Last updated: Nov 24, 2020 - 02:00 GMT

Title Indication Intervention Actions PatientSelection Sponsor Collaborator Country StartDate EndDate Identifiers Phase Recruitment Status Sites Trial Duration Enrollment Count Contacts LastChanged
Ampligen in Chronic Fatigue Syndrome Chronic fatigue syndrome, Coronavirus disease 19 infection rintatolimod alone 2,5-Oligoadenylate synthetase stimulator, Interferon type I receptor agonist, Ribonuclease stimulator, TLR-3 agonist Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) AIM ImmunoTech Inc US AMP 511, NCT00215813 Phase 3 Clinical Recruiting 2 Ann Marie Coverly, Charles Lapp, MD, Charles W. Lapp, M.D., Daniel Peterson, M.D., Daniel Peterson, MD, Diane Young 2020-10-27
A virtual global clinical trial to assess ePRO measures using Migraine Buddy mobile tracking app for an acute migraine medication in COVID-19 pandemic Coronavirus disease 19 infection, Migraine Migraine Buddy mobile tracking app alone Healint Pte Ltd 2020-11-18 COVID19_IMPACT Phase Not Applicable Recruiting 0 2020-11-23
Effect of Home Exercise Activity on Cortisol and Depression in COPD During the Pandemic COVID Chronic obstructive pulmonary disease, Coronavirus disease 19 infection, Depression bicycle alone, moderate intensity home-exercise training alone, treadmill alone, upper and lower limb exercise alone Male, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Cairo University Egypt 2020-11-19 2021-03-01 NCT04639349, P.T.REC/012/002897 Phase Not Applicable Recruiting 0 3 Months 40 Ali Ismail, lecturer, Ali Mohamed Ali ismail 2020-11-23
Testing Scalable, Single-Session Interventions for Adolescent Depression in the Context of COVID-19 Coronavirus disease 19 infection, Depression behavioral activation SSI alone, growth mindset SSI alone Adolescents (13-17 yrs) State University of New York at Stony Brook University of Denver US 2020-11-30 2021-07-31 1505797-3, NCT04634903 Phase Not Applicable Not yet recruiting 0 8 Months 2400 Jessica L Schleider, PhD 2020-11-23
Targeting the Health Care Provider (HCP) Burnout Crisis During the COVID-19 Pandemic Acute stress disorder, Coronavirus disease 19 infection Transcendental meditation alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Duke University US 2020-11-30 2021-04-30 NCT04632368, PRO00106191 Phase Not Applicable Not yet recruiting 0 5 Months 80 Catherine Clinical Research Co-ordinator, Taylor Clinical Research Co-ordinator 2020-11-23
BRIDGE: Building Regulation in Dual Generations - Telehealth Model Coronavirus disease 19 infection, Depression BRIDGE therapy program alone, dialectical behavior therapy alone Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Manitoba Centre for Addiction and Mental Health, Research Manitoba, University of Oregon Canada 2020-09-01 2021-05-31 BRIDGE, BRIDGEV2.0, NCT04639557 Phase Not Applicable Recruiting 0 9 Months 40 2020-11-23
EUDOCO: Early Versus Delayed Intubation of Patients With COVID-19 Coronavirus disease 19 infection, Hypoxia, Respiratory failure endotracheal intubation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Evangelismos Hospital Greece 2020-11-18 2021-05-01 32635, 13-10-2020, EUDOCO, NCT04632043 Phase Not Applicable Not yet recruiting 0 5 Months 80 Ilias Siempos, MD, DSc 2020-11-23
Patient Centered Intervention to Prevent Tuberculosis Among Children < 5 Years Old Coronavirus disease 19 infection, Mycobacterium tuberculosis infection educational booklet alone, isoniazid alone, isoniazid preventive therapy alone, weekly SMS alone, weekly children storybook session alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidad Peruana Cayetano Heredia Peru 2019-12-01 2023-12-15 103161, NCT03881228 Phase 2 Clinical Recruiting 0 48 Months 300 Larissa Otero, MD PhD, Larissa Otero, PhD 2020-11-23
Telepsychoeducation for the Prevention of Emotional Distress in Professionals and Students From Essential Services in the Context of COVID-19 Acute stress disorder, Coronavirus disease 19 infection telepsychoeducation with personalized videos alone Hospital de Clinicas de Porto Alegre Brazil 2020-11-05 2021-07-20 20200213_PREVENTION, NCT04632082 Phase Not Applicable Recruiting 0 8 Months 2200 Giovanni Salum, MD, PhD 2020-11-23
The Effect of Ganglion Sphenopalatine Block (SPG-block) Versus Placebo on Persistent Headache Following Acute COVID-19 Infection Coronavirus disease 19 infection, Headache ganglion sphenopalatine block (SPG block) alone, lidocaine plus ropivacaine Sodium channel inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Bispebjerg and Frederiksberg Denmark 2020-12-31 2021-11-30 GSPB-COVID-2020, NCT04636034 Phase 3 Clinical Not yet recruiting 0 11 Months 60 Christian S Meyhoff, PhD, Mads S Jespersen, MD, Mads Seit Jespersen 2020-11-23
COVID_CRC: The Impact of Covid-19 Pandemic on Colorectal Cancer Prevention Due to Delays in Diagnosis: a Global Study Colorectal tumor, Coronavirus disease 19 infection Colonoscopy alone Istituto Clinico Humanitas Italy 2020-12-16 2021-03-31 100, COVID_CRC, NCT04637893 Phase Not Applicable Not yet recruiting 0 3 Months 1000 Alessandro Repici, MD, Roberta Maselli, MD 2020-11-23
Online Trial of Meditation and Behavior Coronavirus disease 19 infection Loving-Kindness Meditation training alone, Relaxation Meditation training alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Georgetown University US 2020-11-20 2021-11-20 2010-180-2, NCT04632875 Phase Not Applicable Recruiting 0 12 Months 68 Abigail A Marsh, PhD, Study Coordinator 2020-11-23
NeuroCovid Rehab and Recovery Related to COVID-19 Diagnosis Coronavirus disease 19 infection, Neurological disease Soterix taVNS model 0125-LTE stimulator alone, transcutaneous auricular vagus nerve stimulation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Medical University of South Carolina National Institute of General Medical Sciences, National Institutes of Health US 2020-11-30 2021-06-30 00101270, NCT04638673, U54GM104941-08 Phase 2 Clinical Not yet recruiting 0 7 Months 30 Mark S George, MD, Morgan Dancy, BA, Sarah Huffman, BA 2020-11-23
Prayer in Commbate to Corona Virus - COVID-19 Coronavirus disease 19 infection prayers by theologians alone, protcol treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital do Coracao Brazil 2020-08-01 2021-01-31 NCT04631380, PRAYER-COVID19 Phase Not Applicable Recruiting 0 6 Months 200 Alexandre B Cavalcanti, MD, PhD, NATHAN V SOUBIHE JR, sabrina bernardez 2020-11-23
Video Home Visits for Dietary Counselling Coronavirus disease 19 infection, Urolithiasis urologist and dietitian virtual home visits alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of California San Francisco US 2021-01-01 2024-07-01 NCT04634851, UCSFUROVV Phase Not Applicable Not yet recruiting 0 42 Months 100 David Bayne, MD, MPH, Marshall Stoller, MD 2020-11-23
UNITED: At-Home Infusion Using Bamlanivimab in Participants With Mild to Moderate COVID-19 Coronavirus disease 19 infection bamlanivimab alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Aged Adults (65-79 yrs), Elderly Adults (80 and over) UnitedHealth Group Inc Eli Lilly & Co, Optum Inc 2020-11-30 2021-05-31 2020-0081, NCT04639479, UNITED Phase 4 Clinical Not yet recruiting 0 6 Months 7500 Dan Griffin, MD PHD, Michelle Tanner, BA, Tracy Ziolek, MS 2020-11-23
Online Multi-component Psychological Intervention for Prevention of Grief Disorder Due to COVID-19 Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder, Sleep disorder Multi-component psychological online intervention alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Universidad Internacional de Valencia Universidad Autonoma de Ciudad Juarez, Universidad Nacional Autonoma De Mexico, University of Buenos Aires Mexico 2020-12-15 2021-06-01 NCT04638842, VIU-GRIEF-COVID Phase Not Applicable Not yet recruiting 0 5 Months 42 Alejandro Dominguez Rodriguez, PhD, Anabel de la Rosa, Gómez, Carlos Armando Arzola, MD, Esteban Eugenio Esquivel Santoveña, PhD, Flor Rocío Ramírez Martínez, PhD, Luis Farfallini, PhD, María Jesús Hernández Jimenez, PhD, Paulina Arenas Landgrave, PhD, Rosa Olimpia Castellanos Vargas, MD, Sofía Cristina Martínez Luna, MD 2020-11-23
An observational, retrospective, propensity-matched study to evaluate the impact of famotidine use on clinical outcomes of hospitalized patients with COVID-19 Coronavirus disease 19 infection famotidine alone Histamine H2 receptor antagonist Hartford Hospital Phase Not Applicable Status not specified 0 878 2020-11-23
CureCovid-2019: A Study to Compare the Efficacy of GNS-561 Versus Standard of Care in Patients With SARS-CoV-2 (COVID-19) Infection Coronavirus disease 19 infection GNS-561 alone, standard of care alone Autophagy protein inhibitor, Solute carrier family inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Genoscience France 2020-11-18 2021-10-30 CureCovid-2019, GNS561-CL-I-Q-0291, NCT04637828 Phase 2 Clinical Recruiting 0 11 Months 178 Christelle Ansaldi, Christelle Ansaldi, MD 2020-11-23
Polio Vaccine (IPV) for SARS-CoV-2 and Prevention of Coronavirus Disease (COVID-19) Coronavirus disease 19 infection polio vaccine, Sanofi Pasteur alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) US 2020-11-15 2021-01-15 EMO-001, NCT04639375 Phase 0 Clinical Recruiting 0 2 Months 25 Brittany Comunale, John Andrews, John Andrews, PhD 2020-11-23
COVIFAT: Impact of Adipose Tissue in COVID-19 Coronavirus disease 19 infection, Inflammatory disease, Obesity adipose tissue sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-11-23 2021-11-23 2020-A02403-36, APHP200983, COVIFAT, NCT04639440 Phase Not Applicable Not yet recruiting 0 12 Months 60 Fabienne FOUFELLE, Dr, Olivier BOURRON, Dr 2020-11-23
A phase III trial of AMY-101 for the treatment of severe COVID-19 patients Coronavirus disease 19 infection AMY-101 alone Complement C3 inhibitor University of Pennsylvania Brazil Phase 3 Clinical Planned 0 2020-11-23
The effect of massage training on the resilience of pregnant women Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression telemedicine-based massage training alone Female, Young Adults (18-44 yrs) Islamic Azad University Iran 2020-11-04 IR.IAU.MSHD.REC.1399.159, IRCT20170607034378N2 Phase Not Applicable Recruiting 0 120 Ali Asghar Mahmudi, Dr Saeed Khayat Moghadam, Fatemeh Jalal Marvi, Mahdi Sayad Kame Olya 2020-11-23
The role of hemoperfusion in COVID-19 Coronavirus disease 19 infection, Respiratory failure Standard of care treatment alone, hemoperfusion alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shaheed Beheshti Medical University Iran 2020-10-17 IR.SBMU.RETECH.REC.1399.582, IRCT20200608047686N2 Phase 2 Clinical Recruiting 0 40 Afshin Zarghi, Muhanna Kazempour 2020-11-23
Qualitative Study: Issues Faced by Female Staffs During the Pandemic COVID-19 Coronavirus disease 19 infection Hospital Tuanku Fauziah Malaysia 2020-11-23 2021-04-30 57017, NMRR-20-2507-57017 Phase Not Applicable Not yet recruiting 0 5 Months Dr Noor Melissa Binti Nor Hadi 2020-11-23
TECOVID: Thrombotic Complications Among COVID-19 Patients: A Multicenter Study from a Malaysian Perspective Coronavirus disease 19 infection, Phlebothrombosis Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universiti Teknologi Mara Malaysia 2020-12-01 2021-11-30 56439, NMRR-20-2465-56439, TECOVID Phase Not Applicable Status not specified 0 12 Months 3035 Dr Hanis Hanum Zulkifly, Dr Lee Chew Kiok, Dr Leong Chee Loon 2020-11-23
Cross-Sectional Study: Factors Contributing to Burnout Among Healthcare Workers in Sabah Coronavirus disease 19 infection Hospital Tuanku Fauziah Malaysia 2020-12-01 2021-04-30 57139, NMRR-20-2494-57139 Phase Not Applicable Not yet recruiting 0 5 Months Dr Noor Melissa Binti Nor Hadi 2020-11-23
Management of Depression and Anxiety in HF Anxiety disorder, Cardiac failure, Coronavirus disease 19 infection, Depression web-based COMPASS intervention alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) King's College London UK 2020-10-02 2021-08-16 IRAS ID: 268951, NCT04636944 Phase Not Applicable Recruiting 0 10 Months 13 Annmarie Grealish, Catherine Evans, Sameera Helal, Silapiya Smith 2020-11-22
An observational, retrospective, cohort study to investigate the potential hepatotoxicity of lopinavir/ritonavir in severely ill patients for the treatment of COVID-19 infection Coronavirus disease 19 infection lopinavir + ritonavir alone HIV protease inhibitor Centre Hospitalier Regional Universitaire de Lille Phase Not Applicable Status not specified 0 42 2020-11-22
Short Term Effects in Pulmonary Function Among COVID-19 Recovered Adult Patients in a Tertiary Hospital in Davao City Coronavirus disease 19 infection, Dyspnea Southern Philippines Medical Center Philippines 2021-01-18 2021-04-18 PHRR201110-003113 Phase Not Applicable Not yet recruiting 1 3 Months Benjo P. Ato, Christoper John Q. Quadra 2020-11-23
COVID-CMR: Prevalence of Myocardial Scars on CMR After COVID-19 Infection Coronavirus disease 19 infection, Myocardial disease Cardiac Magnetic Resonance Imaging alone, ECG monitoring alone, treadmill exercise test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Bordeaux Universite de Bordeaux France 2020-06-13 2021-04-13 CHUBX 2020/22, COVID-CMR, NCT04636320 Phase Not Applicable Recruiting 1 10 Months 240 Hubert COCHET, MD-PhD, Nathalie COTTIGNIES, Pierre JAïS, MD-PhD 2020-11-23
Phase I Trial of a Recombinant SARS-CoV-2 Vaccine (CHO Cell) Coronavirus disease 19 infection SARS-CoV-2 vaccine (CHO Cell) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry Jiangsu Province Centers for Disease Control and Prevention Chinese Academy of Medical Military Sciences, Liaoning Maokangyuan, Zhongyi Anke Biotechology Co Ltd China 2020-10-30 2022-01-07 JSVCT096, NCT04636333 Phase 1 Clinical Recruiting 0 14 Months 216 Fanyue Meng, Doctor, Fengcai Zhu, Doctor, Mingwei Wei 2020-11-23
Effect of Vitamin D on Hospitalized Adults With COVID-19 Infection Coronavirus disease 19 infection cholecalciferol alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Liege Laboratoires SMB SA Belgium 2020-11-12 2021-02-28 D-COVID, NCT04636086 Phase 4 Clinical Recruiting 1 3 Months 100 Anne-Françoise Rousseau, Anne-Françoise Rousseau, MD, PhD 2020-11-23
PEACE: Perceptions, Experiences, and Activity in Cancer Survivors During COVID-19 Cancer, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Nebraska US 2020-12-01 2021-06-30 768-20, NCT04637295, PEACE Phase Not Applicable Not yet recruiting 1 7 Months 1000 Diane K Ehlers, PhD, Lindsey Page, MS, Nicholas J Foggia, MS 2020-11-21
A clinical trial of light activated photodynamic compound vaccine (COVID-19 infection), Theralase Technologies/University of Manitoba for the potential treatment of COVID-19 infection Coronavirus disease 19 infection light activated photodynamic compound vaccine (COVID-19 infection), Theralase Technologies/University of Manitoba alone Theralase Technologies Inc Phase Not Applicable Planned 0 2020-11-21
Methylene Blue Treatment of COVID-19 Coronavirus disease 19 infection methylene blue alone, standard therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Epatocentro Ticino Foundation Switzerland 2020-11-30 2022-12-31 MB TREATMENT OF COVID19, NCT04635605 Phase 2 Clinical Not yet recruiting 1 25 Months 64 Andreas Cerny, Prof, Maurizia Bissig 2020-11-21
MEDEAS: Methylprednisolone Versus Dexamethasone in COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia methylprednisolone alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) L'Universita Degli Studi di Trieste Centro Di Riferimento Oncologico (CRO Aviano), Istituto Nazionale Per Le Malattie Infettive "Lazzaro Spallanzani" Italy 2020-11-25 2021-04-30 MEDEAS, MEDEAS1, NCT04636671 Phase 3 Clinical Not yet recruiting 1 5 Months 680 Francesco Salton, MD, Marco Confalonieri, MD 2020-11-21
KORANIT: Serological Diagnostics of SARS-CoV2 in Health Care Workers Coronavirus disease 19 infection blood test alone, nasal swab test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University Medical Centre Ljubljana Slovenia 2020-11-30 2021-01-31 KOAIT-1-2020, KORANIT, NCT04635592 Phase Not Applicable Not yet recruiting 1 2 Months 300 Marko Zlicar, MD, PhD, Peter Poredos, Assist. prof, Peter Poredos, MD, PhD 2020-11-23
An observational comparative study on the effects of second week methylprednisolone pulses in patients with severe coronavirus disease 2019 pneumonia Coronavirus disease 19 infection, Pneumonia methylprednisolone alone Hospital de Cruces Spain Phase Not Applicable Status not specified 1 242 2020-11-20
Study of a Recombinant Coronavirus-Like Particle COVID-19 Vaccine in Adults Coronavirus disease 19 infection MT-2766 alone TLR-9 agonist Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Medicago Inc GlaxoSmithKline plc Europe, Canada, North America, US 2020-11-19 2022-04-30 CP-PRO-COVLP-021, NCT04636697 Phase 2/Phase 3 Clinical Not yet recruiting 2 17 Months 30612 Brian Ward, MD, Mary Hardison 2020-11-23
Personalized Phage Treatment in COVID-19 Patients With Bacterial Co-Infections Microbials for Pneumonia or Bacteremia/Septicemia Acinetobacter baumannii infection, Bacterial infection, Coronavirus disease 19 infection, Pseudomonas aeruginosa infection, Sepsis, Staphylococcus aureus infection, Viral pneumonia Phage Therapy alone, anti-microbial therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Adaptive Phage Therapeutics Inc APT.APS.001, NCT04636554 Phase Not Applicable Recruiting 0 Robert J Hopkins, MD, MPH&TM, FACP, FIDSA, Stephanie Holland 2020-11-20
Burden of SARS-CoV-2 Infection in Populations With High or Low Risk of Infection Coronavirus disease 19 infection, Post traumatic stress disorder app alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Neuromed IRCCS Italy 2020-12-15 2022-06-15 DEP_032020, NCT04636203 Phase Not Applicable Not yet recruiting 1 18 Months 3500 Chiara Cerletti, MS, Licia Iacoviello, MD, PhD 2020-11-23
A large clinical diagnostic study to assess COVID-19 in exhaled breath condensate (EBC) using CoronaCheck diagnostic test Coronavirus disease 19 infection CoronaCheck diagnostic test alone Exhalation Technology Limited UK 2020-11-02 Phase Not Applicable Recruiting 1 300 Anoop Chauhan 2020-11-20
Immune Profiling with Antibody-based COVID-19 Testing Coronavirus disease 19 infection, Multiple myeloma Antibody-based COVID-19 Testing alone African Ancestry Quest Diagnostics Inc Dana-Farber Cancer Institute Inc US Phase Not Applicable Status not specified 1 1000 Irene Ghobrial, MD 2020-11-20
Vital Sensor Monitors for CV19 Detection Coronavirus disease 19 infection ANNE One wireless vital sign monitoring device alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Northwestern University US Department of Defense US 2020-11-05 2022-10-30 NCT04635787, STU00213040 Phase Not Applicable Recruiting 1 23 Months 300 Shuai (Steve) Xu 2020-11-23
RECIPE: Restoring Non-Emergent Cardiovascular Care in the Peri- COVID-19 Era Coronavirus disease 19 infection cardiac procedures alone Healthy volunteers accepted Pinnacle Health US 2020-08-01 2022-06-30 NCT04636021, RECIPE, UPMCP- 20-007 Phase Not Applicable Recruiting 1 23 Months 1000 William Bachinsky MD, William Bachinsky, MD 2020-11-20
INHALE-HEP: Inhaled Heparin for Hospitalized COVID-19 Patients Coronavirus disease 19 infection standard care alone, unfractionated heparin alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The Australian National University Helwan University Argentina, Egypt 2020-06-01 2021-06-01 INHALE-HEP, INHALE-HEP META-TRIAL, NCT04635241 Phase 2/Phase 3 Clinical Recruiting 2 12 Months 656 Alicia B Vilaseca, PhD, Frank MP van Haren, MD, PhD, Frank van Haren, Tarek I Ismail 2020-11-21
H2Covid: Hydrogen Therapy in Patients With Moderate Covid-19 Coronavirus disease 19 infection conventional oxygen therapy alone, hydrogen therapy alone, nasal cannula alone, Variable regimens including hydrogen , nitrogen , oxygen Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Grenoble France 2020-12-01 2021-09-30 38RC20.277, H2Covid, NCT04633980 Phase 1 Clinical Not yet recruiting 1 10 Months 10 BOUCHER François, PhD, Jean Paul Brion, MD, Saber TOUATI, PhD 2020-11-23
Impact of Social Distancing on Bariatric Versus Non-Surgical Obese Patients During COVID-19 Pandemic Coronavirus disease 19 infection Post bariatric surgery alone, Standard care alone, active medical management alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Singapore General Hospital Pte Ltd Singapore 2020-06-01 2020-07-30 HENRYLEW, NCT04633941 Phase Not Applicable Completed 1 1 Month 272 Chin Hong Lim, FRCS 2020-11-20
Borderline COVID-19 PCR Test Result Coronavirus disease 19 infection PCR test alone Jessa Hospital Belgium 2020-08-01 2020-12-30 F/2020/166, NCT04636294 Phase Not Applicable No longer recruiting 1 4 Months 30000 2020-11-20
The Impact of COVID-19 Pandemic on Thyroid Surgery in Italy: Results From a Nation-wide, Multicentric Study Coronavirus disease 19 infection, Thyroid disease Thyroidectomy alone University of Cagliari Italy 2020-03-10 2020-11-12 NCT04635813, THYCOVIT Phase Not Applicable Completed 1 8 Months 3800 Fabio Medas 2020-11-23
PallPan AP 4: COVID-19: National strategy for palliative care during times of a pandemic - generalst palliative care in hospitals Coronavirus disease 19 infection focus group interview alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitätklinikum Düsseldorf Bundesministerium für Bildung und Forschung Germany 2020-12-01 2020-1119, DRKS00023595, PallPan AP 4 Phase Not Applicable Not yet recruiting 1 30 Martin Neukirchen 2020-11-23
A phase I clinical trial of TNX-1800 for the potential prevention of COVID-19 infection Coronavirus disease 19 infection TNX-1800 alone COVID19 Spike glycoprotein modulator Tonix Pharmaceuticals Holding Corp Phase 1 Clinical Planned 0 2020-11-20
A phase III trial of PegiHep for the treatment of COVID-19 Coronavirus disease 19 infection peginterferon alfa-2b follow-on-biologic, Zydus-Cadila alone Interferon alpha 2 ligand Zydus-Cadila Group India Phase 3 Clinical Planned 1 2020-11-21
Effect of Ivermectin in treatment of COVID-19 Coronavirus disease 19 infection Variable regimens including Lopinavir/Ritonavir , hydroxychloroquine sulfate , interferon beta-1a follow-on biologic (intramuscular), CinnaGen , ivermectin Chloride channel modulator, Interferon beta ligand Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bandare-abbas University of Medical Sciences Iran 2020-11-15 2021-02-15 IR.HUMS.REC.1399.410, IRCT20200506047323N6 Phase 3 Clinical Recruiting 1 3 Months 120 Mahdi Hasani Azad, Mohammad Fathalipour 2020-11-23
Phase I Clinical Trial on NK Cells for COVID-19 Coronavirus disease 19 infection natural killer cells alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital de Clinicas de Porto Alegre Brazil 2021-01-02 2021-03-30 20200210, NCT04634370 Phase 1 Clinical Not yet recruiting 1 2 Months 24 Annelise Pezzi, PhD, Lucia Silla, MD, PhD, Lucia Silla, Md, PhD 2020-11-20
COV-HD: Antibody Response in Hemodialysis and Non-dialysis Patients Diagnosed With COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Saint Petersburg State University Russian Federation 2020-11-30 2021-08-31 COV-HD, COVID, NCT04633915 Phase Not Applicable Not yet recruiting 1 9 Months 40 Ekaterina Parshina 2020-11-20
An observational study on the factors associated with prolonged viral shedding and impact of lopinavir/ritonavir treatment in hospitalized non-critically ill patients with SARS-CoV-2 infection Coronavirus disease 19 infection lopinavir + ritonavir alone HIV protease inhibitor Zhengzhou University China Phase Not Applicable Status not specified 1 120 2020-11-19
Ezrin Peptide (HEP-1) for Treatment of Coronavirus Disease (COVID-19) Infection Coronavirus disease 19 infection Gepon alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Shaheed Beheshti Medical University praxisgemeinschaft für zelltherapie Iran 2020-12-20 2021-04-01 IR.SBMU.REC.1399.023, NCT04627233 Phase 1 Clinical Not yet recruiting 1 3 Months 20 Farzad Ashrafi 2020-11-22
A Study Evaluating the Efficacy and Safety of CKD-314 in Hospitalized Adult Patients Diagnosed With COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia nafamostat (COVID-19 infection), Institut Pasteur Korea alone, standard of care alone Serine protease inhibitor, Transmembrane serine protease 2 inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chong Kun Dang Pharmaceutical Corp South Korea 2020-11-20 2021-06-30 A108_01CVD2013, NCT04628143 Phase 2 Clinical Not yet recruiting 1 7 Months 100 Dongho Kim, MD 2020-11-19
The Severity of COVID-19 in Diabetes and Non-diabetes Patients (COVID-19) Coronavirus disease 19 infection, Diabetes mellitus Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dr. A. Ramachandran's Diabetes Hospitals, India Diabetes Research Foundation India 2020-11-16 2021-05-16 IDRFARH015, NCT04634214 Phase Not Applicable Not yet recruiting 4 6 Months 1050 Ambady Ramachandran, M.D,PhD,DSc, Palaniappan T, M.D, Sruti Chandrasekaran, M.D.,D.M, Su Thillai Vallal, M.D, Subair Khan, M.S 2020-11-23
STOP Severe COVID-19: Study To antagonize Plasminogen Activator Inhibitor-1 in Severe COVID-19 Coronavirus disease 19 infection TM-5614 alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Northwestern University US 2020-11-16 2022-06-30 NCT04634799, STOP Severe COVID-19, STU00213262 Phase 1/Phase 2 Clinical Recruiting 1 19 Months 80 Anna Huskin, RN, Douglas E Vaughan, MD, Lyndsay Christensen, MSN, Sanjiv J Shah, MD, Sanjiv Shah, MD 2020-11-23
MP-COVID: The MentalPlus for Assessment and Rehabilitation of Cognitive Function After Remission of the Symptoms of COVID-19 Cognitive disorder, Coronavirus disease 19 infection MentalPlus digital game alone Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Sao Paulo Brazil 2020-11-08 2023-12-29 MENTALPLUS, MP-COVID, NCT04632719 Phase Not Applicable Recruiting 1 37 Months 200 Julia S Valentin, Fellow, Julia S. Valentin, Fellow, Julia SS Valentin, Bacharel, Livia S. Valentin, Ph.D, Livia S. Valentin, Ph.D., Livia SS Valentin, Ph.D, Livia Stocco S Valentin, Ph.D, Luiz Antonio M Cesar, Ph.D, Luiz Aparecido Bortolotto, Ph.D 2020-11-20
EpiSARS2: Prevalence and Risk Factors of COVID-19 in the Upper Silesian Agglomeration Coronavirus disease 19 infection Healthy volunteers accepted Slaski Uniwersytet Medyczny w Katowicach Poland 2020-06-22 2021-04-22 2020/ABM /COVID19/0044, EpiSARS2, NCT04627623 Phase Not Applicable Recruiting 1 10 Months 6000 Grzegorz M Brozek, Prof, Jan E Zejda, Prof, Prof. Grzegorz Brożek,, Rafał Trela 2020-11-23
Assessment of Stress, Depression and Anxiety in Healthcare Caring for Patients With COVID-19 Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression, Sleep disorder Beck's Test alone, COPE test alone, Test PSS alone, Test STAI alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Jagiellonian University Poland 2020-07-01 2021-12-31 1072.6120.161.2020, NCT04631497 Phase Not Applicable Recruiting 1 18 Months 100 Tomasz Skladzien, Ph.D. M.D, Tomasz Skladzien, Ph.D. M.D., Tomasz Skladzien, PhD 2020-11-23
Exploratory Phase I Trial of the Active IMP in Healthy Volunteers in Relation to COVID-19 Coronavirus disease 19 infection ivermectin (extended release/sc/BEPO, COVID-19), MedinCell alone Healthy volunteers accepted, Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) MedinCell SA MAC Clinical Research UK 2020-09-22 2021-05-31 MDC-TTG-CT-001, NCT04632706 Phase 1 Clinical Recruiting 1 8 Months 24 Chief Development Officer, Joel Richard, L Cheung, P M Leung, R Kelshaw 2020-11-20
An European clinical study to assess RLF-100 in the treatment of patients with COVID-19 induced lung injury Coronavirus disease 19 infection, Lung injury aviptadil (inhaled, sarcoidosis/acute lung injury/acute respiratory distress syndrome associated COVID-19), Relief Therapeutics Holding alone Adrenergic receptor antagonist, VIP receptor agonist Relief Therapeutics Holding AG Syneos Health Inc Europe 2021-03-31 Phase Not Applicable Planned 0 2020-11-19
MEDIC-LAUMC: Managing Endothelial Dysfunction in COVID-19: A Randomized, Controlled Trial at LAUMC Coronavirus disease 19 infection, Dyspnea, Respiratory distress syndrome, Vascular disease anticoagulation therapy alone, Variable regimens including L-arginine , atorvastatin , dexamethasone , folic acid , nebivolol , nicorandil , vitamin C , zinc Beta 1 adrenoceptor antagonist, Beta 3 adrenoceptor agonist, HMG CoA reductase inhibitor, Potassium channel stimulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) LAU Medical Center Lebanon 2020-11-10 2021-05-01 LEBANESE AMERICAN UNIVERSITY, MEDIC-LAUMC, NCT04631536 Phase 0 Clinical Not yet recruiting 1 5 Months 80 Kamal Matli, Matli Kamal, MD 2020-11-23
A phase IIb, confirmatory study of Zofin in the treatment of patients with COVID-19 infection Coronavirus disease 19 infection Zofin alone Organicell Regenerative Medicine 2021-03-31 Phase 2b Clinical Planned 0 2020-11-19
IvermecPrev-Brazil: Study on the effects of using ivermectin to prevent COVID-19 in an adult population in Brazil Coronavirus disease 19 infection ivermectin alone Chloride channel modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidade Federal de Pernambuco University of Toronto Brazil 2020-04-10 2021-06-30 ISRCTN90437126, IVERMECPREV-BRAZIL SCINETN001.2020, IvermecPrev-Brazil Phase 3 Clinical Recruiting 1 14 Months 800 Prof Denia Fittipaldi-Duarte, Prof deCastro 2020-11-20
EAVE II: Early Pandemic Evaluation and Enhanced Surveillance of the coronavirus COVID-19 Coronavirus disease 19 infection vaccine programmes alone Academic and Clinical Centre Office for Research and Development [ACCORD], UK UK 2020-03-01 2021-09-30 EAVE II, IRAS 114474, ISRCTN40292537 Phase Not Applicable Recruiting 2 19 Months 5400000 Prof Sheikh 2020-11-19
Cash transfers to stimulate school re-enrollment among vulnerable adolescent girls in urban informal settlements as Kenya responds to COVID-19 Coronavirus disease 19 infection one-time cash transfer alone Healthy volunteers accepted, Female Population Council - Kenya Bill & Melinda Gates Foundation, Department for International Development, Echidna Giving Kenya 2020-10-02 2021-06-30 ISRCTN12792822, P661 Phase Not Applicable Not yet recruiting 1 8 Months 1700 Dr Austrian 2020-11-20
COVID-19 - Administration of the SARS-CoV-2-Neutralizing Monoclonal Antibody DZIF-10c (Inhalation) Coronavirus disease 19 infection DZIF-10c alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Cologne Boehringer Ingelheim International GmbH, The Clinical Trials Centre Cologne Germany 2020-11-23 2021-06-30 NCT04631705, UNI-KOELN-4370 Phase 1/Phase 2 Clinical Not yet recruiting 1 7 Months 69 Florian Klein, Univ.Prof., Gerd Fätkenheuer, Henning Gruell, Dr. med. 2020-11-23
APEL-COVID: Apelin; ACE2 and Biomarkers of Alveolar-capillary Permeability in SARS-cov-2 (COVID-19) Adult respiratory distress syndrome, Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universite de Sherbrooke University Hospital, Angers Canada 2020-10-26 2021-12-01 2021-3862-APEL-COVID, APEL-COVID, NCT04632732 Phase Not Applicable Recruiting 1 13 Months 140 Frédéric Chagnon, MSc, Olivier Lesur, MD PhD 2020-11-23
An observational study to evaluate the pharmacokinetics and safety of lopinavir in COVID-19 patients Coronavirus disease 19 infection, SARS coronavirus infection lopinavir + ritonavir alone HIV protease inhibitor CHU De Nantes France Phase Not Applicable Status not specified 1 12 2020-11-19
Physical Activity and the Risk of COVID-19 Infection and Mortality Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry Wonju Christian Hospital South Korea 2014-01-01 2020-07-31 2020AN0292, NCT04631861 Phase Not Applicable Completed 1 79 Months 132069 Dong-Hyuk Cho 2020-11-23
A retrospective, single-center, case-control, comparative analysis on the safety and efficacy of anti-IL6 tocilizumab in patients with COVID-19 Coronavirus disease 19 infection tocilizumab alone Osped Niguarda Ca Granda Phase Not Applicable Status not specified 0 222 2020-11-19
Sleep and Covid19: Sleep Behavior in Athletes During Home Confinement Due to the Covid-19 Outbreak Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs) Istituto Ortopedico Galeazzi Spa Italy 2020-05-22 2021-02-28 NCT04632615, SLEEP&COVID19, Sleep and Covid19 Phase Not Applicable Recruiting 1 9 Months 230 Jacopo Antonino Vitale, PhD, Stefano Borghi, MSc 2020-11-19
Intravenous Zotatifin in Adults With Mild or Moderate COVID-19 Coronavirus disease 19 infection zotatifin alone Eukaryotic initiation factor 4A-I inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of California San Francisco, eFFECTOR Therapeutics Inc Medpace Inc 2020-11-16 2021-07-01 EFT226-0003, NCT04632381 Phase 1b Clinical Not yet recruiting 0 7 Months 36 Mark Densel, Neil Sankar, MD, MPH, Rhonda Petsch 2020-11-18
COVID-19 - Administration of the SARS-CoV-2-Neutralizing Monoclonal Antibody DZIF-10c (Infusion) Coronavirus disease 19 infection human monoclonal antibody DZIF-10c alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Cologne Boehringer Ingelheim International GmbH Germany 2020-11-23 2021-06-30 NCT04631666, UNI-KOELN-4288 Phase 1/Phase 2 Clinical Not yet recruiting 1 7 Months 69 Florian Klein, Univ.Prof., Gerd Faetkenheuer, Univ.-Prof., Gerd Fätkenheuer, Henning Gruell, Dr. med. 2020-11-19
Recombinant COVID-19 Vaccine (Sf9 cells) Phase II Clinical Trial Coronavirus disease 19 infection, Viral pneumonia SARS-CoV-2 vaccine (Sf9 Cell, COVID-19), Jiangsu Province Centers for Disease Control and Prevention alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Jiangsu Province Centers for Disease Control and Prevention, West China Hospital China 2020-11-17 2021-11-18 ChiCTR2000039994 Phase 2 Clinical Not yet recruiting 1 12 Months 960 Fengcai Zhu, Wei Wang 2020-11-23
Evaluation of respiratory Tele-rehabilitation in patient with COVID-19 Coronavirus disease 19 infection Diaphragmatic breathing exercise alone, Incentive spirometry exercise alone, Seated arm reaches alone, Sit to stand squats alone, Standing heel raises alone, Standing marching alone, Wall pushups alone, respiratory tele-rehabilitation alone, video conferencing program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mashhad University of Medical Sciences Iran 2020-11-21 IR.MUMS.NURSE.REC.1399.052, IRCT20200711048077N1 Phase Not Applicable Recruiting 1 60 Ali khorsand vakilzadeh, Fateme Rangani, Mohsen Tafaghodi 2020-11-23
Psychological effect of COVID 19 on Positive female patient Anxiety disorder, Coronavirus disease 19 infection, Psychiatric disorder Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Medical Sciences Patna India 2020-11-25 CTRI/2020/11/029200 Phase Not Applicable Not yet recruiting 1 25 Dr Poonam Kumari 2020-11-23
A phase III clinical trial of SARS-CoV-2 protein subunit vaccine (COVID-19) in COVID-19 patients Coronavirus disease 19 infection SARS-CoV-2 protein subunit vaccine (COVID-19), Chongqing Zhifei Biological Products/ Institute of Microbiology, Chinese Academy of Sciences alone COVID19 Spike glycoprotein modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Anhui Zhifei Longcom Biopharmaceutical Co Ltd Uzbekistan Phase 3 Clinical Status not specified 1 5000 2020-11-18
An observational study to determine the association of vaccine coverage with the prevalence of SARS-CoV-2 infection Coronavirus disease 19 infection BCG vaccine alone Utano National Hospital Japan Phase Not Applicable Status not specified 1 2020-11-18
A clinical study to assess repurposed niclosamide in the treatment of patients with COVID-19 Coronavirus disease 19 infection repurposed niclosamide (oral/tablet, COVID-19), Hyundai Bioscience/CNPharm alone CNPharm Co Ltd Phase Not Applicable Planned 0 2020-11-18
HERODOTUS: Head and Neck cancers International Covid-19 collaboration Coronavirus disease 19 infection, Head and neck tumor, Nasal cancer, Salivary gland cancer, Thyroid tumor, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hellenic Cooperative Oncology Group Emory University, Fondazione IRCCS Istituto Nazionale Tumori, Grupo Español de Tratamiento de Tumores de Cabeza y Cuello, National Cancer Centre of Singapore, The University of Birmingham, University of Queensland, University of Toronto Greece 2020-12-01 2021-06-30 HERODOTUS, HERODOTUS, NCT04632173 Phase Not Applicable Not yet recruiting 1 7 Months 750 Amanda Psyrri, Amanda Psyrri, MD, Evita Fragou, Lisa Licitra, MD 2020-11-19
NUEVA: BCG Vaccination to Prevent COVID-19 Coronavirus disease 19 infection BCG vaccine, Organon alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Henry M Jackson Foundation for the Advancement of Military Medicine Harvard Medical School, US Department of Defense, Uniformed Services University of the Health Sciences US 2020-11-30 2023-04-30 NCT04632537, NUEVA, USUHS.2020-062 Phase 3 Clinical Not yet recruiting 1 29 Months 550 Dutchabond Shaw, RN, Naomi E Aronson, Thomas G Oliver, Thomas Oliver, MD 2020-11-20
RHEA-COVID19: Effectiveness and Safety of Rhea Health Tone as add-on Therapy for COVID-19 in Hospitalized Adults in Indonesia Coronavirus disease 19 infection Rhea Health Tone alone, Standard of Care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Universitas Padjadjaran PT. Rhea Pharmaceutical Sciences Indonesia, Prodia Clinical Laboratory Indonesia 2020-12-01 2021-02-15 NCT04627519, PHARM-202010.01, RHEA-COVID19 Phase 2 Clinical Not yet recruiting 1 2 Months 69 Haig YH Babikian, Keri Lestari, Keri Lestari, PhD 2020-11-19
High GRP78 Levels in Covid-19 Infection: A Case-Control Study Coronavirus disease 19 infection ELISA kit, Sun Long alone, Serum protein level analysis alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kafkas University Acibadem University, Pamukkale University Faculty of Medicine Turkey 2020-04-16 2020-10-10 CLINICAL-2, NCT04628637 Phase Not Applicable Completed 1 5 Months 144 Ramazan Sbirli, Dr. 2020-11-19
Curaneum 20 for Covid 19 Coronavirus disease 19 infection Curaneum 20 alone, standard management alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) India 2020-12-01 CTRI/2020/11/029166 Phase 3 Clinical Not yet recruiting 1 200 Arunaloke Chakrabarti, Prof Pradip Bhattaharyya 2020-11-20
Study to evaluate the knowledge, attitude and mental health of in-hospital front-line warriors of operation theatre Coronavirus disease 19 infection, Psychiatric disorder Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Government Medical College and Hospital,Chandigarh India 2020-11-20 CTRI/2020/11/029159 Phase Not Applicable Not yet recruiting 1 200 Sukanya Mitra 2020-11-20
Clinical Study Spartan COVID-19 V2 System (Canada Alternate) Coronavirus disease 19 infection Spartan COVID-19 v2 System alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Spartan Bioscience Inc US, Canada 2020-11-30 2021-01-31 NCT04628208, VNV-00635 Phase Not Applicable Not yet recruiting 2 2 Months 60 Tara Linseman 2020-11-19
Covid19-Pain: Musculoskeletal Pain In Patients With COVID-19 Who Have Hospital Care Coronavirus disease 19 infection, Musculoskeletal pain Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fondazione Don Carlo Gnocchi - Onlus Italy 2020-12-01 2021-07-31 COVID19-PAIN, Covid19-Pain, NCT04632355 Phase Not Applicable Not yet recruiting 1 8 Months 100 Jorge H Villafañe, Jorge H Villafañe, Ph.D 2020-11-20
Covid-19 Anxiety And Phobia Levels Of The Parents Anxiety disorder, Coronavirus disease 19 infection, Phobia Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Selcuk University Turkey 2020-05-01 2020-10-15 FARUKCICEKCI, NCT04631172 Phase Not Applicable Completed 1 5 Months 150 Faruk Cicekci 2020-11-20
CMR Findings in COVID-19 Patients Presenting With Myocardial Infarction Coronavirus disease 19 infection, Myocardial infarction cardiac magnetic resonance imaging alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assiut University Egypt 2021-01-01 2023-10-31 CMR IN MYOCARDIAL INFARCTION, NCT04628104 Phase Not Applicable Not yet recruiting 1 34 Months 60 Mohamed Ahmed Abdallah Hamada, hosam hasan, master, mohamed ahmed, Master 2020-11-19
mHealth Intervention for Increasing COVID-19 Prevention Practices With Urban Refugee and Displaced Youth in Uganda Coronavirus disease 19 infection Kukaa Sala mHealth intervention alone, face mask and soap provision alone Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs) University of Toronto Uganda 2021-02-01 2021-09-20 IDRC_COVID, NCT04631367 Phase Not Applicable Not yet recruiting 1 7 Months 404 Carmen H Logie, PhD, Moses Okumu, PhD 2020-11-19
ANCOR: What can the investigators learn from the implementation of a novel point-of-care antigen-based SARS-CoV-2 rapid diagnostic test to screen incoming patients in a large university hospital? (COVID-19) Coronavirus disease 19 infection novel point-of-care antigen-based SARS-CoV-2 rapid diagnostic test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Heidelberg Germany 2020-11-23 ANCOR, DRKS00023584, S-811/2020 Phase Not Applicable Not yet recruiting 1 44 Claudia Denkinger 2020-11-20
Characteristics of COVID-19 Patients in Kazakhstan in Early 2020 Coronavirus disease 19 infection, Respiratory distress syndrome, Sepsis, Septic shock, Viral pneumonia Semey State Medical University Kazakhstan 2020-02-20 2020-12-01 76.29.31_48.04.06-01, NCT04627194 Phase Not Applicable No longer recruiting 1 9 Months 1000 Maiya Goremykina, M.D, C.M.S, Raifa Ivanova, MD, D.M.S., Sergey Yegorov, Ph.D., Yersin Zhunussov, MD, D.M.S. 2020-11-19
Efficacy and safety of pentoxifylline in treatment and recovery of patients with COVID-19 Coronavirus disease 19 infection Variable regimens including hydroxychloroquine , pentoxifylline , sofosbuvir + daclatasvir Phosphoric diester hydrolase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Iran University of Medical Sciences Iran 2020-08-17 IR.IUMS.REC.1399.458, IRCT20170809035597N2 Phase 3 Clinical No longer recruiting 2 86 Azadeh Goodarzi, Azadeh Goodarzi, Simin Almasi 2020-11-20
AntagoBrad-Cov: Evaluation of the effects of bradykinin antagonists on pulmonary manifestations of COVID-19 infections Coronavirus disease 19 infection, Lung disease CE-1145 plus icatibant Bradykinin B2 receptor antagonist, Complement C1s subcomponent inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) GCS Ramsay Santé pour l’Enseignement et la Recherche France 2020-11-12 2020-002225-29, AntagoBrad-Cov, AntagoBrad-Cov Phase 2 Clinical Recruiting 1 45 SAHBANE 2020-11-20
AspCOVID-19 study: Fungal infection of the airways in severe COVID-19 pneumonia Aspergillus infection, Coronavirus disease 19 infection, Viral pneumonia standard laboratory parameters alone, standard microbiological testing alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Technical University of Munich Germany 2020-03-11 2020-07-31 AspCOVID-19 study, ISRCTN14810048 Phase Not Applicable Completed 2 4 Months 32 Dr Lahmer 2020-11-23
Prospective research for early detection of COVID-19 pneumonia using mobile CT vehicle at specialized accommodation facilities Coronavirus disease 19 infection, Viral pneumonia mobile CT vehicle alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Yokohama City University Japan Agency for Medical Research and Development Japan 2020-11-17 UMIN000042477 Phase Not Applicable Recruiting 1 150 Tsuneo Yamashiro 2020-11-19
Japanese health and safety information for international visitors: a randomized controlled trial Coronavirus disease 19 infection sa-chan game alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Human Environments, University of Tokyo Japan Science and Technology Agency North America, Europe, Australia 2020-12-15 UMIN000042483 Phase Not Applicable Not yet recruiting 1 1000 Mariko Nishikawa 2020-11-20
Antiinflammatory and anticoagulative agents in COVID-19 pneumonia treatment Coronavirus disease 19 infection, Viral pneumonia Dexamethasone plus enoxaparin sodium Low molecular weight heparin IM Sechenov Moscow Medical Academy Russian Federation, Europe 2020-04-08 UMIN000042489 Phase Not Applicable Completed 1 157 Petr Tkachenko, Vladimir Ivaashkin 2020-11-19
A retrospective study to analyze the impact of influenza A virus (IAV) exposure on COVID-19 Coronavirus disease 19 infection, Influenza virus A infection oseltamivir alone Exo-alpha sialidase inhibitor Peking University First Hospital China Phase Not Applicable Status not specified 1 70 2020-11-18
Does emergency orthopedic surgery in the pandemic era increase the risk of developing COVID-19? A combined analysis of retrospective and prospective study at a national tertiary hospital in Jakarta, Indonesia Coronavirus disease 19 infection, Surgical procedure orthopedic surgery alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Cipto Mangunkusumo Hospital, University of Indonesia Indonesia, Asia 2020-04-01 UMIN000042453 Phase Not Applicable Completed 2 14 Achmad Kamal, I Wayan Arya Mahendra Karda 2020-11-20
DemStepCare: General practitioner-based dementia care with coordinated cooperation and risk-stratified use of specialized nurses Coronavirus disease 19 infection, Dementia DemStepCare intervention alone Klinikum der Albert-Ludwigs Universitaet Freiburg Dlr Deutsches Zentrum Für Luft- Und Raumfahrt Ev Germany 2019-10-17 2019-14427, DRKS00023560, DemStepCare Phase Not Applicable Recruiting 1 2400 Erik Farin-Glattacker, Teresa Weber 2020-11-20
Clinical profiles and outcomes of COVID patients given with remdesivir: A single centre experience Coronavirus disease 19 infection remdesivir alone COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Southern Philippines Medical Center Philippines 2020-03-01 PHRR201111-003148 Phase Not Applicable Not yet recruiting 1 Ranillo V Gamutan Jr 2020-11-20
Sero-surveillance for Dengue, Chikungunya and COVID Chikungunya virus infection, Coronavirus disease 19 infection, Dengue virus infection Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) International Clinical Epidemiology Network (INCLEN) TRUST India 2020-12-01 CTRI/2020/11/029141 Phase Not Applicable Not yet recruiting 1 5000 Divya Nair, Shikha Dixit 2020-11-20
Role of Heparin inhalation in reducing the duration the patient is breathing with the help of a ventilator Coronavirus disease 19 infection Heparin alone, Standard care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Medical Sciences Patna India 2020-12-01 CTRI/2020/11/029175 Phase 2 Clinical Not yet recruiting 1 58 Shagufta Naaz 2020-11-19
Validation of immune booster potential of Kabasura Kudineer Coronavirus disease 19 infection Kabasura Kudineer alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Central Council for Research in Siddha, Ministry of Ayush India 2020-11-18 CTRI/2020/11/029137 Phase Not Applicable Not yet recruiting 1 100 Dr Aiswarya M Nair, Dr Parameswari RP, Prof SP Thyagarajan 2020-11-19
Difficulties encountered with respiration while providing analgesia for surgeries to patients who had recovered from Covid-19 infection Coronavirus disease 19 infection, General anesthesia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) SRM University India 2020-11-20 CTRI/2020/11/029148 Phase Not Applicable Not yet recruiting 1 50 Dr CR Saravanan, Dr Parameshwaran M 2020-11-19
Use of a new breathing device for covid 19 patients Coronavirus disease 19 infection InVicto alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Royal Brompton Hospital India 2020-11-23 CTRI/2020/11/029146 Phase Not Applicable Not yet recruiting 1 240 Dr Alben Sigamani, Dr Vimal Bharadwaj 2020-11-19
Impact of COVID 19 on Guillain-Barre Syndrome in India Coronavirus disease 19 infection, Guillain Barre syndrome Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences India 2020-12-01 CTRI/2020/11/029143 Phase Not Applicable Not yet recruiting 1 300 Vishnu VY 2020-11-20
Effect of Covid19 work from home on musculoskeletal disorders Coronavirus disease 19 infection, Musculoskeletal disease Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Manipal Academy of Higher Education India 2020-12-01 CTRI/2020/11/029142 Phase Not Applicable Not yet recruiting 1 498 Dr G Arun Maiya, Garima Gupta 2020-11-19
The effects of aromatherapy on the anxiety and sleep quality of the patients with COVID-19 Anxiety disorder, Coronavirus disease 19 infection aromatherapy alone, lavender essential oil (Zardband company) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Kerman University of Medical Sciences Iran 2020-11-05 IR.KMU.REC.1399.423, IRCT20201020049088N1 Phase 2 Clinical Recruiting 1 60 Abbas Pardakhti, Behnaz Bagherian, Mohammad Hossein Mehrolhassani 2020-11-20
TS-COVID: Prevention With Chloroquine in Health Personnel Exposed to Infection With Coronavirus Disease 2019 (COVID-19) Coronavirus disease 19 infection chloroquine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundacion Clinica Valle del Lili Colombia 2020-03-28 2021-02-14 FVL-1567, NCT04627467, TS-COVID Phase 2 Clinical No longer recruiting 1 10 Months 3217 Juan D Velez, MD 2020-11-19
Baseline Vitamin D Deficiency and COVID-19 Disease Severity Coronavirus disease 19 infection, Vitamin D deficiency Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Parkview Medical Center US 2020-10-27 2022-04-14 NCT04628000, PIRB78 Phase Not Applicable Recruiting 1 17 Months 50 Doug Duffee, Doug Duffee, MD, Stephaine Lucas, MD, Stephanie Lucas, MD 2020-11-18
Mothers view on the impact of increased screen time on the overall health of school going children during COVID-19 Coronavirus disease 19 infection survey alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Welcomgroup Graduate School of Hotel Administration India 2020-11-22 CTRI/2020/11/029171 Phase Not Applicable Not yet recruiting 1 261 Humaira Fatima Shah, Mrs Swathi Acharya K 2020-11-18
Efficacy of Yoga Based Self-Management Program for Chronic Pain Coronavirus disease 19 infection, Pain Yoga based self-management alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Aarogyam UK Patanjali Yog Peeth (UK) Trust UK 2020-09-17 2020-11-09 AU0211, NCT04628130 Phase Not Applicable Completed 2 1 Month 42 Deepa Modi, Neha Sharma, Sunita Poddar, Vishwesh Kulkarni 2020-11-18
A phase I/Ii clinical trial of PDS-0203 for the potential prevention of COVID-19 infection Coronavirus disease 19 infection PDS-0203 alone Coronavirus spike glycoprotein inhibitor PDS Biotechnology Corp 2021-06-30 Phase 1/Phase 2 Clinical Planned 0 2020-11-17
Covid19 Antibody prevalence and sustainability. A retrospective, longitudinal, mono-centered, observational study in Covid-19 PCR positive hospital workers Coronavirus disease 19 infection Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ernst von Bergmann Clinic Germany 2020-11-20 DRKS00023561, S 30(bB)/2020 Phase Not Applicable Recruiting 1 207 Maria Biersack 2020-11-18
Comparison of the Surgical Facemask With the Double-trunk Mask on Oxygenation in COVID-19 Coronavirus disease 19 infection Double-Trunk Mask alone, Surgical Mask alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Clinique Universitaires Saint-Luc Belgium 2020-11-13 2021-11-13 DTM-003, NCT04629989 Phase Not Applicable Recruiting 1 12 Months 27 William Poncin, William Poncin, PT, PhD 2020-11-20
A Smartphone Intervention for Relational and Mental Well Being Coronavirus disease 19 infection, Depression daily text messages alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Washington US 2020-04-04 2020-08-03 NCT04629755, STUDY00009897 Phase Not Applicable Completed 1 4 Months 1765 Jonathan W Kanter, PhD 2020-11-21
A case-control study to assess safety and efficacy of lenzilumab in the treatment of patients with severe COVID-19 and acute respiratory distress syndrome (ARDS) Coronavirus disease 19 infection, Respiratory distress syndrome lenzilumab alone GM-CSF ligand inhibitor, Immunoglobulin G1 modulator, Immunoglobulin kappa modulator Humanigen Inc US Phase Not Applicable Status not specified 1 39 2020-11-17
LAUREL: Chronic Lung Disease and COVID-19: Understanding Severity, Recovery and Rehabilitation Needs Coronavirus disease 19 infection Rehabilitation-focused program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) VA Office of Research and Development US 2021-11-01 2024-10-31 1 I01 RX-003666-01, F3666-R, LAUREL, NCT04628039 Phase Not Applicable Not yet recruiting 1 36 Months 506 John R Kundzins, BS, Kristina A Crothers, MD 2020-11-20
General Psychological Distress, PTSD, and Co-Morbidities in Healthcare Workers Consequent to COVID-19 Acute stress disorder, Coronavirus disease 19 infection, Post traumatic stress disorder Interpersonal Psychotherapy alone, Medical Music alone, Narrative Writing alone, Prolonged Exposure Therapy alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Weill Medical College of Cornell University US 2020-11-30 2021-09-30 20-04021913, NCT04626050 Phase Not Applicable Not yet recruiting 1 10 Months 120 JoAnn Difede, PhD, Mariel Emrich, BS 2020-11-20
PASSION: Proximal Effects of Alcohol on Same-Sex Intimate Partner Violence Acute stress disorder, Coronavirus disease 19 infection CBT Text Messaging alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Georgia State University University at Buffalo US 2020-11-30 2022-09-30 NCT04625465, PASSION, R01AA025995 Phase Not Applicable Recruiting 1 22 Months 480 Dominic J Parrott, Ph.D., Konrad Bresin, Ph.D. 2020-11-19
M3Epilepsy: Making Mindfulness Matter in Children With Epilepsy Coronavirus disease 19 infection, Epilepsy Making Mindfulness Matter (M3) alone Preschool Children (2-5 yrs), Children (6-12 yrs) Lawson Health Research Institute Canadian Institutes of Health Research Canada 2019-12-02 2022-12-20 6558, M3Epilepsy, NCT04020484 Phase Not Applicable Recruiting 1 36 Months 100 Karen Bax, Ph.D., Kathy Nixon Speechley, Ph.D, Kathy Nixon Speechley, Ph.D., Mary Secco, MSc cand. 2020-11-21
Effect of the globally spread Covid-19 on the diet and lifestyle of adults (25 to 60 years) Coronavirus disease 19 infection questionnaire alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Welcomgroup Graduate School of Hotel Administration India 2020-11-23 CTRI/2020/11/029172 Phase Not Applicable Not yet recruiting 1 200 Deeksha Lobo, Jasmine Tamak, Mrs Pallavi Mahesh Shettigar 2020-11-20
What does Covid 19 do to patients with long standing Kidney disease and the impact of treatment on their course in hospital - a tertiary care hospital study Coronavirus disease 19 infection, End stage renal disease hemodialysis alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kasturba Medical College India 2020-12-01 CTRI/2020/11/029173 Phase Not Applicable Not yet recruiting 1 62 Dr B A SHASTRY, MAHAD HASAN KHAN 2020-11-21
Impact of COVID 19 on domestic responsibilities in physicians Coronavirus disease 19 infection questionnaire alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tata Memorial Hospital India 2020-11-30 CTRI/2020/11/029174 Phase Not Applicable Not yet recruiting 1 2000 Sabita Jiwnani 2020-11-19
Lignocaine nebulization in covid pneumonia Coronavirus disease 19 infection, Viral pneumonia lignocaine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute Of Medical Sciences, Rishikesh India 2020-11-20 CTRI/2020/11/029170 Phase 2 Clinical Not yet recruiting 1 60 Dr Praveen Talawar 2020-11-20
A phase II clinical study to assess STI-2099 either as a stand-alone nasal application or as a combination nasal and intravenous administration in both mild and moderate COVID-19 patients Coronavirus disease 19 infection STI-2099 alone Sorrento Therapeutics Inc Phase 2 Clinical Planned 0 2020-11-17
A phase I safety and pharmacokinetic study of STI-2099 in healthy subjects and outpatients with mild COVID-19 disease with or without a simultaneous intravenous injection of COVI-AMG Coronavirus disease 19 infection STI-2099 alone, COVI-AMG plus STI-2099 COVID19 Spike glycoprotein inhibitor Healthy volunteers accepted Sorrento Therapeutics Inc Phase 1 Clinical Planned 0 2020-11-17
A Phase II Clinical Trial of MW-33 Injection in Patients With COVID-19 Coronavirus disease 19 infection MW-33 alone COVID19 Spike glycoprotein inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mabwell (Shanghai) Bioscience Co Ltd 2020-11-30 2021-09-30 MW33-2020-CP201, NCT04627584 Phase 2 Clinical Not yet recruiting 0 10 Months 150 Bei ZHAO, Master, Song LU, Master 2020-11-18
Echo-COVID: Cardiac Performance in Mechanically Ventilated COVID-19 Patients Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia Mindray M9 (Bio-Medical Electronics Co) alone, Philips CX 50 (Philips Healthcare) alone, Vivid i echocardiography system (GE Medical Systems) alone, echocardiography alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Pontificia Universidad Catolica De Chile Clinica Alemana de Santiago, Hospital Barros Luco Trudeau, University of Chile Chile 2020-04-01 2020-08-01 200422002, Echo-COVID, NCT04628195 Phase Not Applicable Completed 1 4 Months 100 Emilio Valenzuela, M.D 2020-11-18
Expanded Evaluation of the Survivorship Wellness Group Program in the Context of COVID-19 and Telehealth Anxiety disorder, Coronavirus disease 19 infection, Depression Survivorship Wellness Group Program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of California San Francisco US 2020-08-31 2023-12-31 20805, NCI-2020-08530, NCT04630015 Phase Not Applicable Recruiting 1 40 Months 250 Alison Chang, Diane Shumay, PhD, Margaret Chesney, MD, Margaret Chesney, PhD, cancertrials@ucsf.edu 2020-11-19
A retrospective cohort study to examine outcomes among patients who were treated anakinra or tocilizumab for COVID-19 -related cytokine storm Coronavirus disease 19 infection anakinra alone, tocilizumab alone Type I IL-1 receptor antagonist University of California Los Angeles US Phase Not Applicable Status not specified 1 93 2020-11-17
Face Masks to Reduce COVID-19 in Bangladesh Coronavirus disease 19 infection Face mask alone, face mask awareness alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Yale University Innovation for poverty action, North South University, Stanford University Bangladesh 2020-11-15 2021-02-28 2000028482, NCT04630054 Phase Not Applicable Recruiting 1 3 Months 450000 Jason Abaluck, PhD, Md. Alamgir Kabir, BA, Mohammad Ashraful Haque, BA, Stephen P Luby, MD 2020-11-19
Effect of Covid-19 on Outcomes of Pregnancy Coronavirus disease 19 infection PCR test alone Healthy volunteers accepted, Female, Young Adults (18-44 yrs) Assiut University Egypt 2020-09-01 2021-12-01 12789, NCT04629001 Phase Not Applicable No longer recruiting 1 15 Months 1000 Armia Michael 2020-11-19
A real-world study to evaluate T-Detect COVID for past infection Coronavirus disease 19 infection T-Detect COVID alone Adaptive Biotechnologies Corp Ospedale San Raffaele, University of Padua Italy Phase Not Applicable Status not specified 1 2020-11-19
COVID-19 Infection Rate in the Construction- and Cleaning Industry Coronavirus disease 19 infection Spirometry alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Arbeitsmedizinischer Dienst der BG BAU GmbH Berufsgenossenschaft der Bauwirtschaft Germany 2020-11-22 BO/40/2020, DRKS00023558 Phase Not Applicable Not yet recruiting 1 3000 Thomas Solbach 2020-11-20
A retrospective case-control study to evaluate the impact of tocilizumab on mortality and/or invasive mechanical ventilation requirement in a cohort COVID-19 patients Coronavirus disease 19 infection Invasive mechanical ventilation alone, tocilizumab alone Hôpital Nord Franche-Comté France Phase Not Applicable Status not specified 1 206 2020-11-17
Verification of stress relief by introducing online visits to the restrictions on visits of COVID-19 Acute stress disorder, Coronavirus disease 19 infection online visit alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Jinseikai Kohnan Hospital Japan 2020-11-16 UMIN000042384 Phase Not Applicable Not yet recruiting 1 100 Hiroshi Yamamoto 2020-11-18
Maternal Attachment and Depression Anxiety Score Evaluation in COVID-19 Positive Pregnant Women Anxiety disorder, Coronavirus disease 19 infection, Depression Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Istanbul Bakirkoy Maternity and Children Diseases Hospital Turkey 2020-08-01 2020-11-20 MATERNALATTACHMENTCOVID, NCT04629638 Phase Not Applicable No longer recruiting 1 3 Months 500 Pınar Yalcin bahat 2020-11-21
RECOVER: Regenerative Medicine for COVID-19 and Flu-Elicited ARDS Using Longeveron Mesenchymal Stem Cells (LMSCs) Adult respiratory distress syndrome, Coronavirus disease 19 infection, Influenza virus infection allogeneic human mesenchymal stem cells (aging frailty/Alzheimer's disease/metabolic syndrome/hypoplastic left heart syndrome), Longeveron alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Longeveron LLC US 2020-07-24 2025-07-31 00-006, NCT04629105, RECOVER Phase 1 Clinical Recruiting 3 60 Months 70 Andrew Quartin, MD, Anthony Oliva, PhD, Carl Shanholtz, MD, Freshta Akbari, MS, Gisel Urdaneta, MD, John P Galliard, MD, Kevin N Ramdas, MD, MPH, Kristopher Deatrick, MD, Mary- Clare Day, RN, BSN, CCRC, Roland Schein, MD, Sunjay Kaushal, MD, PhD 2020-11-20
CODED: Risk Stratification of COVID-19 Patients Discharged From the Emergency Department Coronavirus disease 19 infection chest radiography alone, lung ultrasonosgraphy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Azienda Ospedaliera Citta della Salute e della Scienza di Torino University of Turin Italy 2020-11-01 2021-07-31 CODED, COVID-ED-INTRISK, NCT04629183 Phase Not Applicable Recruiting 5 9 Months 400 Emanuele E Pivetta, MD, PhD, Enrico Lupia, MD, PhD, Franco Aprà, MD, Fulvio Morello, MD, PhD, Giuseppe Lauria, MD, Peiman Nazerian, MD, Stefano Podio, MD 2020-11-19
LAVA: The LAVA (Lateral Flow Antigen Validation and Applicability) Study for COVID-19 Coronavirus disease 19 infection Innova Lateral Flow Device alone, RT-PCR alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) Alder Hey Children's NHS Foundation Trust UK 2020-11-05 2020-11-19 290989, LAVA, NCT04629157 Phase Not Applicable Recruiting 2 400 Beatriz Larru, MD, Christopher Kelly, Laura Rad, Lucy Cooper, Rachel Harwood, MB BS, Richard Kirk 2020-11-19
Evaluation of a new adhesive system for orthodontic braces for a 6-month period Coronavirus disease 19 infection, Tooth disease conventional bracket system (CS) alone, flash-free adhesive system alone, pre-coated bracket system (PS) alone Ondokuz Mayis University Turkey 2018-06-08 2019-06-18 ISRCTN26731749, OMÜ KAEK 2018/416 Phase Not Applicable Completed 2 12 Months 30 Prof Elekdag-Turk 2020-11-20
A phase II trial of BNT-162b2 for the treatment of COVID-19 Coronavirus disease 19 infection BNT-162b2 alone COVID19 Spike glycoprotein modulator Shanghai Fosun Pharmaceutical (Group) Co Ltd China Phase 2 Clinical Not yet recruiting 1 2020-11-17
Double-Blind, Randomized, Placebo-Controlled, Adaptive-Design, Multicenter, Phase III Study to Evaluate the Efficacy and Safety of Fostamatinib in COVID-19 Subjects Coronavirus disease 19 infection fostamatinib disodium alone, standard of care alone Syk tyrosine kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rigel Pharmaceuticals Inc 2020-12-31 2021-08-31 C-935788-061, NCT04629703 Phase 3 Clinical Not yet recruiting 0 8 Months 308 2020-11-18
EST-OBS-OZO-BIOPLA-SARS-COV 2: Observational study benefits rectal ozone therapy and BIOPLA as complementary therapy in convalescent patients SARS-COV-2 Coronavirus disease 19 infection BIOPLA alone, rectal ozone therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Center for Scientific Research, Cuba BioCubaFarma Cuba 2020-06-08 2020-08-15 EST-OBS-OZO-BIOPLA-SARS-COV 2, RPCEC00000342 Phase Not Applicable No longer recruiting 1 2 Months 40 Mario Slim War, Zullyt Zamora Rodriguez 2020-11-20
A clinical trial to evaluate the safety and pharmacokinetics of COVI-AMG in healthy subjects Coronavirus disease 19 infection COVI-AMG alone COVID19 Spike glycoprotein inhibitor Healthy volunteers accepted Sorrento Therapeutics Inc US Phase Not Applicable Not yet recruiting 1 2020-11-17
A retrospective study of zinc sulfate in combination with a zinc ionophore may improve outcomes in hospialized COVID-19 patients Coronavirus disease 19 infection Variable regimens including azithromycin , hydroxychloroquine , zinc sulphate New York University School of Medicine, US US Phase Not Applicable Status not specified 1 932 2020-11-17
Tracheobronchitis in Respiratory Involvement on the Lung SPECT/CT Images of COVID-19 Patients Coronavirus disease 19 infection, Dyspnea, Tracheobronchitis perfusion lung scintigraphy alone, ventilation alone Central Hospital, Nancy, France France 2020-03-11 2020-07-23 2020PI154, NCT04629222 Phase Not Applicable Completed 1 4 Months 10 Pierre Yves MARIE, PhD 2020-11-18
Clinical trial to evaluate superiority of anti-SARS-CoV-2 convalescent plasma versus standard-of-care in hospitalized patients with mild COVID-19 Coronavirus disease 19 infection Fresh frozen plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hannover Medical School German Federal Ministry of Health Germany 2020-10-19 2020-001936-86, COMET Phase 2 Clinical Recruiting 1 340 Institute of Transfusion Medicine 2020-11-20
A retrospective study of machine learning models that predict the likelihood of critical events and mortality in COVID-19 patients within clinically relevant time windows Coronavirus disease 19 infection machine learning model alone Mount Sinai School of Medicine US Phase Not Applicable Status not specified 1 4000 Benjamin Glicksberg 2020-11-18
NOTICE: A retrospective chart review study,to collect real-world data on the use of Inomax (nitric oxide) gas, for inhalation therapy in patients with respiratory complications associated with the novel coronavirus SARS-CoV-2 (COVID-19) Coronavirus disease 19 infection, Hypoxia, Respiratory disease nitric oxide (inhaled), Ikaria alone Hemoglobin modulator Mallinckrodt plc Pharmerit International NOTICE Phase 4 Clinical Status not specified 0 2020-11-16
IPCO: Prospective, open-label, randomized, controlled, phase IIb clinical study in parallel groups for the assessment of efficacy and safety of immune therapy with COVID-19 convalescent plasma plus standard treatment versus standard treatment alone of subjects with severe COVID-19 Coronavirus disease 19 infection convalescent plasma alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitatsklinikum Erlangen Germany 2020-06-12 2020-002122-82, IPCO, UKER-COV2-01 Phase 2b Clinical Recruiting 1 58 Transfusionsmedizinische Abteilung 2020-11-18
The lying in prone position effect on oxygen saturation in patients in early stage and not intubated having mild to moderate Lung Disease with COVID-19 Coronavirus disease 19 infection, Lung disease, Respiratory distress syndrome, Viral pneumonia Prone positionioning alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Medical Sciences Patna India 2020-11-16 CTRI/2020/11/029130 Phase Not Applicable Not yet recruiting 1 48 Shagufta Naaz 2020-11-20
A retrospective observational cohort study of clinical characteristics and predictors of survival in adults with coronavirus disease 2019 receiving tocilizumab Coronavirus disease 19 infection tocilizumab alone Henry Ford Health System US Phase Not Applicable Status not specified 1 81 2020-11-17
Effect of COVID-19 on exercise pattern, diet pattern and weight change in athletes Coronavirus disease 19 infection questionnaire alone Healthy volunteers accepted, Young Adults (18-44 yrs) Welcomgroup Graduate School of Hotel Administration India 2020-11-21 CTRI/2020/11/029124 Phase Not Applicable Not yet recruiting 1 336 Rachana, Swathi Acharya 2020-11-18
Covid-19 risk factors among health care workers Coronavirus disease 19 infection Hydroxychloroquine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Kasturba Medical College India 2020-11-21 CTRI/2020/11/029084 Phase Not Applicable Not yet recruiting 1 172 Cynthia Amrutha Sukumar 2020-11-20
A prospective study on the interobserver variability of COVID-19 Reporting and Data System (CO-RADS) among radiologists in the Philippine General Hospital Coronavirus disease 19 infection CO-RADS alone Philippine General Hospital, University of the Philippines Philippines 2020-08-01 2020-11-10 PHRR201116-003153 Phase Not Applicable Completed 1 3 Months Gerard Eastdon Ochoco 2020-11-17
Characteristics, Risk Factors, and Clinical outcomes of Confirmed Adult COVID Cases admitted in the Intensive Care Unit of Southern Philippines Medical Center from March to December 2020 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Southern Philippines Medical Center Philippines 2020-03-01 2021-12-31 PHRR201116-003143 Phase Not Applicable Not yet recruiting 1 22 Months Dorothy Joy Edulan Bacomo, Jonathan Jasper Ortiz Barnachea 2020-11-20
The Largest Cluster of Covid-19 in Jerantut Coronavirus disease 19 infection Jabatan Kesihatan Negeri Pahang Malaysia 2020-11-05 2020-12-01 57119, NMRR-20-2448-57119 Phase Not Applicable Status not specified 1 Dr ATIRAH BINTI MOHD AZIZUL 2020-11-17
A clinical trial of AT-301 (nasal spray, COVID-19), Atossa Therapeutics for the treatment of covid-9 infection Coronavirus disease 19 infection AT-301 (nasal spray, COVID-19), Atossa Therapeutics alone COVID19 Spike glycoprotein inhibitor Atossa Therapeutics Inc Phase 2 Clinical Planned 0 2020-11-16
A study to evaluate the impact of COVID-19 on patients with cystic fibrosis Coronavirus disease 19 infection, Cystic fibrosis Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Cystic Fibrosis Foundation South Africa, Australia, Chile, France, Canada, New Zealand, Russian Federation, US, Switzerland, Ireland, Sweden, Belgium, Germany, Spain, Netherlands, UK, Italy, Argentina, Brazil Phase Not Applicable Status not specified 19 181 2020-11-17
HCW-Wristband: Colour-Coded Wristband to Monitor COVID-19 Exposure Status for Healthcare Workers On Early Return to Work After a COVID-19 close contact: A Pilot Study Coronavirus disease 19 infection coloured wristband alone Healthy volunteers accepted HOSPITAL QUEEN ELIZABETH II Malaysia 2020-11-30 2021-06-30 56966, HCW-Wristband, NMRR-20-2443-56966 Phase Not Applicable Status not specified 1 7 Months Dr Teoh Eu Vin, Dr. Liew Houng Bang 2020-11-18
Clinical characteristics and outcomes of ventilated COVID-19 patients in Sungai Buloh Hospital Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Sungai Buloh Malaysia 2020-12-01 2021-02-27 54853, NMRR-20-2441-54853 Phase Not Applicable Recruiting 1 2 Months 50 Dr Nor Haliza Binti Zainol Abidin 2020-11-17
To study the Influence of Food habits, Physical activity and knowledge of pregnant mothers on the problems faced in pregnancy, type of delivery and Birth weight of newborn during COVID-19 times Coronavirus disease 19 infection, Pregnancy disorder telephonic counselling alone Female, Young Adults (18-44 yrs) Welcomgroup Graduate School of Hotel Administration India 2020-11-20 CTRI/2020/11/029070 Phase Not Applicable Not yet recruiting 1 300 Anuhitha Paruchuri, Dr Meenakshi Garg, Rasmiya 2020-11-17
Study of heart injury by laboratory investigation in corona positive patients Coronavirus disease 19 infection, Heart injury Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Sardar Vallabh Bhai Patel Hospital India 2020-11-17 CTRI/2020/11/029068 Phase Not Applicable Not yet recruiting 1 200 Dr Vijaysinh Parmar 2020-11-18
A study to look out outcomes of treated COVID-19 patients admitted to a private hospital in Bangalore Coronavirus disease 19 infection, Renal injury Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Columbia Asia India 2020-11-15 CTRI/2020/11/029067 Phase Not Applicable Not yet recruiting 1 100 Girish Namagondlu 2020-11-19
A Case series, retrospective cohort study of experience with tocilizumab in severe COVID-19 pneumonia after 80 days of follow Coronavirus disease 19 infection, Pneumonia tocilizumab alone Hospital General Universitario De Alicante Spain Phase Not Applicable Status not specified 1 236 2020-11-19
LungCOVID: One year follow-ups of Chilean patients with COVID-19 Coronavirus disease 19 infection, Lung injury, Viral pneumonia blood test alone, chest scan alone, lung function test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidad de Concepcion Agencia Nacional de Investigacion y Desarrollo, Chilean government Chile 2020-09-11 2021-07-30 COVID1005, ISRCTN16865246, LungCOVID Phase Not Applicable Recruiting 2 10 Months 250 Dr Daniel Enos, Dr Gonzalo Labarca, Dr Jaime Lastra, Prof Nova-Lamperti 2020-11-19
RECAP: Assessing patients' risk of COVID-19 severe infection: developing a risk prediction score Coronavirus disease 19 infection Covid-19 templates in EMIS and SystmOne alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Imperial College London Economic and Social Research Council, NIHR Imperial Biomedical Research Centre, NIHR Oxford Biomedical Research Center UK 2020-05-15 2021-04-01 IRAS 283024, CPMS 45890, ISRCTN13953727, RECAP Phase Not Applicable Recruiting 3 10 Months 2870 Dr BelenEspinosaGonzalez 2020-11-19
RECOVERY: A clinical trial of Aspirin for the treatment of blood clots in people with COVID-19 Coronavirus disease 19 infection aspirin alone, standard of care alone Nuffield Department of Population Health UK RECOVERY Phase Not Applicable Status not specified 1 2000 Martin Landray, Peter Horby 2020-11-17
SOVEREIGN 01A: Phase I, randomized, double-blind and adaptive study to evaluate the safety, reactogenicity and explore the immunogenicity of different formulations of the Prophylactic Vaccine Candidates against SARS-CoV-2, FINLAY-FR-1 and FINLAY-FR-1A (COVID-19) Coronavirus disease 19 infection FINLAY-FR-1 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Finlay Institute Cuba 2020-10-19 2021-01-31 IFV / COR / 05, RPCEC00000338, SOVEREIGN 01A Phase 1 Clinical Recruiting 1 3 Months 60 Beatriz Moreno Walls, Meiby Rodriguez Gonzalez, Sonia Perez Rodriguez 2020-11-19
An accelerated design, combined, prospective ascending single-dose and two-dose, randomized, placebo-controlled, blinded, first-in-human adaptive study in healthy adults and patients with COVID-19 infection, to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of therapeutic antibody AOD01 Coronavirus disease 19 infection AOD01 alone Healthy volunteers accepted DSO National Laboratories Singapore AOD01-01 Phase 1/Phase 2 Clinical Planned 1 Dr Brendon Hanson, Dr David Lye Chian Boon 2020-11-20
The efficacy and safety of systemic anticoagulation in novel coronavirus pneumonia (COVID-19): A medical records based retrospective cohort study Coronavirus disease 19 infection, Viral pneumonia systemic anticoagulation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tongji Hospital, Huazhong University of Science and Technology China 2020-09-01 2022-08-31 ChiCTR2000039855 Phase Not Applicable Not yet recruiting 1 24 Months 750 Bian Yi 2020-11-17
A Descriptive Study on the Knowledge, Perceptions, Preferences and Challenges of OBGYNE Surgeons in Using Personal Protective Equipment for COVID-19 Precaution in the Operating Room Coronavirus disease 19 infection Healthy volunteers accepted Philippine General Hospital Philippines 2020-08-24 2020-09-05 PHRR201021-003052 Phase Not Applicable Completed 1 Judith Faye M. Montero 2020-11-19
Correlation of CT severity scoring with clinical classification of disease in COVID-19 positive patients Coronavirus disease 19 infection University of the Philippines Philippines 2020-05-01 2020-08-12 PHRR201021-003070 Phase Not Applicable Completed 1 3 Months Clare Toledo 2020-11-19
MEMORY-COVID: Manganese-Enhanced Magnetic Resonance Imaging of Myocardial injury in COVID-19 Coronavirus disease 19 infection, Heart injury, Myocardial disease, Myocarditis, Systolic dysfunction computed tomography coronary angiography alone, electrocardiography alone, magnetic resonance imaging alone, gadolinium plus manganese Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Edinburgh UK 2020-06-10 2022-06-10 20/NW/0249, MEMORY-COVID, NCT04625075 Phase Not Applicable Recruiting 1 24 Months 40 Shruti Joshi, MBBS, Trisha Singh, BM, Trisha Singh, BM, BMedSci 2020-11-18
PPEDiC: A study of parents views and motivations on presenting to their local pediatric emergency department during the coronavirus pandemic (COVID-19) Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) University Hospital Lewisham UK 2020-05-04 2020-12-31 IRAS 287536, ISRCTN12833010, PPEDiC Phase Not Applicable Not yet recruiting 3 7 Months 220 Dr Nyirenda, Dr Tina Sajjanhaar 2020-11-18
The effect of balloon-blowing on dyspnea and oxygenation in non-critical adult covid-19 patients Coronavirus disease 19 infection, Dyspnea balloon blowing alone, necessary medication alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Qazvin University Of Medical Sciences Iran 2020-07-22 2020-10-30 IR.QUMS.REC.1399.043, IRCT20201012049010N1 Phase Not Applicable Completed 1 3 Months 90 Mohammad Bargahi, Mohammadali emamjomeh, Seyed Saeed Farzam 2020-11-17
OZO-EST-OBS: Prevalence of positive evolutive PCR in patients with COVID 19 treated with rectal ozone therapy: observational study prospective cohort Coronavirus disease 19 infection Ozone therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Center for Scientific Research, Cuba Cuba 2020-08-15 2020-10-25 OZO-EST-OBS, OZO-EST-OBS-01, RPCEC00000341 Phase Not Applicable Completed 1 2 Months 200 Zullyt Zamora Rodriguez 2020-11-17
An Investigation of the impact of Faramir on the clinical symptoms in patients with COVID-19 Coronavirus disease 19 infection faramir containing Salvia officinalis extract (Meem Pharmaceutical Factory) alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Shaheed Beheshti Medical University Iran 2020-11-21 IR.SBMU.MSP.REC.1399.396, IRCT20170315033086N7 Phase 2 Clinical Recruiting 1 128 Minoosh Shabani, Saeed Karima, Somayeh Mahmoodi Baram 2020-11-23
ACCURATE-BL-COVID-19: COVID-19 in Baselland: Validation of Simple and Accurate Tests for COVID-19 Detection, Monitoring and Tracing Coronavirus disease 19 infection LAMP assay alone, NGS diagnostic assay alone, POCT antigen tests alone, crude RNA extraction alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Basel ETH Zurich, Kanton Basel- Landschaft Switzerland 2020-10-24 2021-03-31 2020-01112, ACCURATE-BL-COVID-19, CH20SAVIC2, NCT04625257 Phase Not Applicable Recruiting 1 5 Months 3000 Miodrag Savic, Dr. med. Dr. med. dent. 2020-11-19
SOBERANA 02: Phase I study, open, sequential and adaptive for evaluating the safety, reactogenicity and explore the immunogenicity of the prophylactic Vaccine Candidate FINLAY-FR-2 anti SARS-CoV-2 (COVID-19) Coronavirus disease 19 infection FINLAY-FR-2 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Finlay Institute Cuba 2020-11-02 2021-06-01 IFV/COR/06, RPCEC00000340, SOBERANA 02 Phase 1 Clinical Not yet recruiting 1 7 Months 40 Beatriz, Maria Toledo Romani, Meiby Rodriguez Gonzalez 2020-11-23
MSC-COVID19: Efficacy of Infusions of MSC From Wharton Jelly in the SARS-Cov-2 (COVID-19) Related Acute Respiratory Distress Syndrome Coronavirus disease 19 infection, Multiple organ failure, Respiratory distress syndrome Wharton's jelly mesenchymal stem cells alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Hospital, Nancy, France France 2020-11-06 2022-08-06 2020-002772-12, MSC-COVID19, NCT04625738 Phase 2a Clinical Not yet recruiting 1 21 Months 30 Bruno LEVY, MD, PhD, Cecile POCHON, MD, POCHON Cecile, Sebastien GIBOT, MD, PhD, Sébastien GIBOT, MD, PhD 2020-11-18
PROVENT: Phase III, Double-blind, Placebo-controlled Study of AZD-7442 for Pre-exposure Prophylaxis of COVID-19 in Adult Coronavirus disease 19 infection AZD-7442 alone COVID19 Spike glycoprotein inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) AstraZeneca plc Biomedical Advanced Research and Development Authority (BARDA), IQVIA Holdings Inc UK, US 2020-11-17 2021-12-14 D8850C00002, NCT04625725, PROVENT Phase 3 Clinical Not yet recruiting 2 12 Months 5000 AstraZeneca Clinical Study Information Center, Myron Levin, MD 2020-11-18
DMMETCOV19: Metformin Glycinate in Patients With MS or DM2, Hospitalized With COVID-19 and SARS Secondary to SARS-CoV-2 Coronavirus disease 19 infection, Metabolic syndrome X, Non-insulin dependent diabetes metformin glycinate (diabetes/acute respiratory distress syndrome/COVID-19), Laboratorios Silanes alone, standard treatment alone AMP activated protein kinase stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Laboratorios Silanes SA De CV Mexico 2020-11-30 2021-03-31 DMMETCOV19, NCT04626089, SIL-30000-II(1) Phase 3b Clinical Not yet recruiting 1 4 Months 20 Daniel Juarez, BPC, Fausto González-Villagrán, MD, Jorge Gonzalez-Canudas, MD, Nayeli Goreti, Yulia Romero-Antonio, B.S. 2020-11-18
DMMETCOV19-2: Metformin Glycinate, Treatment of Patients With COVID-19 and Severe Acute Respiratory Syndrome Secondary to SARS-CoV-2 Coronavirus disease 19 infection metformin glycinate (diabetes/acute respiratory distress syndrome/COVID-19), Laboratorios Silanes alone, standard treatment alone AMP activated protein kinase stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Laboratorios Silanes SA De CV Mexico 2020-07-14 2021-03-31 DMMETCOV19-2, NCT04625985, SIL-30000-II-20(2) Phase 3b Clinical Recruiting 1 8 Months 20 Janet S Aguirre, MD, Janet Silvia M Aguirre, MD, Jorge Gonzalez-Canudas, MD, Paulina Trapaga, MD, Yulia Romero-Antonio, B.S. 2020-11-18
COVecu: Behavior and Experience of Communities Healthcare Professionals Facing the SARS CoV-2 (COVID-19) Epidemic Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-09-17 2021-01-31 AP-HP 200512, COVecu, NCT04625296 Phase Not Applicable Recruiting 1 4 Months 75 Flora DEVOS, Nurse MSC PhD, Flora DEVOS, nurse, Flora DEVOS, nurse Msc PhD, Marie BENHAMMANI 2020-11-13
The Potential of Oral Camostat in Early COVID-19 Disease in an Ambulatory Setting to Reduce Viral Load and Disease Burden Coronavirus disease 19 infection camostat mesylate alone, standard of care alone Serine protease inhibitor, Transmembrane serine protease 2 inhibitor, Trypsin inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitair Ziekenhuis Gent Belgium 2020-11-04 2023-01-01 2020-003475-18, NCT04625114 Phase 2 Clinical Recruiting 1 25 Months 150 Linos Vandekerckhove, Marie-Angélique De Scheerder 2020-11-17
SARCODO: Coagulopathy and Vasculopathy Assessment as a Predictor of the Severity of SARS-CoV-2/COVID-19 Infection Blood clotting disorder, Coronavirus disease 19 infection, Lung disease, Respiratory distress syndrome, Vascular disease Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris Agence nationale de la recherche (ANR) France 2020-06-08 2020-12-31 2020-A01048-31, APHP200521, NCT04624997, SARCODO Phase Not Applicable Recruiting 2 6 Months 1000 David M Smadja, David Smadja, Michaela FONTENAY, Natacha Nohilé 2020-11-18
NO-mediated Vascular Function in Covid-19 Patient Coronavirus disease 19 infection, Viral pneumonia ultrasound system (General Electric Medical Systems) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Istituti Clinici Scientifici Maugeri Spa Sb Universita di Verona Italy 2020-05-30 2020-12-31 ICS MAUGERI 2437 CE, NCT04625036 Phase Not Applicable Recruiting 1 7 Months 30 Mara Paneroni, PT, Paola Baiardi, Math 2020-11-18
A case-report study of a COVID-19 patient presented with psychotic disorder Coronavirus disease 19 infection, Delirium, Respiratory disorder, Viral pneumonia corticoid bolus alone, hydroxychloroquine alone, lopinavir alone, risperidone alone, ritonavir alone, tocilizumab alone 5-HT 2 receptor antagonist, Cytochrome P450 3A4 inhibitor, Dopamine D2 receptor antagonist, HIV protease inhibitor, HIV-1 protease inhibitor Male Universidad De Salamanca Phase Not Applicable Status not specified 0 1 2020-11-13
CHLORO-VID: Hydroxychloroquine for the Treatment of SARS-CoV2 (COVID 19): Pharmacokinetic Study Coronavirus disease 19 infection, Viral pneumonia hydroxychloroquine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire de Toulouse France 2021-01-31 2021-05-31 2020-A01094-35, CHLORO-VID, NCT04625218, RC31/20/0155 Phase Not Applicable Not yet recruiting 1 4 Months 40 Stéphanie RUIZ, PH, Stéphanie RUIZ, ph 2020-11-17
UNITY Global: International Registry of Healthcare Workers Exposed to COVID-19 Patients Coronavirus disease 19 infection SARS-CoV-2 antibody serology testing alone, pharmaco-epidemiological inferential analysis alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Certara Bill & Melinda Gates Foundation, COVID -19 Therapeutics Accelerator, PAREXEL International Kenya, Zambia, Senegal, Zimbabwe, Pakistan, South Africa, Uganda, Nigeria 2020-08-13 2021-10-31 CER-HCW-001, NCT04626076, UNITY Global Phase Not Applicable Recruiting 8 14 Months 10000 Craig Rayner, PharmD, Marta Martinez, PharmD, Roman Casciano, Masters, Zainab Samad, Dr. 2020-11-17
Burnout and resilience among internal medicine physicians in-training in a tertiary government hospital in Manila, Philippines during the COVID-19 pandemic: An exploratory mixed method study Acute stress disorder, Coronavirus disease 19 infection Philippine General Hospital Philippines 2020-04-15 2020-07-30 PHRR201103-003115 Phase Not Applicable Completed 3 3 Months Jhaki A. Mendoza, Maria Rosario M. Bayan, Marvin E. Marquez, Patricia Gregoria V. Mina-Cuano, Paula Isabel G Franco, Paula Isabel Gimena Franco 2020-11-18
Study of Recombinant Protein Vaccine with Adjuvant against COVID-19 in Adults 18 Years of Age and Older Coronavirus disease 19 infection SP-0253 alone COVID19 Spike glycoprotein modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) GlaxoSmithKline plc, Sanofi Pasteur Inc Kenya 2020-12-01 2022-04-30 PACTR202011523101903, VAT00002 Phase 2 Clinical Not yet recruiting 4 17 Months 34520 Fabienne Roche, Tirhani Maluleke, Videlis Nduba 2020-11-17
To study the effect of povidone iodine gargle and nasal drops on disease transmissibility in SARS-CoV-2 infected patients Coronavirus disease 19 infection povidone iodine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Uttar Pradesh University of Medical Sciences India 2020-11-12 CTRI/2020/11/029063 Phase 3 Clinical Not yet recruiting 1 32 Dr Amit Singh, Dr Naresh Pal Singh, Dr Pranav Sharma 2020-11-17
High chloride level, anemia and severity of COVID-19 Anemia, Coronavirus disease 19 infection, Hyperchloremia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kasturba Medical College and Hospital India 2020-12-21 CTRI/2020/11/029060 Phase Not Applicable Not yet recruiting 1 60 Vedaghosh Amara 2020-11-17
COVID Phase III: A Phase III, Randomized, Double-blind, Placebo-controlled, Multicenter Study to Evaluate the Efficacy, Safety, Immunogenicity,and Lot-to-Lot consistency of BBV-152, a Whole virion Inactivated Vaccine in Adults >/= 18 Years of Age Coronavirus disease 19 infection COVAXIN alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bharat Biotech International Ltd, Indian Council of Medical Research India 2020-11-11 BBIL/BBV152-C/2020 Version No: 3.0, COVID Phase III, CTRI/2020/11/028976 Phase 3 Clinical Not yet recruiting 23 25800 DR T S Selvavinayagam, Dr Akshata, Dr Anjan Jyoti Talukdar, Dr C Prabhakar Reddy, Dr Chadramani Singh, Dr E Venkat Rao, Dr Krishna Mohan, Dr Laxmi S Kumari, Dr Manish Multani, Dr Mohammad Shameem, Dr N T Awad, Dr Pajanivel Ranganadin, Dr Parul Bhatt, Dr Priti Meshram, Dr R Vasudev, Dr Raghavendra Gumashta, Dr Sagar Vivek Redkar, Dr Sanjay Kumar Rai, Dr Satyajit Mohapatra, Dr Savita Verma, Dr Shashikanth Muni, Dr Shiva Narang, Dr Simmi Dube, Dr Suman Kanungo 2020-11-18
Study to assess the impact of COVID 19 infection on pulmonary function tests in children Coronavirus disease 19 infection Spirometry alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Maulana Azad Medical College India 2020-11-20 CTRI/2020/11/029058 Phase Not Applicable Not yet recruiting 1 100 Dr Romit Saxena 2020-11-18
A study to assess the overall dietary practices among young and middle-aged adults pre and during COVID times Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Welcomgroup Graduate School of Hotel Administration India 2020-11-20 CTRI/2020/11/029041 Phase Not Applicable Not yet recruiting 1 317 Dr Meenakshi Garg, Kritthika Gonella, Sudeepti Pramod Nayak 2020-11-17
Can combination of Haldi, Pomegranate and Zinger extract tablets help in reducing duration of hospital stay of mild to moderate COVID-19 patients Coronavirus disease 19 infection Dantabija + Haridra + Zingiber officinale chewable tablet alone, Standard treatment alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Medical Sciences Patna India 2020-10-19 CTRI/2020/11/029038 Phase 3 Clinical Not yet recruiting 1 100 Dr Yogesh Kumar 2020-11-17
Multisystemic inflammatory syndrome in children (MIS-C) in COVID pandemic Coronavirus disease 19 infection, Inflammatory disease Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs) Institute of Child Health and Hospital for Children, Madras Medical College India 2020-11-29 CTRI/2020/11/029061 Phase Not Applicable Not yet recruiting 1 200 Dr V Poovazhagi, Prof Dr S Elilarasi 2020-11-17
ReCOVer: A study to identify the rehabilitation need in post-discharge COVID-19 survivors Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences India 2020-11-16 CTRI/2020/11/029036, ReCOVer Phase Not Applicable Not yet recruiting 1 384 Raktim Swarnakar, S L Yadav 2020-11-18
Biological E’s novel Covid-19 vaccine of SARS-CoV-2 for protection against Covid-19 disease Coronavirus disease 19 infection RBD-specific protein subunit vaccine (COVID-19), Biological E alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Biological E Ltd India 2020-11-16 BECT062/Covid-19-phase-I&II/CTP-01Ver: 1.1, CTRI/2020/11/029032 Phase 1/Phase 2 Clinical Recruiting 5 360 Dr A Venkateshwar Rao, Dr Chandramani Singh, Dr Puneet Misra, Dr Shiv Narang, Dr Venugopal, DrSubhash Thuluva, DrTSA Kishore 2020-11-20
Blood Glucose Management in Diabetic COVID-19 Patients Coronavirus disease 19 infection, Diabetes mellitus Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sardar Vallabh Bhai Patel Hospital India 2020-11-20 CTRI/2020/11/029059 Phase Not Applicable Not yet recruiting 1 100 Dr Janakkumar R Khambholja, Dr Suhag B Patel 2020-11-17
Measurement of nutritional and health status of Beedi workers before and during COVID times Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Welcomgroup Graduate School of Hotel Administration India 2020-11-20 CTRI/2020/11/029042 Phase Not Applicable Not yet recruiting 1 160 Dr Meenakshi Garg, Nithin, Shwetha Kotian 2020-11-18
Effect of corona virus disease on the mental state of anesthesiologists in India Coronavirus disease 19 infection, Psychiatric disorder Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Government Medical College and Hospital,Chandigarh India 2020-11-15 CTRI/2020/11/029040 Phase Not Applicable Not yet recruiting 1 383 Dr Sanjeev Palta, Kompal Jain 2020-11-15
The performance of a novel ultra-rapid diagnostic test in the detection of COVID 19, an observational and case controlled study Coronavirus disease 19 infection ASU CV19 device alone Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Canary Health Inc India 2020-11-18 CTRI/2020/11/029037 Phase Not Applicable Not yet recruiting 1 750 Prof Ashok Rattan 2020-11-16
Compare oxygen saturation from pulse oximetry and ABG in COVID-19 patients in ICU/HDU Coronavirus disease 19 infection pulse oximetry alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rajarajeswari Medical college and Hospital India 2020-11-15 CTRI/2020/11/029035 Phase Not Applicable Not yet recruiting 1 100 Nadia Rose, Ramya B Sriram 2020-11-16
Multicentric, observational study on Pediatric Multisystem Inflammatory Syndrome (PMIS) related to Covid-19 Coronavirus disease 19 infection, Inflammatory disease Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Sir Ganga Ram Hospital India 2020-11-19 CTRI/2020/11/029030 Phase Not Applicable Not yet recruiting 8 100 Dr Bharat Mehra, Dr Chandrashekhar, Dr Dhiren Gupta, Dr Mukul Pandey, Dr Nameet Jerath, Dr Rachna Sharma, Dr Swati Kalra, Dr Vinamra Manocha 2020-11-16
A pilot study to determine health concerns developed during COVID-19 pandemic in childhood cancer survivors and siblings of Tata Memorial Hospital, who are now grown up adults Cancer, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tata Memorial Hospital India 2020-11-12 CTRI/2020/11/029029 Phase Not Applicable Not yet recruiting 1 100 Dr Maya Prasad 2020-11-15
An open-label observational study on post covid complications and radiological pattern changes on those patients treated with ZingiVir-H Coronavirus disease 19 infection ZingiVir-H alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Pankajakasthuri herbal research foundation India 2020-11-15 CTRI/2020/11/029025 Phase 2 Clinical Recruiting 1 60 Dr J Hareendran Nair, Dr Shan Sasidharan, DrJHareendran Nair 2020-11-17
An online survey to compare the diet and physical activity management before and during COVID and how it is affected by education, occupation and income in people with diabetes belonging to middle and upper socioeconomic classes Coronavirus disease 19 infection, Non-insulin dependent diabetes Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Welcomgroup Graduate School of Hotel Administration India 2020-11-20 CTRI/2020/11/029009 Phase Not Applicable Not yet recruiting 1 200 DrMeenakshi Garg, Pooja M, Susan Maria 2020-11-16
A randomized, open-label, phase IV monocentric study evaluating the clinical effect of oral immunomodulatory therapy with IMUNOR in patients with moderate COVID-19 disease Coronavirus disease 19 infection Imunor alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Thomayerova Teaching Hospital Czech Republic 2020-002497-27, KFJ-2020-01_IMUNOR Phase 4 Clinical Recruiting 1 60 Skopek -trial coordinator 2020-11-17
Signs and symptoms and outcome of babies < 28 days age admitted during pandemic in a only COVID-19 hospital in North India Coronavirus disease 19 infection Newborn Infants (up to 5 months) Maulana Azad Medical College India 2020-11-17 CTRI/2020/11/029007 Phase Not Applicable Not yet recruiting 1 1000 Dr Ajay Kumar, Dr Ashish Jain 2020-11-16
Radiological And Laboratory Tests Corelation With Clincial Severity Of COVID19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) India 2020-11-16 CTRI/2020/11/029004 Phase Not Applicable Not yet recruiting 1 100 Dr Janakkumar R Khambholja, Dr Juhi Patel 2020-11-16
Long-term lung problem of children who were affected by corona virus Coronavirus disease 19 infection Spirometry alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) Christian Medical College, Vellore, India India 2020-11-16 CTRI/2020/11/029026 Phase Not Applicable Not yet recruiting 1 100 Dr P Madhan Kumar 2020-11-15
To assess the impact of COVID-19 on the Diet, lifestyle and physical activity of IT employees (20 to 30 years) Acute stress disorder, Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs) Welcomgroup Graduate School of Hotel Administration India 2020-11-20 CTRI/2020/11/029012 Phase Not Applicable Not yet recruiting 1 300 Dr Meenakshi Garg, Koilakonda Sreebhavya, Shivani Endabetla 2020-11-15
To study the overall impact of consumption of non-alcoholic beverages on working from home adults, pre and during COVID times Acute stress disorder, Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Welcomgroup Graduate School of Hotel Administration India 2020-11-20 CTRI/2020/11/029008 Phase Not Applicable Not yet recruiting 1 295 Dalia V R, Dr Meenakshi Garg, Shreya Majumdar 2020-11-12
KAP: Survey of Knowledge, Attitudes and Practices towards Covid-19 Pandemic Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry Tata Memorial Hospital India 2020-11-20 CTRI/2020/11/029006, KAP Phase Not Applicable Not yet recruiting 1 1000 Dr Pabashi Poddar 2020-11-12
Evaluation of the effect of interferon beta-1b in the treatment of COVID-19 Coronavirus disease 19 infection Variable regimens including hydroxychloroquine , interferon beta-1b, Iran Pharmaceutical Company , lopinavir + ritonavir HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dezful University of Medical Sciences Iran 2020-09-22 IR.DUMS.REC.1399.031, IRCT20200921048786N1 Phase 3 Clinical Recruiting 1 82 Leila Masoudi Yekta 2020-11-15
Message Fatigue_COVID-19 Coronavirus disease 19 infection, Psychiatric disorder Online Survey alone Healthy volunteers accepted Institute for Health Behavioural Research (IHBR) Malaysia 2020-11-12 2021-11-11 57105, NMRR-20-2434-57105 Phase Not Applicable Status not specified 1 12 Months Mr Albeny ak Joslyn Panting, Norbaidurah binti Ithnain 2020-11-12
Correlation of Chest CT findings to the Clinical Outcomes and Final Case Classification of COVID-19 patients admitted at a tertiary hospital in the Philippines Coronavirus disease 19 infection CT scan alone Philippine General Hospital 2020-06-28 2020-08-31 PHRR201023-003084 Phase Not Applicable Completed 0 2 Months Jeffrey P. Apo 2020-11-15
MMD-HP: Moral Distress among Healthcare Professionals in Malaysia during the COVID-19 Pandemic Coronavirus disease 19 infection, Psychiatric disorder Healthy volunteers accepted HOSPITAL SERI MANJUNG Malaysia 2020-12-01 2021-02-28 56862, MMD-HP, NMRR-20-2433-56862 Phase Not Applicable Not yet recruiting 9 3 Months 660 Chiew Shoen Chuen, Dr Sheila Gopal Krishnan 2020-11-17
COPOT: Ocular Trauma Trends During Covid-19 Pandemic Coronavirus disease 19 infection, Ocular disease Hospital Ampang Malaysia 2020-11-23 2020-12-14 57109, COPOT, NMRR-20-2422-57109 Phase Not Applicable Status not specified 1 Dr Timothy Liew Khai Wing 2020-11-18
A Study of Self-risk Behavioral Assessment of Covid-19 Disease Among Sabah State Residents Coronavirus disease 19 infection Self-risk Behavioral Assessment alone National Institutes of Health Malaysia Malaysia 2020-11-13 2020-12-01 57137, NMRR-20-2415-57137 Phase Not Applicable Status not specified 1 Mr Kamarul Zaman bin Salleh 2020-11-12
Prevalence of Right Ventricular Dysfunction and Its Association with COVID-19 Clinical Outcome: A Meta-Analysis Coronavirus disease 19 infection, Heart disease, Pulmonary artery hypertension Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitas Airlangga Indonesia 2020-11-11 UMIN000042424 Phase Not Applicable Not yet recruiting 1 1000 Eka Mulia 2020-11-15
Providing gold standard continuous medical education to combat COVID-19 Coronavirus disease 19 infection continuous medical education alone Healthy volunteers accepted Universiti Putra Malaysia Malaysia 2020-12-01 2021-05-31 57152, NMRR-20-2410-57152 Phase Not Applicable Not yet recruiting 1 6 Months Dr. Navin Kumar A/L Devaraj 2020-11-17
Prevention of Disease by SARS-CoV-2 (COVID-19) by Pre-Exposure Prophylaxis of Emtricitabine / Tenofovir disoproxil and Hydroxychloroquine in healthcare personnel: Randomized, Placebo-Controlled Clinical Trial Coronavirus disease 19 infection Variable regimens including Hydroxychloroquine , emtricitabine , tenofovir disoproxil fumarate DNA polymerase inhibitor, HIV-1 reverse transcriptase inhibitor, Nucleoside reverse transcriptase inhibitor Instituto Nac De Ciencias Medicas Y Nutricion Salvador Zubiran Mexico 3419 Phase 3 Clinical Status not specified 2 2020-11-15
Evaluating the effects of Adalimumab in patients with acute respiratory distress syndrome caused by COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome Variable regimens including Lopinavir/Ritonavir (Hetero Labs Limited) , adalimumab , interferon b1a TNF alpha ligand inhibitor, TNF binding agent Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Shahid Beheshti University of Medical Sciences, Laser Application in Medical Sciences Research Center Iran 2020-08-06 IR.SBMU.NRITLD.REC.1399.154, IRCT20151227025726N23 Phase 2/Phase 3 Clinical No longer recruiting 1 60 Atefeh Fakharian, Farzaneh Dastan, Zahra Mirshafiei Langari 2020-11-18
Covid-19 Infection and New Onset Type 1 Diabetes Coronavirus disease 19 infection, Insulin dependent diabetes Mixed-meal tolerance test alone, SARS-Cov-2 antibody test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital of South West Jutland Aarhus University Hospital, Steno Diabetes Center, Steno Diabetes Center Nordjylland, Steno Diabetes Center Odense Denmark 2020-11-01 2023-10-30 NCT04623697, S-20200119 Phase Not Applicable Recruiting 1 35 Months 600 Claus B Juhl, Claus B Juhl, MD PhD, Claus B Juhl, MD, PhD, Morten Bjerregaard-Andersen, MD PhD, Morten Bjerregaard-Andersen, MSc, PhD 2020-11-17
Melanoma Patients’ and Clinicians’ Satisfaction with Telehealth During COVID-19 Coronavirus disease 19 infection, Melanoma online survey alone, telehealth alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Melanoma Institute Australia Australia 2020-11-27 2021-01-01 ACTRN12620001167954p Phase Not Applicable Not yet recruiting 3 1 Month 100 Dr Iris Bartula 2020-11-17
The adequacy of user seal checking for N95 respirators compared to formal fit testing, a multicentered, observational study Coronavirus disease 19 infection 3M N95 Healthcare Particulate Respirator alone, Halyard Fluidshield N95 Particulate Filter Respirator alone, Surgical Mask 1860 Regular alone, Surgical Mask Regular alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Epworth HealthCare Australia 2020-05-29 2020-11-30 ACTRN12620001193965, U1111-1254-8633 Phase Not Applicable Recruiting 5 6 Months 187 Dr Helen Cass, Dr Jonathan Barrett 2020-11-12
Inroads: An open, naturalistic trial of the Inroads program, an internet-delivered early intervention to reduce anxiety and alcohol use among young people Alcoholism, Coronavirus disease 19 infection, Generalized anxiety disorder, Social phobia automated email and text reminders alone Adolescents (13-17 yrs), Young Adults (18-44 yrs) University of Sydney Australian Government Department of Health and Ageing Australia 2020-11-20 2022-06-20 ACTRN12620001195943, Inroads Phase Not Applicable Not yet recruiting 8 19 Months 541 Dr Lexine Stapinski 2020-11-17
A Pilot Study to Assess Safety and Efficacy of SIR1-365 in Patients With Severe COVID-19 Cardiovascular disease, Coronavirus disease 19 infection, Renal injury, Respiratory distress syndrome SIR1-365 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sironax USA 2020-12-15 2021-12-15 NCT04622332, SIR365-US-101 Phase 1 Clinical Not yet recruiting 0 12 Months 60 Simon Li, MD, PhD 2020-11-13
INSPIRE: Intravenous Infusion of CAP-1002 in Patients With COVID-19 Coronavirus disease 19 infection CAP-1002 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Capricor Inc, Capricor Therapeutics Inc US 2020-11-20 2021-06-30 CAP-1002-COVID-19-02, INSPIRE, NCT04623671 Phase 2 Clinical Recruiting 2 7 Months 60 David Brabham, MD, Megan Hazelrigg, Oren Friedman, MD, Tracey S Early, BS, MA, CCRP 2020-11-19
The relationship between COVID-19 Infection and new onset and prognosis of vasospastic angina: Multicenter, prospective study Angina, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Yokohama City University Yokohama City University Medical Center Japan 2020-07-10 UMIN000042248 Phase Not Applicable Recruiting 1 300 Jin Kirigaya, Yasushi Matsuzawa 2020-11-12
Efficacy of Vitamin D Treatment in Mortality Reduction Due to COVID-19 Coronavirus disease 19 infection, Viral pneumonia, Vitamin D deficiency Hidroferol alone Investigation Institute Bioaraba Fundacion Eduardo Anitua Spain 2020-11-09 2021-11-09 NCT04621058, VITD Phase 3 Clinical Recruiting 2 12 Months 108 Joaquin Durán, Joaquín Durán Cantolla 2020-11-15
TEMPO: Telemedical psychiatry and psychotherapy for children and adolescents during the Covid-19 pandemic: feasibility, acceptance, satisfaction and pandemic-specific mental stress Acute stress disorder, Coronavirus disease 19 infection Telemedicine psychotherapy alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) University of Cologne Charite Universitaetsmedizin Berlin, Charité Campus Virchow-Klinikum, University Hospital RWTH Aachen, University of Gottingen Germany 2020-12-01 20-1537, DRKS00023525, TEMPO, U1111-1260-8886 Phase 4 Clinical Not yet recruiting 1 300 Carolina Habbel, Manfred Döpfner, Stephan Bender 2020-11-12
CARDIO-COVID: Prognostic and Clinical Impact of Cardiovascular Involvement in Patients With COVID-19 Coronavirus disease 19 infection, Myocardial disease cardiopulmonary exercise test alone, cardiovascular magnetic resonance imaging alone, chest computerized tomography scan alone, electrocardiogram analysis alone, transthoracic echocardiogram analysis alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Istituto Clinico Humanitas Centro Cardiologico Monzino Spa - Irccs, IRCCS Policlinico San Donato, Istituti Clinici Scientifici Maugeri Spa Sb, Istituto Auxologico Italiano Italy 2020-10-01 2021-10-01 CARDIO-COVID, CARDIOCOVID, NCT04624503 Phase Not Applicable Recruiting 5 12 Months 500 Gianluigi Condorelli, Prof, Giulio Stefanini, Giulio Stefanini, Prof, Giulio Stefanini, Prof., Luigi Badano, Prof., Marco Guazzi, Prof, Piergiuseppe Agostoni, Prof., Sivlia Priori, Prof.ssa 2020-11-12
PIVOT With MI: Presumptively Initiating Vaccines and Optimizing Talk With Motivational Interviewing Coronavirus disease 19 infection motivational interviewing intervention (PIVOT with MI) alone Newborn Infants (up to 5 months) University of Colorado at Denver and Health Sciences Center Eunice Kennedy Shriver National Institute of Child Health & Human Development, National Institutes of Health, Portland State University, Seattle Children's Hospital, The Childrens Mercy Hospital, University of Missouri, University of Washington US 2019-09-01 2023-07-31 17-1274, 1R01HD093628-01A1, NCT03885232, PIVOT With MI Phase Not Applicable Recruiting 2 47 Months 1000 Douglas Opel, MD, MPH, Sean O'Leary, MD, MPH 2020-11-11
A clinical trial of MP-1032 (inhalation, COPD), MetrioPharm for the treatment of covid-19 Coronavirus disease 19 infection MP-1032 (inhalation, COPD), MetrioPharm alone Superoxide dismutase stimulator MetrioPharm AG Phase Not Applicable Planned 0 2020-11-11
CovIdentify: Using Smart Watches to Detect and Monitor COVID-19 Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Duke University US 2020-04-02 2022-02-01 CovIdentify, NCT04623047, PRO00106404 Phase Not Applicable Recruiting 1 22 Months 100000 Chris Woods, Jessilyn Dunn, Ryan Shaw 2020-11-13
Neurocognitive Functions of Recovered COVID-19 Patients Coronavirus disease 19 infection, Inflammatory disease, Psychiatric disorder Trier Social Stress Test alone, oral calculation test alone, speech test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) National Institute on Drug Dependence The Sixth Hospital of Peking University (Institute of Mental Health), Wuhan Wuchang Hospital China 2020-07-10 2020-12-10 NCT04622748, NIDD-2020-NEUROCOGNITION Phase Not Applicable Recruiting 1 5 Months 160 Guofu Huang, Dr, Lin Lu, Dr., Ping Wu, Dr. 2020-11-15
A Virtual Prospective Study Exploring Activity Trackers and COVID-19 Infections Coronavirus disease 19 infection Empatica E4 alone, Garmin vivosmart 4 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Evidation Health Inc Bill & Melinda Gates Foundation, Biomedical Advanced Research and Development Authority (BARDA), Eli Lilly & Co, US Department of Defense, Vir Biotechnology Inc US 2020-11-30 2021-05-31 COVID SIGNALS, NCT04623138 Phase Not Applicable Not yet recruiting 1 6 Months 950 Ernesto Ramirez, PhD, Joyce HN Nortey, MPH, MSBH, Luca Foschini, PhD 2020-11-13
Exercise Influence on COVID-19 Coronavirus disease 19 infection physical exercise alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidad De Salamanca Spain 2020-12-04 2021-04-04 08112020, NCT04624048 Phase Not Applicable Not yet recruiting 1 4 Months 30000 CARLOS MARTIN-SANCHEZ, DOCTOR 2020-11-14
Thromboprophylaxis for Patients in ICU With COVID-19 Coronavirus disease 19 infection, Thrombosis low molecular weight heparin alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto de Investigacion Sanitaria La Fe Clinica Universidad de Navarra, Hosp Univ & Politecn La Fe, Hospital Clinic of Barcelona, Hospital Universitario Doctor Peset, Hospital de Cruces, Hospital de Sant Joan Despi Moises Broggi, La Paz University Hospital (Madrid) Spain 2020-03-01 2020-11-30 NCT04623177, REGCOVID-19 Phase Not Applicable No longer recruiting 31 9 Months 950 Raquel Ferrandis, MD 2020-11-13
Clarithromycin Versus Azithromycin in Treatment of Mild COVID-19 Infection Coronavirus disease 19 infection clarithromycin alone, symptomatic treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) South Valley University Egypt 2020-04-01 2020-07-30 NCT04622891, SVU-MED-CHT019-420860 Phase 2 Clinical Completed 1 3 Months 300 Alaa Rashad, MD 2020-11-14
Clinical Role of Testosterone and Dihydrotestosterone and Which of Them Should be Inhibited in COVID-19 Patients - A Double-edged Sword? Coronavirus disease 19 infection, Respiratory failure 13-cis retinoic acid plus testosterone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Kafrelsheikh University Egypt 2020-11-30 2021-12-31 NCT04623385, SARS -2 Phase 4 Clinical Not yet recruiting 1 13 Months 1000 Mahmoud Elkazzaz, B.Sc in Biochemistry, Mahmoud Ramadan mohamed Elkazzaz 2020-11-14
RIVERSIDE: Evaluation of the use of video consultation in rheumatology in the context of the COVID-19 pandemic Coronavirus disease 19 infection video consultation alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Universitätklinikum Düsseldorf Germany 2020-11-15 DRKS00023430, IT-TEMP-36, RIVERSIDE Phase Not Applicable Not yet recruiting 1 300 Jutta Richter 2020-11-13
PROFACT-01: An Outpatient Study Investigating Non-prescription Treatments for COVID-19 Coronavirus disease 19 infection chlorine dioxide aqueous solution alone, zinc acetate alone, Variable regimens including Lactoferrin , chlorine dioxide aqueous solution , famotidine , green tea extract , zinc acetate Histamine H2 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Pakistan 2020-11-09 2021-01-31 NCT04621149, PROFACT-01, PROFACT-01 Phase 2 Clinical Not yet recruiting 1 2 Months 120 Jonathan Murphy, MD, MD(H), Mitchell B Liester, MD 2020-11-14
Longitudinal COVID-19 Antibody Testing in Indiana University Undergraduate Students Coronavirus disease 19 infection SARS-CoV-2 IgM/IgG serological test alone, SARS-CoV-2 rapid assay kit (colloidal gold) alone, personal protective behavior alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Indiana University US 2020-09-14 2020-12-31 2008293852, NCT04620798 Phase Not Applicable No longer recruiting 1 3 Months 1700 Molly Rosenberg, PhD 2020-11-15
Effectiveness and safety of plasma convalescent therapy in patients with COVID-19 Coronavirus disease 19 infection convalescent plasma alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ministry of Research and Technology Indonesia 2020-04-26 2020-12-13 003, ISRCTN16842454 Phase 2 Clinical Recruiting 1 7 Months 5 Dr Santosa 2020-11-14
CCP-Cancer UK: Companion study to educate and inform practice and guidelines regarding COVID-19 infection in cancer patients Cancer, Coronavirus disease 19 infection Aged Adults (65-79 yrs), Elderly Adults (80 and over) The Clatterbridge Cancer Centre NHS Foundation Trust Clatterbridge Cancer Research Trust, National Institute for Health Research (NIHR), United Kingdom Research & Innovation UK 2020-08-11 2022-08-24 CCP-Cancer UK, CPMS 46602, IRAS 285044, ISRCTN15019599 Phase Not Applicable Recruiting 2 24 Months 9000 Dr Coordinator 2020-11-18
Pilot, Feasibility Study of Remote Problem Management Plus for Adults Affected by COVID-19 (PM+) Coronavirus disease 19 infection, Psychiatric disorder Problem Management Plus low-intensity psychological intervention alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) New School University George Washington University US 2020-11-30 2021-09-30 2020-91-PM+, NCT04617262 Phase Not Applicable Not yet recruiting 1 10 Months 100 Adam Brown, PhD, Brandon Kohrt, MD, PhD, Kendall Pfeffer, MEd, MA 2020-11-14
TTTC: Taking Time to Connect: A Study of Programs for Hispanic Mothers Diagnosed With Cancer and Their Children Cancer, Coronavirus disease 19 infection Conexiones telephone sessions alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), European Ancestry New Mexico State University Fred Hutchinson Cancer Research Center, National Cancer Institute, University of Washington US 2019-04-16 2021-08-31 17894, NCT03951454, TTTC Phase Not Applicable Recruiting 3 28 Months 156 Frances M Lewis, PhD, Rebecca Palacios, PhD 2020-11-14
A Pilot Study on Efficacy and Safety of Ayurveda Combination in Patients With Mild-to-Moderate COVID-19 Coronavirus disease 19 infection Shanshamani Vati Plus alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Aarogyam UK All India Institute of Ayurveda, Government of India, Ministry of Ayush, Warwick University UK 2020-10-08 2020-11-03 AU/WU/ 06, NCT04621903 Phase Not Applicable Completed 1 26 Dipa Modi, Neha Sharma, Tanuja Nesari, Vishwesh Kulkarni 2020-11-20
plasmApuane CoV-2: Efficacy and Safety of Immune Covid-19 Plasma in Covid-19 Pneumonia in Non ITU Patients Coronavirus disease 19 infection, Viral pneumonia immune plasma infusion alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) L'Azienda USL Nord Ovest Italy 2020-05-15 2020-12-31 ATNONORDOVEST, NCT04622826, plasmApuane CoV-2 Phase 2 Clinical Recruiting 1 7 Months 50 Antonella Vincenti, Mirko lombardi, antonella vincenti, mirko lombardi 2020-11-14
Mental Health in Communities Affected by COVID-19 in Uganda Coronavirus disease 19 infection, Drug dependence, Generalized anxiety disorder, Major depressive disorder, Post traumatic stress disorder, Psychiatric disorder psycho-education intervention alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Makerere University Uganda 2020-11-01 2021-07-30 INTEGRATION OF MENTAL HEALTH, NCT04616989 Phase Not Applicable Not yet recruiting 1 8 Months 840 Dickens Akena, PhD 2020-11-13
Orthopedic Conservative Treatment in the Time of Covid-19 Pandemic Bone injury, Coronavirus disease 19 infection orthopedic conservative treatment alone Elderly Adults (80 and over) Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization Turkey 2020-03-11 2020-12-01 NCT04623346, TREATMENT IN THE TIME OF COVID Phase Not Applicable No longer recruiting 2 8 Months 262 Bulent KARSLIOGLU 2020-11-18
Efficacy and Safety of Acetyl L-Carnitine in COVID-19 Patients With Mild-to-Moderate Disease Coronavirus disease 19 infection, Viral pneumonia acetyl L-Carnitine alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone Palermo Italy 2020-12-15 2021-07-31 20201109, NCT04623619 Phase Not Applicable Not yet recruiting 1 7 Months 100 Antonio Cascio, MD, PhD 2020-11-19
A clinical trial of SARS-CoV-2-RBD nanoparticle vaccine, University of Washington for the potential prevention of COVID-19 infection Coronavirus disease 19 infection SARS-CoV-2-RBD nanoparticle vaccine, University of Washington alone Washington University School of Medicine, US Phase Not Applicable Planned 0 2020-11-11
COMPVID STUDY: Randomized, controlled study of inflammation inhibition in the treatment of pneumonia by the SARS-Cov-2 virus Coronavirus disease 19 infection, Viral pneumonia nomacopan alone Complement C5 factor inhibitor, Leukotriene BLT receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Eduardo de Menezes, Universidade Federal de Minas Gerais Brazil 2020-08-19 2021-01-31 35247020.9.0000.5124, 4.165.354, COMPVID STUDY, RBR-88bjcv, U111112603293 Phase 2 Clinical Recruiting 1 5 Months Glauciene Prado Alves Prado Alves, Mauro Martins Teixeira 2020-11-13
AEROBI - COVID: Effect of Moderate Physical Training on a bicycle associated with altitude simulation on the health status of people recovered from COVID-19 Coronavirus disease 19 infection hypoxia alone, normoxia alone, recovery alone, training alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Escola de Educação Física e Esporte de Ribeirão Preto, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, University of Sao Paulo Fundacao de Amparo a Pesquisa do Estado Sao Paulo Brazil 2020-09-11 2021-04-30 33783620.6.0000.5659, 33783620.6.3001.5403, AEROBI - COVID, RBR-5d7hkv, U1111-1260-7479 Phase Not Applicable Recruiting 1 7 Months 80 Atila Alexandre Trapé 2020-11-16
Hyperbaric Oxygen for COVID-19 Patients With Moderate to Severe Respiratory Distress Coronavirus disease 19 infection, Respiratory distress syndrome Standard of Care alone, hyperbaric oxygen alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) NYU Langone Health US 2020-11-16 2021-12-15 20-00897, NCT04619719 Phase 2 Clinical Not yet recruiting 2 13 Months 600 David Lee, MD, Sandra Wainwright, MD, Scott Gorenstein, MD 2020-11-12
CortiCORONA: Biomarkers for Dexamethasone Response in Sars-Cov-2/COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia dexamethasone alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Montpellier France 2020-11-05 2021-11-30 2020-A0206-33, CortiCORONA, NCT04619693, PHRCI-20-013, RECHMPL20_0292 Phase Not Applicable Not yet recruiting 2 12 Months 100 Alain Makinson, MD, Boris Jung, MD, PhD, Bourdin Arnaud, MD, PhD, Camille Roubille, MD, Clement Boissin, MD, Clément Boissin, MD, Clément Le Bihan, MD, David Morquin, MD, Edouard Tuaillon, MD, PhD, Jacques Reynes, MD, PhD, Jean-Pierre Mallet, MD, Jérémy Charriot, MD, Kada Klouche, MD, PhD, Khuder Alagha, MD, Nathalie Pansu, MD, Pierre Fesler, MD, Sébastien Bommart, MD, PhD, Vincent Le Moing, MD 2020-11-12
COVISTRESSNutr: Influence of the COVID-19 Pandemic on Stress and Eating Habits Acute stress disorder, Coronavirus disease 19 infection Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Clermont-Ferrand France 2020-04-01 2025-12-31 2020 COVISTRESS NUTRITION, COVISTRESSNutr, NCT04621084 Phase Not Applicable Recruiting 1 69 Months 1000 Frederic DUTHEIL, Lise Laclautre, lise laclautre 2020-11-16
Hydroxychloroquine, Azithromycin and Zinc for the Treatment of COVID-19 in the Outpatient Setting Coronavirus disease 19 infection Variable regimens including azithromycin , hydroxychloroquine , zinc sulfate Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) St. Francis Hospital, New York US 2020-11-30 2021-05-31 20-19, NCT04621461 Phase 4 Clinical Not yet recruiting 1 6 Months 750 Avni Thakore, MD, Elizabeth Haag, RN, Elizabeth S Haag, RN 2020-11-11
Effect of a Cloth Mask Physical Exercise session on Cardiovascular health, Feeling and Exercise Effort, Oxygen Quantity and Jumping Performance: Recommendation for Physical Mask Exercise during and after the COVID-19 global outbreak Cardiovascular disease, Coronavirus disease 19 infection cloth mask alone, exercise alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Universidade Federal do Rio Grande do Norte Brazil 2020-11-02 RBR-9b6kvp, U1111-1259-3641 Phase Not Applicable Not yet recruiting 1 30 Phelipe Wilde de Alcântara Varela 2020-11-11
Effectiveness of a mouthwash and toothpaste containing PHTALOX in controlling symptoms of COVID-19 and flu Coronavirus disease 19 infection, Influenza virus infection Kit for oral care alone, PHTALOX alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto Federal do Paraná - IFPR Brazil 2020-11-01 35530020.1.0000.8156, 4.355.065, RBR-8x8g36, U1111-1260-4839 Phase 3 Clinical Not yet recruiting 1 500 Marcelo Lupion Poleti 2020-11-12
COnV-ert: Plasma for Early Treatment in Non-hospitalized Mild or Moderate COVID-19 Patients Coronavirus disease 19 infection, Lower respiratory tract infection methylene blue treated convalescent anti-SARS-CoV-2 plasma alone, standard medical treatment alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundacio Lluita Contra La Sida Banc De Sang I Teixits, Germans Trias i Pujol Hospital, Grifols Biologicals Inc, irsiCaixa Foundation Spain 2020-10-30 2021-10-31 CONV-ERT, COnV-ert, NCT04621123 Phase 2 Clinical Recruiting 1 12 Months 474 ORIOL Mitjà Villar, MD,PhD, ORIOL Mitjà Villar, MD,Phd, Oriol Mitjà Villar, PhD, MD 2020-11-13
MOMA: Measurement of the effect of mouthwash against COVID-19 Coronavirus disease 19 infection Dentyl mouthwash alone, Ultradex alone, povidone-iodine alone Cardiff University Venture Life Ltd UK 2020-05-20 2020-12-27 IRAS 285247, ISRCTN25647404, MOMA Phase 2 Clinical Recruiting 3 7 Months 104 Prof Thomas 2020-11-17
Innovation of Audio-Visual Triage System in Combating the Spread of COVID-19 Infection and Its Efficacy: A Novel Strategy Anxiety disorder, Coronavirus disease 19 infection audio-visual triage system alone Healthy volunteers accepted, Young Adults (18-44 yrs) University of Lahore, Main Campus Pakistan 2020-03-21 2020-04-28 IRBEC/BIH/013-2020, NCT04621214 Phase Not Applicable Completed 1 1 Month 60 Dr Muhammad Mansoor Hafeez 2020-11-13
PROVID-19: Efficacy of Probiotics in Reducing Duration and Symptoms of COVID-19 Coronavirus disease 19 infection probiotic intake alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre hospitalier universitaire de Sherbrooke Lallemand Health Solutions Canada 2020-11-16 2021-03-31 2021-3700, NCT04621071, PROVID-19 Phase Not Applicable Not yet recruiting 1 4 Months 84 Audrey Hamel-Thibault, MSc, Blanche Senicourt, PhD, Jean-Charles Pasquier, Dr, Jean-Charles Pasquier, MD, PhD 2020-11-18
Investigating effect of Spirulina dietary supplementation on COVID-19 disease outcomes in patients admitted to Intensive Care Units Coronavirus disease 19 infection routine medication alone, spirulina supplement alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Islamic Azad University Iran 2020-11-21 IR.IAU.PS.REC.1399.063, IRCT20200720048139N1 Phase 2 Clinical Recruiting 1 138 Farshad Hashemian, Mahdi Shadnoush, Monireh Hatami 2020-11-23
ENDCOV-I: The Study Will Evaluate the Use of Nintedanib in Slowing Lung Fibrosis in Patients With Pulmonary Infiltrates Related to COVID-19 Coronavirus disease 19 infection, Interstitial lung disease, Pulmonary fibrosis nintedanib alone CSF-1 antagonist, FGF receptor antagonist, FGF1 receptor antagonist, FGF2 receptor antagonist, FGF3 receptor antagonist, Flt3 tyrosine kinase inhibitor, Lck tyrosine kinase inhibitor, Lyn tyrosine kinase inhibitor, PDGF receptor alpha antagonist, PDGF receptor antagonist, PDGF receptor beta antagonist, Src tyrosine kinase inhibitor, VEGF receptor antagonist, VEGF-1 receptor antagonist, VEGF-2 receptor antagonist, VEGF-3 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mount Sinai Medical Center Boehringer Ingelheim International GmbH US 2020-11-30 2021-07-31 ENDCOV-I, GCO 20-2147, NCT04619680 Phase 4 Clinical Recruiting 2 8 Months 120 Aditi Mathur, MD, Alona Lansky, Jigna Zatakia, Maria Padilla, MD 2020-11-13
Seroprevalence of COVID-19 antibodies Coronavirus disease 19 infection Adolescents (13-17 yrs), Young Adults (18-44 yrs) Kalinga Institute of Medical Sciences India 2020-11-15 CTRI/2020/11/028967 Phase Not Applicable Not yet recruiting 6 100 Ramnath Misra 2020-11-11
A study to observe the trend of SARS-CoV-2, Dengue and Chikungunya infection transmission in the general population Chikungunya virus infection, Coronavirus disease 19 infection, Dengue virus infection Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Biotechnology Industry Research Assistance Council India 2020-11-18 CTRI/2020/11/028968 Phase Not Applicable Not yet recruiting 1 5000 DrYuvarajJayaraman 2020-11-12
Effect of Group Otago Exercise Program on Cognitive Frailty in the Nursing Home: a Randomized Controlled Trial Cognitive disorder, Coronavirus disease 19 infection Otago exercise alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) The Second XiangYa Hospital of Central South University, Xiangya School of Medicine of Central South University Health and Family Planning Commission of Hunan Province China 2020-06-01 2020-10-13 ChiCTR2000039592 Phase 0 Clinical Completed 1 4 Months 62 Chen Xi 2020-11-12
Effect Of COVID-19 on breast cancer treatment and its outcome Breast tumor, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tata Memorial Hospital India 2020-11-16 CTRI/2020/11/028969 Phase Not Applicable Not yet recruiting 2 900 Dr Jince Mary Mathew, Dr Rajiv Sarin 2020-11-11
A clinical trial to assess JNJ-78436735 in youths aged 12 to 18 for COVID-19 Coronavirus disease 19 infection JNJ-78436735 alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Johnson & Johnson Phase Not Applicable Planned 0 2020-11-11
Intubation with VieScope versus Videolaryngoskopy in complete personal protecion gear in asimulated COVID-19-Patient - A randomized, controlled trial Coronavirus disease 19 infection Glidescope alone, VieScope alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Cologne Germany 2020-11-15 20-1465, DRKS00023406 Phase Not Applicable Not yet recruiting 1 35 Hannes Ecker 2020-11-12
COVID-19 Stress, Depression, and Anxiety Among Health Care Workers in Selangor Hospitals Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) HOSPITAL TENGKU AMPUAN RAHIMAH KLANG Malaysia 2020-11-09 2022-12-31 56884, NMRR-20-2388-56884 Phase Not Applicable Not yet recruiting 1 25 Months Dr Natasha Subhas 2020-11-15
Evaluation of the combined effect of Hesperidin,Artemisinin- Artemisia annua, Noscapine, N-acetylcysteine, Resveratrol supplements and high dose of vitamin C on treatment, clinical symptoms of non-hospitalization and hospitalization patients with symptomatic COVID-19 Coronavirus disease 19 infection Variable regimens including Artemisia annua - Artemisinin, Longlifenutri , N-acetyl cysteine, Osvah , hesperidin, Swanson , noscapine, Faran Shimi , resveratrol, A Squard , vitamin C, Daroupakhsh Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kerman University of Medical Sciences Iran 2020-10-07 IR.SIRUMS.REC.1399.033, IRCT20181030041504N1 Phase 3 Clinical No longer recruiting 1 100 Dr. Masoomeh Mohamadpour, Dr.Ali,Amjadi, دکتر علی امجدی 2020-11-13
The Prevalence of Malnutrition among Adult Patients with the Coronavirus Disease 2019 (COVID 19) in a Tertiary Government Hospital Coronavirus disease 19 infection, Malnutrition Philippine General Hospital Philippines 2020-07-14 2020-09-15 PHRR201109-003131 Phase Not Applicable Completed 1 2 Months Blessie Marie B. Perez, Harold Henrison Chiu, MD, Lia Aileen M. Palileo-Villanueva, MD, Ramon B. Larrazabal Jr. 2020-11-13
Knowledge and attitudes of healthcare personnel towards COVID-19 disease and infection control strategies in a tertiary-level government hospital and COVID-19 referral center in the Philippines Coronavirus disease 19 infection Healthy volunteers accepted Philippine General Hospital Philippines 2020-06-01 2020-12-01 PHRR201109-003132 PHRR201109-003132 Phase Not Applicable Recruiting 1 6 Months Janine G. Mendoza, Maria Sonia Salamat, MD, Nigel Cortez Santos 2020-11-11
Determination the therapeutic effect of Ivermectin and Sovodak on patients infected with COVID-19 Coronavirus disease 19 infection standard regimen therapy alone, Sovodak plus ivermectin Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Akam Tejarat Fartak Farasoo Iran 2020-10-16 IR.QUMS.REC.1399.228, IRCT20200408046987N2 Phase 2/Phase 3 Clinical Recruiting 1 150 Dr. Aliakbar Karami, Dr Elham Zsabganeh, Morteza Shakhs Niaee, Nematollah Gheibi 2020-11-12
Effect of Dexamethasone on treatment of COVID-19 Coronavirus disease 19 infection dexamethasone alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tehran University of Medical Sciences Iran 2020-09-11 IR.TUMS.MEDICINE.REC.1399.432, IRCT20201015049030N1 Phase 2 Clinical Recruiting 4 200 Ali Asadolahi Amin, Mahdi Mahmoudi, Maryam Akhtari, Mohamadreza Salehi, Mohammad Ali Sahraian, Mojtaba Hedayat Yaghoobi, Saeed Reza Jamali Moghadm 2020-11-11
Effect of recombinant erythropoietin in COVID-19 patients Coronavirus disease 19 infection, Viral pneumonia recombinant erythropoietin (r-EPO) alone, standard care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences India 2020-11-06 CTRI/2020/11/028959 Phase 2 Clinical Not yet recruiting 1 40 Ashutosh kumar singh, Prof Anjan Trikha 2020-11-11
Psychological burden in COVID-19 Anxiety disorder, Coronavirus disease 19 infection, Depression, Somatization disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) All India Institute of Medical Sciences India 2020-11-10 CTRI/2020/11/028954 Phase Not Applicable Not yet recruiting 1 100 Bichitra Nanda Patra 2020-11-10
FUSIC: Ultrasonography in COVID-19 patients with a focus on possible clinical diagnosis and management decisions Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Pushpagiri Institute of Medical Sciences & Research Centre India 2020-11-19 CTRI/2020/11/028938, FUSIC Phase Not Applicable Not yet recruiting 1 44 Manju Mathew 2020-11-10
Outpatient Treatment With CoVid-19 With Prexablu Coronavirus disease 19 infection NocUlite alone, low level light therapy alone, methylene blue (Prexablu) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto De Seguridad Y Servicios Sociales De Los Trabajadores Del Estado Mexico 2020-10-12 2020-12-30 064.I.2020, NCT04619290 Phase 1 Clinical Recruiting 1 2 Months 46 M. Eunice Rodríguez Arellano, Martha E. Rodríguez Arellano, MD, Paula Costa Urrutia, PhD, Robin Messier 2020-11-13
RE-CoV-ERY: Post-intensive Care Follow-up of Patients Hospitalized for an Acute Respiratory Distress Syndrome Caused by COVID-19 Coronavirus disease 19 infection, Post traumatic stress disorder, Respiratory distress syndrome Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire de Toulouse France 2020-07-27 2022-07-31 NCT04619368, RC31/20/0219, RE-CoV-ERY Phase Not Applicable Recruiting 1 24 Months 100 Fanny BOUNES, Fanny BOUNES, PH 2020-11-11
A trial to evaluate an at-home rapid antigen test for COVID-19 Coronavirus disease 19 infection at-home rapid antigen test alone Gauss Surgical Phase Not Applicable Status not specified 0 159 2020-11-10
Physical Activity a Vital Sign? 40 Steps to Safety Test for Patients With COVID-19 Coronavirus disease 19 infection 40-steps test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Betsi Cadwaladr University Health Board Oxford Brookes University UK 2020-11-03 2021-11-03 283998, NCT04618835 Phase Not Applicable Recruiting 1 12 Months 1000 Christian Subbe, Christian Subbe, DM, Dr Christian P Subbe, Laura Langshaw 2020-11-12
COVISTRESSWork: Influence of the COVId-19 Pandemic on Stress of Occupational Health Workers Acute stress disorder, Coronavirus disease 19 infection Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Clermont-Ferrand France 2020-06-01 2025-12-21 2020 COVISTRESS WORK, COVISTRESSWork, NCT04619576 Phase Not Applicable Recruiting 1 66 Months 1000 Frederic DUTHEIL, Lise Laclautre, lise laclautre 2020-11-11
Safety and Immunogenicity of COVI-VAC, a Live Attenuated Vaccine Against COVID-19 Coronavirus disease 19 infection COVI-VAC alone Healthy volunteers accepted, Young Adults (18-44 yrs) Codagenix Inc UK 2020-12-31 2022-05-31 CDX-COV-001, NCT04619628 Phase 1 Clinical Not yet recruiting 1 17 Months 48 Daryl Bendel, MD, Kingsley Eze, Sybil Tasker, MD, MPH 2020-11-17
Ultramicronized Palmitoylethanolamide (PEA) Treatment in Hospitalized Participants With COVID-19 Coronavirus disease 19 infection palmidrol + morphine (ultramicronized, severe chronic pain), FSD Pharma alone, standard of care alone Cannabinoid CB2 receptor modulator, Opioid receptor mu agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) FSD Pharma Inc 2020-11-15 2021-12-05 FSD201-03, NCT04619706 Phase 2a Clinical Not yet recruiting 0 12 Months 350 FSD BioSciences Head of Clinical Research 2020-11-10
Surfactant Protein D Levels in Covid-19 Infection: Case-Control Study Coronavirus disease 19 infection, Viral pneumonia Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kafkas University Turkey 2020-10-13 2020-11-02 CLINICAL-1, NCT04618861 Phase Not Applicable Completed 1 127 Ramazan Sbirli 2020-11-11
A Single-Dose Study to Determine the Safety and Tolerability of Intranasal REVTx-99 in Healthy Adult Volunteers Coronavirus disease 19 infection REVTx-99 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Linear Clinical Research Limited, Statistical Revelations Australia 2020-11-12 2020-12-24 2020-08-796, ACTRN12620001104943, ANZCTR380621, RVL-NHV01 Phase 1 Clinical Not yet recruiting 1 1 Month 32 Carol Odle, George Tidmarsh, Jasmine Williams 2020-11-10
ASK: Improving access to kidney transplantation Coronavirus disease 19 infection, Kidney transplantation Clinician letter alone, Home-based patient and family education and engagement alone, Remote virtual ‘visit’/link alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Bristol, Wellcome Trust Wellcome Trust UK 2018-01-01 2023-02-01 , SPONSOR'S NUMBER 2020-4883, WT 214554/Z/18/Z, ASK, IRAS 287507, ISRCTN10989132 Phase Not Applicable Not yet recruiting 3 61 Months 60 Dr Bailey 2020-11-19
COKITS: Screening for COVID-19 in Teachers, Childcare Educators, Pupils and Preschoolers Coronavirus disease 19 infection Anti-SARS-CoV-2 antibody testing alone, SARS-CoV-2 PCR test alone Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University Medicine Greifswald Government of Mecklenburg-Western Pomerania, Landesamt für Gesundheit und Soziales M-V Germany 2020-11-04 2021-03-31 BB 179/20, COKITS, NCT04619407 Phase Not Applicable Recruiting 1 4 Months 300 Karsten Becker, Prof. Dr., Lena Ulm, Dr., Nils-Olaf Hübner, Prof. Dr. 2020-11-11
A phase II clinical trial of 7HP-349 in combination with COVID-19 vaccine for the treatment of patients with COVID-19 infection Coronavirus disease 19 infection 7HP-349 plus COVID-19 vaccine CD11a agonist, CD49d agonist, ICAM-1 stimulator, Integrin agonist, Vascular cell adhesion protein 1 agonist 7 Hills Pharma Llc Phase 2 Clinical Planned 0 2020-11-13
A Comparison of Fiberoptic Endotracheal Intubation Between the Intubating Laryngeal Tube Suction and the LMA Protector Coronavirus disease 19 infection, Respiratory disease LMA Protector alone, disposable intubating laryngeal tube suction device alone, endotracheal tube (VBM Medizintechnik GmbH) alone, fiberscope (Karl Storz) alone, Variable regimens including fentanyl , nitrous oxide , oxygen , propofol, AstraZeneca/Fresenius , rocuronium bromide , sevoflurane Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) B'nai Zion Medical Center Israel 2020-11-01 2020-12-30 NCT04618926, PROTECTOR Phase Not Applicable Not yet recruiting 1 1 Month 80 LUIS.GAITINI, Luis Gaitini, M.D., Mostafa Somri, M.D. 2020-11-13
Effect of COVID-19 Pandemic on Vaccination Compliance Coronavirus disease 19 infection Infants (6-23 months), Preschool Children (2-5 yrs) Assiut University Egypt 2021-04-01 2022-05-01 EFFECT OF COVID ON VACCINATION, NCT04618796 Phase Not Applicable Not yet recruiting 1 13 Months 100 Gehad Gamal Ahmed, Gehad Gamal, resident doctor, Ismail lotfy, associated professor, Mohamed Hamdy, professor 2020-11-10
A Phase II Clinical Trial of Influenza virus Vector COVID-19 Vaccine for intranasal Spray (DelNS1-2019-nCoV-RBD-OPT1) Coronavirus disease 19 infection, Viral pneumonia COVID-19 XWG-03 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Beijing Wantai Biological Pharmacy Enterprise Co Ltd, Jiangsu Province Centers for Disease Control and Prevention China 2020-11-17 2021-12-17 ChiCTR2000039715 Phase 2 Clinical Not yet recruiting 1 13 Months 720 Fengcai Zhu, Xiangzhong Ye 2020-11-17
The impact of COVID-19 on selective orthopedic surgery in Shanghai Sixth People's Hospital Coronavirus disease 19 infection selective orthopedic surgery alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shanghai Sixth People’s Hospital China 2020-11-08 2020-12-08 ChiCTR2000039711 Phase Not Applicable Recruiting 1 1 Month 2000 Cunyi Fan, Tengfei Lou 2020-11-11
ProMusik: Prospective, cohort study on the incidence of SARS-CoV-2-infections (COVID-19) in professional orchestra musicians and choir singers Coronavirus disease 19 infection, Influenza virus infection, Upper respiratory tract infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Charite Universitaetsmedizin Berlin Germany 2020-10-02 DRKS00023385, EA1/237/20, ProMusik Phase Not Applicable Recruiting 10 2500 Anne Berghöfer 2020-11-11
Evaluation of the effectiveness of TAC cocktail in critically ill patients with COVID-19-induced pneumonia Coronavirus disease 19 infection, Viral pneumonia Variable regimens including ascorbic acid (Darou Pakhsh Co) , methylprednisolone (Pfizer) , thiamine (Darou Pakhsh Co) Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tehran University of Medical Sciences Iran 2020-04-04 IR.TUMS.VCR.REC.1399.070, IRCT20200415047080N2 Phase 2/Phase 3 Clinical No longer recruiting 1 30 Mohammad ali Sahraian, Rasol Aliannejad, Rasoul Aliannejad 2020-11-10
COVID-19 With Convalescent Plasma Coronavirus disease 19 infection convalescent plasma therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Southeast University China 2020-01-01 2020-11-01 COVID-19 CONVALESCENT PLASMA, NCT04616976 Phase Not Applicable Completed 1 10 Months 78 Chun Pan 2020-11-10
A clinical trial of NanoAgCide hand sanitizer on Coronavirus patients Coronavirus disease 19 infection colloidal silver (NanoAgCide) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) WeInnovate Biosolutions Pvt Ltd India 2020-10-31 CTRI/2020/10/028688 Phase 2 Clinical Recruiting 1 20 Dr Ramshyam C Agarwal, Prasad Bhagat, Subham Dutta 2020-11-10
SAFE KiDS Studie: Rapidly applicable surveillance process for COVID-19 in day care centers with dual swabs Coronavirus disease 19 infection RT-PCR alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Johann Wolfgang Goethe-Universitat Frankfurt am Main Hessian Ministry for Social Affairs and Integration, Roche Holding AG Germany 2020-06-18 2020-09-10 20-724, DRKS00023500, SAFE KiDS Studie Phase Not Applicable Completed 1 2 Months 1250 Sandra Ciesek 2020-11-11
Effect of dexamethasone or ibuprofen-acetaminophen combination for pain management in symptomatic apical periodontitis during COVID-19 outbreak: a retrospective cohort study Coronavirus disease 19 infection, Pain dexamethasone alone, acetaminophen plus ibuprofen Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Istanbul Medeniyet University 2020-10-04 TCTR20201027002 Phase Not Applicable Not yet recruiting 0 50 Hakan Arslan 2020-11-10
SILVAR: Siltuximab in Viral ARds (SILVAR) Study Coronavirus disease 19 infection, Respiratory distress syndrome siltuximab alone, standard-of-care alone Heat shock protein inhibitor, IL-6 receptor antagonist Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) EUSA Pharma Syneos Health Inc US 2020-11-02 2022-06-30 EUSA SYL 0004, NCT04616586, SILVAR Phase 3 Clinical Not yet recruiting 1 19 Months 555 Melahat Samali, Nancy E Zeleniak, Tina Karunaratne, Zainab Shahid, MD, Ph.D, Zainab Shahid, MD, PhD 2020-11-11
Study of the Commercial Scale SARS-CoV-2 Vaccine Against the Pilot Scale Among Adults, and Bridging Study of the Immunogenicity in Elderly Against That in Adults Coronavirus disease 19 infection CoronaVac alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sinovac Research & Development Co Ltd China 2020-10-31 2021-05-31 NCT04617483, PRO-NCOV-3001 Phase 3 Clinical Recruiting 1 7 Months 1040 Hengkui Zhi, Master, Hongxing Pan, Master 2020-11-09
KOVID: Impact of the COVID-19 Epidemic on the Hospital Journey of Patients With Cancer of the Digestive System Anal tumor, Biliary cancer, Colon tumor, Coronavirus disease 19 infection, Esophagus tumor, Gallbladder tumor, Gastrointestinal tumor, Liver tumor, Pancreas tumor, Rectal tumor, Small intestine cancer, Stomach tumor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Groupe Hospitalier Paris Saint-Joseph France 2020-12-01 2021-12-31 KOVID, KOVID, NCT04616950 Phase Not Applicable Not yet recruiting 1 13 Months 800 Anne BURONFOSSE, MD, Helene BEAUSSIER, PharmD, pHD 2020-11-11
A Clinical Study of Online Active Play Program With Adolescents Anxiety disorder, Coronavirus disease 19 infection, Depression Revival Active Program alone Children (6-12 yrs), Adolescents (13-17 yrs) Revival Active Aarogyam UK UK 2020-03-30 2020-07-28 NCT04618341, RAP/003 Phase Not Applicable Completed 1 3 Months 32 Nagamani Krishnamurthy, Rakesh Patel, Tejal Patel 2020-11-17
Home-based Exercise in COVID-19 Survivors Coronavirus disease 19 infection telemonitored home-based exercise training program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Sao Paulo Brazil 2020-09-26 2021-12-21 4.342.082, NCT04615052 Phase Not Applicable Recruiting 1 14 Months 60 Bruno Gualano, Bruno Gualano, PhD, Bruno Gualano, Phd 2020-11-09
Effect of Solution-Focused Support Program on Anxiety Levels of Parents During the COVID-19 Pandemic Anxiety disorder, Coronavirus disease 19 infection Solution-Focused Support Program alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Adiyaman University Research Hospital Turkey 2020-07-01 2020-12-30 2020/751, NCT04609722 Phase Not Applicable Recruiting 1 5 Months 60 Ceyda Başoğul, Ceyda Başoğul, PhD, Emriye Hilal Yayan, Mürşide .zengin, Mürşide Zengin 2020-11-09
Heart Up!: Reducing Hopelessness Through Improved Physical Activity in Adults With Heart Disease: With COVID-19 Considerations Coronavirus disease 19 infection, Ischemic heart disease, Myocardial infarction, Unstable angina Motivational social support from nurse alone, Motivational social support from nurse with additional support from significant other alone, mHealth intervention alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Illinois National Institute of Nursing Research US 2019-08-01 2023-05-31 2018-1485, 3R01NR017649-04S1, Heart Up!, NCT03907891, R01NR017649 Phase Not Applicable Recruiting 1 46 Months 225 Denise K Busman, MSN, Stacie Vanoosterhout, MS, Susan L Dunn, PhD 2020-11-11
Online MBI for Families Affected by PPDA Anxiety disorder, Coronavirus disease 19 infection, Depression mindfulness-based cognitive therapy alone, mindfulness-based stress reduction program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Children's & Women's Health Centre of British Columbia (C&W) Canada 2020-10-20 2022-08-31 H20-01884, NCT04617132 Phase Not Applicable No longer recruiting 1 22 Months 40 Katarina Tabi, S. Evelyn Stewart 2020-11-10
Nasal Photodisinfection COVID Proof of Concept Study Coronavirus disease 19 infection Steriwave nasal decolonization system (Ondine Biomedical, BC) alone, methylene blue alone, red-light exposure based photodisinfection alone Sunnybrook Health Sciences Centre Canada 2020-07-10 2021-05-31 NCT04615936, NasalPDF001 Phase 2 Clinical Recruiting 1 10 Months 100 Cari Whyne, PhD, Jeremie Larouche, MD, MSc, Ravi Tuazon, BSc 2020-11-09
Effect of Respiratory Versus Aerobic Training on Respiratory and Immunity Efficiency in Recovered COVID-19 Patients Coronavirus disease 19 infection diaphragmatic breathing training alone, endurance training alone, incentive spirometer alone, intermittent exercise alone, medical drug treatment alone, segmental breathing training alone, treadmill walking alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Cairo University Egypt 2020-07-02 2021-01-20 MAHA2020, NCT04613050 Phase Not Applicable Recruiting 1 6 Months 80 Heba Ahmed Ali Abdeen, Maii Fekry Foad, MD 2020-11-10
Management of appendicitis during the covid-19 pandemic (observational) Appendicitis, Coronavirus disease 19 infection Hyperspace Epic 2014 Version IU1, Epic Systems Corporation alone, Laparoscopic appendicectomy alone, Open appendicectomy alone Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cambridge University Hospitals NHS Foundation Trust Addenbrookes NHS Trust, Nuffield Health Bournemouth, University of Rochester Medical Center UK 2019-11-01 2020-10-06 NCT04615728, PRN8996 Phase Not Applicable Completed 1 11 Months 207 Mr Ramez Antakia, Mr 2020-11-10
Prevalence of Thrombosis in COVID-Patients Coronavirus disease 19 infection, Thrombosis Duplex ultrasound alone, blood test alone, cognitive test alone, smelling test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Klinikum Augsburg Germany 2020-11-04 2021-06-30 COVID THROMBOSE, NCT04615026 Phase Not Applicable Recruiting 1 7 Months 400 Alexander Hyhlik-Duerr, MD, Yvonne Gosslau, MD 2020-11-09
SUMMIT: Scaling Up Maternal Mental Health Care by Increasing Access to Treatment Anxiety disorder, Coronavirus disease 19 infection, Depression TelePsychiatry Program alone, manualized behavioral activation treatment alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mount Sinai Hospital Harvard Medical School, NorthShore University HealthSystem (NorthShore), Patient Centered Outcome Research Institute, St Michaels Hospital, Sunnybrook Health Sciences Centre, University of Colorado, Boulder, University of North Carolina, Women's College Hospital US, Canada 2020-01-06 2025-12-30 NCT04153864, PCS-2018C1-10621, SUMMIT Phase Not Applicable Recruiting 5 71 Months 1368 Anastasia Harris, Cindy-Lee Dennis, Daisy R Singla, PhD, Holly Krohn, Maria Michalowska, Richard K Silver, MD, Samantha Meltzer-Brody, MD, MPH, Simone Vigod 2020-11-09
An observational, retrospective, single-center study to determine the efficacy and safety of tocilizumab in patients with severe COVID-19 infection Coronavirus disease 19 infection tocilizumab alone Albert Einstein Healthcare Network Phase Not Applicable Status not specified 0 66 2020-11-06
ENSEMBLE 2: A Study of Ad26.COV2-S for the Prevention of SARS-CoV-2-mediated COVID-19 in Adults Coronavirus disease 19 infection JNJ-78436735 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Janssen Vaccines & Prevention BV Janssen Pharmaceuticals Inc South Africa, Colombia, US, Philippines, Spain, UK, France, Germany, Belgium 2020-11-06 2023-05-11 2020-003643-29, CPMS 46804, CR108916, ENSEMBLE 2, IRAS 288552, ISRCTN14722499, NCT04614948, VAC31518COV3009 Phase 3 Clinical Recruiting 0 30 Months 30000 Janssen Vaccines & Prevention B.V. Clinical Trial, Mr Malcolm Macartney, Ms Shola Ayeni, Study Contact 2020-11-23
FX-COVID: FX-06 to Rescue Acute Respiratory Distress Syndrome During Covid-19 Pneumonia Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia FX-06 alone Cadherin-5 modulator, Factor Ia modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-11-30 2021-07-31 2020-002056-20, APHP200495, FX-COVID, NCT04618042 Phase 2 Clinical Not yet recruiting 1 8 Months 50 BRECHOT Nicolas, MD, David HAJAGE, MD, Nicolas BRECHOT, MD 2020-11-09
An observational study to evaluate the correlation between complement activation and disease severity in patients hospitalized with COVID-19 Coronavirus disease 19 infection Apellis Pharmaceuticals Inc Phase Not Applicable Status not specified 0 41 2020-11-19
Analysis of the immunological response to coronavirus infection Coronavirus disease 19 infection Healthy volunteers accepted The University of Birmingham Department of Health and Social Care, Medical Research Council UK 2020-04-01 2025-06-05 CPMS 46588, IRAS 282164, RG_20-038 COVID-19, ISRCTN63911163 Phase Not Applicable Recruiting 4 62 Months 600 Dr Rachel Bruton, Prof Paul Moss 2020-11-09
SEMPATICO: Semaglutide to Reduce Myocardial Injury in Patients With COVID-19 Coronavirus disease 19 infection, Heart injury semaglutide (subcutaneous, diabetes/obesity/NASH), Novo Nordisk alone, standard of care alone Glucagon-like peptide 1 receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The University Health Network Canadian Institutes of Health Research, St Michaels Hospital, University of Toronto Canada, UK, Mexico, Brazil 2020-11-30 2022-03-31 NCT04615871, SEMPATICO, UHNSEMPATICO1 Phase 2 Clinical Not yet recruiting 10 16 Months 400 Andrei C Sposito, MD, Anil Gupta, MD, Beatriz Villegas, DDS, Carlos Fernando, Cheryl Geen-Smith, Daniela M Rosiles, MD, Eduardo Mateos, MD, Emily McDonald, MD, Gina Dutton, Jorge Escobedo, MD, Juan A Santillan, MD, Julieta Valenzuela, MD, Kim Connelly, MD, Mansoor Husain, MD, Priscilla Griffo, Rodrigo B Esper, MD, Sarah Elsayed, Ticiane Bovi, Vinoda Sharma, MD, Vladimir Dzavik, MD, Vladimír Džavík, MD 2020-11-09
IMMUNO-COVID19: Hyperimmune Plasma for Patients With COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome hyperimmune plasma alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ospedale Papa Giovanni XXIII Italy 2020-07-02 2022-07-02 IMMUNO-COVID19, IMMUNO-COVID19, NCT04614012 Phase Not Applicable Recruiting 1 24 Months 100 ANNA FALANGA, Anna Falanga 2020-11-09
Harnessing Network Science to Personalize Scalable Interventions for Adolescent Depression (TRACK to TREAT Phase II) Coronavirus disease 19 infection, Depression ecological sampling method app alone, psychoeducation alone, web-based behavioral activation single session intervention alone, web-based growth mindset single session intervention alone Children (6-12 yrs), Adolescents (13-17 yrs) State University of New York at Stony Brook US 2020-12-31 2024-08-31 IRB2019-00382, NCT04607902 Phase Not Applicable Not yet recruiting 1 44 Months 216 Jessica L Schleider, PhD 2020-11-09
PanDirect: Self-care Tools and Telephone Coaching for Depression and Anxiety During Pandemics Anxiety disorder, Coronavirus disease 19 infection, Depression lay telephone coaching alone, self-care tool alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) St. Mary's Research Center Canada 2020-10-21 2021-05-01 NCT04609371, PanDirect, SMHC-20-10 Phase Not Applicable Recruiting 2 6 Months 176 Mark Yaffe, Mark Yaffe, Professor, 2020-11-20
NEOTHROCOVID: Thromboembolic Risk Screening in Patients With Cancer and COVID-19 Cancer, Coronavirus disease 19 infection, Thromboembolism computed tomography scan alone, electrocardiography alone, iodine alone, peripheral venous ultrasound alone, transthoracic ultrasound alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Antoine Lacassagne (Nice) France, Monaco 2020-08-04 2021-09-15 2020/20, NCT04616846, NEOTHROCOVID Phase Not Applicable Recruiting 6 13 Months 120 Benjamin HOCH, MD-PHD, Christophe PERRIN, MD-PHD, Céline CELLIER-COËLLE, Denis DOYEN, MD-PHD, Jérome BARRIERE, MD-PHD, Jérôme DOYEN, MD-PHD, Ophélie CASSUTO, MD-PHD 2020-11-11
The Effects of Multi-modality Physiotherapy in Delaying or Preventing COVID-19 Patient From Admitting to ICU Coronavirus disease 19 infection, Viral pneumonia Threshold IMT device alone, conventional physical therapy alone, inspiratory muscle training alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Ministry of Health in Kuwait Kuwait 2020-11-01 2021-04-06 JALGHAITH, NCT04617119 Phase Not Applicable Not yet recruiting 1 5 Months 38 Abdulaziz Al-Husaini, MSc., DR. JASSIM ALGHAITH, Jassim M Alghaith, PhD. 2020-11-09
Food: A Three-Arm Study Examining Food Insecurity Interventions Breast tumor, Coronavirus disease 19 infection home grocery delivery alone, medically-tailored hospital-based food pantry access alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Memorial Sloan-Kettering Cancer Center Columbia University, Jacobi Medical Center, Lincoln Medical and Mental Health Center, Montefiore Health System, Queens Cancer Center of Queens Hospital, Roswell Park Comprehensive Cancer Center, St. Barnabas Medical Center, The Brooklyn Hospital Center US 2012-05-08 2022-05-31 12-099, Food, NCT01603316 Phase 2 Clinical Recruiting 7 120 Months 668 Caroline Hwang, MD, Francesca Gany, MD, MS, Francesca Gany, MD, PhD, Ilmana Fulger, MD, Jennifer Leng, MD, MPH, Tarek Elrafei, D.O. 2020-11-10
Compassionate Use of REGN-CoV2 for the Treatment of COVID-19 Coronavirus disease 19 infection REGN-CoV2 alone COVID19 Spike glycoprotein inhibitor Regeneron Pharmaceuticals Inc NCT04617535, R10933-10987-COV Phase Not Applicable Recruiting 0 2020-11-09
MIND-VR: Virtual Reality for COVID-19 Operators' Psychological Support Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection virtual reality-based protocol alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Fondazione IRCCS Istituto Neurologico Carlo Besta University of Milano-Bicocca Italy 2020-11-01 2021-11-01 MIND-VR, MIND-VR/BESTA, NCT04611399 Phase Not Applicable Not yet recruiting 1 12 Months 90 Eleonora F Orena, PhD, Federica Pallavicini, PhD 2020-11-10
Evaluation of antibody and cytokine detection in tears of COVID-19 patients Coronavirus disease 19 infection Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Postgraduate Institute of Medical Education and Research India 2020-11-10 CTRI/2020/11/028813 Phase Not Applicable Not yet recruiting 1 120 Reema Bansal 2020-11-10
AFFORD COVID: Asthma in Families Facing Out-of-pocket Requirements Due to COVID-19 Asthma, Coronavirus disease 19 infection AAFA's chat bot insurance navigation alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Harvard Pilgrim Health Care Asthma and Allergy Foundation of America, Harvard TH Chan School of Public Health, Patient Centered Outcome Research Institute, University of North Carolina US 2020-11-02 2023-01-31 AFFORD COVID, IHS-1602-34331, NCT04613739 Phase Not Applicable Not yet recruiting 1 26 Months 430 Alison Galbraith, MD, MPH, Lauren Cripps, MS 2020-11-10
Yoga program on COVID-19 patients Acute stress disorder, Coronavirus disease 19 infection integrated biofeedback based yoga program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Central Council for Research in Yoga and Naturopathy, Ministry of Ayush India 2020-11-04 CTRI/2020/11/028827 Phase Not Applicable Not yet recruiting 6 86 Dr Amit Agarwal, Dr Chhavi Gupta, Dr Deepak KK, Dr Minakshi Dhar, Dr Raghavendra Rao M, Dr Sudheer, Dr Sunitha Mondal 2020-11-09
CRI:SIS: COVID-19 Responsive Intervention: Systems Improvement Simulations (CRI:SIS) Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection Simulation intervention alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Yale University Agency for Healthcare Research and Quality US 2020-11-15 2022-11-15 1R01HS028340-01, 2000029372, CRI:SIS, NCT04614844 Phase Not Applicable Not yet recruiting 1 24 Months 84 Ambrose H Wong, MD, MSEd, Ambrose Wong, MD, MSEd, Leigh Evans, MD, Leigh V. Evans, MD 2020-11-10
Finding Wellness in the Pandemic Acute stress disorder, Alcoholism, Coronavirus disease 19 infection, Drug dependence trauma Informed Psychotherapy alone, trauma Informed Yoga alone Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) The University Of Lethbridge Canada 2020-11-01 2021-04-30 2020-096, NCT04615741 Phase Not Applicable Recruiting 1 6 Months 200 Cheryl Currie, Cheryl Currie, PhD 2020-11-11
SeroCovid < 19: A Prospective, COVID-19, Seroconversion Study in a Tertiary Pediatric Patient Cohort Coronavirus disease 19 infection SARS-CoV-2 serological assessment alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Universitair Ziekenhuis Gent Universitaet Gent Belgium 2020-10-29 2021-11-01 BC-08104, NCT04615000, SeroCovid < 19 Phase Not Applicable Recruiting 1 12 Months 1000 Filomeen Haerynck, MD, PhD, Levi Hoste, MD 2020-11-10
Understanding Reactions to Emotional Material in the Media During COVID-19 Coronavirus disease 19 infection, Psychiatric disorder Tetris game alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Uppsala University Sweden 2020-10-28 2021-01-15 2020-03991, NCT04608097 Phase Not Applicable Recruiting 1 2 Months 66 Emily Holmes, Prof, Laura Singh, PhD 2020-11-10
HLA-G-COVID: HLA-G Immuno-Inhibitor Checkpoint Study in Patients With COVID-19 Infection: Molecular and Cellular Assessment Coronavirus disease 19 infection cellular assessment alone, molecular assessment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopital Foch France 2020-10-19 2021-10-31 2020_0082, HLA-G-COVID, NCT04613297 Phase Not Applicable Recruiting 1 12 Months 120 Elisabeth Hulier-Ammar, PhD, Olivier BRUGIERE, PhD 2020-11-09
PACBACK: Spinal Manipulation and Patient Self-Management for Preventing Acute to Chronic Back Pain Coronavirus disease 19 infection, Lower back pain Spinal manipulation therapy alone, Supported-self management program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Minnesota Duke University, Oregon Health Sciences University, University of North Texas, University of Pittsburgh, University of Washington US 2018-10-25 COVID19_IMPACT, CSH-2018-26524, NCT03581123, PACBACK Phase 3 Clinical Suspended 3 1180 Gert Bronfort, PhD, DC 2020-11-09
Role of Physiotherapist in enhancing functional aerobic capacity in pulmonary rehabilitation in Covid-19 Patients Coronavirus disease 19 infection, Viral pneumonia pulmonary rehabilitation program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Apollo Hospitals Educational Research Foundation Indraprastha Apollo Hospital India 2020-11-07 CTRI/2020/11/028811 Phase Not Applicable Not yet recruiting 1 50 Seema Grover 2020-11-09
Side effects of drugs used in ICU Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Government Institute of Medical Sciences, Greater Noida India 2020-11-13 CTRI/2020/11/028800 Phase Not Applicable Not yet recruiting 1 100 Dr Nazia Nazir 2020-11-10
The study of psychological interventions either individually or in groups and comparing its effect in reduction of psychological distress in covid-19 positive patients Acute stress disorder, Coronavirus disease 19 infection individual psychotherapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) HBTMC and Dr RN Cooper Municipal General Hospital India 2020-11-02 CTRI/2020/11/028799 Phase Not Applicable Not yet recruiting 1 55 Dr Deoraj sinha, Dr Tejaswini Miskin 2020-11-09
TECC-Diabetes: Technology-enabled Collaborative Care for Diabetes Management During COVID-19 Acute stress disorder, Coronavirus disease 19 infection, Non-insulin dependent diabetes, Psychiatric disorder technology-enabled peer support-led collaborative care program alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre for Addiction and Mental Health Canada 2020-11-30 2021-03-31 104-2020, NCT04607915, TECC-Diabetes Phase Not Applicable Not yet recruiting 2 4 Months 30 Diana Sherifali, Farooq Naeem, Peter Selby, Rosa Dragonetti 2020-11-10
Effect of SARS-CoV-2 Equine Antiserum Immunoglobulin (Purified F[ab]2 fragment) in hospitalized COVID-19 patients with moderate disease Coronavirus disease 19 infection anti-SARS-CoV-2 hyperimmune equine immunoglobulin F(ab')2 fragment (iv, COVID-19), Biological E alone, standard of care alone Immunoglobulin agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Biological E Ltd India 2020-11-05 BECT063/Equine.CoV.Ab-Phase-I/CTP-01Ver: 1.1, CTRI/2020/11/028779 Phase 1 Clinical Not yet recruiting 2 72 Dr Chandramani Singh, Dr Kishore TSA, Dr Subhash Thuluva, Dr Venugopal 2020-11-23
COPREG: Prospective Evaluation of the Predictive Criteria of Severity for Respiratory Infection Due to COVID-19 Virus Coronavirus disease 19 infection, Respiratory tract infection Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire de Toulouse France 2020-04-27 2020-07-17 COPREG, NCT04615676, RC31/20/0141 Phase Not Applicable Completed 1 2 Months 4734 Charles-Henri HOUZE-CERFON 2020-11-10
Effect of COVID-19 on physical activity, screen time and emotional wellbeing on medical students Coronavirus disease 19 infection Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs) Sawai ManSingh Medical College India 2020-11-02 CTRI/2020/10/028744 Phase Not Applicable Not yet recruiting 1 200 Dr Anuradha Yadav 2020-11-10
HiFlo-COVID: High-Flow Nasal Cannula in Severe COVID-19 With Acute Hypoxemic Respiratory Failure Coronavirus disease 19 infection, Hypoxia, Respiratory failure High flow nnasal cannula oxygen therapy alone, High-flow nasal cannula alone, oxygen alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundacion Clinica Valle del Lili Colombia 2020-08-11 2021-07-28 001635, HiFlo-COVID, NCT04609462 Phase 2 Clinical Recruiting 1 11 Months 196 Gustavo A. Ospina Tascón, MDPhD, Sergio I. Prada, MPA PhD 2020-11-09
A phase III trial to evaluate the efficacy of recombinant new coronavirus vaccine (CHO cell) for the prevention of SARS-CoV-2 infection Coronavirus disease 19 infection SARS-CoV-2 protein subunit vaccine (COVID-19), Chongqing Zhifei Biological Products/ Institute of Microbiology, Chinese Academy of Sciences alone COVID19 Spike glycoprotein modulator Chongqing Zhifei Biological Products Co Ltd, Institute of Microbiology, CAS Phase 3 Clinical Planned 0 2020-11-06
Application of an intelligent mobile isolation operating cabin preventing COVID-19 infection Coronavirus disease 19 infection coronary angiography alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Beijing Tsinghua Chang Gung Hospital Tsinghua University China 2020-11-30 2021-11-29 ChiCTR2000039640 Phase 0 Clinical Recruiting 1 12 Months 10 Boda Zhou, Ping Zhang 2020-11-10
A Medical Records Based Study for noninvasive ventilation in patients with coronavirus disease 2019 (COVID-19) related acute hypoxemic respiratory failure Coronavirus disease 19 infection, Hypoxia, Respiratory failure Shenzhen People's Hospital China 2020-10-19 2020-11-13 ChiCTR2000039567 Phase Not Applicable Recruiting 1 40 Rongchang Chen, Yingyun Fu 2020-11-09
A study to evaluate the clinical effect of arbidol combined with adjuvant therapy in patients with COVID-19 Coronavirus disease 19 infection adjuvant therapy alone, arbidol alone Jiaxing University China Phase 2 Clinical Status not specified 1 62 2020-11-06
LKPCOVID19: Level of Knowledge and Preparedness for COVID-19 Pandemic Among Government Dental Officers in Perak, Malaysia: A Cross Sectional Study Coronavirus disease 19 infection Healthy volunteers accepted Taiping Hospital Malaysia 2020-11-18 2020-12-18 HSR2020-01 56920, LKPCOVID19, NMRR-20-2367-56920 Phase Not Applicable Not yet recruiting 1 1 Month 509 Dr FATIN ASHIKIN BINTI ABDUL MUTALIB 2020-11-10
DETECT: A clinical study to assess the use of wearable fitness devices for the early identification of COVID infection Coronavirus disease 19 infection Fitbit alone, wearable fitness device alone Scripps Research Institute US 2020-03-25 DETECT Phase Not Applicable Recruiting 1 100000 Jennifer Radin, PhD 2020-11-06
RaDiCo: PCR and Rapid Diagnostic Test on Saliva and Nasopharyngeal Swabs for the Detection of SARS-CoV-2 (COVID-19) Coronavirus disease 19 infection AAZ-LMB (COVID-VIRO) alone, Panbio COVID-19 Ag (Abbott) alone, Standard Q COVID-19 (Roche) alone, polymerase chain reaction alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Lausanne Centre Hospitalier Universitaire Vaudois Switzerland 2020-09-25 2020-12-31 2020-02269, NCT04613310, RaDiCo Phase Not Applicable Recruiting 1 3 Months 1250 Blaise Genton, MD PhD, Blaise Genton, MD, PhD, MPH, Blaise Genton, MD-PhD, Gilbert Greub, MD, PhD, Valerie D'Acremont, MD-PhD, Valérie D'Acremont, MD PhD 2020-11-14
An academic trial to study the prophylactic activity of Vishasura Kudineer (VSK) in healthcare workers exposed/non-exposed to COVID-19 patients Coronavirus disease 19 infection VSK decoction alone, Vishasura Kudineer (VSK), a Siddha formulation alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Ministry of Ayush India 2020-11-12 CTRI/2020/11/028905 Phase 1/Phase 2 Clinical Not yet recruiting 1 120 Dr K Prasanna Purna, Dr Sivakumar Vijayaraghavalu 2020-11-10
Telephonic intervention for people tested positive for Covid Coronavirus disease 19 infection tele counselling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Yenepoya medical college hospital India 2020-11-09 CTRI/2020/11/028903 Phase Not Applicable Not yet recruiting 1 Jeyaram 2020-11-10
COFIT-20: Exercise via videoconferencing for people with severe mental illness during covid-19 times, a feasibility study Coronavirus disease 19 infection, Psychiatric disorder Exercise alone, videoconferencing alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Universitair Medisch Centrum Utrecht The Netherlands Organisation for Health Research and Development Netherlands 2020-06-09 2021-01-31 20-313/C, COFIT-20, NL9007 Phase Not Applicable Recruiting 1 7 Months 70 Lisanne Koomen 2020-11-12
Seroprevalence Study Johor Coronavirus disease 19 infection Jabatan Kesihatan Negeri Johar Malaysia 2020-11-15 2021-01-15 57086, NMRR-20-2365-57086 Phase Not Applicable Status not specified 1 2 Months Dr Jeyanthini a/p Sathasivam 2020-11-11
Radiological Perspective of COVID-19 Coronavirus disease 19 infection, Viral pneumonia CXR alone, chest CT alone University of Malaya Malaysia 2020-11-04 2021-08-09 57031, NMRR-20-2362-57031 Phase Not Applicable Recruiting 1 9 Months 1000 Dr nadia fareeda binti muhammad gowdh, Prof Dr KARTINI BINTI RAHMAT 2020-11-11
PBPCDMSTKKDK: Covid-19 False News Spread on Social Media: a Review of the Community in Kelantan Coronavirus disease 19 infection Healthy volunteers accepted Jabatan Kesihatan Negeri Kelantan Malaysia 2020-11-15 2020-12-31 56117, NMRR-20-2355-56117, PBPCDMSTKKDK Phase Not Applicable Status not specified 1 1 Month Mr MOHD AZUAN BIN MUSTAPA 2020-11-12
KAPMASKCOVID-19: Assessment On The Use of Face Mask Among Health Care Workers In Health Clinic During COVID-19 Pandemic in Kelantan Coronavirus disease 19 infection Face Mask alone Healthy volunteers accepted Jabatan Kesihatan Negeri Kelantan Malaysia 2020-11-02 2020-12-31 56192, KAPMASKCOVID-19, NMRR-20-2346-56192 Phase Not Applicable Recruiting 1 1 Month Dr Izyan Auni Binti Mohamad, Dr NORAN BINTI HASHIM 2020-11-12
To Evaluate the Efficacy and Safety of ANT-V Syrup to Show Antiviral Action of Upper Respiratory Tract Like Common Cold and Act as an Immune Booster to Fight Against Infection, Flu, Fever, Sore Throat, Nasal and Chest Congestion Breathlessness in COVID-19 Patients Common cold, Coronavirus disease 19 infection, Upper respiratory tract infection ANT-V syrup alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Bhargava Phytolab Limited India 2020-11-16 CTRI/2020/11/028897 Phase 3 Clinical Not yet recruiting 1 60 Dr Rahul Singh, Pragya Singh 2020-11-11
COVID-19MASK: The Malaysian experience: Compulsory use of masks and preventive measures during COVID-19 Coronavirus disease 19 infection masks alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Selayang Hospital Malaysia 2020-10-30 2020-12-31 56946, COVID-19MASK, NMRR-20-2328-56946 Phase Not Applicable Recruiting 1 2 Months Dr NORLIZA MAT ARIFFIN 2020-11-12
Frailty Assessment for COVID-19 Severity Aging, Coronavirus disease 19 infection Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences India 2020-11-09 CTRI/2020/11/028885 Phase Not Applicable Not yet recruiting 1 100 Yudhyavir Singh 2020-11-06
Cancer Services during COVID-19 Pandemic – Importance of a Symptoms Based Screening Strategy Cancer, Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences India 2020-11-11 CTRI/2020/11/028859 Phase Not Applicable Not yet recruiting 1 400 Akash Kumar 2020-11-06
Lifestyle and psychological Changes During COVID 19 Lockdown Among Undergraduate Students in Chennai Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs) Sri Ramachandra Institute of Higher Education and Research India 2020-11-16 CTRI/2020/11/028848 Phase Not Applicable Not yet recruiting 1 526 Dr Akila GV 2020-11-06
A study on knowledge, attitude and behavior of healthcare workers on practices required to prevent COVID - 19 Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Shree Krishna Hospital, pramukhswami medical college India 2020-11-11 CTRI/2020/11/028846 Phase Not Applicable Not yet recruiting 1 200 Chirag Modi 2020-11-06
Outcomes of Nutrition scores on serious COVID patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Vardhman Mahavir Medical College & Safdarjung Hospital India 2020-11-09 CTRI/2020/11/028843 Phase Not Applicable Not yet recruiting 1 78 Saurav Mitra Mustafi, Saurav Mitra mustafi 2020-11-06
ERT-P: Emotion Regulation Training Via Telehealth During the COVID-19 Pandemic Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression emotion regulation training alone, internet-based online platform alone, videoconferencing software alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Teachers College, Columbia University University of Michigan US 2020-05-01 2023-01-31 20-269, ERT-P, NCT04615416 Phase Not Applicable Recruiting 1 33 Months 100 Douglas S Mennin, Ph.D., Douglas S Mennin, PhD 2020-11-06
Correlating the Clinical and CT Severity of COVID-19 Patients with the Inflammatory Markers and Co-morbidities Coronavirus disease 19 infection CB-NAAT alone, CT Thorax alone, GeneXpert alone, RT-PCR alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sri Ramachandra University Sri Ramachandra Institute of Higher Education and Research India 2020-11-15 CTRI/2020/11/028836 Phase Not Applicable Not yet recruiting 1 200 Aparna Ganesh, Preetam Arthur 2020-11-06
Clinical evaluation of STANDARD Q COVID-19 Ag Test Coronavirus disease 19 infection STANDARD Q COVID-19 Ag test alone Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) SD Biosensor Inc India 2020-10-30 CTRI/2020/10/028774 Phase Not Applicable Not yet recruiting 1 500 Dr Niraj Kothari 2020-11-09
HCBASE: Efficay of two hydroxychloroquine based drug combination regimens in comparison to standard of care in The Treatment of Hospitalized COVID-19 Patients Coronavirus disease 19 infection Variable regimens including azithromycin , hydroxychloroquine , lopinavir + ritonavir , zinc sulphate HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute for Pharmaceutical Research and Developments, Federal Republic of Nigeria University of Abuja Nigeria 2020-08-27 2021-03-01 HCBASE, PACTR202010519682638 Phase 2 Clinical Not yet recruiting 1 6 Months 210 Margaret Ekpenyong, Olobayo Kunle, Vivian Kwaghe 2020-11-11
Screening for COVID-19 Coronavirus disease 19 infection breath acoustic analysis alone, breathing sounds analysis algorithm alone, iPhone app (ID Fusion Software, Inc) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Manitoba Function Four Ltd, ID Fusion Software Inc, Natural Sciences and Engineering Research Council of Canada Canada 2020-11-15 2021-12-30 B2020:070 (HS24165), NCT04615208 Phase Not Applicable Not yet recruiting 1 13 Months 200 Mari Garcia, M.Sc., Zahra Moussavi, Ph.D. 2020-11-15
An observational study on the levels of IL-6 early after tocilizumab to distinguish survivors from non-survivors in COVID-19 pneumonia Coronavirus disease 19 infection, Pneumonia tocilizumab alone Azienda Ospedaliero-Universitaria di Udine Phase Not Applicable Status not specified 0 24 2020-11-05
FVR: Efficacy and Safety of Favipiravir in Covid-19 Patients in Indonesia Coronavirus disease 19 infection Standard of care alone, azithromycin plus favipiravir RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) INA-RESPOND Secretariat National Institute Of Health Research & Development (Nihrd)- Ministry Of Health Of The Republic Of Indonesia Indonesia 2020-10-15 2020-12-31 FVR, FVR, NCT04613271 Phase 3 Clinical Recruiting 3 2 Months 210 Dr Harli Amir Mahmudji, Dr Harli Amir Mahmudji, SpPD KEMD, Dr. dr. Armedy Ronny Hasugiana, M. Biomed, MD, dr. Adria Rusli, Sp.P, dr.Sofyan Budi Raharjo, SpP FISR 2020-11-06
Ketogenic Diet as Protective Factor During COVID-19 Coronavirus disease 19 infection ketogenic diet with phytoextract alone, low carbohydrate diet alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Padova San Bortolo Hosp Italy 2020-11-01 2021-08-30 KDSARS0120, NCT04615975 Phase Not Applicable Recruiting 1 9 Months 28 Antonio Paoli, MD, Lorenzo Cenci, MD 2020-11-09
E-COCCON: Effect of COVID-19-related Containment in Children Coronavirus disease 19 infection, Post traumatic stress disorder Children (6-12 yrs), Adolescents (13-17 yrs) Centre Hospitalier Universitaire de Toulouse France 2020-06-10 2020-11-30 E-COCCON, NCT04615195, RC31/20/0205 Phase Not Applicable Recruiting 1 5 Months 1000 AURIOL Françoise, PhD, CLAUDET Isabelle, Pr, Françoise Auriol, PhD, Isabelle CLAUDER, Pr, Isabelle CLAUDET, Pr 2020-11-06
IVIG in Patients With Severe COVID-19 Requiring Mechanical Ventilation Coronavirus disease 19 infection Octagam alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sharp HealthCare US 2020-11-01 2021-06-30 2010902, COVID-IVIG VENT, NCT04616001 Phase 4 Clinical Not yet recruiting 1 8 Months 10 George Sakoulas, MD, Kathryn Miller, Matthew Geriak, PharmD 2020-11-09
Squalene and COVID-19 Coronavirus disease 19 infection Variable regimens including chloroquine phosphate , hydroxychloroquine , lopinavir + ritonavir , microemulsion containing extracted squalene , ribavirin HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mashhad University of Medical Sciences Iran 2020-10-31 IR.MUMS.REC.1399.468, IRCT20200927048848N2 Phase 3 Clinical Recruiting 1 15 Deputy of Research and Technology, Mahmood Ebrahimi 2020-11-10
A proof of concept, investigator-initiated trial was to study efficacy of TD-213 in treating patients with confirmed mild to moderate COVD-19 infections Coronavirus disease 19 infection TD-213 alone TrippBio Inc US Phase Not Applicable No longer recruiting 1 Dr. Moti N. Ramgopal 2020-11-20
Recovery Profiles in Patients With SARS-CoV-2 Outcomes Undergoing Rehabilitation Coronavirus disease 19 infection, Psychiatric disorder comprehensive intensive rehabilitation alone, early rehabilitation alone, home mindfulness training alone, personalized ambulatory walking exercise alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Azienda Ospedaliero-Universitaria di Ferrara Italy 2020-03-30 2021-06-03 COVID19_REHABILITATION, NCT04615390 Phase Not Applicable Recruiting 1 14 Months 200 Alessandra Botti, MD, Anna Scotti, MD, Antonella Occhi, PT, Dino De Filippo, MD, Elisabetta Antiga, MD, Fabio Manfredini, MD, PhD, Francesca Filippini, PT, Francesco Baldasso, MD, Giada Milani, PsyD, PhD student, Giulia Bellon, MD, Giulia Dallagà, PsyD, Ilaria Ferioli, PT, Nicola Lamberti, PhD, Silvia Mottaran, PT, Sofia Straudi, Sofia Straudi, MD, PhD, Susanna Lavezzi, MD 2020-11-10
A phase III clinical trial of MP-0420 for the potential treatment of COVID-19 infection Coronavirus disease 19 infection MP-0420 alone Angiotensin converting enzyme 2 inhibitor, COVID19 Spike glycoprotein inhibitor Molecular Partners AG Novartis AG Phase 3 Clinical Planned 0 2020-11-05
A phase II clinical trial of MP-0420 for the potential treatment of COVID-19 infection Coronavirus disease 19 infection MP-0420 alone Angiotensin converting enzyme 2 inhibitor, COVID19 Spike glycoprotein inhibitor Molecular Partners AG Novartis AG Phase 2 Clinical Planned 0 2020-11-05
HFP: Home Fitness Project Coronavirus disease 19 infection exercise program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Kyoto University Japan 2020-10-30 HFP, UMIN000042340 Phase Not Applicable Recruiting 1 100 Norio Watanabe, Takashi Ishida 2020-11-06
Effect of Iranian Borage on the management of Covid-19 symptoms Coronavirus disease 19 infection Iranian borage aerial part alone, routine treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shiraz University of Medical Sciences Iran 2020-11-07 IR.SUMS.REC.1399.015, IRCT20201016049048N1 Phase 0 Clinical Recruiting 1 60 Ali Sahragard, Dr. Abbas Rezaeian zadeh, Mohammad Mehdi Zarshenas, Mohammad mehdi Zarshenas 2020-11-09
A phase II, randomized, open-label, two-arm study of silmitasertib versus standard of care or supportive care in the treatment of patients with moderately ill COVID-19 penumonia infection Coronavirus disease 19 infection, Viral pneumonia silmitasertib alone Casein kinase II inhibitor Senhwa Biosciences Inc US, Georgia Phase 2 Clinical Not yet recruiting 2 20 Dr Christopher P Recknor 2020-11-16
CardiolRx in Patients With COVID-19 and Cardiovascular Disease or Risk Factors Cardiovascular disease, Cerebrovascular disease, Coronavirus disease 19 infection, Diabetes mellitus, Hypertension, Obesity, Peripheral vascular disease cannabidiol (nanoformulation/subcutaneous, heart failure), Cardiol Therapeutics alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cardiol Therapeutics Inc US 2020-12-31 2021-09-30 CARDIOL 100-03, NCT04615949 Phase 2/Phase 3 Clinical Not yet recruiting 1 9 Months 422 Andrea B Parker, PhD, Dennis McNamara, MD, Dr. Arvind Bhimaraj, Dr. Barry Trachtenberg, Dr. Carsten Tschöpe, Dr. Leslie Cooper, Dr. Matthias Friedrich, Dr. Peter Liu, Dr. Wilson Tang, Eldon R Smith, MD 2020-11-06
VOC-COVID-Diag: Analysis of Volatile Organic Compounds in Exhaled Air and in Sweat in the Context of Suspicion of COVID-19 Infection Coronavirus disease 19 infection canine odor detection alone, electronic nose alone, mass spectrometry alone, volatile organic compound analysis alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopital Foch France 2020-10-21 2021-10-31 2020_0143, NCT04614883, VOC-COVID-Diag Phase Not Applicable Recruiting 1 12 Months 100 Elisabeth Hulier-Ammar, PhD, Helene Salvator, MD, Hélène Salvator, MD, Philippe Devillierr, MD PhD 2020-11-09
HOPE: The digital Hope program for people living with cancer during COVID-19 Cancer, Coronavirus disease 19 infection HOPE program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Coventry University UK 2020-03-31 2020-09-02 HOPE, IRRID: RR1-10.2196/24264, ISRCTN79623250 Phase Not Applicable Completed 2 5 Months 40 Dr Hayley Wright, Prof Turner 2020-11-06
An observational study to determine tocilizumab treatment for cytokine release syndrome in hospitalized patients with Coronavirus Disease 2019 Coronavirus disease 19 infection, Systemic inflammatory response syndrome tocilizumab alone Yale University Phase Not Applicable Status not specified 0 239 2020-11-06
Cov-Peru: Efficacy, Safety and Immunogenicity of Inactivated SARS-CoV-2 Vaccines (Vero Cell) in Healthy Adult Population In Peru Coronavirus disease 19 infection COVID-19 vaccine (inactivated, Vero cells/intramuscular), Beijing Biological Products Institute/National Institute for Viral Disease Control and Prevention of Chinese Center for Disease Control and Prevention alone, COVID-19 vaccine (inactivated, Vero cells/intramuscular), Wuhan Institute of Biological Products/Wuhan Institute of Virology, CAS alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidad Peruana Cayetano Heredia Universidad Nacional Mayor de San Marcos Peru 2020-09-10 2021-09-01 Cov-Peru, NCT04612972, UPERUANACH Phase 3 Clinical Recruiting 1 11 Months 6000 German Malaga, MD, Hugo García, PhD 2020-11-09
Lung Function, Exercise Capacity, and Serology Responses in Patients With COVID-19 Coronavirus disease 19 infection remdesivir alone, Variable regimens including interferon beta-1b , lopinavir + ritonavir , ribavirin COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, HIV protease inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chinese University of Hong Kong Health and Health Services Research Fund, The University of Hong Kong Hong Kong 2020-05-22 2022-05-21 2020.229, NCT04611243 Phase Not Applicable Recruiting 1 24 Months 80 David S Hui, MD, Karen Yiu, BSc, Susanna Ng, MBChB, Susanna So-Shan Ng 2020-11-06
COVID-19: Health-Related Quality of Life of Patients With Asthma During the Pandemic of COVID-19 Asthma, Coronavirus disease 19 infection, Lung disease Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cairo University Egypt 2020-05-01 2021-03-01 COVID-19, NCT04613245, SERIAL 39-2020 Phase Not Applicable Recruiting 1 10 Months 400 Naglaa Youssef, Youssef 2020-11-08
Clinical study on the efficacy and safety of Jieyuwan in the treatment of epidemic stress, anxiety and depression (stagnation of liver Qi syndrome) Anxiety disorder, Coronavirus disease 19 infection, Depression, Viral pneumonia Jieyuwan pill alone, psychological support therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Dongfang Hospital Tiansheng Pharmaceutical Group Co Ltd China 2020-11-15 2021-10-15 ChiCTR2000039536 Phase 4 Clinical Not yet recruiting 1 11 Months 390 Rongjuan Guo, Tian'ge Lu 2020-11-10
Evaluation of the Efficacy of Xylitol Nasal Spray Against SARS-CoV-2 Coronavirus disease 19 infection Xlear nasal spray alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Larkin Community Hospital Ferrer Medical Innovations Llc, Xlear Inc US 2020-08-08 2021-08-08 LCH-3-082020, NCT04610801 Phase 3 Clinical Recruiting 2 12 Months 200 CAMILLE GO, Camille Celeste Go, M.D., Camille Go, MD, Gustavo Ferrer, Gustavo Ferrer, M.D, Marcos Sanchez-Gonzalez, Marcos Sanchez-Gonzalez, MD 2020-11-18
PExCoV: Therapeutic Plasma Exchange as an Adjunctive Strategy to Treat Coagulopathy and Inflammation in Severe Covid-19 Blood clotting disorder, Coronavirus disease 19 infection, Inflammatory disease, Respiratory failure plasma exchange alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Zurich 2020-12-31 2021-12-31 NCT04613986, PExCoV, SD01 Phase Not Applicable Not yet recruiting 0 12 Months 20 2020-11-07
A phase IIa proof-of-concept study to evaluate safety and initial efficacy of AS-1411 for the treatment of COVID-19 Coronavirus disease 19 infection AS-1411 alone BCL2 gene inhibitor, Nucleolin inhibitor Qualigen Therapeutics Inc 2021-07-31 Phase 2a Clinical Planned 0 2020-11-20
COV2020: Medical-biological Research of the Pathogenesis of COVID-19 Disease Caused by SARS-CoV-2 Coronavirus disease 19 infection PCR testing alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Research Institute for Physico-Chemical Medicine of the Federal Medical-Biological Agency of the Russian Federation Burnasyan Federal Medical Biophysical Center, Federal Research Clinical Center of Federal Medical and Biological Agency, Federal State Budgetary Healthcare Institution, Hospital RAS, Federal'noe Gosudarstvennoe Bjudzhetnoe Uchrezhdenie "Nauchnyj Tsentr Problem Zdorov'ja Sem'i I Repr, Moscow city hospital named after S.I. Spasokukotskiy Russian Federation 2020-07-21 2022-12-31 COV2020, COV2020, NCT04611841 Phase Not Applicable Recruiting 1 29 Months 250 Vadim Govorun, MD 2020-11-14
SATICOVID19: Clinical Characteristics and Outcomes of Patients With COVID-19 on Mechanical Ventilation in Argentina Coronavirus disease 19 infection Mechanical ventilation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Argentina Intensive Care Society Argentina 2020-03-20 2020-10-31 NCT04611269, SATI, SATICOVID19 Phase Not Applicable Completed 5 7 Months 950 Elisa Estenssoro, MD 2020-11-17
Randomized, controlled trial to test the (cost)effectiveness of step-by-step, a smartphone-based self-help program for Syrian refugees in Egypt Acute stress disorder, Coronavirus disease 19 infection Step By Step app alone, information based treatment as usual alone, smartphone and internet-based self-help program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Berlin Free University EU Horizon 2020 Egypt 2020-12-01 2020-2021-009, DRKS00023505 Phase 2 Clinical Not yet recruiting 1 532 Sebastian Burchert 2020-11-08
A Study Looking at the Efficacy, Immune Response, and Safety of a COVID-19 Vaccine in Adults at Risk for SARS-CoV-2 Coronavirus disease 19 infection NVX-CoV2373 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Novavax Inc US Department of Health and Human Services, US Government Mexico, US, Puerto Rico 2020-11-30 2022-12-30 2019NCOV-301, NCT04611802 Phase 3 Clinical Not yet recruiting 110 25 Months 30000 Kristin Ciccarelli, Lisa M Dunkle, MD 2020-11-17
SeCoBelChild: Sero-prevalence COVID-19 Among Belgian Children Coronavirus disease 19 infection Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs) Sciensano Katholieke Universiteit Leuven, McGill University 2020-11-20 2021-08-31 NCT04613817, SC_044A, SeCoBelChild Phase Not Applicable Not yet recruiting 0 9 Months 1640 Els Duysburgh, MD, MPH, PhD, Melissa Vermeulen, MD 2020-11-05
A clinical trial of IMS-001 for the treatment of COVID-19 and  acute respiratory distress syndrome Coronavirus disease 19 infection, Respiratory distress syndrome IMS-001 alone AgeX Therapeutics Inc, Imstem Biotechnology Inc Phase Not Applicable Planned 0 2020-11-04
Open-label, Multicenter Study to Evaluate the Efficacy of PLX-PAD for the Treatment of COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome PLX stem cell therapy, Pluristem/Cha Bio & Diostech alone, best standard medical care alone IL-6 receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Pluristem Ltd, Pluristem Therapeutics Inc Israel, Germany 2020-11-30 2022-03-31 NCT04614025, PLX-COV-03 Phase 2a Clinical Recruiting 8 16 Months 40 Alona Paz, Dr, Alona Paz, Dr., Asaf Peretz, Dr, Asaf Peretz, Dr., Ayelet Raz-Pasteur, Dr, Ayelet Raz-Pasteur, Dr., Christian Karagiannidis, Prof. Dr, Christian Karagiannidis, Prof. Dr., Christian Putensen, Prof. Dr, Christian Putensen, Prof. Dr., Elias Mazen, Prof, Elias Mazen, Prof., Julia Kovalenko, Dr, Julia Kovalenko, Dr., Ronny Ben-Avi, Dr, Ronny Ben-Avi, Dr. 2020-11-05
REHSCU: Remimazolam Infusion in the Context of Hypnotic Shortage in the Critical Care Unit During the Pandemic of COVID-19 Coronavirus disease 19 infection remimazolam alone GABA A receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) CHU De Nantes PAION UK Ltd France 2020-11-01 2021-05-01 2020-003689-37, NCT04611425, RC20-0319, REHSCU Phase 2 Clinical Recruiting 1 6 Months 30 Antoine ROQUILLY, MD, PhD, Bertrand ROZEC, MD, PhD, Direction Recherche et Innovation, Raphaël CINOTTI, MD 2020-11-12
CoV-PREMOC: Sars-CoV-2 Infection (Covid-19) During Pregnancy: Effects on Mother and Child Coronavirus disease 19 infection biological sampling alone, magnetic resonance imaging alone, ultrasound alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Klinikum Grosshadern Der Ludwig-Maximilians-Universitat Germany 2020-11-06 20-733, CoV-PREMOC, DRKS00023447, LMU-RAD00530 Phase Not Applicable Not yet recruiting 1 30 Sophia Stöcklein, Vanessa Koliogiannis 2020-11-04
Effects of COVID-19 on levels of stress and anxiety in dental students Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Heidelberg Germany 2020-11-03 DRKS00023499, S-627/2020 Phase Not Applicable Recruiting 1 100 Andreas Zenthöfer, Anna-Luisa Klotz 2020-11-04
A prospective, multicentre, observational study to evaluate the feasibility of extracorporeal blood purification (EBP) using the company’s Oxiris filter set in severely ill patients with COVID-19 Coronavirus disease 19 infection Baxter's Prismaflex system alone, Oxiris filter set alone, extracorporeal blood purification alone Baxter International Inc Italy Phase Not Applicable Status not specified 1 37 Gianluca Villa 2020-11-04
Diagnostic Performance of an Antigen Test for SARS-CoV-2 Infection (COVID-19) Coronavirus disease 19 infection Quidel Sofia SARS Antigen Fluorescent Immunoassay alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Carilion Clinic US 2020-11-01 2021-01-31 EPLING-533, IRB-20-1088, NCT04610489 Phase Not Applicable Not yet recruiting 1 3 Months 800 John W Epling, MD 2020-11-05
CONTACT: A Study to Assess Infection Rate of Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2) and It's Affect on Quality of Life in Adult Volunteers in Lake County, Illinois Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) AbbVie Inc US 2020-10-30 2021-09-24 CONTACT, H20-308, NCT04611230 Phase Not Applicable Not yet recruiting 1 10 Months 1250 ABBVIE CALL CENTER, AbbVie Inc. 2020-11-05
SARS-COV2 Pandemic Serosurvey in a Rare Disease Population Coronavirus disease 19 infection, Rare disease Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Allergy and Infectious Diseases National Institutes of Health Clinical Center US 2020-11-25 2023-04-30 000210-I, 10000210, NCT04609085 Phase Not Applicable Recruiting 2 29 Months 5000 Matthew J Memoli, M.D. 2020-11-21
Aerosol Transmission of Severe Acute Respiratory Syndrome Coronavirus of Coronavirus Disease 2019 Coronavirus disease 19 infection Real-time-polymerase-chain reaction alone, cell culture alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Italiano de Buenos Aires Argentina 2020-05-08 2021-01-01 1345, NCT04609774 Phase Not Applicable No longer recruiting 1 7 Months 8 VANINA LAURA PAGOTTO 2020-11-05
Endothelial Damage and Angiogenesis Biomarkers During COVID-19 Coronavirus disease 19 infection, Vascular disease ELISA kit alone, enzyme-linked immunosorbent assay alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Chile Chile 2020-11-10 2021-11-30 NCT04609332, OAIC 1164/20, OAIC/20 Phase Not Applicable Recruiting 1 12 Months 40 Carlos Romero, M.D., Catalina Valdes, M.D., Felipe Andrés Maldonado Caniulao, Felipe Maldonado, M.D., M.Sc., Mónica Cáceres, Ph.D., Nicolas Valls, M.D., M.Sc., Oscar Cerda, Ph.D. 2020-11-19
A single-center, retrospective study to assess the effects of hydroxychloroquine on COVID-19 in intensive care unit patients Coronavirus disease 19 infection, Viral pneumonia hydroxychloroquine alone Aix-Marseille Université, Assistance Publique Hopitaux De Marseille Phase Not Applicable Status not specified 0 29 2020-11-06
Lung Diffusing Capacity for Nitric Oxide and Carbon Monoxide Early After Mild-to-severe COVID-19 Coronavirus disease 19 infection, Viral pneumonia European Ancestry IRCCS AOU San Martino – IST Italy 2020-05-14 2020-10-12 NCT04610554, SARS-COV-2_DLNO Phase Not Applicable Completed 1 4 Months 74 Giovanni Barisione, MD 2020-11-05
Mesenchymal Stem Cells in Patients Diagnosed With COVID-19 Coronavirus disease 19 infection, Lung injury, Multiple organ failure, Respiratory insufficiency adipose-derived mesenchymal stem cell therapy (iv, COVID-19), Instituto de Terapia Celular alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Instituto De Seguridad Y Servicios Sociales De Los Trabajadores Del Estado Instituto de Terapia Celular: ITC Mexico 2020-08-01 2020-12-30 060I.2020, NCT04611256 Phase 1 Clinical Recruiting 1 4 Months 20 M. Eunice Rodríguez Arellano, Martha E. Rodríguez Arellano, MD 2020-11-17
A clinical trial of NeuCovix-HT for the detection of functional antibodies in plasma or serum that neutralize the SARS-CoV-2 (COVID-19) virus Coronavirus disease 19 infection NeuCovix-HT alone Axim Biotechnologies Inc Phase Not Applicable Planned 0 2020-11-03
Long-term Follow-up in Survivors of Critical Illness Cognitive disorder, Coronavirus disease 19 infection, Psychiatric disorder, Respiratory distress syndrome, Viral pneumonia Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia Universita degli Studi di Brescia Italy 2020-06-01 2021-07-01 NCT04608994, NP2595 Phase Not Applicable Recruiting 1 13 Months 160 Nicola Latronico, Professor, Piva Simone, Simone Piva 2020-11-05
Delivery During COVID-19 Pandemic: Implications for Obstetrics, Maternal Psychopathology, and Mother-Infant Relationship Coronavirus disease 19 infection, Postnatal depression Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Hillel Yaffe Medical Center Israel 2020-06-01 2024-06-30 0082-20-HYMC, NCT04609501 Phase Not Applicable No longer recruiting 1 49 Months 440 Rinat Gabbay-Benziv, MD 2020-11-06
Surfactant Levels in the Lungs of COVID-19 Patients Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia lung fluid sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Zealand University Hospital Denmark 2020-11-01 2022-10-01 NCT04609488, SJ-859X Phase Not Applicable Not yet recruiting 1 23 Months 30 Henning B Nielsen, Henning Bay Nielsen 2020-11-05
Efficacy of Arbidol in treatment of COVID-19 Coronavirus disease 19 infection Variable regimens including Arbidol (Pharmstandard) , N-acetylcysteine , bromhexine , cetirizine , famotidine , fluticasone propionate , naproxen Histamine H1 receptor antagonist, Histamine H2 receptor antagonist Aged Adults (65-79 yrs), Elderly Adults (80 and over) Babol University of Medical Sciences Iran 2020-11-15 IR.MUBABOL.REC.1399.283, IRCT20201024049134N1 Phase 2 Clinical Recruiting 1 100 Mohammad Barary, Mostafa Javanian, Reza Ghadimi 2020-11-18
TeleRea'nCo: Follow-up of patients with COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopitaux Universitaires de Strasbourg France 2020-10-27 2023-04-27 7883, NCT04609839, TELEREA'NCO, TeleRea'nCo Phase Not Applicable Recruiting 1 30 Months 200 Eric DEMONSANT, Laurence KESSLER, Pr 2020-11-05
An observational, comparative study to evaluate the time to achieve negative nucleic acid testing and hospital stays between danoprevir and lopinavir/ritonavir in the treatment COVID-19 Coronavirus disease 19 infection danoprevir alone, lopinavir + ritonavir alone HIV protease inhibitor, Hepatitis C virus NS3 protease inhibitor Nanchang Ninth Hospital China Phase Not Applicable Status not specified 1 33 2020-11-04
Effectiveness of Tissue plasminogen activator (TPA) for treatment of ARDS induced by COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome regular care alone, alteplase plus enoxaparin sodium Low molecular weight heparin, Tissue plasminogen activator stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Tehran University of Medical Sciences Iran 2020-09-22 IR.TUMS.VCR.REC.1399.025, IRCT20200415047080N1 Phase 3 Clinical Recruiting 1 30 Mohhamad Ali Sahraian, Rasoul Aliannejad 2020-11-05
COVID-VIRO: Diagnostic Performance Evaluation of a Novel SARS-CoV-2 (COVID-19) Antigen Detection Test Coronavirus disease 19 infection COVID-VIRO novel antigen-based rapid detection test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Regional D'Orleans France 2020-10-13 2020-11-13 CHRO-2020-18, COVID-VIRO, NCT04609969 Phase Not Applicable Recruiting 1 1 Month 200 Aurélie DESPUJOLS, Elodie POUGOUE TOUKO, Thierry PRAZUCK, Thierry PRAZUCK, Dr, Thierry PRAZUCK, MD 2020-11-05
LidoCovid: Impact of Intravenous Lidocaine on Clinical Outcomes of Patients With ARDS During COVID-19 Pandemic Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia lidocaine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopitaux Universitaires de Strasbourg 2020-11-04 2024-02-04 7820, LidoCovid, NCT04609865 Phase 3 Clinical Not yet recruiting 0 39 Months 100 Thiên-Nga CHAMARAUX-TRAN, MD 2020-11-06
INSPIRE: Innovative Support for Patients With SARS-COV2 Infections (COVID-19) Registry Coronavirus disease 19 infection innovative support digital platform alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rush University Medical Center Jefferson Medical College, University of California Los Angeles, University of California San Francisco, University of Texas Health Science Center Houston, University of Texas Southwestern Medical Center, University of Washington, Yale University US 2020-11-14 2022-11-14 75D30120C08008, INSPIRE, NCT04610515 Phase Not Applicable Not yet recruiting 8 24 Months 4800 Ahamed Idris, MD, Anna Marie Chang, MD, Annie Lee, PhD, Bala Hota, MD, Doug Bell, MD, PhD, Elizabeth Vidales, Grace Amadio, Graham Nichol, MD, Henry Wang, MD, Jacqueline Brown, Joann Elmore, MD, Katherine Koo, Keith Jerome, MD, Kelli O'Loughlin, MD, Lauren Wisk, PhD, Matthew Thompson, MD, Michael Gottlieb, MD, Michelle Santangelo, Nicole Renzi, Nikki Gentile, MD, Paula Arellano-Cruz, Ralph Wang, MD, Raul Moreno, Robert A Weinstein, MD, Robert Rodriguez, MD, Robin Kemball, Victoria Lyon 2020-11-06
Evaluation of the efficacy and safety of Doxycycline in combination with standard treatment in Covid-19 patients Coronavirus disease 19 infection doxycycline alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shahid Sadoughi University of Medical Sciences and Health Services Iran 2020-09-14 IR.SSU.MEDICIN E.REC.1399.140, IRCT20191211045691N2 Phase 3 Clinical No longer recruiting 1 60 Dr.Masoud Mirzaei, Mohammad Bagher Owlia, Seyed Ruhollah Mousavinasab, Zohreh Akhoundi Meybodi 2020-11-05
Evaluation of the effect of ghamz with needle on improvement of respiratory symptoms of COVID-19 patients admitted to hospital Coronavirus disease 19 infection, Respiratory disease conventional medical treatment alone, ghamz massage-acupuncture therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Shiraz University of Medical Sciences Iran 2020-04-13 2020-07-20 IR.SUMS.REC.1399.043, IRCT20150825023753N17 Phase 3 Clinical Completed 1 3 Months 18 Dr. Amir Mohammad Jaladat, Dr. Mohammad Mahdi Parvizi, Dr. Younes Ghasemi 2020-11-05
Immune Defence: Evaluating nasal sprays and physical activity/stress management in reducing respiratory infections in primary care Coronavirus disease 19 infection, Respiratory tract infection Saline nasal spray alone, Vicks First Defence nasal spray alone, physical activity and stress management alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Of Southampton National Institute for Health Research (NIHR) UK 2019-09-01 2024-10-01 56474, IRAS 288431, CPMS 47080, ISRCTN17936080, Immune Defence Phase Not Applicable Recruiting 3 61 Months 15000 Dr Jane Vennik, Mrs Kate Martinson 2020-11-12
Evaluation of the Effectiveness of an Oral Antiseptic in Improving the Clinical Status, Decreasing Viral Load and Its Prolonged Action in Patients with COVID-19 Coronavirus disease 19 infection Tooth brushing alone, gargling / mouthwash a day alone, toothpaste alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Sao Paulo Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Brazil 2020-08-10 34070620.6.0000.5417, 4.212.624, RBR-58ftdj, U1111-1255-3454 Phase Not Applicable Recruiting 1 40 Bernardo da Fonseca Orcina, Paulo Sérgio da Silva Santos 2020-11-06
Aftogel and COVID-19 PCR test Coronavirus disease 19 infection Aftogel strip alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Exir Danesh Asia Co Iran 2020-11-21 IR.MUI.REC.1399.520, IRCT20181208041886N2 Phase 2 Clinical Recruiting 1 60 Dr. Mohsen Saniei, Dr. Morteza Pourahmad 2020-11-23
Study of ZnAg Liquid Solution to Treat COVID-19 Symptomatic Participants Coronavirus disease 19 infection CNM-AgZn-17 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Clene Nanomedicine Inc Azidus Brasil 2020-12-31 2021-08-31 CNMZNAG.202, NCT04610138 Phase 2 Clinical Not yet recruiting 0 8 Months 238 Renata Lourencini, Robert Glanzman, MD 2020-11-05
Redploy: Lessons from the frontline: the impact of redeployment during COVID-19 on nurse wellbeing, performance and retention Coronavirus disease 19 infection Bradford Teaching Hospitals NHS Foundation Trust National Institute for Health Research (NIHR) UK 2020-10-01 2022-03-31 ISRCTN18172749, NIHR132041, Redploy Phase Not Applicable Not yet recruiting 3 18 Months 48 Dr Jenni Murray, Prof Rebecca Lawton 2020-11-03
Effect of Melatonin in treatment of COVID-19 Coronavirus disease 19 infection melatonin alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hamadan University of Medical Sciences Iran 2020-10-22 IR.UMSHA.REC.1399.592, IRCT20200426047206N4 Phase 3 Clinical Recruiting 1 60 Dr Saman Talebi, Saeed Bashirian, Salman Khazaei 2020-11-03
Evaluation of the effect of mucodentol on people with coronavirus Coronavirus disease 19 infection mucodentol (Khorraman Pharmaceutical Company) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Lorestan University Iran 2020-04-25 IR.LUMS.REC.1399.046, IRCT20130428013151N2 Phase 0 Clinical No longer recruiting 1 200 Behrooz Farzan, Ebrahim Fallahi 2020-11-04
Study of the effects of grapefruit extract on COVID-19 Coronavirus disease 19 infection grapefruit seed extract (Nutribiotic Company) plus lopinavir + ritonavir HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Shaheed Beheshti Medical University Iran 2020-04-21 IR.SBMU.RETECH.REC.1399.041, IRCT20140312016968N2 Phase Not Applicable No longer recruiting 1 20 Dr. Afshin Zarghi, Dr. Aliakbar Velayati, Majid Marjani, Seyed Ali Ziai 2020-11-03
A clinical trial of COVID-19-specific T-cells for the treatment of COVID-19 Coronavirus disease 19 infection COVID-19-specific T-cells(Children's National Hospital) alone Children's National Hospital US Phase 1 Clinical Planned 1 2020-11-02
Infrastructure research for understanding the actual situation and pathophysiology of long-term complications of Coronavirus disease 2019 (COVID-19) Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) School of Medicine, Keio University Japanese Ministry of Health, Labor and Welfare Japan 2020-11-02 UMIN000042299 Phase Not Applicable Not yet recruiting 1 2000 Koichi Fukunaga, Makoto Ishii 2020-11-03
VoViThel: SARS-COVID-Endotheliitis Study via Retinal Vascular Analysis (COVID-19) Coronavirus disease 19 infection, Ocular disease flicker-light stimulation alone, intensive care therapy alone, retinal vascular analysis alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Jena University Hospital Germany 2020-09-14 2020-1805BO, DRKS00023334, VoViThel Phase Not Applicable Recruiting 1 30 Richard Biedermann 2020-11-04
Cod Liver Oil for COVID-19 Prevention Study Coronavirus disease 19 infection, Respiratory tract infection Cod liver oil alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Oslo University Hospital Norwegian Institute of Public Health, University of Oslo Norway 2020-11-10 2023-05-31 NCT04609423, REK-172796 Phase 4 Clinical Recruiting 1 30 Months 80000 Arne Søraas, MD, PhD, John Arne Dahl, PhD, Merete Ellingjord-Dale, PhD 2020-11-13
SECR-01: Efficacy and Safety of Two Hyperimmune Equine Anti Sars-CoV-2 Serum in COVID-19 Patients Coronavirus disease 19 infection Variable regimens including Equine Imunoglobulin anti SARS Cov 2 , acetaminophen , chlortrimeton , cimetidine Histamine H2 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Costa Rican social security box Ministry of Health of Costa Rica, Universidad De Costa Rica Costa Rica 2020-09-06 2020-12-06 NCT04610502, R020-SABI-00259, SECR-01 Phase 2 Clinical No longer recruiting 5 3 Months 26 Alfredo Sanabria, PhD, Willem Bujan, MBA 2020-11-18
Nano-COVID19: Treatment of Patients With Mild Coronavirus-19 (COVID-19) Disease With Methotrexate Associated to LDL Like Nanoparticles Coronavirus disease 19 infection didodecyl methotrexate (lipid nanoemulsion, myocardial infarction), University of Sao Paulo plus leucovorin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo Hospital Santa Marcelina Brazil 2020-10-27 2021-07-15 36746020.5.1001.0068, NCT04610567, Nano-COVID19 Phase 1/Phase 2 Clinical Recruiting 3 8 Months 100 Jose Salvador Oliveira, MD, PhD, Lucas Marinho, MD, Raul Cavalcante Maranhão, Raul Maranhão, MD, PhD, Rodrigo Esper, MD, PhD 2020-11-07
WIN COVID-19: Low dose lung X-ray therapy for COVID-19 Coronavirus disease 19 infection, Viral pneumonia Antibiotics alone, Low dose radiotherapy alone, statins alone, Variable regimens including Alteplase , Convalescent plasma , Dexamethasone , Enoxiparin , Methylprednisolone , Mycobacterium w , N acetyl cysteine , Oxygen , Paracetamol , Remdesvir , Tocilizumab , Ulinastatin , Vitamin C , Vitamin D , Zinc , pirfenidone , thiamine Interferon gamma receptor agonist, MAPK gene modulator, PDGF receptor antagonist, TGF beta receptor antagonist, TLR-2 agonist, TLR-4 agonist, TLR-9 agonist, p38 MAP kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) HarshaMitra Superspecialty Cancer Centre and Research Institute, Sundaram Hospital India 2020-11-06 CTRI/2020/10/028597, WIN COVID-19 Phase 2 Clinical Not yet recruiting 1 61 Govindaraj Ganesan, Sasipriya P, Vivek Sundaram 2020-11-04
Psychological coping with the COVID-19-pandemic Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder, Psychiatric disorder Google Forms program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Leukämie Lymphom Liga e.V.Universitätsklinikum Düsseldorf Germany 2020-05-12 2020-975, DRKS00021756 Phase Not Applicable Recruiting 1 9000 Jonas Jansen 2020-11-05
Trends of Symptoms in Patients Under Institutional Isolation in COVID-19 Pandemic in India - An Observational study Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Medical Sciences India 2020-10-26 CTRI/2020/10/028639 Phase 4 Clinical Not yet recruiting 1 1000 Dr Balbir Kumar 2020-11-03
To assess the overall effect of COVID-19 on intent of treatment and staging of cancer Cancer, Coronavirus disease 19 infection Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Max Super Speciality Hospital India 2020-11-02 CTRI/2020/10/028648 Phase Not Applicable Not yet recruiting 1 350 Dr Aditi Chaturvedi 2020-11-04
Clinical trial to study the effect of Budesonide taken through inhalation in mild COVID cases Coronavirus disease 19 infection Budesonide alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) sparsh chest diseases center Department of Health and Family Welfare, Government of Gujarat India 2020-10-23 CTRI/2020/10/028581 Phase 3 Clinical Not yet recruiting 4 1000 Dr Anand Patel, Dr Jayeshkumar Dobariya, Dr Jigna Dave, Dr Parul Vadgama, Dr Tushar Patel 2020-11-05
Effectiveness of an online training module with lectures and videos regarding maternal and newborn care during COVID 19 pandemic on the knowledge and acceptability among nursing students Coronavirus disease 19 infection E - learning module alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) AIIMS Rishikesh India 2020-10-26 CTRI/2020/10/028580 Phase Not Applicable Not yet recruiting 1 50 Levis Murry, cecilia mary 2020-11-04
Long-term Evolution of Pulmonary Involvement of Novel SARS-COV-2 Infection (COVID-19): Follow the COVID Study Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Policlinico S.Orsola-Malpighi Italy 2020-07-30 2021-07-30 714/2020/OSS/AOUBO, NCT04605757 Phase Not Applicable Recruiting 1 12 Months 100 Dr. Stefano Nava, Irene Prediletto, MD-PhD, Irene Prediletto, MD-Phd, Stefano Nava, MD, Stefano Nava, MD, FERS 2020-11-02
Evaluate the Safety, Immunogenicity and Potential Efficacy of an rVSV-SARS-CoV-2-S Vaccine Coronavirus disease 19 infection VSV vector-based vaccine targeting spike glycoprotein (COVID-19), IIBR/Weizmann Institute of Science alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Israel Institute for Biological Research Ministry of Health, Israel Israel 2020-10-28 2022-06-01 IIBR 20-001, NCT04608305 Phase 1/Phase 2 Clinical Recruiting 2 19 Months 1040 Eytan Ben Ami, Dr., Hadar Marcus, Dr., Noa Madar Balakirski, Dr., Yoseph Caraco, Prof. 2020-11-04
NICOVID: Evaluation of the Efficacy of Nicotine Patches in SARS-CoV2 (COVID-19) Infection in Hospitalized Patients Coronavirus disease 19 infection nicotine transdermal patch alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-11-30 2022-06-30 2020-003743-28, APHP200529, NCT04608201, NICOVID Phase 3 Clinical Not yet recruiting 1 19 Months 220 Valérie POURCHER, MD, PhD, Zahir AMOURA, MD, PhD, Zahir AMOURA, MD,PhD 2020-11-10
Treat COVID-19 Patients With Regadenoson Coronavirus disease 19 infection, Lower respiratory tract infection, Lung inflammation, Lung injury regadenoson alone Adenosine A2a receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Maryland Baltimore County US 2020-11-01 2022-01-31 HP-00091372, NCT04606069 Phase 1/Phase 2 Clinical Not yet recruiting 1 15 Months 40 Christine L Lau, MD, MBA, Manal Al-Suqi, MSTC, Melissa Culligan, RN 2020-11-05
ComCor: Study of Socio-demographic Factors, Behaviors and Practices Associated With Infection With SARS-CoV-2 Responsible for COVID-19 Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institut Pasteur Ipsos France 2020-10-27 2021-06-30 2020-047, 2020-A02560-39, ComCor, NCT04607941 Phase Not Applicable Recruiting 3 8 Months 57720 Arnaud Fontanet, Pr, Carole Blanc, Christophe David, Faiza Omar, Nathalie Jolly, Tiffany Charmet, DVM, MPH 2020-11-03
Inhaled NO for the Treatment of Viral Pneumonia in Adults Coronavirus disease 19 infection, Viral pneumonia LungFit alone, nitric oxide alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Beyond Air Inc 2020-11-07 2021-09-07 BA_VPLF_01, NCT04606407 Phase 2 Clinical Not yet recruiting 0 10 Months 90 Asher Tal, Meital Hatan, Rinat Kalaora 2020-11-04
PURIFY-OBS-1: PURIFY-OBS: Blood Purification With Seraph 100 Microbind Affinity Blood Filter for Treatment of Severe COVID19 Observational Study Acute lung injury, Adult respiratory distress syndrome, Coronavirus disease 19 infection, Respiratory failure Seraph 100 Microbind alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Henry M Jackson Foundation for the Advancement of Military Medicine Uniformed Services University of the Health Sciences US 2020-11-20 2022-02-01 NCT04606498, PURIFY-OBS-1, PURIFY-OBS-1 Phase Not Applicable Not yet recruiting 1 14 Months 200 Ian Stewart, MD, Katie Lyon, MS, Kevin Chung, MD, Marianne Spevak, BSHS, Stephen Olsen, MD 2020-11-19
AirS: SARS-CoV-2 in Air (COVID-19) Coronavirus disease 19 infection air sampler alone, breath sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Bonn Germany 2020-11-16 398/20, AirS, DRKS00023435 Phase Not Applicable Not yet recruiting 1 15 Ricarda Schmithausen 2020-11-03
ELISA: Lubecker longitudinal study on Infections with SARS-CoV-2 (COVID-19) Coronavirus disease 19 infection SARS CoV-2 sequencing alone, brief smell identification test alone, enzyme-linked immunosorbent assay alone, metabolite test alone, peripheral blood mononuclear cell analysis alone, polymerase chain reaction test alone, serum antibody test alone, urine analysis alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitatsklinikum Schleswig-Holstein Campus Lubeck, University of Lubeck Deutsche Forschungsgemeinschaft (DFG), German Federal Ministry of Education and Research Germany 2020-05-06 20-150, DRKS00023418, ELISA Phase Not Applicable Recruiting 1 3000 Alexander Katalinic, Christine Klein 2020-11-03
A study to assess safety and efficacy of emricasan for the potential treatment of mild-COVID-19 Coronavirus disease 19 infection emricasan (iv, liver transplantation/portal hypertension), Conatus alone Caspase inhibitor Amerimmune Llc US Phase 1 Clinical Not yet recruiting 1 2020-11-17
LAPCOV: Laparoscopy and COVID-19 Contamination Coronavirus disease 19 infection laparoscopy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-11-01 2022-01-01 APHP200611, LAPCOV, NCT04608383 Phase Not Applicable Not yet recruiting 1 14 Months 20 Laura RUSCIO, Laura RUSCIO, MD, PhD 2020-11-04
MBI: Evaluation of Occupational Burnout and Stress Among Dentists in Covid-19 Pandemic Acute stress disorder, Coronavirus disease 19 infection Akdeniz University Turkey 2020-03-09 2020-05-20 KAEK- 590, MBI, NCT04605692 Phase Not Applicable Completed 1 2 Months 706 Merve Özarslan 2020-11-03
CoRe (ADHOK): SARS-CoV-2 (COVID-19) registry for oncological and hematological patients in Germany Aplastic anemia, Cancer, Coronavirus disease 19 infection, Immune thrombocytopenic purpura, Myelodysplastic syndrome, Myeloproliferative disorder, Paroxysmal nocturnal hemoglobinuria Arbeitsgemeinschaft der Hamatologen und Onkologen im Krankenhaus e.V., St. Marien-Krankenhaus Siegen gem. GmbH Klinikum Bayreuth Klinik und Institut für Nuklearmedizin Germany 2020-06-01 CoRe (ADHOK), DRKS00023012 Phase Not Applicable Recruiting 26 170 Alexander Kiani, Romina Rösch 2020-11-10
Orthopedic Surgery in The Pandemic Era Coronavirus disease 19 infection SARS CoV-2 immunoglobulin G and IgM antibody test alone University of Indonesia Indonesia 2020-04-01 UMIN000042052 Phase Not Applicable Completed 1 35 Achmad Kamal, I Wayan Arya Mahendra Karda 2020-11-02
FIBRO-COVID: Pirfenidone compared to placebo in post-Covid19 pulmonary fibrosis Coronavirus disease 19 infection, Pulmonary fibrosis, Respiratory distress syndrome, Viral pneumonia Corticosteroid treatment alone, pirfenidone alone PDGF receptor antagonist, TGF beta receptor antagonist, p38 MAP kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institut Investigació Biomèdica Bellvitge Spain 2020-08-01 2021-08-01 2020-002518-42, FIBRO-COVID, NCT04607928 Phase 2 Clinical Recruiting 8 12 Months 148 Claudia Valenzuela, PI, David Jimenez, MD, PhD, Diego Castillo, PI, Eva Balcells, PI, Guadalupe Bermudo, MD, PhD, Guadalupe Bermudo, PI, Jacobo Sellarés, PI, Juan Rigual, PI, Karina Portillo, PI, Maria Molina, Maria Molina-Molina, MD, PhD, Piedad Usetti, MD, PhD, Rosalia Laporta, PI 2020-11-04
A retrospective, case series to evaluate the outcomes and biomarkers analyses among patients with COVID-19 treated with sarilumab in Italy Coronavirus disease 19 infection sarilumab alone IL-6 receptor antagonist Fondazione G Pascale Italy Phase Not Applicable Status not specified 1 15 2020-10-30
CVP-Covid19: Cardiovascular Disease Progression and Prognosis in COVID-19 Cardiovascular disease, Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universita di Bologna Italy 2020-09-20 2021-12-31 CVP-Covid19, CV_SPP_COVID19, NCT04606732 Phase Not Applicable Recruiting 1 15 Months 2000 Maria Carla Re, Olivia Manfrini, Olivia Manfrini, MD 2020-11-04
PICN: Psychological Impact of Covid-19 Among Nurses in Hospital Sultanah Nora Ismail, Batu Pahat Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression HOSPITAL SULTANAH NORA ISMAIL, BATU PAHAT Malaysia 2020-11-01 2021-03-31 NMRR-20-2291-55972, PICN, PICN 1.0, Version 1. 55972 Phase Not Applicable Not yet recruiting 1 5 Months 787 NURUL ASYHIKIN BINTI MOHD FADZIL 2020-11-08
ARBs CORONA II: Host Response Mediators in Coronavirus (COVID-19) Infection: Is There a Protective Effect of Losartan on Outcomes of Coronavirus Infection? Coronavirus disease 19 infection, Multiple organ failure losartan alone Angiotensin II AT-1 receptor antagonist, Angiotensin II receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of British Columbia Canadian Institutes of Health Research US, France, Belgium, Canada, Spain, Japan 2020-10-09 2021-06-30 ARBs CORONA II, H20-01984, NCT04606563 Phase 3 Clinical Recruiting 19 8 Months 1372 Andre Kalil, MD, Anish Mitra, MD, Antonio Torres, MD, Brent Winston, MD, David Maslove, MD, David Sweet, MD, Francois Lamontagne, MD, Gregory Haljan, MD, J. Matthew Luther, MD, James A Russell, MD, John Boyd, MD, John Marshall, MD, Karen Tran, MD, Keith Walley, MD, Lynda Lazosky, Matthew Cheng, MD, Mitchell Levy, MD, Omar Sharif, MD, Peter Birks, MD, Pierre Asfar, MD, Puneet Mann, Puneet Mann, MSc, Rahim Kachra, MD, Robert Fowler, MD, Santiago Perez, MD, Steve Reynolds, MD, Taka-aki Nakada, MD, Thierry Dugernier, MD, Vicente Corrales-Medina, MD, Xavier Wittebol, MD 2020-11-03
VOCOVID: An open-label, single-center, investigator-initiated, exploratory trial to evaluate the safety and the antiviral effects of voclosporin versus tacrolimus in kidney transplant recipients (KTRs) with COVID-19 (SARS-CoV-2) Coronavirus disease 19 infection, Kidney transplantation voclosporin alone Calcineurin inhibitor, IL-2 receptor antagonist Aurinia Pharmaceuticals Inc Netherlands 2020-10-27 VOCOVID Phase Not Applicable Recruiting 1 20 Dr Aiko P.J. de Vries, Dr Y.K. Onno Teng 2020-10-30
Study to Find the Percentage of Cases Retaining COVID-19 IgG Antibodies 45 to 65 After They Have Tested Positive Coronavirus disease 19 infection ErbaLisa COVID-19 kit (Erba Corporate Services) alone, enzyme-linked immunosorbent assay alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Tata Main Hospital India 2020-07-01 2020-08-30 152473, NCT04605952 Phase Not Applicable Completed 1 1 Month 201 Dr.Deb Sanjay Nag 2020-11-03
Study of Nebulized Ampion for the Treatment of Adult COVID-19 Patients With Respiratory Distress Coronavirus disease 19 infection, Respiratory distress syndrome Ampion (intranasal, inflammation), Ampio/DMI Biosciences alone, standard of care alone Stem cell antigen-1 inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ampio Pharmaceuticals Inc US 2020-10-27 2021-03-31 AP-014, NCT04606784 Phase 1 Clinical Recruiting 1 5 Months 40 Ampio Pharmaceuticals, Inc, Ampio Pharmaceuticals, Inc. 2020-11-16
EQUINOX: A Study to Evaluate the Efficacy and Safety of Itolizumab in Subjects Hospitalized With COVID-19 Coronavirus disease 19 infection, Viral pneumonia itolizumab alone T-cell differentiation antigen CD6 inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Equillium Inc Biocon Ltd US, Colombia 2020-11-30 2021-06-30 EQ001-20-001, EQUINOX, NCT04605926 Phase 3 Clinical Not yet recruiting 2 7 Months 800 Ivor S. Douglas, M.D, Maple Fung, MD, Stephanie Leyva 2020-11-21
WEAICOR: Wearables to Investigate the Long Term Cardiovascular and Behavioral Impacts of COVID-19 Cardiovascular disease, Coronavirus disease 19 infection Biostrap wristband device alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tulane University US 2020-06-09 2022-06-30 2020-678, NCT04605965, WEAICOR Phase Not Applicable Recruiting 2 24 Months 100 Agnieska Drutel, PhD, Agnieszka Drutel, PhD, Agniezska Drutel, PhD, Arezu Bhatnagar, MD, MSCRM, Monique Rhodes, JD, Nassir Marrouche, MD 2020-11-04
AR0-CROWN: Effect of tenofovir / emtricitabine short course on viral clearance in outpatient SARS-CoV2 (COVID-19) infected patients Coronavirus disease 19 infection tenofovir disoproxil fumarate + emtricitabine (fixed dose), Gilead Sciences alone HIV-1 reverse transcriptase inhibitor, Nucleoside reverse transcriptase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) CHU de Caen France 2020-10-15 20-070, 2020-001867-94, AR0-CROWN Phase 3 Clinical Recruiting 1 180 Coordinator Investigator 2020-11-02
CYCLOVID: Evaluation of Alisporivir for the Treatment of Hospitalised Patients With Infections Due to SARS-CoV-2 (COVID-19) Coronavirus disease 19 infection alisporivir alone, standard of care alone Cytochrome P450 3A4 inhibitor, Peptidyl-prolyl cis-trans isomerase A inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris Debiopharm SA France 2020-11-01 2021-08-04 2020-002295-13, APHP200552, CYCLOVID, NCT04608214 Phase 2 Clinical Not yet recruiting 2 9 Months 100 Jean-Michel PAWLOTSKY, MD, PhD, Raphaël LEPEULE, MD 2020-11-04
NoCo-CoBio: Northern Colorado COVID-19 Biobank Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Colorado State University University of Colorado Health US 2020-07-08 2022-07-30 20-10063H, NCT04603677, NoCo-CoBio Phase Not Applicable Recruiting 4 24 Months 200 Bridget Baxter, Elizabeth P Ryan 2020-11-03
PSY HCW Kel: The Psychological Impacts of Covid-19 Pandemic and Its Associated Socio-demographic Characteristics Among Government Health Care Workers in Kelantan, Malaysia Coronavirus disease 19 infection, Psychiatric disorder Healthy volunteers accepted Jabatan Kesihatan Negeri Kelantan Malaysia 2020-11-01 2021-02-01 56611, NMRR-20-2306-56611, PSY HCW Kel Phase Not Applicable Status not specified 1 3 Months Dr Noor Hashimah binti abdullah, Dr Tiong Wen Ning 2020-10-30
Morbidity Post COVID-19 - Investigation and call to action Coronavirus disease 19 infection Spirometry alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Griffith University, Royal Brisbane & Women's Hospital Royal Brisbane & Womens Hospital Research Foundation Australia 2020-11-02 2021-07-30 ACTRN12620001114932p Phase Not Applicable Not yet recruiting 2 8 Months 200 Dr Jennifer Paratz 2020-11-06
SOBI: Anakinra, COVID-19, Cytokine Storm Coronavirus disease 19 infection, Respiratory failure, Systemic inflammatory response syndrome, Viral pneumonia anakinra alone Type I IL-1 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Weill Medical College of Cornell University Swedish Orphan Biovitrum AB US 2020-11-30 2022-02-28 20-07022396, NCT04603742, SOBI Phase 2 Clinical Not yet recruiting 1 15 Months 100 Iris Y Navarro-Millan, MD, MSPH 2020-11-04
Best larnyngoscopes for tracheal intubation in covid patient with intubation box Coronavirus disease 19 infection CMAC video laryngoscope alone Young Adults (18-44 yrs) All India Institute of Medical Sciences India 2020-11-04 CTRI/2020/10/028637 Phase 3 Clinical Not yet recruiting 1 100 Dr Balbir Kumar 2020-10-29
Covid-19 infection during pregnancy and its effect on the mother and baby Coronavirus disease 19 infection Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Christian Medical College and Hospital India 2020-11-01 CTRI/2020/10/028636 Phase Not Applicable Not yet recruiting 1 100 Kavita Mandrelle 2020-10-30