Last updated: Dec 12, 2020 - 02:00 GMT

Title Indication Intervention Actions PatientSelection Sponsor Collaborator Country StartDate EndDate Identifiers Phase Recruitment Status Sites Trial Duration Enrollment Count Contacts LastChanged
Ampligen in Chronic Fatigue Syndrome Chronic fatigue syndrome, Coronavirus disease 19 infection rintatolimod alone 2,5-Oligoadenylate synthetase stimulator, Interferon type I receptor agonist, Ribonuclease stimulator, TLR-3 agonist Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) AIM ImmunoTech Inc US AMP 511, NCT00215813 Phase 3 Clinical Recruiting 2 Ann Marie Coverly, Charles Lapp, MD, Charles W. Lapp, M.D., Daniel Peterson, M.D., Daniel Peterson, MD, Diane Young 2020-10-27
Blood changes in COVID-19 and it is influence Coronavirus disease 19 infection Beckman coulter DSX8 alone, COBAS 6500 alone, Sysmex CS 2400 alone Newborn Infants (up to 5 months) Sri Ramachandra Medical College, Hospital & Research institute India 2020-12-15 CTRI/2020/12/029671 Phase Not Applicable Not yet recruiting 0 800 Dr Febe Renjitha Suman, Dr JAYALAKSHMI B 2020-12-11
MICHELLE: Medically Ill Hospitalized Patients for COVID-19 Thrombosis Extended Prophylaxis With Rivaroxaban Therapy Coronavirus disease 19 infection, Thromboembolism, Viral pneumonia rivaroxaban alone Factor Xa antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Science Valley Research Institute Bayer AG Brazil 2020-10-16 2021-06-30 21589 MICHELLE TRIAL, MICHELLE, NCT04662684 Phase 3 Clinical Recruiting 0 8 Months 320 Eduardo Ramacciotti,, Eduardo Ramacciotti, MD, Ph.D, Eduardo Ramacciotti, MD, PhD, Leandro Agati, PhD 2020-12-11
Requirements analysis for a robotic assistive system to support and promote the autonomy of people with neuromuscular diseases Coronavirus disease 19 infection, Neuromuscular disease, Spinal muscular atrophy robotic assistance system alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Charite Universitaetsmedizin Berlin Deutsche Forschungsgemeinschaft (DFG), German Federal Ministry of Education and Research Germany 2020-09-16 DRKS00022534, EA4/150/20, U1111-1257-2583 Phase Not Applicable Recruiting 0 15 Cornelia Eicher 2020-12-11
Analyzing impact of pre-existing comorbidities on serious adverse outcomes in hospitalised COVID19 patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Max Smart Super Speciality Hospital India 2020-12-21 CTRI/2020/12/029744 Phase Not Applicable Not yet recruiting 0 128 Nandani Gulati 2020-12-11
ReDiCare: Relieving Distressed Caregivers: A Pragmatic Trial Coronavirus disease 19 infection care counseling alone, stepped care model alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Friedrich Schiller University of Jena, Robert Bosch Hospital AOK Baden-Württemberg, Deutsche Forschungsgemeinschaft (DFG), German Federal Ministry of Education and Research Germany 2018-05-15 DRKS00014593, FSV 18/08, ReDiCare Phase 3 Clinical No longer recruiting 0 504 Gabriele Wilz, Klaus Pfeiffer 2020-12-11
Analyzing effect of COVID 19 on mental health of frontline healthcare workers Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Max Smart Super Speciality Hospital India 2020-12-21 CTRI/2020/12/029743 Phase Not Applicable Not yet recruiting 0 246 Nandani Gulati 2020-12-11
A clincial trial of PneumoBlast for the trreatment of covid-19 in Brazil Coronavirus disease 19 infection PneumoBlast alone R4D Biotech Phase Not Applicable Planned 0 2020-12-11
A Study to Assess the Safety and Efficacy of CoroQuil-Zn 500 in Comparison to the Standard of Care for the Treatment of Mild to Moderate COVID-19 Coronavirus disease 19 infection CoroQuil-Zn alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Remedium Therapeutics Private Limited India 2020-12-15 CTRI/2020/12/029735 Phase 3 Clinical Not yet recruiting 0 100 Disha Shetty, Dr Sambashiva AC, Mr Mallikarjun Bidari 2020-12-11
A Clinical Safety Study on AT-100 in Treating Adults With Severe COVID-19 Infection Coronavirus disease 19 infection AT-100, Airway alone Lung surfactant associated protein D modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Airway Therapeutics LLC US 2021-01-31 2021-07-31 AT-100/002, NCT04659122 Phase 1b Clinical Not yet recruiting 0 6 Months 9 Marc O. Salzberg, MD, Neil P. Mills, BS, Paul S. Kingma, MD, PhD, Robert D. Hite, MD 2020-12-11
To Assess CT Chest finding of Post-covid Pneumonia Patient Coronavirus disease 19 infection, Pulmonary fibrosis, Viral pneumonia Chest CT scan alone, pirfenidone alone, prednisolone alone, pirfenidone plus prednisolone PDGF receptor antagonist, TGF beta receptor antagonist, p38 MAP kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) GMERS Medical College and Hospital India 2020-12-25 CTRI/2020/12/029733 Phase Not Applicable Not yet recruiting 0 50 Dr Anand Patel, Dr Nil Patel 2020-12-11
SOUNDS: Surgery and Lung Ultrasound in SARS-CoV-2 Infection Coronavirus disease 19 infection lung ultrasound alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundacion Clinica Valle del Lili Colombia 2020-05-08 2021-11-30 1601, NCT04661631, SOUNDS Phase Not Applicable Recruiting 0 18 Months 451 Alberto F Garcia, MDMSc 2020-12-11
Aerobic Training Versus Cognitive Behavioral Therapy in Management of Anxiety Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression aerobic exercises alone, cognitive behavioral therapy alone Female, Young Adults (18-44 yrs) Cairo University Egypt 2020-12-10 2021-02-25 12-2020, NCT04662021 Phase Not Applicable Recruiting 0 2 Months 40 Marwa Eid 2020-12-11
Health After Covid-19 in Tyrol Coronavirus disease 19 infection Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Medizinische Universität Innsbruck Claudiana Landesfachhochschule Austria 2020-09-30 2021-12-31 20200928-2379, NCT04661462 Phase Not Applicable Recruiting 0 15 Months 1000 Judith Löffler-Ragg 2020-12-11
A Study of Auxora in Patients With Critical COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia CM-4620 alone Ca2+ release activated Ca2+ channel 1 inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) CalciMedica Inc Northwestern University US 2020-12-31 2021-04-30 CM4620-205, NCT04661540 Phase 2 Clinical Not yet recruiting 0 4 Months 36 Richard Wunderink, MD, Richard Wunderlink, MD, Sudarshan Hebbar 2020-12-11
MONIREA: Use of RDS MultiSense in Post-ICU Patients in the COVID-19 Era Coronavirus disease 19 infection, Viral pneumonia MultiSense strip alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopitaux Universitaires de Strasbourg Rhythm Diagnostics Systems Inc France 2021-06-30 2022-06-30 20-004, MONIREA, NCT04661423 Phase Not Applicable Not yet recruiting 0 12 Months 60 Armelle TAKEDA, PhD, Julien POTTECHER, MD, PhD 2020-12-11
Reward Re-Training: A New Treatment to Address Reward Imbalance During the COVID-19 Pandemic Coronavirus disease 19 infection, Eating disorder reward re-training group therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Drexel University The National Institute of Mental Health US 2020-12-01 2022-03-30 2009008088, NCT04661410, R01MH122392-01S1 Phase Not Applicable Recruiting 0 15 Months 60 Research Coordinator 2020-12-11
FENOC: Fenofibrate for Patients With COVID-19 Requiring Hospitalization Coronavirus disease 19 infection fenofibrate (micronized), Fournier/Abbott alone, usual medical care alone Lipoprotein lipase stimulator, PPAR alpha agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hebrew University of Jerusalem Barzilai medical center Israel 2020-12-13 2021-12-01 0105-20-BRZ, FENOC, NCT04661930 Phase 3 Clinical Recruiting 0 11 Months 50 Avner Ehrlich, Mahram Nassar, MD, Shlomo Mayaan, MD, Yaakov Nahmias, PhD 2020-12-11
COVEPICARDIO: The Cognitive and sport Virtual EPIC Training Study for Cardiovascular Diseases Atherosclerosis, Atrial fibrillation, Coronavirus disease 19 infection, Diastolic heart failure, Systolic heart failure home-based cognitive training alone, physical exercise training alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Montreal Heart Institute Canada 2020-05-18 2022-12-01 COVEPICARDIO, ICM 2020-2785, NCT04661189 Phase Not Applicable Recruiting 0 30 Months 118 Florent Besnier, PhD, Louis Bherer, PhD 2020-12-11
A Study to Assess the Effectiveness of ImmuRich in COVID-19 Positive Patients Coronavirus disease 19 infection ImmuRich capsule (RPS Biotech Private Limited) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) RPS BIOTECH PVT LTD India 2020-12-15 CTRI/2020/12/029713 Phase 2 Clinical Not yet recruiting 0 100 DR MANOJ RUNGHE 2020-12-11
Koa Family Study: A Community-Based Intervention to Improve Health and Well-Being (KFS) Coronavirus disease 19 infection, Obesity Whole health program alone, health messages texting alone, mind-body-spirit intervention alone, social media support alone, tree planting alone Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) University of California Davis US 2021-01-31 2021-09-30 1668154, Koa Family Study, NCT04662593 Phase Not Applicable Not yet recruiting 0 8 Months 120 Crystie Dao, MS, Desiree Backman, DrPH, MS, RD, Neal Kohatsu, MD, MPH 2020-12-11
CAPNOR: Impact of Molecular Testing on Improved Diagnosis, Treatment and Management of CAP Coronavirus disease 19 infection, Pneumonia BioFire FilmArray Pneumonia plus platform (Biomerieux) alone, active feedback alone, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry alone, microbiological biochemical testing alone, real-time PCR alone, ultra-rapid molecular testing alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Haukeland University Hospital Copenhagen University, Drammen Hospital, Quadram Institute Bioscience, Rigshospitalet, Universitair Medisch Centrum Utrecht, University Of Southampton, University of Bergen Norway 2020-09-25 2022-12-31 CAPNOR, HAUKELANDUH_31935, NCT04660084 Phase Not Applicable Recruiting 0 27 Months 1060 Elling Ulvestad, MD PhD, Harleen Grewal, MD PhD, Rune Bjørneklett, MD PhD 2020-12-11
ASCO: ASCO Survey on COVID-19 in Oncology Registry Cancer, Coronavirus disease 19 infection American Society of Clinical Oncology US 2020-04-19 2022-12-31 ASCO, NCT04659135, PRO00014181 Phase Not Applicable Recruiting 0 32 Months 2000 Adam Al Douri, Alexander Spira, Amol Rao, Angie Dunbar, Anthony Franklin, Ashley Jones, Brandon Bennett, Brenda Groff, Charu Aggarwal, Christopher Laman, Christopher McNair, Christy Hughes, Danielle Geiger, Dara Richie, Debbie Vidlak, Elizabeth Garrett-Mayer, PhD, Eric Clayton, Eric Small, Gina Cravey, Hailey Johnson, Ihab Azab, Jamie Harper, Jen H Williams, MA, Jennifer Orlando, Karen Sceniak, Kathryn Mileham, Kelly Hattery, Kent Disney, Kevin Mills, Kimberly Maher, Latha Subramanian, Lisa Kosmacek, Lori Backus, Lynn Harrison, Mandy Joosten, Margaret Mazzone, Mary Amos, Matthew Carter, Matthew Korzeniewski, Melanie Meehan, Michelle Britto, Milan Sheth, Nancy Studier, Nicole Fowler, Peter Yu, Philip Lammers, Poornima Saha, R. Donald Harvey, PharmD, Richard L Schilsky, MD, Rosie Drulias, Rudi Ross, Sandra Guy, Scott Baker, Stephanie McClellan, Suanna S Bruinooge, MPH, Susan Knight, Susan Moore, Tara Barker, Thomas Semrad, Thorvardur Halfdanarson, Tina Inverso, Uzma Rizwan, Wasif Saif, Williams Wood 2020-12-11
Adolescents With COVID-19/MIS-C at HCFMUSP Coronavirus disease 19 infection home-based exercise training program alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) University of Sao Paulo Fundacao de Amparo a Pesquisa do Estado Sao Paulo, Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo Brazil 2020-09-24 2021-04-30 37460620.8.0000.0068, NCT04659486 Phase Not Applicable Recruiting 0 7 Months 100 Bruno Gualano, Clovis Silva, PhD 2020-12-11
Phase I/II Randomized, Dose Escalation Study to Evaluate the Safety and Antiviral Activity of the RD-X19 Device in SARS-CoV-2 Infected Individuals With Uncomplicated COVID-19 Coronavirus disease 19 infection RD-X19 alone, electromagnetic treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) EmitBio Inc. KNOW Bio LLC US 2020-11-18 2021-04-30 EB-P12-01, NCT04662671 Phase 1/Phase 2 Clinical Recruiting 0 5 Months 60 EB-P12-01 Study Director 2020-12-11
ACP-COVID: Advance Care Planning: Communicating With Outpatients for Vital Informed Decision Coronavirus disease 19 infection ACP Decisions Video Program alone, VitalTalk communication skills training alone, intervention training alone, medical record review alone Healthy volunteers accepted, Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dana-Farber Cancer Institute Inc National Institute on Aging US 2021-02-28 2021-04-30 20-600, ACP-COVID, NCT04660422, UH3AG060626-03S1 Phase Not Applicable Recruiting 0 2 Months 13150 Edith Burns, MD, James A. Tulsky, MD 2020-12-11
NOSOCOVID: Nosocomial COVID-19 in ICU Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) CHU De Nantes France 2020-09-01 2021-03-01 MR_NOSOCOVID, NCT04659356, NOSOCOVID Phase Not Applicable Recruiting 0 6 Months 600 BOURIGAULT Celine, MD, CANET Emmanuel, PHd, GARRET Charlotte, GARRET Charlotte, MD, LASCARROU Jean-Baptiste, MD, LEMARIE Jeremy, MD, MARTIN Maelle, MD, REIGNIER Jean, PHd 2020-12-11
Tele-RehaB: Pulmonary Tele-Rehabilitation Program: Feasibility and Safety Study Coronavirus disease 19 infection, Respiratory disease pulmonary telerehabilitation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec Fondation IUCPQ Canada 2020-12-31 2022-01-31 21983, NCT04658979, Tele-RehaB Phase Not Applicable Recruiting 0 13 Months 30 Didier Saey, Ph.D, Didier Saey, PhD, Jany Harvey, M.Sc. 2020-12-11
Factors Affecting Mortality in Critical Patients Admitted to Intensive Care Unit Due to COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital Turkey 2020-03-22 2020-12-08 NCT04659876, SEPTEMBER 11, 2020: 550 Phase Not Applicable Completed 0 8 Months 445 Osman Uzundere 2020-12-11
Combination therapy trial in COVID-19 patients Coronavirus disease 19 infection antibiotic treatment alone, anticoagulant treatment alone, antiviral treatment alone, sitagliptin alone, spironolactone alone, supplement intake alone, Variable regimens including dexamethasone , sitagliptin , spironolactone Aldosterone antagonist, Dipeptidyl peptidase IV inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Boushehr University of Medical Sciences Iran 2020-12-05 IR.BPUMS.REC.1399.140, IRCT20201003048904N2 Phase 2 Clinical Recruiting 0 200 Farhad Abbasi, Farzan Azodi, Gholamreza Khamisipour 2020-12-11
Cancer Within a Pandemic: A Telemental Health Intervention Anxiety disorder, Cancer, Coronavirus disease 19 infection, Depression online support group test alone, questionnaires alone, telemental health session alone Young Adults (18-44 yrs) Wake Forest University Health Sciences, US National Cancer Institute US 2021-02-28 2021-07-31 IRB00070150, NCT04659993, P30CA012197, WFBCCC01520 Phase Not Applicable Not yet recruiting 0 5 Months 15 Katie Duckworth, Ph.D, Katie Duckworth, PhD, Study Coordinator 2020-12-11
The mechanism of COVID-19 associated coagulopathy: a prospective, cohort study Blood clotting disorder, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tohoku University Japan Agency for Medical Research and Development Japan 2020-11-09 UMIN000042717 Phase Not Applicable Recruiting 0 100 Koji Saito, Yudai Iwasaki 2020-12-11
COVID-19 Infection among Healthcare Workers Coronavirus disease 19 infection Ministry of Health, Malaysia Malaysia 2020-12-14 2021-03-13 57584, NMRR-20-2648-57584 Phase Not Applicable Status not specified 0 3 Months Dr Abdul Aziz Harith 2020-12-11
COVID-19 pandemic and breast cancer management: An observational clinical study from Pakistan Breast tumor, Coronavirus disease 19 infection breast cancer surgery alone, neoadjuvant/systemic chemotherapy alone, telecommunication alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Aga khan University Aga Khan University Hospital karachi Pakistan 2020-03-14 2020-10-03 2020-5418-14043, DRKS00023807 Phase Not Applicable Completed 0 6 Months 112 Dua Jabeen, Narmeen Asif 2020-12-11
Spanish Survey on Third Wave of COVID-19 Coronavirus disease 19 infection Healthy volunteers accepted Universidad De Salamanca Spain 2020-12-09 2020-12-20 COVIDSAL01/2020, NCT04659473 Phase Not Applicable Not yet recruiting 0 1000 Beatriz M Bermejo-Gil, Professor, Fátima Pérez-Robledo, Doctor, Fátima Pérez-Robledo, Professor, Inés Llamas-Ramos, Doctor, Inés Llamas-Ramos, Professor, Juan L Sánchez-González, Professor, Rocío Llamas-Ramos, Professor 2020-12-11
A randomized, double-blind, placebo-controlled Phase II Clinical Trial to evaluate the safety and efficacy of a combination treatment of two drugs, and the best supportive care for patients with moderate and severe COVID-19 in a hospitalized setting Coronavirus disease 19 infection combination of two drugs alone Venn Life Sciences Phase 2 Clinical Status not specified 0 200 2020-12-11
Evaluation of Aerosol in a Dental Clinic Coronavirus disease 19 infection external evacuation device alone, extraoral vacuum aspirator alone, high volume evacuation suction device alone, hydrogen peroxide alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Texas Health Science Center Houston US 2020-12-01 2022-12-01 HSC-DB-20-1017, NCT04659928 Phase 4 Clinical Not yet recruiting 0 24 Months 50 Aaron Glick, DDS, FAGD, FICOI, D.ABDSM 2020-12-10
CORONADO: Circulating Tumor Protein Quantification Capillary Blood COVID Coronavirus disease 19 infection, Multiple myeloma, Plasma cell dyscrasia at-home blood sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institute of Cancer Research UK The Royal Marsden NHS Trust UK 2021-01-15 2021-10-01 CCR5361, CORONADO, NCT04659252 Phase Not Applicable Not yet recruiting 0 8 Months 70 Chloe Burrows, Haemato-oncology Research Team, Kevin Boyd 2020-12-10
A trial to evaluate Covid-19 vaccine for the prevention of Covid-19 Coronavirus disease 19 infection Covid-19 vaccine, VLP Therapeutics LLC alone VLP Therapeutics LLC National Center For Global Health & Medicine, National Institute of Biomedical Innovation, Oita University, Osaka City University Japan Phase Not Applicable Planned 0 2020-12-10
RIC as an Adjunct Therapy for Severe COVID-19 Disease: a Prospective, Randomized, Pilot Study Coronavirus disease 19 infection, Ischemia, Viral pneumonia remote ischemic conditioning alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) St Michaels Hospital Canadian Department of National Defence Canada 2020-12-15 2021-09-01 1.4, NCT04659460 Phase Not Applicable Not yet recruiting 0 8 Months 30 Sandy Trpcic 2020-12-11
Thyroid Function Tests and Status of Thyroid Autoantibodies in Patients With Covid Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bezmialem Vakif University Turkey 2020-09-01 2020-12-07 06122020, NCT04659200 Phase Not Applicable Recruiting 0 3 Months 20 Aysegul Yabacı, Research, Didem Ertorul, Dr, Sabahattin Destek, Sabahattin Destek, Associate Professor 2020-12-11
Hyperpolarized 129-Xe MRI of Survivors of COVID-19 Coronavirus disease 19 infection 129-Xe MRI alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Kansas Medical Center US 2021-01-01 2021-12-31 00146646, NCT04659707 Phase 1 Clinical Not yet recruiting 0 12 Months 20 Peter J Niedbalski, PhD, Peter J. Niedbalski 2020-12-11
A first global investigator-initiated phase-2 clinical trial in Mexico for camostat mesilate being developed as COVID-19 treatment Coronavirus disease 19 infection repurposed camostat mesilate (oral, COVID-19), Daewoong/Institut Pasteur Korea/Korea Institute of Radiological and Medical Sciences alone Serine protease inhibitor, Transmembrane serine protease 2 inhibitor, Trypsin inhibitor Daewoong Pharmaceutical Co Ltd, Institut Pasteur Korea, Instituto Nacional de Ciencias Medicas y Nutricion, Korea Institute of Radiological and Medical Sciences Mexico 2020-12-09 Phase 2 Clinical Status not specified 0 2020-12-10
Study Evaluating Safety, Tolerability and Efficacy of Allocetra-OTS in Patients With COVID-19 Coronavirus disease 19 infection Allocetra alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Enlivex Therapeutics Ltd 2021-03-31 2022-03-31 ENX-CL-03-001, NCT04659304 Phase 1b Clinical Not yet recruiting 0 12 Months 50 Lior Binder, Odelia Ben Shitrit, MBA, Oren Hershkovitz, PhD 2020-12-11
An observational study to evaluate the impact of COVID-19 on children with cystic fibrosis Coronavirus disease 19 infection, Cystic fibrosis Cystic Fibrosis Foundation Phase Not Applicable Status not specified 0 105 2020-12-10
Clinical Assessment of Insulin Fast Dissolving Film in Treatment of Post Infection Anosmia Coronavirus disease 19 infection, Dysomia insulin alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Deraya University Minia University Egypt 2020-12-01 2021-01-15 NCT04657809, S85INSU23FDF Phase 2 Clinical No longer recruiting 0 1 Month 40 Soad Ali, Soad Mohamed 2020-12-11
ASPEN-COVID-19: Assessing Safety, Hospitalization and Efficacy of rNAPc2 in COVID-19 Blood clotting disorder, Coronavirus disease 19 infection AB-201, Arca Biopharma alone Factor VII antagonist, Tissue factor inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) ARCA Biopharma Inc Colorado Prevention Center, University of Colorado US 2020-12-04 2021-05-31 ASPEN-COVID-19, NAPc-201/301, NCT04655586 Phase 2/Phase 3 Clinical Not yet recruiting 0 5 Months 100 Dr Michael Bristow, Jennifer Meriwether, Marc Bonaca, MD, MPH 2020-12-10
The Effect of Omega-3 Supplements on the Serum Levels of ACE/ACE2 Ratio as a Potential Key in Cardiovascular Disease and COVID-19: A Randomized Clinical Trial in the COVID-19 Uninfected Jordanian People Cardiovascular disease, Coronavirus disease 19 infection omega-3 fatty acids alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Applied Science Private University Jordan 2020-12-05 2021-03-30 2020-PHA-22, NCT04658433 Phase Not Applicable Recruiting 0 3 Months 100 Luai z Hasoun, PhD, Mahmoud S Abu-Samak, PhD, Mahmoud Suleiman Abu-Samak, Sara M Daboul, MSC, Sara M Daboul, Master, luai z Hasoun, PhD 2020-12-11
OXYCOVID: Liberal use of oxygen in early stage of COVID-19 patients Coronavirus disease 19 infection oxygen alone, usual care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) AIIMS Jodhpur India 2020-12-16 CTRI/2020/12/029614, OXYCOVID Phase 2 Clinical Not yet recruiting 0 80 Dr Mahendra Kumar Garg 2020-12-11
GARDEN: Glenzocimab in SARS-Cov-2 Acute Respiratory Distress Syndrome Related to COVID-19 Coronavirus disease 19 infection, Dyspnea, Respiratory distress syndrome glenzocimab alone Platelet glycoprotein VI inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Acticor Biotech 2020-12-31 2021-07-31 2020-002733-15, ACT-CS-006, GARDEN, NCT04659109 Phase 2 Clinical Not yet recruiting 0 7 Months 60 Andrea Comenducci, MD, Yannick Pletan, MD 2020-12-11
CORONA Germany: Clinical Outcome and Risk in Hospitalized COVID-19 Patients: A Registry From Germany Arterial thrombosis, Cancer, Cardiac arrest, Cardiac failure, Cardiogenic shock, Coronary artery disease, Coronavirus disease 19 infection, Heart arrhythmia, Ischemic stroke, Lung embolism, Myocardial infarction, Myocarditis, Phlebothrombosis Asklepios Proresearch Asklepios Kliniken Hamburg GmbH Germany 2020-03-26 2021-06-07 #3871, CORONA Germany, NCT04659187 Phase Not Applicable Recruiting 0 14 Months 4000 Axel Stang, Prof. MD, Bertholt Bein, Prof. MD, Christian Glöckner, MD, Christoph U Herborn, Prof. MD, Dirk Arnold, Prof. MD, Hans-Peter Hauber, MD, Jürgen Behr, Prof. MD, Klaus Herrlinger, Prof. MD, Lorenz Nowak, MD, Martin Bergmann, Prof. MD, Melanie Gunawardene, MD, Nele Gessler, MD, Rüdiger Schreiber, MD, Sebastian Wirtz, MD, Stephan Willems, Prof. MD, Thomas Hölting, MD, Tino Schnitgerhans, MD, Ulrich-Frank Pape, MD 2020-12-11
A study on efficacy of combined Chinese and Western medicine and follow-up of long-term prognosis in patients with novel coronavirus pneumonia (COVID-19) Carbohydrate metabolism disorder, Cardiovascular disease, Cerebrovascular disease, Coronavirus disease 19 infection, Renal disease, Respiratory disease, Viral pneumonia different treatment regimens (combined Chinese and Western medicine) alone Public Health Clinical Center of Chengdu China 2021-01-10 2021-05-30 ChiCTR2000040770, ChiMCTR2000004148 Phase Not Applicable Recruiting 0 4 Months 300 Chen Qing, Wu Guihui 2020-12-11
Clinical and Hematological Phenotypes in Long COVID Coronavirus disease 19 infection, Inflammatory disease peripheral blood immunophenotyping alone, serum biochemistry analysis alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) HCA International UK 2020-12-31 2021-06-30 LCV, NCT04659889 Phase Not Applicable Recruiting 0 6 Months 100 Dr Paul Glynne, Mr Glynne, Dr, Natasha Tahmasebi, Miss, Paul Glynne, Dr, Rajeev Gupta, Dr, Vanya Gant, Dr 2020-12-10
Optimized TCM diagnosis and treatment plan for novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Traditional Chinese Medicine alone, conventional treatment alone, integrated Chinese and conventional medicine alone Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Beijing Hospital of Traditional Chinese Medicine affiliated to Capital Medical University Beijing science and Technology Commission China 2020-12-01 2021-01-31 ChiCTR2000040765, ChiMCTR2000004147 Phase Not Applicable Recruiting 0 2 Months 700 Liu Qingquan, Su Rui 2020-12-11
A survey of the impact on mental health and therapies in patients with chronic disease during the pandemic of COVID-19 Anxiety disorder, Coronavirus disease 19 infection, Depression Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The First Affiliated Hospital of college of medicine Zhejiang University China 2020-10-10 ChiCTR2000040729 Phase Not Applicable Recruiting 0 800 Minglan Wu 2020-12-11
FACE COVID-19: Femoral Fractures and COVID-19 Coronavirus disease 19 infection, Lower limb fracture Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Istituto Ortopedico Galeazzi Spa Italy 2020-11-14 2020-12-31 FACE COVID-19, FACE COVID-19, NCT04657510 Phase Not Applicable Recruiting 0 1 Month 140 Francesca Villa, MSc, Francesco Luceri, MD, Giuseppe M Peretti, MD, Ilaria Morelli, MD, Riccardo Giorgino, MD 2020-12-11
COVID-PRICE: COVID-19 Pregnancy Related Immunological, Clinical and Epidemiological Factors and Perinatal Outcomes Coronavirus disease 19 infection Female Thomas Jefferson University The Nemours Foundation US 2020-11-17 2022-06-30 20F.1043, COVID-PRICE, NCT04659759 Phase Not Applicable Recruiting 0 19 Months 50 Rupsa C Boelig, MD 2020-12-11
Effectiveness of internet psychotherapy in reduction of anxiety/depression of infertile women Anxiety disorder, Coronavirus disease 19 infection, Depression online cognitive behavioral therapy alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) National Institute for Medical Research Development Iran 2020-12-05 IR.NIMAD.REC.1398.174, IRCT20110228005931N9 Phase Not Applicable Recruiting 0 60 Dr. Farzan Kheirkhah, Dr. Farzan Kheyrkhah, Dr. Zahra Basirat, mahboobe faramarzi, shiva shafie rizi 2020-12-11
Expanded Access to Zofin (Organicell Flow) for Patients With COVID-19 Coronavirus disease 19 infection Zofin (Organicell Flow) alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Organicell Regenerative Medicine bioRASI LLC 19881-EA, NCT04657406 Phase Not Applicable Recruiting 0 Mari Mitrani, MD, PhD 2020-12-10
Expanded Access Protocol on Bone Marrow Mesenchymal Stem Cell Derived Extracellular Vesicle Infusion Treatment for Patients With COVID-19 Associated ARDS Adult respiratory distress syndrome, Coronavirus disease 19 infection, Hypoxia, Respiratory failure ExoFlo alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Direct Biologics LLC DB-EAP-001, NCT04657458 Phase Not Applicable Recruiting 0 Heidi Moran 2020-12-11
A Study of FOY-305 in Patients With SARS-Cov-2 Infection (COVID-19) Coronavirus disease 19 infection camostat mesylate alone Serine protease inhibitor, Transmembrane serine protease 2 inhibitor, Trypsin inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ono Pharmaceutical Co Ltd Japan 2020-11-09 2021-05-31 FOY305-01, NCT04657497 Phase 3 Clinical Recruiting 0 6 Months 110 Naoyuki Komura 2020-12-11
COFATSOM: Fatigue and Sleep in Patients With COVID-19 Coronavirus disease 19 infection, Fatigue Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) University Hospital, Bordeaux 2020-12-05 2021-06-30 CHUBX 2020/52, COFATSOM, NCT04657419 Phase Not Applicable Not yet recruiting 0 6 Months 720 Pierre PHILIP, Pr 2020-12-10
COVIDTEL: Parental Compliance After Telephone Triage Advice During and After Confinement During the COVID Epidemic in France Coronavirus disease 19 infection formalized telephone triage advice alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) Fondation Lenval France 2020-12-31 2021-03-31 20-HPNCL-03, COVIDTEL, NCT04656444 Phase Not Applicable Not yet recruiting 0 3 Months 250 Antoine TRAN, Antoine TRAN, MD 2020-12-11
The Impact of COVID-19 on Surgical Practice in Jordan During the Second Outbreak: A Survey Coronavirus disease 19 infection Healthy volunteers accepted Yarmouk University Jordan 2020-11-01 2020-11-10 ChiCTR2000040633 Phase Not Applicable No longer recruiting 0 60 Raed M Ennab 2020-12-11
UNITED: At-Home Infusion Using Bamlanivimab in Participants With Mild to Moderate COVID-19 Coronavirus disease 19 infection bamlanivimab alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Aged Adults (65-79 yrs), Elderly Adults (80 and over) UnitedHealth Group Inc Eli Lilly & Co, Optum Inc US 2020-12-31 2021-05-31 2020-0081_, NCT04639479, NCT04656691, UNITED Phase 4 Clinical Not yet recruiting 0 5 Months 7500 Dan Griffin, MD, PHD, Michelle Tanner, BA, Tracy Ziolek, MS 2020-12-11
Effect Of Covid-19 Disease In Smell And Taste Of Patients With Mild, Moderate Or Severe Symptomatology Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Ioannina General Hospital of Ioannina G. Hatzikosta Greece 2020-11-17 2021-06-30 931/17-11-2020, NCT04657445 Phase Not Applicable Recruiting 0 7 Months 100 AIKATERINI LIANOU, SPECIALIST, ANGELOS LIONTOS, CONSULTANT, ATHINA ZARACHI, SPECIALIST, CHARALAMPOS MILIONIS, PROFESSOR, ELEFTHERIOS KLOURAS, RESIDENT, IOANNIS KASTANIOUDAKIS, PROFESSOR, IOANNIS KOMNOS, CONSULTANT, Liontos Angelos, MARIA MICHALI, SPECIALIST, angelos liontos, consultant 2020-12-10
COVIDVacImpac: Impact of the COVID-19 Pandemic on Vaccination Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Montpellier France 2020-11-01 2021-05-30 COVIDVacImpac, NCT04657263, RECHMPL20_0655 Phase Not Applicable Recruiting 0 6 Months 500 Ariane Sultan, Ariane Sultan, MD, Cyril BREUKER, Cyril BREUKER, PharmD,Phd, cyril BREUKER 2020-12-11
A phase III trial to evaluate CoviSafe for the detection of COVID-19 Coronavirus disease 19 infection CoviSafe alone Kannaba Technologies Inc Therma Bright Inc Phase 3 Clinical Planned 0 2020-12-10
A phase II trial to evaluate CoviSafe for the detection of COVID-19 Coronavirus disease 19 infection CoviSafe alone Kannaba Technologies Inc Therma Bright Inc Phase 2 Clinical Planned 0 2020-12-09
A phase I trial to evaluate CoviSafe for the detection of COVID-19 Coronavirus disease 19 infection CoviSafe alone Kannaba Technologies Inc, Therma Bright Inc Phase 1 Clinical Planned 0 2020-12-09
Brief Mindfulness-Based Intervention to Improve Psychological Wellbeing Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Psychiatric disorder virtual brief mindfulness session alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Imam Abdulrahman Bin Faisal University Saudi Arabia 2020-07-07 2020-09-05 MINDFULLNESS during COVID19, Mindfullness during a pandemic, NCT04656626 Phase Not Applicable Completed 0 1 Month 146 Amani al-qurni, BOARD 2020-12-11
Disinfection & cross infection tests on sports equipment in covid-19 Coronavirus disease 19 infection a cross-infection test alone, disinfectants alone, test gloves alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) St Marianna University School of Medicine Japan 2020-10-28 UMIN000042270 Phase Not Applicable Not yet recruiting 0 41 Hiroto Fujiya, Kanaka Yatabe 2020-12-10
NgT-NAFOGA(NATION) Study: Phase I clinical trial to investigate the safety, tolerability and pharmacokinetics of NewGenNafamostat in healthy male subjects Coronavirus disease 19 infection nafamostat (COVID-19 infection), Institut Pasteur Korea alone Serine protease inhibitor, Transmembrane serine protease 2 inhibitor Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) NewGen Therapeutics Inc NewGen Therapeutics Inc South Korea 2020-12-05 KCT0005647, NgT-NAFOGA(NATION), NgT-NAFOGA(NATION) Study Phase 1 Clinical Not yet recruiting 0 32 Hyun Chul Kim, Seung Hwan Lee 2020-12-10
MORPH-II: Revisiting A Mobile Intervention to Reduce Pain and Improve Health Coronavirus disease 19 infection, Pain caloric restriction intervention alone, movement restriction intervention alone Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Wake Forest University US 2021-01-31 2022-10-31 IRB00023965, MORPH-II, NCT04655001 Phase Not Applicable Not yet recruiting 0 21 Months 100 Amber Brooks, MD, Charlotte Crotts, BS, Jason Fanning, PhD 2020-12-10
DIRECTOR: Dynamics of the Immune Response to COVID-19/Infection by SARS-CoV-2 Coronavirus disease 19 infection, Respiratory tract infection Healthy volunteers accepted, Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitat des Saarlandes MeMed Diagnostics Ltd Germany 2020-12-02 2021-08-31 109/20, DIRECTOR, NCT04655521 Phase Not Applicable Recruiting 0 8 Months 300 Cihan Papan, MD 2020-12-11
Urine Alkalinization to Prevent AKI in COVID-19 Coronavirus disease 19 infection, Renal injury sodium bicarbonate alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Guy's & St Thomas' Hospital NHS Trust UK 2021-02-01 2022-03-30 283852, NCT04655716 Phase 3 Clinical Not yet recruiting 0 13 Months 80 Marlies Ostermann 2020-12-11
Hospitalization or Outpatient Management of Patients With SARS-CoV-2 Infection - Revised HOME-CoV Score Study Coronavirus disease 19 infection revised HOME-CoV score alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Angers France 2020-12-08 2021-06-08 2020-A03067-32, NCT04657471 Phase Not Applicable Not yet recruiting 0 6 Months 1300 Alexandre GHUYSEN, Andrea PENALOZA, Anyhony CHAUVIN, Caroline SOULIE, Christian BRICE, Coralie CAYEUX, David DALL'ACQUA, Delphine DOUILLET, Emmanuel MONTASSIER, Esma OUMMAMAR, Florent FREMY, Francis COUTURAUD, Frédéric BALEN, Henri Hani KARAM, Henrinjatovo ANDRIANJAFY, Julie PERNET, Kasarra BEN HAMMOUDA, Laure ABENSUR VUILLAUME, Marc ANDRONIKOF, Marc NOIZET, Mathieu VIOLEAU, Medhi TAALBA, Meïssa KARE, Mustapha SEBBANE, Nicolas PESCHANSKI, Ombeline SUSONG, Pascal BISSOLOKELE, Pierre-Clément THIEBAUD, Romain BLONDET, SCHMIDT Jeannot, Sonja CURAC, Stéphane GENNAI, Séverine GOSSELIN, Yann-Erick CLAESSENS 2020-12-10
Multiple Interactive With Nutrition and Exercise Strategies in Frailty Cancer Patients Coronavirus disease 19 infection, Muscle weakness cycle exercise alone, online nutrition consultation alone, routine nutrition consultation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tzu Chi University Taiwan 2020-11-01 2023-11-30 NCT04654637, TCU-CHHUANG Phase Not Applicable Recruiting 0 37 Months 128 Chu Hou Huang, PhD, Chun Hou Huang, Chun Hou Huang, Phd 2020-12-10
SARS-CoV-2/COVID-19 Prevalence Study Coronavirus disease 19 infection Healthy volunteers accepted, Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) COVID-19 Prevention Network US, Puerto Rico 2020-12-15 2021-03-30 COVPN 5002, NCT04658121 Phase Not Applicable Not yet recruiting 0 3 Months 3920 Ayana Moore, PhD, Jessica Justman, MD, Laura Mkumba 2020-12-10
Impact of Postoperative Telemedicine Visit versus In-person Visit on Patient Satisfaction During the COVID-19 Pandemic: A Prospective, Randomized Trial Coronavirus disease 19 infection Telemedicine visit alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cedars-Sinai Medical Center US 2020-09-28 2021-06-30 NCT04652674, STUDY00000944 Phase Not Applicable Recruiting 0 9 Months 70 Karen Zaghiyan, MD, Lucille Yao, MD, Phillip Fleshner, MD 2020-12-10
COLDSTER: Comparison of Two Corticosteroid Regimens for Post-COVID Diffuse Lung Disease Coronavirus disease 19 infection, Lung disease, Viral pneumonia prednisolone alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Postgraduate Institute of Medical Education and Research India 2020-12-10 2021-12-09 COLDSTER, INT/IEC/2020/SPL-1528, NCT04657484 Phase 2 Clinical Recruiting 0 12 Months 100 Ritesh Agarwal, MD, DM, Sahajal Dhooria, Sahajal Dhooria, MD, DM 2020-12-10
Edtech-HPV: A Community Approach Using Education and Technology to Increase HPV Vaccination Coronavirus disease 19 infection, Papillomavirus infection Text messaging reminder alone, parental HPV vaccine education alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Memorial Sloan-Kettering Cancer Center US 2017-06-28 2022-06-30 17-336, Edtech-HPV, NCT03209713 Phase Not Applicable Recruiting 0 60 Months 800 Abraham Aragones, MD, MS, Ester Corpuz, Eva Moya, PhD, Francesca Gany, MD, MS, Rebeca Aceves Zaragoza 2020-12-10
A clinical trial of peginterferon alfa-2b follow-on-biologic, Zydus-Cadila for the treatment of Coronavirus disease 19 infection Coronavirus disease 19 infection Zydus Cadila Healthcare Ltd US Phase Not Applicable Planned 0 2020-12-09
Reducing Food Insecurity During COVID-19 Coronavirus disease 19 infection Fresh Connect produce prescription program alone, grocery store gift cards alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Boston Medical Center Corp Krupp Family Foundation, Patient Centered Outcome Research Institute, US Department of Agriculture, Waldron Charitable Fund US 2021-01-31 2022-10-31 6007145, H-41052, NCT04652596, PENDING Phase Not Applicable Not yet recruiting 0 21 Months 250 Erin Ashe, MPH, Jocelyn Antonio, BS, Michael Silverstein, MD MPH, Michael Silverstein, MD, MPH 2020-12-09
STOP: Preference-based Tools for Smoking Cessation Among Disadvantaged Smokers, a Pragmatic, Randomized, Controlled Trial Coronavirus disease 19 infection, Nicotine dependence STOP smoking cessation intervention alone, drug prescription alone, e-liquid alone, electronic cigarette alone, free smoking aid delivery alone, nicotine alone, nicotine replacement therapy alone, routine care alone, short didactic video watching alone, smoking cessation advice alone Nicotinic acetylcholine receptor agonist Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Société de Formation Thérapeutique du Généraliste INSERM, National Cancer Institute, France France 2020-12-15 2023-12-15 NCT04654585, STOP, STOP-001 Phase 2 Clinical Not yet recruiting 0 36 Months 528 André Nguyen Van Nhieu, MD, André Soares, MD, Anne Kerharo-Nicolas, MD, Anne-Laurence Le Faou, MD, Anne-Marie Ruppert, MD, Boyer Laurent, MD, Carole Plaussu, MD, Cécile Roche Dominguez, MD, Fabienne El-Khoury, Fabienne El-Khoury Lesueur, PhD, Ghislaine Hacke Mela, MD, Gladys Ibanez, MD, Kebir Oussama, MD, Kinouani Shérazade, MD, Laura Piras, MD, Maria Melchior, PhD, Marion Adler, MD, Mathilde Roze, MD, Michel Cadart, MD 2020-12-11
PRINCESS: Pronation in COVID-19 Patients Undergoing Non Invasive Respiratory Support Coronavirus disease 19 infection, Viral pneumonia awake prone position alone, non invasive respiratory support alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Modena and Reggio Emilia Italy 2020-03-01 2020-11-30 NCT04649658, PRINCESS, UMODENAREGGIO10 Phase Not Applicable Completed 0 9 Months 93 Roberto Tonelli 2020-12-10
COVID-RIC1: Seroprevalence Study of CoV-2-SARS Infection in Patients With Chronic Inflammatory Rheumatic Diseases Coronavirus disease 19 infection, Psoriatic arthritis, Rheumatoid arthritis, Spondylarthritis routine care alone, serological testing alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Montpellier France 2020-12-01 2021-07-30 COVID-RIC1, NCT04655612, RECHMPL20_0624 Phase Not Applicable Recruiting 0 7 Months 5000 Jacques MOREL, MD, PhD, Jacques Morel, MD, PhD, Thao Pham, MD, PhD 2020-12-10
Impact of COVID-19 Pandemic on Out-of-Pocket Costs, Lost Wages, and Unemployment in Patients With Breast Cancer Undergoing Breast Surgery Breast tumor, Coronavirus disease 19 infection mastectomy alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) MD Anderson Cancer Center National Cancer Institute US 2019-05-21 2022-03-31 NCI-2019-07463, NCT04169542, PA18-1077 Phase Not Applicable Recruiting 0 34 Months 600 Anaeze Offodile, Elizabeth FitzSullivan, Makesha V. Miggins, Richard A. Ehlers 2020-12-10
Cov-activity: Physical Activity Program Implementation in Hospitalized Positive Covid-19 Older Adults Coronavirus disease 19 infection physical activity program alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire de Toulouse France 2020-11-01 2021-12-31 Cov-activity, NCT04647682, RC31/20/0145 Phase Not Applicable Recruiting 0 14 Months 30 Laurine ANDRE, MD 2020-12-10
SPUTNIK-UAE: A Phase III Clinical Trial of the Immunogenicity and Safety of the Gam-COVID-Vac Vaccine Against COVID-19 in the UAE Coronavirus disease 19 infection Sputnik V alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gamalei Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation Collaborator PDC-CRO United Arab Emirates, Saudi Arabia 2020-12-31 2021-12-31 06-GAM-COVID-VAC-2020, NCT04656613, SPUTNIK-UAE Phase 3 Clinical Recruiting 0 12 Months 1000 Ahmed Al Hammadi, Mohamed Mostafa 2020-12-10
Addressing Anxiety in 2 to 3-Year Olds: A Pilot, Intervention Study Anxiety disorder, Coronavirus disease 19 infection, Generalized anxiety disorder, Phobia, Social phobia being brave protocol based-cognitive behavioral therapy alone Healthy volunteers accepted, Infants (6-23 months), Preschool Children (2-5 yrs) Massachusetts General Hospital US 2019-09-27 2022-09-01 2018P000376, NCT04039243 Phase Not Applicable Recruiting 0 35 Months 90 Dina Hirshfeld-Becker, PhD, Jordan Holmen, BA 2020-12-10
A case-report study of a newborn infant with congenital factor X deficiency and COVID-19 infection Coronavirus disease 19 infection frozen plasma alone, tranexamic acid alone Female Shahid Beheshti University of Medical Sciences Phase Not Applicable Status not specified 0 1 2020-12-10
COVID-HIGH: HFNT Versus COT in COVID-19 Coronavirus disease 19 infection, Hypoxia, Respiratory failure, Respiratory tract infection, Viral pneumonia High Flow Nasal Therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone Palermo Azienda Ospedaliero - Universitaria Policlinico - Vittorio Emanuele Italy 2021-01-10 2022-03-01 1TH DEC 2020, COVID-HIGH, NCT04655638 Phase Not Applicable Not yet recruiting 0 13 Months 364 Alberto Noto, Alessio Mattei, Andrea Cortegiani, Andrea Cortegiani, MD, Annalisa Carlucci, Antonino Giarratano, Cesare Gregoretti, Claudia Crimi, Claudia Crimi, MD, Enrico Clini, Nicola Scichilone, Raffaele Scala 2020-12-09
Effectiveness of ICU diaries on satisfaction of family members of COVID-19 patients in the ICU Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Sapporo Medical University School of Medicine Japan 2020-09-01 UMIN000042681 Phase Not Applicable No longer recruiting 0 4 JUNPEI HARUNA 2020-12-08
MAPPING-V: Malaysian Public Preferences and Willingness to pay for Covid-19 Vaccination: A Discrete Choice Experiment Coronavirus disease 19 infection Covid-19 Vaccine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institutes of Health Malaysia Malaysia 2021-01-01 2021-12-31 57377, MAPPING-V, NMRR-20-2633-57377 Phase Not Applicable Not yet recruiting 0 12 Months MISS TEH HOON SHIEN 2020-12-11
nCoV-19 in elderly Coronavirus disease 19 infection Healthy volunteers accepted Hospital Kuala Lumpur Malaysia 2020-04-24 2020-05-24 54825, NMRR-20-2620-54825 Phase Not Applicable Status not specified 0 1 Month Dr Lee Yoong Wah 2020-12-11
RLX0120: Trial to study efficacy and safety of two doses of raloxifene in adult paucisymptomatic COVID-19 patients Coronavirus disease 19 infection raloxifene alone Estrogen receptor modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dompe Farmaceutici SpA Italy 2020-10-31 2020-003936-25, RLX0120, RLX0120 Phase 2/Phase 3 Clinical Recruiting 1 150 Flavio Mantelli 2020-12-09
Physical Activity During Covid-19 Lockdown Coronavirus disease 19 infection Physical Activity alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Tengku Ampuan Afzan, University Malaya Medical Centre Malaysia 2020-12-02 2021-03-17 55434, NMRR-20-2607-55434 Phase Not Applicable Status not specified 2 3 Months Dr Lim Zhuang Li, Dr. Choong Wai Kwong 2020-12-08
Phase II/III Study of COVID-19 DNA Vaccine (AG-0302-COVID19) Coronavirus disease 19 infection AG-0301-COVID19 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) AnGes MG Inc Japan Agency for Medical Research and Development Japan 2020-11-23 2022-03-31 AG0302-COVID19-JN-02, NCT04655625 Phase 2/Phase 3 Clinical Recruiting 0 16 Months 500 AnGes, Inc. Clinical Development 2020-12-10
COVID-VAC: Factors Influencing the Potential Acceptance of a Covid-19 Vaccine Among Healthcare Workers in a District Hosipital in Manjung, Perak Coronavirus disease 19 infection COVID-19 vaccine alone Healthy volunteers accepted HOSPITAL SERI MANJUNG Malaysia 2020-12-07 2021-01-31 57315, COVID-VAC, NMRR-20-2589-57315 Phase Not Applicable Not yet recruiting 0 1 Month 384 Chiew Shoen Chuen, Dr Lee Li Yuan 2020-12-11
COVID-19 Outbreak Management Coronavirus disease 19 infection JABATAN KESIHATAN NEGERI TERENGGANU Malaysia 2020-12-15 2021-02-28 56487, NMRR-20-2584-56487 Phase Not Applicable Status not specified 0 2 Months AHMAD FUAD BIN OMAR, Dr Goh Soo Ning 2020-12-11
COVIDEYE: Prevalence of SARS-CoV-2 Genome in Tears of Asymptomatic and Moderately Symptomatic COVID-19 Patients Coronavirus disease 19 infection PCR alone, conjunctival swab test alone, nasopharyngeal swab test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-12-31 2021-12-31 2020-A02996-33, APHP201268, COVIDEYE, NCT04654325 Phase Not Applicable Not yet recruiting 1 12 Months 1280 Antoine ROUSSEAU, PhD, Antoine Rousseau, PhD, Christelle Vauloup-Fellous, PhD 2020-12-09
Efficacy of prebiotic products on admitted patients with Covid-19 Coronavirus disease 19 infection probiotic intake alone, hydroxychloroquine plus remdesivir COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Shaheed Beheshti Medical University Iran 2020-09-22 IR.SBMU.RETECH.REC.1399.562, IRCT20161206031255N4 Phase 3 Clinical Recruiting 1 60 Afshin Zerghi, Roshanak Mokaberinejad 2020-12-09
Bromhexine hydrochloride for prophylaxis against COVID-19 Coronavirus disease 19 infection bromhexine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shaheed Beheshti Medical University Iran 2020-08-22 IR.SBMU.PHARMACY.REC.1399.247, IRCT20120703010178N22 Phase 3 Clinical Recruiting 0 1050 Hassan Yazdan Panah, Mohammad Sistanizad, Omid Moradi, Shadi Ziaie 2020-12-08
Clinical Outcome of Patients With COVID-19 Pneumonia Treated With Corticosteroids and Colchicine Coronavirus disease 19 infection, Viral pneumonia dexamethasone alone, colchicine plus dexamethasone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Clínica Medellín - Comprometidos con tu Salud Colombia 2020-03-20 2020-08-20 04-2020, NCT04654416 Phase Not Applicable Completed 1 5 Months 301 Miguel Alejandro Pinzón 2020-12-09
A multi-center, double-blind, placebo-controlled, adaptive design, phase III clinical trial to evaluate the efficacy and safety of fostamatinib in adult, hospitalized COVID-19 patients Coronavirus disease 19 infection fostamatinib disodium alone Syk tyrosine kinase inhibitor Rigel Pharmaceuticals Inc 2020-12-31 Phase 3 Clinical Planned 0 2020-12-08
Prevalence of burnout, its associated factors among Dr and nurse of JB DHO during COVID-19 pandemic Coronavirus disease 19 infection Healthy volunteers accepted Universiti Sains Malaysia Malaysia 2021-01-01 2021-05-31 57271, NMRR-20-2579-57271 Phase Not Applicable Not yet recruiting 1 5 Months Dr NUR SUJAIHAH BINTI HANAFI 2020-12-09
A large-scale surveillance study of OneDraw Blood Collection Device to assess the prevalence of previous infection with COVID-19 Coronavirus disease 19 infection OneDraw device alone Drawbridge Health Inc, University of Cambridge UK Phase Not Applicable Recruiting 1 4000 Professor Nick Wareham 2020-12-08
Awareness, Knowledge and Attitudes of Obstetricians towards the use of Telemedicine in Antenatal Care: A Cross-sectional study in a Tertiary Government Hospital in the Philippines during the COVID-19 Pandemic Coronavirus disease 19 infection Telemedicine alone Philippine General Hospital Philippines 2020-10-20 2020-11-30 PHRR201201-003180 Phase Not Applicable Completed 1 1 Month Dominique Joyce M. Concepcion, Izabelle Julienne Figueras-Prieto, Regina Rosario M. Panlilio 2020-12-08
COVID-19 Cure Using Integrative Treatment Coronavirus disease 19 infection Integrative treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Knowledge Research and Innovation Center, Pakistan 2020-03-17 2020-06-30 ChiCTR2000040632 Phase 1 Clinical Completed 1 3 Months 34 Muhammad Yahya Qureshi, Umber Nawaz 2020-12-09
Treatment With Pirfenidone for COVID-19 Related Severe ARDS Coronavirus disease 19 infection, Respiratory distress syndrome pirfenidone alone, standard of care alone PDGF receptor antagonist, TGF beta receptor antagonist, p38 MAP kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Soroka University Medical Center Roche Holding AG Israel 2020-11-08 2021-12-31 NCT04653831, SCRC20007 Phase 2 Clinical Recruiting 1 13 Months 100 Ori Galante, MD, Yasmeen Abu Fraiha, Yasmeen Abu Fraiha, MD 2020-12-09
Efficacy of barley water (Hordeum vulgare) in clinical outcome of COVID-19 patients Coronavirus disease 19 infection, Viral pneumonia barley water intake alone, current medication alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shiraz University of Medical Sciences Iran 2020-11-15 IR.SUMS.REC.1399.216, IRCT20150830023823N3 Phase 2 Clinical Recruiting 1 50 Abbas Rezaianzadeh, Ali Tavakoli 2020-12-10
To compare the effect of lying in face down position along with oxygen therapy given through high-flow nasal cannula device versus lying face down with oxygen given by non-rebreathing face mask in COVID-19 patients Coronavirus disease 19 infection, Hypoxia, Respiratory failure awake prone positioning alone, high-flow nasal cannula alone, oxygen alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences Patna India 2020-12-15 CTRI/2020/12/029587 Phase 2 Clinical Not yet recruiting 1 60 Rajnish Kumar 2020-12-09
Effects of PPE among Healthcare Workers Coronavirus disease 19 infection, Psychiatric disorder personal protective equipment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sri Ramachandra Medical College, Hospital & Research institute Sri Ramachandra University India 2020-12-15 CTRI/2020/12/029584 Phase Not Applicable Not yet recruiting 1 150 Dr Swathy Moorthy, DrSPThiagarajan 2020-12-07
CADE: Cardiac Assessment After Covid-19 Disease in Elite Altheltic Population Coronavirus disease 19 infection, Heart injury MRI alone, echocardiography alone, electrocardiogram alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) University Hospital, Montpellier Centre Hospitalier Universitaire de Nimes, Centre Hospitalier de Perpignan, Clinique du Millénaire, Rennes University Hospital, ligue nationale de Basket France 2020-04-01 2021-01-01 CADE, NCT04653857, RECHMPL20_0648 Phase Not Applicable No longer recruiting 1 9 Months 250 Christophe HEDON, MD, Stéphane CADE, MD 2020-12-09
Effectiveness of Unani add-on therapy in preventing the disease severity of COVID-19 infection Coronavirus disease 19 infection Variable regimens including Behidana, Unnab and Sapistan-unani decoction , Joshanda tea , Tiryaq-e-Arba , azithromycin , hydroxychloroquine , vitamin C , zinc Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Central Council for Research in Unani Medicine Ministry of Ayush India 2020-12-04 CTRI/2020/12/029575 Phase 3 Clinical Not yet recruiting 1 100 Dr Jugal Kishore, Dr Rohit Kumar, Dr Tamanna Nazli, Prof Jugal Kishore 2020-12-09
Study of the safety of hyperimmune bovine milk and colostrum against COVID-19 Coronavirus disease 19 infection bovine Colostrum plus bovine milk Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Isfahan University Isfahan Oil Refinery Iran 2020-11-10 2020-11-25 IR.MUI.MED.REC.1399.672, IRCT20200927048849N1 Phase 1 Clinical Completed 1 40 Hassan Niliahmadabadi, Rasoul Roknizadeh, Somayeh Sadeghi 2020-12-08
A study of cyclophosphamide outcomes in patients with COVID-19 Coronavirus disease 19 infection, End stage renal disease, Respiratory distress syndrome, Vasculitis cyclophosphamide plus prednisone Metropolitan Hospital Center Phase Not Applicable Status not specified 0 3 2020-12-07
GraphealNpas: Feasibility and Analytical Performance of TestNPass (IVDMD) for COVID-19 Diagnosis on Saliva Sample Coronavirus disease 19 infection TestNPass diagnotic medical device (Grapheal SAS) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Grenoble Grapheal SAS France 2020-12-15 2021-03-15 2020-A03087-32, 38RC20.378, GraphealNpas, NCT04654442 Phase Not Applicable Not yet recruiting 1 3 Months 60 Benjamin Némoz, MD, Benjamin Némoz, Némoz, Marion Le Maréchal, MD, Pierre AUDOIN, MS 2020-12-09
NIVHOC: A clinical trial to compare the effect of non-invasive ventilation with high-flow nasal oxygen therapy versus only high flow nasal oxygen therapy in COVID 19 patients with respiratory failure Coronavirus disease 19 infection, Respiratory failure face mask alone, non-invasive ventilation based high flow nasal oxygen therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences Patna India 2020-12-12 CTRI/2020/12/029585, NIVHOC Phase Not Applicable Not yet recruiting 1 100 Kunal Singh 2020-12-09
ROCD: A study of kidney Problems with covid 19 in admitted patients at a teritiary care hospital Coronavirus disease 19 infection, Renal disease Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Yenepoya Medical college India 2020-12-21 CTRI/2020/12/029581, ROCD Phase Not Applicable Not yet recruiting 1 300 Dr Santhosh Pai, Dr Santhosh pai 2020-12-09
Various Blood Parameters Affecting outcome in ICU Patients Coronavirus disease 19 infection, Vitamin D deficiency Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) JSS University India 2020-12-15 CTRI/2020/12/029586 Phase Not Applicable Not yet recruiting 1 150 DR AKSHAY, DR Rajalakshmi R 2020-12-09
Aerosol Particle Concentrations Among Different Oxygen Devices for Spontaneous Breathing Patients With Tracheostomy Coronavirus disease 19 infection, Respiratory disease Airvo2 (Fisher and Paykel Healthcare Ltd) alone, high-flow high humidity oxygen therapy alone, tracheostomy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rush University Medical Center US 2021-01-31 2021-05-31 HFOT-TRACH-AEROSOL, NCT04654754 Phase Not Applicable Not yet recruiting 1 4 Months 10 Jie Li, Jie Li, PhD 2020-12-07
Study of AffloVest in At-Risk Respiratory Patients During COVID-19 Pandemic Chronic obstructive pulmonary disease, Coronavirus disease 19 infection, Cough Afflovest device alone, Standard Care alone, digital thermometer alone, high frequency chest wall oscillation (HFCWO) therapy alone, pulse oximeter alone, spirometer alone, telehealth training alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mount Sinai Medical Center International Biophysics Corporation, SPARK Healthcare US 2020-12-31 2021-11-30 GCO 20-2667, ISMMS-AFF-20, NCT04654481 Phase Not Applicable Recruiting 1 11 Months 30 Elinor L Schwind, MS, Patricia Walker, MD, Teresa Demarco, PTA 2020-12-09
Serial sero-epidemiological surveillance study to monitor the trend of SARS-CoV-2, Dengue and Chikungunya infection transmission in the Vellore Demographic Health Surveillance System (HDSS) Chikungunya virus infection, Coronavirus disease 19 infection, Dengue virus infection neutralization assay alone Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Christian Medical College, Vellore, India Biotechnology Industry Research Assistance Council, National BioPharma Mission India 2020-12-10 CTRI/2020/12/029564 Phase Not Applicable Not yet recruiting 1 5000 Winsley Rose 2020-12-08
ReCOV: RT-PCR Database Analysis for COVID-19 Infections and Re-infection Coronavirus disease 19 infection RT-PCR alone University Hospital, Montpellier Centre Hospitalier Universitaire de Nimes, Centre National de la Recherche Scientifique (CNRS), Laboratoire Pasteur-Cerba, MIVEGEC, MPL Analysis Laboratoires France 2020-02-01 2021-03-30 NCT04653844, RECHMPL20_0640, ReCOV Phase Not Applicable No longer recruiting 1 13 Months 7000000 Vincent Foulongne, PhD 2020-12-09
A case report study of severe encephalopathy or focal brain lesions in children with multisystem inflammatory syndrome associated with COVID-19 Brain disease, Coronavirus disease 19 infection, Inflammatory disease Variable regimens including IV immunoglobulin , anakinra , methylprednisolone Type I IL-1 receptor antagonist Male, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Columbia University Irving Medical Center Phase Not Applicable Status not specified 0 1 2020-12-07
AtemNHK: Effects of Integrative Medicine on Infectious Respiratory Diseases Including COVID-19 Coronavirus disease 19 infection, Respiratory tract infection protective lifestyle intervention alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Charite University Germany 2020-12-31 2021-12-31 ATEMNHK, AtemNHK, NCT04653727 Phase Not Applicable Not yet recruiting 1 12 Months 3000 Andreas Michalsen 2020-12-09
Evaluation of prophylaxis induced by ivermectin in populations exposed to COVID-19 patients Coronavirus disease 19 infection ivermectin alone Chloride channel modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Akam Tejarat Fartak Farasoo Iran 2020-11-30 IR.QUMS.REC.1399.261, IRCT20200408046987N3 Phase 3 Clinical Recruiting 3 800 Abbas Allami, Alireza Mehralian, Morteza Shakhsi Niaee, Nematollah Gheibi, fatemeh samieerad 2020-12-08
Effect of GRAPEX in treatment of COVID-19 Coronavirus disease 19 infection Grapex alone, Standard country protocol drug therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Abadan University of Medical Sciences Iran 2021-01-08 IR.ABADANUMS.REC.1399.098, IRCT20200921048783N1 Phase 3 Clinical Not yet recruiting 1 80 Hoda Mojiri-Forushani, Hoda Mojjiri-Forushani, Sara Mobarak 2020-12-08
A phase II study to evaluate PIC1-01 for the treatment of patients with hypoxic ischemic encephalopathy (HIE) Brain hypoxia-ischemia, Coronavirus disease 19 infection PIC1-01 alone Complement C1s subcomponent inhibitor ReAlta Life Sciences Inc Europe Phase 2 Clinical Planned 0 2020-12-07
The effect of Helichrysum pseudoplicatum syrup on clinical manifestations of patients with COVID-19 Coronavirus disease 19 infection, Respiratory tract infection Helichrysum pseudoplicatum syrup (Shahid Beheshti, Arak University of Medical Sciences) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Arak University of Medical Sciences and Health Services Iran 2020-05-18 IR.ARAKMU.REC.1399.003, IRCT20180610040049N6 Phase 3 Clinical No longer recruiting 1 60 Alireza Kamali, Hosein Sarmadian, Mohammad KamaliNejad, Seied Amirhosein Latifi 2020-12-08
A pivotal, phase II/III clinical trial to evaluate SCB-2019 in combination with Dynavax’s advanced CpG 1018 adjuvant plus alum for the prevention of SARS-CoV-2 infection Coronavirus disease 19 infection Variable regimens including CpG 1018 adjuvant , SCB-2019 , alum COVID19 Spike glycoprotein modulator Clover Biopharmaceuticals AUS Pty Ltd 2021-06-30 Phase 2/Phase 3 Clinical Planned 0 2020-12-07
Serological investigations of blood donors from the city and area around Magdeburg for antibodies against SARS-CoV-2 (COVID-19) Coronavirus disease 19 infection serological examination alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Institut fUr Medizinische Mikrobiologie und Krankenhaushygiene Institut fur Sozialmedizin und Gesundheitssystemforschung, Ministerium für Wirtschaft, Wissenschaft und Digitalisierung des Landes Sachsen-Anhalt Germany 2021-01-15 163/20, DRKS00023263 Phase 4 Clinical Not yet recruiting 1 4500 Heuft Hans-Gert, Stephan Kramer 2020-12-08
A retrospective, case series study to describe clinical outcomes associated with tocilizumab compared with those not receiving tocilizumab in critically ill patients with severe COVID-19 Coronavirus disease 19 infection tocilizumab alone Atrium Health Phase Not Applicable Status not specified 0 49 2020-12-07
A follow-up study of long-term prognosis in patients with novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Xi'an Children's Hospital China 2020-02-02 2021-05-31 ChiCTR2000040628 Phase Not Applicable Recruiting 1 15 Months 430 Guo Yaling, Xu You, Yang Mingb, Yang Puye 2020-12-07
Novel coronavirus pneumonia (COVID-19) treated with different antiviral regimens: a medical records based study for analysis of therapeutic effect and length of stay of hospitalization Coronavirus disease 19 infection hormone therapy alone, Variable regimens including Lianhua Qingwen , abidol , interferon , oseltamivir , ribavirin Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) People's Hospital of Shapingba District, Chongqing City China 2020-12-01 2022-11-30 2020SQKWLH016, ChiCTR2000040571 Phase Not Applicable Not yet recruiting 1 24 Months 180 Huang Zi Yang 2020-12-07
Impact of COVID-19 pandemic on post graduate medical trainees in India Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Post Graduate Institute of Dental Sciences (PGIMS) India 2020-12-06 BREC/20/204, CTRI/2020/12/029515 Phase Not Applicable Not yet recruiting 1 1000 Jyoti Khanna 2020-12-07
An exploratory, phase II, physician-initiated clinical trial investigating the efficacy and safety of TM-5614 in patients with novel coronavirus pneumonia Coronavirus disease 19 infection, Viral pneumonia TM-5614 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Japan Agency for Medical Research and Development Japan 2020-07-20 2021-01-31 jRCT2021200018 Phase 2 Clinical Recruiting 1 6 Months 30 Fumio Sakamaki, Harigae Hideo, Hideo Zhang, Hisatoshi Sugiura, Isao Ito, Keisuke Tomii, Koichiro Asano, Sakurako Tajiri, Yasunari Miyazaki 2020-12-07
MeDiCo- health Study: Eating habits during the Covid-19 pandemic Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Technical University of Munich EIT Food iVZW, Personalized nutrition and vitamins - LOEWI Germany 2020-12-03 655/20 S, DRKS00022514, MeDiCo- health Study Phase Not Applicable Not yet recruiting 1 200 Laura Mengel, Thomas Skurk 2020-12-07
CHDR2044: Healthy volunteers blood sampling Coronavirus disease 19 infection flow cytometry alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Leyden Laboratories BV Netherlands 2020-11-03 2021-01-31 CHDR2044, NL75505.058.20, NL9045 Phase Not Applicable Not yet recruiting 1 2 Months 20 I.M.C. de Visser-Kamerling 2020-12-08
DF in COVID19: A Single-Arm Safety and Feasibility Study of Defibrotide for the Treatment of Severe COVID-19 Coronavirus disease 19 infection, Viral pneumonia defibrotide (iv, veno-occlusive disease), Gentium alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Brigham & Women's Hospital Jazz Pharmaceuticals plc US 2021-01-01 2023-11-01 2020P003203, DF in COVID19, NCT04652115 Phase 2 Clinical Not yet recruiting 1 34 Months 42 Paul G Richardson, MD, Paul G. Richardson 2020-12-08
Exploratory research on severity indicators for COVID-19 patients Coronavirus disease 19 infection, Viral pneumonia Body motion sensor alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Japan Agency for Medical Research and Development Japan 2020-07-30 2020-12-31 jRCT1052200041 Phase Not Applicable Not yet recruiting 1 5 Months 40 Eiji Asanoi, Naho Fujiwara, Shigeru Miyagawa, Sho Saito, Yoshiki Sawa, Yukio Abe, sawa Yoshiki 2020-12-07
Effect of the COVID-19 Public Health Crisis on the Mental Health and Physical Well-Being of Cancer Patients, the Coping With COVID Study Acute stress disorder, Coronavirus disease 19 infection, Psychiatric disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) MD Anderson Cancer Center National Cancer Institute US 2020-07-13 2021-03-31 2020-0451, NCI-2020-06556, NCT04652505 Phase Not Applicable Recruiting 1 8 Months 700 Tamara E Lacourt, Tamara E. Lacourt 2020-12-08
CoronaVac3CL: Efficacy, Safety, and Immunogenicity of an Inactivated Vaccine Against COVID-19 in High Infection Risk Adults Coronavirus disease 19 infection CoronaVac alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Pontificia Universidad Catolica De Chile Ministry of Health, Sinovac Research & Development Co Ltd Chile 2020-11-27 2022-03-31 200708006, CoronaVac3CL, NCT04651790 Phase 3 Clinical Recruiting 1 16 Months 2300 Alvaro Rojas, MD, Carolina Iturriaga, Nurse, Katia Abarca, MD, María Soledad Navarrete, Nurse 2020-12-09
An observational, single-center study to evaluate the prevalence of major bleeding events in patients with COVID-19 receiving intensive thromboprophylaxis Bleeding, Coronavirus disease 19 infection enoxaparin alone, heparin alone Università della Svizzera italiana Switzerland Phase Not Applicable Status not specified 1 270 2020-12-04
WAYRA: Home-based Respiratory Physiotherapy and Telephone-Based Psychological Support in Severe COVID-19 Patients Coronavirus disease 19 infection home-based respiratory physiotherapy alone, telephone-based psychological support alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Universidad Peruana Cayetano Heredia Johns Hopkins University, London School of Hygiene and Tropical Medicine Peru 2020-10-26 2021-03-30 202852, NCT04649736, WAYRA Phase Not Applicable Recruiting 1 5 Months 108 Anderson N. Soriano-Moreno, MD, Andres G Lescano, PhD, MHS, Germán Málaga, MD, MSc, Stella M Hartinger, MSc, PhD, William Checkley, MD, PhD 2020-12-07
CovExc: Muscular Rehabilitation by Eccentric Exercise After Severe COVID-19 Infection Coronavirus disease 19 infection rehabilitation by eccentric exercises alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Clermont-Ferrand GIRCI Auvergne Rhône-Alpes, Ministry of Health, France France 2020-06-05 2021-12-05 2020-A01201-38, CovExc, NCT04649086, PHRCI 2020 COSTE (COVEXC) Phase Not Applicable Recruiting 5 18 Months 120 Dominic PERENNOU, MD, PhD, Emmanuel COUDEYRE, MD, PhD, Emmanuelle CHALEAT-VALAYER, MD, PhD, Lise Laclautre, PharmD, Léonard FEASSON, MD, PhD, Nicolas COSTE, MD, MSc, Paul ORNETTI, MD, PhD 2020-12-07
Packaging and Disseminating the JOIN for ME Program in Low-Income Settings Coronavirus disease 19 infection, Obesity JOIN for ME program alone Healthy volunteers accepted, Children (6-12 yrs) Miriam Hospital Brandeis University, Brown University, Tufts University, University of North Carolina US 2021-01-31 2023-02-28 5U18DP006429-02, NCT04647760 Phase Not Applicable Not yet recruiting 1 25 Months 128 Andrea M Grenga, BA, Elissa Jelalian, PhD 2020-12-07
SHYCOV: Silent Hypoxia and Awake Proning in COVID-19 Patients Coronavirus disease 19 infection, Hypoxia physiotherapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ostfold Hospital Trust Norway 2020-11-30 2021-12-31 NCT04647747, SHYCOV, SHYCOV2020 Phase Not Applicable Not yet recruiting 1 13 Months 40 Hans Joakim Myklebust-Hansen 2020-12-07
Rapid Development and Implementation of a Remote ECG-monitored, Prospective, Randomized Clinical Trial During a Pandemic: Hydroxychloroquine Prophylaxis in COVID-19 Household Contacts Coronavirus disease 19 infection hydroxychloroquine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bryn Mawr Hospital Sharpe-Strumia Foundation US 2020-05-27 2020-11-15 BM02332, NCT04652648 Phase 4 Clinical Completed 3 5 Months 54 Luciano kapelusznik 2020-12-07
PCR Cycle Threshold Values and COVID-19 Outcomes Coronavirus disease 19 infection real-time polymerase chain reaction alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospitals of North Midlands NHS Trust UK 2020-11-24 2021-03-31 286389, NCT04651413 Phase Not Applicable Recruiting 1 4 Months 800 Keira Watts, Robert Bowler, Robert J Bowler, Timothy Kemp 2020-12-08
The Protective Potential of Exercise Training on the Cardiopulmonary Morbidity After COVID-19 Coronavirus disease 19 infection high intensity interval training alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rigshospitalet Denmark 2021-01-01 2021-12-31 H-20033733 V.2, NCT04647734 Phase Not Applicable Not yet recruiting 1 12 Months 40 Regitse Christensen, MD, PhD, Ronan Berg, DMSc, MD 2020-12-08
COMBO: Camostat With Bicalutamide for COVID-19 Coronavirus disease 19 infection Standard of care alone, camostat mesylate alone, bicalutamide plus camostat mesylate Androgen receptor antagonist, Serine protease inhibitor, Transmembrane serine protease 2 inhibitor, Trypsin inhibitor Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sidney Kimmel Comprehensive Cancer Center US 2021-01-31 2023-01-31 COMBO, COV2005, IRB00254142, NCT04652765 Phase 1 Clinical Not yet recruiting 1 24 Months 60 Aliya Lalji, MD, Catherine H Marshall, MD/MPH 2020-12-08
LYT-100 in Post-acute COVID-19 Respiratory Disease Coronavirus disease 19 infection, Fibrosis, Inflammatory disease, Viral pneumonia deupirfenidone alone PDGF receptor antagonist, TGF beta receptor antagonist, p38 MAP kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) PureTech Health Plc Clinipace Worldwide, Novotech (Australia) Pty Ltd Romania, US 2020-12-31 2021-12-31 LYT-100-2020-02, NCT04652518 Phase 2 Clinical Recruiting 2 12 Months 168 Adrian Streinu-Cercel, MD, PhD, Barry Sigal, MD, FCCP, Heather Paden, Site Coordinator, Toby Maher, MD 2020-12-11
Testing the effectiveness of almitrine bismesylate in the treatment of COVID-19 Coronavirus disease 19 infection, Hypoxia, Viral pneumonia almitrine bismesylate alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Oxford LifeArc UK 2020-04-30 2021-09-30 2020-002567-57, CPMS 47241, IRAS 282381, ISRCTN11713182 Phase 2 Clinical Recruiting 3 17 Months 116 Dr Talbot 2020-12-08
FSC19-KN: Single-Center, Prospective, Controlled, Follow-up Study of COVID-19 Patients District Konstanz Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hegau-Bodensee-Klinikum Deutsche Forschungsgemeinschaft (DFG), German Federal Ministry of Education and Research Germany 2021-01-01 20-1020, DRKS00022409, FSC19-KN Phase Not Applicable Not yet recruiting 1 400 Marc Kollum 2020-12-08
Observational, Retrospective Study to Evaluate Coagulation Changes and the Influence of Antithrombin III Treatment in Patients With Severe COVID-19 Infection Blood clotting disorder, Coronavirus disease 19 infection antithrombin III alone Octapharma AG Austria, Germany, France 2020-10-19 2021-01-31 ATN01, NCT04651400 Phase Not Applicable Recruiting 5 3 Months 300 Mikaela Raymond 2020-12-08
A retrospective study to evaluate the effects of tocilizumab in the treatment of critical COVID-19 pneumonia Coronavirus disease 19 infection, Pneumonia Mechanical ventilation alone, tocilizumab alone, Variable regimens including Standard hospital protocol Stony Brook University Hospital US Phase Not Applicable Status not specified 1 115 2020-12-04
HOO-COVID: Efficacy and Safety of Ozonized Oil (HOO) in COVID-19 Patients Coronavirus disease 19 infection ozonized oil alone, routine standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Istituto Neurologico Mediterraneo NEUROMED Italy 2021-01-31 2021-08-31 DEP_052020, HOO-COVID, NCT04651387 Phase Not Applicable Not yet recruiting 1 7 Months 74 Licia Iacoviello, MD, PhD 2020-12-07
CAGE: COVID-19 And geko Evaluation Coronavirus disease 19 infection geko T3 device alone, peroneal nerve neuromuscular electrical stimulation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Lawson Health Research Institute Canada 2020-12-31 2021-04-30 CAGE, ISS-COV-002, NCT04651374 Phase Not Applicable Not yet recruiting 1 4 Months 40 Jessica Sturt-Smith, Tina Mele, Tina Mele, MD PhD FRCSC 2020-12-07
A retrospective, observational study to evaluate the treatment responses of criteria-based tocilizumab therapy for COVID-19 respiratory infection in ICU and non-ICU patients Coronavirus disease 19 infection, Respiratory tract infection tocilizumab alone Jefferson Health (US) Phase Not Applicable Status not specified 0 170 2020-12-04
A study to evaluate the efficacy of DeepCOVID-XR, the machine-learning algorithm, to detect COVID-19 by analyzing X-ray images of the lungs Coronavirus disease 19 infection DeepCOVID-XR alone Northwestern University US Phase Not Applicable Status not specified 1 2020-12-04
Safety and Immunogenicity of SARS-CoV-2 mRNA Vaccine (BNT-162b2) in Chinese Healthy Population Coronavirus disease 19 infection, Viral pneumonia BNT-162b2 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry BioNTech SE, Jiangsu Province Centers for Disease Control and Prevention Shanghai Fosun Pharmaceutical Industry Development Co Ltd China 2020-12-31 2021-12-31 BNT162-06, ChiCTR2000040044, NCT04649021 Phase 2 Clinical Not yet recruiting 4 12 Months 960 BioNTech Responsible Person, BioNTech clinical trial information desk, Wang Wei, Zhu Fengcai 2020-12-09
Serological Profile of Children and Young Adolescents With at Least One COVID-19 Diagnosed Family Member Coronavirus disease 19 infection Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universita degli Studi di Milano Italy 2020-12-05 2021-12-31 GMT_CD_CT_LG_EB_10_2020, NCT04649944 Phase Not Applicable Not yet recruiting 1 12 Months 40 Giampietro Farronato, DDS, Gianluca Martino Tartaglia, DDS PhD, Gianluca Tartaglia, Professor, Marco Farronato, 2020-12-08
The effect of Steroid on the outpatient treatment of COVID-19 Coronavirus disease 19 infection prednisolone alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Isfahan University of medical Sciences Iran 2020-12-21 IR.MUI.MED.REC.1399.781, IRCT20171219037964N2 Phase 3 Clinical Not yet recruiting 3 70 Babak Amra, Dr. Babak Amra, Dr. Forough Soltaninejad, Dr. Mehrdad Salahi, Shaghayegh Haghjoo 2020-12-08
SAVID: Serum Amyloid A as a prognostic marker for disease severity and mortality in COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Franciscus Gasthuis & Vlietland Siemens Healthcare GmbH Netherlands 2021-01-01 2021-12-31 NL9082, SAVID Phase Not Applicable Planned 1 12 Months 400 Nadine Pouw 2020-12-07
High-Flow Nasal Cannula for severe COVID-19, a multicenter, prospective, cohort study Coronavirus disease 19 infection High-Flow Nasal Cannula alone Franciscus Gasthuis & Vlietland 2020-12-01 2021-12-31 NL9067 Phase Not Applicable Planned 0 13 Months 200 Yasemin Türk 2020-12-04
SHARP-COVID: COVID-19 pandemic impact on severe asthma patients care in Europe Asthma, Coronavirus disease 19 infection Amsterdam University Medical Center Netherlands 2020-11-22 2021-01-31 NL9063, SHARP-COVID Phase Not Applicable Not yet recruiting 1 2 Months 900 Katrien Eger 2020-12-04
Estimation of Dynamics of Humoral and Cellular Immunity in COVID-19 Patients Coronavirus disease 19 infection, Viral pneumonia Humoral and cellular immunity test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus Belarusian State Medical University, Belarussian Research Institute for Epidemiology and Microbiology Belarus 2020-10-01 2021-12-31 IBCE-COVID19-IMMUNITY, NCT04649840 Phase Not Applicable Recruiting 1 15 Months 60 Andrei Hancharou, MD, PHD 2020-12-04
A retrospective study on clinical outcome of tocilizumab in relation to respiratory status improvements and to analyze the association between initial inflammatory markers and treatment outcomes in patients with COVID-19 Coronavirus disease 19 infection tocilizumab alone Saint Barnabas Health Care Systems Phase Not Applicable Status not specified 0 84 2020-12-09
The Impact of COVID-19 on Surgical Practice in Jordan During the Second Outbreak Coronavirus disease 19 infection Yarmouk University Jordan 2020-11-01 2020-11-10 NCT04650035, THE IMPACT OF COVID-19 JORDAN Phase Not Applicable Completed 1 60 Raed M Ennab 2020-12-04
VR Baby, a virtual reality learning environment - does it help medical students to learn about complex topics in obstetrics and gynecology? Coronavirus disease 19 infection Brightspace eLearning University platform alone, VR Baby virtual reality learning environment intervention alone Healthy volunteers accepted University College Dublin Ireland 2020-01-27 2021-03-31 ISRCTN19845486 Phase Not Applicable No longer recruiting 1 14 Months 40 Prof Fionnuala McAuliffe 2020-12-08
AirFLO2 Treatment for Hypoxia and/or Tachypnea in Patients With COVID-19 (AirFLO2) Coronavirus disease 19 infection, Hypoxia, Tachypnea AirFLO2 device alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Duke University Medex Inc US 2020-12-04 2021-06-30 NCT04649775, PRO00105246 Phase Not Applicable Not yet recruiting 1 6 Months 50 Catherine M Foss, BS, Loretta Que, MD, Maria A Santoro, MA 2020-12-04
Early@home Coronavirus disease 19 infection, Viral pneumonia oxygen therapy alone, telemonitoring alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universiteit Utrecht Netherlands 2021-01-11 2021-05-31 NL9081, TBA Phase Not Applicable Not yet recruiting 0 4 Months 100 Harriët van Goor 2020-12-11
Prolonged grief disorder due to the Covid-19 lockdown? - Impact of contact restrictions on the relatives of patients who died during lockdown Anxiety disorder, Coronavirus disease 19 infection, Depression, Psychiatric disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Gießen and Marburg Germany 2020-12-02 178/20, DRKS00023713 Phase Not Applicable Recruiting 0 567 Mr. Dr. med. Christian Volberg 2020-12-11
SOLIDARITY: WHO COVID-19 Solidarity Trial for COVID-19 Treatments Coronavirus disease 19 infection acalabrutinib alone, interferon beta-1a alone, remdesivir alone Btk tyrosine kinase inhibitor, COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The University of The West Indies-Mona Jamaica 2020-12-01 2021-12-31 NCT04647669, SOLIDARITY, SRD/ETH/20 Phase 3 Clinical Not yet recruiting 1 13 Months 100 Marvin E Reid, MB BS PhD, Marvin Reid, Naydenne Williams, MBBS DM, Tomlin Paul 2020-12-04
TeenCove: A Study to Evaluate the Safety, Reactogenicity and Effectiveness of mRNA-1273 Vaccine in Adolescents 12 to < 18 Years Old to Prevent COVID-19 Coronavirus disease 19 infection mRNA-1273 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs) ModeRNA Therapeutics Biomedical Advanced Research and Development Authority (BARDA) US 2020-11-30 2022-06-30 MRNA-1273-P203, NCT04649151, TeenCove Phase 2/Phase 3 Clinical Not yet recruiting 7 19 Months 3000 Moderna Clinical Trials 2020-12-08
Profiling Recovery of Those Discharged Into the Community With COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Derby Sheffield Hallam University, University Hospitals Of Derby and Burton NHS Foundation Trust UK 2021-01-04 2021-12-17 COVID-19-UOD&RDH20/21, NCT04649957 Phase Not Applicable Not yet recruiting 1 11 Months 100 Amanda Baxendale, PhD, Mark A Faghy, PhD, Ruth Ashton, PhD, Tom Bewick, MD, Tom Maden-Wilkinson, PHD 2020-12-07
Well-being in Cancer Patients With Neuropathy During COVID-19 Who Participated in Prior Clinical Trials Coronavirus disease 19 infection, Neuropathic pain MD Anderson Cancer Center National Cancer Institute US 2020-05-26 2021-07-01 2020-0508, 2020-0508, NCI-2020-06014, NCT04650178 Phase Not Applicable Recruiting 1 13 Months 274 Sarah Prinsloo 2020-12-04
Differences in Exhaled Breath by Using Ion Mobility Spectrometry (IMS) in Subjects Tested for SARS-CoV-2 Infection (COVID-19 Disease) Coronavirus disease 19 infection Ion Mobility Spectrometry (IMS) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) B Braun Melsungen AG CeGaT Germany 2020-12-31 2021-05-31 HC-N-H-2006, NCT04649931 Phase Not Applicable Not yet recruiting 1 5 Months 400 Juergen Schaefer, Prof. Dr., Study Manager 2020-12-04
Perception of the COVID-19 Pandemic in Patients With Hematological or Solid Neoplasias Acute stress disorder, Coronavirus disease 19 infection, Hematological neoplasm, Solid tumor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Medizinische Universität Innsbruck Austria 2020-11-23 2020-12-31 1264/2020, NCT04649320 Phase Not Applicable Recruiting 1 1 Month 300 Reinhard Stauder, M.D. 2020-12-04
COVID-19 Nasal Swab Trial Coronavirus disease 19 infection CanSwab alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Orthopaedic Innovation Center Inc Canada 2020-12-31 2021-02-28 B2020:121, NCT04649424 Phase Not Applicable Not yet recruiting 1 2 Months 72 Anand Kumar, MD, Gloria Vasquez-Grande, MD, Kerry Dust, MD, Paul Van Caeseele, MD, Sarah Tran, Trevor Gascoyne 2020-12-04
ResCOVID: A Clinical Trial for Hospitalized Patients With COVID-19 in Ceara Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Escola de Saúde Pública do Ceará Brazil 2020-04-02 2021-12-30 3.948.100, NCT04649827, ResCOVID Phase Not Applicable Recruiting 1 20 Months 3000 Jadson A' Franco, Marcelo A Holanda, PHD 2020-12-04
Convalescent Plasma for Treatment of COVID-19: An Open, Randomized, Controlled Trial Coronavirus disease 19 infection SARS-CoV-2 convalescent plasma alone, steroid therapy alone, SARS-CoV-2 convalescent plasma plus betamethasone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Karolinska University Hospital Danderyd Hospital, Falu Hospital, Karolinska Institutet Sweden 2020-12-03 2022-02-01 CP3, NCT04649879 Phase 2/Phase 3 Clinical Not yet recruiting 3 13 Months 920 Alexandre Bonnard, MD, Anne Börjesson Hanson, Hanna Sahlgren, MD, Joakim Dillner, Joakim Dillner, MD, PhD, Johan Rudling, MD, Johan Ursing, MD, PhD, Karin Norlin, Karl Hagman, MD, Lena Flod, Magnus Hedenstierna, MD, PhD, Maria Eriksdotter, Miia Kivipelto, Ulf Öhlund 2020-12-07
COVID-19 Thrombosis Prevention Trials: Post-hospital Thromboprophylaxis Coronavirus disease 19 infection, Deep vein thrombosis, Ischemic stroke, Lung embolism, Myocardial infarction, Thromboembolism apixaban alone Factor Xa antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Duke University National Heart Lung and Blood Institute US 2020-12-31 2021-09-30 NCT04650087, PRO00107078 Phase 3 Clinical Not yet recruiting 1 9 Months 5320 Thomas L. Ortel, MD, PhD, Thomas Ortel, M.D., Ph.D, Tracy Wang, MD 2020-12-04
Effect of Favipiravir on outpatient treatment of COVID-19 Coronavirus disease 19 infection favipiravir alone RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Isfahan University of medical Sciences Iran 2020-12-21 IR.MUI.MED.REC.1399.780, IRCT20171219037964N3 Phase 3 Clinical Not yet recruiting 3 70 Babak Amra, Dr. Babak Amra, Dr. Forough Soltaninejad, Dr. Mehrdad Salahi, Shaghayegh haghjooy Javanmard 2020-12-04
Variation in Acute Appendicitis During COVID-19 Pandemic in Italy Appendicitis, Coronavirus disease 19 infection appendectomy alone University of Milano-Bicocca Italy 2020-09-01 2020-11-30 APPENDICITE-COVID, Appendicitis-pandemic, NCT04649996 Phase Not Applicable Completed 6 3 Months 532 2020-12-07
A multiple-ascending dose study to evaluate RP-7214 in Covid-19 patients Coronavirus disease 19 infection RP-7214 alone Dihydroorotate dehydrogenase inhibitor Rhizen Pharmaceuticals SA US Phase Not Applicable Planned 1 2020-12-03
ABDALA: ABDALA Clinical Study Coronavirus disease 19 infection CIGB-66 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Center for Genetic Engineering and Biotechnology Cuba 2020-07-12 2021-05-31 ABDALA, IG / CIGB-66I / CVD19 / 2002, RPCEC00000346 Phase 1/Phase 2 Clinical Not yet recruiting 1 10 Months 132 Francisco Hernandez Bernal, Maria Carmen Ricardo Cobas 2020-12-11
Efficacy and Safety of TY-027, a Treatment for COVID-19, in Humans Coronavirus disease 19 infection TY-027, Tychan alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tychan Pte Ltd Singapore 2020-12-04 2021-12-30 NCT04649515, SCT-301 Phase 3 Clinical Not yet recruiting 1 12 Months 1305 Anjali Baglody, MSc, Jenny Low, MBBS, Justin Ng, PhD 2020-12-04
A first-in-man, single ascending dose study to evaluate RP-7214 in healthy subjects Coronavirus disease 19 infection RP-7214 alone Dihydroorotate dehydrogenase inhibitor Healthy volunteers accepted Rhizen Pharmaceuticals SA US Phase 1 Clinical Not yet recruiting 1 2020-12-03
Curmeric-Prevention-COVID-19-Health Personnel-General Calixto Garcia University Hospital Coronavirus disease 19 infection curmeric alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Center for Technological Applications and Nuclear Development (CEADEN) Calixto Garcia Hospital, Ministerio de Salud Publica Cuba 2020-03-19 2020-04-18 RPCEC00000344 Phase Not Applicable No longer recruiting 1 1 Month 199 Tania Valdes González, Yanet Morejon Diaz 2020-12-07
COVID-19 and Sports - an Online Survey on the Impact of the Pandemic and Possible Preventive Measures Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Medizinische Universität Innsbruck Universitat Innsbruck Austria 2020-06-15 2020-08-31 20200609, NCT04649333 Phase Not Applicable Completed 1 2 Months 1336 2020-12-08
STEPCO: Short and Medium-term Effects of Pulmonary Rehabilitation in Mild to Critical Post-acute COVID-19 Coronavirus disease 19 infection pulmonary rehabilitation program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Schön Klinik Berchtesgadener Land Germany 2020-11-25 2021-03-31 COVID-REHAB, NCT04649918, STEPCO Phase Not Applicable Recruiting 1 4 Months 50 Andreas R Koczulla, MD, Rainer Gloeckl, PhD 2020-12-07
Surfactant Protein Genetic Variants in COVID-19 Infection Coronavirus disease 19 infection genetic test alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Milton S. Hershey Medical Center US 2020-03-01 2021-12-31 15456, NCT04650191 Phase Not Applicable Recruiting 1 22 Months 300 Chintan Gandhi, Chintan K Gandhi, MD, MBBS 2020-12-04
A retrospective study to evaluate the epidemiological and clinical characteristics of older patients with COVID-19 outside Wuhan Coronavirus disease 19 infection epidemiological and clinical analysis alone National Natural Science Foundation of China China Phase Not Applicable Status not specified 1 788 2020-12-03
Sharing Stories: a digital intervention for caregivers with young children in the COVID-19 era to promote child social, emotional and language development, responsive parenting and parental mental wellbeing in Zambia, Tanzania and Uganda Coronavirus disease 19 infection, Psychiatric disorder Sharing Stories digital group-based parenting intervention alone University of Stellenbosch The LEGO Foundation Zambia, Uganda, Tanzania 2020-06-01 2021-05-31 ISRCTN77689525 Phase Not Applicable No longer recruiting 4 12 Months 720 Prof Sarah Skeen 2020-12-04
A retrospective study to evaluate the therapeutic effects of adenosine in high flow 21% oxygen aereosol in patients with Covid19-pneumonia Coronavirus disease 19 infection, Pneumonia adenosine alone Universita degli Studi di Roma La Sapienza Phase Not Applicable Status not specified 0 66 2020-12-03
Types of drugs used and their side effects in COVID-19 patients Coronavirus disease 19 infection Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Maulana Azad Medical College India 2020-12-07 CTRI/2020/12/029463 Phase Not Applicable Not yet recruiting 1 1000 Dr Bhupinder Singh, Dr Bhupinder Singh Kalra 2020-12-04
How COVID-19 affected MAHE students diet and lifestyle practices Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs) Welcomgroup Graduate School of Hotel Administration India 2020-12-03 CTRI/2020/12/029456 Phase Not Applicable Not yet recruiting 1 294 Asha Moideen, Aswindev, Aswindev J, Dr Meenakshi Garg 2020-12-04
Study of COVID-19 infection in hemodialysis and post-renal transplant patients Coronavirus disease 19 infection, End stage renal disease, Kidney dialysis, Kidney transplantation Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shree Krishna Hospital, The Healing Tree India 2020-12-11 CTRI/2020/12/029478 Phase Not Applicable Not yet recruiting 1 80 Dr Maulin Shah 2020-12-04
HBOTpCOVID: Hyperbaric Oxygen Therapy for Post-COVID-19 Syndrome Cognitive disorder, Coronavirus disease 19 infection hyperbaric oxygen therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assaf-Harofeh Medical Center Israel 2021-01-01 2023-01-01 332-20-ASF, HBOTpCOVID, NCT04647656 Phase Not Applicable Not yet recruiting 1 24 Months 70 Shai Efrati, Prof., Shani Zilberman-Itskovich, Dr. 2020-12-04
MAMBISA study: Adaptive phase I/II clinical trial, randomized, of parallel-groups, to evaluate the safety and immunogenicity in adults of two vaccine candidates, based on recombinant RBD subunits for the prevention of COVID-19 in regimens that use the nasal route of administration. (COVID-19) Coronavirus disease 19 infection CIGB-66 alone, CIGB-669 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Center for Genetic Engineering and Biotechnology Cuba 2020-12-07 2021-05-31 IG / VPIN / CVD19 / 2001, MAMBISA study, RPCEC00000345 Phase 1/Phase 2 Clinical Not yet recruiting 1 5 Months 88 Carlos Alberto Gonzalez Delgado, Zurina Cinza estevez 2020-12-11
Clinical Characteristics and Outcomes of Patients with COVID-19 Admitted in the ICU of a Tertiary Public Hospital and COVID-19 Referral Center in the Philippines Coronavirus disease 19 infection Philippine General Hospital Philippines 2020-04-01 2020-06-01 PHRR201125-003177 Phase Not Applicable No longer recruiting 1 2 Months Aprille Anne O. Octaviano, Blessie Marie B. Perez, Jubert P. Benedicto, MD 2020-12-03
MAC VITAL: Implementing Peri-operative Mobile Application for Contactless Vital Signs Coronavirus disease 19 infection Anura Research app alone, standard vital sign measurement device alone, vital sign measurement alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The University Health Network Canada 2020-12-15 2024-12-15 MAC VITAL, NCT04648111, PROTOCOL VERSION: OCT 29, 2020 Phase Not Applicable Not yet recruiting 1 48 Months 200 2020-12-02
Effect of medical mask on maternal oxygen saturation and fetal non-stress test during late third trimester of pregnancy in the COVID-19 era Coronavirus disease 19 infection surgical mask alone Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Native American Ancestry Srinakarinwirot University Thailand 2020-12-01 TCTR20201124002 Phase 0 Clinical Not yet recruiting 1 70 Tharangrut Hanprasertpong 2020-12-08
Exploratory Study: COVID-19 and Pregnancy Coronavirus disease 19 infection SARS-CoV-2 serology test alone Healthy volunteers accepted, Female, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo Brazil 2020-09-21 2022-06-13 30270820.3.0000.0068, NCT04647994 Phase Not Applicable Recruiting 1 20 Months 500 Ana CS Farche, PhD, Ana Claudia S Farche, PhD, Rossana P Francisco, PhD 2020-12-03
Re_Co: Medical Rehabilitation after Coronavirus Disease (Covid-19)/ Re_Co Acute stress disorder, Coronavirus disease 19 infection pneumological rehabilitation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Lubeck Deutsche Rentenversicherung Bund Germany 2021-02-01 20-391, DRKS00023642, Re_Co Phase Not Applicable Not yet recruiting 2 580 Ruth Deck 2020-12-03
COVER-Studie: Investigation of factors that may influence the course of a SARS-CoV-2 infection (COVID-19): A study of the University Medical Center Greifswald Coronavirus disease 19 infection questionnaire alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Medicine Greifswald Germany 2020-04-30 BB 059/20, COVER-Studie, DRKS00021672 Phase Not Applicable Recruiting 1 400 Eik Schäfer, Klaus Hahnenkamp, Wolfgang Hoffmann 2020-12-03
A cohort study to evaluate the clinical and laboratory features and short-term outcomes of patients with coronavirus disease 2019 (COVID-19) Coronavirus disease 19 infection antimicrobial alone, clinical and laboratory features analysis alone, glucocorticoid alone Chinese Academy of Medical Sciences China Phase Not Applicable Status not specified 1 102 2020-12-02
IFN-beta-1b and Remdesivir for COVID19 Coronavirus disease 19 infection interferon beta-1b plus remdesivir COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The University of Hong Kong Hong Kong 2020-11-20 2021-09-30 NCT04647695, UW 20-535 Phase 2 Clinical Recruiting 1 10 Months 100 Ivan FN Hung, MD FRCP, Kelvin KW To, MD FRCPath 2020-12-04
ASAP-C: Corticosteroids in Severe COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Brno Czech Republic 2021-01-01 2021-04-01 ASAP-C, ASAP-C STUDY, NCT04648410 Phase Not Applicable Not yet recruiting 1 3 Months 2000 Jan Malaska, MD. Ph.D., Jan Malaska, MD., Ph.D, Jozef Klučka, assoc.Prof.MD, Ph.D, Jozef Klučka, assoc.prof.MD.Ph.D., Petr Štourač 2020-12-03
A retrospective study to evaluate the negative impact of hyperglycaemia on tocilizumab therapy in Covid-19 patients Coronavirus disease 19 infection, Hyperglycemia tocilizumab alone University of Campania Luigi Vanvitelli Italy Phase Not Applicable Status not specified 1 475 2020-12-02
Starling Registry Study Coronavirus disease 19 infection Starling detector system alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Baxter Healthcare Corp US 2020-12-07 2022-07-31 BXU553561, NCT04648293 Phase Not Applicable Not yet recruiting 1 19 Months 600 Baxter Clinical Trials Disclosure Call Center, Jennifer Sahatjian 2020-12-02
Covid outcomes among patients with comorbidities Asthma, Cancer, Cardiovascular disease, Cerebrovascular trauma, Chronic obstructive pulmonary disease, Connective tissue disease, Coronavirus disease 19 infection, Diabetes mellitus, Endocrine disease, HIV infection, Hematological disease, Hypertension, Immune deficiency, Interstitial lung disease, Mycobacterium tuberculosis infection, Obesity, Psychiatric disorder, Renal disease, Rheumatoid arthritis, Systemic lupus erythematosus, Vasculitis Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sri Ramachandra University India 2020-12-15 CTRI/2020/12/029452 Phase Not Applicable Not yet recruiting 1 1000 Dr Swathy Moorthy, DrSPThiagarajan 2020-12-03
A phase IV clinical study to assess Carragelose in healthcare professionals, who are managing COVID-19 patients Coronavirus disease 19 infection iorta-carrageenan (intranasal, COVID-19), Marinomed Biotechnology alone Marinomed Biotechnologie GmbH Austria Phase 4 Clinical Planned 1 334 Dr. Christoph Wenisch 2020-12-02
CLARITY: Controlled evaLuation of Angiotensin Receptor Blockers (DMX-200) for COVID-19 respiratory disease Coronavirus disease 19 infection irbesartan + propagermanium (oral extended release, chronic kidney disease/diabetic retinopathy/NASH/focal segmental glomerulosclerosis/diabetic nephropathy), Dimerix Bioscience alone Angiotensin II AT-1 receptor antagonist, CCR2 chemokine antagonist Dimerix Bioscience Pty Ltd CLARITY Phase Not Applicable Status not specified 0 2020-12-08
CLARITY 2.0: A prospective, multicenter, randomized, double-blind, placebo-controlled study to evaluate the assess the safety and effectiveness of DMX-200 in COVID-19 patients Coronavirus disease 19 infection irbesartan + propagermanium (oral extended release, chronic kidney disease/diabetic retinopathy/NASH/focal segmental glomerulosclerosis/diabetic nephropathy), Dimerix Bioscience alone Angiotensin II AT-1 receptor antagonist, CCR2 chemokine antagonist Dimerix Bioscience Pty Ltd Australia CLARITY 2.0 Phase 3 Clinical Recruiting 1 600 Meg Jardine 2020-12-08
A clinical study to determine the effect of CL-20189 and CL-20193 in mild to moderate COVID-19 patients Coronavirus disease 19 infection CL-20189 alone, CL-20193 alone, standard therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) CLS Pvt Ltd India 2020-12-07 CLS/CV/CL20189/20 Version 1.0, CTRI/2020/12/029475 Phase 2 Clinical Not yet recruiting 1 66 Dr K Sunil Naik, Mr Ajjarapu Srinivasu, Mr Kavangula Krishna Chaitanya 2020-12-03
A clinical trial to study the effect of herbal medicine on enhancing immune function in COVID recovery patients Coronavirus disease 19 infection aswagandha + amla + shilajeet extract alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Natreon Inc, Kolkata India 2020-12-15 CTRI/2020/12/029476, JBR/RU/CT-16/20 version 1.3 Phase 2 Clinical Not yet recruiting 1 120 Dr Srikanta Pandit 2020-12-04
COVIMMUNITY: Evaluation and Longitudinal Follow-up of Biomarkers Predictive of Severe Forms of COVID-19 Coronavirus disease 19 infection ELISPOT assay alone, QuantiFERON assay alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire de Saint Etienne France 2020-12-01 2022-12-01 20CH207, COVIMMUNITY, NCT04648709 Phase Not Applicable Not yet recruiting 1 24 Months 100 Anne-Emmanuelle BERGER, MD, Florence Rancon, Stéphane PAUL, Stéphane Paul, PHD 2020-12-04
COVPROSHIELD: Effectiveness and Adherence to Closed Face Shields to Prevent COVID-19 Transmission Coronavirus disease 19 infection Closed face shield alone, Surgical face mask alone, educational video alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidad Los Andes Roche Pharma AG, United Nations Colombia 2020-12-31 2021-03-31 1010166518, COVPROSHIELD, NCT04647305 Phase Not Applicable Not yet recruiting 1 3 Months 233 Alejandro Pacheco Gurruchaga, MSc, Andrea Ramirez Varela, PhD, Eduardo Behrentz, PhD, Giancarlo Buitrago Gutierrez, PhD, Jhon M. Gonzalez, PhD, José D. Pinzón, MSc, Juan D. Martin, MSc, Juan J. Yepes Nuñez, PhD, Luis J. Hernandez Florez, PhD, Rachid Laajaj, PhD, Silvia Restrepo Restrepo, PhD 2020-12-02
CRISOL Contigo: Multi-level Intervention to Reduce the Disproportionate Toll of COVID-19 Among Latino Communities in Philadelphia Coronavirus disease 19 infection, Psychiatric disorder Community popular opinion leader (POL) based intervention alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Drexel University US 2021-01-06 2021-10-31 3R21MD012352-02S1, CRISOL Contigo, NCT04646616 Phase Not Applicable Not yet recruiting 0 9 Months 800 Amy Carroll-Scott, PhD, Ana Martinez Donate, Ana Martinez-Donate, PhD, Mariana Lazo, PhD, Seth L. Welles, PhD 2020-12-09
NOS: Nutritional Status in Locally Advanced or Metastatic Solid Cancer Patients in Spain: the NutriOncoSearch (NOS) Study Advanced solid tumor, Coronavirus disease 19 infection, Malnutrition chemotherapy alone, immunotherapy alone, radiotherapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidad Pontificia Comillas De Madrid Baxter Healthcare Corp, European Society for Medical Oncology, IQVIA RDS Pty Ltd Spain 2020-06-10 2020-12-15 NCT04168814, NOS, SEEO-19-01-NOS Phase Not Applicable No longer recruiting 11 6 Months 586 Julio C de la Torre-Montero, Ph.D 2020-12-03
Responsible Gambling Telephone Intervention to High-risk Gamblers by a State-owned Gambling Operator in Sweden Coronavirus disease 19 infection Motivational telephone intervention alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Lunds University Bioscience Svenska Spel Sweden 2020-11-30 2021-11-30 NCT04646421, OMSORGSSAMTAL Phase Not Applicable Recruiting 1 12 Months 3626 Anders Håkansson, PhD 2020-12-03
The effect of hemoperfusion on patients with severe symptoms of covid-19 which are resistant to conventional therapies Coronavirus disease 19 infection, Respiratory distress syndrome hemoperfusion alone Oroumia University of Medical Sciences Iran 2020-11-10 IR.UMSU.REC.1399.259, IRCT20180625040232N7 Phase Not Applicable Recruiting 1 20 Saman Farshid, ِDr Iraj Mohebi 2020-12-02
Effects of herbal drug Imfluna on patients with COVID-19 Coronavirus disease 19 infection, Viral pneumonia Imfluna, Zarsan Salamat Pharmaceutical Company alone, standard medications alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Zarsan Salamat Company Iran 2020-11-15 IR.MEDSAB.REC.1399.115, IRCT20080901001157N17 Phase 2 Clinical Recruiting 1 60 Afsaneh Kafash, Fallah Huseini Hasan, Fereshtah Qorat, Mehdi Khairabadi, Mohammadreza Gholibeikian 2020-12-02
Epidemiology and clinical features in patients with COVID-19 in Mexican Southeast: A retrospective analysis Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Regional de Alta Especialidad Juan Graham Tabasco Mexico 2020-03-30 2020-12-31 ACTRN12620001265965, ANZCTR380303 Phase Not Applicable No longer recruiting 1 9 Months 1000 Guadalupe del Carmen Baeza Flores, Jesús Arturo Ruiz Quinones 2020-12-02
Evaluation of SARS-CoV-2 Serum Antibody Titer in Pediatric Health Workers Coronavirus disease 19 infection St Marianna University School of Medicine Japan 2020-12-01 UMIN000042599 Phase Not Applicable Not yet recruiting 1 30 Yukitsugu Nakamura 2020-12-02
A phase IV study of iorta-carrageenan (intranasal, COVID-19), Marinomed Biotechnology for the prevention of SARS-CoV-2 infection Coronavirus disease 19 infection iorta-carrageenan (intranasal, COVID-19), Marinomed Biotechnology alone Marinomed Biotechnologie GmbH Phase 4 Clinical Planned 0 2020-12-02
A Phase III Clinical Trial to Determine the Safety and Efficacy of ZF-2001 for Prevention of COVID-19 Coronavirus disease 19 infection ZF-2001 (Anhui Zhifei Longcom Biopharmaceutical Co Ltd) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry Anhui Zhifei Longcom Biopharmaceutical Co Ltd China 2020-12-31 2022-04-30 LKM-2020-NCV-GJ01, NCT04646590 Phase 3 Clinical Not yet recruiting 1 16 Months 29000 Fan Di, Master, Fangjun Li, Bachelor 2020-12-02
MRG-001 as an Immunoregulatory and Regenerative Therapy for COVID-19 Patients Coronavirus disease 19 infection MRG-001, Medregen alone Young Adults (18-44 yrs) Medregen Llc Kendall Healthcare Group, Ltd US 2021-01-05 2021-06-05 MRG2020, NCT04646603 Phase 1/Phase 2 Clinical Not yet recruiting 1 5 Months 12 Ali R Ahmadi, PhD, James F Burdick, MD, Michael E Nottidge, MD 2020-12-08
Psychological Health, Coping Strategies and Preferences of Military COVID-19 Deployers Acute stress disorder, Coronavirus disease 19 infection Healthy volunteers accepted David Grant USAF Medical Center US 2020-12-31 2021-05-31 FWH20200203E, NCT04646642 Phase Not Applicable Not yet recruiting 1 5 Months 160 Amanda Fox 2020-12-02
The Relationship Between Covid-19 Infection in Pediatric Patients and Secondary Lymphoid Organs Coronavirus disease 19 infection Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) Selcuk University Turkey 2020-10-01 2021-02-01 2020/480, NCT04646525 Phase Not Applicable Recruiting 1 4 Months 300 Merih Onal, Assist. Prof., Merih Onal, M.D., Selcen Celik 2020-12-02
ARC: Establish and analyse a model of care for the management of people taking oral anti-cancer medications by an Advanced Nurse Practitioner: a pilot study Cancer, Coronavirus disease 19 infection anti-cancer medication alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Irish Cancer Society Ireland 2020-04-08 2022-09-14 ARC, CNRA19RICH, ISRCTN10401455 Phase Not Applicable Recruiting 2 29 Months 40 Dr Janice Richmond, Prof Andrew Murphy 2020-12-02
EMOS-COVID: Enoxaparin at Prophylactic or Therapeutic Doses in COVID-19 Coronavirus disease 19 infection, Respiratory failure, Thrombosis, Viral pneumonia enoxaparin sodium alone Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) ASST Fatebenefratelli Sacco Universita degli Studi di Milano, Universita' Degli Studi Di Foggia, University of Milano-Bicocca Italy 2020-07-27 2021-07-31 EMOS-COVID, HLS-02COVID19/2020, NCT04646655 Phase 3 Clinical Recruiting 1 12 Months 300 Maddalena A Wu, M.D., Massimo Arquati, M.D. 2020-12-02
Effect of internet-delivered psychoeducation program named 'Imacoco-care' on improving psychological distress among workers under COVID-19 infection Acute stress disorder, Coronavirus disease 19 infection, Panic disorder Imacoco-care alone, internet-delivered psychoeducational program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Tokyo Japan 2020-12-05 UMIN000042556 Phase Not Applicable Not yet recruiting 1 1000 Kotaro Imamura, Norito Kawakami 2020-12-02
Covid-19 Risk Factors and Pattern Between Healthcare Workers Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assiut University Egypt 2020-12-31 2022-01-31 COVID-19 PATTERRN, NCT04646551 Phase Not Applicable Not yet recruiting 1 13 Months 165 Duaa Bahgat Abdelhamed, Mohamed Mostafa Abdelhady, Sahar Ahmed, Sahar Ahmed Okily 2020-12-02
Remote Patient Monitoring (RPM) for patients with COVID-19 and other infection Coronavirus disease 19 infection, Infectious disease Medopad alone, Remote patient monitoring solutions alone, SaniQ Infekt alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Zentralinstitut für die kassenärztliche Versorgung in der Bundesrepublik Deutschland Germany 2020-12-01 DRKS00023553, Eth-KB 19/20 Phase Not Applicable Not yet recruiting 6 120 Sarah Eichler 2020-12-03
STOP CC: Effects of a low-threshold Substitution Therape of Opioid-dependent Patients during the Corona Crisis (COVID-19) Coronavirus disease 19 infection, Opiate dependence substitution therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Drob Inn University of Hamburg Germany 2020-10-14 2020-10058-BO, DRKS00023401, STOP CC Phase Not Applicable Recruiting 1 80 Fabian Vorberg, Uwe Verthein 2020-12-03
CoV-Surv: Effectiveness and cost-effectiveness of four different strategies for SARS-CoV-2 surveillance in the general population: study protocol for a cluster-randomized, two-factorial, controlled trial Coronavirus disease 19 infection Reverse Transcription Loop-mediated Isothermal Amplification (RT-LAMP) alone, pre-screening questionnaire alone, saliva sample alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Heidelberg Bundesministerium für Bildung und Forschung, Gesundheitsamt Rhein-Neckar Germany 2020-11-18 CoV-Surv, DRKS00023271, S-790/2020, U1111-1259-3834 Phase Not Applicable Recruiting 1 10000 Andreas Deckert 2020-12-02
CarECorona: Nursing care in times of corona (Covid-19). Scientific study on challenges and pressures from the perspective of leaders (continued) Is the threat of system collapse still present or are we normalizing the madness? Coronavirus disease 19 infection Lime-Survey alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Cologne Germany 2020-12-03 20-1459, CarECorona, DRKS00023402 Phase Not Applicable Recruiting 1 1000 Kira Hower 2020-12-02
A clinical trial to study effect of Madhav Rasayan tablets in COVID-19 patients Coronavirus disease 19 infection Madhav Rasayan alone, Standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Shri Vishwavati Ayurved Chikitsalaya and Research Centre India 2020-12-03 CTRI/2020/11/029444, SVACRC/20/1 V 2.0 Phase 3 Clinical Not yet recruiting 0 60 Dr Pankaj H Bansode, Dr Tushar Saundankar, Shailesh Balkrishna Malekar 2020-12-10
Effect of remote management on comprehensive management of diabetes mellitus during the COVID-19 epidemic Coronavirus disease 19 infection, Diabetes mellitus WeChat APP alone, remote management alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Second Hospital of Jilin University China 2020-12-01 2021-05-01 ChiCTR2000040366 Phase Not Applicable Recruiting 1 5 Months 90 Chuan Zhang, Jing Kang 2020-12-02
Special project to support elderly singleton or doubleton in the new wave of COVID-19 pandemic Coronavirus disease 19 infection Telecare alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) China 2020-12-01 2022-11-30 ChiCTR2000040324 Phase 0 Clinical Recruiting 1 24 Months 11000 Daisy Dexing Zhang, Samuel YS Wong 2020-12-04
Reinfection with SARS-COV-2 and associated factors Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Christian Medical College, Vellore, India Bill & Melinda Gates Foundation India 2021-01-04 CTRI/2020/11/029438 Phase Not Applicable Not yet recruiting 0 600 Jacob John 2020-12-10
A phase I clinical trial to evaluate the safety and immunogenicity of BNT-162b2 in healthy Chinese subjects Coronavirus disease 19 infection BNT-162b2 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Asian Ancestry BioNTech SE, Shanghai Fosun Pharmaceutical (Group) Co Ltd China 2020-08-01 Phase 1 Clinical Recruiting 1 2020-12-01
Effect of Favipiravir on Mortality in Patients With COVID-19 at a Tertiary Center Intensive Care Unit Coronavirus disease 19 infection favipiravir alone, lopinavir + ritonavir alone HIV protease inhibitor, RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sisli Hamidiye Etfal Training and Research Hospital Turkey 2020-03-15 2020-05-15 2854, NCT04645433 Phase Not Applicable Completed 1 2 Months 100 sultan acar sevinc 2020-12-02
A phase I/II, randomized, double-blind, placebo-controlled, two-stage, multicenter study of HFB-30132A in the treatment of patients with COVID-19 infection Coronavirus disease 19 infection HFB-30132A alone Angiotensin converting enzyme 2 inhibitor, COVID19 Spike glycoprotein inhibitor HiFiBio PJSC Pharmsynthez, Shemyakin Institute of Bioorganic Chemistry Russian Federation Phase 1/Phase 2 Clinical Planned 1 2020-11-30
The effect of wearing face masks on cognitive functioning Cognitive disorder, Coronavirus disease 19 infection PPE mask (Safe Plus) alone Healthy volunteers accepted, Young Adults (18-44 yrs) University of Otago New Zealand 2020-07-29 2020-10-27 ACTRN12620001215910, ANZCTR380747 Phase Not Applicable Completed 1 2 Months 50 Liana Machado, Neda Nasrollahi 2020-12-02
Investigating the safety, satisfaction and efficacy of pulmonary tele rehabilitation for people with respiratory conditions, including patients recovering from COVID-19 Asthma, Bronchiectasis, Chronic obstructive pulmonary disease, Coronavirus disease 19 infection, Interstitial lung disease, Lung tumor Aerobic training alone, Strength training alone, Warm up stretches alone, education sessions alone, pulmonary telerehab exercise training alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Royal Prince Alfred Hospital Australia 2021-02-01 ACTRN12620001279910p, ANZCTR380787, U1111-1259-9240 Phase Not Applicable Not yet recruiting 1 100 Lissa Spencer 2020-12-01
Effects of Fuzheng Huayu Tablets on COVID-19 Coronavirus disease 19 infection Fuzheng Huayu capsule alone, conventional therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) ShuGuang Hospital, China Hubei province hospital of Traditional Chinese Medicine, Jingmen No.1 People’s Hospital China 2020-02-01 2020-04-15 FZHY-NCP-1, NCT04645407 Phase 4 Clinical Completed 1 2 Months 66 Liu Chenghai 2020-12-02
Using Whatsapp for the Consultation Coronavirus disease 19 infection Infectious disease specialist-led video consultation alone, whastapp application alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kafkas University Turkey 2020-03-11 2020-05-31 CLINICAL-3, NCT04645563 Phase Not Applicable Completed 1 2 Months 144 Ramazan Sbirli 2020-12-02
A novel PhIV precision medicine interventional clinical trial to assess potential link between COVID-19 and hypertension Coronavirus disease 19 infection, Hypertension drug therapy alone, smart phone app alone Closed Loop Medicine Ltd Queen Mary University of London, Technology Strategy Board, William Harvey Clinical Research Centre 2020-11-18 Phase Not Applicable Recruiting 0 1000 2020-11-30
Impact of COVID-19 pandemic on hepatobiliary and pancreatic surgical services Coronavirus disease 19 infection, Surgical procedure Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tan Tock Seng Hospital Singapore 2019-01-01 2020-06-30 ChiCTR2000040265 Phase Not Applicable Completed 1 18 Months 547 Teo Zhe Hao Timothy 2020-12-02
A study to evaluate post COVID-19 lung damage Coronavirus disease 19 infection, Lung injury, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Medanta The Medicity India 2020-12-15 COVIP/2020/001 Version 01, CTRI/2020/11/029437 Phase Not Applicable Not yet recruiting 1 300 Dr Bornali Datta 2020-12-03
A Placebo-Controlled Trial of Bempegaldesleukin (BEMPEG; NKTR-214) With Standard of Care in Patients With Mild COVID-19 Coronavirus disease 19 infection bempegaldesleukin alone, standard of care alone CD122 agonist, IL-2 receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Nektar Therapeutics US 2020-11-13 2021-03-27 20-214-34, NCT04646044 Phase 1b Clinical Recruiting 2 4 Months 30 Nektar, Praveena Raman, Study Director 2020-12-01
Covid with AKI Coronavirus disease 19 infection, Renal injury Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sardar Vallabhbhai Patel Institute of Medical Science and Research India 2020-12-14 CTRI/2020/11/029414 Phase Not Applicable Not yet recruiting 1 100 DR ISHAN A DESAI, DR NEHAL M SHAH 2020-12-01
PEPCO: A Phase III, post exposure prophylaxis for COVID-19 study to evaluate avigan tablets (favipiravir) in the prevention of COVID-19 Coronavirus disease 19 infection Avigan alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Appili Therapeutics Inc Cato Research LLC Canada, US PEPCO Phase 3 Clinical Not yet recruiting 2 1156 2020-12-04
An observational study to evaluate the effect of hydroxychloroquine and azithromycin on arrhythmic profile and QT interval in patients with COVID-19 Coronavirus disease 19 infection azithromycin plus hydroxychloroquine Healthy volunteers accepted University of Padova Phase Not Applicable Status not specified 0 22 2020-11-30
Efficacy of Date Palm Leaf Extract (Phoenix dactylifera) in Patients with COVID-19 Hospitalized in Ganjavian Hospital in Dezful Coronavirus disease 19 infection palm leaf extract (Phoenix dactylifera) alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dezful University of Medical Sciences Iran 2020-09-12 2020-11-16 IR.DUMS.REC.1399.037, IRCT20201015049036N1 Phase 2 Clinical Completed 1 2 Months 100 Dr. Maysam Mard Soltani, Mohammad Dorchin 2020-12-01
Expanded-Access to T-89 for Treatment Use in Intermediate-size Patients Population With COVID-19 Coronavirus disease 19 infection T-89 alone Tasly Pharmaceuticals Inc Tasly Pharmaceutical Group Co Ltd US NCT04646031, T89-ROUSA-01 Phase Not Applicable Recruiting 1 Anni Li, Danielle Wahinekapu, Henry H Sun, PhD, MD, Libby Bliss, Patrick Meehan, PhD, MD 2020-12-01
Biomarkers of Trained Immunity Following MMR Vaccination Coronavirus disease 19 infection MMR vaccine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Washington University School of Medicine, US 2020-12-31 2021-04-30 202011081, NCT04646239 Phase Not Applicable Not yet recruiting 1 4 Months 80 Jonathan Jocum, MD, Leon du Toit, MD, Linda Yun, Michael S Avidan, MD, Shabaana Khader, PhD, Shail Mehta, MD 2020-12-06
Ivermectin for Severe COVID-19 Management Coronavirus disease 19 infection, Viral pneumonia Variable regimens including azithromycin , favipiravir , hydroxychloroquine , ivermectin (solution/enteral, COVID-19), NeuTec Pharma/Afyonkarahisar Health Sciences University RNA polymerase inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Afyon karahisar University of Health Sciences NeuTec Pharma plc Turkey 2020-05-11 2020-09-02 IVMC_03, NCT04646109 Phase 3 Clinical Completed 4 3 Months 60 Neşe Demirtürk, A. Prof. Dr., Nurullah Okumuş, Nurullah Okumuş, Prof. Dr., Rahmet Güner, Prof. Dr., Rıza A. Çetinkaya, Prof. Dr., İsmail Y. Avcı 2020-12-09
COVID19-MHM: COVID-19 and Hereditary Metabolic Diseases Coronavirus disease 19 infection, Gaucher disease, Urea cycle disorder Centre Hospitalier Regional Universitaire de Lille France 2021-01-31 2023-01-31 2020-A02886-33, 2020_52, COVID19-MHM, NCT04645498 Phase Not Applicable Not yet recruiting 1 24 Months 77 Claire Douillard, MD 2020-12-01
Comparing two medications (dexamethasone and methylprednisolone high dose) for the treatment of pneumonia in patients with COVID-19 Coronavirus disease 19 infection, Viral pneumonia Dexamethasone alone, methylprednisolone alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Clínica Medellín - Comprometidos con tu Salud Colombia 2020-04-01 2020-11-15 20-33686, ISRCTN33037282 Phase Not Applicable Completed 1 7 Months 213 Dr Pinzón 2020-12-03
Study of Longidaze in the Prevention and Treatment of Pulmonary Fibrosis, Interstitial Lung Diseases Caused by COVID-19 Coronavirus disease 19 infection, Interstitial lung disease, Pulmonary fibrosis Botkin.AI alone, bovhyaluronidase azoximer alone Hyaluronidase stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) NPO Petrovax Pharm LLC Kazakhstan, Russian Federation 2020-07-01 2021-07-31 DISSOLVE, NCT04645368 Phase Not Applicable Recruiting 16 13 Months 160 A. A. Zaycev, A. G. Borisov, A. U. Petuhova, G. L. Ignatova, L. I. Korneva, L. M. Kudelya, N. V. Kotova, Nikolay S. Dodonov, O. A. Chernyavskaya, O. A. Shagabutdinova, O. V. Masalkina, T. R. Kasyanova, T. V. Rubanik, U. V. Argamakova, V. V. Naumov 2020-12-01
SSC: SARS-CoV-2 Surveillance in childcare facilities Coronavirus disease 19 infection SARS-CoV-2 surveillance alone, saliva samples alone Uniklinik Köln - Zentrum Innere Medizin Germany 2020-11-29 20-1466, DRKS00023507, SSC Phase Not Applicable Recruiting 1 120 Felix Dewald 2020-12-01
A multicenter, single-blind, randomized controlled trial on ruxolitinb in treatment of severe coronavirus disease 2019 Coronavirus disease 19 infection ruxolitinib alone, standard-of-care alone Jak1 tyrosine kinase inhibitor, Jak2 tyrosine kinase inhibitor Cincinnati Children's Hospital Medical Center, Huazhong University of Science and Technology Phase 2 Clinical Status not specified 0 43 2020-12-08
Self-perceived depression, anxiety, stress in caregivers of patients in IKN during COVID-19 pandemic Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression Universiti Sains Malaysia Malaysia 2021-01-17 2021-10-17 57267, NMRR-20-2534-57267 Phase Not Applicable Status not specified 2 9 Months Sarah Aqilah Binti Ghazali 2020-11-30
The outcome of Pohon Sihat among healthcare workers during COVID-19 Coronavirus disease 19 infection Hospital Kuala Lumpur Malaysia 2021-01-01 2021-04-30 55907, NMRR-20-2568-55907 Phase Not Applicable Recruiting 1 4 Months 60 Hariani binti ishak 2020-11-30
DOSHHCW: COVID-19 Pandemic: determinants of occupational safety and health compliance among healthcare workers in Penampang and Putatan districts of Sabah Coronavirus disease 19 infection PEJABAT KESIHATAN KAWASAN PENAMPANG Malaysia 2020-12-01 2021-12-01 57340, DOSHHCW, NMRR-20-2554-57340 Phase Not Applicable Not yet recruiting 1 12 Months Dr Ahmad Firdaus bin Mohamed, Dr SAM FROZE ANAK JIEE 2020-12-06
New norms and PPE usage compliancy Coronavirus disease 19 infection Slim River Hospital Malaysia 2020-11-27 2021-01-26 57427, NMRR-20-2547-57427 Phase Not Applicable Status not specified 1 2 Months Dr Nur Hidayah Binti P.Azhar 2020-11-30
An observational, retrospective study to compare the outcome of metformin users and nonusers in hospitalized COVID-19 patients with diabetes Coronavirus disease 19 infection, Diabetes mellitus metformin hydrochloride alone AMP activated protein kinase stimulator Tongji Hospital, Huazhong University of Science and Technology China Phase Not Applicable Status not specified 1 283 2020-11-30
A Phase II, Randomized, Double-blinded, Placebo-controlled, Dose-finding Clinical Study to Evaluate the Safety and Immunogenicity of Different Doses of INO-4800 Administered Intradermally Followed by Electroporation in Healthy Adult and Elderly Volunteers Coronavirus disease 19 infection INO-4800 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Advaccine (Suzhou) Biopharmaceuticals Co Ltd, Jiangsu Province Centers for Disease Control and Prevention China 2020-11-27 2020-12-15 ChiCTR2000040146 Phase 2 Clinical Not yet recruiting 1 640 Fengcai Zhu, Xuefen Huai 2020-12-01
Eye Diseases associated with COVID-19 Choroid disease, Coronavirus disease 19 infection, Retinopathy bedside fundus examination alone, ophthalmoscopy alone, optical coherence tomography alone, optical coherence tomography angiography alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Lilavati Hospital and Research Center India 2020-11-30 CTRI/2020/11/029393 Phase Not Applicable Not yet recruiting 1 30 Dr Salil Mehta 2020-12-02
A study of clinical profile of children with COVID-19 Infection admitted at tertiary care hospital Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs) Smt. NHL Municipal Medical College India 2020-11-28 CTRI/2020/11/029390 Phase Not Applicable Not yet recruiting 1 200 DR Sweety Patel 2020-11-30
Virtual Enhanced Lifestyle for Metabolic Syndrome (ELM) Proof-of-Concept Study Coronavirus disease 19 infection, Metabolic syndrome X virtual enhanced lifestyle for metabolic syndrome program alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rush University Medical Center Geisinger Clinic, Rochester Institute Of Technology, University of Colorado, University of Missouri US 2020-08-01 2021-03-30 20061108, NCT04637477 Phase Not Applicable No longer recruiting 2 7 Months 10 Lynda Powell, PhD 2020-12-01
Phase II, Multi-Site, Randomized, Placebo-Controlled, Double-Blind, Single-Dose Study of TY-027 for Early Treatment of COVID-19 Coronavirus disease 19 infection TY-027, Tychan alone Tychan Pte Ltd Singapore SCT-201 Phase 2 Clinical Status not specified 1 Dr Jenny Low 2020-11-30
XACT: Factor Xa Inhibitor Versus Standard of Care Heparin in Hospitalized Patients With COVID-19 Coronavirus disease 19 infection rivaroxaban alone Factor Xa antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) St. David's HealthCare US 2020-12-01 2021-07-31 2020-001708-41, NCT04640181, XACT Phase 2 Clinical Not yet recruiting 1 8 Months 150 Edward Chafizadeh, MD, Matt Cowperthwaite, PhD, Theresa Pham, MD 2020-12-10
Pirdal Nasal Spray in preventing symptomatic manifestation of disease in COVID-19 proven cases Coronavirus disease 19 infection, Respiratory distress syndrome Covispray (Vitro-Bio Sarl) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Mudra Clincare, Vitro-Bio Sarl India 2020-11-27 CTRI/2020/11/029388, PIR/OBS/2020, Version No.: 4.0 Phase 2 Clinical Not yet recruiting 1 200 Dr S Sadgune, Dr Uma Mulay 2020-12-02
Evaluation of the efficacy and safety of bromhexine administration in COVID-19 Coronavirus disease 19 infection Variable regimens including bromhexine (Tolid Daru Company) , interferon beta-1a follow-on biologic (subcutaneous), CinnaGen , lopinavir + ritonavir (Hetero Labs Limited) Interferon beta ligand Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shaheed Beheshti Medical University Iran 2020-07-10 IR.SBMU.NRITLD.REC.1399.142, IRCT20151227025726N24 Phase 2 Clinical No longer recruiting 1 100 Afshin Zarghi, Farzaneh Dastan, Payam Tabarsi 2020-11-30
A phase II clinical study to assess Persavita's experimental natural health product in the treatment of patients with COVID-19 Coronavirus disease 19 infection natural health product alone Persavita Ltd Canada Phase Not Applicable Planned 1 Dr Piraee 2020-11-27
Effect of cupping on respiratory symptoms of COVID-19 Coronavirus disease 19 infection, Respiratory disease cupping therapy alone, disposable plastic cup alone, standard medication therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Shaheed Beheshti Medical University Iran 2020-09-08 IR.SBMU.RETECH.REC.1399.563, IRCT20200428047229N3 Phase 3 Clinical No longer recruiting 1 72 Dr. Rasool Choopani, Hanieh Tahermohammadi, Zahra Aqanouri 2020-12-10
Formative research for management of serious infections in infants < 2 months of age during COVID pandemic Bacterial infection, Coronavirus disease 19 infection Healthy volunteers accepted Society for Applied Studies World Health Organization India 2020-12-15 CTRI/2020/11/029377 Phase Not Applicable Not yet recruiting 1 70 Nita Bhandari, Sarmila Mazumder 2020-11-30
An online study to assess the disposal of Personal protective equipments at home amid COVID-19 Pandemic in India Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Lady Hardinge Medical College India 2020-05-06 CTRI/2020/11/029376 Phase Not Applicable Completed 1 500 ARCHANA THAKUR 2020-11-30
Pentoxifyliine in COVID-19 Coronavirus disease 19 infection, Viral pneumonia Variable regimens including hydroxychloroquine , interferon beta-1b , lopinavir + ritonavir , pentoxyfylline, Arya company HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mazandaran University of Medical Sciences Iran 2020-11-10 IR.MAZUMS.REC.1399.744, IRCT20190804044429N4 Phase 2/Phase 3 Clinical Recruiting 1 60 Majid Saeedi, Monireh Ghazaeian 2020-12-02
A clinical study to compare high-flow nasal oxygen and non-invasive ventilation in patients with COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure high-flow nasal cannula therapy alone, non-invasive ventilation alone, oxygen alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) BLDE University Sri B. M. Patil Medical College India 2020-11-25 CTRI/2020/11/029356 Phase 2 Clinical Not yet recruiting 1 82 Dr Pratibha S D 2020-11-30
Assessing the knowledge and precautions taken by dentists and dental auxiliaries (operating, non-operating) in dental office during the pandemic of Corona virus (COVID-19) Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Manipal College of Dental Sciences India 2020-12-01 CTRI/2020/11/029350 Phase 2/Phase 3 Clinical Not yet recruiting 1 108 Dr Deepak Kumar Singhal, Dr Saloni Gupta 2020-11-30
Spectrum of eye infections in COVID-19 affected individuals Coronavirus disease 19 infection, Endophthalmitis, Panophthalmitis, Uveitis abscess drainage treatment alone, cycloplegic treatment alone, empirical intra-vitreal antibiotic therapy alone, exudation clearance treatment alone, intraocular antibiotic injection therapy alone, non steroidal anti inflammatory drug therapy alone, pars plana vitrectomy alone, silicone oil based retina attachment alone, steroid therapy alone, systemic broad spectrum antibiotic therapy alone, topical broad spectrum antibiotic therapy alone, vitreous biopsy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) L V Prasad Eye Institute India 2020-11-26 CTRI/2020/11/029346 Phase Not Applicable Not yet recruiting 1 20 Dr Sameera Nayak 2020-11-30
PCOVID: Clarithromycin in post Covid-19 parenchymal organizing pneumonia Coronavirus disease 19 infection, Respiratory disease, Viral pneumonia anti-tussive medication therapy alone, bronchodilator therapy alone, clarithromycin alone, mucolytics therapy alone, oral anti-fibrotic therapy alone, oral corticosteroid therapy alone, supplementary micronutrient therapy alone, clarithromycin plus oxygen Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Sri Ramachandra Hospital, Chennai India 2020-11-25 CTRI/2020/11/029305, PCOVID Phase 2 Clinical Not yet recruiting 1 120 Irfan Ismail Ayub 2020-12-01
The Efficacy and Safety of SCTA-01 in Hospitalized Patients With Severe COVID-19 Coronavirus disease 19 infection Best supportive care alone, SCTA-01 alone COVID19 Spike glycoprotein inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sinocelltech Ltd 2021-02-10 2021-10-10 NCT04644185, SCTA01-B301 Phase 2/Phase 3 Clinical Not yet recruiting 0 8 Months 795 Ji Qi, PhD, Zhanghua Lan, PhD 2020-11-30
Effectiveness of Pulmonary Rehabilitation Program in Patients With SARS-CoV-2 Pneumonia Anxiety disorder, Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory tract infection, Viral pneumonia alternate breathing alone, diaphragmatic breathing alone, early-mobilization and progressive ambulation alone, instructional exercise videos alone, joint ROM exercise alone, peripheral muscle strengthening exercises alone, pulmonary Rehabilitation program alone, pursed-lip breathing alone, respiratory muscle exercises alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sisli Etfal Hospital Turkey 2020-06-30 2021-01-31 2857, NCT04642040 Phase Not Applicable Recruiting 1 7 Months 100 Ali Sahillioglu, MD, Enes Efe Is, MD 2020-11-30
Comparative Effectiveness of IIMR Versus CDSMP Bipolar disorder, Cardiac failure, Cardiovascular disease, Chronic obstructive pulmonary disease, Coronavirus disease 19 infection, Depression, Diabetes mellitus, Drug dependence, Hyperlipidemia, Hypertension, Obesity, Respiratory disease, Schizoaffective disorder, Schizophrenia Integrated Illness Management and Recovery alone, Stanford Chronic Disease Self-Management Program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dartmouth-Hitchcock Medical Center Patient Centered Outcome Research Institute US 2019-09-02 2024-03-31 D19103 31245, NCT03966872 Phase Not Applicable No longer recruiting 2 54 Months 600 Sarah Pratt 2020-12-01
Preoperative Covid-19 Screening In Otorhinolaryngolagy, Head And Neck Elective Surgery Coronavirus disease 19 infection, Surgical procedure Otorhinolaryngolagy alone Hospital Ampang Malaysia 2020-11-26 2020-12-31 57395, NMRR-20-2530-57395 Phase Not Applicable Status not specified 1 1 Month Dr NOR AZIRAH BINTI SALAHUDDIN 2020-11-30
The Role of Hemoperfusion as a Countermeasure for Cytokine Storm in COVID-19 Patients Admitted in a Public Tertiary Hospital in Davao City Coronavirus disease 19 infection Southern Philippines Medical Center Philippines 2020-03-01 PHRR201120-003164 Phase Not Applicable Not yet recruiting 1 Nian Joy T. Ibot, MD 2020-11-30
Development and Validation of Clinical Scoring for Predicting In-Hospital 30-day Mortality Among COVID-19 Patients in University of the Philippines – Philippine General Hospital: A Retrospective, Cohort Study Coronavirus disease 19 infection Philippine General Hospital Philippines 2020-08-10 2020-11-10 PHRR201120-003161 Phase Not Applicable No longer recruiting 1 3 Months Anna Flor Malundo, MD, Dr. Regina P. Berba MD, Karla Kristel A. Banares, MD, Karla Kristel Banares, Maria Sonia Salamat, MD, Marissa M. Alejandria, MD 2020-11-30
Tele-monitoring of COVID-19 Survivors for Long-Term Impacts Coronavirus disease 19 infection Custom-designed miniaturized monitoring system alone, Tele-monitoring alone, video-conferencing sessions alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Manitoba Function Four Ltd 2020-12-01 2021-11-01 B2020:114 (HS24395), NCT04644341 Phase Not Applicable Not yet recruiting 0 11 Months 20 Zahra Moussavi, Ph.D. 2020-11-30
Characteristics of novel coronavirus pneumonia (COVID-19) patients with mild nucleic acid in hospital for over 30 days Coronavirus disease 19 infection, Viral pneumonia Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) People's Hospital of Shapingba District, Chongqing City Chongqing Science and Technology Commission China 2020-09-30 2021-08-31 ChiCTR2000040179 Phase Not Applicable Not yet recruiting 1 11 Months 170 Huang Zi-Yang 2020-11-30
Safety and Pharmacokinetics of a Novel Niclosamide Solution in Combination With Camostat Coronavirus disease 19 infection niclosamide alone, camostat mesylate plus niclosamide Serine protease inhibitor, Transmembrane serine protease 2 inhibitor, Trypsin inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Charite Research Organisation Bayer AG Germany 2020-11-02 2021-05-31 201767, NCT04644705, NIC-002 Phase 1 Clinical Recruiting 1 6 Months 28 Frank D Wagner, Prof. Dr. med., Maximilian Posch, Dr. med. 2020-11-30
NeuroCovid: WHO Covid19- Neurological Abnormalities in SARS-CoV-2 ICU Patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Clermont-Ferrand France 2020-10-13 2021-08-13 NCT04643548, NEUROCOVID-RNI 2020 GODET, NeuroCovid Phase Not Applicable Recruiting 1 10 Months 20 Benjamin Rieu, Lise Laclautre, Thomas Godet 2020-12-02
A phase II study to evaluate safety and effectiveness of IND-02 capsules in patients who are hospitalized SARS-CoV2 positive patients with mild to moderate COVID-19 at COVID management centers offering ayurvedic care Coronavirus disease 19 infection IND-02 alone, standard of care treatment alone ApoB editing catalytic polypeptide 3G modulator, HIV gp120 protein modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) IQVIA RDS (India) Pvt Ltd, Indus Biotech Pvt Ltd India 2020-11-30 CTRI/2020/11/029328, IND02-ORAL-COVID-19 Version 1.0 Phase 2 Clinical Not yet recruiting 5 118 Dr Ajay Javeri, Dr Amlendu Yadav, Dr Amol Laxmanrao Dange, Dr Jaya Prakash Appajigol, Dr Shrikant Deshpande, Suneela Thatte 2020-11-30
Differential Leukocyte Count and Covid-19 Diagnosis Coronavirus disease 19 infection CLDC algorithm alone, Differential leukocyte count (CLDC) device alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Istituto Neurologico Mediterraneo NEUROMED Italy 2020-12-31 2021-05-31 DEP_042020, NCT04643860 Phase Not Applicable Not yet recruiting 2 5 Months 1000 Licia Iacoviello 2020-12-01
Mask Adhesive Institutional Study Coronavirus disease 19 infection, Respiratory failure AF531 non-invasive ventilation mask (Philips) alone, PerformaTrak non-invasive ventilation mask (Philips) alone, mask adhesive (Philips) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Royal Philips Electronics US 2020-11-17 2020-12-17 NCT04644276, SRCHRCMASK ADHESIVE 2020_11130 Phase Not Applicable Not yet recruiting 1 1 Month 30 Robert Doekel, Wes Booth 2020-11-30
Telerehabilitation Following Meniscectomy Coronavirus disease 19 infection, Knee injury knee exercises alone, meniscectomy alone, proprioception and balance training alone, telerehabilitation therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) NYU Langone Health US 2020-12-01 2022-12-01 20-01584, NCT04644640 Phase Not Applicable Not yet recruiting 1 24 Months 60 Eoghan Hurley, MB, BCh, MCh, Eric Strauss, MD, Guillem Gonzalez-Lomas, MD, Kirk Campbell, MD, Laith Jazrawi, MD, Michael Alaia, MD 2020-11-26
Apprehensions and challenges faced by dentists during Covid-19 pandemic Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Manipal College of Dental Sciences India 2020-12-02 CTRI/2020/11/029335 Phase Not Applicable Not yet recruiting 1 189 Dr Sunitha Carnelio, Muskaan Chichra 2020-11-30
Improving Thinking in Everyday Life After Covid-19 Cognitive disorder, Coronavirus disease 19 infection instrumental activities of daily living shaping alone, speed of processing training alone, transfer package alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Alabama at Birmingham US 2020-11-01 2024-11-30 IRB-300002814C, NCT04644172 Phase 1/Phase 2 Clinical Recruiting 1 49 Months 40 Edward Taub, Edward Taub, Ph.D., Staci McKay 2020-12-01
Brief Video Interventions for Depression Coronavirus disease 19 infection, Depression video-based intervention on behavioral emotion regulation skill alone, video-based intervention on cognitive emotion regulation skill alone, video-based intervention on interpersonal emotion regulation skill alone, video-based intervention on three emotion regulation skill alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ohio State University US 2020-11-30 2020-11-30 2020B0326, NCT04643964 Phase Not Applicable Recruiting 1 501 Daniel R Strunk, Ph.D., Graham C Bartels, B.S., Jennifer S Cheavens, PhD, Robert J Zhou, B.A. 2020-11-30
Effects of a Biomechanical-based Tai Chi Program on Gait and Posture in People With Parkinson's Disease Coronavirus disease 19 infection, Parkinsons disease Tai Chi training alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Ottawa Canada 2021-01-31 2021-12-31 H-01-19-2284, NCT04644367 Phase Not Applicable Not yet recruiting 1 11 Months 40 Jing Xian Li, PhD., Nok-Yeung Law, Nok-Yeung Law, M.Sc. 2020-12-01
Using Travelan to Boost Immune Response in Vitro to COVID-19 Coronavirus disease 19 infection Travelan alone Healthy volunteers accepted, Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hadassah Medical Organization Israel 2020-11-01 2020-12-31 HEALTHYTRAVELANCOV19- HMO-CTIL, NCT04643561 Phase 1/Phase 2 Clinical No longer recruiting 1 2 Months 5 Assaf Potruch, MD 2020-11-30
The Doctors for Coronavirus Prevention Project Thanksgiving Messaging Campaign Coronavirus disease 19 infection Facebook Ads alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Bureau of Economic Research Inc Harvard University, Massachusetts General Hospital, Massachusetts Institute of Technology, Stanford University, Yale University US 2020-11-14 2021-11-26 2003000118A010, NCT04644328 Phase Not Applicable Not yet recruiting 1 12 Months 20000000 Esther Duflo 2020-11-26
Management of Type 1 Supracondylar Humeral Fractures Coronavirus disease 19 infection, Upper limb fracture long arm soft casting alone Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs) University of British Columbia Lady Cilento Children's Hospital Canada 2021-01-31 2023-01-31 H20-02942, NCT04642807 Phase Not Applicable Not yet recruiting 1 24 Months 52 Anthony Cooper, Anthony Cooper, FRCSC, Harpreet Chhina, MSc 2020-12-01
Convalescent Plasma Transfusion in Severe COVID-19 Patients in Jamaica Coronavirus disease 19 infection convalescent plasma alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of the West Indies Jamaica 2020-12-01 2021-12-01 ECP/195,19/20, NCT04644198 Phase 2 Clinical Not yet recruiting 1 12 Months 30 Gilian G Wharfe, Giliian G Wharfe, MB, BS, DM, Tomlin Paul 2020-11-30
COVID-OISE: Longitudinal Follow-up of a Population Cohort in a French City With High SARS-CoV-2 Circulation in Early 2020 (COVID 19) Coronavirus disease 19 infection Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institut Pasteur France 2020-11-13 2023-11-01 2020-060, COVID-OISE, NCT04644159 Phase Not Applicable Recruiting 2 35 Months 2000 Aymar KOFFI, Dr, Bruno HOEN, Pr, Cécile DURU, Dr, Laurie Pinaud, Marie-Noëlle UNGEHEUER,, Sandrine Fernandes Pellerin 2020-12-01
Develop homeopathic Nosodes for Immunity Against COVID 19 Coronavirus disease 19 infection nosode alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Council for Research in Homeopathy Ministry of Ayush, National Cancer Institute, Jhajjar, AIIMS India 2020-12-10 CTRI/2020/11/029399 Phase 1 Clinical Not yet recruiting 1 20 Dr Naval Kumar Verma, Dr Sushma Bhtanagar 2020-11-28
Palliative Care in COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kasturba Medical College and Hospital India 2020-12-07 CTRI/2020/11/029398 Phase Not Applicable Not yet recruiting 1 50 Seema Rajesh Rao 2020-11-28
Changing Trends in Presentation of Trauma Patients during Nationwide lockdown for COVID-19 Coronavirus disease 19 infection, Injury Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) HBTMC and Dr RN Cooper Municipal General Hospital India 2020-12-01 CTRI/2020/11/029297 Phase Not Applicable Not yet recruiting 1 100 Vipul Versi Nandu 2020-12-01
Study to Assess Adverse Events and How Intravenous ABBV-47D11 Moves Through the Body of Adult Participants Hospitalized With Coronavirus Disease 2019 (COVID-19) Coronavirus disease 19 infection, Lower respiratory tract infection ABBV-47D11 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) AbbVie Inc US 2020-11-27 2021-05-01 2020-005203-39, M20-404, NCT04644120 Phase 1 Clinical Not yet recruiting 11 5 Months 24 ABBVIE CALL CENTER, AbbVie Inc. 2020-11-27
Safety of an aerosol having as its active ingredient 8.4% sodium bicarbonate and xylitol 5% when administered to the nasopharynx and oropharynx Coronavirus disease 19 infection, Influenza virus infection Variable regimens including benzalkonium chloride , glycerine , propylene glycol , sodium bicarbonate , xylitol Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) DR BHARAT MODY, Myself Health Check Ltd Welcare Hospital India 2020-12-01 CTRI/2020/11/029396 Phase 2 Clinical Not yet recruiting 1 325 Dr Kshitij Mody, Dr Manoj Parmar, Dr Vidhi Hingu 2020-12-02
Semen Parameters and COVID-19 in Infertile Men Coronavirus disease 19 infection, Male infertility reverse transcriptase polymerase chain reaction test alone, spermiogram analysis alone Male, Young Adults (18-44 yrs) Ankara City Hospital Bilkent Turkey 2020-01-07 2020-10-10 E1-20-1237, NCT04643522 Phase Not Applicable Completed 1 9 Months 21 Erdem Koc 2020-12-01
Precautionary measure during surgical process during COVID-19 pandemic around the globe Coronavirus disease 19 infection FFP-2 mask alone, N-95 mask alone, nasal prongs alone, oxygen therapy alone, suction cannula alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Harsiddhi Cosmetic and Plastic Surgery Hospital India 2020-12-01 CTRI/2020/11/029394 Phase Not Applicable Not yet recruiting 1 30 Dr Pradipkumar Raghuvirsinh Atodaria 2020-12-02
Circulatory Coherence in COVID-19 and Non-COVID-19 Patients With Sepsis Coronavirus disease 19 infection, Sepsis microcirculation recording alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Hradec Kralove Czech Republic 2020-02-01 2021-12-31 FNHK_IGS_8144, NCT04644302 Phase Not Applicable Recruiting 1 23 Months 25 David Astapenko, M.D., Pavel Dostal, M.D., Ph.D., MBA, Vladimir Cerny, Vladimir Cerny, prof. 2020-12-01
Anakinra in the Management of COVID-19 Infection Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia Standard of care alone, anakinra alone Type I IL-1 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hamad Medical Corp Qatar 2020-10-30 2021-10-30 MRC-05-140, NCT04643678 Phase 2/Phase 3 Clinical Recruiting 1 12 Months 80 Dr. Eman Elmekaty, PharmD 2020-12-09
Iodine treatment Coronavirus infection Coronavirus disease 19 infection iodine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Maxima Medisch Centrum Veldhoven Netherlands 2020-07-14 01-04-2020, 2020-001852-16 Phase 2 Clinical Recruiting 1 224 reumatology department 2020-11-27
PoliCOV: Police COVID-19 Serosurvey Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Bern Blutspendedienst SRK Bern AG Switzerland 2021-01-31 2022-06-30 2020-02650, NCT04643444, PoliCOV Phase Not Applicable Not yet recruiting 2 17 Months 1000 Parham Sendi, MD 2020-12-01
COVIDGEN: Genetic Predisposition to Severe Forms of COVID-19 (SARS-CoV2 Infection) Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hospices Civils De Lyon France 2020-12-01 2021-12-01 69HCL20_1072, COVIDGEN, NCT04644146 Phase Not Applicable Recruiting 1 12 Months 40 Alain CALENDER, MD 2020-11-27
Inflammatory Markers and Hematological Indices in the Prediction of Severity of COVID-19: A Single Center Study in Southern Philippines Coronavirus disease 19 infection Southern Philippines Medical Center Philippines 2020-11-30 2021-04-30 PHRR201117-003152 Phase Not Applicable Not yet recruiting 1 5 Months Meccar Moniem Haradji Elino 2020-11-27
The effect of selenium in patients with COVID-19 Coronavirus disease 19 infection selenium alone Ghoum University of Medical Sciences Qom University of Medical Science Iran 2020-03-20 2020-06-20 IR.MUQ.REC.1398.161, IRCT20160919029870N3 Phase 3 Clinical Completed 1 3 Months 80 Hamed Shafiee 2020-11-27
An interventional study on the assessment of QT interval prolongation under hydroxychloroquine/azithromycin association among inpatients with SARS-CoV-2 lower respiratory tract infection Coronavirus disease 19 infection, Lower respiratory tract infection azithromycin plus hydroxychloroquine Centre Hospitalier Universitaire De Nice Phase 2 Clinical Status not specified 0 73 2020-11-26
Health-related Quality of Life among Filipino Breast Cancer Patients referred for Radiotherapy using a Validated, Culture-Specific tool in a State Referral Center during the COVID-19 Pandemic Breast tumor, Coronavirus disease 19 infection Radiotherapy alone Philippine General Hospital Philippines 2020-06-18 2020-12-18 PHRR201117-003126 Phase Not Applicable Recruiting 1 6 Months Benedict Mihangel P. Crisostomo 2020-12-02
Repeat Computed Tomography Simulation among Head and Neck Cancer Patients experiencing Delayed Radiation Therapy in a State Referral Center during the COVID-19 Pandemic Coronavirus disease 19 infection, Head and neck tumor Computed Tomography (CT) simulation alone, external beam radiotherapy alone Philippine General Hospital Philippines 2020-06-18 2020-12-18 PHRR201117-003125 Phase Not Applicable Recruiting 1 6 Months Benedict Crisostomo 2020-11-27
A Phase II/III Study of Sargramostim Coronavirus disease 19 infection, Viral pneumonia sargramostim (inhalant, COVID-19), Nobelpharma alone, standard treatment alone CSF-1 agonist, GM-CSF receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Japanese Ancestry Nobelpharma Co Ltd Japan 2020-11-24 2021-04-30 NCT04642950, NPC-26-1 Phase 2/Phase 3 Clinical Not yet recruiting 4 5 Months 60 Masaki Taniguchi 2020-11-30
EPIC-19: Application of Convalescent Plasma in the Treatment of SARS CoV-2 Disease (COVID-19) With Evaluation of Therapy Effectiveness Coronavirus disease 19 infection, Respiratory distress syndrome anti SARS-CoV-2 convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Wroclaw Medical University Medical Research Agency (Agencja Badań Medycznych) Poland 2020-12-01 2022-05-01 2020.ABM.COVID19.0005, EPIC-19, NCT04642014 Phase 2 Clinical Not yet recruiting 1 17 Months 500 Jarocław Dybko, PhD, Siddarth Agrawal, PhD 2020-11-27
PEER MHEALTH: The impact of WASH text messages and environmental cues intervention on hand hygiene practice among healthcare workers in the greater Kampala metropolitan area, Uganda Coronavirus disease 19 infection, Sepsis Glo Germ gel alone, environmental cues intervention alone, mhealth water, sanitation and hygiene text message intervention alone, simple hand washing facility usage alone National Academy of Sciences Uganda 2020-01-01 2021-09-30 8-187, ISRCTN98148144, PEER MHEALTH Phase 2 Clinical Not yet recruiting 1 21 Months 450 Dr Richard Mugambe 2020-11-27
Mortality in Patients With Severe COVID-19 Pneumonia Who Underwent Tracheostomy Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia mechanical ventilation alone, percutaneous tracheostomy alone, surgical tracheostomy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Chile Chile 2020-03-03 2021-11-30 65/20, NCT04642703 Phase Not Applicable Recruiting 1 20 Months 100 Abraham Gajardo, MD, Carlos Romero, MD 2020-11-28
UK-REACH: United Kingdom research study into ethnicity and COVID-19 outcomes in healthcare workers Coronavirus disease 19 infection Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Leicester National Institute for Health Research (NIHR), United Kingdom Research & Innovation UK 2020-08-01 2045-08-01 IRAS 288316, ISRCTN11811602, SPONSOR REFERENCE 0801, UK-REACH Phase Not Applicable Recruiting 1 300 Months 1530180 Dr Claire Garwood, Dr Pareek 2020-11-27
Clinical Trial of the Immunogenicity, Safety, and Efficacy of the Gam-COVID-Vac Vaccine Against COVID-19 in Venezuela Coronavirus disease 19 infection Sputnik V alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gamalei Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation Collaborator Ministerio del Poder Popular para la Salud de la República Bolivariana de Venezuela Venezuela 2020-11-30 2021-12-31 01V-GAM-COVID-VAC-2020, NCT04642339 Phase 3 Clinical Not yet recruiting 1 13 Months 2000 Alexis H García Piñero, MD 2020-12-10
A pilot, randomized, controlled trial examining the feasibility, acceptability and preliminary efficacy of an internet-delivered cognitive bias modification to reduce co-occurring social anxiety and alcohol use in young Australians Alcoholism, Anxiety disorder, Coronavirus disease 19 infection, Social phobia Approach Bias Modification alone, Interpretation Bias Modification (IBM) alone, treatment as usual alone Young Adults (18-44 yrs), Oceanic Ancestry University of Sydney Australian Rotary Health, National Health and Medical Research Council Australia 2021-01-04 ACTRN12620001273976, U1111-1252-8422 Phase Not Applicable Not yet recruiting 1 90 Dr Katrina Prior 2020-11-29
AIR: Air for Infant Resuscitation Birth complication, Coronavirus disease 19 infection, Respiratory disease Infants (6-23 months) Royal Hospital for Women, University of New South Wales Malaysia, Australia, US, Singapore, India, Guatemala, Indonesia, China, Spain, Vietnam, Canada 2020-12-01 2021-09-01 ACTRN12620001252909, AIR Phase Not Applicable Not yet recruiting 17 9 Months 200 A/Prof Ju-Lee Oei, Mr James Sotiropoulos 2020-11-29
A trial to evaluate aprotinin (inhalation therapy), ChemRar High Tech Center for the treatment of patients with severe COVID-19 Coronavirus disease 19 infection aprotinin (inhalation therapy), ChemRar High Tech Center alone ChemRar High Tech Center Phase Not Applicable Status not specified 0 2020-11-25
A trial to evaluate aprotinin (intravenous), ChemRar High Tech Center for the treatment of patients with moderate COVID-19 Coronavirus disease 19 infection aprotinin (intravenous), ChemRar High Tech Center alone ChemRar High Tech Center Phase Not Applicable Status not specified 0 2020-11-25
A trial to evaluate aprotinin (nasal spray) for the prevention of coronavirus infection Coronavirus disease 19 infection aprotinin (nasal spray) alone ChemRar High Tech Center Phase Not Applicable Status not specified 0 2020-11-25
The Loddon Mallee Healthcare Worker COVID-19 Study Anxiety disorder, Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bendigo Health Care Group, La Trobe University Victorian State Government Australia 2020-11-27 2023-08-31 ACTRN12620001269921 Phase Not Applicable Not yet recruiting 1 33 Months 4000 A/Prof Mark McEvoy, Dr Carol Parker 2020-11-29
Contrast Enhanced Ultrasound in COVID-19 Coronavirus disease 19 infection, Vascular disease contrast-enhanced ultrasound alone, sodium chloride plus sulphur hexafluoride microbubble ultrasound agent, Bracco Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) Childrens Hospital of Philadelphia US 2020-12-31 2022-12-31 20-017501, NCT04640038 Phase 3 Clinical Recruiting 1 24 Months 30 Luis Tierradentro, MD, Misun Hwang, Misun Hwang, MD 2020-12-08
CHAT: Intravenous immunoglobulin rich in neutralising antibodies to SARS-CoV-2 as a passive immunity modality in healthy individuals at risk of infection with COVID-19: an open-label, active control, Phase I/II Study Coronavirus disease 19 infection hyperimmune IG (HIVIG) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Aegros Ltd Australia 2020-12-01 2021-10-01 ACTRN12620001249943p, AEG-CTP-01, CHAT, U1111-1261-2497 Phase 1/Phase 2 Clinical Not yet recruiting 2 10 Months 30 A/Prof Roderick Clifton-Bligh, Dr Guy Gavagna 2020-12-08
A study to assess safety and efficacy of COR-101 for the potential use of COVID-19 Coronavirus disease 19 infection COR-101 alone Corat Therapeutics GmbH 2021-01-01 Phase Not Applicable Status not specified 0 2020-12-07
Efficacy and Safety of Ovotransferrin in COVID-19 Patients Coronavirus disease 19 infection, Viral pneumonia ovotransferrin alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone Palermo Italy 2020-12-01 2021-03-30 20201116, NCT04643054 Phase Not Applicable Not yet recruiting 1 3 Months 100 Antonio Cascio, Antonio Cascio, MD, Antonio Cascio, MD, PhD 2020-11-26
Virtual models for delivery of exercise training in Cystic Fibrosis (CF): an evaluation of patient engagement and feasibility Coronavirus disease 19 infection, Cystic fibrosis online exercise classes alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The Prince Charles Hospital Australia 2020-12-31 2021-04-30 ACTRN12620001237976p Phase Not Applicable Not yet recruiting 1 4 Months 24 Miss Kelly Burgess 2020-11-29
COROBIOCHIC: Cardiac Biomarkers and Mortality in Critically Ill Patients With SARS-CoV-2 (COVID-19) Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Montpellier France 2020-02-01 2020-06-30 COROBIOCHIC, NCT04641988, RECHMPL20-0625 Phase Not Applicable Completed 1 5 Months 111 Romaric Larcher, MD, PharmD, MSc 2020-11-26
TBA: Evolution of diaphragm and abdominal muscle thickness in ventilated COVID-19 patients Coronavirus disease 19 infection, Muscle weakness Ultrasound alone, mechanical ventilation alone Amsterdam UMC Netherlands 2020-11-09 2021-01-15 2017.056, NL9053, TBA Phase Not Applicable Recruiting 1 2 Months 40 Mark Haaksma 2020-11-26
Light on COVID-19 Coronavirus disease 19 infection Respiratory physiotherapy alone, conventional treatment alone, infrared LED alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Anhembi Morumbi Brazil 2020-10-04 36988320.5.0000.5492, 4.269.568, 4.317.859, CAAE 37010820.0.0000.5492, RBR-2z5t7z, U1111-1261-1981 Phase 1 Clinical Recruiting 1 40 Pâmela Camila Pereira 2020-12-08
A phase Ib, open-label, single-arm, investigator-initiated trial to evaluate the safety and efficacy of motixafortide in the treatment of patients suffering from acute respiratory distress syndrome (ARDS) secondary to COVID-19 and other respiratory viral infections Coronavirus disease 19 infection, Respiratory distress syndrome, Viral respiratory tract infection motixafortide alone CXCR4 chemokine antagonist BioLineRx Ltd Israel 2020-11-18 Phase 1b Clinical Recruiting 1 25 Dr Yasmin Maor 2020-11-25
Analysis of motor response time, electromyography and muscle strength in volunteers from the group at risk for covid-19 submitted to a home exercise protocol: randomized, controlled, clinical trial, cross over Coronavirus disease 19 infection PhysioPlay alone, electromyography alone, home exercise alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Federal University of Alfenas Brazil 2021-04-05 36899320.7.0000.5142, 4.355.736, RBR-2fvw6v, U1111-1257-6957 Phase Not Applicable Not yet recruiting 1 20 Leonardo Cesar Carvalho 2020-11-30
LYMPHO-Cov-2: Clinical and Immunological Evolution of COVID-19 Occurring in a Context of Non-Hodgkin Lymphoma B-cell lymphoma, Coronavirus disease 19 infection, Non-Hodgkin lymphoma monoclonal anti-CD20 antibodies therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Versailles University Hospital France 2020-12-15 2021-09-16 LYMPHO-Cov-2, NCT04641806, P20/21-LYMPHO-COV-2 Phase Not Applicable Not yet recruiting 1 9 Months 120 Caroline BESSONHospital 2020-11-26
BCG-COVID-RCT: BCG to Reduce Absenteeism Among Health Care Workers During the COVID-19 Pandemic (EDCTP) Coronavirus disease 19 infection BCG-Denmark alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Southern Denmark Bandim Health Project, Centro de Investigacao em Saude de Manhica, European and Developing Countries Clinical Trials Partnership, Instituto De Higiene E Medicina Tropical, The University of Cape Verde Mozambique, Cape Verde, Guinea-Bissau 2020-12-03 2022-03-31 BCG-COVID-RCT, BCG-COVID-RCT, NCT04641858 Phase 4 Clinical Recruiting 3 15 Months 1050 Amabélia Rodrigues, MD, PhD, Christine Stabell Benn, Professor, Helio Mucavele, MD, Inês Fronteira, PhD, Isabel Inês Araújo, Professor, Maria da Luz Lima, Pedro Aide, MD, MSc, PhD, Peter Aaby, DMSc 2020-12-07
INNOVATE: Safety, Immunogenicity and Efficacy of INO-4800 for COVID-19 in Healthy Seronegative Adults at High Risk of SARS-CoV-2 Exposure Coronavirus disease 19 infection CELLECTRA 2000 device alone, INO-4800 alone, electroporation alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Inovio Pharmaceuticals Inc US Department of Defense, US Government US 2020-11-30 2022-09-30 COVID19-311, INNOVATE, INNOVATE, NCT04642638 Phase 2/Phase 3 Clinical Recruiting 16 22 Months 6578 Barbara Rizzardi, Christopher Chambers, Corey Anderson, Donna DeSantis, Ernie Riffer, Inovio Call Center, Jeffrey Rosen, John Ervin, Louis Saravolatz, Mammen P. Mammen Jr, M.D., FACP, FIDSA, Mark Adams, Melinda Hamer, Michael Jacobs, Olutola Adetona, Pablo Tebas, Patrick Yassini, Principal Investigator Christopher Chambers, Principal Investigator Melinda Hamer, Prinicipal Investigator Barbara Rizzardi, Prinicipal Investigator Corey Anderson, Prinicipal Investigator Donna DeSantis, Prinicipal Investigator Ernie Riffer, Prinicipal Investigator Jeffrey Rosen, Prinicipal Investigator Louis Saravolatz, Prinicipal Investigator Michael Jacobs, Prinicipal Investigator Olutola Adetona, Prinicipal Investigator Patrick Yassini, Prinicipal Investigator Sady A. Alpizar, Prinicipal Investigator Vickie Miller, Program Manager Amanda Bear, Program Manager Barbara Bradshaw, Program Manager Ginger Switzer, Sady A. Alpizar, Vickie Miller 2020-12-09
COVID-19 in Home Healthcare Coronavirus disease 19 infection home health care alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) University Hospital, Linkoeping Sweden 2020-05-02 2020-10-10 HOME HEALTHCARE 2020, NCT04642196 Phase Not Applicable Completed 1 5 Months 155 Lena Nilsson 2020-11-27
Study Investigating the Effects of UVC Beam and Laser Beam Therapy According to Standard Therapy in Patients With Covid-19 Diagnosis Coronavirus disease 19 infection, Dyspnea, Respiratory disease, Viral pneumonia Turkish Beam-Selective UV device (Rd Global Arastirma Gelistirme Saglik Ilac Insaat Yatirimlari AS) alone, anitibiotic therapy alone, antimalarial therapy alone, antiviral therapy alone, ultraviolet C application alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Rd Global Arastirma Gelistirme Saglik Ilac Insaat Yatirimlari Sanayi Ve Ticaret Anonim Sirketi Gazi University Turkey 2020-06-26 2021-05-04 MD2020/001, NCT04642326 Phase Not Applicable No longer recruiting 1 10 Months 50 Hikmet Selcuk Gedik 2020-11-27
Investigation of the Safety and Efficacy of Oxygen Administration over a Surgical Facemask Coronavirus disease 19 infection Surgical Facemask alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fukuoka Children's Hospital Japan 2020-11-24 UMIN000042524 Phase Not Applicable Recruiting 1 20 Keiichiro Mizuno 2020-12-02
Response of patients and chest X-ray improvement after Remdesivir Coronavirus disease 19 infection remdesivir alone COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kasturba Medical College, Kasturba hospital India 2020-12-04 CTRI/2020/11/029266 Phase Not Applicable Not yet recruiting 1 126 Vishal Shanbhag 2020-11-26
A trial to evaluate saliva-based test detect the presence of antibodies to SARS-CoV-2 Coronavirus disease 19 infection saliva-based test alone Johns Hopkins Bloomberg School of Public Health Phase Not Applicable Status not specified 0 2020-11-25
To study the long-term ill effects of COVID-19 infection in old age people Coronavirus disease 19 infection Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sri Ramachandra Institute of Higher Education and Research India 2020-12-01 CTRI/2020/11/029264 Phase Not Applicable Not yet recruiting 1 400 Dr Sathyamurthy 2020-11-26
The Efficacy, Safety and Immunogenicity Study of Inactivated SARS-CoV-2 Vaccine for Preventing Against COVID-19 Coronavirus disease 19 infection Inactivated SARS-CoV-2 Vaccine (Vero Cell), IMBCAMS alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chinese Academy of Medical Sciences Malaysia, Brazil 2020-12-01 2022-03-31 20200404, 57143, NCT04659239, NMRR-20-2514-57143 Phase 3 Clinical Not yet recruiting 5 16 Months 3000 Adilson JW Cavalcante, PhD, Jing Pu, PhD, Qihan Li, PhD, Yasmin binti Mohamed Gani, PhD 2020-12-10
Vitamin D and Zinc Supplementation for Improving Treatment Outcomes Among COVID-19 Patients in India Coronavirus disease 19 infection Vitamin D3 (cholecalciferol) alone, Zinc (zinc gluconate) alone, Vitamin D3 (cholecalciferol) plus Zinc (zinc gluconate) Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Harvard TH Chan School of Public Health Foundation for Medical Research, The University Health Network India 2020-12-07 2021-12-31 NCT04641195, VR3- 172649 Phase 3 Clinical Not yet recruiting 2 12 Months 700 Guaray Gupta, MD, Kevin Kain, MD, Wafaie W Fawzi, MBBS, MPH, MS, DrPH, Wafaie W Wafaie, MBBS, MPH, MS, DrPH 2020-11-30
A reasearch study to utilize the AIRx Health platform to monitor COVID-19 outpatients to better understand which patients deteriorate faster and require hospitalization Coronavirus disease 19 infection AIRx Health alone Stanford Medicine US Phase Not Applicable Status not specified 1 2000 2020-11-25
Associated factors for COVID-19 infection in Terengganu Coronavirus disease 19 infection Dungun District Health Office (Pejabat Kesihatan Daerah Dungun) Malaysia 2020-11-20 2020-12-20 57220, NMRR-20-2468-57220, PKDD2020/1 Phase Not Applicable Not yet recruiting 1 1 Month Dr Hafizuddin Bin Awang, Dr. Effah Leiylena Binti Yaacob 2020-12-11
Accuracy of POCUS ultrasound in detecting severity of confirmed symptomatic COVID-19 patients in MTC Coronavirus disease 19 infection point-of-care lung ultrasound alone Sultanah Bahiyah Hospital Malaysia 2020-11-17 2020-12-31 56961, NMRR-20-2480-56961 Phase Not Applicable Status not specified 1 1 Month Dr Fatahul Laham Mohamed, Ong Sheue Fen 2020-11-26
A clinical study on favipiravir in mild to moderate COVID-19 patients Coronavirus disease 19 infection favipiravir alone RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Glenmark Pharmaceuticals Ltd India 2020-11-30 CTRI/2020/11/029263, GPL/CT/2020/007/IV Version 2.0 Phase 4 Clinical Not yet recruiting 3 1200 Dr Saiprasad Patil, Rajesh Gaikwad 2020-11-26
Role of vitamin C in management of COVID 19 Coronavirus disease 19 infection vitamin C alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Medical Sciences Patna India 2020-11-20 CTRI/2020/11/029230 Phase 3 Clinical Not yet recruiting 1 80 DR VIJAY KUMAR 2020-11-26
Characterization of COVID-19 long-term immunity Coronavirus disease 19 infection 6 min walking respiratory function testing alone, serological testing alone, sit-to-stand respiratory function testing alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Bristol Medical Research Council UK 2020-08-01 2021-11-30 CPMS 47414, IRAS 289646, ISRCTN11946807 Phase Not Applicable Recruiting 1 16 Months 250 Dr Lewcock, Prof Timpson 2020-11-26
REGAIN: A randomized trial to assess the effects of physical and mental health rehabilitation for people recovering from COVID-19 Coronavirus disease 19 infection home-based rehabilitation program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospitals Coventry & Warwickshire NHS Trust NIHR Evaluation, Trials and Studies Coordinating Centre (NETSCC) UK 2020-09-01 2022-08-31 CPMS 46819, IRAS 288362, ISRCTN11466448, REGAIN Phase Not Applicable Not yet recruiting 1 24 Months 535 Ms Sharisse Alleyne 2020-11-25
Evaluation of stem cells treatment in Covid-19 patients Coronavirus disease 19 infection Mensenchymal Stem Cells alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Stemcorp Brazil 2020-11-19 4.167.621, A01224210603, CAAE: 32650720.1.0000.0068, RBR-4jh63b Phase 1/Phase 2 Clinical Recruiting 1 30 Eder Zucconi, Mariane Secco, Natassia Vieira Serafini 2020-11-25
TRISTARDS: A Study to Test Whether Different Doses of Alteplase Help People With Severe Breathing Problems Because of COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome alteplase alone, standard of care alone Tissue plasminogen activator stimulator Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Boehringer Ingelheim International GmbH Austria, Netherlands 2020-12-07 2022-09-01 0135-0347, 2020-002913-16, NCT04640194, TRISTARDS Phase 2/Phase 3 Clinical Not yet recruiting 2 20 Months 270 Boehringer Ingelheim, CT Disclosure & Data Transparency 2020-12-08
Dulce: HbA1c Pre and Post-Confinement in Latin American Children With Type 1 Diabetes Coronavirus disease 19 infection, Insulin dependent diabetes Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) Hospital General Puyo Argentina 2020-11-22 2021-04-22 0019, Dulce, NCT04640064 Phase Not Applicable Not yet recruiting 1 5 Months 500 Angela Figueroa Sobrero, MD, Carlos Del Aguila Villar, MD, Diana Gonzalez, MD, Edgar Mora, MD, Edit Scaiola, MD, Fabio Palacios Porta, MD, Franco Giraudo Abarca, MD, Julie Pelicand, MD, Kesia Granela, MD, Nicole Monteverde, MD, Valeria Hirschler 2020-11-26
Effect of the drug indomethacin in the treatment of COVID-19 patients Coronavirus disease 19 infection Standard care alone, indomethacin alone, proton pump inhibitor therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Indian Institute Of Technology Madras India 2020-07-27 2021-01-01 CR/20-21/ED/208/ALUM/002553​, ISRCTN11970082 Phase 2 Clinical Recruiting 2 5 Months 250 Dr Rajan Ravichandran, Prof KrishnaKumar 2020-11-25
Prognostic value of simple computer-aided quantitative chest CT analysis among known cases of COVID-19 pneumonia in Philippine General Hospital Coronavirus disease 19 infection, Viral pneumonia chest CT analysis alone Philippine General Hospital, University of the Philippines Philippines 2020-12-01 2021-03-01 PHRR201120-003166 Phase Not Applicable Completed 1 3 Months Mark Jerome G Mauricio 2020-11-25
Patient satisfaction with psychiatry services during the pandemic Coronavirus disease 19 infection, Psychiatric disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bhabha Atomic Research Centre Hospital India 2020-12-01 CTRI/2020/11/029236 Phase 4 Clinical Recruiting 1 347 Dr Saumitra Nemlekar 2020-11-24
MATCH: MAnaging The COVID-19 in Hemodialysis Coronavirus disease 19 infection, End stage renal disease Dialysis alone Healthy volunteers accepted Hospital Kuala Lumpur Malaysia 2020-12-01 2020-12-31 54601, MATCH, NMRR-20-2484-54601 Phase Not Applicable No longer recruiting 1 1 Month Dr NG YONG MUH 2020-11-25
Clinical Trial to Assess Safety and Immunogenicity of Gam-COVID-Vac Combined Vector Vaccine for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-Сov-2) Infection Coronavirus disease 19 infection Sputnik V alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry Dr Reddy's Laboratories Ltd, Sputnik LLC Gamalei Institute of Epidemiology and Microbiology, Max Neeman International, Russian Direct Investment Fund India 2020-12-31 2021-09-30 CTRI/2020/11/029234, NCT04640233, RDI-GCV-001, RDI-GCV-001 V3.0 Phase 2/Phase 3 Clinical Not yet recruiting 12 9 Months 1600 Akash Khobragade, MD, Asim Das, MD, Dr Anand Kawade, Dr Anil Purty, Dr Jayaprakash Appajigol, Dr Lalit Lakhwani, Dr Manish Kumar Jain, Dr Sandeep Kumar Gupta, Dr Saurabh Agarwal, Dr Shariq Anwar, Dr Shilpa Avarebeel, Dr Sidram Raut, Dr Sonika Newar, Dr Winsley Rose, Dr. Agam Shah, MD, Dr. Lalit Lakhwani, MD, Manish K Jain, MD, N K Arora, MD, S K Raut, MBBS, DIH, Saurabh Agarwal, MD 2020-12-10
A clinical study to assess safety and efficacy of baricitinib in addition to standard care in the treatment of patients hospitalized with COVID-19 pneumonia  Coronavirus disease 19 infection, Viral pneumonia baricitinib alone, standard care alone Jak1 tyrosine kinase inhibitor, Jak2 tyrosine kinase inhibitor BenevolentAI Ltd Biomedical Research Networking Center on Frailty and Healthy Aging (CIBERFES), Diamond Innovative Medicines Initiative, Experimental Cancer Medicine Centre Network, Instituto de Salud Carlos III, National Institute for Health Research (NIHR), National Institutes of Health, National Science Foundation, Swedish Research Council, The European Union Spain, UK, Italy Phase Not Applicable Status not specified 3 166 Professor Justin Stebbing 2020-11-24
Measurement of Quality of food intake, mental health status, and safety measures followed by the hospital support staff during COVID-19 Acute stress disorder, Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Manipal Academy of Higher Education, Welcomgroup Graduate School of Hotel Administration India 2020-11-24 CTRI/2020/11/029221 Phase Not Applicable Not yet recruiting 1 354 Apoorva Jain, Mrs Pallavi Mahesh Shettigar, P Vaishnavi Yadav 2020-11-25
Assessing knowledge, attitudes, perceptions, and practices surrounding COVID-19 and tuberculosis (TB) in Kajang prison staff: a survey study in Kuala Lumpur Coronavirus disease 19 infection Healthy volunteers accepted University of Malaya Malaysia 2021-01-01 2021-08-15 57106, NMRR-20-2483-57106 Phase Not Applicable Status not specified 1 7 Months Dr. NUR AFIQAH BINTI MOHD SALLEH 2020-11-30
COVID-KEDAH: COVID-19 Infection among Healthcare Worker in Kedah Coronavirus disease 19 infection Healthy volunteers accepted Ministry of Health, Malaysia Malaysia 2020-11-17 2021-04-30 57138, COVID-KEDAH, NMRR-20-2478-57138 Phase Not Applicable Status not specified 1 5 Months Dr. ROSIDAH BINTI OMAR 2020-11-30
ACTT-4: Adaptive COVID-19 Treatment Trial 4 Coronavirus disease 19 infection baricitinib plus remdesivir COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, Jak1 tyrosine kinase inhibitor, Jak2 tyrosine kinase inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Allergy and Infectious Diseases US 2020-11-24 2021-06-30 20-0006 ACTT-4, ACTT-4, NCT04640168 Phase 3 Clinical Recruiting 12 7 Months 1500 20-0006 Central Contact 2020-12-11
Prone Position for Nonintubated Patients With COVID-19 and Hypoxemic Respiratory Failure Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia Prone position alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Pontificia Universidad Catolica De Chile Chile 2020-07-06 2020-09-16 0001, NCT04641182 Phase Not Applicable Completed 1 2 Months 66 2020-11-25
An observational, retrospective study to evaluate the role of thromboprophylaxis regimens on the occurrence of pulmonary embolism in COVID-19 patients Coronavirus disease 19 infection CT pulmonary angiography alone, enoxaparin sodium alone, heparin alone, thromboprophylaxis alone Low molecular weight heparin Universite Libre de Bruxelles Phase Not Applicable Status not specified 0 2020-11-24
Coping during COVID-19: peer-delivered training to improve adolescent wellbeing Coronavirus disease 19 infection, Psychiatric disorder coping based COVID-19 online training alone Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs) University of Oxford Westminster Foundation UK 2020-10-01 2021-03-30 ISRCTN77941736 Phase Not Applicable No longer recruiting 1 5 Months 120 Dr Gabriela Pavarini 2020-12-07
Preventive trial of Homoeopathic medicines in COVID-19 Coronavirus disease 19 infection general hygienic measure teaching alone, healthy dietary advice alone, Variable regimens including Bryonia alba (Hahnemann Publishing Company) , Gelsemium sempervirens (Hahnemann Publishing Company) , ascorbic acid (Dusap Pharmaceuticals) , phosphorus (Hahnemann Publishing Company) Healthy volunteers accepted, Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) D.N. De Homoeopathic Medical College & Hospital, Ministry of Ayush India 2020-11-30 CTRI/2020/11/029265, U1111-1259-4250 Phase 3 Clinical Recruiting 1 20000 Prof Dr Satadal Das, Prof Dr Shyamal Kumar Mukherjee, Prof Dr Subhasish Ganguly 2020-11-25
ACE2-AVG: Angiotensin-converting Enzyme 2 (ACE2) Expression in Tonsils and Adenoids Coronavirus disease 19 infection, Tonsillitis adenoidectomy alone, tonsillectomy alone Assistance Publique Hopitaux de Paris France 2020-12-31 2021-09-30 ACE2-AVG, APHP201032, NCT04640610 Phase Not Applicable Not yet recruiting 9 9 Months 40 André Coste, MD, PhD, Benjamin Verillaud, MD, Bertrand Baujat, MD, PhD, Béatrix Barry, MD, PhD, Diane Evrard, MD, Emilie Bequignon, MD, Fiona Alvin, MD, Frédéric Tankere, MD, PhD, Hélène Morel, Jean-François Papon, MD, PhD, Philippe Herman, MD, PhD, Pierre Bonfils, MD, PhD, Pierre-Louis Tharaux, MD, PhD, Romain Luscan, MD, Sarah Atallah, MD, Vincent Couloigner, MD, PhD 2020-11-25
A phase II study of REVTx-99 for the treatment of early stage COVID‑19 patients at risk for hospitalization Coronavirus disease 19 infection REVTx-99 alone TLR-4 agonist Revelation Biosciences Phase 2 Clinical Planned 0 2020-11-24
An observation and comparison of the efficacy and relative satisfaction of health care workers while being monitored by the standard buddy technique versus the remote audio visual doffing surveillance (RADS) of the doffing process during the COVID-19 pandemic Coronavirus disease 19 infection remote audio visual surveillance technique alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Nehru HOSPITAL, Postgraduate Institute of Medical Education and Research India 2020-12-15 CTRI/2020/11/029233 Phase Not Applicable Not yet recruiting 1 200 Naveen Naik B 2020-11-24
An observational study for hospitalized patients with CAP, HAP and VAP Coronavirus disease 19 infection, Pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Nagoya University Hospital Japan 2020-11-24 UMIN000042522 Phase Not Applicable Recruiting 2 1500 Yuichiro Shindo 2020-11-25
Role Of Montelukast In Management Of COVID 19 Coronavirus disease 19 infection montelukast sodium alone, standard treatment alone Leukotriene D4 antagonist Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences Patna India 2020-11-25 CTRI/2020/11/029232 Phase 3 Clinical Not yet recruiting 1 90 DR VIJAY KUMAR 2020-11-25
The effect of the online child birth preparation classes on pregnant women during COVID-19 pandemic Anxiety disorder, Coronavirus disease 19 infection online child birth preparation educational session alone Female Tehran University of Medical Sciences Iran 2020-11-21 IR.TUMS.FNM.REC.1399.098, IRCT20190713044192N2 Phase Not Applicable Recruiting 1 100 Farnaz Farnam, Mohammadali Sahraeian 2020-11-26
A clinical trial of Siddha drugs M V kashayam (internally) for the management and treatment of COVID-19 Coronavirus disease 19 infection MV kashayam intake alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Arul Anandar College Madurai Herbal Market India 2020-11-25 CTRI/2020/11/029289 Phase 2/Phase 3 Clinical Not yet recruiting 1 130 Dr P Dharumarajan 2020-11-25
Impact of COVID-19 on screen time, physical activity, sleep pattern and food intake among students of 18 to 23 years Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs) Manipal Academy of Higher Education, Welcomgroup Graduate School of Hotel Administration India 2020-11-23 CTRI/2020/11/029235 Phase Not Applicable Not yet recruiting 1 478 Pallavi Mahesh Shettigar, Reshma Mariam Santhosh 2020-11-24
Group CBT for Intolerance of Uncertainty Coronavirus disease 19 infection, Generalized anxiety disorder Cognitive-behavioral treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Manitoba Canada 2020-11-30 2021-08-31 H2019:412, NCT04512378 Phase Not Applicable Not yet recruiting 1 9 Months 20 Elizabeth Hebert, PhD 2020-11-25
Psychotherapy Strategies for the Treatment of Professionals and Students From Essential Services With High Levels of Emotional Distress in the Context of COVID-19 Anxiety disorder, Coronavirus disease 19 infection, Depression Brief Interpersonal Telepsychotherapy alone, Cognitive Behavioral Brief-Telepsychotherapy alone Hospital de Clinicas de Porto Alegre Brazil 2020-11-05 2021-07-20 20200213_TREATMENT, NCT04635618 Phase Not Applicable Recruiting 1 8 Months 999 Giovanni Salum, MD, PhD 2020-11-25
ProneSpontCov: Awake Prone Position to Reduce Ventilation Inhomogeneity in COVID-19 Acute Respiratory Failure Coronavirus disease 19 infection, Respiratory failure Electrical impedance tomography (EIT) alone, lung ventilation in awake prone position alone, lung ventilation in dorsal decubitus alone, lung ventilation in ventral decubitus alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux De Marseille France 2020-04-04 2021-01-31 2020-17, NCT04632602, ProneSpontCov Phase Not Applicable Recruiting 1 9 Months 20 Christophe GUERVILLY, Jean-Olivier ARNAUD 2020-11-25
Evaluation of the Effects of L-carnitine Supplementation on Patients with COVID-19 Coronavirus disease 19 infection Variable regimens including L-carnitine (Karen Company) , dexamethasone , favipiravir , interferon-beta RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Hamadan University of Medical Sciences Iran 2020-11-20 IR.UMSHA.REC.1399.650, IRCT20200921048794N1 Phase 3 Clinical Recruiting 1 96 Dr Saman Talebi, Mehran Ghasemi, Rasool Haddadi, Saeed Bashirian 2020-11-25
A randomized, double-blind, placebo-controlled, phase III clinical trial of the effectiveness and safety of inoculation of recombinant new coronavirus vaccine (CHO cells) in the prevention of COVID-19 in people 18 years and older Coronavirus disease 19 infection ZF-2001 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hunan Province Centers for Disease Control and Prevention Pakistan, Ecuador, Uzbekistan, Indonesia, China 2020-11-06 2021-12-31 ChiCTR2000040153 Phase 3 Clinical Recruiting 5 13 Months 29000 Li Fangjun, Zhong Zaixin 2020-12-08
A Phase II clinical trial of novel coronavirus pneumonia (COVID-19) mRNA Vaccine (BNT-162b2) in China Coronavirus disease 19 infection, Viral pneumonia BNT-162b2 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry Jiangsu Province Centers for Disease Control and Prevention Shanghai Fosun Pharmaceutical Industry Development Co Ltd China 2020-11-23 2021-12-31 ChiCTR2000040044 Phase 2 Clinical Not yet recruiting 2 13 Months 960 Wang Wei, Zhu Fengcai 2020-12-02
A phase II, randomized, double-blind, placebo-controlled study to evaluate the safety and efficacy of leronlimab as a treatment for COVID-19 patients suffering from long-hauler symptoms Coronavirus disease 19 infection leronlimab alone CCR5 chemokine antagonist CytoDyn Inc US Phase 2 Clinical Planned 1 102 Dr Chris Recknor, Dr Kush Dhody, Dr Mahboob Rahman 2020-11-27
Pharmacokinetics, Safety, and Tolerability of CSL-760, an Anti-COVID-19 Hyperimmune Intravenous Immunoglobulin, in Healthy Adult Subjects Coronavirus disease 19 infection CSL-760 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) CSL Behring LLC 2020-12-31 2021-04-30 CSL760_1001, NCT04638634 Phase 1 Clinical Not yet recruiting 0 4 Months 24 Study Director, Trial Registration Coordinator 2020-11-25
Short- and Long-term Effects of Adding Oral L-arginine to Standard Therapy in Patients With COVID-19 (SARS-CoV-2) Coronavirus disease 19 infection, Viral pneumonia Bioarginina (L-arginine) alone, standard therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Campania Luigi Vanvitelli Italy 2020-11-18 2021-09-18 BIOARGININA, NCT04637906 Phase Not Applicable Not yet recruiting 1 10 Months 290 Giuseppe fiorentino 2020-11-25
A virtual global clinical trial to assess ePRO measures using Migraine Buddy mobile tracking app for an acute migraine medication in COVID-19 pandemic Coronavirus disease 19 infection, Migraine Migraine Buddy mobile tracking app alone Healint Pte Ltd 2020-11-18 COVID19_IMPACT Phase Not Applicable Recruiting 0 2020-11-23
Questionnaire Regarding the Effect of Wearing Face Masks on Oral Health Coronavirus disease 19 infection, Halitosis, Xerostomia face mask alone Healthy volunteers accepted University of Gottingen University Medical Center Goettingen Germany 2020-11-20 2021-07-01 FACEMASKS-ORALHEALTH, NCT04632004 Phase Not Applicable Recruiting 1 7 Months 3000 Philipp Kanzow, Dr. med. dent., Dr. rer. medic 2020-11-26
Effect of Home Exercise Activity on Cortisol and Depression in COPD During the Pandemic COVID Chronic obstructive pulmonary disease, Coronavirus disease 19 infection, Depression bicycle alone, moderate intensity home-exercise training alone, treadmill alone, upper and lower limb exercise alone Male, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Cairo University Egypt 2020-11-19 2021-03-01 NCT04639349, P.T.REC/012/002897 Phase Not Applicable Recruiting 1 3 Months 40 Ali Ismail, lecturer, Ali Mohamed Ali ismail 2020-11-26
Testing Scalable, Single-Session Interventions for Adolescent Depression in the Context of COVID-19 Coronavirus disease 19 infection, Depression behavioral activation SSI alone, growth mindset SSI alone Adolescents (13-17 yrs) State University of New York at Stony Brook University of Denver US 2020-11-19 2021-07-31 1505797-3, NCT04634903 Phase Not Applicable No longer recruiting 1 8 Months 2409 Jessica L Schleider, PhD 2020-12-09
COVID PLEX+CCP: Plasma Exchange (PLEX) and Convalescent Plasma (CCP) in COVID-19 Patients With Multiorgan Failure Coronavirus disease 19 infection, Hypoxia, Multiple organ failure centrifuge plasma exchange therapy alone, membrane plasma exchange therapy alone, standard care alone, Variable regimens including albumin , citrate , convalescent plasma , fresh frozen plasma , heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rigshospitalet Aalborg Hospital, Aarhus University Hospital, Odense University Hospital, Zealand University Hospital Denmark 2020-11-16 2022-06-30 COVID PLEX+CCP, H-20041716, NCT04634422 Phase 2 Clinical Not yet recruiting 1 19 Months 220 Anders Perner, Prof, Nicholas Carlson, MD, Wladimir M Szpirt, MD, Wladimir Szpirt 2020-11-25
A Synthetic MVA-based SARS-CoV-2 Vaccine, COH04S1, for the Prevention of COVID-19 Coronavirus disease 19 infection COH-04S1 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) City of Hope Medical Center National Cancer Institute US 2020-11-25 2022-11-10 20447, NCI-2020-08335, NCT04639466, P30CA033572 Phase 1 Clinical Recruiting 1 23 Months 129 John Zaia 2020-11-26
Targeting the Health Care Provider (HCP) Burnout Crisis During the COVID-19 Pandemic Acute stress disorder, Coronavirus disease 19 infection Transcendental meditation alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Duke University US 2020-11-30 2021-04-30 NCT04632368, PRO00106191 Phase Not Applicable Not yet recruiting 1 5 Months 80 Catherine Clinical Research Co-ordinator, Taylor Clinical Research Co-ordinator 2020-11-26
BRIDGE: Building Regulation in Dual Generations - Telehealth Model Coronavirus disease 19 infection, Depression BRIDGE therapy program alone, dialectical behavior therapy alone Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Manitoba Centre for Addiction and Mental Health, Research Manitoba, University of Oregon Canada 2020-09-01 2021-05-31 BRIDGE, BRIDGEV2.0, NCT04639557 Phase Not Applicable Recruiting 1 9 Months 40 2020-11-23
EUDOCO: Early Versus Delayed Intubation of Patients With COVID-19 Coronavirus disease 19 infection, Hypoxia, Respiratory failure endotracheal intubation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Evangelismos Hospital Greece 2020-11-18 2021-05-01 32635, 13-10-2020, EUDOCO, NCT04632043 Phase Not Applicable Not yet recruiting 1 5 Months 80 Ilias Siempos, MD, DSc 2020-11-26
Patient Centered Intervention to Prevent Tuberculosis Among Children < 5 Years Old Coronavirus disease 19 infection, Mycobacterium tuberculosis infection educational booklet alone, isoniazid alone, isoniazid preventive therapy alone, weekly SMS alone, weekly children storybook session alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidad Peruana Cayetano Heredia Peru 2019-12-01 2023-12-15 103161, NCT03881228 Phase 2 Clinical Recruiting 1 48 Months 300 Larissa Otero, MD PhD, Larissa Otero, PhD 2020-11-26
Telepsychoeducation for the Prevention of Emotional Distress in Professionals and Students From Essential Services in the Context of COVID-19 Acute stress disorder, Coronavirus disease 19 infection telepsychoeducation with personalized videos alone Hospital de Clinicas de Porto Alegre Brazil 2020-11-05 2021-07-20 20200213_PREVENTION, NCT04632082 Phase Not Applicable Recruiting 1 8 Months 2200 Giovanni Salum, MD, PhD 2020-11-23
The Effect of Ganglion Sphenopalatine Block (SPG-block) Versus Placebo on Persistent Headache Following Acute COVID-19 Infection Coronavirus disease 19 infection, Headache ganglion sphenopalatine block (SPG block) alone, lidocaine plus ropivacaine Sodium channel inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Bispebjerg and Frederiksberg Denmark 2020-12-31 2021-11-30 GSPB-COVID-2020, NCT04636034 Phase 3 Clinical Not yet recruiting 1 11 Months 60 Christian S Meyhoff, PhD, Mads S Jespersen, MD, Mads Seit Jespersen 2020-11-24
COVID_CRC: The Impact of Covid-19 Pandemic on Colorectal Cancer Prevention Due to Delays in Diagnosis: a Global Study Colorectal tumor, Coronavirus disease 19 infection Colonoscopy alone Istituto Clinico Humanitas Italy 2020-12-16 2021-03-31 100, COVID_CRC, NCT04637893 Phase Not Applicable Not yet recruiting 1 3 Months 1000 Alessandro Repici, MD, Roberta Maselli, MD 2020-11-24
Online Trial of Meditation and Behavior Coronavirus disease 19 infection Loving-Kindness Meditation training alone, Relaxation Meditation training alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Georgetown University US 2020-11-20 2021-11-20 2010-180-2, NCT04632875 Phase Not Applicable Recruiting 1 12 Months 68 Abigail A Marsh, PhD, Study Coordinator 2020-11-23
NeuroCovid Rehab and Recovery Related to COVID-19 Diagnosis Coronavirus disease 19 infection, Neurological disease Soterix taVNS model 0125-LTE stimulator alone, transcutaneous auricular vagus nerve stimulation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Medical University of South Carolina National Institute of General Medical Sciences, National Institutes of Health US 2020-11-19 2021-06-30 00101270, NCT04638673, U54GM104941-08 Phase 2 Clinical Recruiting 2 7 Months 30 Mark S George, MD, Morgan Dancy, BA, Sarah Huffman, BA 2020-12-08
Prayer in Commbate to Corona Virus - COVID-19 Coronavirus disease 19 infection prayers by theologians alone, protcol treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital do Coracao Brazil 2020-08-01 2021-01-31 NCT04631380, PRAYER-COVID19 Phase Not Applicable Recruiting 1 6 Months 200 Alexandre B Cavalcanti, MD, PhD, NATHAN V SOUBIHE JR, sabrina bernardez 2020-11-24
Video Home Visits for Dietary Counselling Coronavirus disease 19 infection, Urolithiasis urologist and dietitian virtual home visits alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of California San Francisco US 2021-01-01 2024-07-01 NCT04634851, UCSFUROVV Phase Not Applicable Not yet recruiting 1 42 Months 100 David Bayne, MD, MPH, Marshall Stoller, MD 2020-11-24
UNITED: At-Home Infusion Using Bamlanivimab in Participants With Mild to Moderate COVID-19 Coronavirus disease 19 infection bamlanivimab alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Aged Adults (65-79 yrs), Elderly Adults (80 and over) UnitedHealth Group Inc Eli Lilly & Co, Optum Inc 2020-11-30 2021-05-31 2020-0081, NCT04639479, UNITED Phase 4 Clinical Not yet recruiting 0 6 Months 7500 Dan Griffin, MD PHD, Michelle Tanner, BA, Tracy Ziolek, MS 2020-12-07
Co-VIS: Benefits of Using a Transparent Visor to Replace the Face Mask in Speech Therapy Rehabilitation of Oral-Linguo-Facial Praxies in the Context of COVID-19: a Series of Cases Apraxia, Coronavirus disease 19 infection speech therapy rehabilitation alone, transparent covering visor alone, video sequence watching alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-11-30 2021-02-28 APHP200876, Co-VIS, IDRCB, NCT04639427 Phase Not Applicable Not yet recruiting 1 3 Months 4 Julie PAQUEREAU, MD 2020-11-25
NOSO-COR IMMUNO: COVID-19 - Multicenter Study on Nosocomial Transmission of SARS-CoV-2 Virus: an Ancillary Study Coronavirus disease 19 infection blood sampling alone, nasopharyngeal sampling alone, salivary sampling alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospices Civils De Lyon France 2020-11-23 2021-11-01 69HCL20_0761, NCT04637867, NOSO-COR IMMUNO Phase Not Applicable Not yet recruiting 1 11 Months 200 MITRA ELAHI, PhD, Philippe VANHEMS, MD 2020-11-25
REHABCOVID: Organization of Pulmonary Rehabilitation of Post-COVID-19 Patient With Sequela Anxiety disorder, Coronavirus disease 19 infection, Depression, Dyspnea, Fatigue, Respiratory disease aerobic exercise alone, ergocycle alone, heart rate monitor alone, medical consultation alone, muscle strengthening exercise alone, occupational therapy alone, psychomotricity alone, respiratory tele-rehabilitation program alone, sophrology alone, walking exercise alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer France 2020-11-30 2022-01-31 2020-A02838-31, 2020-CHITS-06, NCT04634318, REHABCOVID Phase Not Applicable Not yet recruiting 2 14 Months 118 Asmaa Jobic, Charles Simon, MD, Jean-Marc Vallier, MD, Nicolas Paleiron, MD 2020-11-28
Online Multi-component Psychological Intervention for Prevention of Grief Disorder Due to COVID-19 Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder, Sleep disorder Multi-component psychological online intervention alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Universidad Internacional de Valencia Universidad Autonoma de Ciudad Juarez, Universidad Nacional Autonoma De Mexico, University of Buenos Aires Mexico 2020-12-15 2021-06-01 NCT04638842, VIU-GRIEF-COVID Phase Not Applicable Not yet recruiting 1 5 Months 42 Alejandro Dominguez Rodriguez, PhD, Anabel de la Rosa, Gómez, Carlos Armando Arzola, MD, Esteban Eugenio Esquivel Santoveña, PhD, Flor Rocío Ramírez Martínez, PhD, Luis Farfallini, PhD, María Jesús Hernández Jimenez, PhD, Paulina Arenas Landgrave, PhD, Rosa Olimpia Castellanos Vargas, MD, Sofía Cristina Martínez Luna, MD 2020-11-25
An observational, retrospective, propensity-matched study to evaluate the impact of famotidine use on clinical outcomes of hospitalized patients with COVID-19 Coronavirus disease 19 infection famotidine alone Histamine H2 receptor antagonist Hartford Hospital US Phase Not Applicable Status not specified 1 878 2020-11-23
CureCovid-2019: A Study to Compare the Efficacy of GNS-561 Versus Standard of Care in Patients With SARS-CoV-2 (COVID-19) Infection Coronavirus disease 19 infection GNS-561 alone, standard of care alone Autophagy protein inhibitor, Solute carrier family inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Genoscience France 2020-11-18 2021-10-30 CureCovid-2019, GNS561-CL-I-Q-0291, NCT04637828 Phase 2 Clinical Recruiting 1 11 Months 178 Christelle Ansaldi, Christelle Ansaldi, MD 2020-11-25
Polio Vaccine (IPV) for SARS-CoV-2 and Prevention of Coronavirus Disease (COVID-19) Coronavirus disease 19 infection polio vaccine, Sanofi Pasteur alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) E-MO Biology Inc US 2020-11-15 2021-01-15 EMO-001, NCT04639375 Phase 4 Clinical Recruiting 2 2 Months 25 Brittany Comunale, John Andrews, John Andrews, PhD 2020-12-10
COVIFAT: Impact of Adipose Tissue in COVID-19 Coronavirus disease 19 infection, Inflammatory disease, Obesity adipose tissue sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-11-23 2021-11-23 2020-A02403-36, APHP200983, COVIFAT, NCT04639440 Phase Not Applicable Not yet recruiting 1 12 Months 60 Fabienne FOUFELLE, Dr, Olivier BOURRON, Dr 2020-12-02
A phase III trial of AMY-101 for the treatment of severe COVID-19 patients Coronavirus disease 19 infection AMY-101 alone Complement C3 inhibitor University of Pennsylvania Brazil Phase 3 Clinical Planned 1 2020-11-23
The effect of massage training on the resilience of pregnant women Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression telemedicine-based massage training alone Female, Young Adults (18-44 yrs) Islamic Azad University Iran 2020-11-04 IR.IAU.MSHD.REC.1399.159, IRCT20170607034378N2 Phase Not Applicable Recruiting 2 120 Ali Asghar Mahmudi, Dr Saeed Khayat Moghadam, Fatemeh Jalal Marvi, Mahdi Sayad Kame Olya 2020-11-24
The role of hemoperfusion in COVID-19 Coronavirus disease 19 infection, Respiratory failure Standard of care treatment alone, hemoperfusion alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shaheed Beheshti Medical University Iran 2020-10-17 IR.SBMU.RETECH.REC.1399.582, IRCT20200608047686N2 Phase 2 Clinical Recruiting 1 40 Afshin Zarghi, Muhanna Kazempour 2020-11-24
COVID-19 pandemic effects on depression, anxiety and help-seeking attitudes in college students Anxiety disorder, Coronavirus disease 19 infection, Depression SurveyMonkey platform alone Healthy volunteers accepted University of Porto Portugal 2019-02-01 2021-06-01 ISRCTN63459073, PMHDS-1 Phase Not Applicable No longer recruiting 1 28 Months 500 Mrs Virginia Conceicao 2020-11-25
Qualitative Study: Issues Faced by Female Staffs During the Pandemic COVID-19 Coronavirus disease 19 infection Hospital Tuanku Fauziah Malaysia 2020-11-23 2021-04-30 57017, NMRR-20-2507-57017 Phase Not Applicable Not yet recruiting 1 5 Months Dr Noor Melissa Binti Nor Hadi 2020-11-23
TECOVID: Thrombotic Complications Among COVID-19 Patients: A Multicenter Study from a Malaysian Perspective Coronavirus disease 19 infection, Phlebothrombosis Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universiti Teknologi Mara Malaysia 2020-12-01 2021-11-30 56439, NMRR-20-2465-56439, TECOVID Phase Not Applicable Status not specified 2 12 Months 3035 Dr Hanis Hanum Zulkifly, Dr Lee Chew Kiok, Dr Leong Chee Loon 2020-11-24
Cross-Sectional Study: Factors Contributing to Burnout Among Healthcare Workers in Sabah Coronavirus disease 19 infection, Psychiatric disorder Healthy volunteers accepted Hospital Tuanku Fauziah Malaysia 2020-12-01 2021-04-30 57139, NMRR-20-2494-57139 Phase Not Applicable Not yet recruiting 3 5 Months Dr Noor Melissa Binti Nor Hadi 2020-11-26
Management of Depression and Anxiety in HF Anxiety disorder, Cardiac failure, Coronavirus disease 19 infection, Depression web-based COMPASS intervention alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) King's College London UK 2020-10-02 2021-08-16 IRAS ID: 268951, NCT04636944 Phase Not Applicable Recruiting 1 10 Months 13 Annmarie Grealish, Catherine Evans, Sameera Helal, Silapiya Smith 2020-11-24
An observational, retrospective, cohort study to investigate the potential hepatotoxicity of lopinavir/ritonavir in severely ill patients for the treatment of COVID-19 infection Coronavirus disease 19 infection, Hepatotoxicity drug-induced lopinavir + ritonavir alone HIV protease inhibitor Centre Hospitalier Regional Universitaire de Lille Phase Not Applicable Status not specified 0 42 2020-11-24
Short Term Effects in Pulmonary Function Among COVID-19 Recovered Adult Patients in a Tertiary Hospital in Davao City Coronavirus disease 19 infection, Dyspnea Southern Philippines Medical Center Philippines 2021-01-18 2021-04-18 PHRR201110-003113 Phase Not Applicable Not yet recruiting 1 3 Months Benjo P. Ato, Christoper John Q. Quadra 2020-11-23
COVID-CMR: Prevalence of Myocardial Scars on CMR After COVID-19 Infection Coronavirus disease 19 infection, Myocardial disease Cardiac Magnetic Resonance Imaging alone, ECG monitoring alone, treadmill exercise test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Bordeaux Universite de Bordeaux France 2020-06-13 2021-04-13 CHUBX 2020/22, COVID-CMR, NCT04636320 Phase Not Applicable Recruiting 1 10 Months 240 Hubert COCHET, MD-PhD, Nathalie COTTIGNIES, Pierre JAïS, MD-PhD 2020-11-23
Phase I Trial of a Recombinant COVID-19 Vaccine (CHO Cell) Coronavirus disease 19 infection SARS-CoV-2 vaccine (CHO Cell) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry Jiangsu Province Centers for Disease Control and Prevention Chinese Academy of Medical Military Sciences, Liaoning Maokangyuan, Zhongyi Anke Biotechology Co Ltd China 2020-10-30 2022-01-07 JSVCT096, NCT04636333 Phase 1 Clinical Recruiting 1 14 Months 216 Fanyue Meng, Doctor, Fengcai Zhu, Doctor, Mingwei Wei 2020-12-02
Effect of Vitamin D on Hospitalized Adults With COVID-19 Infection Coronavirus disease 19 infection cholecalciferol alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Liege Laboratoires SMB SA Belgium 2020-11-12 2021-02-28 D-COVID, NCT04636086 Phase 4 Clinical Recruiting 1 3 Months 100 Anne-Françoise Rousseau, Anne-Françoise Rousseau, MD, PhD 2020-11-23
A retrospective, cohort study on safety, tolerability, and clinical outcomes of hydroxychloroquine for hospitalized patients with coronavirus 2019 disease Coronavirus disease 19 infection hydroxychloroquine alone National Center For Advancing Translational Sciences, National Institutes of Health, US Department of Health and Human Services US Phase Not Applicable Status not specified 1 153 2020-12-08
PEACE: Perceptions, Experiences, and Activity in Cancer Survivors During COVID-19 Cancer, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Nebraska US 2020-12-01 2021-06-30 768-20, NCT04637295, PEACE Phase Not Applicable Not yet recruiting 1 7 Months 1000 Diane K Ehlers, PhD, Lindsey Page, MS, Nicholas J Foggia, MS 2020-11-23
A clinical trial of light activated photodynamic compound vaccine (COVID-19 infection), Theralase Technologies/University of Manitoba for the potential treatment of COVID-19 infection Coronavirus disease 19 infection light activated photodynamic compound vaccine (COVID-19 infection), Theralase Technologies/University of Manitoba alone Theralase Technologies Inc Phase Not Applicable Planned 0 2020-11-23
Methylene Blue Treatment of COVID-19 Coronavirus disease 19 infection methylene blue alone, standard therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Epatocentro Ticino Foundation Switzerland 2020-11-30 2022-12-31 MB TREATMENT OF COVID19, NCT04635605 Phase 2 Clinical Not yet recruiting 1 25 Months 64 Andreas Cerny, Prof, Maurizia Bissig 2020-11-24
MEDEAS: Methylprednisolone Versus Dexamethasone in COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia methylprednisolone alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) L'Universita Degli Studi di Trieste Centro Di Riferimento Oncologico (CRO Aviano), Istituto Nazionale Per Le Malattie Infettive "Lazzaro Spallanzani" Italy 2020-11-25 2021-04-30 MEDEAS, MEDEAS1, NCT04636671 Phase 3 Clinical Not yet recruiting 1 5 Months 680 Francesco Salton, MD, Marco Confalonieri, MD 2020-11-24
KORANIT: Serological Diagnostics of COVID-19 in Health Care Workers Coronavirus disease 19 infection blood test alone, nasal swab test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University Medical Centre Ljubljana Slovenia 2020-11-30 2021-01-31 KOAIT-1-2020, KORANIT, NCT04635592 Phase Not Applicable Not yet recruiting 1 2 Months 300 Marko Zlicar, MD, PhD, Peter Poredos, Assist. prof, Peter Poredos, MD, PhD 2020-11-27
An observational comparative study on the effects of second week methylprednisolone pulses in patients with severe coronavirus disease 2019 pneumonia Coronavirus disease 19 infection, Pneumonia methylprednisolone alone Hospital de Cruces Spain Phase Not Applicable Status not specified 1 242 2020-11-23
Study of a Recombinant Coronavirus-Like Particle COVID-19 Vaccine in Adults Coronavirus disease 19 infection MT-2766 alone TLR-9 agonist Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Medicago Inc GlaxoSmithKline plc US, North America, Canada, Europe 2020-11-19 2022-04-30 CP-PRO-COVLP-021, NCT04636697 Phase 2/Phase 3 Clinical Recruiting 6 17 Months 30612 Andre Frechette, Brian Ward, MD, Guy Tellier, Jean-Sebastien Gauthier, Jean-Sebastien Paquette, Mary Hardison 2020-12-01
Personalized Phage Treatment in COVID-19 Patients With Bacterial Co-Infections Microbials for Pneumonia or Bacteremia/Septicemia Acinetobacter baumannii infection, Bacterial infection, Coronavirus disease 19 infection, Pseudomonas aeruginosa infection, Sepsis, Staphylococcus aureus infection, Viral pneumonia Phage Therapy alone, anti-microbial therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Adaptive Phage Therapeutics Inc APT.APS.001, NCT04636554 Phase Not Applicable Recruiting 0 Robert J Hopkins, MD, MPH&TM, FACP, FIDSA, Stephanie Holland 2020-11-24
Burden of COVID-19 Infection in Populations With High or Low Risk of Infection Coronavirus disease 19 infection, Post traumatic stress disorder app alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Neuromed IRCCS Italy 2020-12-15 2022-06-15 DEP_032020, NCT04636203 Phase Not Applicable Not yet recruiting 1 18 Months 3500 Chiara Cerletti, MS, Licia Iacoviello, MD, PhD 2020-11-24
A large clinical diagnostic study to assess COVID-19 in exhaled breath condensate (EBC) using CoronaCheck diagnostic test Coronavirus disease 19 infection CoronaCheck diagnostic test alone Exhalation Technology Limited UK 2020-11-02 Phase Not Applicable Recruiting 1 300 Anoop Chauhan 2020-11-25
Immune Profiling with Antibody-based COVID-19 Testing Coronavirus disease 19 infection, Multiple myeloma Antibody-based COVID-19 Testing alone African Ancestry Quest Diagnostics Inc Dana-Farber Cancer Institute Inc US Phase Not Applicable Status not specified 1 1000 Irene Ghobrial, MD 2020-11-20
Vital Sensor Monitors for CV19 Detection Coronavirus disease 19 infection ANNE One wireless vital sign monitoring device alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Northwestern University US Department of Defense US 2020-11-05 2022-10-30 NCT04635787, STU00213040 Phase Not Applicable Recruiting 1 23 Months 300 Shuai (Steve) Xu 2020-11-23
An observational, retrospective, US cohort study to evaluate the COVID-19 disease severity in patients with multiple sclerosis (MS) treated with ocrelizumab Coronavirus disease 19 infection, Multiple sclerosis ocrelizumab alone B-lymphocyte antigen CD20 inhibitor Roche Holding AG US Phase 4 Clinical Status not specified 0 357 2020-12-09
RECIPE: Restoring Non-Emergent Cardiovascular Care in the Peri- COVID-19 Era Coronavirus disease 19 infection cardiac procedures alone Healthy volunteers accepted Pinnacle Health US 2020-08-01 2022-06-30 NCT04636021, RECIPE, UPMCP- 20-007 Phase Not Applicable Recruiting 1 23 Months 1000 William Bachinsky MD, William Bachinsky, MD 2020-11-23
INHALE-HEP: Inhaled Heparin for Hospitalized COVID-19 Patients Coronavirus disease 19 infection standard care alone, unfractionated heparin alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The Australian National University Helwan University Argentina, Egypt 2020-06-01 2021-06-01 INHALE-HEP, INHALE-HEP META-TRIAL, NCT04635241 Phase 2/Phase 3 Clinical Recruiting 2 12 Months 656 Alicia B Vilaseca, PhD, Frank MP van Haren, MD, PhD, Frank van Haren, Tarek I Ismail 2020-11-24
H2Covid: Hydrogen Therapy in Patients With Moderate Covid-19 Coronavirus disease 19 infection conventional oxygen therapy alone, hydrogen therapy alone, nasal cannula alone, Variable regimens including hydrogen , nitrogen , oxygen Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Grenoble France 2020-12-01 2021-09-30 38RC20.277, H2Covid, NCT04633980 Phase 1 Clinical Not yet recruiting 1 10 Months 10 BOUCHER François, PhD, Jean Paul Brion, MD, Saber TOUATI, PhD 2020-11-23
Impact of Social Distancing on Bariatric Versus Non-Surgical Obese Patients During COVID-19 Pandemic Coronavirus disease 19 infection, Obesity bariatric surgery alone, medical weight management alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Singapore General Hospital Pte Ltd Singapore 2020-06-01 2020-07-30 HENRYLEW, NCT04633941 Phase Not Applicable Completed 1 1 Month 272 Chin Hong Lim, FRCS 2020-11-27
Borderline COVID-19 PCR Test Result Coronavirus disease 19 infection PCR test alone Jessa Hospital Belgium 2020-08-01 2020-12-30 F/2020/166, NCT04636294 Phase Not Applicable No longer recruiting 1 4 Months 30000 2020-11-23
The Impact of COVID-19 Pandemic on Thyroid Surgery in Italy: Results From a Nation-wide, Multicentric Study Coronavirus disease 19 infection, Thyroid disease Thyroidectomy alone University of Cagliari Italy 2020-03-10 2020-11-12 NCT04635813, THYCOVIT Phase Not Applicable Completed 1 8 Months 3800 Fabio Medas 2020-11-23
PallPan AP 4: COVID-19: National strategy for palliative care during times of a pandemic - generalst palliative care in hospitals Coronavirus disease 19 infection focus group interview alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitätklinikum Düsseldorf Bundesministerium für Bildung und Forschung Germany 2020-12-01 2020-1119, DRKS00023595, PallPan AP 4 Phase Not Applicable Not yet recruiting 1 30 Martin Neukirchen 2020-11-23
A phase I clinical trial of TNX-1800 for the potential prevention of COVID-19 infection Coronavirus disease 19 infection TNX-1800 alone COVID19 Spike glycoprotein modulator Tonix Pharmaceuticals Holding Corp Phase 1 Clinical Planned 0 2020-11-20
A phase III trial of PegiHep for the treatment of COVID-19 Coronavirus disease 19 infection peginterferon alfa-2b follow-on-biologic, Zydus-Cadila alone Interferon alpha 2 ligand Zydus-Cadila Group India Phase 3 Clinical Planned 1 250 2020-12-09
Effect of Ivermectin in treatment of COVID-19 Coronavirus disease 19 infection Variable regimens including Lopinavir/Ritonavir , hydroxychloroquine sulfate , interferon beta-1a follow-on biologic (intramuscular), CinnaGen , ivermectin Chloride channel modulator, Interferon beta ligand Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bandare-abbas University of Medical Sciences Iran 2020-11-15 IR.HUMS.REC.1399.410, IRCT20200506047323N6 Phase 3 Clinical Recruiting 1 120 Mahdi Hasani Azad, Mohammad Fathalipour 2020-11-26
Phase I Clinical Trial on NK Cells for COVID-19 Coronavirus disease 19 infection natural killer cells alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital de Clinicas de Porto Alegre Brazil 2021-01-02 2021-03-30 20200210, NCT04634370 Phase 1 Clinical Not yet recruiting 1 2 Months 24 Annelise Pezzi, PhD, Lucia Silla, MD, PhD, Lucia Silla, Md, PhD 2020-11-23
COV-HD: Antibody Response in Hemodialysis and Non-dialysis Patients Diagnosed With COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Saint Petersburg State University Russian Federation 2020-11-30 2021-08-31 COV-HD, COVID, NCT04633915 Phase Not Applicable Not yet recruiting 1 9 Months 40 Ekaterina Parshina 2020-11-23
An observational study on the factors associated with prolonged viral shedding and impact of lopinavir/ritonavir treatment in hospitalized non-critically ill patients with SARS-CoV-2 infection Coronavirus disease 19 infection lopinavir + ritonavir alone HIV protease inhibitor Zhengzhou University China Phase Not Applicable Status not specified 1 120 2020-11-19
Ezrin Peptide (HEP-1) for Treatment of Coronavirus Disease (COVID-19) Infection Coronavirus disease 19 infection Gepon alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Shaheed Beheshti Medical University praxisgemeinschaft für zelltherapie Iran 2020-12-20 2021-04-01 IR.SBMU.REC.1399.023, NCT04627233 Phase 1 Clinical Not yet recruiting 1 3 Months 20 Farzad Ashrafi 2020-11-23
A Study Evaluating the Efficacy and Safety of CKD-314 in Hospitalized Adult Patients Diagnosed With COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia nafamostat (COVID-19 infection), Institut Pasteur Korea alone, standard of care alone Serine protease inhibitor, Transmembrane serine protease 2 inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chong Kun Dang Pharmaceutical Corp South Korea 2020-11-20 2021-06-30 A108_01CVD2013, NCT04628143 Phase 2 Clinical Not yet recruiting 1 7 Months 100 Dongho Kim, MD 2020-11-24
The Severity of COVID-19 in Diabetes and Non-diabetes Patients (COVID-19) Coronavirus disease 19 infection, Non-insulin dependent diabetes Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry Dr. A. Ramachandran's Diabetes Hospitals, India Diabetes Research Foundation India 2020-11-16 2021-05-16 CTRI/2020/12/029454, IDRFARH015, IDRFARH015 Version 2.0, NCT04634214 Phase Not Applicable Not yet recruiting 4 6 Months 1050 Ambady Ramachandran, M.D,PhD,DSc, Dr A Subair Khan, Dr Ambady Ramachandran, Dr Sruti Chandrasekaran, Dr Su Thillai Vallal, Dr T Palaniappan, Palaniappan T, M.D, Sruti Chandrasekaran, M.D.,D.M, Su Thillai Vallal, M.D, Subair Khan, M.S 2020-12-02
STOP Severe COVID-19: Study To antagonize Plasminogen Activator Inhibitor-1 in Severe COVID-19 Coronavirus disease 19 infection TM-5614 alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Northwestern University US 2020-11-16 2022-06-30 NCT04634799, STOP Severe COVID-19, STU00213262 Phase 1/Phase 2 Clinical Recruiting 1 19 Months 80 Anna Huskin, RN, Douglas E Vaughan, MD, Lyndsay Christensen, MSN, Sanjiv J Shah, MD, Sanjiv Shah, MD 2020-11-23
MP-COVID: The MentalPlus for Assessment and Rehabilitation of Cognitive Function After Remission of the Symptoms of COVID-19 Cognitive disorder, Coronavirus disease 19 infection MentalPlus digital game alone Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Sao Paulo Brazil 2020-11-08 2023-12-29 MENTALPLUS, MP-COVID, NCT04632719 Phase Not Applicable Recruiting 1 37 Months 200 Julia S Valentin, Fellow, Julia S. Valentin, Fellow, Julia SS Valentin, Bacharel, Livia S. Valentin, Ph.D, Livia S. Valentin, Ph.D., Livia SS Valentin, Ph.D, Livia Stocco S Valentin, Ph.D, Luiz Antonio M Cesar, Ph.D, Luiz Aparecido Bortolotto, Ph.D 2020-11-25
EpiSARS2: Prevalence and Risk Factors of COVID-19 in the Upper Silesian Agglomeration Coronavirus disease 19 infection Healthy volunteers accepted Slaski Uniwersytet Medyczny w Katowicach Poland 2020-06-22 2021-04-22 2020/ABM /COVID19/0044, EpiSARS2, NCT04627623 Phase Not Applicable Recruiting 1 10 Months 6000 Grzegorz M Brozek, Prof, Jan E Zejda, Prof, Prof. Grzegorz Brożek,, Rafał Trela 2020-11-23
Assessment of Stress, Depression and Anxiety in Healthcare Caring for Patients With COVID-19 Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression, Sleep disorder Beck's Test alone, COPE test alone, Test PSS alone, Test STAI alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Jagiellonian University Poland 2020-07-01 2021-12-31 1072.6120.161.2020, NCT04631497 Phase Not Applicable Recruiting 1 18 Months 100 Tomasz Skladzien, Ph.D. M.D, Tomasz Skladzien, Ph.D. M.D., Tomasz Skladzien, PhD 2020-11-23
Exploratory Phase I Trial of the Active IMP in Healthy Volunteers in Relation to COVID-19 Coronavirus disease 19 infection ivermectin (extended release/sc/BEPO, COVID-19), MedinCell alone Healthy volunteers accepted, Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) MedinCell SA MAC Clinical Research UK 2020-09-22 2021-05-31 MDC-TTG-CT-001, NCT04632706 Phase 1 Clinical Recruiting 1 8 Months 24 Chief Development Officer, Joel Richard, L Cheung, P M Leung, R Kelshaw 2020-11-24
An European clinical study to assess RLF-100 in the treatment of patients with COVID-19 induced lung injury Coronavirus disease 19 infection, Lung injury aviptadil (inhaled, sarcoidosis/acute lung injury/acute respiratory distress syndrome associated COVID-19), Relief Therapeutics Holding alone Adrenergic receptor antagonist, VIP receptor agonist Relief Therapeutics Holding AG Syneos Health Inc Europe 2021-03-31 Phase Not Applicable Planned 0 2020-11-19
MEDIC-LAUMC: Managing Endothelial Dysfunction in COVID-19: A Randomized, Controlled Trial at LAUMC Coronavirus disease 19 infection, Dyspnea, Respiratory distress syndrome, Vascular disease anticoagulation therapy alone, Variable regimens including L-arginine , atorvastatin , dexamethasone , folic acid , nebivolol , nicorandil , vitamin C , zinc Beta 1 adrenoceptor antagonist, Beta 3 adrenoceptor agonist, HMG CoA reductase inhibitor, Potassium channel stimulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) LAU Medical Center Lebanon 2020-11-10 2021-05-01 LEBANESE AMERICAN UNIVERSITY, MEDIC-LAUMC, NCT04631536 Phase 0 Clinical Not yet recruiting 1 5 Months 80 Kamal Matli, Matli Kamal, MD 2020-11-23
A phase IIb, confirmatory study of Zofin in the treatment of patients with COVID-19 infection Coronavirus disease 19 infection Zofin alone Organicell Regenerative Medicine 2021-03-31 Phase 2b Clinical Planned 0 2020-11-19
IvermecPrev-Brazil: Study on the effects of using ivermectin to prevent COVID-19 in an adult population in Brazil Coronavirus disease 19 infection ivermectin alone Chloride channel modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidade Federal de Pernambuco University of Toronto Brazil 2020-04-10 2021-06-30 ISRCTN90437126, IVERMECPREV-BRAZIL SCINETN001.2020, IvermecPrev-Brazil Phase 3 Clinical Recruiting 1 14 Months 800 Prof Denia Fittipaldi-Duarte, Prof deCastro 2020-11-24
EAVE II: Early Pandemic Evaluation and Enhanced Surveillance of the coronavirus COVID-19 Coronavirus disease 19 infection vaccine programmes alone Academic and Clinical Centre Office for Research and Development [ACCORD], UK UK 2020-03-01 2021-09-30 EAVE II, IRAS 114474, ISRCTN40292537 Phase Not Applicable Recruiting 2 19 Months 5400000 Prof Sheikh 2020-11-25
Cash transfers to stimulate school re-enrollment among vulnerable adolescent girls in urban informal settlements as Kenya responds to COVID-19 Coronavirus disease 19 infection one-time cash transfer alone Healthy volunteers accepted, Female Population Council - Kenya Bill & Melinda Gates Foundation, Department for International Development, Echidna Giving Kenya 2020-10-02 2021-06-30 ISRCTN12792822, P661 Phase Not Applicable Not yet recruiting 1 8 Months 1700 Dr Austrian 2020-11-25
DZIF-10c_Inhalation: COVID-19 - Administration of the SARS-CoV-2-Neutralizing Monoclonal Antibody DZIF-10c (Inhalation) Coronavirus disease 19 infection DZIF-10c (iv, COVID-19), University of Cologne/Boehringer Ingelheim alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Cologne Boehringer Ingelheim International GmbH, The Clinical Trials Centre Cologne Germany 2020-11-23 2021-06-30 DZIF-10c_Inhalation, NCT04631705, UNI-KOELN-4370 Phase 1/Phase 2 Clinical Recruiting 1 7 Months 69 Florian Klein, Univ.Prof., Gerd Fätkenheuer, Henning Gruell, Dr. med. 2020-12-09
APEL-COVID: Apelin; ACE2 and Biomarkers of Alveolar-capillary Permeability in SARS-cov-2 (COVID-19) Adult respiratory distress syndrome, Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universite de Sherbrooke University Hospital, Angers Canada 2020-10-26 2021-12-01 2021-3862-APEL-COVID, APEL-COVID, NCT04632732 Phase Not Applicable Recruiting 1 13 Months 140 Frédéric Chagnon, MSc, Olivier Lesur, MD PhD 2020-11-23
An observational study to evaluate the pharmacokinetics and safety of lopinavir in COVID-19 patients Coronavirus disease 19 infection, SARS coronavirus infection lopinavir + ritonavir alone HIV protease inhibitor CHU De Nantes France Phase Not Applicable Status not specified 1 12 2020-11-19
Physical Activity and the Risk of COVID-19 Infection and Mortality Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry Wonju Christian Hospital South Korea 2014-01-01 2020-07-31 2020AN0292, NCT04631861 Phase Not Applicable Completed 1 79 Months 132069 Dong-Hyuk Cho 2020-11-23
A retrospective, single-center, case-control, comparative analysis on the safety and efficacy of anti-IL6 tocilizumab in patients with COVID-19 Coronavirus disease 19 infection tocilizumab alone Osped Niguarda Ca Granda Phase Not Applicable Status not specified 0 222 2020-11-19
Sleep and Covid19: Sleep Behavior in Athletes During Home Confinement Due to the Covid-19 Outbreak Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs) Istituto Ortopedico Galeazzi Spa Italy 2020-05-22 2021-02-28 NCT04632615, SLEEP&COVID19, Sleep and Covid19 Phase Not Applicable Recruiting 1 9 Months 230 Jacopo Antonino Vitale, PhD, Stefano Borghi, MSc 2020-11-19
PROPEL: Intravenous Zotatifin in Adults With Mild or Moderate COVID-19 Coronavirus disease 19 infection zotatifin alone Eukaryotic initiation factor 4A-I inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of California San Francisco, eFFECTOR Therapeutics Inc Medpace Inc 2020-11-16 2021-07-01 EFT226-0003, NCT04632381, PROPEL Phase 1b Clinical Not yet recruiting 0 7 Months 36 Mark Densel, Neil Sankar, MD, MPH, Rhonda Petsch 2020-11-24
COVID-19 - Administration of the SARS-CoV-2-Neutralizing Monoclonal Antibody DZIF-10c (Infusion) Coronavirus disease 19 infection DZIF-10c alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Cologne Boehringer Ingelheim International GmbH Germany 2020-11-23 2021-06-30 NCT04631666, UNI-KOELN-4288 Phase 1/Phase 2 Clinical Not yet recruiting 1 7 Months 69 Florian Klein, Univ.Prof., Gerd Faetkenheuer, Univ.-Prof., Gerd Fätkenheuer, Henning Gruell, Dr. med. 2020-11-30
A Phase II Clinical Trial of Recombinant Corona Virus Disease-19 (COVID-19) Vaccine (Sf9 Cells) Coronavirus disease 19 infection SARS-CoV-2 vaccine (Sf9 Cell, COVID-19), Jiangsu Province Centers for Disease Control and Prevention alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Jiangsu Province Centers for Disease Control and Prevention, West China Hospital China 2020-11-17 2021-11-18 ChiCTR2000039994, JSVCT099, NCT04640402 Phase 2 Clinical Recruiting 1 12 Months 960 Fanyue Meng, Doctor, Fengcai Zhu, Doctor, Wei Wang 2020-11-24
Evaluation of respiratory Tele-rehabilitation in patient with COVID-19 Coronavirus disease 19 infection Diaphragmatic breathing exercise alone, Incentive spirometry exercise alone, Seated arm reaches alone, Sit to stand squats alone, Standing heel raises alone, Standing marching alone, Wall pushups alone, respiratory tele-rehabilitation alone, video conferencing program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mashhad University of Medical Sciences Iran 2020-11-21 IR.MUMS.NURSE.REC.1399.052, IRCT20200711048077N1 Phase Not Applicable Recruiting 1 60 Ali khorsand vakilzadeh, Fateme Rangani, Mohsen Tafaghodi 2020-11-23
Quality of life in post covid affected patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sri Ramachandra University India 2020-11-17 CTRI/2020/11/029188 Phase Not Applicable Not yet recruiting 1 500 Suja Lakshmanan 2020-11-27
Psychological effect of COVID 19 on Positive female patient Anxiety disorder, Coronavirus disease 19 infection, Psychiatric disorder Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Medical Sciences Patna India 2020-11-25 CTRI/2020/11/029200 Phase Not Applicable Not yet recruiting 1 25 Dr Poonam Kumari 2020-11-23
LATTICE: To determine the impact of latent tuberculosis on severity and outcomes in patients with suspected SARS-COV-19 infection Coronavirus disease 19 infection, Mycobacterium tuberculosis infection Interferon gamma release assay alone, Mantoux test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences India 2020-11-30 CTRI/2020/11/029203, LATTICE Phase Not Applicable Not yet recruiting 1 300 Dr Pawan Tiwari, Dr Randeep Guleria, Dr Shweta Bhopale 2020-11-27
An observational study to determine the association of vaccine coverage with the prevalence of SARS-CoV-2 infection Coronavirus disease 19 infection BCG vaccine alone Utano National Hospital Japan Phase Not Applicable Status not specified 1 2020-11-18