Last updated: Nov 07, 2020 - 02:00 GMT

Title Indication Intervention Actions PatientSelection Sponsor Collaborator Country StartDate EndDate Identifiers Phase Recruitment Status Sites Trial Duration Enrollment Count Contacts LastChanged
Ampligen in Chronic Fatigue Syndrome Chronic fatigue syndrome, Coronavirus disease 19 infection rintatolimod alone 2,5-Oligoadenylate synthetase stimulator, Interferon type I receptor agonist, Ribonuclease stimulator, TLR-3 agonist Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) AIM ImmunoTech Inc US AMP 511, NCT00215813 Phase 3 Clinical Recruiting 2 Ann Marie Coverly, Charles Lapp, MD, Charles W. Lapp, M.D., Daniel Peterson, M.D., Daniel Peterson, MD, Diane Young 2020-10-27
Online MBI for Families Affected by PPDA Anxiety disorder, Coronavirus disease 19 infection, Depression mindfulness-based cognitive therapy alone, mindfulness-based stress reduction program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Children's & Women's Health Centre of British Columbia (C&W) Canada 2020-10-20 2022-08-31 H20-01884, NCT04617132 Phase Not Applicable No longer recruiting 0 22 Months 40 Katarina Tabi, S. Evelyn Stewart 2020-11-06
Prevalence of Thrombosis in COVID-Patients Coronavirus disease 19 infection, Thrombosis Duplex ultrasound alone, blood test alone, cognitive test alone, smelling test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Klinikum Augsburg Germany 2020-11-04 2021-06-30 COVID THROMBOSE, NCT04615026 Phase Not Applicable Recruiting 0 7 Months 400 Alexander Hyhlik-Duerr, MD, Yvonne Gosslau, MD 2020-11-06
SUMMIT: Scaling Up Maternal Mental Health Care by Increasing Access to Treatment Anxiety disorder, Coronavirus disease 19 infection, Depression TelePsychiatry Program alone, manualized behavioral activation treatment alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mount Sinai Hospital Harvard Medical School, NorthShore University HealthSystem (NorthShore), Patient Centered Outcome Research Institute, St Michaels Hospital, Sunnybrook Health Sciences Centre, University of Colorado, Boulder, University of North Carolina, Women's College Hospital US, Canada 2020-01-06 2025-12-30 NCT04153864, PCS-2018C1-10621, SUMMIT Phase Not Applicable Recruiting 0 71 Months 1368 Anastasia Harris, Cindy-Lee Dennis, Daisy R Singla, PhD, Holly Krohn, Maria Michalowska, Richard K Silver, MD, Samantha Meltzer-Brody, MD, MPH, Simone Vigod 2020-11-06
An observational, retrospective, single-center study to determine the efficacy and safety of tocilizumab in patients with severe COVID-19 infection Coronavirus disease 19 infection tocilizumab alone Albert Einstein Healthcare Network Phase Not Applicable Status not specified 0 66 2020-11-06
ENSEMBLE 2: A Study of Ad26.COV2-S for the Prevention of SARS-CoV-2-mediated COVID-19 in Adults Coronavirus disease 19 infection JNJ-78436735 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Janssen Vaccines & Prevention BV Colombia, Belgium, Philippines, France, South Africa, UK, Germany, Spain, US 2020-11-06 2023-05-10 2020-003643-29, CPMS 46804, CR108916, ENSEMBLE 2, IRAS 288552, NCT04614948, VAC31518COV3009 Phase 3 Clinical Recruiting 26 30 Months 30000 Janssen Vaccines & Prevention B.V. Clinical Trial, Mr Malcolm Macartney, Ms Shola Ayeni, Study Contact 2020-11-06
FX-COVID: FX-06 to Rescue Acute Respiratory Distress Syndrome During Covid-19 Pneumonia Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia FX-06 alone Cadherin-5 modulator, Factor Ia modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-11-30 2021-07-31 2020-002056-20, APHP200495, FX-COVID, NCT04618042 Phase 2 Clinical Not yet recruiting 1 8 Months 50 BRECHOT Nicolas, MD, David HAJAGE, MD, Nicolas BRECHOT, MD 2020-11-06
An observational study to evaluate the correlation between complement activation and disease severity in patients hospitalized with COVID-19 Coronavirus disease 19 infection Apellis Pharmaceuticals Inc Phase Not Applicable Status not specified 0 41 2020-11-06
Analysis of the immunological response to coronavirus infection Coronavirus disease 19 infection Healthy volunteers accepted The University of Birmingham Department of Health and Social Care, Medical Research Council UK 2020-04-01 2025-06-05 CPMS 46588, IRAS 282164, RG_20-038 COVID-19, ISRCTN63911163 Phase Not Applicable Recruiting 4 62 Months 600 Dr Rachel Bruton, Prof Paul Moss 2020-11-06
SEMPATICO: Semaglutide to Reduce Myocardial Injury in Patients With COVID-19 Coronavirus disease 19 infection, Heart injury semaglutide (subcutaneous, diabetes/obesity/NASH), Novo Nordisk alone, standard of care alone Glucagon-like peptide 1 receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The University Health Network Canadian Institutes of Health Research, St Michaels Hospital, University of Toronto Mexico, UK, Canada, Brazil 2020-11-30 2022-03-31 NCT04615871, SEMPATICO, UHNSEMPATICO1 Phase 2 Clinical Not yet recruiting 10 16 Months 400 Andrei C Sposito, MD, Anil Gupta, MD, Beatriz Villegas, DDS, Carlos Fernando, Cheryl Geen-Smith, Daniela M Rosiles, MD, Eduardo Mateos, MD, Emily McDonald, MD, Gina Dutton, Jorge Escobedo, MD, Juan A Santillan, MD, Julieta Valenzuela, MD, Kim Connelly, MD, Mansoor Husain, MD, Priscilla Griffo, Rodrigo B Esper, MD, Sarah Elsayed, Ticiane Bovi, Vinoda Sharma, MD, Vladimir Dzavik, MD, Vladimír Džavík, MD 2020-11-06
IMMUNO-COVID19: Hyperimmune Plasma for Patients With COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome hyperimmune plasma alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ospedale Papa Giovanni XXIII Italy 2020-07-02 2022-07-02 IMMUNO-COVID19, IMMUNO-COVID19, NCT04614012 Phase Not Applicable Recruiting 1 24 Months 100 ANNA FALANGA, Anna Falanga 2020-11-06
PanDirect: Self-care Tools and Telephone Coaching for Depression and Anxiety During Pandemics Anxiety disorder, Coronavirus disease 19 infection, Depression lay telephone coaching alone, self-care tool alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) St. Mary's Research Center Canada 2020-10-21 2021-05-01 NCT04609371, PanDirect, SMHC-20-10 Phase Not Applicable Not yet recruiting 1 6 Months 176 Mark Yaffe, Study coordinator 2020-11-06
Food: A Three-Arm Study Examining Food Insecurity Interventions Breast tumor, Coronavirus disease 19 infection home grocery delivery alone, medically-tailored hospital-based food pantry access alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Memorial Sloan-Kettering Cancer Center Columbia University, Jacobi Medical Center, Lincoln Medical and Mental Health Center, Montefiore Health System, Queens Cancer Center of Queens Hospital, Roswell Park Comprehensive Cancer Center, St. Barnabas Medical Center, The Brooklyn Hospital Center US 2012-05-08 2022-05-31 12-099, Food, NCT01603316 Phase 2 Clinical Recruiting 7 120 Months 668 Caroline Hwang, MD, Francesca Gany, MD, MS, Francesca Gany, MD, PhD, Ilmana Fulger, MD, Jennifer Leng, MD, MPH, Tarek Elrafei, D.O. 2020-11-06
MIND-VR: Virtual Reality for COVID-19 Operators' Psychological Support Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection virtual reality-based protocol alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Fondazione IRCCS Istituto Neurologico Carlo Besta University of Milano-Bicocca Italy 2020-11-01 2021-11-01 MIND-VR, MIND-VR/BESTA, NCT04611399 Phase Not Applicable Not yet recruiting 1 12 Months 90 Eleonora F Orena, PhD, Federica Pallavicini, PhD 2020-11-06
Evaluation of antibody and cytokine detection in tears of COVID-19 patients Coronavirus disease 19 infection Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Postgraduate Institute of Medical Education and Research India 2020-11-10 CTRI/2020/11/028813 Phase Not Applicable Not yet recruiting 1 120 Reema Bansal 2020-11-06
AFFORD COVID: Asthma in Families Facing Out-of-pocket Requirements Due to COVID-19 Asthma, Coronavirus disease 19 infection AAFA's chat bot insurance navigation alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Harvard Pilgrim Health Care Asthma and Allergy Foundation of America, Harvard TH Chan School of Public Health, Patient Centered Outcome Research Institute, University of North Carolina US 2020-11-02 2023-01-31 AFFORD COVID, IHS-1602-34331, NCT04613739 Phase Not Applicable Not yet recruiting 1 26 Months 430 Alison Galbraith, MD, MPH, Lauren Cripps, MS 2020-11-06
Yoga program on COVID-19 patients Acute stress disorder, Coronavirus disease 19 infection integrated biofeedback based yoga program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Central Council for Research in Yoga and Naturopathy, Ministry of Ayush India 2020-11-04 CTRI/2020/11/028827 Phase Not Applicable Not yet recruiting 6 86 Dr Amit Agarwal, Dr Chhavi Gupta, Dr Deepak KK, Dr Minakshi Dhar, Dr Raghavendra Rao M, Dr Sudheer, Dr Sunitha Mondal 2020-11-06
CRI:SIS: COVID-19 Responsive Intervention: Systems Improvement Simulations (CRI:SIS) Randomized, Control Trial Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection Simulation intervention alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Yale University Agency for Healthcare Research and Quality US 2020-11-15 2022-11-15 1R01HS028340-01, 2000029372, CRI:SIS, NCT04614844 Phase Not Applicable Not yet recruiting 1 24 Months 84 Ambrose H Wong, MD, MSEd, Ambrose Wong, MD, MSEd, Leigh Evans, MD, Leigh V. Evans, MD 2020-11-06
Finding Wellness in the Pandemic Acute stress disorder, Alcoholism, Coronavirus disease 19 infection, Drug dependence trauma Informed Psychotherapy alone, trauma Informed Yoga alone Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) The University Of Lethbridge Canada 2020-11-01 2021-04-30 2020-096, NCT04615741 Phase Not Applicable Not yet recruiting 1 6 Months 200 Cheryl Currie 2020-11-06
SeroCovid < 19: A Prospective, COVID-19, Seroconversion Study in a Tertiary Pediatric Patient Cohort Cardiovascular disease, Coronavirus disease 19 infection SARS-CoV-2 serological assessment alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Universitair Ziekenhuis Gent Universitaet Gent Belgium 2020-10-29 2021-11-01 BC-08104, NCT04615000, SeroCovid < 19 Phase Not Applicable Recruiting 1 12 Months 1000 Filomeen Haerynck, MD, PhD, Levi Hoste, MD 2020-11-06
Understanding Reactions to Emotional Material in the Media During COVID-19 Coronavirus disease 19 infection, Psychiatric disorder Tetris game alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Uppsala University Sweden 2020-10-28 2021-01-15 2020-03991, NCT04608097 Phase Not Applicable Recruiting 1 2 Months 66 Emily Holmes, Prof, Laura Singh, PhD 2020-11-06
PACBACK: Spinal Manipulation and Patient Self-Management for Preventing Acute to Chronic Back Pain Coronavirus disease 19 infection, Lower back pain Spinal manipulation therapy alone, Supported-self management program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Minnesota Duke University, Oregon Health Sciences University, University of North Texas, University of Pittsburgh, University of Washington US 2018-10-25 COVID19_IMPACT, CSH-2018-26524, NCT03581123, PACBACK Phase 3 Clinical Suspended 3 1180 Gert Bronfort, PhD, DC 2020-11-06
Role of Physiotherapist in enhancing functional aerobic capacity in pulmonary rehabilitation in Covid-19 Patients Coronavirus disease 19 infection, Viral pneumonia pulmonary rehabilitation program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Apollo Hospitals Educational Research Foundation Indraprastha Apollo Hospital India 2020-11-07 CTRI/2020/11/028811 Phase Not Applicable Not yet recruiting 1 50 Seema Grover 2020-11-06
Side effects of drugs used in ICU Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Government Institute of Medical Sciences, Greater Noida India 2020-11-13 CTRI/2020/11/028800 Phase Not Applicable Not yet recruiting 1 100 Dr Nazia Nazir 2020-11-06
The study of psychological interventions either individually or in groups and comparing its effect in reduction of psychological distress in covid-19 positive patients Acute stress disorder, Coronavirus disease 19 infection individual psychotherapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) HBTMC and Dr RN Cooper Municipal General Hospital India 2020-11-02 CTRI/2020/11/028799 Phase Not Applicable Not yet recruiting 1 55 Dr Deoraj sinha, Dr Tejaswini Miskin 2020-11-06
Effect of SARS-CoV-2 Equine Antiserum Immunoglobulin (Purified F[ab]2 fragment) in hospitalized COVID-19 patients with moderate disease Coronavirus disease 19 infection Equine antisera Immunoglobulin (Purified F[ab]2 fragment) alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Biological E Ltd India 2020-11-05 BECT063/Equine.CoV.Ab-Phase-I/CTP-01Ver: 1.1, CTRI/2020/11/028779 Phase 1 Clinical Not yet recruiting 2 72 Dr Chandramani Singh, Dr Kishore TSA, Dr Subhash Thuluva, Dr Venugopal 2020-11-06
Effect of COVID-19 on physical activity, screen time and emotional wellbeing on medical students Coronavirus disease 19 infection Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs) Sawai ManSingh Medical College India 2020-11-02 CTRI/2020/10/028744 Phase Not Applicable Not yet recruiting 1 200 Dr Anuradha Yadav 2020-11-06
HiFlo-COVID: High-Flow Nasal Cannula in Severe COVID-19 With Acute Hypoxemic Respiratory Failure Coronavirus disease 19 infection, Hypoxia, Respiratory failure High flow nnasal cannula oxygen therapy alone, High-flow nasal cannula alone, oxygen alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundacion Clinica Valle del Lili Colombia 2020-08-11 2021-07-28 001635, HiFlo-COVID, NCT04609462 Phase 2 Clinical Recruiting 1 11 Months 196 Gustavo A. Ospina Tascón, MDPhD, Sergio I. Prada, MPA PhD 2020-11-06
A phase III trial to evaluate the efficacy of recombinant new coronavirus vaccine (CHO cell) for the prevention of SARS-CoV-2 infection Coronavirus disease 19 infection SARS-CoV-2 protein subunit vaccine (COVID-19), Chongqing Zhifei Biological Products/ Institute of Microbiology, Chinese Academy of Sciences alone COVID19 Spike glycoprotein modulator Chongqing Zhifei Biological Products Co Ltd, Institute of Microbiology, CAS Phase 3 Clinical Planned 0 2020-11-06
Application of an intelligent mobile isolation operating cabin preventing COVID-19 infection Coronavirus disease 19 infection coronary angiography alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Beijing Tsinghua Chang Gung Hospital Tsinghua University China 2020-11-30 2021-11-29 ChiCTR2000039640 Phase 0 Clinical Recruiting 0 12 Months 10 Boda Zhou, Ping Zhang 2020-11-06
A Medical Records Based Study for noninvasive ventilation in patients with coronavirus disease 2019 (COVID-19) related acute hypoxemic respiratory failure Coronavirus disease 19 infection, Hypoxia, Respiratory failure Shenzhen People's Hospital China 2020-10-19 2020-11-13 ChiCTR2000039567 Phase Not Applicable Recruiting 0 40 Rongchang Chen, Yingyun Fu 2020-11-06
A study to evaluate the clinical effect of arbidol combined with adjuvant therapy in patients with COVID-19 Coronavirus disease 19 infection adjuvant therapy alone, arbidol alone Jiaxing University China Phase 2 Clinical Status not specified 1 62 2020-11-06
LKPCOVID19: Level of Knowledge and Preparedness for COVID-19 Pandemic Among Government Dental Officers in Perak, Malaysia: A Cross Sectional Study Coronavirus disease 19 infection Healthy volunteers accepted Taiping Hospital Malaysia 2020-11-18 2020-12-18 HSR2020-01 56920, LKPCOVID19, NMRR-20-2367-56920 Phase Not Applicable Not yet recruiting 1 1 Month 509 Dr FATIN ASHIKIN BINTI ABDUL MUTALIB 2020-11-06
DETECT: A clinical study to assess the use of wearable fitness devices for the early identification of COVID infection Coronavirus disease 19 infection Fitbit alone, wearable fitness device alone Scripps Research Institute US 2020-03-25 DETECT Phase Not Applicable Recruiting 1 100000 Jennifer Radin, PhD 2020-11-05
RaDiCo: PCR and Rapid Diagnostic Test on Saliva and Nasopharyngeal Swabs for the Detection of SARS-CoV-2 Coronavirus disease 19 infection AAZ-LMB (COVID-VIRO) alone, Panbio COVID-19 Ag (Abbott) alone, Standard Q COVID-19 (Roche) alone, polymerase chain reaction alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Lausanne Centre Hospitalier Universitaire Vaudois Switzerland 2020-09-25 2020-12-31 2020-02269, NCT04613310, RaDiCo Phase Not Applicable Recruiting 1 3 Months 1250 Blaise Genton, MD PhD, Blaise Genton, MD, PhD, MPH, Blaise Genton, MD-PhD, Gilbert Greub, MD, PhD, Valerie D'Acremont, MD-PhD, Valérie D'Acremont, MD PhD 2020-11-05
An academic trial to study the prophylactic activity of Vishasura Kudineer (VSK) in healthcare workers exposed/non-exposed to COVID-19 patients Coronavirus disease 19 infection VSK decoction alone, Vishasura Kudineer (VSK), a Siddha formulation alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Ministry of Ayush India 2020-11-12 CTRI/2020/11/028905 Phase 1/Phase 2 Clinical Not yet recruiting 1 120 Dr K Prasanna Purna, Dr Sivakumar Vijayaraghavalu 2020-11-06
Telephonic intervention for people tested positive for Covid Coronavirus disease 19 infection tele counselling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Yenepoya medical college hospital India 2020-11-09 CTRI/2020/11/028903 Phase Not Applicable Not yet recruiting 1 Jeyaram 2020-11-06
To Evaluate the Efficacy and Safety of ANT-V Syrup to Show Antiviral Action of Upper Respiratory Tract Like Common Cold and Act as an Immune Booster to Fight Against Infection, Flu, Fever, Sore Throat, Nasal and Chest Congestion Breathlessness in COVID-19 Patients Common cold, Coronavirus disease 19 infection, Upper respiratory tract infection ANT-V syrup alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Bhargava Phytolab Limited India 2020-11-16 CTRI/2020/11/028897 Phase 3 Clinical Not yet recruiting 1 60 Dr Rahul Singh, Pragya Singh 2020-11-06
Frailty Assessment for COVID-19 Severity Aging, Coronavirus disease 19 infection Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences India 2020-11-09 CTRI/2020/11/028885 Phase Not Applicable Not yet recruiting 1 100 Yudhyavir Singh 2020-11-06
Cancer Services during COVID-19 Pandemic – Importance of a Symptoms Based Screening Strategy Cancer, Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences India 2020-11-11 CTRI/2020/11/028859 Phase Not Applicable Not yet recruiting 1 400 Akash Kumar 2020-11-06
Lifestyle and psychological Changes During COVID 19 Lockdown Among Undergraduate Students in Chennai Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs) Sri Ramachandra Institute of Higher Education and Research India 2020-11-16 CTRI/2020/11/028848 Phase Not Applicable Not yet recruiting 1 526 Dr Akila GV 2020-11-06
A study on knowledge, attitude and behavior of healthcare workers on practices required to prevent COVID - 19 Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Shree Krishna Hospital, pramukhswami medical college India 2020-11-11 CTRI/2020/11/028846 Phase Not Applicable Not yet recruiting 1 200 Chirag Modi 2020-11-06
Outcomes of Nutrition scores on serious COVID patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Vardhman Mahavir Medical College & Safdarjung Hospital India 2020-11-09 CTRI/2020/11/028843 Phase Not Applicable Not yet recruiting 1 78 Saurav Mitra Mustafi, Saurav Mitra mustafi 2020-11-06
ERT-P: Emotion Regulation Training Via Telehealth During the COVID-19 Pandemic Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression emotion regulation training alone, internet-based online platform alone, videoconferencing software alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Teachers College, Columbia University University of Michigan US 2020-05-01 2023-01-31 20-269, ERT-P, NCT04615416 Phase Not Applicable Recruiting 1 33 Months 100 Douglas S Mennin, Ph.D., Douglas S Mennin, PhD 2020-11-06
Correlating the Clinical and CT Severity of COVID-19 Patients with the Inflammatory Markers and Co-morbidities Coronavirus disease 19 infection CB-NAAT alone, CT Thorax alone, GeneXpert alone, RT-PCR alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sri Ramachandra University Sri Ramachandra Institute of Higher Education and Research India 2020-11-15 CTRI/2020/11/028836 Phase Not Applicable Not yet recruiting 1 200 Aparna Ganesh, Preetam Arthur 2020-11-06
Clinical evaluation of STANDARD Q COVID-19 Ag Test Coronavirus disease 19 infection STANDARD Q COVID-19 Ag test alone Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) SD Biosensor Inc India 2020-10-30 CTRI/2020/10/028774 Phase Not Applicable Not yet recruiting 1 500 Dr Niraj Kothari 2020-11-06
Screening for COVID-19 Coronavirus disease 19 infection breath acoustic analysis alone, breathing sounds analysis algorithm alone, iPhone app (ID Fusion Software, Inc) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Manitoba Natural Sciences and Engineering Research Council of Canada Canada 2020-11-15 2021-12-30 B2020:070 (HS24165), NCT04615208 Phase Not Applicable Not yet recruiting 1 13 Months 200 Mari Garcia, M.Sc., Zahra Moussavi, Ph.D. 2020-11-06
An observational study on the levels of IL-6 early after tocilizumab to distinguish survivors from non-survivors in COVID-19 pneumonia Coronavirus disease 19 infection, Pneumonia tocilizumab alone Azienda Ospedaliero-Universitaria di Udine Phase Not Applicable Status not specified 0 24 2020-11-05
FVR: Efficacy and Safety of Favipiravir in Covid-19 Patients in Indonesia Coronavirus disease 19 infection Standard of care alone, azithromycin plus favipiravir RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) INA-RESPOND Secretariat National Institute Of Health Research & Development (Nihrd)- Ministry Of Health Of The Republic Of Indonesia Indonesia 2020-10-15 2020-12-31 FVR, FVR, NCT04613271 Phase 3 Clinical Recruiting 3 2 Months 210 Dr Harli Amir Mahmudji, Dr Harli Amir Mahmudji, SpPD KEMD, Dr. dr. Armedy Ronny Hasugiana, M. Biomed, MD, dr. Adria Rusli, Sp.P, dr.Sofyan Budi Raharjo, SpP FISR 2020-11-06
Ketogenic Diet as Protective Factor During COVID-19 Coronavirus disease 19 infection ketogenic diet with phytoextract alone, low carbohydrate diet alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Padova San Bortolo Hosp Italy 2020-11-01 2021-08-30 KDSARS0120, NCT04615975 Phase Not Applicable Recruiting 1 9 Months 28 Antonio Paoli, MD, Lorenzo Cenci, MD 2020-11-06
E-COCCON: Effect of COVID-19-related Containment in Children Coronavirus disease 19 infection, Post traumatic stress disorder Children (6-12 yrs), Adolescents (13-17 yrs) Centre Hospitalier Universitaire de Toulouse France 2020-06-10 2020-11-30 E-COCCON, NCT04615195, RC31/20/0205 Phase Not Applicable Recruiting 1 5 Months 1000 AURIOL Françoise, PhD, CLAUDET Isabelle, Pr, Françoise Auriol, PhD, Isabelle CLAUDER, Pr, Isabelle CLAUDET, Pr 2020-11-06
IVIG in Patients With Severe COVID-19 Requiring Mechanical Ventilation Coronavirus disease 19 infection Octagam alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sharp HealthCare US 2020-11-01 2021-06-30 2010902, COVID-IVIG VENT, NCT04616001 Phase 4 Clinical Not yet recruiting 1 8 Months 10 George Sakoulas, MD, Kathryn Miller, Matthew Geriak, PharmD 2020-11-06
Squalene and COVID-19 Coronavirus disease 19 infection Variable regimens including chloroquine phosphate , hydroxychloroquine , lopinavir + ritonavir , microemulsion containing extracted squalene , ribavirin HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mashhad University of Medical Sciences Iran 2020-10-31 IR.MUMS.REC.1399.468, IRCT20200927048848N2 Phase 3 Clinical Recruiting 1 15 Deputy of Research and Technology, Mahmood Ebrahimi 2020-11-05
Recovery Profiles in Patients With SARS-CoV-2 Outcomes Undergoing Rehabilitation Coronavirus disease 19 infection, Psychiatric disorder comprehensive intensive rehabilitation alone, early rehabilitation alone, home mindfulness training alone, personalized ambulatory walking exercise alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Azienda Ospedaliero-Universitaria di Ferrara Italy 2020-03-30 2021-06-03 COVID19_REHABILITATION, NCT04615390 Phase Not Applicable Recruiting 1 14 Months 200 Alessandra Botti, MD, Anna Scotti, MD, Antonella Occhi, PT, Dino De Filippo, MD, Elisabetta Antiga, MD, Fabio Manfredini, MD, PhD, Francesca Filippini, PT, Francesco Baldasso, MD, Giada Milani, PsyD, PhD student, Giulia Bellon, MD, Giulia Dallagà, PsyD, Ilaria Ferioli, PT, Nicola Lamberti, PhD, Silvia Mottaran, PT, Sofia Straudi, Sofia Straudi, MD, PhD, Susanna Lavezzi, MD 2020-11-05
A phase III clinical trial of MP-0420 for the potential treatment of COVID-19 infection Coronavirus disease 19 infection MP-0420 alone Angiotensin converting enzyme 2 inhibitor, COVID19 Spike glycoprotein inhibitor Molecular Partners AG Novartis AG Phase 3 Clinical Planned 0 2020-11-05
A phase II clinical trial of MP-0420 for the potential treatment of COVID-19 infection Coronavirus disease 19 infection MP-0420 alone Angiotensin converting enzyme 2 inhibitor, COVID19 Spike glycoprotein inhibitor Molecular Partners AG Novartis AG Phase 2 Clinical Planned 0 2020-11-05
HFP: Home Fitness Project Coronavirus disease 19 infection exercise program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Kyoto University Japan 2020-10-30 HFP, UMIN000042340 Phase Not Applicable Recruiting 1 100 Norio Watanabe, Takashi Ishida 2020-11-06
Effect of Iranian Borage on the management of Covid-19 symptoms Coronavirus disease 19 infection Iranian borage aerial part alone, routine treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shiraz University of Medical Sciences Iran 2020-11-07 IR.SUMS.REC.1399.015, IRCT20201016049048N1 Phase 0 Clinical Not yet recruiting 1 60 Ali Sahragard, Dr. Abbas Rezaeian zadeh, Mohammad Mehdi Zarshenas, Mohammad mehdi Zarshenas 2020-11-06
A phase II, randomized, open-label, two-arm study of silmitasertib versus standard of care or supportive care in the treatment of patients with moderately ill COVID-19 penumonia infection Coronavirus disease 19 infection, Viral pneumonia silmitasertib alone Casein kinase II inhibitor Senhwa Biosciences Inc Georgia, US Phase 2 Clinical Not yet recruiting 2 20 Dr Christopher P Recknor 2020-11-06
CardiolRx in Patients With COVID-19 and Cardiovascular Disease or Risk Factors Cardiovascular disease, Cerebrovascular disease, Coronavirus disease 19 infection, Diabetes mellitus, Hypertension, Obesity, Peripheral vascular disease cannabidiol (nanoformulation/subcutaneous, heart failure), Cardiol Therapeutics alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cardiol Therapeutics Inc US 2020-12-31 2021-09-30 CARDIOL 100-03, NCT04615949 Phase 2/Phase 3 Clinical Not yet recruiting 1 9 Months 422 Andrea B Parker, PhD, Dennis McNamara, MD, Dr. Arvind Bhimaraj, Dr. Barry Trachtenberg, Dr. Carsten Tschöpe, Dr. Leslie Cooper, Dr. Matthias Friedrich, Dr. Peter Liu, Dr. Wilson Tang, Eldon R Smith, MD 2020-11-06
VOC-COVID-Diag: Analysis of Volatile Organic Compounds in Exhaled Air and in Sweat in the Context of Suspicion of COVID-19 Infection Coronavirus disease 19 infection canine odor detection alone, electronic nose alone, mass spectrometry alone, volatile organic compound analysis alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopital Foch France 2020-10-21 2021-10-31 2020_0143, NCT04614883, VOC-COVID-Diag Phase Not Applicable Recruiting 1 12 Months 100 Elisabeth Hulier-Ammar, PhD, Helene Salvator, MD, Hélène Salvator, MD, Philippe Devillierr, MD PhD 2020-11-05
HOPE: The digital Hope program for people living with cancer during COVID-19 Cancer, Coronavirus disease 19 infection HOPE program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Coventry University UK 2020-03-31 2020-09-02 HOPE, IRRID: RR1-10.2196/24264, ISRCTN79623250 Phase Not Applicable Completed 2 5 Months 40 Dr Hayley Wright, Prof Turner 2020-11-06
An observational study to determine tocilizumab treatment for cytokine release syndrome in hospitalized patients with Coronavirus Disease 2019 Coronavirus disease 19 infection, Systemic inflammatory response syndrome tocilizumab alone Yale University Phase Not Applicable Status not specified 0 239 2020-11-06
Cov-Peru: Efficacy, Safety and Immunogenicity of Inactivated SARS-CoV-2 Vaccines (Vero Cell) in Healthy Adult Population In Peru Coronavirus disease 19 infection COVID-19 vaccine (inactivated, Vero cells/intramuscular), Beijing Biological Products Institute/National Institute for Viral Disease Control and Prevention of Chinese Center for Disease Control and Prevention alone, COVID-19 vaccine (inactivated, Vero cells/intramuscular), Wuhan Institute of Biological Products/Wuhan Institute of Virology, CAS alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidad Peruana Cayetano Heredia Universidad Nacional Mayor de San Marcos Peru 2020-09-10 2021-09-01 Cov-Peru, NCT04612972, UPERUANACH Phase 3 Clinical Recruiting 1 11 Months 6000 German Malaga, MD, Hugo García, PhD 2020-11-05
Lung Function, Exercise Capacity, and Serology Responses in Patients With COVID-19 Coronavirus disease 19 infection remdesivir alone, Variable regimens including interferon beta-1b , lopinavir + ritonavir , ribavirin COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, HIV protease inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chinese University of Hong Kong Health and Health Services Research Fund, The University of Hong Kong Hong Kong 2020-05-22 2022-05-21 2020.229, NCT04611243 Phase Not Applicable Recruiting 1 24 Months 80 David S Hui, MD, Karen Yiu, BSc, Susanna Ng, MBChB, Susanna So-Shan Ng 2020-11-06
COVID-19: Health-Related Quality of Life of Patients With Asthma During the Pandemic of COVID-19 Asthma, Coronavirus disease 19 infection, Lung disease Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cairo University Egypt 2020-05-01 2021-03-01 COVID-19, NCT04613245, SERIAL 39-2020 Phase Not Applicable Recruiting 1 10 Months 400 Naglaa Youssef, Youssef 2020-11-05
Clinical study on the efficacy and safety of Jieyuwan in the treatment of epidemic stress, anxiety and depression (stagnation of liver Qi syndrome) Anxiety disorder, Coronavirus disease 19 infection, Depression, Viral pneumonia Jieyuwan pill alone, psychological support therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Dongfang Hospital Tiansheng Pharmaceutical Group Co Ltd China 2020-11-15 2021-10-15 ChiCTR2000039536 Phase 4 Clinical Not yet recruiting 1 11 Months 390 Rongjuan Guo, Tian'ge Lu 2020-11-06
A Randomized, Placebo-Control Trial to Evaluate the Efficacy of Xylitol Nasal Spray Coronavirus disease 19 infection Xlear, Xlear Inc alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Larkin Community Hospital Ferrer Medical Innovations Llc, Xlear Inc US 2020-08-08 2021-08-08 LCH-3-082020, NCT04610801 Phase 3 Clinical Recruiting 2 12 Months 200 CAMILLE GO, Camille Celeste Go, M.D., Camille Go, MD, Gustavo Ferrer, M.D, Marcos Sanchez-Gonzalez, Marcos Sanchez-Gonzalez, MD 2020-11-06
PExCoV: Therapeutic Plasma Exchange as an Adjunctive Strategy to Treat Coagulopathy and Inflammation in Severe Covid-19 Blood clotting disorder, Coronavirus disease 19 infection, Inflammatory disease, Respiratory failure plasma exchange alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Zurich 2020-12-31 2021-12-31 NCT04613986, PExCoV, SD01 Phase Not Applicable Not yet recruiting 0 12 Months 20 2020-11-05
A phase IIa proof-of-concept study to evaluate safety and initial efficacy of AS-1411 for the treatment of COVID-19 Coronavirus disease 19 infection AS-1411 alone BCL2 gene inhibitor, Nucleolin inhibitor Qualigen Therapeutics Inc 2021-07-31 Phase 2a Clinical Planned 0 2020-11-04
COV2020: Medical-biological Research of the Pathogenesis of COVID-19 Disease Caused by SARS-CoV-2 Coronavirus disease 19 infection PCR testing alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Burnasyan Federal Medical Biophysical Center, Federal Research Clinical Center of Federal Medical and Biological Agency Russian Federation 2020-07-21 2022-12-31 COV2020, COV2020, NCT04611841 Phase Not Applicable Recruiting 1 29 Months 250 Vadim Govorun, MD 2020-11-06
SATICOVID19: Clinical Characteristics and Outcomes of Patients With COVID-19 on Mechanical Ventilation in Argentina Coronavirus disease 19 infection Mechanical ventilation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Argentina 2020-04-30 2020-11-15 NCT04611269, SATI, SATICOVID19 Phase Not Applicable Recruiting 5 6 Months 800 Arnaldo Dubin, MD, Cecilia I Loudet, MD, Elisa Estenssoro, MD, Maria G Saenz, MD, Rosa Reina, MD, Vanina Kanoore Edul, MD 2020-11-05
Randomized, controlled trial to test the (cost)effectiveness of step-by-step, a smartphone-based self-help program for Syrian refugees in Egypt Acute stress disorder, Coronavirus disease 19 infection Step By Step app alone, information based treatment as usual alone, smartphone and internet-based self-help program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Berlin Free University EU Horizon 2020 Egypt 2020-12-01 2020-2021-009, DRKS00023505 Phase 2 Clinical Not yet recruiting 1 532 Sebastian Burchert 2020-11-04
A Study Looking at the Efficacy, Immune Response, and Safety of a COVID-19 Vaccine in Adults at Risk for SARS-CoV-2 Coronavirus disease 19 infection NVX-CoV2373 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Novavax Inc US Department of Health and Human Services, US Government Puerto Rico, US, Mexico 2020-11-30 2022-12-30 2019NCOV-301, NCT04611802 Phase 3 Clinical Not yet recruiting 110 25 Months 30000 Kristin Ciccarelli, Lisa M Dunkle, MD 2020-11-05
SeCoBelChild: Sero-prevalence COVID-19 Among Belgian Children Coronavirus disease 19 infection Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs) Sciensano Katholieke Universiteit Leuven, McGill University 2020-11-20 2021-08-31 NCT04613817, SC_044A, SeCoBelChild Phase Not Applicable Not yet recruiting 0 9 Months 1640 Els Duysburgh, MD, MPH, PhD, Melissa Vermeulen, MD 2020-11-05
A clinical trial of IMS-001 for the treatment of COVID-19 and  acute respiratory distress syndrome Coronavirus disease 19 infection, Respiratory distress syndrome IMS-001 alone AgeX Therapeutics Inc, Imstem Biotechnology Inc Phase Not Applicable Planned 0 2020-11-04
Open-label, Multicenter Study to Evaluate the Efficacy of PLX-PAD for the Treatment of COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome PLX stem cell therapy, Pluristem/Cha Bio & Diostech alone, best standard medical care alone IL-6 receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Pluristem Ltd, Pluristem Therapeutics Inc Germany, Israel 2020-11-30 2022-03-31 NCT04614025, PLX-COV-03 Phase 2a Clinical Recruiting 8 16 Months 40 Alona Paz, Dr, Alona Paz, Dr., Asaf Peretz, Dr, Asaf Peretz, Dr., Ayelet Raz-Pasteur, Dr, Ayelet Raz-Pasteur, Dr., Christian Karagiannidis, Prof. Dr, Christian Karagiannidis, Prof. Dr., Christian Putensen, Prof. Dr, Christian Putensen, Prof. Dr., Elias Mazen, Prof, Elias Mazen, Prof., Julia Kovalenko, Dr, Julia Kovalenko, Dr., Ronny Ben-Avi, Dr, Ronny Ben-Avi, Dr. 2020-11-05
REHSCU: Remimazolam Infusion in the Context of Hypnotic Shortage in the Critical Care Unit During the Pandemic of COVID-19 Coronavirus disease 19 infection remimazolam alone GABA A receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) CHU De Nantes PAION UK Ltd France 2020-11-01 2021-05-01 NCT04611425, RC20-0319, REHSCU Phase 2 Clinical Not yet recruiting 1 6 Months 30 Antoine ROQUILLY, MD, PhD, Bertrand ROZEC, MD, PhD, Raphaël CINOTTI, MD 2020-11-05
CoV-PREMOC: Sars-CoV-2 Infection (Covid-19) During Pregnancy: Effects on Mother and Child Coronavirus disease 19 infection biological sampling alone, magnetic resonance imaging alone, ultrasound alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Klinikum Grosshadern Der Ludwig-Maximilians-Universitat Germany 2020-11-06 20-733, CoV-PREMOC, DRKS00023447, LMU-RAD00530 Phase Not Applicable Not yet recruiting 1 30 Sophia Stöcklein, Vanessa Koliogiannis 2020-11-04
Effects of COVID-19 on levels of stress and anxiety in dental students Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Heidelberg Germany 2020-11-03 DRKS00023499, S-627/2020 Phase Not Applicable Recruiting 1 100 Andreas Zenthöfer, Anna-Luisa Klotz 2020-11-04
A prospective, multicentre, observational study to evaluate the feasibility of extracorporeal blood purification (EBP) using the company’s Oxiris filter set in severely ill patients with COVID-19 Coronavirus disease 19 infection Baxter's Prismaflex system alone, Oxiris filter set alone, extracorporeal blood purification alone Baxter International Inc Italy Phase Not Applicable Status not specified 1 37 Gianluca Villa 2020-11-04
Diagnostic Performance of an Antigen Test for SARS-CoV-2 Infection (COVID-19) Coronavirus disease 19 infection Quidel Sofia SARS Antigen Fluorescent Immunoassay alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Carilion Clinic US 2020-11-01 2021-01-31 EPLING-533, IRB-20-1088, NCT04610489 Phase Not Applicable Not yet recruiting 1 3 Months 800 John W Epling, MD 2020-11-05
CONTACT: A Study to Assess Infection Rate of Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2) and It's Affect on Quality of Life in Adult Volunteers in Lake County, Illinois Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) AbbVie Inc US 2020-10-30 2021-09-24 CONTACT, H20-308, NCT04611230 Phase Not Applicable Not yet recruiting 1 10 Months 1250 ABBVIE CALL CENTER, AbbVie Inc. 2020-11-05
SARS-COV2 Pandemic Serosurvey in a Rare Disease Population Coronavirus disease 19 infection, Rare disease Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Allergy and Infectious Diseases National Institutes of Health Clinical Center US 2020-11-09 2023-04-30 000210-I, 10000210, NCT04609085 Phase Not Applicable Recruiting 2 29 Months 5000 Matthew J Memoli, M.D. 2020-11-05
Aerosol Transmission of Severe Acute Respiratory Syndrome Coronavirus of Coronavirus Disease 2019 Coronavirus disease 19 infection Real-time-polymerase-chain reaction alone, cell culture alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Italiano de Buenos Aires Argentina 2020-05-08 2021-01-01 1345, NCT04609774 Phase Not Applicable No longer recruiting 1 7 Months 8 VANINA LAURA PAGOTTO 2020-11-05
Endothelial Damage and Angiogenesis Biomarkers During COVID-19 Coronavirus disease 19 infection, Vascular disease ELISA kit alone, enzyme-linked immunosorbent assay alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Chile Chile 2020-11-30 2021-11-30 NCT04609332, OAIC/20 Phase Not Applicable Not yet recruiting 1 12 Months 40 Carlos Romero, M.D., Catalina Valdes, M.D., Felipe Andrés Maldonado Caniulao, Felipe Maldonado, M.D., M.Sc., Mónica Cáceres, Ph.D., Nicolas Valls, M.D., M.Sc., Oscar Cerda, Ph.D. 2020-11-05
A single-center, retrospective study to assess the effects of hydroxychloroquine on COVID-19 in intensive care unit patients Coronavirus disease 19 infection, Viral pneumonia hydroxychloroquine alone Aix-Marseille Université, Assistance Publique Hopitaux De Marseille Phase Not Applicable Status not specified 0 29 2020-11-06
Lung Diffusing Capacity for Nitric Oxide and Carbon Monoxide Early After Mild-to-severe COVID-19 Coronavirus disease 19 infection, Viral pneumonia European Ancestry IRCCS AOU San Martino – IST Italy 2020-05-14 2020-10-12 NCT04610554, SARS-COV-2_DLNO Phase Not Applicable Completed 1 4 Months 74 Giovanni Barisione, MD 2020-11-05
Mesenchymal Stem Cells in Patients Diagnosed With COVID-19 Coronavirus disease 19 infection, Lung injury, Multiple organ failure, Respiratory insufficiency adipose tissue derived-mesenchymal stem cells alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Instituto De Seguridad Y Servicios Sociales De Los Trabajadores Del Estado Instituto de Terapia Celular: ITC Mexico 2020-08-01 2020-12-30 060I.2020, NCT04611256 Phase 1 Clinical Recruiting 1 4 Months 20 M. Eunice Rodríguez Arellano, Martha E. Rodríguez Arellano, MD 2020-11-06
A clinical trial of NeuCovix-HT for the detection of functional antibodies in plasma or serum that neutralize the SARS-CoV-2 (COVID-19) virus Coronavirus disease 19 infection NeuCovix-HT alone Axim Biotechnologies Inc Phase Not Applicable Planned 0 2020-11-03
Long-term Follow-up in Survivors of Critical Illness Cognitive disorder, Coronavirus disease 19 infection, Psychiatric disorder, Respiratory distress syndrome, Viral pneumonia Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia Universita degli Studi di Brescia Italy 2020-06-01 2021-07-01 NCT04608994, NP2595 Phase Not Applicable Recruiting 1 13 Months 160 Nicola Latronico, Professor, Piva Simone, Simone Piva 2020-11-05
Delivery During COVID-19 Pandemic: Implications for Obstetrics, Maternal Psychopathology, and Mother-Infant Relationship Coronavirus disease 19 infection, Postnatal depression Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Hillel Yaffe Medical Center Israel 2020-06-01 2024-06-30 0082-20-HYMC, NCT04609501 Phase Not Applicable No longer recruiting 1 49 Months 440 Rinat Gabbay-Benziv, MD 2020-11-06
Surfactant Levels in the Lungs of COVID-19 Patients Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia lung fluid sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Zealand University Hospital Denmark 2020-11-01 2022-10-01 NCT04609488, SJ-859X Phase Not Applicable Not yet recruiting 1 23 Months 30 Henning B Nielsen, Henning Bay Nielsen 2020-11-05
Efficacy of Arbidol in treatment of COVID-19 Coronavirus disease 19 infection Variable regimens including Arbidol (Pharmstandard) , N-acetylcysteine , bromhexine , cetirizine , famotidine , fluticasone propionate , naproxen Histamine H1 receptor antagonist, Histamine H2 receptor antagonist Aged Adults (65-79 yrs), Elderly Adults (80 and over) Babol University of Medical Sciences Iran 2020-11-15 IR.MUBABOL.REC.1399.283, IRCT20201024049134N1 Phase 2 Clinical Not yet recruiting 1 100 Mohammad Barary, Mostafa Javanian, Reza Ghadimi 2020-11-05
TeleRea'nCo: Follow-up of patients with COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopitaux Universitaires de Strasbourg France 2020-10-27 2023-04-27 7883, NCT04609839, TELEREA'NCO, TeleRea'nCo Phase Not Applicable Recruiting 1 30 Months 200 Eric DEMONSANT, Laurence KESSLER, Pr 2020-11-05
An observational, comparative study to evaluate the time to achieve negative nucleic acid testing and hospital stays between danoprevir and lopinavir/ritonavir in the treatment COVID-19 Coronavirus disease 19 infection danoprevir alone, lopinavir + ritonavir alone HIV protease inhibitor, Hepatitis C virus NS3 protease inhibitor Nanchang Ninth Hospital China Phase Not Applicable Status not specified 1 33 2020-11-04
Effectiveness of Tissue plasminogen activator (TPA) for treatment of ARDS induced by COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome regular care alone, alteplase plus enoxaparin sodium Low molecular weight heparin, Tissue plasminogen activator stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Tehran University of Medical Sciences Iran 2020-09-22 IR.TUMS.VCR.REC.1399.025, IRCT20200415047080N1 Phase 3 Clinical Recruiting 1 30 Mohhamad Ali Sahraian, Rasoul Aliannejad 2020-11-05
COVID-VIRO: Diagnostic Performance Evaluation of a Novel SARS-CoV-2 (COVID-19) Antigen Detection Test Coronavirus disease 19 infection COVID-VIRO novel antigen-based rapid detection test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Regional D'Orleans France 2020-10-13 2020-11-13 CHRO-2020-18, COVID-VIRO, NCT04609969 Phase Not Applicable Recruiting 1 1 Month 200 Aurélie DESPUJOLS, Elodie POUGOUE TOUKO, Thierry PRAZUCK, Thierry PRAZUCK, Dr, Thierry PRAZUCK, MD 2020-11-05
LidoCovid: Impact of Intravenous Lidocaine on Clinical Outcomes of Patients With ARDS During COVID-19 Pandemic Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia lidocaine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopitaux Universitaires de Strasbourg 2020-11-04 2024-02-04 7820, LidoCovid, NCT04609865 Phase 3 Clinical Not yet recruiting 0 39 Months 100 Thiên-Nga CHAMARAUX-TRAN, MD 2020-11-06
INSPIRE: Innovative Support for Patients With SARS-COV2 Infections (COVID-19) Registry Coronavirus disease 19 infection innovative support digital platform alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rush University Medical Center Jefferson Medical College, University of California Los Angeles, University of California San Francisco, University of Texas Health Science Center Houston, University of Texas Southwestern Medical Center, University of Washington, Yale University US 2020-11-14 2022-11-14 75D30120C08008, INSPIRE, NCT04610515 Phase Not Applicable Not yet recruiting 8 24 Months 4800 Ahamed Idris, MD, Anna Marie Chang, MD, Annie Lee, PhD, Bala Hota, MD, Doug Bell, MD, PhD, Elizabeth Vidales, Grace Amadio, Graham Nichol, MD, Henry Wang, MD, Jacqueline Brown, Joann Elmore, MD, Katherine Koo, Keith Jerome, MD, Kelli O'Loughlin, MD, Lauren Wisk, PhD, Matthew Thompson, MD, Michael Gottlieb, MD, Michelle Santangelo, Nicole Renzi, Nikki Gentile, MD, Paula Arellano-Cruz, Ralph Wang, MD, Raul Moreno, Robert A Weinstein, MD, Robert Rodriguez, MD, Robin Kemball, Victoria Lyon 2020-11-06
Evaluation of the efficacy and safety of Doxycycline in combination with standard treatment in Covid-19 patients Coronavirus disease 19 infection doxycycline alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shahid Sadoughi University of Medical Sciences and Health Services Iran 2020-09-14 IR.SSU.MEDICIN E.REC.1399.140, IRCT20191211045691N2 Phase 3 Clinical No longer recruiting 1 60 Dr.Masoud Mirzaei, Mohammad Bagher Owlia, Seyed Ruhollah Mousavinasab, Zohreh Akhoundi Meybodi 2020-11-05
Evaluation of the effect of ghamz with needle on improvement of respiratory symptoms of COVID-19 patients admitted to hospital Coronavirus disease 19 infection, Respiratory disease conventional medical treatment alone, ghamz massage-acupuncture therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Shiraz University of Medical Sciences Iran 2020-04-13 2020-07-20 IR.SUMS.REC.1399.043, IRCT20150825023753N17 Phase 3 Clinical Completed 1 3 Months 18 Dr. Amir Mohammad Jaladat, Dr. Mohammad Mahdi Parvizi, Dr. Younes Ghasemi 2020-11-05
Immune Defence: Evaluating nasal sprays and physical activity/stress management in reducing respiratory infections in primary care Coronavirus disease 19 infection, Respiratory tract infection Saline nasal spray alone, Vicks First Defence nasal spray alone, physical activity and stress management alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Of Southampton National Institute for Health Research (NIHR) UK 2019-09-01 2024-10-01 56474, IRAS 288431, CPMS 47080, ISRCTN17936080, Immune Defence Phase Not Applicable Recruiting 3 61 Months 15000 Dr Jane Vennik, Mrs Kate Martinson 2020-11-05
Evaluation of the Effectiveness of an Oral Antiseptic in Improving the Clinical Status, Decreasing Viral Load and Its Prolonged Action in Patients with COVID-19 Coronavirus disease 19 infection Tooth brushing alone, gargling / mouthwash a day alone, toothpaste alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Sao Paulo Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Brazil 2020-08-10 34070620.6.0000.5417, 4.212.624, RBR-58ftdj, U1111-1255-3454 Phase Not Applicable Recruiting 1 40 Bernardo da Fonseca Orcina, Paulo Sérgio da Silva Santos 2020-11-06
Aftogel and COVID-19 PCR test Coronavirus disease 19 infection Aftogel strip alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Iran 2020-11-21 IR.MUI.REC.1399.520, IRCT20181208041886N2 Phase 2 Clinical Not yet recruiting 1 60 Dr. Mohsen Saniei, Dr. Morteza Pourahmad 2020-11-03
Study of ZnAg Liquid Solution to Treat COVID-19 Symptomatic Participants Coronavirus disease 19 infection CNM-AgZn-17 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Clene Nanomedicine Inc Azidus Brasil 2020-12-31 2021-08-31 CNMZNAG.202, NCT04610138 Phase 2 Clinical Not yet recruiting 0 8 Months 238 Renata Lourencini, Robert Glanzman, MD 2020-11-05
Redploy: Lessons from the frontline: the impact of redeployment during COVID-19 on nurse wellbeing, performance and retention Coronavirus disease 19 infection Bradford Teaching Hospitals NHS Foundation Trust National Institute for Health Research (NIHR) UK 2020-10-01 2022-03-31 ISRCTN18172749, NIHR132041, Redploy Phase Not Applicable Not yet recruiting 3 18 Months 48 Dr Jenni Murray, Prof Rebecca Lawton 2020-11-03
Effect of Melatonin in treatment of COVID-19 Coronavirus disease 19 infection melatonin alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hamadan University of Medical Sciences Iran 2020-10-22 IR.UMSHA.REC.1399.592, IRCT20200426047206N4 Phase 3 Clinical Recruiting 1 60 Dr Saman Talebi, Saeed Bashirian, Salman Khazaei 2020-11-03
Evaluation of the effect of mucodentol on people with coronavirus Coronavirus disease 19 infection mucodentol (Khorraman Pharmaceutical Company) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Lorestan University Iran 2020-04-25 IR.LUMS.REC.1399.046, IRCT20130428013151N2 Phase 0 Clinical No longer recruiting 1 200 Behrooz Farzan, Ebrahim Fallahi 2020-11-04
Study of the effects of grapefruit extract on COVID-19 Coronavirus disease 19 infection grapefruit seed extract (Nutribiotic Company) plus lopinavir + ritonavir HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Shaheed Beheshti Medical University Iran 2020-04-21 IR.SBMU.RETECH.REC.1399.041, IRCT20140312016968N2 Phase Not Applicable No longer recruiting 1 20 Dr. Afshin Zarghi, Dr. Aliakbar Velayati, Majid Marjani, Seyed Ali Ziai 2020-11-03
A clinical trial of COVID-19-specific T-cells for the treatment of COVID-19 Coronavirus disease 19 infection COVID-19-specific T-cells(Children's National Hospital) alone Children's National Hospital US Phase 1 Clinical Planned 1 2020-11-02
Infrastructure research for understanding the actual situation and pathophysiology of long-term complications of Coronavirus disease 2019 (COVID-19) Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) School of Medicine, Keio University Japanese Ministry of Health, Labor and Welfare Japan 2020-11-02 UMIN000042299 Phase Not Applicable Not yet recruiting 1 2000 Koichi Fukunaga, Makoto Ishii 2020-11-03
VoViThel: SARS-COVID-Endotheliitis Study via Retinal Vascular Analysis (COVID-19) Coronavirus disease 19 infection, Ocular disease flicker-light stimulation alone, intensive care therapy alone, retinal vascular analysis alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Jena University Hospital Germany 2020-09-14 2020-1805BO, DRKS00023334, VoViThel Phase Not Applicable Recruiting 1 30 Richard Biedermann 2020-11-04
Cod Liver Oil for COVID-19 Prevention Study Coronavirus disease 19 infection, Respiratory tract infection Cod liver oil alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Oslo University Hospital Norwegian Institute of Public Health, University of Oslo Norway 2020-11-10 2023-05-31 NCT04609423, REK-172796 Phase 4 Clinical Not yet recruiting 1 30 Months 80000 Arne Søraas, MD, PhD, John Arne Dahl, PhD, Merete Ellingjord-Dale, PhD 2020-11-04
SECR-01: Efficacy and Safety of Two Hyperimmune Equine Anti Sars-CoV-2 in COVID-19 Patients Coronavirus disease 19 infection Variable regimens including Equine Imunoglobulin anti SARS Cov 2 , acetaminophen , chlortrimeton , cimetidine Histamine H2 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Costa Rican social security box Ministry of Health of Costa Rica, Universidad De Costa Rica Costa Rica 2020-09-06 2020-12-06 NCT04610502, R020-SABI-00259, SECR-01 Phase 2 Clinical Recruiting 4 3 Months 26 Alfredo Sanabria, PhD, Ann Echeverri, MD, Douglas Montero, MD, Henry Chan, MD, Ileana Balmaceda, MD, Jorge Jiménez, MD, Jose Pablo Madrigal, MD, José Acuña, MD, Juan Ignacio Silesky, MSc, Mario Sibaja, MD, Rodrigo Aguilar, MD, Taciano Lemos, MD, Willem Bujan, MBA 2020-11-05
Nano-COVID19: Treatment of Patients With Mild Coronavirus-19 (COVID-19) Disease With Methotrexate Associated to LDL Like Nanoparticles Coronavirus disease 19 infection MTX-LDE plus leucovorin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo Hospital Santa Marcelina Brazil 2020-10-27 2021-07-15 36746020.5.1001.0068, NCT04610567, Nano-COVID19 Phase 1/Phase 2 Clinical Recruiting 3 8 Months 100 Jose Salvador Oliveira, MD, PhD, Lucas Marinho, MD, Raul Cavalcante Maranhão, Raul Maranhão, MD, PhD, Rodrigo Esper, MD, PhD 2020-11-05
WIN COVID-19: Low dose lung X-ray therapy for COVID-19 Coronavirus disease 19 infection, Viral pneumonia Antibiotics alone, Low dose radiotherapy alone, statins alone, Variable regimens including Alteplase , Convalescent plasma , Dexamethasone , Enoxiparin , Methylprednisolone , Mycobacterium w , N acetyl cysteine , Oxygen , Paracetamol , Remdesvir , Tocilizumab , Ulinastatin , Vitamin C , Vitamin D , Zinc , pirfenidone , thiamine Interferon gamma receptor agonist, MAPK gene modulator, PDGF receptor antagonist, TGF beta receptor antagonist, TLR-2 agonist, TLR-4 agonist, TLR-9 agonist, p38 MAP kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) HarshaMitra Superspecialty Cancer Centre and Research Institute, Sundaram Hospital India 2020-11-06 CTRI/2020/10/028597, WIN COVID-19 Phase 2 Clinical Not yet recruiting 1 61 Govindaraj Ganesan, Sasipriya P, Vivek Sundaram 2020-11-04
Psychological coping with the COVID-19-pandemic Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder, Psychiatric disorder Google Forms program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Leukämie Lymphom Liga e.V.Universitätsklinikum Düsseldorf Germany 2020-05-12 2020-975, DRKS00021756 Phase Not Applicable Recruiting 1 9000 Jonas Jansen 2020-11-05
Trends of Symptoms in Patients Under Institutional Isolation in COVID-19 Pandemic in India - An Observational study Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Medical Sciences India 2020-10-26 CTRI/2020/10/028639 Phase 4 Clinical Not yet recruiting 1 1000 Dr Balbir Kumar 2020-11-03
To assess the overall effect of COVID-19 on intent of treatment and staging of cancer Cancer, Coronavirus disease 19 infection Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Max Super Speciality Hospital India 2020-11-02 CTRI/2020/10/028648 Phase Not Applicable Not yet recruiting 1 350 Dr Aditi Chaturvedi 2020-11-04
Clinical trial to study the effect of Budesonide taken through inhalation in mild COVID cases Coronavirus disease 19 infection Budesonide alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) sparsh chest diseases center Department of Health and Family Welfare, Government of Gujarat India 2020-10-23 CTRI/2020/10/028581 Phase 3 Clinical Not yet recruiting 4 1000 Dr Anand Patel, Dr Jayeshkumar Dobariya, Dr Jigna Dave, Dr Parul Vadgama, Dr Tushar Patel 2020-11-05
Effectiveness of an online training module with lectures and videos regarding maternal and newborn care during COVID 19 pandemic on the knowledge and acceptability among nursing students Coronavirus disease 19 infection E - learning module alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) AIIMS Rishikesh India 2020-10-26 CTRI/2020/10/028580 Phase Not Applicable Not yet recruiting 1 50 Levis Murry, cecilia mary 2020-11-04
Long-term Evolution of Pulmonary Involvement of Novel SARS-COV-2 Infection (COVID-19): Follow the COVID Study Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Policlinico S.Orsola-Malpighi Italy 2020-07-30 2021-07-30 714/2020/OSS/AOUBO, NCT04605757 Phase Not Applicable Recruiting 1 12 Months 100 Dr. Stefano Nava, Irene Prediletto, MD-PhD, Irene Prediletto, MD-Phd, Stefano Nava, MD, Stefano Nava, MD, FERS 2020-11-02
Evaluate the Safety, Immunogenicity and Potential Efficacy of an rVSV-SARS-CoV-2-S Vaccine Coronavirus disease 19 infection VSV vector-based vaccine targeting spike glycoprotein (COVID-19), IIBR/Weizmann Institute of Science alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Israel Institute for Biological Research Ministry of Health, Israel Israel 2020-10-28 2022-06-01 IIBR 20-001, NCT04608305 Phase 1/Phase 2 Clinical Recruiting 2 19 Months 1040 Eytan Ben Ami, Dr., Hadar Marcus, Dr., Noa Madar Balakirski, Dr., Yoseph Caraco, Prof. 2020-11-04
NICOVID: Evaluation of the Efficacy of Nicotine Patches in SARS-CoV2 (COVID-19) Infection in Hospitalized Patients Coronavirus disease 19 infection nicotine transdermal patch alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-11-30 2022-06-30 2020-003743-28, APHP200529, NCT04608201, NICOVID Phase 3 Clinical Not yet recruiting 1 19 Months 220 Valérie POURCHER, MD, PhD, Zahir AMOURA, MD, PhD, Zahir AMOURA, MD,PhD 2020-11-04
Treat COVID-19 Patients With Regadenoson Coronavirus disease 19 infection, Lower respiratory tract infection, Lung inflammation, Lung injury regadenoson alone Adenosine A2a receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Maryland Baltimore County US 2020-11-01 2022-01-31 HP-00091372, NCT04606069 Phase 1/Phase 2 Clinical Not yet recruiting 1 15 Months 40 Christine L Lau, MD, MBA, Manal Al-Suqi, MSTC, Melissa Culligan, RN 2020-11-05
ComCor: Study of Socio-demographic Factors, Behaviors and Practices Associated With Infection With SARS-CoV-2 Responsible for COVID-19 Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institut Pasteur Ipsos France 2020-10-27 2021-06-30 2020-047, 2020-A02560-39, ComCor, NCT04607941 Phase Not Applicable Recruiting 3 8 Months 57720 Arnaud Fontanet, Pr, Carole Blanc, Christophe David, Faiza Omar, Nathalie Jolly, Tiffany Charmet, DVM, MPH 2020-11-03
Inhaled NO for the Treatment of Viral Pneumonia in Adults Coronavirus disease 19 infection, Viral pneumonia LungFit alone, nitric oxide alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Beyond Air Inc 2020-11-07 2021-09-07 BA_VPLF_01, NCT04606407 Phase 2 Clinical Not yet recruiting 0 10 Months 90 Asher Tal, Meital Hatan, Rinat Kalaora 2020-11-04
PURIFY-OBS-1: PURIFY-OBS: Blood Purification With Seraph 100 Microbind Affinity Blood Filter for Treatment of Severe COVID19 Observational Study Acute lung injury, Adult respiratory distress syndrome, Coronavirus disease 19 infection, Respiratory failure Seraph 100 Microbind alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Henry M Jackson Foundation for the Advancement of Military Medicine Uniformed Services University of the Health Sciences US 2020-11-20 2022-02-01 NCT04606498, PURIFY-OBS-1, PURIFY-OBS-1 Phase Not Applicable Not yet recruiting 1 14 Months 200 Ian Stewart, MD, Kevin Chung, MD, Marianne Spevak, BSHS, Sophie Haralson, Stephen Olsen, MD 2020-11-06
AirS: SARS-CoV-2 in Air (COVID-19) Coronavirus disease 19 infection air sampler alone, breath sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Bonn Germany 2020-11-16 398/20, AirS, DRKS00023435 Phase Not Applicable Not yet recruiting 1 15 Ricarda Schmithausen 2020-11-03
ELISA: Lubecker longitudinal study on Infections with SARS-CoV-2 (COVID-19) Coronavirus disease 19 infection SARS CoV-2 sequencing alone, brief smell identification test alone, enzyme-linked immunosorbent assay alone, metabolite test alone, peripheral blood mononuclear cell analysis alone, polymerase chain reaction test alone, serum antibody test alone, urine analysis alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitatsklinikum Schleswig-Holstein Campus Lubeck, University of Lubeck Deutsche Forschungsgemeinschaft (DFG), German Federal Ministry of Education and Research Germany 2020-05-06 20-150, DRKS00023418, ELISA Phase Not Applicable Recruiting 1 3000 Alexander Katalinic, Christine Klein 2020-11-03
A study to assess safety and efficacy of emricasan for the potential treatment of mild-COVID-19 Coronavirus disease 19 infection emricasan (iv, liver transplantation/portal hypertension), Conatus alone Caspase inhibitor Amerimmune Llc US Phase Not Applicable Planned 1 2020-10-30
LAPCOV: Laparoscopy and COVID-19 Contamination Coronavirus disease 19 infection laparoscopy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-11-01 2022-01-01 APHP200611, LAPCOV, NCT04608383 Phase Not Applicable Not yet recruiting 1 14 Months 20 Laura RUSCIO, Laura RUSCIO, MD, PhD 2020-11-04
MBI: Evaluation of Occupational Burnout and Stress Among Dentists in Covid-19 Pandemic Acute stress disorder, Coronavirus disease 19 infection Akdeniz University Turkey 2020-03-09 2020-05-20 KAEK- 590, MBI, NCT04605692 Phase Not Applicable Completed 1 2 Months 706 Merve Özarslan 2020-11-03
CoRe (ADHOK): SARS-CoV-2 (COVID-19) registry for oncological and hematological patients in Germany Aplastic anemia, Cancer, Coronavirus disease 19 infection, Immune thrombocytopenic purpura, Myelodysplastic syndrome, Myeloproliferative disorder, Paroxysmal nocturnal hemoglobinuria St. Marien-Krankenhaus Siegen gem. GmbH Klinikum Bayreuth Klinik und Institut für Nuklearmedizin Germany 2020-06-01 CoRe (ADHOK), DRKS00023012 Phase Not Applicable Recruiting 26 170 Alexander Kiani, Romina Rösch 2020-11-03
Orthopedic Surgery in The Pandemic Era Coronavirus disease 19 infection SARS CoV-2 immunoglobulin G and IgM antibody test alone University of Indonesia Indonesia 2020-04-01 UMIN000042052 Phase Not Applicable Completed 1 35 Achmad Kamal, I Wayan Arya Mahendra Karda 2020-11-02
FIBRO-COVID: Pirfenidone compared to placebo in post-Covid19 pulmonary fibrosis Coronavirus disease 19 infection, Pulmonary fibrosis, Respiratory distress syndrome, Viral pneumonia Corticosteroid treatment alone, pirfenidone alone PDGF receptor antagonist, TGF beta receptor antagonist, p38 MAP kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institut Investigació Biomèdica Bellvitge Spain 2020-08-01 2021-08-01 2020-002518-42, FIBRO-COVID, NCT04607928 Phase 2 Clinical Recruiting 8 12 Months 148 Claudia Valenzuela, PI, David Jimenez, MD, PhD, Diego Castillo, PI, Eva Balcells, PI, Guadalupe Bermudo, MD, PhD, Guadalupe Bermudo, PI, Jacobo Sellarés, PI, Juan Rigual, PI, Karina Portillo, PI, Maria Molina, Maria Molina-Molina, MD, PhD, Piedad Usetti, MD, PhD, Rosalia Laporta, PI 2020-11-04
A retrospective, case series to evaluate the outcomes and biomarkers analyses among patients with COVID-19 treated with sarilumab in Italy Coronavirus disease 19 infection sarilumab alone IL-6 receptor antagonist Fondazione G Pascale Italy Phase Not Applicable Status not specified 1 15 2020-10-30
CVP-Covid19: Cardiovascular Disease Progression and Prognosis in COVID-19 Cardiovascular disease, Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universita di Bologna Italy 2020-09-20 2021-12-31 CVP-Covid19, CV_SPP_COVID19, NCT04606732 Phase Not Applicable Recruiting 1 15 Months 2000 Maria Carla Re, Olivia Manfrini, Olivia Manfrini, MD 2020-11-04
PICN: Psychological Impact of Covid-19 Among Nurses in Hospital Sultanah Nora Ismail, Batu Pahat Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression HOSPITAL SULTANAH NORA ISMAIL, BATU PAHAT Malaysia 2020-11-01 2021-03-31 NMRR-20-2291-55972, PICN, PICN 1.0, Version 1. 55972 Phase Not Applicable Not yet recruiting 1 5 Months 787 NURUL ASYHIKIN BINTI MOHD FADZIL 2020-11-05
ARBs CORONA II: Host Response Mediators in Coronavirus (COVID-19) Infection: Is There a Protective Effect of Losartan on Outcomes of Coronavirus Infection? Coronavirus disease 19 infection, Multiple organ failure losartan alone Angiotensin II AT-1 receptor antagonist, Angiotensin II receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of British Columbia Canadian Institutes of Health Research Spain, Belgium, US, Canada, France, Japan 2020-10-09 2021-06-30 ARBs CORONA II, H20-01984, NCT04606563 Phase 3 Clinical Recruiting 19 8 Months 1372 Andre Kalil, MD, Anish Mitra, MD, Antonio Torres, MD, Brent Winston, MD, David Maslove, MD, David Sweet, MD, Francois Lamontagne, MD, Gregory Haljan, MD, J. Matthew Luther, MD, James A Russell, MD, John Boyd, MD, John Marshall, MD, Karen Tran, MD, Keith Walley, MD, Lynda Lazosky, Matthew Cheng, MD, Mitchell Levy, MD, Omar Sharif, MD, Peter Birks, MD, Pierre Asfar, MD, Puneet Mann, Puneet Mann, MSc, Rahim Kachra, MD, Robert Fowler, MD, Santiago Perez, MD, Steve Reynolds, MD, Taka-aki Nakada, MD, Thierry Dugernier, MD, Vicente Corrales-Medina, MD, Xavier Wittebol, MD 2020-11-03
VOCOVID: An open-label, single-center, investigator-initiated, exploratory trial to evaluate the safety and the antiviral effects of voclosporin versus tacrolimus in kidney transplant recipients (KTRs) with COVID-19 (SARS-CoV-2) Coronavirus disease 19 infection, Kidney transplantation voclosporin alone Calcineurin inhibitor, IL-2 receptor antagonist Aurinia Pharmaceuticals Inc Netherlands 2020-10-27 VOCOVID Phase Not Applicable Recruiting 1 20 Dr Aiko P.J. de Vries, Dr Y.K. Onno Teng 2020-10-30
Study to Find the Percentage of Cases Retaining COVID-19 IgG Antibodies 45 to 65 After They Have Tested Positive Coronavirus disease 19 infection ErbaLisa COVID-19 kit (Erba Corporate Services) alone, enzyme-linked immunosorbent assay alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Tata Main Hospital India 2020-07-01 2020-08-30 152473, NCT04605952 Phase Not Applicable Completed 1 1 Month 201 Dr.Deb Sanjay Nag 2020-11-03
Study of Nebulized Ampion for the Treatment of Adult COVID-19 Patients With Respiratory Distress Coronavirus disease 19 infection, Respiratory distress syndrome Ampion (intranasal, inflammation), Ampio/DMI Biosciences alone, standard of care alone Stem cell antigen-1 inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ampio Pharmaceuticals Inc US 2020-10-27 2021-03-31 AP-014, NCT04606784 Phase 1 Clinical Recruiting 1 5 Months 40 Ampio Pharmaceuticals, Inc, Ampio Pharmaceuticals, Inc. 2020-11-02
EQUINOX: A Study to Evaluate the Efficacy and Safety of Itolizumab in Subjects Hospitalized With COVID-19 Coronavirus disease 19 infection, Viral pneumonia itolizumab alone T-cell differentiation antigen CD6 inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Equillium Inc Biocon Ltd US 2020-11-30 2021-06-30 EQ001-20-001, EQUINOX, NCT04605926 Phase 3 Clinical Not yet recruiting 1 7 Months 800 Ivor S. Douglas, M.D, Maple Fung, MD, Stephanie Leyva 2020-11-04
WEAICOR: Wearables to Investigate the Long Term Cardiovascular and Behavioral Impacts of COVID-19 Cardiovascular disease, Coronavirus disease 19 infection Biostrap wristband device alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tulane University US 2020-06-09 2022-06-30 2020-678, NCT04605965, WEAICOR Phase Not Applicable Recruiting 2 24 Months 100 Agnieska Drutel, PhD, Agnieszka Drutel, PhD, Agniezska Drutel, PhD, Arezu Bhatnagar, MD, MSCRM, Monique Rhodes, JD, Nassir Marrouche, MD 2020-11-04
AR0-CROWN: Effect of tenofovir / emtricitabine short course on viral clearance in outpatient SARS-CoV2 (COVID-19) infected patients Coronavirus disease 19 infection tenofovir disoproxil fumarate + emtricitabine (fixed dose), Gilead Sciences alone HIV-1 reverse transcriptase inhibitor, Nucleoside reverse transcriptase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) CHU de Caen France 2020-10-15 20-070, 2020-001867-94, AR0-CROWN Phase 3 Clinical Recruiting 1 180 Coordinator Investigator 2020-11-02
CYCLOVID: Evaluation of Alisporivir for the Treatment of Hospitalised Patients With Infections Due to SARS-CoV-2 (COVID-19) Coronavirus disease 19 infection alisporivir alone, standard of care alone Cytochrome P450 3A4 inhibitor, Peptidyl-prolyl cis-trans isomerase A inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris Debiopharm SA France 2020-11-01 2021-08-04 2020-002295-13, APHP200552, CYCLOVID, NCT04608214 Phase 2 Clinical Not yet recruiting 2 9 Months 100 Jean-Michel PAWLOTSKY, MD, PhD, Raphaël LEPEULE, MD 2020-11-04
NoCo-CoBio: Northern Colorado COVID-19 Biobank Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Colorado State University University of Colorado Health US 2020-07-08 2022-07-30 20-10063H, NCT04603677, NoCo-CoBio Phase Not Applicable Recruiting 4 24 Months 200 Bridget Baxter, Elizabeth P Ryan 2020-11-03
PSY HCW Kel: The Psychological Impacts of Covid-19 Pandemic and Its Associated Socio-demographic Characteristics Among Government Health Care Workers in Kelantan, Malaysia Coronavirus disease 19 infection, Psychiatric disorder Healthy volunteers accepted Jabatan Kesihatan Negeri Kelantan Malaysia 2020-11-01 2021-02-01 56611, NMRR-20-2306-56611, PSY HCW Kel Phase Not Applicable Status not specified 1 3 Months Dr Noor Hashimah binti abdullah, Dr Tiong Wen Ning 2020-10-30
Morbidity Post COVID-19 - Investigation and call to action Coronavirus disease 19 infection Spirometry alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Griffith University, Royal Brisbane & Women's Hospital Royal Brisbane & Womens Hospital Research Foundation Australia 2020-11-02 2021-07-30 ACTRN12620001114932p Phase Not Applicable Not yet recruiting 2 8 Months 200 Dr Jennifer Paratz 2020-11-06
SOBI: Anakinra, COVID-19, Cytokine Storm Coronavirus disease 19 infection, Respiratory failure, Systemic inflammatory response syndrome, Viral pneumonia anakinra alone Type I IL-1 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Weill Medical College of Cornell University Swedish Orphan Biovitrum AB US 2020-11-30 2022-02-28 20-07022396, NCT04603742, SOBI Phase 2 Clinical Not yet recruiting 1 15 Months 100 Iris Y Navarro-Millan, MD, MSPH 2020-11-04
Best larnyngoscopes for tracheal intubation in covid patient with intubation box Coronavirus disease 19 infection CMAC video laryngoscope alone Young Adults (18-44 yrs) All India Institute of Medical Sciences India 2020-11-04 CTRI/2020/10/028637 Phase 3 Clinical Not yet recruiting 1 100 Dr Balbir Kumar 2020-10-29
Covid-19 infection during pregnancy and its effect on the mother and baby Coronavirus disease 19 infection Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Christian Medical College and Hospital India 2020-11-01 CTRI/2020/10/028636 Phase Not Applicable Not yet recruiting 1 100 Kavita Mandrelle 2020-10-30
Efficacy of Mouthwash in Reducing Salivary Carriage of COVID-19 Coronavirus disease 19 infection Betadine mouthwash alone, Peridex alone, RT-PCR alone, hydrogen peroxide alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ohio State University US 2020-10-01 2020-11-30 2020H0346, NCT04603794 Phase 4 Clinical Recruiting 1 2 Months 60 David Hall, Associate Professor, David L Hall, DDS, Purnima Kumar, PhD,DDS 2020-10-30
Use of Virunil an ayurvedic medicie as a supportive treatment in management of COVID-19 Coronavirus disease 19 infection Virunil alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) NRI Medical College India 2020-11-02 CTRI/2020/10/028635 Phase 2/Phase 3 Clinical Not yet recruiting 1 150 Dr K V S Kumar Chowdary, Dr Kuricheti S S Siva Krishna, Dr V Siva Prabodh 2020-10-29
Evaluation of Self-Collected Saliva Samples Without Viral Transport Media for SARS-CoV-2 Testing Via RT-PCR Coronavirus disease 19 infection BioFire system alone, Cepheid system alone, Eppendorf Thermal Cycler PCR system alone, FilmArray system alone, GeneXpert system alone, Torch system alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) David Grant USAF Medical Center US 2020-10-31 2021-02-28 FWH20200198H, NCT04604145 Phase Not Applicable Not yet recruiting 1 4 Months 600 Antoinette McNeary-Garvin, MSN, Benjamin D Ramos, MD, Benjamin Ramos, Maj 2020-11-04
Comparison of Efficacy of Dexamethasone and Methylprednisolone in Moderate-to-Severe COVID-19 Disease Coronavirus disease 19 infection Decadron alone, methylprednisolone (Pfizer) alone, Variable regimens including Decadron , convalescent plasma , methylprednisolone (Pfizer) , oxygen , tocilizumab Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Fatima Memorial Hospital Pakistan 2020-05-30 2020-07-01 FMH-06-2020-IRB-763-M, NCT04603729 Phase 3 Clinical Completed 1 1 Month 100 Arzinda F Syeda, MBBS, FCPS, Khurshid A Khan, MBBS, FACM 2020-10-30
Impact of high flow oxygen therapy on outcomes of COVID-19 patients Coronavirus disease 19 infection, Hypoxia, Respiratory failure high flow nasal oxygen therapy alone, oxygen alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rajendra Institute of Medical Sciences India 2020-11-02 CTRI/2020/10/028634 Phase Not Applicable Not yet recruiting 1 100 Dr Mohd Saif Khan 2020-10-30
Long-COVID19: Pilot Study Into LDN and NAD+ for Treatment of Patients With Post-COVID-19 Syndrome Coronavirus disease 19 infection IontoPatch alone, naltrexone plus nicotinamide adenine dinucleotide (NAD+) Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) AgelessRx US 2020-11-30 2021-06-30 ALRX004, Long-COVID19, NCT04604704 Phase 2 Clinical Not yet recruiting 1 7 Months 60 Sajad Zalzala, MD 2020-10-30
CONFINeo: Lockdown Impact on Spontaneous Premature Birth in a Level III NICU Coronavirus disease 19 infection, Premature labor Newborn Infants (up to 5 months) Central Hospital, Nancy, France France 2020-11-30 2021-05-31 2020PI168, CONFINeo, NCT04605172 Phase Not Applicable Not yet recruiting 1 6 Months 1000 Jean Michel Hascoet, Jean-Michel HASCOET 2020-10-31
Pilot Study Into the Use of Metformin and LDN for Patients With COVID-19 Coronavirus disease 19 infection metformin hydrochloride plus naltrexone AMP activated protein kinase stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) AgelessRx US 2020-11-30 2021-05-31 ALRX003, NCT04604678 Phase 2 Clinical Not yet recruiting 1 6 Months 80 Sajad Zalzala, MD 2020-10-30
Post-COVID-19 Epidemic Depression Assessment in Adults in South Punjab Pakistan Coronavirus disease 19 infection, Depression Islamia University of Bahawalpur Pakistan 2020-11-01 2020-11-15 NCT04604080, U1111-1260-1614 Phase Not Applicable Recruiting 1 384 Anam Sharmeen, MA, Jafir Shirazi, PhD 2020-11-06
ICUcovid: Perceived Stress Among ICU Medical Staff During COVID-19 Crisis Acute stress disorder, Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Liege Belgium 2019-06-26 2020-09-01 ICUcovid, NCT04604769, STRESSICUCOVID Phase Not Applicable Completed 1 14 Months 60 Anne-Sophie Nyssen, Audrey Vanhaudenhuyse 2020-10-31
TriACT: A Triple Combination Antiviral Coronavirus Therapy (TriACT) for COVID-19 Coronavirus disease 19 infection Variable regimens including hydroxychloroquine , nitazoxanide , ribavirin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rutgers University SYNAVIR US 2020-10-31 2021-04-30 NCT04605588, PRO2020001862, TriACT Phase 2 Clinical Not yet recruiting 1 6 Months 70 Helaine Noveck, MPH, Jeffrey L Carson, MD 2020-11-05
Angiotensin 1-7 in the Therapy of Covid19 Coronavirus disease 19 infection, Viral pneumonia angiotensin 1-7 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rambam Health Care Campus Israel 2020-11-30 2024-04-30 0328-20-RMB, NCT04605887 Phase 2 Clinical Not yet recruiting 1 41 Months 120 Anat Ben Meir, BA, Etty Kruzel, DR, Etty Kruzel, Dr. 2020-11-02
CBD Oil for Reducing Emotional Impact of COVID-19 Acute stress disorder, Alcoholism, Anxiety disorder, Coronavirus disease 19 infection, Depression, Drug dependence, Sleep disorder CBD oil alone, hemp plant-derived cannabinoid intake alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Texas Austin Way West Hemp Inc US 2020-12-31 2021-12-31 2020-07-0138, NCT04603781 Phase 2/Phase 3 Clinical Not yet recruiting 1 12 Months 120 Cate Fischer, B.A., Cate Fischer, BA, Michael J Telch, Ph.D. 2020-11-06
Study of Niclosamide in Moderate Hospitalized Coronavirus-19 (COVID-19) Patients Coronavirus disease 19 infection, Lower respiratory tract infection repurposed niclosamide (oral/capsule, COVID-19), ANA Therapeutics alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) ANA Therapeutics US 2020-10-07 2022-06-30 ANA001-001, NCT04603924 Phase 2/Phase 3 Clinical Recruiting 4 20 Months 436 Akash Bakshi, Andrew Bartynski, Andrew Bartyski, Doug Rank, MD 2020-11-05
Inspiratory Muscle Training in Patients With COVID-19 Coronavirus disease 19 infection aerobic exercise with cycle ergometer alone, breathing exercise alone, inspiratory muscle training alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sociedade Beneficente Israelita Brasileira Hospital Albert Einsten Brazil 2020-06-01 2020-10-23 34931220.1.0000.0071, COVID19_IMPACT, NCT04603963 Phase Not Applicable Terminated 1 4 Months 55 Elaine Cristina Pereira 2020-10-31
BEMICOP: Comparison of Two Different Doses of Bemiparin in COVID-19 Coronavirus disease 19 infection, Viral pneumonia bemiparin alone Factor Xa antagonist, Heparin agonist, Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Clinica Universidad de Navarra, University of Navarra Spain 2020-10-26 2021-07-31 BEMICOP, BEMICOP, NCT04604327 Phase 3 Clinical Recruiting 12 9 Months 164 David Filella, Elena Pina, Ernesto Botella, Jessica Abadía, Jorge Cuesta, Miguel Marcos, Ramon Lecumberri, MD, PhD, Ramon Lecumberri, Md, PhD, Ramón Lecumberri, MD, PhD, Rosa Vidal, Sonia Jiménez, Tania Galicia, Vanesa Sendín, Víctor Jiménez Yuste 2020-10-31
ACTION ON COVID-19: A Study to Test Whether BI-764198 Helps Lung Health of People Hospitalized With COVID-19 Adult respiratory distress syndrome, Coronavirus disease 19 infection BI-764198 alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Boehringer Ingelheim International GmbH 2020-10-28 2021-05-05 1434-0009, 2020-003211-96, ACTION ON COVID-19, NCT04604184 Phase 2 Clinical Recruiting 0 6 Months 90 Boehringer Ingelheim 2020-11-04
SAFE PAC Survey: online survey among anaesthesiologists about method of assessing breathing tube before administering anaesthesia duirng Covid 19 pandemic Coronavirus disease 19 infection practice of airway examination survey alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Malankara Orthodox Syrian Church Medical College, Kolenchery India 2020-10-29 CTRI/2020/10/028696, SAFE PAC Survey Phase Not Applicable Not yet recruiting 1 392 DrGirijananadan D Menon 2020-10-29
Can Vitamin C reduces COVID-19 symptoms Coronavirus disease 19 infection vitamin C alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Cancer Institute, Jhajjar, AIIMS India 2020-11-05 CTRI/2020/10/028695 Phase 4 Clinical Not yet recruiting 1 100 DR BALBIR KUMAR 2020-10-29
Expanded Access Program to Provide Bamlanivimab (LY-3819253) for the Treatment of COVID-19 Coronavirus disease 19 infection bamlanivimab alone COVID19 Spike glycoprotein modulator Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Eli Lilly & Co AbCellera Biologics Inc 18165, J2X-MC-Y001, NCT04603651 Phase Not Applicable Recruiting 0 Contact Lilly at 1-800-LillyRx (1-800-545-5979) 2020-11-04
A survey to know effect of Corona pandemic on medical postgraduate student’s mental stress and their attitude to choose anesthesiology as a career Acute stress disorder, Coronavirus disease 19 infection, Psychiatric disorder Survey alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute Of Medical Sciences, Rishikesh India 2020-11-30 CTRI/2020/10/028672 Phase Not Applicable Not yet recruiting 1 500 Ashutosh Kaushal 2020-10-29
Role of NGAL and Cystatin C in Prediction of Acute Kidney Injury Covid-19 Infection Coronavirus disease 19 infection, Renal injury, Respiratory distress syndrome, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ain Shams University Egypt 2020-10-30 2021-03-31 FMASU P82B/2020, NCT04603664 Phase Not Applicable Recruiting 2 5 Months 88 Sanaa Farag Mahmoud Wasfy, Wael S Abdelmegied, professor, eman wasfy, lecturer, sanaa fFM wasfy, MD, sanaa wasfy, lecturer, wael SO osman, MD 2020-11-04
Remdesivir effect in the treatment of corona Coronavirus disease 19 infection remdesivir alone COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Government Medical College, Bhavnagar India 2020-10-30 CTRI/2020/10/028657 Phase Not Applicable Not yet recruiting 1 275 Dr Mitul Upadhyay 2020-11-02
A study to evaluate Easy Check COVID-19 IgM/IgG POC Antibody Test Coronavirus disease 19 infection Easy Check COVID-19 IgM/IgG POC Antibody Test alone Truvian Sciences Inc US Phase Not Applicable Status not specified 1 2020-10-29
Surgery complications rates in pre and post COVID era Coronavirus disease 19 infection general anesthesia alone, regional anesthesia alone Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Homi Bhabha Cancer Hospital India 2020-10-31 CTRI/2020/10/028649 Phase Not Applicable Not yet recruiting 1 888 Deep Kumar Jain 2020-11-02
Study to Investigate the Benefits of Colchicine in Patients With COVID-19 Coronavirus disease 19 infection colchicine alone, standard care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Liaquat University of Medical & Health Sciences Universidad De Murcia Pakistan 2020-11-15 2021-06-14 LUMHS/REC/893, NCT04603690 Phase 3 Clinical Not yet recruiting 1 7 Months 102 Prof. Dr. Ikram Din Ujjan, MBBS, PhD, Prof. Dr. Saeed Khan, PhD 2020-10-30
PIOQ8: Effect of Pioglitazone on T2DM Patients With COVID-19 Coronavirus disease 19 infection, Non-insulin dependent diabetes anti-inflammatory therapy alone, antiviral therapy alone, pioglitazone alone, insulin glargine plus preprandial insulin Insulin ligand, Insulin receptor agonist, Insulin sensitizer, PPAR gamma agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dasman Diabetes Institute Ministry of Health in Kuwait, Texas Diabetes Institute, University of Kuwait US, Kuwait 2020-11-15 2021-06-29 NCT04604223, PIOQ8, RA HM-2020- 011 Phase 4 Clinical Not yet recruiting 3 7 Months 1506 Fahd Al-Mulla, PhD, Mohamed Abu-farha, Mohamed Abu-farha, PhD, Muhammed Abdul-Ghani, MD/PhD, Thamer Alessa, MD 2020-10-30
RINCOVID: Prevalence of COVID-19 in High Altitude: Insights From the Highest City of the World Coronavirus disease 19 infection COVID-PRESTO IgM/IgG test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre d’Expertise sur l’Altitude EXALT Peru 2020-10-26 2020-11-01 NCT04604249, RINCOVID, RINCOVID Phase Not Applicable Recruiting 1 200 Benoit Champigneulle, MD, Ivan Hancco, MD, Samuel Verges, PhD, Samuel Vergès, PhD 2020-10-30
COVIDEIT: Electrical Impedance Tomography: Collapse in Dependent Areas as a Predictor of Response to Prone Position Ventilation in COVID-19 Acute Respiratory Distress Syndrome Coronavirus disease 19 infection, Respiratory distress syndrome electrical impedance tomography alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre de Recherches du Service de Sante des Armees (CRSSA) France 2020-10-31 2022-04-30 2020-COVID19-16, COVIDEIT, NCT04603755 Phase Not Applicable Not yet recruiting 1 18 Months 15 Michael CARDINALE, MD 2020-10-30
The Phase 1b, randomized, double-blind, placebo-controlled study designed to assess the safety, tolerability, and pharmacokinetic/pharmacodynamic profile of BEMPEG in adult patients with mild COVID-19 Coronavirus disease 19 infection bempegaldesleukin alone CD122 agonist, IL-2 receptor agonist Nektar Therapeutics US Phase 1b Clinical Not yet recruiting 1 2020-10-29
Anxiety and Burnout in Anesthetists and Intensive Care Unit Nurses During COVID-19 Pandemic Anxiety disorder, Coronavirus disease 19 infection, Psychotic disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sisli Etfal Hospital Turkey 2020-05-01 2020-06-01 1577, NCT04604119 Phase Not Applicable Completed 1 1 Month 104 Sultan Acar Sevinç 2020-10-31
To Evaluate the Safety and Efficacy of CT-P59 in Patients With Mild to Moderate Syptoms of Severe Acute Respiratory Syndrome COVID-19 Coronavirus disease 19 infection CT-P59 alone COVID19 Spike glycoprotein inhibitor, Moesin modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Celltrion Healthcare Co Ltd South Korea 2020-09-25 2021-09-30 CT-P59 3.2, NCT04602000 Phase 2/Phase 3 Clinical Recruiting 1 12 Months 1020 ChangWoo Park, JiWoong Lim, Yeon-Sook Kim, MD, PhD 2020-10-30
COVID-19 in People With Primary Ciliary Dyskinesia Coronavirus disease 19 infection, Kartagener syndrome University of Bern EUROPEAN LUNG FOUNDATION, PCD Australia, PCD Family Support Group, The Primary Ciliary Dyskinesia Foundation (PCDF), University Of Southampton Switzerland 2020-05-31 2025-05-31 COVID-PCD, NCT04602481 Phase Not Applicable Recruiting 2 60 Months 1000 Claudia E Kuehni, Prof., Eva SL Pedersen, Dr. 2020-11-03
ITHACA: Clinical trial of the investigational drug AMY-101 for the treatment of patients with severe COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome AMY-101 alone Complement C3 inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Amyndas Pharmaceuticals Greece 2020-10-23 2020-004408-32, AMY-101_ITHACA, ITHACA Phase 2 Clinical Recruiting 1 62 Panagiotis Skendros, MD, PhD 2020-10-29
CAMOVID: A Multicenter, Randomized Trial to Evaluate the Efficacy and Safety of Camostat Mesylate for the Treatment of SARS-CoV-2 Infection - COVID-19 in Ambulatory Adult Patients Coronavirus disease 19 infection camostat mesylate alone Serine protease inhibitor, Transmembrane serine protease 2 inhibitor, Trypsin inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-11-30 2022-03-31 2020-003366-39, APHP200702, CAMOVID, NCT04608266 Phase 3 Clinical Not yet recruiting 6 16 Months 596 David Boutboul, MD PhD, Dorothée Vallois, MD, Gaëtan Plantefève, MD, Mariela Skendi, MD, Medhi Khellaf, MD PhD 2020-10-31
Preserving Compassionate End of Life Care in the Pandemic Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) McMaster University Canadian Institutes of Health Research Canada 2020-03-16 2021-06-01 3WPC19, NCT04602520 Phase Not Applicable Recruiting 1 14 Months 135 Deborah Cook, Deborah Cook, MD MSc, Deborah J Cook, MD, France Clarke, RRT 2020-11-03
Ivermectin in Adults With Severe COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia ivermectin alone, standard management alone Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) CES University Colombia 2020-10-31 2021-02-28 ECA-COVID-CES, NCT04602507 Phase 2 Clinical Not yet recruiting 1 4 Months 100 Federico Rodriguez-Vega, MD, Internist, Federico Rodríguez-Vega, MD, Francisco L Ochoa-Jaramillo, MD, MSc, Nora Cardona.-Castro, MD, MSc, PhD, Veronica Posada-Velez, MD, Internist 2020-10-30
COVID-19EXO2: Safety and Efficiency of Method of Exosome Inhalation in COVID-19 Associated Pneumonia Coronavirus disease 19 infection, Viral pneumonia Mesenchymal Stem Cells Exosomes alone, standard therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Clinical Center of Cellular Technologies Samara Regional Clinical Hospital, Siberian State Medical University Russian Federation 2020-10-01 2021-12-30 COVID-19 EXO EXTENDED, COVID-19EXO2, NCT04602442 Phase 2 Clinical Recruiting 1 14 Months 90 Olga Tyumina 2020-10-30
A case report to assess real-world effectiveness data of a patient with sickle cell disease (SCD) treated with voxelotor in the setting of COVID‐19 Coronavirus disease 19 infection, Sickle cell anemia voxelotor alone Hemoglobin alpha subunit modulator Global Blood Therapeutics Inc Phase 4 Clinical Status not specified 0 2020-10-28
A phase III trial to evaluate MT-2766 in the treatment of subjects with COVID-19 Coronavirus disease 19 infection MT-2766 alone TLR-9 agonist Medicago Inc 2020-12-31 Phase 3 Clinical Planned 0 2020-10-29
The Evaluation of Nitric Oxide Generating Lozenges on Outcome in Newly Diagnosed COVID-19 Patient of African Americans Coronavirus disease 19 infection NOviricid alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), African Ancestry Nitric Oxide Innovations LLC US 2020-10-28 2021-07-31 IND150758 PILOT, NCT04601077 Phase 2/Phase 3 Clinical Recruiting 4 9 Months 100 John C Somberg, MD 2020-11-04
A phase II trial to evaluate MT-2766 in the treatment of subjects with COVID-19 Coronavirus disease 19 infection MT-2766 alone TLR-9 agonist Medicago Inc 2020-11-01 Phase 2 Clinical Planned 0 2020-10-29
Survival Rates and Longterm Outcomes After COVID-19 Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia ICU treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Oslo University Hospital The Research Council of Norway Norway 2020-09-16 2022-09-30 135310, NCT04601090 Phase Not Applicable Recruiting 1 24 Months 250 Kristin Hofsø, PhD 2020-10-29
Functional Recovery of Hospitalized Patients With COVID-19: The COREG Extension Study Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) McMaster University Canada 2020-06-09 2021-09-30 COREG-EXTENSION_14567, NCT04602260 Phase Not Applicable Recruiting 1 15 Months 211 Hope Morrison, BA, Marla K Beauchamp, PhD 2020-10-31
A trial to evaluate AK-119 for the treatment of patients with mild to moderate COVID-19 Coronavirus disease 19 infection AK-119 alone CD73 antagonist Akeso Biopharma Inc US Phase Not Applicable Not yet recruiting 1 2020-10-28
CCP Cancer UK Companion Study Coronavirus disease 19 infection, Hematological neoplasm, Solid tumor The Clatterbridge Cancer Centre NHS Foundation Trust The University of Liverpool, University of Edinburgh, University of Oxford UK 2020-10-31 2022-10-31 C1147, NCT04603105 Phase Not Applicable Not yet recruiting 2 24 Months 9000 Carlo Palmieri, Lance Turtle, Michael Stacckpoole, Bsc, Molly Mcevoy 2020-11-03
Be-Home-Kids: Feasibility and Effectiveness of Home-behavioral Program for Adolescents With Migraine Coronavirus disease 19 infection, Migraine, Migraine without aura Mindfulness by Smartphone alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Fondazione IRCCS Istituto Neurologico Carlo Besta Italy 2020-09-15 2021-12-31 BE-HOME-KIDS, Be-Home-Kids, NCT04604977 Phase Not Applicable Recruiting 1 15 Months 25 Licia Grazzi, Licia Grazzi, MD, Renato Mantegazza, MD 2020-10-30
Clinic-based HPV and COVID-19 Vaccine Promoting Intervention for AfAm Adolescents in Alabama Coronavirus disease 19 infection, Papillomavirus infection COVID-19 Vaccine alone, HPV vaccine alone, HPV vaccine uptake behavior and reducing sentiments alone Healthy volunteers accepted, Adolescents (13-17 yrs) University of Alabama at Birmingham US 2021-01-01 2023-06-30 MISP #60590, NCT04604743 Phase Not Applicable Not yet recruiting 1 30 Months 4 Henna Budhwani 2020-10-29
DUO-EF-19: Point of Care Artificial Intelligence Tool for Heart Failure Diagnosis Cardiac failure, Coronavirus disease 19 infection artificial intelligence electrocardiogram alone, cardiac MRI alone, digital stethoscope alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Imperial College London 2021-02-01 2022-10-01 285417, DUO-EF-19, NCT04601415 Phase Not Applicable Not yet recruiting 0 20 Months 1500 2020-10-29
Phase II Study of Bemcentinib for the Treatment of COVID-19 in Hospitalized Patients Coronavirus disease 19 infection bemcentinib alone, standard of care alone Axl tyrosine kinase receptor inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) BerGenBio AS, IQVIA RDS (India) Pvt Ltd India 2020-10-20 BGBC020, CTRI/2020/10/028602 Phase 2 Clinical Recruiting 7 120 Dr Atul Arvind Joshi, Dr John Ramapuram, Dr Maheshkumar Sutariya, Dr Manojkumar Chopada, Dr Naresh Kumar, Dr Prathibha Pereira, Dr Sambit Sahu, Suneela Thatte 2020-11-03
Online cognitive behavioral therapy for distress in people who lost a loved one during the corona pandemic: A randomized waitlist-controlled trial Acute stress disorder, Coronavirus disease 19 infection, Major depressive disorder, Post traumatic stress disorder online cognitive behavioral therapy alone, psychoeducation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universiteit Utrecht Netherlands 2020-07-01 2022-07-01 METC 20-446, NL8993 Phase Not Applicable Recruiting 1 24 Months 52 Lyanne Reitsma 2020-10-30
Digital Health Literacy Intervention for Disadvantaged Women During Corona Coronavirus disease 19 infection Digital Health Literacy Intervention alone, Health literacy video tutorial alone, Monthly group virtual meetings and Whatsapp group alone, Provision and guidance of a self-management alone, Virtual one-on-one weekly meetings alone Female, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Forman Christian College Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital, doctHERs 2020-11-01 2021-06-01 FORMANCHRISTIANC, NCT04603092 Phase Not Applicable Not yet recruiting 0 7 Months 1000 Sara Rizvi Jafree 2020-11-05
Nurse Leadership for Hospital Infection Control Coronavirus disease 19 infection, Infectious disease Intervention for COVID-19 preventive protocols alone, digital communication of written material alone, monthly online training and discussion alone Healthy volunteers accepted, Female Forman Christian College King Edward Medical University, Shahid Hussain Foundation, Shalamar Medical and Dental College 2020-11-01 2021-03-01 NCT04603079, NURSELEADERSHIP Phase Not Applicable Not yet recruiting 0 4 Months 200 Sara Rizvi Jafree 2020-11-05
EN-COVID-19: Enduring Happiness and Continued Self-Enhancement (ENHANCE) for COVID-19 Anxiety disorder, Coronavirus disease 19 infection, Insomnia, Post traumatic stress disorder Enduring Happiness and Continued Self-Enhancement (ENHANCE) for COVID-19 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of British Columbia University of Utah, University of Virginia Canada 2020-10-14 2020-12-31 EN-COVID-19, NCT04602832, UNIVERSITY OF BRITISH COLUMBIA Phase Not Applicable Recruiting 1 2 Months 350 Lesley Lutes 2020-11-05
How Does Mindfulness Meditation Buffer the Negative Effects of Pain and Suffering in the COVID-19 World? (Healthy Sample) Coronavirus disease 19 infection, Pain Book listening alone, Mindfulness meditation alone, focussed-attention mindfulness meditation alone, sham mindfulness meditation alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Queensland University of California San Diego, University of Sydney Australia 2020-10-31 2021-03-31 2019000347-S4C, NCT04602312 Phase Not Applicable Not yet recruiting 1 5 Months 624 Jonathan Davies, MSc, Melissa Day, PhD 2020-10-29
How Does Mindfulness Meditation Buffer the Negative Effects of Pain and Suffering in the COVID-19 World? (Pain Sample) Coronavirus disease 19 infection, Pain Mindfulness meditation alone, focussed-attention mindfulness meditation alone, sham mindfulness meditation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Queensland University of California San Diego, University of Sydney Australia 2020-10-31 2021-03-31 2019000347-S4P, NCT04602286 Phase Not Applicable Not yet recruiting 1 5 Months 292 Jonathan Davies, MSc, Melissa Day, PhD 2020-10-29
Physiotherapist-led Exercise Within Cardiac Rehabilitation and Paroxysmal Atrial Fibrillation and COVID-19 Atrial fibrillation, Coronavirus disease 19 infection Physiotherapist-led exercise-based cardiac rehabilitation alone, Threshold Inspiratory Muscle Trainer (Respironics Inc) alone, central circulatory exercise alone, inspiratory muscle training alone, muscle exercise alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Vastra Gotaland Region Sweden 2021-01-31 2025-10-31 273293, NCT04600713 Phase Not Applicable Not yet recruiting 1 57 Months 180 Maria Borland, PhD RPT, Åsa Cider, PhD RPT 2020-11-03
STAMP: Strategies to Assist With Management of Pain Coronavirus disease 19 infection, Lower back pain Mindfulness Meditation alone, usual care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Wisconsin-Madison Patient Centered Outcome Research Institute US 2017-06-30 2021-07-15 2017-0353, A532007, NCT03115359, SMPH/FAMILY MED/FAMILY MED, STAMP Phase Not Applicable Recruiting 4 48 Months 766 Aleksandra E Zgierska, MD PhD, Amy Watson, BS, Bruce P Barrett, MD PhD, Cindy A Burzinski, MS, Eric Garland, PhD, Lauren Papianou, BS, Robert Edwards, PhD 2020-10-30
Adaptive, randomized, open, controlled study to assess the efficacy and safety of Nobazit, film-coated tablets, 250 mg (JSC Avexima, Russia) in the treatment of hospitalized patients with an infection caused by the SARS-CoV-2 virus (COVID-19) Coronavirus disease 19 infection enisamium iodide (Nobazit), Avexima alone Avexima OJSC Russian Federation 2020-10-27 2021-06-10 Nobazit-COVID-19-T-III-2020 Phase 3 Clinical Status not specified 13 7 Months 160 2020-10-29
Odorat-Covid: Evaluation of Two Methods of Olfactory Rehabilitation in Post-viral Loss of Smell: Classic and Intensive Coronavirus disease 19 infection, Dysomia, Olfactory nerve disorder smell the odors of the olfactory rehabilitation kit according to the intensive method alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Hospital, Nancy, France France 2020-07-01 2021-01-01 2020PI098, NCT04598763, Odorat-Covid Phase Not Applicable Recruiting 1 6 Months 80 Duc Trung NGUYEN, Duc Trung NGUYEN, MD, PhD, MPH, Julie Lecomte 2020-10-31
COVID-CARE: COVID-19, Chronic Adaptation and Response to Exercise Coronavirus disease 19 infection Aerobic Exercise Training alone, Education alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institutes of Health Clinical Center US 2020-11-10 2023-12-31 000102-CC, 10000102, COVID-CARE, NCT04595773 Phase 1/Phase 2 Clinical Not yet recruiting 1 37 Months 90 COVID-CARE Rehab Team, Leighton Chan, M.D. 2020-11-06
Detection of COVID-19 Using Breath Analysis - Validation Study (COVID-19) Coronavirus disease 19 infection Breath biopsy analysis alone, RT-PCR alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Scentech Medical Technologies Ltd Israel 2020-11-12 2021-02-28 COV-2-SMC-2020, NCT04602949 Phase Not Applicable Not yet recruiting 1 3 Months 4000 Natalie Dror, PhD, Shai Efrati, Shai Efrati, MD 2020-10-30
ANTICOV EPI: Factors affecting transmission of SARS-CoV-2 in Households of SARS-CoV-2 patients in Sub-Saharan Africa Ancillary study of the ANTICOV Study: An open-label, multicenter, randomized, adaptive platform trial of the safety and efficacy of several therapies, including antiviral therapies, versus control in mild / moderate cases of COVID-19 Coronavirus disease 19 infection Hydroxychloroquine alone, lopinavir + ritonavir alone HIV protease inhibitor Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Barcelona Institute for Global Health, Bernhard-Nocht-Institute for Tropical Medicine, Drugs for Neglected Diseases Initiative, Ifakara Health Institute Mozambique, Ghana, Kenya, Equatorial Guinea 2020-11-02 2021-06-01 ANTICOV EPI, PACTR202010718451278 Phase Not Applicable Not yet recruiting 4 7 Months 2800 James Arkinstall, MarcAlain Widdowson, Nathalie Strub Wourgaft 2020-10-29
Early Detection of COVID-19 Using Breath Analysis Coronavirus disease 19 infection ReCIVA breath sampler alone, breath biopsy sampling alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Scentech Medical Technologies Ltd Israel 2020-09-22 2020-12-30 COV-2-IDF, NCT04602884 Phase Not Applicable Suspended 1 3 Months 50 Natalie Dror, PhD 2020-11-03
VBW: Virtual Assisted Living Coronavirus disease 19 infection, Muscle weakness ambient assisted living system scanning alone, virtual assisted living preventive care alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) BKK VBU Bahn BKK, DAK Gesundheit, HOWOGE Wohnungsbaugesellschaft mbH, Innovationsausschuss beim Gemeinsamen BundesausschussProjektträger DLR, Philips Medical Systems Technologies Ltd Germany 2020-11-02 DRKS00023171, EA1/032/20, VBW Phase Not Applicable Not yet recruiting 1 207 Anne Gersitz, Johanna Nordheim 2020-11-05
Training Load Management in Three Professional Tennis Players During COVID-19 Lockdown: a Case Series Study Coronavirus disease 19 infection training load monitoring alone Healthy volunteers accepted, Male Kine Kinesiologia Deportiva y Funcional Argentina 2019-12-15 2021-01-15 NCT04602637, TLT01 Phase Not Applicable No longer recruiting 1 13 Months 3 Diego Mendez, PT 2020-10-29
Knowledge Attitude and Practice of Hand hygiene among Nursing Assistants and Trolley workers in a COVID-19 care units Coronavirus disease 19 infection questionnaire alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Government Medical College Kannur India 2020-11-05 CTRI/2020/10/028600 Phase Not Applicable Not yet recruiting 1 100 Dr Venugopalan A K 2020-10-29
CoPa: Handling and coping with the corona pandemic (Covid-19) and its physical and psychological effects Coronavirus disease 19 infection, Psychiatric disorder Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Lubeck Universitätsklinikum Schleswig-Holstein Germany 2020-04-05 20-118, CoPa, DRKS00023393 Phase Not Applicable Recruiting 1 5000 Elke Peters 2020-11-05
Factors Associated with Covid-19 Infection in Kinta District, Perak: A Case-Control Study Coronavirus disease 19 infection KINTA DISTRICT HEALTH OFFICE Malaysia 2021-01-01 2021-02-28 56860, NMRR-20-2286-56860 Phase Not Applicable Not yet recruiting 1 2 Months Dr Asraf Ahmad bin Qamruddin 2020-11-05
Covid-19 and Major Organ Thromboembolism: Manifestations in Neurovascular and Cardiovascular Systems Cardiovascular disease, Cerebrovascular disease, Coronavirus disease 19 infection, Thromboembolism Hospital Kuala Lumpur Malaysia 2020-10-23 2020-10-31 56982, NMRR-20-2283-56982 Phase Not Applicable Status not specified 1 Dr Presaad Pillai A/L Perianen 2020-10-28
The evaluation of efficacy of favipiravir in patients with mild-to-moderate COVID-19 Coronavirus disease 19 infection favipiravir (Dr. Abidi Pharmaceutical Co) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dr.Abidi's Pharmaceutical Laboratories Iran 2020-10-31 IR.TUMS.IKHC.REC.1399.215, IRCT20201005048936N1 Phase 3 Clinical Recruiting 3 126 Ali Rakei, Ayat Ahmadi, Mahboubeh Hajabdolbaghi, Mahshid Talebi Taher, Masoud Mardani 2020-11-02
COP20: Convalescent Plasma in the Treatment of Covid-19 Coronavirus disease 19 infection, Respiratory disease convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Skåne University Hospital Sweden 2020-04-25 2022-02-28 COP20, COVID CONVALESCENT PLASMA, NCT04600440 Phase 2 Clinical Recruiting 1 22 Months 100 Magnus Rasmussen, MD, Prof, Maria N Lundgren, MD, Mona Landin-Olsson, MD, Prof 2020-10-30
Early Detection of COVID-19 Using Breath Analysis - Feasibility Study Coronavirus disease 19 infection ReCIVA Breath Sampler alone, breath biopsy sampling alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Scentech Medical Technologies Ltd Israel 2020-07-03 2021-01-30 COV-2-2020, NCT04602871 Phase Not Applicable Recruiting 2 6 Months 108 David Shitrit, MD, Natalie Dror, PhD, Victor Novac, MD 2020-11-05
Mechanically assisted Airway clearence COVID -19 Coronavirus disease 19 infection mechanically assisted airway clearance alone Hospital Sungai Buloh Malaysia 2020-11-02 2021-07-01 55173, NMRR-20-2280-55173 Phase Not Applicable Status not specified 1 8 Months DR AKMAL HAFIZAH ZAMLI, swarna lata krishnabahawan 2020-10-29
DISH19: Dietary supplements use among health-care workers during the COVID-19 pandemic in Malaysia: a cross-sectional study Coronavirus disease 19 infection Dietary supplements alone Seberang Jaya Hospital Malaysia 2020-12-01 2021-06-30 56853, DISH19, NMRR-20-2275-56853 Phase Not Applicable Status not specified 1 7 Months Dr Looi Irene, Lee Heoy Teng 2020-10-28
OCTA Study: Retinal Vascular Changes in SARS-CoV-2 Patients Coronavirus disease 19 infection optical coherence tomography angiography alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universita degli Studi di Napoli Federico II Italy 2020-09-20 2020-10-22 2020/03, NCT04601012 Phase Not Applicable Completed 1 1 Month 40 Gilda Cennamo 2020-10-29
HEPMAB: Clinical Efficacy of Heparin and Tocilizumab in Patients With Severe COVID-19 Infection: a Randomized Clinical Trial Coronavirus disease 19 infection Variable regimens including enoxaparin sodium , heparin , tocilizumab Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Sao Paulo Conselho Nacional de Desenvolvimento Cientifico e Tecnologico - CNPq Brazil 2020-10-20 2021-12-31 5057/20/086, HEPMAB, NCT04600141 Phase 3 Clinical Not yet recruiting 1 14 Months 308 Lucas TC Ribeiro, Ludhmila A Hajjar, MD, PhD 2020-10-30
COVID-19 Tests: Nasopharyngeal Swab versus Saliva Collected With Salivette Cortisol for Viral RNA Sampling for RT-qPCR Coronavirus disease 19 infection Kylt detection kit alone, Salivette alone, TaqPath COVID-19 CE-IVD RT-PCR kit alone, cobas SARS-CoV-2 PCR test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Boehringer Ingelheim International GmbH 2020-10-20 2020-11-13 0352-2150, NCT04599959 Phase Not Applicable Not yet recruiting 0 80 2020-10-30
ComICU: Communication in ICU During COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) NMC Specialty Hospital United Arab Emirates 2020-11-01 2020-12-31 COMICU, ComICU, NCT04602351 Phase Not Applicable Not yet recruiting 1 2 Months 200 Gunjan Chanchalani, MD FNB, Prashant Nasa, Prashant Nasa, MD EDICM 2020-10-29
Venous Thromboembolism in Patients with COVID-19 in Japan Study Coronavirus disease 19 infection, Thromboembolism Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kuwana East Medical Center Japan 2020-11-01 UMIN000042235 Phase Not Applicable Recruiting 1 200 Norikazu Yamada, Yugo Yamashita 2020-10-29
Long-term, Follow-up Findings of Inpatients for COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia Cardiopulmonary exercise testing alone, spirometry alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Koç University Hospital Turkey 2020-10-15 2021-03-01 2020.188.IRB1.056, NCT04599998 Phase Not Applicable Recruiting 1 4 Months 37 Benan Çağlayan, Prof Dr, Fatma Işıl Uzel, MD 2020-11-06
PRESECO: The Prevent Severe COVID-19 (PRESECO) Study Coronavirus disease 19 infection favipiravir alone RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Appili Therapeutics Inc US 2020-11-30 2021-10-31 ATI0220, NCT04600895, PRESECO Phase 3 Clinical Not yet recruiting 1 11 Months 826 2020-10-29
Co-CAT: Child anxiety treatment in the context of COVID-19 Anxiety disorder, Coronavirus disease 19 infection online psychological intervention (OSI) alone, therapist support alone Preschool Children (2-5 yrs), Children (6-12 yrs) University of Oxford United Kingdom Research & Innovation UK 2020-09-01 2021-08-31 Co-CAT, IRAS 288074, CPMS 46902, ISRCTN12890382 Phase Not Applicable Not yet recruiting 2 12 Months 560 Mrs Taylor 2020-10-30
The protective effect of powered air purifying respirators during chest compressions: A simulation study Coronavirus disease 19 infection Mask Fitting Tester ((SIBATA Scientific Technology Ltd) alone, powered air purifying respirator (PAPR) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Nagoya University Nakatani foundation Japan 2020-12-01 UMIN000042239 Phase Not Applicable Not yet recruiting 1 54 Yukari Goto 2020-10-29
An essential research study to advance the use of telehealth for rehabilitation in response to public health crises such as the COVID-19 pandemic Brain injury, Coronavirus disease 19 infection, Spinal cord injury, Stroke telehealth for rehabilitation alone Brooks Rehabilitation Clinical Research Center, Inc Madonna Rehabilitation Hospital, Mary Free Bed Rehabilitation Hospital US Phase Not Applicable Recruiting 3 Dr. Judith Burnfield, Dr. Raine Osborne, Jason Peoples, Kenneth Ngo, MD 2020-10-27
Assessment of SARS CoV-2 seroprevalence and clinical profiling of COVID Unsuspected patients attending Otorhinolaryngology Department at AIIMS Jodhpur Coronavirus disease 19 infection IgM and IgG antibody testing alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) AIIMS Jodhpur India 2020-11-02 CTRI/2020/10/028598 Phase Not Applicable Not yet recruiting 1 50 Dr Amit Goyal, Dr Nitika Goyal 2020-10-29
The Effects of Narrative Exposure Therapy on COVID-19 Patients with Post-Traumatic Stress Disorder: A Randomized Controlled Trial Coronavirus disease 19 infection, Post traumatic stress disorder narrative exposure therapy alone Xiangyang Central Hospital China 2020-02-28 ChiCTR2000039369 Phase 0 Clinical No longer recruiting 2 111 Fan Ying 2020-10-29
The clinical characteristics and the etiology of COVID-19 infected patients with myocardial damage Coronavirus disease 19 infection, Heart injury Tongji Hospital, Huazhong University of Science and Technology, Tongji Medical College China 2020-10-30 ChiCTR2000039364 Phase Not Applicable Not yet recruiting 1 200 Cheng Wang, FengZhu, ZhouMin 2020-10-28
An open-label, prospective study to evaluate RLF-100 in patients admitted to an intensive care unit (ICU) with critical COVID-19 and respiratory failure Coronavirus disease 19 infection, Respiratory failure aviptadil (inhaled, sarcoidosis/acute lung injury/acute respiratory distress syndrome associated COVID-19), Relief Therapeutics Holding alone Adrenergic receptor antagonist, VIP receptor agonist NeuroRx Inc, Relief Therapeutics Holding AG Phase 2 Clinical Status not specified 0 2020-10-26
A trial to evaluate PGX-YBG for the treatment of patients with COVID-19 Coronavirus disease 19 infection PGX-YBG alone Ceapro Inc Phase Not Applicable Planned 0 2020-10-26
EAT COVID: An investigator initiated, randomized, Phase II clinical trial evaluating its eftilagimod alpha (“efti” or “IMP321”) in hospitalized patients with COVID-19 Coronavirus disease 19 infection eftilagimod alfa alone, standard care alone HLA class II antigen stimulator Immutep Ltd University Hospital Pilsen Czech Republic EAT COVID Phase 2 Clinical Recruiting 1 110 Dr. Dalibor Sedlacek, Dr. Marek Nalos,, Martin Matejovic 2020-10-26
A phase Ib clinical study to assess ProTrans in the treatment of subjects with COVID-19 Coronavirus disease 19 infection ProTrans alone NextCell Pharma AB Karolinska Trial Alliance Sweden Phase 1b Clinical Not yet recruiting 1 9 Doctor Tomasz Oldak, Professor Dominique Farge, Professor Edvard Smith, Professor Farge, Professor Josefin Sundh 2020-11-04
SARS-CoV-2 (COVID-19) Immune Surveillance Among a Population Based Sample of Adults in Florida Coronavirus disease 19 infection SARS-CoV-2 antibody analysis alone, Weck-cel swab collection alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) H Lee Moffitt Cancer Center and Research Institute Merck Sharp & Dohme Corp US 2020-10-09 2022-10-09 MCC-20635, NCT04596579 Phase Not Applicable Recruiting 2 24 Months 1200 Anna R Giuliano, PhD 2020-10-27
oXAKI-COV: Efficacy and Safety of a Highly Selective Semipermeable Membrane (AN69 oXiris) versus (Standard AN69) in COVID-19 Coronavirus disease 19 infection, Inflammatory disease, Renal injury AN69 oXiris alone, continuous renal replacement therapy alone, vasopressor therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Instituto Nacional de Ciencias Medicas y Nutricion Mexico 2020-10-02 2022-03-30 NCT04597034, NMM-3401-20-20-1, oXAKI-COV Phase Not Applicable Recruiting 1 17 Months 35 Mauricio Arvizu-Hernández, MD, Olynka Vega Vega, MD, Olynka Vega-Vega, MD, Ricardo Correa Rotter, MD, Ricardo Correa-Rotter, MD 2020-10-28
Vitamin D3 Supplementation to Prevent Respiratory Tract Infections Coronavirus disease 19 infection, Respiratory tract infection vitamin D, Cooper alone Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The Cooper Health System The Won Sook Chung Foundation 2020-10-31 2021-11-30 20-455, NCT04596657 Phase Not Applicable Not yet recruiting 0 13 Months 2099 Noud van Helmond, MD 2020-11-05
Study to Evaluate Efficacy and Safety of 'Viracide' in the Management of Corona Virus Disease 2019 (COVID-19) Coronavirus disease 19 infection ViraCide alone, standard of care alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) ProRelix Services LLP India 2020-09-16 2021-01-30 NCT04596085, NS-VC-CT01-20 Phase Not Applicable Recruiting 2 4 Months 124 Dr Ninad Naik, MD(Ayurveda), Dr. A Gopal Rao, MD Medcine, Dr. A Gopal Rao, MD(Med), Dr.Mahir Abduldaim, Dr.Ninad Naik, MD(Ayurveda), Muralidhar Gudla, Niranjan Andhalkar, Sohal Pendse 2020-11-05
APCC-19: Chemoprevention Clinical Trial of COVID-19: Hydroxychloroquine Post Exposure Prophylaxis Coronavirus disease 19 infection hydroxychloroquine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Regional Center for Disease Control and Prevention Farhat Hached University Hospital, Fattouma Bourguiba University Hospital Jordan 2020-10-27 2021-01-31 APCC-19, APCC-19, NCT04597775 Phase 2/Phase 3 Clinical Not yet recruiting 1 3 Months 93 Amer A Amous, MD, Munir A Abu-Helalah, PhD, Munir Abu-Helalah, PHD, Wissem Hachfi, MD 2020-11-05
Predicting the role of resilience, reactance, social solidarity and positive schemas on Pandemic-related Anxiety Anxiety disorder, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) LVR-Klinikum DüsseldorfKliniken der Heinrich-Heine-Universität Düsseldorf Germany 2020-11-01 2020-1071, DRKS00023321 Phase Not Applicable Not yet recruiting 1 85 Milenko Kujovic 2020-10-29
Prevalence and Temporal Evolution of Chest Radiographic Findings in Filipino Patients with Coronavirus Disease 2019 (COVID-19) Coronavirus disease 19 infection chest radiographic findings alone University of the Philippines Philippines 2020-05-15 2021-01-15 PHRR201012-003027 Phase Not Applicable No longer recruiting 1 8 Months Jarold P. Pauig, Johanna Patricia Adevoso-Cañal, Julian A. Santos, Rosanna E. Fragante 2020-11-06
The Knowledge, Attitudes and Practices of Resident Physicians in Southern Philippines Medical Center, Davao City Philippines towards COVID-19: a cross-sectional study Coronavirus disease 19 infection Knowledge levels, attitudes and practices alone Southern Philippines Medical Center Philippines 2020-11-01 2020-12-01 PHRR201012-003017 Phase Not Applicable Not yet recruiting 1 1 Month Gleno Lon Q. Llamera, Pilar Mynthia B. Vicente, Shera Elefante 2020-10-27
VTE-COVID-19: Non-invasive Prognostication of COVID-19 Patients by Use of Biomarkers in Exhaled Breath Condensate Coronavirus disease 19 infection, Lung injury, Respiratory insufficiency exhaled breath condensate analysis alone, metabolomics analysis alone, proteomics analysis alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Aalborg Universitetshospital Aarhus University Hospital Skejby Denmark 2020-09-19 2021-10-01 ILG-VTE-COVID-19-2020, N-20200069, NCT04598620, VTE-COVID-19 Phase Not Applicable Recruiting 2 12 Months 50 Inger L Gade, MD, PhD, Lise T Elkjær 2020-11-02
Cytokine Storm Among Bangladeshi Patients With COVID-19 Coronavirus disease 19 infection, Inflammatory disease biological sampling alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry International Centre For Diarrhoeal Disease Research, Bangladesh Bangladesh 2020-10-31 2021-06-30 20084, ICDDR,B, NCT04598334 Phase Not Applicable Not yet recruiting 1 8 Months 75 Mohammod J Chisti, MBBS, PhD, Mohammod J Chisti, MBBS,PhD, Monira Sarmin, Monira Sarmin, MBBS, Monira Sarmin, MBBS, MCPS, Tahmeed Ahmed, MBBS, PhD 2020-10-30
Safety of Sofosbuvir/Daclatasvir in outpatients with COVID-19 Coronavirus disease 19 infection Sovodak, Fanavaran Rojan Mohaghegh Daru Co alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tehran University of Medical Sciences International Treatment Preparedness Coalition Iran 2020-10-24 IR.TUMS.DDRI.REC.1399.024, IRCT20200128046294N3 Phase 1/Phase 2 Clinical Recruiting 1 50 Anahita Sadeghi, Neda Alijani, Shahin Merat 2020-10-28
GlobalSurg-CovidSurg Week: Batangas Medical Center data Coronavirus disease 19 infection Batangas Medical Center Philippines 2020-10-12 2021-04-12 PHRR201014-003031 Phase Not Applicable Not yet recruiting 1 6 Months Amabelle A. Moreno, MD 2020-11-05
Evaluation of the combination Ivermectin and Azithromycin as treatment in outpatients with COVID-19. Controlled clinical trial Coronavirus disease 19 infection ivermectin alone, azithromycin plus ivermectin Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Respiratory Diseases, Mexico Mexico 2020-11-03 C29-20 Phase 2 Clinical Status not specified 1 306 Arnoldo Aquino 2020-10-28
AcNT-COVID19: Immune Responses to COVID-19; Isolation of Neutralizing Antibodies for Therapeutics and Vaccine Coronavirus disease 19 infection Blood sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Grenoble Commissariat a l`Energie Atomique France 2020-04-30 2021-09-30 2020-A00904-35, 38RC20.132, AcNT-COVID19, NCT04596098 Phase Not Applicable Recruiting 2 17 Months 120 Benjamin NEMOZ, PHD, Djamila DURIN, engineer, Pascal POIGNARD, PHD, Pierre AUDOIN, engineer 2020-10-27
Antiviral Activity and Safety of Remdesivir in Bangladeshi Patients With Severe Coronavirus Disease (COVID-19) Coronavirus disease 19 infection, Respiratory distress syndrome remdesivir alone, standard of care alone COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Beximco Pharmaceuticals Ltd Bangladesh 2020-09-04 2021-01-31 BEX-06001, NCT04596839 Phase 2 Clinical Recruiting 1 4 Months 60 Dr. Md. Alimur Reza, Dr. Md. Alimur Reza, MBBS, MPH, Major General Md. Azizul Islam, Major General Md. Azizul Islam, MBBS, FCPS 2020-10-28
CAPTURE-2: Research and Evaluation of LumiraDx SARS-CoV-2 (COVID-19) Point of Care Ab Test Coronavirus disease 19 infection LumiraDx alone, SARS-CoV-2 Ab test alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) LumiraDx UK Ltd US 2020-08-20 2022-12-31 CAPTURE-2, NCT04597047, S-CLIN-PROT-0031 Phase Not Applicable Recruiting 4 28 Months 200 David Craig, Matthew Morgan, Melanie Hoppers, Vicki Kalen, William Simon 2020-10-28
NanoDxCoV19: Exploration of Feasability of Blood and Saliva Proteomic Analysis Through Harvesting by Silica Matrix Coronavirus disease 19 infection, Respiratory tract infection proteomic analysis alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Grenoble France 2020-10-15 2021-12-31 38RC20.289, NCT04597216, NanoDxCoV19 Phase Not Applicable Recruiting 1 14 Months 200 olivier EPAULARD 2020-10-28
NICOVID-REA: Evaluation of the Efficacy of Nicotine Patches in SARS-CoV2 (COVID-19) Infection in Intensive Care Unit Patients Coronavirus disease 19 infection nicotine alone Nicotinic acetylcholine receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris 2020-10-31 2021-10-31 2020-003723-42, APHP200537, NCT04598594, NICOVID-REA Phase 3 Clinical Not yet recruiting 0 12 Months 220 2020-10-27
Expanded Access Study of Exebacase in COVID-19 Patients With Persistent MRSA Bacteremia Coronavirus disease 19 infection, Endocarditis, MRSA infection antistaphylococcal antibiotic therapy alone, exebacase alone Hydrolase stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) ContraFect Corp US 2020-10-26 CF-301-107, NCT04597242 Phase Not Applicable Recruiting 1 Medical Director, ContraFect 2020-10-28
Schools Transmission Study (COVID-19 and Scarlet Fever) Coronavirus disease 19 infection, Group A Streptococcus infection biological sampling alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) Imperial College London Action Medical Research, National Institute for Health Research (NIHR) UK 2017-09-01 2025-03-31 CPMS 37059, IRAS 225006, ISRCTN13773960 Phase Not Applicable Recruiting 1 91 Months 344 Mrs Kerri Hill-Cawthorne, Prof Sriskandan 2020-10-28
A study to assess safety and efficacy UNI-91103 in patients affected with covid-19 Coronavirus disease 19 infection UNI-91103 alone Healthy volunteers accepted UNION therapeutics Phase Not Applicable Planned 0 44 2020-10-26
Evaluation of the Possible Vertical Transmission of SARS-CoV-2 Through Study of Amniotic Fluid and Chorionic Villi of Affected Pregnant Women for the COVID-19 Coronavirus disease 19 infection Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundacio Institut De Recerca De L'Hospital De La Santa Creu I Sant Pau Spain 2020-08-08 2022-01-23 IIBSP-COV-2020-59, NCT04598347 Phase Not Applicable Recruiting 1 17 Months 225 Obdulia Alejos Abad, PhD, MD, Obdulia Alejos, MD 2020-10-28
A prospective study to evaluate the accuracy of Cue COVID-19 Test in the diagnosis of COVID-19 infection Coronavirus disease 19 infection Cue COVID-19 Test alone Mayo Clinic Foundation Phase Not Applicable Status not specified 0 2020-10-26
A pivotal, phase III study of plitidepsin in patients with COVID-19, who require hospitalization Coronavirus disease 19 infection plitidepsin alone Elongation factor 1 alpha 2 modulator, VEGF-1 receptor modulator PharmaMar SA Phase 3 Clinical Planned 0 2020-10-26
A study of association of chest X-ray with clinical severity in hospitalized COVID-19 patients Coronavirus disease 19 infection, Hypoxia, Respiratory distress syndrome chest X-ray alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kasturba hospital India 2020-10-31 CTRI/2020/10/028525 Phase Not Applicable Not yet recruiting 1 300 Nandakrishna B 2020-10-29
A phase III clinical trial of AT-527 to explore the potential use in patients outside of the hospital setting Coronavirus disease 19 infection AT-527 alone Hepatitis C virus NS5B polymerase inhibitor Atea Pharmaceuticals Inc, Roche Holding AG 2021-03-31 Phase 3 Clinical Planned 0 2020-10-27
Hematological and biochemical abnormalities parameters in the severity of COVID-19 Coronavirus disease 19 infection tocilizumab alone Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shree Krishna Hospital, pramukhswami medical college India 2020-10-30 CTRI/2020/10/028523 Phase Not Applicable Not yet recruiting 1 200 Dr Abdulrahman Amer, Dr Hitesh Shah 2020-10-27
COSEVAST study: To study the relationship of COVID-19 severity with blood vessels Cardiovascular disease, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Medical Sciences Patna India 2020-10-26 COSEVAST study, CTRI/2020/10/028489 Phase Not Applicable Not yet recruiting 1 75 Neeraj Kumar, Sanjeev Kumar 2020-10-29
RISEUP-PPD-COVID-19: Impact of COVID-19 Pandemic in Perinatal Mental Health Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder, Psychiatric disorder Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidade do Minho Bar-Ilan University, European University Cyprus, Havre Hospital, Instituto Presbiteriano Mackenzie, Instituto de Investigacion Biomedica de Malaga, Instituto de Saúde Pública da Universidade do Porto (ISPUP), King's College London, Kırklareli University, Mount Carmel Health System, Universidad Nacional De Educación A Distancia (UNED), Universidad de Huelva, Universidade Católica Portuguesa - Ucp, University of Athens, University of Coimbra, University of Malta, University of Sofia Israel, Portugal, Malta, Spain, Albania, Greece, Brazil, Bulgaria, France, Turkey, Chile, Cyprus, UK 2020-06-15 2021-06-15 NCT04595123, RISEUP-PPD-COVID-19, RISEUP-PPD-COVID-19 Phase Not Applicable Recruiting 13 12 Months 3900 Ana Mesquita, PhD, Ana Rita Carlos, Andry Christoforou, PhD, Angelique Picard, PhD, Camellia Hancheva, PhD, Claire Wilson, PhD, Eleni Vousoura, PhD, Emma Motrico, PhD, Erilda Ajaz, PhD, Ethel Felice, Dr, Pelin Dikmen-Yildiz, PhD, Rena Bina, PhD, Sandra M. Saldivia, PhD, Sara Dominguez, PhD, Vera Mateus, PhD 2020-11-06
The impact of COVID-19 pandemic on colorectal cancer therapy Colorectal tumor, Coronavirus disease 19 infection Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Uji-Tokushukai Medical Center Japan 2020-08-15 UMIN000042211 Phase Not Applicable No longer recruiting 1 123 Mizuno Rei 2020-11-06
NETSCOV TRIAL: Role of blood cellular mechanism in severity of COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences Patna India 2020-10-26 CTRI/2020/10/028488, NETSCOV TRIAL Phase Not Applicable Not yet recruiting 1 60 Abhyuday Kumar 2020-10-28
COVIDCOLLECT: Relationship Between Biological Profiles and Clinical Evolutions Within the Same Cluster COVID-19 Coronavirus disease 19 infection RT-PCR alone Healthy volunteers accepted University Hospital Clermont-Ferrand France 2020-11-30 2022-02-28 2020-A02381-38, COVIDCOLLECT, NCT04597736, RBPH 2020 HENQUELL Phase Not Applicable Not yet recruiting 1 15 Months 100 Cécile Henquell, Céclie Henquell, Etienne Merlin, Lise LACLAUTRE, Lise Laclautre, Magali Vidal, Marc Berger, Olivier Lesens 2020-10-30
CEMS: To Study the safety of remdesivir in COVID-19 Patients Coronavirus disease 19 infection remdesivir alone COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences Patna India 2020-10-30 CEMS, CTRI/2020/10/028487 Phase Not Applicable Not yet recruiting 1 100 Dr Aakanksha Priya, Dr Shruti Singh 2020-10-27
CONSERVE-HCW: Changes in Seroprevalence and Wellness Over Time in Healthcare Workers Coronavirus disease 19 infection bbott Architect SARS-CoV-2 IgG assay alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) St. Joseph's Hospital and Medical Center Chandler Regional Medical Center, Dignity Health, Mercy Gilbert Medical Center US 2020-06-10 2021-12-30 20-510-157-66-21, CONSERVE-HCW, NCT04595175 Phase Not Applicable Recruiting 1 18 Months 2000 Andrea B. Garcia, MBA, Andrea Garcia, MBA, Brian Tiffany, Brian Tiffany, MD, PhD, Jennine Zumbuhl, RN, MSHA 2020-10-28
COVID-RT-01: Low Dose Radiation Therapy for Severe-Acute-Respiratory-Syndrome-Coronavirus-2 (SARS-CoV-2), COVID-19 Coronavirus disease 19 infection low dose radiation therapy (1 Gray) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Basel Switzerland 2020-11-02 2021-11-30 2020-02047QU20PAPACHRISTOFILOU, COVID-RT-01, NCT04598581 Phase Not Applicable Recruiting 1 12 Months 22 Alexandros Papachristofilou, Dr. med., Martin Siegemund, Prof. Dr. med., Tobias Finazzi, Dr. med. 2020-11-05
LungMechCoV-19: Assessment of Lung Mechanics in COVID-19 Acute Respiratory Distress Syndrome Coronavirus disease 19 infection, Respiratory failure Impedance tomography alone, indirect calorimetry alone, right-heart catheterization alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Zurich 2020-10-20 2021-12-31 2020-01999, LungMechCoV-19, NCT04597853 Phase Not Applicable Not yet recruiting 0 14 Months 25 Philipp K Buehler, MD 2020-10-28
FIPPS: Trial of financial incentives for preventing postpartum return to smoking Coronavirus disease 19 infection, Nicotine dependence financial incentive alone Female, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Of Stirling UK 2018-02-01 2022-11-30 FIPPS, ISRCTN55218215, VERSION 6.0 Phase Not Applicable Recruiting 5 58 Months 900 Prof Ussher 2020-10-28
Challenges faced by PG students in conducting research Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kasturba Medical College and Hospital India 2020-10-26 CTRI/2020/10/028520 Phase Not Applicable Not yet recruiting 1 800 Divya Karanth 2020-10-27
Treatment of SARS-CoV-2 Virus Disease (COVID-19) in Humans With Hemopurifier Device Acute lung injury, Coronavirus disease 19 infection, Multiple organ failure, Respiratory distress syndrome, Respiratory failure, Septic shock Hemopurifier alone, arteriovenous fistula treatment alone, double-lumen hemodialysis catheter alone, extracorporeal therapy alone, graft treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Aethlon Medical Inc US 2020-10-31 2021-08-31 AEMD-2020-02, NCT04595903 Phase Not Applicable Not yet recruiting 2 10 Months 40 Lisa Boswell, Timothy C Rodell, MD, Usman Shah, MD 2020-10-31
A clinical study to assess AZD-7442 in the treatment of subjects with COVID-19 Coronavirus disease 19 infection AZD-7442 alone COVID19 Spike glycoprotein inhibitor AstraZeneca plc Biomedical Advanced Research and Development Authority (BARDA) Phase Not Applicable Planned 0 4000 2020-10-23
Impact of Covid-19 on mental health among health care workers Coronavirus disease 19 infection, Psychiatric disorder Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Indira Gandhi Medical College India 2020-12-01 CTRI/2020/10/028524 Phase 3 Clinical Not yet recruiting 1 632 Shabnum Thakur 2020-10-28
Yoga for COVID-19 Patients with mild symptoms Coronavirus disease 19 infection, Respiratory tract infection Yoga modules intervention alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mahatma Gandhi Memorial Medical College, Indore, Swami Vivekananda Yoga Anusandhana Samsthana Svyasa India 2020-11-02 CTRI/2020/10/028486 Phase 1 Clinical Not yet recruiting 1 50 Dr Satyapriya Maharana, Pragya Jain Shrimal 2020-10-27
Endoscopic Procedures of Children in the Normalization Process of Covid-19 Pandemic Coronavirus disease 19 infection, Gastrointestinal disease COVID-19 PCR test alone, chest radiography alone, endoscopy alone, thorax computed tomography alone Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Tepecik Training and Research Hospital Turkey 2020-06-01 2020-08-31 NCT04598256, TEPECIKTRH1 Phase Not Applicable Completed 2 3 Months 77 BETÜL AKSOY, MD, DİLEK YILMAZ ÇİFTDOĞAN, PROFESSOR, MAŞALLAH BARAN, PROFESSOR, YELİZ ÇAĞAN APPAK, MD, ŞENAY ONBAŞI KARABAĞ, MD 2020-11-03
Relation of lung disease and smoking with the severity of COVID-19 in a district hospital of Pune city, Maharashtra Chronic obstructive pulmonary disease, Coronavirus disease 19 infection, Nicotine dependence Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Byramjee Jeejeebhoy Govt Medical College and Sassoon General Hospitals India 2020-10-26 CTRI/2020/10/028470 Phase Not Applicable Not yet recruiting 1 489 Dr Malangori Parande, MINAL HATNAPURE 2020-10-29
Investigating the efficacy and safety of Myrtus nasal spray in controlling the symptoms of patients with mild COVID-19 Coronavirus disease 19 infection Myrtus inhalation spray alone, routine treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bagheiat-allah University of Medical Sciences Iran 2020-07-22 IR.BMSU.REC.1399.159, IRCT20080901001165N63 Phase 3 Clinical No longer recruiting 1 100 Gholamhosein Alishiri, Parisa Kianpour, Seyed Mohamad Javad Hosseini, Yunes Panahi 2020-10-27
Evaluation of short term outcomes of liver transplantation from COVID-19 positive deceased donors Acute liver failure, Coronavirus disease 19 infection liver transplantation alone Mashhad University of Medical Sciences Iran 2020-10-01 IR.MUMS.REC.1399.442, IRCT20200928048867N1 Phase Not Applicable Recruiting 1 10 Mohsen Aliakbarian, Mohsen Tafaghodi, Sara Saeidi Shahri 2020-10-28
CovidSat@Home: A randomized, controlled pilot trial investigating the feasibility and safety of monitoring patients with or at risk for cardiovascular disease who have symptoms suspected of COVID-19 by pulse oximetry at home Coronavirus disease 19 infection, Hypoxia home monitoring of blood oxygen levels alone, pulse oximeter alone, usual (primary) care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitair Medisch Centrum Utrecht Dutch Heart Foundation Netherlands 2020-11-01 2021-06-01 CovidSat@Home, NL8954 Phase Not Applicable Not yet recruiting 1 7 Months 50 Dorien Zwart 2020-10-27
EPICS-14: Point of Care Influenza screening and SARS-CoV-2 (COVID-19) testing in the Emergency Department Coronavirus disease 19 infection, Influenza virus infection COVID-19 testing alone, Influenza A/B point-of-care screening test alone, cobas Liat system alone, multiplex real-time polymerase chain reaction test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Charite Universitaetsmedizin Berlin Roche Molecular Systems Inc Germany 2019-12-17 DRKS00019207, EA2/204/19, EPICS-14, EPICS-14 Phase Not Applicable Recruiting 1 3000 Martin Mockel 2020-10-27
Yoga for COVID-19 healthcare workers Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection Yoga alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Swami Vivekananda Yoga Anusandhana Samsthana Svyasa India 2020-11-02 CTRI/2020/10/028485 Phase 1 Clinical Not yet recruiting 1 100 Dr Satyapriya Maharana, Pragya Jain Shrimal 2020-10-29
COVAED: Study of Edaravone as adjunctive treatment in COVID Coronavirus disease 19 infection edaravone alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Sparsh Foundation India 2020-10-29 COVAED, CTRI/2020/10/028472 Phase 2 Clinical Not yet recruiting 1 40 Dr John Paul M 2020-11-05
Systematic Review - COVID-19 Coronavirus disease 19 infection Corticosteroids therapy alone, tocilizumab alone Pulau Pinang Hospital Malaysia 2020-11-01 2021-11-01 56296, NMRR-20-2263-56296 Phase Not Applicable Status not specified 1 12 Months DR Sivasangari Subramaniam, Lim Phei Ching 2020-10-28
ASTERIX: An observational study to identify sub-groups of COVID-19 patients based on their demographic, clinical and laboratory profile, and to determine if these sub-groups can be used to predict severity of disease and response to therapy Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) NHS Greater Glasgow and Clyde National Institute for Health Research (NIHR), Scottish Government Health and Social Care Directorates UK 2020-04-01 2021-01-01 ASTERIX, CPMS 46231, IRAS 283151, ISRCTN66141262 Phase Not Applicable Recruiting 2 9 Months 600 Mrs Evans 2020-10-29
Relationships between physical activity during hospitalization and physical capacity after discharge from hospital in patients with COVID-19: a prospective, observational study Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Wakayama Medical University Japan 2020-11-15 UMIN000042214 Phase Not Applicable Not yet recruiting 1 40 Masakazu Minetama, Tadashi Sumiya 2020-10-27
Effect of the drug 'Immune'- an Ayurveda medication in COVID-19 patients Coronavirus disease 19 infection Variable regimens including Aswagandha , Devadaaru , Jeevanthi , Yashthimadu Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Sathayush Ayurvedic India Private Limited India 2020-11-02 CTRI/2020/10/028471 Phase 2 Clinical Not yet recruiting 1 50 DrSudha Bala, Sailaja Vani 2020-10-31
A phase Ib clinical trial to evaluate the safety, tolerance and preliminary immunogenicity of different doses of a novel coronavirus pneumonia (COVID-19) mRNA vaccine in population aged 18 to 59 years Coronavirus disease 19 infection, Viral pneumonia mRNA vaccine (Lipid Nano Particle, COVID-19), Walvax Biotechnology/Suzhou Abogen Biosciences alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Chinese Academy of Medical Military Sciences, Shulan (Hangzhou) Hospital, Suzhou Abogen Biosciences China 2020-10-28 2021-12-31 ChiCTR2000039212 Phase 1b Clinical Not yet recruiting 1 14 Months 1200 Lin Yuan, Shuyuan Yang 2020-11-06
Yoga for COVID-19 asymptomatic patients Coronavirus disease 19 infection Tele based yoga alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Swami Vivekananda Yoga Anusandhana Samsthana Svyasa India 2020-11-02 CTRI/2020/10/028566 Phase 1 Clinical Not yet recruiting 1 60 Dr Satyapriya Maharana, Pragya Jain Shrimal 2020-10-27
IND-02 for prevention against SARS-CoV-2 Infection: A Randomized, controlled study in moderate to high risk population Coronavirus disease 19 infection IND-02 alone ApoB editing catalytic polypeptide 3G modulator, HIV gp120 protein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Indus Biotech Pvt Ltd India 2020-10-29 CTRI/2020/10/028547, IND02-NASAL-PROPHYLAXIS Phase 2/Phase 3 Clinical Not yet recruiting 5 258 Dr A Venkateshwar Rao, Dr Deepak B Varade, Dr Kapil Patwardhan, Dr Manish Rajak, Dr Nidhi Anand, Dr Prasad Thakurdesai, Dr Sonali Nirhali 2020-10-28
High-flow nasal cannula oxygen in adult patients of COVID-19 admitted to intensive care units. Coronavirus disease 19 infection igh-flow nasal cannula oxygen therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Lok Nayak Hospital India 2020-10-28 CTRI/2020/10/028539 Phase Not Applicable Not yet recruiting 1 70 sukhyanti kerai 2020-10-27
Clinical trial of Ayurvedic Medicines in Patients with Asymptomatic and/or Mild Symptoms of COVID-19 Coronavirus disease 19 infection Chyawanprash alone, Immuncoction alone, Standard medicine therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) India 2020-10-22 CTRI/2020/10/028537, MHC/CT/20-21/011 Phase 2 Clinical Not yet recruiting 2 90 Dr Anurag Gupta, Prof NS Sengar 2020-10-27
Semen Analysis Changes in Covid-19 Positive patients Coronavirus disease 19 infection Semen analysis alone Healthy volunteers accepted, Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Assiut University Egypt 2020-05-01 2020-10-15 NCT04595240, SEMEN ANALYSIS POST COVID-19 Phase Not Applicable Completed 1 5 Months 100 ahmed a abdel moniem, md, mostafa kamel abdel rahman abdel aal 2020-11-04
ADDIMTCOVID: Inspiratory Muscle Training in COVID-19 Patients Coronavirus disease 19 infection PowerBreathe KHP2 alone, endurance training alone, inspiratory muscle training alone, interval training alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundação de Ensino e Pesquisa em Ciências da saude Conselho Nacional de Desenvolvimento Cientifico e Tecnologico - CNPq, Jbs Sa, University of Brasilia Brazil 2020-11-01 2021-06-30 ADDIMTCOVID, CNPQ092020, NCT04595097 Phase Not Applicable Not yet recruiting 1 8 Months 120 Vinicius Maldaner, Vinicius Zacarias Maldaner da silva 2020-10-27
Irbesartan and Oseltamivir treatment of COVID-19 infection Coronavirus disease 19 infection irbesartan plus oseltamivir Angiotensin II AT-1 receptor antagonist, Exo-alpha sialidase inhibitor Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Slagelse Hospital Denmark 2020-09-16 2020-001610-38, JAGG2020-1 Phase 4 Clinical Recruiting 1 80 2020-10-27
Treatment and followup outcomes of gynecological cancer patients treated with radiation therapy during lockdown phase of COVID pandemic Cancer, Coronavirus disease 19 infection radiation therapy alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tata Memorial Centre India 2020-10-30 CTRI/2020/10/028571 Phase Not Applicable Not yet recruiting 1 1500 Dr Supriya Chopra 2020-10-28
To study the effect of Vyaghradi Kashay tablet on COVID-19 patients Coronavirus disease 19 infection Vyaghradi Kashay alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ministry of Ayush Ayurvedic and Unani Tibbia College India 2020-11-05 CTRI/2020/10/028570 Phase 2/Phase 3 Clinical Not yet recruiting 1 30 Dr Manoj Shamkuwar, Dr Nitin Jindal 2020-10-23
Challenges for healthcare workers with infection control practices during COVID-19 pandemic Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) AIIMS Jodhpur India 2020-10-26 CTRI/2020/10/028569 Phase Not Applicable Not yet recruiting 1 200 Anuradha Sharma 2020-10-30
COVID-19: Study to Evaluate the Efficacy of COVID-19-0001-USR in Patients With Mild/or Moderate COVID-19 Infection in Outpatient Coronavirus disease 19 infection COVID-19-0001-USR alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Colombia 2020-11-02 2021-01-29 COVID-19, COVID19-0001-USR, NCT04595136 Phase 1/Phase 2 Clinical Not yet recruiting 1 2 Months 60 Carlos A Riveros, MD, Juan Jaller, MD 2020-10-23
Trends in suicide rates during the Covid-19 pandemic quarantine Coronavirus disease 19 infection, Suicide Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) UniversitätsKlinikum Leipzig Germany 2020-06-24 272/20-ek, DRKS00022536 Phase Not Applicable Recruiting 1 500 Daniel Radeloff 2020-10-24
Clinical Study to Evaluate the Effects of Disulfiram in Patients With Moderate COVID-19 Coronavirus disease 19 infection disulfiram (Antabuse) alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto Etica Saude Brazil 2020-10-31 2021-04-30 NCT04594343, SPR-001-201 Phase 2 Clinical Not yet recruiting 1 6 Months 200 Augusto Mota, MD/PhD, Wendy Cousin, PhD 2020-11-05
Dosing of Thromboprophylaxis and Mortality in Critically Ill COVID-19 Patients Bleeding, Coronavirus disease 19 infection, Respiratory failure, Thromboembolism dalteparin sodium alone, tinzaparin sodium alone Antithrombin III, Factor IIa antagonist, Factor Xa antagonist, Low molecular weight heparin Karolinska Institutet Sweden 2020-03-01 2020-10-15 NCT04593654, THROMBOPROPHYLAXIS COVID-19 Phase Not Applicable Completed 1 7 Months 257 Sandra Jonmarker, MD 2020-10-27
Teledermatology during the COVID-19 pandemic: A retrospective descriptive study Acne vulgaris, Coronavirus disease 19 infection, Eczema, Psoriasis, Skin cancer, Skin infection, Urticaria, Vasculitis, Venous insufficiency Southern Philippines Medical Center Philippines 2020-11-01 2020-12-01 PHRR201015-003037 Phase Not Applicable Recruiting 1 1 Month Anna Cristina L. Cuenca, Jen-Christina Segovia, MD, Lalaine R. Visitacion, MD, FPDS 2020-10-27
Evaluate Safety and Efficacy of RV Forte Capsule as an immunomodulator in adult Covid 19 positive patients Coronavirus disease 19 infection RV Forte alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) RV New Vision Healthcare Pvt Ltd India 2020-10-26 CTRI/2020/10/028568, MHC/CT/20-21/007 Phase 2 Clinical Not yet recruiting 1 60 Dr Gayatri Gnau, Dr V G Vaidya 2020-11-05
Virgin Coconut Oil (VCO) as a Potential Adjuvant Therapy in COVID-19 Patients Coronavirus disease 19 infection, Viral pneumonia virgin coconut oil alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Gadjah Mada Indonesia 2020-06-01 2020-12-31 002/05/2020, NCT04594330 Phase 2 Clinical Recruiting 4 7 Months 60 Desy NP, MD, Eko Purnomo, MD, PhD, surgeon, Ika Trisnawati, MD, MSc, internist, Nur R Ananda, MD, internist-pulmonologist, Paulus Wisnu, MD, pulmonologist 2020-10-27
Red cell antibody profile in Covid-19 Coronavirus disease 19 infection Direct antiglobulin test alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Seth GS Medical College India 2020-11-01 CTRI/2020/10/028567 Phase Not Applicable Not yet recruiting 1 200 Dr Swarupa Nikhil Bhagwat 2020-10-23
Study of the Safety of Prophylactic Vaccination With Second Generation E1/E2B/E3-Deleted Adenoviral-COVID-19 in Normal Healthy Volunteers Coronavirus disease 19 infection recombinant bivalent second-generation adenovirus (hAd5) vector-delivered SARS-CoV-2 S + N protein vaccine (oral, COVID-19), ImmunityBio alone, recombinant bivalent second-generation adenovirus (hAd5) vector-delivered SARS-CoV-2 S + N protein vaccine (subcutaneous, COVID-19), ImmunityBio alone COVID19 Spike glycoprotein modulator, COVID19 nucleoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) ImmunityBio Inc US 2020-10-19 2021-11-19 NCT04591717, QUILT-COVID-19-HAD5-VACCINE Phase 1b Clinical Recruiting 1 13 Months 35 Deborah Fridman, Lennie Sender 2020-10-27
A pivotal, phase III, randomized, double-blind, placebo-controlled trial of an interferon-beta (IFN-beta), SNG-001 treatment in the treatment of patients hospitalized with COVID-19 Coronavirus disease 19 infection inhaled interferon beta (lung disorders/influenza), Synairgen alone Interferon beta ligand PAREXEL International Synairgen plc Phase 3 Clinical Planned 0 900 2020-10-29
Outcomes of Elective Colorectal Cancer Surgery During COVID 19 Pandemic: Implications for Cancer Care Policy Colorectal tumor, Coronavirus disease 19 infection Colorectal resection alone Sher-i-Kashmir Institute of Medical Sciences India 2020-03-23 2020-10-22 73/2020 (SUPL 2), NCT04588909 Phase Not Applicable No longer recruiting 1 7 Months 100 ASIF MEHRAJ, Senior Resident, Nisar A Chowdri 2020-10-24
NET_COV: Assessment of Netosis During COVID-19, Under Treatment With Anakinra, an Interleukin-1 Receptor Antagonist Coronavirus disease 19 infection, Inflammatory disease anakinra alone Type I IL-1 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Groupe Hospitalier Paris Saint-Joseph France 2020-11-19 2021-06-30 NCT04594356, NET_COV, NET_COV Phase Not Applicable Not yet recruiting 1 7 Months 126 Gilles HAYEM, MD, Helene BEAUSSIER, PharmD, pHD, Sylvie CHOLLET MARTIN, MD 2020-10-27
This is a Phase I Study to Evaluate the Safety, Tolerability and Virology of CT-P59 in Patients With Mild Symptoms of Symptoms of Coronavirus Disease (COVID-19) Coronavirus disease 19 infection CT-P59 alone COVID19 Spike glycoprotein inhibitor, Moesin modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Celltrion Healthcare Co Ltd, Celltrion Inc South Korea 2020-09-04 2020-12-23 2020-003165-19, CT-P59 1.2, NCT04593641 Phase 1 Clinical No longer recruiting 1 3 Months 18 2020-10-23
Hydrogen-oxygen Gas Mixture Inhalation in Patients With Convalescent Coronavirus Disease 2019 (COVID-19) Coronavirus disease 19 infection, Viral pneumonia AMS-H-03 alone, hydrogen-oxygen gas alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Guangzhou Institute Of Respiratory Disease China 2020-10-31 2021-12-31 AMS-H-03-101, NCT04594460 Phase 2 Clinical Not yet recruiting 2 14 Months 198 Wei-jie Guan, PhD 2020-10-25
Impact of COVID-19 on Pediatric Dental Practice In Egypt Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Cairo University Egypt 2021-02-28 2022-01-31 NCT04592510, Y66CYYG6 Phase Not Applicable Not yet recruiting 1 11 Months 290 Adel El Bardissy, Fatma Essam El-Deen, Fatma Essam El-Deen Abdel Rahim, Shaimaa Sabry 2020-10-22
COVID-19 human challenge study Coronavirus disease 19 infection test vaccines alone Healthy volunteers accepted, Young Adults (18-44 yrs) Imperial College London, Open Orphan PLC UK Government, hVIVO plc UK Phase Not Applicable Planned 1 2020-10-22
MuCo: Mucosal Immunity Against SARS-CoV-2 Infection in COVID-19 Patients Coronavirus disease 19 infection biological sampling alone Radboud University Netherlands 2020-03-26 2020-05-13 2020-6342, MuCo, NCT04590352, NL73418.091.20 Phase Not Applicable Completed 1 1 Month 187 Dimitri Diavatopoulos, Dr 2020-10-23
EMO-COVID: Hemostatic Profile in Patients Affected by COVID-19 Coronavirus disease 19 infection, Thrombosis Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ospedale Papa Giovanni XXIII Italy 2020-03-25 2021-05-10 EMO-COVID, EMO-COVID-ASSTPG23, NCT04595110 Phase Not Applicable Recruiting 1 13 Months 400 ANNA FALANGA, Anna Falanga, MD, Laura Russo, BSc 2020-10-27
Propolis supplementation And Coronavirus Coronavirus disease 19 infection Propolis supplementation (Reyhan Naghsh Jahan Pharmaceutical Co) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Isfahan University of medical Sciences Iran 2020-08-22 IR.MUI.MED.REC.1399.337, IRCT20200802048267N1 Phase 2 Clinical Recruiting 1 80 Karim Sohrabi, Shaghayegh Haghjooy 2020-10-23
MRI-AIDED: MRI Changes of Acute Kidney Injury in COVID-19 Coronavirus disease 19 infection, Renal injury MRI scans alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospitals Of Derby and Burton NHS Foundation Trust NIHR Nottingham Biomedical Research Centre UK 2020-10-07 2023-09-30 287571, MRI-AIDED, NCT04594291, UHDB/2020/077 Phase Not Applicable Recruiting 1 35 Months 60 Maarten Taal, Professor, Nicholas Selby, Professor 2020-10-24
Defining the COVID-19 Immunity Denominator in the Mekong: a Cross-Sectional Seroprevalence Study of SARS-CoV-2 in Healthy Volunteers Coronavirus disease 19 infection ELISA alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) National Institute of Allergy and Infectious Diseases National Institutes of Health Clinical Center Cambodia 2020-11-10 2023-12-31 000083-I, 10000083, NCT04594395 Phase Not Applicable Recruiting 2 37 Months 2700 Jessica E Manning, M.D., Ly Sovann, Suon Seila, M.D. 2020-11-06
A propensity score matched, retrospective, cohort study to evaluate the effect of famotidine on the clinical outcomes of hospitalized patients with COVID-19 Coronavirus disease 19 infection famotidine alone, proton pump inhibitors alone Histamine H2 receptor antagonist Columbia University US Phase Not Applicable Status not specified 1 1620 2020-10-22
A late stage clinical trial of intranasal CodaVax-COVID for the prevention of Covid-19 Coronavirus disease 19 infection CodaVax-COVID alone Bharat Biotech International Ltd, Serum Institute of India Ltd Phase Not Applicable Planned 0 2020-10-22
COVIDWHELD: Improving Wellbeing and Health for Care Home Residents During COVID-19 Coronavirus disease 19 infection, Dementia COVID WHELD alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Exeter University Alzheimers Society, King's College London, London School of Economics and Political Science, University of East Anglia, University of Hull 2020-11-20 2022-01-01 20-21-10, COVIDWHELD, NCT04590469 Phase Not Applicable Not yet recruiting 0 13 Months 2880 Clive Ballard, MD, Clive G Ballard, MD, Dag Aarsland, MD 2020-10-24
MyeloidCovid: Myeloid Cells in Patients With COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia blood sampling alone, nasal brushing alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Assistance Publique Hopitaux de Paris INSERM India 2020-11-01 2023-11-01 2020-A02700-39, APHP201138, MyeloidCovid, NCT04590261 Phase Not Applicable Not yet recruiting 1 36 Months 120 Marie BENHAMMANI-Godard, Pierre-Régis Burgel, MD, PhD 2020-10-23
Study to Assess the Safety, Tolerability, and Pharmacokinetics of HFB-30132A Against COVID-19 in Healthy Adults Coronavirus disease 19 infection HFB-30132A alone Angiotensin converting enzyme 2 inhibitor, COVID19 Spike glycoprotein inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) HiFiBio US 2020-10-31 2021-07-31 HFB30132A-101, NCT04590430 Phase 1 Clinical Recruiting 1 9 Months 24 Francisco Adrian, Kari LaSalvia, Leela Vrishabhendra, MD 2020-10-28
COGCOV: The COGCOV Study in ICU Patients Cognitive disorder, Coronavirus disease 19 infection, Neurological disease Neurocognitive assessment alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ziekenhuis Oost-Limburg Belgium 2020-10-07 2021-02-28 COGCOV, COGCOV, NCT04593069 Phase Not Applicable Recruiting 1 4 Months 60 Dieter Mesotten, MD, Elly Vandermeulen, Elly Vandermeulen, PhD 2020-10-24
Evaluating an Online Wellness Intervention for Indian College Students Anxiety disorder, Coronavirus disease 19 infection, Depression Common Elements Toolbox alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Pennsylvania Ashoka University India 2020-10-19 2021-06-30 843879, NCT04592588 Phase Not Applicable Recruiting 1 8 Months 300 Akash Wasil, Tavni Malhotra 2020-11-02
A retrospective, cross-sectional study to evaluate the lopinavir/ritonavir and interferon combination therapy effects on shortening the duration of viral shedding in COVID-19 patients Coronavirus disease 19 infection interferon-gamma plus lopinavir + ritonavir HIV protease inhibitor Anhui Medical University China Phase Not Applicable Status not specified 1 181 2020-10-22
Testing Multiple Behavioral Science Strategies to Increase Flu-Shot Rates at a Large Retail Pharmacy Coronavirus disease 19 infection, Influenza virus infection flu shot text messages alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Pennsylvania US 2020-09-25 2020-12-31 843523-TRIAL B, NCT04590066 Phase Not Applicable No longer recruiting 1 3 Months 1200000 2020-10-23
ACROCOVID: Clinical and Mechanistic Study of Patients (With COVID-19 or Not) With a Recent Acrosyndrome Coronavirus disease 19 infection blood sampling alone, skin biopsy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris Cochin Institute France 2020-10-31 2020-12-31 ACROCOVID, APHP200884, NCT04590209, N° IDRCB 2020-A0181336 Phase Not Applicable Not yet recruiting 1 2 Months 25 Marie Benhammani-Godard, Nicolas Dupin, MD, PhD, Sélim Aractingi, MD, PhD 2020-10-24
PRONE-COVID: Prone Position to Improve Oxygenation in COVID-19 Patients Outside Critical Care Coronavirus disease 19 infection, Viral pneumonia Prone positioning alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cambridge University Hospitals NHS Foundation Trust UK 2020-09-03 2021-06-30 284061, NCT04589936, PRONE-COVID Phase Not Applicable Recruiting 1 9 Months 56 Akhilesh Jha, Andrew Ying, Celine Goh, Chen Zhang, Fangyue Chen, Iain Goodhart, Jonathan Fuld, Kate Fitzpatrick, Marie Fisk, Sam Mann 2020-10-23
Using Telemedicine to Optimize Teamwork and Infection Control of Critical and Highly-infectious Patients in an Emergency Department Coronavirus disease 19 infection telemedicine based communication alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Taiwan University Hospital Taiwan 2020-10-10 2021-10-30 202007114RINA, NCT04591873 Phase Not Applicable Not yet recruiting 1 12 Months 100 Chien-Hao Lin, MD 2020-10-24
An observational, longitudinal, prospective cohort study on the predictive factors for cardiac conduction abnormalities with hydroxychloroquine-containing combinations for COVID-19 Cardiovascular disease, Coronavirus disease 19 infection Variable regimens including azithromycin , hydroxychloroquine , lopinavir + ritonavir HIV protease inhibitor Hospital General Universitario De Elche Phase Not Applicable Status not specified 0 105 2020-10-22
A clinical trial of plasma-derived anti-SARS-CoV-2 IgG (COVID-19), Kedrion Biopharma/Kamada in the treatment of patients with COVID-19 infection Coronavirus disease 19 infection plasma-derived anti-SARS-CoV-2 IgG (COVID-19), Kedrion Biopharma/Kamada alone Kamada Ltd US Phase Not Applicable Planned 1 2020-10-22
ARCTIC: Aerosolized Inhaled Adenosine Treatment in Patients With Acute Respiratory Distress Syndrome (ARDS) Caused by COVID-19 Blood clotting disorder, Coronavirus disease 19 infection, Lung inflammation, Respiratory distress syndrome, Respiratory tract infection Aerogen nebulizer alone, adenosine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Florida US 2020-12-31 2022-12-31 ARCTIC, IRB202002127, NCT04588441, OCR39505 Phase 2 Clinical Not yet recruiting 1 24 Months 30 Amy Gunnett, Bruce Spiess 2020-10-23
MAOi-COV19: Impact of a Monoamine Oxidase Inhibitor on the Phenotype of Blood Mononucleated Cells in Patients With COVID-19 Coronavirus disease 19 infection phenelzine (Nardil) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-11-30 2021-11-30 2020-A02398-31, APHP200989, MAOi-COV19, NCT04590222 Phase Not Applicable Not yet recruiting 1 12 Months 80 Katia BOURDIC, Olivier LAMBOTTE, Olivier LAMBOTTE, Prof 2020-10-23
Expressive Writing for COVID-19 Resilience Acute stress disorder, Coronavirus disease 19 infection, Depression virtually-delivered expressive writing alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Duke University US 2020-05-26 2020-08-17 NCT04589104, PRO00105575 Phase Not Applicable Completed 1 2 Months 63 Oliver Glass, PhD 2020-10-21
Supporting Family Members With Severe Grief Reaction During the COVID-19 Pandemic Coronavirus disease 19 infection, Psychiatric disorder Bereavement Virtual Support alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ottawa Hospital Research Institute Canada 2020-11-01 2022-01-01 20200653-01H, NCT04588415 Phase Not Applicable Not yet recruiting 1 14 Months 200 Antoine Przybylak-Brouillard, Peter Lawlor 2020-10-21
COVID-19-DM: The Effect of COVID-19 on Diabetes Mellitus Coronavirus disease 19 infection, Diabetes mellitus Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Usak University, Turkey Turkey 2020-03-20 2020-11-01 COVID-19-DM, NCT04592055, UU-DM002 Phase Not Applicable Recruiting 1 7 Months 500 Cevdet Duran, Cevdet Duran, Prof 2020-10-23
ACTIV-1 IM: Immune Modulators for Treating COVID-19 Coronavirus disease 19 infection Variable regimens including abatacept , cenicriviroc , infliximab , remdesivir CCR2 chemokine antagonist, CCR5 chemokine antagonist, COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, Cytotoxic T-lymphocyte protein-4 stimulator, RNA polymerase modulator, T cell surface glycoprotein CD28 inhibitor, TNF alpha ligand inhibitor, TNF binding agent Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Duke University Biomedical Advanced Research and Development Authority (BARDA), Duke Clinical Research Institute, Fisher Bioservices, National Center For Advancing Translational Sciences, National Institutes of Health, Syneos Health Inc, Technical Resources International US 2020-10-15 2021-09-30 ACTIV-1 IM, NCT04593940, PRO00106301 Phase 3 Clinical Recruiting 4 11 Months 2160 Anne Lachiewicz, MD, Cameron Wolfe, Cameron Wolfe, MD, Carolina Aguiar, Daniel K Benjamin, MD, PhD, Jane O'Halloran, Jane O'Halloran, MD, Kimberly Lovell, Lori Hudson, PhD, Matthias Salathe, MD, Nayeem Choudhury, Theresa Jasion, MS, William G. Powderly 2020-11-04
A phase II clinical study to assess Nylexa in the treatment of patients with COVID-19 Coronavirus disease 19 infection mercaptamine (parenteral, COVID-19), NovaBiotics alone NovaBiotics Ltd Technology Strategy Board Phase 2 Clinical Planned 0 2020-10-21
A case-report study in the evaluation of FDG-PET/CT in a patient with COVID-19 Coronavirus disease 19 infection 18F-FDG alone, PET/CT alone, albumin alone, budesonide alone, hydroxychloroquine hydrochloride alone, interferon alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Zhengzhou University Phase Not Applicable Status not specified 0 1 2020-10-23
FaST-1: Furosemide as Supportive Therapy for COVID-19 Respiratory Failure Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia nebulized furosemide alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Queen's University University Health Network Toronto Canada 2020-10-19 2021-10-01 FAST-1, FaST-1, NCT04588792 Phase 2/Phase 3 Clinical Not yet recruiting 4 11 Months 640 Dave Maslove, MD, Gordon Boyd, MD, HT Wand, MD, John Muscedere, MD, Oleksa Rewa, MD, Osama Loubani, MD, Stephanie Sibley, MD, Tracy Boyd 2020-10-23
Mindfulness to Mitigate Psychological Threat and Improve Engagement and Learning in Introductory Physics Courses Coronavirus disease 19 infection, Psychiatric disorder Mindfulness Training alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Pittsburgh James S McDonnell Foundation, National Science Foundation US 2020-10-12 2022-12-31 NCT04589377, STUDY19050258 Phase Not Applicable Recruiting 1 26 Months 150 Brian Galla, PhD, Sara Jahanian, BS, Timothy Nokes-Malach, PhD 2020-10-21
Expressive Writing for COVID-19 Resilience for Parents Acute stress disorder, Coronavirus disease 19 infection, Depression Expressive writing alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Duke University US 2020-05-27 2020-08-02 NCT04589117, PRO00105586 Phase Not Applicable Completed 1 2 Months 11 Oliver Glass, PhD 2020-10-30
The Peer-Delivered "Mind. Body. Voice." Program for High School Women (Mbv) - Remote Coronavirus disease 19 infection, Eating disorder mind, body, voice program alone Healthy volunteers accepted, Female University of Colorado US 2020-10-09 2031-05-31 18-0007-03, NCT04591912 Phase Not Applicable Recruiting 1 127 Months 140 Bernadette Park, PhD, Gavin Bell, BA, Leah Pena Teeters, PhD, Leah Teeters, PhD, Sona A Dimidjian, PhD, Sona Dimidjian 2020-10-21
COCO-LATE: Late Clinical Events Associated With COVID-19 Infection Coronavirus disease 19 infection Biocollection alone, Follow-up visit alone, Questionnaire alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier de Tourcoing France, French Guiana 2020-10-31 2022-08-31 COCO-LATE, NCT04591613, RIPH_2020_09 Phase Not Applicable Not yet recruiting 17 22 Months 1000 Clara FLATEAU, Cédric JOSEPH, David CHIRIO, Delphine POITRENAUD, Dominique SALMON, Elisabeth BOTELHO-NEVERS, François GOEHRINGER, Louis BERNARD, Marie GOUSSEFF, Marie PICHENOT, Nicolas VIGNIER, Olivier ROBINEAU, Olivier ROBINEAU, MD PhD, Reda CHIKOUCHE, Solange TREHOUX, PhD, Sophie PANAGET, Vincent DUBEE, Xavier LESCURE 2020-10-23
Dulce Digital-COVID Aware (DD-CA) Discharge Texting Platform for US/Mexico Border Hispanics With Diabetes + COVID-19 Coronavirus disease 19 infection, Non-insulin dependent diabetes Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Scripps Whittier Diabetes Institute National Institute of Diabetes, Digestive and Kidney Diseases US 2020-11-01 2021-08-31 3R01DK112322-05S1, 3R01DK112322-05S1, NCT04591015 Phase 3 Clinical Not yet recruiting 1 10 Months 172 Athena Philis-Tsimikas, MD 2020-10-22
The Effect of Clear Masks in Improving Patient Relationships Coronavirus disease 19 infection Transparent mask alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of North Carolina US 2020-09-03 2020-12-31 20-2229, NCT04595695 Phase Not Applicable Recruiting 1 3 Months 100 Ian Kratzke, MD, Ian M Kratzke, MD 2020-10-23
COVID-19-PE: Pulmonary Embolism and COVID-19 Coronavirus disease 19 infection, Lung embolism Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Usak University, Turkey Turkey 2020-03-01 2020-12-01 COVID-19-PE, NCT04590378, UU-PE001 Phase Not Applicable Recruiting 1 9 Months 600 Barış Sevinç, M.D., Canan Akkus, M.D., Cevdet Duran, M.D., Cevdet Duran, Prof., Hakan Yilmaz, M.D. 2020-10-22
Safety and Efficacy of Hydroxychloroquine for the Treatment and Prevention of Coronavirus Disease 2019 (COVID-19) Caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Coronavirus disease 19 infection, Injury elderberry intake alone, Variable regimens including N-acetylcysteine , azithromycin , hydroxychloroquine , quercetin , vitamin C , vitamin D3 , zinc Healthy volunteers accepted International Brain Research Foundation Inc US 2020-11-30 2021-12-31 CTP-HCQ-COVID19, NCT04590274 Phase 1 Clinical Not yet recruiting 1 13 Months 5000 Philip DeFina, PhD 2020-10-24
COVID-RASi: The COVID-RASi Trial (COVID-19) Cardiovascular disease, Coronavirus disease 19 infection Angiotensin II Receptor Blockers alone, Angiotensin converting enzyme inhibitor alone, renin-angiotensin system inhibitors alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ottawa Heart Institute Research Corp Canada 2020-10-30 2022-08-31 COVID-RASi, CTO-3212, NCT04591210 Phase 3 Clinical Not yet recruiting 1 22 Months 1155 Ermina Moga, Peter Liu, MD 2020-10-22
COVID-19 and Lung Ultrasound Utility Coronavirus disease 19 infection Butterfly iQ system alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bridge to Health Medical and Dental USA Canada 2020-09-15 2021-09-30 0001, NCT04591158 Phase Not Applicable Recruiting 1 12 Months 100 William Cherniak, MD, MPH 2020-11-02
Remotely Delivered Programs Targeting COVID-19 Stress-Related Depression and Substance Use Acute stress disorder, Alcoholism, Anxiety disorder, Coronavirus disease 19 infection, Depression, Drug dependence CHAMindWell alone, Internet Cognitive Behavioral Therapy alone, Mindfulness Based Cognitive Therapy for Resilience During COVID-19 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Cambridge Health Alliance National Center for Complementary and Integrative Health, Pennsylvania State University US 2020-11-01 2022-11-01 3R33AT010125-03S1, CHA-IRB-1141/05/20, NCT04595084 Phase Not Applicable Not yet recruiting 1 24 Months 240 Carl Fulwiler, MD, Farah Samawi, Gabriella Conversano, Zev Schuman-Olivier, MD 2020-10-30
Maternal Telemental Health Interventions in Response to Covid-19*(CoronaVirus) Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression, Phobia Low-Intensity Psychosocial Interventions through Telemental health alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Hamad Medical Corp Qatar 2020-11-30 2022-02-28 MRC-05-087, NCT04594525 Phase Not Applicable Not yet recruiting 1 15 Months 58 2020-10-22
COVID-19 Burnout Study Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection Mindfulness Based Intervention alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Health Network Toronto 2020-11-01 2021-07-01 20-5678, NCT04594278 Phase Not Applicable Not yet recruiting 0 8 Months 100 2020-11-04
VGV: A 3-month Cycle of Virtual Guided Tours to Promote Health in Older Community Members in a Context of COVID-19 Induced Social Isolation: a Pilot Study Coronavirus disease 19 infection, Muscle weakness Museum virtual guided tours alone Healthy volunteers accepted, Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sir Mortimer B Davis Jewish General Hospital Canada 2021-01-04 2021-07-04 2021-2604, NCT04593433, VGV Phase Not Applicable Not yet recruiting 1 6 Months 40 Olivier Beauchet, MD 2020-10-27
GLS-1027 for the Prevention of Severe Pneumonitis Caused by SARS-CoV-2 Infection Coronavirus disease 19 infection, Viral pneumonia VGX-1027 (oral, type 1 diabetes/RA/psoriasis/colitis/uveitis), Inovio alone Nuclear factor kappa B inhibitor, p38 MAP kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) GeneOne Life Science Inc 2020-11-30 2021-11-30 GLS27-005, NCT04590547 Phase 2 Clinical Not yet recruiting 0 12 Months 132 Medical Monitor, Project Manager 2020-11-03
PRISM: COVID-19: Pediatric Research Immune Network on SARS-CoV-2 and MIS-C Coronavirus disease 19 infection, Inflammatory disease Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) National Institute of Allergy and Infectious Diseases Autoimmunity Centers of Excellence, Clinical Trials in Organ Transplantation US 2020-11-30 2022-11-30 DAIT PRISM-01, NCT04588363, NIAID CRMS ID#: 38772, PRISM Phase Not Applicable Not yet recruiting 22 24 Months 250 Charles E. Canter, MD, Ekemini Akan Ogbu, MBBS, MSc, Emily Wasserman, MD, MS, Hayley Gans, MD, James B. Schneider, MD, James D. Wilkinson, MD, MPH, John F. Bonsack, MD, Joseph Rossano, MD,MS,FAAP,FACC, Karen P. Acker, MD, Lara A. Danziger-Isakov, MD, MPH, Leigh M. Howard, MD, MPH, Lisa F. Imundo, MD, Maria T. Thanjan, MD, Marian G. Michaels,, MD, MPH, Moshe Arditi, MD, Nadine F. Choueiter, MD, Natasha B Halasa, MD, MPH, Natasha Ruth, MD, MS, Octavio Ramilo, MD, Paul F. Kantor, MBBCh,MSc,FRCPC, Pramod Narula, MD, Rakesh Singh, MD, Rana Chakraborty, MD, DPhil, Steven A. Webber, MBChB, MRCP, William T. Mahle, MD 2020-11-04
This is a Phase I Clinical Trial to Evaluate the Safety, Pharmacokinetics, and Immunogenicity of ADM-03820, a Monoclonal Antibody Cocktail Being Tested for the Treatment and Prevention of COVID-19 Coronavirus disease 19 infection SARS-CoV-2 monoclonal antibodies (COVID-19), Ology/ VUMC alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Ology Bioservices Inc US 2020-11-16 2021-08-30 ADM03820-001, NCT04592549 Phase 1 Clinical Not yet recruiting 2 9 Months 40 Angie Kimbler, Cassandra C Key, MD, Jonathan P Wilson, DO 2020-10-22
Study to Evaluate the Safety, Tolerability and Immunogenicity of an RNA Vaccine Candidate Against COVID-19 in Healthy Japanese Adults Coronavirus disease 19 infection BNT-162b2 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Japanese Ancestry BioNTech SE Pfizer Inc Japan 2020-10-20 2021-11-30 C4591005, NCT04588480 Phase 1/Phase 2 Clinical Recruiting 2 13 Months 160 Pfizer CT.gov Call Center 2020-10-22
Measurement of IL-6 and Secondary Inflammatory Markers Before and After Therapeutic Plasma Exchange (TPE) in Hospitalized Patients Acute lung injury, Coronavirus disease 19 infection, Respiratory distress syndrome therapeutic plasma exchange alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Larkin Community Hospital US 2020-09-11 2021-08-30 LCH-1-092020, NCT04592705 Phase 1 Clinical Recruiting 1 11 Months 10 Michael Talalaev, D.O. 2020-10-29
To Evaluate the Safety, Tolerability and Pharmacokinetic Properties of DWRX-2003 Coronavirus disease 19 infection repositioned niclosamide (refractory lung disease/COVID-19), Daewoong Pharmaceutical/Institut Pasteur Korea alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Daewoong Pharmaceutical Co Ltd Novotech (Australia) Pty Ltd Australia 2020-10-19 2021-06-30 DW_DWJ1516101_AUSTRALIA, NCT04592835 Phase 1 Clinical Not yet recruiting 1 8 Months 24 2020-11-04
Effectiveness of Ivermectin and Doxycycline on COVID-19 Patients Coronavirus disease 19 infection Mechanical ventilation alone, Oxygen therapy/ C-Pap alone, Variable regimens including Vitamin C , Vitamin D3 , Zinc , acetaminophen , azithromycin , dexamethasone , doxycycline (Doxycin) , ivermectin , methylprednisolone Chloride channel modulator Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Alkarkh Health Directorate-Baghdad Iraq 2020-07-01 2020-10-14 IVM-DOX, NCT04591600 Phase 1/Phase 2 Clinical Completed 1 3 Months 140 Ahmed Sahib Abdulamir 2020-10-22
Study of Multiple Candidate Agents for the Treatment of COVID-19 in Hospitalized Patients Coronavirus disease 19 infection Standard of care alone, apremilast alone PDE 4 inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Amgen Inc 2020-10-26 2021-07-13 2020-002594-10, COV-01, NCT04590586 Phase 3 Clinical Not yet recruiting 0 8 Months 700 Amgen Call Center 2020-10-21
Seroprevalence of SARS CoV-2 infections/Covid-19 in blood donors and patients of the University Hospitals in Leipzig Coronavirus disease 19 infection Institut für Virologie, Universitätsklinikum Leipzig Germany 2020-06-20 147/20-ek, DRKS00023364 Phase Not Applicable Recruiting 1 2000 Christian Jassoy 2020-10-21
Evaluation the effect of virtual pulmonary rehabilitaion on covid 19 patients Coronavirus disease 19 infection Breathing exercise alone, Virtual pulmonary rehabilitation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Shiraz University of Medical Sciences Iran 2020-10-20 IR.SUMS.MED.REC.1399.364, IRCT20200930048892N1 Phase Not Applicable Recruiting 3 70 Abbas Rezaeian zade, Fariba Erfani, Parnian Nikmanesh, Seyed Mohammad Kazem Tadayyon, Seyed Rouhollah Mousavi 2020-10-21
Abdominal CT scan findings in patients with COVID-19 Coronavirus disease 19 infection abdominal CT scan alone Philippine General Hospital Philippines 2020-08-15 2020-09-18 PHRR201015-003026 PHRR201015-003026 Phase Not Applicable Completed 1 1 Month Gerard Eastdon Truadio D. Ochoco, MD 2020-10-21
SPARCOL: SuPAR in Adult Patients With COVID-19 Coronavirus disease 19 infection ELISA assay alone, suPARnostic kit (ViroGates) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Thessaly Greece 2020-10-11 2020-12-10 NCT04590794, SPARCOL, UTHDA-AC03 Phase Not Applicable Recruiting 1 2 Months 500 Athanasios Chalkias, PhD, Barbara Boutsis, Mrs, Eleni Laou, PhD 2020-10-24
CoV-Early: Early Convalescent Plasma Therapy for High-risk Patients With COVID-19 in Primary Care Coronavirus disease 19 infection convalescent plasma alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Erasmus University Medical Center Rotterdam Leiden University Medical Center, Sanquin Plasma Products B.V., The Netherlands Organisation for Health Research and Development Netherlands 2020-10-12 2023-11-01 CoV-Early, NCT04589949, NL74972.078.20 Phase 3 Clinical Recruiting 11 36 Months 690 Arvind Gharbharan, MD, Bart Rijnders, MD, PhD, Carlijn Jordans, MD, Casper Rokx, MD, PhD, D. Postma, MD, PhD, E. Jong, MD, PhD, Elana van Leeuwen, MD, PhD, Faiz Karim, MD, PhD, I Ludwig, MD, JJ Zwaginga, MD/PhD, L. Kampschreur, MD, PhD, R.W. van Etten, MD, PhD, Robert-Jan Hassing, MD, PhD, Robin Soetekouw, MD 2020-10-21
Development of a risk prediction model for people with diabetes and COVID-19 in Scotland Coronavirus disease 19 infection, Diabetes mellitus risk prediction model alone Health Protection Scotland Public Health Scotland UK 2020-04-06 2020-07-31 ISRCTN45562523, PBPP REF. 1617- 0147 Phase Not Applicable Completed 1 3 Months 5782649 Prof Colhoun 2020-11-02
COVID-19-DM2: The Effect of Diabetes Mellitus on the Prognosis of Patients With COVID-19 Coronavirus disease 19 infection, Diabetes mellitus Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Usak University, Turkey Turkey 2020-03-20 2020-11-01 COVID-19-DM2, NCT04591704, UU-DM003 Phase Not Applicable Recruiting 1 7 Months 2000 Cevdet Duran 2020-10-21
Evaluation of the effect of Tofacitinib in COVID-19 patients Coronavirus disease 19 infection Rhofanib (Alvand Nanotechnology Company) alone Iran University of Medical Sciences Iran 2020-08-21 IR.IUMS.FMD.REC.1399.329, IRCT20200531047619N1 Phase 3 Clinical Recruiting 1 10 Seyed Abbas Motavalian, Simin Almasi 2020-10-21
ICE-COVID: Iota-carrageenan Nasal Spray COVID-19 Prophylaxis for Healthcare Professionals Coronavirus disease 19 infection Coldamaris plus iota-carrageenan (intranasal, H1N1 influenza), Marinomed Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Swansea University, Wales Abertawe Bro Morgannwg University Health Board, Cardiff University, Marinomed Biotechnologie GmbH, Walgreens Boots Alliance Inc UK 2020-12-20 2021-12-01 283187, ICE-COVID, NCT04590365 Phase 3 Clinical Not yet recruiting 1 11 Months 480 Iain S Whitaker, PhD FRCS, Zita M Jessop, MBBChir PhD 2020-10-22
FLAVOCOV Distributed Clinical Trial- COVID-19 Coronavirus disease 19 infection flavonoids alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Thermosystems EA Kenya Medical Research Institute Kenya 2020-11-01 2021-01-31 PACTR202010537777617 Phase Not Applicable Not yet recruiting 1 3 Months 200 Leah Kigondu, Rick Sheridan, Willie Nyambati 2020-11-05
COREADOM: French Cohort of COVID-19 Patients With Post-intensive Care Syndrome Coronavirus disease 19 infection Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-10-15 2021-09-15 APHP200812, COREADOM, NCT04590170 Phase Not Applicable Not yet recruiting 1 11 Months 50 Camille : Camille, MD, Camille Camille, MD, Marie Benhammani-Godard, Marie-Martine Marie-Martine, MD, PhD 2020-10-21
VISION-Acute: The VISION-Acute Study Coronavirus disease 19 infection, Hypertension, Hypotension, Hypoxia, Respiratory disease Lifelight data collect app (Xim Ltd) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Xim Ltd Portsmouth Hospitals UK 2020-10-31 2021-01-31 NCT04589923, PHT/2020/50, VISION-Acute Phase Not Applicable Not yet recruiting 1 3 Months 200 Laura Wiffen 2020-10-20
Allocetra-OTS in COVID-19, Phase II Coronavirus disease 19 infection, Multiple organ failure, Respiratory disease, Respiratory failure, Septic shock standard of care therapy alone, Allocetra plus Ringer's lactate solution Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hadassah Medical Organization Barzilai medical center, Tel Aviv Sourasky Medical Center Israel 2020-05-07 2021-03-31 DM004, NCT04590053 Phase 2 Clinical Recruiting 3 10 Months 24 Dror Mevorach, MD, Peter V van Heerden, MD, Ronen Ben-Ami, Prof., Shlomo L Maayan, Prof. 2020-10-29
Levamizole in treatment of COVID-19 Coronavirus disease 19 infection levamisole alone, standard therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Isfahan University of medical Sciences Iran 2020-10-22 IR.MUI.MED.REC.1399.246, IRCT20181208041886N1 Phase 2 Clinical Recruiting 1 60 Dr. Shaghayegh Haghjoo, Morteza Pourahmad 2020-10-22
COVID-19 biomarker: Identification of biomarkers for prognosis of morbidity and mortality of SARS-CoV-2 (COVID-19) patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Munster Germany 2020-04-09 AZ 2020-210-f-S, COVID-19 biomarker, DRKS00023322 Phase Not Applicable Recruiting 1 100 Phil-Robin Tepasse 2020-10-21
A Clinical Trial of a Plasmid DNA Vaccine for COVID-19 (Covigenix VAX-001) in Adults Coronavirus disease 19 infection SARS-CoV-2 DNA vaccine (COVID-19), Entos/ Epivax alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Entos Pharmaceuticals Inc Canadian Center for Vaccinology, Canadian Institutes of Health Research, National Research Council of Canada Canada 2020-11-30 2021-06-30 ENTVAX01-101, NCT04591184 Phase 1/Phase 2 Clinical Not yet recruiting 1 7 Months 72 Gregory Reid, M.Sc, MBA, Sally Jones, Scott A. Halperin, M.D. 2020-10-27
Anhydrous Enol-Oxaloacetate (AEO) on Improving Fatigue in Post-COVID-19 Survivors Coronavirus disease 19 infection, Fatigue anhydrous enol-oxaloacetate (Terra Biological LLC) alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Terra Biological LLC US 2020-10-15 2021-06-15 NCT04592354, TB-AEO-2020 POST COVID FATIGUE Phase Not Applicable Recruiting 1 8 Months 40 Alan B Cash, MS, Lisa Tully, Ph.D. 2020-10-21
A prospective study to evaluate the accuracy of the Cue COVID-19 Test in patients Coronavirus disease 19 infection Cue COVID-19 Test alone Mayo Clinic Foundation Phase Not Applicable Status not specified 0 2020-10-20
A phase I/II clinical study to assess MRT-5500 in the treatment of subjects with SARS-CoV-2 infection Coronavirus disease 19 infection SARS-CoV-2 mRNA vaccine (COVID-19), Sanofi Pasteur/ Translate Bio alone Sanofi SA 2020-12-31 Phase 1/Phase 2 Clinical Planned 0 2020-11-03
A clinical trial to evaluate the efficacy of erdosteine in the treatment of hospitalized patients with COVID-19 infection with severe respiratory failure Coronavirus disease 19 infection, Respiratory failure erdosteine alone Elastase inhibitor Recipharm AB Italy Phase 2 Clinical Status not specified 1 20 2020-10-20
AERATOR: Studying aerosol emission of the COVID-19 virus in healthcare settings Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) North Bristol NHS Trust National Institute for Health Research (NIHR), United Kingdom Research & Innovation UK 2020-09-19 2021-09-19 3.4, IRAS 288784, CPMS 47097, AERATOR, ISRCTN21447815 Phase Not Applicable Recruiting 2 12 Months 600 Dr Fergus Hamilton 2020-10-22
Experience In Managing Special Groups Of Person Under Surveillance In Kelantan Coronavirus disease 19 infection Ministry of Health, Malaysia Malaysia 2020-10-18 2021-10-05 56079, NMRR-20-2238-56079 Phase Not Applicable Status not specified 1 11 Months Dr Farah Munirah Binti Mior Mazlan, dr NIK AIDA BT NIK ADIB 2020-10-20
Treatment of Covid-19 Using Infrared and/or Vitamin C Coronavirus disease 19 infection Infrared sauna therapy alone, vitamin C alone Healthy volunteers accepted GAAD Medical Research Institute Inc Canada 2020-10-30 2021-07-10 GAADMRI, NCT04584437 Phase Not Applicable Not yet recruiting 1 8 Months 400 Dr. Kwasi D Donyina, PhD, Yaa A Donyina, MDE 2020-10-27
A multicenter, clinical trial to validate the effectiveness of the Monocyte Distribution Width (MDW) hematology biomarker in the rapid detection of Multisystem Inflammatory Syndrome in Children (MIS-C) following SARS-CoV-2 infection Coronavirus disease 19 infection, Inflammatory disease Beckman Coulter Diagnostics Biomedical Advanced Research and Development Authority (BARDA), Johns Hopkins University School of Medicine, Massachusetts General Hospital, University of Florida US Phase Not Applicable Planned 3 Lael Yonker, M.D 2020-10-20
Secondary attack rate of COVID-19 and risk factors for transmission Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sri Ramachandra Institute of Higher Education and Research India 2020-10-16 CTRI/2020/10/028439 Phase Not Applicable Not yet recruiting 1 100 Manisha Arthur 2020-10-20
Efficacy of daclatasvir + sofosbuvir in patients with severe acute respiratory syndrome coronavirus (SARS-COVID-19) Coronavirus disease 19 infection, Viral pneumonia daclatasvir/sofosbuvir (Danesh Pharmaceutical Development Company) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ahvaz University of Medical Sciences Ahvaz Jundishapur University of Medical Sciences Iran 2020-06-25 IR.AJUMS.REC.1399.300, IRCT20200816048422N1 Phase 1/Phase 2 Clinical No longer recruiting 1 70 Dr Fatemeh Ahmadi, Dr. Fatemeh Ahmadi, Dr. Mohammad Badawi, Dr. Zahra Fakhraei 2020-10-20
PRECISION: An observational PRECISION study , to examine the immune responses to COVID-19 in healthy volunteers who have recovered from COVID-19 or were asymptomatic Coronavirus disease 19 infection Columbia University, Tonix Pharmaceuticals Holding Corp US PRECISION, TNX-C002 Phase Not Applicable Recruiting 1 Dr. Ilya Trakht, Dr. Sergei Rudchenko, Ph.D 2020-10-19
A clinical study to assess COVID-19 vaccine for the potential treatment of COVID-19 Coronavirus disease 19 infection coronavirus vaccine (whole-virion, inactivated/purified), FGBNU FNTSIRIP im MP Chumakova RAN alone M P Chumakov Institute of Poliomyelitis and Virus Encephalitides Russian Federation 2020-10-19 Phase Not Applicable Planned 1 2020-10-31
Effect of Ayurvedic Treatment Regimen in COVID-19 Patients Coronavirus disease 19 infection Variable regimens including Bilwadi Yog , Kantakaryavaleha , Shadangodak Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ministry of Ayush India 2020-11-02 CTRI/2020/10/028437 Phase 3 Clinical Not yet recruiting 3 380 Dr Leena Badgujar, Dr Milind B Nikumbh, Dr Shoeb Shaikh 2020-10-21
A trial to evaluate FX-06 in severe cases of COVID-19 Coronavirus disease 19 infection FX-06 alone Cadherin-5 modulator, Factor Ia modulator F4 Pharma GmbH Europe Phase Not Applicable Planned 0 2020-10-19
Perspective of cancer patient in COVID-19 pandemic Cancer, Coronavirus disease 19 infection chemotherapy alone, radiotherapy alone, systemic therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Indira Gandhi Medical College India 2020-12-01 CTRI/2020/10/028438 Phase 3 Clinical Not yet recruiting 1 1000 Shabnum Thakur 2020-10-21
A trial to evaluate stem cell therapy as a treatment for acute symptoms of COVID-19 Coronavirus disease 19 infection stem cell therapy alone BioXcellerator US Phase Not Applicable Not yet recruiting 1 2020-10-19
This study is designed to look at certain blood parameters like biomarkers for predicting the outcome of COVID patients Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) St Johns Medical College India 2020-10-25 CTRI/2020/10/028436 Phase Not Applicable Not yet recruiting 1 130 Dr Amarja Havaldar 2020-10-20
A phase III trial to evaluate post-exposure prophylaxis and pre-emptive treatment of AZD-7442 in covid-19 patients Coronavirus disease 19 infection AZD-7442 alone COVID19 Spike glycoprotein inhibitor AstraZeneca plc Biomedical Advanced Research and Development Authority (BARDA) US Phase 3 Clinical Planned 1 1100 2020-10-23
A phase III trial to evaluate the safety and efficacy of AZD7442 to prevention of COVID-19 Coronavirus disease 19 infection AZD-7442 alone COVID19 Spike glycoprotein inhibitor AstraZeneca plc Biomedical Advanced Research and Development Authority (BARDA) US Phase 3 Clinical Planned 1 5000 2020-10-23
Mental health of COVID 19 patients during outbreak Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression RTPCR test  alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) All India Institute of Ayurveda India 2020-10-16 CTRI/2020/10/028432 Phase Not Applicable Not yet recruiting 1 400 Dr Shivakumar Harti 2020-10-20
CoMMinS: COVID-19 testing and infection control in schools Coronavirus disease 19 infection RNA PCR test alone, Saliva-based antibody test alone, Viral RNA genome sequencing alone University of Bristol Medical Research Council UK 2020-09-01 2021-08-31 CoMMinS, IRAS 290071, ISRCTN82901740 Phase Not Applicable Not yet recruiting 1 12 Months 5000 Mrs Downing, Prof Caroline Relton 2020-11-04
A phase III clinical trial of Sputnik V for the potential prevention of COVID-19 infection Coronavirus disease 19 infection Sputnik V alone COVID19 Spike glycoprotein modulator Gamalei Institute of Epidemiology and Microbiology Philippines Phase 3 Clinical Recruiting 1 2020-10-19
A phase III clinical trial of Sputnik V for the potential prevention of COVID-19 infection Coronavirus disease 19 infection Sputnik V alone COVID19 Spike glycoprotein modulator Gamalei Institute of Epidemiology and Microbiology Saudi Arabia, United Arab Emirates 2020-10-13 Phase 3 Clinical Recruiting 2 2020-10-19
A clinical trial of ASLAN-003 for the treatment of Covid-19 and other viral infections Coronavirus disease 19 infection, Viral infection ASLAN-003 alone Dihydroorotate dehydrogenase inhibitor, p53 tumor suppressor protein stimulator ASLAN Pharmaceuticals Pte Ltd Phase Not Applicable Planned 0 2020-10-26
Cohort survey of healthcare workers with COVID-19 infection Coronavirus disease 19 infection Healthy volunteers accepted Chiba University Graduate School of Medicine Japan 2020-05-19 2020-06-11 UMIN000042142 Phase Not Applicable Completed 1 103 Taka-aki Nakada, Takeo Kurita 2020-10-21
An observational, case report to determine the diagnosis and management of upper gastrointestinal bleeding caused by SARS-CoV-2 infection during hospitalization Coronavirus disease 19 infection, Gastrointestinal bleeding Yunnan white drugs alone, gastroscopy alone, Variable regimens including aluminum phosphate , esomeprazole , octreotide acetate , thrombin Factor IIa agonist, H+ K+ ATPase inhibitor, Somatostatin receptor agonist Sun Yat-Sen University Phase Not Applicable Status not specified 0 1 2020-10-21
Evaluation of Respiratory profile and radiological changes in patients after recovery from COVID-19 Coronavirus disease 19 infection nintedanib alone, pirfenidone alone CSF-1 antagonist, FGF receptor antagonist, FGF1 receptor antagonist, FGF2 receptor antagonist, FGF3 receptor antagonist, Flt3 tyrosine kinase inhibitor, Lck tyrosine kinase inhibitor, Lyn tyrosine kinase inhibitor, PDGF receptor alpha antagonist, PDGF receptor antagonist, PDGF receptor beta antagonist, Src tyrosine kinase inhibitor, TGF beta receptor antagonist, VEGF receptor antagonist, VEGF-1 receptor antagonist, VEGF-2 receptor antagonist, VEGF-3 receptor antagonist, p38 MAP kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences India 2020-10-22 CTRI/2020/10/028372 Phase 4 Clinical Not yet recruiting 1 500 Anant Mohan 2020-10-20
Experiences among nurses caring patients with COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Manipal Academy of Higher Education India 2020-10-30 CTRI/2020/10/028373 Phase Not Applicable Not yet recruiting 1 30 Dr Leena Sequira, SHALINI G NAYAK 2020-10-20
A Clinical Study to Evaluate the Safety and Efficacy of CoviTone in Mild to Moderate COVID patients Coronavirus disease 19 infection CoviTone alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Arber Biosciences Pte. Ltd India 2020-10-22 CTRI/2020/10/028376 Phase 2 Clinical Not yet recruiting 1 80 Dr M E Mohan, Jestin V Thomas 2020-11-05
KluT: COVID-19 Cluster in Temerloh: Is it related to tabligh? Coronavirus disease 19 infection Temerloh District Health Office 2020-10-13 2021-02-08 55897, KluT, NMRR-20-2208-55897 Phase Not Applicable Recruiting 0 3 Months Dr. Safaridah binti Anuar 2020-11-06
PVAS COVID-19: COVID-19: Public Awareness, Perception and Impact on Pharmacy Value Added Services (PVAS) in Kedah, Malaysia Coronavirus disease 19 infection Hospital Jitra Malaysia 2020-10-15 2021-06-30 55892, NMRR-20-2195-55892, PVAS COVID-19 Phase Not Applicable Not yet recruiting 1 8 Months Mrs Nurliana Binti Abdul Latif, norazila bt abdul ghani 2020-11-05
Effect of remdesivir in COVID-19 Coronavirus disease 19 infection remdesivir alone COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ahvaz University of Medical Sciences Iran 2020-09-27 IR.AJUMS.REC.1399.407, IRCT20200404046937N5 Phase 2/Phase 3 Clinical No longer recruiting 2 50 Dr Fatemeh Ahmadi, Mehdi Ahmadi Moghadam, Mehran Varnaseri, Mehran Varnasseri, Roohangiz Nashibi 2020-11-02
Cope-Corona: Identifying and strengthening personal resources to cope with the corona pandemic Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression, Psychiatric disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tongji Hospital China 2020-08-01 2023-07-31 ChiCTR2000038929, Cope-Corona Phase Not Applicable Not yet recruiting 1 36 Months 600 Heng Wu, Zheng Lu 2020-10-19
COVADIS study: COVID-19 Epidemic in West Africa (WA): infection dynamics and diagnostic approaches Coronavirus disease 19 infection COVID test kit alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Medical Research Council Unit, The Gambia European and Developing Countries Clinical Trials Partnership Gambia 2020-10-12 COVADIS study, PACTR202010472402152 Phase Not Applicable No longer recruiting 1 1100 Annette Erhart, Bakary Conteh, Vivat Thomas Njie 2020-10-19
ANTICOV IMMUNO: The impact of COVID-19 treatment on the type, strength and duration of antibody and cellular immune responses in SARS-CoV-2 patients in sub-Saharan Africa Ancillary Study of the ANTICOV Study: An open-label, multicentre, randomised, adaptive platform trial of the safety and efficacy of several therapies, including antiviral therapies, versus control in mild / moderate cases of COVID-19 Coronavirus disease 19 infection hydroxychloroquine alone, lopinavir + ritonavir alone HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bernhard-Nocht-Institute for Tropical Medicine, Drugs for Neglected Diseases Initiative, Ifakara Health Institute, Institute of Tropical Medicine Egypt 2020-09-21 ANTICOV IMMUNO, PACTR202010781639956 Phase Not Applicable Recruiting 1 1000 Gemma Moncunill, James Arkinstall, Nathalie StrubWourgaft 2020-10-20
A clinical trial to evaluate the efficacy of polyvalent highdosage intravenous immunoglobulin to stabilize or improve the health of COVID-19 patients Coronavirus disease 19 infection polyvalent high-dosage intravenous immunoglobulin alone Grifols SA Spain Phase Not Applicable Planned 1 2020-10-19
KoCo19-CED-1: Clinical care situation, health problems and psychosocial burdens during the COVID-19-pandemic in patients with chronic inflammatory bowel disease (IBD) - Part 1: Baseline survey and seroprevalence of SARS-CoV-2 antibodies compared to Munich population cohort (KoCo19) Coronavirus disease 19 infection, Inflammatory bowel disease blood test alone Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Klinikum der Universitat Muenchen Germany 2020-07-04 20-523, DRKS00021698, DRKS00022155, KoCo19-CED-1 Phase Not Applicable Recruiting 2 400 Elisabeth Klucker, Leandra Koletzko, Sibylle Koletzko, Simone Breiteneicher, Tobias Schwerd 2020-10-20
PRASACT: Clinical study to evaluate the effect of Ayurveda intervention as a prophylaxis for COVID-19 in Healthcare workers Coronavirus disease 19 infection Variable regimens including Amritotaram Kashayam Prakshepa , Chywanaprasha , Dasamoola Katutrayam Kashayam , Dhanvantaram Gutika , GuduchyAdi Kashayam Prakshepa , Haridrakhandam , Indukantam Kashayam , Nayopayam KS Prakshepa , Sudarshana Ghana Vati , Vasaristam+Kanakasavam , VidAryAdi KS Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ministry of Ayush India 2020-10-30 CTRI/2020/10/028424, PRASACT Phase 3 Clinical Not yet recruiting 1 200 Dr Zankhana Buch 2020-10-19
A clinical study to see the effects and safety of PNB-001 in patients with moderate COVID-19 infection Coronavirus disease 19 infection PNB-001 alone, Standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Byramjee Jeejeebhoy Govt Medical College and Sassoon General Hospitals India 2020-10-28 BCR-PNB-001, CT/ND/95/2020, CTRI/2020/10/028423 Phase 2 Clinical Not yet recruiting 1 40 Dr Neeta Nargundkar, Dr Pradnya Bhalerao 2020-10-20
Effect of COVID-19 on lymphocyte and eosinophil count Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences Patna India 2020-10-24 CTRI/2020/10/028422 Phase Not Applicable Not yet recruiting 1 150 DR AMARJEET KUMAR 2020-10-21
The effect of synbiotic on inflammatory markers and clinical manifestations in patients with COVID-19 Coronavirus disease 19 infection Lactocar synbiotic alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Isfahan University of medical Sciences Iran 2020-10-22 IR.MUI.MED.REC.1399.204, IRCT20200923048815N1 Phase 2/Phase 3 Clinical Recruiting 1 80 Majid Aghadavood Marnani, Masha Khodadoostan Shahraki, Shaghayegh Haghjoy Javanmard 2020-10-22
SaNPS: Stress and neuropsychiatric symptoms/disorders (ie, functional brain diseases): COVID-19 as a source of stress Acute stress disorder, Coronavirus disease 19 infection group wellbeing therapy group wellbeing therapy alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Xuanwu Hospital Of Capital Medical University China 2020-01-04 2021-01-04 ChiCTR2000039079, SaNPS Phase Not Applicable Recruiting 1 12 Months 400 Hongxing Wang 2020-10-20
PAP SURVEY: A Survey of Psychological Distress and Its Associated Factors Among Health Service Providers Amidst the Covid-19 Pandemic in Malaysia Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression Healthy volunteers accepted Selayang Hospital Malaysia 2020-11-10 2020-12-16 56529, NMRR-20-2235-56529, PAP SURVEY Phase Not Applicable Status not specified 1 1 Month Dr Muhammad Haniff Bin Abdullah 2020-10-21
Persuasion in Medicine: Experimental Evidence on Sender and Signal Effects Coronavirus disease 19 infection Video about safety and effectiveness alone, direct messaging on COVID-19 vaccine safety and efficacy alone Healthy volunteers accepted, Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Harvard University Massachusetts Institute of Technology, Stanford University US 2019-12-20 2021-02-15 IRB19-1424, NCT04160975 Phase Not Applicable Recruiting 1 13 Months 3350 2020-10-19
Kap of New Normal among HCW's in Hospital Kuala Lumpur and Hospital Sungai Buloh Regarding Covid-19 Coronavirus disease 19 infection University of Malaya Malaysia 2020-11-01 2021-10-31 NMRR-20-2224-56820 Phase Not Applicable Status not specified 2 12 Months Dr Sri Viknarajan A/L Puvendran 2020-10-16
COVID19-MSK INJECTION Coronavirus disease 19 infection, Rheumatoid arthritis HOSPITAL QUEEN ELIZABETH II Malaysia 2020-10-31 2021-08-02 NMRR-20-2221-56202 Phase Not Applicable Status not specified 1 9 Months MOHAMAD AZWAN BIN AZIZ 2020-10-20
EDWH COVID-19 Coronavirus disease 19 infection Melaka Hospital Malaysia 2020-10-25 2020-12-31 NMRR-16-2910-29170 Phase Not Applicable Status not specified 5 2 Months Madam NOORHALIZA BT ALI 2020-10-20
A study to assess safety and efficacy of natural killer cells in the treatment of covid-19 Coronavirus disease 19 infection K-NK-ID101 alone Abigail Wexner Research Institute, Kiadis Pharma BV Phase Not Applicable Planned 0 2020-10-16
The COVID PROFILE study Coronavirus disease 19 infection Walter and Eliza Hall Institute of Medical Research Royal Melbourne Hospital, The Peter Doherty Institute for Infection and Immunity, University of Melbourne Phase Not Applicable Status not specified 0 300 Dr Vanessa Bryant, Professor Ivo Mueller 2020-10-16
NCoV-Radi: NCoV-Radi Coronavirus disease 19 infection chest radiography alone, computed tomography imaging alone The University of Hong Kong Hong Kong 2020-02-10 2021-01-31 HKUCTR-2850, NCoV-Radi, UW 20-115, v1 Phase Not Applicable Recruiting 1 11 Months 50 Dr. Ming-Yen Ng, HKUCTR Administrator 2020-10-19
ICARD: The impact of COVID-19 pandemic-related activity restriction on the outcomes of chronic obstructive lung disease Chronic obstructive pulmonary disease, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Nagoya University Nagoya University Graduate School of Medicine Japan 2020-09-01 2023-03-31 ICARD, UMIN000042106 Phase Not Applicable Recruiting 1 31 Months 150 Akira Ando, Naozumi Hashimoto 2020-10-20
A Phase I, Open-Label, Parallel-Group, Single-Dose Study to Evaluate the Pharmacokinetics of Remdesivir and Metabolites in Participants with Normal Renal Function and Renal Impairment Coronavirus disease 19 infection remdesivir alone COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Gilead Sciences Inc Puerto Rico, US, Australia, Germany, New Zealand 2020-11-02 2022-03-01 ACTRN12620001048976p Phase 1 Clinical Not yet recruiting 5 16 Months 80 Dr Christian Schwabe 2020-11-06
REMOTE CONTROL: Home-based blood pressure monitoring of Hypertensive Diseases in Pregnancy - A randomized, controlled trial Coronavirus disease 19 infection, Hypertension, Pre-eclampsia Home-based blood pressure monitoring -app alone, automated BP machine alone, education and training alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Campbelltown Hospital, Liverpool Hospital Heart Research Institute Ltd Australia 2021-01-01 ACTRN12620001049965p, REMOTE CONTROL Phase Not Applicable Not yet recruiting 2 300 Dr Theepika Rajkumar 2020-11-06
Extended SIR model Coronavirus disease 19 infection Clinical Research Centre 2020-10-14 2021-10-13 56878, NMRR-20-2217-56878, model01 Phase Not Applicable Status not specified 0 12 Months Pharmacist Law Kian Boon 2020-10-19
SERVQUAL Model in Hospital Coronavirus disease 19 infection health management alone Universiti Kebangsaan Malaysia Malaysia 2020-11-01 2021-03-31 54898, NMRR-20-2131-54898 Phase Not Applicable Not yet recruiting 34 5 Months Siti Nurfadhilah binti Arsad 2020-10-19
Clinical study of an Ayurveda formulation containing Gold and Indian Gooseberry along with Tulasi juice as an add on therapy in standard care of COVID 19 patients Coronavirus disease 19 infection Swarna Amalaki alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ministry of Ayush Acharya Vinoba Bhave Rural Hospital India 2020-11-02 CTRI/2020/10/028414 Phase 2 Clinical Not yet recruiting 0 60 Anjalee Chiwane, Jyothy K B 2020-10-20
Psychological responses of medical staff during COVID-19 and the adjustment effect of brief mindfulness meditation Coronavirus disease 19 infection brief mindfulness meditation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Naval Medical Research Institute of PLA National Natural Science Foundation of China China 2021-01-01 2021-12-31 ChiCTR2000039002 Phase 0 Clinical Not yet recruiting 1 12 Months 400 Liu Yunzi 2020-10-19
School teachers experience in online teaching during this COVID-19 situation Acute stress disorder, Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Manipal Academy of Higher Education India 2020-10-13 CTRI/2020/10/028412 Phase Not Applicable Not yet recruiting 1 200 JOSHUA RAYMOND ANDRADE, UMESH THONSE 2020-10-21
A Phase III clinical trial for inactivated novel coronavirus pneumonia (COVID-19) vaccine (Vero cells) Coronavirus disease 19 infection, Viral pneumonia COVID-19 vaccine (inactivated, Vero cells/intramuscular), Wuhan Institute of Biological Products/Wuhan Institute of Virology, CAS alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) China National Biotec Group, Wuhan Institute of Biological Products Co Ltd Morocco 2020-09-02 2020-12-31 ChiCTR2000039000 Phase 3 Clinical Recruiting 1 3 Months 600 Professeur Abouqal Redouane, Wei Chen 2020-10-23
A population based survey on COVID-19 infection in Goa state among both urban and rural population Coronavirus disease 19 infection Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Government of Goa India 2020-10-16 CTRI/2020/10/028384 Phase Not Applicable Not yet recruiting 1 1000 Dr Dhananjay Lad, Dr Vijaykumar Patil 2020-10-20
Clinical characteristics and laboratory parameters of COVID-19 patients on oxygen Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) National Cancer Institute, Jhajjar, AIIMS India 2020-10-20 CTRI/2020/10/028340 Phase Not Applicable Not yet recruiting 1 100 Dr Anuja Pandit 2020-10-20
To study the relationship between spirituality,hope, distress and ability to bounce back from stress among family members of recovered COVID-19 patients Acute stress disorder, Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Government Medical College and Hospital,Chandigarh India 2020-11-01 CTRI/2020/10/028339 Phase Not Applicable Not yet recruiting 1 30 Anushka Negi, Dr Ajeet Sidana, Dr Manoj Kumar 2020-10-19
The Provider Insurance Revenue Study in Healthcare Providers in the United States of America Coronavirus disease 19 infection ND Sciences LLC University of California Irvine US 2020-10-01 2021-10-15 NCT04587245, PIRSTUDY Phase Not Applicable Recruiting 1 12 Months 100 Charles Bronson, Charles Bronson, MBA, Henry Broeska, Henry Broeska, PhD, Sheridan Merrick, BA 2020-11-05
NEUROCOV-19: Investigation of COVID-19 associated neurological comorbidities Coronavirus disease 19 infection, Neurological disease electrophysiological examination alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitatsklinikum Essen Germany 2020-10-25 20-9284-BO, DRKS00023312, NEUROCOV-19 Phase Not Applicable Recruiting 1 250 Mark Stettner, Michael Fleischer 2020-10-21
Dyhor-19: Diagnosis of Endocrine Dysfunctions in COVID-19 Coronavirus disease 19 infection, Endocrine disease Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Montpellier France 2020-03-01 2020-05-30 Dyhor-19, NCT04587375, RECHMPL20_0205 Phase Not Applicable Completed 1 2 Months 50 Philippe GUILPAIN, MD, PhD 2020-10-16
PROSPER: Pregnancy Outcomes During the Pandemic: Using Placental Pathology and Gene Expression to Understand Fetal Risk Coronavirus disease 19 infection Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Prisma Health-Upstate US 2020-08-04 2021-09-30 NCT04585945, PRO00101090, PROSPER Phase Not Applicable Recruiting 3 13 Months 100 Jessica Britt, PhD, Jessica L Britt, PhD 2020-10-16
Development and Use of a Post-COVID-19 Quality of Life Patient-reported Outcome Measure Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Medialis Ltd UK 2020-10-07 2025-10-31 MED-ASST 33, NCT04586413 Phase 1/Phase 2 Clinical Recruiting 1 60 Months 100 Ravi Jandhyala, Rose Watson 2020-11-05
An observational study to determine the postdischarge venous thromboembolism rates following hospital admission with COVID-19 Coronavirus disease 19 infection, Thromboembolism venous thromboembolism analysis alone Kings College Hospital NHS Trust Phase Not Applicable Status not specified 0 2020-10-18
MySteps-CoV: eHealth Intervention on Physical Activity for Type 2 Diabetics - Frustrated by COVID-19 Coronavirus disease 19 infection, Non-insulin dependent diabetes ExSed app alone, Usual care alone, counselling contacts alone, eHealth alone, hip-worn accelerometer alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) UKK-instituutti North Karelia Central Hospital, University Of Eastern Finland Finland 2019-03-06 2020-10-31 MYSTEPS ETL 303/2017, MySteps-CoV, NCT04587414 Phase Not Applicable No longer recruiting 1 19 Months 122 Harri Sievanen, Tommi Vasankari, MD, PhD 2020-10-20
Improving the Mental Health of Resident Physicians and Fellows Through Transcendental Meditation Acute stress disorder, Coronavirus disease 19 infection Transcendental meditation alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Arizona US 2020-11-30 2021-12-31 2008969193, NCT04586309 Phase Not Applicable Not yet recruiting 1 13 Months 50 Alison Sutton-Ryan, LCSW, Rachel E M Cramton, MD 2020-10-19
Endothelial dysfunction in severe COVID-19 disease Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute Of Medical Sciences, Rishikesh India 2020-10-19 CTRI/2020/10/028361 Phase Not Applicable Not yet recruiting 1 40 Rohit Walia 2020-10-21
Psychiatric sequelae in COVID-19 infection recovered resident doctors and interns of a tertiary health care hospital Coronavirus disease 19 infection, Psychiatric disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Seth GS Medical College India 2020-10-19 CTRI/2020/10/028360 Phase Not Applicable Not yet recruiting 1 60 Dr Neena S Sawant 2020-10-16
MoxiCov: Feasibility and Impact of Remote Oximetry in Patients Hospitalized With COVID-19 Coronavirus disease 19 infection, Hypoxia Digital oximeter alone, cardiac frequency monitoring alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo Brazil 2020-06-22 2021-06-22 5058/20/087, MoxiCov, NCT04587921 Phase Not Applicable Recruiting 1 12 Months 90 Daniel Queiróz, PhD, Diego Prieto, Msc, Geraldo Lorenzi Filho, Geraldo Lorenzi, M.D. PhD, Luciano Drager, M.D. PhD, Pedro Genta, M.D PhD 2020-10-16
A clinical trial to evaluate the effectiveness and safety of Vedicinals-9- a Herbal formulation in mild to moderate COVID-19 patients Coronavirus disease 19 infection Vedicinals-9 alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Vedicinals India Pvt Ltd India 2020-10-19 CTRI/2020/10/028364, EPRD0202-010920 Phase 2 Clinical Not yet recruiting 2 124 Dr Govinda Narke, Dr Nitin Shinde, Yogendra Kumar Choudhary 2020-11-05
The barriers encountered by health-service providers while giving healthcare to patients admitted to COVID hospitals of Odisha Coronavirus disease 19 infection online self-administered questionnaire alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Kalinga Institute of Medical Sciences India 2020-11-01 CTRI/2020/10/028363 Phase Not Applicable Not yet recruiting 1 1000 Nipa Singh 2020-10-16
The Study of 'Gam-COVID-Vac' Vaccine Against COVID-19 With the Participation of Volunteers of >/= 60 years old Coronavirus disease 19 infection Sputnik V alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gamalei Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation Collaborator Russian Federation 2020-10-22 2020-12-31 05-GAM-COVID-VAC-2020, NCT04587219 Phase 2 Clinical Recruiting 1 2 Months 110 Inna Dolzhikova, PhD, Nikita Lomakin, MD, PhD 2020-10-28
Study to assess the efficacy of deep breathing Pranayama technique in addition to conventional allopathic treatment in management of COVID-19 Coronavirus disease 19 infection deep breathing Pranayama alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Jagjivan Ram Hospital India 2020-10-15 CTRI/2020/10/028362, JRH/IEC/2020/COVID19/Pranayama breathing technique Phase Not Applicable Not yet recruiting 1 278 Dr Anuja Santosh Kulkarni 2020-11-05
Improving Cancer Screening and Prevention During the COVID-19 Pandemic in Underserved Populations of Rhode Island Breast tumor, Colorectal tumor, Coronavirus disease 19 infection Cancer screening alone, Colonoscopy alone, Informational videos and social media campaign alone, Mammogram alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rhode Island Hospital US 2020-08-28 2022-09-01 1613494-3, NCT04587258 Phase Not Applicable Recruiting 1 24 Months 100 Cristina Pacheco, MD, Don Dizon, MD, Howard Safran, MD 2020-10-17
Study to Assess the Effect of Meplazumab on COVID-19 Coronavirus disease 19 infection meplazumab alone, standard of care alone Basigin inhibitor, COVID19 Spike glycoprotein inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Pacific Meinuoke Biopharmaceutical 2020-10-30 2021-04-30 MPZ-II-02, NCT04586153 Phase 2/Phase 3 Clinical Not yet recruiting 0 6 Months 456 Shuangshuang Liu, Xiaochun Chen 2020-10-16
ETHICOVID: Operation of the GHPSJ Clinical Ethical Reflection Assistance Group During the COVID-19 Period Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Groupe Hospitalier Paris Saint-Joseph France 2020-11-09 2022-04-30 ETHICOVID, ETHICOVID, NCT04586140 Phase Not Applicable Not yet recruiting 1 17 Months 30 Helene BEAUSSIER, PharmD, pHD, Marie-Lorraine de WARREN, Nurse 2020-10-16
CoCovSDRA: Effect of Corticosteroid Treatment on Prognosis in ARDS Secondary to Covid-19 Coronavirus disease 19 infection, Respiratory distress syndrome corticosteroid treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Hospital, Nancy, France France 2020-03-01 2020-12-31 2020PI109, CoCovSDRA, DUBOST_2020_PI_109, NCT04586114 Phase Not Applicable No longer recruiting 1 10 Months 200 Sebastien GIBOT 2020-10-20
A trial to evaluate ALF-1001 for the preventing the spread of COVID-19 Coronavirus disease 19 infection ALF-1001 alone IL-22 antagonist, IL-23 antagonist, Interferon alpha 14 ligand, Interleukin 17A ligand inhibitor, Interleukin 17F ligand inhibitor, TNF alpha ligand inhibitor ILC Therapeutics Ltd Phase Not Applicable Planned 0 2020-10-15
A phase III clinical trial to evaluate the efficacy of SARS-CoV-2 peptide vaccine (li-Key, COVID-19), Generex for the potential prevention of COVID-19 infection Coronavirus disease 19 infection SARS-CoV-2 peptide vaccine (li-Key, COVID-19), Generex alone Generex Biotechnology Corp Bintai Kinden Corp US Phase 3 Clinical Planned 1 2020-10-15
A case-control study of lenzilumab in patients with severe and critical COVID-19 Coronavirus disease 19 infection lenzilumab alone GM-CSF ligand inhibitor, Immunoglobulin G1 modulator, Immunoglobulin kappa modulator Humanigen Inc Phase Not Applicable Status not specified 0 39 2020-10-15
A patient case report to evaluate lenzilumab in severe and critical COVID-19 patient Coronavirus disease 19 infection lenzilumab alone GM-CSF ligand inhibitor, Immunoglobulin G1 modulator, Immunoglobulin kappa modulator Male, European Ancestry Humanigen Inc Phase Not Applicable Status not specified 0 2020-10-15
VEGF and sFlt-1 Levels in the Pathogenesis and Severity of COVID-19 Disease Cardiac failure, Cardiovascular disease, Coronavirus disease 19 infection, Multiple organ failure, Renal failure, Respiratory failure Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Alabama at Birmingham US 2020-05-22 2023-05-20 IRB-300005378, NCT04587323 Phase Not Applicable Recruiting 1 35 Months 100 Dylan Addis, MD, Shanna H Graves 2020-10-16
A clinical trial of TLC-19 for the treatment of COVID-19 Coronavirus disease 19 infection TLC-19 alone Healthy volunteers accepted Taiwan Liposome Co Australia, Taiwan Phase 1 Clinical Recruiting 2 30 2020-10-24
MOR: Mouth Rinses for Inactivation of COVID-19 Coronavirus disease 19 infection Betadine gargle alone, Colgate Optic White alone, Colgate Total mouthwash alone, Listerine alone, Peridex alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of North Carolina US 2020-10-31 2023-09-30 20-2040, MOR, NCT04584684 Phase 2 Clinical Not yet recruiting 1 35 Months 480 Laura Jacox, DMD, PhD, S.T. Phillips, Wendy Lamm 2020-10-16
Outcomes of and Prognosis Factors for COVID-19 Patients - An Observational Study Coronavirus disease 19 infection Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Xiangya Hospital Of Central South University China 2020-01-17 2021-02-28 ChiCTR2000038943 Phase Not Applicable Recruiting 1 13 Months 233 Suixin Liu, Yaoshan Dun 2020-10-16
Gynecological Laparoscopic Surgery during COVID-19 Pandemic Coronavirus disease 19 infection, Gynecological disorder Putrajaya Hospital Malaysia 2020-09-30 2020-10-30 NMRR-20-2129-56450 Phase Not Applicable Status not specified 1 1 Month Dr Raimi Zamriah Hasan, Dr Tunisha a/p Ganisakran 2020-10-16
Biochemistry and hematology sample handling during COVID-19: Hospital Sungai Uloh experience Coronavirus disease 19 infection Hospital Sungai Buloh Malaysia 2021-01-25 2021-01-27 56713, NMRR-20-2127-56713 Phase Not Applicable Status not specified 1 Dr NUR AMALINA BINTI YUSOFF, Dr Sharifah Khairul Atikah 2020-10-19
A large, pragmatic, open-label study to assess efficacy and safety of bamlanivimab monotherapy or combination therapy with etesevimab Coronavirus disease 19 infection bamlanivimab alone, bamlanivimab plus etesevimab COVID19 Spike glycoprotein modulator Eli Lilly & Co Phase Not Applicable Planned 0 2020-10-15
ACTIV-3: A phase III, randomized, placebo-controlled clinical trial of bamlanivimab for the treatment of patients with ambulatory and hospitalized COVID-19 patients Coronavirus disease 19 infection standard care alone, bamlanivimab plus remdesivir COVID19 Spike glycoprotein modulator, COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Eli Lilly & Co, National Institute of Allergy and Infectious Diseases, National Institutes of Health ACTIV-3 Phase 3 Clinical Suspended 0 1000 2020-10-29
BLAZE-4: A clinical trial to evaluate IV doses of etesevimab in combination with bamlanivimab Coronavirus disease 19 infection bamlanivimab plus etesevimab COVID19 Spike glycoprotein inhibitor, COVID19 Spike glycoprotein modulator Eli Lilly & Co BLAZE-4 Phase Not Applicable Planned 0 2020-10-15
An observational study on the clinical characteristics of metastatic prostate cancer patients infected with COVID-19 in South Italy Coronavirus disease 19 infection, Hormone refractory prostate cancer, Metastatic prostate cancer LHRH agonist therapy alone, chemotherapy alone, enzalutamide alone, hormonal treatment alone Androgen receptor antagonist, Cytochrome P450 3A4 stimulator, DNA binding protein inhibitor, Prostate specific antigen modulator, Translocation associated protein inhibitor Male University of Molise Italy Phase Not Applicable Status not specified 1 2 2020-10-15
A Phase II Study of RTB-101 as COVID-19 Post-Exposure Prophylaxis in Older Adults Coronavirus disease 19 infection dactolisib alone Phosphoinositide 3-kinase inhibitor, mTOR complex 1 inhibitor, mTOR complex 2 inhibitor Aged Adults (65-79 yrs), Elderly Adults (80 and over) resTORbio Inc Harvard Medical School, National Institute on Aging, University of Connecticut Health Center US 2020-10-13 2021-02-28 3R01AG064802-02S1, NCT04584710, RTB101-211 Phase 2a Clinical Recruiting 2 4 Months 60 Lisa Kenyon-Pesce, Medical Monitor, Peggy Gagnon 2020-10-27
D-dimer Adjusted Versus Therapeutic Dose Low-molecular-weight Heparin in Patients With COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia D-dimer and weight adjusted therapy alone, enoxaparin sodium alone Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ain Shams University Egypt 2020-08-01 2020-12-31 FMASU P35/ 2020, NCT04584580 Phase 4 Clinical Recruiting 1 5 Months 50 Ashraf Madkour, Fatma Soliman E Ebeid 2020-10-16
OD-doxy-PNVCOV Old Drug 'DOXY' for Prevention of New Virus Virus OD-doxy-PNV Coronavirus disease 19 infection doxycycline plus zinc Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hopital Militaire Principal d'instruction de Tunis Dacima Consulting Tunisia 2020-10-30 2021-03-01 NCT04584567, UR17DN05 Phase 3 Clinical Not yet recruiting 1 4 Months 1100 Batikh R Riadh, physican, Ben Moussa M mohamed, physican, Ferjani M Mustapha, physican, Gharsallah H Hedi, physican, Mrabet A Ali, physican, Stambouli N nejla, phd, Youssfi MA Mohamed Al, physican 2020-10-15
The Effect of Aerobic Exercise on Immune Biomarkers and Symptoms Severity and Progression in Patients With COVID-19: A Pilot, Randomized, Control Trial Coronavirus disease 19 infection, Gastrointestinal disease, Upper respiratory tract infection, Viral pneumonia Moderate Intensity Aerobic Exercises alone, aerobic exercise alone, hydroxyclorocin sulphate (Plaquenil) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Istanbul Gelisim University Turkey 2020-01-01 2020-10-01 AEROBIC EXERCISE, COVID-19, NCT04581291 Phase Not Applicable Completed 1 9 Months 30 Motaz Alawna 2020-11-05
LIFTCOVID: Lift Mobile Mindfulness for COVID-19 Distress Symptoms Coronavirus disease 19 infection, Depression, Generalized anxiety disorder, Respiratory distress syndrome Lift mobile mindfulness program app alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Duke University National Center for Complementary and Integrative Health US 2020-11-01 2021-09-30 3U01AT009974-03S1, LIFTCOVID, NCT04581200, PRO00106306 Phase Not Applicable Not yet recruiting 4 11 Months 300 Allie Frear, Catherine L Hough, MD, MSc, Christopher Cox, MD, Christopher E Cox, MD, Jeffrey McKeehan, Lee Kamphuis, MPH, Madeleine McDougal, Marc Moss, MD, Theodore Iwashyna, MD, PhD 2020-10-16
SYNBIOTIC COV STUDY: An Evaluation of a Synbiotic Formula for Patients With COVID-19 Infection Coronavirus disease 19 infection health supplements (Synbiotic) alone, standard care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chinese University of Hong Kong Hong Kong 2020-08-13 2022-04-30 NCT04581018, SYNBIOTIC COV STUDY, SYNBIOTIC COV STUDY Phase Not Applicable Recruiting 1 20 Months 50 Amy Li, Kitty Cheung, Siew Chien Ng, Siew Chien Ng, PhD 2020-10-16
Remdesivir-HU Clinical Study and Severe Covid-19 Patients Coronavirus disease 19 infection, Viral pneumonia remdesivir alone COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hungarian Ministry of Innovation and Technology, University Of Pécs Hungary 2020-10-12 2021-11-30 2020-004928-42, NCT04610541, REM-ENY-01 Phase 3 Clinical Recruiting 8 13 Months 2000 CRO, Csaba Lengyel, István Várkonyi, Krisztina Bogos, Krisztina Hrács, PhD, Rita Kazinczy, dr, Veronika Müller, Zoltán Péterfi 2020-11-05
DYADS: Dysphagia and Dysphonia Outcomes in SARS CoV-2 (COVID-19) Infection Coronavirus disease 19 infection, Dysphagia, Dysphonia fiberoptic endoscopic evaluation of swallowing test alone, videofluoroscopy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cambridge University Hospitals NHS Foundation Trust UK 2020-09-15 2021-12-31 20/NW/0333, DYADS, NCT04584658 Phase Not Applicable Recruiting 1 15 Months 36 Andrie Schembri, BSc, Brian Fish, FRCS (ORL-HNS), Claudia Russell, MSc, Ekpemi Irune, Ekpemi Irune, FRCS (ORL-HNS), Liam Masterson, FRCS (ORL-HNS), Rachel Kyd, Sarah Pilsworth, MSc 2020-10-20
Patterns of Arrhythmias and Conduction Block in COVID-19 Patients and Its Relation to Myocardial Injury Detected by Cardiac Magnetic Resonance Atrioventricular block, Coronavirus disease 19 infection, Heart arrhythmia, Heart injury SSFP sequence based cine imaging alone, cardiac magnetic resonance imaging alone, gadolinium alone, myocardial perfusion imaging alone, tissue characterization imaging alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assiut University Egypt 2020-11-01 2024-01-01 ARRHYTHMIAS IN COVID-19, NCT04584411 Phase Not Applicable Not yet recruiting 1 38 Months 50 Ahmed AR Hassaan, bachelor, Alaa A El-Moniem, Doctorate, Doaa A Fouad, Doctorate, Maram M Shafiq, student, Mohamed A.H Abdelhafez, Doctorate, Shimaa S Khider, Doctorate 2020-10-15
Ain Shams University Experience: Clinical Determinants of Hospitalized COVID-19 Patients Coronavirus disease 19 infection laboratory test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ain Shams University Egypt 2020-06-27 2020-12-30 FMASU P30/ 2020, NCT04584606 Phase Not Applicable Recruiting 1 6 Months 100 Ashraf Elmaraghy, Fatma Soliman E Ebeid 2020-10-16
COPP2-study: Clinical features of COVID-19 in pediatric patients, long-term effects Coronavirus disease 19 infection Amsterdam UMC Netherlands 2020-10-01 2022-03-01 COPP2-study, NL8926 Phase Not Applicable Not yet recruiting 1 17 Months 120 Caroline Kosterink-Brackel 2020-10-15
LIVECOVIDFREE: Lung Structure-Function In Survivors of Mild and Severe COVID-19 Infection Coronavirus disease 19 infection 6 min walk test alone, biological sampling alone, computed tomography alone, forced oscillation technique alone, hyperpolarized xenon-129 alone, magnetic resonance imaging alone, plethysmography alone, spirometry alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Western Ontario London Health Sciences Centre Research Inc Canada 2020-12-01 2024-12-01 LIVECOVIDFREE, NCT04584671, ROB0050 Phase Not Applicable Not yet recruiting 1 48 Months 200 Angela Wilson, RRT, Grace E Parraga, PhD 2020-11-06