Last updated: Oct 30, 2020 - 02:00 GMT

Title Indication Intervention Actions PatientSelection Sponsor Collaborator Country StartDate EndDate Identifiers Phase Recruitment Status Sites Trial Duration Enrollment Count Contacts LastChanged
Ampligen in Chronic Fatigue Syndrome Chronic fatigue syndrome, Coronavirus disease 19 infection rintatolimod alone 2,5-Oligoadenylate synthetase stimulator, Interferon type I receptor agonist, Ribonuclease stimulator, TLR-3 agonist Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) AIM ImmunoTech Inc US AMP 511, NCT00215813 Phase 3 Clinical Recruiting 2 Ann Marie Coverly, Charles Lapp, MD, Charles W. Lapp, M.D., Daniel Peterson, M.D., Daniel Peterson, MD, Diane Young 2020-10-27
PSY HCW Kel: The Psychological Impacts of Covid-19 Pandemic and Its Associated Socio-demographic Characteristics Among Government Health Care Workers in Kelantan, Malaysia Coronavirus disease 19 infection, Psychiatric disorder Healthy volunteers accepted Jabatan Kesihatan Negeri Kelantan Malaysia 2020-11-01 2021-02-01 56611, NMRR-20-2306-56611, PSY HCW Kel Phase Not Applicable Status not specified 0 3 Months Dr Noor Hashimah binti abdullah, Dr Tiong Wen Ning 2020-10-29
Morbidity Post COVID-19 - Investigation and call to action Coronavirus disease 19 infection Spirometry alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Griffith University, Royal Brisbane & Women's Hospital Royal Brisbane & Womens Hospital Research Foundation Australia 2020-11-02 2021-07-30 ACTRN12620001114932p Phase Not Applicable Not yet recruiting 0 8 Months 200 Dr Jennifer Paratz 2020-10-29
SOBI: Anakinra, COVID-19, Cytokine Storm Coronavirus disease 19 infection, Respiratory failure, Systemic inflammatory response syndrome, Viral pneumonia anakinra alone Type I IL-1 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Weill Medical College of Cornell University Swedish Orphan Biovitrum AB US 2020-11-30 2022-02-28 20-07022396, NCT04603742, SOBI Phase 2 Clinical Not yet recruiting 0 15 Months 100 Iris Y Navarro-Millan, MD, MSPH 2020-10-29
Best larnyngoscopes for tracheal intubation in covid patient with intubation box Coronavirus disease 19 infection CMAC video laryngoscope alone Young Adults (18-44 yrs) All India Institute of Medical Sciences India 2020-11-04 CTRI/2020/10/028637 Phase 3 Clinical Not yet recruiting 0 100 Dr Balbir Kumar 2020-10-29
Covid-19 infection during pregnancy and its effect on the mother and baby Coronavirus disease 19 infection Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Christian Medical College and Hospital India 2020-11-01 CTRI/2020/10/028636 Phase Not Applicable Not yet recruiting 0 100 Kavita Mandrelle 2020-10-29
Efficacy of Mouthwash in Reducing Salivary Carriage of COVID-19 Coronavirus disease 19 infection Betadine mouthwash alone, Peridex alone, RT-PCR alone, hydrogen peroxide alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ohio State University US 2020-10-01 2020-11-30 2020H0346, NCT04603794 Phase 4 Clinical Recruiting 0 2 Months 60 David Hall, Associate Professor, David L Hall, DDS, Purnima Kumar, PhD,DDS 2020-10-29
Use of Virunil an ayurvedic medicie as a supportive treatment in management of COVID-19 Coronavirus disease 19 infection Virunil alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) NRI Medical College India 2020-11-02 CTRI/2020/10/028635 Phase 2/Phase 3 Clinical Not yet recruiting 0 150 Dr K V S Kumar Chowdary, Dr Kuricheti S S Siva Krishna, Dr V Siva Prabodh 2020-10-29
Comparison of Efficacy of Dexamethasone and Methylprednisolone in Moderate-to-Severe COVID-19 Disease Coronavirus disease 19 infection Decadron alone, methylprednisolone (Pfizer) alone, Variable regimens including Decadron , convalescent plasma , methylprednisolone (Pfizer) , oxygen , tocilizumab Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Fatima Memorial Hospital Pakistan 2020-05-30 2020-07-01 FMH-06-2020-IRB-763-M, NCT04603729 Phase 3 Clinical Completed 0 1 Month 100 Arzinda F Syeda, MBBS, FCPS, Khurshid A Khan, MBBS, FACM 2020-10-29
Impact of high flow oxygen therapy on outcomes of COVID-19 patients Coronavirus disease 19 infection, Hypoxia, Respiratory failure high flow nasal oxygen therapy alone, oxygen alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rajendra Institute of Medical Sciences India 2020-11-02 CTRI/2020/10/028634 Phase Not Applicable Not yet recruiting 0 100 Dr Mohd Saif Khan 2020-10-29
Long-COVID19: Pilot Study Into LDN and NAD+ for Treatment of Patients With Post-COVID-19 Syndrome Coronavirus disease 19 infection IontoPatch alone, naltrexone plus nicotinamide adenine dinucleotide (NAD+) Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) AgelessRx US 2020-11-30 2021-06-30 ALRX004, Long-COVID19, NCT04604704 Phase 2 Clinical Not yet recruiting 0 7 Months 60 Sajad Zalzala, MD 2020-10-29
CONFINeo: Lockdown Impact on Spontaneous Premature Birth in a Level III NICU Coronavirus disease 19 infection, Premature labor Newborn Infants (up to 5 months) Central Hospital, Nancy, France France 2020-11-30 2021-05-31 2020PI168, CONFINeo, NCT04605172 Phase Not Applicable Not yet recruiting 0 6 Months 1000 Jean Michel Hascoet, Jean-Michel HASCOET 2020-10-29
Pilot Study Into the Use of Metformin and LDN for Patients With COVID-19 Coronavirus disease 19 infection metformin hydrochloride plus naltrexone AMP activated protein kinase stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) AgelessRx US 2020-11-30 2021-05-31 ALRX003, NCT04604678 Phase 2 Clinical Not yet recruiting 1 6 Months 80 Sajad Zalzala, MD 2020-10-29
Post-COVID-19 Epidemic Depression Assessment in Adults in South Punjab Pakistan Coronavirus disease 19 infection, Depression Islamia University of Bahawalpur Pakistan 2020-11-01 2020-11-15 NCT04604080, U1111-1260-1614 Phase Not Applicable Not yet recruiting 1 384 Jafir Shirazi, PhD 2020-10-29
ICUcovid: Perceived Stress Among ICU Medical Staff During COVID-19 Crisis Acute stress disorder, Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Liege Belgium 2019-06-26 2020-09-01 ICUcovid, NCT04604769, STRESSICUCOVID Phase Not Applicable Completed 1 14 Months 60 Anne-Sophie Nyssen, Audrey Vanhaudenhuyse 2020-10-29
TriACT: A Triple Combination Antiviral Coronavirus Therapy (TriACT) for COVID-19 Coronavirus disease 19 infection Variable regimens including hydroxychloroquine , nitazoxanide , ribavirin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rutgers University US 2020-10-31 2021-04-30 NCT04605588, PRO2020001862, TriACT Phase 2 Clinical Not yet recruiting 1 6 Months 70 Helaine Noveck, MPH, Jeffrey L Carson, MD 2020-10-29
Inspiratory Muscle Training in Patients With COVID-19 Coronavirus disease 19 infection aerobic exercise with cycle ergometer alone, breathing exercise alone, inspiratory muscle training alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sociedade Beneficente Israelita Brasileira Hospital Albert Einsten Brazil 2020-06-01 2020-10-23 34931220.1.0000.0071, COVID19_IMPACT, NCT04603963 Phase Not Applicable Terminated 1 4 Months 55 Elaine Cristina Pereira 2020-10-29
BEMICOP: Comparison of Two Different Doses of Bemiparin in COVID-19 Coronavirus disease 19 infection, Viral pneumonia bemiparin alone Factor Xa antagonist, Heparin agonist, Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Clinica Universidad de Navarra, University of Navarra Spain 2020-10-26 2021-07-31 BEMICOP, BEMICOP, NCT04604327 Phase 3 Clinical Recruiting 12 9 Months 164 David Filella, Elena Pina, Ernesto Botella, Jessica Abadía, Jorge Cuesta, Miguel Marcos, Ramon Lecumberri, MD, PhD, Ramon Lecumberri, Md, PhD, Ramón Lecumberri, MD, PhD, Rosa Vidal, Sonia Jiménez, Tania Galicia, Vanesa Sendín, Víctor Jiménez Yuste 2020-10-29
ACTION ON COVID-19: A Study to Test Whether BI-764198 Helps Lung Health of People Hospitalized With COVID-19 Adult respiratory distress syndrome, Coronavirus disease 19 infection BI-764198 alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Boehringer Ingelheim International GmbH 2020-10-30 2021-05-05 1434-0009, 2020-003211-96, ACTION ON COVID-19, NCT04604184 Phase 2 Clinical Not yet recruiting 0 6 Months 90 Boehringer Ingelheim 2020-10-29
SAFE PAC Survey: online survey among anaesthesiologists about method of assessing breathing tube before administering anaesthesia duirng Covid 19 pandemic Coronavirus disease 19 infection practice of airway examination survey alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Malankara Orthodox Syrian Church Medical College, Kolenchery India 2020-10-29 CTRI/2020/10/028696, SAFE PAC Survey Phase Not Applicable Not yet recruiting 1 392 DrGirijananadan D Menon 2020-10-29
Can Vitamin C reduces COVID-19 symptoms Coronavirus disease 19 infection vitamin C alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Cancer Institute, Jhajjar, AIIMS India 2020-11-05 CTRI/2020/10/028695 Phase 4 Clinical Not yet recruiting 1 100 DR BALBIR KUMAR 2020-10-29
A survey to know effect of Corona pandemic on medical postgraduate student’s mental stress and their attitude to choose anesthesiology as a career Acute stress disorder, Coronavirus disease 19 infection, Psychiatric disorder Survey alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute Of Medical Sciences, Rishikesh India 2020-11-30 CTRI/2020/10/028672 Phase Not Applicable Not yet recruiting 1 500 Ashutosh Kaushal 2020-10-29
Role of NGAL and Cystatin C in Prediction of Acute Kidney Injury Covid-19 Infection Coronavirus disease 19 infection, Renal injury, Respiratory distress syndrome, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ain Shams University Egypt 2020-10-31 2021-03-31 FMASU P82B/2020, NCT04603664 Phase Not Applicable Not yet recruiting 1 5 Months 88 Sanaa Farag Mahmoud Wasfy, eman wasfy, lecturer, sanaa wasfy, lecturer 2020-10-29
A study to evaluate Easy Check COVID-19 IgM/IgG POC Antibody Test Coronavirus disease 19 infection Easy Check COVID-19 IgM/IgG POC Antibody Test alone Truvian Sciences Inc US Phase Not Applicable Status not specified 1 2020-10-29
Study to Investigate the Benefits of Colchicine in Patients With COVID-19 Coronavirus disease 19 infection colchicine alone, standard care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Liaquat University of Medical & Health Sciences Universidad De Murcia Pakistan 2020-11-15 2021-06-14 LUMHS/REC/893, NCT04603690 Phase 3 Clinical Not yet recruiting 1 7 Months 102 Prof. Dr. Ikram Din Ujjan, MBBS, PhD, Prof. Dr. Saeed Khan, PhD 2020-10-29
PIOQ8: Effect of Pioglitazone on T2DM Patients With COVID-19 Coronavirus disease 19 infection, Non-insulin dependent diabetes anti-inflammatory therapy alone, antiviral therapy alone, pioglitazone alone, insulin glargine plus preprandial insulin Insulin ligand, Insulin receptor agonist, Insulin sensitizer, PPAR gamma agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dasman Diabetes Institute Ministry of Health in Kuwait, Texas Diabetes Institute, University of Kuwait Kuwait, US 2020-11-15 2021-06-29 NCT04604223, PIOQ8, RA HM-2020- 011 Phase 4 Clinical Not yet recruiting 3 7 Months 1506 Fahd Al-Mulla, PhD, Mohamed Abu-farha, Mohamed Abu-farha, PhD, Muhammed Abdul-Ghani, MD/PhD, Thamer Alessa, MD 2020-10-29
RINCOVID: Prevalence of COVID-19 in High Altitude: Insights From the Highest City of the World Coronavirus disease 19 infection COVID-PRESTO IgM/IgG test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre d’Expertise sur l’Altitude EXALT Peru 2020-10-26 2020-11-01 NCT04604249, RINCOVID, RINCOVID Phase Not Applicable Recruiting 1 200 Benoit Champigneulle, MD, Ivan Hancco, MD, Samuel Verges, PhD, Samuel Vergès, PhD 2020-10-29
COVIDEIT: Electrical Impedance Tomography: Collapse in Dependent Areas as a Predictor of Response to Prone Position Ventilation in COVID-19 Acute Respiratory Distress Syndrome Coronavirus disease 19 infection, Respiratory distress syndrome electrical impedance tomography alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre de Recherches du Service de Sante des Armees (CRSSA) France 2020-10-31 2022-04-30 2020-COVID19-16, COVIDEIT, NCT04603755 Phase Not Applicable Not yet recruiting 1 18 Months 15 Michael CARDINALE, MD 2020-10-29
The Phase 1b, randomized, double-blind, placebo-controlled study designed to assess the safety, tolerability, and pharmacokinetic/pharmacodynamic profile of BEMPEG in adult patients with mild COVID-19 Coronavirus disease 19 infection bempegaldesleukin alone CD122 agonist, IL-2 receptor agonist Nektar Therapeutics US Phase 1b Clinical Not yet recruiting 1 2020-10-29
Anxiety and Burnout in Anesthetists and Intensive Care Unit Nurses During COVID-19 Pandemic Anxiety disorder, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sisli Etfal Hospital Turkey 2020-05-01 2020-06-01 1577, NCT04604119 Phase Not Applicable Completed 1 1 Month 104 Sultan Acar Sevinç 2020-10-29
To Evaluate the Safety and Efficacy of CT-P59 in Patients With Mild to Moderate Syptoms of Severe Acute Respiratory Syndrome COVID-19 Coronavirus disease 19 infection CT-P59 alone COVID19 Spike glycoprotein inhibitor, Moesin modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Celltrion Healthcare Co Ltd South Korea 2020-09-25 2021-09-30 CT-P59 3.2, NCT04602000 Phase 2/Phase 3 Clinical Recruiting 1 12 Months 1020 ChangWoo Park, JiWoong Lim, Yeon-Sook Kim, MD, PhD 2020-10-28
COVID-19 in People With Primary Ciliary Dyskinesia Coronavirus disease 19 infection, Kartagener syndrome University of Bern EUROPEAN LUNG FOUNDATION, The Primary Ciliary Dyskinesia Foundation (PCDF), University Of Southampton Switzerland 2020-05-31 2025-05-31 COVID-PCD, NCT04602481 Phase Not Applicable Recruiting 2 60 Months 1000 Claudia E Kuehni, Prof., Eva SL Pedersen, Dr. 2020-10-28
ITHACA: Clinical trial of the investigational drug AMY-101 for the treatment of patients with severe COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome AMY-101 alone Complement C3 inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Amyndas Pharmaceuticals Greece 2020-10-23 2020-004408-32, AMY-101_ITHACA, ITHACA Phase 2 Clinical Recruiting 1 62 Panagiotis Skendros, MD, PhD 2020-10-28
CAMOVID: A multicenter, randomized trial to evaluate the efficacy and safety of camostat mesylate for the treatment of SARS-CoV-2 infection in ambulatory adult patients Coronavirus disease 19 infection camostat mesylate alone Serine protease inhibitor, Transmembrane serine protease 2 inhibitor, Trypsin inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-10-16 2020-003366-39, APHP200702, CAMOVID Phase 3 Clinical Recruiting 1 596 2020-10-29
Preserving Compassionate End of Life Care in the Pandemic Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) McMaster University Canadian Institutes of Health Research Canada 2020-03-16 2021-06-01 3WPC19, NCT04602520 Phase Not Applicable Recruiting 1 14 Months 135 Deborah Cook, Deborah Cook, MD MSc, Deborah J Cook, MD, France Clarke, RRT 2020-10-28
Ivermectin in Adults With Severe COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia ivermectin alone, standard management alone Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) CES University Colombia 2020-10-31 2021-02-28 ECA-COVID-CES, NCT04602507 Phase 2 Clinical Not yet recruiting 1 4 Months 100 Federico Rodriguez-Vega, MD, Internist, Federico Rodríguez-Vega, MD, Francisco L Ochoa-Jaramillo, MD, MSc, Nora Cardona.-Castro, MD, MSc, PhD, Veronica Posada-Velez, MD, Internist 2020-10-28
COVID-19EXO2: Safety and Efficiency of Method of Exosome Inhalation in COVID-19 Associated Pneumonia Coronavirus disease 19 infection, Viral pneumonia Mesenchymal Stem Cells Exosomes alone, standard therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Clinical Center of Cellular Technologies Samara Regional Clinical Hospital, Siberian State Medical University Russian Federation 2020-10-01 2021-12-30 COVID-19 EXO EXTENDED, COVID-19EXO2, NCT04602442 Phase 2 Clinical Recruiting 1 14 Months 90 Olga Tyumina 2020-10-28
A case report to assess real-world effectiveness data of a patient with sickle cell disease (SCD) treated with voxelotor in the setting of COVID‐19 Coronavirus disease 19 infection, Sickle cell anemia voxelotor alone Hemoglobin alpha subunit modulator Global Blood Therapeutics Inc Phase 4 Clinical Status not specified 0 2020-10-28
A phase III trial to evaluate MT-2766 in the treatment of subjects with COVID-19 Coronavirus disease 19 infection MT-2766 alone TLR-9 agonist Medicago Inc 2020-12-31 Phase 3 Clinical Planned 0 2020-10-29
The Evaluation of Nitric Oxide Generating Lozenges on Outcome in Newly Diagnosed COVID-19 Patient of African Americans Coronavirus disease 19 infection nitric oxide alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), African Ancestry Nitric Oxide Innovations LLC 2020-10-28 2021-07-31 IND150758 PILOT, NCT04601077 Phase 1/Phase 2 Clinical Not yet recruiting 0 9 Months 100 John C Somberg, MD 2020-10-28
A phase II trial to evaluate MT-2766 in the treatment of subjects with COVID-19 Coronavirus disease 19 infection MT-2766 alone TLR-9 agonist Medicago Inc 2020-11-01 Phase 2 Clinical Planned 0 2020-10-29
Survival Rates and Longterm Outcomes After COVID-19 Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia ICU treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Oslo University Hospital The Research Council of Norway Norway 2020-09-16 2022-09-30 135310, NCT04601090 Phase Not Applicable Recruiting 1 24 Months 250 Kristin Hofsø, PhD 2020-10-29
Functional Recovery of Hospitalized Patients With COVID-19: The COREG Extension Study Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) McMaster University Canada 2020-06-09 2021-09-30 COREG-EXTENSION_14567, NCT04602260 Phase Not Applicable Recruiting 1 15 Months 211 Hope Morrison, BA, Marla K Beauchamp, PhD 2020-10-29
A trial to evaluate AK-119 for the treatment of patients with mild to moderate COVID-19 Coronavirus disease 19 infection AK-119 alone CD73 antagonist Akeso Biopharma Inc US Phase Not Applicable Not yet recruiting 1 2020-10-28
CCP Cancer UK Companion Study Coronavirus disease 19 infection, Hematological neoplasm, Solid tumor The Clatterbridge Cancer Centre NHS Foundation Trust The University of Liverpool, University of Edinburgh, University of Oxford UK 2020-10-31 2022-10-31 C1147, NCT04603105 Phase Not Applicable Not yet recruiting 2 24 Months 9000 Carlo Palmieri, Lance Turtle, Michael Stacckpoole, Bsc, Molly Mcevoy 2020-10-29
Be-Home-Kids: Feasibility and Effectiveness of Home-behavioral Program for Adolescents With Migraine Coronavirus disease 19 infection, Migraine, Migraine without aura Mindfulness by Smartphone alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Fondazione IRCCS Istituto Neurologico Carlo Besta Italy 2020-09-15 2021-12-31 BE-HOME-KIDS, Be-Home-Kids, NCT04604977 Phase Not Applicable Recruiting 1 15 Months 25 Licia Grazzi, Licia Grazzi, MD, Renato Mantegazza, MD 2020-10-28
Clinic-based HPV and COVID-19 Vaccine Promoting Intervention for AfAm Adolescents in Alabama Coronavirus disease 19 infection, Papillomavirus infection COVID-19 Vaccine alone, HPV vaccine alone, HPV vaccine uptake behavior and reducing sentiments alone Healthy volunteers accepted, Adolescents (13-17 yrs) University of Alabama at Birmingham US 2021-01-01 2023-06-30 MISP #60590, NCT04604743 Phase Not Applicable Not yet recruiting 1 30 Months 4 Henna Budhwani 2020-10-29
DUO-EF-19: Point of Care Artificial Intelligence Tool for Heart Failure Diagnosis Cardiac failure, Coronavirus disease 19 infection artificial intelligence electrocardiogram alone, cardiac MRI alone, digital stethoscope alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Imperial College London 2021-02-01 2022-10-01 285417, DUO-EF-19, NCT04601415 Phase Not Applicable Not yet recruiting 0 20 Months 1500 2020-10-29
Online cognitive behavioral therapy for distress in people who lost a loved one during the corona pandemic: A randomized waitlist-controlled trial Acute stress disorder, Coronavirus disease 19 infection, Major depressive disorder, Post traumatic stress disorder online cognitive behavioral therapy alone, psychoeducation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universiteit Utrecht Netherlands 2020-07-01 2022-07-01 METC 20-446, NL8993 Phase Not Applicable Recruiting 1 24 Months 52 Lyanne Reitsma 2020-10-29
Nurse Leadership for Hospital Infection Control Coronavirus disease 19 infection, Infectious disease Intervention for COVID-19 preventive protocols alone, digital communication of written material alone, monthly online training and discussion alone Healthy volunteers accepted, Female Forman Christian College King Edward Medical University, Shalamar Medical and Dental College 2020-11-01 2021-03-01 NCT04603079, NURSELEADERSHIP Phase Not Applicable Not yet recruiting 0 4 Months 200 Sara Rizvi Jafree 2020-10-28
EN-COVID-19: Enduring Happiness and Continued Self-Enhancement (ENHANCE) for COVID-19 Anxiety disorder, Coronavirus disease 19 infection, Insomnia, Post traumatic stress disorder Enduring Happiness and Continued Self-Enhancement (ENHANCE) for COVID-19 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of British Columbia University of Utah, University of Virginia Canada 2020-10-14 2020-12-31 EN-COVID-19, NCT04602832, UNIVERSITY OF BRITISH COLUMBIA Phase Not Applicable Recruiting 1 2 Months 350 Lesley Lutes 2020-10-28
How Does Mindfulness Meditation Buffer the Negative Effects of Pain and Suffering in the COVID-19 World? (Healthy Sample) Coronavirus disease 19 infection, Pain Book listening alone, Mindfulness meditation alone, focussed-attention mindfulness meditation alone, sham mindfulness meditation alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Queensland University of California San Diego, University of Sydney Australia 2020-10-31 2021-03-31 2019000347-S4C, NCT04602312 Phase Not Applicable Not yet recruiting 1 5 Months 624 Jonathan Davies, MSc, Melissa Day, PhD 2020-10-29
How Does Mindfulness Meditation Buffer the Negative Effects of Pain and Suffering in the COVID-19 World? (Pain Sample) Coronavirus disease 19 infection, Pain Mindfulness meditation alone, focussed-attention mindfulness meditation alone, sham mindfulness meditation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Queensland University of California San Diego, University of Sydney Australia 2020-10-31 2021-03-31 2019000347-S4P, NCT04602286 Phase Not Applicable Not yet recruiting 1 5 Months 292 Jonathan Davies, MSc, Melissa Day, PhD 2020-10-29
Physiotherapist-led Exercise Within Cardiac Rehabilitation and Paroxysmal Atrial Fibrillation and COVID-19 Atrial fibrillation, Coronavirus disease 19 infection Physiotherapist-led exercise-based cardiac rehabilitation alone, Threshold Inspiratory Muscle Trainer (Respironics Inc) alone, central circulatory exercise alone, inspiratory muscle training alone, muscle exercise alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Vastra Gotaland Region Sweden 2021-01-31 2025-10-31 273293, NCT04600713 Phase Not Applicable Not yet recruiting 1 57 Months 180 Maria Borland, PhD RPT, Åsa Cider, PhD RPT 2020-10-29
STAMP: Strategies to Assist With Management of Pain Coronavirus disease 19 infection, Lower back pain Mindfulness Meditation alone, usual care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Wisconsin-Madison Patient Centered Outcome Research Institute US 2017-06-30 2021-07-15 2017-0353, A532007, NCT03115359, SMPH/FAMILY MED/FAMILY MED, STAMP Phase Not Applicable Recruiting 4 48 Months 766 Aleksandra E Zgierska, MD PhD, Amy Watson, BS, Bruce P Barrett, MD PhD, Cindy A Burzinski, MS, Eric Garland, PhD, Lauren Papianou, BS, Robert Edwards, PhD 2020-10-28
Adaptive, randomized, open, controlled study to assess the efficacy and safety of Nobazit, film-coated tablets, 250 mg (JSC Avexima, Russia) in the treatment of hospitalized patients with an infection caused by the SARS-CoV-2 virus (COVID-19) Coronavirus disease 19 infection enisamium iodide (Nobazit), Avexima alone Avexima OJSC Russian Federation 2020-10-27 2021-06-10 Nobazit-COVID-19-T-III-2020 Phase 3 Clinical Status not specified 13 7 Months 160 2020-10-29
Odorat-Covid: Evaluation of Two Methods of Olfactory Rehabilitation in Post-viral Loss of Smell: Classic and Intensive Coronavirus disease 19 infection, Dysomia, Olfactory nerve disorder smell the odors of the olfactory rehabilitation kit according to the intensive method alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Hospital, Nancy, France France 2020-07-01 2021-01-01 2020PI098, NCT04598763, Odorat-Covid Phase Not Applicable Recruiting 1 6 Months 80 Duc Trung NGUYEN, Duc Trung NGUYEN, MD, PhD, MPH, Julie Lecomte 2020-10-28
COVID-CARE: COVID-19, Chronic Adaptation and Response to Exercise Coronavirus disease 19 infection Aerobic Exercise Training alone, Education alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institutes of Health Clinical Center US 2020-11-02 2023-12-31 000102-CC, 10000102, COVID-CARE, NCT04595773 Phase 1/Phase 2 Clinical Not yet recruiting 1 37 Months 90 COVID-CARE Rehab Team, Leighton Chan, M.D. 2020-10-29
Detection of COVID-19 Using Breath Analysis - Validation Study (COVID-19) Coronavirus disease 19 infection Breath biopsy analysis alone, RT-PCR alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Israel 2020-11-12 2021-02-28 COV-2-SMC-2020, NCT04602949 Phase Not Applicable Not yet recruiting 1 3 Months 4000 Natalie Dror, PhD, Shai Efrati, Shai Efrati, MD 2020-10-29
ANTICOV EPI: Factors affecting transmission of SARS-CoV-2 in Households of SARS-CoV-2 patients in Sub-Saharan Africa Ancillary study of the ANTICOV Study: An open-label, multicenter, randomized, adaptive platform trial of the safety and efficacy of several therapies, including antiviral therapies, versus control in mild / moderate cases of COVID-19 Coronavirus disease 19 infection Hydroxychloroquine alone, lopinavir + ritonavir alone HIV protease inhibitor Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Barcelona Institute for Global Health, Bernhard-Nocht-Institute for Tropical Medicine, Drugs for Neglected Diseases Initiative, Ifakara Health Institute Mozambique, Equatorial Guinea, Ghana, Kenya 2020-11-02 2021-06-01 ANTICOV EPI, PACTR202010718451278 Phase Not Applicable Not yet recruiting 4 7 Months 2800 James Arkinstall, MarcAlain Widdowson, Nathalie Strub Wourgaft 2020-10-29
Early Detection of COVID-19 Using Breath Analysis Coronavirus disease 19 infection ReCIVA breath sampler alone, breath biopsy sampling alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Israel 2020-09-22 2020-12-30 COV-2-IDF, NCT04602884 Phase Not Applicable Suspended 1 3 Months 50 Natalie Dror, PhD 2020-10-29
VBW: Virtual Assisted Living Coronavirus disease 19 infection, Muscle weakness ambient assisted living system scanning alone, virtual assisted living preventive care alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) DAK Gesundheit, Innovationsausschuss beim Gemeinsamen BundesausschussProjektträger DLR, Philips Medical Systems Technologies Ltd Germany 2020-11-02 DRKS00023171, EA1/032/20, VBW Phase Not Applicable Not yet recruiting 1 207 Anne Gersitz, Johanna Nordheim 2020-10-28
Training Load Management in Three Professional Tennis Players During COVID-19 Lockdown: a Case Series Study Coronavirus disease 19 infection training load monitoring alone Healthy volunteers accepted, Male Kine Kinesiologia Deportiva y Funcional Argentina 2019-12-15 2021-01-15 NCT04602637, TLT01 Phase Not Applicable No longer recruiting 1 13 Months 3 Diego Mendez, PT 2020-10-29
Knowledge Attitude and Practice of Hand hygiene among Nursing Assistants and Trolley workers in a COVID-19 care units Coronavirus disease 19 infection questionnaire alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Government Medical College Kannur India 2020-11-05 CTRI/2020/10/028600 Phase Not Applicable Not yet recruiting 1 100 Dr Venugopalan A K 2020-10-29
CoPa: Handling and coping with the corona pandemic (Covid-19) and its physical and psychological effects Coronavirus disease 19 infection, Psychiatric disorder Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Lubeck Germany 2020-04-05 20-118, CoPa, DRKS00023393 Phase Not Applicable Recruiting 1 5000 Elke Peters 2020-10-27
Factors Associated with Covid-19 Infection in Kinta District, Perak: A Case-Control Study Coronavirus disease 19 infection Malaysia 2021-01-01 2021-02-28 56860, NMRR-20-2286-56860 Phase Not Applicable Not yet recruiting 1 2 Months Dr Asraf Ahmad bin Qamruddin 2020-10-27
Covid-19 and Major Organ Thromboembolism: Manifestations in Neurovascular and Cardiovascular Systems Cardiovascular disease, Cerebrovascular disease, Coronavirus disease 19 infection, Thromboembolism Hospital Kuala Lumpur Malaysia 2020-10-23 2020-10-31 56982, NMRR-20-2283-56982 Phase Not Applicable Status not specified 1 Dr Presaad Pillai A/L Perianen 2020-10-28
The evaluation of efficacy of favipiravir in patients with mild-to-moderate COVID-19 Coronavirus disease 19 infection favipiravir (Dr. Abidi Pharmaceutical Co) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dr.Abidi's Pharmaceutical Laboratories Iran 2020-10-31 IR.TUMS.IKHC.REC.1399.215, IRCT20201005048936N1 Phase 3 Clinical Not yet recruiting 3 126 Ali Rakei, Ayat Ahmadi, Mahboubeh Hajabdolbaghi, Mahshid Talebi Taher, Masoud Mardani 2020-10-29
COP20: Convalescent Plasma in the Treatment of Covid-19 Coronavirus disease 19 infection, Respiratory disease convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Skåne University Hospital Sweden 2020-04-25 2022-02-28 COP20, COVID CONVALESCENT PLASMA, NCT04600440 Phase 2 Clinical Recruiting 1 22 Months 100 Magnus Rasmussen, MD, Prof, Maria N Lundgren, MD, Mona Landin-Olsson, MD, Prof 2020-10-27
Early Detection of COVID-19 Using Breath Analysis - Feasibility Study Coronavirus disease 19 infection ReCIVA Breath Sampler alone, breath biopsy sampling alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Israel 2020-07-03 2021-01-30 COV-2-2020, NCT04602871 Phase Not Applicable Recruiting 2 6 Months 108 David Shitrit, MD, Natalie Dror, PhD, Victor Novac, MD 2020-10-28
Mechanically assisted Airway clearence COVID -19 Coronavirus disease 19 infection mechanically assisted airway clearance alone Hospital Sungai Buloh Malaysia 2020-11-02 2021-07-01 55173, NMRR-20-2280-55173 Phase Not Applicable Status not specified 1 8 Months DR AKMAL HAFIZAH ZAMLI, swarna lata krishnabahawan 2020-10-29
DISH19: Dietary supplements use among health-care workers during the COVID-19 pandemic in Malaysia: a cross-sectional study Coronavirus disease 19 infection Dietary supplements alone Seberang Jaya Hospital Malaysia 2020-12-01 2021-06-30 56853, DISH19, NMRR-20-2275-56853 Phase Not Applicable Status not specified 1 7 Months Dr Looi Irene, Lee Heoy Teng 2020-10-28
OCTA Study: Retinal Vascular Changes in SARS-CoV-2 Patients Coronavirus disease 19 infection optical coherence tomography angiography alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universita degli Studi di Napoli Federico II Italy 2020-09-20 2020-10-22 2020/03, NCT04601012 Phase Not Applicable Completed 1 1 Month 40 Gilda Cennamo 2020-10-29
HEPMAB: Clinical Efficacy of Heparin and Tocilizumab in Patients With Severe COVID-19 Infection: a Randomized Clinical Trial Coronavirus disease 19 infection Variable regimens including enoxaparin sodium , heparin , tocilizumab Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Sao Paulo Conselho Nacional de Desenvolvimento Cientifico e Tecnologico - CNPq Brazil 2020-10-20 2021-12-31 5057/20/086, HEPMAB, NCT04600141 Phase 3 Clinical Not yet recruiting 1 14 Months 308 Lucas TC Ribeiro, Ludhmila A Hajjar, MD, PhD 2020-10-27
COVID-19 Tests: Nasopharyngeal Swab versus Saliva Collected With Salivette Cortisol for Viral RNA Sampling for RT-qPCR Coronavirus disease 19 infection Kylt detection kit alone, Salivette alone, TaqPath COVID-19 CE-IVD RT-PCR kit alone, cobas SARS-CoV-2 PCR test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Boehringer Ingelheim International GmbH 2020-10-20 2020-11-13 0352-2150, NCT04599959 Phase Not Applicable Not yet recruiting 0 80 2020-10-28
ComICU: Communication in ICU During COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) NMC Specialty Hospital United Arab Emirates 2020-11-01 2020-12-31 COMICU, ComICU, NCT04602351 Phase Not Applicable Not yet recruiting 1 2 Months 200 Gunjan Chanchalani, MD FNB, Prashant Nasa, Prashant Nasa, MD EDICM 2020-10-29
Venous Thromboembolism in Patients with COVID-19 in Japan Study Coronavirus disease 19 infection, Thromboembolism Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kuwana East Medical Center Japan 2020-11-01 UMIN000042235 Phase Not Applicable Recruiting 1 200 Norikazu Yamada, Yugo Yamashita 2020-10-29
Long-term, Follow-up Findings of Inpatients for COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia Cardiopulmonary exercise testing alone, spirometry alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Turkey 2020-10-15 2021-03-01 2020.188.IRB1.056, NCT04599998 Phase Not Applicable Recruiting 1 4 Months 37 Benan Çağlayan, Prof Dr, Fatma Işıl Uzel, MD 2020-10-29
PRESECO: The Prevent Severe COVID-19 (PRESECO) Study Coronavirus disease 19 infection favipiravir alone RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Appili Therapeutics Inc US 2020-11-30 2021-10-31 ATI0220, NCT04600895, PRESECO Phase 3 Clinical Not yet recruiting 1 11 Months 826 2020-10-29
Co-CAT: Child anxiety treatment in the context of COVID-19 Anxiety disorder, Coronavirus disease 19 infection online psychological intervention (OSI) alone, therapist support alone Preschool Children (2-5 yrs), Children (6-12 yrs) University of Oxford United Kingdom Research & Innovation UK 2020-09-01 2021-08-31 Co-CAT, IRAS 288074, CPMS 46902, ISRCTN12890382 Phase Not Applicable Not yet recruiting 2 12 Months 560 Mrs Taylor 2020-10-27
The protective effect of powered air purifying respirators during chest compressions: A simulation study Coronavirus disease 19 infection Mask Fitting Tester ((SIBATA Scientific Technology Ltd) alone, powered air purifying respirator (PAPR) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Nagoya University Nakatani foundation Japan 2020-12-01 UMIN000042239 Phase Not Applicable Not yet recruiting 1 54 Yukari Goto 2020-10-29
An essential research study to advance the use of telehealth for rehabilitation in response to public health crises such as the COVID-19 pandemic Brain injury, Coronavirus disease 19 infection, Spinal cord injury, Stroke telehealth for rehabilitation alone Brooks Rehabilitation Clinical Research Center, Inc Madonna Rehabilitation Hospital, Mary Free Bed Rehabilitation Hospital US Phase Not Applicable Recruiting 3 Dr. Judith Burnfield, Dr. Raine Osborne, Jason Peoples, Kenneth Ngo, MD 2020-10-27
Assessment of SARS CoV-2 seroprevalence and clinical profiling of COVID Unsuspected patients attending Otorhinolaryngology Department at AIIMS Jodhpur Coronavirus disease 19 infection IgM and IgG antibody testing alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) AIIMS Jodhpur India 2020-11-02 CTRI/2020/10/028598 Phase Not Applicable Not yet recruiting 1 50 Dr Amit Goyal, Dr Nitika Goyal 2020-10-29
The Effects of Narrative Exposure Therapy on COVID-19 Patients with Post-Traumatic Stress Disorder: A Randomized Controlled Trial Coronavirus disease 19 infection, Post traumatic stress disorder narrative exposure therapy alone Xiangyang Central Hospital China 2020-02-28 ChiCTR2000039369 Phase 0 Clinical No longer recruiting 2 111 Fan Ying 2020-10-27
The clinical characteristics and the etiology of COVID-19 infected patients with myocardial damage Coronavirus disease 19 infection, Heart injury Tongji Hospital, Huazhong University of Science and Technology, Tongji Medical College China 2020-10-30 ChiCTR2000039364 Phase Not Applicable Not yet recruiting 1 200 Cheng Wang, FengZhu, ZhouMin 2020-10-28
An open-label, prospective study to evaluate RLF-100 in patients admitted to an intensive care unit (ICU) with critical COVID-19 and respiratory failure Coronavirus disease 19 infection, Respiratory failure aviptadil (inhaled, sarcoidosis/acute lung injury/acute respiratory distress syndrome associated COVID-19), Relief Therapeutics Holding alone Adrenergic receptor antagonist, VIP receptor agonist NeuroRx Inc, Relief Therapeutics Holding AG Phase 2 Clinical Status not specified 0 2020-10-26
A trial to evaluate PGX-YBG for the treatment of patients with COVID-19 Coronavirus disease 19 infection PGX-YBG alone Ceapro Inc Phase Not Applicable Planned 0 2020-10-26
EAT COVID: An investigator initiated, randomized, Phase II clinical trial evaluating its eftilagimod alpha (“efti” or “IMP321”) in hospitalized patients with COVID-19 Coronavirus disease 19 infection eftilagimod alfa alone, standard care alone HLA class II antigen stimulator Immutep Ltd University Hospital Pilsen Czech Republic EAT COVID Phase 2 Clinical Recruiting 1 110 Dr. Dalibor Sedlacek, Dr. Marek Nalos,, Martin Matejovic 2020-10-26
A phase Ib clinical study to assess ProTrans in the treatment of subjects with COVID-19 Coronavirus disease 19 infection ProTrans alone NextCell Pharma AB Karolinska Trial Alliance Sweden Phase 1b Clinical Planned 1 9 Doctor Tomasz Oldak, Professor Dominique Farge, Professor Edvard Smith, Professor Farge, Professor Josefin Sundh 2020-10-26
SARS-CoV-2 (COVID-19) Immune Surveillance Among a Population Based Sample of Adults in Florida Coronavirus disease 19 infection SARS-CoV-2 antibody analysis alone, Weck-cel swab collection alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) H Lee Moffitt Cancer Center and Research Institute Merck Sharp & Dohme Corp US 2020-10-09 2022-10-09 MCC-20635, NCT04596579 Phase Not Applicable Recruiting 2 24 Months 1200 Anna R Giuliano, PhD 2020-10-27
oXAKI-COV: Efficacy and Safety of a Highly Selective Semipermeable Membrane (AN69 oXiris) versus (Standard AN69) in COVID-19 Coronavirus disease 19 infection, Inflammatory disease, Renal injury AN69 oXiris alone, continuous renal replacement therapy alone, vasopressor therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Instituto Nacional de Ciencias Medicas y Nutricion Mexico 2020-10-02 2022-03-30 NCT04597034, NMM-3401-20-20-1, oXAKI-COV Phase Not Applicable Recruiting 1 17 Months 35 Mauricio Arvizu-Hernández, MD, Olynka Vega Vega, MD, Olynka Vega-Vega, MD, Ricardo Correa Rotter, MD, Ricardo Correa-Rotter, MD 2020-10-28
Vitamin D3 Supplementation to Prevent Respiratory Tract Infections Coronavirus disease 19 infection, Respiratory tract infection vitamin D, Cooper alone Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The Cooper Health System 2020-10-31 2021-11-30 20-455, NCT04596657 Phase Not Applicable Not yet recruiting 0 13 Months 2099 Noud van Helmond, MD 2020-10-27
Study to Evaluate Efficacy and Safety of 'Viracide' in the Management of Corona Virus Disease 2019 (COVID-19) Coronavirus disease 19 infection ViraCide alone, standard of care alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) India 2020-09-16 2021-01-30 NCT04596085, NS-VC-CT01-20 Phase Not Applicable Recruiting 2 4 Months 124 Dr Ninad Naik, MD(Ayurveda), Dr. A Gopal Rao, MD Medcine, Dr. A Gopal Rao, MD(Med), Dr.Mahir Abduldaim, Dr.Ninad Naik, MD(Ayurveda), Muralidhar Gudla, Niranjan Andhalkar, Sohal Pendse 2020-10-28
APCC-19: Chemoprevention Clinical Trial of COVID-19: Hydroxychloroquine Post Exposure Prophylaxis Coronavirus disease 19 infection hydroxychloroquine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Farhat Hached University Hospital, Fattouma Bourguiba University Hospital Jordan 2020-10-27 2021-01-31 APCC-19, APCC-19, NCT04597775 Phase 2/Phase 3 Clinical Not yet recruiting 1 3 Months 93 Amer A Amous, MD, Munir A Abu-Helalah, PhD, Munir Abu-Helalah, PHD, Wissem Hachfi, MD 2020-10-27
Predicting the role of resilience, reactance, social solidarity and positive schemas on Pandemic-related Anxiety Anxiety disorder, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) LVR-Klinikum DüsseldorfKliniken der Heinrich-Heine-Universität Düsseldorf Germany 2020-11-01 2020-1071, DRKS00023321 Phase Not Applicable Not yet recruiting 1 85 Milenko Kujovic 2020-10-29
Prevalence and Temporal Evolution of Chest Radiographic Findings in Filipino Patients with Coronavirus Disease 2019 (COVID-19) Coronavirus disease 19 infection chest radiographic findings alone University of the Philippines Philippines 2020-05-15 2021-01-15 PHRR201012-003027 Phase not specified No longer recruiting 1 8 Months Jarold P. Pauig, Johanna Patricia Adevoso-Cañal, Julian A. Santos, Rosanna E. Fragante 2020-10-27
The Knowledge, Attitudes and Practices of Resident Physicians in Southern Philippines Medical Center, Davao City Philippines towards COVID-19: a cross-sectional study Coronavirus disease 19 infection Knowledge levels, attitudes and practices alone Southern Philippines Medical Center Philippines 2020-11-01 2020-12-01 PHRR201012-003017 Phase Not Applicable Not yet recruiting 1 1 Month Gleno Lon Q. Llamera, Pilar Mynthia B. Vicente, Shera Elefante 2020-10-27
VTE-COVID-19: Non-invasive Prognostication of COVID-19 Patients by Use of Biomarkers in Exhaled Breath Condensate Coronavirus disease 19 infection, Lung injury, Respiratory insufficiency exhaled breath condensate analysis alone, metabolomics analysis alone, proteomics analysis alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Aalborg Universitetshospital Aarhus University Hospital Skejby Denmark 2020-09-19 2021-10-01 ILG-VTE-COVID-19-2020, N-20200069, NCT04598620, VTE-COVID-19 Phase Not Applicable Recruiting 1 12 Months 50 Inger L Gade, MD, PhD, Lise T Elkjær 2020-10-27
Cytokine Storm Among Bangladeshi Patients With COVID-19 Coronavirus disease 19 infection, Inflammatory disease biological sampling alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry International Centre For Diarrhoeal Disease Research, Bangladesh Bangladesh 2020-10-31 2021-06-30 20084, ICDDR,B, NCT04598334 Phase Not Applicable Not yet recruiting 1 8 Months 75 Mohammod J Chisti, MBBS, PhD, Mohammod J Chisti, MBBS,PhD, Monira Sarmin, Monira Sarmin, MBBS, Monira Sarmin, MBBS, MCPS, Tahmeed Ahmed, MBBS, PhD 2020-10-29
Safety of Sofosbuvir/Daclatasvir in outpatients with COVID-19 Coronavirus disease 19 infection Sovodak, Fanavaran Rojan Mohaghegh Daru Co alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tehran University of Medical Sciences International Treatment Preparedness Coalition Iran 2020-10-24 IR.TUMS.DDRI.REC.1399.024, IRCT20200128046294N3 Phase 1/Phase 2 Clinical Recruiting 1 50 Anahita Sadeghi, Neda Alijani, Shahin Merat 2020-10-28
GlobalSurg-CovidSurg Week: Batangas Medical Center data Coronavirus disease 19 infection Philippines 2020-10-12 2021-04-12 PHRR201014-003031 Phase Not Applicable Not yet recruiting 1 6 Months Amabelle A. Moreno, MD 2020-10-28
Evaluation of the combination Ivermectin and Azithromycin as treatment in outpatients with COVID-19. Controlled clinical trial Coronavirus disease 19 infection ivermectin alone, azithromycin plus ivermectin Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Respiratory Diseases, Mexico Mexico 2020-11-03 C29-20 Phase 2 Clinical Status not specified 1 306 Arnoldo Aquino 2020-10-28
AcNT-COVID19: Immune Responses to COVID-19; Isolation of Neutralizing Antibodies for Therapeutics and Vaccine Coronavirus disease 19 infection Blood sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Grenoble Commissariat a l`Energie Atomique France 2020-04-30 2021-09-30 2020-A00904-35, 38RC20.132, AcNT-COVID19, NCT04596098 Phase Not Applicable Recruiting 2 17 Months 120 Benjamin NEMOZ, PHD, Djamila DURIN, engineer, Pascal POIGNARD, PHD, Pierre AUDOIN, engineer 2020-10-27
Antiviral Activity and Safety of Remdesivir in Bangladeshi Patients With Severe Coronavirus Disease (COVID-19) Coronavirus disease 19 infection, Respiratory distress syndrome remdesivir alone, standard of care alone COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Beximco Pharmaceuticals Ltd Bangladesh 2020-09-04 2021-01-31 BEX-06001, NCT04596839 Phase 2 Clinical Recruiting 1 4 Months 60 Dr. Md. Alimur Reza, Dr. Md. Alimur Reza, MBBS, MPH, Major General Md. Azizul Islam, Major General Md. Azizul Islam, MBBS, FCPS 2020-10-28
CAPTURE-2: Research and Evaluation of LumiraDx SARS-CoV-2 (COVID-19) Point of Care Ab Test Coronavirus disease 19 infection LumiraDx alone, SARS-CoV-2 Ab test alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) LumiraDx UK Ltd US 2020-08-20 2022-12-31 CAPTURE-2, NCT04597047, S-CLIN-PROT-0031 Phase Not Applicable Recruiting 4 28 Months 200 David Craig, Matthew Morgan, Melanie Hoppers, Vicki Kalen, William Simon 2020-10-28
NanoDxCoV19: Exploration of Feasability of Blood and Saliva Proteomic Analysis Through Harvesting by Silica Matrix Coronavirus disease 19 infection, Respiratory tract infection proteomic analysis alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Grenoble France 2020-10-15 2021-12-31 38RC20.289, NCT04597216, NanoDxCoV19 Phase Not Applicable Recruiting 1 14 Months 200 olivier EPAULARD 2020-10-28
NICOVID-REA: Evaluation of the Efficacy of Nicotine Patches in SARS-CoV2 (COVID-19) Infection in Intensive Care Unit Patients Coronavirus disease 19 infection nicotine alone Nicotinic acetylcholine receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris 2020-10-31 2021-10-31 2020-003723-42, APHP200537, NCT04598594, NICOVID-REA Phase 3 Clinical Not yet recruiting 0 12 Months 220 2020-10-27
Expanded Access Study of Exebacase in COVID-19 Patients With Persistent MRSA Bacteremia Coronavirus disease 19 infection, Endocarditis, MRSA infection antistaphylococcal antibiotic therapy alone, exebacase alone Hydrolase stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) ContraFect Corp US 2020-10-26 CF-301-107, NCT04597242 Phase Not Applicable Recruiting 1 Medical Director, ContraFect 2020-10-28
Schools Transmission Study (COVID-19 and Scarlet Fever) Coronavirus disease 19 infection, Group A Streptococcus infection biological sampling alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) Imperial College London Action Medical Research, National Institute for Health Research (NIHR) UK 2017-09-01 2025-03-31 CPMS 37059, IRAS 225006, ISRCTN13773960 Phase Not Applicable Recruiting 1 91 Months 344 Mrs Kerri Hill-Cawthorne, Prof Sriskandan 2020-10-28
A study to assess safety and efficacy UNI-91103 in patients affected with covid-19 Coronavirus disease 19 infection UNI-91103 alone Healthy volunteers accepted UNION therapeutics Phase Not Applicable Planned 0 44 2020-10-26
Evaluation of the Possible Vertical Transmission of SARS-CoV-2 Through Study of Amniotic Fluid and Chorionic Villi of Affected Pregnant Women for the COVID-19 Coronavirus disease 19 infection Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundacio Institut De Recerca De L'Hospital De La Santa Creu I Sant Pau Spain 2020-08-08 2022-01-23 IIBSP-COV-2020-59, NCT04598347 Phase Not Applicable Recruiting 1 17 Months 225 Obdulia Alejos Abad, PhD, MD, Obdulia Alejos, MD 2020-10-28
A prospective study to evaluate the accuracy of Cue COVID-19 Test in the diagnosis of COVID-19 infection Coronavirus disease 19 infection Cue COVID-19 Test alone Mayo Clinic Foundation Phase Not Applicable Status not specified 0 2020-10-26
A pivotal, phase III study of plitidepsin in patients with COVID-19, who require hospitalization Coronavirus disease 19 infection plitidepsin alone Elongation factor 1 alpha 2 modulator, VEGF-1 receptor modulator PharmaMar SA Phase 3 Clinical Planned 0 2020-10-26
A study of association of chest X-ray with clinical severity in hospitalized COVID-19 patients Coronavirus disease 19 infection, Hypoxia, Respiratory distress syndrome chest X-ray alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kasturba hospital, Manipal India 2020-10-31 CTRI/2020/10/028525 Phase Not Applicable Not yet recruiting 1 300 Nandakrishna B 2020-10-29
A phase III clinical trial of AT-527 to explore the potential use in patients outside of the hospital setting Coronavirus disease 19 infection AT-527 alone Hepatitis C virus NS5B polymerase inhibitor Atea Pharmaceuticals Inc, Roche Holding AG 2021-03-31 Phase 3 Clinical Planned 0 2020-10-27
Hematological and biochemical abnormalities parameters in the severity of COVID-19 Coronavirus disease 19 infection tocilizumab alone Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shree Krishna Hospital, pramukhswami medical college India 2020-10-30 CTRI/2020/10/028523 Phase Not Applicable Not yet recruiting 1 200 Dr Abdulrahman Amer, Dr Hitesh Shah 2020-10-27
COSEVAST study: To study the relationship of COVID-19 severity with blood vessels Cardiovascular disease, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Medical Sciences Patna India 2020-10-26 COSEVAST study, CTRI/2020/10/028489 Phase Not Applicable Not yet recruiting 1 75 Neeraj Kumar, Sanjeev Kumar 2020-10-29
RISEUP-PPD-COVID-19: Impact of COVID-19 Pandemic in Perinatal Mental Health Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder, Psychiatric disorder Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidade do Minho Bar-Ilan University, European University Cyprus, Havre Hospital, Instituto Presbiteriano Mackenzie, Instituto de Investigacion Biomedica de Malaga, Instituto de Saúde Pública da Universidade do Porto (ISPUP), King's College London, Mount Carmel Health System, Universidad Nacional De Educación A Distancia (UNED), Universidad de Huelva, Universidade Católica Portuguesa - Ucp, University of Athens, University of Coimbra, University of Malta, University of Sofia Portugal, Israel, France, Albania, Spain, UK, Turkey, Malta, Brazil, Bulgaria, Chile, Greece, Cyprus 2020-06-15 2021-06-15 NCT04595123, RISEUP-PPD-COVID-19, RISEUP-PPD-COVID-19 Phase Not Applicable Recruiting 13 12 Months 3900 Ana Mesquita, PhD, Ana Rita Carlos, Andry Christoforou, PhD, Angelique Picard, PhD, Camellia Hancheva, PhD, Claire Wilson, PhD, Eleni Vousoura, PhD, Emma Motrico, PhD, Erilda Ajaz, PhD, Ethel Felice, Dr, Pelin Dikmen-Yildiz, PhD, Rena Bina, PhD, Sandra M. Saldivia, PhD, Sara Dominguez, PhD, Vera Mateus, PhD 2020-10-29
The impact of COVID-19 pandemic on colorectal cancer therapy Colorectal tumor, Coronavirus disease 19 infection Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Japan 2020-08-15 UMIN000042211 Phase Not Applicable No longer recruiting 1 123 Mizuno Rei 2020-10-27
NETSCOV TRIAL: Role of blood cellular mechanism in severity of COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences Patna India 2020-10-26 CTRI/2020/10/028488, NETSCOV TRIAL Phase Not Applicable Not yet recruiting 1 60 Abhyuday Kumar 2020-10-28
COVIDCOLLECT: Relationship Between Biological Profiles and Clinical Evolutions Within the Same Cluster COVID-19 Coronavirus disease 19 infection RT-PCR alone Healthy volunteers accepted University Hospital Clermont-Ferrand France 2020-11-30 2022-02-28 2020-A02381-38, COVIDCOLLECT, NCT04597736, RBPH 2020 HENQUELL Phase Not Applicable Not yet recruiting 1 15 Months 100 Cécile Henquell, Céclie Henquell, Etienne Merlin, Lise LACLAUTRE, Lise Laclautre, Magali Vidal, Marc Berger, Olivier Lesens 2020-10-29
CEMS: To Study the safety of remdesivir in COVID-19 Patients Coronavirus disease 19 infection remdesivir alone COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences Patna India 2020-10-30 CEMS, CTRI/2020/10/028487 Phase Not Applicable Not yet recruiting 1 100 Dr Aakanksha Priya, Dr Shruti Singh 2020-10-27
CONSERVE-HCW: Changes in Seroprevalence and Wellness Over Time in Healthcare Workers Coronavirus disease 19 infection bbott Architect SARS-CoV-2 IgG assay alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) St. Joseph's Hospital and Medical Center Chandler Regional Medical Center, Dignity Health, Mercy Gilbert Medical Center US 2020-06-10 2021-12-30 20-510-157-66-21, CONSERVE-HCW, NCT04595175 Phase Not Applicable Recruiting 1 18 Months 2000 Andrea B. Garcia, MBA, Andrea Garcia, MBA, Brian Tiffany, Brian Tiffany, MD, PhD, Jennine Zumbuhl, RN, MSHA 2020-10-28
COVID-RT-01: Low Dose Radiation Therapy for Severe-Acute-Respiratory-Syndrome-Coronavirus-2 (SARS-CoV-2) Coronavirus disease 19 infection low dose radiation therapy (1 Gray) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Basel Switzerland 2020-11-30 2021-11-30 2020-02047QU20PAPACHRISTOFILOU, COVID-RT-01, NCT04598581 Phase Not Applicable Recruiting 1 12 Months 22 Alexandros Papachristofilou, Dr. med., Martin Siegemund, Prof. Dr. med., Tobias Finazzi, Dr. med. 2020-10-27
LungMechCoV-19: Assessment of Lung Mechanics in COVID-19 Acute Respiratory Distress Syndrome Coronavirus disease 19 infection, Respiratory failure Impedance tomography alone, indirect calorimetry alone, right-heart catheterization alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Zurich 2020-10-20 2021-12-31 2020-01999, LungMechCoV-19, NCT04597853 Phase Not Applicable Not yet recruiting 0 14 Months 25 Philipp K Buehler, MD 2020-10-28
FIPPS: Trial of financial incentives for preventing postpartum return to smoking Coronavirus disease 19 infection, Nicotine dependence financial incentive alone Female, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Of Stirling UK 2018-02-01 2022-11-30 FIPPS, ISRCTN55218215, VERSION 6.0 Phase Not Applicable Recruiting 5 58 Months 900 Prof Ussher 2020-10-28
Challenges faced by PG students in conducting research Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kasturba Medical College and Hospital India 2020-10-26 CTRI/2020/10/028520 Phase Not Applicable Not yet recruiting 1 800 Divya Karanth 2020-10-27
Treatment of SARS-CoV-2 Virus Disease (COVID-19) in Humans With Hemopurifier Device Acute lung injury, Coronavirus disease 19 infection, Multiple organ failure, Respiratory distress syndrome, Respiratory failure, Septic shock Hemopurifier alone, arteriovenous fistula treatment alone, double-lumen hemodialysis catheter alone, extracorporeal therapy alone, graft treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Aethlon Medical Inc US 2020-10-31 2021-08-31 AEMD-2020-02, NCT04595903 Phase Not Applicable Not yet recruiting 1 10 Months 40 Lisa Boswell, Timothy C Rodell, MD, Usman Shah, MD 2020-10-29
A clinical study to assess AZD-7442 in the treatment of subjects with COVID-19 Coronavirus disease 19 infection AZD-7442 alone COVID19 Spike glycoprotein inhibitor AstraZeneca plc Biomedical Advanced Research and Development Authority (BARDA) Phase Not Applicable Planned 0 4000 2020-10-23
Impact of Covid-19 on mental health among health care workers Coronavirus disease 19 infection, Psychiatric disorder Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Indira Gandhi Medical College India 2020-12-01 CTRI/2020/10/028524 Phase 3 Clinical Not yet recruiting 1 632 Shabnum Thakur 2020-10-28
Yoga for COVID-19 Patients with mild symptoms Coronavirus disease 19 infection, Respiratory tract infection Yoga modules intervention alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mahatma Gandhi Memorial Medical College, Indore, Swami Vivekananda Yoga Anusandhana Samsthana Svyasa India 2020-11-02 CTRI/2020/10/028486 Phase 1 Clinical Not yet recruiting 1 50 Dr Satyapriya Maharana, Pragya Jain Shrimal 2020-10-27
Endoscopic Procedures of Children in the Normalization Process of Covid-19 Pandemic Coronavirus disease 19 infection, Gastrointestinal disease COVID-19 PCR test alone, chest radiography alone, endoscopy alone, thorax computed tomography alone Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Tepecik Training and Research Hospital Turkey 2020-06-01 2020-08-31 NCT04598256, TEPECIKTRH1 Phase Not Applicable Completed 1 3 Months 77 BETÜL AKSOY, MD, DİLEK YILMAZ ÇİFTDOĞAN, PROFESSOR, MAŞALLAH BARAN, PROFESSOR, YELİZ ÇAĞAN APPAK, MD, ŞENAY ONBAŞI KARABAĞ, MD 2020-10-29
Relation of lung disease and smoking with the severity of COVID-19 in a district hospital of Pune city, Maharashtra Chronic obstructive pulmonary disease, Coronavirus disease 19 infection, Nicotine dependence Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Byramjee Jeejeebhoy Govt Medical College and Sassoon General Hospitals India 2020-10-26 CTRI/2020/10/028470 Phase Not Applicable Not yet recruiting 1 489 Dr Malangori Parande, MINAL HATNAPURE 2020-10-29
Investigating the efficacy and safety of Myrtus nasal spray in controlling the symptoms of patients with mild COVID-19 Coronavirus disease 19 infection Myrtus inhalation spray alone, routine treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bagheiat-allah University of Medical Sciences Iran 2020-07-22 IR.BMSU.REC.1399.159, IRCT20080901001165N63 Phase 3 Clinical No longer recruiting 1 100 Gholamhosein Alishiri, Parisa Kianpour, Seyed Mohamad Javad Hosseini, Yunes Panahi 2020-10-27
Evaluation of short term outcomes of liver transplantation from COVID-19 positive deceased donors Acute liver failure, Coronavirus disease 19 infection liver transplantation alone Mashhad University of Medical Sciences Iran 2020-10-01 IR.MUMS.REC.1399.442, IRCT20200928048867N1 Phase Not Applicable Recruiting 1 10 Mohsen Aliakbarian, Mohsen Tafaghodi, Sara Saeidi Shahri 2020-10-28
CovidSat@Home: A randomized, controlled pilot trial investigating the feasibility and safety of monitoring patients with or at risk for cardiovascular disease who have symptoms suspected of COVID-19 by pulse oximetry at home Coronavirus disease 19 infection, Hypoxia home monitoring of blood oxygen levels alone, pulse oximeter alone, usual (primary) care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitair Medisch Centrum Utrecht Dutch Heart Foundation Netherlands 2020-11-01 2021-06-01 CovidSat@Home, NL8954 Phase Not Applicable Not yet recruiting 1 7 Months 50 Dorien Zwart 2020-10-27
EPICS-14: Point of Care Influenza screening and SARS-CoV-2 (COVID-19) testing in the Emergency Department Coronavirus disease 19 infection, Influenza virus infection COVID-19 testing alone, Influenza A/B point-of-care screening test alone, cobas Liat system alone, multiplex real-time polymerase chain reaction test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Charite Universitaetsmedizin Berlin Roche Molecular Systems Inc Germany 2019-12-17 DRKS00019207, EA2/204/19, EPICS-14, EPICS-14 Phase Not Applicable Recruiting 1 3000 Martin Mockel 2020-10-27
Yoga for COVID-19 healthcare workers Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection Yoga alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Swami Vivekananda Yoga Anusandhana Samsthana Svyasa India 2020-11-02 CTRI/2020/10/028485 Phase 1 Clinical Not yet recruiting 1 100 Dr Satyapriya Maharana, Pragya Jain Shrimal 2020-10-29
COVAED: Study of Edaravone as adjunctive treatment in COVID Coronavirus disease 19 infection edaravone alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) India 2020-10-29 COVAED, CTRI/2020/10/028472 Phase 2 Clinical Not yet recruiting 1 40 Dr John Paul M 2020-10-29
Systematic Review - COVID-19 Coronavirus disease 19 infection Corticosteroids therapy alone, tocilizumab alone Pulau Pinang Hospital Malaysia 2020-11-01 2021-11-01 56296, NMRR-20-2263-56296 Phase Not Applicable Status not specified 1 12 Months DR Sivasangari Subramaniam, Lim Phei Ching 2020-10-28
ASTERIX: An observational study to identify sub-groups of COVID-19 patients based on their demographic, clinical and laboratory profile, and to determine if these sub-groups can be used to predict severity of disease and response to therapy Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) NHS Greater Glasgow and Clyde National Institute for Health Research (NIHR), Scottish Government Health and Social Care Directorates UK 2020-04-01 2021-01-01 ASTERIX, CPMS 46231, IRAS 283151, ISRCTN66141262 Phase Not Applicable Recruiting 2 9 Months 600 Mrs Evans 2020-10-29
Relationships between physical activity during hospitalization and physical capacity after discharge from hospital in patients with COVID-19: a prospective, observational study Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Wakayama Medical University Japan 2020-11-15 UMIN000042214 Phase Not Applicable Not yet recruiting 1 40 Masakazu Minetama, Tadashi Sumiya 2020-10-27
Effect of the drug 'Immune'- an Ayurveda medication in COVID-19 patients Coronavirus disease 19 infection Variable regimens including Aswagandha , Devadaaru , Jeevanthi , Yashthimadu Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Sathayush Ayurvedic India Private Limited India 2020-11-02 CTRI/2020/10/028471 Phase 2 Clinical Not yet recruiting 1 50 DrSudha Bala, Sailaja Vani 2020-10-27
A phase Ib clinical trial to evaluate the safety, tolerance and preliminary immunogenicity of different doses of a novel coronavirus pneumonia (COVID-19) mRNA vaccine in population aged 18 to 59 years Coronavirus disease 19 infection, Viral pneumonia SARS-CoV-2 mRNA vaccine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Chinese Academy of Medical Military Sciences, Suzhou Abogen Biosciences China 2020-10-28 2021-12-31 ChiCTR2000039212 Phase 1b Clinical Not yet recruiting 1 14 Months 1200 Lin Yuan, Shuyuan Yang 2020-10-27
Yoga for COVID-19 asymptomatic patients Coronavirus disease 19 infection Tele based yoga alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Swami Vivekananda Yoga Anusandhana Samsthana Svyasa India 2020-11-02 CTRI/2020/10/028566 Phase 1 Clinical Not yet recruiting 1 60 Dr Satyapriya Maharana, Pragya Jain Shrimal 2020-10-27
IND-02 for prevention against SARS-CoV-2 Infection: A Randomized, controlled study in moderate to high risk population Coronavirus disease 19 infection IND-02 alone ApoB editing catalytic polypeptide 3G modulator, HIV gp120 protein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Indus Biotech Pvt Ltd India 2020-10-29 CTRI/2020/10/028547, IND02-NASAL-PROPHYLAXIS Phase 2/Phase 3 Clinical Not yet recruiting 5 258 Dr A Venkateshwar Rao, Dr Deepak B Varade, Dr Kapil Patwardhan, Dr Manish Rajak, Dr Nidhi Anand, Dr Prasad Thakurdesai, Dr Sonali Nirhali 2020-10-28
High-flow nasal cannula oxygen in adult patients of COVID-19 admitted to intensive care units. Coronavirus disease 19 infection igh-flow nasal cannula oxygen therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Lok Nayak Hospital India 2020-10-28 CTRI/2020/10/028539 Phase Not Applicable Not yet recruiting 1 70 sukhyanti kerai 2020-10-27
Clinical trial of Ayurvedic Medicines in Patients with Asymptomatic and/or Mild Symptoms of COVID-19 Coronavirus disease 19 infection Chyawanprash alone, Immuncoction alone, Standard medicine therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) India 2020-10-22 CTRI/2020/10/028537, MHC/CT/20-21/011 Phase 2 Clinical Not yet recruiting 2 90 Dr Anurag Gupta, Prof NS Sengar 2020-10-27
Semen Analysis Changes in Covid-19 Positive patients Coronavirus disease 19 infection Semen analysis alone Healthy volunteers accepted, Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Assiut University Egypt 2020-05-01 2020-10-15 NCT04595240, SEMEN ANALYSIS POST COVID-19 Phase Not Applicable Completed 1 5 Months 100 ahmed a abdel moniem, md, mostafa kamel abdel rahman abdel aal 2020-10-27
ADDIMTCOVID: Inspiratory Muscle Training in COVID-19 Patients Coronavirus disease 19 infection PowerBreathe KHP2 alone, endurance training alone, inspiratory muscle training alone, interval training alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundação de Ensino e Pesquisa em Ciências da saude Conselho Nacional de Desenvolvimento Cientifico e Tecnologico - CNPq, Jbs Sa, University of Brasilia Brazil 2020-11-01 2021-06-30 ADDIMTCOVID, CNPQ092020, NCT04595097 Phase Not Applicable Not yet recruiting 1 8 Months 120 Vinicius Maldaner, Vinicius Zacarias Maldaner da silva 2020-10-27
Irbesartan and Oseltamivir treatment of COVID-19 infection Coronavirus disease 19 infection irbesartan plus oseltamivir Angiotensin II AT-1 receptor antagonist, Exo-alpha sialidase inhibitor Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Slagelse Hospital Denmark 2020-09-16 2020-001610-38, JAGG2020-1 Phase 4 Clinical Recruiting 1 80 2020-10-27
Treatment and followup outcomes of gynecological cancer patients treated with radiation therapy during lockdown phase of COVID pandemic Cancer, Coronavirus disease 19 infection radiation therapy alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tata Memorial Centre India 2020-10-30 CTRI/2020/10/028571 Phase Not Applicable Not yet recruiting 1 1500 Dr Supriya Chopra 2020-10-28
To study the effect of Vyaghradi Kashay tablet on COVID-19 patients Coronavirus disease 19 infection Vyaghradi Kashay alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ministry of Ayush Ayurvedic and Unani Tibbia College India 2020-11-05 CTRI/2020/10/028570 Phase 2/Phase 3 Clinical Not yet recruiting 1 30 Dr Manoj Shamkuwar, Dr Nitin Jindal 2020-10-23
Challenges for healthcare workers with infection control practices during COVID-19 pandemic Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) AIIMS Jodhpur India 2020-10-26 CTRI/2020/10/028569 Phase Not Applicable Not yet recruiting 1 200 Anuradha Sharma 2020-10-27
COVID-19: Study to Evaluate the Efficacy of COVID-19-0001-USR in Patients With Mild/or Moderate COVID-19 Infection in Outpatient Coronavirus disease 19 infection COVID-19-0001-USR alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Colombia 2020-11-02 2021-01-29 COVID-19, COVID19-0001-USR, NCT04595136 Phase 1/Phase 2 Clinical Not yet recruiting 1 2 Months 60 Carlos A Riveros, MD, Juan Jaller, MD 2020-10-23
Trends in suicide rates during the Covid-19 pandemic quarantine Coronavirus disease 19 infection, Suicide Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) UniversitätsKlinikum Leipzig Germany 2020-06-24 272/20-ek, DRKS00022536 Phase Not Applicable Recruiting 1 500 Daniel Radeloff 2020-10-24
Clinical Study to Evaluate the Effects of Disulfiram in Patients With Moderate COVID-19 Coronavirus disease 19 infection disulfiram (Antabuse) alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Brazil 2020-10-31 2021-04-30 NCT04594343, SPR-001-201 Phase 2 Clinical Not yet recruiting 1 6 Months 200 Augusto Mota, MD/PhD, Wendy Cousin, PhD 2020-10-24
Dosing of Thromboprophylaxis and Mortality in Critically Ill COVID-19 Patients Bleeding, Coronavirus disease 19 infection, Respiratory failure, Thromboembolism dalteparin sodium alone, tinzaparin sodium alone Antithrombin III, Factor IIa antagonist, Factor Xa antagonist, Low molecular weight heparin Karolinska Institutet Sweden 2020-03-01 2020-10-15 NCT04593654, THROMBOPROPHYLAXIS COVID-19 Phase Not Applicable Completed 1 7 Months 257 Sandra Jonmarker, MD 2020-10-27
Teledermatology during the COVID-19 pandemic: A retrospective descriptive study Acne vulgaris, Coronavirus disease 19 infection, Eczema, Psoriasis, Skin cancer, Skin infection, Urticaria, Vasculitis, Venous insufficiency Southern Philippines Medical Center Philippines 2020-11-01 2020-12-01 PHRR201015-003037 Phase Not Applicable Recruiting 1 1 Month Anna Cristina L. Cuenca, Jen-Christina Segovia, MD, Lalaine R. Visitacion, MD, FPDS 2020-10-27
Evaluate Safety and Efficacy of RV Forte Capsule as an immunomodulator in adult Covid 19 positive patients Coronavirus disease 19 infection RV Forte alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) India 2020-10-26 CTRI/2020/10/028568, MHC/CT/20-21/007 Phase 2 Clinical Not yet recruiting 1 60 Dr Gayatri Gnau, Dr V G Vaidya 2020-10-27
Virgin Coconut Oil (VCO) as a Potential Adjuvant Therapy in COVID-19 Patients Coronavirus disease 19 infection, Viral pneumonia virgin coconut oil alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Gadjah Mada Indonesia 2020-06-01 2020-12-31 002/05/2020, NCT04594330 Phase 2 Clinical Recruiting 4 7 Months 60 Desy NP, MD, Eko Purnomo, MD, PhD, surgeon, Ika Trisnawati, MD, MSc, internist, Nur R Ananda, MD, internist-pulmonologist, Paulus Wisnu, MD, pulmonologist 2020-10-27
Red cell antibody profile in Covid-19 Coronavirus disease 19 infection Direct antiglobulin test alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Seth GS Medical College India 2020-11-01 CTRI/2020/10/028567 Phase Not Applicable Not yet recruiting 1 200 Dr Swarupa Nikhil Bhagwat 2020-10-23
Study of the Safety of Prophylactic Vaccination With Second Generation E1/E2B/E3-Deleted Adenoviral-COVID-19 in Normal Healthy Volunteers Coronavirus disease 19 infection recombinant bivalent second-generation adenovirus (hAd5) vector-delivered SARS-CoV-2 S + N protein vaccine (oral, COVID-19), ImmunityBio alone, recombinant bivalent second-generation adenovirus (hAd5) vector-delivered SARS-CoV-2 S + N protein vaccine (subcutaneous, COVID-19), ImmunityBio alone COVID19 Spike glycoprotein modulator, COVID19 nucleoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) ImmunityBio Inc US 2020-10-19 2021-11-19 NCT04591717, QUILT-COVID-19-HAD5-VACCINE Phase 1b Clinical Recruiting 1 13 Months 35 Deborah Fridman, Lennie Sender 2020-10-27
A pivotal, phase III, randomized, double-blind, placebo-controlled trial of an interferon-beta (IFN-beta), SNG-001 treatment in the treatment of patients hospitalized with COVID-19 Coronavirus disease 19 infection inhaled interferon beta (lung disorders/influenza), Synairgen alone Interferon beta ligand PAREXEL International Synairgen plc Phase 3 Clinical Planned 0 900 2020-10-29
Outcomes of Elective Colorectal Cancer Surgery During COVID 19 Pandemic: Implications for Cancer Care Policy Colorectal tumor, Coronavirus disease 19 infection Colorectal resection alone Sher-i-Kashmir Institute of Medical Sciences India 2020-03-23 2020-10-22 73/2020 (SUPL 2), NCT04588909 Phase Not Applicable No longer recruiting 1 7 Months 100 ASIF MEHRAJ, Senior Resident, Nisar A Chowdri 2020-10-24
NET_COV: Assessment of Netosis During COVID-19, Under Treatment With Anakinra, an Interleukin-1 Receptor Antagonist Coronavirus disease 19 infection, Inflammatory disease anakinra alone Type I IL-1 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Groupe Hospitalier Paris Saint-Joseph France 2020-11-19 2021-06-30 NCT04594356, NET_COV, NET_COV Phase Not Applicable Not yet recruiting 1 7 Months 126 Gilles HAYEM, MD, Helene BEAUSSIER, PharmD, pHD, Sylvie CHOLLET MARTIN, MD 2020-10-27
This is a Phase I Study to Evaluate the Safety, Tolerability and Virology of CT-P59 in Patients With Mild Symptoms of Symptoms of Coronavirus Disease (COVID-19) Coronavirus disease 19 infection CT-P59 alone COVID19 Spike glycoprotein inhibitor, Moesin modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Celltrion Healthcare Co Ltd, Celltrion Inc South Korea 2020-09-04 2020-12-23 2020-003165-19, CT-P59 1.2, NCT04593641 Phase 1 Clinical No longer recruiting 1 3 Months 18 2020-10-23
Hydrogen-oxygen Gas Mixture Inhalation in Patients With Convalescent Coronavirus Disease 2019 (COVID-19) Coronavirus disease 19 infection, Viral pneumonia AMS-H-03 alone, hydrogen-oxygen gas alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Guangzhou Institute Of Respiratory Disease China 2020-10-31 2021-12-31 AMS-H-03-101, NCT04594460 Phase 2 Clinical Not yet recruiting 2 14 Months 198 Wei-jie Guan, PhD 2020-10-25
Impact of COVID-19 on Pediatric Dental Practice In Egypt Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Cairo University Egypt 2021-02-28 2022-01-31 NCT04592510, Y66CYYG6 Phase Not Applicable Not yet recruiting 1 11 Months 290 Adel El Bardissy, Fatma Essam El-Deen, Fatma Essam El-Deen Abdel Rahim, Shaimaa Sabry 2020-10-22
COVID-19 human challenge study Coronavirus disease 19 infection test vaccines alone Healthy volunteers accepted, Young Adults (18-44 yrs) Imperial College London, Open Orphan PLC UK Government, hVIVO plc UK Phase Not Applicable Planned 1 2020-10-22
MuCo: Mucosal Immunity Against SARS-CoV-2 Infection in COVID-19 Patients Coronavirus disease 19 infection biological sampling alone Radboud University Netherlands 2020-03-26 2020-05-13 2020-6342, MuCo, NCT04590352, NL73418.091.20 Phase Not Applicable Completed 1 1 Month 187 Dimitri Diavatopoulos, Dr 2020-10-23
EMO-COVID: Hemostatic Profile in Patients Affected by COVID-19 Coronavirus disease 19 infection, Thrombosis Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ospedale Papa Giovanni XXIII Italy 2020-03-25 2021-05-10 EMO-COVID, EMO-COVID-ASSTPG23, NCT04595110 Phase Not Applicable Recruiting 1 13 Months 400 ANNA FALANGA, Anna Falanga, MD, Laura Russo, BSc 2020-10-27
Propolis supplementation And Coronavirus Coronavirus disease 19 infection Propolis supplementation (Reyhan Naghsh Jahan Pharmaceutical Co) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Isfahan University of medical Sciences Iran 2020-08-22 IR.MUI.MED.REC.1399.337, IRCT20200802048267N1 Phase 2 Clinical Recruiting 1 80 Karim Sohrabi, Shaghayegh Haghjooy 2020-10-23
MRI-AIDED: MRI Changes of Acute Kidney Injury in COVID-19 Coronavirus disease 19 infection, Renal injury MRI scans alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospitals Of Derby and Burton NHS Foundation Trust NIHR Nottingham Biomedical Research Centre UK 2020-10-07 2023-09-30 287571, MRI-AIDED, NCT04594291, UHDB/2020/077 Phase Not Applicable Recruiting 1 35 Months 60 Maarten Taal, Professor, Nicholas Selby, Professor 2020-10-24
Defining the COVID-19 Immunity Denominator in the Mekong: a Cross-Sectional Seroprevalence Study of SARS-CoV-2 in Healthy Volunteers Coronavirus disease 19 infection ELISA alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) National Institute of Allergy and Infectious Diseases National Institutes of Health Clinical Center Cambodia 2020-11-02 2023-12-31 000083-I, 10000083, NCT04594395 Phase Not Applicable Recruiting 2 37 Months 2700 Jessica E Manning, M.D., Ly Sovann, Suon Seila, M.D. 2020-10-29
A propensity score matched, retrospective, cohort study to evaluate the effect of famotidine on the clinical outcomes of hospitalized patients with COVID-19 Coronavirus disease 19 infection famotidine alone, proton pump inhibitors alone Histamine H2 receptor antagonist Columbia University US Phase Not Applicable Status not specified 1 1620 2020-10-22
A late stage clinical trial of intranasal CodaVax-COVID for the prevention of Covid-19 Coronavirus disease 19 infection CodaVax-COVID alone Bharat Biotech International Ltd, Serum Institute of India Ltd Phase Not Applicable Planned 0 2020-10-22
COVIDWHELD: Improving Wellbeing and Health for Care Home Residents During COVID-19 Coronavirus disease 19 infection, Dementia COVID WHELD alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Exeter University Alzheimers Society, King's College London, London School of Economics and Political Science, University of East Anglia, University of Hull 2020-11-20 2022-01-01 20-21-10, COVIDWHELD, NCT04590469 Phase Not Applicable Not yet recruiting 0 13 Months 2880 Clive Ballard, MD, Clive G Ballard, MD, Dag Aarsland, MD 2020-10-24
MyeloidCovid: Myeloid Cells in Patients With COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia blood sampling alone, nasal brushing alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Assistance Publique Hopitaux de Paris INSERM India 2020-11-01 2023-11-01 2020-A02700-39, APHP201138, MyeloidCovid, NCT04590261 Phase Not Applicable Not yet recruiting 1 36 Months 120 Marie BENHAMMANI-Godard, Pierre-Régis Burgel, MD, PhD 2020-10-23
Study to Assess the Safety, Tolerability, and Pharmacokinetics of HFB-30132A Against COVID-19 in Healthy Adults Coronavirus disease 19 infection HFB-30132A alone Angiotensin converting enzyme 2 inhibitor, COVID19 Spike glycoprotein inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) HiFiBio US 2020-10-31 2021-07-31 HFB30132A-101, NCT04590430 Phase 1 Clinical Recruiting 1 9 Months 24 Francisco Adrian, Kari LaSalvia, Leela Vrishabhendra, MD 2020-10-28
COGCOV: The COGCOV Study in ICU Patients Cognitive disorder, Coronavirus disease 19 infection, Neurological disease Neurocognitive assessment alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ziekenhuis Oost-Limburg Belgium 2020-10-07 2021-02-28 COGCOV, COGCOV, NCT04593069 Phase Not Applicable Recruiting 1 4 Months 60 Dieter Mesotten, MD, Elly Vandermeulen, Elly Vandermeulen, PhD 2020-10-24
Evaluating an Online Wellness Intervention for Indian College Students Anxiety disorder, Coronavirus disease 19 infection, Depression Common Elements Toolbox alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Pennsylvania India 2020-10-19 2021-06-30 843879, NCT04592588 Phase Not Applicable Recruiting 1 8 Months 300 Akash Wasil, Tavni Malhotra 2020-10-28
A retrospective, cross-sectional study to evaluate the lopinavir/ritonavir and interferon combination therapy effects on shortening the duration of viral shedding in COVID-19 patients Coronavirus disease 19 infection interferon-gamma plus lopinavir + ritonavir HIV protease inhibitor Anhui Medical University China Phase Not Applicable Status not specified 1 181 2020-10-22
Testing Multiple Behavioral Science Strategies to Increase Flu-Shot Rates at a Large Retail Pharmacy Coronavirus disease 19 infection, Influenza virus infection flu shot text messages alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Pennsylvania US 2020-09-25 2020-12-31 843523-TRIAL B, NCT04590066 Phase Not Applicable No longer recruiting 1 3 Months 1200000 2020-10-23
ACROCOVID: Clinical and Mechanistic Study of Patients (With COVID-19 or Not) With a Recent Acrosyndrome Coronavirus disease 19 infection blood sampling alone, skin biopsy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris Cochin Institute France 2020-10-31 2020-12-31 ACROCOVID, APHP200884, NCT04590209, N° IDRCB 2020-A0181336 Phase Not Applicable Not yet recruiting 1 2 Months 25 Marie Benhammani-Godard, Nicolas Dupin, MD, PhD, Sélim Aractingi, MD, PhD 2020-10-24
PRONE-COVID: Prone Position to Improve Oxygenation in COVID-19 Patients Outside Critical Care Coronavirus disease 19 infection, Viral pneumonia Prone positioning alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cambridge University Hospitals NHS Foundation Trust UK 2020-09-03 2021-06-30 284061, NCT04589936, PRONE-COVID Phase Not Applicable Recruiting 1 9 Months 56 Akhilesh Jha, Andrew Ying, Celine Goh, Chen Zhang, Fangyue Chen, Iain Goodhart, Jonathan Fuld, Kate Fitzpatrick, Marie Fisk, Sam Mann 2020-10-23
Using Telemedicine to Optimize Teamwork and Infection Control of Critical and Highly-infectious Patients in an Emergency Department Coronavirus disease 19 infection telemedicine based communication alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Taiwan University Hospital Taiwan 2020-10-10 2021-10-30 202007114RINA, NCT04591873 Phase Not Applicable Not yet recruiting 1 12 Months 100 Chien-Hao Lin, MD 2020-10-24
An observational, longitudinal, prospective cohort study on the predictive factors for cardiac conduction abnormalities with hydroxychloroquine-containing combinations for COVID-19 Cardiovascular disease, Coronavirus disease 19 infection Variable regimens including azithromycin , hydroxychloroquine , lopinavir + ritonavir HIV protease inhibitor Hospital General Universitario De Elche Phase Not Applicable Status not specified 0 105 2020-10-22
A clinical trial of plasma-derived anti-SARS-CoV-2 IgG (COVID-19), Kedrion Biopharma/Kamada in the treatment of patients with COVID-19 infection Coronavirus disease 19 infection plasma-derived anti-SARS-CoV-2 IgG (COVID-19), Kedrion Biopharma/Kamada alone Kamada Ltd US Phase Not Applicable Planned 1 2020-10-22
ARCTIC: Aerosolized Inhaled Adenosine Treatment in Patients With Acute Respiratory Distress Syndrome (ARDS) Caused by COVID-19 Blood clotting disorder, Coronavirus disease 19 infection, Lung inflammation, Respiratory distress syndrome, Respiratory tract infection Aerogen nebulizer alone, adenosine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Florida US 2020-12-31 2022-12-31 ARCTIC, IRB202002127, NCT04588441, OCR39505 Phase 2 Clinical Not yet recruiting 1 24 Months 30 Amy Gunnett, Bruce Spiess 2020-10-23
MAOi-COV19: Impact of a Monoamine Oxidase Inhibitor on the Phenotype of Blood Mononucleated Cells in Patients With COVID-19 Coronavirus disease 19 infection phenelzine (Nardil) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-11-30 2021-11-30 2020-A02398-31, APHP200989, MAOi-COV19, NCT04590222 Phase Not Applicable Not yet recruiting 1 12 Months 80 Katia BOURDIC, Olivier LAMBOTTE, Olivier LAMBOTTE, Prof 2020-10-23
Expressive Writing for COVID-19 Resilience Acute stress disorder, Coronavirus disease 19 infection, Depression virtually-delivered expressive writing alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Duke University US 2020-05-26 2020-08-17 NCT04589104, PRO00105575 Phase Not Applicable Completed 1 2 Months 63 Oliver Glass, PhD 2020-10-21
Supporting Family Members With Severe Grief Reaction During the COVID-19 Pandemic Coronavirus disease 19 infection, Psychiatric disorder Bereavement Virtual Support alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ottawa Hospital Research Institute Canada 2020-11-01 2022-01-01 20200653-01H, NCT04588415 Phase Not Applicable Not yet recruiting 1 14 Months 200 Antoine Przybylak-Brouillard, Peter Lawlor 2020-10-21
COVID-19-DM: The Effect of COVID-19 on Diabetes Mellitus Coronavirus disease 19 infection, Diabetes mellitus Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Usak University, Turkey Turkey 2020-03-20 2020-11-01 COVID-19-DM, NCT04592055, UU-DM002 Phase Not Applicable Recruiting 1 7 Months 500 Cevdet Duran, Cevdet Duran, Prof 2020-10-23
ACTIV-1 IM: Immune Modulators for Treating COVID-19 Coronavirus disease 19 infection Variable regimens including abatacept , cenicriviroc , infliximab , remdesivir CCR2 chemokine antagonist, CCR5 chemokine antagonist, COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, Cytotoxic T-lymphocyte protein-4 stimulator, RNA polymerase modulator, T cell surface glycoprotein CD28 inhibitor, TNF alpha ligand inhibitor, TNF binding agent Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Duke University Biomedical Advanced Research and Development Authority (BARDA), Duke Clinical Research Institute, Fisher Bioservices, National Center For Advancing Translational Sciences, National Institutes of Health, Syneos Health Inc, Technical Resources International US 2020-10-15 2021-09-30 ACTIV-1 IM, NCT04593940, PRO00106301 Phase 3 Clinical Recruiting 2 11 Months 2190 Cameron Wolfe, Cameron Wolfe, MD, Daniel K Benjamin, MD, PhD, Jane O'Halloran, Jane O'Halloran, MD, Lori Hudson, PhD, Theresa Jasion, MS, William G. Powderly 2020-10-27
A phase II clinical study to assess Nylexa in the treatment of patients with COVID-19 Coronavirus disease 19 infection mercaptamine (parenteral, COVID-19), NovaBiotics alone NovaBiotics Ltd Technology Strategy Board Phase 2 Clinical Planned 0 2020-10-21
A case-report study in the evaluation of FDG-PET/CT in a patient with COVID-19 Coronavirus disease 19 infection 18F-FDG alone, PET/CT alone, albumin alone, budesonide alone, hydroxychloroquine hydrochloride alone, interferon alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Zhengzhou University Phase Not Applicable Status not specified 0 1 2020-10-23
FaST-1: Furosemide as Supportive Therapy for COVID-19 Respiratory Failure Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia nebulized furosemide alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Queen's University University Health Network Toronto Canada 2020-10-19 2021-10-01 FAST-1, FaST-1, NCT04588792 Phase 2/Phase 3 Clinical Not yet recruiting 4 11 Months 640 Dave Maslove, MD, Gordon Boyd, MD, HT Wand, MD, John Muscedere, MD, Oleksa Rewa, MD, Osama Loubani, MD, Stephanie Sibley, MD, Tracy Boyd 2020-10-23
Mindfulness to Mitigate Psychological Threat and Improve Engagement and Learning in Introductory Physics Courses Coronavirus disease 19 infection, Psychiatric disorder Mindfulness Training alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Pittsburgh James S McDonnell Foundation, National Science Foundation US 2020-10-12 2022-12-31 NCT04589377, STUDY19050258 Phase Not Applicable Recruiting 1 26 Months 150 Brian Galla, PhD, Sara Jahanian, BS, Timothy Nokes-Malach, PhD 2020-10-21
Expressive Writing for COVID-19 Resilience for Parents Acute stress disorder, Coronavirus disease 19 infection, Depression Expressive writing alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Duke University US 2020-05-27 2020-08-02 NCT04589117, PRO00105586 Phase Not Applicable Completed 1 2 Months 11 Oliver Glass, PhD 2020-10-27
The Peer-Delivered "Mind. Body. Voice." Program for High School Women (Mbv) - Remote Coronavirus disease 19 infection, Eating disorder mind, body, voice program alone Healthy volunteers accepted, Female University of Colorado US 2020-10-09 2031-05-31 18-0007-03, NCT04591912 Phase Not Applicable Recruiting 1 127 Months 140 Bernadette Park, PhD, Gavin Bell, BA, Leah Pena Teeters, PhD, Leah Teeters, PhD, Sona A Dimidjian, PhD, Sona Dimidjian 2020-10-21
COCO-LATE: Late Clinical Events Associated With COVID-19 Infection Coronavirus disease 19 infection Biocollection alone, Follow-up visit alone, Questionnaire alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier de Tourcoing France, French Guiana 2020-10-31 2022-08-31 COCO-LATE, NCT04591613, RIPH_2020_09 Phase Not Applicable Not yet recruiting 17 22 Months 1000 Clara FLATEAU, Cédric JOSEPH, David CHIRIO, Delphine POITRENAUD, Dominique SALMON, Elisabeth BOTELHO-NEVERS, François GOEHRINGER, Louis BERNARD, Marie GOUSSEFF, Marie PICHENOT, Nicolas VIGNIER, Olivier ROBINEAU, Olivier ROBINEAU, MD PhD, Reda CHIKOUCHE, Solange TREHOUX, PhD, Sophie PANAGET, Vincent DUBEE, Xavier LESCURE 2020-10-23
Dulce Digital-COVID Aware (DD-CA) Discharge Texting Platform for US/Mexico Border Hispanics With Diabetes + COVID-19 Coronavirus disease 19 infection, Non-insulin dependent diabetes Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Scripps Whittier Diabetes Institute National Institute of Diabetes, Digestive and Kidney Diseases US 2020-11-01 2021-08-31 3R01DK112322-05S1, 3R01DK112322-05S1, NCT04591015 Phase 3 Clinical Not yet recruiting 1 10 Months 172 Athena Philis-Tsimikas, MD 2020-10-22
The Effect of Clear Masks in Improving Patient Relationships Coronavirus disease 19 infection Transparent mask alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of North Carolina US 2020-09-03 2020-12-31 20-2229, NCT04595695 Phase Not Applicable Recruiting 1 3 Months 100 Ian Kratzke, MD, Ian M Kratzke, MD 2020-10-23
COVID-19-PE: Pulmonary Embolism and COVID-19 Coronavirus disease 19 infection, Lung embolism Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Usak University, Turkey Turkey 2020-03-01 2020-12-01 COVID-19-PE, NCT04590378, UU-PE001 Phase Not Applicable Recruiting 1 9 Months 600 Barış Sevinç, M.D., Canan Akkus, M.D., Cevdet Duran, M.D., Cevdet Duran, Prof., Hakan Yilmaz, M.D. 2020-10-22
Safety and Efficacy of Hydroxychloroquine for the Treatment and Prevention of Coronavirus Disease 2019 (COVID-19) Caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Coronavirus disease 19 infection, Injury elderberry intake alone, Variable regimens including N-acetylcysteine , azithromycin , hydroxychloroquine , quercetin , vitamin C , vitamin D3 , zinc Healthy volunteers accepted International Brain Research Foundation Inc US 2020-11-30 2021-12-31 CTP-HCQ-COVID19, NCT04590274 Phase 1 Clinical Not yet recruiting 1 13 Months 5000 Philip DeFina, PhD 2020-10-24
COVID-RASi: The COVID-RASi Trial (COVID-19) Cardiovascular disease, Coronavirus disease 19 infection Angiotensin II Receptor Blockers alone, Angiotensin converting enzyme inhibitor alone, renin-angiotensin system inhibitors alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ottawa Heart Institute Research Corp Canada 2020-10-30 2022-08-31 COVID-RASi, CTO-3212, NCT04591210 Phase 3 Clinical Not yet recruiting 1 22 Months 1155 Ermina Moga, Peter Liu, MD 2020-10-22
COVID-19 and Lung Ultrasound Utility Coronavirus disease 19 infection Butterfly iQ system alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Canada 2020-09-15 2021-09-30 0001, NCT04591158 Phase Not Applicable Recruiting 1 12 Months 100 William Cherniak, MD, MPH 2020-10-22
Remotely Delivered Programs Targeting COVID-19 Stress-Related Depression and Substance Use Acute stress disorder, Alcoholism, Anxiety disorder, Coronavirus disease 19 infection, Depression, Drug dependence CHAMindWell alone, Internet Cognitive Behavioral Therapy alone, Mindfulness Based Cognitive Therapy for Resilience During COVID-19 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Cambridge Health Alliance National Center for Complementary and Integrative Health, Pennsylvania State University US 2020-11-01 2022-11-01 3R33AT010125-03S1, CHA-IRB-1141/05/20, NCT04595084 Phase Not Applicable Not yet recruiting 1 24 Months 240 Carl Fulwiler, MD, Farah Samawi, Gabriella Conversano, Zev Schuman-Olivier, MD 2020-10-23
Maternal Telemental Health Interventions in Response to Covid-19*(CoronaVirus) Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression, Phobia Low-Intensity Psychosocial Interventions through Telemental health alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Hamad Medical Corp Qatar 2020-11-30 2022-02-28 MRC-05-087, NCT04594525 Phase Not Applicable Not yet recruiting 1 15 Months 58 2020-10-22
COVID-19 Burnout Study Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection Mindfulness Based Intervention alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Health Network Toronto 2020-11-01 2021-07-01 20-5678, NCT04594278 Phase Not Applicable Not yet recruiting 0 8 Months 100 2020-10-22
VGV: A 3-month Cycle of Virtual Guided Tours to Promote Health in Older Community Members in a Context of COVID-19 Induced Social Isolation: a Pilot Study Coronavirus disease 19 infection, Muscle weakness Museum virtual guided tours alone Healthy volunteers accepted, Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sir Mortimer B Davis Jewish General Hospital Canada 2021-01-04 2021-07-04 2021-2604, NCT04593433, VGV Phase Not Applicable Not yet recruiting 1 6 Months 40 Olivier Beauchet, MD 2020-10-27
GLS-1027 for the Prevention of Severe Pneumonitis Caused by SARS-CoV-2 Infection Coronavirus disease 19 infection, Viral pneumonia GLS-1027 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) GeneOne Life Science Inc 2020-11-30 2021-11-30 GLS27-005, NCT04590547 Phase 2 Clinical Not yet recruiting 0 12 Months 132 Medical Monitor, Project Manager 2020-10-22
PRISM: COVID-19: Pediatric Research Immune Network on SARS-CoV-2 and MIS-C Coronavirus disease 19 infection, Inflammatory disease Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) National Institute of Allergy and Infectious Diseases Autoimmunity Centers of Excellence US 2020-10-31 2022-04-30 DAIT PRISM-01, NCT04588363, NIAID CRMS ID#: 38772, PRISM Phase Not Applicable Not yet recruiting 21 18 Months 250 Charles E. Canter, MD, Ekemini Akan Ogbu, MBBS, MSc, Emily Wasserman, MD, MS, Hayley Gans, MD, James B. Schneider, MD, James D. Wilkinson, MD, MPH, Joseph Rossano, MD,MS,FAAP,FACC, Karen P. Acker, MD, Lara A. Danziger-Isakov, MD, MPH, Leigh M. Howard, MD, MPH, Lisa F. Imundo, MD, Maria T. Thanjan, MD, Marian G. Michaels,, MD, MPH, Moshe Arditi, MD, Nadine F. Choueiter, MD, Natasha B Halasa, MD, MPH, Natasha Ruth, MD, MS, Octavio Ramilo, MD, Paul F. Kantor, MBBCh,MSc,FRCPC, Pramod Narula, MD, Rakesh Singh, MD, Rana Chakraborty, MD, DPhil, Steven A. Webber, MBChB, MRCP, William T. Mahle, MD 2020-10-23
This is a Phase I Clinical Trial to Evaluate the Safety, Pharmacokinetics, and Immunogenicity of ADM-03820, a Monoclonal Antibody Cocktail Being Tested for the Treatment and Prevention of COVID-19 Coronavirus disease 19 infection SARS-CoV-2 monoclonal antibodies (COVID-19), Ology/ VUMC alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Ology Bioservices Inc US 2020-11-16 2021-08-30 ADM03820-001, NCT04592549 Phase 1 Clinical Not yet recruiting 2 9 Months 40 Angie Kimbler, Cassandra C Key, MD, Jonathan P Wilson, DO 2020-10-22
Study to Evaluate the Safety, Tolerability and Immunogenicity of an RNA Vaccine Candidate Against COVID-19 in Healthy Japanese Adults Coronavirus disease 19 infection BNT-162b2 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Japanese Ancestry BioNTech SE Pfizer Inc Japan 2020-10-20 2021-11-30 C4591005, NCT04588480 Phase 1/Phase 2 Clinical Recruiting 2 13 Months 160 Pfizer CT.gov Call Center 2020-10-22
Measurement of IL-6 and Secondary Inflammatory Markers Before and After Therapeutic Plasma Exchange (TPE) in Hospitalized Patients Acute lung injury, Coronavirus disease 19 infection, Respiratory distress syndrome therapeutic plasma exchange alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Larkin Community Hospital US 2020-09-11 2021-08-30 LCH-1-092020, NCT04592705 Phase 1 Clinical Recruiting 1 11 Months 10 Michael Talalaev, D.O. 2020-10-29
To Evaluate the Safety, Tolerability and Pharmacokinetic Properties of DWRX-2003 Coronavirus disease 19 infection repositioned niclosamide (refractory lung disease/COVID-19), Daewoong Pharmaceutical/Institut Pasteur Korea alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Daewoong Pharmaceutical Co Ltd Novotech (Australia) Pty Ltd 2020-10-19 2021-06-30 DW_DWJ1516101_AUSTRALIA, NCT04592835 Phase 1 Clinical Not yet recruiting 0 8 Months 24 2020-10-23
Effectiveness of Ivermectin and Doxycycline on COVID-19 Patients Coronavirus disease 19 infection Mechanical ventilation alone, Oxygen therapy/ C-Pap alone, Variable regimens including Vitamin C , Vitamin D3 , Zinc , acetaminophen , azithromycin , dexamethasone , doxycycline (Doxycin) , ivermectin , methylprednisolone Chloride channel modulator Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Alkarkh Health Directorate-Baghdad Iraq 2020-07-01 2020-10-14 IVM-DOX, NCT04591600 Phase 1/Phase 2 Clinical Completed 1 3 Months 140 Ahmed Sahib Abdulamir 2020-10-22
Study of Multiple Candidate Agents for the Treatment of COVID-19 in Hospitalized Patients Coronavirus disease 19 infection Standard of care alone, apremilast alone PDE 4 inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Amgen Inc 2020-10-26 2021-07-13 2020-002594-10, COV-01, NCT04590586 Phase 3 Clinical Not yet recruiting 0 8 Months 700 Amgen Call Center 2020-10-21
Seroprevalence of SARS CoV-2 infections/Covid-19 in blood donors and patients of the University Hospitals in Leipzig Coronavirus disease 19 infection Institut für Virologie, Universitätsklinikum Leipzig Germany 2020-06-20 147/20-ek, DRKS00023364 Phase Not Applicable Recruiting 1 2000 Christian Jassoy 2020-10-21
Evaluation the effect of virtual pulmonary rehabilitaion on covid 19 patients Coronavirus disease 19 infection Breathing exercise alone, Virtual pulmonary rehabilitation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Shiraz University of Medical Sciences Iran 2020-10-20 IR.SUMS.MED.REC.1399.364, IRCT20200930048892N1 Phase Not Applicable Recruiting 3 70 Abbas Rezaeian zade, Fariba Erfani, Parnian Nikmanesh, Seyed Mohammad Kazem Tadayyon, Seyed Rouhollah Mousavi 2020-10-21
Abdominal CT scan findings in patients with COVID-19 Coronavirus disease 19 infection abdominal CT scan alone Philippine General Hospital Philippines 2020-08-15 2020-09-18 PHRR201015-003026 PHRR201015-003026 Phase Not Applicable Completed 1 1 Month Gerard Eastdon Truadio D. Ochoco, MD 2020-10-21
SPARCOL: SuPAR in Adult Patients With COVID-19 Coronavirus disease 19 infection ELISA assay alone, suPARnostic kit (ViroGates) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Thessaly Greece 2020-10-11 2020-12-10 NCT04590794, SPARCOL, UTHDA-AC03 Phase Not Applicable Recruiting 1 2 Months 500 Athanasios Chalkias, PhD, Barbara Boutsis, Mrs, Eleni Laou, PhD 2020-10-24
CoV-Early: Early Convalescent Plasma Therapy for High-risk Patients With COVID-19 in Primary Care Coronavirus disease 19 infection convalescent plasma alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Erasmus University Medical Center Rotterdam Leiden University Medical Center, Sanquin Plasma Products B.V., The Netherlands Organisation for Health Research and Development Netherlands 2020-10-12 2023-11-01 CoV-Early, NCT04589949, NL74972.078.20 Phase 3 Clinical Recruiting 11 36 Months 690 Arvind Gharbharan, MD, Bart Rijnders, MD, PhD, Carlijn Jordans, MD, Casper Rokx, MD, PhD, D. Postma, MD, PhD, E. Jong, MD, PhD, Elana van Leeuwen, MD, PhD, Faiz Karim, MD, PhD, I Ludwig, MD, JJ Zwaginga, MD/PhD, L. Kampschreur, MD, PhD, R.W. van Etten, MD, PhD, Robert-Jan Hassing, MD, PhD, Robin Soetekouw, MD 2020-10-21
Development of a risk prediction model for people with diabetes and COVID-19 in Scotland Coronavirus disease 19 infection, Diabetes mellitus risk prediction model alone UK 2020-04-06 2020-07-31 ISRCTN45562523, PBPP REF. 1617- 0147 Phase Not Applicable Completed 1 3 Months 5782649 Prof Colhoun 2020-10-22
COVID-19-DM2: The Effect of Diabetes Mellitus on the Prognosis of Patients With COVID-19 Coronavirus disease 19 infection, Diabetes mellitus Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Usak University, Turkey Turkey 2020-03-20 2020-11-01 COVID-19-DM2, NCT04591704, UU-DM003 Phase Not Applicable Recruiting 1 7 Months 2000 Cevdet Duran 2020-10-21
Evaluation of the effect of Tofacitinib in COVID-19 patients Coronavirus disease 19 infection Rhofanib (Alvand Nanotechnology Company) alone Iran University of Medical Sciences Iran 2020-08-21 IR.IUMS.FMD.REC.1399.329, IRCT20200531047619N1 Phase 3 Clinical Recruiting 1 10 Seyed Abbas Motavalian, Simin Almasi 2020-10-21
ICE-COVID: Iota-carrageenan Nasal Spray COVID-19 Prophylaxis for Healthcare Professionals Coronavirus disease 19 infection Coldamaris plus iota-carrageenan (intranasal, H1N1 influenza), Marinomed Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Swansea University, Wales Abertawe Bro Morgannwg University Health Board, Cardiff University, Marinomed Biotechnologie GmbH, Walgreens Boots Alliance Inc UK 2020-12-20 2021-12-01 283187, ICE-COVID, NCT04590365 Phase 3 Clinical Not yet recruiting 1 11 Months 480 Iain S Whitaker, PhD FRCS, Zita M Jessop, MBBChir PhD 2020-10-22
FLAVOCOV Distributed Clinical Trial- COVID-19 Coronavirus disease 19 infection flavonoids alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kenya Medical Research Institute Kenya 2020-11-01 2021-01-31 PACTR202010537777617 Phase Not Applicable Not yet recruiting 1 3 Months 200 Leah Kigondu, Rick Sheridan, Willie Nyambati 2020-10-21
COREADOM: French Cohort of COVID-19 Patients With Post-intensive Care Syndrome Coronavirus disease 19 infection Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-10-15 2021-09-15 APHP200812, COREADOM, NCT04590170 Phase Not Applicable Not yet recruiting 1 11 Months 50 Camille : Camille, MD, Camille Camille, MD, Marie Benhammani-Godard, Marie-Martine Marie-Martine, MD, PhD 2020-10-21
VISION-Acute: The VISION-Acute Study Coronavirus disease 19 infection, Hypertension, Hypotension, Hypoxia, Respiratory disease Lifelight data collect app (Xim Ltd) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Xim Ltd Portsmouth Hospitals UK 2020-10-31 2021-01-31 NCT04589923, PHT/2020/50, VISION-Acute Phase Not Applicable Not yet recruiting 1 3 Months 200 Laura Wiffen 2020-10-20
Allocetra-OTS in COVID-19, Phase II Coronavirus disease 19 infection, Multiple organ failure, Respiratory disease, Respiratory failure, Septic shock standard of care therapy alone, Allocetra plus Ringer's lactate solution Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hadassah Medical Organization Barzilai medical center, Tel Aviv Sourasky Medical Center Israel 2020-05-07 2021-03-31 DM004, NCT04590053 Phase 2 Clinical Recruiting 3 10 Months 24 Dror Mevorach, MD, Peter V van Heerden, MD, Ronen Ben-Ami, Prof., Shlomo L Maayan, Prof. 2020-10-29
Levamizole in treatment of COVID-19 Coronavirus disease 19 infection levamisole alone, standard therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Isfahan University of medical Sciences Iran 2020-10-22 IR.MUI.MED.REC.1399.246, IRCT20181208041886N1 Phase 2 Clinical Recruiting 1 60 Dr. Shaghayegh Haghjoo, Morteza Pourahmad 2020-10-22
COVID-19 biomarker: Identification of biomarkers for prognosis of morbidity and mortality of SARS-CoV-2 (COVID-19) patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Munster Germany 2020-04-09 AZ 2020-210-f-S, COVID-19 biomarker, DRKS00023322 Phase Not Applicable Recruiting 1 100 Phil-Robin Tepasse 2020-10-21
A Clinical Trial of a Plasmid DNA Vaccine for COVID-19 (Covigenix VAX-001) in Adults Coronavirus disease 19 infection SARS-CoV-2 DNA vaccine (COVID-19), Entos/ Epivax alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Entos Pharmaceuticals Inc Canadian Center for Vaccinology, Canadian Institutes of Health Research, National Research Council of Canada Canada 2020-11-30 2021-06-30 ENTVAX01-101, NCT04591184 Phase 1/Phase 2 Clinical Not yet recruiting 1 7 Months 72 Gregory Reid, M.Sc, MBA, Sally Jones, Scott A. Halperin, M.D. 2020-10-27
Anhydrous Enol-Oxaloacetate (AEO) on Improving Fatigue in Post-COVID-19 Survivors Coronavirus disease 19 infection, Fatigue anhydrous enol-oxaloacetate (Terra Biological LLC) alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Terra Biological LLC US 2020-10-15 2021-06-15 NCT04592354, TB-AEO-2020 POST COVID FATIGUE Phase Not Applicable Recruiting 1 8 Months 40 Alan B Cash, MS, Lisa Tully, Ph.D. 2020-10-21
A prospective study to evaluate the accuracy of the Cue COVID-19 Test in patients Coronavirus disease 19 infection Cue COVID-19 Test alone Mayo Clinic Foundation Phase Not Applicable Status not specified 0 2020-10-20
A phase I/II clinical study to assess MRT-5500 in the treatment of subjects with SARS-CoV-2 infection Coronavirus disease 19 infection SARS-CoV-2 mRNA vaccine (COVID-19), Sanofi Pasteur/ Translate Bio alone Sanofi SA 2020-12-31 Phase 1/Phase 2 Clinical Planned 0 2020-10-20
A clinical trial to evaluate the efficacy of erdosteine in the treatment of hospitalized patients with COVID-19 infection with severe respiratory failure Coronavirus disease 19 infection, Respiratory failure erdosteine alone Elastase inhibitor Recipharm AB Italy Phase 2 Clinical Status not specified 1 20 2020-10-20
AERATOR: Studying aerosol emission of the COVID-19 virus in healthcare settings Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) North Bristol NHS Trust National Institute for Health Research (NIHR), United Kingdom Research & Innovation UK 2020-09-19 2021-09-19 3.4, IRAS 288784, CPMS 47097, AERATOR, ISRCTN21447815 Phase Not Applicable Recruiting 2 12 Months 600 Dr Fergus Hamilton 2020-10-22
Experience In Managing Special Groups Of Person Under Surveillance In Kelantan Coronavirus disease 19 infection Ministry of Health, Malaysia Malaysia 2020-10-18 2021-10-05 56079, NMRR-20-2238-56079 Phase Not Applicable Status not specified 1 11 Months Dr Farah Munirah Binti Mior Mazlan, dr NIK AIDA BT NIK ADIB 2020-10-20
Treatment of Covid-19 Using Infrared and/or Vitamin C Coronavirus disease 19 infection Infrared sauna therapy alone, vitamin C alone Healthy volunteers accepted GAAD Medical Research Institute Inc Canada 2020-10-30 2021-07-10 GAADMRI, NCT04584437 Phase Not Applicable Not yet recruiting 1 8 Months 400 Dr. Kwasi D Donyina, PhD, Yaa A Donyina, MDE 2020-10-27
A multicenter, clinical trial to validate the effectiveness of the Monocyte Distribution Width (MDW) hematology biomarker in the rapid detection of Multisystem Inflammatory Syndrome in Children (MIS-C) following SARS-CoV-2 infection Coronavirus disease 19 infection, Inflammatory disease Beckman Coulter Diagnostics Biomedical Advanced Research and Development Authority (BARDA), Johns Hopkins University School of Medicine, Massachusetts General Hospital, University of Florida US Phase Not Applicable Planned 3 Lael Yonker, M.D 2020-10-20
Secondary attack rate of COVID-19 and risk factors for transmission Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sri Ramachandra Institute of Higher Education and Research India 2020-10-16 CTRI/2020/10/028439 Phase Not Applicable Not yet recruiting 1 100 Manisha Arthur 2020-10-20
Efficacy of daclatasvir + sofosbuvir in patients with severe acute respiratory syndrome coronavirus (SARS-COVID-19) Coronavirus disease 19 infection, Viral pneumonia daclatasvir/sofosbuvir (Danesh Pharmaceutical Development Company) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ahvaz University of Medical Sciences Ahvaz Jundishapur University of Medical Sciences Iran 2020-06-25 IR.AJUMS.REC.1399.300, IRCT20200816048422N1 Phase 1/Phase 2 Clinical No longer recruiting 1 70 Dr Fatemeh Ahmadi, Dr. Fatemeh Ahmadi, Dr. Mohammad Badawi, Dr. Zahra Fakhraei 2020-10-20
PRECISION: An observational PRECISION study , to examine the immune responses to COVID-19 in healthy volunteers who have recovered from COVID-19 or were asymptomatic Coronavirus disease 19 infection Columbia University, Tonix Pharmaceuticals Holding Corp US PRECISION, TNX-C002 Phase Not Applicable Recruiting 1 Dr. Ilya Trakht, Dr. Sergei Rudchenko, Ph.D 2020-10-19
Effect of Ayurvedic Treatment Regimen in COVID-19 Patients Coronavirus disease 19 infection Variable regimens including Bilwadi Yog , Kantakaryavaleha , Shadangodak Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ministry of Ayush India 2020-11-02 CTRI/2020/10/028437 Phase 3 Clinical Not yet recruiting 3 380 Dr Leena Badgujar, Dr Milind B Nikumbh, Dr Shoeb Shaikh 2020-10-21
A trial to evaluate FX-06 in severe cases of COVID-19 Coronavirus disease 19 infection FX-06 alone Cadherin-5 modulator, Factor Ia modulator F4 Pharma GmbH Europe Phase Not Applicable Planned 0 2020-10-19
Perspective of cancer patient in COVID-19 pandemic Cancer, Coronavirus disease 19 infection chemotherapy alone, radiotherapy alone, systemic therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Indira Gandhi Medical College India 2020-12-01 CTRI/2020/10/028438 Phase 3 Clinical Not yet recruiting 1 1000 Shabnum Thakur 2020-10-21
A trial to evaluate stem cell therapy as a treatment for acute symptoms of COVID-19 Coronavirus disease 19 infection stem cell therapy alone BioXcellerator US Phase Not Applicable Not yet recruiting 1 2020-10-19
This study is designed to look at certain blood parameters like biomarkers for predicting the outcome of COVID patients Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) St Johns Medical College India 2020-10-25 CTRI/2020/10/028436 Phase Not Applicable Not yet recruiting 1 130 Dr Amarja Havaldar 2020-10-20
A phase III trial to evaluate post-exposure prophylaxis and pre-emptive treatment of AZD-7442 in covid-19 patients Coronavirus disease 19 infection AZD-7442 alone COVID19 Spike glycoprotein inhibitor AstraZeneca plc Biomedical Advanced Research and Development Authority (BARDA) US Phase 3 Clinical Planned 1 1100 2020-10-23
A phase III trial to evaluate the safety and efficacy of AZD7442 to prevention of COVID-19 Coronavirus disease 19 infection AZD-7442 alone COVID19 Spike glycoprotein inhibitor AstraZeneca plc Biomedical Advanced Research and Development Authority (BARDA) US Phase 3 Clinical Planned 1 5000 2020-10-23
Mental health of COVID 19 patients during outbreak Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression RTPCR test  alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) All India Institute of Ayurveda India 2020-10-16 CTRI/2020/10/028432 Phase Not Applicable Not yet recruiting 1 400 Dr Shivakumar Harti 2020-10-20
CoMMinS: COVID-19 testing and infection control in schools Coronavirus disease 19 infection RNA PCR test alone, Saliva-based antibody test alone, Viral RNA genome sequencing alone University of Bristol Medical Research Council UK 2020-09-01 2021-08-31 CoMMinS, IRAS 290071, ISRCTN82901740 Phase Not Applicable Not yet recruiting 1 12 Months 5000 Prof Caroline Relton 2020-10-20
A phase III clinical trial of Sputnik V for the potential prevention of COVID-19 infection Coronavirus disease 19 infection Sputnik V alone COVID19 Spike glycoprotein modulator Gamalei Institute of Epidemiology and Microbiology Philippines Phase 3 Clinical Recruiting 1 2020-10-19
A phase III clinical trial of Sputnik V for the potential prevention of COVID-19 infection Coronavirus disease 19 infection Sputnik V alone COVID19 Spike glycoprotein modulator Gamalei Institute of Epidemiology and Microbiology Saudi Arabia, United Arab Emirates 2020-10-13 Phase 3 Clinical Recruiting 2 2020-10-19
A clinical trial of ASLAN-003 for the treatment of Covid-19 and other viral infections Coronavirus disease 19 infection, Viral infection ASLAN-003 alone Dihydroorotate dehydrogenase inhibitor, p53 tumor suppressor protein stimulator ASLAN Pharmaceuticals Pte Ltd Phase Not Applicable Planned 0 2020-10-26
Cohort survey of healthcare workers with COVID-19 infection Coronavirus disease 19 infection Healthy volunteers accepted Chiba University Graduate School of Medicine Japan 2020-05-19 2020-06-11 UMIN000042142 Phase Not Applicable Completed 1 103 Taka-aki Nakada, Takeo Kurita 2020-10-21
An observational, case report to determine the diagnosis and management of upper gastrointestinal bleeding caused by SARS-CoV-2 infection during hospitalization Coronavirus disease 19 infection, Gastrointestinal bleeding Yunnan white drugs alone, gastroscopy alone, Variable regimens including aluminum phosphate , esomeprazole , octreotide acetate , thrombin Factor IIa agonist, H+ K+ ATPase inhibitor, Somatostatin receptor agonist Sun Yat-Sen University Phase Not Applicable Status not specified 0 1 2020-10-21
Evaluation of Respiratory profile and radiological changes in patients after recovery from COVID-19 Coronavirus disease 19 infection nintedanib alone, pirfenidone alone CSF-1 antagonist, FGF receptor antagonist, FGF1 receptor antagonist, FGF2 receptor antagonist, FGF3 receptor antagonist, Flt3 tyrosine kinase inhibitor, Lck tyrosine kinase inhibitor, Lyn tyrosine kinase inhibitor, PDGF receptor alpha antagonist, PDGF receptor antagonist, PDGF receptor beta antagonist, Src tyrosine kinase inhibitor, TGF beta receptor antagonist, VEGF receptor antagonist, VEGF-1 receptor antagonist, VEGF-2 receptor antagonist, VEGF-3 receptor antagonist, p38 MAP kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences India 2020-10-22 CTRI/2020/10/028372 Phase 4 Clinical Not yet recruiting 1 500 Anant Mohan 2020-10-20
Experiences among nurses caring patients with COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Manipal Academy of Higher Education India 2020-10-30 CTRI/2020/10/028373 Phase Not Applicable Not yet recruiting 1 30 Dr Leena Sequira, SHALINI G NAYAK 2020-10-20
A Clinical Study to Evaluate the Safety and Efficacy of CoviTone in Mild to Moderate COVID patients Coronavirus disease 19 infection CoviTone alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) India 2020-10-22 CTRI/2020/10/028376 Phase 2 Clinical Not yet recruiting 1 80 Dr M E Mohan, Jestin V Thomas 2020-10-20
KluT: COVID-19 Cluster in Temerloh: Is it related to tabligh? Coronavirus disease 19 infection 2020-10-13 2021-02-08 55897, KluT, NMRR-20-2208-55897 Phase Not Applicable Recruiting 0 3 Months Dr. Safaridah binti Anuar 2020-10-20
PVAS COVID-19: COVID-19: Public Awareness, Perception and Impact on Pharmacy Value Added Services (PVAS) in Kedah, Malaysia Coronavirus disease 19 infection Malaysia 2020-10-15 2021-06-30 55892, NMRR-20-2195-55892, PVAS COVID-19 Phase Not Applicable Not yet recruiting 1 8 Months Mrs Nurliana Binti Abdul Latif, norazila bt abdul ghani 2020-10-19
Effect of remdesivir in COVID-19 Coronavirus disease 19 infection remdesivir alone COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ahvaz University of Medical Sciences Iran 2020-09-27 IR.AJUMS.REC.1399.407, IRCT20200404046937N5 Phase 2/Phase 3 Clinical No longer recruiting 2 50 Dr Fatemeh Ahmadi, Mehdi Ahmadi Moghadam, Mehran Varnaseri, Mehran Varnasseri, Roohangiz Nashibi 2020-10-27
Cope-Corona: Identifying and strengthening personal resources to cope with the corona pandemic Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression, Psychiatric disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tongji Hospital China 2020-08-01 2023-07-31 ChiCTR2000038929, Cope-Corona Phase Not Applicable Not yet recruiting 1 36 Months 600 Heng Wu, Zheng Lu 2020-10-19
COVADIS study: COVID-19 Epidemic in West Africa (WA): infection dynamics and diagnostic approaches Coronavirus disease 19 infection COVID test kit alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Medical Research Council Unit, The Gambia European and Developing Countries Clinical Trials Partnership Gambia 2020-10-12 COVADIS study, PACTR202010472402152 Phase Not Applicable No longer recruiting 1 1100 Annette Erhart, Bakary Conteh, Vivat Thomas Njie 2020-10-19
ANTICOV IMMUNO: The impact of COVID-19 treatment on the type, strength and duration of antibody and cellular immune responses in SARS-CoV-2 patients in sub-Saharan Africa Ancillary Study of the ANTICOV Study: An open-label, multicentre, randomised, adaptive platform trial of the safety and efficacy of several therapies, including antiviral therapies, versus control in mild / moderate cases of COVID-19 Coronavirus disease 19 infection hydroxychloroquine alone, lopinavir + ritonavir alone HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bernhard-Nocht-Institute for Tropical Medicine, Drugs for Neglected Diseases Initiative, Ifakara Health Institute, Institute of Tropical Medicine Egypt 2020-09-21 ANTICOV IMMUNO, PACTR202010781639956 Phase Not Applicable Recruiting 1 1000 Gemma Moncunill, James Arkinstall, Nathalie StrubWourgaft 2020-10-20
A clinical trial to evaluate the efficacy of polyvalent highdosage intravenous immunoglobulin to stabilize or improve the health of COVID-19 patients Coronavirus disease 19 infection polyvalent high-dosage intravenous immunoglobulin alone Grifols SA Spain Phase Not Applicable Planned 1 2020-10-19
KoCo19-CED-1: Clinical care situation, health problems and psychosocial burdens during the COVID-19-pandemic in patients with chronic inflammatory bowel disease (IBD) - Part 1: Baseline survey and seroprevalence of SARS-CoV-2 antibodies compared to Munich population cohort (KoCo19) Coronavirus disease 19 infection, Inflammatory bowel disease blood test alone Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Klinikum der Universitat Muenchen Germany 2020-07-04 20-523, DRKS00021698, DRKS00022155, KoCo19-CED-1 Phase Not Applicable Recruiting 2 400 Elisabeth Klucker, Leandra Koletzko, Sibylle Koletzko, Simone Breiteneicher, Tobias Schwerd 2020-10-20
PRASACT: Clinical study to evaluate the effect of Ayurveda intervention as a prophylaxis for COVID-19 in Healthcare workers Coronavirus disease 19 infection Variable regimens including Amritotaram Kashayam Prakshepa , Chywanaprasha , Dasamoola Katutrayam Kashayam , Dhanvantaram Gutika , GuduchyAdi Kashayam Prakshepa , Haridrakhandam , Indukantam Kashayam , Nayopayam KS Prakshepa , Sudarshana Ghana Vati , Vasaristam+Kanakasavam , VidAryAdi KS Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ministry of Ayush India 2020-10-30 CTRI/2020/10/028424, PRASACT Phase 3 Clinical Not yet recruiting 1 200 Dr Zankhana Buch 2020-10-19
A clinical study to see the effects and safety of PNB-001 in patients with moderate COVID-19 infection Coronavirus disease 19 infection PNB-001 alone, Standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Byramjee Jeejeebhoy Govt Medical College and Sassoon General Hospitals India 2020-10-28 BCR-PNB-001, CT/ND/95/2020, CTRI/2020/10/028423 Phase 2 Clinical Not yet recruiting 1 40 Dr Neeta Nargundkar, Dr Pradnya Bhalerao 2020-10-20
Effect of COVID-19 on lymphocyte and eosinophil count Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences Patna India 2020-10-24 CTRI/2020/10/028422 Phase Not Applicable Not yet recruiting 1 150 DR AMARJEET KUMAR 2020-10-21
The effect of synbiotic on inflammatory markers and clinical manifestations in patients with COVID-19 Coronavirus disease 19 infection Lactocar synbiotic alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Isfahan University of medical Sciences Iran 2020-10-22 IR.MUI.MED.REC.1399.204, IRCT20200923048815N1 Phase 2/Phase 3 Clinical Recruiting 1 80 Majid Aghadavood Marnani, Masha Khodadoostan Shahraki, Shaghayegh Haghjoy Javanmard 2020-10-22
SaNPS: Stress and neuropsychiatric symptoms/disorders (ie, functional brain diseases): COVID-19 as a source of stress Acute stress disorder, Coronavirus disease 19 infection group wellbeing therapy group wellbeing therapy alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Xuanwu Hospital Of Capital Medical University China 2020-01-04 2021-01-04 ChiCTR2000039079, SaNPS Phase Not Applicable Recruiting 1 12 Months 400 Hongxing Wang 2020-10-20
PAP SURVEY: A Survey of Psychological Distress and Its Associated Factors Among Health Service Providers Amidst the Covid-19 Pandemic in Malaysia Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression Healthy volunteers accepted Selayang Hospital Malaysia 2020-11-10 2020-12-16 56529, NMRR-20-2235-56529, PAP SURVEY Phase Not Applicable Status not specified 1 1 Month Dr Muhammad Haniff Bin Abdullah 2020-10-21
Persuasion in Medicine: Experimental Evidence on Sender and Signal Effects Coronavirus disease 19 infection Video about safety and effectiveness alone, direct messaging on COVID-19 vaccine safety and efficacy alone Healthy volunteers accepted, Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Harvard University Massachusetts Institute of Technology, Stanford University US 2019-12-20 2021-02-15 IRB19-1424, NCT04160975 Phase Not Applicable Recruiting 1 13 Months 3350 2020-10-19
Kap of New Normal among HCW's in Hospital Kuala Lumpur and Hospital Sungai Buloh Regarding Covid-19 Coronavirus disease 19 infection University of Malaya Malaysia 2020-11-01 2021-10-31 NMRR-20-2224-56820 Phase Not Applicable Status not specified 2 12 Months Dr Sri Viknarajan A/L Puvendran 2020-10-16
COVID19-MSK INJECTION Coronavirus disease 19 infection, Rheumatoid arthritis HOSPITAL QUEEN ELIZABETH II Malaysia 2020-10-31 2021-08-02 NMRR-20-2221-56202 Phase Not Applicable Status not specified 1 9 Months MOHAMAD AZWAN BIN AZIZ 2020-10-20
EDWH COVID-19 Coronavirus disease 19 infection Melaka Hospital Malaysia 2020-10-25 2020-12-31 NMRR-16-2910-29170 Phase Not Applicable Status not specified 5 2 Months Madam NOORHALIZA BT ALI 2020-10-20
A study to assess safety and efficacy of natural killer cells in the treatment of covid-19 Coronavirus disease 19 infection K-NK-ID101 alone Abigail Wexner Research Institute, Kiadis Pharma BV Phase Not Applicable Planned 0 2020-10-16
The COVID PROFILE study Coronavirus disease 19 infection Walter and Eliza Hall Institute of Medical Research Royal Melbourne Hospital, The Peter Doherty Institute for Infection and Immunity, University of Melbourne Phase Not Applicable Status not specified 0 300 Dr Vanessa Bryant, Professor Ivo Mueller 2020-10-16
NCoV-Radi: NCoV-Radi Coronavirus disease 19 infection chest radiography alone, computed tomography imaging alone The University of Hong Kong Hong Kong 2020-02-10 2021-01-31 HKUCTR-2850, NCoV-Radi, UW 20-115, v1 Phase Not Applicable Recruiting 1 11 Months 50 Dr. Ming-Yen Ng, HKUCTR Administrator 2020-10-19
ICARD: The impact of COVID-19 pandemic-related activity restriction on the outcomes of chronic obstructive lung disease Chronic obstructive pulmonary disease, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Nagoya University Nagoya University Graduate School of Medicine Japan 2020-09-01 2023-03-31 ICARD, UMIN000042106 Phase Not Applicable Recruiting 1 31 Months 150 Akira Ando, Naozumi Hashimoto 2020-10-20
A Phase I, Open-Label, Parallel-Group, Single-Dose Study to Evaluate the Pharmacokinetics of Remdesivir and Metabolites in Participants with Normal Renal Function and Renal Impairment Coronavirus disease 19 infection remdesivir alone COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Gilead Sciences Inc US, Australia, Puerto Rico, New Zealand, Germany 2020-11-02 ACTRN12620001048976p Phase 1 Clinical Not yet recruiting 5 80 Dr Christian Schwabe 2020-10-19
REMOTE CONTROL: Home-based blood pressure monitoring of Hypertensive Diseases in Pregnancy - A randomized, controlled trial Coronavirus disease 19 infection, Hypertension, Pre-eclampsia Home-based blood pressure monitoring -app alone, automated BP machine alone, education and training alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Campbelltown Hospital, Liverpool Hospital Heart Research Institute Ltd Australia 2021-01-01 ACTRN12620001049965p, REMOTE CONTROL Phase Not Applicable Not yet recruiting 1 300 Dr Theepika Rajkumar 2020-10-21
Extended SIR model Coronavirus disease 19 infection Clinical Research Centre 2020-10-14 2021-10-13 56878, NMRR-20-2217-56878, model01 Phase Not Applicable Status not specified 0 12 Months Pharmacist Law Kian Boon 2020-10-19
SERVQUAL Model in Hospital Coronavirus disease 19 infection health management alone Universiti Kebangsaan Malaysia Malaysia 2020-11-01 2021-03-31 54898, NMRR-20-2131-54898 Phase Not Applicable Not yet recruiting 34 5 Months Siti Nurfadhilah binti Arsad 2020-10-19
Clinical study of an Ayurveda formulation containing Gold and Indian Gooseberry along with Tulasi juice as an add on therapy in standard care of COVID 19 patients Coronavirus disease 19 infection Swarna Amalaki alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ministry of Ayush Acharya Vinoba Bhave Rural Hospital India 2020-11-02 CTRI/2020/10/028414 Phase 2 Clinical Not yet recruiting 0 60 Anjalee Chiwane, Jyothy K B 2020-10-20
Psychological responses of medical staff during COVID-19 and the adjustment effect of brief mindfulness meditation Coronavirus disease 19 infection brief mindfulness meditation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Naval Medical Research Institute of PLA National Natural Science Foundation of China China 2021-01-01 2021-12-31 ChiCTR2000039002 Phase 0 Clinical Not yet recruiting 1 12 Months 400 Liu Yunzi 2020-10-19
School teachers experience in online teaching during this COVID-19 situation Acute stress disorder, Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Manipal Academy of Higher Education India 2020-10-13 CTRI/2020/10/028412 Phase Not Applicable Not yet recruiting 1 200 JOSHUA RAYMOND ANDRADE, UMESH THONSE 2020-10-21
A Phase III clinical trial for inactivated novel coronavirus pneumonia (COVID-19) vaccine (Vero cells) Coronavirus disease 19 infection, Viral pneumonia COVID-19 vaccine (inactivated, Vero cells/intramuscular), Wuhan Institute of Biological Products/Wuhan Institute of Virology, CAS alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) China National Biotec Group, Wuhan Institute of Biological Products Co Ltd Morocco 2020-09-02 2020-12-31 ChiCTR2000039000 Phase 3 Clinical Recruiting 1 3 Months 600 Professeur Abouqal Redouane, Wei Chen 2020-10-23
A population based survey on COVID-19 infection in Goa state among both urban and rural population Coronavirus disease 19 infection Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Government of Goa India 2020-10-16 CTRI/2020/10/028384 Phase Not Applicable Not yet recruiting 1 1000 Dr Dhananjay Lad, Dr Vijaykumar Patil 2020-10-20
Clinical characteristics and laboratory parameters of COVID-19 patients on oxygen Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) National Cancer Institute, Jhajjar, AIIMS India 2020-10-20 CTRI/2020/10/028340 Phase Not Applicable Not yet recruiting 1 100 Dr Anuja Pandit 2020-10-20
To study the relationship between spirituality,hope, distress and ability to bounce back from stress among family members of recovered COVID-19 patients Acute stress disorder, Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Government Medical College and Hospital,Chandigarh India 2020-11-01 CTRI/2020/10/028339 Phase Not Applicable Not yet recruiting 1 30 Anushka Negi, Dr Ajeet Sidana, Dr Manoj Kumar 2020-10-19
The Provider Insurance Revenue Study in Healthcare Providers in the United States of America Coronavirus disease 19 infection University of California Irvine US 2020-10-01 2021-10-15 NCT04587245, PIRSTUDY Phase Not Applicable Recruiting 1 12 Months 100 Charles Bronson, Charles Bronson, MBA, Henry Broeska, Henry Broeska, PhD, Sheridan Merrick, BA 2020-10-21
NEUROCOV-19: Investigation of COVID-19 associated neurological comorbidities Coronavirus disease 19 infection, Neurological disease electrophysiological examination alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitatsklinikum Essen Germany 2020-10-25 20-9284-BO, DRKS00023312, NEUROCOV-19 Phase Not Applicable Recruiting 1 250 Mark Stettner, Michael Fleischer 2020-10-21
Dyhor-19: Diagnosis of Endocrine Dysfunctions in COVID-19 Coronavirus disease 19 infection, Endocrine disease Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Montpellier France 2020-03-01 2020-05-30 Dyhor-19, NCT04587375, RECHMPL20_0205 Phase Not Applicable Completed 1 2 Months 50 Philippe GUILPAIN, MD, PhD 2020-10-16
PROSPER: Pregnancy Outcomes During the Pandemic: Using Placental Pathology and Gene Expression to Understand Fetal Risk Coronavirus disease 19 infection Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Prisma Health-Upstate US 2020-08-04 2021-09-30 NCT04585945, PRO00101090, PROSPER Phase Not Applicable Recruiting 3 13 Months 100 Jessica Britt, PhD, Jessica L Britt, PhD 2020-10-16
Development and Use of a Post-COVID-19 Quality of Life Patient-reported Outcome Measure Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) UK 2020-10-07 2025-10-31 MED-ASST 33, NCT04586413 Phase 1/Phase 2 Clinical Recruiting 1 60 Months 100 Ravi Jandhyala, Rose Watson 2020-10-16
An observational study to determine the postdischarge venous thromboembolism rates following hospital admission with COVID-19 Coronavirus disease 19 infection, Thromboembolism venous thromboembolism analysis alone Kings College Hospital NHS Trust Phase Not Applicable Status not specified 0 2020-10-18
MySteps-CoV: eHealth Intervention on Physical Activity for Type 2 Diabetics - Frustrated by COVID-19 Coronavirus disease 19 infection, Non-insulin dependent diabetes ExSed app alone, Usual care alone, counselling contacts alone, eHealth alone, hip-worn accelerometer alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) UKK-instituutti North Karelia Central Hospital, University Of Eastern Finland Finland 2019-03-06 2020-10-31 MYSTEPS ETL 303/2017, MySteps-CoV, NCT04587414 Phase Not Applicable No longer recruiting 1 19 Months 122 Harri Sievanen, Tommi Vasankari, MD, PhD 2020-10-20
Improving the Mental Health of Resident Physicians and Fellows Through Transcendental Meditation Acute stress disorder, Coronavirus disease 19 infection Transcendental meditation alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Arizona US 2020-11-30 2021-12-31 2008969193, NCT04586309 Phase Not Applicable Not yet recruiting 1 13 Months 50 Alison Sutton-Ryan, LCSW, Rachel E M Cramton, MD 2020-10-19
Endothelial dysfunction in severe COVID-19 disease Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute Of Medical Sciences, Rishikesh India 2020-10-19 CTRI/2020/10/028361 Phase Not Applicable Not yet recruiting 1 40 Rohit Walia 2020-10-21
Psychiatric sequelae in COVID-19 infection recovered resident doctors and interns of a tertiary health care hospital Coronavirus disease 19 infection, Psychiatric disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Seth GS Medical College India 2020-10-19 CTRI/2020/10/028360 Phase Not Applicable Not yet recruiting 1 60 Dr Neena S Sawant 2020-10-16
MoxiCov: Feasibility and Impact of Remote Oximetry in Patients Hospitalized With COVID-19 Coronavirus disease 19 infection, Hypoxia Digital oximeter alone, cardiac frequency monitoring alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo Brazil 2020-06-22 2021-06-22 5058/20/087, MoxiCov, NCT04587921 Phase Not Applicable Recruiting 1 12 Months 90 Daniel Queiróz, PhD, Diego Prieto, Msc, Geraldo Lorenzi Filho, Geraldo Lorenzi, M.D. PhD, Luciano Drager, M.D. PhD, Pedro Genta, M.D PhD 2020-10-16
A clinical trial to evaluate the effectiveness and safety of Vedicinals-9- a Herbal formulation in mild to moderate COVID-19 patients Coronavirus disease 19 infection Vedicinals-9 alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) India 2020-10-19 CTRI/2020/10/028364, EPRD0202-010920 Phase 2 Clinical Not yet recruiting 2 124 Dr Govinda Narke, Dr Nitin Shinde, Yogendra Kumar Choudhary 2020-10-16
The barriers encountered by health-service providers while giving healthcare to patients admitted to COVID hospitals of Odisha Coronavirus disease 19 infection online self-administered questionnaire alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Kalinga Institute of Medical Sciences India 2020-11-01 CTRI/2020/10/028363 Phase Not Applicable Not yet recruiting 1 1000 Nipa Singh 2020-10-16
The Study of 'Gam-COVID-Vac' Vaccine Against COVID-19 With the Participation of Volunteers of >/= 60 years old Coronavirus disease 19 infection Sputnik V alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gamalei Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation Collaborator Russian Federation 2020-10-22 2020-12-31 05-GAM-COVID-VAC-2020, NCT04587219 Phase 2 Clinical Recruiting 1 2 Months 110 Inna Dolzhikova, PhD, Nikita Lomakin, MD, PhD 2020-10-28
Study to assess the efficacy of deep breathing Pranayama technique in addition to conventional allopathic treatment in management of COVID-19 Coronavirus disease 19 infection deep breathing Pranayama alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) India 2020-10-15 CTRI/2020/10/028362, JRH/IEC/2020/COVID19/Pranayama breathing technique Phase Not Applicable Not yet recruiting 1 278 Dr Anuja Santosh Kulkarni 2020-10-19
Improving Cancer Screening and Prevention During the COVID-19 Pandemic in Underserved Populations of Rhode Island Breast tumor, Colorectal tumor, Coronavirus disease 19 infection Cancer screening alone, Colonoscopy alone, Informational videos and social media campaign alone, Mammogram alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rhode Island Hospital US 2020-08-28 2022-09-01 1613494-3, NCT04587258 Phase Not Applicable Recruiting 1 24 Months 100 Cristina Pacheco, MD, Don Dizon, MD, Howard Safran, MD 2020-10-17
Study to Assess the Effect of Meplazumab on COVID-19 Coronavirus disease 19 infection meplazumab alone, standard of care alone Basigin inhibitor, COVID19 Spike glycoprotein inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Pacific Meinuoke Biopharmaceutical 2020-10-30 2021-04-30 MPZ-II-02, NCT04586153 Phase 2/Phase 3 Clinical Not yet recruiting 0 6 Months 456 Shuangshuang Liu, Xiaochun Chen 2020-10-16
ETHICOVID: Operation of the GHPSJ Clinical Ethical Reflection Assistance Group During the COVID-19 Period Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Groupe Hospitalier Paris Saint-Joseph France 2020-11-09 2022-04-30 ETHICOVID, ETHICOVID, NCT04586140 Phase Not Applicable Not yet recruiting 1 17 Months 30 Helene BEAUSSIER, PharmD, pHD, Marie-Lorraine de WARREN, Nurse 2020-10-16
CoCovSDRA: Effect of Corticosteroid Treatment on Prognosis in ARDS Secondary to Covid-19 Coronavirus disease 19 infection, Respiratory distress syndrome corticosteroid treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Hospital, Nancy, France France 2020-03-01 2020-12-31 2020PI109, CoCovSDRA, DUBOST_2020_PI_109, NCT04586114 Phase Not Applicable No longer recruiting 1 10 Months 200 Sebastien GIBOT 2020-10-20
A trial to evaluate ALF-1001 for the preventing the spread of COVID-19 Coronavirus disease 19 infection ALF-1001 alone IL-22 antagonist, IL-23 antagonist, Interferon alpha 14 ligand, Interleukin 17A ligand inhibitor, Interleukin 17F ligand inhibitor, TNF alpha ligand inhibitor ILC Therapeutics Ltd Phase Not Applicable Planned 0 2020-10-15
A phase III clinical trial to evaluate the efficacy of SARS-CoV-2 peptide vaccine (li-Key, COVID-19), Generex for the potential prevention of COVID-19 infection Coronavirus disease 19 infection SARS-CoV-2 peptide vaccine (li-Key, COVID-19), Generex alone Generex Biotechnology Corp Bintai Kinden Corp US Phase 3 Clinical Planned 1 2020-10-15
A case-control study of lenzilumab in patients with severe and critical COVID-19 Coronavirus disease 19 infection lenzilumab alone GM-CSF ligand inhibitor, Immunoglobulin G1 modulator, Immunoglobulin kappa modulator Humanigen Inc Phase Not Applicable Status not specified 0 39 2020-10-15
A patient case report to evaluate lenzilumab in severe and critical COVID-19 patient Coronavirus disease 19 infection lenzilumab alone GM-CSF ligand inhibitor, Immunoglobulin G1 modulator, Immunoglobulin kappa modulator Male, European Ancestry Humanigen Inc Phase Not Applicable Status not specified 0 2020-10-15
VEGF and sFlt-1 Levels in the Pathogenesis and Severity of COVID-19 Disease Cardiac failure, Cardiovascular disease, Coronavirus disease 19 infection, Multiple organ failure, Renal failure, Respiratory failure Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Alabama at Birmingham US 2020-05-22 2023-05-20 IRB-300005378, NCT04587323 Phase Not Applicable Recruiting 1 35 Months 100 Dylan Addis, MD, Shanna H Graves 2020-10-16
A clinical trial of TLC-19 for the treatment of COVID-19 Coronavirus disease 19 infection TLC-19 alone Healthy volunteers accepted Taiwan Liposome Co Australia, Taiwan Phase 1 Clinical Recruiting 2 30 2020-10-24
MOR: Mouth Rinses for Inactivation of COVID-19 Coronavirus disease 19 infection Betadine gargle alone, Colgate Optic White alone, Colgate Total mouthwash alone, Listerine alone, Peridex alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of North Carolina US 2020-10-31 2023-09-30 20-2040, MOR, NCT04584684 Phase 2 Clinical Not yet recruiting 1 35 Months 480 Laura Jacox, DMD, PhD, S.T. Phillips, Wendy Lamm 2020-10-16
Outcomes of and Prognosis Factors for COVID-19 Patients - An Observational Study Coronavirus disease 19 infection Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Xiangya Hospital Of Central South University China 2020-01-17 2021-02-28 ChiCTR2000038943 Phase Not Applicable Recruiting 1 13 Months 233 Suixin Liu, Yaoshan Dun 2020-10-16
Gynecological Laparoscopic Surgery during COVID-19 Pandemic Coronavirus disease 19 infection, Gynecological disorder Putrajaya Hospital Malaysia 2020-09-30 2020-10-30 NMRR-20-2129-56450 Phase Not Applicable Status not specified 1 1 Month Dr Raimi Zamriah Hasan, Dr Tunisha a/p Ganisakran 2020-10-16
Biochemistry and hematology sample handling during COVID-19: Hospital Sungai Uloh experience Coronavirus disease 19 infection Hospital Sungai Buloh Malaysia 2021-01-25 2021-01-27 56713, NMRR-20-2127-56713 Phase Not Applicable Status not specified 1 Dr NUR AMALINA BINTI YUSOFF, Dr Sharifah Khairul Atikah 2020-10-19
A large, pragmatic, open-label study to assess efficacy and safety of bamlanivimab monotherapy or combination therapy with etesevimab Coronavirus disease 19 infection bamlanivimab alone, bamlanivimab plus etesevimab COVID19 Spike glycoprotein modulator Eli Lilly & Co Phase Not Applicable Planned 0 2020-10-15
ACTIV-3: A clinical trial of bamlanivimab for the treatment of patients with ambulatory and hospitalized COVID-19 patients Coronavirus disease 19 infection bamlanivimab plus remdesivir COVID19 Spike glycoprotein modulator, COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Eli Lilly & Co, National Institutes of Health ACTIV-3 Phase Not Applicable Suspended 0 1000 2020-10-20
BLAZE-4: A clinical trial to evaluate IV doses of etesevimab in combination with bamlanivimab Coronavirus disease 19 infection bamlanivimab plus etesevimab COVID19 Spike glycoprotein inhibitor, COVID19 Spike glycoprotein modulator Eli Lilly & Co BLAZE-4 Phase Not Applicable Planned 0 2020-10-15
An observational study on the clinical characteristics of metastatic prostate cancer patients infected with COVID-19 in South Italy Coronavirus disease 19 infection, Hormone refractory prostate cancer, Metastatic prostate cancer LHRH agonist therapy alone, chemotherapy alone, enzalutamide alone, hormonal treatment alone Androgen receptor antagonist, Cytochrome P450 3A4 stimulator, DNA binding protein inhibitor, Prostate specific antigen modulator, Translocation associated protein inhibitor Male University of Molise Italy Phase Not Applicable Status not specified 1 2 2020-10-15
A Phase II Study of RTB-101 as COVID-19 Post-Exposure Prophylaxis in Older Adults Coronavirus disease 19 infection dactolisib alone Phosphoinositide 3-kinase inhibitor, mTOR complex 1 inhibitor, mTOR complex 2 inhibitor Aged Adults (65-79 yrs), Elderly Adults (80 and over) resTORbio Inc Harvard Medical School, National Institute on Aging, University of Connecticut Health Center US 2020-10-13 2021-02-28 3R01AG064802-02S1, NCT04584710, RTB101-211 Phase 2a Clinical Recruiting 2 4 Months 60 Lisa Kenyon-Pesce, Medical Monitor, Peggy Gagnon 2020-10-27
D-dimer Adjusted Versus Therapeutic Dose Low-molecular-weight Heparin in Patients With COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia D-dimer and weight adjusted therapy alone, enoxaparin sodium alone Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ain Shams University Egypt 2020-08-01 2020-12-31 FMASU P35/ 2020, NCT04584580 Phase 4 Clinical Recruiting 1 5 Months 50 Ashraf Madkour, Fatma Soliman E Ebeid 2020-10-16
OD-doxy-PNVCOV Old Drug 'DOXY' for Prevention of New Virus Virus OD-doxy-PNV Coronavirus disease 19 infection doxycycline plus zinc Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hopital Militaire Principal d'instruction de Tunis Dacima Consulting Tunisia 2020-10-30 2021-03-01 NCT04584567, UR17DN05 Phase 3 Clinical Not yet recruiting 1 4 Months 1100 Batikh R Riadh, physican, Ben Moussa M mohamed, physican, Ferjani M Mustapha, physican, Gharsallah H Hedi, physican, Mrabet A Ali, physican, Stambouli N nejla, phd, Youssfi MA Mohamed Al, physican 2020-10-15
The Effect of Aerobic Exercise on Immune Biomarkers and Symptoms Severity and Progression in Patients With COVID-19: A Pilot, Randomized, Control Trial Coronavirus disease 19 infection, Gastrointestinal disease, Upper respiratory tract infection, Viral pneumonia Moderate Intensity Aerobic Exercises alone, aerobic exercise alone, hydroxyclorocin sulphate (Plaquenil) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Turkey 2020-01-01 2020-10-01 AEROBIC EXERCISE, COVID-19, NCT04581291 Phase Not Applicable Completed 1 9 Months 30 Motaz Alawna 2020-10-15
LIFTCOVID: Lift Mobile Mindfulness for COVID-19 Distress Symptoms Coronavirus disease 19 infection, Depression, Generalized anxiety disorder, Respiratory distress syndrome Lift mobile mindfulness program app alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Duke University National Center for Complementary and Integrative Health US 2020-11-01 2021-09-30 3U01AT009974-03S1, LIFTCOVID, NCT04581200, PRO00106306 Phase Not Applicable Not yet recruiting 4 11 Months 300 Allie Frear, Catherine L Hough, MD, MSc, Christopher Cox, MD, Christopher E Cox, MD, Jeffrey McKeehan, Lee Kamphuis, MPH, Madeleine McDougal, Marc Moss, MD, Theodore Iwashyna, MD, PhD 2020-10-16
SYNBIOTIC COV STUDY: An Evaluation of a Synbiotic Formula for Patients With COVID-19 Infection Coronavirus disease 19 infection health supplements (Synbiotic) alone, standard care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chinese University of Hong Kong Hong Kong 2020-08-13 2022-04-30 NCT04581018, SYNBIOTIC COV STUDY, SYNBIOTIC COV STUDY Phase Not Applicable Recruiting 1 20 Months 50 Amy Li, Kitty Cheung, Siew Chien Ng, Siew Chien Ng, PhD 2020-10-16
Clinical trail of remdesivir in Covid-19 patinets Coronavirus disease 19 infection, Viral pneumonia remdesivir alone COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hungary 2020-10-12 2020-004928-42, REM-ENY-01 Phase 3 Clinical Recruiting 1 2000 CRO 2020-10-16
DYADS: Dysphagia and Dysphonia Outcomes in SARS CoV-2 (COVID-19) Infection Coronavirus disease 19 infection, Dysphagia, Dysphonia fiberoptic endoscopic evaluation of swallowing test alone, videofluoroscopy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cambridge University Hospitals NHS Foundation Trust UK 2020-09-15 2021-12-31 20/NW/0333, DYADS, NCT04584658 Phase Not Applicable Recruiting 1 15 Months 36 Andrie Schembri, BSc, Brian Fish, FRCS (ORL-HNS), Claudia Russell, MSc, Ekpemi Irune, Ekpemi Irune, FRCS (ORL-HNS), Liam Masterson, FRCS (ORL-HNS), Rachel Kyd, Sarah Pilsworth, MSc 2020-10-20
Patterns of Arrhythmias and Conduction Block in COVID-19 Patients and Its Relation to Myocardial Injury Detected by Cardiac Magnetic Resonance Atrioventricular block, Coronavirus disease 19 infection, Heart arrhythmia, Heart injury SSFP sequence based cine imaging alone, cardiac magnetic resonance imaging alone, gadolinium alone, myocardial perfusion imaging alone, tissue characterization imaging alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assiut University Egypt 2020-11-01 2024-01-01 ARRHYTHMIAS IN COVID-19, NCT04584411 Phase Not Applicable Not yet recruiting 1 38 Months 50 Ahmed AR Hassaan, bachelor, Alaa A El-Moniem, Doctorate, Doaa A Fouad, Doctorate, Maram M Shafiq, student, Mohamed A.H Abdelhafez, Doctorate, Shimaa S Khider, Doctorate 2020-10-15
Ain Shams University Experience: Clinical Determinants of Hospitalized COVID-19 Patients Coronavirus disease 19 infection laboratory test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ain Shams University Egypt 2020-06-27 2020-12-30 FMASU P30/ 2020, NCT04584606 Phase Not Applicable Recruiting 1 6 Months 100 Ashraf Elmaraghy, Fatma Soliman E Ebeid 2020-10-16
COPP2-study: Clinical features of COVID-19 in pediatric patients, long-term effects Coronavirus disease 19 infection Amsterdam UMC Netherlands 2020-10-01 2022-03-01 COPP2-study, NL8926 Phase Not Applicable Not yet recruiting 1 17 Months 120 Caroline Kosterink-Brackel 2020-10-15
LIVECOVIDFREE: Lung Structure-Function In Survivors of Mild and Severe COVID-19 Infection Coronavirus disease 19 infection 6 min walk test alone, biological sampling alone, computed tomography alone, forced oscillation technique alone, hyperpolarized xenon-129 alone, magnetic resonance imaging alone, plethysmography alone, spirometry alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Western Ontario London Health Sciences Centre Research Inc Canada 2020-12-01 2024-12-01 LIVECOVIDFREE, NCT04584671, ROB0050 Phase Not Applicable Not yet recruiting 1 48 Months 200 Angela Wilson, RRT, Grace E Parraga, PhD 2020-10-15
ReCOVer: Cognitive Behavioral Therapy for post-COVID-19 fatigue Coronavirus disease 19 infection, Fatigue internet-based cognitive behavioral therapy (iCBT) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Amsterdam UMC The Netherlands Organisation for Health Research and Development Netherlands 2020-10-05 2022-10-05 NL8947, ReCOVer Phase Not Applicable Recruiting 1 24 Months 114 Tanja Kuut 2020-10-16
COVSPERM: Pilot Study to Detect SARS-CoV-2 Virus in Sperm Coronavirus disease 19 infection blood sampling alone, nasopharyngeal sampling alone, saliva sampling alone, semen sampling alone, urine sampling alone Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Centre Hospitalier Universitaire de Toulouse France 2020-10-31 2022-02-28 2020-A01610-39, COVSPERM, NCT04584593, RC31/20/0202 Phase Not Applicable Not yet recruiting 1 16 Months 50 Louis BUJAN, PR, Louis BUJAN, Pr 2020-10-16
Investigation of Validity and Reliability of Post-COVID-19 Functional Status Scale Coronavirus disease 19 infection Data collection alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hacettepe University Turkey 2020-09-02 2021-12-02 GO 20/788, NCT04584450 Phase Not Applicable Recruiting 1 15 Months 100 Aslihan Cakmak, Aslıhan Çakmak, Deniz Inal-Ince, Ebru Calik Kutukcu, Ebru Çalık-Kütükcü, Esra Kınacı, Gülay Sain-Güven, Lale Özışık, Melda Saglam, Naciye Vardar-Yagli, Nursel Çalık-Başaran, Oğuz Abdullah Uyaroğlu 2020-10-15
COVIRIC: Sars-Cov-2 Viral Infection (COVID-19) in Patients With Chronic Inflammatory Rheumatism Coronavirus disease 19 infection, Rheumatoid arthritis, Spondylarthritis immune response assessment alone, immunosuppressive therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-06-11 2023-12-31 APHP200598, COVIRIC, NCT04584541 Phase Not Applicable Recruiting 1 42 Months 150 Adèle bellino, Corinne Miceli-Richard, MD, PhD 2020-10-17
Study to Evaluate the Safety, Pharmacokinetics and Efficacy of STI-2020 (COVI-AMG) in Outpatients With COVID-19 Coronavirus disease 19 infection COVI-AMG alone, standard of care alone COVID19 Spike glycoprotein inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sorrento Therapeutics Inc 2020-12-31 2021-04-30 AMG-COV-101, NCT04584697 Phase 1/Phase 2 Clinical Not yet recruiting 0 4 Months 50 Mike Royal, MD 2020-10-16
Prognostic Factors and Outcomes of COVID-19 Cases in Ethiopia Coronavirus disease 19 infection Ethiopian Public Health Institute Dutch Ministry of Health, Welfare and Sport Ethiopia 2020-10-30 2021-11-14 EPHI NATIONAL COHORT, NCT04584424 Phase Not Applicable Not yet recruiting 1 12 Months 6390 Masresha Tessema, Masresha Tessema, PhD, Saro Abdella, MPhil, Saro Abdella, mPhil 2020-10-15
An observational, clinical series study to evaluate the effect of sarilumab in patients with COVID‐19 pneumonia Coronavirus disease 19 infection, Viral pneumonia Variable regimens including azithromycin , cobicistat , darunavir , enoxaparin sodium , hydroxychloroquine , sarilumab Cytochrome P450 3 inhibitor, IL-6 receptor antagonist, Low molecular weight heparin San Giovanni di Dio Hospital Phase Not Applicable Status not specified 0 8 2020-10-14
An observational and single-center study of hydroxychloroquine treatment in COVID-19 in Wuhan, China Coronavirus disease 19 infection hydroxychloroquine alone Tongji Hospital China Phase Not Applicable Status not specified 1 30 2020-10-14
Telerehabilitation for elderly people with Alzheimer's disease and their caregivers Alzheimers disease, Coronavirus disease 19 infection Telerehabilitation alone, cognitive and multicomponent motor exercises alone, psychoeducation alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundação Universidade Federal De São Carlos Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Brazil 2020-09-20 2021-06-25 4.255.764, RBR-825p57, U1111-1252-3238, _89476318.0.0000.5504 Phase Not Applicable Recruiting 1 9 Months 48 Carla A. Andreatto, Carolina Tsen, Larissa Pires de Andrade 2020-10-19
A phase II clinical trial MVA-SARS-2-S vaccine for the potential prevention of COVID-19 infection Coronavirus disease 19 infection MVA-SARS-2-S alone COVID19 Spike glycoprotein modulator Universitätsklinikum Hamburg-Eppendorf Germany 2020-12-31 Phase 2 Clinical Planned 4 2020-10-14
Prolonged Prone Positioning for COVID-induced Acute Respiratory Distress Syndrome (ARDS): A Pilot Study Coronavirus disease 19 infection, Respiratory distress syndrome Prolonged Proned Positioning alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Alabama at Birmingham US 2021-01-31 2021-06-30 IRB-300005979, NCT04581811 Phase Not Applicable Not yet recruiting 1 5 Months 52 David B Page, M.D., David Page, Derek Russell, M.D., Mark Dransfield, M.D. 2020-10-15
coVIHd-19: Impact of the Epidemic of COVID-19 Infection Among People Living With HIV (SARS-CoV-2) Coronavirus disease 19 infection, HIV infection questionnaire alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier de Tourcoing France 2020-10-31 2021-12-31 NCT04581746, RIPH_2020_7, coVIHd-19 Phase Not Applicable Not yet recruiting 3 14 Months 1800 Emmanuelle AISSI, MD, Jean Luc SCHMIT, PU-PH, Pauline THILL, MD, Solange TREHOUX, PhD 2020-10-15
Group CBT For Perinatal Anxiety Coronavirus disease 19 infection Group Cognitive Behaviour Therapy for Perinatal Anxiety (CBT-PA) alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Manitoba Canada 2020-10-31 2021-09-30 H2020:095, NCT04581681 Phase Not Applicable Not yet recruiting 1 11 Months 50 Gillian Alcolado 2020-10-18
A phase Ib/IIa clinical study to assess VIR-7832 in the treatment of patients with SARS-CoV-2 infection Coronavirus disease 19 infection VIR-7832 alone COVID19 Spike glycoprotein modulator GlaxoSmithKline plc, Vir Biotechnology Inc 2020-12-31 Phase 1/Phase 2 Clinical Planned 0 2020-10-14
CAMELOT: Camostat Efficacy versus Placebo for Outpatient Treatment of COVID-19 Coronavirus disease 19 infection camostat mesylate alone Serine protease inhibitor, Transmembrane serine protease 2 inhibitor, Trypsin inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sagent Pharmaceuticals Inc US 2020-10-31 2021-01-31 CAMELOT, NCT04583592, NI03-CV19-001 Phase 2 Clinical Not yet recruiting 12 3 Months 300 Atasi Jana, M.D., Brett Foster, Cheryl Hargrove, Erin Kelly, Jackie Duckett, Janet Nuttall, M.P.H., Janett Jalil, Julie Lafave, Niurka Romero, Olia Nayor, Priscilla Hernandez, Rabia Gilani, Yelamis Cartaya, Yeslin Arias 2020-10-28
Mental Imagery to Increase Face Covering Use in UK-based Public Places During the COVID-19 Pandemic Coronavirus disease 19 infection Mental imagery alone, Process imagery alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of East London University of Manchester UK 2020-08-19 2020-12-01 ETH2021-0006, NCT04583449 Phase Not Applicable Recruiting 1 3 Months 250 Dominic Conroy, PhD 2020-10-15
ImmuneSense COVID-19 Study Coronavirus disease 19 infection T-Detect SARS-CoV-2 assay alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Adaptive Biotechnologies Corp Covance Inc US 2020-10-09 2021-01-09 NCT04583982, PRO-00781 Phase Not Applicable Not yet recruiting 1 3 Months 125 Jennifer Dines, MD, Jia Qadeer, Sarah Duffy, Thomas Manley, MD 2020-10-14
Validation of a Rapid, Non-invasive Point-of-care IVD Test for Diagnosis of SARS-COV-2 (COVID-19) Infection (EasyCov) Coronavirus disease 19 infection EasyCov IVD test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Firalis SAS Istanbul University Turkey 2020-10-31 2021-03-31 NCT04583319, ST0194 Phase Not Applicable Recruiting 1 5 Months 160 Arif Atahan, Prof.MD, Rodwell Mkhwananzi, MD, Selçuk Şen, Stéphanie Boutillier, PhD 2020-10-22
TeleCCCAP: Feasibility and Quality of TeleConsultation in Pediatric Anesthesia Anesthesia, Coronavirus disease 19 infection teleconsultation alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Centre Hospitalier Universitaire de Toulouse France 2020-10-07 2022-03-14 2020-A02275-34, NCT04583865, RC31/20/0220, TeleCCCAP Phase Not Applicable No longer recruiting 1 17 Months 400 KERN Delphine, MD 2020-10-13
Negative predictive value of the FebriDx host response point-of-care test in patients presenting to a single Australian Emergency Department with suspected COVID-19 Coronavirus disease 19 infection FebriDx finger prick test alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Planet Innovation Australia 2020-11-01 2022-05-31 ACTRN12620001029987p, ANZCTR379997 Phase Not Applicable Not yet recruiting 1 19 Months 300 Paul Buntine, Shelley Westgarth-Nugent 2020-10-15
BET-B; ACTIV-5/BET study: ACTIV-5/Big Effect Trial (BET-B) for the Treatment of COVID-19 Coronavirus disease 19 infection lenzilumab plus remdesivir COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, GM-CSF ligand inhibitor, Immunoglobulin G1 modulator, Immunoglobulin kappa modulator, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Humanigen Inc, National Institute of Allergy and Infectious Diseases National Institutes of Health US 2020-10-19 2021-07-01 20-0013B, BET-B, ACTIV-5/BET study, NCT04583969 Phase 2 Clinical Recruiting 5 8 Months 200 20-0013 Central Contact 2020-10-27
Evaluation of the Performance of the Covid-19 Ag BSS Rapid Antigenic Test in Symptomatic Children in a Pediatric Emergency Department Coronavirus disease 19 infection Biosynex Covid-19 Ag-BSS test alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Centre Hospitalier Intercommunal Creteil France 2020-10-01 2021-01-01 NCT04583189, SPEEDYCOVI Phase Not Applicable Recruiting 1 3 Months 500 BISCARDI Sandra, MD, Camille JUNG, Ph D 2020-10-21
A clinical study to assess the efficacy and safety of Tinefcon in patients with moderate COVID-19 infection Coronavirus disease 19 infection Tinefcon alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Life Molecular Imaging India 2020-10-12 CTRI/2020/10/028335, Tinefcon/01/20 Phase 3 Clinical Not yet recruiting 4 60 Dr Alben Sigamani, Dr Mala Kaneria, Dr Mehul Shah, Dr Rahul Tambe, Mridul Sharma, Rajiv Salvi 2020-10-15
Prospective on evaluation of use of , “AyurCoro3” as an add on medication for the treatment purpose in COVID-19 patients Coronavirus disease 19 infection AyurCov3 alone, Standard of Care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shri Sarveshwar Seva Samstha India 2020-10-13 CTRI/2020/10/028333 Phase 3 Clinical Not yet recruiting 1 500 Dr Nanasaheb Memane, Dr Vijaykumar Gawali 2020-10-28
ACTIV-5/BET-A study: Big Effect Trial (BET-A) for the Treatment of COVID-19 Coronavirus disease 19 infection remdesivir plus risankizumab COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, IL-23 antagonist, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Allergy and Infectious Diseases National Institutes of Health US 2020-10-14 2021-07-01 20-0013A, ACTIV-5/BET-A study, NCT04583956 Phase 2 Clinical Recruiting 8 8 Months 200 20-0013 Central Contact 2020-10-27
DYSPO: Photoplethysmographic Scaling of Dyspnea Coronavirus disease 19 infection, Dyspnea, Respiratory failure ECG alone, Pulse oximeter alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Institutul de Urgenta pentru Boli Cardiovasculare Prof.Dr. C.C. Iliescu Romania 2020-10-01 2021-07-30 18751, DYSPNOEA - SPO2 CURVE STUDY, DYSPO, NCT04582838 Phase Not Applicable Recruiting 2 9 Months 60 Balan Cosmin, Consultant, Balan Ion Cosmin, Cristian Cobilinschi, Consultant, Serban I Bubenek Turconi, Professor 2020-10-14
Differential Expression of Cytokines, Transcriptome and miRNA in Coronavirus Disease 2019 (COVID-19) Egyptian's Patients Coronavirus disease 19 infection C-reactive protein test alone, D-dimer test alone, PCR test alone, complete blood count test alone, cytokine profiling alone, differential leukocyte test alone, ferritin test alone, miRNA analysis alone, transcriptome analysis alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tanta University Egypt 2020-10-04 2022-10-03 CTM_COVID-19, NCT04583566 Phase Not Applicable Recruiting 2 24 Months 40 Mohammed Eid, Doctor, Mohammed El Shanshoury, Professor, Mohammed Hanteera, Professor 2020-10-14
KNC19: Knust COVID-19 Clinical Trial Coronavirus disease 19 infection Nibima alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) kwame Nkrumah University of Science and Technology Ghana 2020-12-01 2021-01-29 KNC19, PACTR202010690466874 Phase 2 Clinical Not yet recruiting 1 1 Month 20 Ellis Owusu Dabo, Mohamed Mutocheluh 2020-10-14
Send-In Sample Collection for Comprehensive Analyses of Innate and Adaptive Immune Responses During Acute COVID-19 and Convalescence Coronavirus disease 19 infection Healthy volunteers accepted, Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Allergy and Infectious Diseases National Institutes of Health Clinical Center US 2020-11-02 2025-08-31 000044-I, 10000044, NCT04582903 Phase Not Applicable Recruiting 1 57 Months 500 Helen C Su, M.D., Helen Su, M.D. Ph. D, Sandra M Maxwell, R.N. 2020-10-29
Comparison of the effectiveness of two treatment regimens in patients with COVID-19 Coronavirus disease 19 infection Sovodak (Faravan Rojan Mohaghegh Darou) plus hydroxychloroquine (Iran Daru) Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Iran University of Medical Sciences Iran 2020-07-19 IR.IUMS.FMD.REC.1399.407, IRCT20200328046885N1 Phase 2 Clinical No longer recruiting 2 300 Dr Abbas Motevalian, Mahin Jamshidi Makiani 2020-10-15
NICORISCOVID: Tobacco and Nicotine Consumption and the Risk of Acquisition of Coronavirus Disease 2019 (COVID-19) Coronavirus disease 19 infection RT-PCR alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-10-12 2020-12-01 APHP200663, NCT04583761, NICORISCOVID Phase Not Applicable Not yet recruiting 1 1 Month 1000 Marina Karmochkine, MD 2020-10-15
Evaluate the Safety, Tolerability, Pharmacodynamics, Pharmacokinetics, and Immunogenicity of HLX-71 (Recombinant Human Angiotensin-converting Enzyme 2-Fc Fusion Protein for COVID-19) in Healthy Adult Subjects Coronavirus disease 19 infection HLX-71 alone Angiotensin converting enzyme 2 inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hengenix Biotech Inc US 2020-11-30 2021-05-31 HLX71-001US-253460, NCT04583228 Phase 1 Clinical Not yet recruiting 1 6 Months 40 Esther Yoon, MD, Jinyun Bai 2020-10-15
Physical Activity Levels of Hypertensive and Healthy Individuals Under Social Isolation During the COVID-19 Pandemic Coronavirus disease 19 infection, Hypertension Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hacettepe University Turkey 2020-06-01 2021-02-01 GO 20/610, NCT04583345 Phase Not Applicable Recruiting 1 8 Months 32 Beyza Nur Karaduz, MSc, Ebru Calik Kutukcu, PhD, Naciye Vardar Yagli, PhD, S. Lale Tokgozoglu, Professor, Yusuf Ziya Sener, MD 2020-10-20
NICOVID-PREV: Efficacy of Nicotine in Preventing COVID-19 Infection in Caregivers Coronavirus disease 19 infection Nicotine patch (Nicopatchlib) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-10-31 2021-10-31 2020-003722-23, APHP200538, NCT04583410, NICOVID-PREV Phase 3 Clinical Not yet recruiting 2 12 Months 1633 Florence TUBACH, MD, Guylaine LABRO, MD, Raphael GAILLARD, MD, Zahir AMOURA, MD 2020-10-20
AIDED: Acute Kidney Injury in Covid-19 Coronavirus disease 19 infection, Renal injury Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospitals Of Derby and Burton NHS Foundation Trust UK 2020-11-30 2022-09-30 AIDED, NCT04583293, UHDB/2020/076 Phase Not Applicable Not yet recruiting 1 22 Months 220 Maarten W Taal, Professor, Nitin V Kolhe, Doctor 2020-10-24
DISCOVER: The Salivary Raman COVID-19 Fingerprint Coronavirus disease 19 infection Aramis Raman microscope (Horiba Jobin-Yvon) alone, Raman spectroscopy alone, portable Raman spectrometer alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fondazione Don Carlo Gnocchi - Onlus Italy 2020-06-01 2021-06-01 DISCOVER, FDG_SALIVACOVID01, NCT04583306 Phase Not Applicable Recruiting 2 12 Months 120 Cristiano Carlomagno, PhD, Jorge Navarro, MD, Luca C Bianchi, MD, Marzia Bedoni, PhD, Paolo I Banfi, MD 2020-10-14
Evaluation of the efficacy and safety of Atazanavir/Ritonavir plus Hydroxychloroquine regimen in patients with moderate COVID-19 Coronavirus disease 19 infection, Viral pneumonia atazanavir sulfate + ritonavir (HIV infection), Mylan Laboratories plus hydroxychloroquine HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Mazandaran University of Medical Sciences Iran 2020-08-22 IR.MAZUMS.REC.1399.602, IRCT20200328046886N2 Phase 3 Clinical Recruiting 1 120 Hamideh Abbaspour Kasgari, Hamideh Abbaspour kasgari, Research and technology department 2020-10-14
A study to analyze results of COVID-19 testing in anesthesia procedures using the polymerase chain reaction (PCR) Coronavirus disease 19 infection polymerase chain reaction (PCR) test alone American Society of Anesthesiologists US Phase Not Applicable Status not specified 1 1033 2020-10-18
A clinical study of Reveal 35C in the detection of pneumonia (including COVID-19) Coronavirus disease 19 infection, Viral pneumonia Reveal 35C alone KA Imaging Inc Canada Phase Not Applicable Status not specified 1 2020-10-13
Association of calcium channel blocker use with COVID-19 clinical outcome: a metaanalysis Cardiovascular disease, Coronavirus disease 19 infection calcium channel blocker therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitas Airlangga Asia 2020-10-11 UMIN000042076 Phase Not Applicable Recruiting 0 1000 Eka Mulia, Mochamad Yusuf 2020-10-14
Effectiveness of favipiravir in comparison with tenofovir alafenamid in patients with COVID-19 Coronavirus disease 19 infection favipiravir (Nafas farmed Co) alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ardabil University of Medical Sciences Iran 2020-09-20 IR.ARUMS.REC.1399.310, IRCT20150808023559N23 Phase 2 Clinical Recruiting 1 100 Dr Farhad Pourfarzi, Somaieh Matin 2020-10-14
A Global, Phase IIb/III Clinical Trial to Assess the Effect of CV-07050101 in Patients With Coronavirus Disease 19 Infection Coronavirus disease 19 infection SARS-CoV-2 mRNA vaccine (COVID-19), CureVac alone COVID19 Spike glycoprotein modulator CureVac AG 2020-12-31 Phase 2/Phase 3 Clinical Planned 0 30000 2020-10-13
COVID-19 Watch + COVID-19 Pulse Coronavirus disease 19 infection COVID Watch alone, PCORI Pulse alone, automated text-messaging program alone, telemedicine nurse-led care alone, triage protocol alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Pennsylvania 2020-10-21 2021-10-31 844043, NCT04581863 Phase Not Applicable Not yet recruiting 0 12 Months 850 Dina Abdel-Rahman, BS, Jessie Hemmons, MS 2020-10-14
Effect of Beta-interferon and methylprednisolone in COVID-19 Coronavirus disease 19 infection Variable regimens including Keltra , beta-interferon , hydroxychloroquine , methylprednisolone , naproxen Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shahid Sadoughi University of Medical Sciences and Health Services Iran 2020-05-04 IR.SSU.REC.1399.040, IRCT20200825048514N1 Phase 3 Clinical No longer recruiting 1 60 Fatemeh sadat Aghaei meybodi, Masoud Mirzaei 2020-10-14
A Phase I/II Study to Assess the Safety, Tolerability and Pharmacokinetics of NGM-621 in Healthy Subjects, and to Assess the Safety, PK and Efficacy in Subjects With Moderate to Severe ARDS Caused by COVID-19 Adult respiratory distress syndrome, Coronavirus disease 19 infection NGM-621 alone Complement C3 inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) NGM Biopharmaceuticals Inc 2020-10-31 2021-09-30 621-CP-102, NCT04582318 Phase 1/Phase 2 Clinical Not yet recruiting 0 11 Months 48 NGM Study Director 2020-10-14
Effect of Blood Transfusion in COVID-19 Coronavirus disease 19 infection packed cell alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Boushehr University of Medical Sciences Iran 2020-10-11 IR.BPUMS.REC.1399.108, IRCT20201003048904N1 Phase 2 Clinical Recruiting 1 40 Farhad Abbasi, Farhad abbasi, Gholamreza khamisipour, Negar Changizi 2020-10-13
Proportional Open Ventilation (POV) Device and Its Efficacy in Managing Acute Respiratory Failure in COVID-19 Patients Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure Life2000 Ventilator alone, high-flow nasal cannula therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hill-Rom Holdings Inc US 2020-08-28 2020-10-31 CR-RR-2020-004, NCT04581161 Phase Not Applicable Recruiting 1 2 Months 10 Jonathan Shelver, MD, Malia Remackel, Marissa Peterson 2020-10-13
Comparison of tocilizumab versus itolizumab in covid-19 patient Coronavirus disease 19 infection tocilizumab alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) All India Institute of Medical Sciences Patna India 2020-10-19 CTRI/2020/10/028325 Phase 2 Clinical Not yet recruiting 1 50 Dr Poonam kumari 2020-10-20
Study to Investigate Long-term Pulmonary and Extrapulmonary Effects of COVID-19 Coronavirus disease 19 infection, Lung disease Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Inselspital, Berne Switzerland 2020-05-01 2023-06-01 2020-00799, NCT04581135 Phase Not Applicable Recruiting 9 37 Months 500 Christian Clarenbach, PD, Christian Garzoni, PD, Christophe von Garnier, Prof., Kurt De Jaegere, Manuela Funke-Chambour, MD, Manuela Funke-Chambour, PD, Marco Mancinetti, MD, Martin Brutsche, Prof., Paola Gasche Soccal, Prof., Pierre-Olivier Bridevaux, Prof., Sebastian R. Ott, PD 2020-10-13
COVID-IYON: Study Examining Data Pertaining to Clinical Outcomes and Organizational Responses to the 2020 SARS-CoV-2 Pandemic Cancer, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cancer Trials Ireland Ireland 2020-04-29 2021-06-30 COVID-IYON, CTRIAL-IE 20-01, NCT04581070 Phase Not Applicable Recruiting 11 14 Months 300 Dr. Andrew Hodgson, Dr. Anne Fortune, Dr. Derville O'Shea, Dr. Ezzat ElHassadi, Dr. Gerard Crotty, Dr. Janusz Krawczyk, Dr. Larry Bacon, Dr. Liam Smyth, Dr. Paula Calvert, Dr. Ruth Clifford, Dr. Ruth Morrell, Dr. Silvie Blazkova, Dr. Sinéad Cuffe, Dr. Siobhan Glavey, Prof. Bryan Hennessy, Prof. Cathy Kelly, Prof. Helen Enright, Prof. Janice Walshe, Prof. Linda Coate, Prof. Roisin Connolly 2020-10-14
An Experiment to Evaluate the Safety of agenT-797 in COVID-19 Patients With Severe Difficulty Breathing Coronavirus disease 19 infection, Respiratory distress syndrome agenT-797 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) AgenTus Therapeutics Inc Agenus Inc US 2020-09-21 2021-10-15 C-1300-01, NCT04582201 Phase 1 Clinical Recruiting 1 12 Months 55 Agenus, Inc. Clinical Trial Information, Koen Van Besien, MD, Koen Van Besien, MD, PhD, Medical Director 2020-10-13
Assessment of memory cells response to Mycobacterium Indicus Pranii vaccination Coronavirus disease 19 infection, Mycobacterium infection Mycobacterium Indicus Pranii (MIP) Vaccine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Manashi Chakrabarti Foundation India 2020-10-20 CTRI/2020/10/028326, NKPROTOCOL0401 Phase 2 Clinical Not yet recruiting 1 40 Dr Jyoti Rastogi, Dr Suparno Chakrabarti 2020-10-20
SARS-CoV2_KIDS: SARS-CoV2 Antibodies in Pediatric Patients (COVID-19) Coronavirus disease 19 infection Healthy volunteers accepted, Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) University of Erlangen-Nurnberg Medical School Germany 2020-10-05 2022-05-31 405_20 BC, NCT04581148, SARS-CoV2_KIDS Phase Not Applicable Not yet recruiting 1 19 Months 2000 Adrian Regensburger, MD, Antje Neubert, PhD 2020-10-13
AyurCoro3 Prophylaxis: Evaluation of use of , 'study medication' for prophylaxis in frontline health care workers involved in treating COVID-19 patients Coronavirus disease 19 infection AyurCoro-3 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bhaktivedanta Hospital and Research Institute India 2020-10-09 AyurCoro3 Prophylaxis, CTRI/2020/10/028324 Phase 2 Clinical Not yet recruiting 1 120 Dr Nanasaheb Memane, Dr Vijaykumar Gawali 2020-10-15
An Online-platform to Improve Patient-centered Care During the COVID-19 Pandemic: a GIMEMA Surveillance Program in Hematological Malignancies Coronavirus disease 19 infection, Hematological neoplasm IMEMA-ALLIANCE Platform online monitoring system alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gruppo Italiano Malattie EMatologiche dell'Adulto 2020-10-31 2024-10-31 GIMEMA-ALLIANCE PLATFORM, NCT04581187 Phase Not Applicable Not yet recruiting 0 48 Months 400 2020-10-13
Impact of the COVID-19 pandemic on graduating dental interns: A student’s perspective Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs) Manipal College of Dental Sciences India 2020-10-21 CTRI/2020/10/028296 Phase Not Applicable Not yet recruiting 1 400 Dr Mathangi Kumar 2020-10-13
COSMIC-19: Continuous Signs Monitoring In Covid-19 Patients Coronavirus disease 19 infection Isansys Patient Status Engine alone, continuous vital sign monitoring alone, machine learning artificial intelligence technology alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The Christie NHS Foundation Trust Aptus Clinical Ltd, Manchester University NHS Foundation Trust, Zenzium Ltd UK 2020-07-11 2021-02-01 CFTSP187, COSMIC-19, NCT04581031 Phase Not Applicable Recruiting 2 6 Months 60 Anthony Wilson, Fiona Thistlethwaite, Fiona Thistlethwaite, MB BChir PhD 2020-10-14
Analysis of the SARS-CoV-2 specific immune response in persons with SARS-CoV-2 infection (COVID-19) Coronavirus disease 19 infection Healthy volunteers accepted University of Homburg Bethanien Krankenhaus gGmbH, Universitat des Saarlandes Germany 2020-10-15 76/20, DRKS00023086 Phase Not Applicable Not yet recruiting 2 190 Martina Sester, Simon Herkenrath 2020-10-13
Clinical Trial For SARS-CoV-2 Vaccine (COVID-19) Coronavirus disease 19 infection CoronaVac alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Sinovac Biotech Ltd Turkey 2020-09-14 2021-04-15 9026-ASI, NCT04582344 Phase 3 Clinical Recruiting 24 7 Months 13000 Ali Mert, Prof., Alpay Azap, Prof., Assoc. Prof., Aydın Yılmaz, Prof., Emin Halis Akalın, Prof., Fatma Şebnem Erdinç, Prof., Gülgün Dilek Arman, Prof., Gürdal Yılmaz, Prof., Hatice Rahmet Güner, Prof., Hüsnü Pullukçu, Prof., Murat Akova, Prof., Murat Akova, Professor, Mustafa Kemal Çelen, Prof., Sedat Altın, Prof., Serap Şimşek Yavuz, Prof., Serhat Ünal, Prof., Sıla Akhan, Prof., Taner Yıldırmak, Assoc. Prof., Taner Yıldırmak, Prof., Volkan Korten, Prof., Yaşar Bayındır, Prof., Yeşim Taşova, Prof., Ömer Fehmi Tabak, Prof., Özgür Batum, Specialist, İftihar Köksal, Prof., İlhami Çelik, Prof., İlkay Karaoğlan, Prof., Şükran Köse, Prof. 2020-10-13
Validation of Laboratory Techniques, Strategies, and Types of Samples for Epidemiological Control in the Covid-19 Pandemic Coronavirus disease 19 infection LAMP technique alone, Pool LAMP alone, Pool RT-PCR alone, RT-PCR alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) CUNY Hunter College Universidad Autonoma Juan Misael Saracho Bolivia 2020-10-08 2020-11-30 NCT04581083, PROY - UAJMS001/2020 Phase Not Applicable Recruiting 1 1 Month 30 Carmen Amanda Delagadillo Delgadillo, MD, Jimena Martinez, MD, Jorge Tejerina, Lic., Kenji Shoji, PhD, Lucia Alvarado Arnez, PhD, Paloma Rojas Saunero, MD, MSc, Rodrigo Arce Cardozo, Rodrigo Arce Cardozo, MD, MPH, Rodrigo Arce Cardozo, MD,MPH, Roxana Valdez Zamorano, Wilson Muriel Argollo, MD 2020-10-21
PHRUCov01: Trial of Triazavirin (TZV) for the Treatment of Mild to moderate COVID-19 Coronavirus disease 19 infection standard of care treatment alone, triazavirin alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Wits Health Consortium (Pty) Ltd Perinatal HIV Research Unit, PharmaCentrix (Pty) Ltd, University of the Witswatersrand South Africa 2020-09-08 2021-12-31 NCT04581915, PHRU COV01, PHRUCov01 Phase 2/Phase 3 Clinical Recruiting 1 15 Months 420 Fatima Mayat, Firdaus Nabeemeeah, MBBCh, Neil A Martinson, MBChB, Tumelo Moloantoa, MBChB 2020-10-20
A phase III, global. non-contact trial to assess CoronaVac in healthcare workers in Dhaka, Bangladesh Coronavirus disease 19 infection CoronaVac alone LSK Global Pharma Services Co Ltd Bangladesh Phase 3 Clinical Planned 1 4200 2020-10-12
CLASSIC: Perceptions of the Clinical and Psychosocial Impact of Covid-19 in Patients With Neuromuscular and Neurological Disorders Coronavirus disease 19 infection, Duchenne dystrophy, Neurological disease, Neuromuscular disease, Spinal muscular atrophy Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Royal Brompton & Harefield NHS Trust UK 2020-09-11 2020-12-17 286495, CLASSIC, NCT04581577 Phase Not Applicable Recruiting 1 3 Months 75 Anita K Simonds, MD MBBS, Anita Simonds, MBBS, Kinesh Patel, PhD, Lydia A Spurr, MBBS BMedSci, Lydia Spurr, MBBS, Martin R Cowie, MD MSc, Mary Morrell, PhD 2020-10-13
Oscillation and Lung Expansion Therapy in Patients With COVID-19 Coronavirus disease 19 infection MetaNeb System alone, oscillation and lung expansion (OLE) therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hill-Rom Holdings Inc Emory University, Northwestern University US 2020-09-28 2021-01-01 CR-RR-2020-002, NCT04582214 Phase Not Applicable Recruiting 2 3 Months 30 Brian Becker, RT, Colin Swenson, MD, Elizabeth Cox, Lindsay Downing, MPH, Lisa Wolfe, MD, Phill Cooper 2020-10-13
Coro-Buddy: Buddy) Prevalence of Antibodies Against SARS-CoV-2 Virus That Causes COVID-19 in Tubingen Children Coronavirus disease 19 infection Healthy volunteers accepted, Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Tubingen Germany 2020-07-02 2021-12-31 CORO-BUDDY, Coro-Buddy, NCT04581889 Phase Not Applicable Recruiting 1 17 Months 2380 Andrea Kreidenweiss, Dr., Jana Held, Dr, Jana Held, Dr., Rolf Fendel, Dr., Yudi Tatiana Röckl-Pinilla, Dr. 2020-10-15
PK and Safety of Remdesivir for Treatment of COVID-19 in Pregnant and Non-Pregnant Women in the US Coronavirus disease 19 infection remdesivir alone COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) International Maternal Pediatric Adolescent AIDS Clinical Trials Group US, Puerto Rico 2020-10-15 2022-01-15 DAIDS STUDY ID 38746, IMPAACT 2032, NCT04582266 Phase Not Applicable Not yet recruiting 17 15 Months 40 Adriana Drada, FMD, CCRP, Aleisha Collinson-Streng, RN, BSN, Alice Stek, MD, Allison Agwu, MD, Barsha Chakraborty, BS, Brookie Best, PharmD, MAS, Christy Beneri, DO, Debra McLaud, RN, Diana Clarke, PharmD, Elizabeth Greene, MPH, Ellen Chadwick, MD, Ellen Cooper, MD, MPH, Gwendolyn Scott, MD, Irma L. Febo Rodriguez, M.D., Jaime Deville, MD, Katherine Knapp, MD, Kathleen George, MPH, LaTeshia Thomas-Seaton, Lourdes Topete, RN, Margaret Sanders, MPH, Mariam Aziz, MD, Mark Mirochnick, MD, Martina Badell, MD, Mary Paul, MD, Maureen McNichols, MSN, CCRP, Megan Loughran, Michele Carter, BS, RN, Mobeen Rathore, MD, Nina Sublette, PhD, APRN-BC, Ruth E. Santos, RN, MPH, BSN, Saniyyah Mahmoudi, ARNP, Shelley Buschur, RN, CNM, Stephen Spector, MD 2020-10-13
MEDyMAP: Mapping COVID-19 Spread in a Tertiary Hospital Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital General Universitario de Valencia University of Valencia Spain 2020-10-02 2021-06-15 COVID19-MAPA, MEDyMAP, NCT04581096 Phase Not Applicable Recruiting 1 8 Months 3000 Adina Iftimi, PhD, Carolina Romero García, PhD, Carolina S Romero Garcia, PhD, Carolina Soledad Romero Garcia 2020-10-13
A phase II clinical trial of CYP-001 for the treatment of respiratory distress associated with COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome mesenchymoangioblast-derived mesenchymal stem cell therapy (Cymerus, critical limb ischemia/graft versus host disease/asthma/diabetic foot ulcer), Cynata/FUJIFILM alone Cynata Therapeutics Ltd Phase 2 Clinical Planned 0 2020-10-12
Patients Reactions Towards Their Diagnosis as Having COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) ClinAmygate Egypt 2020-10-10 2020-11-15 NCT04581928, PR0020 Phase Not Applicable Not yet recruiting 1 1 Month 300 Emad R Issak, MD 2020-10-13
Impact of COVID-19 on Psoriasis Practice Coronavirus disease 19 infection, Psoriasis Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cairo University Egypt 2020-09-17 2020-10-31 KAPU2020 10, NCT04581044 Phase Not Applicable Recruiting 1 1 Month 150 Asmaa Abdelnaby, MD, Mohamed HM EL-Komy, MD, Mona El-Kalioby, MD 2020-10-13
A pivotal, randomized, double-blind study to evaluate CPI-006 in hospitalized COVID-19 patients Coronavirus disease 19 infection CPI-006 alone CD73 antagonist Corvus Pharmaceuticals Inc Phase Not Applicable Planned 0 2020-10-12
A randomized, phase II clinical trial to assess safety and efficacy of KT-PC-301 in the treatment of subjects with COVID-19-related acute respiratory disease syndrome (ARDS) Coronavirus disease 19 infection, Respiratory disease KT-PC-301 alone Koligo Therapeutics Inc US Phase 2 Clinical Planned 1 75 Mohamed Saad, MD 2020-10-26
Evaluation of the effectiveness of intravenous infusion of human COVID-19 hyperimmune plasma with specific antibody titer in hospitalized patients with Covid-19: a randomized clinical trial Coronavirus disease 19 infection, Viral pneumonia human COVID-19 hyperimmune plasma alone, human COVID-19 hyperimmune plasma with antibody titer alone, routine treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tehran University of Medical Sciences Iran 2020-10-11 IR.TUMS.MEDICINE.REC.1399.436, IRCT20201004048922N1 Phase 3 Clinical Recruiting 1 75 Hamidreza Abtahi, Mohammadali Sahraeiyan, Mohammadreza Salehi, Parisa Kianpour 2020-10-13
Study of resistance to COVID-19 of medical staff (Pilot Study) Acute stress disorder, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Japanese Ministry of Health, Labor and Welfare Japan 2020-09-25 UMIN000042061 Phase Not Applicable Not yet recruiting 1 165 Hirayasu Kai, Kunihiro Yamagata 2020-10-29
Perception Of Dentists On Infection Control Measures During Novel Corona Virus (COVID-19) Pandemic Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Manipal College of Dental Sciences India 2020-10-25 CTRI/2020/10/028295 Phase Not Applicable Not yet recruiting 1 400 Dr Neetha Shenoy 2020-10-13
CoTroxCov Study: Cotrimoxazole in hospitalised patients with moderate to early-severe COVID-19 infection Coronavirus disease 19 infection cotrimoxazole alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ministry of Health and Family Welfare India 2020-10-26 CTRI/2020/10/028297, CoTroxCov Study, U1111-1259-2654 Phase 2 Clinical Not yet recruiting 1 200 Dr Santanu Kumar Tripathi 2020-10-14
COVID-19, Prediction Model, Prognosis Coronavirus disease 19 infection prediction model alone Hospital Sungai Buloh Malaysia 2020-10-15 2022-09-15 56523, NMRR-20-2149-56523 Phase Not Applicable Status not specified 1 23 Months 1500 DR THARMINI A/P RAVI, Dr Sharifah Khairul Atikah 2020-10-13
COVIDstroke: Effect of COVID-19 pandemic on stroke admission trend in Malaysia Coronavirus disease 19 infection, Stroke Sultanah Nur Zahirah Hospital Malaysia 2020-11-01 2021-03-31 1, 56595, COVIDstroke, NMRR-20-2148-56595 Phase Not Applicable Not yet recruiting 1 5 Months Mrs NORSIMA NAZIFAH SIDEK 2020-10-13
PoCoPoHo: Post COVID-19 Infection: Impact of Clinical Severity and Timeline on Functional Status, Symptomology and Serological Status Post-Hospitalization Coronavirus disease 19 infection Hospital Raja Permaisuri Bainun Malaysia 2020-10-01 2020-10-31 NMRR-20-2125-56457, PoCoPoHo Phase Not Applicable Status not specified 1 1 Month MOH CHENG KEAT 2020-10-13
Antibiotic-COVID-19 Coronavirus disease 19 infection antibiotics alone Hospital Raja Permaisuri Bainun Malaysia 2020-10-12 2020-11-17 56531, NMRR-20-2124-56531 Phase Not Applicable Status not specified 1 1 Month Dr Izzati Nadhirah Bt Mohamad 2020-10-20
Intranasal administration of recombinant human interferon alfa-2b as prophylaxis of SARS-CoV-2 infection. (COVID-19) Coronavirus disease 19 infection nasalferon alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Center for Genetic Engineering and Biotechnology Cuba 2020-10-12 2020-11-06 IG / IAGN / VS / 2001, RPCEC00000337 Phase 1/Phase 2 Clinical Not yet recruiting 1 80 Francisco Hernandez Bernal, Leader Josué Diaz 2020-10-13
A prospective study of CoVerity in the diagnosis of severe respiratory failure risk in patients with PCR-confirmed SARS-CoV-2 pneumonia Coronavirus disease 19 infection CoVerity COVID-19 Severity Test alone Inflammatix Inc Greece Phase Not Applicable Status not specified 1 97 2020-10-12
Understanding Immunity to the Flu Vaccine in COVID-19 Patients Coronavirus disease 19 infection flu vaccine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Stanford University National Institute of Allergy and Infectious Diseases US 2020-12-01 2022-12-01 5U19AI057229-17, IRB-58356, NCT04579588 Phase Not Applicable Not yet recruiting 1 24 Months 80 Hena Din, Kari Nadeau, MD, PhD 2020-10-12
Fostamatinib for Hospitalized Adults With COVID-19 Coronavirus disease 19 infection fostamatinib disodium alone, standard of care alone Syk tyrosine kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Heart Lung and Blood Institute Inova Health Care Services, National Institutes of Health Clinical Center US 2020-10-08 2020-12-15 000110-H, 10000110, NCT04579393 Phase 2 Clinical Recruiting 3 2 Months 60 Edwinia Battle, Jeffrey R Strich, M.D., Jennifer J Kyte, D.N.P. 2020-10-23
EPID CLUSTER: Study of COVID-19 Clusters in Pahang Coronavirus disease 19 infection Jabatan Kesihatan Negeri Pahang Malaysia 2020-10-06 2020-10-21 55739, EPID CLUSTER, NMRR-20-2162-55739 Phase Not Applicable Status not specified 1 Dr WAN ABDUL RAHIM B WAN MUHAMMAD 2020-10-12
SeCuRE Study: Social isolation, depression, anxiety and resilience among older adults in Klang Valley during the COVID-19 crisis Anxiety disorder, Coronavirus disease 19 infection, Depression Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Selayang Hospital Malaysia 2020-11-02 2022-01-03 55538, NMRR-20-2169-55538, SeCuRE Study Phase Not Applicable Not yet recruiting 2 14 Months Dr Zanariah Mat Saher, Dr. Nor Jannah Nasution Raduan 2020-10-12
CORONAVIT: Trial of Vitamin D to Reduce Risk and Severity of COVID-19 and Other Acute Respiratory Infections Coronavirus disease 19 infection, Respiratory tract infection vitamin D alone Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Queen Mary University of London Barts Charity, Pharma Nord ApS UK 2020-10-19 2021-06-30 289515, CORONAVIT, NCT04579640 Phase 3 Clinical Not yet recruiting 1 8 Months 5440 Adrian R Martineau, MD PhD, David A Jolliffe, PhD 2020-10-12
Assessment of COVID-19 in Tearfilm Coronavirus disease 19 infection biological sampling alone, biopsy alone, fluorescein angiography alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Vanderbilt University Medical Center US US 2020-10-09 2021-05-09 201127, NCT04579458 Phase Not Applicable Recruiting 1 7 Months 500 Sapna Gangaputra 2020-10-13
Repeat Testing for SARS-CoV-2 Coronavirus disease 19 infection RT-LAMP Assay alone, Saliva assay test alone Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Wisconsin-Madison National Institutes of Health US 2020-09-29 2021-09-30 2020-1142, 5P51OD011106-59, A536300, NCT04579549, PROTOCOL VERSION 8/17/2020, SMPH/PATHOL-LAB MED/ANAT PATH Phase Not Applicable Recruiting 1 12 Months 10000 David O'Connor, PhD 2020-10-14
Study on use of Homoeopathy Medicines in Treatment of Covid 19 cases Coronavirus disease 19 infection Homoeopathy medicine alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Ministry of Ayush India 2020-10-10 CTRI/2020/10/028233 Phase Not Applicable Not yet recruiting 1 60 Dr SUGATHAN N V 2020-10-14
REMPAR-EHPAD: Managerial and Environmental Risk for COVID 19 in French Long-Term Care Institutions Coronavirus disease 19 infection Rennes University Hospital France 2020-06-15 2020-09-01 35RC20_8898_REMPAR-EHPAD, NCT04579289, REMPAR-EHPAD Phase Not Applicable Completed 1 2 Months 230 Aline MD CORVOL 2020-10-14
COVITRA: Prevalence and Outcome of SARS-CoV-2 Infection and COVID-19 in Transplant Recipients Coronavirus disease 19 infection, Hematopoietic stem cell transplantation, Organ transplantation SARS-CoV-2 IgG test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitaire Ziekenhuizen Leuven Jessa Hospital, Katholieke Universiteit Leuven, Universiteit Hasselt, Ziekenhuis Oost-Limburg Belgium 2020-07-01 2021-12-31 COVITRA, NCT04579471, S64036 Phase Not Applicable Recruiting 1 18 Months 2000 Jef Verbeek, MD, Jef Verbeek, MD, PhD, Natalie Van den Ende, Natalie Vandenende 2020-10-12
Psychological effect of coronavirus disease 2019 on pregnant women Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs) All India Institute of Medical Sciences India 2020-10-14 CTRI/2020/10/028232 Phase Not Applicable Not yet recruiting 1 25 Dr Poonam Kumari 2020-10-12
Proof of Concept Study of Ketoji (Liquid) for its Effectiveness in Treatment and Management of COVID-19 Patients Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory tract infection Ketoji alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ruby Hall Clinic India 2020-10-12 BPLS/KTJ/2020, CTRI/2020/10/028231 Phase 2 Clinical Not yet recruiting 1 15 Dr Kapil G Zirpe, Ms Pranjal Ausekar 2020-10-15
Clinical trial of Pippali Rasayana and Nagaradi Kashaya Ghana Vati combination as an adjuvant treatment with ICMR guided medicines in Covid-19 positive mildly symptomatic cases Coronavirus disease 19 infection  ICMR directed therapy alone, Variable regimens including Nagaradi Kashaya Ghana Vati , Pippali Rasayana , Rasayana Kala , Vyanodana Kala Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) PAED'S Ayurved Rugnalaya and Sterling Multispeciality Hospital India CTRI/2020/10/028230 Phase 2 Clinical Not yet recruiting 1 60 Dr Medha Mahesh Joshi, DrYogita Abhijit Jamdade 2020-10-12
A first-in-human clinical trial of ivermectin (oral, COVID-19), MedinCell for COVID-19 Coronavirus disease 19 infection ivermectin (extended release/sc/BEPO, COVID-19), MedinCell alone MedinCell SA 2020-09-29 Phase Not Applicable Recruiting 0 2020-10-20
Corticosteroids in COVID-19 Coronavirus disease 19 infection, Viral pneumonia dexamethasone alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tehran University of Medical Sciences Iran 2020-09-26 IR.TUMS.MEDICINE.REC.1399.430, IRCT20100228003449N31 Phase 2/Phase 3 Clinical Recruiting 1 119 Hossein Khalili, Mohammad Ali Sahraian 2020-10-12
FACIAL HAIR: Facial Hair, PPE and COVID-19 Coronavirus disease 19 infection Healthy volunteers accepted Royal Cornwall Hospitals Trust UK 2020-05-14 2020-06-08 283609, FACIAL HAIR, NCT04579627 Phase Not Applicable Completed 1 358 2020-10-12
RECEDE: Regional COVID Epidemiology in England Coronavirus disease 19 infection, Renal injury Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospitals Of Derby and Burton NHS Foundation Trust UK 2020-11-01 2021-10-31 NCT04579562, RECEDE, UHDB/2020/075 Phase Not Applicable Not yet recruiting 1 12 Months 5000 Nitin V Kolhe, DM 2020-10-13
A study to know whether investigators can supervise cancer patients infected with COVID-19 from without admission in hospitals. Investigators will test how much helpful is a software called Datos health along with pulse oximeter and thermometer in this supervision by doctors Coronavirus disease 19 infection Datos Platform alone, pulse oximeter alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tata Memorial Hospital India 2020-10-13 CTRI/2020/10/028256 Phase Not Applicable Not yet recruiting 1 30 Dr Manju Sengar 2020-10-12
Psychological Impacts Of The COVID-19 Pandemic On Medical Students In India: A Web-Based Cross-Sectional Study Coronavirus disease 19 infection Young Adults (18-44 yrs) Sri Ramachandra Institute of Higher Education and Research India 2020-10-10 CTRI/2020/10/028257 Phase Not Applicable Not yet recruiting 1 500 Dr S Natarajan, Ria Tyagi 2020-10-12
Feasibility study of a mobile device for the prevention of sepsis in patients with solid tumors after chemotherapy and patients with infectiose diseases (COVID-19) Coronavirus disease 19 infection, Respiratory tract infection, Sepsis VitalPatch alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitätsklinikum Frankfurt Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie HMS Analytical Software GmbH Germany 2019-08-02 DRKS00017593, FF136/2018 Phase Not Applicable Recruiting 1 50 Mate Knabe 2020-10-20
CAMMS: Inhibiting transmission of respiratory viruses Coronavirus disease 19 infection nutraceuticals alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) India 2020-11-01 CAMMS, CTRI/2020/10/028255 Phase 2 Clinical Not yet recruiting 2 200 Dr Suman Kapur, Dr Vibhor Tak 2020-10-12
PregCOVID: Retrospective Study of Pregnancy with COVID-19 Coronavirus disease 19 infection Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Dr TMA Pai Hospital India 2020-10-08 CTRI/2020/10/028254, PregCOVID Phase Not Applicable Not yet recruiting 1 44 Shashikala Bhat 2020-10-12
Correlation Between Thoracic Ultrasound and Thorax Computed Tomography Scores Coronavirus disease 19 infection, Viral pneumonia lung ultrasound (LUS) alone, thorax computed tomography (CT) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gaziosmanpasa Taksim Research and Education Hospital Turkey 2020-06-05 2020-09-05 AYŞEV, NCT04577235 Phase Not Applicable Completed 1 3 Months 29 Ayşe Vahapoglu, M.D 2020-10-12
Effect of CBT Intervention to Improve Sleep on Wellbeing, Dietary Intake and Food Preference Coronavirus disease 19 infection, Insomnia cognitive behavioral therapy alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Glasgow UK 2020-10-05 2021-06-01 200190177, NCT04576260 Phase Not Applicable Not yet recruiting 2 7 Months 40 Ayan Merchant, MSc, Ayan Merchant, MSc., Cindy Gray, PhD, Jason Gill, PhD, Stuart Gray, PhD 2020-10-13
An observational, single-center, cohort study to evaluate the association between treatment with colchicine and improved survival of adult hospitalized patients with COVID-19 pneumonia and acute respiratory distress syndrome Coronavirus disease 19 infection, Respiratory distress syndrome colchicine alone, dexamethasone alone, hydroxychloroquine alone, lopinavir + ritonavir alone, standard of care alone, Variable regimens including dexamethasone , hydroxychloroquine , lopinavir + ritonavir HIV protease inhibitor Italy Phase Not Applicable Status not specified 1 262 2020-10-12
Q-TIP: Comparison between certified swab systems (Copan eSwab) and commercially available cotton swabs ('Q-Tip') for the detection of multi-resistant pathogens (MRE) using rectal swabs Coronavirus disease 19 infection, Infectious disease Ebelin Q-Tip cotton swab alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) UniversitätsKlinikum Leipzig Germany 2020-09-20 327/20-ek, DRKS00023249, Q-TIP Phase Not Applicable Recruiting 1 600 Johannes Wiegand 2020-10-13
Corona CPR: Impact of personal protective equipment (PPE) during a simulated cardiac arrest in times of the COVID-19 pandemic Cardiac arrest, Coronavirus disease 19 infection FFP2 personal protective equipment use alone, simulated resuscitation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Arbeitsgemeinschaft Intensivmedizin e.V Germany 2020-09-20 2020-602-f-S, Corona CPR, DRKS00023184 Phase Not Applicable Recruiting 1 400 Stephan Marsch, Timur Sellmann 2020-10-12
Effect of spiritual care based on Ghalbe Salim on anxiety related to COVID-19 (corona phobia) Anxiety disorder, Coronavirus disease 19 infection, Phobia Ghalbe Salim model based spiritual program alone Female Iran 2020-05-23 2020-07-31 IR.LARUMS.REC.1399.001, IRCT20201003048905N1 Phase Not Applicable Completed 1 2 Months 14 Dr Behzad Rezaie, Zohreh Faramarzian 2020-10-09
Randomized, phase II clinical trial to evaluate safety and efficacy of the use of plasma from convalescent patients with the new coronavirus disease (COVID-19) for the experimental treatment of patients hospitalized in the centro medico naval 'cirujano mayor santiago tavara' Coronavirus disease 19 infection convalescent plasma alone, standard hospital treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) NAVY OF WAR OF PERU Peru 2020-09-07 CEMENA-20-01 Phase 2 Clinical Not yet recruiting 1 100 César José Suárez De Armero, José Martín Avilés Calderón, MARIO ORTIZ MONDRAGÓN, Max Grogl 2020-10-20
SALICOV: Evaluation of a Screening Program for SARS-CoV-2 Infection in the General Population Based on the Use of New Detection Approaches or for Diagnostic Orientation on Saliva Coronavirus disease 19 infection saliva sampling alone Assistance Publique Hopitaux de Paris France 2020-10-31 2021-06-30 2020-A02431-38, APHP200960, NCT04578509, SALICOV Phase Not Applicable Not yet recruiting 1 8 Months 2750 Jérôme Le Goff, Professor, LE GOFF Jérôme, Professor, Laure Choupeaux, Master, Solen Kernéis, Doctor, Solen Kernéis, MD, PhD 2020-10-12
SOGUGCOVID: Description of the Population With Genitourinary Tumors and COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Spanish Oncology Genito-Urinary Group Spain 2020-09-30 2021-10-31 NCT04578132, SOG-INM-2020-04, SOGUGCOVID Phase Not Applicable No longer recruiting 32 13 Months 250 Aránzazu González del Alba, M.D., Ph.D., Javier Puente, M.D., Ph.D., Miguel Ángel Climent, M.D., Ph.D., Natalia Vidal, M.D., Ph.D., Sergio Vázquez Estevez, M.D., Ph.D. 2020-10-12
TMPRSS2: Efficacy of Aerosol Combination Therapy of 13 Cis Retinoic Acid and Captopril for Treating Covid-19 Patients Via Indirect Inhibition of Transmembrane Protease, Serine 2 Coronavirus disease 19 infection 13 cis retinoic acid plus captopril ACE inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kafrelsheikh University Egypt 2020-11-30 2021-01-31 NCT04578236, SARS, TMPRSS2 Phase 2 Clinical Not yet recruiting 1 2 Months 360 Mahmoud Elkazzaz, B.Sc in Biochemistry, Mahmoud Elkazzaz, B.Sc,M.Sc in Biochemistry 2020-10-27
Future Health Today: A cluster randomized controlled trial of quality improvement activities in general practice Cancer, Coronavirus disease 19 infection, End stage renal disease ECHO (Extension for Community Healthcare Outcomes) education alone, Future Health Today alone, cancer FHT module alone, chronic kidney disease (CKD) FHT module alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cancer Research UK, NHMRC Clinical Trials Centre, Paul Ramsay Foundation, University of Melbourne Australia 2020-12-18 2021-08-31 2056564, ACTRN12620000993998, ANZCTR380119, U1111-1254-1693 Phase Not Applicable Not yet recruiting 2 8 Months 8000 A/Prof Jo-Anne Manski-Nankervis 2020-10-17
A phase I clinical trial for inactivated SARS-CoV-2 Vaccine(Vero Cells) Coronavirus disease 19 infection COVID-19 vaccine (inactivated/Vero cells/intramuscular, SARS-CoV-2 infection), Shenzhen Kangtai Biological Products alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Jiangsu Province Centers for Disease Control and Prevention China 2020-10-07 2022-04-06 ChiCTR2000038804 Phase 1 Clinical Not yet recruiting 2 18 Months 180 Li Guifan, Pan Hongxing 2020-10-19
A clinical trial to test the effectiveness of thalidomide in reducing immune dysfunction in covid-19 disease Autoimmune disease, Coronavirus disease 19 infection thalidomide, Celgene alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ruby Hall Clinic India 2020-10-10 CTRI/2020/10/028253 Phase 2 Clinical Not yet recruiting 1 20 Dr Abhijit R Lodha 2020-10-09
A Study to Evaluate Efficacy of Selected Homoeopathic Medicines in Prevention of COVID-19 Coronavirus disease 19 infection Variable regimens including Arsenic album , Bryonia alba , Camphora Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Ministry of Ayush India 2020-10-15 CTRI/2020/10/028280 Phase Not Applicable Not yet recruiting 1 18000 Dr Meeta Gupta, Dr Raj K Manchanda 2020-10-09
Standard of care with homoeopathy as adjuvant in COVID19 Coronavirus disease 19 infection Homoeopathic medicine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences India 2020-10-12 CTRI/2020/10/028279 Phase Not Applicable Not yet recruiting 1 128 Dr Sushma Bhatnagar 2020-10-09
COVID-19 and children with congenital heart disease Congenital heart defect, Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) All India Institute of Medical Sciences India 2020-10-15 CTRI/2020/10/028251 Phase Not Applicable Not yet recruiting 33 50 Avinash Anantharaj, C S Muthukumaran, Dr Devaprasath, Dr Dharmendra Jain, Dr Gnanasambandan, Dr H ravi Ramamurthy, Dr Harmeet Singh Arora, Dr Jabaraj, Dr Jayashree Mishra, Dr Joseph Xavier, Dr K Sivakumar, Dr Kalyanasundaram, Dr M Jayranganath, Dr Mahesh K, Dr Manoj K Rohit, Dr P V Suresh, Dr Prabhatha Rashmi Murthy, Dr Prashant Mahawar, Dr Prashant Shah, Dr Rema Devi, Dr S Ramakrishnan, Dr Saileela, Dr Sanjay Khatri, Dr Smit Shrivastava, Dr Snehal Kulkarni, Dr Srinivas Lakshmivenkateshiah, Dr Swati Garekar, Edwin Francis, K M Krishnamoorthy, Kavya Mallikarjun, Prabhatha Rashmi Murthy, Rishi Sethi, Suresh Kumar 2020-10-21
The Knowledge, Attitude And Practices related to COVID-19 in Patients Presenting to Glaucoma Clinic and the Reasons for seeking Glaucoma care Coronavirus disease 19 infection, Glaucoma Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Aravind Eye Hospital - Pondicherry India 2020-10-12 CTRI/2020/10/028278 Phase Not Applicable Not yet recruiting 1 246 Dr AnnamalaiO, Dr Kavitha S, Dr Venkatesh R, Kalluri Satya Srividya 2020-10-09
A study to evaluate the effects of stem cells in patients with acute respiratory distress syndrome caused by pneumonia due to COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia Stempeucel alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Indian Council of Medical Research, Ministry of Health and Family Welfare India 2020-10-14 CTRI/2020/10/028250, ICMR/ARDS/20-21/001 Phase 2 Clinical Not yet recruiting 2 40 Dr Geeta Jotwani, Dr Manoj Kumar Panigrahi, Dr Pawan Kumar Gupta, Dr Sharat Damodar 2020-10-09
Effect of N95 mask on general condition and respiration of health care workers Coronavirus disease 19 infection N95 FFRs alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Hamdard Institute of Medical Sciences & Research (HIMSR) India 2020-10-19 CTRI/2020/10/028249 Phase Not Applicable Not yet recruiting 1 30 Sana Yasmin Hussain 2020-10-09
PPI: Stress-free after corona: a psychological help program Acute stress disorder, Coronavirus disease 19 infection, Psychiatric disorder behaviour modification technique based intervention alone, group-based face-to-face intervention alone, home based progressive muscle relaxation exercise alone, home based work sheet exercise alone, low-threshold online digital intervention alone, model deduction intervention alone, parenting strategies based intervention alone, psychoeducation alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Humboldt University of Berlin Germany 2020-09-01 2020-35, DRKS00023220, PPI Phase Not Applicable Recruiting 1 400 Ulrike Luken 2020-10-12
A study to assess the safety and effectiveness of Thymosin alpha-1 (Talpha1) used for the treatment of Moderate to severe COVID 19 Patients Coronavirus disease 19 infection Thymosin alpha alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gufic Bioscience Ltd India 2020-10-12 CTRI/2020/10/028277, GB_THY_001_20 Phase 3 Clinical Not yet recruiting 7 120 Dr Adarsh Shetty, Dr Arti Shah, Dr Dev Nath Jha, Dr Giridhar Patil, Dr Nirhali Sonali Chandrakant, Dr Rahul Ashok Darnule, Dr S K Sonkar, DrPrachee Milind Sathe, Mr Vairamuthu Ammaiyappan 2020-10-09
Chest Radiographic Findings of Adult Patients with Confirmed Coronavirus Disease 2019 (COVID-19) at Southern Philippines Medical Center Coronavirus disease 19 infection Southern Philippines Medical Center Philippines 2020-10-01 2020-12-15 PHRR201001-002988 Phase Not Applicable Recruiting 1 2 Months Maria Theresa T. Sanchez, MD, FPCR, Nalvic De Chavez 2020-10-09
A mHealth-based randomized controlled trial for improving mental health among people living with HIV during the COVID-19 outbreak Coronavirus disease 19 infection, Depression, HIV infection Articles and audios alone, WeChat-based Cognitive-Behavior and Stress Management course alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sun Yat-Sen University China 2020-10-15 2021-12-31 ChiCTR2000038866 Phase 0 Clinical Not yet recruiting 1 14 Months Yan Guo, Yu Zeng 2020-10-09
A Randomized, Double-blind, Placebo-controlled, Phase Ib/II Clinical Study to Evaluate the Preliminary Efficacy, Safety, Pharmacokinetic Profiles and Immunogenecity of JS-016 (Recombinant Human Anti-SARS-CoV-2 Monoclonal Antibody) Given as Intravenous Infusion in Participants with Mild and Moderate COVID-19 or of SARS-CoV-2 Asymptomatic Infection Coronavirus disease 19 infection etesevimab alone COVID19 Spike glycoprotein inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) PAREXEL Clinical Research, Shanghai Junshi Biosciences Co Ltd Ukraine, Singapore, China, Russian Federation, Philippines, Hong Kong 2020-09-30 2021-06-30 2020-CT0565, JS016-002-Ib/II, PHRR201001-002968 Phase 1/Phase 2 Clinical Not yet recruiting 7 9 Months 25 Chriziel Escaño, Fatima Gugova, Joel M. Santiaguel, MD, Maria Tarcela Gler, MD 2020-10-09
Does elective orthopaedic surgery in the pandemic era increase the risk of developing COVID-19? A combined analysis of retrospective and prospective study at a national tertiary hospital in Jakarta, Indonesia Coronavirus disease 19 infection, Viral pneumonia elective orthopedic surgery alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Indonesia Indonesia 2020-07-01 2020-08-31 ChiCTR2000038865 Phase Not Applicable No longer recruiting 1 2 Months Achmad Fauzi Kamal, I Wayan Arya Mahendra Karda 2020-10-12
Study on the risk perception, mental health, and behavioural responses of university students in Hong Kong in COVID-19 pandemic Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs) Chinese University of Hong Kong China 2020-10-19 2022-12-31 ChiCTR2000038864 Phase Not Applicable Not yet recruiting 1 26 Months 600 Queenie Hoi Wing WONG 2020-10-09
MALCOV: Malaria as a risk factor for COVID-19 in western Kenya and Burkina Faso Coronavirus disease 19 infection, Plasmodium infection pyronaridine +artesunate alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Liverpool School of Tropical Medicine, London School of Hygiene and Tropical Medicine Bill & Melinda Gates Foundation, Centers for Disease Control and Prevention, Groupe de Recherche Action en Santé (GRAS), Kenya Medical Research Institute Burkina Faso, Kenya 2021-01-11 MALCOV, PACTR202009642148520 Phase 2 Clinical Not yet recruiting 4 142 Chris Drakeley, Feiko ter Kuile, Hellen Barsosio, Simon Kariuki, Sodiomo Sirima 2020-10-09
The COVID-19 Community Engagement Study Coronavirus disease 19 infection community-owned risk communication intervention alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Makerere University Uganda 2020-10-05 PACTR202010729372570 Phase Not Applicable Not yet recruiting 1 800 Daniel Semakula, Nelson Sewankambo 2020-10-09
Interobserver variability and correlation with clinical outcomes in assessing COVID-19 related chest X-ray findings using the Brixia scoring system Coronavirus disease 19 infection Philippine General Hospital Philippines 2020-06-01 2020-09-28 PHRR200929-002986 Phase Not Applicable Completed 1 3 Months Jorrel Vincent Valdez, MD, FPCR, Michelle Regina Castillo, MD, Rovi Niño D. Samedra, MD, FPCR 2020-10-12
A case report on COVID-19 inflammatory syndrome with clinical features resembling Kawasaki disease Coronavirus disease 19 infection, Kawasaki disease IVIg alone, corticosteroids alone Male Columbia University, New York Presbyterian Hospital Phase Not Applicable Status not specified 0 2 2020-10-08
A phase III clinical study to assess two-dose regimen of JNJ-78436735 compared to placebo in the treatment of patients with SARS-CoV-2 infection Coronavirus disease 19 infection JNJ-78436735 alone Johnson & Johnson Phase 3 Clinical Planned 0 2020-10-19
RELEASE: Safety Infusion of Natural Killer Cells or Memory T-Cells as Adoptive Therapy in COVID-19 Pneumonia or Lymphopenia Coronavirus disease 19 infection, Lymphocytopenia, Viral pneumonia allogeneic NK cells alone, allogeneic T memory cells alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto de Investigación Hospital Universitario La Paz Asociación Instituto de Investigación Sanitaria BioCruces, Foundation for Health Research and Biomedical Valencia, Universidad Autonoma de Madrid, Universidad Miguel Hernandez de Elche Spain 2020-09-04 2021-03-31 NCT04578210, RELEASE, RELEASE Phase 1/Phase 2 Clinical Recruiting 1 6 Months 58 Antonio Pérez Martínez, Dr, Bernat Soria, Dr, Carlos Solano, Dr, Cristina Eguizabal, Dra, Víctor Alelú Hernández, Mr 2020-10-21
CARE+: Covid-19-associated research on hand eczema in the health sector – Part 1 Coronavirus disease 19 infection, Eczema health education training alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) iDerm an der Universität Osnabrück Germany 2020-11-08 Bo/34/2020, CARE+, DRKS00022957, DRKS00022958 Phase Not Applicable Not yet recruiting 1 260 Cara Symanzik 2020-10-09
Care +: Covid-19-associated research on hand eczema in the health sector – Part 2 Coronavirus disease 19 infection, Eczema DGUV skin washer alone, lipid-containing skin cleanser alone, standard cleanser alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) iDerm an der Universität Osnabrück Germany 2021-01-04 Bo/35/2020, Care +, DRKS00022957, DRKS00022958 Phase Not Applicable Not yet recruiting 1 35 Cara Symanzik 2020-10-09
A trial to evaluate a new COVID-19 rapid test for diagnosis of COVID-19 Coronavirus disease 19 infection COVID-19 rapid test alone Graphene Leaders Canada Inc Canada Phase Not Applicable Planned 1 2020-10-08
Trial to Study the Adjuvant Benefits of Quercetin Phytosome in Patients With COVID-19 Coronavirus disease 19 infection, Inflammatory disease, Respiratory disease, Respiratory distress syndrome, Respiratory failure Quercetin Phytosome plus remdesivir COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Liaquat University of Medical & Health Sciences Pakistan 2020-10-26 2021-04-25 LUMHS/REC/894, NCT04578158 Phase 2 Clinical Not yet recruiting 1 6 Months 200 Prof. Dr. Ikram Din Ujjan, Prof. Dr. Ikram Din Ujjan, MBBS, PhD, Prof. Dr. Saeed Khan 2020-10-29
A clinical trial of HOUND COVID-19 Breathalyzer, the world's first portable breathalyzer to capture SARS-CoV-2 virus in breath of human test subjects Coronavirus disease 19 infection HOUND COVID-19 BREATHALYZER alone Hound Labs Inc Phase Not Applicable Planned 0 2020-10-16
For covid-19 infection prevention measures in sport Coronavirus disease 19 infection exercise test alone, football helmets alone Healthy volunteers accepted, Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) St Marianna University School of Medicine Japan 2020-09-09 UMIN000042034 Phase Not Applicable Not yet recruiting 1 5 Hiroto Fujiya, Ryota Muroi 2020-10-09
NeuroCovid: A Study of Intensive Care-requiring Covid-19 Patients Cognitive disorder, Coronavirus disease 19 infection, Encephalitis Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Karolinska University Hospital Karolinska Institutet Sweden 2020-08-18 2022-11-30 DNR 2020-02760, NCT04578197, NeuroCovid Phase Not Applicable Recruiting 1 27 Months 100 Lars I Eriksson, Prof, Lars I Eriksson, Professor, Mia Kivipelto, Professor 2020-10-09
CEM: Melatonin in COVID-19 Coronavirus disease 19 infection, Inflammatory disease Variable regimens including acetaminophen , hydroxychloroquine , melatonin (Elite factory) , naproxen Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Tehran University of Medical Sciences Iran 2020-08-05 CEM, IR.TUMS.VCR.REC.1399.068, IRCT20200922048804N1 Phase 2 Clinical No longer recruiting 1 20 Nastaran Keyhanian, Zahra Alizadeh, ِDr. Mohammad Ali Sahraian 2020-10-12
Health Care Worker's Perception of Patient Safety During COVID-19 Pandemic Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidad Miguel Hernandez de Elche Pontificia Universidad Catolica De Chile, Universidad Antonio Nariño, Universidad Catolica Santiago de Guayaquil, Universidad de Santander, University of Sao Paulo Spain, Chile, Colombia, Ecuador 2020-09-01 2020-12-15 2020-09, NCT04576299 Phase Not Applicable No longer recruiting 4 3 Months 800 Jose J Mira, PhD 2020-10-11
NeuroCovid: The Norwegian Study of Nervous System Manifestations and Sequelae After COVID-19 Coronavirus disease 19 infection, Psychiatric disorder anti-viral drugs therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Oslo University Hospital Haukeland University Hospital, Helse Stavanger HF, Møre and Romsdal Hospital Trust, Nordlandssykehuset HF, Ostfold Hospital Trust, Sorlandet Hospital, St Olavs Hospital, Sykehuset Innlandet HF, Sykehuset Telemark, Sykehuset i Vestfold HF, University Hospital of North Norway, University Hospital, Akershus, Vestre Viken HF Norway 2020-09-01 2023-12-31 152727, NCT04576351, NeuroCovid Phase Not Applicable Recruiting 15 40 Months 150 Anette Huuse Farmen, MD PhD, Anne Hege Aamodt, MD PhD, Anne Hege Aamodt, MD, PhD, Barbara Ratajczak-Tretel, MD, Christian Samsonsen, MD PhD, Guttorm Eldøen, MD, Hanne F Harbo, MD,PhD,Prof, Heidi Øyen Flemmen, MD, Hilde K Ofte, MD PhD, Linn H Steffensen, MD PhD, MD,PhD,Prof, Marion Boldingh, MD PhD, Martin Kurz, MD PhD Prof, Martin Weisshaar, MD, Mette Bergum, MD, Mona S E Skjelland, MD PhD Prof, Randi Eikeland, MD, Tormod Fladby, MD PhD Prof, Trine H Popperud, MD PhD, Trine H Popperud, MD, PhD, Øyvind G Torkildsen, MD PhD Prof 2020-10-08
Study to Assess the Safety of Ascending Doses of UNI-911 Inhalation in Healthy Volunteers in Preparation for Evaluation in Adults With COVID-19 Coronavirus disease 19 infection niclosamide (intranasal spray formulation, COVID-19), UNION therapeutics alone S phase kinase associated protein 2 inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) UNION therapeutics Denmark Technical University, The Danish National Advanced Technology Foundation, Trial Nation Denmark Denmark 2020-06-29 2020-12-31 NCT04576312, UNI911-101 Phase 1 Clinical Recruiting 3 6 Months 44 Mads Jellingsø, Torben Balchen, Ulf Sjöbring, MD, Wanja Nyoro 2020-10-24
A clinical study of novel and proprietary Aerosolized Delivery System (ADS) to aerosolize and deliver the KL4 surfactant noninvasively in COVID-19 patients that are at high risk of respiratory failure with an intent to avoid mechanical ventilation Coronavirus disease 19 infection Aerosurf (Aerosolized Delivery System) alone, lucinactant (aerosol), Windtree Therapeutics/ Esteve/ Lee's Pharmaceutical alone BMP10 gene inhibitor, BMP15 gene inhibitor Windtree Therapeutics Inc Phase Not Applicable Planned 0 2020-10-07
A study to fully assess the impact of KL4 surfactant on clinical endpoints such as time on mechanical ventilation, time in the ICU, mortality in COVID-19 patients who are intubated and mechanically ventilated for associated lung injury and ARDS Coronavirus disease 19 infection, Lung injury, Respiratory distress syndrome lucinactant (aerosol), Windtree Therapeutics/ Esteve/ Lee's Pharmaceutical alone BMP10 gene inhibitor, BMP15 gene inhibitor Windtree Therapeutics Inc Phase Not Applicable Status not specified 0 2020-10-09
ADVISe: Longitudinal Imaging of Microglial Activation in Different Clinical Variants of Alzheimer's Disease Alzheimers disease, Amnesia, Aphasia, Atrophy, Coronavirus disease 19 infection, Inflammatory disease 11C-ER-176 alone, Lumbar puncture alone, MK-6240-[18F] alone, MRI alone, PET scan alone, florbetaben (18F) alone Beta amyloid modulator Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Columbia University National Institute on Aging US 2020-11-01 2025-05-31 AAAS7810, ADVISe, NCT04576793, R01AG063888 Phase 2 Clinical Recruiting 1 55 Months 100 Aubrey S Johnson, William C Kreisl, MD, Zeljko Tomljanovic, MD 2020-10-09
The effect of cardiac massage training in patients with cardiac arrest with COVID-19 positioned in the ventral position Cardiac arrest, Coronavirus disease 19 infection, Respiratory disease cardiac massage training alone, chest compression alone, instructional video alone, prone position alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidade Federal de Sao Paulo - UNIFESP Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Brazil 2020-08-13 31510320.4.0000.5505, 4.016.959, RBR-2xxrrq, U111112573179 Phase Not Applicable No longer recruiting 1 1000 Comitê de Ética em Pesquisa, Elaine Peixoto Vieira Cavalcante, Juliana Lima Lopes 2020-10-12
The effect of chloroquine, hydroxychloroquine OR ivermectin in patients with severe manifestations of coronavirus Coronavirus disease 19 infection chloroquine difosfate alone, hydroxychloroquine sulfate alone, ivermectin alone Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidade Federal de Roraima Brazil 2020-05-01 30605020.7.0000.5302, 4.013.109, RBR-8h7q82 Phase 2 Clinical No longer recruiting 1 167 Allex Jardim Fonseca, ruy guilherme de souza silveira 2020-10-19
Sequelae of SAR-CoV2 infection on Quality of Life and Lung Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chulalongkorn University, Ratchadapiseksompotch Research Fund Thailand 2020-06-11 2021-06-30 TCTR20201006001 Phase Not Applicable Recruiting 1 12 Months 100 Worawan Sirichana 2020-10-09
High-Resolution Computed Tomographic (HRCT) Findings among Reverse Transcription Polymerase Chain Reaction (RT-PCR) Confirmed Coronavirus Disease 2019 (COVID-19) Adult Patients in Southern Philippines Medical Center Coronavirus disease 19 infection High-Resolution Computed Tomography alone Southern Philippines Medical Center Philippines PHRR201001-003007 Phase Not Applicable Not yet recruiting 1 Roman Aldo D. Reyes 2020-10-09
Trial for collection of blood samples from healed COVID-19 patients - research and development of in-vitro diagnostics Coronavirus disease 19 infection blood sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) R-Biopharm Ag Germany 2020-10-02 20-293, DRKS00022406 Phase Not Applicable Recruiting 1 50 Mr. Dr. med. Jan Heyckendorf, Mr. Markus Böhl 2020-10-09
Practices among anesthesiologists during COVID-19 pandemic; the risk and safety concerns Coronavirus disease 19 infection Southern Philippines Medical Center Philippines 2020-10-01 PHRR200929-002985 Phase Not Applicable Not yet recruiting 1 Alyssa Mae D. Albano 2020-10-07
Psychological Impact of Institutional Quarantine Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) PGIMER AND DR RML HOSPITAL India 2020-10-06 CTRI/2020/10/028194 Phase Not Applicable Not yet recruiting 1 100 Pragya Sharma 2020-10-08
Risk Factors and Computed Tomography Findings in COVID-19 Adult respiratory distress syndrome, Coronavirus disease 19 infection, Viral pneumonia Siemens 256-slice multidetector tomograph (SOMATOM) alone, chest computed tomography (CT) scan alone Instituto Nacional de Cardiologia Ignacio Chavez Mexico 2020-04-01 2020-10-01 20-1177, NCT04577105 Phase Not Applicable Completed 1 6 Months 233 Maria Elena Soto, MsC and PhD, Sergio Andres Criales Vera, MD 2020-10-08