Last updated: Oct 22, 2020 - 02:00 BST

Title Indication Intervention Actions PatientSelection Sponsor Collaborator Country StartDate EndDate Identifiers Phase Recruitment Status Sites Trial Duration Enrollment Count Contacts LastChanged
Ampligen in Chronic Fatigue Syndrome Chronic fatigue syndrome, Coronavirus disease 19 infection rintatolimod alone 2,5-Oligoadenylate synthetase stimulator, Interferon type I receptor agonist, Ribonuclease stimulator, TLR-3 agonist Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) AIM ImmunoTech Inc US AMP 511, NCT00215813 Phase 3 Clinical Recruiting 2 Ann Marie Coverly, Charles Lapp, MD, Charles W. Lapp, M.D., Daniel Peterson, M.D., Daniel Peterson, MD, Diane Young 2020-10-15
Expressive Writing for COVID-19 Resilience Acute stress disorder, Coronavirus disease 19 infection, Depression virtually-delivered expressive writing alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Duke University US 2020-05-26 2020-08-17 NCT04589104, PRO00105575 Phase Not Applicable Completed 0 2 Months 63 Oliver Glass, PhD 2020-10-21
Supporting Family Members With Severe Grief Reaction During the COVID-19 Pandemic Coronavirus disease 19 infection, Psychiatric disorder Bereavement Virtual Support alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ottawa Hospital Research Institute Canada 2020-11-01 2022-01-01 20200653-01H, NCT04588415 Phase Not Applicable Not yet recruiting 0 14 Months 200 Antoine Przybylak-Brouillard, Peter Lawlor 2020-10-21
COVID-19-DM: The Effect of COVID-19 on Diabetes Mellitus Coronavirus disease 19 infection, Diabetes mellitus Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Usak University, Turkey Turkey 2020-03-20 2020-11-01 COVID-19-DM, NCT04592055, UU-DM002 Phase Not Applicable Recruiting 0 7 Months 500 Cevdet Duran, Cevdet Duran, Prof 2020-10-21
ACTIV-1 IM: Immune Modulators for Treating COVID-19 Coronavirus disease 19 infection Variable regimens including abatacept , cenicriviroc , infliximab , remdesivir CCR2 chemokine antagonist, CCR5 chemokine antagonist, COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, Cytotoxic T-lymphocyte protein-4 stimulator, RNA polymerase modulator, T cell surface glycoprotein CD28 inhibitor, TNF alpha ligand inhibitor, TNF binding agent Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Duke University Biomedical Advanced Research and Development Authority (BARDA), National Center For Advancing Translational Sciences US 2020-10-31 2021-09-30 ACTIV-1 IM, NCT04593940, PRO00106301 Phase 2 Clinical Not yet recruiting 0 11 Months 2190 Daniel K Benjamin, MD, PhD, Lori Hudson, PhD, Theresa Jasion, MS 2020-10-21
A phase II clinical study to assess Nylexa in the treatment of patients with COVID-19 Coronavirus disease 19 infection mercaptamine (parenteral, COVID-19), NovaBiotics alone NovaBiotics Ltd Technology Strategy Board Phase 2 Clinical Planned 0 2020-10-21
FaST-1: Furosemide as Supportive Therapy for COVID-19 Respiratory Failure Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia nebulized furosemide alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Queen's University University Health Network Toronto Canada 2020-10-19 2021-10-01 FAST-1, FaST-1, NCT04588792 Phase 2/Phase 3 Clinical Not yet recruiting 4 11 Months 640 Dave Maslove, MD, Gordon Boyd, MD, HT Wand, MD, John Muscedere, MD, Oleksa Rewa, MD, Osama Loubani, MD, Stephanie Sibley, MD, Tracy Boyd 2020-10-21
Mindfulness to Mitigate Psychological Threat and Improve Engagement and Learning in Introductory Physics Courses Coronavirus disease 19 infection, Psychiatric disorder Mindfulness Training alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Pittsburgh James S McDonnell Foundation, National Science Foundation US 2020-10-12 2022-12-31 NCT04589377, STUDY19050258 Phase Not Applicable Recruiting 1 26 Months 150 Brian Galla, PhD, Sara Jahanian, BS, Timothy Nokes-Malach, PhD 2020-10-21
The Peer-Delivered "Mind. Body. Voice." Program for High School Women (Mbv) - Remote Coronavirus disease 19 infection, Eating disorder mind, body, voice program alone Healthy volunteers accepted, Female University of Colorado US 2020-10-09 2031-05-31 18-0007-03, NCT04591912 Phase Not Applicable Recruiting 1 127 Months 140 Bernadette Park, PhD, Gavin Bell, BA, Leah Pena Teeters, PhD, Leah Teeters, PhD, Sona A Dimidjian, PhD, Sona Dimidjian 2020-10-21
COCO-LATE: Late Clinical Events Associated With COVID-19 Infection Coronavirus disease 19 infection Biocollection alone, Follow-up visit alone, Questionnaire alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier de Tourcoing French Guiana, France 2020-10-31 2022-08-31 COCO-LATE, NCT04591613, RIPH_2020_09 Phase Not Applicable Not yet recruiting 17 22 Months 1000 Clara FLATEAU, Cédric JOSEPH, David CHIRIO, Delphine POITRENAUD, Dominique SALMON, Elisabeth BOTELHO-NEVERS, François GOEHRINGER, Louis BERNARD, Marie GOUSSEFF, Marie PICHENOT, Nicolas VIGNIER, Olivier ROBINEAU, Olivier ROBINEAU, MD PhD, Reda CHIKOUCHE, Solange TREHOUX, PhD, Sophie PANAGET, Vincent DUBEE, Xavier LESCURE 2020-10-21
Dulce Digital-COVID Aware (DD-CA) Discharge Texting Platform for US/Mexico Border Hispanics With Diabetes + COVID-19 Coronavirus disease 19 infection, Non-insulin dependent diabetes Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Scripps Whittier Diabetes Institute National Institute of Diabetes, Digestive and Kidney Diseases US 2020-11-01 2021-08-31 3R01DK112322-05S1, 3R01DK112322-05S1, NCT04591015 Phase 3 Clinical Not yet recruiting 1 10 Months 172 Athena Philis-Tsimikas, MD 2020-10-21
COVID-19-PE: Pulmonary Embolism and COVID-19 Coronavirus disease 19 infection, Lung embolism Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Usak University, Turkey Turkey 2020-03-01 2020-12-01 COVID-19-PE, NCT04590378, UU-PE001 Phase Not Applicable Recruiting 1 9 Months 600 Barış Sevinç, M.D., Canan Akkus, M.D., Cevdet Duran, M.D., Cevdet Duran, Prof., Hakan Yilmaz, M.D. 2020-10-21
COVID-RASi: The COVID-RASi Trial (COVID-19) Cardiovascular disease, Coronavirus disease 19 infection Angiotensin II Receptor Blockers alone, Angiotensin converting enzyme inhibitor alone, renin-angiotensin system inhibitors alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ottawa Heart Institute Research Corp Canada 2020-10-30 2022-08-31 COVID-RASi, CTO-3212, NCT04591210 Phase 3 Clinical Not yet recruiting 1 22 Months 1155 Ermina Moga, Peter Liu, MD 2020-10-21
COVID-19 and Lung Ultrasound Utility Coronavirus disease 19 infection Butterfly iQ system alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Canada 2020-09-15 2021-09-30 0001, NCT04591158 Phase Not Applicable Recruiting 1 12 Months 100 William Cherniak, MD, MPH 2020-10-21
Maternal Telemental Health Interventions in Response to Covid-19*(CoronaVirus) Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression, Phobia Low-Intensity Psychosocial Interventions through Telemental health alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Hamad Medical Corp Qatar 2020-11-30 2022-02-28 MRC-05-087, NCT04594525 Phase Not Applicable Not yet recruiting 1 15 Months 58 2020-10-21
COVID-19 Burnout Study Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection Mindfulness Based Intervention alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Health Network Toronto 2020-11-01 2021-07-01 20-5678, NCT04594278 Phase Not Applicable Not yet recruiting 0 8 Months 100 2020-10-21
GLS-1027 for the Prevention of Severe Pneumonitis Caused by SARS-CoV-2 Infection Coronavirus disease 19 infection, Viral pneumonia GLS-1027 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) GeneOne Life Science Inc 2020-11-30 2021-11-30 GLS27-005, NCT04590547 Phase 2 Clinical Not yet recruiting 0 12 Months 132 Medical Monitor, Project Manager 2020-10-21
PRISM: COVID-19: Pediatric Research Immune Network on SARS-CoV-2 and MIS-C Coronavirus disease 19 infection, Inflammatory disease Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) National Institute of Allergy and Infectious Diseases Autoimmunity Centers of Excellence US 2020-10-31 2022-04-30 DAIT PRISM-01, NCT04588363, NIAID CRMS ID#: 38772, PRISM Phase Not Applicable Not yet recruiting 21 18 Months 250 Charles E. Canter, MD, Ekemini Akan Ogbu, MBBS, MSc, Emily Wasserman, MD, MS, Hayley Gans, MD, James B. Schneider, MD, James D. Wilkinson, MD, MPH, Joseph Rossano, MD,MS,FAAP,FACC, Karen P. Acker, MD, Lara A. Danziger-Isakov, MD, MPH, Leigh M. Howard, MD, MPH, Lisa F. Imundo, MD, Maria T. Thanjan, MD, Marian G. Michaels,, MD, MPH, Moshe Arditi, MD, Nadine F. Choueiter, MD, Natasha B Halasa, MD, MPH, Natasha Ruth, MD, MS, Octavio Ramilo, MD, Paul F. Kantor, MBBCh,MSc,FRCPC, Pramod Narula, MD, Rakesh Singh, MD, Rana Chakraborty, MD, DPhil, Steven A. Webber, MBChB, MRCP, William T. Mahle, MD 2020-10-21
This is a Phase I Clinical Trial to Evaluate the Safety, Pharmacokinetics, and Immunogenicity of ADM-03820, a Monoclonal Antibody Cocktail Being Tested for the Treatment and Prevention of COVID-19 Coronavirus disease 19 infection SARS-CoV-2 monoclonal antibodies (COVID-19), Ology/ VUMC alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Ology Bioservices Inc US 2020-11-16 2021-08-30 ADM03820-001, NCT04592549 Phase 1 Clinical Not yet recruiting 0 9 Months 40 Angie Kimbler, Cassandra C Key, MD, Jonathan P Wilson, DO 2020-10-21
Study to Evaluate the Safety, Tolerability and Immunogenicity of an RNA Vaccine Candidate Against COVID-19 in Healthy Japanese Adults Coronavirus disease 19 infection BNT-162b2 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Japanese Ancestry BioNTech SE Pfizer Inc Japan 2020-10-21 2021-11-30 C4591005, NCT04588480 Phase 1/Phase 2 Clinical Not yet recruiting 2 13 Months 160 Pfizer CT.gov Call Center 2020-10-21
To Evaluate the Safety, Tolerability and Pharmacokinetic Properties of DWRX-2003 Coronavirus disease 19 infection repositioned niclosamide (refractory lung disease/COVID-19), Daewoong Pharmaceutical/Institut Pasteur Korea alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Daewoong Pharmaceutical Co Ltd Novotech (Australia) Pty Ltd 2020-10-19 2021-06-30 DW_DWJ1516101_AUSTRALIA, NCT04592835 Phase 1 Clinical Not yet recruiting 0 8 Months 24 2020-10-21
Effectiveness of Ivermectin and Doxycycline on COVID-19 Patients Coronavirus disease 19 infection Mechanical ventilation alone, Oxygen therapy/ C-Pap alone, Variable regimens including Vitamin C , Vitamin D3 , Zinc , acetaminophen , azithromycin , dexamethasone , doxycycline (Doxycin) , ivermectin , methylprednisolone Chloride channel modulator Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Alkarkh Health Directorate-Baghdad Iraq 2020-07-01 2020-10-14 IVM-DOX, NCT04591600 Phase 1/Phase 2 Clinical Completed 1 3 Months 140 Ahmed Sahib Abdulamir 2020-10-20
Study of Multiple Candidate Agents for the Treatment of COVID-19 in Hospitalized Patients Coronavirus disease 19 infection Standard of care alone, apremilast alone PDE 4 inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Amgen Inc 2020-10-26 2021-07-13 2020-002594-10, COV-01, NCT04590586 Phase 3 Clinical Not yet recruiting 0 8 Months 700 Amgen Call Center 2020-10-20
Seroprevalence of SARS CoV-2 infections/Covid-19 in blood donors and patients of the University Hospitals in Leipzig Coronavirus disease 19 infection Institut für Virologie, Universitätsklinikum Leipzig Germany 2020-06-20 147/20-ek, DRKS00023364 Phase Not Applicable Recruiting 1 2000 Christian Jassoy 2020-10-20
Evaluation the effect of virtual pulmonary rehabilitaion on covid 19 patients Coronavirus disease 19 infection Breathing exercise alone, Virtual pulmonary rehabilitation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Shiraz University of Medical Sciences Iran 2020-10-20 IR.SUMS.MED.REC.1399.364, IRCT20200930048892N1 Phase Not Applicable Recruiting 3 70 Abbas Rezaeian zade, Fariba Erfani, Parnian Nikmanesh, Seyed Mohammad Kazem Tadayyon, Seyed Rouhollah Mousavi 2020-10-20
Abdominal CT scan findings in patients with COVID-19 Coronavirus disease 19 infection abdominal CT scan alone Philippine General Hospital Philippines 2020-08-15 2020-09-18 PHRR201015-003026 PHRR201015-003026 Phase Not Applicable Completed 1 1 Month Gerard Eastdon Truadio D. Ochoco, MD 2020-10-20
SPARCOL: SuPAR in Adult Patients With COVID-19 Coronavirus disease 19 infection ELISA assay alone, suPARnostic kit (ViroGates) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Thessaly Greece 2020-10-16 2020-12-10 NCT04590794, SPARCOL, UTHDA-AC03 Phase Not Applicable Not yet recruiting 1 1 Month 500 Athanasios Chalkias, PhD, Barbara Boutsis, Mrs, Eleni Laou, PhD 2020-10-21
CoV-Early: Early Convalescent Plasma Therapy for High-risk Patients With COVID-19 in Primary Care Coronavirus disease 19 infection convalescent plasma alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Erasmus University Medical Center Rotterdam Leiden University Medical Center, Sanquin Plasma Products B.V., The Netherlands Organisation for Health Research and Development Netherlands 2020-10-12 2023-11-01 CoV-Early, NCT04589949, NL74972.078.20 Phase 3 Clinical Recruiting 11 36 Months 690 Arvind Gharbharan, MD, Bart Rijnders, MD, PhD, Carlijn Jordans, MD, Casper Rokx, MD, PhD, D. Postma, MD, PhD, E. Jong, MD, PhD, Elana van Leeuwen, MD, PhD, Faiz Karim, MD, PhD, I Ludwig, MD, JJ Zwaginga, MD/PhD, L. Kampschreur, MD, PhD, R.W. van Etten, MD, PhD, Robert-Jan Hassing, MD, PhD, Robin Soetekouw, MD 2020-10-20
Development of a risk prediction model for people with diabetes and COVID-19 in Scotland Coronavirus disease 19 infection, Diabetes mellitus risk prediction model alone UK 2020-04-06 2020-07-31 ISRCTN45562523, PBPP REF. 1617- 0147 Phase Not Applicable Completed 1 3 Months 5782649 Prof Colhoun 2020-10-20
COVID-19-DM2: The Effect of Diabetes Mellitus on the Prognosis of Patients With COVID-19 Coronavirus disease 19 infection, Diabetes mellitus Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Usak University, Turkey Turkey 2020-03-20 2020-11-01 COVID-19-DM2, NCT04591704, UU-DM003 Phase Not Applicable Recruiting 1 7 Months 2000 Cevdet Duran 2020-10-21
Evaluation of the effect of Tofacitinib in COVID-19 patients Coronavirus disease 19 infection Rhofanib (Alvand Nanotechnology Company) alone Iran University of Medical Sciences Iran 2020-08-21 IR.IUMS.FMD.REC.1399.329, IRCT20200531047619N1 Phase 3 Clinical Recruiting 1 10 Seyed Abbas Motavalian, Simin Almasi 2020-10-21
ICE-COVID: Iota-carrageenan Nasal Spray COVID-19 Prophylaxis for Healthcare Professionals Coronavirus disease 19 infection Coldamaris plus iota-carrageenan (intranasal, H1N1 influenza), Marinomed Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Swansea University, Wales Abertawe Bro Morgannwg University Health Board, Cardiff University, Marinomed Biotechnologie GmbH, Walgreens Boots Alliance Inc UK 2020-12-20 2021-12-01 283187, ICE-COVID, NCT04590365 Phase 3 Clinical Not yet recruiting 1 11 Months 480 Iain S Whitaker, PhD FRCS, Zita M Jessop, MBBChir PhD 2020-10-21
FLAVOCOV Distributed Clinical Trial- COVID-19 Coronavirus disease 19 infection flavonoids alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kenya Medical Research Institute Kenya 2020-11-01 2021-01-31 PACTR202010537777617 Phase Not Applicable Not yet recruiting 1 3 Months 200 Leah Kigondu, Rick Sheridan, Willie Nyambati 2020-10-21
COREADOM: French Cohort of COVID-19 Patients With Post-intensive Care Syndrome Coronavirus disease 19 infection Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-10-15 2021-09-15 APHP200812, COREADOM, NCT04590170 Phase Not Applicable Not yet recruiting 1 11 Months 50 Camille : Camille, MD, Camille Camille, MD, Marie Benhammani-Godard, Marie-Martine Marie-Martine, MD, PhD 2020-10-21
VISION-Acute: The VISION-Acute Study Coronavirus disease 19 infection, Hypertension, Hypotension, Hypoxia, Respiratory disease Lifelight data collect app (Xim Ltd) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Xim Ltd Portsmouth Hospitals UK 2020-10-31 2021-01-31 NCT04589923, PHT/2020/50, VISION-Acute Phase Not Applicable Not yet recruiting 1 3 Months 200 Laura Wiffen 2020-10-20
Allocetra-OTS in COVID-19, Phase II Coronavirus disease 19 infection, Multiple organ failure, Respiratory disease, Respiratory failure, Septic shock Allocetra plus Ringer's lactate solution Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hadassah Medical Organization Barzilai medical center, Tel Aviv Sourasky Medical Center Israel 2020-10-18 2021-03-31 DM004, NCT04590053 Phase 2 Clinical Recruiting 3 5 Months 24 Dror Mevorach, MD, Peter V van Heerden, MD, Ronen Ben-Ami, Prof., Shlomo L Maayan, Prof. 2020-10-21
Levamizole in treatment of COVID-19 Coronavirus disease 19 infection levamisole alone, standard therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Isfahan University of medical Sciences Iran 2020-10-22 IR.MUI.MED.REC.1399.246, IRCT20181208041886N1 Phase 2 Clinical Not yet recruiting 1 60 Dr. Shaghayegh Haghjoo, Morteza Pourahmad 2020-10-21
COVID-19 biomarker: Identification of biomarkers for prognosis of morbidity and mortality of SARS-CoV-2 (COVID-19) patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Munster Germany 2020-04-09 AZ 2020-210-f-S, COVID-19 biomarker, DRKS00023322 Phase Not Applicable Recruiting 1 100 Phil-Robin Tepasse 2020-10-21
A Clinical Trial of a Plasmid DNA Vaccine for COVID-19 (Covigenix VAX-001) in Adults Coronavirus disease 19 infection SARS-CoV-2 DNA vaccine (COVID-19), Entos/ Epivax alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Entos Pharmaceuticals Inc Canadian Institutes of Health Research Canada 2020-11-30 2021-06-30 ENTVAX01-101, NCT04591184 Phase 1 Clinical Not yet recruiting 1 7 Months 72 Gregory Reid, M.Sc, MBA, Sally Jones, Scott A. Halperin, M.D. 2020-10-21
Anhydrous Enol-Oxaloacetate (AEO) on Improving Fatigue in Post-COVID-19 Survivors Coronavirus disease 19 infection, Fatigue anhydrous enol-oxaloacetate (Terra Biological LLC) alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Terra Biological LLC US 2020-10-15 2021-06-15 NCT04592354, TB-AEO-2020 POST COVID FATIGUE Phase Not Applicable Recruiting 1 8 Months 40 Alan B Cash, MS, Lisa Tully, Ph.D. 2020-10-21
A prospective study to evaluate the accuracy of the Cue COVID-19 Test in patients Coronavirus disease 19 infection Cue COVID-19 Test alone Mayo Clinic Foundation Phase Not Applicable Status not specified 0 2020-10-20
A phase I/II clinical study to assess MRT-5500 in the treatment of subjects with SARS-CoV-2 infection Coronavirus disease 19 infection SARS-CoV-2 mRNA vaccine (COVID-19), Sanofi Pasteur/ Translate Bio alone Sanofi SA 2020-12-31 Phase 1/Phase 2 Clinical Planned 0 2020-10-20
A clinical trial to evaluate the efficacy of erdosteine in the treatment of hospitalized patients with COVID-19 infection with severe respiratory failure Coronavirus disease 19 infection, Respiratory failure erdosteine alone Elastase inhibitor Recipharm AB Italy Phase 2 Clinical Status not specified 1 20 2020-10-20
AERATOR: Studying aerosol emission of the COVID-19 virus in healthcare settings Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) North Bristol NHS Trust National Institute for Health Research (NIHR), United Kingdom Research & Innovation UK 2020-09-19 2021-09-19 3.4, IRAS 288784, CPMS 47097, AERATOR, ISRCTN21447815 Phase Not Applicable Recruiting 2 12 Months 600 Dr Fergus Hamilton 2020-10-20
Experience In Managing Special Groups Of Person Under Surveillance In Kelantan Coronavirus disease 19 infection Ministry of Health, Malaysia Malaysia 2020-10-18 2021-10-05 56079, NMRR-20-2238-56079 Phase Not Applicable Status not specified 1 11 Months Dr Farah Munirah Binti Mior Mazlan, dr NIK AIDA BT NIK ADIB 2020-10-20
Treatment of Covid-19 Using Infrared and/or Vitamin C Coronavirus disease 19 infection Infrared sauna therapy alone, vitamin C alone Healthy volunteers accepted GAAD Medical Research Institute Inc Canada 2020-10-30 2021-07-10 GAADMRI, NCT04584437 Phase Not Applicable Not yet recruiting 1 8 Months 400 Dr. Kwasi D Donyina, PhD, Yaa A Donyina, MDE 2020-10-20
A multicenter, clinical trial to validate the effectiveness of the Monocyte Distribution Width (MDW) hematology biomarker in the rapid detection of Multisystem Inflammatory Syndrome in Children (MIS-C) following SARS-CoV-2 infection Coronavirus disease 19 infection, Inflammatory disease Beckman Coulter Diagnostics Biomedical Advanced Research and Development Authority (BARDA), Johns Hopkins University School of Medicine, Massachusetts General Hospital, University of Florida US Phase Not Applicable Planned 3 Lael Yonker, M.D 2020-10-20
Secondary attack rate of COVID-19 and risk factors for transmission Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sri Ramachandra Institute of Higher Education and Research India 2020-10-16 CTRI/2020/10/028439 Phase Not Applicable Not yet recruiting 1 100 Manisha Arthur 2020-10-20
Efficacy of daclatasvir + sofosbuvir in patients with severe acute respiratory syndrome coronavirus (SARS-COVID-19) Coronavirus disease 19 infection, Viral pneumonia daclatasvir/sofosbuvir (Danesh Pharmaceutical Development Company) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ahvaz University of Medical Sciences Ahvaz Jundishapur University of Medical Sciences Iran 2020-06-25 IR.AJUMS.REC.1399.300, IRCT20200816048422N1 Phase 1/Phase 2 Clinical No longer recruiting 1 70 Dr Fatemeh Ahmadi, Dr. Fatemeh Ahmadi, Dr. Mohammad Badawi, Dr. Zahra Fakhraei 2020-10-20
PRECISION: An observational PRECISION study , to examine the immune responses to COVID-19 in healthy volunteers who have recovered from COVID-19 or were asymptomatic Coronavirus disease 19 infection Columbia University, Tonix Pharmaceuticals Holding Corp US PRECISION, TNX-C002 Phase Not Applicable Recruiting 1 Dr. Ilya Trakht, Dr. Sergei Rudchenko, Ph.D 2020-10-19
Effect of Ayurvedic Treatment Regimen in COVID-19 Patients Coronavirus disease 19 infection Variable regimens including Bilwadi Yog , Kantakaryavaleha , Shadangodak Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ministry of Ayush India 2020-11-02 CTRI/2020/10/028437 Phase 3 Clinical Not yet recruiting 3 380 Dr Leena Badgujar, Dr Milind B Nikumbh, Dr Shoeb Shaikh 2020-10-21
A trial to evaluate FX-06 in severe cases of COVID-19 Coronavirus disease 19 infection FX-06 alone Cadherin-5 modulator, Factor Ia modulator F4 Pharma GmbH Europe Phase Not Applicable Planned 0 2020-10-19
Perspective of cancer patient in COVID-19 pandemic Cancer, Coronavirus disease 19 infection chemotherapy alone, radiotherapy alone, systemic therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Indira Gandhi Medical College India 2020-12-01 CTRI/2020/10/028438 Phase 3 Clinical Not yet recruiting 1 1000 Shabnum Thakur 2020-10-21
A trial to evaluate stem cell therapy as a treatment for acute symptoms of COVID-19 Coronavirus disease 19 infection stem cell therapy alone BioXcellerator US Phase Not Applicable Not yet recruiting 1 2020-10-19
This study is designed to look at certain blood parameters like biomarkers for predicting the outcome of COVID patients Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) St Johns Medical College India 2020-10-25 CTRI/2020/10/028436 Phase Not Applicable Not yet recruiting 1 130 Dr Amarja Havaldar 2020-10-20
A phase III trial to evaluate post-exposure prophylaxis and pre-emptive treatment of AZD-7442 in covid-19 patients Coronavirus disease 19 infection AZD-7442 alone COVID19 Spike glycoprotein inhibitor AstraZeneca plc Phase 3 Clinical Planned 0 1100 2020-10-20
A phase III trial to evaluate the safety and efficacy of AZD7442 to prevention of COVID-19 Coronavirus disease 19 infection AZD-7442 alone COVID19 Spike glycoprotein inhibitor AstraZeneca plc Phase 3 Clinical Planned 0 5000 2020-10-20
Mental health of COVID 19 patients during outbreak Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression RTPCR test  alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) All India Institute of Ayurveda India 2020-10-16 CTRI/2020/10/028432 Phase Not Applicable Not yet recruiting 1 400 Dr Shivakumar Harti 2020-10-20
CoMMinS: COVID-19 testing and infection control in schools Coronavirus disease 19 infection RNA PCR test alone, Saliva-based antibody test alone, Viral RNA genome sequencing alone University of Bristol Medical Research Council UK 2020-09-01 2021-08-31 CoMMinS, IRAS 290071, ISRCTN82901740 Phase Not Applicable Not yet recruiting 1 12 Months 5000 Prof Caroline Relton 2020-10-20
A phase III clinical trial of Sputnik V for the potential prevention of COVID-19 infection Coronavirus disease 19 infection Sputnik V alone COVID19 Spike glycoprotein modulator Gamalei Institute of Epidemiology and Microbiology Philippines Phase 3 Clinical Recruiting 1 2020-10-19
A phase III clinical trial of Sputnik V for the potential prevention of COVID-19 infection Coronavirus disease 19 infection Sputnik V alone COVID19 Spike glycoprotein modulator Gamalei Institute of Epidemiology and Microbiology United Arab Emirates, Saudi Arabia 2020-10-13 Phase 3 Clinical Recruiting 2 2020-10-19
A clinical trial of ASLAN-003 for the treatment of Covid-19 and other viral infections Coronavirus disease 19 infection, Viral infection ASLAN-003 alone Dihydroorotate dehydrogenase inhibitor, p53 tumor suppressor protein stimulator ASLAN Pharmaceuticals Pte Ltd Phase Not Applicable Planned 0 2020-10-19
Cohort survey of healthcare workers with COVID-19 infection Coronavirus disease 19 infection Healthy volunteers accepted Chiba University Graduate School of Medicine Japan 2020-05-19 2020-06-11 UMIN000042142 Phase Not Applicable Completed 1 103 Taka-aki Nakada, Takeo Kurita 2020-10-21
An observational, case report to determine the diagnosis and management of upper gastrointestinal bleeding caused by SARS-CoV-2 infection during hospitalization Coronavirus disease 19 infection, Gastrointestinal bleeding Yunnan white drugs alone, gastroscopy alone, Variable regimens including aluminum phosphate , esomeprazole , octreotide acetate , thrombin Factor IIa agonist, H+ K+ ATPase inhibitor, Somatostatin receptor agonist Sun Yat-Sen University Phase Not Applicable Status not specified 0 1 2020-10-21
Evaluation of Respiratory profile and radiological changes in patients after recovery from COVID-19 Coronavirus disease 19 infection nintedanib alone, pirfenidone alone CSF-1 antagonist, FGF receptor antagonist, FGF1 receptor antagonist, FGF2 receptor antagonist, FGF3 receptor antagonist, Flt3 tyrosine kinase inhibitor, Lck tyrosine kinase inhibitor, Lyn tyrosine kinase inhibitor, PDGF receptor alpha antagonist, PDGF receptor antagonist, PDGF receptor beta antagonist, Src tyrosine kinase inhibitor, TGF beta receptor antagonist, VEGF receptor antagonist, VEGF-1 receptor antagonist, VEGF-2 receptor antagonist, VEGF-3 receptor antagonist, p38 MAP kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences India 2020-10-22 CTRI/2020/10/028372 Phase 4 Clinical Not yet recruiting 1 500 Anant Mohan 2020-10-20
Experiences among nurses caring patients with COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Manipal Academy of Higher Education India 2020-10-30 CTRI/2020/10/028373 Phase Not Applicable Not yet recruiting 1 30 Dr Leena Sequira, SHALINI G NAYAK 2020-10-20
A Clinical Study to Evaluate the Safety and Efficacy of CoviTone in Mild to Moderate COVID patients Coronavirus disease 19 infection CoviTone alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) India 2020-10-22 CTRI/2020/10/028376 Phase 2 Clinical Not yet recruiting 1 80 Dr M E Mohan, Jestin V Thomas 2020-10-20
KluT: COVID-19 Cluster in Temerloh: Is it related to tabligh? Coronavirus disease 19 infection 2020-10-13 2021-02-08 55897, KluT, NMRR-20-2208-55897 Phase Not Applicable Recruiting 0 3 Months Dr. Safaridah binti Anuar 2020-10-20
PVAS COVID-19: COVID-19: Public Awareness, Perception and Impact on Pharmacy Value Added Services (PVAS) in Kedah, Malaysia Coronavirus disease 19 infection Malaysia 2020-10-15 2021-06-30 55892, NMRR-20-2195-55892, PVAS COVID-19 Phase Not Applicable Not yet recruiting 1 8 Months Mrs Nurliana Binti Abdul Latif, norazila bt abdul ghani 2020-10-19
Effect of remdesivir in COVID-19 Coronavirus disease 19 infection remdesivir alone COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ahvaz University of Medical Sciences Iran 2020-09-27 IR.AJUMS.REC.1399.407, IRCT20200404046937N5 Phase 2/Phase 3 Clinical Recruiting 2 50 Dr Fatemeh Ahmadi, Mehdi Ahmadi Moghadam, Mehran Varnaseri, Mehran Varnasseri, Roohangiz Nashibi 2020-10-19
Cope-Corona: Identifying and strengthening personal resources to cope with the corona pandemic Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression, Psychiatric disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tongji Hospital China 2020-08-01 2023-07-31 ChiCTR2000038929, Cope-Corona Phase Not Applicable Not yet recruiting 1 36 Months 600 Heng Wu, Zheng Lu 2020-10-19
COVADIS study: COVID-19 Epidemic in West Africa (WA): infection dynamics and diagnostic approaches Coronavirus disease 19 infection COVID test kit alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Medical Research Council Unit, The Gambia European and Developing Countries Clinical Trials Partnership Gambia 2020-10-12 COVADIS study, PACTR202010472402152 Phase Not Applicable No longer recruiting 1 1100 Annette Erhart, Bakary Conteh, Vivat Thomas Njie 2020-10-19
ANTICOV IMMUNO: The impact of COVID-19 treatment on the type, strength and duration of antibody and cellular immune responses in SARS-CoV-2 patients in sub-Saharan Africa Ancillary Study of the ANTICOV Study: An open-label, multicentre, randomised, adaptive platform trial of the safety and efficacy of several therapies, including antiviral therapies, versus control in mild / moderate cases of COVID-19 Coronavirus disease 19 infection hydroxychloroquine alone, lopinavir + ritonavir alone HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bernhard-Nocht-Institute for Tropical Medicine, Drugs for Neglected Diseases Initiative, Ifakara Health Institute, Institute of Tropical Medicine Egypt 2020-09-21 ANTICOV IMMUNO, PACTR202010781639956 Phase Not Applicable Recruiting 1 1000 Gemma Moncunill, James Arkinstall, Nathalie StrubWourgaft 2020-10-20
A clinical trial to evaluate the efficacy of polyvalent highdosage intravenous immunoglobulin to stabilize or improve the health of COVID-19 patients Coronavirus disease 19 infection polyvalent high-dosage intravenous immunoglobulin alone Grifols SA Spain Phase Not Applicable Planned 1 2020-10-19
KoCo19-CED-1: Clinical care situation, health problems and psychosocial burdens during the COVID-19-pandemic in patients with chronic inflammatory bowel disease (IBD) - Part 1: Baseline survey and seroprevalence of SARS-CoV-2 antibodies compared to Munich population cohort (KoCo19) Coronavirus disease 19 infection, Inflammatory bowel disease blood test alone Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Klinikum der Universitat Muenchen Germany 2020-07-04 20-523, DRKS00021698, DRKS00022155, KoCo19-CED-1 Phase Not Applicable Recruiting 2 400 Elisabeth Klucker, Leandra Koletzko, Sibylle Koletzko, Simone Breiteneicher, Tobias Schwerd 2020-10-20
PRASACT: Clinical study to evaluate the effect of Ayurveda intervention as a prophylaxis for COVID-19 in Healthcare workers Coronavirus disease 19 infection Variable regimens including Amritotaram Kashayam Prakshepa , Chywanaprasha , Dasamoola Katutrayam Kashayam , Dhanvantaram Gutika , GuduchyAdi Kashayam Prakshepa , Haridrakhandam , Indukantam Kashayam , Nayopayam KS Prakshepa , Sudarshana Ghana Vati , Vasaristam+Kanakasavam , VidAryAdi KS Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ministry of Ayush India 2020-10-30 CTRI/2020/10/028424, PRASACT Phase 3 Clinical Not yet recruiting 1 200 Dr Zankhana Buch 2020-10-19
A clinical study to see the effects and safety of PNB-001 in patients with moderate COVID-19 infection Coronavirus disease 19 infection PNB-001 alone, Standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Byramjee Jeejeebhoy Govt Medical College and Sassoon General Hospitals India 2020-10-28 BCR-PNB-001, CT/ND/95/2020, CTRI/2020/10/028423 Phase 2 Clinical Not yet recruiting 1 40 Dr Neeta Nargundkar, Dr Pradnya Bhalerao 2020-10-20
Effect of COVID-19 on lymphocyte and eosinophil count Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences Patna India 2020-10-24 CTRI/2020/10/028422 Phase Not Applicable Not yet recruiting 1 150 DR AMARJEET KUMAR 2020-10-21
The effect of synbiotic on inflammatory markers and clinical manifestations in patients with COVID-19 Coronavirus disease 19 infection Lactocar synbiotic alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Isfahan University of medical Sciences Iran 2020-10-22 IR.MUI.MED.REC.1399.204, IRCT20200923048815N1 Phase 2/Phase 3 Clinical Not yet recruiting 1 80 Majid Aghadavood Marnani, Masha Khodadoostan Shahraki, Shaghayegh Haghjoy Javanmard 2020-10-19
SaNPS: Stress and neuropsychiatric symptoms/disorders (ie, functional brain diseases): COVID-19 as a source of stress Acute stress disorder, Coronavirus disease 19 infection group wellbeing therapy group wellbeing therapy alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Xuanwu Hospital Of Capital Medical University China 2020-01-04 2021-01-04 ChiCTR2000039079, SaNPS Phase Not Applicable Recruiting 1 12 Months 400 Hongxing Wang 2020-10-20
PAP SURVEY: A Survey of Psychological Distress and Its Associated Factors Among Health Service Providers Amidst the Covid-19 Pandemic in Malaysia Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression Healthy volunteers accepted Selayang Hospital Malaysia 2020-11-10 2020-12-16 56529, NMRR-20-2235-56529, PAP SURVEY Phase Not Applicable Status not specified 1 1 Month Dr Muhammad Haniff Bin Abdullah 2020-10-21
Persuasion in Medicine: Experimental Evidence on Sender and Signal Effects Coronavirus disease 19 infection Video about safety and effectiveness alone, direct messaging on COVID-19 vaccine safety and efficacy alone Healthy volunteers accepted, Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Harvard University Massachusetts Institute of Technology, Stanford University US 2019-12-20 2021-02-15 IRB19-1424, NCT04160975 Phase Not Applicable Recruiting 1 13 Months 3350 2020-10-19
Kap of New Normal among HCW's in Hospital Kuala Lumpur and Hospital Sungai Buloh Regarding Covid-19 Coronavirus disease 19 infection University of Malaya Malaysia 2020-11-01 2021-10-31 NMRR-20-2224-56820 Phase Not Applicable Status not specified 2 12 Months Dr Sri Viknarajan A/L Puvendran 2020-10-16
COVID19-MSK INJECTION Coronavirus disease 19 infection, Rheumatoid arthritis HOSPITAL QUEEN ELIZABETH II Malaysia 2020-10-31 2021-08-02 NMRR-20-2221-56202 Phase Not Applicable Status not specified 1 9 Months MOHAMAD AZWAN BIN AZIZ 2020-10-20
EDWH COVID-19 Coronavirus disease 19 infection Melaka Hospital Malaysia 2020-10-25 2020-12-31 NMRR-16-2910-29170 Phase Not Applicable Status not specified 5 2 Months Madam NOORHALIZA BT ALI 2020-10-20
A study to assess safety and efficacy of natural killer cells in the treatment of covid-19 Coronavirus disease 19 infection K-NK-ID101 alone Abigail Wexner Research Institute, Kiadis Pharma BV Phase Not Applicable Planned 0 2020-10-16
The COVID PROFILE study Coronavirus disease 19 infection Walter and Eliza Hall Institute of Medical Research Royal Melbourne Hospital, The Peter Doherty Institute for Infection and Immunity, University of Melbourne Phase Not Applicable Status not specified 0 300 Dr Vanessa Bryant, Professor Ivo Mueller 2020-10-16
NCoV-Radi: NCoV-Radi Coronavirus disease 19 infection chest radiography alone, computed tomography imaging alone The University of Hong Kong Hong Kong 2020-02-10 2021-01-31 HKUCTR-2850, NCoV-Radi, UW 20-115, v1 Phase Not Applicable Recruiting 1 11 Months 50 Dr. Ming-Yen Ng, HKUCTR Administrator 2020-10-19
ICARD: The impact of COVID-19 pandemic-related activity restriction on the outcomes of chronic obstructive lung disease Chronic obstructive pulmonary disease, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Nagoya University Nagoya University Graduate School of Medicine Japan 2020-09-01 2023-03-31 ICARD, UMIN000042106 Phase Not Applicable Recruiting 1 31 Months 150 Akira Ando, Naozumi Hashimoto 2020-10-20
A Phase I, Open-Label, Parallel-Group, Single-Dose Study to Evaluate the Pharmacokinetics of Remdesivir and Metabolites in Participants with Normal Renal Function and Renal Impairment Coronavirus disease 19 infection remdesivir alone COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Gilead Sciences Inc Australia, New Zealand, Puerto Rico, Germany, US 2020-11-02 ACTRN12620001048976p Phase 1 Clinical Not yet recruiting 5 80 Dr Christian Schwabe 2020-10-19
REMOTE CONTROL: Home-based blood pressure monitoring of Hypertensive Diseases in Pregnancy - A randomized, controlled trial Coronavirus disease 19 infection, Hypertension, Pre-eclampsia Home-based blood pressure monitoring -app alone, automated BP machine alone, education and training alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Campbelltown Hospital, Liverpool Hospital Heart Research Institute Ltd Australia 2021-01-01 ACTRN12620001049965p, REMOTE CONTROL Phase Not Applicable Not yet recruiting 1 300 Dr Theepika Rajkumar 2020-10-21
Extended SIR model Coronavirus disease 19 infection Clinical Research Centre 2020-10-14 2021-10-13 56878, NMRR-20-2217-56878, model01 Phase Not Applicable Status not specified 0 12 Months Pharmacist Law Kian Boon 2020-10-19
SERVQUAL Model in Hospital Coronavirus disease 19 infection health management alone Universiti Kebangsaan Malaysia Malaysia 2020-11-01 2021-03-31 54898, NMRR-20-2131-54898 Phase Not Applicable Not yet recruiting 34 5 Months Siti Nurfadhilah binti Arsad 2020-10-19
Clinical study of an Ayurveda formulation containing Gold and Indian Gooseberry along with Tulasi juice as an add on therapy in standard care of COVID 19 patients Coronavirus disease 19 infection Swarna Amalaki alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ministry of Ayush Acharya Vinoba Bhave Rural Hospital India 2020-11-02 CTRI/2020/10/028414 Phase 2 Clinical Not yet recruiting 0 60 Anjalee Chiwane, Jyothy K B 2020-10-20
Psychological responses of medical staff during COVID-19 and the adjustment effect of brief mindfulness meditation Coronavirus disease 19 infection brief mindfulness meditation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Naval Medical Research Institute of PLA National Natural Science Foundation of China China 2021-01-01 2021-12-31 ChiCTR2000039002 Phase 0 Clinical Not yet recruiting 1 12 Months 400 Liu Yunzi 2020-10-19
School teachers experience in online teaching during this COVID-19 situation Acute stress disorder, Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Manipal Academy of Higher Education India 2020-10-13 CTRI/2020/10/028412 Phase Not Applicable Not yet recruiting 1 200 JOSHUA RAYMOND ANDRADE, UMESH THONSE 2020-10-21
A Phase III clinical trial for inactivated novel coronavirus pneumonia (COVID-19) vaccine (Vero cells) Coronavirus disease 19 infection, Viral pneumonia COVID-19 vaccine (inactivated, Vero cells/intramuscular), Wuhan Institute of Biological Products/Wuhan Institute of Virology, CAS alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) China National Biotec Group, Wuhan Institute of Biological Products Co Ltd Morocco 2020-09-02 2020-12-31 ChiCTR2000039000 Phase 3 Clinical Recruiting 1 3 Months 600 Professeur Abouqal Redouane, Wei Chen 2020-10-19
A population based survey on COVID-19 infection in Goa state among both urban and rural population Coronavirus disease 19 infection Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Government of Goa India 2020-10-16 CTRI/2020/10/028384 Phase Not Applicable Not yet recruiting 1 1000 Dr Dhananjay Lad, Dr Vijaykumar Patil 2020-10-20
Clinical characteristics and laboratory parameters of COVID-19 patients on oxygen Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) National Cancer Institute, Jhajjar, AIIMS India 2020-10-20 CTRI/2020/10/028340 Phase Not Applicable Not yet recruiting 1 100 Dr Anuja Pandit 2020-10-20
To study the relationship between spirituality,hope, distress and ability to bounce back from stress among family members of recovered COVID-19 patients Acute stress disorder, Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Government Medical College and Hospital,Chandigarh India 2020-11-01 CTRI/2020/10/028339 Phase Not Applicable Not yet recruiting 1 30 Anushka Negi, Dr Ajeet Sidana, Dr Manoj Kumar 2020-10-19
The Provider Insurance Revenue Study in Healthcare Providers in the United States of America Coronavirus disease 19 infection University of California Irvine US 2020-10-01 2021-10-15 NCT04587245, PIRSTUDY Phase Not Applicable Recruiting 1 12 Months 100 Charles Bronson, Charles Bronson, MBA, Henry Broeska, Henry Broeska, PhD, Sheridan Merrick, BA 2020-10-16
NEUROCOV-19: Investigation of COVID-19 associated neurological comorbidities Coronavirus disease 19 infection, Neurological disease electrophysiological examination alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitatsklinikum Essen Germany 2020-10-25 20-9284-BO, DRKS00023312, NEUROCOV-19 Phase Not Applicable Recruiting 1 250 Mark Stettner, Michael Fleischer 2020-10-21
Dyhor-19: Diagnosis of Endocrine Dysfunctions in COVID-19 Coronavirus disease 19 infection, Endocrine disease Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Montpellier France 2020-03-01 2020-05-30 Dyhor-19, NCT04587375, RECHMPL20_0205 Phase Not Applicable Completed 1 2 Months 50 Philippe GUILPAIN, MD, PhD 2020-10-16
PROSPER: Pregnancy Outcomes During the Pandemic: Using Placental Pathology and Gene Expression to Understand Fetal Risk Coronavirus disease 19 infection Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Prisma Health-Upstate US 2020-08-04 2021-09-30 NCT04585945, PRO00101090, PROSPER Phase Not Applicable Recruiting 3 13 Months 100 Jessica Britt, PhD, Jessica L Britt, PhD 2020-10-16
Development and Use of a Post-COVID-19 Quality of Life Patient-reported Outcome Measure Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) UK 2020-10-07 2025-10-31 MED-ASST 33, NCT04586413 Phase 1/Phase 2 Clinical Recruiting 1 60 Months 100 Ravi Jandhyala, Rose Watson 2020-10-16
An observational study to determine the postdischarge venous thromboembolism rates following hospital admission with COVID-19 Coronavirus disease 19 infection, Thromboembolism venous thromboembolism analysis alone Kings College Hospital NHS Trust Phase Not Applicable Status not specified 0 2020-10-18
MySteps-CoV: eHealth Intervention on Physical Activity for Type 2 Diabetics - Frustrated by COVID-19 Coronavirus disease 19 infection, Non-insulin dependent diabetes ExSed app alone, Usual care alone, counselling contacts alone, eHealth alone, hip-worn accelerometer alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) UKK-instituutti North Karelia Central Hospital, University Of Eastern Finland Finland 2019-03-06 2020-10-31 MYSTEPS ETL 303/2017, MySteps-CoV, NCT04587414 Phase Not Applicable No longer recruiting 1 19 Months 122 Harri Sievanen, Tommi Vasankari, MD, PhD 2020-10-20
Improving the Mental Health of Resident Physicians and Fellows Through Transcendental Meditation Acute stress disorder, Coronavirus disease 19 infection Transcendental meditation alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Arizona US 2020-11-30 2021-12-31 2008969193, NCT04586309 Phase Not Applicable Not yet recruiting 1 13 Months 50 Alison Sutton-Ryan, LCSW, Rachel E M Cramton, MD 2020-10-19
Endothelial dysfunction in severe COVID-19 disease Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute Of Medical Sciences, Rishikesh India 2020-10-19 CTRI/2020/10/028361 Phase Not Applicable Not yet recruiting 1 40 Rohit Walia 2020-10-19
Psychiatric sequelae in COVID-19 infection recovered resident doctors and interns of a tertiary health care hospital Coronavirus disease 19 infection, Psychiatric disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Seth GS Medical College India 2020-10-19 CTRI/2020/10/028360 Phase Not Applicable Not yet recruiting 1 60 Dr Neena S Sawant 2020-10-16
MoxiCov: Feasibility and Impact of Remote Oximetry in Patients Hospitalized With COVID-19 Coronavirus disease 19 infection, Hypoxia Digital oximeter alone, cardiac frequency monitoring alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo Brazil 2020-06-22 2021-06-22 5058/20/087, MoxiCov, NCT04587921 Phase Not Applicable Recruiting 1 12 Months 90 Daniel Queiróz, PhD, Diego Prieto, Msc, Geraldo Lorenzi Filho, Geraldo Lorenzi, M.D. PhD, Luciano Drager, M.D. PhD, Pedro Genta, M.D PhD 2020-10-16
A clinical trial to evaluate the effectiveness and safety of Vedicinals-9- a Herbal formulation in mild to moderate COVID-19 patients Coronavirus disease 19 infection Vedicinals-9 alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) India 2020-10-19 CTRI/2020/10/028364, EPRD0202-010920 Phase 2 Clinical Not yet recruiting 2 124 Dr Govinda Narke, Dr Nitin Shinde, Yogendra Kumar Choudhary 2020-10-16
The barriers encountered by health-service providers while giving healthcare to patients admitted to COVID hospitals of Odisha Coronavirus disease 19 infection online self-administered questionnaire alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Kalinga Institute of Medical Sciences India 2020-11-01 CTRI/2020/10/028363 Phase Not Applicable Not yet recruiting 1 1000 Nipa Singh 2020-10-16
The Study of 'Gam-COVID-Vac' Vaccine Against COVID-19 With the Participation of Volunteers of >/= 60 years old Coronavirus disease 19 infection Sputnik V alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gamalei Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation Collaborator Russian Federation 2020-10-15 2020-12-20 05-GAM-COVID-VAC-2020, NCT04587219 Phase 2 Clinical Not yet recruiting 1 2 Months 110 Inna Dolzhikova, PhD, Nikita Lomakin, MD, PhD 2020-10-21
Study to assess the efficacy of deep breathing Pranayama technique in addition to conventional allopathic treatment in management of COVID-19 Coronavirus disease 19 infection deep breathing Pranayama alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) India 2020-10-15 CTRI/2020/10/028362, JRH/IEC/2020/COVID19/Pranayama breathing technique Phase Not Applicable Not yet recruiting 1 278 Dr Anuja Santosh Kulkarni 2020-10-19
Improving Cancer Screening and Prevention During the COVID-19 Pandemic in Underserved Populations of Rhode Island Breast tumor, Colorectal tumor, Coronavirus disease 19 infection Cancer screening alone, Colonoscopy alone, Informational videos and social media campaign alone, Mammogram alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rhode Island Hospital US 2020-08-28 2022-09-01 1613494-3, NCT04587258 Phase Not Applicable Recruiting 1 24 Months 100 Cristina Pacheco, MD, Don Dizon, MD, Howard Safran, MD 2020-10-17
Study to Assess the Effect of Meplazumab on COVID-19 Coronavirus disease 19 infection meplazumab alone, standard of care alone Basigin inhibitor, COVID19 Spike glycoprotein inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Pacific Meinuoke Biopharmaceutical 2020-10-30 2021-04-30 MPZ-II-02, NCT04586153 Phase 2/Phase 3 Clinical Not yet recruiting 0 6 Months 456 Shuangshuang Liu, Xiaochun Chen 2020-10-16
ETHICOVID: Operation of the GHPSJ Clinical Ethical Reflection Assistance Group During the COVID-19 Period Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Groupe Hospitalier Paris Saint-Joseph France 2020-11-09 2022-04-30 ETHICOVID, ETHICOVID, NCT04586140 Phase Not Applicable Not yet recruiting 1 17 Months 30 Helene BEAUSSIER, PharmD, pHD, Marie-Lorraine de WARREN, Nurse 2020-10-16
CoCovSDRA: Effect of Corticosteroid Treatment on Prognosis in ARDS Secondary to Covid-19 Coronavirus disease 19 infection, Respiratory distress syndrome corticosteroid treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Hospital, Nancy, France France 2020-03-01 2020-12-31 2020PI109, CoCovSDRA, DUBOST_2020_PI_109, NCT04586114 Phase Not Applicable No longer recruiting 1 10 Months 200 Sebastien GIBOT 2020-10-20
A trial to evaluate ALF-1001 for the preventing the spread of COVID-19 Coronavirus disease 19 infection ALF-1001 alone IL-22 antagonist, IL-23 antagonist, Interferon alpha 14 ligand, Interleukin 17A ligand inhibitor, Interleukin 17F ligand inhibitor, TNF alpha ligand inhibitor ILC Therapeutics Ltd Phase Not Applicable Planned 0 2020-10-15
A phase III clinical trial to evaluate the efficacy of SARS-CoV-2 peptide vaccine (li-Key, COVID-19), Generex for the potential prevention of COVID-19 infection Coronavirus disease 19 infection SARS-CoV-2 peptide vaccine (li-Key, COVID-19), Generex alone Generex Biotechnology Corp Bintai Kinden Corp US Phase 3 Clinical Planned 1 2020-10-15
A case-control study of lenzilumab in patients with severe and critical COVID-19 Coronavirus disease 19 infection lenzilumab alone GM-CSF ligand inhibitor, Immunoglobulin G1 modulator, Immunoglobulin kappa modulator Humanigen Inc Phase Not Applicable Status not specified 0 39 2020-10-15
A patient case report to evaluate lenzilumab in severe and critical COVID-19 patient Coronavirus disease 19 infection lenzilumab alone GM-CSF ligand inhibitor, Immunoglobulin G1 modulator, Immunoglobulin kappa modulator Male, European Ancestry Humanigen Inc Phase Not Applicable Status not specified 0 2020-10-15
VEGF and sFlt-1 Levels in the Pathogenesis and Severity of COVID-19 Disease Cardiac failure, Cardiovascular disease, Coronavirus disease 19 infection, Multiple organ failure, Renal failure, Respiratory failure Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Alabama at Birmingham US 2020-05-22 2023-05-20 IRB-300005378, NCT04587323 Phase Not Applicable Recruiting 1 35 Months 100 Dylan Addis, MD, Shanna H Graves 2020-10-16
A clinical trial of TLC-19 for the treatment of covid-19 Coronavirus disease 19 infection TLC-19 alone Healthy volunteers accepted Taiwan Liposome Co Phase 1 Clinical Planned 0 30 2020-10-15
MOR: Mouth Rinses for Inactivation of COVID-19 Coronavirus disease 19 infection Betadine gargle alone, Colgate Optic White alone, Colgate Total mouthwash alone, Listerine alone, Peridex alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of North Carolina US 2020-10-31 2023-09-30 20-2040, MOR, NCT04584684 Phase 2 Clinical Not yet recruiting 1 35 Months 480 Laura Jacox, DMD, PhD, S.T. Phillips, Wendy Lamm 2020-10-16
Outcomes of and Prognosis Factors for COVID-19 Patients - An Observational Study Coronavirus disease 19 infection Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Xiangya Hospital Of Central South University China 2020-01-17 2021-02-28 ChiCTR2000038943 Phase Not Applicable Recruiting 1 13 Months 233 Suixin Liu, Yaoshan Dun 2020-10-16
Gynecological Laparoscopic Surgery during COVID-19 Pandemic Coronavirus disease 19 infection, Gynecological disorder Putrajaya Hospital Malaysia 2020-09-30 2020-10-30 NMRR-20-2129-56450 Phase Not Applicable Status not specified 1 1 Month Dr Raimi Zamriah Hasan, Dr Tunisha a/p Ganisakran 2020-10-16
Biochemistry and hematology sample handling during COVID-19: Hospital Sungai Uloh experience Coronavirus disease 19 infection Hospital Sungai Buloh Malaysia 2021-01-25 2021-01-27 56713, NMRR-20-2127-56713 Phase Not Applicable Status not specified 1 Dr NUR AMALINA BINTI YUSOFF, Dr Sharifah Khairul Atikah 2020-10-19
A large, pragmatic, open-label study to assess efficacy and safety of bamlanivimab monotherapy or combination therapy with etesevimab Coronavirus disease 19 infection bamlanivimab alone, bamlanivimab plus etesevimab COVID19 Spike glycoprotein modulator Eli Lilly & Co Phase Not Applicable Planned 0 2020-10-15
ACTIV-3: A clinical trial of bamlanivimab for the treatment of patients with ambulatory and hospitalized COVID-19 patients Coronavirus disease 19 infection bamlanivimab plus remdesivir COVID19 Spike glycoprotein modulator, COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Eli Lilly & Co, National Institutes of Health ACTIV-3 Phase Not Applicable Suspended 0 1000 2020-10-20
BLAZE-4: A clinical trial to evaluate IV doses of etesevimab in combination with bamlanivimab Coronavirus disease 19 infection bamlanivimab plus etesevimab COVID19 Spike glycoprotein inhibitor, COVID19 Spike glycoprotein modulator Eli Lilly & Co BLAZE-4 Phase Not Applicable Planned 0 2020-10-15
An observational study on the clinical characteristics of metastatic prostate cancer patients infected with COVID-19 in South Italy Coronavirus disease 19 infection, Hormone refractory prostate cancer, Metastatic prostate cancer LHRH agonist therapy alone, chemotherapy alone, enzalutamide alone, hormonal treatment alone Androgen receptor antagonist, Cytochrome P450 3A4 stimulator, DNA binding protein inhibitor, Prostate specific antigen modulator, Translocation associated protein inhibitor Male University of Molise Italy Phase Not Applicable Status not specified 1 2 2020-10-15
A Phase II Study of RTB-101 as COVID-19 Post-Exposure Prophylaxis in Older Adults Coronavirus disease 19 infection dactolisib alone Phosphoinositide 3-kinase inhibitor, mTOR complex 1 inhibitor, mTOR complex 2 inhibitor Aged Adults (65-79 yrs), Elderly Adults (80 and over) resTORbio Inc Harvard Medical School, National Institute on Aging, University of Connecticut Health Center US 2020-10-31 2021-02-28 3R01AG064802-02S1, NCT04584710, RTB101-211 Phase 2a Clinical Recruiting 2 4 Months 60 Lisa Kenyon-Pesce, Medical Monitor, Peggy Gagnon 2020-10-20
D-dimer Adjusted Versus Therapeutic Dose Low-molecular-weight Heparin in Patients With COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia D-dimer and weight adjusted therapy alone, enoxaparin sodium alone Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ain Shams University Egypt 2020-08-01 2020-12-31 FMASU P35/ 2020, NCT04584580 Phase 4 Clinical Recruiting 1 5 Months 50 Ashraf Madkour, Fatma Soliman E Ebeid 2020-10-16
OD-doxy-PNVCOV Old Drug 'DOXY' for Prevention of New Virus Virus OD-doxy-PNV Coronavirus disease 19 infection doxycycline plus zinc Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hopital Militaire Principal d'instruction de Tunis Dacima Consulting Tunisia 2020-10-30 2021-03-01 NCT04584567, UR17DN05 Phase 3 Clinical Not yet recruiting 1 4 Months 1100 Batikh R Riadh, physican, Ben Moussa M mohamed, physican, Ferjani M Mustapha, physican, Gharsallah H Hedi, physican, Mrabet A Ali, physican, Stambouli N nejla, phd, Youssfi MA Mohamed Al, physican 2020-10-15
The Effect of Aerobic Exercise on Immune Biomarkers and Symptoms Severity and Progression in Patients With COVID-19: A Pilot, Randomized, Control Trial Coronavirus disease 19 infection, Gastrointestinal disease, Upper respiratory tract infection, Viral pneumonia Moderate Intensity Aerobic Exercises alone, aerobic exercise alone, hydroxyclorocin sulphate (Plaquenil) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Turkey 2020-01-01 2020-10-01 AEROBIC EXERCISE, COVID-19, NCT04581291 Phase Not Applicable Completed 1 9 Months 30 Motaz Alawna 2020-10-15
LIFTCOVID: Lift Mobile Mindfulness for COVID-19 Distress Symptoms Coronavirus disease 19 infection, Depression, Generalized anxiety disorder, Respiratory distress syndrome Lift mobile mindfulness program app alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Duke University National Center for Complementary and Integrative Health US 2020-11-01 2021-09-30 3U01AT009974-03S1, LIFTCOVID, NCT04581200, PRO00106306 Phase Not Applicable Not yet recruiting 4 11 Months 300 Allie Frear, Catherine L Hough, MD, MSc, Christopher Cox, MD, Christopher E Cox, MD, Jeffrey McKeehan, Lee Kamphuis, MPH, Madeleine McDougal, Marc Moss, MD, Theodore Iwashyna, MD, PhD 2020-10-16
SYNBIOTIC COV STUDY: An Evaluation of a Synbiotic Formula for Patients With COVID-19 Infection Coronavirus disease 19 infection health supplements (Synbiotic) alone, standard care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chinese University of Hong Kong Hong Kong 2020-08-13 2022-04-30 NCT04581018, SYNBIOTIC COV STUDY, SYNBIOTIC COV STUDY Phase Not Applicable Recruiting 1 20 Months 50 Amy Li, Kitty Cheung, Siew Chien Ng, Siew Chien Ng, PhD 2020-10-16
Clinical trail of remdesivir in Covid-19 patinets Coronavirus disease 19 infection, Viral pneumonia remdesivir alone COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hungary 2020-10-12 2020-004928-42, REM-ENY-01 Phase 3 Clinical Recruiting 1 2000 CRO 2020-10-16
DYADS: Dysphagia and Dysphonia Outcomes in SARS CoV-2 (COVID-19) Infection Coronavirus disease 19 infection, Dysphagia, Dysphonia fiberoptic endoscopic evaluation of swallowing test alone, videofluoroscopy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cambridge University Hospitals NHS Foundation Trust UK 2020-09-15 2021-12-31 20/NW/0333, DYADS, NCT04584658 Phase Not Applicable Recruiting 1 15 Months 36 Andrie Schembri, BSc, Brian Fish, FRCS (ORL-HNS), Claudia Russell, MSc, Ekpemi Irune, Ekpemi Irune, FRCS (ORL-HNS), Liam Masterson, FRCS (ORL-HNS), Rachel Kyd, Sarah Pilsworth, MSc 2020-10-20
Patterns of Arrhythmias and Conduction Block in COVID-19 Patients and Its Relation to Myocardial Injury Detected by Cardiac Magnetic Resonance Atrioventricular block, Coronavirus disease 19 infection, Heart arrhythmia, Heart injury SSFP sequence based cine imaging alone, cardiac magnetic resonance imaging alone, gadolinium alone, myocardial perfusion imaging alone, tissue characterization imaging alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assiut University Egypt 2020-11-01 2024-01-01 ARRHYTHMIAS IN COVID-19, NCT04584411 Phase Not Applicable Not yet recruiting 1 38 Months 50 Ahmed AR Hassaan, bachelor, Alaa A El-Moniem, Doctorate, Doaa A Fouad, Doctorate, Maram M Shafiq, student, Mohamed A.H Abdelhafez, Doctorate, Shimaa S Khider, Doctorate 2020-10-15
Ain Shams University Experience: Clinical Determinants of Hospitalized COVID-19 Patients Coronavirus disease 19 infection laboratory test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ain Shams University Egypt 2020-06-27 2020-12-30 FMASU P30/ 2020, NCT04584606 Phase Not Applicable Recruiting 1 6 Months 100 Ashraf Elmaraghy, Fatma Soliman E Ebeid 2020-10-16
COPP2-study: Clinical features of COVID-19 in pediatric patients, long-term effects Coronavirus disease 19 infection Amsterdam UMC Netherlands 2020-10-01 2022-03-01 COPP2-study, NL8926 Phase Not Applicable Not yet recruiting 1 17 Months 120 Caroline Kosterink-Brackel 2020-10-15
LIVECOVIDFREE: Lung Structure-Function In Survivors of Mild and Severe COVID-19 Infection Coronavirus disease 19 infection 6 min walk test alone, biological sampling alone, computed tomography alone, forced oscillation technique alone, hyperpolarized xenon-129 alone, magnetic resonance imaging alone, plethysmography alone, spirometry alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Western Ontario London Health Sciences Centre Research Inc Canada 2020-12-01 2024-12-01 LIVECOVIDFREE, NCT04584671, ROB0050 Phase Not Applicable Not yet recruiting 1 48 Months 200 Angela Wilson, RRT, Grace E Parraga, PhD 2020-10-15
ReCOVer: Cognitive Behavioral Therapy for post-COVID-19 fatigue Coronavirus disease 19 infection, Fatigue internet-based cognitive behavioral therapy (iCBT) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Amsterdam UMC The Netherlands Organisation for Health Research and Development Netherlands 2020-10-05 2022-10-05 NL8947, ReCOVer Phase Not Applicable Recruiting 1 24 Months 114 Tanja Kuut 2020-10-16
COVSPERM: Pilot Study to Detect SARS-CoV-2 Virus in Sperm Coronavirus disease 19 infection blood sampling alone, nasopharyngeal sampling alone, saliva sampling alone, semen sampling alone, urine sampling alone Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Centre Hospitalier Universitaire de Toulouse France 2020-10-31 2022-02-28 2020-A01610-39, COVSPERM, NCT04584593, RC31/20/0202 Phase Not Applicable Not yet recruiting 1 16 Months 50 Louis BUJAN, PR, Louis BUJAN, Pr 2020-10-16
Investigation of Validity and Reliability of Post-COVID-19 Functional Status Scale Coronavirus disease 19 infection Data collection alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hacettepe University Turkey 2020-09-02 2021-12-02 GO 20/788, NCT04584450 Phase Not Applicable Recruiting 1 15 Months 100 Aslihan Cakmak, Aslıhan Çakmak, Deniz Inal-Ince, Ebru Calik Kutukcu, Ebru Çalık-Kütükcü, Esra Kınacı, Gülay Sain-Güven, Lale Özışık, Melda Saglam, Naciye Vardar-Yagli, Nursel Çalık-Başaran, Oğuz Abdullah Uyaroğlu 2020-10-15
COVIRIC: Sars-Cov-2 Viral Infection (COVID-19) in Patients With Chronic Inflammatory Rheumatism Coronavirus disease 19 infection, Rheumatoid arthritis, Spondylarthritis immune response assessment alone, immunosuppressive therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-06-11 2023-12-31 APHP200598, COVIRIC, NCT04584541 Phase Not Applicable Recruiting 1 42 Months 150 Adèle bellino, Corinne Miceli-Richard, MD, PhD 2020-10-17
Study to Evaluate the Safety, Pharmacokinetics and Efficacy of STI-2020 (COVI-AMG) in Outpatients With COVID-19 Coronavirus disease 19 infection COVI-AMG alone, standard of care alone COVID19 Spike glycoprotein inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sorrento Therapeutics Inc 2020-12-31 2021-04-30 AMG-COV-101, NCT04584697 Phase 1/Phase 2 Clinical Not yet recruiting 0 4 Months 50 Mike Royal, MD 2020-10-16
Prognostic Factors and Outcomes of COVID-19 Cases in Ethiopia Coronavirus disease 19 infection Ethiopian Public Health Institute Dutch Ministry of Health, Welfare and Sport Ethiopia 2020-10-30 2021-11-14 EPHI NATIONAL COHORT, NCT04584424 Phase Not Applicable Not yet recruiting 1 12 Months 6390 Masresha Tessema, Masresha Tessema, PhD, Saro Abdella, MPhil, Saro Abdella, mPhil 2020-10-15
An observational, clinical series study to evaluate the effect of sarilumab in patients with COVID‐19 pneumonia Coronavirus disease 19 infection, Viral pneumonia Variable regimens including azithromycin , cobicistat , darunavir , enoxaparin sodium , hydroxychloroquine , sarilumab Cytochrome P450 3 inhibitor, IL-6 receptor antagonist, Low molecular weight heparin San Giovanni di Dio Hospital Phase Not Applicable Status not specified 0 8 2020-10-14
An observational and single-center study of hydroxychloroquine treatment in COVID-19 in Wuhan, China Coronavirus disease 19 infection hydroxychloroquine alone Tongji Hospital China Phase Not Applicable Status not specified 1 30 2020-10-14
Telerehabilitation for elderly people with Alzheimer's disease and their caregivers Alzheimers disease, Coronavirus disease 19 infection Telerehabilitation alone, cognitive and multicomponent motor exercises alone, psychoeducation alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundação Universidade Federal De São Carlos Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Brazil 2020-09-20 2021-06-25 4.255.764, RBR-825p57, U1111-1252-3238, _89476318.0.0000.5504 Phase Not Applicable Recruiting 1 9 Months 48 Carla A. Andreatto, Carolina Tsen, Larissa Pires de Andrade 2020-10-19
A phase II clinical trial MVA-SARS-2-S vaccine for the potential prevention of COVID-19 infection Coronavirus disease 19 infection MVA-SARS-2-S alone COVID19 Spike glycoprotein modulator Universitätsklinikum Hamburg-Eppendorf Germany 2020-12-31 Phase 2 Clinical Planned 4 2020-10-14
Prolonged Prone Positioning for COVID-induced Acute Respiratory Distress Syndrome (ARDS): A Pilot Study Coronavirus disease 19 infection, Respiratory distress syndrome Prolonged Proned Positioning alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Alabama at Birmingham US 2021-01-31 2021-06-30 IRB-300005979, NCT04581811 Phase Not Applicable Not yet recruiting 1 5 Months 52 David B Page, M.D., David Page, Derek Russell, M.D., Mark Dransfield, M.D. 2020-10-15
coVIHd-19: Impact of the Epidemic of COVID-19 Infection Among People Living With HIV (SARS-CoV-2) Coronavirus disease 19 infection, HIV infection questionnaire alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier de Tourcoing France 2020-10-31 2021-12-31 NCT04581746, RIPH_2020_7, coVIHd-19 Phase Not Applicable Not yet recruiting 3 14 Months 1800 Emmanuelle AISSI, MD, Jean Luc SCHMIT, PU-PH, Pauline THILL, MD, Solange TREHOUX, PhD 2020-10-15
Group CBT For Perinatal Anxiety Coronavirus disease 19 infection Group Cognitive Behaviour Therapy for Perinatal Anxiety (CBT-PA) alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Manitoba Canada 2020-10-31 2021-09-30 H2020:095, NCT04581681 Phase Not Applicable Not yet recruiting 1 11 Months 50 Gillian Alcolado 2020-10-18
A phase Ib/IIa clinical study to assess VIR-7832 in the treatment of patients with SARS-CoV-2 infection Coronavirus disease 19 infection VIR-7832 alone COVID19 Spike glycoprotein modulator GlaxoSmithKline plc, Vir Biotechnology Inc 2020-12-31 Phase 1/Phase 2 Clinical Planned 0 2020-10-14
CAMELOT: Camostat Efficacy versus Placebo for Outpatient Treatment of COVID-19 Coronavirus disease 19 infection camostat mesylate alone Serine protease inhibitor, Transmembrane serine protease 2 inhibitor, Trypsin inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sagent Pharmaceuticals Inc US 2020-10-31 2021-01-31 CAMELOT, NCT04583592, NI03-CV19-001 Phase 2 Clinical Not yet recruiting 12 3 Months 300 Atasi Jana, M.D., Brett Foster, Cheryl Hargrove, Erin Kelly, Jackie Duckett, Janet Nuttall, M.P.H., Janett Jalil, Julie Lafave, Niurka Romero, Olia Nayor, Priscilla Hernandez, Rabia Gilani, Yelamis Cartaya, Yeslin Arias 2020-10-15
Mental Imagery to Increase Face Covering Use in UK-based Public Places During the COVID-19 Pandemic Coronavirus disease 19 infection Mental imagery alone, Process imagery alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of East London University of Manchester UK 2020-08-19 2020-12-01 ETH2021-0006, NCT04583449 Phase Not Applicable Recruiting 1 3 Months 250 Dominic Conroy, PhD 2020-10-15
ImmuneSense COVID-19 Study Coronavirus disease 19 infection T-Detect SARS-CoV-2 assay alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Adaptive Biotechnologies Corp Covance Inc US 2020-10-09 2021-01-09 NCT04583982, PRO-00781 Phase Not Applicable Not yet recruiting 1 3 Months 125 Jennifer Dines, MD, Jia Qadeer, Sarah Duffy, Thomas Manley, MD 2020-10-14
Validation of a Rapid, Non-invasive Point-of-care IVD Test for Diagnosis of SARS-COV-2 (COVID-19) Infection (EasyCov) Coronavirus disease 19 infection EasyCov IVD test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Firalis SAS Istanbul University Turkey 2020-10-31 2021-03-31 NCT04583319, ST0194 Phase Not Applicable Not yet recruiting 1 5 Months 160 Arif Atahan, Prof.MD, Rodwell Mkhwananzi, MD, Stéphanie Boutillier, PhD 2020-10-15
TeleCCCAP: Feasibility and Quality of TeleConsultation in Pediatric Anesthesia Anesthesia, Coronavirus disease 19 infection teleconsultation alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Centre Hospitalier Universitaire de Toulouse France 2020-10-07 2022-03-14 2020-A02275-34, NCT04583865, RC31/20/0220, TeleCCCAP Phase Not Applicable No longer recruiting 1 17 Months 400 KERN Delphine, MD 2020-10-13
Negative predictive value of the FebriDx host response point-of-care test in patients presenting to a single Australian Emergency Department with suspected COVID-19 Coronavirus disease 19 infection FebriDx finger prick test alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Planet Innovation Australia 2020-11-01 2022-05-31 ACTRN12620001029987p, ANZCTR379997 Phase Not Applicable Not yet recruiting 1 19 Months 300 Paul Buntine, Shelley Westgarth-Nugent 2020-10-15
BET-B; ACTIV-5/BET study: Big Effect Trial (BET-B) for the Treatment of COVID-19 Coronavirus disease 19 infection lenzilumab plus remdesivir COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, GM-CSF ligand inhibitor, Immunoglobulin G1 modulator, Immunoglobulin kappa modulator, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Humanigen Inc, National Institute of Allergy and Infectious Diseases National Institutes of Health US 2020-10-30 2021-07-01 20-0013B, BET-B, ACTIV-5/BET study, NCT04583969 Phase 2 Clinical Not yet recruiting 6 8 Months 200 20-0013 Central Contact 2020-10-20
Evaluation of the Performance of the Covid-19 Ag BSS Rapid Antigenic Test in Symptomatic Children in a Pediatric Emergency Department Coronavirus disease 19 infection Biosynex Covid-19 Ag-BSS test alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Centre Hospitalier Intercommunal Creteil France 2020-10-01 2021-01-01 NCT04583189, SPEEDYCOVI Phase Not Applicable Recruiting 1 3 Months 500 BISCARDI Sandra, MD, Camille JUNG, Ph D 2020-10-21
A clinical study to assess the efficacy and safety of Tinefcon in patients with moderate COVID-19 infection Coronavirus disease 19 infection Tinefcon alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Life Molecular Imaging India 2020-10-12 CTRI/2020/10/028335, Tinefcon/01/20 Phase 3 Clinical Not yet recruiting 4 60 Dr Alben Sigamani, Dr Mala Kaneria, Dr Mehul Shah, Dr Rahul Tambe, Mridul Sharma, Rajiv Salvi 2020-10-15
Prospective on evaluation of use of , “AyurCoro3” as an add on medication for the treatment purpose in COVID-19 patients Coronavirus disease 19 infection AyurCov3 alone, Standard of Care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) India 2020-10-13 CTRI/2020/10/028333 Phase 3 Clinical Not yet recruiting 1 500 Dr Nanasaheb Memane, Dr Vijaykumar Gawali 2020-10-16
BET-A; ACTIV-5/BET study: Big Effect Trial (BET-A) for the Treatment of COVID-19 Coronavirus disease 19 infection remdesivir plus risankizumab COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, IL-23 antagonist, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Allergy and Infectious Diseases National Institutes of Health US 2020-10-14 2021-07-01 20-0013A, BET-A, ACTIV-5/BET study, NCT04583956 Phase 2 Clinical Recruiting 10 8 Months 200 20-0013 Central Contact 2020-10-20
DYSPO: Photoplethysmographic Scaling of Dyspnea Coronavirus disease 19 infection, Dyspnea, Respiratory failure ECG alone, Pulse oximeter alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Institutul de Urgenta pentru Boli Cardiovasculare Prof.Dr. C.C. Iliescu Romania 2020-10-01 2021-07-30 18751, DYSPNOEA - SPO2 CURVE STUDY, DYSPO, NCT04582838 Phase Not Applicable Recruiting 2 9 Months 60 Balan Cosmin, Consultant, Balan Ion Cosmin, Cristian Cobilinschi, Consultant, Serban I Bubenek Turconi, Professor 2020-10-14
Differential Expression of Cytokines, Transcriptome and miRNA in Coronavirus Disease 2019 (COVID-19) Egyptian's Patients Coronavirus disease 19 infection C-reactive protein test alone, D-dimer test alone, PCR test alone, complete blood count test alone, cytokine profiling alone, differential leukocyte test alone, ferritin test alone, miRNA analysis alone, transcriptome analysis alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tanta University Egypt 2020-10-04 2022-10-03 CTM_COVID-19, NCT04583566 Phase Not Applicable Recruiting 2 24 Months 40 Mohammed Eid, Doctor, Mohammed El Shanshoury, Professor, Mohammed Hanteera, Professor 2020-10-14
KNC19: Knust COVID-19 Clinical Trial Coronavirus disease 19 infection Nibima alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) kwame Nkrumah University of Science and Technology Ghana 2020-12-01 2021-01-29 KNC19, PACTR202010690466874 Phase 2 Clinical Not yet recruiting 1 1 Month 20 Ellis Owusu Dabo, Mohamed Mutocheluh 2020-10-14
Send-In Sample Collection for Comprehensive Analyses of Innate and Adaptive Immune Responses During Acute COVID-19 and Convalescence Coronavirus disease 19 infection Healthy volunteers accepted, Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Allergy and Infectious Diseases National Institutes of Health Clinical Center US 2020-10-23 2025-08-31 000044-I, 10000044, NCT04582903 Phase Not Applicable Recruiting 1 58 Months 500 Helen C Su, M.D., Helen Su, M.D. Ph. D, Sandra M Maxwell, R.N. 2020-10-21
Comparison of the effectiveness of two treatment regimens in patients with COVID-19 Coronavirus disease 19 infection Sovodak (Faravan Rojan Mohaghegh Darou) plus hydroxychloroquine (Iran Daru) Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Iran University of Medical Sciences Iran 2020-07-19 IR.IUMS.FMD.REC.1399.407, IRCT20200328046885N1 Phase 2 Clinical No longer recruiting 2 300 Dr Abbas Motevalian, Mahin Jamshidi Makiani 2020-10-15
NICORISCOVID: Tobacco and Nicotine Consumption and the Risk of Acquisition of Coronavirus Disease 2019 (COVID-19) Coronavirus disease 19 infection RT-PCR alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-10-12 2020-12-01 APHP200663, NCT04583761, NICORISCOVID Phase Not Applicable Not yet recruiting 1 1 Month 1000 Marina Karmochkine, MD 2020-10-15
Evaluate the Safety, Tolerability, Pharmacodynamics, Pharmacokinetics, and Immunogenicity of HLX-71 (Recombinant Human Angiotensin-converting Enzyme 2-Fc Fusion Protein for COVID-19) in Healthy Adult Subjects Coronavirus disease 19 infection HLX-71 alone Angiotensin converting enzyme 2 inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hengenix Biotech Inc US 2020-11-30 2021-05-31 HLX71-001US-253460, NCT04583228 Phase 1 Clinical Not yet recruiting 1 6 Months 40 Esther Yoon, MD, Jinyun Bai 2020-10-15
Physical Activity Levels of Hypertensive and Healthy Individuals Under Social Isolation During the COVID-19 Pandemic Coronavirus disease 19 infection, Hypertension Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hacettepe University Turkey 2020-06-01 2021-02-01 GO 20/610, NCT04583345 Phase Not Applicable Recruiting 1 8 Months 32 Beyza Nur Karaduz, MSc, Ebru Calik Kutukcu, PhD, Naciye Vardar Yagli, PhD, S. Lale Tokgozoglu, Professor, Yusuf Ziya Sener, MD 2020-10-20
NICOVID-PREV: Efficacy of Nicotine in Preventing COVID-19 Infection in Caregivers Coronavirus disease 19 infection Nicotine patch (Nicopatchlib) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-10-31 2021-10-31 2020-003722-23, APHP200538, NCT04583410, NICOVID-PREV Phase 3 Clinical Not yet recruiting 2 12 Months 1633 Florence TUBACH, MD, Guylaine LABRO, MD, Raphael GAILLARD, MD, Zahir AMOURA, MD 2020-10-20
AIDED: Acute Kidney Injury in Covid-19 Coronavirus disease 19 infection, Renal injury Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospitals Of Derby and Burton NHS Foundation Trust UK 2020-10-31 2022-09-30 AIDED, NCT04583293, UHDB/2020/076 Phase Not Applicable Not yet recruiting 1 23 Months 220 Maarten W Taal, Professor, Nitin V Kolhe, Doctor 2020-10-14
DISCOVER: The Salivary Raman COVID-19 Fingerprint Coronavirus disease 19 infection Aramis Raman microscope (Horiba Jobin-Yvon) alone, Raman spectroscopy alone, portable Raman spectrometer alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fondazione Don Carlo Gnocchi - Onlus Italy 2020-06-01 2021-06-01 DISCOVER, FDG_SALIVACOVID01, NCT04583306 Phase Not Applicable Recruiting 2 12 Months 120 Cristiano Carlomagno, PhD, Jorge Navarro, MD, Luca C Bianchi, MD, Marzia Bedoni, PhD, Paolo I Banfi, MD 2020-10-14
Evaluation of the efficacy and safety of Atazanavir/Ritonavir plus Hydroxychloroquine regimen in patients with moderate COVID-19 Coronavirus disease 19 infection, Viral pneumonia atazanavir sulfate + ritonavir (HIV infection), Mylan Laboratories plus hydroxychloroquine HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Mazandaran University of Medical Sciences Iran 2020-08-22 IR.MAZUMS.REC.1399.602, IRCT20200328046886N2 Phase 3 Clinical Recruiting 1 120 Hamideh Abbaspour Kasgari, Hamideh Abbaspour kasgari, Research and technology department 2020-10-14
A study to analyze results of COVID-19 testing in anesthesia procedures using the polymerase chain reaction (PCR) Coronavirus disease 19 infection polymerase chain reaction (PCR) test alone American Society of Anesthesiologists US Phase Not Applicable Status not specified 1 1033 2020-10-18
A clinical study of Reveal 35C in the detection of pneumonia (including COVID-19) Coronavirus disease 19 infection, Viral pneumonia Reveal 35C alone KA Imaging Inc Canada Phase Not Applicable Status not specified 1 2020-10-13
Association of calcium channel blocker use with COVID-19 clinical outcome: a metaanalysis Cardiovascular disease, Coronavirus disease 19 infection calcium channel blocker therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitas Airlangga Asia 2020-10-11 UMIN000042076 Phase Not Applicable Recruiting 0 1000 Eka Mulia, Mochamad Yusuf 2020-10-14
Effectiveness of favipiravir in comparison with tenofovir alafenamid in patients with COVID-19 Coronavirus disease 19 infection favipiravir (Nafas farmed Co) alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ardabil University of Medical Sciences Iran 2020-09-20 IR.ARUMS.REC.1399.310, IRCT20150808023559N23 Phase 2 Clinical Recruiting 1 100 Dr Farhad Pourfarzi, Somaieh Matin 2020-10-14
A Global, Phase IIb/III Clinical Trial to Assess the Effect of CV-07050101 in Patients With Coronavirus Disease 19 Infection Coronavirus disease 19 infection SARS-CoV-2 mRNA vaccine (COVID-19), CureVac alone COVID19 Spike glycoprotein modulator CureVac AG 2020-12-31 Phase 2/Phase 3 Clinical Planned 0 30000 2020-10-13
COVID-19 Watch + COVID-19 Pulse Coronavirus disease 19 infection COVID Watch alone, PCORI Pulse alone, automated text-messaging program alone, telemedicine nurse-led care alone, triage protocol alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Pennsylvania 2020-10-21 2021-10-31 844043, NCT04581863 Phase Not Applicable Not yet recruiting 0 12 Months 850 Dina Abdel-Rahman, BS, Jessie Hemmons, MS 2020-10-14
Effect of Beta-interferon and methylprednisolone in COVID-19 Coronavirus disease 19 infection Variable regimens including Keltra , beta-interferon , hydroxychloroquine , methylprednisolone , naproxen Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shahid Sadoughi University of Medical Sciences and Health Services Iran 2020-05-04 IR.SSU.REC.1399.040, IRCT20200825048514N1 Phase 3 Clinical No longer recruiting 1 60 Fatemeh sadat Aghaei meybodi, Masoud Mirzaei 2020-10-14
A Phase I/II Study to Assess the Safety, Tolerability and Pharmacokinetics of NGM-621 in Healthy Subjects, and to Assess the Safety, PK and Efficacy in Subjects With Moderate to Severe ARDS Caused by COVID-19 Adult respiratory distress syndrome, Coronavirus disease 19 infection NGM-621 alone Complement C3 inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) NGM Biopharmaceuticals Inc 2020-10-31 2021-09-30 621-CP-102, NCT04582318 Phase 1/Phase 2 Clinical Not yet recruiting 0 11 Months 48 NGM Study Director 2020-10-14
Effect of Blood Transfusion in COVID-19 Coronavirus disease 19 infection packed cell alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Boushehr University of Medical Sciences Iran 2020-10-11 IR.BPUMS.REC.1399.108, IRCT20201003048904N1 Phase 2 Clinical Recruiting 1 40 Farhad Abbasi, Farhad abbasi, Gholamreza khamisipour, Negar Changizi 2020-10-13
Proportional Open Ventilation (POV) Device and Its Efficacy in Managing Acute Respiratory Failure in COVID-19 Patients Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure Life2000 Ventilator alone, high-flow nasal cannula therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hill-Rom Holdings Inc US 2020-08-28 2020-10-31 CR-RR-2020-004, NCT04581161 Phase Not Applicable Recruiting 1 2 Months 10 Jonathan Shelver, MD, Malia Remackel, Marissa Peterson 2020-10-13
Comparison of tocilizumab versus itolizumab in covid-19 patient Coronavirus disease 19 infection tocilizumab alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) All India Institute of Medical Sciences Patna India 2020-10-19 CTRI/2020/10/028325 Phase 2 Clinical Not yet recruiting 1 50 Dr Poonam kumari 2020-10-20
Study to Investigate Long-term Pulmonary and Extrapulmonary Effects of COVID-19 Coronavirus disease 19 infection, Lung disease Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Inselspital, Berne Switzerland 2020-05-01 2023-06-01 2020-00799, NCT04581135 Phase Not Applicable Recruiting 9 37 Months 500 Christian Clarenbach, PD, Christian Garzoni, PD, Christophe von Garnier, Prof., Kurt De Jaegere, Manuela Funke-Chambour, MD, Manuela Funke-Chambour, PD, Marco Mancinetti, MD, Martin Brutsche, Prof., Paola Gasche Soccal, Prof., Pierre-Olivier Bridevaux, Prof., Sebastian R. Ott, PD 2020-10-13
COVID-IYON: Study Examining Data Pertaining to Clinical Outcomes and Organizational Responses to the 2020 SARS-CoV-2 Pandemic Cancer, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cancer Trials Ireland Ireland 2020-04-29 2021-06-30 COVID-IYON, CTRIAL-IE 20-01, NCT04581070 Phase Not Applicable Recruiting 11 14 Months 300 Dr. Andrew Hodgson, Dr. Anne Fortune, Dr. Derville O'Shea, Dr. Ezzat ElHassadi, Dr. Gerard Crotty, Dr. Janusz Krawczyk, Dr. Larry Bacon, Dr. Liam Smyth, Dr. Paula Calvert, Dr. Ruth Clifford, Dr. Ruth Morrell, Dr. Silvie Blazkova, Dr. Sinéad Cuffe, Dr. Siobhan Glavey, Prof. Bryan Hennessy, Prof. Cathy Kelly, Prof. Helen Enright, Prof. Janice Walshe, Prof. Linda Coate, Prof. Roisin Connolly 2020-10-14
An Experiment to Evaluate the Safety of agenT-797 in COVID-19 Patients With Severe Difficulty Breathing Coronavirus disease 19 infection, Respiratory distress syndrome agenT-797 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) AgenTus Therapeutics Inc Agenus Inc US 2020-09-21 2021-10-15 C-1300-01, NCT04582201 Phase 1 Clinical Recruiting 1 12 Months 55 Agenus, Inc. Clinical Trial Information, Koen Van Besien, MD, Koen Van Besien, MD, PhD, Medical Director 2020-10-13
Assessment of memory cells response to Mycobacterium Indicus Pranii vaccination Coronavirus disease 19 infection, Mycobacterium infection Mycobacterium Indicus Pranii (MIP) Vaccine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Manashi Chakrabarti Foundation India 2020-10-20 CTRI/2020/10/028326, NKPROTOCOL0401 Phase 2 Clinical Not yet recruiting 1 40 Dr Jyoti Rastogi, Dr Suparno Chakrabarti 2020-10-20
SARS-CoV2_KIDS: SARS-CoV2 Antibodies in Pediatric Patients (COVID-19) Coronavirus disease 19 infection Healthy volunteers accepted, Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) University of Erlangen-Nurnberg Medical School Germany 2020-10-05 2022-05-31 405_20 BC, NCT04581148, SARS-CoV2_KIDS Phase Not Applicable Not yet recruiting 1 19 Months 2000 Adrian Regensburger, MD, Antje Neubert, PhD 2020-10-13
AyurCoro3 Prophylaxis: Evaluation of use of , 'study medication' for prophylaxis in frontline health care workers involved in treating COVID-19 patients Coronavirus disease 19 infection AyurCoro-3 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bhaktivedanta Hospital and Research Institute India 2020-10-09 AyurCoro3 Prophylaxis, CTRI/2020/10/028324 Phase 2 Clinical Not yet recruiting 1 120 Dr Nanasaheb Memane, Dr Vijaykumar Gawali 2020-10-15
An Online-platform to Improve Patient-centered Care During the COVID-19 Pandemic: a GIMEMA Surveillance Program in Hematological Malignancies Coronavirus disease 19 infection, Hematological neoplasm IMEMA-ALLIANCE Platform online monitoring system alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gruppo Italiano Malattie EMatologiche dell'Adulto 2020-10-31 2024-10-31 GIMEMA-ALLIANCE PLATFORM, NCT04581187 Phase Not Applicable Not yet recruiting 0 48 Months 400 2020-10-13
Impact of the COVID-19 pandemic on graduating dental interns: A student’s perspective Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs) Manipal College of Dental Sciences India 2020-10-21 CTRI/2020/10/028296 Phase Not Applicable Not yet recruiting 1 400 Dr Mathangi Kumar 2020-10-13
COSMIC-19: Continuous Signs Monitoring In Covid-19 Patients Coronavirus disease 19 infection Isansys Patient Status Engine alone, continuous vital sign monitoring alone, machine learning artificial intelligence technology alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The Christie NHS Foundation Trust Aptus Clinical Ltd, Manchester University NHS Foundation Trust, Zenzium Ltd UK 2020-07-11 2021-02-01 CFTSP187, COSMIC-19, NCT04581031 Phase Not Applicable Recruiting 2 6 Months 60 Anthony Wilson, Fiona Thistlethwaite, Fiona Thistlethwaite, MB BChir PhD 2020-10-14
Analysis of the SARS-CoV-2 specific immune response in persons with SARS-CoV-2 infection (COVID-19) Coronavirus disease 19 infection Healthy volunteers accepted University of Homburg Bethanien Krankenhaus gGmbH, Universitat des Saarlandes Germany 2020-10-15 76/20, DRKS00023086 Phase Not Applicable Not yet recruiting 2 190 Martina Sester, Simon Herkenrath 2020-10-13
Clinical Trial For SARS-CoV-2 Vaccine (COVID-19) Coronavirus disease 19 infection CoronaVac alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Sinovac Biotech Ltd Turkey 2020-09-14 2021-04-15 9026-ASI, NCT04582344 Phase 3 Clinical Recruiting 24 7 Months 13000 Ali Mert, Prof., Alpay Azap, Prof., Assoc. Prof., Aydın Yılmaz, Prof., Emin Halis Akalın, Prof., Fatma Şebnem Erdinç, Prof., Gülgün Dilek Arman, Prof., Gürdal Yılmaz, Prof., Hatice Rahmet Güner, Prof., Hüsnü Pullukçu, Prof., Murat Akova, Prof., Murat Akova, Professor, Mustafa Kemal Çelen, Prof., Sedat Altın, Prof., Serap Şimşek Yavuz, Prof., Serhat Ünal, Prof., Sıla Akhan, Prof., Taner Yıldırmak, Assoc. Prof., Taner Yıldırmak, Prof., Volkan Korten, Prof., Yaşar Bayındır, Prof., Yeşim Taşova, Prof., Ömer Fehmi Tabak, Prof., Özgür Batum, Specialist, İftihar Köksal, Prof., İlhami Çelik, Prof., İlkay Karaoğlan, Prof., Şükran Köse, Prof. 2020-10-13
Validation of Laboratory Techniques, Strategies, and Types of Samples for Epidemiological Control in the Covid-19 Pandemic Coronavirus disease 19 infection LAMP technique alone, Pool LAMP alone, Pool RT-PCR alone, RT-PCR alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) CUNY Hunter College Universidad Autonoma Juan Misael Saracho Bolivia 2020-10-08 2020-11-30 NCT04581083, PROY - UAJMS001/2020 Phase Not Applicable Recruiting 1 1 Month 30 Carmen Amanda Delagadillo Delgadillo, MD, Jimena Martinez, MD, Jorge Tejerina, Lic., Kenji Shoji, PhD, Lucia Alvarado Arnez, PhD, Paloma Rojas Saunero, MD, MSc, Rodrigo Arce Cardozo, Rodrigo Arce Cardozo, MD, MPH, Rodrigo Arce Cardozo, MD,MPH, Roxana Valdez Zamorano, Wilson Muriel Argollo, MD 2020-10-21
PHRUCov01: Trial of Triazavirin (TZV) for the Treatment of Mild to moderate COVID-19 Coronavirus disease 19 infection standard of care treatment alone, triazavirin alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Wits Health Consortium (Pty) Ltd Perinatal HIV Research Unit, PharmaCentrix (Pty) Ltd, University of the Witswatersrand South Africa 2020-09-08 2021-12-31 NCT04581915, PHRU COV01, PHRUCov01 Phase 2/Phase 3 Clinical Recruiting 1 15 Months 420 Fatima Mayat, Firdaus Nabeemeeah, MBBCh, Neil A Martinson, MBChB, Tumelo Moloantoa, MBChB 2020-10-20
A phase III, global. non-contact trial to assess CoronaVac in healthcare workers in Dhaka, Bangladesh Coronavirus disease 19 infection CoronaVac alone LSK Global Pharma Services Co Ltd Bangladesh Phase 3 Clinical Planned 1 4200 2020-10-12
CLASSIC: Perceptions of the Clinical and Psychosocial Impact of Covid-19 in Patients With Neuromuscular and Neurological Disorders Coronavirus disease 19 infection, Duchenne dystrophy, Neurological disease, Neuromuscular disease, Spinal muscular atrophy Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Royal Brompton & Harefield NHS Trust UK 2020-09-11 2020-12-17 286495, CLASSIC, NCT04581577 Phase Not Applicable Recruiting 1 3 Months 75 Anita K Simonds, MD MBBS, Anita Simonds, MBBS, Kinesh Patel, PhD, Lydia A Spurr, MBBS BMedSci, Lydia Spurr, MBBS, Martin R Cowie, MD MSc, Mary Morrell, PhD 2020-10-13
Oscillation and Lung Expansion Therapy in Patients With COVID-19 Coronavirus disease 19 infection MetaNeb System alone, oscillation and lung expansion (OLE) therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hill-Rom Holdings Inc Emory University, Northwestern University US 2020-09-28 2021-01-01 CR-RR-2020-002, NCT04582214 Phase Not Applicable Recruiting 2 3 Months 30 Brian Becker, RT, Colin Swenson, MD, Elizabeth Cox, Lindsay Downing, MPH, Lisa Wolfe, MD, Phill Cooper 2020-10-13
Coro-Buddy: Buddy) Prevalence of Antibodies Against SARS-CoV-2 Virus That Causes COVID-19 in Tubingen Children Coronavirus disease 19 infection Healthy volunteers accepted, Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Tubingen Germany 2020-07-02 2021-12-31 CORO-BUDDY, Coro-Buddy, NCT04581889 Phase Not Applicable Recruiting 1 17 Months 2380 Andrea Kreidenweiss, Dr., Jana Held, Dr, Jana Held, Dr., Rolf Fendel, Dr., Yudi Tatiana Röckl-Pinilla, Dr. 2020-10-15
PK and Safety of Remdesivir for Treatment of COVID-19 in Pregnant and Non-Pregnant Women in the US Coronavirus disease 19 infection remdesivir alone COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) International Maternal Pediatric Adolescent AIDS Clinical Trials Group Puerto Rico, US 2020-10-15 2022-01-15 DAIDS STUDY ID 38746, IMPAACT 2032, NCT04582266 Phase Not Applicable Not yet recruiting 17 15 Months 40 Adriana Drada, FMD, CCRP, Aleisha Collinson-Streng, RN, BSN, Alice Stek, MD, Allison Agwu, MD, Barsha Chakraborty, BS, Brookie Best, PharmD, MAS, Christy Beneri, DO, Debra McLaud, RN, Diana Clarke, PharmD, Elizabeth Greene, MPH, Ellen Chadwick, MD, Ellen Cooper, MD, MPH, Gwendolyn Scott, MD, Irma L. Febo Rodriguez, M.D., Jaime Deville, MD, Katherine Knapp, MD, Kathleen George, MPH, LaTeshia Thomas-Seaton, Lourdes Topete, RN, Margaret Sanders, MPH, Mariam Aziz, MD, Mark Mirochnick, MD, Martina Badell, MD, Mary Paul, MD, Maureen McNichols, MSN, CCRP, Megan Loughran, Michele Carter, BS, RN, Mobeen Rathore, MD, Nina Sublette, PhD, APRN-BC, Ruth E. Santos, RN, MPH, BSN, Saniyyah Mahmoudi, ARNP, Shelley Buschur, RN, CNM, Stephen Spector, MD 2020-10-13
MEDyMAP: Mapping COVID-19 Spread in a Tertiary Hospital Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital General Universitario de Valencia University of Valencia Spain 2020-10-02 2021-06-15 COVID19-MAPA, MEDyMAP, NCT04581096 Phase Not Applicable Recruiting 1 8 Months 3000 Adina Iftimi, PhD, Carolina Romero García, PhD, Carolina S Romero Garcia, PhD, Carolina Soledad Romero Garcia 2020-10-13
A phase II clinical trial of CYP-001 for the treatment of respiratory distress associated with COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome mesenchymoangioblast-derived mesenchymal stem cell therapy (Cymerus, critical limb ischemia/graft versus host disease/asthma/diabetic foot ulcer), Cynata/FUJIFILM alone Cynata Therapeutics Ltd Phase 2 Clinical Planned 0 2020-10-12
Patients Reactions Towards Their Diagnosis as Having COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) ClinAmygate Egypt 2020-10-10 2020-11-15 NCT04581928, PR0020 Phase Not Applicable Not yet recruiting 1 1 Month 300 Emad R Issak, MD 2020-10-13
Impact of COVID-19 on Psoriasis Practice Coronavirus disease 19 infection, Psoriasis Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cairo University Egypt 2020-09-17 2020-10-31 KAPU2020 10, NCT04581044 Phase Not Applicable Recruiting 1 1 Month 150 Asmaa Abdelnaby, MD, Mohamed HM EL-Komy, MD, Mona El-Kalioby, MD 2020-10-13
A pivotal, randomized, double-blind study to evaluate CPI-006 in hospitalized COVID-19 patients Coronavirus disease 19 infection CPI-006 alone CD73 antagonist Corvus Pharmaceuticals Inc Phase Not Applicable Planned 0 2020-10-12
Evaluation of the effectiveness of intravenous infusion of human COVID-19 hyperimmune plasma with specific antibody titer in hospitalized patients with Covid-19: a randomized clinical trial Coronavirus disease 19 infection, Viral pneumonia human COVID-19 hyperimmune plasma alone, human COVID-19 hyperimmune plasma with antibody titer alone, routine treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tehran University of Medical Sciences Iran 2020-10-11 IR.TUMS.MEDICINE.REC.1399.436, IRCT20201004048922N1 Phase 3 Clinical Recruiting 1 75 Hamidreza Abtahi, Mohammadali Sahraeiyan, Mohammadreza Salehi, Parisa Kianpour 2020-10-13
Study of resistance to COVID-19 of medical staff (Pilot Study) Acute stress disorder, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Japanese Ministry of Health, Labor and Welfare Japan 2020-09-25 UMIN000042061 Phase Not Applicable Not yet recruiting 1 165 Hirayasu Kai, Kunihiro Yamagata 2020-10-14
Perception Of Dentists On Infection Control Measures During Novel Corona Virus (COVID-19) Pandemic Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Manipal College of Dental Sciences India 2020-10-25 CTRI/2020/10/028295 Phase Not Applicable Not yet recruiting 1 400 Dr Neetha Shenoy 2020-10-13
CoTroxCov Study: Cotrimoxazole in hospitalised patients with moderate to early-severe COVID-19 infection Coronavirus disease 19 infection cotrimoxazole alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ministry of Health and Family Welfare India 2020-10-26 CTRI/2020/10/028297, CoTroxCov Study, U1111-1259-2654 Phase 2 Clinical Not yet recruiting 1 200 Dr Santanu Kumar Tripathi 2020-10-14
COVID-19, Prediction Model, Prognosis Coronavirus disease 19 infection prediction model alone Hospital Sungai Buloh Malaysia 2020-10-15 2022-09-15 56523, NMRR-20-2149-56523 Phase Not Applicable Status not specified 1 23 Months 1500 DR THARMINI A/P RAVI, Dr Sharifah Khairul Atikah 2020-10-13
COVIDstroke: Effect of COVID-19 pandemic on stroke admission trend in Malaysia Coronavirus disease 19 infection, Stroke Sultanah Nur Zahirah Hospital Malaysia 2020-11-01 2021-03-31 1, 56595, COVIDstroke, NMRR-20-2148-56595 Phase Not Applicable Not yet recruiting 1 5 Months Mrs NORSIMA NAZIFAH SIDEK 2020-10-13
PoCoPoHo: Post COVID-19 Infection: Impact of Clinical Severity and Timeline on Functional Status, Symptomology and Serological Status Post-Hospitalization Coronavirus disease 19 infection Hospital Raja Permaisuri Bainun Malaysia 2020-10-01 2020-10-31 NMRR-20-2125-56457, PoCoPoHo Phase Not Applicable Status not specified 1 1 Month MOH CHENG KEAT 2020-10-13
Antibiotic-COVID-19 Coronavirus disease 19 infection antibiotics alone Hospital Raja Permaisuri Bainun Malaysia 2020-10-12 2020-11-17 56531, NMRR-20-2124-56531 Phase Not Applicable Status not specified 1 1 Month Dr Izzati Nadhirah Bt Mohamad 2020-10-20
Intranasal administration of recombinant human interferon alfa-2b as prophylaxis of SARS-CoV-2 infection. (COVID-19) Coronavirus disease 19 infection nasalferon alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Center for Genetic Engineering and Biotechnology Cuba 2020-10-12 2020-11-06 IG / IAGN / VS / 2001, RPCEC00000337 Phase 1/Phase 2 Clinical Not yet recruiting 1 80 Francisco Hernandez Bernal, Leader Josué Diaz 2020-10-13
A prospective study of CoVerity in the diagnosis of severe respiratory failure risk in patients with PCR-confirmed SARS-CoV-2 pneumonia Coronavirus disease 19 infection CoVerity COVID-19 Severity Test alone Inflammatix Inc Greece Phase Not Applicable Status not specified 1 97 2020-10-12
Understanding Immunity to the Flu Vaccine in COVID-19 Patients Coronavirus disease 19 infection flu vaccine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Stanford University National Institute of Allergy and Infectious Diseases US 2020-12-01 2022-12-01 5U19AI057229-17, IRB-58356, NCT04579588 Phase Not Applicable Not yet recruiting 1 24 Months 80 Hena Din, Kari Nadeau, MD, PhD 2020-10-12
Fostamatinib for Hospitalized Adults With COVID-19 Coronavirus disease 19 infection fostamatinib disodium alone, standard of care alone Syk tyrosine kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Heart Lung and Blood Institute National Institutes of Health Clinical Center US 2020-10-08 2020-12-15 000110-H, 10000110, NCT04579393 Phase 2 Clinical Recruiting 2 2 Months 60 Edwinia Battle, Jeffrey R Strich, M.D., Jennifer J Kyte, D.N.P. 2020-10-13
EPID CLUSTER: Study of COVID-19 Clusters in Pahang Coronavirus disease 19 infection Jabatan Kesihatan Negeri Pahang Malaysia 2020-10-06 2020-10-21 55739, EPID CLUSTER, NMRR-20-2162-55739 Phase Not Applicable Status not specified 1 Dr WAN ABDUL RAHIM B WAN MUHAMMAD 2020-10-12
SeCuRE Study: Social isolation, depression, anxiety and resilience among older adults in Klang Valley during the COVID-19 crisis Anxiety disorder, Coronavirus disease 19 infection, Depression Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Selayang Hospital Malaysia 2020-11-02 2022-01-03 55538, NMRR-20-2169-55538, SeCuRE Study Phase Not Applicable Not yet recruiting 2 14 Months Dr Zanariah Mat Saher, Dr. Nor Jannah Nasution Raduan 2020-10-12
CORONAVIT: Trial of Vitamin D to Reduce Risk and Severity of COVID-19 and Other Acute Respiratory Infections Coronavirus disease 19 infection, Respiratory tract infection vitamin D alone Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Queen Mary University of London Barts Charity, Pharma Nord ApS UK 2020-10-19 2021-06-30 289515, CORONAVIT, NCT04579640 Phase 3 Clinical Not yet recruiting 1 8 Months 5440 Adrian R Martineau, MD PhD, David A Jolliffe, PhD 2020-10-12
Assessment of COVID-19 in Tearfilm Coronavirus disease 19 infection biological sampling alone, biopsy alone, fluorescein angiography alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Vanderbilt University Medical Center US US 2020-10-09 2021-05-09 201127, NCT04579458 Phase Not Applicable Recruiting 1 7 Months 500 Sapna Gangaputra 2020-10-13
Repeat Testing for SARS-CoV-2 Coronavirus disease 19 infection RT-LAMP Assay alone, Saliva assay test alone Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Wisconsin-Madison National Institutes of Health US 2020-09-29 2021-09-30 2020-1142, 5P51OD011106-59, A536300, NCT04579549, PROTOCOL VERSION 8/17/2020, SMPH/PATHOL-LAB MED/ANAT PATH Phase Not Applicable Recruiting 1 12 Months 10000 David O'Connor, PhD 2020-10-14
Study on use of Homoeopathy Medicines in Treatment of Covid 19 cases Coronavirus disease 19 infection Homoeopathy medicine alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Ministry of Ayush India 2020-10-10 CTRI/2020/10/028233 Phase Not Applicable Not yet recruiting 1 60 Dr SUGATHAN N V 2020-10-14
REMPAR-EHPAD: Managerial and Environmental Risk for COVID 19 in French Long-Term Care Institutions Coronavirus disease 19 infection Rennes University Hospital France 2020-06-15 2020-09-01 35RC20_8898_REMPAR-EHPAD, NCT04579289, REMPAR-EHPAD Phase Not Applicable Completed 1 2 Months 230 Aline MD CORVOL 2020-10-14
COVITRA: Prevalence and Outcome of SARS-CoV-2 Infection and COVID-19 in Transplant Recipients Coronavirus disease 19 infection, Hematopoietic stem cell transplantation, Organ transplantation SARS-CoV-2 IgG test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitaire Ziekenhuizen Leuven Jessa Hospital, Katholieke Universiteit Leuven, Universiteit Hasselt, Ziekenhuis Oost-Limburg Belgium 2020-07-01 2021-12-31 COVITRA, NCT04579471, S64036 Phase Not Applicable Recruiting 1 18 Months 2000 Jef Verbeek, MD, Jef Verbeek, MD, PhD, Natalie Van den Ende, Natalie Vandenende 2020-10-12
Psychological effect of coronavirus disease 2019 on pregnant women Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs) All India Institute of Medical Sciences India 2020-10-14 CTRI/2020/10/028232 Phase Not Applicable Not yet recruiting 1 25 Dr Poonam Kumari 2020-10-12
Proof of Concept Study of Ketoji (Liquid) for its Effectiveness in Treatment and Management of COVID-19 Patients Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory tract infection Ketoji alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ruby Hall Clinic India 2020-10-12 BPLS/KTJ/2020, CTRI/2020/10/028231 Phase 2 Clinical Not yet recruiting 1 15 Dr Kapil G Zirpe, Ms Pranjal Ausekar 2020-10-15
Clinical trial of Pippali Rasayana and Nagaradi Kashaya Ghana Vati combination as an adjuvant treatment with ICMR guided medicines in Covid-19 positive mildly symptomatic cases Coronavirus disease 19 infection  ICMR directed therapy alone, Variable regimens including Nagaradi Kashaya Ghana Vati , Pippali Rasayana , Rasayana Kala , Vyanodana Kala Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) PAED'S Ayurved Rugnalaya and Sterling Multispeciality Hospital India CTRI/2020/10/028230 Phase 2 Clinical Not yet recruiting 1 60 Dr Medha Mahesh Joshi, DrYogita Abhijit Jamdade 2020-10-12
A first-in-human clinical trial of ivermectin (oral, COVID-19), MedinCell for COVID-19 Coronavirus disease 19 infection ivermectin (extended release/sc/BEPO, COVID-19), MedinCell alone MedinCell SA 2020-09-29 Phase Not Applicable Recruiting 0 2020-10-20
Corticosteroids in COVID-19 Coronavirus disease 19 infection, Viral pneumonia dexamethasone alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tehran University of Medical Sciences Iran 2020-09-26 IR.TUMS.MEDICINE.REC.1399.430, IRCT20100228003449N31 Phase 2/Phase 3 Clinical Recruiting 1 119 Hossein Khalili, Mohammad Ali Sahraian 2020-10-12
FACIAL HAIR: Facial Hair, PPE and COVID-19 Coronavirus disease 19 infection Healthy volunteers accepted Royal Cornwall Hospitals Trust UK 2020-05-14 2020-06-08 283609, FACIAL HAIR, NCT04579627 Phase Not Applicable Completed 1 358 2020-10-12
RECEDE: Regional COVID Epidemiology in England Coronavirus disease 19 infection, Renal injury Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospitals Of Derby and Burton NHS Foundation Trust UK 2020-11-01 2021-10-31 NCT04579562, RECEDE, UHDB/2020/075 Phase Not Applicable Not yet recruiting 1 12 Months 5000 Nitin V Kolhe, DM 2020-10-13
A study to know whether investigators can supervise cancer patients infected with COVID-19 from without admission in hospitals. Investigators will test how much helpful is a software called Datos health along with pulse oximeter and thermometer in this supervision by doctors Coronavirus disease 19 infection Datos Platform alone, pulse oximeter alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tata Memorial Hospital India 2020-10-13 CTRI/2020/10/028256 Phase Not Applicable Not yet recruiting 1 30 Dr Manju Sengar 2020-10-12
Psychological Impacts Of The COVID-19 Pandemic On Medical Students In India: A Web-Based Cross-Sectional Study Coronavirus disease 19 infection Young Adults (18-44 yrs) Sri Ramachandra Institute of Higher Education and Research India 2020-10-10 CTRI/2020/10/028257 Phase Not Applicable Not yet recruiting 1 500 Dr S Natarajan, Ria Tyagi 2020-10-12
Feasibility study of a mobile device for the prevention of sepsis in patients with solid tumors after chemotherapy and patients with infectiose diseases (COVID-19) Coronavirus disease 19 infection, Respiratory tract infection, Sepsis VitalPatch alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitätsklinikum Frankfurt Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie HMS Analytical Software GmbH Germany 2019-08-02 DRKS00017593, FF136/2018 Phase Not Applicable Recruiting 1 50 Mate Knabe 2020-10-20
CAMMS: Inhibiting transmission of respiratory viruses Coronavirus disease 19 infection nutraceuticals alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) India 2020-11-01 CAMMS, CTRI/2020/10/028255 Phase 2 Clinical Not yet recruiting 2 200 Dr Suman Kapur, Dr Vibhor Tak 2020-10-12
PregCOVID: Retrospective Study of Pregnancy with COVID-19 Coronavirus disease 19 infection Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Dr TMA Pai Hospital India 2020-10-08 CTRI/2020/10/028254, PregCOVID Phase Not Applicable Not yet recruiting 1 44 Shashikala Bhat 2020-10-12
Correlation Between Thoracic Ultrasound and Thorax Computed Tomography Scores Coronavirus disease 19 infection, Viral pneumonia lung ultrasound (LUS) alone, thorax computed tomography (CT) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gaziosmanpasa Taksim Research and Education Hospital Turkey 2020-06-05 2020-09-05 AYŞEV, NCT04577235 Phase Not Applicable Completed 1 3 Months 29 Ayşe Vahapoglu, M.D 2020-10-12
Effect of CBT Intervention to Improve Sleep on Wellbeing, Dietary Intake and Food Preference Coronavirus disease 19 infection, Insomnia cognitive behavioral therapy alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Glasgow UK 2020-10-05 2021-06-01 200190177, NCT04576260 Phase Not Applicable Not yet recruiting 2 7 Months 40 Ayan Merchant, MSc, Ayan Merchant, MSc., Cindy Gray, PhD, Jason Gill, PhD, Stuart Gray, PhD 2020-10-13
An observational, single-center, cohort study to evaluate the association between treatment with colchicine and improved survival of adult hospitalized patients with COVID-19 pneumonia and acute respiratory distress syndrome Coronavirus disease 19 infection, Respiratory distress syndrome colchicine alone, dexamethasone alone, hydroxychloroquine alone, lopinavir + ritonavir alone, standard of care alone, Variable regimens including dexamethasone , hydroxychloroquine , lopinavir + ritonavir HIV protease inhibitor Italy Phase Not Applicable Status not specified 1 262 2020-10-12
Q-TIP: Comparison between certified swab systems (Copan eSwab) and commercially available cotton swabs ('Q-Tip') for the detection of multi-resistant pathogens (MRE) using rectal swabs Coronavirus disease 19 infection, Infectious disease Ebelin Q-Tip cotton swab alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) UniversitätsKlinikum Leipzig Germany 2020-09-20 327/20-ek, DRKS00023249, Q-TIP Phase Not Applicable Recruiting 1 600 Johannes Wiegand 2020-10-13
Corona CPR: Impact of personal protective equipment (PPE) during a simulated cardiac arrest in times of the COVID-19 pandemic Cardiac arrest, Coronavirus disease 19 infection FFP2 personal protective equipment use alone, simulated resuscitation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Arbeitsgemeinschaft Intensivmedizin e.V Germany 2020-09-20 2020-602-f-S, Corona CPR, DRKS00023184 Phase Not Applicable Recruiting 1 400 Stephan Marsch, Timur Sellmann 2020-10-12
Effect of spiritual care based on Ghalbe Salim on anxiety related to COVID-19 (corona phobia) Anxiety disorder, Coronavirus disease 19 infection, Phobia Ghalbe Salim model based spiritual program alone Female Iran 2020-05-23 2020-07-31 IR.LARUMS.REC.1399.001, IRCT20201003048905N1 Phase Not Applicable Completed 1 2 Months 14 Dr Behzad Rezaie, Zohreh Faramarzian 2020-10-09
Randomized, phase II clinical trial to evaluate safety and efficacy of the use of plasma from convalescent patients with the new coronavirus disease (COVID-19) for the experimental treatment of patients hospitalized in the centro medico naval 'cirujano mayor santiago tavara' Coronavirus disease 19 infection convalescent plasma alone, standard hospital treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) NAVY OF WAR OF PERU Peru 2020-09-07 CEMENA-20-01 Phase 2 Clinical Not yet recruiting 1 100 César José Suárez De Armero, José Martín Avilés Calderón, MARIO ORTIZ MONDRAGÓN, Max Grogl 2020-10-20
SALICOV: Evaluation of a Screening Program for SARS-CoV-2 Infection in the General Population Based on the Use of New Detection Approaches or for Diagnostic Orientation on Saliva Coronavirus disease 19 infection saliva sampling alone Assistance Publique Hopitaux de Paris France 2020-10-31 2021-06-30 2020-A02431-38, APHP200960, NCT04578509, SALICOV Phase Not Applicable Not yet recruiting 1 8 Months 2750 Jérôme Le Goff, Professor, LE GOFF Jérôme, Professor, Laure Choupeaux, Master, Solen Kernéis, Doctor, Solen Kernéis, MD, PhD 2020-10-12
SOGUGCOVID: Description of the Population With Genitourinary Tumors and COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Spanish Oncology Genito-Urinary Group Spain 2020-09-30 2021-10-31 NCT04578132, SOG-INM-2020-04, SOGUGCOVID Phase Not Applicable No longer recruiting 32 13 Months 250 Aránzazu González del Alba, M.D., Ph.D., Javier Puente, M.D., Ph.D., Miguel Ángel Climent, M.D., Ph.D., Natalia Vidal, M.D., Ph.D., Sergio Vázquez Estevez, M.D., Ph.D. 2020-10-12
TMPRSS2: Efficacy of Aerosol Combination Therapy of 13 Cis Retinoic Acid and Captopril for Treating Covid-19 Patients Via Indirect Inhibition of Transmembrane Protease, Serine 2 Coronavirus disease 19 infection 13 cis retinoic acid plus captopril ACE inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kafrelsheikh University Egypt 2020-11-30 2021-01-31 NCT04578236, SARS, TMPRSS2 Phase 2 Clinical Not yet recruiting 1 2 Months 360 Mahmoud Elkazzaz, B.Sc,M.Sc in Biochemistry 2020-10-12
Future Health Today: A cluster randomized controlled trial of quality improvement activities in general practice Cancer, Coronavirus disease 19 infection, End stage renal disease ECHO (Extension for Community Healthcare Outcomes) education alone, Future Health Today alone, cancer FHT module alone, chronic kidney disease (CKD) FHT module alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cancer Research UK, NHMRC Clinical Trials Centre, Paul Ramsay Foundation, University of Melbourne Australia 2020-12-18 2021-08-31 2056564, ACTRN12620000993998, ANZCTR380119, U1111-1254-1693 Phase Not Applicable Not yet recruiting 2 8 Months 8000 A/Prof Jo-Anne Manski-Nankervis 2020-10-17
A phase I clinical trial for inactivated SARS-CoV-2 Vaccine(Vero Cells) Coronavirus disease 19 infection COVID-19 vaccine (inactivated/Vero cells/intramuscular, SARS-CoV-2 infection), Shenzhen Kangtai Biological Products alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Jiangsu Province Centers for Disease Control and Prevention China 2020-10-07 2022-04-06 ChiCTR2000038804 Phase 1 Clinical Not yet recruiting 2 18 Months 180 Li Guifan, Pan Hongxing 2020-10-19
A clinical trial to test the effectiveness of thalidomide in reducing immune dysfunction in covid-19 disease Autoimmune disease, Coronavirus disease 19 infection thalidomide, Celgene alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ruby Hall Clinic India 2020-10-10 CTRI/2020/10/028253 Phase 2 Clinical Not yet recruiting 1 20 Dr Abhijit R Lodha 2020-10-09
A Study to Evaluate Efficacy of Selected Homoeopathic Medicines in Prevention of COVID-19 Coronavirus disease 19 infection Variable regimens including Arsenic album , Bryonia alba , Camphora Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Ministry of Ayush India 2020-10-15 CTRI/2020/10/028280 Phase Not Applicable Not yet recruiting 1 18000 Dr Meeta Gupta, Dr Raj K Manchanda 2020-10-09
Standard of care with homoeopathy as adjuvant in COVID19 Coronavirus disease 19 infection Homoeopathic medicine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences India 2020-10-12 CTRI/2020/10/028279 Phase Not Applicable Not yet recruiting 1 128 Dr Sushma Bhatnagar 2020-10-09
COVID-19 and children with congenital heart disease Congenital heart defect, Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) All India Institute of Medical Sciences India 2020-10-15 CTRI/2020/10/028251 Phase Not Applicable Not yet recruiting 33 50 Avinash Anantharaj, C S Muthukumaran, Dr Devaprasath, Dr Dharmendra Jain, Dr Gnanasambandan, Dr H ravi Ramamurthy, Dr Harmeet Singh Arora, Dr Jabaraj, Dr Jayashree Mishra, Dr Joseph Xavier, Dr K Sivakumar, Dr Kalyanasundaram, Dr M Jayranganath, Dr Mahesh K, Dr Manoj K Rohit, Dr P V Suresh, Dr Prabhatha Rashmi Murthy, Dr Prashant Mahawar, Dr Prashant Shah, Dr Rema Devi, Dr S Ramakrishnan, Dr Saileela, Dr Sanjay Khatri, Dr Smit Shrivastava, Dr Snehal Kulkarni, Dr Srinivas Lakshmivenkateshiah, Dr Swati Garekar, Edwin Francis, K M Krishnamoorthy, Kavya Mallikarjun, Prabhatha Rashmi Murthy, Rishi Sethi, Suresh Kumar 2020-10-09
The Knowledge, Attitude And Practices related to COVID-19 in Patients Presenting to Glaucoma Clinic and the Reasons for seeking Glaucoma care Coronavirus disease 19 infection, Glaucoma Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Aravind Eye Hospital - Pondicherry India 2020-10-12 CTRI/2020/10/028278 Phase Not Applicable Not yet recruiting 1 246 Dr AnnamalaiO, Dr Kavitha S, Dr Venkatesh R, Kalluri Satya Srividya 2020-10-09
A study to evaluate the effects of stem cells in patients with acute respiratory distress syndrome caused by pneumonia due to COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia Stempeucel alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Indian Council of Medical Research, Ministry of Health and Family Welfare India 2020-10-14 CTRI/2020/10/028250, ICMR/ARDS/20-21/001 Phase 2 Clinical Not yet recruiting 2 40 Dr Geeta Jotwani, Dr Manoj Kumar Panigrahi, Dr Pawan Kumar Gupta, Dr Sharat Damodar 2020-10-09
Effect of N95 mask on general condition and respiration of health care workers Coronavirus disease 19 infection N95 FFRs alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Hamdard Institute of Medical Sciences & Research (HIMSR) India 2020-10-19 CTRI/2020/10/028249 Phase Not Applicable Not yet recruiting 1 30 Sana Yasmin Hussain 2020-10-09
PPI: Stress-free after corona: a psychological help program Acute stress disorder, Coronavirus disease 19 infection, Psychiatric disorder behaviour modification technique based intervention alone, group-based face-to-face intervention alone, home based progressive muscle relaxation exercise alone, home based work sheet exercise alone, low-threshold online digital intervention alone, model deduction intervention alone, parenting strategies based intervention alone, psychoeducation alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Humboldt University of Berlin Germany 2020-09-01 2020-35, DRKS00023220, PPI Phase Not Applicable Recruiting 1 400 Ulrike Luken 2020-10-12
A study to assess the safety and effectiveness of Thymosin alpha-1 (Talpha1) used for the treatment of Moderate to severe COVID 19 Patients Coronavirus disease 19 infection Thymosin alpha alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gufic Bioscience Ltd India 2020-10-12 CTRI/2020/10/028277, GB_THY_001_20 Phase 3 Clinical Not yet recruiting 7 120 Dr Adarsh Shetty, Dr Arti Shah, Dr Dev Nath Jha, Dr Giridhar Patil, Dr Nirhali Sonali Chandrakant, Dr Rahul Ashok Darnule, Dr S K Sonkar, DrPrachee Milind Sathe, Mr Vairamuthu Ammaiyappan 2020-10-09
Chest Radiographic Findings of Adult Patients with Confirmed Coronavirus Disease 2019 (COVID-19) at Southern Philippines Medical Center Coronavirus disease 19 infection Southern Philippines Medical Center Philippines 2020-10-01 2020-12-15 PHRR201001-002988 Phase Not Applicable Recruiting 1 2 Months Maria Theresa T. Sanchez, MD, FPCR, Nalvic De Chavez 2020-10-09
A mHealth-based randomized controlled trial for improving mental health among people living with HIV during the COVID-19 outbreak Coronavirus disease 19 infection, Depression, HIV infection Articles and audios alone, WeChat-based Cognitive-Behavior and Stress Management course alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sun Yat-Sen University China 2020-10-15 2021-12-31 ChiCTR2000038866 Phase 0 Clinical Not yet recruiting 1 14 Months Yan Guo, Yu Zeng 2020-10-09
A Randomized, Double-blind, Placebo-controlled, Phase Ib/II Clinical Study to Evaluate the Preliminary Efficacy, Safety, Pharmacokinetic Profiles and Immunogenecity of JS-016 (Recombinant Human Anti-SARS-CoV-2 Monoclonal Antibody) Given as Intravenous Infusion in Participants with Mild and Moderate COVID-19 or of SARS-CoV-2 Asymptomatic Infection Coronavirus disease 19 infection etesevimab alone COVID19 Spike glycoprotein inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) PAREXEL Clinical Research, Shanghai Junshi Biosciences Co Ltd Philippines, Hong Kong, Ukraine, Singapore, Russian Federation, China 2020-09-30 2021-06-30 2020-CT0565, JS016-002-Ib/II, PHRR201001-002968 Phase 1/Phase 2 Clinical Not yet recruiting 7 9 Months 25 Chriziel Escaño, Fatima Gugova, Joel M. Santiaguel, MD, Maria Tarcela Gler, MD 2020-10-09
Does elective orthopaedic surgery in the pandemic era increase the risk of developing COVID-19? A combined analysis of retrospective and prospective study at a national tertiary hospital in Jakarta, Indonesia Coronavirus disease 19 infection, Viral pneumonia elective orthopedic surgery alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Indonesia Indonesia 2020-07-01 2020-08-31 ChiCTR2000038865 Phase Not Applicable No longer recruiting 1 2 Months Achmad Fauzi Kamal, I Wayan Arya Mahendra Karda 2020-10-12
Study on the risk perception, mental health, and behavioural responses of university students in Hong Kong in COVID-19 pandemic Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs) Chinese University of Hong Kong China 2020-10-19 2022-12-31 ChiCTR2000038864 Phase Not Applicable Not yet recruiting 1 26 Months 600 Queenie Hoi Wing WONG 2020-10-09
MALCOV: Malaria as a risk factor for COVID-19 in western Kenya and Burkina Faso Coronavirus disease 19 infection, Plasmodium infection pyronaridine +artesunate alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Liverpool School of Tropical Medicine, London School of Hygiene and Tropical Medicine Bill & Melinda Gates Foundation, Centers for Disease Control and Prevention, Groupe de Recherche Action en Santé (GRAS), Kenya Medical Research Institute Burkina Faso, Kenya 2021-01-11 MALCOV, PACTR202009642148520 Phase 2 Clinical Not yet recruiting 4 142 Chris Drakeley, Feiko ter Kuile, Hellen Barsosio, Simon Kariuki, Sodiomo Sirima 2020-10-09
The COVID-19 Community Engagement Study Coronavirus disease 19 infection community-owned risk communication intervention alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Makerere University Uganda 2020-10-05 PACTR202010729372570 Phase Not Applicable Not yet recruiting 1 800 Daniel Semakula, Nelson Sewankambo 2020-10-09
Interobserver variability and correlation with clinical outcomes in assessing COVID-19 related chest X-ray findings using the Brixia scoring system Coronavirus disease 19 infection Philippine General Hospital Philippines 2020-06-01 2020-09-28 PHRR200929-002986 Phase Not Applicable Completed 1 3 Months Jorrel Vincent Valdez, MD, FPCR, Michelle Regina Castillo, MD, Rovi Niño D. Samedra, MD, FPCR 2020-10-12
A case report on COVID-19 inflammatory syndrome with clinical features resembling Kawasaki disease Coronavirus disease 19 infection, Kawasaki disease IVIg alone, corticosteroids alone Male Columbia University, New York Presbyterian Hospital Phase Not Applicable Status not specified 0 2 2020-10-08
A phase III clinical study to assess two-dose regimen of JNJ-78436735 compared to placebo in the treatment of patients with SARS-CoV-2 infection Coronavirus disease 19 infection JNJ-78436735 alone Johnson & Johnson Phase 3 Clinical Planned 0 2020-10-19
RELEASE: Safety Infusion of Natural Killer Cells or Memory T-Cells as Adoptive Therapy in COVID-19 Pneumonia or Lymphopenia Coronavirus disease 19 infection, Lymphocytopenia, Viral pneumonia allogeneic NK cells alone, allogeneic T memory cells alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto de Investigación Hospital Universitario La Paz Asociación Instituto de Investigación Sanitaria BioCruces, Foundation for Health Research and Biomedical Valencia, Universidad Autonoma de Madrid, Universidad Miguel Hernandez de Elche Spain 2020-09-04 2021-03-31 NCT04578210, RELEASE, RELEASE Phase 1/Phase 2 Clinical Recruiting 1 6 Months 58 Antonio Pérez Martínez, Dr, Bernat Soria, Dr, Carlos Solano, Dr, Cristina Eguizabal, Dra, Víctor Alelú Hernández, Mr 2020-10-21
CARE+: Covid-19-associated research on hand eczema in the health sector – Part 1 Coronavirus disease 19 infection, Eczema health education training alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) iDerm an der Universität Osnabrück Germany 2020-11-08 Bo/34/2020, CARE+, DRKS00022957, DRKS00022958 Phase Not Applicable Not yet recruiting 1 260 Cara Symanzik 2020-10-09
Care +: Covid-19-associated research on hand eczema in the health sector – Part 2 Coronavirus disease 19 infection, Eczema DGUV skin washer alone, lipid-containing skin cleanser alone, standard cleanser alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) iDerm an der Universität Osnabrück Germany 2021-01-04 Bo/35/2020, Care +, DRKS00022957, DRKS00022958 Phase Not Applicable Not yet recruiting 1 35 Cara Symanzik 2020-10-09
A trial to evaluate a new COVID-19 rapid test for diagnosis of COVID-19 Coronavirus disease 19 infection COVID-19 rapid test alone Graphene Leaders Canada Inc Canada Phase Not Applicable Planned 1 2020-10-08
Trial to Study the Adjuvant Benefits of Quercetin Phytosome in Patients With COVID-19 Coronavirus disease 19 infection, Inflammatory disease, Respiratory disease, Respiratory distress syndrome, Respiratory failure Quercetin Phytosome plus remdesivir COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Liaquat University of Medical & Health Sciences Pakistan 2020-10-26 2021-04-25 LUMHS/REC/894, NCT04578158 Phase 2 Clinical Not yet recruiting 1 6 Months 200 Prof. Dr. Ikram Din Ujjan, Prof. Dr. Ikram Din Ujjan, MBBS, PhD, Prof. Dr. Saeed Khan 2020-10-20
A clinical trial of HOUND COVID-19 Breathalyzer, the world's first portable breathalyzer to capture SARS-CoV-2 virus in breath of human test subjects Coronavirus disease 19 infection HOUND COVID-19 BREATHALYZER alone Hound Labs Inc Phase Not Applicable Planned 0 2020-10-16
For covid-19 infection prevention measures in sport Coronavirus disease 19 infection exercise test alone, football helmets alone Healthy volunteers accepted, Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) St Marianna University School of Medicine Japan 2020-09-09 UMIN000042034 Phase Not Applicable Not yet recruiting 1 5 Hiroto Fujiya, Ryota Muroi 2020-10-09
NeuroCovid: A Study of Intensive Care-requiring Covid-19 Patients Cognitive disorder, Coronavirus disease 19 infection, Encephalitis Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Karolinska University Hospital Karolinska Institutet Sweden 2020-08-18 2022-11-30 DNR 2020-02760, NCT04578197, NeuroCovid Phase Not Applicable Recruiting 1 27 Months 100 Lars I Eriksson, Prof, Lars I Eriksson, Professor, Mia Kivipelto, Professor 2020-10-09
CEM: Melatonin in COVID-19 Coronavirus disease 19 infection, Inflammatory disease Variable regimens including acetaminophen , hydroxychloroquine , melatonin (Elite factory) , naproxen Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Tehran University of Medical Sciences Iran 2020-08-05 CEM, IR.TUMS.VCR.REC.1399.068, IRCT20200922048804N1 Phase 2 Clinical No longer recruiting 1 20 Nastaran Keyhanian, Zahra Alizadeh, ِDr. Mohammad Ali Sahraian 2020-10-12
Health Care Worker's Perception of Patient Safety During COVID-19 Pandemic Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidad Miguel Hernandez de Elche Pontificia Universidad Catolica De Chile, Universidad Antonio Nariño, Universidad Catolica Santiago de Guayaquil, Universidad de Santander, University of Sao Paulo Colombia, Ecuador, Chile, Spain 2020-09-01 2020-12-15 2020-09, NCT04576299 Phase Not Applicable No longer recruiting 4 3 Months 800 Jose J Mira, PhD 2020-10-11
NeuroCovid: The Norwegian Study of Nervous System Manifestations and Sequelae After COVID-19 Coronavirus disease 19 infection, Psychiatric disorder anti-viral drugs therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Oslo University Hospital Haukeland University Hospital, Helse Stavanger HF, Møre and Romsdal Hospital Trust, Nordlandssykehuset HF, Ostfold Hospital Trust, Sorlandet Hospital, St Olavs Hospital, Sykehuset Innlandet HF, Sykehuset Telemark, Sykehuset i Vestfold HF, University Hospital of North Norway, University Hospital, Akershus, Vestre Viken HF Norway 2020-09-01 2023-12-31 152727, NCT04576351, NeuroCovid Phase Not Applicable Recruiting 15 40 Months 150 Anette Huuse Farmen, MD PhD, Anne Hege Aamodt, MD PhD, Anne Hege Aamodt, MD, PhD, Barbara Ratajczak-Tretel, MD, Christian Samsonsen, MD PhD, Guttorm Eldøen, MD, Hanne F Harbo, MD,PhD,Prof, Heidi Øyen Flemmen, MD, Hilde K Ofte, MD PhD, Linn H Steffensen, MD PhD, MD,PhD,Prof, Marion Boldingh, MD PhD, Martin Kurz, MD PhD Prof, Martin Weisshaar, MD, Mette Bergum, MD, Mona S E Skjelland, MD PhD Prof, Randi Eikeland, MD, Tormod Fladby, MD PhD Prof, Trine H Popperud, MD PhD, Trine H Popperud, MD, PhD, Øyvind G Torkildsen, MD PhD Prof 2020-10-08
Study to Assess the Safety of Ascending Doses of UNI-911 Inhalation in Healthy Volunteers in Preparation for Evaluation in Adults With COVID-19 Coronavirus disease 19 infection niclosamide (COVID-19), UNION therapeutics/ Institut Pasteur Korea alone S phase kinase associated protein 2 inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) UNION therapeutics Denmark Technical University, The Danish National Advanced Technology Foundation, Trial Nation Denmark Denmark 2020-06-29 2020-12-31 NCT04576312, UNI911-101 Phase 1 Clinical Recruiting 3 6 Months 44 Mads Jellingsø, Torben Balchen, Ulf Sjöbring, MD, Wanja Nyoro 2020-10-09
A clinical study of novel and proprietary Aerosolized Delivery System (ADS) to aerosolize and deliver the KL4 surfactant noninvasively in COVID-19 patients that are at high risk of respiratory failure with an intent to avoid mechanical ventilation Coronavirus disease 19 infection Aerosurf (Aerosolized Delivery System) alone, lucinactant (aerosol), Windtree Therapeutics/ Esteve/ Lee's Pharmaceutical alone BMP10 gene inhibitor, BMP15 gene inhibitor Windtree Therapeutics Inc Phase Not Applicable Planned 0 2020-10-07
A study to fully assess the impact of KL4 surfactant on clinical endpoints such as time on mechanical ventilation, time in the ICU, mortality in COVID-19 patients who are intubated and mechanically ventilated for associated lung injury and ARDS Coronavirus disease 19 infection, Lung injury, Respiratory distress syndrome lucinactant (aerosol), Windtree Therapeutics/ Esteve/ Lee's Pharmaceutical alone BMP10 gene inhibitor, BMP15 gene inhibitor Windtree Therapeutics Inc Phase Not Applicable Status not specified 0 2020-10-09
ADVISe: Longitudinal Imaging of Microglial Activation in Different Clinical Variants of Alzheimer's Disease Alzheimers disease, Amnesia, Aphasia, Atrophy, Coronavirus disease 19 infection, Inflammatory disease 11C-ER-176 alone, Lumbar puncture alone, MK-6240-[18F] alone, MRI alone, PET scan alone, florbetaben (18F) alone Beta amyloid modulator Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Columbia University National Institute on Aging US 2020-11-01 2025-05-31 AAAS7810, ADVISe, NCT04576793, R01AG063888 Phase 2 Clinical Recruiting 1 55 Months 100 Aubrey S Johnson, William C Kreisl, MD, Zeljko Tomljanovic, MD 2020-10-09
The effect of cardiac massage training in patients with cardiac arrest with COVID-19 positioned in the ventral position Cardiac arrest, Coronavirus disease 19 infection, Respiratory disease cardiac massage training alone, chest compression alone, instructional video alone, prone position alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidade Federal de Sao Paulo - UNIFESP Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Brazil 2020-08-13 31510320.4.0000.5505, 4.016.959, RBR-2xxrrq, U111112573179 Phase Not Applicable No longer recruiting 1 1000 Comitê de Ética em Pesquisa, Elaine Peixoto Vieira Cavalcante, Juliana Lima Lopes 2020-10-12
The effect of chloroquine, hydroxychloroquine OR ivermectin in patients with severe manifestations of coronavirus Coronavirus disease 19 infection chloroquine difosfate alone, hydroxychloroquine sulfate alone, ivermectin alone Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidade Federal de Roraima Brazil 2020-05-01 30605020.7.0000.5302, 4.013.109, RBR-8h7q82 Phase 2 Clinical No longer recruiting 1 167 Allex Jardim Fonseca, ruy guilherme de souza silveira 2020-10-19
Sequelae of SAR-CoV2 infection on Quality of Life and Lung Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chulalongkorn University, Ratchadapiseksompotch Research Fund Thailand 2020-06-11 2021-06-30 TCTR20201006001 Phase Not Applicable Recruiting 1 12 Months 100 Worawan Sirichana 2020-10-09
High-Resolution Computed Tomographic (HRCT) Findings among Reverse Transcription Polymerase Chain Reaction (RT-PCR) Confirmed Coronavirus Disease 2019 (COVID-19) Adult Patients in Southern Philippines Medical Center Coronavirus disease 19 infection High-Resolution Computed Tomography alone Southern Philippines Medical Center Philippines PHRR201001-003007 Phase Not Applicable Not yet recruiting 1 Roman Aldo D. Reyes 2020-10-09
Trial for collection of blood samples from healed COVID-19 patients - research and development of in-vitro diagnostics Coronavirus disease 19 infection blood sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) R-Biopharm Ag Germany 2020-10-02 20-293, DRKS00022406 Phase Not Applicable Recruiting 1 50 Mr. Dr. med. Jan Heyckendorf, Mr. Markus Böhl 2020-10-09
Practices among anesthesiologists during COVID-19 pandemic; the risk and safety concerns Coronavirus disease 19 infection Southern Philippines Medical Center Philippines 2020-10-01 PHRR200929-002985 Phase Not Applicable Not yet recruiting 1 Alyssa Mae D. Albano 2020-10-07
Psychological Impact of Institutional Quarantine Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) PGIMER AND DR RML HOSPITAL India 2020-10-06 CTRI/2020/10/028194 Phase Not Applicable Not yet recruiting 1 100 Pragya Sharma 2020-10-08
Risk Factors and Computed Tomography Findings in COVID-19 Adult respiratory distress syndrome, Coronavirus disease 19 infection, Viral pneumonia Siemens 256-slice multidetector tomograph (SOMATOM) alone, chest computed tomography (CT) scan alone Instituto Nacional de Cardiologia Ignacio Chavez Mexico 2020-04-01 2020-10-01 20-1177, NCT04577105 Phase Not Applicable Completed 1 6 Months 233 Maria Elena Soto, MsC and PhD, Sergio Andres Criales Vera, MD 2020-10-08
Efficacy and Safety of Drug Combination Therapy of Isotretinoin and Some Antifungal Drugs as A Potential Aerosol Therapy for COVID-19: An Innovative Therapeutic Approach COVID-19 (Isotretinoin) Coronavirus disease 19 infection 13-cis-retinoic acid plus itraconazole Lanosterol-14 demethylase inhibitor Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kafrelsheikh University Egypt 2020-10-20 2020-11-20 ISOTRETINOIN, NCT04577378 Phase 2 Clinical Not yet recruiting 1 1 Month 45 Mahmoud Ramadan mohamed Elkazzaz, mahmoud Elkazzaz, B.Sc of biochemistry 2020-10-09
Factors associated with Job Satisfaction, Burnout, and Turnover Intention among Family and Community Medicine Resident Physicians during the COVID-19 pandemic: A Cross-Sectional Study Acute stress disorder, Coronavirus disease 19 infection, Psychiatric disorder Trinity University, Trinity University of Asia Philippines 2020-09-09 2021-03-09 PHRR201006-002996 Phase Not Applicable Recruiting 1 6 Months Aleph S. Doctora, Mel Anthony Acuavera 2020-10-19
A phase II/III, double-blind, placebo-controlled clinical trial to evaluate the safety, tolerability and efficacy of CardiolRx in hospitalized COVID-19 patients with a prior history of, or risk factors for, cardiovascular disease (CVD) Coronavirus disease 19 infection cannabidiol (nanoformulation/subcutaneous, heart failure), Cardiol Therapeutics alone Cardiol Therapeutics Inc US Phase 2/Phase 3 Clinical Not yet recruiting 1 422 Dr. Arvind Bhimaraj, Dr. Barry Trachtenberg, Dr. Carsten Tschöpe, Dr. Dennis McNamara, Dr. Leslie Cooper, Dr. Matthias Friedrich, Dr. Peter Liu, Dr. Wilson Tang 2020-10-07
Intravenous Tocilizumab in the Treatment of Patients with Severe and Critical COVID-19-related Pneumonia Coronavirus disease 19 infection, Viral pneumonia tocilizumab (intravenous), Roche/Chugai alone IL-6 receptor antagonist, IL-6 receptor modulator University of the Philippines Manila Philippine Council for Health Research and Development, Roche (Philippines), Inc Philippines 2020-07-16 2021-07-15 2020-CT0552, CTA-2020-20-08-31, PHRR201005-003010 Phase 2/Phase 3 Clinical Not yet recruiting 1 12 Months 98 Aileen David Wang, MD, Albert B. Albay, Jr., MD, Dr. Eric Jason Amante, Eric Jason Amante, MD, Fresthel Monica M. Climacosa, MD, PhD, John Carlo M. Malabad, John Carlo M. Malabad, MD, PhD, Marissa M. Alejandria, MD 2020-10-08
The Wellbeing of Surgical Residents at a Tertiary Level Government Hospital during the COVID-19 Pandemic Coronavirus disease 19 infection Southern Philippines Medical Center Philippines 2020-11-01 PHRR201001-002993 Phase Not Applicable Not yet recruiting 1 Ma. Theresa Monje, Philippe Michel Manalaysay 2020-10-07
A clinical trial to evaluate the effect of Wearable Technology to prevent COVID-19 complications and death for people recovering at home Coronavirus disease 19 infection Wearable Technology alone Albert Einstein College of Medicine, Montefiore Health System US Phase Not Applicable Status not specified 1 Jonathan D. Leff, M.D 2020-10-07
Risk factors for GI bleeding in COVID-19 patients with anti-coagulant use Coronavirus disease 19 infection, Gastrointestinal bleeding Chinese General Hospital and Medical Center Philippines 2020-09-30 PHRR201001-003002 Phase Not Applicable Not yet recruiting 1 Justin Ryan L. Tan, MD 2020-10-08
Outcomes of medical management of COVID-19 patients with GI bleeding Coronavirus disease 19 infection, Gastrointestinal bleeding medical management alone Chinese General Hospital and Medical Center Philippines 2020-10-01 2021-10-01 PHRR201001-003003 Phase Not Applicable Not yet recruiting 1 12 Months Justin Ryan L. Tan, MD 2020-10-08
Study of the use of ozone therapy adjunct to the treatment of Covid-19 infections Coronavirus disease 19 infection auto-hemotherapy alone, rectal ozone alone, the treatment established by the WHO alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Brazil 2020-07-05 30838820.2.1001.5704, 4.141.069, RBR-5v3k5d, U1111-1257-8184 Phase 3 Clinical Recruiting 1 150 Maria Emilia Gadelha Serra 2020-10-13
The effectiveness of online mindfulness training on mental health and quality of work life of nurses fighting on the frontlines against COVID-19 Acute stress disorder, Coronavirus disease 19 infection Mindfulness-based stress reduction training program alone Healthy volunteers accepted Oroumia University of Medical Sciences Iran 2020-09-22 IR.UMSU.REC.1399.105, IRCT20181203041832N1 Phase Not Applicable Recruiting 1 36 Firouzeh Sepehrianazar, Haedeh Feizipour, Iraj Mohebbi, Naser Gharebaghi 2020-10-08
Lessons-learned - developing a strategy for outpatient care during a pandemic in Baden-Württemberg, Germany. Patient characteristics and clinical course of infections with SARS-CoV-2 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Tubingen Ministerium Für Wissenschaft Forschung Und Kunst Baden-Württemberg Germany 2020-10-26 698/2020BO, DRKS00023069 Phase Not Applicable Not yet recruiting 1 2000 Christian Förster, Stefanie Joos 2020-10-08
CRISIS2: A Phase II Study Assessing the Safety and Antiviral Activity of Brequinar in SARS-CoV-2 Out-patients Coronavirus disease 19 infection brequinar alone, standard of care alone Dehydrogenase inhibitor, Dihydroorotate dehydrogenase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Clear Creek Bio, Inc 2020-10-15 2021-02-28 CCB-CRISIS-02, CRISIS2, NCT04575038 Phase 2 Clinical Not yet recruiting 0 4 Months 100 Barbara L Powers, PhD 2020-10-08
Celecoxib effects on COVID-19 patients Coronavirus disease 19 infection, Viral pneumonia celecoxib alone, routine therapy alone Cyclooxygenase 2 inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Zahedan University of Medical Sciences Iran 2020-09-22 IR.ZAUMS.REC.1399.197, IRCT20200907048644N1 Phase 1 Clinical Recruiting 2 60 Dr. Habib Ghaznavi, Dr. Mohammad Kazem Momeni, Dr. Nour Mohammad Bakhshani, Maliheh Metanat, Roghayeh Sheervalilou 2020-10-08
Efficacy and Safety of Molnupiravir (MK-4482) in Hospitalized Adult Participants With COVID-19 Coronavirus disease 19 infection molnupiravir alone RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Merck Sharp & Dohme Corp 2020-10-19 2021-10-18 2020-003367-26, 4482-001, MK-4482-001, NCT04575584 Phase 2/Phase 3 Clinical Not yet recruiting 0 12 Months 1300 Medical Director 2020-10-08
The possible beneficial role of the regular use of potent mouthwash solutions in the treatment of COVID-19 Coronavirus disease 19 infection chlorhexidine gluconate plus hydrogen peroxide Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hamad Medical Corp Qatar 2020-04-30 2020-11-20 ISRCTN10197987, MRC 05-106 Phase 2 Clinical No longer recruiting 2 6 Months 100 Dr Mukhtar 2020-10-08
New Educational Tool for FM Coronavirus disease 19 infection, Fibromyalgia, Pain PNE-explained alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hospital Vall D'Hebron University of South Australia Spain 2020-09-21 2021-10-10 NCT04571853, NEW EDUCATION TOOL Phase Not Applicable Recruiting 1 12 Months 300 Elena Granell, Lorimer Moseley, PhD, Mayte Serrat, MSc, Sara Marsall, PhD 2020-10-08
DeCODe: Detection of COVID-19 Decompensation Coronavirus disease 19 infection PinpointIQ solution (physIQ, Inc.) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) PhysIQ Inc National Cancer Institute, National Institute of Biomedical Imaging and Bioengineering, University of Illinois US 2020-10-05 2021-01-22 CTP-004, DeCODe, NCT04575532 Phase Not Applicable Recruiting 1 3 Months 400 Karen Larimer, PhD 2020-10-08
Remote Yoga Nidra for Anxiety and Sleep Anxiety disorder, Coronavirus disease 19 infection, Sleep disorder Yoga Nidra alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National College of Natural Medicine US 2020-04-15 2020-09-14 NCT04571593, NUNM Phase Not Applicable Completed 1 5 Months 74 Erica M Sharpe, PhD 2020-10-08
Clinical Study Spartan COVID-19 V2 System Coronavirus disease 19 infection Spartan COVID-19 v2 System alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Spartan Bioscience Inc Beaufort Canada, US 2020-10-31 2020-11-30 NCT04575168, VNV-00615 Phase Not Applicable Not yet recruiting 2 1 Month 100 2020-10-08
Effectiveness of VIRTUAL FIBROWALK STUDY Coronavirus disease 19 infection, Fibromyalgia Treatment as Usual (TAU) alone, VIRTUAL FIBROWALK alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hospital Vall D'Hebron Spain 2020-09-21 2021-11-10 NCT04571528, PR(AG)249/2020 Phase Not Applicable Recruiting 1 13 Months 300 Elena Granell, Mayte Serrat, MSc, Sara Marsal, PhD 2020-10-08
RESPECT: A Research Platform to Screen Healthcare Workers Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The University Health Network Canada 2020-04-16 2021-04-16 20-5289, NCT04574765, OZUHN-001, RESPECT Phase Not Applicable Recruiting 1 12 Months 100000 Amit M Oza, MD, Amit Oza, MD 2020-10-08
A study to assess safety and efficacy of PTX-COVID19-B for coronavirus infection Coronavirus disease 19 infection PTX-COVID19-B alone COVID19 Spike glycoprotein modulator University of Toronto Providence Therapeutics Holdings Inc Phase Not Applicable Planned 0 2020-10-06
Prevalence of COVID-19 Infection in a Cohort of Patients Infected by the HIV and Patients Taking PrEP Coronavirus disease 19 infection, HIV infection ELISA test alone, emtricitabine + tenofovir alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hôpital Européen Marseille France 2020-10-31 2022-04-30 2020-A02018-31, NCT04575545 Phase Not Applicable Not yet recruiting 1 18 Months 600 Myriam BENNANI, Patrick PHILIBERT 2020-10-07
HOPE_BRAZIL: A Trial of Hydroxychloroquine Plus Azithromycin in High-Risk COVID-19 Coronavirus disease 19 infection Reuquinol plus azithromycin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Latin American Cooperative Oncology Group Oncoclinicas Brazil 2020-06-30 HOPE_BRAZIL, LACOG 0220, NCT04575558 Phase 2 Clinical Terminated 7 2020-10-21
I-RAMIC: IRAK4 Inhibition in Treatment of COVID-19 With ARDS Coronavirus disease 19 infection, Inflammatory disease, Respiratory distress syndrome PF-06650833 alone, standard of care treatment alone, PF-06650833 plus ritonavir Cytochrome P450 3A4 inhibitor, HIV protease inhibitor, HIV-1 protease inhibitor, IRAK-4 protein kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Yale University Pfizer Inc US 2020-10-10 2021-03-31 2000028042, I-RAMIC, NCT04575610 Phase 2 Clinical Not yet recruiting 1 5 Months 68 Hyung Chun, MD, Kelly Borges, MS, BS 2020-10-08
Evaluation of the effect of nano-based inhalation solution to relieve shortness of breath in COVID-19 patients Coronavirus disease 19 infection, Dyspnea, Lung infection, Respiratory disease corticosteroid therapy alone, nebulizer mask alone, Variable regimens including colloidal silver nasal spray , dexamethasone , heparin , interferon beta-1a , interferon beta-1b , prednisolone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ahvaz University of Medical Sciences Iran 2020-08-22 IR.AJUMS.REC.1399.345, IRCT20190226042851N1 Phase 3 Clinical No longer recruiting 1 40 Fatemeh ahmadi, Hakim abiavy, Yousefi farid, mohamad badavi 2020-10-07
A trial to evaluate merimepodib monotherapy for the treatment of COVID-19 patients in the outpatient setting Coronavirus disease 19 infection merimepodib alone Inosine monophosphate dehydrogenase inhibitor Biosig Technologies Inc Phase Not Applicable Planned 0 2020-10-06
Efficacy and Safety of Molnupiravir (MK-4482) in Non-Hospitalized, Adult Participants With COVID-19 Coronavirus disease 19 infection molnupiravir alone RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Merck Sharp & Dohme Corp 2020-10-19 2021-10-14 2020-003368-24, 4482-002, MK-4482-002, NCT04575597 Phase 2/Phase 3 Clinical Not yet recruiting 0 11 Months 1450 Medical Director 2020-10-12
A Study of RLS-0071 in Patients With Acute Lung Injury Due to COVID-19 Pneumonia in Early Respiratory Failure Acute lung injury, Coronavirus disease 19 infection, Hypoxia, Inflammatory disease, Respiratory failure, Viral pneumonia PIC1-01 alone Complement C1s subcomponent inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) ReAlta Life Sciences Inc US 2020-10-31 2021-07-31 NCT04574869, RLS-0071-102 Phase 1 Clinical Not yet recruiting 1 9 Months 42 Efrain Garcia, MD, Kenji Cunnion, MD, MPH, Linda Dell, Naty Diaz, Rocio Navarro 2020-10-12
A new observational study finds patients in the hospital for COVID-19 have high levels of soluble urokinase receptor (suPAR) Coronavirus disease 19 infection University of Michigan Phase Not Applicable Status not specified 0 352 2020-10-07
A global, phase II/III study to assess safety and efficacy of COVID-19 vaccine Coronavirus disease 19 infection SCB-2019 alone COVID19 Spike glycoprotein modulator Clover Biopharmaceuticals Inc Coalition for Epidemic Preparedness Innovations 2020-12-31 Phase 2/Phase 3 Clinical Planned 0 2020-10-07
A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Safety, Tolerability, and Preliminary Efficacy of Intravenous Allogeneic Mesenchymal Stem Cells in Patients with Moderate to Severe Lung Injury due to COVID-19 Coronavirus disease 19 infection Allogeneic Mesenchymal Stem Cells, Stemedica Cell Technologies, Inc alone, standard treatment alone Stemedica Cell Technologies Inc Phase 2 Clinical Not yet recruiting 0 40 2020-10-06
MAVIPAN: My Life and the COVID-19 Pandemic Coronavirus disease 19 infection, Psychiatric disorder Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universite Laval CISSS de Chaudiere-Appalaches, Center for Interdisciplinary Research in Rehabilitation and Social Integration, Cervo Brain Research Centre, Réseau Provincial de Recherche en Adaptation-Réadaptation, Réseau québécois de recherche sur le vieillissement Canada 2020-04-29 2025-04-29 MAVIPAN, NCT04575571, TO BE ASSIGNED Phase Not Applicable Recruiting 1 60 Months 5000 Annie LeBlanc, PhD, Marie Baron, PhD 2020-10-07
Online multicomponent health intervention to support children with special education needs (SEN) and their families during COVID-19 pandemic Attention deficit hyperactivity disorder, Coronavirus disease 19 infection multi-component online health intervention alone Preschool Children (2-5 yrs), Children (6-12 yrs) Hong Kong Jockey Club China 2020-11-02 2021-12-02 ChiCTR2000038827 Phase Not Applicable Not yet recruiting 1 13 Months 1500 Prof. Eric Lee Kam Pui, Yuk Fai Ryan Ho 2020-10-07
HARD-COVID19: Health care workers exposed to COVID-19 Coronavirus disease 19 infection EMDR therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Tours INSERM 2020-10-15 2022-07-15 1-20-046 ID 48680, 2020-A01642-37, DR200160-HARD-COVID-19, HARD-COVID19, NCT04570202 Phase Not Applicable Not yet recruiting 0 21 Months 900 Wiebe de JONG, MSc, Wissam EL-HAGE, MD-PhD 2020-10-08
Covid19Reh: Cardiorespiratory Exercise & Chinese Medicine for Rehabilitation of Discharged Coronavirus Disease (COVID-19) Patients Coronavirus disease 19 infection, Pulmonary fibrosis cardiorespiratory exercise alone, modified Bai He Gu Jin Tang alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hong Kong Baptist University Chinese University of Hong Kong, Hong Kong Polytechnic University, The University of Hong Kong, University of California San Diego, University of South Wales, Yale University Hong Kong 2020-10-01 2023-06-30 Covid19Reh, HKCOVID19REHAB, NCT04572360 Phase Not Applicable Not yet recruiting 1 33 Months 172 Julien Baker, Ph.D, D.Sc, Linda Zhong, Linda Zhong, MD,PhD, Zhaoxiang Bian, Ph.D 2020-10-19
VPPIA: Virtual Parental Presence on Induction Anxiety disorder, Coronavirus disease 19 infection Use of Facetime with child and parents during induction alone Preschool Children (2-5 yrs), Children (6-12 yrs) Cincinnati Children's Hospital Medical Center Hospital for Sick Children US, Canada 2020-10-31 2022-12-31 2020-0371, NCT04574219, VPPIA Phase Not Applicable Not yet recruiting 2 26 Months 184 Clyde Matava, MD, Fahad Alam, MD, Kennth Goldschneider, MD, Kristie Geisler, BS, CCRP, Monica Caldeira-Kulbakas, Sawita Kanavitoon, Vanessa Olbrecht, MD 2020-10-08
KITCHEN: Keeping Infants Term - a Controlled High-risk Patient Enquiry Coronavirus disease 19 infection, Premature labor Multimodal intervention strategy alone Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) High Risk Pregnancy Center, Sera Prognostics Inc 2020-09-30 2025-06-30 1760 KITCHEN, KITCHEN, NCT04301518, SP019 KITCHEN Phase Not Applicable Not yet recruiting 0 57 Months 6500 Ashley Magnavita, MPH, Brian Iriye, MD, Gregory Massey 2020-10-19
Self-Breathe RCT for Chronic Breathlessness Asthma, Bronchiectasis, Cancer, Cardiac failure, Chronic obstructive pulmonary disease, Coronavirus disease 19 infection, Cystic fibrosis, Dyspnea, Interstitial lung disease, Liver failure, Renal failure, Sickle cell anemia SELF-BREATHE alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kings College Hospital NHS Trust King's College London 2020-12-03 2022-06-30 20/LO/1108, IRAS 285303, NCT04574050 Phase Not Applicable Not yet recruiting 0 18 Months 40 2020-10-08
Access to Chiropractic Care During the COVID-19 Healthcare Emergency in Spain Coronavirus disease 19 infection Chiropractic care (more than one visit) alone, Chiropractic care (one visit) alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Real Escorial-Maria Cristina University Center The University of Birmingham, Universite du Quebec a Trois-Rivieres Spain 2020-05-02 2020-05-27 CHIROCOVID19, NCT04573361 Phase Not Applicable Completed 1 723 Arantxa Ortega de Mues, PhD 2020-10-19
The Delays Among Covid-19 Cases in Samarahan Division, Sarawak Coronavirus disease 19 infection Malaysia 2020-10-01 2020-10-28 56468, NMRR-20-2122-56468 Phase Not Applicable Status not specified 1 Dr. Mohd Fahmi Bin Ismail 2020-10-08
Predicting Favorable Outcomes in Hospitalized Covid-19 Patients Coronavirus disease 19 infection EPIC risk score display alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) NYU Langone Health US 2020-05-15 2021-05-15 NCT04570488, PAU COVID19 RCT Phase Not Applicable Recruiting 1 12 Months 1200 Ashley Bagheri, MS, Jonathan Austrian, MD 2020-10-14
Online Education Intervention to Reduce Ageism Among Undergraduate Students Aging, Coronavirus disease 19 infection Online educational intervention to reduce ageism alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Mississippi 2020-09-28 2020-10-31 21X-046, NCT04570917 Phase Not Applicable Not yet recruiting 0 1 Month 121 Daniel Riche, Nadeeja Wijayatunga 2020-10-07
Mild Hypothermia for COVID-19 ARDS Coronavirus disease 19 infection, Respiratory distress syndrome Arctic Sun 5000 alone, hypothermia alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Northwell Health Inc US 2020-05-18 2020-12-31 NCT04570462, PROTOCOL 5.18.2020 APPROVED Phase Not Applicable Recruiting 1 7 Months 20 Efstathia A Mihelis, MBA, Pey-Jen Yu, Pey-Jen Yu, MD 2020-10-07
MICIn: Investigating the COVID-19 mucosal immunity of children in Indonesia Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Diponegoro University Indonesia 2020-05-01 2021-10-15 ISRCTN32891583, MICIN210920, MICIn Phase Not Applicable Not yet recruiting 1 17 Months 100 Mrs RizkeCiptaningtyas 2020-10-08
Safety and Efficacy of Trans-Sodium Crocetinate (TSC) in SARS-CoV-2 (COVID-19) Infected Subjects Coronavirus disease 19 infection, Hypoxia standard of care alone, trans sodium crocetinate (intravenous), Diffusion Pharmaceuticals alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Diffusion Pharmaceuticals LLC Romania 2020-09-10 2021-12-14 100-303, NCT04573322 Phase 1/Phase 2 Clinical Recruiting 1 15 Months 224 Adrian Streinu Cercel, MD, Anna Grace, MA, BSN, Harry N Cook, RPh/MBA 2020-10-07
Assessment of the effect of nanocurcumin supplement in patients with COVID-19 Coronavirus disease 19 infection, Lower respiratory tract infection, Upper respiratory tract infection nanocurcumin (Exir Nano Sina Company) alone, routine treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Tehran University of Medical Sciences Iran 2020-05-21 2020-12-20 IR.TUMS.VCR.REC.1399.28, IRCT20131125015536N13 Phase Not Applicable Recruiting 2 7 Months 48 Mohammad Javad Hossein Zadeh, Neda Alijani, Saied Reza Jamali Moghadam, Tehran University of Medical Sciences 2020-10-07
SeaCole: Evaluating a new model of rehabilitation for individuals recovering from COVID-19 Coronavirus disease 19 infection Rehabilitation Program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Nuffield Health Bournemouth UK 2020-04-06 2023-12-31 ISRCTN14707226, NHCRP001, SeaCole Phase Not Applicable Not yet recruiting 1 44 Months 500 Dr Benjamin Kelly 2020-10-08
KetoCOVID: Acute Effects of Oral Ketone Ester on Cardiac Function in Patients With COVID-19 Coronavirus disease 19 infection D-beta-hydroxybutyrate-(R)-1,3 butanediol monoester alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Steno Diabetes Center Odense Denmark 2020-10-01 2022-01-01 H-20021500, KetoCOVID, NCT04573764 Phase Not Applicable Not yet recruiting 1 15 Months 12 Jens Christian Laursen, MD, Peter Rossing, MD, Tor Biering-Sørensen, MD 2020-10-13
Treatment With Anti-SARS-CoV-2 Immunoglobulin In Patients With COVID-19 Coronavirus disease 19 infection anti-SARS-CoV-2 equine immunoglobulin (F(ab')2) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Instituto D'Or de Pesquisa 2020-12-01 2021-03-31 NCT04573855, PCL04/2020 Phase 1/Phase 2 Clinical Not yet recruiting 0 4 Months 41 2020-10-07
T Cells Response to SARS COV2 Peptides Coronavirus disease 19 infection ImmunoBiopsy metabolic activity method test (Savicell Diagnostic Ltd) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Savicell Diagnostic Ltd Israel 2020-10-10 2021-10-10 NCT04573348, PBMC _COVID 19 Phase Not Applicable Not yet recruiting 1 12 Months 400 Irena Shahar, BA, Shafrira Shai, PhD, Yochai Adir, Prof 2020-10-19
START: A Registry Study of COVID-19 Serological and Virological Testing to Accelerate Recovery and Transition Coronavirus disease 19 infection blood sampling alone, standard of care PCR test alone, standard of care clinical antibody test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Kentucky US 2020-05-15 2023-12-31 NCT04573634, PHARM-20-COVID19-START, START Phase Not Applicable Recruiting 1 43 Months 960 Derek Forster, MD, Jill Kolesar, PharmD, MS 2020-10-07
Mesenchymal Stem Cells for the Treatment of COVID-19 Coronavirus disease 19 infection mesenchymal stem cells (PrimePro) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) US 2020-04-24 2020-09-01 NCT04573270, PRO00043080 Phase 1 Clinical Completed 1 4 Months 40 Ernst R Von Schwarz, MD, PhD 2020-10-07
AEC COVID-19: National Study 'AEC COVID-19' Coronavirus disease 19 infection Surgical procedure alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospitales Universitarios Virgen del Rocío Spain 2020-03-01 2020-09-30 AEC COVID-19, AEC-COVID, NCT04573868 Phase Not Applicable Recruiting 1 7 Months 1000 Isaias Alarcón, MD PhD, Salvador Morales, Salvador Morales-Conde, Salvador Morales-Conde, MD PhD 2020-10-06
Coping with COVID Pandemic Coronavirus disease 19 infection Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bangladesh Health Professions Institute Bangladesh 2020-10-10 CTRI/2020/10/028196 Phase Not Applicable Not yet recruiting 1 3000 Asma Islam, K M Amran Hossain, Professor Md Obaidul Haque 2020-10-05
An observational, post-registrational study to evaluate the safety and efficacy of Avifavir in the treatment of patients with COVID-19 infection Coronavirus disease 19 infection favipiravir alone RNA polymerase inhibitor ChemRar Pharma Russian Direct Investment Fund Russian Federation Phase 4 Clinical Status not specified 1 940 2020-10-05
Clinical profile of neonates with suspected or proven SARS-CoV-2 infection Coronavirus disease 19 infection, Viral pneumonia Newborn Infants (up to 5 months) Government Medical College and Hospital,Chandigarh India 2020-10-12 CTRI/2020/10/028202 Phase Not Applicable Not yet recruiting 1 30 Deepak Chawla 2020-10-06
The role of Yogic breathing techniques in progression and recovery from COVID-19 Coronavirus disease 19 infection Yoga alone, longer duration breathing technique (LDBT) alone, short duration breathing technique (SDBT) alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ministry of Ayush India 2020-10-08 CTRI/2020/10/028195 Phase Not Applicable Not yet recruiting 1 72 Dr Akshay Anand 2020-10-06
The application of ultrasound-guided superior laryngeal nerve block used for alleviation of agitation after endotracheal intubation Agitation, Coronavirus disease 19 infection, Delirium, Viral pneumonia B-guided superior laryngeal nerve block alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Shengjing Hospital of China Medical University, The First Affiliated Hospital of Wenzhou Medical University China 2020-10-01 2021-06-30 ChiCTR2000038690 Phase 2 Clinical Not yet recruiting 2 9 Months 90 Jiehao Sun 2020-10-06
A survey to assess the effectiveness of Arsenicum Album 30C as a Prophylactic medicine against COVID-19 infection Coronavirus disease 19 infection Arsenicum Album 30C alone Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Homoeopathy India 2020-10-04 CTRI/2020/10/028192 Phase Not Applicable Not yet recruiting 1 15000 Dr Raja manoharan, Dr Selvan 2020-10-06
A study to examine the impact of chronic rhinosinusitis (CRS) on COVID-19 Coronavirus disease 19 infection, Sinusitis American Academy of Allergy Asthma and Immunology China Phase Not Applicable Status not specified 1 1172 2020-10-05
Effect of fluvoxamine on cytokine in COVID-19 patients Coronavirus disease 19 infection fluvoxamine (Abidi and Sobhan Pharmaceutical companies) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shaheed Beheshti Medical University Iran 2020-07-22 IR.SBMU.NRITLD.REC.1399.177, IRCT20131115015405N4 Phase 2/Phase 3 Clinical No longer recruiting 1 40 Mitra Safa 2020-10-06
Effect of Online Psycho-educational Interventions on Psychological Health of Patients with COVID-19 Acute stress disorder, Coronavirus disease 19 infection cognitive–behavioural techniques alone, mindfulness-based stress reduction techniques alone, multimedia psychoeducational content delivery though whatsApp alone, positive psychotherapy exercise alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shiraz University of Medical Sciences Iran 2020-03-10 2020-05-14 IR.SUMS.REC.1399.011, IRCT20201001048893N1 Phase Not Applicable Completed 2 2 Months 50 Abbas Rezaeianzadeh, Maryam Shaygan, Zahra Yazdani 2020-10-06
Diabetes Outcomes in COVID-19 Pandemic Coronavirus disease 19 infection, Insulin dependent diabetes, Non-insulin dependent diabetes Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) SERVICES INSTITUTE OF MEDICAL SCIENCES Pakistan 2020-06-01 2020-07-30 16102019, NCT04573335 Phase Not Applicable Completed 1 1 Month 1282 Saira Burney, MB, FRCP (Edin) 2020-10-06
Natural History of Post-Coronavirus Disease 19 Convalescence at the National Institutes of Health Chronic fatigue syndrome, Coronavirus disease 19 infection deep phenotyping alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Neurological Disorders and Stroke National Institutes of Health Clinical Center US 2020-10-23 2024-12-31 000089-N, 10000089, NCT04573062 Phase Not Applicable Recruiting 1 50 Months 1000 Angelique Gavin, Avindra Nath, M.D. 2020-10-21
Metabolic Cofactor Supplementation and Hydroxychloroquine Combination in Covid-19 Patients Coronavirus disease 19 infection hydroxychloroquine plus serine + L-carnitine tartrate + N-acetylcysteine + nicotinamide riboside Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Scandibio Therapeutics AB Alanya Alaaddin Keykubat University, Alkü Alanya Education and Research Hospital, Bakirkoy Dr. Sadi Konuk Research and Training Hospital, Bağcılar Training & Research Hospital, Canakkale Onsekiz Mart University, Dr.Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi, Istanbul Bakirkoy Maternity and Children Diseases Hospital, Istanbul Medipol University Hospital, Monitor CRO, Ümraniye Training & Research Hospital Turkey 2020-09-21 2021-03-31 COVID-19-MCS, NCT04573153 Phase 2/Phase 3 Clinical Recruiting 1 6 Months 400 Assoc. Prof. Levent DOĞANAY, MD 2020-10-19
Intervention to promote exercise behavior among older adults under the epidemic of COVID-19 Coronavirus disease 19 infection exercise alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kobe University Japan 2020-09-29 UMIN000041990 Phase Not Applicable No longer recruiting 1 300 Kazuhiro Harada 2020-10-19
A single-site, single-arm, open, Phase I Study to Evaluate the Safety, tolerability and pharmacokinetic of CD24-Fc in healthy adults Coronavirus disease 19 infection CD24-IgFc alone Signal transducer CD24 modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Beijing Ditan Hospital Capital Medical Universty China 2020-11-05 2021-08-05 ChiCTR2000038672 Phase 1 Clinical Not yet recruiting 1 9 Months 12 Longpin Yin, xianfeng Fang 2020-10-08
Effects of pulmonary rehabilitation in patients with COVID-19 Anxiety disorder, Coronavirus disease 19 infection, Depression, Dyspnea patient health information session alone, psychosocial support alone, pulmonary training rehabilitation alone, respiratory physiotherapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Klinik Bad Reichenhall Hochschule fur Gesundheit, Bochum, Ludwig-Maximilians University of Munich Germany 2020-04-28 20-326, DRKS00023180 Phase Not Applicable Recruiting 1 100 Konrad Schultz 2020-10-07
A clinical trial to focus on patients discharged after hospitalization for moderate to severe COVID-19 disease Coronavirus disease 19 infection National Institutes of Health Phase Not Applicable Planned 0 2020-10-05
A clinical trial to investigate whether anticoagulants or antithrombotic therapy can reduce life-threatening cardiovascular or pulmonary complications in newly diagnosed COVID-19 patients who do not require hospital admission Cardiovascular disease, Coronavirus disease 19 infection, Lung disease apixaban alone, aspirin alone Factor Xa antagonist National Institutes of Health Phase Not Applicable Recruiting 0 2020-10-05
A clinical trial to investigate the safety and effectiveness heparin to prevent clotting events and improve outcomes in hospitalized COVID-19 patients Coronavirus disease 19 infection heparin alone National Institutes of Health Phase Not Applicable Recruiting 0 2020-10-08
PROVID-CAPNETZ: Clinical, molecular and functional biomarkers for Prognosis, pathomechanisms and treatment strategies of COVID-19 (PROVID) Coronavirus disease 19 infection, Lung infection, Respiratory distress syndrome, Viral pneumonia biological sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hannover Medical School Charite Universitaetsmedizin Berlin, Deutsche Forschungsgemeinschaft (DFG), German Federal Ministry of Education and Research, University of Leipzig Germany 2020-10-15 DRKS00022871, Nr. 301-2008, PROVID-CAPNETZ Phase Not Applicable Not yet recruiting 15 400 Grit Barten-Neiner 2020-10-07
Efficacy and safety of chlorpromazine in the treatment of COVID-19 patients Coronavirus disease 19 infection atazanavir + ritonavir (Razavi Pharmaceutical Institute) plus chlorpromazine (Tehran Shimi Company) Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mazandaran University of Medical Sciences Iran 2020-10-31 IR.MAZUMS.REC.1399.617, IRCT20200913048708N1 Phase 2 Clinical Not yet recruiting 1 60 Dr Majid saeedi, Ebrahim Salehifar, Roya Ghasemian 2020-10-06
UVA Light Device to Treat COVID-19 Coronavirus disease 19 infection UV light therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cedars-Sinai Medical Center Aytu BioScience Inc US 2020-10-31 2020-12-31 883, NCT04572399 Phase Not Applicable Recruiting 1 2 Months 5 Cedars-Sinai, George Chaux, MD, Melissa Hampton 2020-10-09
Low Dose Lung Radiotherapy to Treat COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia external beam irradiation (0.5 Gy) alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Lancashire Teaching Hospitals NHS Trust National Institute for Health Research (NIHR) UK 2020-10-31 2021-04-30 285167, NCT04572412 Phase 1 Clinical Not yet recruiting 1 6 Months 13 Aashish Vyas, Dennis Hadjiyiannakis, Research Access 2020-10-06
COVIDTrach: A Cohort Study of Mechanically Ventilated COVID-19 Patients Undergoing Tracheostomy Coronavirus disease 19 infection tracheostomy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University College London UK 2020-08-01 2021-08-01 COVIDTrach, NCT04572438, Z6364106/0000/00/00 Phase Not Applicable Recruiting 1 12 Months 2500 Nick JI Hamilton, MBChB PhD, Nick JI Hamilton, MBcHB PhD 2020-10-07
A case study on verapamil as treatment for refractory status epilepticus secondary to PRES syndrome on a SARS-Cov-2 infected patient Brain disease, Coronavirus disease 19 infection, Status epilepticus ceftriaxone alone, dexamethasone alone, enoxaparin sodium alone, hydroxichloroquine alone, lacosamide alone, levetiracetam alone, lopinavir + ritonavir alone, valproate alone, verapamil alone Calcium channel inhibitor, Dihydropyrimidinase related protein 2 modulator, HIV protease inhibitor, Low molecular weight heparin, Sodium channel modulator Hospital Universitario Severo Ochoa Phase Not Applicable Status not specified 0 1 2020-10-07
FloR COVID-19: Pilot, Randomized, Controlled Trial: Fluoxetine to Reduce Hospitalization From COVID-19 Infection Coronavirus disease 19 infection fluoxetine hydrochloride alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Milton S. Hershey Medical Center US 2020-09-30 2021-10-31 00015598, FloR COVID-19, NCT04570449 Phase 0 Clinical Not yet recruiting 1 13 Months 40 Erika Saunders, MD 2020-10-06
PHYTO CoV: Evaluation of phytopharmaceuticals to improve the prognosis of Covid-19 disease in Togo Coronavirus disease 19 infection Biocire alone, Immunitum alone, Immutop alone, Secure alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Lomé Togo 2020-10-15 2021-04-30 PACTR202009483194545, PHYTO CoV Phase Not Applicable Not yet recruiting 3 6 Months 250 ADJOH Seraphin, DAGNRA Claver, EKOUEVI Didier Koumavi, Ihou WATEBA Mageste, KOKOU Kouami, SALOU Mounerou 2020-10-17
Dose Ranging Trial to Assess Safety and Immunogenicity of V-590 (COVID-19 Vaccine) in Healthy Adults Coronavirus disease 19 infection V-590 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) International AIDS Vaccine Initiative, Merck Sharp & Dohme Corp Merck & Co Inc 2020-10-22 2021-12-03 NCT04569786, V590-001 Phase 1 Clinical Not yet recruiting 0 13 Months 252 Medical Director 2020-10-09
COntinuation Versus Interruption of Immunomodulating Drugs in case of an Infectious disease in IMID patients (COVID I2 study), with special attention for COVID 19: a pragmatic, explorative randomized controlled trial Coronavirus disease 19 infection, Crohns disease, Inflammatory bowel disease, Psoriasis, Psoriatic arthritis, Rheumatoid arthritis, Spondylarthritis, Ulcerative colitis continued IA alone, standard of care alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sint Maartenskliniek Netherlands 2020-10-01 2022-10-01 NL73479.091.20, NL8922 Phase Not Applicable Planned 1 24 Months 2200 Merel Opdam 2020-10-08
DIEGO: A diet for the treatment of gout Coronavirus disease 19 infection, Gout usual care alone, whole food plant based diet counselling alone Reade Center for Rehabilitation and Rheumatology Netherlands 2020-09-15 2022-03-31 2020.405 - NL74142.029.20, DIEGO, NL8903 Phase Not Applicable Recruiting 1 18 Months 30 Wendy Walrabenstein 2020-10-09
A Study Looking at the Effectiveness, Immune Response and Safety of a COVID-19 Vaccine in Adults in the United Kingdom Coronavirus disease 19 infection Variable regimens including Matrix M , NVX-CoV2373 , seasonal influenza vaccine (quadrivalent, VLP), Novavax COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Novavax Inc UK Government UK 2020-09-28 2022-01-14 2019nCoV-302, 2020-004123-16, NCT04583995 Phase 3 Clinical Recruiting 18 15 Months 9000 Anna Heinen, CRF Team, Dr. Jane Minton, Eilidh Wright, Lakshmi Kumar, Nargis Hemat, Or go to www.bepartof.bradfordresearch.nhs.uk, Paul T Heath, MB BS FRACP FRCPCH, Paula Coventry, Prof. Jeremy Turner, Research Team, Roy Soiza, Seth Toback, MD, Sonia Serrano or Karen Bisnauthsing, St. Helier Site Team, Study Team, Trial Study Coordinator, www.bfwh.nhs.uk 2020-10-15
BCG-PRIME: Bacillu Calmette Geurin vaccination to prevent serious respiratory tract infection and covid-19 in vulnerable elderly - and apative randomized controlled trial Coronavirus disease 19 infection, Respiratory tract infection BCG vaccine alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitair Medisch Centrum Utrecht The Netherlands Organisation for Health Research and Development Netherlands 2020-08-27 2020-003470-47, 74730.041.20, BCG-PRIME, CoV-2_DDI Phase 4 Clinical Not yet recruiting 1 5200 2020-10-07
A Pilot study platform to investigate the pharmacodynamics on QT‐prolongation and pharmacokinetics after multiple dose administration of potential combination treatments for COVID-19 in healthy volunteers Coronavirus disease 19 infection lopinavir + ritonavir plus ribavirin HIV protease inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Medical University of Vienna Austria 2020-09-14 2020-002314-40, CoV-2_DDI Phase 2 Clinical Not yet recruiting 1 16 2020-10-05
A randomized, double-blind, placebo-controlled, adaptive-design study to assess the safety and efficacy of daily 200 mg fluvoxamine as add-on therapy to standard of care in moderate severity COVID-19 patients Coronavirus disease 19 infection fluvoxamine alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Sigmadrugs Kft Hungary 2020-09-17 2020-002299-11, SD-COVID19-01 Phase 2 Clinical Not yet recruiting 1 100 2020-10-08
Study on Traditional Chinese Medicine Intervention Program for the Sequela of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Jiexingjunzi granule alone, Qibei Fuzheng granule alone Beijing University of Chinese Medicine Beijing institute of Traditional Chinese Medicine China 2020-08-01 2021-08-01 ChiCTR2000038740 Phase 0 Clinical Not yet recruiting 1 12 Months 200 Chengxiang Wang, Shan Zhang 2020-10-07
Analysis on the Distribution of TCM Syndromes in convalescent novel coronavirus pneumonia (COVID-19) patients Coronavirus disease 19 infection, Viral pneumonia Beijing University of Chinese Medicine Beijing institute of Traditional Chinese Medicine China 2020-08-01 ChiCTR2000038739, ChiMCTR2000003991 Phase 0 Clinical Not yet recruiting 1 800 Chengxiang Wang, Shan Zhang 2020-10-06
Angiotensin (1-7) for the Treatment of COVID-19 in Hospitalized Patients Coronavirus disease 19 infection angiotensin (1-7) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Stanford University US 2020-11-30 2021-05-31 58189, NCT04570501 Phase 1/Phase 2 Clinical Not yet recruiting 1 6 Months 160 Kevin V Grimes, MD 2020-10-07
An observational, single-center study to determine if early treatment of patients with COVID-19 pneumonia with tocilizumab and/or steroids was associated with better outcome Coronavirus disease 19 infection, Pneumonia methylprednisolone alone, tocilizumab alone, methylprednisolone plus tocilizumab Universita Degli Studi di Genova Phase Not Applicable Status not specified 0 196 2020-10-04
An experimental study to find out the impact of post COVID physiotherapy and rehabilitation in Bangladesh Coronavirus disease 19 infection physiotherapy alone, rehabilitation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Bangladesh Physiotherapy Association Bangladesh 2020-10-07 CTRI/2020/10/028179 Phase Not Applicable Not yet recruiting 1 300 KM Amran Hossain, Mohammad Anwar Hossain 2020-10-17
A cross sectional study to identify the symptoms that are presenting by COVID-19 suffering people in Bangladesh Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bangladesh 2020-10-05 CTRI/2020/09/028165 Phase Not Applicable Not yet recruiting 1 1000 KM Amran Hossain, Mohammad Anwar Hossain 2020-10-07
Pediatric COVID-19 Antibody Study Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) Yokohama City University Japan Agency for Medical Research and Development Japan 2020-10-12 UMIN000041769 Phase Not Applicable Not yet recruiting 1 50 Kenichi Nishimura, Takeharu Yamanaka 2020-10-04
A clinical trial to know the efficacy of Homoeopathic medicine as an adjuvant therapy to Standard treatment in COVID-19 patients Coronavirus disease 19 infection homoeopathic intervention alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Homoeopathy ESI Hospital Ayanavaram India 2021-10-04 CTRI/2020/09/028164 Phase Not Applicable Not yet recruiting 1 50 Dr Nithiyaselvi, Dr Raja manoharan 2020-10-17
A prospective cohort study of the effects of COVID-19 in pregnancy and the neonatal period Coronavirus disease 19 infection Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Government Medical College, Nagpur France, Ghana, Japan, Pakistan, Russian Federation, Nigeria, Brazil, Macedonia, The Former Yugoslav Republic of, Spain, Argentina, UK, Indonesia, Mexico, Egypt, Italy, US, India 2020-10-01 CTRI/2020/09/028162 Phase Not Applicable Not yet recruiting 17 1500 Dr Manjushri Waikar 2020-10-03
CPT-R-Nepal: Clinical Protocol for Convalescent Plasma and Remdesivir Therapy in Nepal Coronavirus disease 19 infection standard of care alone, convalescent plasma plus remdesivir COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Nepal Health Research Council Ministry of Health and Population, Nepal Nepal 2020-07-30 2020-12-30 CPT-R-Nepal, NCT04570982, NHRC2020-001 Phase Not Applicable Recruiting 6 5 Months 200 Anup Bastola, MD., Dr. Pradip Gyanwali,MD, Janak Koirala, MD, MPH, Krishna Pokhrel, MD., Meghnath Dhimal, PhD, Pradip Gyanwali, MD, Rajan Pandey, MD., Santa K Das, MD., Saroj Bhattarai, MSc., Sher B Kamar, MD., Uday N Singh, MD. 2020-10-03
Oral VIRANORM (Ayurvedic Proprietary Medicine) Compared to Placebo in Subjects with Asymptomatic or Mild COVID-19 Coronavirus disease 19 infection Standard of Care (SOC) alone, VIRANORM alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) LK Wellness center India 2020-10-05 CTRI/2020/09/028158 Phase Not Applicable Not yet recruiting 3 250 Dr Padmanaban KG, Dr S Poorna Prasad, Dr Sridhar MK, Dr V Channaraya 2020-10-20
GI-COVID: GM-CSF Inhalation to Prevent ARDS in COVID-19 Pneumonia Coronavirus disease 19 infection, Hypoxia, Respiratory distress syndrome, Viral pneumonia molgramostim alone, rapid nebulizer system alone CSF-1 agonist, GM-CSF receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Giessen Germany 2020-09-24 2022-12-25 2020-001654-21, GI-COVID, KKS-279, NCT04569877 Phase 2 Clinical Recruiting 1 27 Months 238 Nelli Ens-Jäger, Susanne Herold, Prof., Susanne Herold, Prof. Dr. 2020-10-21
Perspective of MBBS Students towards Teaching through Onscreen Classes Coronavirus disease 19 infection Onscreen classes alone Adolescents (13-17 yrs), Young Adults (18-44 yrs) Punjab Institute Of Medical Sciences India 2020-10-10 CTRI/2020/09/028157 Phase Not Applicable Not yet recruiting 1 500 Dr Baljit Jassal, Dr Nipunjot Grewal, Rakesh Kumar 2020-10-01
Multicenter Study of the Integrative and Complementary Practice of the Use of Ozone Gas in Outpatients with COVID-19 Coronavirus disease 19 infection conventional treatment alone, ozone therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Philozon Group Brazil 2020-09-25 30883120.8.1001.0008, 4,100,138, RBR-97nt6j, U1111-1257-7973 Phase 1/Phase 2 Clinical Not yet recruiting 1 142 Arnoldo de Souza 2020-10-17
Comparative Study of Artificial Intelligence and Radiologists in Assessing Severity of COVID19 Patient Images Coronavirus disease 19 infection LungIQ alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Predible Health Private Limited India 2020-10-04 CTRI/2020/09/028156 Phase Not Applicable Not yet recruiting 1 500 Dr Amit Kumar Sahu 2020-10-17
A survey is to study the prophylactic effect of homoeopathic medicine namely Arsenicum album 30 against COVID 19 infection in Madurai Tamilnadu Coronavirus disease 19 infection Arsenicum Album 30C alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Homoeopathy India 2020-10-05 CTRI/2020/09/028153 Phase Not Applicable Not yet recruiting 1 10000 Dr Austin Jose, Dr karthikeyan 2020-10-03
Oral VIRAHALT (Novel Immunomodulatory Herbal combination) Compared to standard of care in Subjects with Moderate to Severe COVID-19 Coronavirus disease 19 infection Standard of Care alone, VIRAHALT (Immunomodulatory Herbal combination) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) LK Wellness center India 2020-10-05 CTRI/2020/09/028133 Phase Not Applicable Recruiting 2 60 Dr Padmanaban KG, Dr S Poorna Prasad, Dr V Channaraya 2020-10-20
Research on the maintenance and improvement of physical and mental functions of elderly people under the self-restraint caused by COVID-19 by using a remote system to connect their homes Coronavirus disease 19 infection, Muscle weakness, Psychiatric disorder information and communication technology alone, online gymnastics and exercise instructions alone, online interactive communication alone, salon-gymnastics physical therapy alone, tele-rehabilitation alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) Okayama healthcare professional university Japan 2020-07-01 UMIN000041458 Phase Not Applicable Not yet recruiting 1 40 Kazunori Kojima 2020-10-17
NHS CHECK: The psychosocial impact of the COVID-19 pandemic on NHS affiliated staff - monitoring the response to the pandemic and the evaluation of local and national staff support programs Coronavirus disease 19 infection, Psychiatric disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) King's College London Medical Research Council, NIHR Maudsley Biomedical Research Centre, Rosetrees Trust, University College London UK 2020-04-01 2022-04-23 IRAS 282686, CPMS 46176, ISRCTN18395399, NHS CHECK Phase Not Applicable Recruiting 18 24 Months 20000 Miss Rupa Bhundia, Prof Simon Wessely 2020-10-06
Auscul-X: Evaluating Auscul-X, a Touch Free Digital Stethoscope Coronavirus disease 19 infection Auscul-X System alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) AusculSciences Canada Inc Ottawa Heart Institute Research Corp Canada 2020-09-30 2021-01-31 AUSCUL-X, Auscul-X, NCT04570189 Phase Not Applicable Not yet recruiting 1 4 Months 40 Aun Yeong Chong, BSc(Med),MD, Benjamin Chow, MD, Benjamin Chow, MD,FRCPC, Farrah Ahmed, BSc., John Phillips, BSc., Melissa Spero, CRN, CCRP 2020-10-17
Intravenous L-Citrulline to Delay and Potentially Prevent the Need for Invasive Mechanical Ventilation for Acute Hypoxemic Respiratory Failure in Patients With COVID-19 (SARS-CoV-2) Illness Coronavirus disease 19 infection, Hypoxia, Respiratory failure L-citrulline alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Asklepion Pharmaceuticals LLC US 2020-09-28 2021-12-28 CIT-COVID19-002-01, NCT04570384 Phase 2 Clinical Not yet recruiting 1 15 Months 60 Gurdyal Kalsi, MD, MFPM, Michael P Wilson, MD, Nikhil K Meena, MD, Study Site Contact, Vincent Elliott 2020-10-08
Effect of Nasal Steroid in the Treatment of Anosmia Due to COVID-19 Disease Ageusia, Coronavirus disease 19 infection, Dysomia Ophtamesone alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Iraq 2020-08-01 2020-10-15 1148, NCT04569825 Phase 0 Clinical Recruiting 1 2 Months 250 Raid M Al-Ani, FIBMS (ENT) 2020-10-07
Ravulizumab and COVID-19 Coronavirus disease 19 infection, Thrombotic microangiopathy ravulizumab alone, standard care alone Complement C5 factor inhibitor, IgG receptor FcRn large subunit p51 modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Brigham & Women's Hospital US 2020-11-30 2021-11-30 092420, NCT04570397 Phase 3 Clinical Not yet recruiting 1 12 Months 32 Aliza Anwar Memon, M.B.B.S, Andrew M Siedlecki, M.D 2020-10-05
A cross sectional study to assess the impact of COVID-19 on patints with non communicable disease at AYUSH LSD clinics Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Council for Research in Homoeopathy India 2020-10-05 CTRI/2020/09/028132 Phase Not Applicable Not yet recruiting 2 450 Dr Debadatta Nayak, Dr Praveen Oberai, Dr Varanasi Roja 2020-10-01
BigCoviData: Clinical Characteristics and Prognostic Factors of Patients With COVID-19 (Coronavirus Disease 2019) Coronavirus disease 19 infection, Viral pneumonia Big Data system alone Medsavana Castilla-La Mancha Health Service Spain 2020-01-01 2021-10-30 BIGCOVIDATA, BigCoviData, NCT04569851 Phase Not Applicable Recruiting 2 21 Months 100000 Joan B Soriano, MD, PhD, José Luis Izquierdo, MD, PhD, Julio Ancochea, MD, PhD 2020-10-17
A study of Cordyceps Capsules as an Add-On Therapy in patients with moderate COVID 19 Infection Coronavirus disease 19 infection Cordyceps Capsules alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) India 2020-10-02 CTRI/2020/09/028131, Cordyceps-2001 Phase Not Applicable Not yet recruiting 1 60 Dr Sagar Sinha, Prof Dr Siddharth P Dubhashi 2020-10-05
Homoeopathy in the prevention of COVID-19 Coronavirus disease 19 infection Arsenicum album 30 alone, Influenzinum 30 alone, Oscillococcinum alone Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Mahesh Bhattacharyya Homoeopathic Medical College, Ministry of Ayush India 2020-10-06 CTRI/2020/09/028122 Phase 3 Clinical Not yet recruiting 1 15992 Malay Mundle, Shubhamoy Ghosh 2020-10-05
ANTIOX-COVID: Antioxidants as Adjuvant Therapy to Standard Therapy in Patients With COVID-19 Coronavirus disease 19 infection, Septic shock, Viral pneumonia Variable regimens including N-acetyl cysteine , melatonin , pentoxifylline , vitamin C , vitamin E Phosphoric diester hydrolase inhibitor Instituto Nacional de Cardiologia Ignacio Chavez, Instituto Nacional de Ciencias Medicas y Nutricion Mexico 2020-08-19 2020-11-15 09-CEI-011-20160627, ANTIOX-COVID, NCT04570254 Phase 2 Clinical No longer recruiting 1 2 Months 11 Adrián Palacios Chavarria, MD, José Guillermo Domínguez Cherit, MD, Maria Elena Soto Lopez, PhD 2020-10-07
A study to evaluate the response to and recovery from total knee arthroplasty (TKA) in patients with antibodies to COVID-19 Coronavirus disease 19 infection, Knee injury total knee arthroplasty (TKA) alone Hospital for Special Surgery NY US Phase Not Applicable Status not specified 1 Meghan A. Kirksey, Miguel Otero, Peter K. Sculco 2020-10-01
A clinical study to evaluate the mechanisms of cytokine storm in patients with COVID-19 Coronavirus disease 19 infection anakinra alone Type I IL-1 receptor antagonist Hospital for Special Surgery NY US Phase Not Applicable Status not specified 1 Lionel B. Ivashkiv, Mary K. Crow, Mikhail Olferiev 2020-10-01
STORM-HCW: Screening of Health-care Workers in an University Hospital for SARS-CoV-2 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Milano-Bicocca Italy 2020-06-01 2020-12-01 NCT04567836, STORM-HCW, STORM-HCW Phase Not Applicable Recruiting 1 6 Months 3000 Paolo Bonfanti 2020-10-08
HOW-R-U? CTP: Feasibility and acceptability of a volunteer-peer telephone support programme - A COVID-19 response Coronavirus disease 19 infection, Depression supportive telephone calls alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bolton Clarke, Northern Hospital, Australia Australia 2020-10-05 ACTRN12620000975998, HOW-R-U? CTP Phase Not Applicable Not yet recruiting 2 100 Dr Marissa Dickins, Prof Judy Lowthian 2020-10-16
National Asthma Treatment Survey in Australian adults Coronavirus disease 19 infection web-based survey alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Oceanic Ancestry National Health and Medical Research Council, Woolcock Institute of Medical Research Australia, New Zealand 2020-11-01 2020-11-15 ACTRN12620000977976p, U1111-1257-3764 Phase Not Applicable Not yet recruiting 2 8000 Dr Sharon Davis, Prof Helen Reddel 2020-10-13
TPEP-Corona-1: A randomized, double-blind, placebo-controlled trial of oral ivermectin for outpatient treatment of those at high risk for hospitalization due to COVID-19 Coronavirus disease 19 infection, Viral pneumonia ivermectin alone Chloride channel modulator Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Neuroscience Trials Australia Leona M and Harry B Helmsley Charitable Trust Australia 2020-10-05 ACTRN12620000982910p, TPEP-Corona-1 Phase 3 Clinical Not yet recruiting 1 400 Dr Mark Stein, Ms Michele Sallaberger 2020-10-13
Micronized and Ultramicronized Palmitoylethanolamide in COVID-19 Patients Coronavirus disease 19 infection, Inflammatory disease, Neuritis, Viral pneumonia Normast MPS (Epitech Group Srl) alone, standard therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Epitech Group Srl Azienda Ospedaliera Sant' Andrea Italy 2020-10-31 2021-11-30 NCT04568876, NORM_MPS-COVID, NORM_MPS_11 Phase 4 Clinical Not yet recruiting 1 13 Months 40 Epitech Group SpA Clinical Research, Prof.ssa Flaminia Coluzzi, MD 2020-10-03
The Phase I Clinical Trial of Booster Vaccination of Adenovirus Type-5 Vectored COVID-19 Vaccine Coronavirus disease 19 infection Ad5-nCoV alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Jiangsu Province Centers for Disease Control and Prevention China 2020-09-26 2021-09-27 JSVCT100, NCT04568811 Phase 1 Clinical No longer recruiting 1 12 Months 89 2020-10-05
Study of AZD-1222 for the Prevention of COVID-19 in Japan Coronavirus disease 19 infection AZD-1222 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) AstraZeneca plc IQVIA RDS Pty Ltd Japan 2020-08-23 2021-09-06 D8111C00002, NCT04568031 Phase 1/Phase 2 Clinical Recruiting 5 12 Months 256 AstraZeneca Clinical Study Information Center 2020-10-20
SAR-COVID: Argentinian Registry of Patients With Rheumatic Diseases and COVID-19 Infection Coronavirus disease 19 infection, Joint disease Immunosuppressive drug treatment alone, immunomodulatory drug treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Argentina 2020-08-18 2021-12-31 01, NCT04568421, SAR-COVID Phase Not Applicable Recruiting 1 16 Months 3000 Carolina Isnardi, MD, Guillermo Pons-Estel, Guillermo Pons-Estel, PhD, Guillermo Posn-Estel, PhD 2020-10-06
Prevention of COVID-19 Infection to Severe Pneumonia or ARDS Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia mosedipimod alone CCL26 gene inhibitor, TLR modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Enzychem Lifesciences Corp US 2020-10-06 2021-11-30 EC-18-204, NCT04569227 Phase 2 Clinical Not yet recruiting 1 13 Months 60 Dr. Cameron Robert Wolfe, Ji Sun Park, Ph.D., John Choi, M.S. 2020-10-01
Minnesota COVID-19 Testing Project Coronavirus disease 19 infection emphasis of government involvement alone, messaging alone, survey incentive alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Harvard University Abdul Latif Jameel Poverty Action Lab, Government of Minnesota US 2020-09-28 2021-06-30 IRB20-1444, NCT04568889 Phase Not Applicable Not yet recruiting 1 9 Months 1000 Marcella Alsan, MD, MPH, PhD, Min Jeong (Joyce) Kim, BS 2020-10-16
A clinical trial of COVID-19 inactivated vaccine (Vero cell) for the potential prevention of COVID-19 Coronavirus disease 19 infection COVID-19 vaccine (inactivated/Vero cells/intramuscular, SARS-CoV-2 infection), Shenzhen Kangtai Biological Products alone Shenzhen Kangtai Biological Products Co Ltd China Phase Not Applicable Not yet recruiting 1 2020-10-15
RECOVER: Effectiveness of an Exercise Re-training Program on Dyspnea in Patients After Acute Respiratory Distress Syndrome Secondary to Severe COVID-19 Pneumonia in Post-ICU Coronavirus disease 19 infection, Dyspnea, Respiratory distress syndrome, Viral pneumonia specific exercise rehabilitation treatment alone, strengthening exercise alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Groupe Hospitalier Paris Saint-Joseph Assistance Publique Hopitaux de Paris, Central Hospital, Versailles, Centre Hospitalier Victor Dupouy, Saint Anne's Hospital France 2020-08-07 2022-05-07 NCT04569266, RECOVER, RECOVER Phase Not Applicable Recruiting 1 21 Months 200 PHILIPPART François, MD, ROMANET Christophe 2020-10-13
BIO-COCO-NEUROSCIENCES: Evaluation of Biological Response to SARS-COV2 (COVID-19) in Patients With Pre-existing Neurological Disease or Newly Neurological Symptoms Coronavirus disease 19 infection, Neurological disease, Psychiatric disorder PCR alone, chest scanner alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris Institut du Cerveau et de la Moelle epiniere France 2020-10-15 2022-10-15 APHP200845, BIO-COCO-NEUROSCIENCES, NCT04568707 Phase Not Applicable Not yet recruiting 1 24 Months 200 Céline LOUAPRE, MD 2020-10-13
A Clinical Evaluation of COVID-19 Rapid Point of Care Antigen Tests Coronavirus disease 19 infection, Respiratory tract infection SARS-CoV-2 direct antigen rapid test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) E25Bio Inc Sarah Cannon Research Institute US 2020-04-24 2020-09-24 E25001_NEU2012, NCT04568356 Phase Not Applicable Completed 3 5 Months 200 Gina Remington, RN MSN, Klepler N De Almeida, MD, Patrice Feaster, RN 2020-10-20
COICA: COVID-19 Infection in Cancer Pantients Coronavirus disease 19 infection, Urinary tract tumor Andrea Tortora di Pagani Hospital Italy 2020-01-01 2021-08-31 COICA, COICA_PAG_01, NCT04569292 Phase Not Applicable Recruiting 1 20 Months 150 Data Manager Oncology Unit, Giuseppe Di Lorenzo 2020-10-16
Telerehabilitation in Lung Surgery Patients Coronavirus disease 19 infection, Lung tumor Telerehabilitation alone, exercise program alone, progressive mobilization program alone, teleconference exercise alone, thoracotomy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Istanbul Medipol University Hospital Turkey 2020-10-01 2021-05-01 NCT04568564, PostopTele Phase Not Applicable Recruiting 1 7 Months 40 Akif Turna, Prof.Dr., Esra Pehlivan, Assoc.Prof., esra pehlivan, Principal investigator 2020-10-14
COVID-19 Tests With Saliva Specimens Coronavirus disease 19 infection Orasure collection kit alone, SDNA1000 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Paradigm US 2020-07-28 2021-06-27 NCT04567953, PLRD202001 Phase Not Applicable No longer recruiting 1 11 Months 2000 Wenli Zhou, PhD 2020-10-16
Combination of Chemopreventive Agents (All- Trans Retinoic Acid and Tamoxifen) as Potential Treatment for the Lung Complication of COVID-19 Coronavirus disease 19 infection, Lung disease, Respiratory failure, Respiratory tract infection standard treatment alone, all trans retinoic acid plus tamoxifen Estrogen receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kafrelsheikh University Egypt 2020-09-30 2020-11-30 COVID-2019, NCT04568096 Phase 2 Clinical Not yet recruiting 2 2 Months 160 Mahmoud Elkazzaz, B.Sc,M.Sc in Biochemistry 2020-10-05
A retrospective study to evaluate the efficacy and safety of anakinra in patients with COVID-19 associated pneumonia and acute severe respiratory failure Coronavirus disease 19 infection, Inflammatory disease, Respiratory distress syndrome, Viral pneumonia anakinra alone, standard-of-care treatment alone Type I IL-1 receptor antagonist Aix-Marseille Université France Phase Not Applicable Status not specified 1 22 2020-09-30
RESCUE: Convalescent Plasma in COVID-19 Elderly Patients Coronavirus disease 19 infection, Respiratory failure convalescent plasma alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) Azienda Socio Sanitaria Territoriale di Mantova Italy 2020-05-15 2020-09-03 ASSTMANTOVA, NCT04569188, RESCUE Phase 2 Clinical Completed 1 3 Months 21 Massimo Franchini 2020-10-05
ImmunoCOVID: Evaluation of Humoral Immunity Following COVID-19 in Pregnancy Coronavirus disease 19 infection, Influenza virus infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Imperial College London UK 2020-09-16 2023-07-03 20SM6089, ImmunoCOVID, NCT04568044 Phase Not Applicable Recruiting 2 33 Months 96 Charlotte-Eve Short, PhD, Head of Research Governance and Integrity, Nishel M Shah, PhD, Research Delivery Operations Manager, Senior Research Facilitator 2020-10-01
A case-control study to compare RLF-100 with standard of care in the treatment of patients with critical COVID-19 and respiratory failure Coronavirus disease 19 infection, Respiratory failure aviptadil (inhaled, sarcoidosis/acute lung injury/acute respiratory distress syndrome associated COVID-19), Relief Therapeutics Holding alone Adrenergic receptor antagonist, VIP receptor agonist NeuroRx Inc Phase Not Applicable Status not specified 0 51 2020-10-05
Safety, Tolerability, and Pharmacokinetics of Anti-Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Chicken Egg Antibody (IgY) (COVID-19) Coronavirus disease 19 infection anti-SARS-CoV-2 IgY (intranasal, COVID-19), Stanford University alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Stanford University Australia 2020-09-18 2020-12-31 CVR001, NCT04567810 Phase 1 Clinical Recruiting 1 3 Months 48 Daria Mochly-Rosen, PhD, Michaela Lucas, MD, Study Team 2020-10-19
Passive Microwave Radiometry (MWR) and AI for COVID-19 Complications Early Diagnostics of Lungs Coronavirus disease 19 infection, Viral pneumonia MWR2020 alone, passive microwave radiometry alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Kyrgyz State Medical Academy International Medical University, University of Edinburgh Kyrgyzstan 2020-07-01 2020-08-01 01-2/141 27, NCT04568525 Phase Not Applicable Completed 1 1 Month 195 Batyr Osmonov 2020-10-16
The Noninvasive Ventilation to COVID-19 Patients Coronavirus disease 19 infection, Respiratory failure noninvasive ventilation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The First Affiliated Hospital of Guangzhou Medical College China 2020-02-01 2020-07-01 FAHGUANGZHOUYLS03, NCT04568655 Phase Not Applicable Completed 1 5 Months 23 Zhang Jianheng 2020-10-02
Waxing and Waning of Serum SARS CoV-2-IgG Level in COVID-19 Exposed Population Coronavirus disease 19 infection Services Hospital Pakistan 2020-07-01 2020-11-30 LGH007, NCT04568850 Phase Not Applicable No longer recruiting 1 5 Months 50 Amina Asif, MPhilMicro 2020-10-16
Prevalence and Risk Factors for Venous Thromboembolic Events in Critically Ill Patients With COVID-19 Coronavirus disease 19 infection, Deep vein thrombosis, Respiratory failure color doppler alone, ultrasonography alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Switzerland 2020-03-03 2020-05-28 2020-01266, NCT04567927 Phase Not Applicable Completed 1 2 Months 80 Chiesa Alessandro Felice 2020-10-01
A Survey Study to Assess the Impact of the COVID-19 Pandemic on Participants With Pre-Existing Mental Health Diagnosis Coronavirus disease 19 infection, Psychiatric disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Siyan Clinical Corp US 2020-10-31 2021-12-31 NCT04568135, SCR-SUR-001 Phase Not Applicable Not yet recruiting 2 14 Months 1000 Tiffany Morgan 2020-10-14
Effect of Inhaled Nitric Oxide for the treatment of COVID-19 Coronavirus disease 19 infection nitric oxide alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Council for Scientific and Technological Development Brazil 2020-10-10 34578820.6.1001.5336, 4,282,107, RBR-8nfx26, U1111-1254-0466 Phase 2 Clinical Not yet recruiting 1 110 Marcus Herbert Jones, Marcus Jones 2020-10-05
Presenting Nutrition Characteristics, Comorbidities and Outcomes of COVID-19 in African Humanitarian Settings Coronavirus disease 19 infection Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Johns Hopkins Bloomberg School of Public Health Centers for Disease Control and Prevention Sudan, Congo, The Democratic Republic of the 2020-10-31 2021-03-31 13736, NCT04568499 Phase Not Applicable Not yet recruiting 2 5 Months 1000 Shannon Doocy, PhD 2020-10-01
Prospective Determination of COVID-19 Infection Rate in a Chemotherapy Unit in Mexico Coronavirus disease 19 infection polymerase chain reaction alone Instituto Nacional de Ciencias Medicas y Nutricion National Institute Of Genomic Medicine Mexico Mexico 2020-06-11 2020-10-30 HEM-3412-20-20-1, NCT04567979 Phase Not Applicable No longer recruiting 1 4 Months 149 David Huitzil m, Fidel D Huitzil Meléndez, MD 2020-10-01
COVID-19 Biorepository Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Kansas Medical Center US 2020-04-15 2021-12-31 NCT04568148, STUDY#00145602 Phase Not Applicable Recruiting 1 20 Months 50 Christine M Cook, MD, Leslie A Spikes, MD, Luigi R Boccardi, BS 2020-10-02
Surfactant-BL in Adult Acute Respiratory Distress Syndrome Due to COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure High-flow oxygen therapy alone, Standard treatment alone, non-invasive ventilation alone, surfactant-BL, Biosurf LLC alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Russian Federation 2020-07-03 2021-12-31 NCT04568018, SUR/ARDS-2020 Phase Not Applicable Recruiting 1 17 Months 120 Anastasia Evdokimova, Sergey Avdeev, D.M.S. 2020-10-06
Safety, Tolerability and Immunogenicity of the Candidate Vaccine MVA-SARS-2-S Against COVID-19 Coronavirus disease 19 infection MVA-SARS-2-S alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Universitätsklinikum Hamburg-Eppendorf Deutsches Zentrum für Infektionsforschung, Ludwig-Maximilians University of Munich, Philipps University Marburg Medical Center Germany 2020-10-31 2021-05-31 NCT04569383, UKE-DZIF-SARS-COV-2 Phase 1 Clinical Not yet recruiting 1 7 Months 30 Marylyn M Addo, MD 2020-10-13
Evaluation of Lymphedema Patients Status During COVID-19 Pandemic Anxiety disorder, Coronavirus disease 19 infection, Depression, Lymphedema, Phobia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fatih Sultan Mehmet Training and Research Hospital Turkey 2020-06-01 2020-08-01 FEYZAAKANBEGOGLU, NCT04568005 Phase Not Applicable Completed 1 2 Months 60 Feyza Akan Begoğlu, MD 2020-10-08
CAASP: COVID-19-associated Anxiety of Pregnant Women for Anomalies, Stillbirth and Preterm Labor Anxiety disorder, Coronavirus disease 19 infection Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Martin-Luther-Universitaet Germany 2020-10-01 2021-07-31 CAASP, NCT04568551, UKGEB001 Phase Not Applicable Recruiting 1 10 Months 300 Marcus Riemer, Marcus Riemer, MD 2020-10-05
Rapid Turnaround, Home-based Saliva Testing for COVID-19 Coronavirus disease 19 infection HandyFuge-LAMP alone, Saliva test alone, loop-mediated isothermal amplification (LAMP) assay alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Stanford University US 2020-10-31 2021-04-30 58629, NCT04568122 Phase Not Applicable Not yet recruiting 1 6 Months 3015 Euan A Ashley, MRCP, DPhil, Manisha Desai, PhD, Manu Prakash, PhD 2020-10-13
COVID-19 and Venous Thromboembolism Risk Coronavirus disease 19 infection, Thromboembolism Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of California San Francisco Kaiser Permanente, Patient Centered Outcome Research Institute US 2020-01-01 2022-06-21 NCT04569344, NOACS-1510-32651_ENHANCEMENT Phase Not Applicable Recruiting 3 29 Months 40000 Margaret C Fang, MD 2020-10-21
A phase II clinical trial of tolimidone in the treatment of patients who were recently diagnosed with COVID-19, have early symptoms, but were not hospitalized Coronavirus disease 19 infection tolimidone alone Insulin sensitizer, Lyn tyrosine kinase stimulator Melior Pharmaceuticals Inc University of Pittsburgh Medical Center Phase 2 Clinical Planned 0 428 2020-09-30
Effect of poor sleep hygiene and screen time usage on sleep Acute stress disorder, Coronavirus disease 19 infection Young Adults (18-44 yrs) Sri Ramachandra Institute of Higher Education and Research India 2020-10-01 CTRI/2020/09/028083 Phase Not Applicable Not yet recruiting 1 330 Dr Priscilla Johnson, V Sudha Kumari 2020-10-01
ARIAA-2: Adaptability and Resilience in Aging Adults-2 Coronavirus disease 19 infection, Lower back pain Resilience Intervention alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Florida National Institute on Aging US 2020-01-21 2021-05-01 4R00AG052642-03, 5K99AG052642-02, ARIAA-2, IRB201802729, NCT04068922 Phase Not Applicable Recruiting 1 15 Months 60 Emily Bartley, PhD, Emily J Bartley, Ph.D 2020-10-06
REPERCOV: Identifying Functional and Psycho-social Complaints After Hospitalization for SARS-CoV-2 Infection (COVID 19) Coronavirus disease 19 infection, Psychiatric disorder questionnaire alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier le Mans France 2020-06-11 2022-06-11 CHM-2020/S10/04, NCT04561154, REPERCOV Phase Not Applicable Recruiting 1 24 Months 134 Christelle JADEAU, Hikombo HITOTO 2020-10-06
A phase I, multicenter, randomized, controlled trial to evaluate the safety and efficacy of inhaled Ampion in combination with standard of care for the treatment of COVID-19 infected patients hospitalized for respiratory distress Coronavirus disease 19 infection, Respiratory distress syndrome Ampion (intranasal, inflammation), Ampio/DMI Biosciences alone, standard of care alone Stem cell antigen-1 inhibitor Ampio Pharmaceuticals Inc Phase 1 Clinical Not yet recruiting 0 40 2020-09-30
Variation in biochemical parameters in COVID-19 infection Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Sri Ramachandra Institute of Higher Education and Research India 2020-10-01 CTRI/2020/09/028069 Phase Not Applicable Not yet recruiting 1 150 Dr K Sowmya 2020-10-01
The Causal Effects of Old Age Pensions Coronavirus disease 19 infection Assistance with old age pension application alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Bureau of Economic Research Inc India 2019-02-04 2027-12-31 223749, NCT04029194 Phase Not Applicable No longer recruiting 1 106 Months 1459 Esther Duflo 2020-09-30
Self-help Guided by Lay Providers for Anxiety in Older Adults Coronavirus disease 19 infection, Generalized anxiety disorder Self-help guided by a lay provider alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universite Laval Canadian Institutes of Health Research, Convenance institutionnelle CIUSSS de la Capitale-Nationale, Universite de Sherbrooke Canada 2019-03-11 2023-03-31 NCT03768544, SIRUL 118715 Phase Not Applicable Recruiting 3 48 Months 130 Catherine Filion, M.A., Félix-Antoine Desruisseaux, B.A., Patrick Gosselin, Ph.D., Philippe Landreville, Ph.D., René-Marc Lavigne, Ph.D., Sébastien Grenier, Ph.D. 2020-10-05
Vaginal Cleansing Before Cesarean Delivery to Reduce Infection Coronavirus disease 19 infection, Vaginal infection Abdominal Cleansing alone, Vaginal Cleansing alone, betadine alone, chlorhexidine alone, povidone-iodine alone Healthy volunteers accepted, Female Washington University in St Louis US 2015-08-31 2021-03-31 201505127, NCT02495753 Phase 2 Clinical Recruiting 1 67 Months 608 Alison G Cahill, MD, Antonina I Frolova, MD, Lorene A Temming, MD 2020-10-01
An observational, retrospective study to evaluate the outcomes of tocilizumab in patients with severe coronavirus disease 2019 Coronavirus disease 19 infection antiviral agents alone, tocilizumab alone Hamad Medical Corp Phase Not Applicable Status not specified 0 25 2020-10-08
Effectiveness of an equipment to reduce the dispersion of particles in emergency dental care during the Covid-19 pandemic Coronavirus disease 19 infection, Tooth disease protective equipment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Pontifícia Universidade Católica - PUCPR Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul Brazil 2020-09-01 30717820.1.0000.5336, 4.021.042, RBR-9rnkbs, U1111-1258-5375 Phase Not Applicable Recruiting 1 Maximiliano Schunke Gomes 2020-09-30
Supporting the Health and Well-being of Children With Intellectual and Developmental Disability During COVID-19 Pandemic Coronavirus disease 19 infection, Intellectual impairment Best Message + Augmented Message or Implementation Strategy alone, Best Message Alone alone, Focused/Targeted Message alone, General Communication Message alone Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Washington University School of Medicine, US Hugo W. Moser Research Institute at Kennedy Krieger, Inc, National Institutes of Health, University of Missouri US 2020-11-01 2022-09-21 202009060, NCT04565509 Phase Not Applicable Not yet recruiting 2 22 Months 2500 Bradley Schlaggar, MD, PhD, George S Grotto, PhD, Jason G. Newland, MD 2020-10-01
Testing Multiple Behavioral Science Strategies to Increase Flu-Shot Rates Coronavirus disease 19 infection, Influenza virus infection Flu shot text messages alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Pennsylvania State University Geisinger Clinic US 2020-09-20 2021-03-31 843523, NCT04565353 Phase Not Applicable Recruiting 2 6 Months 125600 Dena Gromet, PhD, Joseph Kay, PhD, Joseph S Kay 2020-10-14
DPPFit: Developing and Testing a Technology-Based Translation of the DPP to Address Prediabetes in a Primary Care Setting Coronavirus disease 19 infection, Non-insulin dependent diabetes Diabetes Prevention Program alone, Fitbit alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Augusta University US 2020-01-01 2021-02-15 DPPFit, IRB#1193356, NCT04564586 Phase Not Applicable No longer recruiting 1 13 Months 32 Jessica L Stewart, MPH 2020-10-01
Pilot Study to Evaluate Effect of CHX0.12/CPC 0.05 of SARS-CoV-2 Viral Load in COVID-19 Patients Coronavirus disease 19 infection CHX0.12+CPC0.05 oral rinsing alone, Chlorhexidine + Cetyl Pyridinium Chloride alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dentaid, S.L. Colombia 2020-06-18 2020-12-31 COVID-POC1, NCT04563689 Phase Not Applicable Recruiting 1 6 Months 24 Adolfo Contreras, prof, Beatriz Parra, PhD, Juan Gispert, MD, Ruben Leon, PhD, Vanessa Blanc, PhD 2020-10-05
ACPREGCOV: Active Pregnancy Against COVID-19 Coronavirus disease 19 infection, Pregnancy disorder Exercise program alone Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Universidad Politecnica de Madrid Hospital Puerta de Hierro Majadahonda, Hospital Universitario Severo Ochoa, Hospital Vall D'Hebron, University Hospital of Torrejon Spain 2020-08-01 2023-12-31 ACPREGCOV, NCT04563065, UPM-2020-32/33 Phase Not Applicable Recruiting 2 41 Months 280 Aranzazu Martin, Dr, Cristina Silva-Jose, Msc, Cristina Silva-José, MsC, Ignacio Refoyo, Dr, Irene Buhigas, Dr, Irune Alzola, Dr, Javier Coterón, Dr, Javier Gil, Dr, Maia Brik, Dr, Mar Gil, Dr, Miguel Sanchez-Polan, Msc, Rubén Barakat, Rubén Barakat Carballo, Rubén Barakat, Dr, Tirso Perez, Dr, Vanessa Carrero, Dr, Ángeles Blanco, Dr 2020-10-01
XatJove Anoia, as a Tool to Bring Health Services Closer to Teenagers Coronavirus disease 19 infection XatJove Anoia Aplication alone Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs) Jordi Gol i Gurina Foundation Catalan Health Service Spain 2020-10-01 2021-10-11 20/137-P, NCT04562350 Phase Not Applicable Recruiting 1 12 Months 500 Glòria Saüch Valmaña, Josep Vidal-Alaball, PhD, Nuria Carré Llopis, RN, Núria Carré Llopis, RN 2020-10-01
Evaluation of the effect of education in the prevention of covid-19 Coronavirus disease 19 infection protection motivation theory-based educational program alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hamadan University of Medical Sciences Iran 2020-09-22 IR.UMSHA.REC.1399.476, IRCT20200902048598N1 Phase Not Applicable Recruiting 1 200 Dr. Saeed Bashirian, Majid Barati, Roholah Afshar 2020-10-01
Social factors related to COVID 19 Coronavirus disease 19 infection interview alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Tata Memorial Hospital India 2020-10-07 CTRI/2020/09/028090 Phase Not Applicable Not yet recruiting 1 800 Sandeep Tandon 2020-10-01
Role of self sampling in COVID 19 patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute Of Medical Sciences, Rishikesh India 2020-10-05 CTRI/2020/09/028089 Phase Not Applicable Not yet recruiting 1 1350 Dr Amit Kumar 2020-10-01
Effects of Traditional Nasal Saline (Simply Saline) and a Novel Nasal Salt on Aerosol Cleansing Coronavirus disease 19 infection nasal mist calcium salts alone Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Bangalore Baptist Hospital Azim Premji Foundation India 2020-10-05 CTRI/2020/09/028084 Phase Not Applicable Not yet recruiting 1 80 Dr Carolin Elizabeth George 2020-10-16
Intubation and ventilatory support in COVID patients: observational study from a tertiary care ICU Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences Jai Prakash Narayan Apex Trauma Centre India 2020-10-02 CTRI/2020/09/028050 Phase Not Applicable Not yet recruiting 1 40 Dr Nishant Patel 2020-09-30
COVID-19: Telemedicine Readiness Coronavirus disease 19 infection telemedicine readiness alone Malaysia 2020-10-15 2021-10-15 56434, NMRR-20-2029-56434 Phase Not Applicable Status not specified 1 12 Months NURIZATI BINTI MAT GHANI 2020-09-30
COVID-19 Spatio-Temporal Modeling Coronavirus disease 19 infection Spatio-Temporal Modeling alone Universiti Putra Malaysia Malaysia 2020-12-01 2022-06-01 56256, NMRR-20-2031-56256 Phase Not Applicable Status not specified 1 18 Months Dr Nur Haizum binti Abd Rahman 2020-09-30
A study to assess aviptadil (inhaled, sarcoidosis/acute lung injury/acute respiratory distress syndrome associated COVID-19), Relief Therapeutics Holding for the treatment of covid-19 and respiratory failure Coronavirus disease 19 infection, Respiratory failure aviptadil (inhaled, sarcoidosis/acute lung injury/acute respiratory distress syndrome associated COVID-19), Relief Therapeutics Holding alone Adrenergic receptor antagonist, VIP receptor agonist NeuroRx Inc, Relief Therapeutics Holding AG Phase Not Applicable Status not specified 0 51 2020-10-16
CAM-Covid-19: Open-Label, Randomized trial of Colchicine, Aspirin and Montelukast in Covid-19 Coronavirus disease 19 infection, Inflammatory disease Standard of Care alone, Variable regimens including Aspirin , colchicine , montelukast sodium Leukotriene D4 antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Indira Gandhi Medical College India 2020-10-31 CAM-Covid-19, CTRI/2020/09/028088 Phase 2 Clinical Not yet recruiting 1 34 Vivek Chauhan 2020-10-05
Phase IIb Clinical Trial of A COVID-19 Vaccine Named Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector) Coronavirus disease 19 infection Ad5-nCoV alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) CanSino Biologics Inc Beijing Institute of Biotechnology, China, Jiangsu Province Centers for Disease Control and Prevention China 2020-09-24 2022-10-20 JSVCT093, NCT04566770 Phase 2b Clinical Recruiting 1 24 Months 481 Fengcai Zhu, MSD, Wenjuan Wang, MSD 2020-10-01
SCREEN: Serology to Covid for Recording Exposures and Evaluating Needs Coronavirus disease 19 infection ELISA alone, biological sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cincinnati Children's Hospital Medical Center US 2020-08-18 2023-12-31 NCT04566965, SCREEN, SCREEN Phase Not Applicable Recruiting 1 40 Months 230 Mary Allen Staat, MD, MPH, Maureen Carolin, Russell Ware, MD, PhD, Sue Poynter Wong, MD, MEd, Teresa Latham 2020-09-30
Co-CLARITY: Convalescent Plasma as Adjunctive Therapy for Hospitalized Patients With COVID-19 Coronavirus disease 19 infection anti-SARS-CoV-2 convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of the Philippines Philippine Council for Health Research and Development Philippines 2020-09-21 2021-06-30 2020-CT0554, Co-CLARITY, NCT04567173, PHRR200824-002868, UPMREB 2020-300-01 Phase 3 Clinical Recruiting 2 9 Months 136 Agnes Evasan, MD, Alric V Mondragon, MD, Anna Flor Malundo, MD, Anne Kristine H Quero, MD, Carlo Francisco N Cortez, MD, Cecile D Dungog, MD, Deonne Thaddeus Gauiran, Deonne Thaddeus Gauiran, Principal Investigator, Deonne Thaddeus V Gauiran, MD, Francisco M Heralde III, PhD, Fresthel Monica M Climacosa, MD PhD, German J Castillo Jr, MD, Ivy Mae S Escasa, MD, Januario Veloso, MD, Jodor Lim, MD, Jose M Carnate Jr, MD, Josephine Anne Lucero, MD, Lynn B Bonifacio, MD, Ma Angelina L Mirasol, MD, Maria Clariza M Santos, MD, Marissa Alejandria, MD MSc, Mark Angelo Ang, MD, Pedrito Y Tagayuna, MD, Rachelle Alfonso, MD, Ruby Anne N King, MD PhD, Sandy Chiong Maganito, MD, Teresita E Dumagay, MD 2020-09-30
ChulaCov19 mRNA Vaccine in Healthy Adults Coronavirus disease 19 infection ChulaCov19 messenger ribonucleic acid alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Chulalongkorn University Faculty of Tropical Medicine, Mahidol University, National Vaccine Institute, Thailand, The National Research Council Of Thailand Thailand 2021-01-31 2021-06-30 CHULAVAC 001, NCT04566276 Phase 1/Phase 2 Clinical Not yet recruiting 2 5 Months 96 Kiat Ruxrungtham, MD, Nitiya Chomchey, PhD, Sivaporn Gatechompol, MD 2020-10-07
Predictive Factors for COVID-19 in Rheumatology Autoimmune disease, Coronavirus disease 19 infection, Musculoskeletal disease disease modifying antirheumatic drug therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundacion Santa Fe De Bogota Colombia 2020-10-31 2021-10-31 FPCOLCOVIDREUMA2020, NCT04567576 Phase Not Applicable Not yet recruiting 1 12 Months 150 Kevin Maldonado Canonn 2020-09-30
PREVAILctDNA: Preventing Viral Pandemic Associated Risk of Cancer Death Using Less Invasive Diagnostic Tests- Liquid Biopsies Biliary cancer, Colorectal tumor, Coronavirus disease 19 infection, Gastrointestinal stromal tumor, Lung tumor, Metastasis, Metastatic bladder cancer, Metastatic pancreas cancer Blood sampling alone, Liquid biopsy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The Royal Marsden NHS Trust UK 2020-06-18 2022-12-31 CCR 5292, NCT04566614, PREVAILctDNA Phase Not Applicable Recruiting 2 30 Months 112 Justin Mencel, MBBS, Naureen Starling, Naureen Starling, MBBS MRCP MD, Scot Davies, CIBiol 2020-09-30
A study to evaluate lipemic serum in patients with CoVID‐19 undergoing lopinavir/ritonavir treatment Coronavirus disease 19 infection, Hypertriglyceridemia lopinavir + ritonavir alone HIV protease inhibitor Male Ministry of Health, Brunei Darussalam Phase Not Applicable Status not specified 0 2 2020-09-29
A trial to evaluate IVIEW-1503 for the treatment of patients with COVID-19 Coronavirus disease 19 infection IVIEW-1503 alone iVIEW Therapeutics Inc University of British Columbia Canada Phase Not Applicable Not yet recruiting 1 2020-09-29
Phase IV study to evaluate the safety and efficacy of Artemisinin- a herbal supplement on COVID-19 subjects Coronavirus disease 19 infection Artemisinin alone, Standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Windlas Biotech Pvt Ltd India 2020-09-30 ARTI/WBPL/P4/2020/01, CTRI/2020/09/028044 Phase 4 Clinical Not yet recruiting 3 120 Dr Antaryami Maharana, Mukesh Kumar 2020-09-30
Clinical study to assess role of Vasa Ghana, Guduchi Ghana and Vasa-Guduchi Ghana in therapeutic management of symptoms in Covid19 Coronavirus disease 19 infection Adhatoda vasica alone,  Tinospora cordifolia alone, Adhatoda vasica plus  Tinospora cordifolia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ministry of Ayush India CTRI/2020/09/028043 Phase 4 Clinical Not yet recruiting 1 50 DR BHAVANA PRASHER, Dr Meera K Bhojani, Prof Tanuja Manoj Nesari 2020-10-01
Seroprevalence of COVID 19 in children Coronavirus disease 19 infection Healthy volunteers accepted, Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Kanchi Kamakoti CHILDS Trust Hospital India 2020-10-05 CTRI/2020/09/028040 Phase Not Applicable Not yet recruiting 1 400 Dr Aishwarya Venkataraman 2020-09-30
Evaluation of severity of chest CT findings in covid 19 patients with pre-existing illness Coronavirus disease 19 infection chest CT findings alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) KIMS Hospital India 2020-10-20 CTRI/2020/09/028087 Phase Not Applicable Not yet recruiting 1 500 Swati Das 2020-09-30
Effect of 12-weeks of Online Sudarshan Kriya Yoga practice on Burnout and Health Parameters among COVID-19 Frontline Warriors Coronavirus disease 19 infection Online Sudarshan Kriya Yoga practice alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute Of Medical Sciences, Rishikesh India 2020-10-08 CTRI/2020/09/028086 Phase Not Applicable Not yet recruiting 1 43 Dr Monika Pathania 2020-09-30
Assessment of Knowledge, Attitude and Practice Towards COVID-19 Pandemic among Hospital Jengka Employees Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Jengka Hospital Malaysia 2020-09-29 2021-02-15 NMRR-20-2044-55325 Phase Not Applicable Not yet recruiting 1 4 Months Mrs. ZURIA IKAZIRA BINTI ZAKARIA 2020-09-30
Mitigation of COVID-19 Clusters in Malaysia Coronavirus disease 19 infection Seberang Jaya Hospital Malaysia 2020-09-24 2020-09-25 NMRR-20-2033-56605 Phase Not Applicable Status not specified 1 DR. MONICA A/P DANIAL 2020-09-30
Evaluation of Atypical imaging features on HRCT CHEST Coronavirus disease 19 infection HRCT alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kalinga Institute of Medical Sciences India 2020-10-20 CTRI/2020/09/028049 Phase Not Applicable Not yet recruiting 1 300 Dr Col Kamal Kumar Sen, Rohit Arora 2020-09-30
Homoeopathy management for covid 19 patients Coronavirus disease 19 infection homoeopathic medicine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Council for Research in Homeopathy Ministry of Ayush India 2020-10-05 CTRI/2020/09/028046 Phase Not Applicable Not yet recruiting 1 100 Dr Sushma Bhtanagar 2020-09-30