifestations and Management of COVID-19 Pediatric Patients Admitted in a Tertiary Government Hospital Coronavirus disease 19 infection azithromycin alone, convalescent plasma alone, hydroxychloroquine alone, intravenous immunoglobulin alone, lopinavir + ritonavir alone, vitamin D3 alone, zinc sulfate alone HIV protease inhibitor Philippine General Hospital Philippines 2020-07-29 PHRR200915-002937 Phase Not Applicable Recruiting 1 Kevin Bautista, MD, FPPS, FPAPP, Maria Cristina H. Lozada, MD, DPPS, DPAPP, Wright H. Alborote, Wright H. Alborote, MD, DPPS 2020-09-24
Identification of Differences in Breath Components Detected With IMS in Patients Tested on SARS-CoV-2 (COVID-19) Coronavirus disease 19 infection Ion Mobility Spectrometry alone, ultrasound-based spirometer alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) B Braun Melsungen AG Germany 2020-09-30 2021-03-31 HC-N-H-2004, NCT04556318 Phase Not Applicable Recruiting 1 6 Months 100 Christoph Spinner, PD Dr., Study Manager 2020-10-01
RECOVIDS: Functional Recovery From Acute Respiratory Distress Syndrome (ARDS) Due to COVID-19: Influence of Socio-Economic Status Coronavirus disease 19 infection, Psychiatric disorder, Respiratory distress syndrome clinical examination alone, respiratory functional test alone, semi-directive interview alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire Dijon France 2020-09-18 2021-11-30 NCT04556513, QUENOT 2020, RECOVIDS Phase Not Applicable Recruiting 1 14 Months 500 Jean-Pierre QUENOT, Pierre-Louis DECLERCQ 2020-09-23
imPulse Una Full-spectrum, Over Clothing E-stethoscope Coronavirus disease 19 infection Philips Lumify Ultrasound System alone, imPulse Una e-stethoscope alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Johns Hopkins University US 2020-09-22 2020-12-31 00110011, NCT04556149 Phase Not Applicable Not yet recruiting 1 3 Months 30 Ed Fuchs, MBA, Fuchs, MBA, Jumbe, PhD, Kelly Dooley, MD, PhD 2020-09-23
COVID-19 Ad Intervention Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of California Irvine The University of Hong Kong, University of California Los Angeles US 2020-09-29 2022-07-28 COVID-AD, NCT04555122 Phase Not Applicable Not yet recruiting 1 22 Months 52500 Arjuna Dugarte, Arjuna Ugarte 2020-09-24
A case-report study of neonatal early-onset infection with SARS-CoV-2 in a newborn presenting with encephalitic symptoms Coronavirus disease 19 infection, Encephalitis, Viral pneumonia caffeine alone, intravenous fluids alone, paracetamol alone Healthy volunteers accepted, Female Technische Universitat Dresden Phase Not Applicable Status not specified 0 1 2020-09-28
Mindfulness-based Crisis Intervention for COVID-19 Frontline Healthcare Workers During COVID-19 Coronavirus disease 19 infection Mindfulness based intervention alone Healthy volunteers accepted Instituto de Investigación Hospital Universitario La Paz La Paz University Hospital (Madrid) Spain 2020-03-10 2020-04-26 MIND-COVID-19, NCT04555005 Phase Not Applicable Completed 1 1 Month 1000 2020-09-24
CONFIN-AMP: Experience of Lock Down Related to the Covid-19 Epidemic and Its Impact on the Project of Parenthood Anxiety disorder, Coronavirus disease 19 infection, Depression Assisted Reproduction alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Regional Universitaire de Lille France 2020-10-31 2020-12-31 2020-A01810-39, 2020_65, CONFIN-AMP, NCT04556630 Phase Not Applicable Not yet recruiting 1 2 Months 360 Bérengère DUCROCQ, MD 2020-09-24
Determining the Physical Activity Level of Healthy Adults During Pandemic Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Pamukkale University Turkey 2020-04-11 2020-08-20 2020/8/318, NCT04555954 Phase Not Applicable Completed 1 4 Months 205 EMEL TAŞVURAN HORATA, PhD, Emel TAŞVURAN HORATA 2020-09-22
ASPIRE: Performance Evaluation of LumiraDx COVID-19 (SARS-CoV-2) Ag Test Coronavirus disease 19 infection LumiraDx SARS-CoV-2 Ag kit alone LumiraDx UK Ltd US 2020-06-26 2020-12-31 ASPIRE, NCT04557046, S-CLIN-PROT-00032 Phase Not Applicable Recruiting 7 6 Months 400 Andre Gvozden, Christopher Chappel, Daivd Craig, David Craig, Edward Zissman, Kimberley Henderson, Madhavi Ampajwala, Melanie Hoppers, Raechel Lapel, MPH, Robert Rosen 2020-09-24
MIND/COVID-19: Mental Health Impact and Needs Associated With COVID-19: a Comprehensive National Evaluation in Spain Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder, Suicide Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institut Municipal D'Investigació Mèdica (Imim) Fundacio Institut De Recerca De L'Hospital De La Santa Creu I Sant Pau, Fundacion Clinic per a la Recerca Biomédica, Generalitat de Cataluna, Hospital El Bierzo, Hospital General Universitario Gregorio Marañon, Hospital Torrecárdenas, Hospital Universitario 12 de Octubre, Hospital Universitario Araba(Spain), Hospital Universitario Donostia, Hospital Universitario Principe de Asturias, Hospital Vall D'Hebron, Hospital de Cruces, Hospital del Mar, Instituto de Salud Carlos III, Jordi Gol i Gurina Foundation, Parc Sanitari Sant Joan de Déu, Universitat Pompeu Fabra, University of Valencia Spain 2020-05-08 2021-05-31 2020/9203/I, NCT04556565 Phase Not Applicable Recruiting 18 12 Months 16000 Alma D. Martínez de Salazar, Ana González Pinto, Andrés Aragón Peña, Aurora Pérez Zapata, Consol Serra Pujadas, Cristina Rius Gibert, Eduard Vieta, Enric Aragonés Benaiges, Jordi Alonso, MD, Josep M. Haro Abad, José I. Emparanza Knörr, José Ignacio Pijoan Zubizarreta, José María Pelayo Terán, Juan de Dios Molina Martín, M. Isabel Del Cura González, Mara Parellada, Maria Teresa Puig Reixach, Meritxell Espuga Jordana, Mireia Campos Salanova, Nieves López Fresneña, Nieves Plana Farrás, Rafael M. Ortí Lucas, Víctor Pérez Solà 2020-09-23
Stress and Coping Among Health Workers During Covid Acute stress disorder, Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Malabar Cancer Centre India 2020-09-28 CTRI/2020/09/027908 Phase Not Applicable Not yet recruiting 1 600 Jisha Abraham 2020-09-24
Stress of Doctors in Covid era Acute stress disorder, Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Nizam's Institute of Medical Sciences India 2020-10-01 CTRI/2020/09/027907 Phase Not Applicable Not yet recruiting 1 300 Dr M Naveen Kumar, naveenjust@gmail.com 2020-09-23
Autologous whole blood injection as treatment for Covid-19 infection Coronavirus disease 19 infection Autologous whole blood injection alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) India 2020-10-02 CTRI/2020/09/027904 Phase 2 Clinical Not yet recruiting 1 60 Dr M Christopher 2020-09-23
Surgical Consent During the COVID-19 Pandemic Coronavirus disease 19 infection, Surgical procedure breast surgery alone, general surgery alone, vascular surgery alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Medway NHS Foundation Trust UK 2020-04-10 2020-08-14 2021.016N, NCT04556604 Phase Not Applicable Completed 1 4 Months 45 Oloruntobi Rotimi 2020-09-22
SHIFT-UC: A Study With GB-004 in Adult Subjects With Active Ulcerative Colitis (UC) Coronavirus disease 19 infection, Ulcerative colitis GB-004 alone HIF prolyl hydroxylase-2 inhibitor, Hypoxia inducible factor-1 stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gossamer Bio US 2020-09-30 2022-04-30 2020-002306-12, GB004-2101, NCT04556383, SHIFT-UC Phase 2 Clinical Recruiting 4 19 Months 195 Barrett Levesque, MD, Gossamer Bio, Inc, Principal Investigator 2020-10-05
Testing the efficacy and safety of a blood product COVID-19 Hyper-Immuneglobulin (Human) Solution in Participants with Active COVID-19 Coronavirus disease 19 infection anti-SARS-CoV-2 hyperimmune globulin therapy (intravenous, COVID-19), Intas alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Intas Pharmaceuticals Ltd India 2020-09-22 0279-20, CTRI/2020/09/027903 Phase 2 Clinical Not yet recruiting 2 60 Dr Naman Shah, Dr Rajesh Gosavi, Dr Vipul Thakkar, Mr Prashant Modi 2020-10-01
A Review on Ct-value of rRT-PCR among COVID-19 cases in Terengganu Coronavirus disease 19 infection Sultanah Nur Zahirah Hospital Malaysia 2020-10-01 2020-12-31 56400, NMRR-20-1976-56400 Phase Not Applicable Status not specified 1 3 Months 90 Dr Wan Norliyana binti Wan Mahmud 2020-09-24
Epidemiological Analysis Coronavirus disease 19 infection Malaysia 2020-09-28 2020-10-28 56437, NMRR-20-1981-56437 Phase Not Applicable Status not specified 1 1 Month 121 Dr Mohamad Afiq Amsyar Bin Hamedin 2020-09-23
A randomized, double-blind, placebo-controlled, multicenter, phase III clinical study to assess safety and efficacy of favipiravir in the early treatment outpatient setting for adult COVID-19 infections ith mild to moderate symptoms Coronavirus disease 19 infection favipiravir alone RNA polymerase inhibitor Appili Therapeutics Inc US Phase 3 Clinical Planned 1 826 2020-09-22
New Treatment for COVID-19 Using Ethanol Vapor Inhalation Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure asprin plus ethanol vapor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Mansoura University Egypt 2020-10-01 2022-06-01 20.08.79, NCT04554433 Phase 3 Clinical Not yet recruiting 1 20 Months 80 Ragab 2020-09-22
NOXCOVID: A Dose-Escalation and Dose-Expansion Study of NOX-66 in the Treatment of COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome, Sepsis, Septic shock idronoxil (suppository, late-stage prostate cancer/soft tissue sarcoma/cancers/COVID-19-associated diseases), Noxopharm alone CASP8-FADD-like regulator inhibitor, Ecto NOX disulfide thiol exchanger 2 inhibitor, Sphingosine kinase inhibitor, Sphingosine-1-phosphate receptor-1 antagonist, Stimulator of interferon genes protein stimulator, Topoisomerase inhibitor, X-linked inhibitor of apoptosis protein inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Noxopharm Ltd Eastern Europe 2020-09-30 2021-06-30 NCT04555213, NOX66-007, NOXCOVID Phase 1b Clinical Not yet recruiting 0 9 Months 40 Gisela Mautner, MD, PhD 2020-09-24
Hemodynamic Impact on Critical Care Patients With Lung Damage Secondary to COVID-19 Coronavirus disease 19 infection, Lung injury, Respiratory distress syndrome EV1000 alone, HemoSphere alone, radial artery cannulation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Andalusian Network for Design and Translation of Advanced Therapies Edwards Lifesciences Corp Spain 2020-10-01 2021-04-01 FAB-HEM-2020-01, NCT04556864 Phase Not Applicable Not yet recruiting 5 6 Months 67 Francisco Cota Delgado, MD, Francisco Javier Maynar, MD, Javier Ripollés-Melchor, MD, Juan Victor Lorente, Juan Victor Lorente, MD, Manuel Ignacio Monge García, MD, Mario Marquez, MD 2020-09-22
A multicenter, multi-national observational study to evaluate the correlation between COVID-19 infection and stroke risk Coronavirus disease 19 infection, Stroke Geisinger Health System Turkey, Iran, Finland, Europe, Italy, Lebanon, North America, Asia, Brazil, South America, US, Greece, India, New Zealand, Canada Phase Not Applicable Status not specified 11 26175 2020-09-22
CaVaR-Co19: Cardiovascular Risk Stratification in COVID-19 Cardiovascular disease, Coronavirus disease 19 infection COVID-19 test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Oregon Health Sciences University US 2020-06-08 2021-12-31 CaVaR-Co19, NCT04555187, STUDY00021368 Phase Not Applicable No longer recruiting 1 18 Months 60000 Larisa G Tereshchenko, MD, PhD 2020-09-23
COVID-19 Disease Duration and GIT Manifestations. A New Disease Severity Classification. An Egyptian Experience Bacterial infection, Coronavirus disease 19 infection, Gastrointestinal disease Empiric antibiotic therapy alone, anticoagulant therapy alone, Variable regimens including hydroxychloroquine , vitamin c , zinc Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cairo University Egypt 2020-06-01 2020-07-15 1004, NCT04554979 Phase Not Applicable Completed 2 1 Month 199 Ahmed M Abdul Ghani, MD, Hoda M abdel-Hamid, MD, Mahmoud Wahba, MD, Mohamed Tharwat Hegazy, MD, Mona M Hegazy, MD, Omar Ashoush, MD, Rania M Lithy, MD 2020-09-23
Evaluation of primary preventive measures in populations at high risk for novel coronavirus pneumonia (COVID-19) sequelae osteonecrosis of the femoral head -- a prospective, randomized controlled trial Coronavirus disease 19 infection, Osteonecrosis, Viral pneumonia Jianpi Kanggu Granules alone, Xianling Gubao Capsule alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) The Third affiliated Hospital of Beijing Traditional Chinese Medicine University China 2020-08-01 2021-08-01 ChiCTR2000038343, ChiMCTR2000003941 Phase 0 Clinical Not yet recruiting 2 12 Months 120 Chen Weiheng, Xue Zhipeng 2020-09-23
A clinical trial of MP-0423 for the potential treatment of COVID-19 Coronavirus disease 19 infection MP-0423 alone COVID19 Spike glycoprotein inhibitor Molecular Partners AG 2021-06-30 Phase Not Applicable Planned 0 2020-09-24
A phase I trial of MAN-19 to treat complications caused by COVID-19 Coronavirus disease 19 infection MAN-19 alone Tek tyrosine kinase receptor stimulator Q BioMed Inc Phase 1 Clinical Planned 0 2020-09-21
COVIDIG: COVID-19 Hyper-Immunoglobulin Coronavirus disease 19 infection, Viral pneumonia GC-5131A alone Immunoglobulin agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) GC Pharma South Korea 2020-09-20 2021-08-31 COVIDIG, GC5131A-HIG_P0201, NCT04555148 Phase 2a Clinical Recruiting 1 11 Months 60 Kyoung Ran Peck, Kyoung Ran Peck, Dr. 2020-09-22
Global Impact of COVID-19 on Pulmonology Special Units Coronavirus disease 19 infection Assiut University Egypt 2020-09-01 2020-12-30 ASSIUT20, NCT04554251 Phase Not Applicable Recruiting 1 3 Months 100 Aliae Mohamed-Hussein 2020-09-22
Evaluation of Levamisole efficacy in treatment of COVID-19 Coronavirus disease 19 infection Variable regimens including acetaminophen , diphenhydramine , hydroxychloroquine , levamisole Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Shahid Sadoughi University of Medical Sciences and Health Services Iran 2020-04-08 IR.SSU.REC.1399.063, IRCT20190810044500N7 Phase 2 Clinical Recruiting 1 50 Amirreza Roustaei Firouzabad, Fateme Saghafi, Masoud Mirzaei 2020-09-22
A phase II trial to evaluate rabeximod for the treatment of patients with covid-19 Coronavirus disease 19 infection rabeximod alone Cyxone AB Europe 2020-12-31 Phase 2 Clinical Planned 0 300 2020-10-05
Effect of plasmapheresis in the treatment of high-risk covid patients in Qom province Coronavirus disease 19 infection, Hypoxia FFP alone, plasmapheresis alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Ghoum University of Medical Sciences Iran 2020-03-29 IR.MUQ.REC.1399.057, IRCT20160118026097N5 Phase 3 Clinical No longer recruiting 1 60 Hasan adeli, hasan adeli, jamshid vafaeemanesh 2020-09-22
Convalescent Plasma for the Treatment of COVID-19 Coronavirus disease 19 infection COVID 19 Convalescent Plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Houston Methodist US 2020-03-20 2022-06-30 00025121, NCT04554992 Phase 1 Clinical No longer recruiting 1 27 Months 350 Eric Salazar, Eric Salazar, MD, PhD 2020-09-22
CONCOR-Donor: Convalescent Plasma for COVID-19 Research Donor Study Coronavirus disease 19 infection convalescent plasma alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hospital for Sick Children Canada 2020-06-30 2022-03-31 1000070462, CONCOR-Donor, NCT04555109 Phase Not Applicable Recruiting 1 21 Months 1000 Rulan Parekh, MD 2020-09-22
A Trial of GC-4419 in Patients With Critical Illness Due to COVID-19 Adult respiratory distress syndrome, Coronavirus disease 19 infection, Hypoxia, Respiratory failure avasopasem manganese alone Superoxide dismutase stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Galera Therapeutics Inc US 2020-09-09 2021-12-31 COV-4419-201, NCT04555096 Phase 2 Clinical Recruiting 1 15 Months 50 Amanda Sanders, Analyn Howells, George Matuschak, MD, Jon Holmlund, MD 2020-09-23
An observational study to determine the various clinical presentations of COVID 19 disease Coronavirus disease 19 infection clinical presentation analysis alone Zhangnan Hospital Phase Not Applicable Status not specified 0 11 2020-09-21
Periodontal problems in covid-positive but asymptomatic patients Coronavirus disease 19 infection, Periodontal disease Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Brazil 2020-09-07 1/09/2020, RBR-4scq8h, U1111-1257-5921 Phase Not Applicable Recruiting 1 40 Ana Suarez 2020-09-21
A Phase III Clinical Study to assess the Safety and Efficacy of Ayurvedic Tablets combined with the current available medicine and its impact on lab parameters in Subjects with Uncomplicated Moderate COVID-19 infection Coronavirus disease 19 infection BV-4051 alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Bioved Pharmaceuticals Inc India 2020-09-18 CTRI/2020/09/027817 Phase 3 Clinical Not yet recruiting 4 180 Dr Sujay Patil, DrN Kumarasamy, Rajeev Singh 2020-09-22
Study on placenta of women with coronavirus disease 2019 (COVID-19) Coronavirus disease 19 infection Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), African Ancestry India 2020-09-28 CTRI/2020/09/027862 Phase Not Applicable Not yet recruiting 1 150 Dr Ketki S Kulkarni 2020-09-22
Effect of Teleyoga on health care workers involved in Covid 19 duty Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression, Psychiatric disorder Tele yoga intervention alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) AIIMS Jodhpur India 2020-10-01 CTRI/2020/09/027842 Phase Not Applicable Not yet recruiting 1 60 Dr Naveen K H 2020-09-23
SARS-CoV2 infection Survey/2020: An observational, multicenter study on COVID 19 disease to study on HERD immunity Coronavirus disease 19 infection IgM test alone Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) India 2020-09-17 CTRI/2020/09/027881, SARS-CoV2 infection Survey/2020 Phase Not Applicable Not yet recruiting 1 1000 Dr Dhananjay Lad, Dr Vijaykumar Patil 2020-09-22
Epidemiological, Clinical and Molecular Characteristics of Patients With Acute Respiratory Failure Affected by 2019-NCOV Coronavirus disease 19 infection, Respiratory failure Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Istituto Clinico Humanitas Italy 2020-03-16 2023-07-31 2485, NCT04552340 Phase Not Applicable Recruiting 1 40 Months 1500 Maurizio Cecconi 2020-09-21
An observational study to evaluate the clinical characteristics of COVID-19 in patients with abnormal liver test results Coronavirus disease 19 infection National Clinical Research Center for Infectious Disease China Phase Not Applicable Status not specified 1 417 2020-09-21
COVID-Reims: COVID-19 Patient in Reims University Hospital in March to April 2020 Coronavirus disease 19 infection blood sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire de Reims France 2020-08-04 2022-05-31 COVID-Reims, NCT04553575, PO20124* Phase Not Applicable Recruiting 1 21 Months 499 Damien JOLLY, Damien Jolly 2020-09-21
Antibiotic Misuse During COVID-19 Pandemic: A Cross-sectional Survey Addressed to Community Pharmacists Coronavirus disease 19 infection, Prescription drug abuse Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Beni-Suef University Egypt 2020-07-20 2020-09-15 AA86, NCT04553055 Phase Not Applicable Completed 1 1 Month 413 Asmaa Abdelfattah Elsayed, Hoda M Rabie, PHD 2020-09-21
In this study IMMUACTIVE would be compared with an inert substance, as a supplement in treatment of COVID-19 patients Coronavirus disease 19 infection IMMUACTIVE alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Sami Labs Ltd India 2020-09-22 CPL/90/IMM_COVD/I/AUG/20, CTRI/2020/09/027841 Phase Not Applicable Not yet recruiting 3 100 Dr Ganesh Pratap, Dr Jayasree Krishnan c, Dr Kalpesh Shah, Dr Vivek G 2020-09-21
RIFIDS COVID-19 Terengganu Coronavirus disease 19 infection RT-PCR alone Malaysia 2020-09-30 2021-04-30 56040, NMRR-20-1970-56040 Phase Not Applicable Not yet recruiting 1 7 Months Wan Nor Hafizah Binti Wan Baharuddin 2020-09-22
Screening and prevention of osteonecrosis of the femoral head during novel coronavirus pneumonia (COVID-19) recovery Coronavirus disease 19 infection, Osteonecrosis, Viral pneumonia Jianpi Kanggu alone, Jintiange alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) The Third affiliated Hospital of Beijing Traditional Chinese Medicine University China 2020-09-01 2022-09-01 ChiCTR2000038333, ChiMCTR2000003937 Phase 0 Clinical Not yet recruiting 2 24 Months 120 Chen Weiheng, Xue Zhipeng 2020-09-21
Motion Modelling for Sedentary Behavior during the novel coronavirus pneumonia (COVID-19) pandemic: 10-min High Intensity Interval Training (HIIT) with Music Therapy (MT) Coronavirus disease 19 infection, Psychiatric disorder, Viral pneumonia High Intensity Interval Training (HIIT) with Music Therapy (MT) alone, sedentary task alone Healthy volunteers accepted, Young Adults (18-44 yrs) China 2020-08-01 2020-12-31 ChiCTR2000038256 Phase 0 Clinical Recruiting 1 5 Months 118 Liu Jialing 2020-09-21
Establishment of psychological assistance system for the bereaved during the COVID-19 epidemic Coronavirus disease 19 infection, Post traumatic stress disorder, Psychiatric disorder Grief online counselling alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Beijing Normal University China 2020-04-01 2020-12-31 ChiCTR2000038255 Phase Not Applicable Recruiting 1 9 Months 300 Jianping Wang 2020-09-22
COVID-VIT-D: Effect of Vitamin D on Morbidity and Mortality of the COVID-19 Coronavirus disease 19 infection vitamin D alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundación Para La Investigación E Innovación Biosanitaria En El Principado De Asturias (Finba) Hospital Universitario Central de Asturias, Instituto de Investigation Sanitaria del Principado de Asturias Spain 2020-04-04 2020-12-30 2020-019-PF-CAANJ, COVID-VIT-D, NCT04552951 Phase 4 Clinical Recruiting 1 8 Months 80 Jorge B Cannata-Andía, MD PhD, Juan Pérez-Ortega 2020-09-21
A Clinical Trial to Evaluate the effect of an Ayurvedic Regimen administered in (COVID–19) Patients Coronavirus disease 19 infection Variable regimens including Divya Anu Taila , Divya Coronil , Divya Swasari Vati Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Patanjali Research Foundation, Swami Vivekanand Subharti University India 2020-09-28 CTRI/2020/09/027882 Phase Not Applicable Not yet recruiting 1 150 Dr Gaurav Kapil, Dr Shirobhi Sharma 2020-09-21
ConCorD-19: The Containing Coronavirus Disease 19 (COVID-19) Trial Coronavirus disease 19 infection peginterferon beta-1a (multiple sclerosis), Biogen alone Interferon beta ligand Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Pontificia Universidad Catolica De Chile TVW Telethon Institute for Child Health Research Australia, Chile 2020-09-30 2021-12-31 200703013, ConCorD-19, NCT04552379 Phase 3 Clinical Not yet recruiting 2 15 Months 1240 Arturo Borzutzky, MD, Carolina Iturriaga, NP, Cecilia Perret, MD, Diego Garcia-Huidobro, MD,PhD, Eleanor N Fish, PhD, Jose A Castro Rodriguez, MD, PhD, Jose A Castro-Rodriguez, MD,PhD, Stephen Stick, MD, PhD, Stephen Stick, MD,PhD, Tobias Kollmann, MD,PhD 2020-09-21
A Clinical Trial of a Recombinant Adenovirus 5 Vectored COVID-19 Vaccine (Ad5-nCoV) With Two Doses in Healthy Adults Coronavirus disease 19 infection Ad5-nCoV alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institute of Biotechnology the Academy of Military Medical Sciences PLA Zhangnan Hospital China 2020-09-29 2021-06-30 AMMS85-2004, NCT04552366 Phase 1 Clinical Recruiting 1 9 Months 144 Jianying Huang, Ms, Jianyuan Wu, PhD, Lihua Hou, PhD, Xinghuan Wang, MD 2020-09-24
Psychological Impact of Institutional Quarantine as a Precautionary Measure Against COVID-19 Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Dr. Ram Manohar Lohia Hospital India 2020-09-20 2020-10-20 COVID, NCT04552392 Phase Not Applicable Not yet recruiting 1 1 Month 100 Pragya Sharma, PhD 2020-09-21
Omega-3, Nigella Sativa, Indian Costus, Quinine, Anise Seed, Deglycyrrhizinated Licorice, Artemisinin, Febrifugine on Immunity of Patients With COVID-19 Coronavirus disease 19 infection, Immune disorder, Respiratory disease, Viral pneumonia standard protocol based COVID-19 care alone, Variable regimens including Indian Costus , anise seed , artemisinin , deglycyrrhizinated licorice , docosahexaenoic acid , eicosapentaenoic acid , febrifugine , quinine , thymoquinone Young Adults (18-44 yrs) Beni-Suef University College of Pharmacy,Department of Pharmacy Practice,University of Arizona, Department of clinical pharmacy, faculty of pharmacy, Beni-suef univeristy, Maternity and Children Hospital, Makkah, University of Arizona Saudi Arabia 2020-09-20 2020-12-04 DOI: 10.31219/OSF.IO/U56FC, NCT04553705, TQ/OMEGA-3 ON COVID-19 Phase 2/Phase 3 Clinical Recruiting 1 2 Months 200 HASSAN Masmali [consultant of Pediatrics], M.D, HASSAN Masmali, M.D, MOHAMED M ABDELWAHAB GAMALELDIN, Ph.D Candidate, SHAIMAA M NASHAT SAYED ABDELHALIM, Candidate, SHAIMAA M NASHAT SAYED ABDELHALIM, Ph.D Candidate, SHAIMAA M Nashat SAYED ABDELHALIM, Ph.D Candidate 2020-09-21
A trial to evaluate a nasal spray vaccine for COVID-19 Coronavirus disease 19 infection COVID-19 vaccine alone Hong Kong University of Science & Technology China Phase Not Applicable Not yet recruiting 1 2020-09-18
Does dealing with the worldwide COVID-19-pandemic and alcohol stimuli trigger craving for alcohol for people with Alcohol Use Disorder? A comparative Eye-Tracking study Acute stress disorder, Alcoholism, Coronavirus disease 19 infection, Psychiatric disorder Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University Of Mannheim/Heidelberg Germany 2020-09-19 2020-612N, DRKS00023092 Phase Not Applicable Not yet recruiting 1 30 Patrick Bach 2020-09-23
A Phase 1, Followed by a Phase 2, vaccine given Randomly in subjects in different sites to Evaluate the Safety, side effects, and resistance of the Virus Vaccine, BBV152D Administered between the layers of the skin(intradermal) in Healthy Volunteers Coronavirus disease 19 infection SARS-CoV- 2 Virus Vaccine, BBV152D alone Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Bharat Biotech International Ltd India 2020-09-08 BBIL/BBV152D-B/2020 Version: 3.0, CTRI/2020/09/027674 Phase 1/Phase 2 Clinical Recruiting 4 124 Dr Krishna Mohan 2020-09-21
Short-Term Low Dose Corticosteroids for Management of Post covid19 Pulmonary Fibrosis Coronavirus disease 19 infection prednisolone alone, symptomatic treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) South Valley University Egypt 2020-04-01 2020-07-30 NCT04551781, SVU-MED-CHT019420861 Phase 2 Clinical Completed 1 3 Months 450 alaa DR Rashad, MD 2020-09-21
REsCue: Safety and Efficacy of Rayaldee for Treating Mild to Moderate COVID-19 Coronavirus disease 19 infection calcifediol (oral, vitamin D insufficiency), OPKO alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) OPKO Health Inc US 2020-09-30 2021-04-30 CTAP101-CL-2014, NCT04551911, REsCue Phase 2 Clinical Not yet recruiting 1 7 Months 160 Akhtar Ashfaq, MD FACP FASN, Lawrence Reiter, PhD RQAP-GCP 2020-09-21
Effectiveness of Shallomin syrup on patients affected by COVID-19 Coronavirus disease 19 infection Current protocol drug therapy alone, shallomin syrup alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ahvaz University of Medical Sciences Iran 2020-08-10 IR.AJUMS.REC.1398.995, IRCT20200504047295N1 Phase 3 Clinical No longer recruiting 3 90 Afshin Talebi, Mansour Amin, Mohammad Badavi, Mohammad Jafar Yadyad 2020-09-22
ZnCOVID-19: Zinc Versus Multivitamin Micronutrient Supplementation in the Setting of COVID-19 Coronavirus disease 19 infection Centrum Adult alone, zincPreserVision AREDS alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mayo Clinic Foundation US 2020-09-28 2021-05-14 20-004637, NCT04551339, ZnCOVID-19 Phase Not Applicable Recruiting 1 7 Months 4500 Atta Behfar, MD, PhD 2020-09-30
TELEGERIATRY: Telehealth for patients with dementia at the Hospital Universitário Walter Cantidio-UFC Coronavirus disease 19 infection, Dementia telemedicine alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Federal University of Ceara Brazil 2020-06-17 31779920.1.0000.5045, 4.093.069, RBR-9xs978, TELEGERIATRY, U1111-1254-1141 Phase 1/Phase 2 Clinical Recruiting 1 200 Danielle Pessoa Lima, Jarbas de Sá Roriz Filho 2020-09-19
A clinical trial of Sputnik V in children for the treatment of COVID-19 Coronavirus disease 19 infection Sputnik V alone COVID19 Spike glycoprotein modulator Gamalei Institute of Epidemiology and Microbiology Phase Not Applicable Planned 0 2020-09-18
Safety and Efficacy of Ivermectin and Doxycycline in Treatment of Covid-19 Coronavirus disease 19 infection antihistamine therapy alone, Variable regimens including doxycycline hyclate , ivermectin , montelukast sodium , paracetamol , vitamin C , vitamin D Chloride channel modulator, Leukotriene D4 antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bangladesh Medical Research Council (BMRC) Bangladesh 2020-09-30 2020-12-31 31211062020, NCT04551755 Phase 2 Clinical Not yet recruiting 1 3 Months 188 Abdul Basit Ibne Momen, MRCP, Mohammad Tarek Alam, MD 2020-09-19
Pulsed, inhaled nitric oxide (iNO) for the treatment of patients with mild or moderate corona virus disease (COVID-19) Coronavirus disease 19 infection INOpulse alone, high resolution computed tomography (HRCT) alone, inhaled nitric oxide (iNO) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bellerophon Pulse Technologies Belgium 2020-06-22 2020-002394-94, PULSE-IIT-FluidDA-001 Phase 2 Clinical Recruiting 1 6 Clinical Trial Information Desk 2020-09-18
The Effect of COVID-19 Pandemic on Adolescent and Young Adult Cancer Patients and Survivors Acute stress disorder, Cancer, Coronavirus disease 19 infection Young Adults (18-44 yrs) MD Anderson Cancer Center National Cancer Institute US 2020-07-13 2021-12-31 2020-0504, NCI-2020-06609, NCT04551378 Phase Not Applicable Recruiting 1 17 Months 600 Maria Swartz 2020-09-21
Music Therapy in Frontline Healthcare Workers Coronavirus disease 19 infection, Psychiatric disorder Music Therapy alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Simon Fraser University Canada 2020-10-01 2020-11-30 H20-02015, NCT04551274 Phase Not Applicable Not yet recruiting 1 2 Months 20 Glen Chapman, PhD, Ryan CN D'Arcy, PhD, Ryan CN D'Arvy, PhD, Shaun D Fickling, PhD 2020-09-17
Feasibility and Safety of High-intensity Exercise Training in Patients Surviving COVID-19 Coronavirus disease 19 infection Exercise training alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rigshospitalet, Denmark Denmark 2020-09-25 2021-05-01 75068, H-20033733, NCT04549337 Phase Not Applicable Not yet recruiting 1 7 Months 10 Regitse Christensen, MD PhD, Ronan Berg, MD PhD 2020-09-25
The efficacy of bromhexine hydrochloride in the prevention of COVID-19 disease Coronavirus disease 19 infection, Dyspnea, Respiratory distress syndrome, Viral pneumonia bromhexine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tabriz University of Medical Sciences Iran 2020-04-20 IR.TBZMED.REC.1399.553, IRCT20200317046797N7 Phase 2 Clinical No longer recruiting 1 3500 Dr Khalil Ansarin, Dr Mohammad Samiei, Sepideh Zununi Vahed 2020-09-22
CONSCIENCE: Prevalence of COVID-19 (Coronavirus Disease 19) in Pregnant Women on Labor in a Public Hospital in Chile (Coronavirus Disease Covid-19 Pandemic in Chile) Coronavirus disease 19 infection, Parturition, Premature labor Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Hospital San Juan de Dios, Santiago Chile 2020-04-15 2020-07-15 CONSCIENCE, COVID 19 PREGNANCY HSJD CHILE, NCT04551690 Phase Not Applicable Completed 1 3 Months 720 Helga Vera von Bargen, Helga Vera von Bargen, physician 2020-09-21
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Neutralizing Antibody BGB DXP-593 in Participants With Mild-to-Moderate Coronavirus Disease 2019 (COVID-19) Coronavirus disease 19 infection DXP-593 alone COVID19 Spike glycoprotein modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) BeiGene Co Ltd 2020-10-30 2021-02-28 BGB-DXP593-102, NCT04551898 Phase 2 Clinical Not yet recruiting 0 4 Months 180 BeiGene, Zhen Yao, MD 2020-09-21
Safety and Immunogenicity Study of Inactivated Vaccine for Prevention of COVID-19 Coronavirus disease 19 infection CoronaVac alone Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) Dynavax Technologies Corp, Sinovac Research & Development Co Ltd Medigen Vaccine Biologics Corp China 2020-09-28 2021-09-30 NCT04551547, PRO-NCOV-1003 Phase 1/Phase 2 Clinical Not yet recruiting 1 12 Months 552 Hui Jin, Yuliang Zhao, Master 2020-09-21
A trial to evaluate HFB-30132A for the treatment of SARS-CoV-2 infection (COVID-19) patients Coronavirus disease 19 infection HFB-30132A alone Angiotensin converting enzyme 2 inhibitor, COVID19 Spike glycoprotein inhibitor HiFiBio Phase Not Applicable Planned 0 2020-09-17
A phase I trial to evaluate mRNA-based COVID-19 vaccine, Vaxess Technologies for the prevention of COVID-19 Coronavirus disease 19 infection COVID-19 vaccine (MIMIX/sustained-release), Vaxess Technologies alone Vaxess Technologies Inc US Phase 1 Clinical Planned 1 2020-09-18
Study to Evaluate the Safety and Efficacy of Virazole in Hospitalized Adult Participants With Respiratory Distress Due to COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome ribavirin (inhalation solution, respiratory syncytial virus infection), Bausch Health alone Inosine monophosphate dehydrogenase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bausch Health Americas, Inc. 2020-09-30 2021-04-30 BHC-RIB-5401-GL, NCT04551768 Phase 1 Clinical Not yet recruiting 0 7 Months 50 Anya Loncaric, Francisco Figueroa 2020-09-18
Non-invasive Biometric Monitoring in Nursing Homes to Fight COVID-19 Coronavirus disease 19 infection, Viral respiratory tract infection Biostrap wristband alone, Emfit device alone Healthy volunteers accepted US 2020-09-30 2021-02-26 HSA-001, NCT04548895 Phase Not Applicable Not yet recruiting 1 4 Months 30 Martin G Frasch, Martin G Frasch, MD, PhD 2020-09-18
Avigan Trial Coronavirus disease 19 infection favipiravir alone, supportive care alone RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Department of Health, Philippines, University of the Philippines Philippines 2020-09-01 2021-06-30 2020-CT0542, PHRR200911-002930 Phase 3 Clinical Not yet recruiting 1 10 Months 96 Regina P. Berba, MD 2020-09-21
Sleep Quality Among HCWs Coronavirus disease 19 infection, Insomnia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Zagazig University Ministry of Health in Kuwait Egypt 2020-05-19 2020-09-05 2020/1464, NCT04549350 Phase Not Applicable Completed 1 3 Months 217 Ahmad Abbas 2020-09-22
MLK: Montelukast in COVID-19 Coronavirus disease 19 infection Supportive treatment alone, lopinavir + ritonavir plus montelukast sodium HIV protease inhibitor, Leukotriene D4 antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Babol University of Medical Sciences Iran 2020-07-21 IR.MUBABOL.REC.1399.222, IRCT20180624040213N2, MLK Phase 3 Clinical Recruiting 1 114 Hossein Najafzadehvarzi, Reza Ghadimi 2020-09-18
Verification of the efficacy of Bromhexine hydrochloride in treatment of patients with COVID-19 disease Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia bromhexine hydrochloride alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tabriz University of Medical Sciences Ministry of Health and Medical Education, IRAN Iran 2020-09-22 IR.TBZMED.REC.1399.553, IRCT20200818048444N1 Phase 3 Clinical Recruiting 1 1300 Dr. Mohammad Samiei, Khalil Ansarin, Khalil ansarin 2020-09-22
An observational, retrospective, cohort study to investigate differences in manifestations and outcomes of coronavirus disease 2019 (COVID-19) infection between those with and without rheumatic disease: a comparative cohort study from a US 'hot spot' Coronavirus disease 19 infection, Rheumatoid arthritis Massachusetts General Hospital Phase Not Applicable Status not specified 0 156 2020-09-16
TXACOVIDPREV: Antiviral Effects of TXA as a Preventative Treatment Following COVID-19 Exposure Coronavirus disease 19 infection apixaban plus tranexamic acid Factor Xa antagonist Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Alabama at Birmingham US 2020-12-01 2023-03-31 NCT04550338, TXA.COVID.3, TXACOVIDPREV Phase 3 Clinical Not yet recruiting 1 28 Months 100 Timothy J Ness, MD PhD, Timothy Ness 2020-09-17
A first in human, phase I trial to evaluate the safety and pharmacokinetic of BHV-3500 for the treatment of patients with Coronavirus disease 19 infection and migraine Coronavirus disease 19 infection, Migraine zavegepant alone CGRP receptor antagonist Biohaven Pharmaceutical Holding Co Ltd US 2020-09-10 Phase 1 Clinical Recruiting 1 2020-09-16
A study to evaluate efficacy and safety of etoposide treatment adjunctive to immunosuppressants for a small cohort of critically ill COVID-19 acute respiratory distress syndrome (ARDS) patients presenting with systemic hyperinflammation Adult respiratory distress syndrome, Coronavirus disease 19 infection etoposide phosphate alone Topoisomerase II inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Universitario de Burgos Spain Phase Not Applicable Status not specified 1 11 2020-09-16
ASKCOV: Antisense Therapy to Block the Kallikrein-kinin Pathway in COVID-19 Coronavirus disease 19 infection IONIS-PKK-LRx alone KLKB1 gene inhibitor, Plasma kallikrein inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital do Coracao Instituto de Educação e Pesquisa do Hospital Moinhos de Vento, Ionis Pharmaceuticals Inc US 2020-10-31 2021-12-31 ASKCOV, ASKCOV-TRIAL, NCT04549922 Phase 2b Clinical Not yet recruiting 1 14 Months 90 Alexandre B Cavalcanti, Fernando G Zampieri, MD, Samara P Gomes 2020-09-17
VEP-COV: Virucidal Effect of Povidone-Iodine on COVID-19 In-Vivo Coronavirus disease 19 infection povidone-iodine alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dhaka medical college Bangladesh 2020-07-01 2020-10-30 NCT04549376, PIRCC-1131-2020, VEP-COV Phase 2 Clinical Recruiting 1 3 Months 200 Brig. General Dr. AKM Nasir Uddin, MBBS,MPH, Mohammad Jahid Hasan, MBBS,MPH, Mostafa Kamal Arefin, MBBS,FCPS, Prof Sk Nurul Fattah Rumi, MBBS, MS 2020-09-17
POCAH-COVID: Prevalence Of COVID-19 Among Health-workers in a French General Hospital Coronavirus disease 19 infection RT PCR alone, serology testing alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) France 2020-08-03 2021-06-30 NCT04548908, POCAH-COVID, POCAH-COVID19 Phase Not Applicable Recruiting 1 10 Months 1300 Delphine LEMAIRE-BRUNEL 2020-09-17
MISTIC: Infusions of Mesenchymal Stromal Cells in Children With Multisystem Inflammatory Syndrome Coronavirus disease 19 infection, Inflammatory disease Variable regimens including allogenic human cord tissue derived mesenchymal stromal cells (iv, ARDS asssociated with COVID-19), Duke University , cetirizine , hydrocortisone Histamine H1 receptor antagonist Young Adults (18-44 yrs) Duke University US 2020-11-01 2021-02-01 MISTIC, NCT04549285, PRO00106044 Phase 1 Clinical Not yet recruiting 3 3 Months 6 Edwin Horwitz, MD, PhD, Jennifer Baker, RN, Jessica Sun, MD, Joanne Kurtzberg, MD, Mitchell S. Cairo, MD 2020-09-23
Safety, PK and PD of Kamada Anti-SARS-CoV-2 in COVID-19 Coronavirus disease 19 infection, Viral pneumonia plasma-derived anti-SARS-CoV-2 IgG (COVID-19), Kedrion Biopharma/Kamada alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kamada Ltd Israel 2020-08-05 2021-02-28 KAMADA ANTI-SARS-COV-2-001, NCT04550325 Phase 1/Phase 2 Clinical No longer recruiting 4 6 Months 12 Sharon Castro, MSc 2020-09-17
Effect of Wearing Personal Protective Equipment (PPE) on CPR Quality in Times of the COVID-19-pandemic Coronavirus disease 19 infection Cardiopulmonary resuscitation with wearing personal protective equipment (PPE) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Institute of Mountain Emergency Medicine Italy 2020-09-13 2020-12-31 CPR PPE, NCT04548934 Phase Not Applicable Not yet recruiting 1 3 Months 28 Giacomo Strapazzon, MD, PhD, Simon Rauch, MD, PhD 2020-09-17
Survey about SARS-CoV2 / Covid-19 Coronavirus disease 19 infection Switzerland, Austria, Germany 2020-09-21 A 2020-0205, DRKS00023087 Phase Not Applicable Not yet recruiting 3 1000 Hans-Jürgen Thiesen 2020-09-21
SAMILCOV: Study of the Analytical Performance of Different Salivary Self-collection Methods for the Detection of COVID-19 Coronavirus disease 19 infection saliva sampling alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Direction Centrale du Service de Sante des Armees France 2020-09-15 2020-10-15 2020-COVID19-36, NCT04550390, SAMILCOV Phase Not Applicable Recruiting 4 1 Month 2400 Audrey MERENS, MD, Eric GARNOTEL, MD, Frédéric JANVIER, MD, Vincent FOISSAUD, MD 2020-09-29
LOWACM: A low-intervention study of pre-exposure prophylaxis (PrEP) in healthy volunteers at high risk of coronavirus (SARS-CoV-2) infection. Coronavirus disease 19 infection inosine-glutamyl-cysteinyl-glycine disodium plus potassium chloride Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) North-Western State Medical University Russian Federation 2020-04-22 2020-09-02 ISRCTN34160010, LOWACM, MIBVD-19 Phase 2 Clinical Completed 2 4 Months 100 Dr Nataliya Shvetc, Dr Veronika Gomonova, Prof Dubina 2020-09-23
COVID-19 Related Lung Ventilation and Perfusion Injury Asthma, Coronavirus disease 19 infection Airwave Oscillometry alone, Plethysmography alone, Spirometry alone, V/Q SPECT-CT alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) McMaster University Cyclomedica Australia PTY Ltd Canada 2020-09-18 2021-12-31 FIRH002, NCT04549636 Phase Not Applicable Recruiting 1 15 Months 92 Christopher Marriott, MD, PhD, Manali Mukherjee, PhD, Parameswaran Nair, MD, PhD, Sarah Svenningsen, PhD, Terence Ho, MSc, MD 2020-09-25
GEN-COVID: Genetic Bases of COVID-19 Clinical Variability Coronavirus disease 19 infection Genome wide association studies alone, Whole exome sequencing alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Siena ASST Fatebenefratelli Sacco, Azienda Ospedaliera Ospedale Maggiore di Crema, Azienda Ospedaliera Universitaria Senese, Azienda Ospedaliera dei Colli Monaldi-Cotugno-CTO, Azienda Ospedaliera di Perugia, Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia, Azienda USL Toscana Centro, Cardarelli Hospital, Ceinge Biotecnologie Avanzate Scarl, Fondazione IRCCS Policlinico San Matteo, IRCCS AOU San Martino – IST, IRCCS Istituto Giannina Gaslini, IRCCS L Spallanzani, Irccs Casa Sollievo Della Sofferenza, Istituti Ospitalieri Di Cremona, Istituto Auxologico Italiano, Ospedale San Donato, Ospedale dell'Angelo, Ospedale della Misericordia, Policlinico Universitario Agostino Gemelli, University of Modena and Reggio Emilia Italy, Finland 2020-04-08 2026-04-08 16917, GEN-COVID, NCT04549831 Phase Not Applicable Recruiting 2 72 Months 2000 Alessandra Renieri, MD, PhD, Francesca Mari, MD, PhD 2020-09-18
Clinical Phenotype and Outcomes of Inpatients With COVID-19 and Diabetes Coronavirus disease 19 infection, Diabetes mellitus Azienda Ospedaliero-Universitaria di Parma Italy 2020-07-30 2020-12-31 27557, NCT04550403 Phase Not Applicable Recruiting 1 5 Months 700 Alessandra Dei Cas, MD, PhD, Raffaella Aldigeri, MSc, Riccardo Bonadonna, MD, PhD, Tiziana Meschi, MD 2020-09-17
The Impact of Lifestyle Changes on Non-COVID Deaths Coronavirus disease 19 infection Lifestyle alteration alone Healthy volunteers accepted Jiangsu Provincial People’s Hospital China 2020-09-30 2020-10-31 NCT04550312, XYFY2020-KL142-01 Phase Not Applicable Recruiting 2 1 Month 80000 Chenzong Li, PHD, Ming Chu, PHD, ming chu, PHD, minglong chen, PHD 2020-09-17
A phase I Study of GIGA-2050 for the potential treatment of COVID-19 Coronavirus disease 19 infection GIGA-2050 alone GigaGen Inc Phase 1 Clinical Planned 0 2020-09-16
Recombinant New Coronavirus Vaccine (CHO Cells) to Prevent SARS-CoV-2 Phase I Clinical Trial (>/= 60 Years Old) Coronavirus disease 19 infection, Respiratory disease recombinant new coronavirus vaccine alone Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Anhui Zhifei Longcom Biopharmaceutical Co Ltd China 2020-08-19 2021-12-31 LKM-2020-NCV03, NCT04550351 Phase 1/Phase 2 Clinical Recruiting 1 16 Months 50 Fang Jun Li, Undergraduate, fangjun Li 2020-09-21
M15: The March 15 Study: Examining the impacts and recovery from the March 15 2019 Christchurch Mosque attacks in people most directly exposed and their adult family members Agoraphobia, Anxiety disorder, Bipolar disorder, Coronavirus disease 19 infection, Depression, Obsessive compulsive disorder, Panic disorder, Post traumatic stress disorder, Psychotic disorder, Social phobia semi-structured diagnostic interview alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Otago Health Research Council of New Zealand New Zealand 2020-09-28 ACTRN12620000909921, M15, M15, U1111-1255-8902 Phase Not Applicable Not yet recruiting 1 600 A/Prof Caroline Bell 2020-09-29
A phase II/III study to evaluate the safety and efficacy of UB-612 for the potential prevention of COVID-19 infection Coronavirus disease 19 infection UB-612 alone COVID19 Spike glycoprotein modulator, HLA class I antigen modulator, HLA class II antigen modulator DASA (US) Covaxx Brazil Phase 2/Phase 3 Clinical Planned 1 2020-09-16
COL: Corona Onderzoek Limburg Coronavirus disease 19 infection questionnaire alone, venepuncture alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Netherlands 2020-09-10 2020-12-31 COL, METC 20-071, NL8889 Phase Not Applicable Not yet recruiting 1 3 Months 10000 Nicole Dukers-Muijrers 2020-09-17
The psychological well-being and health-related quality of life of patients admitted to the hospital with COVID-19 Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Franciscus Gasthuis & Vlietland BeterKeten Netherlands 2020-05-28 2021-09-30 2020-042, NL8882 Phase Not Applicable No longer recruiting 1 16 Months 250 Johan Vlake 2020-09-17
Study on Incidence of Elective Surgery Postponed During COVID-19 Pandemic in Geriatric Population Coronavirus disease 19 infection, Psychiatric disorder, Surgical procedure elective surgery alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Malaya Malaysia 2020-06-22 2020-12-31 2020623-8801, NCT04547218 Phase Not Applicable Recruiting 1 6 Months 150 Dhurgka Ramasamy, Hui Min Khor, Pui San Loh, FANZCA 2020-09-20
Inpatient Treatment With Anti-Coronavirus Immunoglobulin (ITAC) Coronavirus disease 19 infection hyperimmune intravenous immunoglobulin (hIVIG) plus remdesivir COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Minnesota International Network for Strategic Initiatives in Global HIV Trials (INSIGHT), National Institute of Allergy and Infectious Diseases, National Institutes of Health UK, Denmark, Argentina, US 2020-09-30 2021-07-31 INSIGHT 013, NCT04546581 Phase 3 Clinical Not yet recruiting 4 10 Months 500 Edward Gardner, MD, Eileen Denning, Jacqueline Nordwall, James Neaton, PhD, Jens Lundgren, MD, DMSc, Marcelo Losso, MD, Sarah Prett, MD 2020-09-17
NSpectroCovid: Study of Morphological, Spectral and Metabolic Manifestations of Neurological Complications in COVID-19 Patients Brain injury, Coronavirus disease 19 infection Magnetic Resonance Spectroscopy (MRS) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire D Amiens France 2020-09-08 2022-05-31 NCT04546737, NSpectroCovid, PI2020_843_0087 Phase Not Applicable Recruiting 1 20 Months 20 Jean-Marc CONSTANS, Pr, Jean-Marc Constans, Pr 2020-09-18
Biomodulin T in the elderly for protection in events of local transmission of COVID-19 Coronavirus disease 19 infection Biomodulin T alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Biopreparations Center Ministerio de Salud Publica Cuba 2020-09-11 2020-12-31 GEC2020BMT028, RPCEC00000334 Phase Not Applicable Not yet recruiting 1 3 Months Luis Philip Heredia Guerra, Mary Carmen Reyes Zamora 2020-09-16
Evaluation and Promotion of Adolescents Mental Health Under the COVID-19 Coronavirus disease 19 infection, Psychiatric disorder Psychology teaching alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Shenzhen University China 2020-09-07 2020-12-31 ChiCTR2000038069 Phase 1 Clinical Recruiting 1 3 Months 180 Qiaomin Huang, Xinli Chi 2020-09-16
PLACOVID: Convalescent Plasma for Severe COVID-19 Patients Coronavirus disease 19 infection best supportive care alone, convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital de Clinicas de Porto Alegre Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul Brazil 2020-07-16 2021-10-31 2020-0158, NCT04547660, PLACOVID Phase 3 Clinical Recruiting 1 15 Months 160 Alexandre P Zavascki, PhD, Júlia P Portich, MD, Leo Sekine, PhD 2020-10-04
A trial to evaluate DS-2319 for the treatment of patients with COVID-19 Coronavirus disease 19 infection DS-2319 alone Serine protease inhibitor Daiichi Sankyo Co Ltd Japan 2021-03-31 Phase Not Applicable Planned 1 2020-09-15
Intravenous Immunoglobulins for the Treatment of Covid-19 Patients: a Clinical Trial Coronavirus disease 19 infection IVIG, Amson Vaccine and Pharma Ltd alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Health Sciences Lahore University of Lahore, Main Campus Pakistan 2020-09-15 2020-11-15 NCT04548557, UNIVERSITYHSL-IVIG Phase 3 Clinical Not yet recruiting 1 2 Months 60 Fridoon J Ahmad, Ph.D, Fridoon Jawad Ahmad, PhD, Gibran Sheikh, PhD, Hassan Ahmad Khan, M.Phil, Javed Akram, MBBS,FRCP,MRCP, Javed Akram, MBBS,FRCS,MRCP, Muhammad Akram Tariq, PhD, Riffat Mehboob, PhD, Riffat o Mehboob, PhD, Syed Amir Gilani, PhD, riffat mehboob, Ph.D 2020-09-16
Study to Evaluate the Safety and Efficacy of Liquid Alpha-1 Proteinase Inhibitor (Human) in Hospitalized Participants With Coronavirus Disease (COVID-19) Coronavirus disease 19 infection Prolastin alone, standard of care medical treatment alone Alpha 1 proteinase inhibitor, Serine protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Grifols Therapeutics Inc, USA 2020-09-30 2021-09-30 GC2006, NCT04547140 Phase 2 Clinical Not yet recruiting 0 12 Months 100 Elsa Mondou, Susan Sorrells 2020-09-16
The Validity of Modern Mobile Applications in Management of COVID-19 Home Isolation Patients: a Survey for Health Care Professionals Coronavirus disease 19 infection mobile application use alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ain Shams University Egypt 2020-09-14 2021-01-31 75 / 2020, NCT04548492 Phase Not Applicable Not yet recruiting 1 4 Months 175 Mona Ammar 2020-09-16
Psychodiagnostic Screening in U-Examinations Coronavirus disease 19 infection, Psychiatric disorder U7a Screening alone, U8 Screening alone, U9 Screening alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitätsklinikum Hamburg-Eppendorf German Ministry of Health, Universitätsklinikum Schleswig-Holstein Germany 2020-10-01 DRKS00022553, LPEK-0117 Phase 4 Clinical Recruiting 2 5670 Silke Pawils 2020-09-16
TASC-3B: Trace element ATORG Study COVID-19 in Berlin, Bavaria, and Baden-Württemberg: Characterization of COVID-19 infections using parameters of the immune system and trace element status Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia antibody test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Klinikum Aschaffenburg Charite Universitaetsmedizin Berlin, University of Heidelberg, University of Zurich Germany 2020-06-22 20033, DRKS00022294, TASC-3B, U1111-1254-2975 Phase Not Applicable Recruiting 1 300 Raban Heller 2020-09-16
Evaluation of the possibility to gain specimen for SARS-CoV-2 PCR from Aerosol/droplets with a sugar matrix that is applied to a face mask Coronavirus disease 19 infection Pharyngeal swabs alone, SARS-CoV-2 PCR alone, face mask alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Jena Germany 2020-09-09 2020-1877-BO, DRKS00023033 Phase 2 Clinical Recruiting 1 10 Andreas Kortgen 2020-09-16
A Study to Evaluate Safety and Efficacy of Convalescent Methylene Blue Treated (MBT) Plasma From Donors Recovered From Coronavirus Disease 2019 (COVID-19) Coronavirus disease 19 infection convalescent anti-SARS-CoV-2 MBT plasma alone, standard medical treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Grifols SA Grifols Therapeutics Inc, USA Spain 2020-04-29 2020-12-31 2020-001299-14, GC2003, NCT04547127 Phase 2 Clinical Recruiting 9 8 Months 100 Adrian Alegre, MD, Cristobal Galban, MD, Elsa Mondou, Jesus Caballero, MD, Juan j Jimenez, MD, Manuel Quintana, MD, Miguel Sanchez, MD, Mireia Torres, Pilar Llamas, MD, Rafael Manez, MD, Ricard Ferrer, MD 2020-09-16
Strength and course of the SARS CoV-specific immune response after infection Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institut für Virologie, Universitätsklinikum Leipzig Germany 2020-09-09 352/20-ek, DRKS00023047 Phase Not Applicable Recruiting 1 60 Christian Jassoy 2020-09-17
Coronary heart disease management during the Corona Pandemic (COVID-19) Acute stress disorder, Coronavirus disease 19 infection, Ischemic heart disease structured disease management program (DMP-CHD) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Leipzig Germany 2020-09-15 397/20-ek, DRKS00023001 Phase Not Applicable Recruiting 1 400 Anne Schrimpf, Markus Bleckwenn 2020-09-16
The role of attentional bias in relation to health anxiety and health practices among cancer patients during the outbreak of the novel coronavirus (COVID-19) Anxiety disorder, Coronavirus disease 19 infection Questionnaire survey alone The University of Hong Kong Hong Kong 2020-04-15 2020-12-31 HKUCTR-2899, UW 20-254 Phase Not Applicable Not yet recruiting 1 8 Months 410 HKUCTR Administrator, Ms. Wing-lam Danielle Ng 2020-09-18
CIS: COVID-19 infection survey of the UK general population Coronavirus disease 19 infection swabs testing alone Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Oxford NIHR Biomedical Research Centre, Oxford, NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Public Health England, The Scottish government, Welsh Government UK 2020-04-14 2023-04-23 CIS, CPMS 46962, IRAS 283248, ISRCTN21086382 Phase Not Applicable Recruiting 2 36 Months 500000 Prof SarahWalker 2020-09-21
CoPS: COVID-19 Persistence in Stool Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Quadram Institute Bioscience Norfolk and Norwich University Hospitals NHS Foundation Trust UK 2020-09-08 2022-06-30 CoPS, NCT04546776, QIB05/2020 Phase Not Applicable Recruiting 2 21 Months 200 Arjan Narbad, BSc, PhD, Ngozi Franslem-Elumogo, MBBS, DTM&H, FRCPath 2020-09-16
CovEx: Recovery of Exertion Ability Following COVID-19 Infection in Military Staff Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Direction Centrale du Service de Sante des Armees France 2020-09-30 2023-03-31 2020-COVID19-30, CovEx, NCT04548505 Phase Not Applicable Not yet recruiting 1 30 Months 100 Alexandra MALGOYRE, MD, PhD 2020-09-16
A Randomized, Controlled, Feasibility Study of Emotional Well-being of Adolescents Undergoing a Mindfulness Training During COVID-19 Coronavirus disease 19 infection Training for Awareness, Resilience, and Action (TARA) alone Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs) University of California San Francisco US 2019-10-18 2020-05-20 19-29083 (B), NCT04548544 Phase Not Applicable Completed 1 7 Months 21 Olga Tymofiyeva, PhD 2020-09-16
Engaging Patients in Colon Cancer Screening Decisions During COVID-19 Colon tumor, Coronavirus disease 19 infection Shared Decision Making alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Massachusetts General Hospital Patient Centered Outcome Research Institute US 2020-09-10 2021-05-30 2020P001579-2, NCT04548531 Phase Not Applicable Recruiting 1 8 Months 800 Karen Sepucha, PhD 2020-10-01
Telerehabilitation in Oncology Patients Cancer, Coronavirus disease 19 infection Therapeutic Exercise and Education alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Malaga Spain 2020-07-01 2020-12-31 NCT04547634, TELECLUB_CAM Phase Not Applicable Recruiting 1 6 Months 30 Dr. Antonio 2020-09-17
A retrospective, case-series trial to study the variation over time of several biomarkers, demonstrated to be predictors of poor prognostic, in subjects successfully treated with tocilizumab for severe COVID-19: results of a multidisciplinary collaboration Coronavirus disease 19 infection tocilizumab (intravenous), Roche/Chugai alone IL-6 receptor antagonist, IL-6 receptor modulator Hôpital Nord Franche-Comté Phase Not Applicable Status not specified 0 40 2020-09-16
Breath Analysis for SARS-CoV-2 in Infected and Healthy Subjects Coronavirus disease 19 infection Breath analysis alone, Foam cuffed oxygen catheter alone, Multicapillary column coupled ion mobility spectrometry alone, Nasal air sampling alone, PCR alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Klinikum Bayreuth Klinik und Institut für Nuklearmedizin Germany 2020-09-14 2021-04-30 IMS COVID-19, NCT04547114 Phase Not Applicable Recruiting 1 7 Months 200 Claus Steppert, MD, Thomas Bollinger, MD 2020-09-16
Awake-Prone Positioning Strategy for Hypoxic Patients With COVID-19 Coronavirus disease 19 infection, Respiratory failure Awake-Prone Positioning Strategy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Atrium Health US 2020-06-14 2020-09-30 06-20-03E, NCT04547283 Phase Not Applicable Recruiting 1 3 Months 40 Stephanie Taylor, MD 2020-09-16
A case-report study evaluating imatinib therapy in patients with CoVID-19 Coronavirus disease 19 infection, Pneumonia imatinib alone Abl tyrosine kinase inhibitor, Bcr protein inhibitor, Kit tyrosine kinase inhibitor, PDGF receptor antagonist, Signal transduction protein inhibitor Female Hospital Universitario de Fuenlabrada Phase Not Applicable Status not specified 0 1 2020-09-16
Safety and Performance Evaluation of Seraph 100 in Treatment of Patients With COVID-19 Coronavirus disease 19 infection, Infectious disease, Multiple organ failure, Respiratory distress syndrome Antibiotic therapy alone, Extracorporal therapy alone, Seraph 100 Microbind Affinity Blood Filter, Exthera Medical alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) ExThera Medical Europe BV ExThera Medical LLC US, Germany, Netherlands 2020-10-15 2021-04-15 CP022, NCT04547257 Phase Not Applicable Not yet recruiting 3 6 Months 42 Herwig Gerlach, Prof., Jens Schirrmacher, PhD, Natascha de Jong 2020-09-17
A clinical study of Carragelose in combination with the ivermectin for prophylaxis against covid-19 infection Coronavirus disease 19 infection inhalation therapy (carragelose, viral pneumonia/COVID-19), Marinomed plus ivermectin Chloride channel modulator Healthy volunteers accepted Marinomed Biotechnologie GmbH Argentina Phase Not Applicable Status not specified 1 229 2020-09-15
A randomized, controlled trial to examine the effectiveness of convalescent plasma in treating children infected with COVID-19 Coronavirus disease 19 infection convalescent plasma alone Childrens Hospital of Philadelphia Phase Not Applicable Planned 0 2020-09-15
pVAC: Safety and Immunogenicity Trial of Multi-peptide Vaccination to Prevent COVID-19 Infection in Adults Coronavirus disease 19 infection Variable regimens including CoVac-1 , Montanide ISA 51 , XS-15 CD4 agonist, T-cell surface glycoprotein CD8 stimulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Tubingen 2020-09-30 2021-12-20 NCT04546841, P-PVAC-SARS-COV-2, pVAC Phase 1 Clinical Not yet recruiting 0 14 Months 36 Helmut Salih, Prof. MD, Juliane Walz, PD MD 2020-09-25
Effect of wearing N 95 mask along with surgical mask in health care workers in covid era Coronavirus disease 19 infection N95 mask alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Sanjay Gandhi Postgraduate Institute of Medical Sciences India 2020-10-01 CTRI/2020/09/027787 Phase Not Applicable Not yet recruiting 1 50 Dr Ashish Kumar Kannaujia 2020-09-16
AMC19: Ayurvedic Management of Covid 19 patients Coronavirus disease 19 infection Variable regimens including Bharangyadi kashaya , Guduchi paaneeyam , Sudharshanavati , Thaleesadi choornam Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Indian Medicine and Homoeopathy India 2020-10-01 AMC19, CTRI/2020/09/027786 Phase Not Applicable Not yet recruiting 1 60 Dr J Clarence Davy, Dr Ramaraju, Dr Sunil Roy R 2020-09-17
CHILL: Trial of Therapeutic Hypothermia in Patients With ARDS Atelectasis, Coronavirus disease 19 infection, Pulmonary edema, Respiratory distress syndrome Hypothermia alone, Neuromuscular blockade alone, atracurium alone, cisatracurium besilate alone, vecuronium alone Nicotinic acetylcholine receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Maryland Baltimore County KAI Research, United States Department of Defense US 2020-10-01 2024-05-31 CHILL, NCT04545424, W81XWH2010432 Phase 2b Clinical Not yet recruiting 14 44 Months 340 Abhijit Duggal, MD/MSc/MPH, Bhakti Patel, MD, Carl B Shanholtz, MD, Gerarad Criner, MD, Gerard Criner, MD, Jared Greenberg, MD, Jeffrey D Hasday, MD, John Reillt, MD, John Reilly, MD, Jonathan Sevransky, MD, Lioudmila Karnatovskaia, MD, Lioudmilla Karnatovskaia, MD, Luis Cardenas, DO/PhD, Mark Yoder, MD, Matthew Barrett, DO, Michael Baram, MD, Michael L Terrin, MD/MPH, Nathaniel Marchetti, DO, Rachel Scheraga, MD, Richard Oekler, MD/PhD, Robert S Stephens, MD, Robert Walter, MD, Samuel A Tisherman, MD, Sean Forsythe, MD, Sunit Singla, MD, Sunit singla, MD, Whittney Warren, DO 2020-09-16
Case Control study to check the effect of Measles vaccine in prevention of COVID-19 Coronavirus disease 19 infection Measles vaccine alone Healthy volunteers accepted, Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Serum Institute of India Ltd India 2020-09-21 CTRI/2020/09/027785, MV-CCS-01 Phase Not Applicable Not yet recruiting 1 548 Dr Malangori Parande, Dr Nilesh S Gujar, Dr Prasad Kulkarni 2020-09-16
SODACAN: Efficacy of sofosbuvir and daclatasvir in ambulatory patients with coronavirus disease Coronavirus disease 19 infection Sovodak (Fanavaran Rojan Mohaghegh Daru Co) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tehran University of Medical Sciences Iran 2020-09-10 IR.TUMS.DDRI.REC.1399.014, IRCT20200831048568N1, SODACAN Phase 3 Clinical Recruiting 1 2000 Ali Ali Asgari, Shahin Merat 2020-09-16
A trial to evaluate convalescent plasma in children with life-threatening cases of COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome convalescent plasma alone Childrens Hospital of Philadelphia Agency for Healthcare Research and Quality, Alex's Lemonade Stand Foundation, American Academy of Allergy Asthma and Immunology, Cookies for Kids' Cancer, National Cancer Institute, National Institute of Allergy and Infectious Diseases, The Leukemia & Lymphoma Society, Wellcome Trust - Burroughs Wellcome Fund Phase 2 Clinical Status not specified 0 4 2020-09-15
Impact of strutured telephone teleorientation on the health of elderly during the COVID-19 pandemic Coronavirus disease 19 infection Structured Telephony Orientation alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Brazil 2020-08-15 35367520.6.0000.5470, 4.177.093, RBR-35vwq9, U1111-1254-6143 Phase Not Applicable Recruiting 1 300 Gustavo Akerman Augusto 2020-09-22
Effect of Diphenhydramine Compound in COVID-19 Coronavirus disease 19 infection diphenhydramine alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Karaj University of Medical Sciences Iran 2020-08-22 IR.ABZUMS.REC.1399.079, IRCT20200504047298N3 Phase 3 Clinical Recruiting 1 120 Mohammad Noorisepehr, Zeinab Siami 2020-09-16
External Ocular Manifestations Among Patients Diagnosed with Coronavirus Disease 2019 (COVID-19) in a Referral Center in the Philippines Coronavirus disease 19 infection Philippine General Hospital Philippines 2020-05-01 2021-01-01 PHRR200911-002933 Phase Not Applicable Recruiting 1 8 Months 72 Alyssa Louise Basisto Pejana, Aramis B. Torrefranca Jr., MD, Ma. Dominga Padilla, MD 2020-09-15
Symptoms and Wellbeing of People Infected With Covid-19 Virus in Iceland Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Landspitali University Hospital Iceland 2020-07-01 2020-09-01 LSH-20-002, NCT04546191 Phase Not Applicable Completed 1 2 Months 1580 Brynja Ingadottir, PhD, Helga Jonsdottir 2020-09-17
Inactivated vaccine, COVID-19 Coronavirus disease 19 infection National Institutes of Health Malaysia 2020-09-14 2022-06-30 55005, NMRR-20-1956-55005 Phase Not Applicable Status not specified 1 21 Months Dr ROZAINANEE MOHD ZAIN 2020-09-15
A case-report study presented with COVID-19 through 18F-FDG PET/CT in an asymptomatic patient Coronavirus disease 19 infection 18F-FDG alone, PET/CT alone, azithromycin alone, levofloxacin alone, lopinavir + ritonavir alone, low-molecular-weight heparin alone DNA gyrase inhibitor, HIV protease inhibitor, Topoisomerase IV inhibitor Male Universita Degli Studi G D`Annunzio Chieti Phase Not Applicable Status not specified 0 1 2020-09-14
The effect of dexamethasone in the treatment of high-risk COVID-19 patients Coronavirus disease 19 infection, Hypoxia dexamethasone alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ghoum University of Medical Sciences Qom University of Medical Science Iran 2020-03-29 IR.MUQ.REC.1399.085, IRCT20160118026097N4 Phase 3 Clinical No longer recruiting 1 60 Ehsan sharifipour, Hasan adeli, Jamshid vafaeemanesh, hasan adeli 2020-09-15
Effect of ethanol and DMSO in prophylaxis and treatment of COVID-19 Coronavirus disease 19 infection dimethyl sulfoxide (German Merck) plus ethanol (German Merck) Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shahrood University of Medical Sciences Iran 2020-08-22 IR.SHMU.REC.1399.091, IRCT20200727048217N1 Phase 3 Clinical Recruiting 1 610 Dr. Mohammad Hasan Emamian, Moslem Jafarisani 2020-09-15
Dental practices in COVID-19 Coronavirus disease 19 infection, Dental caries Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shree Krishna Hospital India 2020-09-23 CTRI/2020/09/027782 Phase Not Applicable Not yet recruiting 1 1600 Aalap Prajapati 2020-09-15
A prospective, randomized, double-blind, placebo-controlled clinical study to evaluate the efficacy and safety of ES-16001 as an adjunct to standard of care treatment on mild to moderate COVID-19 positive subjects undergoing treatment for COVID-19 in Hospital Quarantine (Dedicated Covid Health Centre) Coronavirus disease 19 infection ES-16001 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) GENECELL CO LTD India 2020-09-19 CTRI/2020/09/027775 Phase 2 Clinical Not yet recruiting 2 60 Dr Madhu MS, DrJang Yul Kwak, Subham Dutta 2020-09-16
Views regarding dental facilities and the manner in which patients wants to use dental facilities during COVID 19 in a hospital setting Coronavirus disease 19 infection, Tooth disease Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Medical Sciences India 2022-09-22 CTRI/2020/09/027769 Phase Not Applicable Not yet recruiting 1 375 Harsh Priya 2020-09-16
A clinical trial of SPOR-COV for the preventive treatment for COVID-19 Coronavirus disease 19 infection SPOR-COV alone Destiny Pharma Ltd, SporeGen Ltd Technology Strategy Board Phase Not Applicable Planned 0 2020-09-17
A study that demonstrates performance of the BD Veritor System for Rapid Detection of SARS-CoV-2 Assay was equivalent to that of the Quidel Sofia 2 SARS Antigen Fluorescent Immunoassay (AFI) Coronavirus disease 19 infection BD Veritor System alone, Quidel Sofia 2 SARS Antigen Fluorescent Immunoassay alone BD Technologies Phase Not Applicable Status not specified 0 361 2020-09-14
A study to assess use of angiotensin converting enzyme inhibitors (ACE-I)/angiotensin receptor blockers (ARBs) in managing serious clinical symptoms in COVID-19 patients Coronavirus disease 19 infection angiotensin converting enzyme inhibitors (ACE-I) alone, angiotensin receptor blockers (ARBs) alone African Ancestry Berg Pharma LLC University of Oxford, Virginia Commonwealth University Phase Not Applicable Status not specified 0 2020-09-14
A diagnostic test to assess SARS-CoV-2 viral proteins that determines which COVID-19 patients are most likely to become critically ill Coronavirus disease 19 infection Single Molecule Array (Simoa) SARS-CoV-2 antigen test alone American Association for Clinical Chemistry US Phase Not Applicable Status not specified 1 64 David R. Walt, PhD 2020-09-14
CHARTER-MT: Nebulized Heparin in Patients With Severe COVID-19 Coronavirus disease 19 infection, Hypoxia, Respiratory disease Aerogen Solo vibrating mesh nebulizer (Aerogen) alone, invasive mechanical ventilation alone, standard care alone, unfractionated heparin alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The Australian National University UK, Australia, Spain, US, Ireland 2020-10-31 2022-06-30 CHARTER META-TRIAL, CHARTER-MT, NCT04545541 Phase 2/Phase 3 Clinical Not yet recruiting 5 20 Months 202 Frank MP van Haren, MD, PhD, Frank van Haren 2020-09-15
ABC19 study: Outpatient treatment of COVID-19: Impact of comorbidities on hospital admissions and other treatment decisions Coronavirus disease 19 infection Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Germany 2020-09-20 ABC19 study, Aktenzeichen: E-01-20200804, DRKS00023014 Phase Not Applicable Not yet recruiting 2 500 Philipp Jaehn 2020-09-15
A Study to Evaluate the Safety, Tolerability and Immunogenicity of UB-612 COVID-19 Vaccine Coronavirus disease 19 infection UB-612 alone COVID19 Spike glycoprotein modulator, HLA class I antigen modulator, HLA class II antigen modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Covaxx Taiwan 2020-09-25 2021-08-31 NCT04545749, V-122 Phase 1 Clinical Recruiting 1 11 Months 60 Chang-Yi Wang, Ph.D., Joanna Hung, Kao-Pin Hwang, M.D., Ph.D, Kao-Pin Hwang, M.D., Ph.D., Po-Chang Lin, M.D., Wen-Yuan Lin, M.D., Ph.D. 2020-09-30
A compassionate use program to evaluate CYNK-001 for the treatment of patients with severe COVID-19 and on ventilator support Coronavirus disease 19 infection CYNK-001 alone Celularity Inc US Phase Not Applicable Status not specified 1 2020-09-14
SISPIG: Assessment of effect of steam inhalation, saline gargling and povidone iodine gargling on reduction of symptoms and prevention of spread of COVID 19 Coronavirus disease 19 infection povidone iodine alone, povidone iodine gargling alone, saline gargling alone, steam inhalation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bangalore Medical College and Research Institute India 2020-09-16 CTRI/2020/09/027687, SISPIG Phase Not Applicable Not yet recruiting 1 80 Dr shobha 2020-09-14
To determine whether diabetes in COVID-19 patients is associated with more complications Coronavirus disease 19 infection, Diabetes mellitus Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gujarat Cancer Society Medical college hospital and research centre India 2020-09-20 CTRI/2020/09/027686 Phase Not Applicable Not yet recruiting 1 100 Dr Shams Kanuga 2020-09-14
Clinical Study to Investigate Safety and Efficacy of ImmunoSEB and ProbioSEB Coronavirus disease 19 infection ImmunoSEB plus ProbioSEB CSC3 Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Chirayu Medical College and Hospital Advanced Enzymes Technologies Ltd India 2020-09-16 CTRI/2020/09/027685, PROCLIN_COVID-005_Version 1 Phase Not Applicable Not yet recruiting 1 40 Dr Rohit Parate 2020-09-14
Protective effect of re-vaccination with BCG against COVID-19 in healthcare workers – A pilot study Coronavirus disease 19 infection BCG alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) SGT University Indian Council of Medical Research India 2020-09-15 CTRI/2020/09/027684 Phase 3 Clinical Not yet recruiting 1 400 Dr Dharampal Singh Sudan 2020-09-14
Impact of COVID-19 pandemic era on the outcome, morbidity, and mortality of Acute Care Surgery patients Coronavirus disease 19 infection Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mahidol University Thailand 2020-07-18 TCTR20200901001 Phase Not Applicable Completed 1 61 Chonlada Krutsri 2020-09-14
Role of heat killed Mycobacterium w (Sepsivac) in coronavirus disease 2019 (COVID-19) Coronavirus disease 19 infection Mycobacterium w suspension alone, standard therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cadila Pharmaceuticals Ltd India 2020-09-15 CTRI/2020/09/027741 Phase Not Applicable Not yet recruiting 1 50 Dr Dharampal Singh Sudan 2020-09-14
Preventive Study among COVID 19 frontline warriors and their families Coronavirus disease 19 infection Variable regimens including Anu taila , Ayush Kwath , Chyavanprash , Samsamani vati Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) India 2020-09-15 CTRI/2020/09/027661 Phase Not Applicable Not yet recruiting 1 3000 Dr Krishna Rao S, Dr M MRao 2020-09-14
Testing efficacy of Homoeopathic Medicine Camphora 1000 C as an immune booster, reducing the incidence of coronavirus infection Coronavirus disease 19 infection Camphora 1000 C alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) India 2020-09-18 CTRI/2020/09/027688, MHC/CT/19-20/019 Phase 2/Phase 3 Clinical Not yet recruiting 1 4000 Dr Govindarajan Sankaran, Dr Meghna Shah, Dr Rajendra Shrimali 2020-09-14
SALIVA: Testing Saliva for SARS-CoV-2 Coronavirus disease 19 infection nasopharyngeal swabs alone, saliva/sputum testing alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Asian Healthcare Foundation India 2020-09-07 CTRI/2020/09/027597, SALIVA Phase Not Applicable Not yet recruiting 1 100 Dr D Nageshwar Reddy, Dr M Sasikala, Dr Sarala Kumari 2020-09-14
SH2020.COV01: Improving real-time COVID-19 monitoring through smartphone voice analysis Coronavirus disease 19 infection smartphone voice analysis alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Sonde Health India 2020-09-17 CTRI/2020/09/027691, SH2020.COV01, VocoQuest01 version 1.0 Phase Not Applicable Not yet recruiting 1 350 Dr Bharat Purandare, Dr Sharvari Rangnekar, Ms Ulka Gaikwad, Nutan Jadhav 2020-09-15
Satisfaction of medical students with online learning Coronavirus disease 19 infection online learning alone Newborn Infants (up to 5 months) Postgraduate Institute of Medical Education and Research India 2020-09-20 CTRI/2020/09/027719 Phase Not Applicable Not yet recruiting 1 500 Dr Nafisha Yasmin, Dr Saikat Kumar Dalui 2020-09-14
DeCOPO: Effect of Prone Positioning Combined With High Flow Oxygen Therapy on Oxygenation During Acute Respiratory Failure Due to COVID-19 Coronavirus disease 19 infection, Respiratory failure high flow oxygen therapy alone, prone positionning (PP) alone, supine position (SP) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital St. Joseph, Marseille, France 2020-09-30 2021-04-30 2020-04-03, DeCOPO, NCT04543760 Phase Not Applicable Not yet recruiting 0 7 Months 18 2020-09-15
COVID-2019 Testing and Vaccination Among African American and Latinx Public Housing Residents Coronavirus disease 19 infection increasing willingness and uptake of COVID-19 testing and vaccination alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), African Ancestry Charles Drew University of Medicine and Science US 2020-12-01 2022-11-30 COVID19TESTINGVACC, NCT04542395 Phase Not Applicable Not yet recruiting 1 24 Months 310 Mohsen Bazargan, PhD, Sharon Cobb, PhD 2020-09-14
COVID-19 Risk Reduction Among African American Parishioners Coronavirus disease 19 infection change in knowledge, motivation, skills, resources alone Healthy volunteers accepted, Aged Adults (65-79 yrs), Elderly Adults (80 and over) Charles Drew University of Medicine and Science US 2020-10-01 2021-09-30 COVID19CHURCH, NCT04542343 Phase Not Applicable Not yet recruiting 1 12 Months 265 Mohsen Bazargan, PhD, Sharon Cobb, PhD 2020-09-15
XPHI-COVID19: Moral Judgements and Choices of Caregivers in the Time of COVID-19 Pandemic Coronavirus disease 19 infection choices and judgements alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Caen University Hospital University of Geneva Switzerland 2020-09-03 2021-08-02 1474, NCT04542122, XPHI-COVID19 Phase Not Applicable Not yet recruiting 1 11 Months 500 Clement GAKUBA, MD PhD, Florian COVA, PhD 2020-09-14
COVID-19 in a Single Large UK Rheumatology Center and Impact on QOL Coronavirus disease 19 infection, Rheumatoid arthritis questionnaire alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The Royal Wolverhampton Hospitals NHS Trust UK 2020-10-31 2021-10-31 2020COV113, NCT04542031 Phase Not Applicable Not yet recruiting 1 12 Months 7911 James Bateman, Natasha Cleaton 2020-09-17
eWrite: Writing Activities and Emotions Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression positive psychology activities alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Pittsburgh US 2020-09-30 2021-08-01 NCT04539756, STUDY20060287, eWrite Phase Not Applicable Not yet recruiting 1 10 Months 250 Caitlin M DuPont, MS, Peter J Gianaros, PhD 2020-09-15
Mortality score development and costing studies among COVID patients Coronavirus disease 19 infection Seberang Jaya Hospital Malaysia 2020-11-29 2021-11-29 56362, NMRR-20-1918-56362 Phase Not Applicable Status not specified 1 12 Months DR. MONICA A/P DANIAL 2020-09-15
PLC: Managing a Dedicated Quarantine Center for COVID-19 Healthcare Workers of Putrajaya Hospital and their Satisfaction Rate Coronavirus disease 19 infection Putrajaya Hospital Malaysia 2020-09-14 2020-09-30 56376, NMRR-20-1936-56376, PLC Phase Not Applicable Status not specified 1 Dr MUHD SIV AZHAR MERICAN BIN ABDULLAH 2020-09-14
Satisfaction among VAS patients in HRPB Coronavirus disease 19 infection value-added services alone Hospital Raja Permaisuri Bainun Malaysia 2020-10-01 2021-03-31 56243, NMRR-20-1933-56243 Phase Not Applicable Status not specified 1 6 Months Chang Chee Tao, Miss Chew Lan Sim 2020-09-14
EpidHPj: Lessons Learnt From An Epidemiological Investigation Of COVID-19 Outbreak Amongst Healthcare Workers In A Major Specialist Hospital In Malaysia Coronavirus disease 19 infection Putrajaya Hospital Malaysia 2020-09-15 2020-09-30 55274, EpidHPj, NMRR-20-1935-55274 Phase Not Applicable Status not specified 1 Dr MUHD SIV AZHAR MERICAN BIN ABDULLAH 2020-09-15
An observational, case report study to determine the management of COVID-19 pneumonia in a kidney transplant recipient with the use of tocilizumab and hydroxychloroquine Coronavirus disease 19 infection, Pneumonia hydroxychloroquine plus tocilizumab University of Modena and Reggio Emilia Phase Not Applicable Status not specified 0 1 2020-09-14
Analysis of the Quality and Quantity of Antibiotic Prescriptions for Bacterial Respiratory Tract Superinfection in Patients Hospitalized in COVID-19 Wards Bacterial respiratory tract infection, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitair Ziekenhuis Brussel Belgium 2020-05-01 2021-03-01 2020-163, NCT04544072 Phase Not Applicable Recruiting 1 10 Months 400 Dora Mss Monteyne, nurse, Johan Dr Van Laethem, MD 2020-09-14
CoviTrem1: TREM-1 Pathway Activation in COVID-19 Coronavirus disease 19 infection blood sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Hospital, Nancy, France Inotrem SA, University Hospital, Limoges France 2020-10-01 2023-04-01 2020PI120, CoviTrem1, NCT04544891 Phase Not Applicable Not yet recruiting 2 30 Months 1000 Bruno Francois, Bruno Francois, MD, Gibot Sebastien 2020-09-14
Readiness Involvement Of Health Care Workers During Crisis Coronavirus disease 19 infection Sultanah Aminah Hospital Malaysia 2020-09-15 2021-02-15 55327, NMRR-20-1904-55327 Phase Not Applicable Status not specified 1 5 Months Puan Shirly Binti Berso 2020-09-15
MACBADCPPIHISM: Measuring anti-microbials consumption before and during Covid-19 pandemic period in hospitals in Selangor, Malaysia Coronavirus disease 19 infection Malaysia 2020-10-01 2022-10-01 56203, MACBADCPPIHISM, NMRR-20-1903-56203 Phase Not Applicable Status not specified 4 24 Months ABDULLAH FAIZ BIN ZAIHAN 2020-09-14
COVID19 and Olfactory Impairment Coronavirus disease 19 infection, Ear disease Universiti Kebangsaan Malaysia Malaysia 2020-09-07 2020-12-31 55310, NMRR-20-1901-55310 Phase Not Applicable Recruiting 1 3 Months DR SALINA BINTI HUSAIN 2020-09-14
Gastrointestinal Manifestations Among Patients With COVID-19 Coronavirus disease 19 infection, Gastrointestinal disease Assiut University Egypt 2020-06-01 2020-09-01 COVID19 AND GUT, NCT04544150 Phase Not Applicable Completed 1 3 Months 220 Ahmed Abu elfatth, Ahmed Mohammed Abu Elfatth 2020-09-14
Seroepidemiological investigation of SARS-CoV-2 infection in health workers working in COVID-19 centers Coronavirus disease 19 infection Seroepidemiological investigation alone Healthy volunteers accepted National Institute of Respiratory Diseases, Mexico Mexico 617/2020 Phase Not Applicable Recruiting 2 6568 Dr. Santiago Ávila 2020-09-14
IL-6 Gene (174G/C) Single Nucleotide Polymorphism as an Indicator of COVID-19 Severity in Egyptian Patients Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia ELISA technique alone, PCR-RFLP technique alone Tanta University Egypt 2020-09-15 2021-01-31 IL6 IN EGYPTIAN COVID PATIENTS, NCT04544033 Phase Not Applicable Recruiting 1 4 Months 120 bsant safwat kasem, master, bsant safwat kasem, principle investigator 2020-09-22
Observational Study of Convalescent Plasma for Treatment of Veterans With COVID-19 Coronavirus disease 19 infection COVID-19 convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) VA Office of Research and Development Mayo Clinic Foundation US 2020-08-07 2022-06-30 2030, CSP #2030, NCT04545047 Phase Not Applicable No longer recruiting 2 22 Months 4000 Nicholas L. Smith, PhD 2020-09-14
COVID-19 Risk From Attending Outpatient Appointments Coronavirus disease 19 infection Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Nottingham University Hospital University Hospital of Wales UK 2020-01-01 2021-01-01 20NS031, NCT04544176 Phase Not Applicable No longer recruiting 1 12 Months 34000 Nikos Evangelou, FRCP, DPhil (Oxon) 2020-09-15
Special Chinese Medicine Out-patient Program for Discharged COVID-19 Patients Coronavirus disease 19 infection, Lung disease, Spleen disease Variable regimens including American ginseng , Amomum villosum , Chenpi , Codonopsis , French Pinellia , Huoxiang , Licorice , Ophiopogonis , Poria , Schisandra , Stir-fried Atractylodes , Sunburn Astragalus , gypsum , light bamboo leaf , mulberry leaf , radix salviae , raw liquorice , reed root , salviae miltiorrhiza Hong Kong Baptist University Chinese University of Hong Kong, The University of Hong Kong Hong Kong 2020-09-07 2021-12-31 HA COVID-19, NCT04544605 Phase Not Applicable Recruiting 1 15 Months 150 Ching LIONG, PhD, Linda Zhong, PhD, Yi Bin FENG, PhD, ZhaoXiang Bian, Zhaoxiang Bian, PhD 2020-09-16
The efficacy and safety of ambroxol hydrochloride in the treatment of novel coronavirus pneumonia (COVID-19): a retrospective medical based study Coronavirus disease 19 infection ambroxol hydrochloride alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Zhangnan Hospital Boehringer Ingelheim International GmbH China 2020-05-01 2022-05-31 ChiCTR2000038160 Phase 2 Clinical Recruiting 1 25 Months 1200 Hong Cheng, Kun Yang 2020-09-14
CLOVIS: Pediatric Intensive Care and COVID-19 Coronavirus disease 19 infection, Lung embolism, Respiratory distress syndrome, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopital de Bicetre France 2020-03-26 2021-06-01 CLOVIS, NCT04544878, PS-PICRN--20001 Phase Not Applicable Recruiting 1 14 Months 100 Clemence Marais, MD, MSc, Jordi Miatello, MD, MSc, Pierre Tissieres, MD, DSc 2020-09-14
A Phase I Clinical Trial of Influenza virus Vector COVID-19 Vaccine for intranasal Spray (DelNS1-2019-nCoV-RBD-OPT1) Coronavirus disease 19 infection DelNS1-2019-nCoV-RBD-OPT1 alone, Influenza virus Vector COVID-19 Vaccine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Jiangsu Province Centers for Disease Control and Prevention Beijing Wantai Biological Pharmacy Enterprise Co Ltd China 2020-09-01 2021-10-01 ChiCTR2000037782, DelNS1-2019-nCoV-RBD-OPT1 Phase 1 Clinical Not yet recruiting 1 13 Months 60 Fengcai Zhu, Xiangzhong Ye 2020-09-15
A phase I/II clinical study to asses virus-like particle (VLP) vaccine in the treatment of subjects with COVID-19 infection Coronavirus disease 19 infection SARS-CoV-2 vaccine (virus like particle-based vaccine, SpyCatcher/SpyTag, COVID-19), SpyBiotech/Serum Institute of India alone COVID19 Spike glycoprotein modulator Serum Institute of India Ltd SpyBiotech Limited Australia Phase 1/Phase 2 Clinical Recruiting 1 2020-09-23
Trial of Famotidine and N-Acetyl Cysteine for Outpatients With COVID-19 Coronavirus disease 19 infection N-acetyl cysteine alone, N-acetyl cysteine plus famotidine Histamine H2 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Prisma Health-Upstate Clemson University 2020-09-30 2021-08-31 NCT04545008, PRO00100394 Phase 1 Clinical Not yet recruiting 0 11 Months 42 John J O'Connell, M.D., Julie Martin, DNP 2020-09-14
A phase II/III study to evaluate RHB-107 in an outpatient setting in patients with COVID-19 Coronavirus disease 19 infection upamostat alone Serine protease inhibitor, Trypsin 1 inhibitor, Trypsin 2 inhibitor, Trypsin 3 inhibitor, Urokinase plasminogen activator inhibitor RedHill Biopharma Ltd US Phase 2/Phase 3 Clinical Planned 1 2020-09-11
A retrospective, cohort study to evaluate whether ibuprofen administration to patients with COVID-19 was associated with worse clinical outcomes, compared with paracetamol or no antipyretic Coronavirus disease 19 infection ibuprofen alone, paracetamol alone Israel Phase Not Applicable Status not specified 1 403 2020-09-14
DEXA-REFINE: Efficacy of Dexamethasone in Patients With Acute Hypoxemic Respiratory Failure Caused by Infections Adult respiratory distress syndrome, Coronavirus disease 19 infection, Hypoxia, Respiratory failure, Viral pneumonia dexamethasone alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dr. Negrin University Hospital Centro de Investigación Biomédica en Red, Li Ka Shing Knowledge Institute Spain 2020-10-07 2023-12-30 DEXA-REFINE, ICI20-00062, NCT04545242 Phase 4 Clinical Not yet recruiting 39 38 Months 980 Alberto Martínez-Ruiz, MD, Alec Tallet, MD, Alfonso Ambrós, MD, Angel Candela, MD, Anxela Vidal, MD, Arthur Slutsky, MD, Carlos Ferrando, MD, Carlos García-Palenciano, MD, Carmen Martin-Delgado, MD, Carmen Martín, MD, Chanel Martínez, MD, Concepción Tarancón, MD, César Aldecoa, MD, César Calvo, MD, Dacil Parrilla, MD, David Pestaña, MD, Demetrio Carriedo, MD, Domingo Martínez, MD, Elena González, MD, Eleuterio Merayo, MD, Emilio Maseda, MD, Federico Gordo, MD, Fernando Mosteiro, MD, Fernando Suarez-Sipmann, MD, Francisco Alba, MD, Francisco J Díaz, MD, Gerardo Aguilar, MD, Gonzalo Tamayo, MD, Isabel Murcia, MD, Isidro Prieto, MD, Javier Fernández, MD, Jesús Rico, MD, Jesús Villar, MD, Josep Trenado, MD, José A Carbonell, MD, José A Lorente, MD, José Ferreres, MD, José I Gómez-Herreras, MD, José M Añón, MD, Juan A Soler, MD, Juan C Figueira, MD, Juan M Mora-Ordoñez, MD, Julián Álvarez, MD, Lidia Pita-García, MD, Lorena Fernández, MD, Manuel Castallá, Marina Varela, MD, Mario Chico, MD, Mario Lorenzo-López, MD, María Hernández, MD, María L Blasco, MD, María M Fernández, MD, Miguel A Romera, MD, Pablo Blanco-Schweizer, MD, Pablo Monedero, MD, Pablo Serna-Grande, MD, Paloma González-Arenas, MD, Pedro Castro, MD, Piedad Martinez-Gil, MD, Pilar Diaz-Parada, MD, Raquel Herrero, MD, Raquel Montiel, MD, Ricard Mellado-Artigas, MD, Rosario Solano, MD, Ruth Corpas, MD, Silvia Cortés-Díaz, MD, Tomás Muñoz, MD, Trinidad Puente, MD, Ángela Prado-Mira, MD 2020-09-18
A phase IIb/III clinical trial of protein subunit vaccine (molecular clamp, COVID-19), University of Queensland for the potential prevention of COVID-19 infection Coronavirus disease 19 infection protein subunit vaccine (molecular clamp, COVID-19), University of Queensland alone COVID19 Spike glycoprotein modulator CSL Ltd 2020-12-31 Phase 2/Phase 3 Clinical Planned 0 2020-09-11
Observational, Open Study of Polyoxidonium in Hospitalized Patients With COVID-19 Coronavirus disease 19 infection, Tachypnea Polyoxidonium alone, complex treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) NPO Petrovax Pharm LLC Russian Federation 2020-04-09 2020-10-31 COVID_V_1.0, NCT04542226 Phase Not Applicable No longer recruiting 1 6 Months 81 2020-09-15
Reszinate: Can SARS-CoV-2 Viral Load and COVID-19 Disease Severity be Reduced by Resveratrol-assisted Zinc Therapy Coronavirus disease 19 infection Zinc Picolinate plus resveratrol Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Swedish Medical Center (Seattle) US 2020-09-30 2022-06-30 NCT04542993, Reszinate, SHS KAPH NSWE 20090 Phase 2 Clinical Not yet recruiting 1 21 Months 60 Cancer Regulatory, Cancer Research, Chris Nunn, MD 2020-09-14
Efficacy of mouth-rinses in reducing SARS CoV-2 viral load in the saliva of COVID-19 positive patients Coronavirus disease 19 infection cetylpyridinium chloride alone, chlorhexidine gluconate alone, povidone-iodine alone National Dental Centre Singapore Singapore 2020-04-15 2021-06-16 329/2020, ISRCTN95933274 Phase 2 Clinical Recruiting 1 14 Months 68 Dr Jaya Seneviratne 2020-09-15
Using BCG to Protect Senior Citizens During the COVID-19 Pandemic Coronavirus disease 19 infection BCG vaccine alone Healthy volunteers accepted, Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bandim Health Project Odense Municipality, Odense Patient Explorative data Network (OPEN), Odense Patient data Explorative Network, Odense University Hospital Guinea-Bissau 2020-09-11 2022-03-31 BCG-DENMARK-SENIOR, NCT04542330 Phase 3 Clinical Not yet recruiting 1 18 Months 1900 Anne Marie Rosendahl Madsen, MD, Christine Stabell Benn, DMSc 2020-09-14
Qualitative Evaluation of Tear Fluid and Blood for Auto Antibodies Produced in Response to COVID-19 Coronavirus disease 19 infection ELISA assay alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) 2020-09-15 2020-12-31 CVDTRS001, NCT04542980 Phase Not Applicable Not yet recruiting 0 3 Months 200 Anna Daily, PhD 2020-09-14
OMC-KTR: Optimized Management of Covid-19 Positive Kidney Transplant Recipients: Single-Center Experience From the Middle East Coronavirus disease 19 infection, Kidney transplantation Ministry of Health in Kuwait Kuwait 2020-03-01 2020-08-31 2020/1481, NCT04542954, OMC-KTR Phase Not Applicable Completed 1 6 Months 104 2020-09-12
NINTECOR: Nintedanib for the Treatment of SARS-Cov-2 Induced Pulmonary Fibrosis Coronavirus disease 19 infection, Pulmonary fibrosis nintedanib alone CSF-1 antagonist, FGF receptor antagonist, FGF1 receptor antagonist, FGF2 receptor antagonist, FGF3 receptor antagonist, Flt3 tyrosine kinase inhibitor, Lck tyrosine kinase inhibitor, Lyn tyrosine kinase inhibitor, PDGF receptor alpha antagonist, PDGF receptor antagonist, PDGF receptor beta antagonist, Src tyrosine kinase inhibitor, VEGF receptor antagonist, VEGF-1 receptor antagonist, VEGF-2 receptor antagonist, VEGF-3 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris Boehringer Ingelheim International GmbH 2020-09-30 2021-12-31 APHP200527, NCT04541680, NINTECOR Phase 3 Clinical Not yet recruiting 0 15 Months 250 Bruno Crestani, MD,PHD 2020-09-21