Last updated: Oct 27, 2020 - 02:00 GMT
| Ampligen in Chronic Fatigue Syndrome |
Chronic fatigue syndrome, Coronavirus disease 19 infection |
rintatolimod alone |
2,5-Oligoadenylate synthetase stimulator, Interferon type I receptor agonist, Ribonuclease stimulator, TLR-3 agonist |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
AIM ImmunoTech Inc |
|
US |
|
|
AMP 511, NCT00215813 |
Phase 3 Clinical |
Recruiting |
2 |
|
|
Ann Marie Coverly, Charles Lapp, MD, Charles W. Lapp, M.D., Daniel Peterson, M.D., Daniel Peterson, MD, Diane Young |
2020-10-15 |
| An open-label, prospective study to evaluate RLF-100 in patients admitted to an intensive care unit (ICU) with critical COVID-19 and respiratory failure |
Coronavirus disease 19 infection, Respiratory failure |
aviptadil (inhaled, sarcoidosis/acute lung injury/acute respiratory distress syndrome associated COVID-19), Relief Therapeutics Holding alone |
Adrenergic receptor antagonist, VIP receptor agonist |
|
NeuroRx Inc, Relief Therapeutics Holding AG |
|
|
|
|
|
Phase 2 Clinical |
Status not specified |
0 |
|
|
|
2020-10-26 |
| A trial to evaluate PGX-YBG for the treatment of patients with COVID-19 |
Coronavirus disease 19 infection |
PGX-YBG alone |
|
|
Ceapro Inc |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-10-26 |
| EAT COVID: An investigator initiated, randomized, Phase II clinical trial evaluating its eftilagimod alpha (“efti” or “IMP321”) in hospitalized patients with COVID-19 |
Coronavirus disease 19 infection |
eftilagimod alfa alone, standard care alone |
HLA class II antigen stimulator |
|
Immutep Ltd |
University Hospital Pilsen |
Czech Republic |
|
|
EAT COVID |
Phase 2 Clinical |
Recruiting |
1 |
|
110 |
Dr. Dalibor Sedlacek, Dr. Marek Nalos,, Martin Matejovic |
2020-10-26 |
| A phase Ib clinical study to assess ProTrans in the treatment of subjects with COVID-19 |
Coronavirus disease 19 infection |
ProTrans alone |
|
|
NextCell Pharma AB |
Karolinska Trial Alliance |
Sweden |
|
|
|
Phase 1b Clinical |
Planned |
1 |
|
9 |
Doctor Tomasz Oldak, Professor Dominique Farge, Professor Edvard Smith, Professor Farge, Professor Josefin Sundh |
2020-10-26 |
| SARS-CoV-2 (COVID-19) Immune Surveillance Among a Population Based Sample of Adults in Florida |
Coronavirus disease 19 infection |
SARS-CoV-2 antibody analysis alone, Weck-cel swab collection alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
H Lee Moffitt Cancer Center and Research Institute |
Merck Sharp & Dohme Corp |
US |
2020-10-09 |
2022-10-09 |
MCC-20635, NCT04596579 |
Phase Not Applicable |
Recruiting |
2 |
24 Months |
1200 |
Anna R Giuliano, PhD |
2020-10-25 |
| oXAKI-COV: Efficacy and Safety of a Highly Selective Semipermeable Membrane (AN69 oXiris) versus (Standard AN69) in COVID-19 |
Coronavirus disease 19 infection, Inflammatory disease, Renal injury |
AN69 oXiris alone, continuous renal replacement therapy alone, vasopressor therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Instituto Nacional de Ciencias Medicas y Nutricion |
|
Mexico |
2020-10-02 |
2022-03-30 |
NCT04597034, NMM-3401-20-20-1, oXAKI-COV |
Phase Not Applicable |
Recruiting |
1 |
17 Months |
35 |
Mauricio Arvizu-Hernández, MD, Olynka Vega Vega, MD, Olynka Vega-Vega, MD, Ricardo Correa Rotter, MD, Ricardo Correa-Rotter, MD |
2020-10-25 |
| Vitamin D3 Supplementation to Prevent Respiratory Tract Infections |
Coronavirus disease 19 infection, Respiratory tract infection |
vitamin D, Cooper alone |
|
Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The Cooper Health System |
|
|
2020-10-31 |
2021-11-30 |
20-455, NCT04596657 |
Phase Not Applicable |
Not yet recruiting |
0 |
13 Months |
2099 |
Noud van Helmond, MD |
2020-10-25 |
| Study to Evaluate Efficacy and Safety of 'Viracide' in the Management of Corona Virus Disease 2019 (COVID-19) |
Coronavirus disease 19 infection |
ViraCide alone, standard of care alone |
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
|
|
India |
2020-09-16 |
2021-01-30 |
NCT04596085, NS-VC-CT01-20 |
Phase Not Applicable |
Recruiting |
2 |
4 Months |
124 |
Dr Ninad Naik, MD(Ayurveda), Dr. A Gopal Rao, MD Medcine, Dr. A Gopal Rao, MD(Med), Dr.Mahir Abduldaim, Dr.Ninad Naik, MD(Ayurveda), Muralidhar Gudla, Niranjan Andhalkar, Sohal Pendse |
2020-10-25 |
| APCC-19: Chemoprevention Clinical Trial of COVID-19: Hydroxychloroquine Post Exposure Prophylaxis |
Coronavirus disease 19 infection |
hydroxychloroquine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
|
Farhat Hached University Hospital, Fattouma Bourguiba University Hospital |
Jordan |
2020-10-27 |
2021-01-31 |
APCC-19, APCC-19, NCT04597775 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
3 Months |
93 |
Amer A Amous, MD, Munir A Abu-Helalah, PhD, Munir Abu-Helalah, PHD, Wissem Hachfi, MD |
2020-10-24 |
| Predicting the role of resilience, reactance, social solidarity and positive schemas on Pandemic-related Anxiety |
Anxiety disorder, Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
LVR-Klinikum DüsseldorfKliniken der Heinrich-Heine-Universität Düsseldorf |
|
Germany |
2020-11-01 |
|
2020-1071, DRKS00023321 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
85 |
Milenko Kujovic |
2020-10-24 |
| Prevalence and Temporal Evolution of Chest Radiographic Findings in Filipino Patients with Coronavirus Disease 2019 (COVID-19) |
Coronavirus disease 19 infection |
chest radiographic findings alone |
|
|
University of the Philippines |
|
Philippines |
2020-05-15 |
2021-01-15 |
PHRR201012-003027 |
Phase not specified |
No longer recruiting |
1 |
8 Months |
|
Jarold P. Pauig, Johanna Patricia Adevoso-Cañal, Julian A. Santos, Rosanna E. Fragante |
2020-10-24 |
| The Knowledge, Attitudes and Practices of Resident Physicians in Southern Philippines Medical Center, Davao City Philippines towards COVID-19: a cross-sectional study |
Coronavirus disease 19 infection |
Knowledge levels, attitudes and practices alone |
|
|
Southern Philippines Medical Center |
|
Philippines |
2020-11-01 |
2020-12-01 |
PHRR201012-003017 |
Phase Not Applicable |
Not yet recruiting |
1 |
1 Month |
|
Gleno Lon Q. Llamera, Pilar Mynthia B. Vicente, Shera Elefante |
2020-10-25 |
| VTE-COVID-19: Non-invasive Prognostication of COVID-19 Patients by Use of Biomarkers in Exhaled Breath Condensate |
Coronavirus disease 19 infection, Lung injury, Respiratory insufficiency |
exhaled breath condensate analysis alone, metabolomics analysis alone, proteomics analysis alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Aalborg Universitetshospital |
Aarhus University Hospital Skejby |
Denmark |
2020-09-19 |
2021-10-01 |
ILG-VTE-COVID-19-2020, N-20200069, NCT04598620, VTE-COVID-19 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
50 |
Inger L Gade, MD, PhD, Lise T Elkjær |
2020-10-24 |
| Cytokine Storm Among Bangladeshi Patients With COVID-19 |
Coronavirus disease 19 infection, Inflammatory disease |
biological sampling alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry |
International Centre For Diarrhoeal Disease Research, Bangladesh |
|
Bangladesh |
2020-10-31 |
2021-06-30 |
ICDDR,B, NCT04598334 |
Phase Not Applicable |
Not yet recruiting |
1 |
8 Months |
75 |
Mohammod J Chisti, MBBS, PhD, Mohammod J Chisti, MBBS,PhD, Monira Sarmin, Monira Sarmin, MBBS, Monira Sarmin, MBBS, MCPS, Tahmeed Ahmed, MBBS, PhD |
2020-10-24 |
| Safety of Sofosbuvir/Daclatasvir in outpatients with COVID-19 |
Coronavirus disease 19 infection |
Sovodak, Fanavaran Rojan Mohaghegh Daru Co alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tehran University of Medical Sciences |
International Treatment Preparedness Coalition |
Iran |
2020-10-24 |
|
IR.TUMS.DDRI.REC.1399.024, IRCT20200128046294N3 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
|
50 |
Anahita Sadeghi, Neda Alijani, Shahin Merat |
2020-10-24 |
| AcNT-COVID19: Immune Responses to COVID-19; Isolation of Neutralizing Antibodies for Therapeutics and Vaccine |
Coronavirus disease 19 infection |
Blood sampling alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital, Grenoble |
Commissariat a l`Energie Atomique |
France |
2020-04-30 |
2021-09-30 |
2020-A00904-35, 38RC20.132, AcNT-COVID19, NCT04596098 |
Phase Not Applicable |
Recruiting |
2 |
17 Months |
120 |
Benjamin NEMOZ, PHD, Djamila DURIN, engineer, Pascal POIGNARD, PHD, Pierre AUDOIN, engineer |
2020-10-24 |
| Antiviral Activity and Safety of Remdesivir in Bangladeshi Patients With Severe Coronavirus Disease (COVID-19) |
Coronavirus disease 19 infection, Respiratory distress syndrome |
remdesivir alone, standard of care alone |
COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Beximco Pharmaceuticals Ltd |
|
Bangladesh |
2020-09-04 |
2021-01-31 |
BEX-06001, NCT04596839 |
Phase 2 Clinical |
Recruiting |
1 |
4 Months |
60 |
Dr. Md. Alimur Reza, Dr. Md. Alimur Reza, MBBS, MPH, Major General Md. Azizul Islam, Major General Md. Azizul Islam, MBBS, FCPS |
2020-10-24 |
| CAPTURE-2: Research and Evaluation of LumiraDx SARS-CoV-2 (COVID-19) Point of Care Ab Test |
Coronavirus disease 19 infection |
LumiraDx alone, SARS-CoV-2 Ab test alone |
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
LumiraDx UK Ltd |
|
US |
2020-08-20 |
2022-12-31 |
CAPTURE-2, NCT04597047, S-CLIN-PROT-0031 |
Phase Not Applicable |
Recruiting |
4 |
28 Months |
200 |
David Craig, Matthew Morgan, Melanie Hoppers, Vicki Kalen, William Simon |
2020-10-24 |
| NanoDxCoV19: Exploration of Feasability of Blood and Saliva Proteomic Analysis Through Harvesting by Silica Matrix |
Coronavirus disease 19 infection, Respiratory tract infection |
proteomic analysis alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital, Grenoble |
|
France |
2020-10-15 |
2021-12-31 |
38RC20.289, NCT04597216, NanoDxCoV19 |
Phase Not Applicable |
Recruiting |
1 |
14 Months |
200 |
olivier EPAULARD |
2020-10-24 |
| NICOVID-REA: Evaluation of the Efficacy of Nicotine Patches in SARS-CoV2 (COVID-19) Infection in Intensive Care Unit Patients |
Coronavirus disease 19 infection |
nicotine alone |
Nicotinic acetylcholine receptor agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assistance Publique Hopitaux de Paris |
|
|
2020-10-31 |
2021-10-31 |
2020-003723-42, APHP200537, NCT04598594, NICOVID-REA |
Phase 3 Clinical |
Not yet recruiting |
0 |
12 Months |
220 |
|
2020-10-24 |
| Expanded Access Study of Exebacase in COVID-19 Patients With Persistent MRSA Bacteremia |
Coronavirus disease 19 infection, Endocarditis, MRSA infection |
antistaphylococcal antibiotic therapy alone, exebacase alone |
Hydrolase stimulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
ContraFect Corp |
|
|
|
|
CF-301-107, NCT04597242 |
Phase Not Applicable |
Recruiting |
0 |
|
|
Medical Director, ContraFect |
2020-10-24 |
| Schools Transmission Study (COVID-19 and Scarlet Fever) |
Coronavirus disease 19 infection, Group A Streptococcus infection |
biological sampling alone |
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) |
Imperial College London |
Action Medical Research, National Institute for Health Research (NIHR) |
UK |
2017-09-01 |
2025-03-31 |
CPMS 37059, IRAS 225006, ISRCTN13773960 |
Phase Not Applicable |
Recruiting |
1 |
91 Months |
344 |
Mrs Kerri Hill-Cawthorne, Prof Sriskandan |
2020-10-24 |
| A study to assess safety and efficacy UNI-91103 in patients affected with covid-19 |
Coronavirus disease 19 infection |
UNI-91103 alone |
|
Healthy volunteers accepted |
UNION therapeutics |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
44 |
|
2020-10-24 |
| Evaluation of the Possible Vertical Transmission of SARS-CoV-2 Through Study of Amniotic Fluid and Chorionic Villi of Affected Pregnant Women for the COVID-19 |
Coronavirus disease 19 infection |
|
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fundacio Institut De Recerca De L'Hospital De La Santa Creu I Sant Pau |
|
Spain |
2020-08-08 |
2022-01-23 |
IIBSP-COV-2020-59, NCT04598347 |
Phase Not Applicable |
Recruiting |
1 |
17 Months |
225 |
Obdulia Alejos Abad, PhD, MD, Obdulia Alejos, MD |
2020-10-24 |
| A prospective study to evaluate the accuracy of Cue COVID-19 Test in the diagnosis of COVID-19 infection |
Coronavirus disease 19 infection |
Cue COVID-19 Test alone |
|
|
Mayo Clinic Foundation |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
|
|
2020-10-24 |
| A pivotal, phase III study of plitidepsin in patients with COVID-19, who require hospitalization |
Coronavirus disease 19 infection |
plitidepsin alone |
Elongation factor 1 alpha 2 modulator, VEGF-1 receptor modulator |
|
PharmaMar SA |
|
|
|
|
|
Phase 3 Clinical |
Planned |
0 |
|
|
|
2020-10-23 |
| A study of association of chest x-ray with clinical severity in hospitalized COVID-19 patients |
Coronavirus disease 19 infection, Hypoxia, Respiratory distress syndrome |
chest x-ray alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kasturba hospital, Manipal |
|
India |
2020-10-31 |
|
CTRI/2020/10/028525 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
300 |
Nandakrishna B |
2020-10-23 |
| >A phase III clinical trial of AT-527 to explore the potential use in patients outside of the hospital setting |
Coronavirus disease 19 infection |
AT-527 alone |
Hepatitis C virus NS5B polymerase inhibitor |
|
Atea Pharmaceuticals Inc, Roche Holding AG |
|
|
2021-03-31 |
|
|
Phase 3 Clinical |
Planned |
0 |
|
|
|
2020-10-23 |
| Hematological and biochemical abnormalities parameters in the severity of COVID-19 |
Coronavirus disease 19 infection |
tocilizumab alone |
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shree Krishna Hospital, pramukhswami medical college |
|
India |
2020-10-30 |
|
CTRI/2020/10/028523 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
200 |
Dr Abdulrahman Amer, Dr Hitesh Shah |
2020-10-23 |
| COSEVAST study: To study the relationship of COVID-19 severity with blood vessels |
Cardiovascular disease, Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
All India Institute of Medical Sciences Patna |
|
India |
2020-10-26 |
|
COSEVAST study, CTRI/2020/10/028489 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
75 |
Neeraj Kumar, Sanjeev Kumar |
2020-10-23 |
| RISEUP-PPD-COVID-19: Impact of COVID-19 Pandemic in Perinatal Mental Health |
Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder, Psychiatric disorder |
|
|
Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universidade do Minho |
Bar-Ilan University, European University Cyprus, Havre Hospital, Instituto Presbiteriano Mackenzie, Instituto de Investigacion Biomedica de Malaga, Instituto de Saúde Pública da Universidade do Porto (ISPUP), King's College London, Mount Carmel Health System, Universidad Nacional De Educación A Distancia (UNED), Universidad de Huelva, Universidade Católica Portuguesa - Ucp, University of Athens, University of Coimbra, University of Malta, University of Sofia |
UK, Turkey, Brazil, Malta, France, Israel, Bulgaria, Portugal, Chile, Cyprus, Greece, Albania, Spain |
2020-06-15 |
2021-06-15 |
NCT04595123, RISEUP-PPD-COVID-19, RISEUP-PPD-COVID-19 |
Phase Not Applicable |
Recruiting |
13 |
12 Months |
3900 |
Ana Mesquita, PhD, Ana Rita Carlos, Andry Christoforou, PhD, Angelique Picard, PhD, Camellia Hancheva, PhD, Claire Wilson, PhD, Eleni Vousoura, PhD, Emma Motrico, PhD, Erilda Ajaz, PhD, Ethel Felice, Dr, Pelin Dikmen-Yildiz, PhD, Rena Bina, PhD, Sandra M. Saldivia, PhD, Sara Dominguez, PhD, Vera Mateus, PhD |
2020-10-24 |
| The impact of COVID-19 pandemic on colorectal cancer therapy |
Colorectal tumor, Coronavirus disease 19 infection |
|
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
|
|
Japan |
2020-08-15 |
|
UMIN000042211 |
Phase Not Applicable |
No longer recruiting |
1 |
|
123 |
Mizuno Rei |
2020-10-26 |
| NETSCOV TRIAL: Role of blood cellular mechanism in severity of COVID-19 |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
All India Institute of Medical Sciences Patna |
|
India |
2020-10-26 |
|
CTRI/2020/10/028488, NETSCOV TRIAL |
Phase Not Applicable |
Not yet recruiting |
1 |
|
60 |
Abhyuday Kumar |
2020-10-23 |
| COVIDCOLLECT: Relationship Between Biological Profiles and Clinical Evolutions Within the Same Cluster COVID-19 |
Coronavirus disease 19 infection |
RT-PCR alone |
|
Healthy volunteers accepted |
University Hospital Clermont-Ferrand |
|
France |
2020-11-30 |
2022-02-28 |
2020-A02381-38, COVIDCOLLECT, NCT04597736, RBPH 2020 HENQUELL |
Phase Not Applicable |
Not yet recruiting |
1 |
15 Months |
100 |
Cécile Henquell, Céclie Henquell, Etienne Merlin, Lise LACLAUTRE, Lise Laclautre, Magali Vidal, Marc Berger, Olivier Lesens |
2020-10-23 |
| CEMS: To Study the safety of remdesivir in COVID-19 Patients |
Coronavirus disease 19 infection |
remdesivir alone |
COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
All India Institute of Medical Sciences Patna |
|
India |
2020-10-30 |
|
CEMS, CTRI/2020/10/028487 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Dr Aakanksha Priya, Dr Shruti Singh |
2020-10-23 |
| CONSERVE-HCW: Changes in Seroprevalence and Wellness Over Time in Healthcare Workers |
Coronavirus disease 19 infection |
bbott Architect SARS-CoV-2 IgG assay alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
St. Joseph's Hospital and Medical Center |
Chandler Regional Medical Center, Dignity Health, Mercy Gilbert Medical Center |
US |
2020-06-10 |
2021-12-30 |
20-510-157-66-21, CONSERVE-HCW, NCT04595175 |
Phase Not Applicable |
Recruiting |
1 |
18 Months |
2000 |
Andrea B. Garcia, MBA, Andrea Garcia, MBA, Brian Tiffany, Brian Tiffany, MD, PhD, Jennine Zumbuhl, RN, MSHA |
2020-10-23 |
| COVID-RT-01: Low Dose Radiation Therapy for Severe-Acute-Respiratory-Syndrome-Coronavirus-2 (SARS-CoV-2) |
Coronavirus disease 19 infection |
low dose radiation therapy (1 Gray) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Basel |
|
Switzerland |
2020-11-30 |
2021-11-30 |
2020-02047QU20PAPACHRISTOFILOU, COVID-RT-01, NCT04598581 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
22 |
Alexandros Papachristofilou, Dr. med., Martin Siegemund, Prof. Dr. med., Tobias Finazzi, Dr. med. |
2020-10-23 |
| LungMechCoV-19: Assessment of Lung Mechanics in COVID-19 Acute Respiratory Distress Syndrome |
Coronavirus disease 19 infection, Respiratory failure |
Impedance tomography alone, indirect calorimetry alone, right-heart catheterization alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Zurich |
|
|
2020-10-20 |
2021-12-31 |
2020-01999, LungMechCoV-19, NCT04597853 |
Phase Not Applicable |
Not yet recruiting |
0 |
14 Months |
25 |
Philipp K Buehler, MD |
2020-10-23 |
| FIPPS: Trial of financial incentives for preventing postpartum return to smoking |
Coronavirus disease 19 infection, Nicotine dependence |
financial incentive alone |
|
Female, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Of Stirling |
|
UK |
2018-02-01 |
2022-11-30 |
FIPPS, ISRCTN55218215, VERSION 6.0 |
Phase Not Applicable |
Recruiting |
5 |
58 Months |
900 |
Prof Ussher |
2020-10-24 |
| Treatment of SARS-CoV-2 Virus Disease (COVID-19) in Humans With Hemopurifier Device |
Acute lung injury, Coronavirus disease 19 infection, Multiple organ failure, Respiratory distress syndrome, Respiratory failure, Septic shock |
Hemopurifier alone, arteriovenous fistula treatment alone, double-lumen hemodialysis catheter alone, extracorporeal therapy alone, graft treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Aethlon Medical Inc |
|
|
2020-10-31 |
2021-08-31 |
AEMD-2020-02, NCT04595903 |
Phase Not Applicable |
Not yet recruiting |
0 |
10 Months |
40 |
Lisa Boswell, Timothy C Rodell, MD |
2020-10-23 |
| A clinical study to assess AZD-7442 in the treatment of subjects with COVID-19 |
Coronavirus disease 19 infection |
AZD-7442 alone |
COVID19 Spike glycoprotein inhibitor |
|
AstraZeneca plc |
Biomedical Advanced Research and Development Authority (BARDA) |
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
4000 |
|
2020-10-23 |
| Yoga for COVID-19 Patients with mild symptoms |
Coronavirus disease 19 infection, Respiratory tract infection |
Yoga modules intervention alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Mahatma Gandhi Memorial Medical College, Indore, Swami Vivekananda Yoga Anusandhana Samsthana Svyasa |
|
India |
2020-11-02 |
|
CTRI/2020/10/028486 |
Phase 1 Clinical |
Not yet recruiting |
1 |
|
50 |
Dr Satyapriya Maharana, Pragya Jain Shrimal |
2020-10-23 |
| Endoscopic Procedures of Children in the Normalization Process of Covid-19 Pandemic |
Coronavirus disease 19 infection, Gastrointestinal disease |
COVID-19 PCR test alone, chest radiography alone, endoscopy alone, thorax computed tomography alone |
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Tepecik Training and Research Hospital |
|
Turkey |
2020-06-01 |
2020-08-31 |
NCT04598256, TEPECIKTRH1 |
Phase Not Applicable |
Completed |
1 |
3 Months |
77 |
BETÜL AKSOY, MD, DİLEK YILMAZ ÇİFTDOĞAN, PROFESSOR, MAŞALLAH BARAN, PROFESSOR, YELİZ ÇAĞAN APPAK, MD, ŞENAY ONBAŞI KARABAĞ, MD |
2020-10-24 |
| Investigating the efficacy and safety of Myrtus inhalation spray in controlling the symptoms of patients with mild COVID-19 |
Coronavirus disease 19 infection |
Myrtus inhalation spray alone, routine treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Bagheiat-allah University of Medical Sciences |
|
Iran |
2020-07-22 |
|
IR.BMSU.REC.1399.159, IRCT20080901001165N63 |
Phase 3 Clinical |
No longer recruiting |
1 |
|
100 |
Gholamhosein Alishiri, Parisa Kianpour, Seyed Mohamad Javad Hosseini, Yunes Panahi |
2020-10-23 |
| Evaluation of short term outcomes of liver transplantation from COVID-19 positive deceased donors |
Acute liver failure, Coronavirus disease 19 infection |
liver transplantation alone |
|
|
Mashhad University of Medical Sciences |
|
Iran |
2020-10-01 |
|
IR.MUMS.REC.1399.442, IRCT20200928048867N1 |
Phase Not Applicable |
Recruiting |
1 |
|
10 |
Mohsen Aliakbarian, Mohsen Tafaghodi, Sara Saeidi Shahri |
2020-10-23 |
| CovidSat@Home: A randomized, controlled pilot trial investigating the feasibility and safety of monitoring patients with or at risk for cardiovascular disease who have symptoms suspected of COVID-19 by pulse oximetry at home |
Coronavirus disease 19 infection, Hypoxia |
home monitoring of blood oxygen levels alone, pulse oximeter alone, usual (primary) care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universitair Medisch Centrum Utrecht |
Dutch Heart Foundation |
|
2020-11-01 |
2021-06-01 |
CovidSat@Home, NL8954 |
Phase Not Applicable |
Not yet recruiting |
0 |
7 Months |
50 |
Dorien Zwart |
2020-10-25 |
| EPICS-14: Point of Care Influenza screening and SARS-CoV-2 (COVID-19) testing in the Emergency Department |
Coronavirus disease 19 infection, Influenza virus infection |
COVID-19 testing alone, Influenza A/B point-of-care screening test alone, cobas Liat system alone, multiplex real-time polymerase chain reaction test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Charite Universitaetsmedizin Berlin |
Roche Molecular Systems Inc |
Germany |
2019-12-17 |
|
DRKS00019207, EA2/204/19, EPICS-14, EPICS-14 |
Phase Not Applicable |
Recruiting |
1 |
|
3000 |
Martin Mockel |
2020-10-23 |
| Systematic Review - COVID19 |
Coronavirus disease 19 infection |
Corticosteroids therapy alone, tocilizumab alone |
|
|
Pulau Pinang Hospital |
|
Malaysia |
2020-11-01 |
2021-11-01 |
NMRR-20-2263-56296 |
Phase Not Applicable |
Status not specified |
1 |
12 Months |
|
DR Sivasangari Subramaniam, Lim Phei Ching |
2020-10-23 |
| ASTERIX: An observational study to identify sub-groups of COVID-19 patients based on their demographic, clinical and laboratory profile, and to determine if these sub-groups can be used to predict severity of disease and response to therapy |
Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia |
|
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
NHS Greater Glasgow and Clyde |
National Institute for Health Research (NIHR), Scottish Government Health and Social Care Directorates |
UK |
2020-04-01 |
2021-01-01 |
ASTERIX, CPMS 46231, IRAS 283151, ISRCTN66141262 |
Phase Not Applicable |
Recruiting |
2 |
9 Months |
600 |
Mrs Evans |
2020-10-23 |
| Relationships between physical activity during hospitalization and physical capacity after discharge from hospital in patients with COVID-19: a prospective, observational study |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Wakayama Medical University |
|
Japan |
2020-11-15 |
|
UMIN000042214 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
40 |
Masakazu Minetama, Tadashi Sumiya |
2020-10-23 |
| A Phase Ib clinical trial to evaluate the safety, tolerance and preliminary immunogenicity of different doses of a novel coronavirus pneumonia (COVID-19) mRNA vaccine in population aged 18 to 59 years |
Coronavirus disease 19 infection |
SARS-CoV-2 mRNA vaccine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Chinese Academy of Medical Military Sciences, Hangzhou Hospital of Traditional Chinese Medicine, Suzhou Abogen Biosciences |
|
China |
2020-10-28 |
2021-12-31 |
ChiCTR2000039212 |
Phase 1b Clinical |
Not yet recruiting |
1 |
14 Months |
1200 |
Lin Yuan, Shuyuan Yang |
2020-10-23 |
| Yoga for COVID-19 asymptomatic patients |
Coronavirus disease 19 infection |
Tele based yoga alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Swami Vivekananda Yoga Anusandhana Samsthana Svyasa |
|
India |
2020-11-02 |
|
CTRI/2020/10/028566 |
Phase 1 Clinical |
Not yet recruiting |
1 |
|
60 |
Dr Satyapriya Maharana, Pragya Jain Shrimal |
2020-10-23 |
| IND-02 for prevention against SARS-CoV-2 Infection: A Randomized, controlled study in moderate to high risk population |
Coronavirus disease 19 infection |
IND-02 alone |
ApoB editing catalytic polypeptide 3G modulator, HIV gp120 protein modulator |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Indus Biotech Pvt Ltd |
|
India |
2020-10-29 |
|
CTRI/2020/10/028547, IND02-NASAL-PROPHYLAXIS |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
5 |
|
258 |
Dr A Venkateshwar Rao, Dr Deepak B Varade, Dr Kapil Patwardhan, Dr Manish Rajak, Dr Nidhi Anand, Dr Prasad Thakurdesai, Dr Sonali Nirhali |
2020-10-26 |
| High-flow nasal cannula oxygen in adult patients of COVID-19 admitted to intensive care units. |
Coronavirus disease 19 infection |
igh-flow nasal cannula oxygen therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Lok Nayak Hospital |
|
India |
2020-10-28 |
|
CTRI/2020/10/028539 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
70 |
sukhyanti kerai |
2020-10-26 |
| Clinical trial of Ayurvedic Medicines in Patients with Asymptomatic and/or Mild Symptoms of COVID-19 |
Coronavirus disease 19 infection |
Chyawanprash alone, Immuncoction alone, Standard medicine therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
|
|
India |
2020-10-22 |
|
CTRI/2020/10/028537, MHC/CT/20-21/011 |
Phase 2 Clinical |
Not yet recruiting |
2 |
|
90 |
Dr Anurag Gupta, Prof NS Sengar |
2020-10-23 |
| Semen Analysis Changes in Covid-19 Positive patients |
Coronavirus disease 19 infection |
Semen analysis alone |
|
Healthy volunteers accepted, Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Assiut University |
|
Egypt |
2020-05-01 |
2020-10-15 |
NCT04595240, SEMEN ANALYSIS POST COVID-19 |
Phase Not Applicable |
Completed |
1 |
5 Months |
100 |
ahmed a abdel moniem, md, mostafa kamel abdel rahman abdel aal |
2020-10-22 |
| ADDIMTCOVID: Inspiratory Muscle Training in COVID-19 Patients |
Coronavirus disease 19 infection |
PowerBreathe KHP2 alone, endurance training alone, inspiratory muscle training alone, interval training alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fundação de Ensino e Pesquisa em Ciências da saude |
Conselho Nacional de Desenvolvimento Cientifico e Tecnologico - CNPq, Jbs Sa, University of Brasilia |
Brazil |
2020-11-01 |
2021-06-30 |
ADDIMTCOVID, CNPQ092020, NCT04595097 |
Phase Not Applicable |
Not yet recruiting |
1 |
8 Months |
120 |
Vinicius Maldaner, Vinicius Zacarias Maldaner da silva |
2020-10-23 |
| Irbesartan and Oseltamivir treatment of COVID-19 infection |
Coronavirus disease 19 infection |
irbesartan plus oseltamivir |
Angiotensin II AT-1 receptor antagonist, Exo-alpha sialidase inhibitor |
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Slagelse Hospital |
|
Denmark |
2020-09-16 |
|
2020-001610-38, JAGG2020-1 |
Phase 4 Clinical |
Recruiting |
1 |
|
80 |
|
2020-10-23 |
| Treatment and followup outcomes of gynecological cancer patients treated with radiation therapy during lockdown phase of COVID pandemic |
Cancer, Coronavirus disease 19 infection |
radiation therapy alone |
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tata Memorial Centre |
|
India |
2020-10-30 |
|
CTRI/2020/10/028571 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1500 |
Dr Supriya Chopra |
2020-10-23 |
| To study the effect of Vyaghradi Kashay tablet on COVID-19 patients |
Coronavirus disease 19 infection |
Vyaghradi Kashay alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Ministry of Ayush |
Ayurvedic and Unani Tibbia College |
India |
2020-11-05 |
|
CTRI/2020/10/028570 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
30 |
Dr Manoj Shamkuwar, Dr Nitin Jindal |
2020-10-23 |
| COVID-19: Study to Evaluate the Efficacy of COVID-19-0001-USR in Patients With Mild/or Moderate COVID-19 Infection in Outpatient |
Coronavirus disease 19 infection |
COVID-19-0001-USR alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
|
|
Colombia |
2020-11-02 |
2021-01-29 |
COVID-19, COVID19-0001-USR, NCT04595136 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
2 Months |
60 |
Carlos A Riveros, MD, Juan Jaller, MD |
2020-10-23 |
| Trends in suicide rates during the Covid-19 pandemic quarantine |
Coronavirus disease 19 infection, Suicide |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
UniversitätsKlinikum Leipzig |
|
Germany |
2020-06-24 |
|
272/20-ek, DRKS00022536 |
Phase Not Applicable |
Recruiting |
1 |
|
500 |
Daniel Radeloff |
2020-10-24 |
| Clinical Study to Evaluate the Effects of Disulfiram in Patients With Moderate COVID-19 |
Coronavirus disease 19 infection |
disulfiram (Antabuse) alone |
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
|
|
Brazil |
2020-10-31 |
2021-04-30 |
NCT04594343, SPR-001-201 |
Phase 2 Clinical |
Not yet recruiting |
1 |
6 Months |
200 |
Augusto Mota, MD/PhD, Wendy Cousin, PhD |
2020-10-24 |
| Dosing of Thromboprophylaxis and Mortality in Critically Ill COVID-19 Patients |
Bleeding, Coronavirus disease 19 infection, Respiratory failure, Thromboembolism |
dalteparin sodium alone, tinzaparin sodium alone |
Antithrombin III, Factor IIa antagonist, Factor Xa antagonist, Low molecular weight heparin |
|
Karolinska Institutet |
|
Sweden |
2020-03-01 |
2020-10-15 |
NCT04593654, THROMBOPROPHYLAXIS COVID-19 |
Phase Not Applicable |
Completed |
1 |
7 Months |
257 |
Sandra Jonmarker, MD |
2020-10-23 |
| Teledermatology during the COVID-19 pandemic: A retrospective descriptive study |
Acne vulgaris, Coronavirus disease 19 infection, Eczema, Psoriasis, Skin cancer, Skin infection, Urticaria, Vasculitis, Venous insufficiency |
|
|
|
Southern Philippines Medical Center |
|
Philippines |
2020-11-01 |
2020-12-01 |
PHRR201015-003037 |
Phase Not Applicable |
Recruiting |
1 |
1 Month |
|
Anna Cristina L. Cuenca, Jen-Christina Segovia, MD, Lalaine R. Visitacion, MD, FPDS |
2020-10-24 |
| Virgin Coconut Oil (VCO) as a Potential Adjuvant Therapy in COVID-19 Patients |
Coronavirus disease 19 infection, Viral pneumonia |
virgin coconut oil alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Gadjah Mada |
|
Indonesia |
2020-06-01 |
2020-12-31 |
002/05/2020, NCT04594330 |
Phase 2 Clinical |
Recruiting |
4 |
7 Months |
60 |
Desy NP, MD, Eko Purnomo, MD, PhD, surgeon, Ika Trisnawati, MD, MSc, internist, Nur R Ananda, MD, internist-pulmonologist, Paulus Wisnu, MD, pulmonologist |
2020-10-22 |
| Red cell antibody profile in Covid-19 |
Coronavirus disease 19 infection |
Direct antiglobulin test alone |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Seth GS Medical College |
|
India |
2020-11-01 |
|
CTRI/2020/10/028567 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
200 |
Dr Swarupa Nikhil Bhagwat |
2020-10-23 |
| Study of the Safety of Prophylactic Vaccination With Second Generation E1/E2B/E3-Deleted Adenoviral-COVID-19 in Normal Healthy Volunteers |
Coronavirus disease 19 infection |
recombinant bivalent second-generation adenovirus (hAd5) vector-delivered SARS-CoV-2 S + N protein vaccine (oral, COVID-19), ImmunityBio alone, recombinant bivalent second-generation adenovirus (hAd5) vector-delivered SARS-CoV-2 S + N protein vaccine (subcutaneous, COVID-19), ImmunityBio alone |
COVID19 Spike glycoprotein modulator, COVID19 nucleoprotein modulator |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
ImmunityBio Inc |
|
US |
2020-10-19 |
2021-11-19 |
NCT04591717, QUILT-COVID-19-HAD5-VACCINE |
Phase 1b Clinical |
Recruiting |
1 |
13 Months |
35 |
Deborah Fridman, Lennie Sender |
2020-10-24 |
| A pivotal, phase III, randomized, double-blind, placebo-controlled trial of an interferon-beta (IFN-beta), SNG-001 treatment in the treatment of patients hospitalized with COVID-19 |
Coronavirus disease 19 infection |
inhaled interferon beta (lung disorders/influenza), Synairgen alone |
Interferon beta ligand |
|
PAREXEL International |
Synairgen plc |
|
|
|
|
Phase 3 Clinical |
Planned |
0 |
|
900 |
|
2020-10-22 |
| Outcomes of Elective Colorectal Cancer Surgery During COVID 19 Pandemic: Implications for Cancer Care Policy |
Colorectal tumor, Coronavirus disease 19 infection |
Colorectal resection alone |
|
|
Sher-i-Kashmir Institute of Medical Sciences |
|
India |
2020-03-23 |
2020-10-22 |
73/2020 (SUPL 2), NCT04588909 |
Phase Not Applicable |
No longer recruiting |
1 |
7 Months |
100 |
ASIF MEHRAJ, Senior Resident, Nisar A Chowdri |
2020-10-24 |
| NET_COV: Assessment of Netosis During COVID-19, Under Treatment With Anakinra, an Interleukin-1 Receptor Antagonist |
Coronavirus disease 19 infection, Inflammatory disease |
anakinra alone |
Type I IL-1 receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Groupe Hospitalier Paris Saint-Joseph |
|
France |
2020-11-19 |
2021-06-30 |
NCT04594356, NET_COV, NET_COV |
Phase Not Applicable |
Not yet recruiting |
1 |
7 Months |
126 |
Gilles HAYEM, MD, Helene BEAUSSIER, PharmD, pHD, Sylvie CHOLLET MARTIN, MD |
2020-10-22 |
| This is a Phase I Study to Evaluate the Safety, Tolerability and Virology of CT-P59 in Patients With Mild Symptoms of Symptoms of Coronavirus Disease (COVID-19) |
Coronavirus disease 19 infection |
CT-P59 alone |
COVID19 Spike glycoprotein inhibitor, Moesin modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Celltrion Healthcare Co Ltd, Celltrion Inc |
|
South Korea |
2020-09-04 |
2020-12-23 |
2020-003165-19, CT-P59 1.2, NCT04593641 |
Phase 1 Clinical |
No longer recruiting |
1 |
3 Months |
18 |
|
2020-10-23 |
| Hydrogen-oxygen Gas Mixture Inhalation in Patients With Convalescent Coronavirus Disease 2019 (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
AMS-H-03 alone, hydrogen-oxygen gas alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Guangzhou Institute Of Respiratory Disease |
|
China |
2020-10-31 |
2021-12-31 |
AMS-H-03-101, NCT04594460 |
Phase 2 Clinical |
Not yet recruiting |
2 |
14 Months |
198 |
Wei-jie Guan, PhD |
2020-10-25 |
| Impact of COVID-19 on Pediatric Dental Practice In Egypt |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Cairo University |
|
Egypt |
2021-02-28 |
2022-01-31 |
NCT04592510, Y66CYYG6 |
Phase Not Applicable |
Not yet recruiting |
1 |
11 Months |
290 |
Adel El Bardissy, Fatma Essam El-Deen, Fatma Essam El-Deen Abdel Rahim, Shaimaa Sabry |
2020-10-22 |
| COVID-19 human challenge study |
Coronavirus disease 19 infection |
test vaccines alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs) |
Imperial College London, Open Orphan PLC |
UK Government, hVIVO plc |
UK |
|
|
|
Phase Not Applicable |
Planned |
1 |
|
|
|
2020-10-22 |
| MuCo: Mucosal Immunity Against SARS-CoV-2 Infection in COVID-19 Patients |
Coronavirus disease 19 infection |
biological sampling alone |
|
|
Radboud University |
|
Netherlands |
2020-03-26 |
2020-05-13 |
2020-6342, MuCo, NCT04590352, NL73418.091.20 |
Phase Not Applicable |
Completed |
1 |
1 Month |
187 |
Dimitri Diavatopoulos, Dr |
2020-10-23 |
| EMO-COVID: Hemostatic Profile in Patients Affected by COVID-19 |
Coronavirus disease 19 infection, Thrombosis |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ospedale Papa Giovanni XXIII |
|
Italy |
2020-03-25 |
2021-05-10 |
EMO-COVID, EMO-COVID-ASSTPG23, NCT04595110 |
Phase Not Applicable |
Recruiting |
1 |
13 Months |
400 |
ANNA FALANGA, Anna Falanga, MD, Laura Russo, BSc |
2020-10-23 |
| Propolis supplementation And Coronavirus |
Coronavirus disease 19 infection |
Propolis supplementation (Reyhan Naghsh Jahan Pharmaceutical Co) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Isfahan University of medical Sciences |
|
Iran |
2020-08-22 |
|
IR.MUI.MED.REC.1399.337, IRCT20200802048267N1 |
Phase 2 Clinical |
Recruiting |
1 |
|
80 |
Karim Sohrabi, Shaghayegh Haghjooy |
2020-10-23 |
| MRI-AIDED: MRI Changes of Acute Kidney Injury in COVID-19 |
Coronavirus disease 19 infection, Renal injury |
MRI scans alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospitals Of Derby and Burton NHS Foundation Trust |
NIHR Nottingham Biomedical Research Centre |
UK |
2020-10-07 |
2023-09-30 |
287571, MRI-AIDED, NCT04594291, UHDB/2020/077 |
Phase Not Applicable |
Recruiting |
1 |
35 Months |
60 |
Maarten Taal, Professor, Nicholas Selby, Professor |
2020-10-24 |
| Defining the COVID-19 Immunity Denominator in the Mekong: a Cross-Sectional Seroprevalence Study of SARS-CoV-2 in Healthy Volunteers |
Coronavirus disease 19 infection |
ELISA alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
National Institute of Allergy and Infectious Diseases |
National Institutes of Health Clinical Center |
Cambodia |
2020-10-27 |
2023-12-31 |
000083-I, 10000083, NCT04594395 |
Phase Not Applicable |
Recruiting |
2 |
38 Months |
2700 |
Jessica E Manning, M.D., Ly Sovann, Suon Seila, M.D. |
2020-10-23 |
| A propensity score matched, retrospective, cohort study to evaluate the effect of famotidine on the clinical outcomes of hospitalized patients with COVID-19 |
Coronavirus disease 19 infection |
famotidine alone, proton pump inhibitors alone |
Histamine H2 receptor antagonist |
|
Columbia University |
|
US |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
1620 |
|
2020-10-22 |
| A late stage clinical trial of intranasal CodaVax-COVID for the prevention of Covid-19 |
Coronavirus disease 19 infection |
CodaVax-COVID alone |
|
|
Bharat Biotech International Ltd, Serum Institute of India Ltd |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-10-22 |
| COVIDWHELD: Improving Wellbeing and Health for Care Home Residents During COVID-19 |
Coronavirus disease 19 infection, Dementia |
COVID WHELD alone |
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Exeter University |
Alzheimers Society, King's College London, London School of Economics and Political Science, University of East Anglia, University of Hull |
|
2020-11-20 |
2022-01-01 |
20-21-10, COVIDWHELD, NCT04590469 |
Phase Not Applicable |
Not yet recruiting |
0 |
13 Months |
2880 |
Clive Ballard, MD, Clive G Ballard, MD, Dag Aarsland, MD |
2020-10-24 |
| MyeloidCovid: Myeloid Cells in Patients With COVID-19 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
blood sampling alone, nasal brushing alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Assistance Publique Hopitaux de Paris |
INSERM |
India |
2020-11-01 |
2023-11-01 |
2020-A02700-39, APHP201138, MyeloidCovid, NCT04590261 |
Phase Not Applicable |
Not yet recruiting |
1 |
36 Months |
120 |
Marie BENHAMMANI-Godard, Pierre-Régis Burgel, MD, PhD |
2020-10-23 |
| Study to Assess the Safety, Tolerability, and Pharmacokinetics of HFB-30132A Against COVID-19 in Healthy Adults |
Coronavirus disease 19 infection |
HFB-30132A alone |
Angiotensin converting enzyme 2 inhibitor, COVID19 Spike glycoprotein inhibitor |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
HiFiBio |
|
US |
2020-10-31 |
2021-07-31 |
HFB30132A-101, NCT04590430 |
Phase 1 Clinical |
Recruiting |
1 |
9 Months |
24 |
Francisco Adrian, Kari LaSalvia, Leela Vrishabhendra, MD |
2020-10-24 |
| COGCOV: The COGCOV Study in ICU Patients |
Cognitive disorder, Coronavirus disease 19 infection, Neurological disease |
Neurocognitive assessment alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ziekenhuis Oost-Limburg |
|
Belgium |
2020-10-07 |
2021-02-28 |
COGCOV, COGCOV, NCT04593069 |
Phase Not Applicable |
Recruiting |
1 |
4 Months |
60 |
Dieter Mesotten, MD, Elly Vandermeulen, Elly Vandermeulen, PhD |
2020-10-24 |
| Evaluating an Online Wellness Intervention for Indian College Students |
Anxiety disorder, Coronavirus disease 19 infection, Depression |
Common Elements Toolbox alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Pennsylvania |
|
|
2020-10-19 |
2021-06-30 |
843879, NCT04592588 |
Phase Not Applicable |
Not yet recruiting |
0 |
8 Months |
300 |
|
2020-10-24 |
| A retrospective, cross-sectional study to evaluate the lopinavir/ritonavir and interferon combination therapy effects on shortening the duration of viral shedding in COVID-19 patients |
Coronavirus disease 19 infection |
interferon-gamma plus lopinavir + ritonavir |
HIV protease inhibitor |
|
Anhui Medical University |
|
China |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
181 |
|
2020-10-22 |
| Testing Multiple Behavioral Science Strategies to Increase Flu-Shot Rates at a Large Retail Pharmacy |
Coronavirus disease 19 infection, Influenza virus infection |
flu shot text messages alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Pennsylvania |
|
US |
2020-09-25 |
2020-12-31 |
843523-TRIAL B, NCT04590066 |
Phase Not Applicable |
No longer recruiting |
1 |
3 Months |
1200000 |
|
2020-10-23 |
| ACROCOVID: Clinical and Mechanistic Study of Patients (With COVID-19 or Not) With a Recent Acrosyndrome |
Coronavirus disease 19 infection |
blood sampling alone, skin biopsy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assistance Publique Hopitaux de Paris |
Cochin Institute |
France |
2020-10-31 |
2020-12-31 |
ACROCOVID, APHP200884, NCT04590209, N° IDRCB 2020-A0181336 |
Phase Not Applicable |
Not yet recruiting |
1 |
2 Months |
25 |
Marie Benhammani-Godard, Nicolas Dupin, MD, PhD, Sélim Aractingi, MD, PhD |
2020-10-24 |
| PRONE-COVID: Prone Position to Improve Oxygenation in COVID-19 Patients Outside Critical Care |
Coronavirus disease 19 infection, Viral pneumonia |
Prone positioning alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cambridge University Hospitals NHS Foundation Trust |
|
UK |
2020-09-03 |
2021-06-30 |
284061, NCT04589936, PRONE-COVID |
Phase Not Applicable |
Recruiting |
1 |
9 Months |
56 |
Akhilesh Jha, Andrew Ying, Celine Goh, Chen Zhang, Fangyue Chen, Iain Goodhart, Jonathan Fuld, Kate Fitzpatrick, Marie Fisk, Sam Mann |
2020-10-23 |
| Using Telemedicine to Optimize Teamwork and Infection Control of Critical and Highly-infectious Patients in an Emergency Department |
Coronavirus disease 19 infection |
telemedicine based communication alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Taiwan University Hospital |
|
Taiwan |
2020-10-10 |
2021-10-30 |
202007114RINA, NCT04591873 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
100 |
Chien-Hao Lin, MD |
2020-10-24 |
| An observational, longitudinal, prospective cohort study on the predictive factors for cardiac conduction abnormalities with hydroxychloroquine-containing combinations for COVID-19 |
Cardiovascular disease, Coronavirus disease 19 infection |
Variable regimens including azithromycin , hydroxychloroquine , lopinavir + ritonavir |
HIV protease inhibitor |
|
Hospital General Universitario De Elche |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
105 |
|
2020-10-22 |
| A clinical trial of plasma-derived anti-SARS-CoV-2 IgG (COVID-19), Kedrion Biopharma/Kamada in the treatment of patients with COVID-19 infection |
Coronavirus disease 19 infection |
plasma-derived anti-SARS-CoV-2 IgG (COVID-19), Kedrion Biopharma/Kamada alone |
|
|
Kamada Ltd |
|
US |
|
|
|
Phase Not Applicable |
Planned |
1 |
|
|
|
2020-10-22 |
| ARCTIC: Aerosolized Inhaled Adenosine Treatment in Patients With Acute Respiratory Distress Syndrome (ARDS) Caused by COVID-19 |
Blood clotting disorder, Coronavirus disease 19 infection, Lung inflammation, Respiratory distress syndrome, Respiratory tract infection |
Aerogen nebulizer alone, adenosine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Florida |
|
US |
2020-12-31 |
2022-12-31 |
ARCTIC, IRB202002127, NCT04588441, OCR39505 |
Phase 2 Clinical |
Not yet recruiting |
1 |
24 Months |
30 |
Amy Gunnett, Bruce Spiess |
2020-10-23 |
| MAOi-COV19: Impact of a Monoamine Oxidase Inhibitor on the Phenotype of Blood Mononucleated Cells in Patients With COVID-19 |
Coronavirus disease 19 infection |
phenelzine (Nardil) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assistance Publique Hopitaux de Paris |
|
France |
2020-11-30 |
2021-11-30 |
2020-A02398-31, APHP200989, MAOi-COV19, NCT04590222 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
80 |
Katia BOURDIC, Olivier LAMBOTTE, Olivier LAMBOTTE, Prof |
2020-10-23 |
| Expressive Writing for COVID-19 Resilience |
Acute stress disorder, Coronavirus disease 19 infection, Depression |
virtually-delivered expressive writing alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Duke University |
|
US |
2020-05-26 |
2020-08-17 |
NCT04589104, PRO00105575 |
Phase Not Applicable |
Completed |
1 |
2 Months |
63 |
Oliver Glass, PhD |
2020-10-21 |
| Supporting Family Members With Severe Grief Reaction During the COVID-19 Pandemic |
Coronavirus disease 19 infection, Psychiatric disorder |
Bereavement Virtual Support alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ottawa Hospital Research Institute |
|
Canada |
2020-11-01 |
2022-01-01 |
20200653-01H, NCT04588415 |
Phase Not Applicable |
Not yet recruiting |
1 |
14 Months |
200 |
Antoine Przybylak-Brouillard, Peter Lawlor |
2020-10-21 |
| COVID-19-DM: The Effect of COVID-19 on Diabetes Mellitus |
Coronavirus disease 19 infection, Diabetes mellitus |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Usak University, Turkey |
|
Turkey |
2020-03-20 |
2020-11-01 |
COVID-19-DM, NCT04592055, UU-DM002 |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
500 |
Cevdet Duran, Cevdet Duran, Prof |
2020-10-23 |
| ACTIV-1 IM: Immune Modulators for Treating COVID-19 |
Coronavirus disease 19 infection |
Variable regimens including abatacept , cenicriviroc , infliximab , remdesivir |
CCR2 chemokine antagonist, CCR5 chemokine antagonist, COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, Cytotoxic T-lymphocyte protein-4 stimulator, RNA polymerase modulator, T cell surface glycoprotein CD28 inhibitor, TNF alpha ligand inhibitor, TNF binding agent |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Duke University |
Biomedical Advanced Research and Development Authority (BARDA), Duke Clinical Research Institute, Fisher Bioservices, National Center For Advancing Translational Sciences, National Institutes of Health, Syneos Health Inc, Technical Resources International |
US |
2020-10-31 |
2021-09-30 |
ACTIV-1 IM, NCT04593940, PRO00106301 |
Phase 3 Clinical |
Recruiting |
2 |
11 Months |
2190 |
Cameron Wolfe, Daniel K Benjamin, MD, PhD, Jane O'Halloran, Lori Hudson, PhD, Theresa Jasion, MS, William G. Powderly |
2020-10-24 |
| A phase II clinical study to assess Nylexa in the treatment of patients with COVID-19 |
Coronavirus disease 19 infection |
mercaptamine (parenteral, COVID-19), NovaBiotics alone |
|
|
NovaBiotics Ltd |
Technology Strategy Board |
|
|
|
|
Phase 2 Clinical |
Planned |
0 |
|
|
|
2020-10-21 |
| A case-report study in the evaluation of FDG-PET/CT in a patient with COVID-19 |
Coronavirus disease 19 infection |
18F-FDG alone, PET/CT alone, albumin alone, budesonide alone, hydroxychloroquine hydrochloride alone, interferon alone |
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Zhengzhou University |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
1 |
|
2020-10-23 |
| FaST-1: Furosemide as Supportive Therapy for COVID-19 Respiratory Failure |
Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia |
nebulized furosemide alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Queen's University |
University Health Network Toronto |
Canada |
2020-10-19 |
2021-10-01 |
FAST-1, FaST-1, NCT04588792 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
4 |
11 Months |
640 |
Dave Maslove, MD, Gordon Boyd, MD, HT Wand, MD, John Muscedere, MD, Oleksa Rewa, MD, Osama Loubani, MD, Stephanie Sibley, MD, Tracy Boyd |
2020-10-23 |
| Mindfulness to Mitigate Psychological Threat and Improve Engagement and Learning in Introductory Physics Courses |
Coronavirus disease 19 infection, Psychiatric disorder |
Mindfulness Training alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Pittsburgh |
James S McDonnell Foundation, National Science Foundation |
US |
2020-10-12 |
2022-12-31 |
NCT04589377, STUDY19050258 |
Phase Not Applicable |
Recruiting |
1 |
26 Months |
150 |
Brian Galla, PhD, Sara Jahanian, BS, Timothy Nokes-Malach, PhD |
2020-10-21 |
| The Peer-Delivered "Mind. Body. Voice." Program for High School Women (Mbv) - Remote |
Coronavirus disease 19 infection, Eating disorder |
mind, body, voice program alone |
|
Healthy volunteers accepted, Female |
University of Colorado |
|
US |
2020-10-09 |
2031-05-31 |
18-0007-03, NCT04591912 |
Phase Not Applicable |
Recruiting |
1 |
127 Months |
140 |
Bernadette Park, PhD, Gavin Bell, BA, Leah Pena Teeters, PhD, Leah Teeters, PhD, Sona A Dimidjian, PhD, Sona Dimidjian |
2020-10-21 |
| COCO-LATE: Late Clinical Events Associated With COVID-19 Infection |
Coronavirus disease 19 infection |
Biocollection alone, Follow-up visit alone, Questionnaire alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier de Tourcoing |
|
French Guiana, France |
2020-10-31 |
2022-08-31 |
COCO-LATE, NCT04591613, RIPH_2020_09 |
Phase Not Applicable |
Not yet recruiting |
17 |
22 Months |
1000 |
Clara FLATEAU, Cédric JOSEPH, David CHIRIO, Delphine POITRENAUD, Dominique SALMON, Elisabeth BOTELHO-NEVERS, François GOEHRINGER, Louis BERNARD, Marie GOUSSEFF, Marie PICHENOT, Nicolas VIGNIER, Olivier ROBINEAU, Olivier ROBINEAU, MD PhD, Reda CHIKOUCHE, Solange TREHOUX, PhD, Sophie PANAGET, Vincent DUBEE, Xavier LESCURE |
2020-10-23 |
| Dulce Digital-COVID Aware (DD-CA) Discharge Texting Platform for US/Mexico Border Hispanics With Diabetes + COVID-19 |
Coronavirus disease 19 infection, Non-insulin dependent diabetes |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Scripps Whittier Diabetes Institute |
National Institute of Diabetes, Digestive and Kidney Diseases |
US |
2020-11-01 |
2021-08-31 |
3R01DK112322-05S1, 3R01DK112322-05S1, NCT04591015 |
Phase 3 Clinical |
Not yet recruiting |
1 |
10 Months |
172 |
Athena Philis-Tsimikas, MD |
2020-10-22 |
| The Effect of Clear Masks in Improving Patient Relationships |
Coronavirus disease 19 infection |
Transparent mask alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of North Carolina |
|
US |
2020-09-03 |
2020-12-31 |
20-2229, NCT04595695 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
100 |
Ian Kratzke, MD, Ian M Kratzke, MD |
2020-10-23 |
| COVID-19-PE: Pulmonary Embolism and COVID-19 |
Coronavirus disease 19 infection, Lung embolism |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Usak University, Turkey |
|
Turkey |
2020-03-01 |
2020-12-01 |
COVID-19-PE, NCT04590378, UU-PE001 |
Phase Not Applicable |
Recruiting |
1 |
9 Months |
600 |
Barış Sevinç, M.D., Canan Akkus, M.D., Cevdet Duran, M.D., Cevdet Duran, Prof., Hakan Yilmaz, M.D. |
2020-10-22 |
| Safety and Efficacy of Hydroxychloroquine for the Treatment and Prevention of Coronavirus Disease 2019 (COVID-19) Caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) |
Coronavirus disease 19 infection, Injury |
elderberry intake alone, Variable regimens including N-acetylcysteine , azithromycin , hydroxychloroquine , quercetin , vitamin C , vitamin D3 , zinc |
|
Healthy volunteers accepted |
International Brain Research Foundation Inc |
|
US |
2020-11-30 |
2021-12-31 |
CTP-HCQ-COVID19, NCT04590274 |
Phase 1 Clinical |
Not yet recruiting |
1 |
13 Months |
5000 |
Philip DeFina, PhD |
2020-10-24 |
| COVID-RASi: The COVID-RASi Trial (COVID-19) |
Cardiovascular disease, Coronavirus disease 19 infection |
Angiotensin II Receptor Blockers alone, Angiotensin converting enzyme inhibitor alone, renin-angiotensin system inhibitors alone |
|
Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ottawa Heart Institute Research Corp |
|
Canada |
2020-10-30 |
2022-08-31 |
COVID-RASi, CTO-3212, NCT04591210 |
Phase 3 Clinical |
Not yet recruiting |
1 |
22 Months |
1155 |
Ermina Moga, Peter Liu, MD |
2020-10-22 |
| COVID-19 and Lung Ultrasound Utility |
Coronavirus disease 19 infection |
Butterfly iQ system alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
|
|
Canada |
2020-09-15 |
2021-09-30 |
0001, NCT04591158 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
100 |
William Cherniak, MD, MPH |
2020-10-22 |
| Remotely Delivered Programs Targeting COVID-19 Stress-Related Depression and Substance Use |
Acute stress disorder, Alcoholism, Anxiety disorder, Coronavirus disease 19 infection, Depression, Drug dependence |
CHAMindWell alone, Internet Cognitive Behavioral Therapy alone, Mindfulness Based Cognitive Therapy for Resilience During COVID-19 alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Cambridge Health Alliance |
National Center for Complementary and Integrative Health, Pennsylvania State University |
US |
2020-11-01 |
2022-11-01 |
3R33AT010125-03S1, CHA-IRB-1141/05/20, NCT04595084 |
Phase Not Applicable |
Not yet recruiting |
1 |
24 Months |
240 |
Carl Fulwiler, MD, Farah Samawi, Gabriella Conversano, Zev Schuman-Olivier, MD |
2020-10-23 |
| Maternal Telemental Health Interventions in Response to Covid-19*(CoronaVirus) |
Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression, Phobia |
Low-Intensity Psychosocial Interventions through Telemental health alone |
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Hamad Medical Corp |
|
Qatar |
2020-11-30 |
2022-02-28 |
MRC-05-087, NCT04594525 |
Phase Not Applicable |
Not yet recruiting |
1 |
15 Months |
58 |
|
2020-10-22 |
| COVID-19 Burnout Study |
Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection |
Mindfulness Based Intervention alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Health Network Toronto |
|
|
2020-11-01 |
2021-07-01 |
20-5678, NCT04594278 |
Phase Not Applicable |
Not yet recruiting |
0 |
8 Months |
100 |
|
2020-10-22 |
| VGV: A 3-month Cycle of Virtual Guided Tours to Promote Health in Older Community Members in a Context of COVID-19 Induced Social Isolation: a Pilot Study |
Coronavirus disease 19 infection, Muscle weakness |
Museum virtual guided tours alone |
|
Healthy volunteers accepted, Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sir Mortimer B Davis Jewish General Hospital |
|
Canada |
2021-01-04 |
2021-07-04 |
2021-2604, NCT04593433, VGV |
Phase Not Applicable |
Not yet recruiting |
1 |
6 Months |
40 |
Olivier Beauchet, MD |
2020-10-23 |
| GLS-1027 for the Prevention of Severe Pneumonitis Caused by SARS-CoV-2 Infection |
Coronavirus disease 19 infection, Viral pneumonia |
GLS-1027 alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
GeneOne Life Science Inc |
|
|
2020-11-30 |
2021-11-30 |
GLS27-005, NCT04590547 |
Phase 2 Clinical |
Not yet recruiting |
0 |
12 Months |
132 |
Medical Monitor, Project Manager |
2020-10-22 |
| PRISM: COVID-19: Pediatric Research Immune Network on SARS-CoV-2 and MIS-C |
Coronavirus disease 19 infection, Inflammatory disease |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
National Institute of Allergy and Infectious Diseases |
Autoimmunity Centers of Excellence |
US |
2020-10-31 |
2022-04-30 |
DAIT PRISM-01, NCT04588363, NIAID CRMS ID#: 38772, PRISM |
Phase Not Applicable |
Not yet recruiting |
21 |
18 Months |
250 |
Charles E. Canter, MD, Ekemini Akan Ogbu, MBBS, MSc, Emily Wasserman, MD, MS, Hayley Gans, MD, James B. Schneider, MD, James D. Wilkinson, MD, MPH, Joseph Rossano, MD,MS,FAAP,FACC, Karen P. Acker, MD, Lara A. Danziger-Isakov, MD, MPH, Leigh M. Howard, MD, MPH, Lisa F. Imundo, MD, Maria T. Thanjan, MD, Marian G. Michaels,, MD, MPH, Moshe Arditi, MD, Nadine F. Choueiter, MD, Natasha B Halasa, MD, MPH, Natasha Ruth, MD, MS, Octavio Ramilo, MD, Paul F. Kantor, MBBCh,MSc,FRCPC, Pramod Narula, MD, Rakesh Singh, MD, Rana Chakraborty, MD, DPhil, Steven A. Webber, MBChB, MRCP, William T. Mahle, MD |
2020-10-23 |
| This is a Phase I Clinical Trial to Evaluate the Safety, Pharmacokinetics, and Immunogenicity of ADM-03820, a Monoclonal Antibody Cocktail Being Tested for the Treatment and Prevention of COVID-19 |
Coronavirus disease 19 infection |
SARS-CoV-2 monoclonal antibodies (COVID-19), Ology/ VUMC alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Ology Bioservices Inc |
|
US |
2020-11-16 |
2021-08-30 |
ADM03820-001, NCT04592549 |
Phase 1 Clinical |
Not yet recruiting |
2 |
9 Months |
40 |
Angie Kimbler, Cassandra C Key, MD, Jonathan P Wilson, DO |
2020-10-22 |
| Study to Evaluate the Safety, Tolerability and Immunogenicity of an RNA Vaccine Candidate Against COVID-19 in Healthy Japanese Adults |
Coronavirus disease 19 infection |
BNT-162b2 alone |
COVID19 Spike glycoprotein modulator |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Japanese Ancestry |
BioNTech SE |
Pfizer Inc |
Japan |
2020-10-20 |
2021-11-30 |
C4591005, NCT04588480 |
Phase 1/Phase 2 Clinical |
Recruiting |
2 |
13 Months |
160 |
Pfizer CT.gov Call Center |
2020-10-22 |
| Measurement of IL-6 and Secondary Inflammatory Markers Before and After Therapeutic Plasma Exchange (TPE) in Hospitalized Patients |
Acute lung injury, Coronavirus disease 19 infection, Respiratory distress syndrome |
therapeutic plasma exchange alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Larkin Community Hospital |
|
US |
2020-09-11 |
2021-08-30 |
LCH-1-092020, NCT04592705 |
Phase 1 Clinical |
Recruiting |
1 |
11 Months |
10 |
Michael Talalaev, D.O. |
2020-10-21 |
| To Evaluate the Safety, Tolerability and Pharmacokinetic Properties of DWRX-2003 |
Coronavirus disease 19 infection |
repositioned niclosamide (refractory lung disease/COVID-19), Daewoong Pharmaceutical/Institut Pasteur Korea alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Daewoong Pharmaceutical Co Ltd |
Novotech (Australia) Pty Ltd |
|
2020-10-19 |
2021-06-30 |
DW_DWJ1516101_AUSTRALIA, NCT04592835 |
Phase 1 Clinical |
Not yet recruiting |
0 |
8 Months |
24 |
|
2020-10-23 |
| Effectiveness of Ivermectin and Doxycycline on COVID-19 Patients |
Coronavirus disease 19 infection |
Mechanical ventilation alone, Oxygen therapy/ C-Pap alone, Variable regimens including Vitamin C , Vitamin D3 , Zinc , acetaminophen , azithromycin , dexamethasone , doxycycline (Doxycin) , ivermectin , methylprednisolone |
Chloride channel modulator |
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Alkarkh Health Directorate-Baghdad |
|
Iraq |
2020-07-01 |
2020-10-14 |
IVM-DOX, NCT04591600 |
Phase 1/Phase 2 Clinical |
Completed |
1 |
3 Months |
140 |
Ahmed Sahib Abdulamir |
2020-10-22 |
| Study of Multiple Candidate Agents for the Treatment of COVID-19 in Hospitalized Patients |
Coronavirus disease 19 infection |
Standard of care alone, apremilast alone |
PDE 4 inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Amgen Inc |
|
|
2020-10-26 |
2021-07-13 |
2020-002594-10, COV-01, NCT04590586 |
Phase 3 Clinical |
Not yet recruiting |
0 |
8 Months |
700 |
Amgen Call Center |
2020-10-21 |
| Seroprevalence of SARS CoV-2 infections/Covid-19 in blood donors and patients of the University Hospitals in Leipzig |
Coronavirus disease 19 infection |
|
|
|
Institut für Virologie, Universitätsklinikum Leipzig |
|
Germany |
2020-06-20 |
|
147/20-ek, DRKS00023364 |
Phase Not Applicable |
Recruiting |
1 |
|
2000 |
Christian Jassoy |
2020-10-21 |
| Evaluation the effect of virtual pulmonary rehabilitaion on covid 19 patients |
Coronavirus disease 19 infection |
Breathing exercise alone, Virtual pulmonary rehabilitation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Shiraz University of Medical Sciences |
|
Iran |
2020-10-20 |
|
IR.SUMS.MED.REC.1399.364, IRCT20200930048892N1 |
Phase Not Applicable |
Recruiting |
3 |
|
70 |
Abbas Rezaeian zade, Fariba Erfani, Parnian Nikmanesh, Seyed Mohammad Kazem Tadayyon, Seyed Rouhollah Mousavi |
2020-10-21 |
| Abdominal CT scan findings in patients with COVID-19 |
Coronavirus disease 19 infection |
abdominal CT scan alone |
|
|
Philippine General Hospital |
|
Philippines |
2020-08-15 |
2020-09-18 |
PHRR201015-003026 PHRR201015-003026 |
Phase Not Applicable |
Completed |
1 |
1 Month |
|
Gerard Eastdon Truadio D. Ochoco, MD |
2020-10-21 |
| SPARCOL: SuPAR in Adult Patients With COVID-19 |
Coronavirus disease 19 infection |
ELISA assay alone, suPARnostic kit (ViroGates) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Thessaly |
|
Greece |
2020-10-11 |
2020-12-10 |
NCT04590794, SPARCOL, UTHDA-AC03 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
500 |
Athanasios Chalkias, PhD, Barbara Boutsis, Mrs, Eleni Laou, PhD |
2020-10-24 |
| CoV-Early: Early Convalescent Plasma Therapy for High-risk Patients With COVID-19 in Primary Care |
Coronavirus disease 19 infection |
convalescent plasma alone |
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Erasmus University Medical Center Rotterdam |
Leiden University Medical Center, Sanquin Plasma Products B.V., The Netherlands Organisation for Health Research and Development |
Netherlands |
2020-10-12 |
2023-11-01 |
CoV-Early, NCT04589949, NL74972.078.20 |
Phase 3 Clinical |
Recruiting |
11 |
36 Months |
690 |
Arvind Gharbharan, MD, Bart Rijnders, MD, PhD, Carlijn Jordans, MD, Casper Rokx, MD, PhD, D. Postma, MD, PhD, E. Jong, MD, PhD, Elana van Leeuwen, MD, PhD, Faiz Karim, MD, PhD, I Ludwig, MD, JJ Zwaginga, MD/PhD, L. Kampschreur, MD, PhD, R.W. van Etten, MD, PhD, Robert-Jan Hassing, MD, PhD, Robin Soetekouw, MD |
2020-10-21 |
| Development of a risk prediction model for people with diabetes and COVID-19 in Scotland |
Coronavirus disease 19 infection, Diabetes mellitus |
risk prediction model alone |
|
|
|
|
UK |
2020-04-06 |
2020-07-31 |
ISRCTN45562523, PBPP REF. 1617- 0147 |
Phase Not Applicable |
Completed |
1 |
3 Months |
5782649 |
Prof Colhoun |
2020-10-22 |
| COVID-19-DM2: The Effect of Diabetes Mellitus on the Prognosis of Patients With COVID-19 |
Coronavirus disease 19 infection, Diabetes mellitus |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Usak University, Turkey |
|
Turkey |
2020-03-20 |
2020-11-01 |
COVID-19-DM2, NCT04591704, UU-DM003 |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
2000 |
Cevdet Duran |
2020-10-21 |
| Evaluation of the effect of Tofacitinib in COVID-19 patients |
Coronavirus disease 19 infection |
Rhofanib (Alvand Nanotechnology Company) alone |
|
|
Iran University of Medical Sciences |
|
Iran |
2020-08-21 |
|
IR.IUMS.FMD.REC.1399.329, IRCT20200531047619N1 |
Phase 3 Clinical |
Recruiting |
1 |
|
10 |
Seyed Abbas Motavalian, Simin Almasi |
2020-10-21 |
| ICE-COVID: Iota-carrageenan Nasal Spray COVID-19 Prophylaxis for Healthcare Professionals |
Coronavirus disease 19 infection |
Coldamaris plus iota-carrageenan (intranasal, H1N1 influenza), Marinomed |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Swansea University, Wales |
Abertawe Bro Morgannwg University Health Board, Cardiff University, Marinomed Biotechnologie GmbH, Walgreens Boots Alliance Inc |
UK |
2020-12-20 |
2021-12-01 |
283187, ICE-COVID, NCT04590365 |
Phase 3 Clinical |
Not yet recruiting |
1 |
11 Months |
480 |
Iain S Whitaker, PhD FRCS, Zita M Jessop, MBBChir PhD |
2020-10-22 |
| FLAVOCOV Distributed Clinical Trial- COVID-19 |
Coronavirus disease 19 infection |
flavonoids alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
|
Kenya Medical Research Institute |
Kenya |
2020-11-01 |
2021-01-31 |
PACTR202010537777617 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
200 |
Leah Kigondu, Rick Sheridan, Willie Nyambati |
2020-10-21 |
| COREADOM: French Cohort of COVID-19 Patients With Post-intensive Care Syndrome |
Coronavirus disease 19 infection |
|
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assistance Publique Hopitaux de Paris |
|
France |
2020-10-15 |
2021-09-15 |
APHP200812, COREADOM, NCT04590170 |
Phase Not Applicable |
Not yet recruiting |
1 |
11 Months |
50 |
Camille : Camille, MD, Camille Camille, MD, Marie Benhammani-Godard, Marie-Martine Marie-Martine, MD, PhD |
2020-10-21 |
| VISION-Acute: The VISION-Acute Study |
Coronavirus disease 19 infection, Hypertension, Hypotension, Hypoxia, Respiratory disease |
Lifelight data collect app (Xim Ltd) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Xim Ltd |
Portsmouth Hospitals |
UK |
2020-10-31 |
2021-01-31 |
NCT04589923, PHT/2020/50, VISION-Acute |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
200 |
Laura Wiffen |
2020-10-20 |
| Allocetra-OTS in COVID-19, Phase II |
Coronavirus disease 19 infection, Multiple organ failure, Respiratory disease, Respiratory failure, Septic shock |
standard of care therapy alone, Allocetra plus Ringer's lactate solution |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hadassah Medical Organization |
Barzilai medical center, Tel Aviv Sourasky Medical Center |
Israel |
2020-05-07 |
2021-03-31 |
DM004, NCT04590053 |
Phase 2 Clinical |
Recruiting |
3 |
10 Months |
24 |
Dror Mevorach, MD, Peter V van Heerden, MD, Ronen Ben-Ami, Prof., Shlomo L Maayan, Prof. |
2020-10-26 |
| Levamizole in treatment of COVID-19 |
Coronavirus disease 19 infection |
levamisole alone, standard therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Isfahan University of medical Sciences |
|
Iran |
2020-10-22 |
|
IR.MUI.MED.REC.1399.246, IRCT20181208041886N1 |
Phase 2 Clinical |
Recruiting |
1 |
|
60 |
Dr. Shaghayegh Haghjoo, Morteza Pourahmad |
2020-10-22 |
| COVID-19 biomarker: Identification of biomarkers for prognosis of morbidity and mortality of SARS-CoV-2 (COVID-19) patients |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Munster |
|
Germany |
2020-04-09 |
|
AZ 2020-210-f-S, COVID-19 biomarker, DRKS00023322 |
Phase Not Applicable |
Recruiting |
1 |
|
100 |
Phil-Robin Tepasse |
2020-10-21 |
| A Clinical Trial of a Plasmid DNA Vaccine for COVID-19 (Covigenix VAX-001) in Adults |
Coronavirus disease 19 infection |
SARS-CoV-2 DNA vaccine (COVID-19), Entos/ Epivax alone |
COVID19 Spike glycoprotein modulator |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Entos Pharmaceuticals Inc |
Canadian Institutes of Health Research |
Canada |
2020-11-30 |
2021-06-30 |
ENTVAX01-101, NCT04591184 |
Phase 1 Clinical |
Not yet recruiting |
1 |
7 Months |
72 |
Gregory Reid, M.Sc, MBA, Sally Jones, Scott A. Halperin, M.D. |
2020-10-21 |
| Anhydrous Enol-Oxaloacetate (AEO) on Improving Fatigue in Post-COVID-19 Survivors |
Coronavirus disease 19 infection, Fatigue |
anhydrous enol-oxaloacetate (Terra Biological LLC) alone |
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Terra Biological LLC |
|
US |
2020-10-15 |
2021-06-15 |
NCT04592354, TB-AEO-2020 POST COVID FATIGUE |
Phase Not Applicable |
Recruiting |
1 |
8 Months |
40 |
Alan B Cash, MS, Lisa Tully, Ph.D. |
2020-10-21 |
| A prospective study to evaluate the accuracy of the Cue COVID-19 Test in patients |
Coronavirus disease 19 infection |
Cue COVID-19 Test alone |
|
|
Mayo Clinic Foundation |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
|
|
2020-10-20 |
| A phase I/II clinical study to assess MRT-5500 in the treatment of subjects with SARS-CoV-2 infection |
Coronavirus disease 19 infection |
SARS-CoV-2 mRNA vaccine (COVID-19), Sanofi Pasteur/ Translate Bio alone |
|
|
Sanofi SA |
|
|
2020-12-31 |
|
|
Phase 1/Phase 2 Clinical |
Planned |
0 |
|
|
|
2020-10-20 |
| A clinical trial to evaluate the efficacy of erdosteine in the treatment of hospitalized patients with COVID-19 infection with severe respiratory failure |
Coronavirus disease 19 infection, Respiratory failure |
erdosteine alone |
Elastase inhibitor |
|
Recipharm AB |
|
Italy |
|
|
|
Phase 2 Clinical |
Status not specified |
1 |
|
20 |
|
2020-10-20 |
| AERATOR: Studying aerosol emission of the COVID-19 virus in healthcare settings |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
North Bristol NHS Trust |
National Institute for Health Research (NIHR), United Kingdom Research & Innovation |
UK |
2020-09-19 |
2021-09-19 |
3.4, IRAS 288784, CPMS 47097, AERATOR, ISRCTN21447815 |
Phase Not Applicable |
Recruiting |
2 |
12 Months |
600 |
Dr Fergus Hamilton |
2020-10-22 |
| Experience In Managing Special Groups Of Person Under Surveillance In Kelantan |
Coronavirus disease 19 infection |
|
|
|
Ministry of Health, Malaysia |
|
Malaysia |
2020-10-18 |
2021-10-05 |
56079, NMRR-20-2238-56079 |
Phase Not Applicable |
Status not specified |
1 |
11 Months |
|
Dr Farah Munirah Binti Mior Mazlan, dr NIK AIDA BT NIK ADIB |
2020-10-20 |
| Treatment of Covid-19 Using Infrared and/or Vitamin C |
Coronavirus disease 19 infection |
Infrared sauna therapy alone, vitamin C alone |
|
Healthy volunteers accepted |
GAAD Medical Research Institute Inc |
|
Canada |
2020-10-30 |
2021-07-10 |
GAADMRI, NCT04584437 |
Phase Not Applicable |
Not yet recruiting |
1 |
8 Months |
400 |
Dr. Kwasi D Donyina, PhD, Yaa A Donyina, MDE |
2020-10-20 |
| A multicenter, clinical trial to validate the effectiveness of the Monocyte Distribution Width (MDW) hematology biomarker in the rapid detection of Multisystem Inflammatory Syndrome in Children (MIS-C) following SARS-CoV-2 infection |
Coronavirus disease 19 infection, Inflammatory disease |
|
|
|
Beckman Coulter Diagnostics |
Biomedical Advanced Research and Development Authority (BARDA), Johns Hopkins University School of Medicine, Massachusetts General Hospital, University of Florida |
US |
|
|
|
Phase Not Applicable |
Planned |
3 |
|
|
Lael Yonker, M.D |
2020-10-20 |
| Secondary attack rate of COVID-19 and risk factors for transmission |
Coronavirus disease 19 infection |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sri Ramachandra Institute of Higher Education and Research |
|
India |
2020-10-16 |
|
CTRI/2020/10/028439 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Manisha Arthur |
2020-10-20 |
| Efficacy of daclatasvir + sofosbuvir in patients with severe acute respiratory syndrome coronavirus (SARS-COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
daclatasvir/sofosbuvir (Danesh Pharmaceutical Development Company) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ahvaz University of Medical Sciences |
Ahvaz Jundishapur University of Medical Sciences |
Iran |
2020-06-25 |
|
IR.AJUMS.REC.1399.300, IRCT20200816048422N1 |
Phase 1/Phase 2 Clinical |
No longer recruiting |
1 |
|
70 |
Dr Fatemeh Ahmadi, Dr. Fatemeh Ahmadi, Dr. Mohammad Badawi, Dr. Zahra Fakhraei |
2020-10-20 |
| PRECISION: An observational PRECISION study , to examine the immune responses to COVID-19 in healthy volunteers who have recovered from COVID-19 or were asymptomatic |
Coronavirus disease 19 infection |
|
|
|
Columbia University, Tonix Pharmaceuticals Holding Corp |
|
US |
|
|
PRECISION, TNX-C002 |
Phase Not Applicable |
Recruiting |
1 |
|
|
Dr. Ilya Trakht, Dr. Sergei Rudchenko, Ph.D |
2020-10-19 |
| Effect of Ayurvedic Treatment Regimen in COVID-19 Patients |
Coronavirus disease 19 infection |
Variable regimens including Bilwadi Yog , Kantakaryavaleha , Shadangodak |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ministry of Ayush |
|
India |
2020-11-02 |
|
CTRI/2020/10/028437 |
Phase 3 Clinical |
Not yet recruiting |
3 |
|
380 |
Dr Leena Badgujar, Dr Milind B Nikumbh, Dr Shoeb Shaikh |
2020-10-21 |
| A trial to evaluate FX-06 in severe cases of COVID-19 |
Coronavirus disease 19 infection |
FX-06 alone |
Cadherin-5 modulator, Factor Ia modulator |
|
F4 Pharma GmbH |
|
Europe |
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-10-19 |
| Perspective of cancer patient in COVID-19 pandemic |
Cancer, Coronavirus disease 19 infection |
chemotherapy alone, radiotherapy alone, systemic therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Indira Gandhi Medical College |
|
India |
2020-12-01 |
|
CTRI/2020/10/028438 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
1000 |
Shabnum Thakur |
2020-10-21 |
| A trial to evaluate stem cell therapy as a treatment for acute symptoms of COVID-19 |
Coronavirus disease 19 infection |
stem cell therapy alone |
|
|
BioXcellerator |
|
US |
|
|
|
Phase Not Applicable |
Not yet recruiting |
1 |
|
|
|
2020-10-19 |
| This study is designed to look at certain blood parameters like biomarkers for predicting the outcome of COVID patients |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
St Johns Medical College |
|
India |
2020-10-25 |
|
CTRI/2020/10/028436 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
130 |
Dr Amarja Havaldar |
2020-10-20 |
| A phase III trial to evaluate post-exposure prophylaxis and pre-emptive treatment of AZD-7442 in covid-19 patients |
Coronavirus disease 19 infection |
AZD-7442 alone |
COVID19 Spike glycoprotein inhibitor |
|
AstraZeneca plc |
Biomedical Advanced Research and Development Authority (BARDA) |
US |
|
|
|
Phase 3 Clinical |
Planned |
1 |
|
1100 |
|
2020-10-23 |
| A phase III trial to evaluate the safety and efficacy of AZD7442 to prevention of COVID-19 |
Coronavirus disease 19 infection |
AZD-7442 alone |
COVID19 Spike glycoprotein inhibitor |
|
AstraZeneca plc |
Biomedical Advanced Research and Development Authority (BARDA) |
US |
|
|
|
Phase 3 Clinical |
Planned |
1 |
|
5000 |
|
2020-10-23 |
| Mental health of COVID 19 patients during outbreak |
Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression |
RTPCR test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
All India Institute of Ayurveda |
|
India |
2020-10-16 |
|
CTRI/2020/10/028432 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
400 |
Dr Shivakumar Harti |
2020-10-20 |
| CoMMinS: COVID-19 testing and infection control in schools |
Coronavirus disease 19 infection |
RNA PCR test alone, Saliva-based antibody test alone, Viral RNA genome sequencing alone |
|
|
University of Bristol |
Medical Research Council |
UK |
2020-09-01 |
2021-08-31 |
CoMMinS, IRAS 290071, ISRCTN82901740 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
5000 |
Prof Caroline Relton |
2020-10-20 |
| A phase III clinical trial of Sputnik V for the potential prevention of COVID-19 infection |
Coronavirus disease 19 infection |
Sputnik V alone |
COVID19 Spike glycoprotein modulator |
|
Gamalei Institute of Epidemiology and Microbiology |
|
Philippines |
|
|
|
Phase 3 Clinical |
Recruiting |
1 |
|
|
|
2020-10-19 |
| A phase III clinical trial of Sputnik V for the potential prevention of COVID-19 infection |
Coronavirus disease 19 infection |
Sputnik V alone |
COVID19 Spike glycoprotein modulator |
|
Gamalei Institute of Epidemiology and Microbiology |
|
United Arab Emirates, Saudi Arabia |
2020-10-13 |
|
|
Phase 3 Clinical |
Recruiting |
2 |
|
|
|
2020-10-19 |
| A clinical trial of ASLAN-003 for the treatment of Covid-19 and other viral infections |
Coronavirus disease 19 infection, Viral infection |
ASLAN-003 alone |
Dihydroorotate dehydrogenase inhibitor, p53 tumor suppressor protein stimulator |
|
ASLAN Pharmaceuticals Pte Ltd |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-10-26 |
| Cohort survey of healthcare workers with COVID-19 infection |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted |
Chiba University Graduate School of Medicine |
|
Japan |
2020-05-19 |
2020-06-11 |
UMIN000042142 |
Phase Not Applicable |
Completed |
1 |
|
103 |
Taka-aki Nakada, Takeo Kurita |
2020-10-21 |
| An observational, case report to determine the diagnosis and management of upper gastrointestinal bleeding caused by SARS-CoV-2 infection during hospitalization |
Coronavirus disease 19 infection, Gastrointestinal bleeding |
Yunnan white drugs alone, gastroscopy alone, Variable regimens including aluminum phosphate , esomeprazole , octreotide acetate , thrombin |
Factor IIa agonist, H+ K+ ATPase inhibitor, Somatostatin receptor agonist |
|
Sun Yat-Sen University |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
1 |
|
2020-10-21 |
| Evaluation of Respiratory profile and radiological changes in patients after recovery from COVID-19 |
Coronavirus disease 19 infection |
nintedanib alone, pirfenidone alone |
CSF-1 antagonist, FGF receptor antagonist, FGF1 receptor antagonist, FGF2 receptor antagonist, FGF3 receptor antagonist, Flt3 tyrosine kinase inhibitor, Lck tyrosine kinase inhibitor, Lyn tyrosine kinase inhibitor, PDGF receptor alpha antagonist, PDGF receptor antagonist, PDGF receptor beta antagonist, Src tyrosine kinase inhibitor, TGF beta receptor antagonist, VEGF receptor antagonist, VEGF-1 receptor antagonist, VEGF-2 receptor antagonist, VEGF-3 receptor antagonist, p38 MAP kinase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
All India Institute of Medical Sciences |
|
India |
2020-10-22 |
|
CTRI/2020/10/028372 |
Phase 4 Clinical |
Not yet recruiting |
1 |
|
500 |
Anant Mohan |
2020-10-20 |
| Experiences among nurses caring patients with COVID-19 |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Manipal Academy of Higher Education |
|
India |
2020-10-30 |
|
CTRI/2020/10/028373 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
30 |
Dr Leena Sequira, SHALINI G NAYAK |
2020-10-20 |
| A Clinical Study to Evaluate the Safety and Efficacy of CoviTone in Mild to Moderate COVID patients |
Coronavirus disease 19 infection |
CoviTone alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
|
|
India |
2020-10-22 |
|
CTRI/2020/10/028376 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
80 |
Dr M E Mohan, Jestin V Thomas |
2020-10-20 |
| KluT: COVID-19 Cluster in Temerloh: Is it related to tabligh? |
Coronavirus disease 19 infection |
|
|
|
|
|
|
2020-10-13 |
2021-02-08 |
55897, KluT, NMRR-20-2208-55897 |
Phase Not Applicable |
Recruiting |
0 |
3 Months |
|
Dr. Safaridah binti Anuar |
2020-10-20 |
| PVAS COVID-19: COVID-19: Public Awareness, Perception and Impact on Pharmacy Value Added Services (PVAS) in Kedah, Malaysia |
Coronavirus disease 19 infection |
|
|
|
|
|
Malaysia |
2020-10-15 |
2021-06-30 |
55892, NMRR-20-2195-55892, PVAS COVID-19 |
Phase Not Applicable |
Not yet recruiting |
1 |
8 Months |
|
Mrs Nurliana Binti Abdul Latif, norazila bt abdul ghani |
2020-10-19 |
| Effect of remdesivir in COVID-19 |
Coronavirus disease 19 infection |
remdesivir alone |
COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ahvaz University of Medical Sciences |
|
Iran |
2020-09-27 |
|
IR.AJUMS.REC.1399.407, IRCT20200404046937N5 |
Phase 2/Phase 3 Clinical |
Recruiting |
2 |
|
50 |
Dr Fatemeh Ahmadi, Mehdi Ahmadi Moghadam, Mehran Varnaseri, Mehran Varnasseri, Roohangiz Nashibi |
2020-10-19 |
| Cope-Corona: Identifying and strengthening personal resources to cope with the corona pandemic |
Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression, Psychiatric disorder |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tongji Hospital |
|
China |
2020-08-01 |
2023-07-31 |
ChiCTR2000038929, Cope-Corona |
Phase Not Applicable |
Not yet recruiting |
1 |
36 Months |
600 |
Heng Wu, Zheng Lu |
2020-10-19 |
| COVADIS study: COVID-19 Epidemic in West Africa (WA): infection dynamics and diagnostic approaches |
Coronavirus disease 19 infection |
COVID test kit alone |
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Medical Research Council Unit, The Gambia |
European and Developing Countries Clinical Trials Partnership |
Gambia |
2020-10-12 |
|
COVADIS study, PACTR202010472402152 |
Phase Not Applicable |
No longer recruiting |
1 |
|
1100 |
Annette Erhart, Bakary Conteh, Vivat Thomas Njie |
2020-10-19 |
| ANTICOV IMMUNO: The impact of COVID-19 treatment on the type, strength and duration of antibody and cellular immune responses in SARS-CoV-2 patients in sub-Saharan Africa Ancillary Study of the ANTICOV Study: An open-label, multicentre, randomised, adaptive platform trial of the safety and efficacy of several therapies, including antiviral therapies, versus control in mild / moderate cases of COVID-19 |
Coronavirus disease 19 infection |
hydroxychloroquine alone, lopinavir + ritonavir alone |
HIV protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Bernhard-Nocht-Institute for Tropical Medicine, Drugs for Neglected Diseases Initiative, Ifakara Health Institute, Institute of Tropical Medicine |
|
Egypt |
2020-09-21 |
|
ANTICOV IMMUNO, PACTR202010781639956 |
Phase Not Applicable |
Recruiting |
1 |
|
1000 |
Gemma Moncunill, James Arkinstall, Nathalie StrubWourgaft |
2020-10-20 |
| A clinical trial to evaluate the efficacy of polyvalent highdosage intravenous immunoglobulin to stabilize or improve the health of COVID-19 patients |
Coronavirus disease 19 infection |
polyvalent high-dosage intravenous immunoglobulin alone |
|
|
Grifols SA |
|
Spain |
|
|
|
Phase Not Applicable |
Planned |
1 |
|
|
|
2020-10-19 |
| KoCo19-CED-1: Clinical care situation, health problems and psychosocial burdens during the COVID-19-pandemic in patients with chronic inflammatory bowel disease (IBD) - Part 1: Baseline survey and seroprevalence of SARS-CoV-2 antibodies compared to Munich population cohort (KoCo19) |
Coronavirus disease 19 infection, Inflammatory bowel disease |
blood test alone |
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Klinikum der Universitat Muenchen |
|
Germany |
2020-07-04 |
|
20-523, DRKS00021698, DRKS00022155, KoCo19-CED-1 |
Phase Not Applicable |
Recruiting |
2 |
|
400 |
Elisabeth Klucker, Leandra Koletzko, Sibylle Koletzko, Simone Breiteneicher, Tobias Schwerd |
2020-10-20 |
| PRASACT: Clinical study to evaluate the effect of Ayurveda intervention as a prophylaxis for COVID-19 in Healthcare workers |
Coronavirus disease 19 infection |
Variable regimens including Amritotaram Kashayam Prakshepa , Chywanaprasha , Dasamoola Katutrayam Kashayam , Dhanvantaram Gutika , GuduchyAdi Kashayam Prakshepa , Haridrakhandam , Indukantam Kashayam , Nayopayam KS Prakshepa , Sudarshana Ghana Vati , Vasaristam+Kanakasavam , VidAryAdi KS |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ministry of Ayush |
|
India |
2020-10-30 |
|
CTRI/2020/10/028424, PRASACT |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
200 |
Dr Zankhana Buch |
2020-10-19 |
| A clinical study to see the effects and safety of PNB-001 in patients with moderate COVID-19 infection |
Coronavirus disease 19 infection |
PNB-001 alone, Standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Byramjee Jeejeebhoy Govt Medical College and Sassoon General Hospitals |
|
India |
2020-10-28 |
|
BCR-PNB-001, CT/ND/95/2020, CTRI/2020/10/028423 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
40 |
Dr Neeta Nargundkar, Dr Pradnya Bhalerao |
2020-10-20 |
| Effect of COVID-19 on lymphocyte and eosinophil count |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
All India Institute of Medical Sciences Patna |
|
India |
2020-10-24 |
|
CTRI/2020/10/028422 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
150 |
DR AMARJEET KUMAR |
2020-10-21 |
| The effect of synbiotic on inflammatory markers and clinical manifestations in patients with COVID-19 |
Coronavirus disease 19 infection |
Lactocar synbiotic alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Isfahan University of medical Sciences |
|
Iran |
2020-10-22 |
|
IR.MUI.MED.REC.1399.204, IRCT20200923048815N1 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
|
80 |
Majid Aghadavood Marnani, Masha Khodadoostan Shahraki, Shaghayegh Haghjoy Javanmard |
2020-10-22 |
| SaNPS: Stress and neuropsychiatric symptoms/disorders (ie, functional brain diseases): COVID-19 as a source of stress |
Acute stress disorder, Coronavirus disease 19 infection |
group wellbeing therapy group wellbeing therapy alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Xuanwu Hospital Of Capital Medical University |
|
China |
2020-01-04 |
2021-01-04 |
ChiCTR2000039079, SaNPS |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
400 |
Hongxing Wang |
2020-10-20 |
| PAP SURVEY: A Survey of Psychological Distress and Its Associated Factors Among Health Service Providers Amidst the Covid-19 Pandemic in Malaysia |
Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression |
|
|
Healthy volunteers accepted |
Selayang Hospital |
|
Malaysia |
2020-11-10 |
2020-12-16 |
56529, NMRR-20-2235-56529, PAP SURVEY |
Phase Not Applicable |
Status not specified |
1 |
1 Month |
|
Dr Muhammad Haniff Bin Abdullah |
2020-10-21 |
| Persuasion in Medicine: Experimental Evidence on Sender and Signal Effects |
Coronavirus disease 19 infection |
Video about safety and effectiveness alone, direct messaging on COVID-19 vaccine safety and efficacy alone |
|
Healthy volunteers accepted, Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Harvard University |
Massachusetts Institute of Technology, Stanford University |
US |
2019-12-20 |
2021-02-15 |
IRB19-1424, NCT04160975 |
Phase Not Applicable |
Recruiting |
1 |
13 Months |
3350 |
|
2020-10-19 |
| Kap of New Normal among HCW's in Hospital Kuala Lumpur and Hospital Sungai Buloh Regarding Covid-19 |
Coronavirus disease 19 infection |
|
|
|
University of Malaya |
|
Malaysia |
2020-11-01 |
2021-10-31 |
NMRR-20-2224-56820 |
Phase Not Applicable |
Status not specified |
2 |
12 Months |
|
Dr Sri Viknarajan A/L Puvendran |
2020-10-16 |
| COVID19-MSK INJECTION |
Coronavirus disease 19 infection, Rheumatoid arthritis |
|
|
|
HOSPITAL QUEEN ELIZABETH II |
|
Malaysia |
2020-10-31 |
2021-08-02 |
NMRR-20-2221-56202 |
Phase Not Applicable |
Status not specified |
1 |
9 Months |
|
MOHAMAD AZWAN BIN AZIZ |
2020-10-20 |
| EDWH COVID-19 |
Coronavirus disease 19 infection |
|
|
|
Melaka Hospital |
|
Malaysia |
2020-10-25 |
2020-12-31 |
NMRR-16-2910-29170 |
Phase Not Applicable |
Status not specified |
5 |
2 Months |
|
Madam NOORHALIZA BT ALI |
2020-10-20 |
| A study to assess safety and efficacy of natural killer cells in the treatment of covid-19 |
Coronavirus disease 19 infection |
K-NK-ID101 alone |
|
|
Abigail Wexner Research Institute, Kiadis Pharma BV |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-10-16 |
| The COVID PROFILE study |
Coronavirus disease 19 infection |
|
|
|
Walter and Eliza Hall Institute of Medical Research |
Royal Melbourne Hospital, The Peter Doherty Institute for Infection and Immunity, University of Melbourne |
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
300 |
Dr Vanessa Bryant, Professor Ivo Mueller |
2020-10-16 |
| NCoV-Radi: NCoV-Radi |
Coronavirus disease 19 infection |
chest radiography alone, computed tomography imaging alone |
|
|
The University of Hong Kong |
|
Hong Kong |
2020-02-10 |
2021-01-31 |
HKUCTR-2850, NCoV-Radi, UW 20-115, v1 |
Phase Not Applicable |
Recruiting |
1 |
11 Months |
50 |
Dr. Ming-Yen Ng, HKUCTR Administrator |
2020-10-19 |
| ICARD: The impact of COVID-19 pandemic-related activity restriction on the outcomes of chronic obstructive lung disease |
Chronic obstructive pulmonary disease, Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Nagoya University |
Nagoya University Graduate School of Medicine |
Japan |
2020-09-01 |
2023-03-31 |
ICARD, UMIN000042106 |
Phase Not Applicable |
Recruiting |
1 |
31 Months |
150 |
Akira Ando, Naozumi Hashimoto |
2020-10-20 |
| A Phase I, Open-Label, Parallel-Group, Single-Dose Study to Evaluate the Pharmacokinetics of Remdesivir and Metabolites in Participants with Normal Renal Function and Renal Impairment |
Coronavirus disease 19 infection |
remdesivir alone |
COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Gilead Sciences Inc |
|
Australia, Puerto Rico, US, Germany, New Zealand |
2020-11-02 |
|
ACTRN12620001048976p |
Phase 1 Clinical |
Not yet recruiting |
5 |
|
80 |
Dr Christian Schwabe |
2020-10-19 |
| REMOTE CONTROL: Home-based blood pressure monitoring of Hypertensive Diseases in Pregnancy - A randomized, controlled trial |
Coronavirus disease 19 infection, Hypertension, Pre-eclampsia |
Home-based blood pressure monitoring -app alone, automated BP machine alone, education and training alone |
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Campbelltown Hospital, Liverpool Hospital |
Heart Research Institute Ltd |
Australia |
2021-01-01 |
|
ACTRN12620001049965p, REMOTE CONTROL |
Phase Not Applicable |
Not yet recruiting |
1 |
|
300 |
Dr Theepika Rajkumar |
2020-10-21 |
| Extended SIR model |
Coronavirus disease 19 infection |
|
|
|
Clinical Research Centre |
|
|
2020-10-14 |
2021-10-13 |
56878, NMRR-20-2217-56878, model01 |
Phase Not Applicable |
Status not specified |
0 |
12 Months |
|
Pharmacist Law Kian Boon |
2020-10-19 |
| SERVQUAL Model in Hospital |
Coronavirus disease 19 infection |
health management alone |
|
|
Universiti Kebangsaan Malaysia |
|
Malaysia |
2020-11-01 |
2021-03-31 |
54898, NMRR-20-2131-54898 |
Phase Not Applicable |
Not yet recruiting |
34 |
5 Months |
|
Siti Nurfadhilah binti Arsad |
2020-10-19 |
| Clinical study of an Ayurveda formulation containing Gold and Indian Gooseberry along with Tulasi juice as an add on therapy in standard care of COVID 19 patients |
Coronavirus disease 19 infection |
Swarna Amalaki alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Ministry of Ayush |
Acharya Vinoba Bhave Rural Hospital |
India |
2020-11-02 |
|
CTRI/2020/10/028414 |
Phase 2 Clinical |
Not yet recruiting |
0 |
|
60 |
Anjalee Chiwane, Jyothy K B |
2020-10-20 |
| Psychological responses of medical staff during COVID-19 and the adjustment effect of brief mindfulness meditation |
Coronavirus disease 19 infection |
brief mindfulness meditation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Naval Medical Research Institute of PLA |
National Natural Science Foundation of China |
China |
2021-01-01 |
2021-12-31 |
ChiCTR2000039002 |
Phase 0 Clinical |
Not yet recruiting |
1 |
12 Months |
400 |
Liu Yunzi |
2020-10-19 |
| School teachers experience in online teaching during this COVID-19 situation |
Acute stress disorder, Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Manipal Academy of Higher Education |
|
India |
2020-10-13 |
|
CTRI/2020/10/028412 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
200 |
JOSHUA RAYMOND ANDRADE, UMESH THONSE |
2020-10-21 |
| A Phase III clinical trial for inactivated novel coronavirus pneumonia (COVID-19) vaccine (Vero cells) |
Coronavirus disease 19 infection, Viral pneumonia |
COVID-19 vaccine (inactivated, Vero cells/intramuscular), Wuhan Institute of Biological Products/Wuhan Institute of Virology, CAS alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
China National Biotec Group, Wuhan Institute of Biological Products Co Ltd |
|
Morocco |
2020-09-02 |
2020-12-31 |
ChiCTR2000039000 |
Phase 3 Clinical |
Recruiting |
1 |
3 Months |
600 |
Professeur Abouqal Redouane, Wei Chen |
2020-10-23 |
| A population based survey on COVID-19 infection in Goa state among both urban and rural population |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Government of Goa |
|
India |
2020-10-16 |
|
CTRI/2020/10/028384 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1000 |
Dr Dhananjay Lad, Dr Vijaykumar Patil |
2020-10-20 |
| Clinical characteristics and laboratory parameters of COVID-19 patients on oxygen |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
National Cancer Institute, Jhajjar, AIIMS |
|
India |
2020-10-20 |
|
CTRI/2020/10/028340 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Dr Anuja Pandit |
2020-10-20 |
| To study the relationship between spirituality,hope, distress and ability to bounce back from stress among family members of recovered COVID-19 patients |
Acute stress disorder, Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Government Medical College and Hospital,Chandigarh |
|
India |
2020-11-01 |
|
CTRI/2020/10/028339 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
30 |
Anushka Negi, Dr Ajeet Sidana, Dr Manoj Kumar |
2020-10-19 |
| The Provider Insurance Revenue Study in Healthcare Providers in the United States of America |
Coronavirus disease 19 infection |
|
|
|
|
University of California Irvine |
US |
2020-10-01 |
2021-10-15 |
NCT04587245, PIRSTUDY |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
100 |
Charles Bronson, Charles Bronson, MBA, Henry Broeska, Henry Broeska, PhD, Sheridan Merrick, BA |
2020-10-21 |
| NEUROCOV-19: Investigation of COVID-19 associated neurological comorbidities |
Coronavirus disease 19 infection, Neurological disease |
electrophysiological examination alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universitatsklinikum Essen |
|
Germany |
2020-10-25 |
|
20-9284-BO, DRKS00023312, NEUROCOV-19 |
Phase Not Applicable |
Recruiting |
1 |
|
250 |
Mark Stettner, Michael Fleischer |
2020-10-21 |
| Dyhor-19: Diagnosis of Endocrine Dysfunctions in COVID-19 |
Coronavirus disease 19 infection, Endocrine disease |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital, Montpellier |
|
France |
2020-03-01 |
2020-05-30 |
Dyhor-19, NCT04587375, RECHMPL20_0205 |
Phase Not Applicable |
Completed |
1 |
2 Months |
50 |
Philippe GUILPAIN, MD, PhD |
2020-10-16 |
| PROSPER: Pregnancy Outcomes During the Pandemic: Using Placental Pathology and Gene Expression to Understand Fetal Risk |
Coronavirus disease 19 infection |
|
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Prisma Health-Upstate |
|
US |
2020-08-04 |
2021-09-30 |
NCT04585945, PRO00101090, PROSPER |
Phase Not Applicable |
Recruiting |
3 |
13 Months |
100 |
Jessica Britt, PhD, Jessica L Britt, PhD |
2020-10-16 |
| Development and Use of a Post-COVID-19 Quality of Life Patient-reported Outcome Measure |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
|
|
UK |
2020-10-07 |
2025-10-31 |
MED-ASST 33, NCT04586413 |
Phase 1/Phase 2 Clinical |
Recruiting |
1 |
60 Months |
100 |
Ravi Jandhyala, Rose Watson |
2020-10-16 |
| An observational study to determine the postdischarge venous thromboembolism rates following hospital admission with COVID-19 |
Coronavirus disease 19 infection, Thromboembolism |
venous thromboembolism analysis alone |
|
|
Kings College Hospital NHS Trust |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
|
|
2020-10-18 |
| MySteps-CoV: eHealth Intervention on Physical Activity for Type 2 Diabetics - Frustrated by COVID-19 |
Coronavirus disease 19 infection, Non-insulin dependent diabetes |
ExSed app alone, Usual care alone, counselling contacts alone, eHealth alone, hip-worn accelerometer alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
UKK-instituutti |
North Karelia Central Hospital, University Of Eastern Finland |
Finland |
2019-03-06 |
2020-10-31 |
MYSTEPS ETL 303/2017, MySteps-CoV, NCT04587414 |
Phase Not Applicable |
No longer recruiting |
1 |
19 Months |
122 |
Harri Sievanen, Tommi Vasankari, MD, PhD |
2020-10-20 |
| Improving the Mental Health of Resident Physicians and Fellows Through Transcendental Meditation |
Acute stress disorder, Coronavirus disease 19 infection |
Transcendental meditation alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Arizona |
|
US |
2020-11-30 |
2021-12-31 |
2008969193, NCT04586309 |
Phase Not Applicable |
Not yet recruiting |
1 |
13 Months |
50 |
Alison Sutton-Ryan, LCSW, Rachel E M Cramton, MD |
2020-10-19 |
| Endothelial dysfunction in severe COVID-19 disease |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
All India Institute Of Medical Sciences, Rishikesh |
|
India |
2020-10-19 |
|
CTRI/2020/10/028361 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
40 |
Rohit Walia |
2020-10-21 |
| Psychiatric sequelae in COVID-19 infection recovered resident doctors and interns of a tertiary health care hospital |
Coronavirus disease 19 infection, Psychiatric disorder |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Seth GS Medical College |
|
India |
2020-10-19 |
|
CTRI/2020/10/028360 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
60 |
Dr Neena S Sawant |
2020-10-16 |
| MoxiCov: Feasibility and Impact of Remote Oximetry in Patients Hospitalized With COVID-19 |
Coronavirus disease 19 infection, Hypoxia |
Digital oximeter alone, cardiac frequency monitoring alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo |
|
Brazil |
2020-06-22 |
2021-06-22 |
5058/20/087, MoxiCov, NCT04587921 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
90 |
Daniel Queiróz, PhD, Diego Prieto, Msc, Geraldo Lorenzi Filho, Geraldo Lorenzi, M.D. PhD, Luciano Drager, M.D. PhD, Pedro Genta, M.D PhD |
2020-10-16 |
| A clinical trial to evaluate the effectiveness and safety of Vedicinals-9- a Herbal formulation in mild to moderate COVID-19 patients |
Coronavirus disease 19 infection |
Vedicinals-9 alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
|
|
India |
2020-10-19 |
|
CTRI/2020/10/028364, EPRD0202-010920 |
Phase 2 Clinical |
Not yet recruiting |
2 |
|
124 |
Dr Govinda Narke, Dr Nitin Shinde, Yogendra Kumar Choudhary |
2020-10-16 |
| The barriers encountered by health-service providers while giving healthcare to patients admitted to COVID hospitals of Odisha |
Coronavirus disease 19 infection |
online self-administered questionnaire alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Kalinga Institute of Medical Sciences |
|
India |
2020-11-01 |
|
CTRI/2020/10/028363 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1000 |
Nipa Singh |
2020-10-16 |
| The Study of 'Gam-COVID-Vac' Vaccine Against COVID-19 With the Participation of Volunteers of >/= 60 years old |
Coronavirus disease 19 infection |
Sputnik V alone |
COVID19 Spike glycoprotein modulator |
Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Gamalei Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation Collaborator |
|
Russian Federation |
2020-10-15 |
2020-12-20 |
05-GAM-COVID-VAC-2020, NCT04587219 |
Phase 2 Clinical |
Not yet recruiting |
1 |
2 Months |
110 |
Inna Dolzhikova, PhD, Nikita Lomakin, MD, PhD |
2020-10-21 |
| Study to assess the efficacy of deep breathing Pranayama technique in addition to conventional allopathic treatment in management of COVID-19 |
Coronavirus disease 19 infection |
deep breathing Pranayama alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
|
|
India |
2020-10-15 |
|
CTRI/2020/10/028362, JRH/IEC/2020/COVID19/Pranayama breathing technique |
Phase Not Applicable |
Not yet recruiting |
1 |
|
278 |
Dr Anuja Santosh Kulkarni |
2020-10-19 |
| Improving Cancer Screening and Prevention During the COVID-19 Pandemic in Underserved Populations of Rhode Island |
Breast tumor, Colorectal tumor, Coronavirus disease 19 infection |
Cancer screening alone, Colonoscopy alone, Informational videos and social media campaign alone, Mammogram alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Rhode Island Hospital |
|
US |
2020-08-28 |
2022-09-01 |
1613494-3, NCT04587258 |
Phase Not Applicable |
Recruiting |
1 |
24 Months |
100 |
Cristina Pacheco, MD, Don Dizon, MD, Howard Safran, MD |
2020-10-17 |
| Study to Assess the Effect of Meplazumab on COVID-19 |
Coronavirus disease 19 infection |
meplazumab alone, standard of care alone |
Basigin inhibitor, COVID19 Spike glycoprotein inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Pacific Meinuoke Biopharmaceutical |
|
|
2020-10-30 |
2021-04-30 |
MPZ-II-02, NCT04586153 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
0 |
6 Months |
456 |
Shuangshuang Liu, Xiaochun Chen |
2020-10-16 |
| ETHICOVID: Operation of the GHPSJ Clinical Ethical Reflection Assistance Group During the COVID-19 Period |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Groupe Hospitalier Paris Saint-Joseph |
|
France |
2020-11-09 |
2022-04-30 |
ETHICOVID, ETHICOVID, NCT04586140 |
Phase Not Applicable |
Not yet recruiting |
1 |
17 Months |
30 |
Helene BEAUSSIER, PharmD, pHD, Marie-Lorraine de WARREN, Nurse |
2020-10-16 |
| CoCovSDRA: Effect of Corticosteroid Treatment on Prognosis in ARDS Secondary to Covid-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
corticosteroid treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Central Hospital, Nancy, France |
|
France |
2020-03-01 |
2020-12-31 |
2020PI109, CoCovSDRA, DUBOST_2020_PI_109, NCT04586114 |
Phase Not Applicable |
No longer recruiting |
1 |
10 Months |
200 |
Sebastien GIBOT |
2020-10-20 |
| A trial to evaluate ALF-1001 for the preventing the spread of COVID-19 |
Coronavirus disease 19 infection |
ALF-1001 alone |
IL-22 antagonist, IL-23 antagonist, Interferon alpha 14 ligand, Interleukin 17A ligand inhibitor, Interleukin 17F ligand inhibitor, TNF alpha ligand inhibitor |
|
ILC Therapeutics Ltd |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-10-15 |
| A phase III clinical trial to evaluate the efficacy of SARS-CoV-2 peptide vaccine (li-Key, COVID-19), Generex for the potential prevention of COVID-19 infection |
Coronavirus disease 19 infection |
SARS-CoV-2 peptide vaccine (li-Key, COVID-19), Generex alone |
|
|
Generex Biotechnology Corp |
Bintai Kinden Corp |
US |
|
|
|
Phase 3 Clinical |
Planned |
1 |
|
|
|
2020-10-15 |
| A case-control study of lenzilumab in patients with severe and critical COVID-19 |
Coronavirus disease 19 infection |
lenzilumab alone |
GM-CSF ligand inhibitor, Immunoglobulin G1 modulator, Immunoglobulin kappa modulator |
|
Humanigen Inc |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
39 |
|
2020-10-15 |
| A patient case report to evaluate lenzilumab in severe and critical COVID-19 patient |
Coronavirus disease 19 infection |
lenzilumab alone |
GM-CSF ligand inhibitor, Immunoglobulin G1 modulator, Immunoglobulin kappa modulator |
Male, European Ancestry |
Humanigen Inc |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
|
|
2020-10-15 |
| VEGF and sFlt-1 Levels in the Pathogenesis and Severity of COVID-19 Disease |
Cardiac failure, Cardiovascular disease, Coronavirus disease 19 infection, Multiple organ failure, Renal failure, Respiratory failure |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Alabama at Birmingham |
|
US |
2020-05-22 |
2023-05-20 |
IRB-300005378, NCT04587323 |
Phase Not Applicable |
Recruiting |
1 |
35 Months |
100 |
Dylan Addis, MD, Shanna H Graves |
2020-10-16 |
| A clinical trial of TLC-19 for the treatment of COVID-19 |
Coronavirus disease 19 infection |
TLC-19 alone |
|
Healthy volunteers accepted |
Taiwan Liposome Co |
|
Taiwan, Australia |
|
|
|
Phase 1 Clinical |
Recruiting |
2 |
|
30 |
|
2020-10-24 |
| MOR: Mouth Rinses for Inactivation of COVID-19 |
Coronavirus disease 19 infection |
Betadine gargle alone, Colgate Optic White alone, Colgate Total mouthwash alone, Listerine alone, Peridex alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
University of North Carolina |
|
US |
2020-10-31 |
2023-09-30 |
20-2040, MOR, NCT04584684 |
Phase 2 Clinical |
Not yet recruiting |
1 |
35 Months |
480 |
Laura Jacox, DMD, PhD, S.T. Phillips, Wendy Lamm |
2020-10-16 |
| Outcomes of and Prognosis Factors for COVID-19 Patients - An Observational Study |
Coronavirus disease 19 infection |
|
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Xiangya Hospital Of Central South University |
|
China |
2020-01-17 |
2021-02-28 |
ChiCTR2000038943 |
Phase Not Applicable |
Recruiting |
1 |
13 Months |
233 |
Suixin Liu, Yaoshan Dun |
2020-10-16 |
| Gynecological Laparoscopic Surgery during COVID-19 Pandemic |
Coronavirus disease 19 infection, Gynecological disorder |
|
|
|
Putrajaya Hospital |
|
Malaysia |
2020-09-30 |
2020-10-30 |
NMRR-20-2129-56450 |
Phase Not Applicable |
Status not specified |
1 |
1 Month |
|
Dr Raimi Zamriah Hasan, Dr Tunisha a/p Ganisakran |
2020-10-16 |
| Biochemistry and hematology sample handling during COVID-19: Hospital Sungai Uloh experience |
Coronavirus disease 19 infection |
|
|
|
Hospital Sungai Buloh |
|
Malaysia |
2021-01-25 |
2021-01-27 |
56713, NMRR-20-2127-56713 |
Phase Not Applicable |
Status not specified |
1 |
|
|
Dr NUR AMALINA BINTI YUSOFF, Dr Sharifah Khairul Atikah |
2020-10-19 |
| A large, pragmatic, open-label study to assess efficacy and safety of bamlanivimab monotherapy or combination therapy with etesevimab |
Coronavirus disease 19 infection |
bamlanivimab alone, bamlanivimab plus etesevimab |
COVID19 Spike glycoprotein modulator |
|
Eli Lilly & Co |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-10-15 |
| ACTIV-3: A clinical trial of bamlanivimab for the treatment of patients with ambulatory and hospitalized COVID-19 patients |
Coronavirus disease 19 infection |
bamlanivimab plus remdesivir |
COVID19 Spike glycoprotein modulator, COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator |
|
Eli Lilly & Co, National Institutes of Health |
|
|
|
|
ACTIV-3 |
Phase Not Applicable |
Suspended |
0 |
|
1000 |
|
2020-10-20 |
| BLAZE-4: A clinical trial to evaluate IV doses of etesevimab in combination with bamlanivimab |
Coronavirus disease 19 infection |
bamlanivimab plus etesevimab |
COVID19 Spike glycoprotein inhibitor, COVID19 Spike glycoprotein modulator |
|
Eli Lilly & Co |
|
|
|
|
BLAZE-4 |
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-10-15 |
| An observational study on the clinical characteristics of metastatic prostate cancer patients infected with COVID-19 in South Italy |
Coronavirus disease 19 infection, Hormone refractory prostate cancer, Metastatic prostate cancer |
LHRH agonist therapy alone, chemotherapy alone, enzalutamide alone, hormonal treatment alone |
Androgen receptor antagonist, Cytochrome P450 3A4 stimulator, DNA binding protein inhibitor, Prostate specific antigen modulator, Translocation associated protein inhibitor |
Male |
University of Molise |
|
Italy |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
2 |
|
2020-10-15 |
| A Phase II Study of RTB-101 as COVID-19 Post-Exposure Prophylaxis in Older Adults |
Coronavirus disease 19 infection |
dactolisib alone |
Phosphoinositide 3-kinase inhibitor, mTOR complex 1 inhibitor, mTOR complex 2 inhibitor |
Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
resTORbio Inc |
Harvard Medical School, National Institute on Aging, University of Connecticut Health Center |
US |
2020-10-31 |
2021-02-28 |
3R01AG064802-02S1, NCT04584710, RTB101-211 |
Phase 2a Clinical |
Recruiting |
2 |
4 Months |
60 |
Lisa Kenyon-Pesce, Medical Monitor, Peggy Gagnon |
2020-10-20 |
| D-dimer Adjusted Versus Therapeutic Dose Low-molecular-weight Heparin in Patients With COVID-19 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
D-dimer and weight adjusted therapy alone, enoxaparin sodium alone |
Low molecular weight heparin |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ain Shams University |
|
Egypt |
2020-08-01 |
2020-12-31 |
FMASU P35/ 2020, NCT04584580 |
Phase 4 Clinical |
Recruiting |
1 |
5 Months |
50 |
Ashraf Madkour, Fatma Soliman E Ebeid |
2020-10-16 |
| OD-doxy-PNVCOV Old Drug 'DOXY' for Prevention of New Virus Virus OD-doxy-PNV |
Coronavirus disease 19 infection |
doxycycline plus zinc |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Hopital Militaire Principal d'instruction de Tunis |
Dacima Consulting |
Tunisia |
2020-10-30 |
2021-03-01 |
NCT04584567, UR17DN05 |
Phase 3 Clinical |
Not yet recruiting |
1 |
4 Months |
1100 |
Batikh R Riadh, physican, Ben Moussa M mohamed, physican, Ferjani M Mustapha, physican, Gharsallah H Hedi, physican, Mrabet A Ali, physican, Stambouli N nejla, phd, Youssfi MA Mohamed Al, physican |
2020-10-15 |
| The Effect of Aerobic Exercise on Immune Biomarkers and Symptoms Severity and Progression in Patients With COVID-19: A Pilot, Randomized, Control Trial |
Coronavirus disease 19 infection, Gastrointestinal disease, Upper respiratory tract infection, Viral pneumonia |
Moderate Intensity Aerobic Exercises alone, aerobic exercise alone, hydroxyclorocin sulphate (Plaquenil) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
|
|
Turkey |
2020-01-01 |
2020-10-01 |
AEROBIC EXERCISE, COVID-19, NCT04581291 |
Phase Not Applicable |
Completed |
1 |
9 Months |
30 |
Motaz Alawna |
2020-10-15 |
| LIFTCOVID: Lift Mobile Mindfulness for COVID-19 Distress Symptoms |
Coronavirus disease 19 infection, Depression, Generalized anxiety disorder, Respiratory distress syndrome |
Lift mobile mindfulness program app alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Duke University |
National Center for Complementary and Integrative Health |
US |
2020-11-01 |
2021-09-30 |
3U01AT009974-03S1, LIFTCOVID, NCT04581200, PRO00106306 |
Phase Not Applicable |
Not yet recruiting |
4 |
11 Months |
300 |
Allie Frear, Catherine L Hough, MD, MSc, Christopher Cox, MD, Christopher E Cox, MD, Jeffrey McKeehan, Lee Kamphuis, MPH, Madeleine McDougal, Marc Moss, MD, Theodore Iwashyna, MD, PhD |
2020-10-16 |
| SYNBIOTIC COV STUDY: An Evaluation of a Synbiotic Formula for Patients With COVID-19 Infection |
Coronavirus disease 19 infection |
health supplements (Synbiotic) alone, standard care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Chinese University of Hong Kong |
|
Hong Kong |
2020-08-13 |
2022-04-30 |
NCT04581018, SYNBIOTIC COV STUDY, SYNBIOTIC COV STUDY |
Phase Not Applicable |
Recruiting |
1 |
20 Months |
50 |
Amy Li, Kitty Cheung, Siew Chien Ng, Siew Chien Ng, PhD |
2020-10-16 |
| Clinical trail of remdesivir in Covid-19 patinets |
Coronavirus disease 19 infection, Viral pneumonia |
remdesivir alone |
COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator |
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
|
|
Hungary |
2020-10-12 |
|
2020-004928-42, REM-ENY-01 |
Phase 3 Clinical |
Recruiting |
1 |
|
2000 |
CRO |
2020-10-16 |
| DYADS: Dysphagia and Dysphonia Outcomes in SARS CoV-2 (COVID-19) Infection |
Coronavirus disease 19 infection, Dysphagia, Dysphonia |
fiberoptic endoscopic evaluation of swallowing test alone, videofluoroscopy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cambridge University Hospitals NHS Foundation Trust |
|
UK |
2020-09-15 |
2021-12-31 |
20/NW/0333, DYADS, NCT04584658 |
Phase Not Applicable |
Recruiting |
1 |
15 Months |
36 |
Andrie Schembri, BSc, Brian Fish, FRCS (ORL-HNS), Claudia Russell, MSc, Ekpemi Irune, Ekpemi Irune, FRCS (ORL-HNS), Liam Masterson, FRCS (ORL-HNS), Rachel Kyd, Sarah Pilsworth, MSc |
2020-10-20 |
| Patterns of Arrhythmias and Conduction Block in COVID-19 Patients and Its Relation to Myocardial Injury Detected by Cardiac Magnetic Resonance |
Atrioventricular block, Coronavirus disease 19 infection, Heart arrhythmia, Heart injury |
SSFP sequence based cine imaging alone, cardiac magnetic resonance imaging alone, gadolinium alone, myocardial perfusion imaging alone, tissue characterization imaging alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assiut University |
|
Egypt |
2020-11-01 |
2024-01-01 |
ARRHYTHMIAS IN COVID-19, NCT04584411 |
Phase Not Applicable |
Not yet recruiting |
1 |
38 Months |
50 |
Ahmed AR Hassaan, bachelor, Alaa A El-Moniem, Doctorate, Doaa A Fouad, Doctorate, Maram M Shafiq, student, Mohamed A.H Abdelhafez, Doctorate, Shimaa S Khider, Doctorate |
2020-10-15 |
| Ain Shams University Experience: Clinical Determinants of Hospitalized COVID-19 Patients |
Coronavirus disease 19 infection |
laboratory test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ain Shams University |
|
Egypt |
2020-06-27 |
2020-12-30 |
FMASU P30/ 2020, NCT04584606 |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
100 |
Ashraf Elmaraghy, Fatma Soliman E Ebeid |
2020-10-16 |
| COPP2-study: Clinical features of COVID-19 in pediatric patients, long-term effects |
Coronavirus disease 19 infection |
|
|
|
Amsterdam UMC |
|
Netherlands |
2020-10-01 |
2022-03-01 |
COPP2-study, NL8926 |
Phase Not Applicable |
Not yet recruiting |
1 |
17 Months |
120 |
Caroline Kosterink-Brackel |
2020-10-15 |
| LIVECOVIDFREE: Lung Structure-Function In Survivors of Mild and Severe COVID-19 Infection |
Coronavirus disease 19 infection |
6 min walk test alone, biological sampling alone, computed tomography alone, forced oscillation technique alone, hyperpolarized xenon-129 alone, magnetic resonance imaging alone, plethysmography alone, spirometry alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Western Ontario |
London Health Sciences Centre Research Inc |
Canada |
2020-12-01 |
2024-12-01 |
LIVECOVIDFREE, NCT04584671, ROB0050 |
Phase Not Applicable |
Not yet recruiting |
1 |
48 Months |
200 |
Angela Wilson, RRT, Grace E Parraga, PhD |
2020-10-15 |
| ReCOVer: Cognitive Behavioral Therapy for post-COVID-19 fatigue |
Coronavirus disease 19 infection, Fatigue |
internet-based cognitive behavioral therapy (iCBT) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Amsterdam UMC |
The Netherlands Organisation for Health Research and Development |
Netherlands |
2020-10-05 |
2022-10-05 |
NL8947, ReCOVer |
Phase Not Applicable |
Recruiting |
1 |
24 Months |
114 |
Tanja Kuut |
2020-10-16 |
| COVSPERM: Pilot Study to Detect SARS-CoV-2 Virus in Sperm |
Coronavirus disease 19 infection |
blood sampling alone, nasopharyngeal sampling alone, saliva sampling alone, semen sampling alone, urine sampling alone |
|
Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Centre Hospitalier Universitaire de Toulouse |
|
France |
2020-10-31 |
2022-02-28 |
2020-A01610-39, COVSPERM, NCT04584593, RC31/20/0202 |
Phase Not Applicable |
Not yet recruiting |
1 |
16 Months |
50 |
Louis BUJAN, PR, Louis BUJAN, Pr |
2020-10-16 |
| Investigation of Validity and Reliability of Post-COVID-19 Functional Status Scale |
Coronavirus disease 19 infection |
Data collection alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hacettepe University |
|
Turkey |
2020-09-02 |
2021-12-02 |
GO 20/788, NCT04584450 |
Phase Not Applicable |
Recruiting |
1 |
15 Months |
100 |
Aslihan Cakmak, Aslıhan Çakmak, Deniz Inal-Ince, Ebru Calik Kutukcu, Ebru Çalık-Kütükcü, Esra Kınacı, Gülay Sain-Güven, Lale Özışık, Melda Saglam, Naciye Vardar-Yagli, Nursel Çalık-Başaran, Oğuz Abdullah Uyaroğlu |
2020-10-15 |
| COVIRIC: Sars-Cov-2 Viral Infection (COVID-19) in Patients With Chronic Inflammatory Rheumatism |
Coronavirus disease 19 infection, Rheumatoid arthritis, Spondylarthritis |
immune response assessment alone, immunosuppressive therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assistance Publique Hopitaux de Paris |
|
France |
2020-06-11 |
2023-12-31 |
APHP200598, COVIRIC, NCT04584541 |
Phase Not Applicable |
Recruiting |
1 |
42 Months |
150 |
Adèle bellino, Corinne Miceli-Richard, MD, PhD |
2020-10-17 |
| Study to Evaluate the Safety, Pharmacokinetics and Efficacy of STI-2020 (COVI-AMG) in Outpatients With COVID-19 |
Coronavirus disease 19 infection |
COVI-AMG alone, standard of care alone |
COVID19 Spike glycoprotein inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sorrento Therapeutics Inc |
|
|
2020-12-31 |
2021-04-30 |
AMG-COV-101, NCT04584697 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
0 |
4 Months |
50 |
Mike Royal, MD |
2020-10-16 |
| Prognostic Factors and Outcomes of COVID-19 Cases in Ethiopia |
Coronavirus disease 19 infection |
|
|
|
Ethiopian Public Health Institute |
Dutch Ministry of Health, Welfare and Sport |
Ethiopia |
2020-10-30 |
2021-11-14 |
EPHI NATIONAL COHORT, NCT04584424 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
6390 |
Masresha Tessema, Masresha Tessema, PhD, Saro Abdella, MPhil, Saro Abdella, mPhil |
2020-10-15 |
| An observational, clinical series study to evaluate the effect of sarilumab in patients with COVID‐19 pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
Variable regimens including azithromycin , cobicistat , darunavir , enoxaparin sodium , hydroxychloroquine , sarilumab |
Cytochrome P450 3 inhibitor, IL-6 receptor antagonist, Low molecular weight heparin |
|
San Giovanni di Dio Hospital |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
8 |
|
2020-10-14 |
| An observational and single-center study of hydroxychloroquine treatment in COVID-19 in Wuhan, China |
Coronavirus disease 19 infection |
hydroxychloroquine alone |
|
|
Tongji Hospital |
|
China |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
30 |
|
2020-10-14 |
| Telerehabilitation for elderly people with Alzheimer's disease and their caregivers |
Alzheimers disease, Coronavirus disease 19 infection |
Telerehabilitation alone, cognitive and multicomponent motor exercises alone, psychoeducation alone |
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fundação Universidade Federal De São Carlos |
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior |
Brazil |
2020-09-20 |
2021-06-25 |
4.255.764, RBR-825p57, U1111-1252-3238, _89476318.0.0000.5504 |
Phase Not Applicable |
Recruiting |
1 |
9 Months |
48 |
Carla A. Andreatto, Carolina Tsen, Larissa Pires de Andrade |
2020-10-19 |
| A phase II clinical trial MVA-SARS-2-S vaccine for the potential prevention of COVID-19 infection |
Coronavirus disease 19 infection |
MVA-SARS-2-S alone |
COVID19 Spike glycoprotein modulator |
|
Universitätsklinikum Hamburg-Eppendorf |
|
Germany |
2020-12-31 |
|
|
Phase 2 Clinical |
Planned |
4 |
|
|
|
2020-10-14 |
| Prolonged Prone Positioning for COVID-induced Acute Respiratory Distress Syndrome (ARDS): A Pilot Study |
Coronavirus disease 19 infection, Respiratory distress syndrome |
Prolonged Proned Positioning alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Alabama at Birmingham |
|
US |
2021-01-31 |
2021-06-30 |
IRB-300005979, NCT04581811 |
Phase Not Applicable |
Not yet recruiting |
1 |
5 Months |
52 |
David B Page, M.D., David Page, Derek Russell, M.D., Mark Dransfield, M.D. |
2020-10-15 |
| coVIHd-19: Impact of the Epidemic of COVID-19 Infection Among People Living With HIV (SARS-CoV-2) |
Coronavirus disease 19 infection, HIV infection |
questionnaire alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier de Tourcoing |
|
France |
2020-10-31 |
2021-12-31 |
NCT04581746, RIPH_2020_7, coVIHd-19 |
Phase Not Applicable |
Not yet recruiting |
3 |
14 Months |
1800 |
Emmanuelle AISSI, MD, Jean Luc SCHMIT, PU-PH, Pauline THILL, MD, Solange TREHOUX, PhD |
2020-10-15 |
| Group CBT For Perinatal Anxiety |
Coronavirus disease 19 infection |
Group Cognitive Behaviour Therapy for Perinatal Anxiety (CBT-PA) alone |
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Manitoba |
|
Canada |
2020-10-31 |
2021-09-30 |
H2020:095, NCT04581681 |
Phase Not Applicable |
Not yet recruiting |
1 |
11 Months |
50 |
Gillian Alcolado |
2020-10-18 |
| A phase Ib/IIa clinical study to assess VIR-7832 in the treatment of patients with SARS-CoV-2 infection |
Coronavirus disease 19 infection |
VIR-7832 alone |
COVID19 Spike glycoprotein modulator |
|
GlaxoSmithKline plc, Vir Biotechnology Inc |
|
|
2020-12-31 |
|
|
Phase 1/Phase 2 Clinical |
Planned |
0 |
|
|
|
2020-10-14 |
| CAMELOT: Camostat Efficacy versus Placebo for Outpatient Treatment of COVID-19 |
Coronavirus disease 19 infection |
camostat mesylate alone |
Serine protease inhibitor, Transmembrane serine protease 2 inhibitor, Trypsin inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sagent Pharmaceuticals Inc |
|
US |
2020-10-31 |
2021-01-31 |
CAMELOT, NCT04583592, NI03-CV19-001 |
Phase 2 Clinical |
Not yet recruiting |
12 |
3 Months |
300 |
Atasi Jana, M.D., Brett Foster, Cheryl Hargrove, Erin Kelly, Jackie Duckett, Janet Nuttall, M.P.H., Janett Jalil, Julie Lafave, Niurka Romero, Olia Nayor, Priscilla Hernandez, Rabia Gilani, Yelamis Cartaya, Yeslin Arias |
2020-10-15 |
| Mental Imagery to Increase Face Covering Use in UK-based Public Places During the COVID-19 Pandemic |
Coronavirus disease 19 infection |
Mental imagery alone, Process imagery alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of East London |
University of Manchester |
UK |
2020-08-19 |
2020-12-01 |
ETH2021-0006, NCT04583449 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
250 |
Dominic Conroy, PhD |
2020-10-15 |
| ImmuneSense COVID-19 Study |
Coronavirus disease 19 infection |
T-Detect SARS-CoV-2 assay alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Adaptive Biotechnologies Corp |
Covance Inc |
US |
2020-10-09 |
2021-01-09 |
NCT04583982, PRO-00781 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
125 |
Jennifer Dines, MD, Jia Qadeer, Sarah Duffy, Thomas Manley, MD |
2020-10-14 |
| Validation of a Rapid, Non-invasive Point-of-care IVD Test for Diagnosis of SARS-COV-2 (COVID-19) Infection (EasyCov) |
Coronavirus disease 19 infection |
EasyCov IVD test alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Firalis SAS |
Istanbul University |
Turkey |
2020-10-31 |
2021-03-31 |
NCT04583319, ST0194 |
Phase Not Applicable |
Recruiting |
1 |
5 Months |
160 |
Arif Atahan, Prof.MD, Rodwell Mkhwananzi, MD, Selçuk Şen, Stéphanie Boutillier, PhD |
2020-10-22 |
| TeleCCCAP: Feasibility and Quality of TeleConsultation in Pediatric Anesthesia |
Anesthesia, Coronavirus disease 19 infection |
teleconsultation alone |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Centre Hospitalier Universitaire de Toulouse |
|
France |
2020-10-07 |
2022-03-14 |
2020-A02275-34, NCT04583865, RC31/20/0220, TeleCCCAP |
Phase Not Applicable |
No longer recruiting |
1 |
17 Months |
400 |
KERN Delphine, MD |
2020-10-13 |
| Negative predictive value of the FebriDx host response point-of-care test in patients presenting to a single Australian Emergency Department with suspected COVID-19 |
Coronavirus disease 19 infection |
FebriDx finger prick test alone |
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Planet Innovation |
|
Australia |
2020-11-01 |
2022-05-31 |
ACTRN12620001029987p, ANZCTR379997 |
Phase Not Applicable |
Not yet recruiting |
1 |
19 Months |
300 |
Paul Buntine, Shelley Westgarth-Nugent |
2020-10-15 |
| BET-B; ACTIV-5/BET study: ACTIV-5/Big Effect Trial (BET-B) for the Treatment of COVID-19 |
Coronavirus disease 19 infection |
lenzilumab plus remdesivir |
COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, GM-CSF ligand inhibitor, Immunoglobulin G1 modulator, Immunoglobulin kappa modulator, RNA polymerase modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Humanigen Inc, National Institute of Allergy and Infectious Diseases |
National Institutes of Health |
US |
2020-10-19 |
2021-07-01 |
20-0013B, BET-B, ACTIV-5/BET study, NCT04583969 |
Phase 2 Clinical |
Recruiting |
6 |
8 Months |
200 |
20-0013 Central Contact |
2020-10-25 |
| Evaluation of the Performance of the Covid-19 Ag BSS Rapid Antigenic Test in Symptomatic Children in a Pediatric Emergency Department |
Coronavirus disease 19 infection |
Biosynex Covid-19 Ag-BSS test alone |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Centre Hospitalier Intercommunal Creteil |
|
France |
2020-10-01 |
2021-01-01 |
NCT04583189, SPEEDYCOVI |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
500 |
BISCARDI Sandra, MD, Camille JUNG, Ph D |
2020-10-21 |
| A clinical study to assess the efficacy and safety of Tinefcon in patients with moderate COVID-19 infection |
Coronavirus disease 19 infection |
Tinefcon alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Life Molecular Imaging |
|
India |
2020-10-12 |
|
CTRI/2020/10/028335, Tinefcon/01/20 |
Phase 3 Clinical |
Not yet recruiting |
4 |
|
60 |
Dr Alben Sigamani, Dr Mala Kaneria, Dr Mehul Shah, Dr Rahul Tambe, Mridul Sharma, Rajiv Salvi |
2020-10-15 |
| Prospective on evaluation of use of , “AyurCoro3” as an add on medication for the treatment purpose in COVID-19 patients |
Coronavirus disease 19 infection |
AyurCov3 alone, Standard of Care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
|
|
India |
2020-10-13 |
|
CTRI/2020/10/028333 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
500 |
Dr Nanasaheb Memane, Dr Vijaykumar Gawali |
2020-10-16 |
| BET-A; ACTIV-5/BET study: Big Effect Trial (BET-A) for the Treatment of COVID-19 |
Coronavirus disease 19 infection |
remdesivir plus risankizumab |
COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, IL-23 antagonist, RNA polymerase modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Institute of Allergy and Infectious Diseases |
National Institutes of Health |
US |
2020-10-14 |
2021-07-01 |
20-0013A, BET-A, ACTIV-5/BET study, NCT04583956 |
Phase 2 Clinical |
Recruiting |
10 |
8 Months |
200 |
20-0013 Central Contact |
2020-10-20 |
| DYSPO: Photoplethysmographic Scaling of Dyspnea |
Coronavirus disease 19 infection, Dyspnea, Respiratory failure |
ECG alone, Pulse oximeter alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Institutul de Urgenta pentru Boli Cardiovasculare Prof.Dr. C.C. Iliescu |
|
Romania |
2020-10-01 |
2021-07-30 |
18751, DYSPNOEA - SPO2 CURVE STUDY, DYSPO, NCT04582838 |
Phase Not Applicable |
Recruiting |
2 |
9 Months |
60 |
Balan Cosmin, Consultant, Balan Ion Cosmin, Cristian Cobilinschi, Consultant, Serban I Bubenek Turconi, Professor |
2020-10-14 |
| Differential Expression of Cytokines, Transcriptome and miRNA in Coronavirus Disease 2019 (COVID-19) Egyptian's Patients |
Coronavirus disease 19 infection |
C-reactive protein test alone, D-dimer test alone, PCR test alone, complete blood count test alone, cytokine profiling alone, differential leukocyte test alone, ferritin test alone, miRNA analysis alone, transcriptome analysis alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tanta University |
|
Egypt |
2020-10-04 |
2022-10-03 |
CTM_COVID-19, NCT04583566 |
Phase Not Applicable |
Recruiting |
2 |
24 Months |
40 |
Mohammed Eid, Doctor, Mohammed El Shanshoury, Professor, Mohammed Hanteera, Professor |
2020-10-14 |
| KNC19: Knust COVID-19 Clinical Trial |
Coronavirus disease 19 infection |
Nibima alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
kwame Nkrumah University of Science and Technology |
|
Ghana |
2020-12-01 |
2021-01-29 |
KNC19, PACTR202010690466874 |
Phase 2 Clinical |
Not yet recruiting |
1 |
1 Month |
20 |
Ellis Owusu Dabo, Mohamed Mutocheluh |
2020-10-14 |
| Send-In Sample Collection for Comprehensive Analyses of Innate and Adaptive Immune Responses During Acute COVID-19 and Convalescence |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Institute of Allergy and Infectious Diseases |
National Institutes of Health Clinical Center |
US |
2020-10-28 |
2025-08-31 |
000044-I, 10000044, NCT04582903 |
Phase Not Applicable |
Recruiting |
1 |
58 Months |
500 |
Helen C Su, M.D., Helen Su, M.D. Ph. D, Sandra M Maxwell, R.N. |
2020-10-24 |
| Comparison of the effectiveness of two treatment regimens in patients with COVID-19 |
Coronavirus disease 19 infection |
Sovodak (Faravan Rojan Mohaghegh Darou) plus hydroxychloroquine (Iran Daru) |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Iran University of Medical Sciences |
|
Iran |
2020-07-19 |
|
IR.IUMS.FMD.REC.1399.407, IRCT20200328046885N1 |
Phase 2 Clinical |
No longer recruiting |
2 |
|
300 |
Dr Abbas Motevalian, Mahin Jamshidi Makiani |
2020-10-15 |
| NICORISCOVID: Tobacco and Nicotine Consumption and the Risk of Acquisition of Coronavirus Disease 2019 (COVID-19) |
Coronavirus disease 19 infection |
RT-PCR alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assistance Publique Hopitaux de Paris |
|
France |
2020-10-12 |
2020-12-01 |
APHP200663, NCT04583761, NICORISCOVID |
Phase Not Applicable |
Not yet recruiting |
1 |
1 Month |
1000 |
Marina Karmochkine, MD |
2020-10-15 |
| Evaluate the Safety, Tolerability, Pharmacodynamics, Pharmacokinetics, and Immunogenicity of HLX-71 (Recombinant Human Angiotensin-converting Enzyme 2-Fc Fusion Protein for COVID-19) in Healthy Adult Subjects |
Coronavirus disease 19 infection |
HLX-71 alone |
Angiotensin converting enzyme 2 inhibitor |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Hengenix Biotech Inc |
|
US |
2020-11-30 |
2021-05-31 |
HLX71-001US-253460, NCT04583228 |
Phase 1 Clinical |
Not yet recruiting |
1 |
6 Months |
40 |
Esther Yoon, MD, Jinyun Bai |
2020-10-15 |
| Physical Activity Levels of Hypertensive and Healthy Individuals Under Social Isolation During the COVID-19 Pandemic |
Coronavirus disease 19 infection, Hypertension |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Hacettepe University |
|
Turkey |
2020-06-01 |
2021-02-01 |
GO 20/610, NCT04583345 |
Phase Not Applicable |
Recruiting |
1 |
8 Months |
32 |
Beyza Nur Karaduz, MSc, Ebru Calik Kutukcu, PhD, Naciye Vardar Yagli, PhD, S. Lale Tokgozoglu, Professor, Yusuf Ziya Sener, MD |
2020-10-20 |
| NICOVID-PREV: Efficacy of Nicotine in Preventing COVID-19 Infection in Caregivers |
Coronavirus disease 19 infection |
Nicotine patch (Nicopatchlib) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assistance Publique Hopitaux de Paris |
|
France |
2020-10-31 |
2021-10-31 |
2020-003722-23, APHP200538, NCT04583410, NICOVID-PREV |
Phase 3 Clinical |
Not yet recruiting |
2 |
12 Months |
1633 |
Florence TUBACH, MD, Guylaine LABRO, MD, Raphael GAILLARD, MD, Zahir AMOURA, MD |
2020-10-20 |
| AIDED: Acute Kidney Injury in Covid-19 |
Coronavirus disease 19 infection, Renal injury |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospitals Of Derby and Burton NHS Foundation Trust |
|
UK |
2020-11-30 |
2022-09-30 |
AIDED, NCT04583293, UHDB/2020/076 |
Phase Not Applicable |
Not yet recruiting |
1 |
22 Months |
220 |
Maarten W Taal, Professor, Nitin V Kolhe, Doctor |
2020-10-24 |
| DISCOVER: The Salivary Raman COVID-19 Fingerprint |
Coronavirus disease 19 infection |
Aramis Raman microscope (Horiba Jobin-Yvon) alone, Raman spectroscopy alone, portable Raman spectrometer alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fondazione Don Carlo Gnocchi - Onlus |
|
Italy |
2020-06-01 |
2021-06-01 |
DISCOVER, FDG_SALIVACOVID01, NCT04583306 |
Phase Not Applicable |
Recruiting |
2 |
12 Months |
120 |
Cristiano Carlomagno, PhD, Jorge Navarro, MD, Luca C Bianchi, MD, Marzia Bedoni, PhD, Paolo I Banfi, MD |
2020-10-14 |
| Evaluation of the efficacy and safety of Atazanavir/Ritonavir plus Hydroxychloroquine regimen in patients with moderate COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
atazanavir sulfate + ritonavir (HIV infection), Mylan Laboratories plus hydroxychloroquine |
HIV protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Mazandaran University of Medical Sciences |
|
Iran |
2020-08-22 |
|
IR.MAZUMS.REC.1399.602, IRCT20200328046886N2 |
Phase 3 Clinical |
Recruiting |
1 |
|
120 |
Hamideh Abbaspour Kasgari, Hamideh Abbaspour kasgari, Research and technology department |
2020-10-14 |
| A study to analyze results of COVID-19 testing in anesthesia procedures using the polymerase chain reaction (PCR) |
Coronavirus disease 19 infection |
polymerase chain reaction (PCR) test alone |
|
|
American Society of Anesthesiologists |
|
US |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
1033 |
|
2020-10-18 |
| A clinical study of Reveal 35C in the detection of pneumonia (including COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Reveal 35C alone |
|
|
KA Imaging Inc |
|
Canada |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
|
|
2020-10-13 |
| Association of calcium channel blocker use with COVID-19 clinical outcome: a metaanalysis |
Cardiovascular disease, Coronavirus disease 19 infection |
calcium channel blocker therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universitas Airlangga |
|
Asia |
2020-10-11 |
|
UMIN000042076 |
Phase Not Applicable |
Recruiting |
0 |
|
1000 |
Eka Mulia, Mochamad Yusuf |
2020-10-14 |
| Effectiveness of favipiravir in comparison with tenofovir alafenamid in patients with COVID-19 |
Coronavirus disease 19 infection |
favipiravir (Nafas farmed Co) alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ardabil University of Medical Sciences |
|
Iran |
2020-09-20 |
|
IR.ARUMS.REC.1399.310, IRCT20150808023559N23 |
Phase 2 Clinical |
Recruiting |
1 |
|
100 |
Dr Farhad Pourfarzi, Somaieh Matin |
2020-10-14 |
| A Global, Phase IIb/III Clinical Trial to Assess the Effect of CV-07050101 in Patients With Coronavirus Disease 19 Infection |
Coronavirus disease 19 infection |
SARS-CoV-2 mRNA vaccine (COVID-19), CureVac alone |
COVID19 Spike glycoprotein modulator |
|
CureVac AG |
|
|
2020-12-31 |
|
|
Phase 2/Phase 3 Clinical |
Planned |
0 |
|
30000 |
|
2020-10-13 |
| COVID-19 Watch + COVID-19 Pulse |
Coronavirus disease 19 infection |
COVID Watch alone, PCORI Pulse alone, automated text-messaging program alone, telemedicine nurse-led care alone, triage protocol alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Pennsylvania |
|
|
2020-10-21 |
2021-10-31 |
844043, NCT04581863 |
Phase Not Applicable |
Not yet recruiting |
0 |
12 Months |
850 |
Dina Abdel-Rahman, BS, Jessie Hemmons, MS |
2020-10-14 |
| Effect of Beta-interferon and methylprednisolone in COVID-19 |
Coronavirus disease 19 infection |
Variable regimens including Keltra , beta-interferon , hydroxychloroquine , methylprednisolone , naproxen |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shahid Sadoughi University of Medical Sciences and Health Services |
|
Iran |
2020-05-04 |
|
IR.SSU.REC.1399.040, IRCT20200825048514N1 |
Phase 3 Clinical |
No longer recruiting |
1 |
|
60 |
Fatemeh sadat Aghaei meybodi, Masoud Mirzaei |
2020-10-14 |
| A Phase I/II Study to Assess the Safety, Tolerability and Pharmacokinetics of NGM-621 in Healthy Subjects, and to Assess the Safety, PK and Efficacy in Subjects With Moderate to Severe ARDS Caused by COVID-19 |
Adult respiratory distress syndrome, Coronavirus disease 19 infection |
NGM-621 alone |
Complement C3 inhibitor |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
NGM Biopharmaceuticals Inc |
|
|
2020-10-31 |
2021-09-30 |
621-CP-102, NCT04582318 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
0 |
11 Months |
48 |
NGM Study Director |
2020-10-14 |
| Effect of Blood Transfusion in COVID-19 |
Coronavirus disease 19 infection |
packed cell alone, standard treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Boushehr University of Medical Sciences |
|
Iran |
2020-10-11 |
|
IR.BPUMS.REC.1399.108, IRCT20201003048904N1 |
Phase 2 Clinical |
Recruiting |
1 |
|
40 |
Farhad Abbasi, Farhad abbasi, Gholamreza khamisipour, Negar Changizi |
2020-10-13 |
| Proportional Open Ventilation (POV) Device and Its Efficacy in Managing Acute Respiratory Failure in COVID-19 Patients |
Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure |
Life2000 Ventilator alone, high-flow nasal cannula therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hill-Rom Holdings Inc |
|
US |
2020-08-28 |
2020-10-31 |
CR-RR-2020-004, NCT04581161 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
10 |
Jonathan Shelver, MD, Malia Remackel, Marissa Peterson |
2020-10-13 |
| Comparison of tocilizumab versus itolizumab in covid-19 patient |
Coronavirus disease 19 infection |
tocilizumab alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
All India Institute of Medical Sciences Patna |
|
India |
2020-10-19 |
|
CTRI/2020/10/028325 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
50 |
Dr Poonam kumari |
2020-10-20 |
| Study to Investigate Long-term Pulmonary and Extrapulmonary Effects of COVID-19 |
Coronavirus disease 19 infection, Lung disease |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Inselspital, Berne |
|
Switzerland |
2020-05-01 |
2023-06-01 |
2020-00799, NCT04581135 |
Phase Not Applicable |
Recruiting |
9 |
37 Months |
500 |
Christian Clarenbach, PD, Christian Garzoni, PD, Christophe von Garnier, Prof., Kurt De Jaegere, Manuela Funke-Chambour, MD, Manuela Funke-Chambour, PD, Marco Mancinetti, MD, Martin Brutsche, Prof., Paola Gasche Soccal, Prof., Pierre-Olivier Bridevaux, Prof., Sebastian R. Ott, PD |
2020-10-13 |
| COVID-IYON: Study Examining Data Pertaining to Clinical Outcomes and Organizational Responses to the 2020 SARS-CoV-2 Pandemic |
Cancer, Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cancer Trials Ireland |
|
Ireland |
2020-04-29 |
2021-06-30 |
COVID-IYON, CTRIAL-IE 20-01, NCT04581070 |
Phase Not Applicable |
Recruiting |
11 |
14 Months |
300 |
Dr. Andrew Hodgson, Dr. Anne Fortune, Dr. Derville O'Shea, Dr. Ezzat ElHassadi, Dr. Gerard Crotty, Dr. Janusz Krawczyk, Dr. Larry Bacon, Dr. Liam Smyth, Dr. Paula Calvert, Dr. Ruth Clifford, Dr. Ruth Morrell, Dr. Silvie Blazkova, Dr. Sinéad Cuffe, Dr. Siobhan Glavey, Prof. Bryan Hennessy, Prof. Cathy Kelly, Prof. Helen Enright, Prof. Janice Walshe, Prof. Linda Coate, Prof. Roisin Connolly |
2020-10-14 |
| An Experiment to Evaluate the Safety of agenT-797 in COVID-19 Patients With Severe Difficulty Breathing |
Coronavirus disease 19 infection, Respiratory distress syndrome |
agenT-797 alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
AgenTus Therapeutics Inc |
Agenus Inc |
US |
2020-09-21 |
2021-10-15 |
C-1300-01, NCT04582201 |
Phase 1 Clinical |
Recruiting |
1 |
12 Months |
55 |
Agenus, Inc. Clinical Trial Information, Koen Van Besien, MD, Koen Van Besien, MD, PhD, Medical Director |
2020-10-13 |
| Assessment of memory cells response to Mycobacterium Indicus Pranii vaccination |
Coronavirus disease 19 infection, Mycobacterium infection |
Mycobacterium Indicus Pranii (MIP) Vaccine alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Manashi Chakrabarti Foundation |
|
India |
2020-10-20 |
|
CTRI/2020/10/028326, NKPROTOCOL0401 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
40 |
Dr Jyoti Rastogi, Dr Suparno Chakrabarti |
2020-10-20 |
| SARS-CoV2_KIDS: SARS-CoV2 Antibodies in Pediatric Patients (COVID-19) |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
University of Erlangen-Nurnberg Medical School |
|
Germany |
2020-10-05 |
2022-05-31 |
405_20 BC, NCT04581148, SARS-CoV2_KIDS |
Phase Not Applicable |
Not yet recruiting |
1 |
19 Months |
2000 |
Adrian Regensburger, MD, Antje Neubert, PhD |
2020-10-13 |
| AyurCoro3 Prophylaxis: Evaluation of use of , 'study medication' for prophylaxis in frontline health care workers involved in treating COVID-19 patients |
Coronavirus disease 19 infection |
AyurCoro-3 alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Bhaktivedanta Hospital and Research Institute |
|
India |
2020-10-09 |
|
AyurCoro3 Prophylaxis, CTRI/2020/10/028324 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
120 |
Dr Nanasaheb Memane, Dr Vijaykumar Gawali |
2020-10-15 |
| An Online-platform to Improve Patient-centered Care During the COVID-19 Pandemic: a GIMEMA Surveillance Program in Hematological Malignancies |
Coronavirus disease 19 infection, Hematological neoplasm |
IMEMA-ALLIANCE Platform online monitoring system alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Gruppo Italiano Malattie EMatologiche dell'Adulto |
|
|
2020-10-31 |
2024-10-31 |
GIMEMA-ALLIANCE PLATFORM, NCT04581187 |
Phase Not Applicable |
Not yet recruiting |
0 |
48 Months |
400 |
|
2020-10-13 |
| Impact of the COVID-19 pandemic on graduating dental interns: A student’s perspective |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs) |
Manipal College of Dental Sciences |
|
India |
2020-10-21 |
|
CTRI/2020/10/028296 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
400 |
Dr Mathangi Kumar |
2020-10-13 |
| COSMIC-19: Continuous Signs Monitoring In Covid-19 Patients |
Coronavirus disease 19 infection |
Isansys Patient Status Engine alone, continuous vital sign monitoring alone, machine learning artificial intelligence technology alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The Christie NHS Foundation Trust |
Aptus Clinical Ltd, Manchester University NHS Foundation Trust, Zenzium Ltd |
UK |
2020-07-11 |
2021-02-01 |
CFTSP187, COSMIC-19, NCT04581031 |
Phase Not Applicable |
Recruiting |
2 |
6 Months |
60 |
Anthony Wilson, Fiona Thistlethwaite, Fiona Thistlethwaite, MB BChir PhD |
2020-10-14 |
| Analysis of the SARS-CoV-2 specific immune response in persons with SARS-CoV-2 infection (COVID-19) |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted |
University of Homburg |
Bethanien Krankenhaus gGmbH, Universitat des Saarlandes |
Germany |
2020-10-15 |
|
76/20, DRKS00023086 |
Phase Not Applicable |
Not yet recruiting |
2 |
|
190 |
Martina Sester, Simon Herkenrath |
2020-10-13 |
| Clinical Trial For SARS-CoV-2 Vaccine (COVID-19) |
Coronavirus disease 19 infection |
CoronaVac alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Sinovac Biotech Ltd |
|
Turkey |
2020-09-14 |
2021-04-15 |
9026-ASI, NCT04582344 |
Phase 3 Clinical |
Recruiting |
24 |
7 Months |
13000 |
Ali Mert, Prof., Alpay Azap, Prof., Assoc. Prof., Aydın Yılmaz, Prof., Emin Halis Akalın, Prof., Fatma Şebnem Erdinç, Prof., Gülgün Dilek Arman, Prof., Gürdal Yılmaz, Prof., Hatice Rahmet Güner, Prof., Hüsnü Pullukçu, Prof., Murat Akova, Prof., Murat Akova, Professor, Mustafa Kemal Çelen, Prof., Sedat Altın, Prof., Serap Şimşek Yavuz, Prof., Serhat Ünal, Prof., Sıla Akhan, Prof., Taner Yıldırmak, Assoc. Prof., Taner Yıldırmak, Prof., Volkan Korten, Prof., Yaşar Bayındır, Prof., Yeşim Taşova, Prof., Ömer Fehmi Tabak, Prof., Özgür Batum, Specialist, İftihar Köksal, Prof., İlhami Çelik, Prof., İlkay Karaoğlan, Prof., Şükran Köse, Prof. |
2020-10-13 |
| Validation of Laboratory Techniques, Strategies, and Types of Samples for Epidemiological Control in the Covid-19 Pandemic |
Coronavirus disease 19 infection |
LAMP technique alone, Pool LAMP alone, Pool RT-PCR alone, RT-PCR alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
CUNY Hunter College |
Universidad Autonoma Juan Misael Saracho |
Bolivia |
2020-10-08 |
2020-11-30 |
NCT04581083, PROY - UAJMS001/2020 |
Phase Not Applicable |
Recruiting |
1 |
1 Month |
30 |
Carmen Amanda Delagadillo Delgadillo, MD, Jimena Martinez, MD, Jorge Tejerina, Lic., Kenji Shoji, PhD, Lucia Alvarado Arnez, PhD, Paloma Rojas Saunero, MD, MSc, Rodrigo Arce Cardozo, Rodrigo Arce Cardozo, MD, MPH, Rodrigo Arce Cardozo, MD,MPH, Roxana Valdez Zamorano, Wilson Muriel Argollo, MD |
2020-10-21 |
| PHRUCov01: Trial of Triazavirin (TZV) for the Treatment of Mild to moderate COVID-19 |
Coronavirus disease 19 infection |
standard of care treatment alone, triazavirin alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Wits Health Consortium (Pty) Ltd |
Perinatal HIV Research Unit, PharmaCentrix (Pty) Ltd, University of the Witswatersrand |
South Africa |
2020-09-08 |
2021-12-31 |
NCT04581915, PHRU COV01, PHRUCov01 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
15 Months |
420 |
Fatima Mayat, Firdaus Nabeemeeah, MBBCh, Neil A Martinson, MBChB, Tumelo Moloantoa, MBChB |
2020-10-20 |
| A phase III, global. non-contact trial to assess CoronaVac in healthcare workers in Dhaka, Bangladesh |
Coronavirus disease 19 infection |
CoronaVac alone |
|
|
LSK Global Pharma Services Co Ltd |
|
Bangladesh |
|
|
|
Phase 3 Clinical |
Planned |
1 |
|
4200 |
|
2020-10-12 |
| CLASSIC: Perceptions of the Clinical and Psychosocial Impact of Covid-19 in Patients With Neuromuscular and Neurological Disorders |
Coronavirus disease 19 infection, Duchenne dystrophy, Neurological disease, Neuromuscular disease, Spinal muscular atrophy |
|
|
Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Royal Brompton & Harefield NHS Trust |
|
UK |
2020-09-11 |
2020-12-17 |
286495, CLASSIC, NCT04581577 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
75 |
Anita K Simonds, MD MBBS, Anita Simonds, MBBS, Kinesh Patel, PhD, Lydia A Spurr, MBBS BMedSci, Lydia Spurr, MBBS, Martin R Cowie, MD MSc, Mary Morrell, PhD |
2020-10-13 |
| Oscillation and Lung Expansion Therapy in Patients With COVID-19 |
Coronavirus disease 19 infection |
MetaNeb System alone, oscillation and lung expansion (OLE) therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hill-Rom Holdings Inc |
Emory University, Northwestern University |
US |
2020-09-28 |
2021-01-01 |
CR-RR-2020-002, NCT04582214 |
Phase Not Applicable |
Recruiting |
2 |
3 Months |
30 |
Brian Becker, RT, Colin Swenson, MD, Elizabeth Cox, Lindsay Downing, MPH, Lisa Wolfe, MD, Phill Cooper |
2020-10-13 |
| Coro-Buddy: Buddy) Prevalence of Antibodies Against SARS-CoV-2 Virus That Causes COVID-19 in Tubingen Children |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Tubingen |
|
Germany |
2020-07-02 |
2021-12-31 |
CORO-BUDDY, Coro-Buddy, NCT04581889 |
Phase Not Applicable |
Recruiting |
1 |
17 Months |
2380 |
Andrea Kreidenweiss, Dr., Jana Held, Dr, Jana Held, Dr., Rolf Fendel, Dr., Yudi Tatiana Röckl-Pinilla, Dr. |
2020-10-15 |
| PK and Safety of Remdesivir for Treatment of COVID-19 in Pregnant and Non-Pregnant Women in the US |
Coronavirus disease 19 infection |
remdesivir alone |
COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator |
Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
International Maternal Pediatric Adolescent AIDS Clinical Trials Group |
|
US, Puerto Rico |
2020-10-15 |
2022-01-15 |
DAIDS STUDY ID 38746, IMPAACT 2032, NCT04582266 |
Phase Not Applicable |
Not yet recruiting |
17 |
15 Months |
40 |
Adriana Drada, FMD, CCRP, Aleisha Collinson-Streng, RN, BSN, Alice Stek, MD, Allison Agwu, MD, Barsha Chakraborty, BS, Brookie Best, PharmD, MAS, Christy Beneri, DO, Debra McLaud, RN, Diana Clarke, PharmD, Elizabeth Greene, MPH, Ellen Chadwick, MD, Ellen Cooper, MD, MPH, Gwendolyn Scott, MD, Irma L. Febo Rodriguez, M.D., Jaime Deville, MD, Katherine Knapp, MD, Kathleen George, MPH, LaTeshia Thomas-Seaton, Lourdes Topete, RN, Margaret Sanders, MPH, Mariam Aziz, MD, Mark Mirochnick, MD, Martina Badell, MD, Mary Paul, MD, Maureen McNichols, MSN, CCRP, Megan Loughran, Michele Carter, BS, RN, Mobeen Rathore, MD, Nina Sublette, PhD, APRN-BC, Ruth E. Santos, RN, MPH, BSN, Saniyyah Mahmoudi, ARNP, Shelley Buschur, RN, CNM, Stephen Spector, MD |
2020-10-13 |
| MEDyMAP: Mapping COVID-19 Spread in a Tertiary Hospital |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital General Universitario de Valencia |
University of Valencia |
Spain |
2020-10-02 |
2021-06-15 |
COVID19-MAPA, MEDyMAP, NCT04581096 |
Phase Not Applicable |
Recruiting |
1 |
8 Months |
3000 |
Adina Iftimi, PhD, Carolina Romero García, PhD, Carolina S Romero Garcia, PhD, Carolina Soledad Romero Garcia |
2020-10-13 |
| A phase II clinical trial of CYP-001 for the treatment of respiratory distress associated with COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
mesenchymoangioblast-derived mesenchymal stem cell therapy (Cymerus, critical limb ischemia/graft versus host disease/asthma/diabetic foot ulcer), Cynata/FUJIFILM alone |
|
|
Cynata Therapeutics Ltd |
|
|
|
|
|
Phase 2 Clinical |
Planned |
0 |
|
|
|
2020-10-12 |
| Patients Reactions Towards Their Diagnosis as Having COVID-19 |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
ClinAmygate |
|
Egypt |
2020-10-10 |
2020-11-15 |
NCT04581928, PR0020 |
Phase Not Applicable |
Not yet recruiting |
1 |
1 Month |
300 |
Emad R Issak, MD |
2020-10-13 |
| Impact of COVID-19 on Psoriasis Practice |
Coronavirus disease 19 infection, Psoriasis |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cairo University |
|
Egypt |
2020-09-17 |
2020-10-31 |
KAPU2020 10, NCT04581044 |
Phase Not Applicable |
Recruiting |
1 |
1 Month |
150 |
Asmaa Abdelnaby, MD, Mohamed HM EL-Komy, MD, Mona El-Kalioby, MD |
2020-10-13 |
| A pivotal, randomized, double-blind study to evaluate CPI-006 in hospitalized COVID-19 patients |
Coronavirus disease 19 infection |
CPI-006 alone |
CD73 antagonist |
|
Corvus Pharmaceuticals Inc |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-10-12 |
| A randomized, phase II clinical trial to assess safety and efficacy of KT-PC-301 in the treatment of subjects with COVID-19-related acute respiratory disease syndrome (ARDS) |
Coronavirus disease 19 infection, Respiratory disease |
KT-PC-301 alone |
|
|
Koligo Therapeutics Inc |
|
US |
|
|
|
Phase 2 Clinical |
Planned |
1 |
|
75 |
Mohamed Saad, MD |
2020-10-26 |
| Evaluation of the effectiveness of intravenous infusion of human COVID-19 hyperimmune plasma with specific antibody titer in hospitalized patients with Covid-19: a randomized clinical trial |
Coronavirus disease 19 infection, Viral pneumonia |
human COVID-19 hyperimmune plasma alone, human COVID-19 hyperimmune plasma with antibody titer alone, routine treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tehran University of Medical Sciences |
|
Iran |
2020-10-11 |
|
IR.TUMS.MEDICINE.REC.1399.436, IRCT20201004048922N1 |
Phase 3 Clinical |
Recruiting |
1 |
|
75 |
Hamidreza Abtahi, Mohammadali Sahraeiyan, Mohammadreza Salehi, Parisa Kianpour |
2020-10-13 |
| Study of resistance to COVID-19 of medical staff (Pilot Study) |
Acute stress disorder, Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
|
Japanese Ministry of Health, Labor and Welfare |
Japan |
2020-09-25 |
|
UMIN000042061 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
165 |
Hirayasu Kai, Kunihiro Yamagata |
2020-10-14 |
| Perception Of Dentists On Infection Control Measures During Novel Corona Virus (COVID-19) Pandemic |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Manipal College of Dental Sciences |
|
India |
2020-10-25 |
|
CTRI/2020/10/028295 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
400 |
Dr Neetha Shenoy |
2020-10-13 |
| CoTroxCov Study: Cotrimoxazole in hospitalised patients with moderate to early-severe COVID-19 infection |
Coronavirus disease 19 infection |
cotrimoxazole alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Ministry of Health and Family Welfare |
|
India |
2020-10-26 |
|
CTRI/2020/10/028297, CoTroxCov Study, U1111-1259-2654 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
200 |
Dr Santanu Kumar Tripathi |
2020-10-14 |
| COVID-19, Prediction Model, Prognosis |
Coronavirus disease 19 infection |
prediction model alone |
|
|
Hospital Sungai Buloh |
|
Malaysia |
2020-10-15 |
2022-09-15 |
56523, NMRR-20-2149-56523 |
Phase Not Applicable |
Status not specified |
1 |
23 Months |
1500 |
DR THARMINI A/P RAVI, Dr Sharifah Khairul Atikah |
2020-10-13 |
| COVIDstroke: Effect of COVID-19 pandemic on stroke admission trend in Malaysia |
Coronavirus disease 19 infection, Stroke |
|
|
|
Sultanah Nur Zahirah Hospital |
|
Malaysia |
2020-11-01 |
2021-03-31 |
1, 56595, COVIDstroke, NMRR-20-2148-56595 |
Phase Not Applicable |
Not yet recruiting |
1 |
5 Months |
|
Mrs NORSIMA NAZIFAH SIDEK |
2020-10-13 |
| PoCoPoHo: Post COVID-19 Infection: Impact of Clinical Severity and Timeline on Functional Status, Symptomology and Serological Status Post-Hospitalization |
Coronavirus disease 19 infection |
|
|
|
Hospital Raja Permaisuri Bainun |
|
Malaysia |
2020-10-01 |
2020-10-31 |
NMRR-20-2125-56457, PoCoPoHo |
Phase Not Applicable |
Status not specified |
1 |
1 Month |
|
MOH CHENG KEAT |
2020-10-13 |
| Antibiotic-COVID-19 |
Coronavirus disease 19 infection |
antibiotics alone |
|
|
Hospital Raja Permaisuri Bainun |
|
Malaysia |
2020-10-12 |
2020-11-17 |
56531, NMRR-20-2124-56531 |
Phase Not Applicable |
Status not specified |
1 |
1 Month |
|
Dr Izzati Nadhirah Bt Mohamad |
2020-10-20 |
| Intranasal administration of recombinant human interferon alfa-2b as prophylaxis of SARS-CoV-2 infection. (COVID-19) |
Coronavirus disease 19 infection |
nasalferon alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Center for Genetic Engineering and Biotechnology |
|
Cuba |
2020-10-12 |
2020-11-06 |
IG / IAGN / VS / 2001, RPCEC00000337 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
|
80 |
Francisco Hernandez Bernal, Leader Josué Diaz |
2020-10-13 |
| A prospective study of CoVerity in the diagnosis of severe respiratory failure risk in patients with PCR-confirmed SARS-CoV-2 pneumonia |
Coronavirus disease 19 infection |
CoVerity COVID-19 Severity Test alone |
|
|
Inflammatix Inc |
|
Greece |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
97 |
|
2020-10-12 |
| Understanding Immunity to the Flu Vaccine in COVID-19 Patients |
Coronavirus disease 19 infection |
flu vaccine alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Stanford University |
National Institute of Allergy and Infectious Diseases |
US |
2020-12-01 |
2022-12-01 |
5U19AI057229-17, IRB-58356, NCT04579588 |
Phase Not Applicable |
Not yet recruiting |
1 |
24 Months |
80 |
Hena Din, Kari Nadeau, MD, PhD |
2020-10-12 |
| Fostamatinib for Hospitalized Adults With COVID-19 |
Coronavirus disease 19 infection |
fostamatinib disodium alone, standard of care alone |
Syk tyrosine kinase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Heart Lung and Blood Institute |
Inova Health Care Services, National Institutes of Health Clinical Center |
US |
2020-10-08 |
2020-12-15 |
000110-H, 10000110, NCT04579393 |
Phase 2 Clinical |
Recruiting |
3 |
2 Months |
60 |
Edwinia Battle, Jeffrey R Strich, M.D., Jennifer J Kyte, D.N.P. |
2020-10-23 |
| EPID CLUSTER: Study of COVID-19 Clusters in Pahang |
Coronavirus disease 19 infection |
|
|
|
Jabatan Kesihatan Negeri Pahang |
|
Malaysia |
2020-10-06 |
2020-10-21 |
55739, EPID CLUSTER, NMRR-20-2162-55739 |
Phase Not Applicable |
Status not specified |
1 |
|
|
Dr WAN ABDUL RAHIM B WAN MUHAMMAD |
2020-10-12 |
| SeCuRE Study: Social isolation, depression, anxiety and resilience among older adults in Klang Valley during the COVID-19 crisis |
Anxiety disorder, Coronavirus disease 19 infection, Depression |
|
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Selayang Hospital |
|
Malaysia |
2020-11-02 |
2022-01-03 |
55538, NMRR-20-2169-55538, SeCuRE Study |
Phase Not Applicable |
Not yet recruiting |
2 |
14 Months |
|
Dr Zanariah Mat Saher, Dr. Nor Jannah Nasution Raduan |
2020-10-12 |
| CORONAVIT: Trial of Vitamin D to Reduce Risk and Severity of COVID-19 and Other Acute Respiratory Infections |
Coronavirus disease 19 infection, Respiratory tract infection |
vitamin D alone |
|
Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Queen Mary University of London |
Barts Charity, Pharma Nord ApS |
UK |
2020-10-19 |
2021-06-30 |
289515, CORONAVIT, NCT04579640 |
Phase 3 Clinical |
Not yet recruiting |
1 |
8 Months |
5440 |
Adrian R Martineau, MD PhD, David A Jolliffe, PhD |
2020-10-12 |
| Assessment of COVID-19 in Tearfilm |
Coronavirus disease 19 infection |
biological sampling alone, biopsy alone, fluorescein angiography alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Vanderbilt University Medical Center US |
|
US |
2020-10-09 |
2021-05-09 |
201127, NCT04579458 |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
500 |
Sapna Gangaputra |
2020-10-13 |
| Repeat Testing for SARS-CoV-2 |
Coronavirus disease 19 infection |
RT-LAMP Assay alone, Saliva assay test alone |
|
Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Wisconsin-Madison |
National Institutes of Health |
US |
2020-09-29 |
2021-09-30 |
2020-1142, 5P51OD011106-59, A536300, NCT04579549, PROTOCOL VERSION 8/17/2020, SMPH/PATHOL-LAB MED/ANAT PATH |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
10000 |
David O'Connor, PhD |
2020-10-14 |
| Study on use of Homoeopathy Medicines in Treatment of Covid 19 cases |
Coronavirus disease 19 infection |
Homoeopathy medicine alone |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Ministry of Ayush |
|
India |
2020-10-10 |
|
CTRI/2020/10/028233 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
60 |
Dr SUGATHAN N V |
2020-10-14 |
| REMPAR-EHPAD: Managerial and Environmental Risk for COVID 19 in French Long-Term Care Institutions |
Coronavirus disease 19 infection |
|
|
|
Rennes University Hospital |
|
France |
2020-06-15 |
2020-09-01 |
35RC20_8898_REMPAR-EHPAD, NCT04579289, REMPAR-EHPAD |
Phase Not Applicable |
Completed |
1 |
2 Months |
230 |
Aline MD CORVOL |
2020-10-14 |
| COVITRA: Prevalence and Outcome of SARS-CoV-2 Infection and COVID-19 in Transplant Recipients |
Coronavirus disease 19 infection, Hematopoietic stem cell transplantation, Organ transplantation |
SARS-CoV-2 IgG test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universitaire Ziekenhuizen Leuven |
Jessa Hospital, Katholieke Universiteit Leuven, Universiteit Hasselt, Ziekenhuis Oost-Limburg |
Belgium |
2020-07-01 |
2021-12-31 |
COVITRA, NCT04579471, S64036 |
Phase Not Applicable |
Recruiting |
1 |
18 Months |
2000 |
Jef Verbeek, MD, Jef Verbeek, MD, PhD, Natalie Van den Ende, Natalie Vandenende |
2020-10-12 |
| Psychological effect of coronavirus disease 2019 on pregnant women |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs) |
All India Institute of Medical Sciences |
|
India |
2020-10-14 |
|
CTRI/2020/10/028232 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
25 |
Dr Poonam Kumari |
2020-10-12 |
| Proof of Concept Study of Ketoji (Liquid) for its Effectiveness in Treatment and Management of COVID-19 Patients |
Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory tract infection |
Ketoji alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Ruby Hall Clinic |
|
India |
2020-10-12 |
|
BPLS/KTJ/2020, CTRI/2020/10/028231 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
15 |
Dr Kapil G Zirpe, Ms Pranjal Ausekar |
2020-10-15 |
| Clinical trial of Pippali Rasayana and Nagaradi Kashaya Ghana Vati combination as an adjuvant treatment with ICMR guided medicines in Covid-19 positive mildly symptomatic cases |
Coronavirus disease 19 infection |
ICMR directed therapy alone, Variable regimens including Nagaradi Kashaya Ghana Vati , Pippali Rasayana , Rasayana Kala , Vyanodana Kala |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
PAED'S Ayurved Rugnalaya and Sterling Multispeciality Hospital |
|
India |
|
|
CTRI/2020/10/028230 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
60 |
Dr Medha Mahesh Joshi, DrYogita Abhijit Jamdade |
2020-10-12 |
| A first-in-human clinical trial of ivermectin (oral, COVID-19), MedinCell for COVID-19 |
Coronavirus disease 19 infection |
ivermectin (extended release/sc/BEPO, COVID-19), MedinCell alone |
|
|
MedinCell SA |
|
|
2020-09-29 |
|
|
Phase Not Applicable |
Recruiting |
0 |
|
|
|
2020-10-20 |
| Corticosteroids in COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
dexamethasone alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tehran University of Medical Sciences |
|
Iran |
2020-09-26 |
|
IR.TUMS.MEDICINE.REC.1399.430, IRCT20100228003449N31 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
|
119 |
Hossein Khalili, Mohammad Ali Sahraian |
2020-10-12 |
| FACIAL HAIR: Facial Hair, PPE and COVID-19 |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted |
Royal Cornwall Hospitals Trust |
|
UK |
2020-05-14 |
2020-06-08 |
283609, FACIAL HAIR, NCT04579627 |
Phase Not Applicable |
Completed |
1 |
|
358 |
|
2020-10-12 |
| RECEDE: Regional COVID Epidemiology in England |
Coronavirus disease 19 infection, Renal injury |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospitals Of Derby and Burton NHS Foundation Trust |
|
UK |
2020-11-01 |
2021-10-31 |
NCT04579562, RECEDE, UHDB/2020/075 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
5000 |
Nitin V Kolhe, DM |
2020-10-13 |
| A study to know whether investigators can supervise cancer patients infected with COVID-19 from without admission in hospitals. Investigators will test how much helpful is a software called Datos health along with pulse oximeter and thermometer in this supervision by doctors |
Coronavirus disease 19 infection |
Datos Platform alone, pulse oximeter alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tata Memorial Hospital |
|
India |
2020-10-13 |
|
CTRI/2020/10/028256 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
30 |
Dr Manju Sengar |
2020-10-12 |
| Psychological Impacts Of The COVID-19 Pandemic On Medical Students In India: A Web-Based Cross-Sectional Study |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs) |
Sri Ramachandra Institute of Higher Education and Research |
|
India |
2020-10-10 |
|
CTRI/2020/10/028257 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
500 |
Dr S Natarajan, Ria Tyagi |
2020-10-12 |
| Feasibility study of a mobile device for the prevention of sepsis in patients with solid tumors after chemotherapy and patients with infectiose diseases (COVID-19) |
Coronavirus disease 19 infection, Respiratory tract infection, Sepsis |
VitalPatch alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universitätsklinikum Frankfurt Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie |
HMS Analytical Software GmbH |
Germany |
2019-08-02 |
|
DRKS00017593, FF136/2018 |
Phase Not Applicable |
Recruiting |
1 |
|
50 |
Mate Knabe |
2020-10-20 |
| CAMMS: Inhibiting transmission of respiratory viruses |
Coronavirus disease 19 infection |
nutraceuticals alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
|
|
India |
2020-11-01 |
|
CAMMS, CTRI/2020/10/028255 |
Phase 2 Clinical |
Not yet recruiting |
2 |
|
200 |
Dr Suman Kapur, Dr Vibhor Tak |
2020-10-12 |
| PregCOVID: Retrospective Study of Pregnancy with COVID-19 |
Coronavirus disease 19 infection |
|
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Dr TMA Pai Hospital |
|
India |
2020-10-08 |
|
CTRI/2020/10/028254, PregCOVID |
Phase Not Applicable |
Not yet recruiting |
1 |
|
44 |
Shashikala Bhat |
2020-10-12 |
| Correlation Between Thoracic Ultrasound and Thorax Computed Tomography Scores |
Coronavirus disease 19 infection, Viral pneumonia |
lung ultrasound (LUS) alone, thorax computed tomography (CT) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Gaziosmanpasa Taksim Research and Education Hospital |
|
Turkey |
2020-06-05 |
2020-09-05 |
AYŞEV, NCT04577235 |
Phase Not Applicable |
Completed |
1 |
3 Months |
29 |
Ayşe Vahapoglu, M.D |
2020-10-12 |
| Effect of CBT Intervention to Improve Sleep on Wellbeing, Dietary Intake and Food Preference |
Coronavirus disease 19 infection, Insomnia |
cognitive behavioral therapy alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
University of Glasgow |
|
UK |
2020-10-05 |
2021-06-01 |
200190177, NCT04576260 |
Phase Not Applicable |
Not yet recruiting |
2 |
7 Months |
40 |
Ayan Merchant, MSc, Ayan Merchant, MSc., Cindy Gray, PhD, Jason Gill, PhD, Stuart Gray, PhD |
2020-10-13 |
| An observational, single-center, cohort study to evaluate the association between treatment with colchicine and improved survival of adult hospitalized patients with COVID-19 pneumonia and acute respiratory distress syndrome |
Coronavirus disease 19 infection, Respiratory distress syndrome |
colchicine alone, dexamethasone alone, hydroxychloroquine alone, lopinavir + ritonavir alone, standard of care alone, Variable regimens including dexamethasone , hydroxychloroquine , lopinavir + ritonavir |
HIV protease inhibitor |
|
|
|
Italy |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
262 |
|
2020-10-12 |
| Q-TIP: Comparison between certified swab systems (Copan eSwab) and commercially available cotton swabs ('Q-Tip') for the detection of multi-resistant pathogens (MRE) using rectal swabs |
Coronavirus disease 19 infection, Infectious disease |
Ebelin Q-Tip cotton swab alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
UniversitätsKlinikum Leipzig |
|
Germany |
2020-09-20 |
|
327/20-ek, DRKS00023249, Q-TIP |
Phase Not Applicable |
Recruiting |
1 |
|
600 |
Johannes Wiegand |
2020-10-13 |
| Corona CPR: Impact of personal protective equipment (PPE) during a simulated cardiac arrest in times of the COVID-19 pandemic |
Cardiac arrest, Coronavirus disease 19 infection |
FFP2 personal protective equipment use alone, simulated resuscitation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Arbeitsgemeinschaft Intensivmedizin e.V |
|
Germany |
2020-09-20 |
|
2020-602-f-S, Corona CPR, DRKS00023184 |
Phase Not Applicable |
Recruiting |
1 |
|
400 |
Stephan Marsch, Timur Sellmann |
2020-10-12 |
| Effect of spiritual care based on Ghalbe Salim on anxiety related to COVID-19 (corona phobia) |
Anxiety disorder, Coronavirus disease 19 infection, Phobia |
Ghalbe Salim model based spiritual program alone |
|
Female |
|
|
Iran |
2020-05-23 |
2020-07-31 |
IR.LARUMS.REC.1399.001, IRCT20201003048905N1 |
Phase Not Applicable |
Completed |
1 |
2 Months |
14 |
Dr Behzad Rezaie, Zohreh Faramarzian |
2020-10-09 |
| Randomized, phase II clinical trial to evaluate safety and efficacy of the use of plasma from convalescent patients with the new coronavirus disease (COVID-19) for the experimental treatment of patients hospitalized in the centro medico naval 'cirujano mayor santiago tavara' |
Coronavirus disease 19 infection |
convalescent plasma alone, standard hospital treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
NAVY OF WAR OF PERU |
|
Peru |
2020-09-07 |
|
CEMENA-20-01 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
100 |
César José Suárez De Armero, José Martín Avilés Calderón, MARIO ORTIZ MONDRAGÓN, Max Grogl |
2020-10-20 |
| SALICOV: Evaluation of a Screening Program for SARS-CoV-2 Infection in the General Population Based on the Use of New Detection Approaches or for Diagnostic Orientation on Saliva |
Coronavirus disease 19 infection |
saliva sampling alone |
|
|
Assistance Publique Hopitaux de Paris |
|
France |
2020-10-31 |
2021-06-30 |
2020-A02431-38, APHP200960, NCT04578509, SALICOV |
Phase Not Applicable |
Not yet recruiting |
1 |
8 Months |
2750 |
Jérôme Le Goff, Professor, LE GOFF Jérôme, Professor, Laure Choupeaux, Master, Solen Kernéis, Doctor, Solen Kernéis, MD, PhD |
2020-10-12 |
| SOGUGCOVID: Description of the Population With Genitourinary Tumors and COVID-19 |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Spanish Oncology Genito-Urinary Group |
|
Spain |
2020-09-30 |
2021-10-31 |
NCT04578132, SOG-INM-2020-04, SOGUGCOVID |
Phase Not Applicable |
No longer recruiting |
32 |
13 Months |
250 |
Aránzazu González del Alba, M.D., Ph.D., Javier Puente, M.D., Ph.D., Miguel Ángel Climent, M.D., Ph.D., Natalia Vidal, M.D., Ph.D., Sergio Vázquez Estevez, M.D., Ph.D. |
2020-10-12 |
| TMPRSS2: Efficacy of Aerosol Combination Therapy of 13 Cis Retinoic Acid and Captopril for Treating Covid-19 Patients Via Indirect Inhibition of Transmembrane Protease, Serine 2 |
Coronavirus disease 19 infection |
13 cis retinoic acid plus captopril |
ACE inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kafrelsheikh University |
|
Egypt |
2020-11-30 |
2021-01-31 |
NCT04578236, SARS, TMPRSS2 |
Phase 2 Clinical |
Not yet recruiting |
1 |
2 Months |
360 |
Mahmoud Elkazzaz, B.Sc,M.Sc in Biochemistry |
2020-10-12 |
| Future Health Today: A cluster randomized controlled trial of quality improvement activities in general practice |
Cancer, Coronavirus disease 19 infection, End stage renal disease |
ECHO (Extension for Community Healthcare Outcomes) education alone, Future Health Today alone, cancer FHT module alone, chronic kidney disease (CKD) FHT module alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cancer Research UK, NHMRC Clinical Trials Centre, Paul Ramsay Foundation, University of Melbourne |
|
Australia |
2020-12-18 |
2021-08-31 |
2056564, ACTRN12620000993998, ANZCTR380119, U1111-1254-1693 |
Phase Not Applicable |
Not yet recruiting |
2 |
8 Months |
8000 |
A/Prof Jo-Anne Manski-Nankervis |
2020-10-17 |
| A phase I clinical trial for inactivated SARS-CoV-2 Vaccine(Vero Cells) |
Coronavirus disease 19 infection |
COVID-19 vaccine (inactivated/Vero cells/intramuscular, SARS-CoV-2 infection), Shenzhen Kangtai Biological Products alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Jiangsu Province Centers for Disease Control and Prevention |
|
China |
2020-10-07 |
2022-04-06 |
ChiCTR2000038804 |
Phase 1 Clinical |
Not yet recruiting |
2 |
18 Months |
180 |
Li Guifan, Pan Hongxing |
2020-10-19 |
| A clinical trial to test the effectiveness of thalidomide in reducing immune dysfunction in covid-19 disease |
Autoimmune disease, Coronavirus disease 19 infection |
thalidomide, Celgene alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Ruby Hall Clinic |
|
India |
2020-10-10 |
|
CTRI/2020/10/028253 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
20 |
Dr Abhijit R Lodha |
2020-10-09 |
| A Study to Evaluate Efficacy of Selected Homoeopathic Medicines in Prevention of COVID-19 |
Coronavirus disease 19 infection |
Variable regimens including Arsenic album , Bryonia alba , Camphora |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Ministry of Ayush |
|
India |
2020-10-15 |
|
CTRI/2020/10/028280 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
18000 |
Dr Meeta Gupta, Dr Raj K Manchanda |
2020-10-09 |
| Standard of care with homoeopathy as adjuvant in COVID19 |
Coronavirus disease 19 infection |
Homoeopathic medicine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
All India Institute of Medical Sciences |
|
India |
2020-10-12 |
|
CTRI/2020/10/028279 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
128 |
Dr Sushma Bhatnagar |
2020-10-09 |
| COVID-19 and children with congenital heart disease |
Congenital heart defect, Coronavirus disease 19 infection |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
All India Institute of Medical Sciences |
|
India |
2020-10-15 |
|
CTRI/2020/10/028251 |
Phase Not Applicable |
Not yet recruiting |
33 |
|
50 |
Avinash Anantharaj, C S Muthukumaran, Dr Devaprasath, Dr Dharmendra Jain, Dr Gnanasambandan, Dr H ravi Ramamurthy, Dr Harmeet Singh Arora, Dr Jabaraj, Dr Jayashree Mishra, Dr Joseph Xavier, Dr K Sivakumar, Dr Kalyanasundaram, Dr M Jayranganath, Dr Mahesh K, Dr Manoj K Rohit, Dr P V Suresh, Dr Prabhatha Rashmi Murthy, Dr Prashant Mahawar, Dr Prashant Shah, Dr Rema Devi, Dr S Ramakrishnan, Dr Saileela, Dr Sanjay Khatri, Dr Smit Shrivastava, Dr Snehal Kulkarni, Dr Srinivas Lakshmivenkateshiah, Dr Swati Garekar, Edwin Francis, K M Krishnamoorthy, Kavya Mallikarjun, Prabhatha Rashmi Murthy, Rishi Sethi, Suresh Kumar |
2020-10-21 |
| The Knowledge, Attitude And Practices related to COVID-19 in Patients Presenting to Glaucoma Clinic and the Reasons for seeking Glaucoma care |
Coronavirus disease 19 infection, Glaucoma |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Aravind Eye Hospital - Pondicherry |
|
India |
2020-10-12 |
|
CTRI/2020/10/028278 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
246 |
Dr AnnamalaiO, Dr Kavitha S, Dr Venkatesh R, Kalluri Satya Srividya |
2020-10-09 |
| A study to evaluate the effects of stem cells in patients with acute respiratory distress syndrome caused by pneumonia due to COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia |
Stempeucel alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Indian Council of Medical Research, Ministry of Health and Family Welfare |
|
India |
2020-10-14 |
|
CTRI/2020/10/028250, ICMR/ARDS/20-21/001 |
Phase 2 Clinical |
Not yet recruiting |
2 |
|
40 |
Dr Geeta Jotwani, Dr Manoj Kumar Panigrahi, Dr Pawan Kumar Gupta, Dr Sharat Damodar |
2020-10-09 |
| Effect of N95 mask on general condition and respiration of health care workers |
Coronavirus disease 19 infection |
N95 FFRs alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Hamdard Institute of Medical Sciences & Research (HIMSR) |
|
India |
2020-10-19 |
|
CTRI/2020/10/028249 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
30 |
Sana Yasmin Hussain |
2020-10-09 |
| PPI: Stress-free after corona: a psychological help program |
Acute stress disorder, Coronavirus disease 19 infection, Psychiatric disorder |
behaviour modification technique based intervention alone, group-based face-to-face intervention alone, home based progressive muscle relaxation exercise alone, home based work sheet exercise alone, low-threshold online digital intervention alone, model deduction intervention alone, parenting strategies based intervention alone, psychoeducation alone |
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Humboldt University of Berlin |
|
Germany |
2020-09-01 |
|
2020-35, DRKS00023220, PPI |
Phase Not Applicable |
Recruiting |
1 |
|
400 |
Ulrike Luken |
2020-10-12 |
| A study to assess the safety and effectiveness of Thymosin alpha-1 (Talpha1) used for the treatment of Moderate to severe COVID 19 Patients |
Coronavirus disease 19 infection |
Thymosin alpha alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Gufic Bioscience Ltd |
|
India |
2020-10-12 |
|
CTRI/2020/10/028277, GB_THY_001_20 |
Phase 3 Clinical |
Not yet recruiting |
7 |
|
120 |
Dr Adarsh Shetty, Dr Arti Shah, Dr Dev Nath Jha, Dr Giridhar Patil, Dr Nirhali Sonali Chandrakant, Dr Rahul Ashok Darnule, Dr S K Sonkar, DrPrachee Milind Sathe, Mr Vairamuthu Ammaiyappan |
2020-10-09 |
| Chest Radiographic Findings of Adult Patients with Confirmed Coronavirus Disease 2019 (COVID-19) at Southern Philippines Medical Center |
Coronavirus disease 19 infection |
|
|
|
Southern Philippines Medical Center |
|
Philippines |
2020-10-01 |
2020-12-15 |
PHRR201001-002988 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
|
Maria Theresa T. Sanchez, MD, FPCR, Nalvic De Chavez |
2020-10-09 |
| A mHealth-based randomized controlled trial for improving mental health among people living with HIV during the COVID-19 outbreak |
Coronavirus disease 19 infection, Depression, HIV infection |
Articles and audios alone, WeChat-based Cognitive-Behavior and Stress Management course alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sun Yat-Sen University |
|
China |
2020-10-15 |
2021-12-31 |
ChiCTR2000038866 |
Phase 0 Clinical |
Not yet recruiting |
1 |
14 Months |
|
Yan Guo, Yu Zeng |
2020-10-09 |
| A Randomized, Double-blind, Placebo-controlled, Phase Ib/II Clinical Study to Evaluate the Preliminary Efficacy, Safety, Pharmacokinetic Profiles and Immunogenecity of JS-016 (Recombinant Human Anti-SARS-CoV-2 Monoclonal Antibody) Given as Intravenous Infusion in Participants with Mild and Moderate COVID-19 or of SARS-CoV-2 Asymptomatic Infection |
Coronavirus disease 19 infection |
etesevimab alone |
COVID19 Spike glycoprotein inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
PAREXEL Clinical Research, Shanghai Junshi Biosciences Co Ltd |
|
China, Philippines, Hong Kong, Russian Federation, Ukraine, Singapore |
2020-09-30 |
2021-06-30 |
2020-CT0565, JS016-002-Ib/II, PHRR201001-002968 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
7 |
9 Months |
25 |
Chriziel Escaño, Fatima Gugova, Joel M. Santiaguel, MD, Maria Tarcela Gler, MD |
2020-10-09 |
| Does elective orthopaedic surgery in the pandemic era increase the risk of developing COVID-19? A combined analysis of retrospective and prospective study at a national tertiary hospital in Jakarta, Indonesia |
Coronavirus disease 19 infection, Viral pneumonia |
elective orthopedic surgery alone |
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
University of Indonesia |
|
Indonesia |
2020-07-01 |
2020-08-31 |
ChiCTR2000038865 |
Phase Not Applicable |
No longer recruiting |
1 |
2 Months |
|
Achmad Fauzi Kamal, I Wayan Arya Mahendra Karda |
2020-10-12 |
| Study on the risk perception, mental health, and behavioural responses of university students in Hong Kong in COVID-19 pandemic |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs) |
Chinese University of Hong Kong |
|
China |
2020-10-19 |
2022-12-31 |
ChiCTR2000038864 |
Phase Not Applicable |
Not yet recruiting |
1 |
26 Months |
600 |
Queenie Hoi Wing WONG |
2020-10-09 |
| MALCOV: Malaria as a risk factor for COVID-19 in western Kenya and Burkina Faso |
Coronavirus disease 19 infection, Plasmodium infection |
pyronaridine +artesunate alone |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Liverpool School of Tropical Medicine, London School of Hygiene and Tropical Medicine |
Bill & Melinda Gates Foundation, Centers for Disease Control and Prevention, Groupe de Recherche Action en Santé (GRAS), Kenya Medical Research Institute |
Burkina Faso, Kenya |
2021-01-11 |
|
MALCOV, PACTR202009642148520 |
Phase 2 Clinical |
Not yet recruiting |
4 |
|
142 |
Chris Drakeley, Feiko ter Kuile, Hellen Barsosio, Simon Kariuki, Sodiomo Sirima |
2020-10-09 |
| The COVID-19 Community Engagement Study |
Coronavirus disease 19 infection |
community-owned risk communication intervention alone |
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Makerere University |
|
Uganda |
2020-10-05 |
|
PACTR202010729372570 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
800 |
Daniel Semakula, Nelson Sewankambo |
2020-10-09 |
| Interobserver variability and correlation with clinical outcomes in assessing COVID-19 related chest X-ray findings using the Brixia scoring system |
Coronavirus disease 19 infection |
|
|
|
Philippine General Hospital |
|
Philippines |
2020-06-01 |
2020-09-28 |
PHRR200929-002986 |
Phase Not Applicable |
Completed |
1 |
3 Months |
|
Jorrel Vincent Valdez, MD, FPCR, Michelle Regina Castillo, MD, Rovi Niño D. Samedra, MD, FPCR |
2020-10-12 |
| A case report on COVID-19 inflammatory syndrome with clinical features resembling Kawasaki disease |
Coronavirus disease 19 infection, Kawasaki disease |
IVIg alone, corticosteroids alone |
|
Male |
Columbia University, New York Presbyterian Hospital |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
2 |
|
2020-10-08 |
| A phase III clinical study to assess two-dose regimen of JNJ-78436735 compared to placebo in the treatment of patients with SARS-CoV-2 infection |
Coronavirus disease 19 infection |
JNJ-78436735 alone |
|
|
Johnson & Johnson |
|
|
|
|
|
Phase 3 Clinical |
Planned |
0 |
|
|
|
2020-10-19 |
| RELEASE: Safety Infusion of Natural Killer Cells or Memory T-Cells as Adoptive Therapy in COVID-19 Pneumonia or Lymphopenia |
Coronavirus disease 19 infection, Lymphocytopenia, Viral pneumonia |
allogeneic NK cells alone, allogeneic T memory cells alone |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Instituto de Investigación Hospital Universitario La Paz |
Asociación Instituto de Investigación Sanitaria BioCruces, Foundation for Health Research and Biomedical Valencia, Universidad Autonoma de Madrid, Universidad Miguel Hernandez de Elche |
Spain |
2020-09-04 |
2021-03-31 |
NCT04578210, RELEASE, RELEASE |
Phase 1/Phase 2 Clinical |
Recruiting |
1 |
6 Months |
58 |
Antonio Pérez Martínez, Dr, Bernat Soria, Dr, Carlos Solano, Dr, Cristina Eguizabal, Dra, Víctor Alelú Hernández, Mr |
2020-10-21 |
| CARE+: Covid-19-associated research on hand eczema in the health sector – Part 1 |
Coronavirus disease 19 infection, Eczema |
health education training alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
iDerm an der Universität Osnabrück |
|
Germany |
2020-11-08 |
|
Bo/34/2020, CARE+, DRKS00022957, DRKS00022958 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
260 |
Cara Symanzik |
2020-10-09 |
| Care +: Covid-19-associated research on hand eczema in the health sector – Part 2 |
Coronavirus disease 19 infection, Eczema |
DGUV skin washer alone, lipid-containing skin cleanser alone, standard cleanser alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
iDerm an der Universität Osnabrück |
|
Germany |
2021-01-04 |
|
Bo/35/2020, Care +, DRKS00022957, DRKS00022958 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
35 |
Cara Symanzik |
2020-10-09 |
| A trial to evaluate a new COVID-19 rapid test for diagnosis of COVID-19 |
Coronavirus disease 19 infection |
COVID-19 rapid test alone |
|
|
Graphene Leaders Canada Inc |
|
Canada |
|
|
|
Phase Not Applicable |
Planned |
1 |
|
|
|
2020-10-08 |
| Trial to Study the Adjuvant Benefits of Quercetin Phytosome in Patients With COVID-19 |
Coronavirus disease 19 infection, Inflammatory disease, Respiratory disease, Respiratory distress syndrome, Respiratory failure |
Quercetin Phytosome plus remdesivir |
COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Liaquat University of Medical & Health Sciences |
|
Pakistan |
2020-10-26 |
2021-04-25 |
LUMHS/REC/894, NCT04578158 |
Phase 2 Clinical |
Not yet recruiting |
1 |
6 Months |
200 |
Prof. Dr. Ikram Din Ujjan, Prof. Dr. Ikram Din Ujjan, MBBS, PhD, Prof. Dr. Saeed Khan |
2020-10-20 |
| A clinical trial of HOUND COVID-19 Breathalyzer, the world's first portable breathalyzer to capture SARS-CoV-2 virus in breath of human test subjects |
Coronavirus disease 19 infection |
HOUND COVID-19 BREATHALYZER alone |
|
|
Hound Labs Inc |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-10-16 |
| For covid-19 infection prevention measures in sport |
Coronavirus disease 19 infection |
exercise test alone, football helmets alone |
|
Healthy volunteers accepted, Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
St Marianna University School of Medicine |
|
Japan |
2020-09-09 |
|
UMIN000042034 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
5 |
Hiroto Fujiya, Ryota Muroi |
2020-10-09 |
| NeuroCovid: A Study of Intensive Care-requiring Covid-19 Patients |
Cognitive disorder, Coronavirus disease 19 infection, Encephalitis |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Karolinska University Hospital |
Karolinska Institutet |
Sweden |
2020-08-18 |
2022-11-30 |
DNR 2020-02760, NCT04578197, NeuroCovid |
Phase Not Applicable |
Recruiting |
1 |
27 Months |
100 |
Lars I Eriksson, Prof, Lars I Eriksson, Professor, Mia Kivipelto, Professor |
2020-10-09 |
| CEM: Melatonin in COVID-19 |
Coronavirus disease 19 infection, Inflammatory disease |
Variable regimens including acetaminophen , hydroxychloroquine , melatonin (Elite factory) , naproxen |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Tehran University of Medical Sciences |
|
Iran |
2020-08-05 |
|
CEM, IR.TUMS.VCR.REC.1399.068, IRCT20200922048804N1 |
Phase 2 Clinical |
No longer recruiting |
1 |
|
20 |
Nastaran Keyhanian, Zahra Alizadeh, ِDr. Mohammad Ali Sahraian |
2020-10-12 |
| Health Care Worker's Perception of Patient Safety During COVID-19 Pandemic |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universidad Miguel Hernandez de Elche |
Pontificia Universidad Catolica De Chile, Universidad Antonio Nariño, Universidad Catolica Santiago de Guayaquil, Universidad de Santander, University of Sao Paulo |
Chile, Spain, Colombia, Ecuador |
2020-09-01 |
2020-12-15 |
2020-09, NCT04576299 |
Phase Not Applicable |
No longer recruiting |
4 |
3 Months |
800 |
Jose J Mira, PhD |
2020-10-11 |
| NeuroCovid: The Norwegian Study of Nervous System Manifestations and Sequelae After COVID-19 |
Coronavirus disease 19 infection, Psychiatric disorder |
anti-viral drugs therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Oslo University Hospital |
Haukeland University Hospital, Helse Stavanger HF, Møre and Romsdal Hospital Trust, Nordlandssykehuset HF, Ostfold Hospital Trust, Sorlandet Hospital, St Olavs Hospital, Sykehuset Innlandet HF, Sykehuset Telemark, Sykehuset i Vestfold HF, University Hospital of North Norway, University Hospital, Akershus, Vestre Viken HF |
Norway |
2020-09-01 |
2023-12-31 |
152727, NCT04576351, NeuroCovid |
Phase Not Applicable |
Recruiting |
15 |
40 Months |
150 |
Anette Huuse Farmen, MD PhD, Anne Hege Aamodt, MD PhD, Anne Hege Aamodt, MD, PhD, Barbara Ratajczak-Tretel, MD, Christian Samsonsen, MD PhD, Guttorm Eldøen, MD, Hanne F Harbo, MD,PhD,Prof, Heidi Øyen Flemmen, MD, Hilde K Ofte, MD PhD, Linn H Steffensen, MD PhD, MD,PhD,Prof, Marion Boldingh, MD PhD, Martin Kurz, MD PhD Prof, Martin Weisshaar, MD, Mette Bergum, MD, Mona S E Skjelland, MD PhD Prof, Randi Eikeland, MD, Tormod Fladby, MD PhD Prof, Trine H Popperud, MD PhD, Trine H Popperud, MD, PhD, Øyvind G Torkildsen, MD PhD Prof |
2020-10-08 |
| Study to Assess the Safety of Ascending Doses of UNI-911 Inhalation in Healthy Volunteers in Preparation for Evaluation in Adults With COVID-19 |
Coronavirus disease 19 infection |
niclosamide (COVID-19), UNION therapeutics/ Institut Pasteur Korea alone |
S phase kinase associated protein 2 inhibitor |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
UNION therapeutics |
Denmark Technical University, The Danish National Advanced Technology Foundation, Trial Nation Denmark |
Denmark |
2020-06-29 |
2020-12-31 |
NCT04576312, UNI911-101 |
Phase 1 Clinical |
Recruiting |
3 |
6 Months |
44 |
Mads Jellingsø, Torben Balchen, Ulf Sjöbring, MD, Wanja Nyoro |
2020-10-24 |
| A clinical study of novel and proprietary Aerosolized Delivery System (ADS) to aerosolize and deliver the KL4 surfactant noninvasively in COVID-19 patients that are at high risk of respiratory failure with an intent to avoid mechanical ventilation |
Coronavirus disease 19 infection |
Aerosurf (Aerosolized Delivery System) alone, lucinactant (aerosol), Windtree Therapeutics/ Esteve/ Lee's Pharmaceutical alone |
BMP10 gene inhibitor, BMP15 gene inhibitor |
|
Windtree Therapeutics Inc |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-10-07 |
| A study to fully assess the impact of KL4 surfactant on clinical endpoints such as time on mechanical ventilation, time in the ICU, mortality in COVID-19 patients who are intubated and mechanically ventilated for associated lung injury and ARDS |
Coronavirus disease 19 infection, Lung injury, Respiratory distress syndrome |
lucinactant (aerosol), Windtree Therapeutics/ Esteve/ Lee's Pharmaceutical alone |
BMP10 gene inhibitor, BMP15 gene inhibitor |
|
Windtree Therapeutics Inc |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
|
|
2020-10-09 |
| ADVISe: Longitudinal Imaging of Microglial Activation in Different Clinical Variants of Alzheimer's Disease |
Alzheimers disease, Amnesia, Aphasia, Atrophy, Coronavirus disease 19 infection, Inflammatory disease |
11C-ER-176 alone, Lumbar puncture alone, MK-6240-[18F] alone, MRI alone, PET scan alone, florbetaben (18F) alone |
Beta amyloid modulator |
Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Columbia University |
National Institute on Aging |
US |
2020-11-01 |
2025-05-31 |
AAAS7810, ADVISe, NCT04576793, R01AG063888 |
Phase 2 Clinical |
Recruiting |
1 |
55 Months |
100 |
Aubrey S Johnson, William C Kreisl, MD, Zeljko Tomljanovic, MD |
2020-10-09 |
| The effect of cardiac massage training in patients with cardiac arrest with COVID-19 positioned in the ventral position |
Cardiac arrest, Coronavirus disease 19 infection, Respiratory disease |
cardiac massage training alone, chest compression alone, instructional video alone, prone position alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universidade Federal de Sao Paulo - UNIFESP |
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior |
Brazil |
2020-08-13 |
|
31510320.4.0000.5505, 4.016.959, RBR-2xxrrq, U111112573179 |
Phase Not Applicable |
No longer recruiting |
1 |
|
1000 |
Comitê de Ética em Pesquisa, Elaine Peixoto Vieira Cavalcante, Juliana Lima Lopes |
2020-10-12 |
| The effect of chloroquine, hydroxychloroquine OR ivermectin in patients with severe manifestations of coronavirus |
Coronavirus disease 19 infection |
chloroquine difosfate alone, hydroxychloroquine sulfate alone, ivermectin alone |
Chloride channel modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universidade Federal de Roraima |
|
Brazil |
2020-05-01 |
|
30605020.7.0000.5302, 4.013.109, RBR-8h7q82 |
Phase 2 Clinical |
No longer recruiting |
1 |
|
167 |
Allex Jardim Fonseca, ruy guilherme de souza silveira |
2020-10-19 |
| Sequelae of SAR-CoV2 infection on Quality of Life and Lung |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Chulalongkorn University, Ratchadapiseksompotch Research Fund |
|
Thailand |
2020-06-11 |
2021-06-30 |
TCTR20201006001 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
100 |
Worawan Sirichana |
2020-10-09 |
| High-Resolution Computed Tomographic (HRCT) Findings among Reverse Transcription Polymerase Chain Reaction (RT-PCR) Confirmed Coronavirus Disease 2019 (COVID-19) Adult Patients in Southern Philippines Medical Center |
Coronavirus disease 19 infection |
High-Resolution Computed Tomography alone |
|
|
Southern Philippines Medical Center |
|
Philippines |
|
|
PHRR201001-003007 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
|
Roman Aldo D. Reyes |
2020-10-09 |
| Trial for collection of blood samples from healed COVID-19 patients - research and development of in-vitro diagnostics |
Coronavirus disease 19 infection |
blood sampling alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
R-Biopharm Ag |
|
Germany |
2020-10-02 |
|
20-293, DRKS00022406 |
Phase Not Applicable |
Recruiting |
1 |
|
50 |
Mr. Dr. med. Jan Heyckendorf, Mr. Markus Böhl |
2020-10-09 |
| Practices among anesthesiologists during COVID-19 pandemic; the risk and safety concerns |
Coronavirus disease 19 infection |
|
|
|
Southern Philippines Medical Center |
|
Philippines |
2020-10-01 |
|
PHRR200929-002985 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
|
Alyssa Mae D. Albano |
2020-10-07 |
| Psychological Impact of Institutional Quarantine |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
PGIMER AND DR RML HOSPITAL |
|
India |
2020-10-06 |
|
CTRI/2020/10/028194 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Pragya Sharma |
2020-10-08 |
| Risk Factors and Computed Tomography Findings in COVID-19 |
Adult respiratory distress syndrome, Coronavirus disease 19 infection, Viral pneumonia |
Siemens 256-slice multidetector tomograph (SOMATOM) alone, chest computed tomography (CT) scan alone |
|
|
Instituto Nacional de Cardiologia Ignacio Chavez |
|
Mexico |
2020-04-01 |
2020-10-01 |
20-1177, NCT04577105 |
Phase Not Applicable |
Completed |
1 |
6 Months |
233 |
Maria Elena Soto, MsC and PhD, Sergio Andres Criales Vera, MD |
2020-10-08 |
| Efficacy and Safety of Drug Combination Therapy of Isotretinoin and Some Antifungal Drugs as A Potential Aerosol Therapy for COVID-19: An Innovative Therapeutic Approach COVID-19 (Isotretinoin) |
Coronavirus disease 19 infection |
13-cis-retinoic acid plus itraconazole |
Lanosterol-14 demethylase inhibitor |
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kafrelsheikh University |
|
Egypt |
2020-10-20 |
2020-11-20 |
ISOTRETINOIN, NCT04577378 |
Phase 2 Clinical |
Not yet recruiting |
1 |
1 Month |
45 |
Mahmoud Ramadan mohamed Elkazzaz, mahmoud Elkazzaz, B.Sc of biochemistry |
2020-10-09 |
| Factors associated with Job Satisfaction, Burnout, and Turnover Intention among Family and Community Medicine Resident Physicians during the COVID-19 pandemic: A Cross-Sectional Study |
Acute stress disorder, Coronavirus disease 19 infection, Psychiatric disorder |
|
|
|
Trinity University, Trinity University of Asia |
|
Philippines |
2020-09-09 |
2021-03-09 |
PHRR201006-002996 |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
|
Aleph S. Doctora, Mel Anthony Acuavera |
2020-10-19 |
| A phase II/III, double-blind, placebo-controlled clinical trial to evaluate the safety, tolerability and efficacy of CardiolRx in hospitalized COVID-19 patients with a prior history of, or risk factors for, cardiovascular disease (CVD) |
Coronavirus disease 19 infection |
cannabidiol (nanoformulation/subcutaneous, heart failure), Cardiol Therapeutics alone |
|
|
Cardiol Therapeutics Inc |
|
US |
|
|
|
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
422 |
Dr. Arvind Bhimaraj, Dr. Barry Trachtenberg, Dr. Carsten Tschöpe, Dr. Dennis McNamara, Dr. Leslie Cooper, Dr. Matthias Friedrich, Dr. Peter Liu, Dr. Wilson Tang |
2020-10-07 |
| Intravenous Tocilizumab in the Treatment of Patients with Severe and Critical COVID-19-related Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
tocilizumab (intravenous), Roche/Chugai alone |
IL-6 receptor antagonist, IL-6 receptor modulator |
|
University of the Philippines Manila |
Philippine Council for Health Research and Development, Roche (Philippines), Inc |
Philippines |
2020-07-16 |
2021-07-15 |
2020-CT0552, CTA-2020-20-08-31, PHRR201005-003010 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
12 Months |
98 |
Aileen David Wang, MD, Albert B. Albay, Jr., MD, Dr. Eric Jason Amante, Eric Jason Amante, MD, Fresthel Monica M. Climacosa, MD, PhD, John Carlo M. Malabad, John Carlo M. Malabad, MD, PhD, Marissa M. Alejandria, MD |
2020-10-08 |
| The Wellbeing of Surgical Residents at a Tertiary Level Government Hospital during the COVID-19 Pandemic |
Coronavirus disease 19 infection |
|
|
|
Southern Philippines Medical Center |
|
Philippines |
2020-11-01 |
|
PHRR201001-002993 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
|
Ma. Theresa Monje, Philippe Michel Manalaysay |
2020-10-07 |
| A clinical trial to evaluate the effect of Wearable Technology to prevent COVID-19 complications and death for people recovering at home |
Coronavirus disease 19 infection |
Wearable Technology alone |
|
|
Albert Einstein College of Medicine, Montefiore Health System |
|
US |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
|
Jonathan D. Leff, M.D |
2020-10-07 |
| Risk factors for GI bleeding in COVID-19 patients with anti-coagulant use |
Coronavirus disease 19 infection, Gastrointestinal bleeding |
|
|
|
Chinese General Hospital and Medical Center |
|
Philippines |
2020-09-30 |
|
PHRR201001-003002 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
|
Justin Ryan L. Tan, MD |
2020-10-08 |
| Outcomes of medical management of COVID-19 patients with GI bleeding |
Coronavirus disease 19 infection, Gastrointestinal bleeding |
medical management alone |
|
|
Chinese General Hospital and Medical Center |
|
Philippines |
2020-10-01 |
2021-10-01 |
PHRR201001-003003 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
|
Justin Ryan L. Tan, MD |
2020-10-08 |
| Study of the use of ozone therapy adjunct to the treatment of Covid-19 infections |
Coronavirus disease 19 infection |
auto-hemotherapy alone, rectal ozone alone, the treatment established by the WHO alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
|
|
Brazil |
2020-07-05 |
|
30838820.2.1001.5704, 4.141.069, RBR-5v3k5d, U1111-1257-8184 |
Phase 3 Clinical |
Recruiting |
1 |
|
150 |
Maria Emilia Gadelha Serra |
2020-10-13 |
| The effectiveness of online mindfulness training on mental health and quality of work life of nurses fighting on the frontlines against COVID-19 |
Acute stress disorder, Coronavirus disease 19 infection |
Mindfulness-based stress reduction training program alone |
|
Healthy volunteers accepted |
Oroumia University of Medical Sciences |
|
Iran |
2020-09-22 |
|
IR.UMSU.REC.1399.105, IRCT20181203041832N1 |
Phase Not Applicable |
Recruiting |
1 |
|
36 |
Firouzeh Sepehrianazar, Haedeh Feizipour, Iraj Mohebbi, Naser Gharebaghi |
2020-10-08 |
| Lessons-learned - developing a strategy for outpatient care during a pandemic in Baden-Württemberg, Germany. Patient characteristics and clinical course of infections with SARS-CoV-2 |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Tubingen |
Ministerium Für Wissenschaft Forschung Und Kunst Baden-Württemberg |
Germany |
2020-10-26 |
|
698/2020BO, DRKS00023069 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
2000 |
Christian Förster, Stefanie Joos |
2020-10-08 |
| CRISIS2: A Phase II Study Assessing the Safety and Antiviral Activity of Brequinar in SARS-CoV-2 Out-patients |
Coronavirus disease 19 infection |
brequinar alone, standard of care alone |
Dehydrogenase inhibitor, Dihydroorotate dehydrogenase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Clear Creek Bio, Inc |
|
|
2020-10-15 |
2021-02-28 |
CCB-CRISIS-02, CRISIS2, NCT04575038 |
Phase 2 Clinical |
Not yet recruiting |
0 |
4 Months |
100 |
Barbara L Powers, PhD |
2020-10-08 |
| Celecoxib effects on COVID-19 patients |
Coronavirus disease 19 infection, Viral pneumonia |
celecoxib alone, routine therapy alone |
Cyclooxygenase 2 inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Zahedan University of Medical Sciences |
|
Iran |
2020-09-22 |
|
IR.ZAUMS.REC.1399.197, IRCT20200907048644N1 |
Phase 1 Clinical |
Recruiting |
2 |
|
60 |
Dr. Habib Ghaznavi, Dr. Mohammad Kazem Momeni, Dr. Nour Mohammad Bakhshani, Maliheh Metanat, Roghayeh Sheervalilou |
2020-10-08 |
| Efficacy and Safety of Molnupiravir (MK-4482) in Hospitalized Adult Participants With COVID-19 |
Coronavirus disease 19 infection |
molnupiravir alone |
RNA polymerase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Merck Sharp & Dohme Corp |
|
|
2020-10-19 |
2021-10-18 |
2020-003367-26, 4482-001, MK-4482-001, NCT04575584 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
0 |
12 Months |
1300 |
Medical Director |
2020-10-08 |
| The possible beneficial role of the regular use of potent mouthwash solutions in the treatment of COVID-19 |
Coronavirus disease 19 infection |
chlorhexidine gluconate plus hydrogen peroxide |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hamad Medical Corp |
|
Qatar |
2020-04-30 |
2020-11-20 |
ISRCTN10197987, MRC 05-106 |
Phase 2 Clinical |
No longer recruiting |
2 |
6 Months |
100 |
Dr Mukhtar |
2020-10-08 |
| New Educational Tool for FM |
Coronavirus disease 19 infection, Fibromyalgia, Pain |
PNE-explained alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Hospital Vall D'Hebron |
University of South Australia |
Spain |
2020-09-21 |
2021-10-10 |
NCT04571853, NEW EDUCATION TOOL |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
300 |
Elena Granell, Lorimer Moseley, PhD, Mayte Serrat, MSc, Sara Marsall, PhD |
2020-10-08 |
| DeCODe: Detection of COVID-19 Decompensation |
Coronavirus disease 19 infection |
PinpointIQ solution (physIQ, Inc.) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
PhysIQ Inc |
National Cancer Institute, National Institute of Biomedical Imaging and Bioengineering, University of Illinois |
US |
2020-10-05 |
2021-01-22 |
CTP-004, DeCODe, NCT04575532 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
400 |
Karen Larimer, PhD |
2020-10-08 |
| Remote Yoga Nidra for Anxiety and Sleep |
Anxiety disorder, Coronavirus disease 19 infection, Sleep disorder |
Yoga Nidra alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National College of Natural Medicine |
|
US |
2020-04-15 |
2020-09-14 |
NCT04571593, NUNM |
Phase Not Applicable |
Completed |
1 |
5 Months |
74 |
Erica M Sharpe, PhD |
2020-10-08 |
| Clinical Study Spartan COVID-19 V2 System |
Coronavirus disease 19 infection |
Spartan COVID-19 v2 System alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Spartan Bioscience Inc |
Beaufort |
US, Canada |
2020-10-31 |
2020-11-30 |
NCT04575168, VNV-00615 |
Phase Not Applicable |
Not yet recruiting |
2 |
1 Month |
100 |
|
2020-10-08 |
| Effectiveness of VIRTUAL FIBROWALK STUDY |
Coronavirus disease 19 infection, Fibromyalgia |
Treatment as Usual (TAU) alone, VIRTUAL FIBROWALK alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Hospital Vall D'Hebron |
|
Spain |
2020-09-21 |
2021-11-10 |
NCT04571528, PR(AG)249/2020 |
Phase Not Applicable |
Recruiting |
1 |
13 Months |
300 |
Elena Granell, Mayte Serrat, MSc, Sara Marsal, PhD |
2020-10-08 |
| RESPECT: A Research Platform to Screen Healthcare Workers |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The University Health Network |
|
Canada |
2020-04-16 |
2021-04-16 |
20-5289, NCT04574765, OZUHN-001, RESPECT |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
100000 |
Amit M Oza, MD, Amit Oza, MD |
2020-10-08 |
| A study to assess safety and efficacy of PTX-COVID19-B for coronavirus infection |
Coronavirus disease 19 infection |
PTX-COVID19-B alone |
COVID19 Spike glycoprotein modulator |
|
University of Toronto |
Providence Therapeutics Holdings Inc |
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-10-06 |
| Prevalence of COVID-19 Infection in a Cohort of Patients Infected by the HIV and Patients Taking PrEP |
Coronavirus disease 19 infection, HIV infection |
ELISA test alone, emtricitabine + tenofovir alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hôpital Européen Marseille |
|
France |
2020-10-31 |
2022-04-30 |
2020-A02018-31, NCT04575545 |
Phase Not Applicable |
Not yet recruiting |
1 |
18 Months |
600 |
Myriam BENNANI, Patrick PHILIBERT |
2020-10-07 |
| HOPE_BRAZIL: A Trial of Hydroxychloroquine Plus Azithromycin in High-Risk COVID-19 |
Coronavirus disease 19 infection |
Reuquinol plus azithromycin |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Latin American Cooperative Oncology Group |
Oncoclinicas |
Brazil |
2020-06-30 |
|
HOPE_BRAZIL, LACOG 0220, NCT04575558 |
Phase 2 Clinical |
Terminated |
7 |
|
|
|
2020-10-21 |
| I-RAMIC: IRAK4 Inhibition in Treatment of COVID-19 With ARDS |
Coronavirus disease 19 infection, Inflammatory disease, Respiratory distress syndrome |
PF-06650833 alone, standard of care treatment alone, PF-06650833 plus ritonavir |
Cytochrome P450 3A4 inhibitor, HIV protease inhibitor, HIV-1 protease inhibitor, IRAK-4 protein kinase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Yale University |
Pfizer Inc |
US |
2020-10-10 |
2021-03-31 |
2000028042, I-RAMIC, NCT04575610 |
Phase 2 Clinical |
Not yet recruiting |
1 |
5 Months |
68 |
Hyung Chun, MD, Kelly Borges, MS, BS |
2020-10-08 |
| Evaluation of the effect of nano-based inhalation solution to relieve shortness of breath in COVID-19 patients |
Coronavirus disease 19 infection, Dyspnea, Lung infection, Respiratory disease |
corticosteroid therapy alone, nebulizer mask alone, Variable regimens including colloidal silver nasal spray , dexamethasone , heparin , interferon beta-1a , interferon beta-1b , prednisolone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ahvaz University of Medical Sciences |
|
Iran |
2020-08-22 |
|
IR.AJUMS.REC.1399.345, IRCT20190226042851N1 |
Phase 3 Clinical |
No longer recruiting |
1 |
|
40 |
Fatemeh ahmadi, Hakim abiavy, Yousefi farid, mohamad badavi |
2020-10-07 |
| A trial to evaluate merimepodib monotherapy for the treatment of COVID-19 patients in the outpatient setting |
Coronavirus disease 19 infection |
merimepodib alone |
Inosine monophosphate dehydrogenase inhibitor |
|
Biosig Technologies Inc |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-10-06 |
| Efficacy and Safety of Molnupiravir (MK-4482) in Non-Hospitalized, Adult Participants With COVID-19 |
Coronavirus disease 19 infection |
molnupiravir alone |
RNA polymerase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Merck Sharp & Dohme Corp |
|
|
2020-10-19 |
2021-10-14 |
2020-003368-24, 4482-002, MK-4482-002, NCT04575597 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
0 |
11 Months |
1450 |
Medical Director |
2020-10-12 |
| A Study of RLS-0071 in Patients With Acute Lung Injury Due to COVID-19 Pneumonia in Early Respiratory Failure |
Acute lung injury, Coronavirus disease 19 infection, Hypoxia, Inflammatory disease, Respiratory failure, Viral pneumonia |
PIC1-01 alone |
Complement C1s subcomponent inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
ReAlta Life Sciences Inc |
|
US |
2020-10-31 |
2021-07-31 |
NCT04574869, RLS-0071-102 |
Phase 1 Clinical |
Not yet recruiting |
1 |
9 Months |
42 |
Efrain Garcia, MD, Kenji Cunnion, MD, MPH, Linda Dell, Naty Diaz, Rocio Navarro |
2020-10-12 |
| A new observational study finds patients in the hospital for COVID-19 have high levels of soluble urokinase receptor (suPAR) |
Coronavirus disease 19 infection |
|
|
|
University of Michigan |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
352 |
|
2020-10-07 |
| A global, phase II/III study to assess safety and efficacy of COVID-19 vaccine |
Coronavirus disease 19 infection |
SCB-2019 alone |
COVID19 Spike glycoprotein modulator |
|
Clover Biopharmaceuticals Inc |
Coalition for Epidemic Preparedness Innovations |
|
2020-12-31 |
|
|
Phase 2/Phase 3 Clinical |
Planned |
0 |
|
|
|
2020-10-07 |
| A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Safety, Tolerability, and Preliminary Efficacy of Intravenous Allogeneic Mesenchymal Stem Cells in Patients with Moderate to Severe Lung Injury due to COVID-19 |
Coronavirus disease 19 infection |
Allogeneic Mesenchymal Stem Cells, Stemedica Cell Technologies, Inc alone, standard treatment alone |
|
|
Stemedica Cell Technologies Inc |
|
|
|
|
|
Phase 2 Clinical |
Not yet recruiting |
0 |
|
40 |
|
2020-10-06 |
| MAVIPAN: My Life and the COVID-19 Pandemic |
Coronavirus disease 19 infection, Psychiatric disorder |
|
|
Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universite Laval |
CISSS de Chaudiere-Appalaches, Center for Interdisciplinary Research in Rehabilitation and Social Integration, Cervo Brain Research Centre, Réseau Provincial de Recherche en Adaptation-Réadaptation, Réseau québécois de recherche sur le vieillissement |
Canada |
2020-04-29 |
2025-04-29 |
MAVIPAN, NCT04575571, TO BE ASSIGNED |
Phase Not Applicable |
Recruiting |
1 |
60 Months |
5000 |
Annie LeBlanc, PhD, Marie Baron, PhD |
2020-10-07 |
| Online multicomponent health intervention to support children with special education needs (SEN) and their families during COVID-19 pandemic |
Attention deficit hyperactivity disorder, Coronavirus disease 19 infection |
multi-component online health intervention alone |
|
Preschool Children (2-5 yrs), Children (6-12 yrs) |
Hong Kong Jockey Club |
|
China |
2020-11-02 |
2021-12-02 |
ChiCTR2000038827 |
Phase Not Applicable |
Not yet recruiting |
1 |
13 Months |
1500 |
Prof. Eric Lee Kam Pui, Yuk Fai Ryan Ho |
2020-10-07 |
| HARD-COVID19: Health care workers exposed to COVID-19 |
Coronavirus disease 19 infection |
EMDR therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital, Tours |
INSERM |
|
2020-10-15 |
2022-07-15 |
1-20-046 ID 48680, 2020-A01642-37, DR200160-HARD-COVID-19, HARD-COVID19, NCT04570202 |
Phase Not Applicable |
Not yet recruiting |
0 |
21 Months |
900 |
Wiebe de JONG, MSc, Wissam EL-HAGE, MD-PhD |
2020-10-08 |
| Covid19Reh: Cardiorespiratory Exercise & Chinese Medicine for Rehabilitation of Discharged Coronavirus Disease (COVID-19) Patients |
Coronavirus disease 19 infection, Pulmonary fibrosis |
cardiorespiratory exercise alone, modified Bai He Gu Jin Tang alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hong Kong Baptist University |
Chinese University of Hong Kong, Hong Kong Polytechnic University, The University of Hong Kong, University of California San Diego, University of South Wales, Yale University |
Hong Kong |
2020-10-01 |
2023-06-30 |
Covid19Reh, HKCOVID19REHAB, NCT04572360 |
Phase Not Applicable |
Not yet recruiting |
1 |
33 Months |
172 |
Julien Baker, Ph.D, D.Sc, Linda Zhong, Linda Zhong, MD,PhD, Zhaoxiang Bian, Ph.D |
2020-10-19 |
| VPPIA: Virtual Parental Presence on Induction |
Anxiety disorder, Coronavirus disease 19 infection |
Use of Facetime with child and parents during induction alone |
|
Preschool Children (2-5 yrs), Children (6-12 yrs) |
Cincinnati Children's Hospital Medical Center |
Hospital for Sick Children |
Canada, US |
2020-10-31 |
2022-12-31 |
2020-0371, NCT04574219, VPPIA |
Phase Not Applicable |
Not yet recruiting |
2 |
26 Months |
184 |
Clyde Matava, MD, Fahad Alam, MD, Kennth Goldschneider, MD, Kristie Geisler, BS, CCRP, Monica Caldeira-Kulbakas, Sawita Kanavitoon, Vanessa Olbrecht, MD |
2020-10-08 |
| PRIME: Prematurity Risk Assessment Combined With Clinical Interventions for Improving Neonatal outcomes |
Coronavirus disease 19 infection, Premature labor |
Multimodal intervention strategy alone |
|
Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
High Risk Pregnancy Center, Sera Prognostics Inc |
|
US |
2020-10-28 |
2025-06-30 |
1760 KITCHEN, NCT04301518, PRIME, SP019, SP019 KITCHEN |
Phase Not Applicable |
Not yet recruiting |
1 |
56 Months |
6500 |
Ashley Magnavita, MPH, Brian Iriye, MD, Gregory Massey |
2020-10-21 |
| Self-Breathe RCT for Chronic Breathlessness |
Asthma, Bronchiectasis, Cancer, Cardiac failure, Chronic obstructive pulmonary disease, Coronavirus disease 19 infection, Cystic fibrosis, Dyspnea, Interstitial lung disease, Liver failure, Renal failure, Sickle cell anemia |
SELF-BREATHE alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kings College Hospital NHS Trust |
King's College London |
|
2020-12-03 |
2022-06-30 |
20/LO/1108, IRAS 285303, NCT04574050 |
Phase Not Applicable |
Not yet recruiting |
0 |
18 Months |
40 |
|
2020-10-08 |
| Access to Chiropractic Care During the COVID-19 Healthcare Emergency in Spain |
Coronavirus disease 19 infection |
Chiropractic care (more than one visit) alone, Chiropractic care (one visit) alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Real Escorial-Maria Cristina University Center |
The University of Birmingham, Universite du Quebec a Trois-Rivieres |
Spain |
2020-05-02 |
2020-05-27 |
CHIROCOVID19, NCT04573361 |
Phase Not Applicable |
Completed |
1 |
|
723 |
Arantxa Ortega de Mues, PhD |
2020-10-19 |
| The Delays Among Covid-19 Cases in Samarahan Division, Sarawak |
Coronavirus disease 19 infection |
|
|
|
|
|
Malaysia |
2020-10-01 |
2020-10-28 |
56468, NMRR-20-2122-56468 |
Phase Not Applicable |
Status not specified |
1 |
|
|
Dr. Mohd Fahmi Bin Ismail |
2020-10-08 |
| Predicting Favorable Outcomes in Hospitalized Covid-19 Patients |
Coronavirus disease 19 infection |
EPIC risk score display alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
NYU Langone Health |
|
US |
2020-05-15 |
2021-05-15 |
NCT04570488, PAU COVID19 RCT |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
1200 |
Ashley Bagheri, MS, Jonathan Austrian, MD |
2020-10-14 |
| Online Education Intervention to Reduce Ageism Among Undergraduate Students |
Aging, Coronavirus disease 19 infection |
Online educational intervention to reduce ageism alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Mississippi |
|
|
2020-09-28 |
2020-10-31 |
21X-046, NCT04570917 |
Phase Not Applicable |
Not yet recruiting |
0 |
1 Month |
121 |
Daniel Riche, Nadeeja Wijayatunga |
2020-10-07 |
| Mild Hypothermia for COVID-19 ARDS |
Coronavirus disease 19 infection, Respiratory distress syndrome |
Arctic Sun 5000 alone, hypothermia alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Northwell Health Inc |
|
US |
2020-05-18 |
2020-12-31 |
NCT04570462, PROTOCOL 5.18.2020 APPROVED |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
20 |
Efstathia A Mihelis, MBA, Pey-Jen Yu, Pey-Jen Yu, MD |
2020-10-07 |
| MICIn: Investigating the COVID-19 mucosal immunity of children in Indonesia |
Coronavirus disease 19 infection |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Diponegoro University |
|
Indonesia |
2020-05-01 |
2021-10-15 |
ISRCTN32891583, MICIN210920, MICIn |
Phase Not Applicable |
Not yet recruiting |
1 |
17 Months |
100 |
Mrs RizkeCiptaningtyas |
2020-10-08 |
| Safety and Efficacy of Trans-Sodium Crocetinate (TSC) in SARS-CoV-2 (COVID-19) Infected Subjects |
Coronavirus disease 19 infection, Hypoxia |
standard of care alone, trans sodium crocetinate (intravenous), Diffusion Pharmaceuticals alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Diffusion Pharmaceuticals LLC |
|
Romania |
2020-09-10 |
2021-12-14 |
100-303, NCT04573322 |
Phase 1/Phase 2 Clinical |
Recruiting |
1 |
15 Months |
224 |
Adrian Streinu Cercel, MD, Anna Grace, MA, BSN, Harry N Cook, RPh/MBA |
2020-10-07 |
| Assessment of the effect of nanocurcumin supplement in patients with COVID-19 |
Coronavirus disease 19 infection, Lower respiratory tract infection, Upper respiratory tract infection |
nanocurcumin (Exir Nano Sina Company) alone, routine treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Tehran University of Medical Sciences |
|
Iran |
2020-05-21 |
2020-12-20 |
IR.TUMS.VCR.REC.1399.28, IRCT20131125015536N13 |
Phase Not Applicable |
Recruiting |
2 |
7 Months |
48 |
Mohammad Javad Hossein Zadeh, Neda Alijani, Saied Reza Jamali Moghadam, Tehran University of Medical Sciences |
2020-10-07 |
| SeaCole: Evaluating a new model of rehabilitation for individuals recovering from COVID-19 |
Coronavirus disease 19 infection |
Rehabilitation Program alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Nuffield Health Bournemouth |
|
UK |
2020-04-06 |
2023-12-31 |
ISRCTN14707226, NHCRP001, SeaCole |
Phase Not Applicable |
Not yet recruiting |
1 |
44 Months |
500 |
Dr Benjamin Kelly |
2020-10-08 |
| KetoCOVID: Acute Effects of Oral Ketone Ester on Cardiac Function in Patients With COVID-19 |
Coronavirus disease 19 infection |
D-beta-hydroxybutyrate-(R)-1,3 butanediol monoester alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Steno Diabetes Center Odense |
|
Denmark |
2020-10-01 |
2022-01-01 |
H-20021500, KetoCOVID, NCT04573764 |
Phase Not Applicable |
Not yet recruiting |
1 |
15 Months |
12 |
Jens Christian Laursen, MD, Peter Rossing, MD, Tor Biering-Sørensen, MD |
2020-10-13 |
| Treatment With Anti-SARS-CoV-2 Immunoglobulin In Patients With COVID-19 |
Coronavirus disease 19 infection |
anti-SARS-CoV-2 equine immunoglobulin (F(ab')2) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Instituto D'Or de Pesquisa |
|
|
2020-12-01 |
2021-03-31 |
NCT04573855, PCL04/2020 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
0 |
4 Months |
41 |
|
2020-10-07 |
| T Cells Response to SARS COV2 Peptides |
Coronavirus disease 19 infection |
ImmunoBiopsy metabolic activity method test (Savicell Diagnostic Ltd) alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Savicell Diagnostic Ltd |
|
Israel |
2020-10-10 |
2021-10-10 |
NCT04573348, PBMC _COVID 19 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
400 |
Irena Shahar, BA, Shafrira Shai, PhD, Yochai Adir, Prof |
2020-10-19 |
| START: A Registry Study of COVID-19 Serological and Virological Testing to Accelerate Recovery and Transition |
Coronavirus disease 19 infection |
blood sampling alone, standard of care PCR test alone, standard of care clinical antibody test alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Kentucky |
|
US |
2020-05-15 |
2023-12-31 |
NCT04573634, PHARM-20-COVID19-START, START |
Phase Not Applicable |
Recruiting |
1 |
43 Months |
960 |
Derek Forster, MD, Jill Kolesar, PharmD, MS |
2020-10-07 |
| Mesenchymal Stem Cells for the Treatment of COVID-19 |
Coronavirus disease 19 infection |
mesenchymal stem cells (PrimePro) alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
|
|
US |
2020-04-24 |
2020-09-01 |
NCT04573270, PRO00043080 |
Phase 1 Clinical |
Completed |
1 |
4 Months |
40 |
Ernst R Von Schwarz, MD, PhD |
2020-10-07 |
| AEC COVID-19: National Study 'AEC COVID-19' |
Coronavirus disease 19 infection |
Surgical procedure alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospitales Universitarios Virgen del Rocío |
|
Spain |
2020-03-01 |
2020-09-30 |
AEC COVID-19, AEC-COVID, NCT04573868 |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
1000 |
Isaias Alarcón, MD PhD, Salvador Morales, Salvador Morales-Conde, Salvador Morales-Conde, MD PhD |
2020-10-06 |
| Coping with COVID Pandemic |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Bangladesh Health Professions Institute |
|
Bangladesh |
2020-10-10 |
|
CTRI/2020/10/028196 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
3000 |
Asma Islam, K M Amran Hossain, Professor Md Obaidul Haque |
2020-10-05 |
| An observational, post-registrational study to evaluate the safety and efficacy of Avifavir in the treatment of patients with COVID-19 infection |
Coronavirus disease 19 infection |
favipiravir alone |
RNA polymerase inhibitor |
|
ChemRar Pharma |
Russian Direct Investment Fund |
Russian Federation |
|
|
|
Phase 4 Clinical |
Status not specified |
1 |
|
940 |
|
2020-10-05 |
| Clinical profile of neonates with suspected or proven SARS-CoV-2 infection |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Newborn Infants (up to 5 months) |
Government Medical College and Hospital,Chandigarh |
|
India |
2020-10-12 |
|
CTRI/2020/10/028202 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
30 |
Deepak Chawla |
2020-10-06 |
| The role of Yogic breathing techniques in progression and recovery from COVID-19 |
Coronavirus disease 19 infection |
Yoga alone, longer duration breathing technique (LDBT) alone, short duration breathing technique (SDBT) alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Ministry of Ayush |
|
India |
2020-10-08 |
|
CTRI/2020/10/028195 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
72 |
Dr Akshay Anand |
2020-10-06 |
| The application of ultrasound-guided superior laryngeal nerve block used for alleviation of agitation after endotracheal intubation |
Agitation, Coronavirus disease 19 infection, Delirium, Viral pneumonia |
B-guided superior laryngeal nerve block alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Shengjing Hospital of China Medical University, The First Affiliated Hospital of Wenzhou Medical University |
|
China |
2020-10-01 |
2021-06-30 |
ChiCTR2000038690 |
Phase 2 Clinical |
Not yet recruiting |
2 |
9 Months |
90 |
Jiehao Sun |
2020-10-06 |
| A survey to assess the effectiveness of Arsenicum Album 30C as a Prophylactic medicine against COVID-19 infection |
Coronavirus disease 19 infection |
Arsenicum Album 30C alone |
|
Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Institute of Homoeopathy |
|
India |
2020-10-04 |
|
CTRI/2020/10/028192 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
15000 |
Dr Raja manoharan, Dr Selvan |
2020-10-06 |
| A study to examine the impact of chronic rhinosinusitis (CRS) on COVID-19 |
Coronavirus disease 19 infection, Sinusitis |
|
|
|
American Academy of Allergy Asthma and Immunology |
|
China |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
1172 |
|
2020-10-05 |
| Effect of fluvoxamine on cytokine in COVID-19 patients |
Coronavirus disease 19 infection |
fluvoxamine (Abidi and Sobhan Pharmaceutical companies) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shaheed Beheshti Medical University |
|
Iran |
2020-07-22 |
|
IR.SBMU.NRITLD.REC.1399.177, IRCT20131115015405N4 |
Phase 2/Phase 3 Clinical |
No longer recruiting |
1 |
|
40 |
Mitra Safa |
2020-10-06 |
| Effect of Online Psycho-educational Interventions on Psychological Health of Patients with COVID-19 |
Acute stress disorder, Coronavirus disease 19 infection |
cognitive–behavioural techniques alone, mindfulness-based stress reduction techniques alone, multimedia psychoeducational content delivery though whatsApp alone, positive psychotherapy exercise alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shiraz University of Medical Sciences |
|
Iran |
2020-03-10 |
2020-05-14 |
IR.SUMS.REC.1399.011, IRCT20201001048893N1 |
Phase Not Applicable |
Completed |
2 |
2 Months |
50 |
Abbas Rezaeianzadeh, Maryam Shaygan, Zahra Yazdani |
2020-10-06 |
| Diabetes Outcomes in COVID-19 Pandemic |
Coronavirus disease 19 infection, Insulin dependent diabetes, Non-insulin dependent diabetes |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
SERVICES INSTITUTE OF MEDICAL SCIENCES |
|
Pakistan |
2020-06-01 |
2020-07-30 |
16102019, NCT04573335 |
Phase Not Applicable |
Completed |
1 |
1 Month |
1282 |
Saira Burney, MB, FRCP (Edin) |
2020-10-06 |
| Natural History of Post-Coronavirus Disease 19 Convalescence at the National Institutes of Health |
Chronic fatigue syndrome, Coronavirus disease 19 infection |
deep phenotyping alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Institute of Neurological Disorders and Stroke |
National Institutes of Health Clinical Center |
US |
2020-10-28 |
2024-12-31 |
000089-N, 10000089, NCT04573062 |
Phase Not Applicable |
Recruiting |
1 |
50 Months |
1000 |
Angelique Gavin, Avindra Nath, M.D. |
2020-10-24 |
| Metabolic Cofactor Supplementation and Hydroxychloroquine Combination in Covid-19 Patients |
Coronavirus disease 19 infection |
hydroxychloroquine plus serine + L-carnitine tartrate + N-acetylcysteine + nicotinamide riboside |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Scandibio Therapeutics AB |
Alanya Alaaddin Keykubat University, Alkü Alanya Education and Research Hospital, Bakirkoy Dr. Sadi Konuk Research and Training Hospital, Bağcılar Training & Research Hospital, Canakkale Onsekiz Mart University, Dr.Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi, Istanbul Bakirkoy Maternity and Children Diseases Hospital, Istanbul Medipol University Hospital, Monitor CRO, Ümraniye Training & Research Hospital |
Turkey |
2020-09-21 |
2021-03-31 |
COVID-19-MCS, NCT04573153 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
6 Months |
400 |
Assoc. Prof. Levent DOĞANAY, MD |
2020-10-19 |
| Intervention to promote exercise behavior among older adults under the epidemic of COVID-19 |
Coronavirus disease 19 infection |
exercise alone |
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kobe University |
|
Japan |
2020-09-29 |
|
UMIN000041990 |
Phase Not Applicable |
No longer recruiting |
1 |
|
300 |
Kazuhiro Harada |
2020-10-19 |
| A single-site, single-arm, open, Phase I Study to Evaluate the Safety, tolerability and pharmacokinetic of CD24-Fc in healthy adults |
Coronavirus disease 19 infection |
CD24-IgFc alone |
Signal transducer CD24 modulator |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Beijing Ditan Hospital Capital Medical Universty |
|
China |
2020-11-05 |
2021-08-05 |
ChiCTR2000038672 |
Phase 1 Clinical |
Not yet recruiting |
1 |
9 Months |
12 |
Longpin Yin, xianfeng Fang |
2020-10-08 |
| Effects of pulmonary rehabilitation in patients with COVID-19 |
Anxiety disorder, Coronavirus disease 19 infection, Depression, Dyspnea |
patient health information session alone, psychosocial support alone, pulmonary training rehabilitation alone, respiratory physiotherapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Klinik Bad Reichenhall |
Hochschule fur Gesundheit, Bochum, Ludwig-Maximilians University of Munich |
Germany |
2020-04-28 |
|
20-326, DRKS00023180 |
Phase Not Applicable |
Recruiting |
1 |
|
100 |
Konrad Schultz |
2020-10-07 |
| A clinical trial to focus on patients discharged after hospitalization for moderate to severe COVID-19 disease |
Coronavirus disease 19 infection |
|
|
|
National Institutes of Health |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-10-05 |
| A clinical trial to investigate whether anticoagulants or antithrombotic therapy can reduce life-threatening cardiovascular or pulmonary complications in newly diagnosed COVID-19 patients who do not require hospital admission |
Cardiovascular disease, Coronavirus disease 19 infection, Lung disease |
apixaban alone, aspirin alone |
Factor Xa antagonist |
|
National Institutes of Health |
|
|
|
|
|
Phase Not Applicable |
Recruiting |
0 |
|
|
|
2020-10-05 |
| A clinical trial to investigate the safety and effectiveness heparin to prevent clotting events and improve outcomes in hospitalized COVID-19 patients |
Coronavirus disease 19 infection |
heparin alone |
|
|
National Institutes of Health |
|
|
|
|
|
Phase Not Applicable |
Recruiting |
0 |
|
|
|
2020-10-08 |
| PROVID-CAPNETZ: Clinical, molecular and functional biomarkers for Prognosis, pathomechanisms and treatment strategies of COVID-19 (PROVID) |
Coronavirus disease 19 infection, Lung infection, Respiratory distress syndrome, Viral pneumonia |
biological sampling alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hannover Medical School |
Charite Universitaetsmedizin Berlin, Deutsche Forschungsgemeinschaft (DFG), German Federal Ministry of Education and Research, University of Leipzig |
Germany |
2020-10-15 |
|
DRKS00022871, Nr. 301-2008, PROVID-CAPNETZ |
Phase Not Applicable |
Not yet recruiting |
15 |
|
400 |
Grit Barten-Neiner |
2020-10-07 |
| Efficacy and safety of chlorpromazine in the treatment of COVID-19 patients |
Coronavirus disease 19 infection |
atazanavir + ritonavir (Razavi Pharmaceutical Institute) plus chlorpromazine (Tehran Shimi Company) |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Mazandaran University of Medical Sciences |
|
Iran |
2020-10-31 |
|
IR.MAZUMS.REC.1399.617, IRCT20200913048708N1 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
60 |
Dr Majid saeedi, Ebrahim Salehifar, Roya Ghasemian |
2020-10-06 |
| UVA Light Device to Treat COVID-19 |
Coronavirus disease 19 infection |
UV light therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cedars-Sinai Medical Center |
Aytu BioScience Inc |
US |
2020-10-31 |
2020-12-31 |
883, NCT04572399 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
5 |
Cedars-Sinai, George Chaux, MD, Melissa Hampton |
2020-10-09 |
| Low Dose Lung Radiotherapy to Treat COVID-19 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
external beam irradiation (0.5 Gy) alone |
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Lancashire Teaching Hospitals NHS Trust |
National Institute for Health Research (NIHR) |
UK |
2020-10-31 |
2021-04-30 |
285167, NCT04572412 |
Phase 1 Clinical |
Not yet recruiting |
1 |
6 Months |
13 |
Aashish Vyas, Dennis Hadjiyiannakis, Research Access |
2020-10-06 |
| COVIDTrach: A Cohort Study of Mechanically Ventilated COVID-19 Patients Undergoing Tracheostomy |
Coronavirus disease 19 infection |
tracheostomy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University College London |
|
UK |
2020-08-01 |
2021-08-01 |
COVIDTrach, NCT04572438, Z6364106/0000/00/00 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
2500 |
Nick JI Hamilton, MBChB PhD, Nick JI Hamilton, MBcHB PhD |
2020-10-07 |
| A case study on verapamil as treatment for refractory status epilepticus secondary to PRES syndrome on a SARS-Cov-2 infected patient |
Brain disease, Coronavirus disease 19 infection, Status epilepticus |
ceftriaxone alone, dexamethasone alone, enoxaparin sodium alone, hydroxichloroquine alone, lacosamide alone, levetiracetam alone, lopinavir + ritonavir alone, valproate alone, verapamil alone |
Calcium channel inhibitor, Dihydropyrimidinase related protein 2 modulator, HIV protease inhibitor, Low molecular weight heparin, Sodium channel modulator |
|
Hospital Universitario Severo Ochoa |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
1 |
|
2020-10-07 |
| FloR COVID-19: Pilot, Randomized, Controlled Trial: Fluoxetine to Reduce Hospitalization From COVID-19 Infection |
Coronavirus disease 19 infection |
fluoxetine hydrochloride alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Milton S. Hershey Medical Center |
|
US |
2020-09-30 |
2021-10-31 |
00015598, FloR COVID-19, NCT04570449 |
Phase 0 Clinical |
Not yet recruiting |
1 |
13 Months |
40 |
Erika Saunders, MD |
2020-10-06 |
| PHYTO CoV: Evaluation of phytopharmaceuticals to improve the prognosis of Covid-19 disease in Togo |
Coronavirus disease 19 infection |
Biocire alone, Immunitum alone, Immutop alone, Secure alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Lomé |
|
Togo |
2020-10-15 |
2021-04-30 |
PACTR202009483194545, PHYTO CoV |
Phase Not Applicable |
Not yet recruiting |
3 |
6 Months |
250 |
ADJOH Seraphin, DAGNRA Claver, EKOUEVI Didier Koumavi, Ihou WATEBA Mageste, KOKOU Kouami, SALOU Mounerou |
2020-10-17 |
| Dose Ranging Trial to Assess Safety and Immunogenicity of V-590 (COVID-19 Vaccine) in Healthy Adults |
Coronavirus disease 19 infection |
V-590 alone |
COVID19 Spike glycoprotein modulator |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
International AIDS Vaccine Initiative, Merck Sharp & Dohme Corp |
Merck & Co Inc |
|
2020-10-22 |
2021-12-03 |
NCT04569786, V590-001 |
Phase 1 Clinical |
Not yet recruiting |
0 |
13 Months |
252 |
Medical Director |
2020-10-09 |
| COntinuation Versus Interruption of Immunomodulating Drugs in case of an Infectious disease in IMID patients (COVID I2 study), with special attention for COVID 19: a pragmatic, explorative randomized controlled trial |
Coronavirus disease 19 infection, Crohns disease, Inflammatory bowel disease, Psoriasis, Psoriatic arthritis, Rheumatoid arthritis, Spondylarthritis, Ulcerative colitis |
continued IA alone, standard of care alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sint Maartenskliniek |
|
Netherlands |
2020-10-01 |
2022-10-01 |
NL73479.091.20, NL8922 |
Phase Not Applicable |
Planned |
1 |
24 Months |
2200 |
Merel Opdam |
2020-10-08 |
| DIEGO: A diet for the treatment of gout |
Coronavirus disease 19 infection, Gout |
usual care alone, whole food plant based diet counselling alone |
|
|
Reade Center for Rehabilitation and Rheumatology |
|
Netherlands |
2020-09-15 |
2022-03-31 |
2020.405 - NL74142.029.20, DIEGO, NL8903 |
Phase Not Applicable |
Recruiting |
1 |
18 Months |
30 |
Wendy Walrabenstein |
2020-10-09 |
| A Study Looking at the Effectiveness, Immune Response and Safety of a COVID-19 Vaccine in Adults in the United Kingdom |
Coronavirus disease 19 infection |
Variable regimens including Matrix M , NVX-CoV2373 , seasonal influenza vaccine (quadrivalent, VLP), Novavax |
COVID19 Spike glycoprotein modulator |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Novavax Inc |
UK Government |
UK |
2020-09-28 |
2022-01-14 |
2019nCoV-302, 2020-004123-16, NCT04583995 |
Phase 3 Clinical |
Recruiting |
18 |
15 Months |
9000 |
Anna Heinen, CRF Team, Dr. Jane Minton, Eilidh Wright, Lakshmi Kumar, Nargis Hemat, Or go to www.bepartof.bradfordresearch.nhs.uk, Paul T Heath, MB BS FRACP FRCPCH, Paula Coventry, Prof. Jeremy Turner, Research Team, Roy Soiza, Seth Toback, MD, Sonia Serrano or Karen Bisnauthsing, St. Helier Site Team, Study Team, Trial Study Coordinator, www.bfwh.nhs.uk |
2020-10-15 |
| BCG-PRIME: Bacillu Calmette Geurin vaccination to prevent serious respiratory tract infection and covid-19 in vulnerable elderly - and apative randomized controlled trial |
Coronavirus disease 19 infection, Respiratory tract infection |
BCG vaccine alone |
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universitair Medisch Centrum Utrecht |
The Netherlands Organisation for Health Research and Development |
Netherlands |
2020-08-27 |
|
2020-003470-47, 74730.041.20, BCG-PRIME, CoV-2_DDI |
Phase 4 Clinical |
Not yet recruiting |
1 |
|
5200 |
|
2020-10-07 |
| A Pilot study platform to investigate the pharmacodynamics on QT‐prolongation and pharmacokinetics after multiple dose administration of potential combination treatments for COVID-19 in healthy volunteers |
Coronavirus disease 19 infection |
lopinavir + ritonavir plus ribavirin |
HIV protease inhibitor |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Medical University of Vienna |
|
Austria |
2020-09-14 |
|
2020-002314-40, CoV-2_DDI |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
16 |
|
2020-10-05 |
| A randomized, double-blind, placebo-controlled, adaptive-design study to assess the safety and efficacy of daily 200 mg fluvoxamine as add-on therapy to standard of care in moderate severity COVID-19 patients |
Coronavirus disease 19 infection |
fluvoxamine alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Sigmadrugs Kft |
|
Hungary |
2020-09-17 |
|
2020-002299-11, SD-COVID19-01 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
100 |
|
2020-10-08 |
| Study on Traditional Chinese Medicine Intervention Program for the Sequela of novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Jiexingjunzi granule alone, Qibei Fuzheng granule alone |
|
|
Beijing University of Chinese Medicine |
Beijing institute of Traditional Chinese Medicine |
China |
2020-08-01 |
2021-08-01 |
ChiCTR2000038740 |
Phase 0 Clinical |
Not yet recruiting |
1 |
12 Months |
200 |
Chengxiang Wang, Shan Zhang |
2020-10-07 |
| Analysis on the Distribution of TCM Syndromes in convalescent novel coronavirus pneumonia (COVID-19) patients |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
Beijing University of Chinese Medicine |
Beijing institute of Traditional Chinese Medicine |
China |
2020-08-01 |
|
ChiCTR2000038739, ChiMCTR2000003991 |
Phase 0 Clinical |
Not yet recruiting |
1 |
|
800 |
Chengxiang Wang, Shan Zhang |
2020-10-06 |
| Angiotensin (1-7) for the Treatment of COVID-19 in Hospitalized Patients |
Coronavirus disease 19 infection |
angiotensin (1-7) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Stanford University |
|
US |
2020-11-30 |
2021-05-31 |
58189, NCT04570501 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
6 Months |
160 |
Kevin V Grimes, MD |
2020-10-07 |
| An observational, single-center study to determine if early treatment of patients with COVID-19 pneumonia with tocilizumab and/or steroids was associated with better outcome |
Coronavirus disease 19 infection, Pneumonia |
methylprednisolone alone, tocilizumab alone, methylprednisolone plus tocilizumab |
|
|
Universita Degli Studi di Genova |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
196 |
|
2020-10-04 |
| An experimental study to find out the impact of post COVID physiotherapy and rehabilitation in Bangladesh |
Coronavirus disease 19 infection |
physiotherapy alone, rehabilitation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
|
Bangladesh Physiotherapy Association |
Bangladesh |
2020-10-07 |
|
CTRI/2020/10/028179 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
300 |
KM Amran Hossain, Mohammad Anwar Hossain |
2020-10-17 |
| A cross sectional study to identify the symptoms that are presenting by COVID-19 suffering people in Bangladesh |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
|
|
Bangladesh |
2020-10-05 |
|
CTRI/2020/09/028165 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1000 |
KM Amran Hossain, Mohammad Anwar Hossain |
2020-10-07 |
| Pediatric COVID-19 Antibody Study |
Coronavirus disease 19 infection |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) |
Yokohama City University |
Japan Agency for Medical Research and Development |
Japan |
2020-10-12 |
|
UMIN000041769 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
50 |
Kenichi Nishimura, Takeharu Yamanaka |
2020-10-04 |
| A clinical trial to know the efficacy of Homoeopathic medicine as an adjuvant therapy to Standard treatment in COVID-19 patients |
Coronavirus disease 19 infection |
homoeopathic intervention alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Institute of Homoeopathy |
ESI Hospital Ayanavaram |
India |
2021-10-04 |
|
CTRI/2020/09/028164 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
50 |
Dr Nithiyaselvi, Dr Raja manoharan |
2020-10-17 |