Last updated: Dec 26, 2020 - 02:00 GMT

Title Indication Intervention Actions PatientSelection Sponsor Collaborator Country StartDate EndDate Identifiers Phase Recruitment Status Sites Trial Duration Enrollment Count Contacts LastChanged
Ampligen in Chronic Fatigue Syndrome Chronic fatigue syndrome, Coronavirus disease 19 infection rintatolimod alone 2,5-Oligoadenylate synthetase stimulator, Interferon type I receptor agonist, Ribonuclease stimulator, TLR-3 agonist Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) AIM ImmunoTech Inc US AMP 511, NCT00215813 Phase 3 Clinical Recruiting 2 Ann Marie Coverly, Charles Lapp, MD, Charles W. Lapp, M.D., Daniel Peterson, M.D., Daniel Peterson, MD, Diane Young 2020-10-27
NRVR: Virtual Reality Study - COVID-19 Protocol Coronavirus disease 19 infection virtual reality based cognitive activity alone, virtual reality based physical activity alone Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Southern California US 2019-03-19 2021-02-17 HS17-00354, NCT04678778, NRVR Phase Not Applicable Recruiting 1 22 Months 11 Ashwin Sakhare, BS, Joy A Stradford, MS, Judy Pa, PhD, Sandra Phung, BA 2020-12-25
Implementation of a Respiratory Physiotherapy Program in Post COVID-19 Patients Through Tele-assistance Anxiety disorder, Coronavirus disease 19 infection, Dyspnea chest physiotherapy post-covid19 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Universidad Europea De Madrid Spain 2021-01-01 2021-08-01 20/139, NCT04678700 Phase Not Applicable Recruiting 1 7 Months 40 Marta de la plaza, Marta de la plaza, IP 2020-12-25
COVID-19 and Tissue Damage in Vital Organs Coronavirus disease 19 infection liver, lung, heart, kidney biopsy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dokuz Eylul University Turkey 2021-01-01 2022-01-01 COVID-19.PMB, NCT04678687 Phase Not Applicable Not yet recruiting 1 12 Months 10 Ali N Gökmen, MD, PhD, Aylin Erol, Begüm Ergan, MD, PhD, Bilgin Cömert, MD, PhD, Bişar Ergün, MD, PhD, Eyüp S Uçan, MD, PhD, Fırat Bayraktar, MD, PhD, Mehmet N Yakar, MD, PhD, Mehmet Nuri Yakar, Safiye Aktaş, MD, PhD, Özde E Gökbayrak 2020-12-25
The use of oxygen-enrich water in therapy of patients with Covid 19 Coronavirus disease 19 infection oxygen-rich water therapy alone, usual drug treatment alone Ahvaz University of Medical Sciences Iran 2020-12-21 IR.AJUMS.REC.1399.658, IRCT20201125049486N1 Phase 3 Clinical Recruiting 1 44 Masoud Veissi, Mehdi Ahmadi Moghadam 2020-12-25
COVIDPROBLEM: Evaluation of Two Versions of a Digital Problem Solving Tool for the General Public Specific for the COVID-19 Pandemic Coronavirus disease 19 infection advanced graphical interface alone, digital problem solving alone Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Karolinska Institutet Stockholm County Council Sweden 2020-08-31 2020-11-30 COVIDPROBLEM, COVIDPROBLEM, NCT04677270 Phase Not Applicable Completed 1 3 Months 397 Martin Kraepelien, PhD 2020-12-25
Stay Active Physical Activity Program Coronavirus disease 19 infection Garmin wearable physical activity monitor alone, classroom intervention alone, family support alone Healthy volunteers accepted The Childrens Mercy Hospital US 2020-10-05 2021-03-30 NCT04675658, STUDY00001495 Phase Not Applicable No longer recruiting 1 5 Months 515 Jordan Carlson, PhD 2020-12-25
Analysing the Psychosocial Effects of COVID-19 Pandemic on Dental Professionals Using the Turkish Version of the Fear of COVID-19 and Coronavirus Anxiety Scales Anxiety disorder, Coronavirus disease 19 infection dental professionals psychosocial effect analysis alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Suleyman Demirel university Turkey 2020-10-16 2020-10-23 355, NCT04674644 Phase Not Applicable Completed 1 813 esra Oz, Assist Prof 2020-12-25
Measurement of Agricultural and Dietary Glyphosate Exposure Among Pregnant Women Coronavirus disease 19 infection organic diet intake alone Healthy volunteers accepted, Female, Young Adults (18-44 yrs) Boise State University National Institute Of Environmental Health Sciences US 2021-01-31 2022-08-31 K01ES028745, NCT04155463 Phase Not Applicable Not yet recruiting 1 19 Months 40 Cynthia Curl, PhD 2020-12-25
Study of Correlation Between Markers of Coagulation and Clinical Severity in COVID-19 Blood clotting disorder, Coronavirus disease 19 infection, Multiple organ failure Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Smt. NHL Municipal Medical College Sardar Vallabhbhai Patel Institute of Medical Science and Research India 2020-12-28 CTRI/2020/12/029984 Phase Not Applicable Not yet recruiting 1 100 DR AKASH J JANI, DR PALTIAL PALAT 2020-12-25
BubblePAPR: Evaluating Bubble-PAPR for Healthcare Workers Coronavirus disease 19 infection Bubble-PAPR alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Manchester University NHS Foundation Trust University of Manchester UK 2021-02-01 2021-06-02 B00991, BubblePAPR, NCT04681365 Phase Not Applicable Not yet recruiting 2 4 Months 66 2020-12-25
Experiences of the patients and pharmacists with respect to medicine supply during COVID-19 pandemic Coronavirus disease 19 infection, Diabetes mellitus, Heart disease, Hypertension Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Manipal College of Pharmaceutical Sciences India 2021-01-14 CTRI/2020/12/029901 Phase Not Applicable Not yet recruiting 1 30 Dr Girish Thunga P, Manasvini R 2020-12-25
This study will help investigators in understanding how this disease progresses and why some became sicker. This study may also help in the development of novel therapy Coronavirus disease 19 infection, Viral pneumonia biochemical analysis alone, direct enzyme-linked immunosorbent assay alone, fluorometric assay alone, free radical assay alone, mass spectrometry alone, quantitative protein concentration estimation alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Malaria Research All India Institute of Medical Sciences, Raipur India 2020-12-24 CTRI/2020/12/029983 Phase Not Applicable Not yet recruiting 1 100 Sajal De 2020-12-25
DIADA: Scaling Up Science-based Mental Health Interventions in Latin America Coronavirus disease 19 infection, Depression Laddr, Square2 Systems alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dartmouth-Hitchcock Medical Center Javeriana University, The National Institute of Mental Health Colombia 2018-02-13 2021-04-30 1U19MH109988, 1U19MH109988 D18019, DIADA, NCT03392883 Phase Not Applicable No longer recruiting 6 38 Months 3091 Carlos Gomez-Restrepo, MD, Lisa A Marsch, PhD, Lisa A. Marsch 2020-12-25
Experiences and readiness of the volunteers during the COVID-19 in Bengaluru Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Manipal Academy of Higher Education India 2021-01-12 CTRI/2020/12/029982 Phase Not Applicable Not yet recruiting 1 30 Dr Sumit Kumar, Dr Zeenath Roohi 2020-12-25
Study to look for cardiovascular manifestations of COVID Cardiovascular disease, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute Of Medical Sciences, Rishikesh India 2020-12-28 CTRI/2020/12/029981 Phase Not Applicable Not yet recruiting 1 100 Rohit Walia 2020-12-25
A study on stress during work and tiredness in health care workers working in covid units of the university teaching hospital of south India Acute stress disorder, Coronavirus disease 19 infection, Fatigue Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Manipal College of Health Professions Kasturba hospital India 2021-01-01 CTRI/2020/12/029900 Phase Not Applicable Not yet recruiting 1 147 Mr Manjuesh U Nayak, Ms Pratibha todur 2020-12-25
Self-prone positioning to reduce need of ventilatory support in COVID-19 patients Coronavirus disease 19 infection guideline based COVID-19 treatment alone, self-prone positioning alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences Bhubaneswar India 2020-12-27 CTRI/2020/12/029898 Phase Not Applicable Not yet recruiting 1 190 Dr Upendra Hansda 2020-12-25
Analysis of COVID-19 features in HRCT Chest of patients who have no evidence of Tuberculosis infection and comparison between COVID and Tuberculosis imaging features in COVID patients Coronavirus disease 19 infection, Mycobacterium tuberculosis infection high-resolution computed tomography alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) KIMS Hospital Kalinga Institute of Medical Sciences India 2021-01-01 CTRI/2020/12/029970 Phase Not Applicable Not yet recruiting 1 50 Dr Sudhansu Sekhar Mohanty 2020-12-25
To study the effectiveness of pulmonary rehabilitation program in people who have recovered from COVID-19 Pneumonia and Acute Respiratory Distress Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia pulmonary rehabilitation program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Government Kilpauk Medical College India 2020-12-22 CTRI/2020/12/029957 Phase Not Applicable Not yet recruiting 1 217 Dr P Thirunavukkarasu, Padma Rani S 2020-12-24
COVID-19 Seroprevalence Survey among Cancer Patients and Caregivers in Cancer Center Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) HRH Princess Chulabhorn College of Medical Science, Chulabhorn Royal Academy, Ministry of Higher Education, Science, Research and Innovation Thailand 2020-12-01 TCTR20201214005 Phase Not Applicable Not yet recruiting 1 400 Teerapat Ungtrakul 2020-12-24
Web Based Survey to assess the mental health status of health sciences students during COVID-19 Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression Healthy volunteers accepted, Young Adults (18-44 yrs) Manipal Academy of Higher Education, Manipal College of Pharmaceutical Sciences India 2021-01-14 CTRI/2020/12/029956 Phase Not Applicable Not yet recruiting 1 1000 Dr Kanav Khera, Siddheesh Rajpurohit 2020-12-24
Cereset Research In Healthcare Workers During COVID-19 Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection Cereset Research system alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Wake Forest University Health Sciences, US Wake Forest Baptist Medical Center US 2021-02-28 2022-02-28 IRB00066997, NCT04682197 Phase Not Applicable Not yet recruiting 1 12 Months 100 Charles H Tegeler, MD, Study Coordinator 2020-12-25
Effect of the COVID-19 on services offered to pregnant women and their mental health in urban areas of Hyderabad: A study Coronavirus disease 19 infection, Psychiatric disorder Female, Young Adults (18-44 yrs) Manipal Academy of Higher Education India 2021-01-01 CTRI/2020/12/029955 Phase Not Applicable Not yet recruiting 1 300 Dr Arathi Rao, Dr Sudhamshi Beeram, Dr Sumit Kumar 2020-12-24
EUROCOV: Risk Stratification of Patients With Suspected COVID-19 Presenting to the ED Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) European Society for Emergency Medicine (EUSEM) Research Network Italy, France, Finland, Greece, Belgium, Croatia 2020-03-09 2021-01-31 123456, EUROCOV, NCT04682093 Phase Not Applicable Recruiting 6 10 Months 8000 Said LARIBI, MD, PhD 2020-12-24
Antibiotic Prescription in Children Hospitalized for Community-acquired Pneumonia Coronavirus disease 19 infection, Viral pneumonia Antibiotic treatment alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) ARCIM Institute Academic Research in Complementary and Integrative Medicine Gemeinschaftskrankenhaus Herdecke Germany 2020-12-31 2024-12-31 NCT04681339, PKA-03 Phase Not Applicable Not yet recruiting 2 48 Months 200 Alfred Längler, Professor, Jan Vagedes, Dr, Jan Vagedes, MD, Dr 2020-12-24
Survival Analysis of COVID-19 patients admitted in a Tertiary Government Hospital in Nueva Ecija: A Preliminary Report on the Compassionate use of Remdesivir Coronavirus disease 19 infection remdesivir alone COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Dr. Paulino J. Garcia Memorial Research and Medical Center Philippines 2021-01-22 2021-03-31 PHRR201221-003217 Phase Not Applicable Not yet recruiting 1 2 Months Huberto Franco Lapuz, Jem Marie L Magno, Lailanie Mogol Gustilo, Lordel M Arriola, Marilou L Pascual, Melvin Ricio Estolano, Reina Elizabeth L De Guzman 2020-12-24
Use of soapy nasal irrigation in COVID-19 positive cases to reduce viral load in nasopharynx and oropharynx Coronavirus disease 19 infection surfactant-saline nasal douching alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) GMERS Medical College and Hospital India 2020-12-28 CTRI/2020/12/029954 Phase 3 Clinical Not yet recruiting 1 100 Dr Nimisha Nimkar 2020-12-24
Cost Burden of COVID-19 in a Tertiary care hospital Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Manipal Academy of Higher Education India 2021-01-15 CTRI/2020/12/029926 Phase Not Applicable Not yet recruiting 1 500 Chaitanyamayee Kalakota, Dr Mahadev Rao, Dr Muralidhar Varma, Dr Rajesh V 2020-12-25
SAVE-MORE: suPAR-Guided Anakinra Treatment for Management of Severe Respiratory Failure by COVID-19 Coronavirus disease 19 infection, Lower respiratory tract infection, Respiratory failure anakinra alone Type I IL-1 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hellenic Institute for the Study of Sepsis Greece 2020-12-21 2021-12-20 NCT04680949, SAVE-MORE, SAVE-MORE Phase 3 Clinical Not yet recruiting 23 12 Months 600 Aggeliki Rapti, Aikaterini Argyraki, Aikaterini Dimakou, Aikaterini Masgala-Seferli, Anastasia Antoniadou, Antonia Koutsoukou, Archontoula Fragkou, Evangelos Giamarellos-Bourboulis, MD, PhD, Evangelos Kostis, Evdoxia Kyriazopoulou, MD, MSc, PhD, Garyfallia Poulakou, George Dalekos, George Tsoukalas, Georgios Chrysos, Georgios Marathonitis, Glykeria Tzatzagou, Haralampos Milionis, Helen Sambatakou, Ilias Kainis, Ilias Papanikolaou, Ioannis Bliziotis, Ioannis Kalomenidis, Karolina Akinosoglou, Malvina Lada, Maria Chini, Michael Samarkos, Michalis Doumas, Periklis Panagopoulos, Simeon Metallidis, Vasileios Kotsis, Vasiliki Tzavara, Zoi Alexiou 2020-12-24
A clinical trial of a new product to understand the effectiveness and safety to manage the symptoms of COVID-positive adult patients Coronavirus disease 19 infection, Respiratory distress syndrome Omshreeraj (Omshree Sidha Hospital) alone, conventional treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Omshree Sidha Hospital India 2021-01-15 CTRI/2020/12/029902 Phase 2 Clinical Not yet recruiting 1 80 Dr Deepa Subramanian, Dr Giriraja KV, Mr Jose M J 2020-12-24
The Diagnostic Accuracy of Lung Ultrasound among ESI 1 and ESI 2 patients as a Screening Tool for COVID-19 at the Emergency Department of Southern Philippines Medical Center, Davao city, Philippines Coronavirus disease 19 infection Lung ultrasound alone Southern Philippines Medical Center Philippines 2020-06-02 2020-11-20 PHRR201216-003072 Phase Not Applicable Status not specified 1 5 Months Christian Jake Alce, Vladimir Datangel Raguindin 2020-12-24
Describing COVID-19 Infection Rates Amongst Operating Room Staff Assigned in Different Operating Room Complexes at a Tertiary Hospital Coronavirus disease 19 infection Southern Philippines Medical Center Philippines 2020-11-09 2021-02-09 PHRR201215-003198 Phase Not Applicable Not yet recruiting 1 3 Months Leonil Ferdinand A. Sembrano 2020-12-24
INSPIRES: Hearing Health Trial - Innovative Psychological Intervention to Reduce Stigma in Hearing Health Trial Coronavirus disease 19 infection, Hearing loss Self-affirmation alone Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Manchester UK 2021-01-10 2021-07-10 2020-10597-17109, INSPIRES, NCT04680845 Phase Not Applicable Not yet recruiting 1 6 Months 3000 Cath Wright, Christopher Armitage, Christopher J Armitage, PhD, Kevin Munro, PhD 2020-12-25
Chronic Pain Management In Primary Care Using Behavioral Health Consultants Coronavirus disease 19 infection, Pain brief cognitive behavioral therapy for chronic pain (BCBT-CP) alone, telephone booster alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Texas Health Science Center San Antonio 59th Medical Wing, Brooke Army Medical Center, Carl R Darnall Army Medical Center, Defense Health Agency, Massachusetts General Hospital, Uniformed Services University of the Health Sciences US 2021-02-28 2025-02-28 HSC20200520H, NCT04680000 Phase Not Applicable Not yet recruiting 2 48 Months 716 Abby Blankenship, PhD, Alan Peterson, PhD, Cindy McGeary, PhD, Don McGeary, PhD, Donald J McGeary, PhD, Donald McGeary, PhD, Jeff Goodie, PhD, Stacey Young-McCaughan, PhD 2020-12-25
Adapting and Adopting Highly Specialized Pediatric Eating Disorder Treatment to Virtual Care: Implementation Research for the COVID-19 Context and Beyond Anorexia nervosa, Coronavirus disease 19 infection virtual family-based treatment alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) McMaster University Canada 2021-01-31 2021-12-31 12722, NCT04678843 Phase 0 Clinical Not yet recruiting 1 11 Months 36 Danielle Pellegrini, MPH, Jennifer Couturier, MD MSc, Laura Grennan, BSc 2020-12-25
Comparison of Viral Particle Dispersion Following Administration of an MDI or Nebulizer in Subjects With COVID-19 Coronavirus disease 19 infection Metered-dose inhaler with spacer alone, Nebulizer with filtered mouthpiece alone, albuterol sulfate alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Theravance Biopharma Inc US 2021-01-31 2021-02-28 0192, NCT04681079 Phase Not Applicable Not yet recruiting 1 1 Month 10 Medical Monitor, Theravance Biopharma Call Center 2020-12-24
Building Trauma Resilience Among Nurses and Personal Support Workers During COVID-19 Coronavirus disease 19 infection, Injury STEP Program Psychotherapy alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) St Michaels Hospital Providence Health Care Canada 2021-01-31 2022-02-28 NCT04682561, STP-01 Phase Not Applicable Not yet recruiting 1 13 Months 40 Michael Morton, HBSc, Sakina Rizvi, MACP, PhD, Sakina Rizvi, PhD 2020-12-25
Role of Mega Dose of Vitamin C in Critical COVID-19 Patients Coronavirus disease 19 infection vitamin C alone University of Lahore, Main Campus Pakistan 2020-11-02 2021-01-10 IRBEC/BIH/09-2020, NCT04682574 Phase 2 Clinical Recruiting 1 2 Months 15 Dr Muhammad Mansoor Hafeez, Muhamma Asim Rana, MBBS, MRCP, Muhammad Asim Rana, MBBS, MRCP, Muhammad Mansoor Hafeez, MBBS 2020-12-24
EndoCom: Impact of Digital Communication Assist Tools in Endoscopic Team Communication Coronavirus disease 19 infection DECT headset alone, enhanced communication alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Universitat Ulm Germany 2020-07-01 2021-02-15 122020, EndoCom, NCT04680858 Phase Not Applicable Recruiting 1 7 Months 500 Thomas Seufferlein 2020-12-25
Hematological and biochemical markers as poor outcome predictors in COVID-19 Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) pramukhswami medical college Shri Krishna Hospital India 2020-12-25 CTRI/2020/12/029897 Phase Not Applicable Not yet recruiting 1 1000 Labani Ghosh, Nirav Thakar 2020-12-25
To study Covid disease pattern in health care personnel working in a dedicated Covid Hospital Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Medical Sciences India 2020-12-25 CTRI/2020/12/029896 Phase Not Applicable Not yet recruiting 1 75 Ashish Bindra 2020-12-25
Stress of Thai Dentist During COVID-19 Pandemic in Thailand Acute stress disorder, Coronavirus disease 19 infection Healthy volunteers accepted Chulalongkorn University Thailand 2020-04-17 TCTR20201215003 Phase Not Applicable Completed 1 380 Keskanya Subbalekkha 2020-12-24
Virtual medical system for cancer patient monitoring and caregiver support during the COVID-19 pandemic Cancer, Coronavirus disease 19 infection Virtual medical system alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) HRH Princess Chulabhorn College of Medical Science, Chulabhorn Royal Academy Thailand 2021-01-01 TCTR20201215001 Phase 3 Clinical Not yet recruiting 1 1000 Teerapat Ungtrakul 2020-12-24
PICNIC: Evaluating the Impact of EnteraGam In People With COVID-19 Coronavirus disease 19 infection EnteraGam (Entera Health) alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Entera Health Hospital del Mar Medical Research Institute, Lemus Buhils SL Spain, US 2021-01-01 2021-06-30 NCT04682041, PICNIC, PICNIC STUDY Phase Not Applicable Not yet recruiting 2 6 Months 420 Maria Tintoré, Netanya S. Utay, MD, Roberto Güerri Fernández, MD, PhD 2020-12-24
ACT: Anti-COVID-19, AKS-452 - ACT Study Coronavirus disease 19 infection AKS-452 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) University Medical Center Groningen Akston Biosciences Corp Netherlands 2021-01-18 2021-06-30 ACT, NCT04681092, NL2020-005997-82 Phase 1/Phase 2 Clinical Not yet recruiting 1 5 Months 130 Gooitzen M van Dam, MD, PhD, Hendrikus H Boersma, PharmD, PhD, Schelto Kruijff, MD, PhD 2020-12-24
Safety and Efficacy Evaluation of a Low-cost CPAP Device for Hypoxemic COVID-19 Patients: A Pilot Study (OxyJet) Coronavirus disease 19 infection, Hypoxia, Viral pneumonia OxyJet venturi-based positive pressure ventilator alone, continuous positive airway pressure therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Bangladesh University of Engineering and Technology Dhaka medical college Bangladesh 2020-12-30 2021-05-01 BME-BUET-003, NCT04681859 Phase Not Applicable Not yet recruiting 1 4 Months 40 Dr. Forhad Uddin Hasan Chowdhury, MBBS, FCPS, Dr. Md. Khairul Islam, MBBS, FCPS, MCPS, Dr. Md. Khairul Islam, MBBS,MCPS,FCPS, Dr. Md. Mohiuddin Sharif, MBBS, MPA, Dr. Robed Amin, MBBS, FCPS, Dr. Taufiq Hasan, PhD 2020-12-24
A phase I/II clincial trial of Heplisav for the treatment of Covid-19 Coronavirus disease 19 infection Heplisav alone, vaccine (Dynavax adjuvant CpG1018, Bordetella pertussis infection), Serum Institute of India alone TLR-9 agonist Serum Institute of India Privated Ltd Dynavax Technologies Corp Phase 1/Phase 2 Clinical Recruiting 0 216 2020-12-24
Occupational Balance, Fear and Agoraphobia (OB) Agoraphobia, Coronavirus disease 19 infection, Phobia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hacettepe University Turkey 2020-05-04 2020-06-04 2020/185, NCT04681261 Phase Not Applicable Completed 2 1 Month 699 Özgü İnal 2020-12-24
Estimating Prevalence of COVID-19 Infection and SARS-CoV-2 Antibodies in MS Patients Coronavirus disease 19 infection, Multiple sclerosis ocrelizumab alone B-lymphocyte antigen CD20 inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) NYU Langone Health US 2021-01-31 2021-12-31 20-01799, NCT04682548 Phase Not Applicable Not yet recruiting 1 11 Months 1000 Ilya Kister, MD, Zoe Rimler 2020-12-24
Evaluation of the Effect of Anatolian Propolis on COVID-19 in Healthcare Professionals Coronavirus disease 19 infection Anatolian Propolis alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ataturk University Turkey 2020-12-25 2021-01-25 ATATURKU2, NCT04680819 Phase Not Applicable Not yet recruiting 1 1 Month 50 Abdullah Osman KOCAK, Ataturk University Osman, Ozlem BILIR 2020-12-24
A Single Oral Dose Study of RP-7214, a DHODH Inhibitor in Healthy Adult Subjects Coronavirus disease 19 infection RP-7214 alone Dihydroorotate dehydrogenase inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Rhizen Pharmaceuticals SA US 2020-12-31 2021-06-30 NCT04680429, RP7214-2002 Phase 1 Clinical Not yet recruiting 1 6 Months 18 Prajak Barde, MD 2020-12-24
REHABCOV: Rehabilitation Required Due to Clinical Disorders After Severe SARS-CoV-2 Infection Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopitaux Universitaires de Strasbourg France 2020-05-19 7725, NCT04681755, REHABCOV Phase Not Applicable Recruiting 1 55 Charlotte POUSSARDIN, MD, François SEVERAC, MD, Saïd CHAYER, PhD, HDR, Walid Oulehri, MD 2020-12-24
A retrospective study to evaluate the clinical and microbiological outcomes of standard doses of ivermectin in severe COVID-19 patients with pneumonia Coronavirus disease 19 infection, Viral pneumonia azithromycin alone, beta-interferon alone, hydroxychloroquine alone, ivermectin alone, lopinavir + ritonavir alone, remdesivir alone Chloride channel modulator, HIV protease inhibitor Hospital Clinic of Barcelona Spain Phase Not Applicable Status not specified 1 26 2020-12-24
COVIDIAGNOSTIX: Sensitivity Evaluation of Serological Tests for Sars-Cov2 Coronavirus disease 19 infection health technology assessment alone Healthy volunteers accepted Istituto Ortopedico Galeazzi Spa Italy 2020-11-18 2021-11-30 COVIDIAGNOSTIX, COVIDIAGNOSTIX, NCT04678024 Phase Not Applicable Recruiting 1 12 Months 410 Giuseppe Banfi 2020-12-24
COVID - EHPAD: Study of Symptoms Linked to Covid-19 in Residents and Professionals in EHPAD, Associated With a Dual Diagnostic Approach by PCR and Serology: a Cohort in Ile-de-France Coronavirus disease 19 infection ELISA alone, RT-PCR alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gérond'if France 2020-04-05 2021-03-31 2020-A01027-32, COVID - EHPAD, NCT04677283 Phase Not Applicable Recruiting 1 11 Months 2020 Isabelle Dufour, Margot Bobin, Martine LE NOC - SOUDANI, MD 2020-12-24
Study to Assess Safety, Tolerability and Pharmacokinetics of XC-7 in Healthy Volunteers Coronavirus disease 19 infection XC-7 (NP Therapeutics) alone Healthy volunteers accepted, Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) NP Therapeutics Russian Federation 2020-12-31 2021-02-28 COVID-XC7-01, NCT04679493 Phase 1 Clinical Not yet recruiting 1 2 Months 16 Elena Smolyarchuk, MD, PhD, Vladimir Nebolsin, PhD 2020-12-24
COVID-19 Vaccine Study: Safety and Immunogenicity of AdCOVID in Healthy Adults (COVID-19 Vaccine Study) Coronavirus disease 19 infection AdCOVID alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Altimmune Inc University of Alabama at Birmingham 2020-12-31 2022-02-28 ALT-501-101, COVID-19 Vaccine Study, NCT04679909 Phase 1 Clinical Not yet recruiting 0 14 Months 180 Altimmune CTM 2020-12-25
ANTIICIPATE: Antiviral and Immunomodulatory Interferon-Beta in high-risk COVID-19 patients Coronavirus disease 19 infection REBIF alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) Istituto Nazionale Per Le Malattie Infettive "Lazzaro Spallanzani", Istituto Superiore di Sanita, Merck Healthcare KGaA Italy 2020-11-06 2020-003872-42, ANTIICIPATE Phase 2 Clinical Recruiting 1 Steering committee of the ANT study 2020-12-25
ProCOVRA: Prognostic Evaluation of COVID-19 in Rheumatoid Arthritis Patients Coronavirus disease 19 infection, Rheumatoid arthritis Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Montpellier France 2020-12-01 2021-02-01 NCT04679272, ProCOVRA, RECHMPL20_0682 Phase Not Applicable Recruiting 1 2 Months 2000 Padern Guillaume, physician 2020-12-24
COVitaminD: Prevention of complications from COVID-19 in cancer patients under active treatment Cancer, Coronavirus disease 19 infection vitamin D alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Istituto Europeo di Oncologia SrL Italy 2020-11-16 2020-002119-23, COVitaminD, IEO1253 Phase 2 Clinical Recruiting 1 80 CLINICAL STUDIES AND ACTIVITIES OFFICE 2020-12-25
Effects on the clinical evolution of patients with respiratory infection secondary to the Sars-CoV-2 virus, when they are maintaining communication with family/friends through mobile devices compared to patients not having an option of communication Coronavirus disease 19 infection, Respiratory tract infection Video calls alone, mobile device alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Autonomous University of Mexico ISSSTE Centro Medico Nacional 20 de Noviembre American Samoa 2020-12-22 2021-03-15 FM/DI/084/2020, SLCTR/2020/026, U1111-1259-9918 Phase Not Applicable Not yet recruiting 1 2 Months 386 Miguel Angel Fernández Ortega 2020-12-24
PRIDE - Pilot Trial of an Online Digital Problem-solving Intervention for School-going Adolescents in Goa, India Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression POD Adventures alone Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs) Sangath Harvard Medical School, London School of Hygiene and Tropical Medicine, University of Sussex US 2020-12-18 2021-03-31 106919/Z/15/Z, NCT04672486, PG_2020_69 Phase Not Applicable Not yet recruiting 1 3 Months 120 Daniel Michelson, PhD, Pattie P Gonsalves, MSc, Vikram Patel, PhD 2020-12-24
Mask Hypoxia in Subjects Using Masks to Prevent Infection Spread Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of New Mexico US 2021-01-01 2021-12-31 20-456, NCT04670484 Phase Not Applicable Not yet recruiting 1 12 Months 30 Asad Ikram, MD, Elizabeth Macri, MD, Macri Elizabeth, MD, Michel Torbey, MD 2020-12-24
Risk of Infection of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), COVID-19, in a Massive Musical Show With Transmission Prevention Measures Coronavirus disease 19 infection Participate in a massive musical event alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) FUNDACIÓN FLS DE LUCHA CONTRA EL SIDA, LAS ENFERMEDADES INFECCIOSAS Y LA PROMOCIÓN DE LA SALUD Y LA CIENCIA Germans Trias i Pujol Hospital, Universitat de Barcelona Spain 2020-11-30 2020-12-22 NCT04668625, PRIMACOV Phase Not Applicable No longer recruiting 1 1000 Bonaventura Clotet Sala, PhD, MD, Boris Revollo Barriga, PhD, MD, Dr. Ignacio Blanco Guillermo, Dr. Roger Paredes Deiros, Dra. Andrea Alemany Ortiz, Dra. Lidia Ruiz Tabuenca, Josep Mª LLIBRRE CODINA, PhD, MD 2020-12-24
Immunological Characteristics of COVID-19 Patients Coronavirus disease 19 infection BCS XP analyzer alone, CellaVision system alone, Cobas analyzer alone, IVD ELISA kit alone, Sysmex XN 3100 hematology analyzer alone, biochemical test alone, coagulation test alone, electrochemiluminescence immunoassay  alone, enzyme-linked immunosorbent assay alone, flow cytometry alone, hemogram test alone, immunophenotyping alone, microscope alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The University Clinic of Pulmonary and Allergic Diseases Golnik National Institute Of Chemistry Slovenia 2020-05-07 2023-05-07 GOLNIK_COVID-19, NCT04679428 Phase Not Applicable Recruiting 1 36 Months 230 Ajda Demšar, MsC, Aleš Rozman, MD, PhD, Ana Koren, PhD, Barbara Bitežnik, MD, Gregor Ostanek, Gregor Vlačić, MD, Izidor Kern, MD, Katarina Osolnik, MD, Katja Adamič, MD, Katja Mohorčič, MD, Kristina Cerk Porenta, MD, Matija Rijavec, PhD, Matjaž Fležar, MD, PhD, Mile Kovačevič, MD, Mojca Bizjak, MD, Nina Frelih, MD, Peter Kopač, MD, Peter Korošec, PhD, Petra Svetina, MD, Pika Meško Brguljan, PhD, Rok Lombar, MD, Sanja Grm Zupan, MD, Tanja Šubic, M.Sc. Nursing, Tina Jerič, MD, Tomaž Hafner, MD, Urška Bidovec Stojkovič, PhD, Vesna Nikolić, MD 2020-12-24
COVID-19 Long-Haulers Study Coronavirus disease 19 infection leronlimab alone CCR5 chemokine antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) CytoDyn Inc Amarex Clinical Research US 2020-12-21 2021-03-23 CD15_COVID-19, NCT04678830 Phase 2 Clinical Not yet recruiting 1 3 Months 102 Dr Chris Recknor, Dr Mahboob Rahman, kush Dhody, MBBS, MS, CCRA 2020-12-24
A clincial trial of cannabinoid (nasal/sol-gel, COVID-19/pain/inflammation/seizures/neurological disorders), PreveCeutical for the treatment of Covid-19 Coronavirus disease 19 infection cannabinoid (nasal/sol-gel, COVID-19/pain/inflammation/seizures/neurological disorders), PreveCeutical alone PreveCeutical Medical Inc Phase Not Applicable Planned 0 2020-12-23
Efficacy and Safety of hzVSF-v13 in Moderate-to-Severe Patients With COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia chimeric humanized virus suppressing factor, ImmuneMed alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) ImmuneMed Inc Indonesia 2020-12-31 2021-05-31 HZVSF_V13-0007, NCT04679415 Phase 2 Clinical Not yet recruiting 3 5 Months 63 Byoungok Ahn, phD, Erizal Sugiono, Prasenohadi, phD, Sri Dhuny Atas Asri, phD, Wahyuningsih Suharno, phD 2020-12-25
Efficacy and Safety of hzVSF-v13 in Patients With COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia Standard of Care alone, chimeric humanized virus suppressing factor, ImmuneMed alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) ImmuneMed Inc South Korea 2021-03-31 2021-07-31 IM-HZVSF-V13-0004, NCT04679350 Phase 2 Clinical Not yet recruiting 3 4 Months 48 Byoungok Ahn, phD, Jae Seok Park, phD, Jihoon Hwang, Kwan Ho Lee, phD, Yeon Suk Kim, phD 2020-12-23
Evaluation of the effect of Propolis COVID-19 Coronavirus disease 19 infection propolis (Shahdineh Golha Company) alone Kurdistan University of Medical Sciences Iran 2020-12-05 IR.MUK.REC.1399.168, IRCT20190415043279N9 Phase 3 Clinical Recruiting 1 72 Dr. Afshin Maleki, Dr. Vahid Yousefinejad, Pezhman Sharifi, Sabah Hasani, Vahid Yousefinejad 2020-12-23
Study on Kidney Disease and Enviromental Chemical Coronavirus disease 19 infection, End stage renal disease blood test alone, urine test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Seoul National University Hospital South Korea 2020-06-01 2021-12-31 NCT04679168, SKETCH Phase Not Applicable Recruiting 1 19 Months 310 Jeonghwan Lee, Dr., Jeonghwan Lee, Prof., Jung Pyo Lee, M.D., Ph.D, Jung Pyo Lee, M.D., Ph.D., Yaerim Kim, Prof. 2020-12-25
Determination of the effectiveness of a mouthwash and nasal spray in clinical improvement, decrease in the number of viruses and their prolonged action in patients with Covid-19 Coronavirus disease 19 infection Oral Antiseptic alone, mouthwash / gargle alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Uel Universidade Estadual De Londrina Brazil 2020-11-16 37277420.0.0000.5231, 4.325.682, RBR-8tygcz7, U1111-1260-7525 Phase Not Applicable Recruiting 1 45 Bernardo da Fonseca Orcina, Paulo Sérgio da Silva Santos 2020-12-24
The effect of Montelukast on COVID-19 disease activity Coronavirus disease 19 infection Airokast (Abidi pharma) alone, standard therapy alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dr.Abidi's Pharmaceutical Laboratories Iran 2020-12-21 IR.MUI.MED.REC.1399.382, IRCT20181208041886N3 Phase 3 Clinical Recruiting 1 60 Morteza Pourahmad, Seyed Amir Razavian Ardehali 2020-12-25
Efficacy and Safety of Remdesivir and Tociluzumab for the Management of Severe COVID-19: A Randomized, Controlled Trial Coronavirus disease 19 infection remdesivir plus tocilizumab COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) M Abdur Rahim Medical College and Hospital The First Affiliated Hospital of Xi'an Jiaotong University Bangladesh 2020-08-15 2021-02-28 M.A.R.M.C.D./2020/1985, NCT04678739 Phase 3 Clinical Recruiting 1 6 Months 150 Abu Taiub Mohammed Mohiuddin Chowdhury, Abu Taiub Mohammed Mohiuddin Chowdhury, MBBS, MD, Aktar Kamal, MD, PhD, Akter Kamal, MBBS, MD, PhD, Akter Kamal, MD, PhD 2020-12-23
Epidemiology and Transmission of COVID-19 Among 121 Positive Cases And 1353 Close Contacts In Penang, Malaysia: A Retrospective, Cohort Study March to April 2020 Coronavirus disease 19 infection International Medical University Malaysia 2020-12-21 2021-03-31 57231, NMRR-20-2721-57231 Phase Not Applicable Recruiting 2 3 Months Dr Shazatul Shazmin binti Samsudin, Dr Sumaira Hussain 2020-12-24
Comparison of anesthesia management and procedures during COVID19 time and one year before Anesthesia, Coronavirus disease 19 infection arterial cannulation treatment alone, blocker theraoy alone, central line cannulation treatment alone, direct laryngoscopy alone, double-lumen tube alone, epidural anesthesia alone, fibre-optic intubation alone, laryngeal mask airway therapy alone, regional block treatment alone, spinal anesthesia alone, videolaryngoscopy alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs) Tata Memorial Hospital India 2021-01-21 3600_Protocol Version 1.0, CTRI/2020/12/029887 Phase Not Applicable Not yet recruiting 1 600 Dr Anjana Wajekar, Dr Sagar Pargunde 2020-12-23
Socio-demographic profile and clinical outcome in COVID19 in a tertiary care hospital - a retrospective study Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) SRM Institutes for Medical Science India 2020-12-21 CTRI/2020/12/029882 Phase Not Applicable Not yet recruiting 1 1500 Dr PunithaVC 2020-12-24
Wellness Screening Coronavirus disease 19 infection, Depression, Psychiatric disorder Healthy volunteers accepted Hospital Wanita Dan Kanak-Kanak Sabah Malaysia 2021-01-15 2021-12-31 57594, NMRR-20-2726-57594 Phase Not Applicable Not yet recruiting 1 11 Months Assoc Prof Dr Cheah Phaik Kin, Dr Cheah Phee Kheng, Dr Fatin Salwani Zaharuddin 2020-12-24
A retrospective, cohort study on the risk factors and survival outcome of End Stage Renal Disease (ESRD) patients receiving regular maintenance hemodialysis with Covid-19 infection in Hospital Enche Besar Hajjah Khalsom, Kluang, Johor Coronavirus disease 19 infection, End stage renal disease hemodialysis alone Hospital Enche' Besar Hajjah Khalsom Malaysia 2020-12-17 2021-11-01 57507, NMRR-20-2729-57507 Phase Not Applicable No longer recruiting 1 10 Months DR CHIN HUANG HIN 2020-12-24
A phase IIb/III clinical trial, placebo-controlled study of RLF-100 in the treatment of respiratory deficiency due to COVID-19 Coronavirus disease 19 infection, Respiratory disease aviptadil (inhaled, sarcoidosis/acute lung injury/acute respiratory distress syndrome associated COVID-19), Relief Therapeutics Holding alone Adrenergic receptor antagonist, VIP receptor agonist Relief Therapeutics Holding AG US Phase 2/Phase 3 Clinical Status not specified 1 2020-12-23
A late stage clinical trial of AZD-1222 for the potential prevention of COVID-19 infection Coronavirus disease 19 infection AZD-1222 alone COVID19 Spike glycoprotein modulator Biological E Ltd India 2021-04-30 Phase Not Applicable Planned 1 25000 2020-12-23
Acute Effusive Pericarditis In COVID-19 Coronavirus disease 19 infection, Pericarditis Hospital Sungai Buloh Malaysia 2020-12-15 2021-01-25 57696, NMRR-20-2732-57696 Phase Not Applicable Status not specified 1 1 Month Dr Lavanya Narayanan 2020-12-24
Risk in COVID-19 High Risk Facilities Coronavirus disease 19 infection Healthy volunteers accepted National Institutes of Health Malaysia Malaysia 2021-01-01 2021-12-31 57599, NMRR-20-2757-57599 Phase Not Applicable Status not specified 5 12 Months Dr Nadia binti Mohamad 2020-12-24
CODIQ-My [1]: Asymptomatic Covid-19 Quarantine Digital Solution: a Proof of Concept Study Coronavirus disease 19 infection Quarantine Digital Solution alone National Institutes of Health Malaysia Malaysia 2021-04-01 2021-12-24 57684, CODIQ-1, CODIQ-My [1], NMRR-20-2761-57684 Phase Not Applicable Status not specified 1 8 Months Dr Kalaiarasu Peariasamy, Dr Mohan Dass Pathmanathan 2020-12-24
Long term functional outcomes of Malaysian COVID- 9 survivors Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Malaya Malaysia 2021-01-11 2022-11-11 57044, NMRR-20-2782-57044 Phase Not Applicable Not yet recruiting 2 22 Months 240 DR AKMAL HAFIZAH ZAMLI, Dr Anwar Suhaimi 2020-12-24
ExploreCOVID: Multicenter, exploratory, retrospective, observational study to identify optimal CT imaging biomarkers in combination with clinical markers and PCR-RT for the diagnosis and assessment of the therapeutic response of COVID-19 using artificial intelligence Coronavirus disease 19 infection, Viral pneumonia Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Heidelberg Deutsche Forschungsgemeinschaft (DFG), Deutsches Krebsforschungszentrum, German Federal Ministry of Education and Research, Mint Medical GmbH, Thoraxklinik-Heidelberg GmbH Germany 2020-12-22 DRKS00023913, ExploreCOVID, S-813/2020, U1111-1262-7515 Phase Not Applicable Not yet recruiting 4 1000 Pascal Probst 2020-12-24
Patients with SARSCOV-2 with its mRNA levels of BLIMP1 alpha and beta Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Sarojini Naidu Medical College India 2020-12-23 CTRI/2020/12/029868 Phase Not Applicable Not yet recruiting 1 55 Dr Nitu Chahuhan 2020-12-24
Comparison of a techniques named goal directed therapy with clinician guided regime for fluid management in COVID-19 critical care unit Coronavirus disease 19 infection, Hypoxia pulse pressure variation guided goal directed fluid therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences India 2020-12-18 CTRI/2020/12/029841 Phase Not Applicable Not yet recruiting 1 20 Dr Khushboo Pandey, Dr Sushma Bhatnagar 2020-12-24
COROMEC: COVID-19 Risk Assessment for Hospitalization Outcomes and Epidemiology Efficacy Coronavirus disease 19 infection ECL-19 alone, digital health (Aventyn, Inc) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Aventyn Abrazo Health Network, Baylor Health Care System, Intel Corp, Karolinska Institutet Sweden, US, India 2020-12-24 2022-06-30 CORAVT 001, COROMEC, NCT04678193 Phase 1/Phase 2 Clinical Not yet recruiting 3 18 Months 27000 Kris Vijay, MD, Michael Castro, MD, Navin Govind, Peter A McCullough, MD, Puja Chandler 2020-12-24
A Placebo-Controlled Study of TAK-919 in Healthy Japanese Adults (COVID-19) Coronavirus disease 19 infection TAK-919 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Japanese Ancestry Takeda Pharmaceutical Co Ltd Japan 2021-01-20 2022-03-11 NCT04677660, TAK-919-1501, U1111-1261-9040 Phase 1/Phase 2 Clinical Not yet recruiting 1 13 Months 200 Study Director, Takeda Study Registration Call Center 2020-12-24
A study to compare the effectiveness of two drugs, Dexamethasone versus Methylprednisolone in the treatment of moderate COVID-19 patients Coronavirus disease 19 infection, Hypoxia, Viral pneumonia dexamethasone alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) SRM University India 2020-12-20 CTRI/2020/12/029894 Phase 2 Clinical Not yet recruiting 1 50 DR R Nivetha, DR T A Vidya, Dr K T Jayakumar 2020-12-25
Response to an Upcoming COVID-19 Vaccine About How an Individual Looks Towards It Coronavirus disease 19 infection Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) NPA Govt Ayurveda College India 2020-12-26 CTRI/2020/12/029884 Phase Not Applicable Not yet recruiting 1 1500 Dr Prashant Kumar Gupta 2020-12-24
Effectiveness of Siddha Medicines on COVID-19 patients Coronavirus disease 19 infection chitrarathai kudineer siddha herbal decoction alone, notchi kudineer siddha herbal decoction alone, standard of care  alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ministry of Ayush India 2021-01-04 CTRI/2020/12/029869 Phase 2/Phase 3 Clinical Not yet recruiting 1 90 Dr A Vinothkumar, N KABILAN, SUDHA SESHAYYAN 2020-12-23
Comparison of transport medias for detecting COVID-19 positivity Coronavirus disease 19 infection Viral transport media alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tata Memorial Centre Advanced Centre For Treatment Research & Education In Cancer (Actrec) India 2020-12-28 900738, CTRI/2020/12/029885 Phase Not Applicable Not yet recruiting 1 394 Dr Amit Joshi 2020-12-24
A pragmatic, real-world study of bamlanivimab in high-risk patients with COVID-19 Coronavirus disease 19 infection bamlanivimab alone COVID19 Spike glycoprotein modulator Eli Lilly & Co US Phase Not Applicable Planned 1 2020-12-22
Professional quality of life in health care workers of ICUs during COVID-19 pandemic Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Lok Nayak Hospital, Maulana Azad Medical College India 2020-12-24 CTRI/2020/12/029873 Phase Not Applicable Not yet recruiting 1 323 Sukhyanti Kerai, sukhyanti kerai 2020-12-22
A study to see the result of planned cancer surgery in COVID-19 survivors Cancer, Coronavirus disease 19 infection, Pulmonary heart disease elective cancer surgery alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tata Memorial Hospital India 2021-01-01 3630_Protocol Version 1.1, CTRI/2020/12/029847 Phase Not Applicable Not yet recruiting 1 600 Dr J V Divatia, Dr Priya Ranganathan 2020-12-25
TeleSpA: Monitoring Spondyloarthritis With SpA-Net Coronavirus disease 19 infection, Spondylarthritis Patient initiated care alone, telemonitoring (eHealth platform SpA-Net) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Maastricht University Medical Center Dutch Arthritis Association, Medisch Spectrum Twente Enschede, Universiteit Maastricht Netherlands 2020-12-02 2022-07-31 NCT04673825, NL71041.068.19, TeleSpA Phase Not Applicable Recruiting 2 19 Months 200 A.M. van Tubergen, MD, H.E. Vonkeman, MD, K. Hermans, MD, Kasper Hermans, MD, M. Hegeman 2020-12-24
Cognitive Behavioral Therapy for Depression: Helping Clients Learn New Skills Coronavirus disease 19 infection, Major depressive disorder Cognitive Behavioral Therapy - Skill enhanced alone, Cognitive behavioral therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ohio State University US 2020-12-11 2023-12-30 2020B0354, NCT04673513 Phase Not Applicable Recruiting 1 36 Months 150 Daniel R Strunk, PhD, Robert J Zhou, Samuel T Murphy 2020-12-25
C-FORWARD: Community Collaboration to Combat COVID-19 Coronavirus disease 19 infection Community-based, mobile van testing alone, Fixed site standard of care testing alone, Self-collected, home-based testing alone Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Johns Hopkins University National Institute of Allergy and Infectious Diseases US 2021-01-31 2021-07-31 C-FORWARD, IRB00250298, NCT04673292, P30AI094189-09S1 Phase Not Applicable Not yet recruiting 1 6 Months 3000 Jacky Jennings, PhD, MPH, Jason E Farley, PhD, MPH, NP, Shruti H Mehta, PhD, MPH 2020-12-24
Physical Rehabilitation of COVID-19 Survivors by Heat Therapy Coronavirus disease 19 infection heat therapy alone Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Massachusetts, Amherst (US) 2021-01-31 2023-12-31 2151, NCT04673318 Phase Not Applicable Not yet recruiting 0 35 Months 87 2020-12-24
Phase III, Randomized, Controlled, Open-Label Study of Pegylated Interferon Alfa-2b With SARS-CoV-2 Coronavirus disease 19 infection, Viral pneumonia peginterferon alfa-2b follow-on-biologic, Zydus-Cadila alone, standard of care alone Interferon alpha 2 ligand Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Zydus Cadila Healthcare Ltd, Zydus Research Centre India 2020-12-28 CTRI/2020/12/029855, PEGI.20.005 Versoion 02 Phase 3 Clinical Recruiting 6 250 Dr Balaji More, Dr Divyang Dalwadi, Dr Kevinkumar Kansagra, Dr Koradia Parshottam Govindbhai, Dr Manjunath K, Dr Manoj Kumar Singh, Dr Nikhil Verma, Dr Nischal Yalgi, Dr Vinay Bhomia 2020-12-25
Exploring the role of virtual reality in midwifery education: a prospective study Coronavirus disease 19 infection, Pregnancy disorder virtual reality learning alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University College Dublin Ireland 2020-04-01 2021-03-31 ISRCTN12735607 Phase Not Applicable Recruiting 2 12 Months 40 Prof McAuliffe 2020-12-22
Ventilatory strategies in severe SARS coV 2 and their outcome Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) K S Hegde Medical Academy Nitte University India 2020-12-16 CTRI/2020/12/029815 Phase Not Applicable Not yet recruiting 1 60 Dr Rashmi Soori, Dr Siri Kandavar 2020-12-23
Tele-counseling on perinatal mental health during pandemics Coronavirus disease 19 infection, Psychiatric disorder COVID-19 related information and education alone, aerobic exercise alone, conscious eating technique alone, four-dimensional seated meditation alone, healthy lifestyle maintenance alone, mindfulness therapy alone, muscle relaxation technique alone, personal bounday and limitation expression alone, pleasant and unpleasant life event-based attitude modification alone, positive family relationship encouragement alone, psychological group tele-counseling alone, self care alone, yoga alone Female Kerman University of Medical Sciences Iran 2020-04-20 2020-05-14 IR.KMU.REC.1399.134, IRCT20170611034452N12 Phase Not Applicable Completed 2 60 Atefeh Ahmadi, Sahebeh Dadshahi, Sahebeh dadshahi 2020-12-24
ISO-BK: Impact of the Respiratory Isolation on the Quality of Life in Patients Hospitalized for Tuberculosis or COVID-19 Coronavirus disease 19 infection, Mycobacterium tuberculosis infection, Psychiatric disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris 2020-12-31 2022-01-31 APHP200227, ISO-BK, NCT04677478 Phase Not Applicable Not yet recruiting 0 13 Months 20 Matthieu Resche-Rigon 2020-12-24
B-FAST Schools and Nurseries: German research network 'Applied Surveillance and Testing' - Workpackage schools and Nurseries (COVID-19) Coronavirus disease 19 infection Oropharyngeal swab alone, Saliva sample alone Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Cologne Bundesministerium für Bildung und Forschung Germany 2020-10-18 20-1463_1, 20-1463_2, B-FAST Schools and Nurseries, DRKS00023911 Phase Not Applicable Recruiting 3 7500 Jörg Dötsch, Universitätsklinikum Köln 2020-12-24
A clinical trial of smart ring that generates continuous temperature data to detect COVID-19 Coronavirus disease 19 infection Oura Ring alone Oura Health Oy, UCSF Osher Center for Integrative Medicine Startsmall, US Department of Defense Armed Forces Health Surveillance Center US Phase Not Applicable Status not specified 1 50 Ashley Mason 2020-12-23
Hydroxychloroquine prophylaxis in preventing the severe forms of Covid-19 Coronavirus disease 19 infection hydroxychloroquine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Islamic Azad University Iran 2020-07-04 IR.IAU.PS.REC.1399.003, IRCT20200421047153N1 Phase 3 Clinical No longer recruiting 1 1000 Farshad Hashemian, Termeh Tarjoman 2020-12-23
ROHOCO: Predictive Value of ROTEM Analysis and Standard Coagulation Tests in Hospitalized Patients with COVID-19 Coronavirus disease 19 infection ROTEM analysis alone, ROTEM sigma alone, Standard Coagulation Tests alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitatsklinikum Essen Tem International GmbH Germany, India, Italy, Mexico, Brazil, France, Colombia, Qatar, Portugal, Spain, Saudi Arabia 2020-04-17 20-9242-BO, DRKS00023934, ROHOCO Phase Not Applicable Recruiting 16 500 Daniel Dirkmann 2020-12-24
Effect of Dalcetrapib in Patients With Confirmed Mild to Moderate COVID-19 Coronavirus disease 19 infection, SARS coronavirus infection dalcetrapib alone Cholesterol ester transfer protein inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) DalCor Pharmaceuticals Canada Inc Covance Inc, Montreal Health Innovations Coordinating Center Canada 2020-12-31 2021-03-31 DAL-401, NCT04676867 Phase 2a Clinical Not yet recruiting 1 3 Months 208 David Kallend, Marianne Rufiange 2020-12-24
EPPICC: European Pregnancy and Pediatric Infections Cohort Collaboration: Pediatric Protocol Acquired immune deficiency syndrome, Coronavirus disease 19 infection, HIV infection, Hepatitis B virus infection, Hepatitis C virus infection, Mycobacterium tuberculosis infection ART therapy alone Healthy volunteers accepted, Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) PENTA Foundation Athena Institute, Netherlands, Centre Hospitalier Universitaire Saint Pierre, Centro Hospitalar Lisboa Norte, Centro Hospitalar do Porto, CoRISpe-S cohort of HIV-infected children, CoRISpe-cat cohort of HIV-infected children, German Pediatric and Adolescent HIV Cohort (GEPIC), Greece Cohort, Hospital de Santa Maria, Irkutsk AIDS Centre, Karolinska Institutet, Medical Research Council Clinical Trials Unit (UK), Polish Paediatric Cohort, Programs for HIV Prevention and Treatment (PHPT), Register for HIV infection in children, Republican Hospital of Infectious Diseases, Swiss HIV Cohort Study, The City HIV Centre, Ukraine Paediatric HIV Cohort, Victor Babes Hospital 2013-01-01 2025-01-01 EPPICC, EPPICC, NCT04677842 Phase Not Applicable No longer recruiting 0 144 Months 10000 2020-12-24
Patients with chronic pain prefer maintenance of pain treatment despite COVID-19 pandemic restrictions Coronavirus disease 19 infection, Pain Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Klinikum der Albert-Ludwigs Universitaet Freiburg Germany 2020-06-15 2020-10-30 353/20, DRKS00022110, U1111-1262-4221 Phase Not Applicable Completed 1 4 Months 400 Barbara Kleinmann 2020-12-23
POPCOV2: Population based Cognitive testing in subjects with Sars-Cov-2 Cognitive disorder, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitätklinikum Düsseldorf Germany 2020-12-28 2020-1198, DRKS00023241, POPCOV2 Phase Not Applicable Not yet recruiting 1 2600 Saskia Elben 2020-12-23
Validation of a SARS-CoV-2 (COVID-19) rapid antigen test in the daily routine of general practitioners for the diagnosis of corona infection Acute bronchitis, Ageusia, Coronavirus disease 19 infection, Dysomia, Respiratory distress syndrome, Viral pneumonia rapid SARS-CoV-2 antigen test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Wuerzburg University Hospital Germany 2020-12-16 254/20, DRKS00023822 Phase 3 Clinical Recruiting 2 4600 Jorn Rohde 2020-12-23
VAC4COVID: SARS-CoV-2 vaccination for COVID-19 disease safety study Coronavirus disease 19 infection SARS-CoV-2 Vaccine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Dundee UK 2020-06-22 2025-12-31 IRAS 286051, ISRCTN95881792, VAC4COVID Phase Not Applicable Not yet recruiting 2 66 Months 1000000 Ms Saywood 2020-12-24
The effects of the COVID-19 pandemic on mental health Anxiety disorder, Coronavirus disease 19 infection, Depression Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Grigore T. Popa University of Medicine and Pharmacy Romania 2020-11-29 2020-12-16 ISRCTN14652655, U1111-1262-3753 Phase Not Applicable Completed 1 500 Dr Adorata Coman, Dr Agnes Bacusca, Dr Ana Maria Holicov, Dr Ana Maria Slanina, Dr Antoneta Petroae, Dr Boanca Mihaela, Dr Dana Anton, Dr Elena Popa, Dr Liliana Barbacariu, Dr Mihaela Manole, Dr Monica Ungureanu, Miss Teodora Tetia 2020-12-24
A clincial trial of RUTI fo the treatment of Covid-19 Coronavirus disease 19 infection RUTI alone Archivel Farma SL Argentina Phase Not Applicable Recruiting 1 Waldo Belloso 2020-12-22
A clinical trial to evaluate Ellume COVID-19 home test  Coronavirus disease 19 infection Ellume COVID-19 home test alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ellume Pty Ltd Phase Not Applicable Status not specified 0 198 2020-12-22
Aralast NP With Antiviral Treatment and Standard of Care Versus Antiviral Treatment With Standard of Care in Hospitalized Patients With Pneumonia and COVID-19 Infection Coronavirus disease 19 infection, Viral pneumonia standard of care alone, Aralast plus remdesivir Alpha 1 proteinase inhibitor, COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Blessing Corporate Services Takeda Pharmaceuticals North America Inc US 2021-01-31 CCR-2020-103188, NCT04675086 Phase 3 Clinical Terminated 1 20 Humam Farah, MD, Kimber Stein, RN-BSN, Kimber Steinbeck, RN-BSN 2020-12-24
A trial to evaluate CD5-deleted CAR T cell for the treatment of COVID-19 Coronavirus disease 19 infection CD5-deleted CAR T cell alone Penn Medicine Emerson Collective Investments Llc, Gabrielle's Angel Foundation, Lymphoma Research Foundation, Parker Institute for Cancer Immunotherapy Phase Not Applicable Planned 0 2020-12-21
A case report study to evaluate remdesivir for the treatment of SARS-CoV-2 patient Coronavirus disease 19 infection convalescent plasma alone, remdesivir alone, azithromycin plus hydroxychloroquine COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator University of Cambridge Medical Research Council, NHS Blood & Transplant, Wellcome Trust Phase Not Applicable Status not specified 0 2020-12-21
A Study to Evaluate the Safety and Immunogenicity of Vaccine CVnCoV in Healthy Adults in Germany Coronavirus disease 19 infection, SARS coronavirus infection SARS-CoV-2 mRNA vaccine (COVID-19), CureVac alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) CureVac AG Germany 2020-12-16 2022-04-30 CV-NCOV-005, NCT04674189 Phase 3 Clinical Recruiting 1 16 Months 2520 Stephan Gehring 2020-12-25
A phase II clinical trial of SOR-C13 for the treatment of covid-19 Coronavirus disease 19 infection SOR-C13 alone TRP cation channel V6 inhibitor Soricimed Biopharma Inc Phase 2 Clinical Planned 0 2020-12-21
A phase I/II clinical trial of SARS-CoV-2 RNA Vaccine (ImplaVax, Imperial College of London) in healthy subjects Coronavirus disease 19 infection SARS-CoV-2 RNA Vaccine (ImplaVax, Imperial College of London/Enesi Pharma) alone Enesi Pharma, Imperial College London Phase 1/Phase 2 Clinical Status not specified 0 400 2020-12-21
CORVIS: Community patients at Risk of Viral Infections including SARS-CoV-2 Coronavirus disease 19 infection RESP-301 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Thirty Respiratory Limited UK 2020-12-11 2020-004951-34, CORVIS, RESP301-005 Phase 2 Clinical Recruiting 1 150 2020-12-24
A clincial sub study evaluating the combination of BRII-196 and BRII-198 for the treatment of  volunteers who have been hospitalized with mild to moderate COVID-19 Coronavirus disease 19 infection BRII-196 plus BRII-198 COVID19 Spike glycoprotein inhibitor Brii Biosciences Phase 3 Clinical Planned 0 1150 2020-12-22
Corona-Warn-App: Acceptance, benefits and effectiveness of the CoronaWarn-App (COVID-19 warning app) Coronavirus disease 19 infection German Corona-Warn-App alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Friedrich-Alexander-Universitaet Erlangen-Nuernberg Germany 2020-12-18 467_20B, Corona-Warn-App, DRKS00023685 Phase Not Applicable Not yet recruiting 1 500 André Jefremow 2020-12-22
Effect of Obesity Among COVID-19 Patients in Critical Care Settings Coronavirus disease 19 infection, Obesity Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry, Japanese Ancestry SERVICES INSTITUTE OF MEDICAL SCIENCES Pakistan 2020-11-10 2020-12-10 16021982, NCT04674553 Phase Not Applicable Completed 1 1 Month 100 Mehwish Iftikhar, FCPS (Endo) 2020-12-23
A phase II clinical trail of Ampion for the treatment of covid-19 Coronavirus disease 19 infection Ampion alone Aryl hydrocarbon receptor agonist, Stem cell antigen-1 inhibitor Ampio Pharmaceuticals Inc US, Israel Phase 2 Clinical Status not specified 2 2020-12-21
Utility of Empiric Antibiotics for Non-intubated Novel Coronavirus Diseases 2019 Patients Coronavirus disease 19 infection, Lower respiratory tract infection, Viral pneumonia empiric antibiotic therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institutes of Health Clinical Center US 2020-03-01 2021-02-28 BD022383, NCT04674410 Phase Not Applicable No longer recruiting 1 12 Months 100000 Sameer S Kadri, MD 2020-12-24
A clincial trial of AstraZeneca,s vaccine in combination with Sputnik V's human adenoviral vector type Ad26  Coronavirus disease 19 infection Sputnik V alone COVID19 Spike glycoprotein modulator AstraZeneca plc 2020-12-31 Phase Not Applicable Planned 0 2020-12-22
A clinical trial of inhaled interferon beta (lung disorders/influenza/COVID-19/lower respiratory tract infection), Synairgen foe the treeatment of COVID-19 Coronavirus disease 19 infection inhaled interferon beta (lung disorders/influenza/COVID-19/lower respiratory tract infection), Synairgen alone Interferon beta ligand Synairgen plc US Phase Not Applicable Not yet recruiting 1 2020-12-22
Evaluation of Safety and Tolerability of COR-101 in Hospitalized Patients With Moderate to Severe COVID-19 Coronavirus disease 19 infection COR-101 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Corat Therapeutics GmbH 2021-01-31 2021-04-30 COR-101/001, NCT04674566 Phase 1/Phase 2 Clinical Not yet recruiting 0 3 Months 45 2020-12-22
A phase IIb field study to evaluate the safety and efficacy of PrEP-001 in the treatment of patients with respiratory viral infection (including COVID-19, influenza and the common cold) Common cold, Coronavirus disease 19 infection, Influenza virus infection, Viral respiratory tract infection PrEP-001 alone PrEP Biopharm Limited Phase 2b Clinical Planned 0 2020-12-21
HISTOCOVID: Pathological Findings of Fatal COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia transcutaneous lung biopsy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) CHU De Nantes Agence nationale de la recherche (ANR) France 2020-04-24 2021-04-24 HISTOCOVID, MR_HISTOCOVID, NCT04675281 Phase Not Applicable Recruiting 43 12 Months 100 AISSAOUI Nadia, AIT-OUTFELLA Hafid, ARGAUD Laurent, AUCHABIE Johann, AZOULAY Elie, BADIE Julio, BOYER Alexandre, CANET Emmanuel, CANET Emmanuel, MD PhD, CARREIRA Serge, CHANAREILLE Pierre-Marie, CHELHA Riad, COLIN Gwenhaël, DECAVELE Maxens, DELLAMONICA Jean, DROUX Damien, DUFOUR Nicolas, EHRMANN Stephane, FERRE Alexis, FOUCAULT Camille, GARCON Pierre, GERI Guillaume, HOUTIN Herve, HRAEICH Sami, LEBAS Eddy, LEGAY François, MAIZEL Julien, MERCAT Alain, MOHEBBI AMOLI Abolfazl, MONCHI Mehran, MORIN Jean, MORIN Jean, MD, MOURVILLIERS Bruno, MULLER Grégoire, NICA Alexandru, PENE Frederic, PLANTEFEVE Gaétan, RICHARD Jean-Christophe, SAGAN Christine, MD, SCHNELL David, SIMON Georges, SIRODOT Michel, SOUWEINE Bertrand, SZTRYMF Benjamin, TADIE Jean-Marc, THIERY Guillaume, VIMPERE Damien, ZUBER Benjamin 2020-12-25
CORVETTE-01: Double-blind study in Covid-19 patients with ivermectin Coronavirus disease 19 infection ivermectin alone Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Japan Agency for Medical Research and Development Kitasato Institute Japan 2020-10-08 CORVETTE-01, jRCT2031200120 Phase 2 Clinical Recruiting 1 240 Nonaka Miwa, Yamaoka Kunihiro 2020-12-22
Effectiveness of Covid-19 Screening in Patients Before Surgery Coronavirus disease 19 infection 2019-nCoV real-time PCR test alone Korea University Guro Hospital South Korea 2020-05-20 2020-10-30 2020GR0205, KCT0005634 Phase Not Applicable Completed 1 5 Months 1500 Byung Wook Min, Jihyun Seo 2020-12-22
ADDS: Development of an Amplified DNA Detection System (ADDS) for the Detection of SARS-Cov-2 based on the Thermocycler Output of FDA-approved COVID-19 RT-PCR kits Coronavirus disease 19 infection Amplified DNA Detection System (ADDS) alone Ateneo de Manila University Philippine Council for Health Research and Development Philippines 2020-06-10 2021-06-10 PHRR201209-003080 Phase Not Applicable No longer recruiting 1 12 Months Jeremie De Guzman, Keith J. Moore 2020-12-22
SWIFTeR: SWIFTeR: A focused study to validate a rapid, simple, and efficient COVID19 testing technology Coronavirus disease 19 infection Isothermal amplification techniques alone Ateneo de Manila University Philippine Council for Health Research and Development Philippines 2020-09-28 2021-09-28 PHRR201209-003081, SWIFTeR Phase Not Applicable Recruiting 1 12 Months Jeremie De Guzman, Keith J. Moore, Ricardo Jose S. Guerrero 2020-12-22
Study to Evaluate Safety and Efficacy of Carrimycin for Treatment of Severe Coronavirus Disease 2019 (COVID-19) in Hospitalized Patients Coronavirus disease 19 infection, SARS coronavirus infection bitespiramycin (oral tablet, bacterial infection), Shenyang Tonglian Group/Institute of Medicinal Biotechnology CAMS alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shenyang Tonglian Group Co Ltd 2021-01-14 2021-06-30 NCT04672564, TLKLXG202001 Phase 3 Clinical Not yet recruiting 0 5 Months 300 Henry Wang 2020-12-23
DiAssCo-ICU: Digital Monitoring of the course of disease in COVID-19 via wearable in-ear sensors Coronavirus disease 19 infection Cosinuss in-ear sensor alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Klinikum Grosshadern Der Ludwig-Maximilians-Universitat Germany 2020-12-20 20-0455, DRKS00023917, DiAssCo-ICU Phase Not Applicable Not yet recruiting 1 126 Roman Schniepp 2020-12-22
COVID-19 Neurological Disease: A Prospective Study Coronavirus disease 19 infection, Neurological disease Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The University of Liverpool Christian Medical College, Vellore, India, Fundacao Oswaldo Cruz (Fiocruz), Instituto Autoimune, National Institute of Mental Health and Neuro Sciences, The Encephalitis Society, University College London, University of Malawi College of Medicine UK 2020-12-31 2021-12-31 NCT04672590, UOL001596 Phase Not Applicable Not yet recruiting 1 12 Months 681 Bhagteshwar Singh, MRCP, Tom Solomon, PhD 2020-12-22
A clinical trial to evaluate the sensitivity and specificity of Oxsed RaVid Direct Testing Kit for the diagnosis of COVID-19 Coronavirus disease 19 infection Oxsed RaVid Direct Testing Kit alone Dnafit Life Sciences Ltd UK Phase Not Applicable Completed 1 69 2020-12-22
A clinical trial to evaluate the sensitivity and specificity of Oxsed RaVid Direct Testing Kit for the diagnosis of COVID-19 infection Coronavirus disease 19 infection Oxsed RaVid Direct Testing Kit alone Dnafit Life Sciences Ltd Hong Kong Phase Not Applicable Completed 1 527 2020-12-22
A clinical trial to evaluate the sensitivity and specificity of Oxsed RaVid Direct Testing Kit for the diagnosis of COVID-19 infection Coronavirus disease 19 infection Oxsed RaVid Direct Testing Kit alone Dnafit Life Sciences Ltd UK, China Phase Not Applicable Completed 2 16 2020-12-22
The effect of orange peel and peppermint extract in coronavirus treatment Coronavirus disease 19 infection orange peel and peppermint extract intake alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shahrekord University of Medical Sciences and Health Services Iran 2020-11-25 IR.SKUMS.REC.1399.107, IRCT20110302005952N2 Phase 3 Clinical Recruiting 3 60 Masoud Hafizi Isfahani, Masoud hafizi isfahani, Mehraban Sadeghi, Mohammadali Ghiasi, Reza Imani 2020-12-22
Long-term COVID-19 Immune Response in a Vulnerable Neighbourhood in Argentina Coronavirus disease 19 infection, Dengue virus infection enzyme linked immunosorbent assay alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Italiano de Buenos Aires Hospital de Niños R. Gutierrez de Buenos Aires, Ministerio de Salud de Ciudad Autónoma de Buenos Aires Argentina 2020-12-02 2021-07-01 3545, NCT04673279 Phase Not Applicable Recruiting 1 7 Months 189 Alicia Mistchenko, Phd, Ana Maria Gomez Saldaño, MD MG, Andrea Gamarnick, Phd, Fernan Quiroz, MD MG, Julieta Salto, Lorena Luna, Magdalena Wagner Manslau, Silvana Figar, MD, Silvana Figar, MD MG, Vanina Pagotto, MD MG 2020-12-22
COVIDIABADO: COVID-19 Pandemic Lockdown Effect in Adolescents and Young Adults With Type 1 Diabetes: Positive Results of an Unpreceded Challenge for Telemedicine and Patient Self-management Coronavirus disease 19 infection, Insulin dependent diabetes glucose monitoring alone Adolescents (13-17 yrs), Young Adults (18-44 yrs) Centre Hospitalien Sud Francilien France 2021-01-01 2021-03-31 COVIDIABADO, IDRCB 2020-A02760-39, NCT04669912 Phase Not Applicable Not yet recruiting 1 3 Months 77 Alfred PENFORNIS, MD PhD, Alfred PENFORNIS, MD, PhD, Caroline TOURTE 2020-12-22
COVID-19 Impact on the Lombardy Region's Emergency System Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Istituto di Ricerche Farmacologiche Mario Negri Italy 2020-09-01 2021-07-31 NCT04669925, TSUNAMI Phase Not Applicable No longer recruiting 4 11 Months 10000 Guido Bertolini 2020-12-22
Willingness to receive a vaccination against SARS-CoV-2 (COVID-19) among patients >/= 80 years Coronavirus disease 19 infection Elderly Adults (80 and over) University of Heidelberg Germany 2020-12-17 DRKS00023921, S-924/2020 Phase 4 Clinical Not yet recruiting 4 700 Petra Benzinger 2020-12-22
A Controlled, Phase II/III Study of Adjuvanted Recombinant SARS-CoV-2 Trimeric S-protein Vaccine (SCB-2019) for the Prevention of COVID-19 Coronavirus disease 19 infection AS-03 plus SCB-2019 COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Clover Biopharmaceuticals AUS Pty Ltd Coalition for Epidemic Preparedness Innovations, International Vaccine Institute Australia 2020-12-31 2022-07-31 CLO-SCB-2019-003, NCT04672395 Phase 2/Phase 3 Clinical Not yet recruiting 1 19 Months 34000 Igor Smolenov, MD, PhD, Pilar Rubio, MD, Vincent Mwangi, MD 2020-12-21
Evaluation of Prognostic Modification in COVID-19 Patients in Early Intervention Treatment Coronavirus disease 19 infection Variable regimens including azithromycin , ivermectin , paracetamol , rivaroxaban Chloride channel modulator, Factor Xa antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Coordinacion de Investigacion en Salud Mexico 2020-12-16 2021-02-12 NCT04673214, R-2020-785-176 Phase 3 Clinical Recruiting 1 1 Month 62 ALMA ITALIA GU MARTINEZ, SPECIALIST, ALMA ITALIA GU MARTINEZ, specialist, GILBERTO CR ARTEAGA, SPECIALIST, GILBERTO CR ARTEAGA, specialist 2020-12-23
A clinical trial of BNT-162b2 for the prevention of COVID-19 in immunocompromized patients Coronavirus disease 19 infection BNT-162b2 alone COVID19 Spike glycoprotein modulator BioNTech SE, Pfizer Inc Phase Not Applicable Planned 0 2020-12-22
A clinical trial of BNT-162b2 for the prevention of COVID-19 in children < 12 years Coronavirus disease 19 infection BNT-162b2 alone COVID19 Spike glycoprotein modulator Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) BioNTech SE, Pfizer Inc Phase Not Applicable Planned 0 2020-12-22
A clinical trial of BNT-162b2 for the prevention of COVID-19 in pregnant women Coronavirus disease 19 infection BNT-162b2 alone COVID19 Spike glycoprotein modulator BioNTech SE, Pfizer Inc Phase Not Applicable Planned 0 2020-12-22
CodePRONUT: Prognostic Impact of the Nutritional Status of Individuals Aged >/= 70 Years With SARS-CoV-2 Coronavirus disease 19 infection Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire Dijon France 2020-10-19 2022-01-31 CodePRONUT, NCT04672343, PUTOT AOIC 2020 Phase Not Applicable Recruiting 1 15 Months 300 Alain PUTOT 2020-12-22
GLS-5310 Vaccine for the Prevention of SARS-CoV-2 (COVID-19) Coronavirus disease 19 infection GLS-5310 (GeneOne Life Science Inc) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) GeneOne Life Science Inc South Korea 2020-12-23 2022-12-31 COV2-001, NCT04673149 Phase 1/Phase 2 Clinical Not yet recruiting 1 24 Months 345 Hyojin Lee, M.S., Joel N Maslow, MD. Ph.D., Woo Joo Kim, MD, Ph.D. 2020-12-23
CovIdeDocS: Impact of the Change in Hospital Service of Caregivers During COVID-19 Health Crisis on Operational Strain Coronavirus disease 19 infection online questionnaire alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Direction Centrale du Service de Sante des Armees France 2020-12-31 2021-09-30 2020-COVID19-33, CovIdeDocS, NCT04667962 Phase Not Applicable Not yet recruiting 2 9 Months 302 Céline RAMDANI, MD, PhD, Julien BOUIX 2020-12-21
Comorbidities and Risk Score in COVID-19 Patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Milano-Bicocca Italy 2020-12-31 2021-12-31 COMORBIDITIES, NCT04670094 Phase Not Applicable Not yet recruiting 1 12 Months 2500 Giuseppe Bellelli, Prof., Giuseppe Citerio, Prof., Maria Grazia Valsecchi, Prof., llaria Capua, Prof. 2020-12-22
A clincial trial of VIRALEZE in healthy volunteers Coronavirus disease 19 infection VIRALEZE alone Healthy volunteers accepted Starpharma Holdings Ltd Phase Not Applicable Planned 0 2020-12-22
Role of Hematological Parameters in the Stratification of COVID-19 Disease Severity Coronavirus disease 19 infection Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Fatima Memorial Hospital Pakistan 2020-05-01 2020-07-31 FMHCMD, NCT04670328 Phase Not Applicable Completed 1 3 Months 101 Ayaz Lone, MBBS,FCPS, Sadia Taj 2020-12-21
Evaluation of the Efficacy of High-Doses of Methylprednisolone in SARS-CoV2 (COVID-19) Pneumonia Patients Coronavirus disease 19 infection, Viral pneumonia Variable regimens including dexamethasone , methylprednisolone , oxygen Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Azienda Unita Sanitaria Locale di Reggio Emilia Italy 2020-12-31 2021-06-30 2020-004323-16, NCT04673162, RCT-MP-COVID-19 Phase 3 Clinical Not yet recruiting 1 6 Months 260 Carlo Salvarani, MD, Marco Massari, MD, Massimo Costantini, Massimo Costantini, MD, Nicola Facciolongo, MD 2020-12-24
A clinical study of new aerosol inhalation in the treatment of severe patients with respiratory virus infection Coronavirus disease 19 infection, Pneumonia aerosol inhalation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Shanghai Public Health Clinic Center Shanghai Science and Technology Commission China 2021-01-01 2023-12-31 ChiCTR2000040847 Phase 0 Clinical Not yet recruiting 1 36 Months 20 Weihui Fu 2020-12-21
Durability and extent of protection of SARS-CoV-2 antibodies among patients with COVID-19 Coronavirus disease 19 infection Philippine General Hospital Philippine Council for Health Research and Development Philippines 2021-01-01 2023-01-01 PHRR201214-003199 Phase Not Applicable Not yet recruiting 1 24 Months Carol Stephanie C. Tan-Lim, MD, Carol Tan-Lim, Elenore Uy, Eva Maria Cutiongco-de la Paz, MD, Leonila F. Dans, MD, MSc, Ma. Liza Antoinette M. Gonzales, MD, Maria Vanessa Villaruz-Sulit, Marissa M. Alejandria, MD 2020-12-22
Nasal Poly-ICLC (Hiltonol) for Prophylaxis of COVID-19 in Healthy Adults Coronavirus disease 19 infection Poly-ICLC alone Interferon agonist, TLR-3 agonist Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Oncovir Inc University of Calgary Canada 2021-01-15 2024-01-16 NCT04672291, ONV2020-003 Phase 1b Clinical Not yet recruiting 1 36 Months 43 Andres M Salazar, MD, Richard Bhardwaj, MBChB, PhD 2020-12-23
Remdesivir and Convalescent Plasma Therapy for Treatment of COVID-19 Infection in Nepal: A Registry Study Coronavirus disease 19 infection, Respiratory failure convalescent plasma therapy plus remdesivir COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Nepal Health Research Council Nepal 2020-11-19 2021-11-19 749-2020, NCT04669990 Phase Not Applicable Recruiting 4 12 Months 2000 Dr. Pradip Gyanwali,MD, Janak Koirala, MD,MPH, Krishna Pokhrel, MD, Rajan Pandey, MD, Saroj Bhattarai, M.Sc, Sher B Kamar, MD, Uday N Singh, MD 2020-12-22
MicrobioCOVID: Role of the Microbiota in the Evolution of the SARS-CoV-2 Disease, COVID-19, in Hospitalized Patients Bacterial infection, Coronavirus disease 19 infection, Viral pneumonia bioinformatic analysis alone, metagenomic sequencing alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-12-04 2022-03-31 APHP201083, MicrobioCOVID, NCT04669938 Phase Not Applicable Recruiting 1 15 Months 200 Etienne Ruppé, Xavier Lescure, xavier lescure 2020-12-21
SourceCOVID: Spread Analysis of COVID-19 Outbreak in France by Self-assessment Web-application Coronavirus disease 19 infection web-application alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Weprom Kelindi France 2021-01-31 2021-03-31 NCT04670003, SourceCOVID, WP-2020-05 Phase Not Applicable Not yet recruiting 1 2 Months 20000 Fabrice DENIS, MD, Magali BALAVOINE 2020-12-21
A preliminary, multicentre, real-world study to evaluate the clinical impact of fondaparinux versus enoxaparin on venous thromboembolism prophylaxis among hospitalized COVID-19 patients Coronavirus disease 19 infection, Deep vein thrombosis fondaparinux sodium alone Factor Xa antagonist University of Campania Luigi Vanvitelli Phase 4 Clinical Status not specified 0 2020-12-18
Physical Activity, Exercise Capacity and Coronavirus Phobia of Adult Cystic Fibrosis Patients During COVID-19 Pandemic Coronavirus disease 19 infection, Cystic fibrosis, Phobia video conferencing alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hacettepe University Turkey 2020-11-04 2021-11-04 GO 20/794, NCT04673331 Phase Not Applicable Recruiting 1 12 Months 24 Aydan Aslı Aksel, Ebru Damadoğlu, PhD, Merve Fırat, MSc, Naciye Vardar Yağlı, PhD 2020-12-22
A phase II clinical study of AV-001, Vasomume Therapeutics/AnGes for the treatment of patients with moderate-to-severe COVID-19 disease Coronavirus disease 19 infection AV-001, Vasomume Therapeutics/AnGes alone Tek tyrosine kinase receptor stimulator Vasomune Therapeutics Inc Phase 2 Clinical Planned 0 2020-12-18
A phase IIb clinical trial of CM-4620 for the treatment of Coronavirus disease 19 infection Coronavirus disease 19 infection, Inflammatory disease, Pancreatitis, Respiratory failure CM-4620 alone Ca2+ release activated Ca2+ channel 1 inhibitor CalciMedica Inc 2021-03-31 Phase 2b Clinical Planned 0 2020-12-18
Combination therapy of favipiravir, camostat mesilate and inhaled ciclesonide for COVID-19 pneumonia Coronavirus disease 19 infection, Viral pneumonia favipiravir alone, Variable regimens including camostat mesylate , ciclesonide , favipiravir RNA polymerase inhibitor, Serine protease inhibitor, Transmembrane serine protease 2 inhibitor, Trypsin inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) International University Of Health & Welfare Japan Agency for Medical Research and Development, The University of Tokyo Hospital Japan 2020-11-11 2021-09-30 CRB3180020, jRCTs031200196 Phase 2/Phase 3 Clinical Recruiting 1 10 Months 100 Hideaki Yamazawa, Hiroshi Otsu, Jiro Terada, Kenji Tsushima, Maki Kobayashi, Masaru Miyazaki, Taichi Mochizuki, Tetsuo Sato, Tsutomu Yamazaki, Yumi Tanaka 2020-12-21
Silmitasertib (CX-4945) in Patients With Severe Coronavirus Disease 2019 (COVID-19) (CX-4945) Coronavirus disease 19 infection, Lower respiratory tract infection silmitasertib alone, standard of care alone Casein kinase II inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Arizona Senhwa Biosciences Inc US 2020-12-15 2022-12-31 CX4945-AV02-IIT, NCT04668209 Phase 2 Clinical Not yet recruiting 2 24 Months 40 Anna Valencia, MPH, MBEMH, Christian Bime, MD, Marilyn Glassberg, MD, Stephanie Marsh, BS, Stephanie Marsh, BS, CCRC 2020-12-21
Study on Safety and Clinical Efficacy of Azvudine in COVID-19 Patients (SARS-CoV-2 Infected) Coronavirus disease 19 infection azvudine alone Nucleoside reverse transcriptase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) HRH Holdings Limited GALZU INSTITUTE OF RESEARCH, SANTA CASA DE MISERICORDIA DE CAMPOS HOSPITAL (SCMCH), Universidade Estadual Do Norte Fluminense Darcy Ribeiro Brazil 2020-12-31 2021-06-30 IGZ-1, NCT04668235 Phase 3 Clinical Not yet recruiting 1 6 Months 342 Cleber G Silva, MD, MSc, George JM Mota, pharmacist, Paula GA Cabral, MSc, PhD, Renato S Martins, MSc, PhD 2020-12-21
Evaluation of Sedation in COVID-19 ARDS Coronavirus disease 19 infection, Respiratory distress syndrome Intubation alone, Mechanical ventilation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Johann Wolfgang Goethe-Universitat Frankfurt am Main Germany 2020-03-01 2021-01-01 #20-643 -SED II, NCT04667936 Phase Not Applicable Recruiting 1 10 Months 100 Armin N Flinspach, MD, Elisabeth H Adam, MD, Elisabeth H. Adam 2020-12-21
Effect of Liver Injury on Mortality in Coronavirus Disease-2019 Patients Admitted to Intensive Care Unit Coronavirus disease 19 infection, Liver injury liver function test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital Turkey 2020-04-01 2020-12-14 CKKACAR, NCT04669509 Phase Not Applicable Completed 1 8 Months 532 Cem Kıvılcım Kacar 2020-12-21
A clinical study to assess rabeximod for the potential treatment of Covid-19, rheumatoid arthritis and potential other indications Coronavirus disease 19 infection, Rheumatoid arthritis rabeximod alone Cyxone AB US Phase Not Applicable Planned 1 2020-12-17
An observational COVID-19 immune response study Coronavirus disease 19 infection 10x Genomics Inc, Adaptive Biotechnologies Corp, Bloodworks Northwest, Fred Hutchinson Cancer Research Center, Gilead Sciences Inc, Isoplexis Corp, Merck & Co Inc, Metabolon Inc, NanoString, Olink Bioscience, Scisco Genetics Inc, Stanford University Amazon Web Services, Biomedical Advanced Research and Development Authority (BARDA), M.J. Murdock Charitable Trust, National Institutes of Health, Novartis AG, Omeros Corp, Parker Institute for Cancer Immunotherapy, US Department of Defense Sweden Phase Not Applicable Status not specified 1 139 Dr Jason Goldman, Dr Yapeng Su 2020-12-22
IMMUNOMARKCOV: Predictive Immune Biomarkers of COVID-19 Pathogenesis to Influence Therapeutic Management Coronavirus disease 19 infection Blood collection alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire de Toulouse France 2020-05-05 2021-12-31 IMMUNOMARKCOV, NCT04668170, RC31/20/0187 Phase Not Applicable Recruiting 2 19 Months 340 Guillaume Martin-Blondel, MD PhD, Isabelle PELLEGRIN, MD, Pierre DELOBEL, MD PhD, Pierre Delobel, MD PhD, Pierre Delobel, PU-PH 2020-12-21
Stop Covid 2: Fluvoxamine for Early Treatment of Covid-19 (Stop Covid 2) Coronavirus disease 19 infection fluvoxamine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), African Ancestry, European Ancestry, Native American Ancestry Washington University in St Louis COVID-19 Early Treatment Fund US, Canada 2020-12-22 2021-09-30 202011101, NCT04668950, Stop Covid 2 Phase 3 Clinical Recruiting 5 9 Months 1100 Angela Stevens, Eric Lenze, MD 2020-12-25
Presence of antibodies in children and young adults living with at least one SARS-CoV-2 positive person Coronavirus disease 19 infection Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) University of Milano-Bicocca Universita degli Studi di Milano Italy 2020-03-15 2020-08-06 CE15052020, ISRCTN91064601 Phase Not Applicable Completed 2 4 Months 49 Prof Tartaglia 2020-12-19
Consequences of the COVID-19 Lockdown Measures on the CHRU Nancy Pediatric Emergency Services Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) Central Hospital, Nancy, France France 2020-03-18 2020-06-30 2020PI235, NCT04668937 Phase Not Applicable Completed 1 3 Months 11000 BELIN Delphine 2020-12-18
Study to Investigate the Treatment Effect of Colchicine in Patients With COVID-19 Coronavirus disease 19 infection colchicine alone, standard COVID-19 care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ayub Teaching Hospital Universidad De Murcia Pakistan 2020-12-10 2021-07-09 ATH/IRB/COLCHICINE/25.11.2020, NCT04667780 Phase 3 Clinical Recruiting 1 7 Months 102 Dr Umer Farooq, Dr. Zeeshan Haroon, MBBS 2020-12-19
CATCOVID-AIR: Noninvasive Respiratory Support in COVID-19 Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia Noninvasive ventilation treatment alone, continuous positive airway pressure (CPAP) therapy alone, high-flow nasal cannula oxygen therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Vall D'Hebron Barcelona Institute for Global Health Spain 2020-05-22 2021-01-31 CATCOVID-AIR, NCT04668196, PR(AG)265/2020 Phase Not Applicable Recruiting 10 8 Months 300 Ana Cordoba, MD PhD, Antoni Marin Muñiz, MD, Gladis Sabater, MD, Juana Martinez Llorens, Md, PhD, Julia Tarrega, MD, Júlia Sampol, MD, Lourdes Lozano, MD, Manel Lujan, MD PhD, Mercedes Pallero, MD PhD, Oscar Bernadich, MD, Patricia Peñacoba, MD, Sergi Marti, MD PhD 2020-12-20
Moving On Trial: COVID-19 and homelessness Coronavirus disease 19 infection permanent housing alone Cardiff University United Kingdom Research & Innovation UK 2020-08-01 2022-01-06 CPMS 47728, ISRCTN69564614, Moving On Trial Phase Not Applicable Not yet recruiting 2 17 Months 1200 Miss Pell 2020-12-18
COVID-NIV: Noninvasive Ventilation in Moderate-to-severe COVID-19-associated Acute Respiratory Distress-syndrome Coronavirus disease 19 infection, Respiratory distress syndrome Capnography alone, Respiratory monitoring alone, electro impedance tomography alone, respiratory muscles ultrasound alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) IM Sechenov Moscow Medical Academy Russian Federation 2020-10-01 2021-06-30 002-NIV-COVID, COVID-NIV, NCT04667923 Phase Not Applicable Recruiting 1 9 Months 50 Andrey I Yaroshetskiy, MD, PhD, ScD, Mikhail E Politov, MD, PhD, Sergey N Avdeev, MD, PhD, ScD 2020-12-18
CARP: COVID-19 Advanced Respiratory Physiology (CARP) Study Coronavirus disease 19 infection, Respiratory failure NHS Greater Glasgow and Clyde Altair Medical Ltd, Storm ID UK 2020-09-29 2021-09-29 CARP, INGN20RM136, NCT04668313 Phase Not Applicable Recruiting 1 12 Months 150 Chris Carlin, Jacqueline Anderson 2020-12-18
Pandemic-adapted Caries Care Multicenter Case-Series Coronavirus disease 19 infection, Dental caries modified cariescare international management alone Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs) Universidad El Bosque, Bogotá King's College London, University of Leeds, University of Sheffield Portugal, Colombia, Uruguay, Netherlands, US, Argentina, UK, Peru, Dominican Republic, France, Mexico, Russian Federation, Brazil 2020-11-15 2022-03-02 IRB00010617, NCT04666597 Phase Not Applicable Recruiting 21 15 Months 420 Aldo Squassi, PhD, Andrea Cortes, PhD, Andrea Ferreira Zandona, PhD, Angeles Martinez-Mier, PhD, Beatriz Echeverry, Christopher Deery, PhD, Clarisa Bonifacio, PhD, Fabiana Carletto-Körber, Irina Kusmina, PhD, Jesús R Osorio, Johanna Sanjuán, Juan S Lara, PhD, Ketty Ramos, Magdalena Sanmartin, Mariana M Braga, PhD, María DP Cerezo, Michele Muller Bolla, Ninoska Abreu-Placeres, Patricia Castro, Paulo Melo, PhD, Rita Villena, PhD, Stefania Martignon, PhD 2020-12-19
Efficacy and Safety of Ivermectin for Treatment and Prophylaxis of COVID-19 Pandemic Coronavirus disease 19 infection anticoagulation therapy alone, eyes, nose and mouth contact avoidance alone, hand hygiene maintenance alone, ivermectin alone, mask usage alone, personal protective equipment alone, respiratory etiquette alone, self-isolation alone, social distancing measures alone, steroid therapy alone, Variable regimens including acetylcystein , azithromycin , ivermectin , lactoferrin , paracetamol , vitamin C , zinc Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Benha University Egypt 2020-06-08 2020-10-30 NCT04668469, RE96.2020 Phase 2 Clinical Completed 1 4 Months 600 Ahmed G Elgazzar, M.D. 2020-12-21
Study of Coagulation Profile and Role of Heparin-Like Effect in Patients With COVID-19 Blood clotting disorder, Coronavirus disease 19 infection, Respiratory distress syndrome, Sepsis Sonoclot machine alone, whole blood coagulation test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Postgraduate Institute of Medical Education and Research India 2020-08-24 2021-02-01 IEC-04/2020-1641, NCT04668404 Phase Not Applicable Recruiting 1 5 Months 50 KAMAL KAJAL, KAMAL KAJAL, MD, Kamal KAJAL, MD, MADHUMITA PREMKUMAR, DM 2020-12-21
NOVATION-1: Phase III Inhaled Novaferon Study in Hospitalized Patients With Moderate to Severe COVID-19 Coronavirus disease 19 infection Novaferon alone, Standard of Care alone Interferon alpha 2 ligand Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Genova Inc 2021-01-31 2021-08-31 JH-COR-003, NCT04669015, NOVATION-1 Phase 3 Clinical Not yet recruiting 0 7 Months 914 Dimitri Fitsialos 2020-12-19
RESICOV: Hospital Interns Psychological State During the COVID-19 Coronavirus disease 19 infection, Psychiatric disorder Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Montpellier France 2020-12-01 2021-07-30 NCT04669054, RECHMPL20_0665, RESICOV Phase Not Applicable No longer recruiting 1 7 Months 102 Emilie Olie, MD PhD 2020-12-21
Changing Susceptible Body Constitution for COVID-19 Prevention by Chinese Medicine in Hong Kong Residents Coronavirus disease 19 infection Variable regimens including Liu-Wei-Di-Huang (PuraPharm International) , Xiang-Sha-Liu-Jun (PuraPharm International) , Yu-Ping-Feng (PuraPharm International) Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The University of Hong Kong Hong Kong 2020-12-15 2022-11-30 NCT04668222, UW20-480 Phase 1/Phase 2 Clinical Not yet recruiting 1 23 Months 480 Cheng Zhang, Mphil, Van Szeto, Yibin Feng, PhD 2020-12-21
ORACLE: Oral Health, Microbial Burden and COVID-19 Coronavirus disease 19 infection PCR test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Eastman Dental Insitute DermBiont Inc, The University College London Hospitals NHS Trust, The Whittington Hospital NHS Trust, University College London UK 2020-12-13 2021-12-12 283766, EDGE 132868, NCT04668911, ORACLE Phase Not Applicable Not yet recruiting 1 12 Months 150 Francesco D'Aiuto, DMD, PhD, MClinDent, Jeanie Suvan, Prof Francesco D'Aiuto 2020-12-19
A Trial Evaluating the Safety and Effects of an RNA Vaccine ARCT-021 in Healthy Adults Coronavirus disease 19 infection ARCT-021 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Arcturus Therapeutics Inc, PPD Development (S) Pte Ltd Singapore 2020-12-27 2022-04-30 ARCT-021-04, NCT04668339 Phase 2 Clinical Not yet recruiting 1 16 Months 600 Arcturus Therapeutics, Dr Jenny Low 2020-12-22
A 6-month research project to investigate the therapeutic potential of SDC-1801 in severe phase Covid-19 Coronavirus disease 19 infection SDC-1801 alone Jak1 tyrosine kinase inhibitor, Non receptor tyrosine kinase TYK2 antagonist Sareum Holdings plc United Kingdom Research & Innovation Phase Not Applicable Status not specified 0 2020-12-22
DIScOVER: Change in Disability in Activities of Daily Living Over Time Among Adults With Advanced Respiratory Disease During the COVID-19 Pandemic Chronic obstructive pulmonary disease, Coronavirus disease 19 infection, Interstitial lung disease, Metastatic lung cancer, Respiratory disease, Respiratory failure Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kings College Hospital NHS Trust National Institute for Health Research (NIHR) UK 2020-01-01 2021-08-01 DIScOVER, IRAS 271894, ISRCTN14159936 Phase Not Applicable Recruiting 6 19 Months 120 Miss Fettes 2020-12-19
AFTER: Predictors of Recovery and the App-Facilitated Tele-Rehabilitation (AFTER) Program for COVID-19 Survivors Coronavirus disease 19 infection biobehavioral tele-rehabilitation alone, home exercise alone, remote controlled exercise alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Colorado at Denver and Health Sciences Center US 2020-12-15 2021-08-01 20-2415, AFTER, NCT04663945 Phase Not Applicable Not yet recruiting 1 7 Months 45 Jennifer Stevens-Lapsley, MPT, PhD 2020-12-18
Evaluating Dove Confident Me Single Session In Indonesia Coronavirus disease 19 infection Dove confident me Indonesia single session program alone Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs) University of the West of England Bristol Unilever, United Nations International Children's Fund, University of Hawaii, University of Indonesia UK 2021-01-31 2021-04-30 DSEP_UNICEF_INDO, HAS-HSS-18-098, NCT04665557 Phase Not Applicable Not yet recruiting 1 3 Months 2000 Nadia Craddock, EdM 2020-12-19
Phase I clinical trial of an inactivated COVID-19 vaccine (Shifa-Pharmed) in healthy individuals Coronavirus disease 19 infection inactivated COVID-19 vaccine (Shifa Pharmed Industrial Group Co) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Shifa Pharmed Industrial Group Co Iran 2020-12-21 IR.NREC.1399.003, IRCT20201202049567N1 Phase 1 Clinical Recruiting 2 56 Minoo Mohraz, Minoo Mohraz- Mohamadreza Salehi- Payam Tabarsi, Mohammadreza Hosseinpour 2020-12-22
Effect of Interferon beta-1b on COVID-19 patients Coronavirus disease 19 infection interferon beta-1b alone, routine treatment alone Bandare-abbas University of Medical Sciences Iran 2020-10-22 IR.HUMS.REC.1399.259, IRCT20201001048894N1 Phase 2/Phase 3 Clinical No longer recruiting 1 90 Afshin Samiei, Dr.Negahi, Teymour Aghamolaei 2020-12-24
Investigational Performance Evaluation of the Nanomix eLab COVID-19 Rapid Antigen Panel With Samples From COVID-19 Positive and Negative Human Subjects Coronavirus disease 19 infection Nanomix eLab system alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Nanomix Inc US 2020-12-01 2021-03-31 NCT04667442 Phase Not Applicable Recruiting 1 4 Months 60 David Ludvigson, Tina Landess 2020-12-19
Awake Pronation for Covid-19 Treatment Coronavirus disease 19 infection, Respiratory failure oxygenation via Venturi mask alone, prone position alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Azienda Ospedaliera Universitaria di Bologna Policlinico Azienda Unita Sanitaria Locale di Reggio Emilia, Hospital Bolzano, University Hospital, Modena Italy 2020-12-30 2021-07-01 1117/2020/SPER/AOUBO, NCT04667286 Phase Not Applicable Not yet recruiting 1 6 Months 100 stefano nava, stefano nava, MD 2020-12-18
Adapting Anxiety Intervention for Youth With Autism for Rapid Response to COVID-19 Anxiety disorder, Autism, Coronavirus disease 19 infection facing your fears program alone Children (6-12 yrs), Adolescents (13-17 yrs) Holland Bloorview Kids Rehabilitation Hospital Canada 2020-12-04 2021-11-30 0240, NCT04666493 Phase Not Applicable Recruiting 1 11 Months 100 Evdokia Anagnostou, MD, Kristina Hyunjee Lee, M.Ed 2020-12-19
An observational retrospective study on the role of methylprednisolone in preventing disease progression for hospitalized patients with severe COVID-19 Coronavirus disease 19 infection methylprednisolone alone Wuhan University China Phase Not Applicable Status not specified 1 175 2020-12-16
Personal Protective Equipment for the Prevention of SARS-Cov-2 During Neonatal Resuscitation Coronavirus disease 19 infection neonatal resuscitation alone, personal protective equipment alone University Hospital Padova Italy 2021-01-31 2021-03-31 COVID-NEO-RES-01, NCT04666233 Phase Not Applicable Not yet recruiting 1 2 Months 48 Daniele Trevisanuto 2020-12-18
Assessment of psychological outcomes in cancer patients during COVID-19 pandemic Acute stress disorder, Anxiety disorder, Cancer, Coronavirus disease 19 infection, Depression Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tata Memorial Center, Tata Memorial Hospital & Cancer Research Inst India 2020-12-22 CTRI/2020/12/029812 Phase Not Applicable Not yet recruiting 1 500 Dr J P Agarwal 2020-12-18
Evaluating efficacy and safety of goggles with or without inbuilt fan in health care workers inside COVID-ICU Coronavirus disease 19 infection N-95 mask alone, gloves alone, head gear alone, impermeable gown alone, indigenous fan powered goggles alone, shoe cover alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) All India Institute of Medical Sciences India 2020-12-24 CTRI/2020/12/029805 Phase Not Applicable Not yet recruiting 1 30 Dr Navdeep Sokhal 2020-12-18
MoveStrong at Home Arthritis, Cardiovascular disease, Congestive heart failure, Coronavirus disease 19 infection, Diabetes mellitus, Hypertension, Lung disease, Obesity, Osteoporosis, Renal disease, Skin cancer, Stroke Exercise program alone, MoveStrong alone, Nutrition education alone, Physitrack alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Waterloo Canada 2020-10-05 2021-04-01 42206, NCT04663685 Phase Not Applicable Recruiting 1 5 Months 25 Ellen Wang, BSc, Lora Giangregorio, PhD 2020-12-19
O-ACEPOP: Online Culture for Mental Health in People Aged 16 to 24 Anxiety disorder, Coronavirus disease 19 infection, Depression Ashmolean Website alone, Ways of Being online Experience alone Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs) University of Oxford 2020-12-04 2021-03-31 0009275, NCT04663594, O-ACEPOP Phase Not Applicable Not yet recruiting 0 3 Months 400 Evgenia Riga, Rebecca Sheriff, PhD 2020-12-20
COVIAS: Evaluation of SARS-CoV2-specific serum parameters in blood samples of SARS-CoV2-seronegative healthy volunteers, hospitalized SARS-CoV2-patients with acute disease and recovered SARS-CoV2-patients with asymptomatic/mild/severe disease Coronavirus disease 19 infection blood drawing alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Heidelberg ImmunoTherapeutics GmbH Germany 2020-12-20 COVIAS, DRKS00023877, S-719/2020 Phase Not Applicable Not yet recruiting 1 150 Torsten Schaller 2020-12-18
TB TRIAGE+ Accuracy: Diagnostic Accuracy of CAD4TB and C-reactive Protein Assay as Triage Tests for Pulmonary Tuberculosis Coronavirus disease 19 infection, HIV infection, Mycobacterium tuberculosis infection Afinion AS100 analyzer (Alere Afinion) alone, Afinion C-reactive protein assay alone, Alere Determine TB LAM Ag test alone, CAD4COVID software (Delft Imaging System) alone, CAD4TB software version 6 and 7 (Delft Imaging System) alone, CD4 advanced disease test alone, CrAg lateral flow assay alone, SARS-COV-2 antigen rapid diagnostic test alone, SARS-COV-2 real-time PCR alone, Standard Q COVID-19 Ag rapid chromatographic immunoassay alone, Standard Q COVID-19 Ag testing device (SD biosensor) alone, Visitect CD4 advanced disease testing device (Omega Diagnostics) alone, Xpert MTB/RIF Ultra assay alone, Xpert MTB/RIF assay alone, differential white blood cell count test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Swiss Tropical & Public Health Institute Charite University, European and Developing Countries Clinical Trials Partnership, Foundation for Innovative New Diagnostics, Human Sciences Research Council, Institute of Tropical Medicine, Ministry of Health of Lesotho, Radboud University, SolidarMed, University Hospital Basel South Africa, Lesotho 2020-12-31 2022-05-31 NCT04666311, P1685-20A, TB TRIAGE+ Accuracy Phase Not Applicable Not yet recruiting 2 17 Months 1400 Aita Signorell, PhD, Klaus Reither, MD, PhD 2020-12-22
MACH19: Mushroom-based Product for COVID-19 Coronavirus disease 19 infection Fomitopsis officinalis and Trametes versicolor intake alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of California San Diego University of California Irvine, University of California Los Angeles US 2020-12-03 2021-08-01 200633, MACH19, NCT04667247 Phase 1/Phase 2 Clinical Recruiting 2 7 Months 66 Andrew Shubov, MD, Gordon Saxe, MD, Lauray MacElhern, MBA, Tatyana Shekhtman, MS 2020-12-20
Wü-KiTa-CoV: Würzburg Childcare Study during the COVID-19 pandemic: A study into the acceptance of different screening measures for the detection of infections with the novel coronavirus (SARS-CoV-2) in child daycare centers in Würzburg Coronavirus disease 19 infection Nasal swabs alone, Throat swabs alone, saliva samples alone University of Wurzburg Bundesministerium für Bildung und Forschung Germany 2020-10-01 182/20-me, DRKS00023721, Wü-KiTa-CoV, http://doi.org/10.23728/b2share.0ee3419f9ed84d17a048bd5ab18c040a Phase Not Applicable Recruiting 1 1000 Oliver Kurzai, Studiensekretariat Wü-KiTa-CoV 2020-12-19
Changes in Viral Load in COVID-19 After Probiotics Coronavirus disease 19 infection Variable regimens including Bifidobacterium animalis , Bifidobacterium longum , Lactis rhamnosus , Lactobacillus rhamnosus , Vitamin D , seleniumt , zinc Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital de Sagunto Biopolis Sl, Laboratorios Heel España Spain 2020-04-01 2021-02-28 HDESAGUNTO, NCT04666116 Phase Not Applicable Recruiting 1 11 Months 96 Laura Sanchis, Xavier Cortes, Xavier Cortés, xavier cortés 2020-12-20
Oxygen therapy in covid positive patients Coronavirus disease 19 infection, Hypoxia, Respiratory failure high flow nasal oxygen cannula therapy alone, non invasive mechanical ventilatory support therapy alone, non rebreathing oxygen face mask therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sri Venkateswara Institute of Medical Sciences India 2020-12-25 CTRI/2020/12/029803 Phase Not Applicable Not yet recruiting 1 122 Aloka Samantaray, Bhargavi Thota 2020-12-18
REMM-HIIT-ICU-COVID: Remotely Monitored, Mobile Health Supported High Intensity Interval Training for Survivors of COVID-19 Coronavirus disease 19 infection remotely monitored, mhealth supported hgh intensity interval training alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Duke University US 2021-01-01 2023-02-01 NCT04664101, PRO00105798, REMM-HIIT-ICU-COVID Phase Not Applicable Not yet recruiting 1 25 Months 30 Alice Szydlowska, Alicja Szydlowska, Paul Wischmeyer, MD 2020-12-18
Ocular Findings and Viral Persistence in Ocular Fluids in COVID-19 Survivors Coronavirus disease 19 infection chloroquine alone, hydroxychloroquine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Eye Institute National Institutes of Health Clinical Center US 2020-12-29 2023-06-30 000078-EI, 10000078, NCT04665752 Phase Not Applicable Recruiting 1 30 Months 150 Dominic Obiyor, R.N., Hatice N Sen, M.D. 2020-12-25
SWS-COVID-19: Southampton Women's Survey COVID-19 Study Coronavirus disease 19 infection Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) University Of Southampton UK 2020-12-31 2020-12-31 56780, NCT04666285, SWS-COVID-19 Phase Not Applicable Not yet recruiting 1 1000 Keith Godfrey, BM, PhD,FRCP, Sarah Crozier 2020-12-17
Viral Shedding, Symptoms and Exposure of SARS-CoV-2 in Non-hospitalized Children With COVID-19 Coronavirus disease 19 infection reverse transcription-polymerase chain reaction alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) Rigshospitalet Denmark 2020-05-25 2021-06-30 H-20028631-1, NCT04666207 Phase Not Applicable Recruiting 1 13 Months 20 Allan Bybeck Nielsen, Marie-Louise von Linstow, MD, PhD, Ulrikka Nygaard, MD, Ulrikka Nygaard, MD, PhD 2020-12-18
The use of tocilizumab in patients with severe COVID19 pneumonia - a trial to know its efficacy in those on steroids Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure, Viral pneumonia conventional treatment alone, tocilizumab alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Nehru HOSPITAL, Postgraduate Institute of Medical Education and Research India 2020-12-31 CTRI/2020/12/029793 Phase 3 Clinical Not yet recruiting 1 54 Naveen Naik B 2020-12-18
Treatment of COVID-19 sequelae with physical exercises Coronavirus disease 19 infection Breathing exercises alone, bronchial hygiene techniques alone, respiratory rehabilitation alone Conselho Nacional de Desenvolvimento Cientifico e Tecnologico - CNPq, Fundação de Amparo à Pesquisa e a Inovação do Estado de Santa Catarina Brazil 2020-03-11 2021-01-11 38682820.0.0000.0121, 4.377.082, RBR-5p8nzk6, U1111-1261-4925 Phase 1 Clinical Recruiting 1 10 Months 82 Aderbal Silva Aguiar 2020-12-21
Comparison of two drugs for better treatment of covid-19 related lung problems Coronavirus disease 19 infection, Pulmonary fibrosis, Viral pneumonia nintedanib alone CSF-1 antagonist, FGF receptor antagonist, FGF1 receptor antagonist, FGF2 receptor antagonist, FGF3 receptor antagonist, Flt3 tyrosine kinase inhibitor, Lck tyrosine kinase inhibitor, Lyn tyrosine kinase inhibitor, PDGF receptor alpha antagonist, PDGF receptor antagonist, PDGF receptor beta antagonist, Src tyrosine kinase inhibitor, VEGF receptor antagonist, VEGF-1 receptor antagonist, VEGF-2 receptor antagonist, VEGF-3 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) KIIT University, Kalinga Institute of Medical Sciences India 2020-12-16 CTRI/2020/12/029814 Phase 2 Clinical Not yet recruiting 1 30 Deepak Sahoo, Pratima Singh 2020-12-18
Symptom-Based Markers for COVID-19 Transmission Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Iowa US 2020-12-31 2021-04-30 202007450, NCT04665245 Phase Not Applicable Not yet recruiting 1 4 Months 500 Alberto M Segre, PhD, Shelby L Francis, PhD 2020-12-17
Access to Chiropractic Care During the COVID-19 Pandemic Coronavirus disease 19 infection, Pain Chiropractic care alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Real Escorial-Maria Cristina University Center Instituto de Investigación Sanitaria de la Fundacion Jimenez Diaz, The University of Birmingham, Universite du Quebec a Trois-Rivieres Spain 2020-12-14 2021-02-28 COHORTCHIROCOVID19, NCT04666779 Phase Not Applicable Not yet recruiting 1 2 Months 500 Arantxa Ortega de Mues, PhD, Carlos Gevers-Montoro, DC,MSc 2020-12-21
REMED: Effect of Two Different Doses of Dexamethasone in Patients With ARDS and COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome corticosteroid therapy alone, dexamethasone alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Brno Charles University, Faculty Hospital Kralovske Vinohrady, Masaryk Hospital Czech Republic 2021-01-01 2023-03-31 CZECRIN NO. 2020/47, NCT04663555, REMED Phase 4 Clinical Not yet recruiting 1 27 Months 300 Jan Malaska,, Jan Maláska, MD, PhD, EDIC, Jan Stašek, MD, EDIC, Jan Stašek, MD, PhD, EDIC 2020-12-16
COVILUS2: Validation of COVILUS Score in Patients Suspected of COVID-19 Infection in the Emergency Room Coronavirus disease 19 infection SARS-CoV-2 RT-PCR test alone, lung ultrasound alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire D Amiens France 2020-12-10 2021-07-31 COVILUS2, NCT04666064, PI2020-843-0129 Phase Not Applicable Recruiting 1 7 Months 100 Stéphane Bar, Dr, Stéphane Bar, MD 2020-12-16
PERSIA: Inspiratory Effort in COVID-19 Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia non invasive respiratory support alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Modena and Reggio Emilia Italy 2020-03-01 2022-02-01 NCT04666246, PERSIA, UMODENAREGGIO17 Phase Not Applicable Recruiting 1 23 Months 40 Alessandro Marchioni, MD, Roberto Tonelli, MD 2020-12-17
A Study to Assess the Virological Efficacy of REGN-10933 + REGN-10987 Across Different Dose Regimens in Adult Outpatients With SARS-CoV-2 Infection Coronavirus disease 19 infection casirivimab + imdevimab (COVID-19), Regeneron/Roche/Genentech alone COVID19 Spike glycoprotein inhibitor Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Regeneron Pharmaceuticals Inc US 2020-12-15 2021-04-24 NCT04666441, R10933-10987-COV-20145 Phase 2 Clinical Not yet recruiting 3 4 Months 1400 Clinical Trial Management, Clinical Trials Administrator 2020-12-19
Effect of malaria or dengue in COVID-19 patients Coronavirus disease 19 infection, Dengue virus infection, Plasmodium infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) B.Y.L Nair Charitable Hospital India 2020-12-21 CTRI/2020/12/029772 Phase Not Applicable Not yet recruiting 1 200 Dr Niraj Mahajan 2020-12-17
Ibrutinib for the Treatment of Patients With B-Cell Malignancies Who Are Infected With Coronavirus Disease 2019 (COVID-19) Chronic lymphocytic leukemia, Coronavirus disease 19 infection, Lymphoplasmacytic lymphoma, Mantle cell lymphoma, Marginal zone B-cell lymphoma ibrutinib alone Btk tyrosine kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Academic and Community Cancer Research United National Cancer Institute US 2020-12-31 2025-05-01 ACCRU-LY-2001, NCI-2020-11785, NCT04665115, P30CA015083 Phase 2 Clinical Not yet recruiting 1 52 Months 134 ACCRU Operations, Sameer A Parikh, Sameer A. Parikh 2020-12-16
What happens when a patient having connective tissue disease develops COVID-19 infection? Connective tissue disease, Coronavirus disease 19 infection, Interstitial lung disease Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) KIIT University, Kalinga Institute of Medical Sciences India 2020-12-12 CTRI/2020/12/029761 Phase Not Applicable Not yet recruiting 1 30 Pratima Singh 2020-12-17
SARS-CoV-2 Donor-Recipient Immunity Transfer Acute lymphoblastic leukemia, Acute myelogenous leukemia, Chronic lymphocytic leukemia, Chronic myelocytic leukemia, Coronavirus disease 19 infection, Hodgkins disease, Myelodysplastic syndrome, Myelofibrosis, Myeloproliferative disorder, Non-Hodgkin lymphoma biomarker analysis alone, granulocyte-colony stimulating factor plus hematopoietic stem cell transplant Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) City of Hope Medical Center National Cancer Institute US 2020-09-23 2022-09-23 20153, NCI-2020-11156, NCT04666025, P30CA033572 Phase 2 Clinical Recruiting 1 24 Months 36 Monzr M Al Malki, Monzr M. Al Malki 2020-12-17
Retrospective Study of ImmunoFormulation for COVID-19 Coronavirus disease 19 infection Variable regimens including Imuno TF , Miodesin , N-acetylcysteine , SiliciuMax , ascorbic acid , cholecalciferol , ferulic acid , glucosamine sulphate + potassium chloride , resveratrol , selenium yeast , spirulina , zinc orotate Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fagron Iberica S.A.U. Spain 2020-07-02 2020-09-29 IMUNO TF STUDY, NCT04666753 Phase Not Applicable Completed 2 2 Months 40 Hudson Polonini, PhD 2020-12-16
IC-COVID-19: Infection Control for Severe Acute Respiratory Syndrome Coronavirus 2 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) NMC Specialty Hospital United Arab Emirates 2021-01-15 2021-02-28 IC-COVID-19, NCT04665960, NMCSPECIALTYH Phase Not Applicable Not yet recruiting 1 1 Month 40 Prashant Nasa, Prashant Nasa, MD FNB, Sheila Myatra, MD 2020-12-19
Exploratory study of safety and efficacy of functional foods containing 5-aminolevulinic acid phosphate and iron for COVID-19 Coronavirus disease 19 infection 5-aminolevulinic acid phosphate alone, iron alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Neopharma Japan Co, Ltd Japan 2020-10-29 jRCTs071200048 Phase 2 Clinical Recruiting 1 50 Koichi Izumikawa, Takeyuki Tanaka 2020-12-17
Teprenone for preventing aggravation of COVID-19 Coronavirus disease 19 infection teprenone alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Okayama University Hospital Japan 2020-05-20 jRCTs061200002 Phase 2 Clinical Recruiting 1 100 ICHIHARA Eiki 2020-12-17
Specified clinical trial for ECMO system for COVID-19 resipiratory failure Coronavirus disease 19 infection novel extracorporeal membrane oxygenation (ECMO) system alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Japan Agency for Medical Research and Development Japan 2020-09-07 jRCTs052200053 Phase 2 Clinical Recruiting 1 50 Fukushima Norihide 2020-12-16
Prohylaxis with hydroxichloroquine aiming at prevention of COVID-19 for medical care workers Coronavirus disease 19 infection hydroxychloroquine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Public Corp Osaka Japan 2020-09-25 jRCTs051200060 Phase 3 Clinical Not yet recruiting 1 500 Kakeya Hiroshi, Kaneko Akira 2020-12-17
COVID-19 Vaccine and Impact on Fertility Study Coronavirus disease 19 infection, Male infertility COVID19 vaccine alone Healthy volunteers accepted, Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) University of Miami US 2020-12-14 2021-06-14 20201451, NCT04665258 Phase Not Applicable Recruiting 1 6 Months 60 Manuel Molina, MD, Ranjith Ramasamy, MD, manuel molina, md 2020-12-16
Biochem, hemato, covid-19, prognostic marker Coronavirus disease 19 infection Hospital Sungai Buloh Malaysia 2020-12-14 2021-12-14 57002, NMRR-20-2682-57002 Phase Not Applicable Status not specified 6 12 Months Dr Alia Nasriana binti Nasuruddin, Dr Dian Nasriana Nasuruddin, Dr JANNALTUL ADNI BINTI AZMI, Dr Nadiah Binti Mohamed Zainuddin, Dr TING HUONG YEW, Dr Tharmini Ravi, Sharifah Khairul Atikah 2020-12-16
COVID-19 Vaccine Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Selayang Hospital Malaysia 2021-01-01 2021-03-01 57541, NMRR-20-2674-57541 Phase Not Applicable Not yet recruiting 1 2 Months Dr NORLIZA MAT ARIFFIN 2020-12-16
A phase II/III, randomized, double-blind, controlled clinical trial of recombinant bivalent second-generation adenovirus (hAd5) vector-delivered SARS-CoV-2 S + N protein vaccine (subcutaneous, COVID-19), ImmunityBio for the treatment of patients infected with SARS-CoV-2 Coronavirus disease 19 infection recombinant bivalent second-generation adenovirus (hAd5) vector-delivered SARS-CoV-2 S + N protein vaccine (subcutaneous, COVID-19), ImmunityBio alone COVID19 Spike glycoprotein modulator, COVID19 nucleoprotein modulator ImmunityBio Inc 2020-08-31 Phase 2/Phase 3 Clinical Recruiting 0 2020-12-15
Effect of biotin, brewer's yeast and vitamin C supplements in patients with COVID-19 Coronavirus disease 19 infection routine therapy alone, Variable regimens including biotin , brewer's yeast , vitamin C Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Tehran University of Medical Sciences Iran 2020-10-15 IR.TUMS.MEDICINE.REC.1399.574, IRCT20201004048923N1 Phase 3 Clinical Recruiting 1 50 Dr Maliheh Paknejad, ِDr Maliheh Paknejad 2020-12-16
Wide Scale Monitoring for Acute Respiratory Infection Using a Mobile-Based Study Platform Coronavirus disease 19 infection, Influenza virus infection, Respiratory tract infection mobile based platform app (Google Inc) alone, wide scale monitoring alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Boston Children's Hospital Google Inc US 2020-11-04 2021-12-08 NCT04663776, P00036213 Phase Not Applicable Recruiting 1 13 Months 100000 John Brownstein, PhD 2020-12-17
3PU-SSE: Prediction of the Patient Pathway in Emergency Room in an Exceptional Sanitary Situation Coronavirus disease 19 infection 3P-U application alone, hospital bedroom booking alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire D Amiens France 2020-12-04 2021-03-31 3PU-SSE, NCT04665778, PI2020-843-0055 Phase Not Applicable Recruiting 1 3 Months 1516 Emilien Arnaud, MD, Émilien ARNAUD, MD 2020-12-15
The Effect of Diabetes Mellitus on Mortality of Patients With COVID-19 Coronavirus disease 19 infection, Diabetes mellitus, Viral pneumonia Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sisli Etfal Hospital Turkey 2020-03-15 2020-05-15 1559, NCT04663659 Phase Not Applicable Completed 1 2 Months 150 Nermin Balta Basi 2020-12-22
A retrospective study of prevalence of incidental pneumonia consistent with COVID19 infection an 18F-Fcholine (FCH) PET/CT in patients referred for prostate cancer Coronavirus disease 19 infection, Prostate tumor 18F-choline alone, computed tomography alone, positron emission tomography alone Hopital Tenon France Phase Not Applicable Status not specified 1 96 2020-12-15
Mental Health Status Mong Admitted Antepartum and Postpartum Women during the COVID-19 Pandemic at the isolation facility in a Tertiary Hospital Coronavirus disease 19 infection, Psychiatric disorder Southern Philippines Medical Center Philippines 2020-12-17 2021-01-17 PHRR201214-003202 Phase Not Applicable Not yet recruiting 1 1 Month Cherie Anne V. Songcaya 2020-12-17
A Study of Clinical Manifestations of Patients with Pulmonary Abnormalities in 18FDG-PET with COVID-19 Infection Coronavirus disease 19 infection computed tomography alone, fludeoxyglucose (18F) alone, positron emission tomography alone University of Gregorio Maranon Phase Not Applicable Status not specified 0 19 2020-12-15
Dyn3CEA_Nosocor: COVID-19 - SARS-CoV-2 Community Contamination in Children and Adults Coronavirus disease 19 infection Hospices Civils De Lyon 2021-01-01 2021-04-04 69HCL20_1100, Dyn3CEA_Nosocor, NCT04664296 Phase Not Applicable Not yet recruiting 0 3 Months 75 Dominique PLOIN, MD 2020-12-16
PREDICT-ILI: Predicting Severity and Disease Progression in Influenza-like Illness (Including COVID-19) Coronavirus disease 19 infection, Influenza virus infection, Respiratory tract infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Imperial College London UK 2020-12-07 2021-06-30 20SM6170, NCT04664075, PREDICT-ILI Phase Not Applicable Not yet recruiting 1 6 Months 100 Christopher Chiu, PhD, Emma Bergstrom, BSc 2020-12-18
Evaluating Safety, Pharmacokinetics and Clinical Benefit of Silmitasertib (CX-4945) in Subjects With Moderate COVID-19 Coronavirus disease 19 infection, Viral pneumonia best supportive care alone, silmitasertib alone Casein kinase II inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Senhwa Biosciences Inc US, Georgia 2020-12-03 2021-02-11 CX4945 AV01-IIT, NCT04663737 Phase 2 Clinical Recruiting 2 2 Months 20 Bella S.C. Bleza, MPH, Chris P. Recknor, MD, Tina Foreman 2020-12-16
To assess symptoms and quality of life in post COVID patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) GMERS Medical College and Hospital India 2020-12-25 CTRI/2020/12/029755 Phase Not Applicable Not yet recruiting 1 50 Dr Anand K Patel, Dr Khushboo Chahwala 2020-12-16
Mass Triaging of Covid 19 Coronavirus disease 19 infection mass triage technique alone HOSPITAL QUEEN ELIZABETH II Malaysia 2020-12-15 2021-01-15 57593, NMRR-20-2693-57593 Phase Not Applicable Recruiting 1 1 Month Dr Aehtoosham Bin Suleman 2020-12-19
Study of clinical and radiological presentation among COVID-19 hospitalized patients based on COVID swab tests Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sri Ramachandra Institute of Higher Education and Research, Sri Ramachandra University India 2020-12-28 CTRI/2020/12/029754 Phase Not Applicable Not yet recruiting 1 100 Dr SP Thiagarajan, Dr Swathy Moorthy 2020-12-16
Perceived emotional, Perceived stressors, Stress level, Coping strategies, Nurses, COVID 19 Pandemic Acute stress disorder, Coronavirus disease 19 infection Healthy volunteers accepted International Medical University Malaysia 2020-12-15 2021-03-31 57277, NMRR-20-2686-57277 Phase Not Applicable Not yet recruiting 1 3 Months Radha Maniam, THANNEESWARRY A/P PARANJOTHI 2020-12-17
Impact of Covid-19 NPI in Malaysia Coronavirus disease 19 infection Non-pharmaceutical Interventions (NPI) alone Universiti Sains Malaysia Malaysia 2021-01-17 2021-10-31 57292, NMRR-20-2684-57292 Phase Not Applicable Status not specified 1 9 Months Dr MOHD IZRUL ISHAM BIN ROSIDI 2020-12-16
Mental health impact of COVID-19 pandemic on PMNS cohort Coronavirus disease 19 infection, Psychiatric disorder Healthy volunteers accepted, Young Adults (18-44 yrs) KEM Hospital and Research Center India 2020-12-26 CTRI/2020/12/029780 Phase Not Applicable Not yet recruiting 1 370 Rishikesh V Behere 2020-12-16
Nintedanib therapy will improve management in covid 19 fibrosis if given early or not Coronavirus disease 19 infection, Pulmonary fibrosis, Viral pneumonia nintedanib alone CSF-1 antagonist, FGF receptor antagonist, FGF1 receptor antagonist, FGF2 receptor antagonist, FGF3 receptor antagonist, Flt3 tyrosine kinase inhibitor, Lck tyrosine kinase inhibitor, Lyn tyrosine kinase inhibitor, PDGF receptor alpha antagonist, PDGF receptor antagonist, PDGF receptor beta antagonist, Src tyrosine kinase inhibitor, VEGF receptor antagonist, VEGF-1 receptor antagonist, VEGF-2 receptor antagonist, VEGF-3 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) KIIT University, Kalinga Institute of Medical Sciences India 2020-12-14 CTRI/2020/12/029783 Phase 2 Clinical Not yet recruiting 1 30 Pratima Singh 2020-12-16
Establishment of a Indo-US Molecular Biomarker Knowledge Network for COVID-19 Coronavirus disease 19 infection Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Indo-US Science and Technology Forum Amrita Institute of Medical Sciences India 2020-12-23 CTRI/2020/12/029773 Phase Not Applicable Not yet recruiting 1 100 Dr Shantikumar V Nair 2020-12-16
Oral Isotretinoin and Covid-19 Infection Coronavirus disease 19 infection isotretinoin alone Retinoic acid receptor agonist Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs) University of Aberdeen UK 2021-01-15 2021-05-31 1/095/20, NCT04663906 Phase Not Applicable Not yet recruiting 1 4 Months 300 Louise King 2020-12-16
An Approach to Screening for COVID-19 at Vancouver Airport Coronavirus disease 19 infection Panbio COVID-19 Ag Rapid Test Device (Abbott Rapid Diagnostics) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of British Columbia Providence Health & Services, Vancouver Airport Authority, WestJet Airlines Canada 2020-11-23 2021-04-30 H20-03225, NCT04665193 Phase Not Applicable Recruiting 1 5 Months 900 Don Sin, MD, Jonathan D'Cruz, Lynda Lazosky, Marc Romney, MD, Tony Yang, PhD 2020-12-16
Understanding Immunity to the COVID-19 Vaccines Coronavirus disease 19 infection COVID-19 vaccine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Stanford University National Institute of Allergy and Infectious Diseases US 2021-01-31 2023-01-31 5U19AI057229-17, IRB-59566, NCT04664309 Phase Not Applicable Not yet recruiting 1 24 Months 1000 Allie Lee, Kari Nadeau, MD, PhD 2020-12-23
The Outcomes of NRICM101 on SARS-COV-2 (COVID-19) Infection Coronavirus disease 19 infection NRICM101 (National Research Institute of Chinese Medicine) alone Healthy volunteers accepted National Research Institute of Chinese Medicine Taiwan 2020-12-20 2022-12-31 NCT04664049, NRICM101 Phase Not Applicable Not yet recruiting 1 24 Months 51000 Chien-Jung Lin, MD, PhD, Yi-Chang Su, MD, PhD 2020-12-16
BIOMARK-COVID: Description of Immunological, Enzymatic and Metabolic Biomarkers Associated to the Severity of COVID-19 (SARS-CoV-2) and Its Resolution Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire De Poitiers Etablissement D’Hospitalisation France 2020-12-09 2022-07-30 BIOMARK-COVID, BIOMARK-COVID, NCT04664023 Phase Not Applicable Recruiting 1 19 Months 120 Nicolas Lévêque, MD 2020-12-16
Efficacy and Safety of High-dose Vitamin C Combined With Chinese Medicine Against Coronavirus Pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Variable regimens including Baimu Qingre Jiedu , Buzhong Yiqi , Huhuang detoxicity paste , alpha-interferon , arbidol , folic acid , immunoglobulin C , ribavirin , vitamin C , vitamin E Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Xi'an International Medical Center Hospital China 2020-02-06 2021-01-31 NCT04664010, XIANINTERNATIONALMCH_HXJ Phase 2 Clinical No longer recruiting 1 11 Months 60 Guoyu Wang, Hui Gao, Jiayue Shan, Kuiwei Zhang, Lei Shang, Qiang Yi, Rui Wang, Shanjiao Jiang, Shenhao Liu, Xijing He, MD, Xudong Yang, Yali Wang, Yifan Feng, Yongping Liu, Zhijian Cheng 2020-12-16
Evaluation Of The Effect Of Favipiravir On Management Patient With Covid-19 Coronavirus disease 19 infection favipiravir alone RNA polymerase inhibitor Arak University of Medical Sciences and Health Services Iran 2020-11-21 IR.ARAKMU.REC.1399.179, IRCT20201028049175N1 Phase 3 Clinical Recruiting 2 114 Alireza Kamali, Behnam Mahmoudieh, Dr.Alireza Kamali, Hossein Sarmadian, Shamim Valibak 2020-12-17
Effects of COVID-19 on dialysis patients Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidade Federal de Minas Gerais Associação Evangélica Beneficente de Minas Gerais Brazil 2020-05-01 3,991,721, 31017120.9.0000.8787, A06004831697, RBR-63hzd3 Phase Not Applicable Recruiting 1 2270 Gabriel Assis Lopes do Carmo 2020-12-16
A retrospective study to evaluate the effectiveness of remdesivir in patients with COVID-19 under mechanical ventilation in an Italian ICU Coronavirus disease 19 infection remdesivir alone COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Azienda Ospedali Riuniti Marche Nord Italy Phase Not Applicable Status not specified 1 51 2020-12-16
An observational study to evaluate nomacopan in particular COVID-19 patients subgroups Coronavirus disease 19 infection nomacopan alone Complement C5 factor inhibitor, Leukotriene BLT receptor antagonist Akari Therapeutics Plc UK Phase Not Applicable Planned 1 100 2020-12-14
Impact of nanopore platform on rapid diagnosis of COVID-19 in patients with respiratory tract infections Coronavirus disease 19 infection, Respiratory tract infection nanopore testing alone Osaka General Medical Center, Osaka University Japan 2020-12-14 2022-12-31 UMIN000042723 Phase Not Applicable Recruiting 1 24 Months 500 Jumpei Yoshimura, Tomoya Hirose 2020-12-16
An observational study evaluating the susceptibility of coronavirus infections in patients taking calcineurin inhibitors compared to non calcineurin inhibitors treatment patients Coronavirus disease 19 infection cyclosporine alone, tacrolimus alone Calcineurin inhibitor Pulsedata Inc US Phase Not Applicable Status not specified 1 5144 2020-12-14
A case-report study of a COVID-19 patient with rhabdomyolysis Coronavirus disease 19 infection, Renal injury, Rhabdomyolysis hemodialysis alone, sarilumab alone IL-6 receptor antagonist Female, African Ancestry University of Florida College of Medicine Phase Not Applicable Status not specified 0 1 2020-12-14
LIF-nCov-2019: A non-interventional, fully anonymized study for the comparative evaluation of a new direct detection methods for infection with SARS-CoV-2 (COVID-19) in clinical samples Coronavirus disease 19 infection, Respiratory disease RT-PCR alone, laser-induced fluorescence spectrospcopy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Aachen Deutsche Forschungsgemeinschaft (DFG), Deutsches Wollforschungsinstitut an der Rheinisch-Westfalischen Technischen Hochschule Aachen eV, German Federal Ministry of Education and Research Germany 2020-04-08 2020-04-30 DRKS00023821, EK 093/20, LIF-nCov-2019 Phase Not Applicable Completed 1 350 Mathias Hornef, Michael Kleines 2020-12-16
Has COVID-19 pandemic been affecting scientific trials to be done by students of Anesthesia Department? Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Postgraduate Institute of Medical Education and Research India 2020-12-20 CTRI/2020/12/029724 Phase Not Applicable Not yet recruiting 1 91 Gandhi Komal Anil 2020-12-18
A Study to Assess the Effectiveness of CAP Asmo in COVID-19 Positive Patients Coronavirus disease 19 infection Asmo capsule (RPS Biotech Private Limited) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) RPS BIOTECH PVT LTD India 2020-12-15 CTRI/2020/12/029714 Phase 2 Clinical Not yet recruiting 1 100 DR MANOJ RUNGHE 2020-12-18
RES-Q-HR: Reconvalescent plasma/Camostat mesylate early in Sars-CoV-2 Q-PCR positive high risk individuals Coronavirus disease 19 infection, Viral pneumonia camostat mesylate alone, convalescent plasma alone, dexamethasone alone, remdesivir alone COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator, Serine protease inhibitor, Transmembrane serine protease 2 inhibitor, Trypsin inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Heinrich Heine Universitat Dusseldorf German Federal Ministry of Health, German Ministry of Health Germany 2020-12-02 2021-11-30 2020-004695-18, NCT04681430, RES-Q-HR, RES-Q-HR Phase 2 Clinical Recruiting 2 11 Months 1094 Verena Keitel, Univ. Prof. Dr. med., Verena Keitel-Anselmino, Prof.Dr.med. 2020-12-25
Pilot, open-label, monocentric study evaluating safety and clinical effect of application of Normosang in patients with COVID-19 disease Coronavirus disease 19 infection, Respiratory disease heme arginate alone Hemoglobin synthesis stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Thomayerova Teaching Hospital Czech Republic 2020-11-16 2020-004682-39, KFJ-2020-02-NORMOSANG Phase 4 Clinical Recruiting 1 8 Skopek -trial coordinator 2020-12-19
COVIDOM: Longterm Morbidity of SARS-CoV-2 Infection and COVID-19 Disease - Consequences for Health Status and Quality of Life Coronavirus disease 19 infection Observation of different courses of SARS-CoV-2 infection in different phases (acute vs. po alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Charite Universitaetsmedizin Berlin, University Hospital Schleswig-Holstein (UKSH) Deutsche Forschungsgemeinschaft (DFG), German Federal Ministry of Education and Research, Nationales Pandemie Kohorten Netz, Wuerzburg University Hospital Germany 2020-11-16 2030-12-31 COVIDOM, COVIDOM-Protokoll_V01F_2020-10, D 537/20, DRKS00023742, NCT04679584 Phase Not Applicable Recruiting 5 121 Months 2000 Anne Hermes, Prof. Dr., Jens-Peter Reese, Prof. Dr., Krawczak Michael, Prof. Dr., Lieb Wolfgang, Prof. Dr., Lilian Krist, Dr., Peter Heuschmann, Prof. Dr., Stefan Schreiber, Prof. Dr., Stefan Stark, Prof. Dr., Thomas Bahmer, Prof. Dr., Thomas Keil, Prof. Dr. 2020-12-24
The effect of Hyssop and Verbascum herbal tea on clinical symptoms of Covid-19 Coronavirus disease 19 infection Hyssop herbal tea alone, Verbscum herbal tea alone, Variable regimens including Seroflo , ceftriaxone , dexamethasone , doxycycline hyclate , favipiravir , interferon beta-1a follow-on biologic (subcutaneous), CinnaGen , ipratropium bromide , levofloxacin , meropenem , methylprednisolone , salbutamol , tocilizumab Beta 2 adrenoceptor antagonist, DNA gyrase inhibitor, Interferon beta ligand, Muscarinic receptor antagonist, Penicillin binding protein inhibitor, RNA polymerase inhibitor, Topoisomerase IV inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Khomein Medical University Iran 2020-12-21 IR.KHOMEIN.REC.1399.012, IRCT20100130003227N15 Phase 2 Clinical Recruiting 1 50 Ashraf Salehi, Dr Mojtaba Didedar, Hamid Moemeni, Mohammad Taheri 2020-12-23
A Study to Evaluate Clazakizumab in Patients With Life-threatening COVID-19 Infection Coronavirus disease 19 infection, Respiratory distress syndrome clazakizumab alone IL-6 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mayo Clinic Arizona US 2020-12-31 2020-12-31 20-008170, NCT04659772 Phase 2 Clinical Recruiting 1 30 Ayan Sen, MD 2020-12-15
Impact of sugars on patients diagnosed with COVID Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sri Ramachandra Institute of Higher Education and Research India 2021-01-01 CTRI/2020/12/029712 Phase Not Applicable Not yet recruiting 1 1000 Shravanthi Naidu S Woodayagiri, Swathy Moorthy 2020-12-15
Assessment of pulmonary function test in patients recovered from COVID19 infection Coronavirus disease 19 infection, Viral pneumonia spirometry alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) GMERS Medical College and Hospital India 2020-12-21 CTRI/2020/12/029669 Phase Not Applicable Not yet recruiting 1 50 Dr Anand Patel, Dr Richa Udhwani 2020-12-18
NO-Hel: Comparison of a helmet interface for non invasive ventilation versus high flow nasal oxygen therapy in management of corona virus patients Coronavirus disease 19 infection Hamilton C3 ventilator alone, non invasive ventilation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Medical Sciences Patna India 2020-12-15 CTRI/2020/12/029711, NO-Hel Phase Not Applicable Not yet recruiting 1 56 NISHANT SAHAY 2020-12-14
HOM_COVID19: Add-on homeopathic treatment of COVID-19 patients Coronavirus disease 19 infection, Hypoxia, Respiratory distress syndrome, Viral pneumonia homeopathic medicine treatment alone, standard of COVID care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Council for Research in Homeopathy India 2021-01-01 CTRI/2020/12/029668, HOM_COVID19 Phase 2 Clinical Not yet recruiting 1 128 Dr Akash Khobragade, Dr Anil Khurana, Dr Naval Kumar Verma, Harleen Kaur 2020-12-18
Skin problems following the use of personal protective equipment Coronavirus disease 19 infection, Dermatological disease personal protective equipment usage alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kasturba Medical College India 2020-12-15 CTRI/2020/12/029663 Phase Not Applicable Not yet recruiting 1 100 Snigdha N Hegde 2020-12-19
The Status of Parathyroid Hormone Secretion in COVID-19 Patients Coronavirus disease 19 infection biochemical testing alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bezmialem Vakif University Turkey 2020-09-10 2020-12-09 08122020, NCT04662437 Phase Not Applicable Completed 1 3 Months 150 Derya Özalp Çelikçi, Dr, Sabahattin Destek 2020-12-17
AAIM-High: Assess and Adapt to the Impact of COVID-19 on CVD Self-Management and Prevention Care in Adults Living With HIV Coronavirus disease 19 infection, Hypertension EXTRA-CVD nurse-led virtual care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Case Western Reserve University Duke University, Metro Health, Michigan, National Heart Lung and Blood Institute, University Hospitals of Cleveland US 2021-02-28 2022-08-31 03-18-16-S1, AAIM-High, NCT04661813, U01HL142099 Phase Not Applicable Not yet recruiting 3 18 Months 75 Chris T Longenecker, MD, Robin Rentrope, MPH, LSW 2020-12-20
COPPS: COVID-19 Outpatient Pragmatic Platform Study: Master Protocol Coronavirus disease 19 infection acebilustat alone, camostat mesylate alone, standard supportive care alone Leukotriene A4 hydrolase inhibitor, Serine protease inhibitor, Transmembrane serine protease 2 inhibitor, Trypsin inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Stanford University US 2021-01-31 2022-01-31 COPPS, COPPS-MASTER PROTOCOL, NCT04662086 Phase 2 Clinical Not yet recruiting 1 12 Months 240 Chaitan Khosla, PhD, Haley Hedlin, PhD, Manisha Desai, PhD, Upinder Singh, MD, Yvonne Maldonado, MD 2020-12-18
EPAC: Efficacy of Homoeopathic prophylaxis Arsenicum Album against COVID-19 Coronavirus disease 19 infection, Viral pneumonia Arsenicum album alone Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) SRM University Ministry of Ayush India 2020-12-12 CTRI/2020/12/029745, EPAC Phase 2 Clinical Not yet recruiting 1 15000 Dr Alex Joseph, Prof Padma Venkat 2020-12-15
COPPS: COVID-19 Outpatient Pragmatic Platform Study: Camostat Sub-Protocol Coronavirus disease 19 infection camostat mesylate alone, standard supportive care alone Serine protease inhibitor, Transmembrane serine protease 2 inhibitor, Trypsin inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Stanford University US 2021-01-31 2022-01-31 COPPS, COPPS-CAMOSTAT, NCT04662073 Phase 2 Clinical Not yet recruiting 1 12 Months 120 Julie Parsonnet, MD 2020-12-18
Study of a Recombinant Coronavirus-Like Particle COVID-19 Vaccine in Adults (USA) Coronavirus disease 19 infection AS-03 plus MT-2766 TLR-9 agonist Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Medicago Inc 2020-12-11 2022-03-31 CP-PRO-COVLP-021(USA), NCT04662697 Phase 2 Clinical Not yet recruiting 0 15 Months 918 Brian Ward, MD 2020-12-15
COPPS: COVID-19 Outpatient Pragmatic Platform Study (COPPS) - Acebilustat Sub-Protocol Coronavirus disease 19 infection acebilustat alone, standard supportive care alone Leukotriene A4 hydrolase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Stanford University US 2021-01-31 2022-01-31 COPPS, COPPS-ACEBILUSTAT, NCT04662060 Phase 2 Clinical Not yet recruiting 1 12 Months 120 Angela Rogers, MD, Joseph Levitt, MD, MS 2020-12-18
Blood changes in COVID-19 and it is influence Coronavirus disease 19 infection Beckman coulter DSX8 alone, COBAS 6500 alone, Sysmex CS 2400 alone Newborn Infants (up to 5 months) Sri Ramachandra Medical College, Hospital & Research institute India 2020-12-15 CTRI/2020/12/029671 Phase Not Applicable Not yet recruiting 1 800 Dr Febe Renjitha Suman, Dr JAYALAKSHMI B 2020-12-14
MICHELLE: Medically Ill Hospitalized Patients for COVID-19 Thrombosis Extended Prophylaxis With Rivaroxaban Therapy Coronavirus disease 19 infection, Thromboembolism, Viral pneumonia rivaroxaban alone Factor Xa antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Science Valley Research Institute Bayer AG Brazil 2020-10-16 2021-06-30 21589 MICHELLE TRIAL, MICHELLE, NCT04662684 Phase 3 Clinical Recruiting 1 8 Months 320 Eduardo Ramacciotti,, Eduardo Ramacciotti, MD, Ph.D, Eduardo Ramacciotti, MD, PhD, Leandro Agati, PhD 2020-12-21
A retrospective, case series study presenting the significant challenges to kidney transplant recipients with risk for higher mortality due to COVID19 infection Coronavirus disease 19 infection, Kidney transplantation Variable regimens including anakinra , azithromycin , belatacept , cyclosporine , hydroxychloroquine , lisinopril , mycophenolate mofetil , prednisone , ravulizumab , tacrolimus ACE inhibitor, Calcineurin inhibitor, Complement C5 factor inhibitor, Cytotoxic T-lymphocyte protein-4 modulator, IgG receptor FcRn large subunit p51 modulator, Inosine monophosphate dehydrogenase inhibitor, PurH purine biosynthesis protein inhibitor, T cell surface glycoprotein CD28 inhibitor, Type I IL-1 receptor antagonist Allegheny Health Network Phase Not Applicable Status not specified 0 4 2020-12-11
Requirements analysis for a robotic assistive system to support and promote the autonomy of people with neuromuscular diseases Coronavirus disease 19 infection, Neuromuscular disease, Spinal muscular atrophy robotic assistance system alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Charite Universitaetsmedizin Berlin Deutsche Forschungsgemeinschaft (DFG), Evangelische Hochschule Ludwigsburg, German Federal Ministry of Education and Research Germany 2020-09-16 DRKS00022534, EA4/150/20, U1111-1257-2583 Phase Not Applicable Recruiting 2 15 Cornelia Eicher 2020-12-14
Analyzing impact of pre-existing comorbidities on serious adverse outcomes in hospitalised COVID19 patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Max Smart Super Speciality Hospital India 2020-12-21 CTRI/2020/12/029744 Phase Not Applicable Not yet recruiting 1 128 Nandani Gulati 2020-12-14
ReDiCare: Relieving Distressed Caregivers: A Pragmatic Trial Coronavirus disease 19 infection care counseling alone, stepped care model alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Friedrich Schiller University of Jena, Robert Bosch Hospital AOK Baden-Württemberg, Deutsche Forschungsgemeinschaft (DFG), German Federal Ministry of Education and Research Germany 2018-05-15 DRKS00014593, FSV 18/08, ReDiCare Phase 3 Clinical No longer recruiting 1 504 Gabriele Wilz, Klaus Pfeiffer 2020-12-14
Analyzing effect of COVID 19 on mental health of frontline healthcare workers Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Max Smart Super Speciality Hospital India 2020-12-21 CTRI/2020/12/029743 Phase Not Applicable Not yet recruiting 1 246 Nandani Gulati 2020-12-14
A clincial trial of PneumoBlast for the trreatment of covid-19 in Brazil Coronavirus disease 19 infection, Respiratory distress syndrome PneumoBlast alone FibroGenesis R4D Biotech Brazil Phase Not Applicable Planned 1 2020-12-14
A Study to Assess the Safety and Efficacy of CoroQuil-Zn 500 in Comparison to the Standard of Care for the Treatment of Mild to Moderate COVID-19 Coronavirus disease 19 infection CoroQuil-Zn alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Remedium Therapeutics Private Limited India 2020-12-15 CTRI/2020/12/029735 Phase 3 Clinical Not yet recruiting 0 100 Disha Shetty, Dr Sambashiva AC, Mr Mallikarjun Bidari 2020-12-14
ESTC: Phase II trial: evaluation of silymarin for treatment of patients with Covid-19 Coronavirus disease 19 infection Variable regimens including Silymarin , azithromycin , chloroquine/hydroxychloroquine , dexamethasone , vitamin- E , vitamin-C , zinc sulphate Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Jos University Teaching Hospital, University of Jos National Veterinary Research Institute Nigeria 2020-12-20 2021-08-27 ESTC, PACTR202012898601759 Phase 2 Clinical Not yet recruiting 2 8 Months 314 Emmanuel Nnadi, John Aguiyi, Nathan Shehu, Pam Luka, Shwe David, Simeon Omale 2020-12-18
A Clinical Safety Study on AT-100 in Treating Adults With Severe COVID-19 Infection Coronavirus disease 19 infection AT-100, Airway alone Lung surfactant associated protein D modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Airway Therapeutics LLC US 2021-01-31 2021-07-31 AT-100/002, NCT04659122 Phase 1b Clinical Not yet recruiting 1 6 Months 9 Marc O. Salzberg, MD, Neil P. Mills, BS, Paul S. Kingma, MD, PhD, Robert D. Hite, MD 2020-12-14
To Assess CT Chest finding of Post-covid Pneumonia Patient Coronavirus disease 19 infection, Pulmonary fibrosis, Viral pneumonia Chest CT scan alone, pirfenidone alone, prednisolone alone, pirfenidone plus prednisolone PDGF receptor antagonist, TGF beta receptor antagonist, p38 MAP kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) GMERS Medical College and Hospital India 2020-12-25 CTRI/2020/12/029733 Phase Not Applicable Not yet recruiting 0 50 Dr Anand Patel, Dr Nil Patel 2020-12-14
COLUMBIA CARDS: Covid-19 Longitudinal, Multi-ethnic, Bioimaging Assessment of Cardiovascular Sequela Registry Cardiovascular disease, Coronavirus disease 19 infection cardiovascular magnetic resonance imaging alone, gadoterate meglumine, GE healthcare alone, transthoracic echocardiogram analysis alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Columbia University GE Healthcare US 2020-12-31 2022-09-30 AAAT0787, COLUMBIA CARDS, NCT04661657 Phase Not Applicable Not yet recruiting 1 21 Months 18 Andrew J Einstein, MD, PhD, Frankie DeJesus, MS, Kathleen Durkin, MS 2020-12-19
SOUNDS: Surgery and Lung Ultrasound in SARS-CoV-2 Infection Coronavirus disease 19 infection lung ultrasound alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundacion Clinica Valle del Lili Colombia 2020-05-08 2021-11-30 1601, NCT04661631, SOUNDS Phase Not Applicable Recruiting 1 18 Months 451 Alberto F Garcia, MDMSc 2020-12-14
Aerobic Training Versus Cognitive Behavioral Therapy in Management of Anxiety Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression aerobic exercises alone, cognitive behavioral therapy alone Female, Young Adults (18-44 yrs) Cairo University Egypt 2020-12-10 2021-02-25 12-2020, NCT04662021 Phase Not Applicable Recruiting 0 2 Months 40 Marwa Eid 2020-12-15
CLOSER_MS: Offering Support and Electronic Resources for Care Partners of Those With Multiple Sclerosis Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression tele-coaching alone, website based information alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Case Western Reserve University US 2021-01-10 2021-10-31 CLOSER_MS, MS-1610-37015 enhancement, NCT04662008 Phase Not Applicable Not yet recruiting 1 9 Months 150 Amy R Lipson, PhD, Matthew Plow 2020-12-18
Health After Covid-19 in Tyrol Coronavirus disease 19 infection Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Medizinische Universität Innsbruck Claudiana Landesfachhochschule Austria 2020-09-30 2021-12-31 20200928-2379, NCT04661462 Phase Not Applicable Recruiting 0 15 Months 1000 Judith Löffler-Ragg, MD 2020-12-16
A Study of Auxora in Patients With Critical COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia CM-4620 alone Ca2+ release activated Ca2+ channel 1 inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) CalciMedica Inc Northwestern University US 2020-12-31 2021-04-30 CM4620-205, NCT04661540 Phase 2 Clinical Not yet recruiting 1 4 Months 36 Richard Wunderink, MD, Richard Wunderlink, MD, Sudarshan Hebbar 2020-12-14
MONIREA: Use of RDS MultiSense in Post-ICU Patients in the COVID-19 Era Coronavirus disease 19 infection, Viral pneumonia MultiSense strip alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopitaux Universitaires de Strasbourg Rhythm Diagnostics Systems Inc France 2021-06-30 2022-06-30 20-004, MONIREA, NCT04661423 Phase Not Applicable Not yet recruiting 0 12 Months 60 Armelle TAKEDA, PhD, Julien POTTECHER, MD, PhD 2020-12-14
Reward Re-Training: A New Treatment to Address Reward Imbalance During the COVID-19 Pandemic Coronavirus disease 19 infection, Eating disorder reward re-training group therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Drexel University The National Institute of Mental Health US 2020-12-01 2022-03-30 2009008088, NCT04661410, R01MH122392-01S1 Phase Not Applicable Recruiting 1 15 Months 60 Research Coordinator 2020-12-14
MejoraCare_P: MejoraCare-Paraguay: mHealth Solution for Chronic Patients During the COVID-19 Outbreak in Paraguay Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection MejoraCare app alone, Routine care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidad Autónoma de Encarnación Salumedia Labs, University of Valencia Paraguay 2020-12-09 2021-12-09 MejoraCare_P, NCT04659746, PINV 20-9 Phase Not Applicable Not yet recruiting 1 12 Months 96 Carmen Cabral, Matías Denis, Nadia Czeraniuk, Rosa María Baños, PhD 2020-12-15
FENOC: Fenofibrate for Patients With COVID-19 Requiring Hospitalization Coronavirus disease 19 infection fenofibrate (micronized), Fournier/Abbott alone, usual medical care alone Lipoprotein lipase stimulator, PPAR alpha agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hebrew University of Jerusalem Barzilai medical center Israel 2020-12-13 2021-12-01 0105-20-BRZ, FENOC, NCT04661930 Phase 3 Clinical Recruiting 0 11 Months 50 Avner Ehrlich, Mahram Nassar, MD, Shlomo Mayaan, MD, Yaakov Nahmias, PhD 2020-12-14
COVEPICARDIO: The Cognitive and sport Virtual EPIC Training Study for Cardiovascular Diseases Atherosclerosis, Atrial fibrillation, Coronavirus disease 19 infection, Diastolic heart failure, Systolic heart failure home-based cognitive training alone, physical exercise training alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Montreal Heart Institute Canada 2020-05-18 2022-12-01 COVEPICARDIO, ICM 2020-2785, NCT04661189 Phase Not Applicable Recruiting 0 30 Months 118 Florent Besnier, PhD, Louis Bherer, PhD 2020-12-15
A Study to Assess the Effectiveness of ImmuRich in COVID-19 Positive Patients Coronavirus disease 19 infection ImmuRich capsule (RPS Biotech Private Limited) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) RPS BIOTECH PVT LTD India 2020-12-15 CTRI/2020/12/029713 Phase 2 Clinical Not yet recruiting 0 100 DR MANOJ RUNGHE 2020-12-14
Koa Family Study: A Community-Based Intervention to Improve Health and Well-Being (KFS) Coronavirus disease 19 infection, Obesity Whole health program alone, health messages texting alone, mind-body-spirit intervention alone, social media support alone, tree planting alone Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) University of California Davis US 2021-01-31 2021-09-30 1668154, Koa Family Study, NCT04662593 Phase Not Applicable Not yet recruiting 1 8 Months 120 Crystie Dao, MS, Desiree Backman, DrPH, MS, RD, Neal Kohatsu, MD, MPH 2020-12-14
CAPNOR: Impact of Molecular Testing on Improved Diagnosis, Treatment and Management of CAP Coronavirus disease 19 infection, Pneumonia BioFire FilmArray Pneumonia plus platform (Biomerieux) alone, active feedback alone, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry alone, microbiological biochemical testing alone, real-time PCR alone, ultra-rapid molecular testing alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Haukeland University Hospital Copenhagen University, Drammen Hospital, Quadram Institute Bioscience, Rigshospitalet, Universitair Medisch Centrum Utrecht, University Of Southampton, University of Bergen Norway 2020-09-25 2022-12-31 CAPNOR, HAUKELANDUH_31935, NCT04660084 Phase Not Applicable Recruiting 1 27 Months 1060 Elling Ulvestad, MD PhD, Harleen Grewal, MD PhD, Rune Bjørneklett, MD PhD 2020-12-14
ASCO: ASCO Survey on COVID-19 in Oncology Registry Cancer, Coronavirus disease 19 infection American Society of Clinical Oncology US 2020-04-19 2022-12-31 ASCO, NCT04659135, PRO00014181 Phase Not Applicable Recruiting 63 32 Months 2000 Adam Al Douri, Alexander Spira, Amol Rao, Angie Dunbar, Anthony Franklin, Ashley Jones, Brandon Bennett, Brenda Groff, Charu Aggarwal, Christopher Laman, Christopher McNair, Christy Hughes, Danielle Geiger, Dara Richie, Debbie Vidlak, Elizabeth Garrett-Mayer, PhD, Eric Clayton, Eric Small, Gina Cravey, Hailey Johnson, Ihab Azab, Jamie Harper, Jen H Williams, MA, Jennifer Orlando, Karen Sceniak, Kathryn Mileham, Kelly Hattery, Kent Disney, Kevin Mills, Kimberly Maher, Latha Subramanian, Lisa Kosmacek, Lori Backus, Lynn Harrison, Mandy Joosten, Margaret Mazzone, Mary Amos, Matthew Carter, Matthew Korzeniewski, Melanie Meehan, Michelle Britto, Milan Sheth, Nancy Studier, Nicole Fowler, Peter Yu, Philip Lammers, Poornima Saha, R. Donald Harvey, PharmD, Richard L Schilsky, MD, Rosie Drulias, Rudi Ross, Sandra Guy, Scott Baker, Stephanie McClellan, Suanna S Bruinooge, MPH, Susan Knight, Susan Moore, Tara Barker, Thomas Semrad, Thorvardur Halfdanarson, Tina Inverso, Uzma Rizwan, Wasif Saif, Williams Wood 2020-12-14
Phase I Study to Evaluate Safety and Pharmacokinetics of COVID-HIGIV Administered as a Single Dose or a Repeat Dose in Healthy Adults Coronavirus disease 19 infection COVID-HIG alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Emergent BioSolutions Inc US Department of Defense US 2020-12-31 2021-09-30 EBS-CVH-003, NCT04661839 Phase 1 Clinical Recruiting 1 9 Months 56 Clinical Trial Manager 2020-12-18
Adolescents With COVID-19/MIS-C at HCFMUSP Coronavirus disease 19 infection home-based exercise training program alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) University of Sao Paulo Fundacao de Amparo a Pesquisa do Estado Sao Paulo, Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo Brazil 2020-09-24 2021-04-30 37460620.8.0000.0068, NCT04659486 Phase Not Applicable Recruiting 0 7 Months 100 Bruno Gualano, Clovis Silva, PhD 2020-12-24
Phase I/II Randomized, Dose Escalation Study to Evaluate the Safety and Antiviral Activity of the RD-X19 Device in SARS-CoV-2 Infected Individuals With Uncomplicated COVID-19 Coronavirus disease 19 infection RD-X19 alone, electromagnetic treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) EmitBio Inc. KNOW Bio LLC US 2020-11-18 2021-04-30 EB-P12-01, NCT04662671 Phase 1/Phase 2 Clinical Recruiting 2 5 Months 60 EB-P12-01 Study Director 2020-12-14
ACP-COVID: Advance Care Planning: Communicating With Outpatients for Vital Informed Decision Coronavirus disease 19 infection ACP Decisions Video Program alone, VitalTalk communication skills training alone, intervention training alone, medical record review alone Healthy volunteers accepted, Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dana-Farber Cancer Institute Inc National Institute on Aging US 2020-12-15 2021-05-14 20-600, ACP-COVID, NCT04660422, UH3AG060626-03S1 Phase Not Applicable Recruiting 1 5 Months 13150 Edith Burns, MD, James A. Tulsky, MD 2020-12-17
NOSOCOVID: Nosocomial COVID-19 in ICU Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) CHU De Nantes France 2020-09-01 2021-03-01 MR_NOSOCOVID, NCT04659356, NOSOCOVID Phase Not Applicable Recruiting 0 6 Months 600 BOURIGAULT Celine, MD, CANET Emmanuel, PHd, GARRET Charlotte, GARRET Charlotte, MD, LASCARROU Jean-Baptiste, MD, LEMARIE Jeremy, MD, MARTIN Maelle, MD, REIGNIER Jean, PHd 2020-12-14
Tele-RehaB: Pulmonary Tele-Rehabilitation Program: Feasibility and Safety Study Coronavirus disease 19 infection, Respiratory disease pulmonary telerehabilitation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec Fondation IUCPQ Canada 2020-12-31 2022-01-31 21983, NCT04658979, Tele-RehaB Phase Not Applicable Recruiting 0 13 Months 30 Didier Saey, Ph.D, Didier Saey, PhD, Jany Harvey, M.Sc. 2020-12-14
Factors Affecting Mortality in Critical Patients Admitted to Intensive Care Unit Due to COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital Turkey 2020-03-22 2020-12-08 NCT04659876, SEPTEMBER 11, 2020: 550 Phase Not Applicable Completed 0 8 Months 445 Osman Uzundere 2020-12-21
Combination therapy trial in COVID-19 patients Coronavirus disease 19 infection antibiotic treatment alone, anticoagulant treatment alone, antiviral treatment alone, sitagliptin alone, spironolactone alone, supplement intake alone, Variable regimens including dexamethasone , sitagliptin , spironolactone Aldosterone antagonist, Dipeptidyl peptidase IV inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Boushehr University of Medical Sciences Iran 2020-12-05 IR.BPUMS.REC.1399.140, IRCT20201003048904N2 Phase 2 Clinical Recruiting 0 200 Farhad Abbasi, Farzan Azodi, Gholamreza Khamisipour 2020-12-14
Cancer Within a Pandemic: A Telemental Health Intervention Anxiety disorder, Cancer, Coronavirus disease 19 infection, Depression online support group test alone, questionnaires alone, telemental health session alone Young Adults (18-44 yrs) Wake Forest University Health Sciences, US National Cancer Institute US 2021-02-28 2021-07-31 IRB00070150, NCT04659993, P30CA012197, WFBCCC01520 Phase Not Applicable Not yet recruiting 1 5 Months 15 Katie Duckworth, Ph.D, Katie Duckworth, PhD, Study Coordinator 2020-12-15
The mechanism of COVID-19 associated coagulopathy: a prospective, cohort study Blood clotting disorder, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tohoku University Japan Agency for Medical Research and Development Japan 2020-11-09 UMIN000042717 Phase Not Applicable Recruiting 0 100 Koji Saito, Yudai Iwasaki 2020-12-21
COVID-19 (coronavirus Disease 2019) Coronavirus disease 19 infection, Psychiatric disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) HOSPITAL LAHAD DATU Malaysia 2020-12-14 2021-01-14 57156, NMRR-20-2655-57156 Phase Not Applicable Status not specified 1 1 Month 300 Dr WONG YEN SHEN 2020-12-17
COVID-19 Infection among Healthcare Workers Coronavirus disease 19 infection Ministry of Health, Malaysia Malaysia 2020-12-14 2021-03-13 57584, NMRR-20-2648-57584 Phase Not Applicable Status not specified 0 3 Months Dr Abdul Aziz Harith 2020-12-14
COVID-19 pandemic and breast cancer management: An observational clinical study from Pakistan Breast tumor, Coronavirus disease 19 infection breast cancer surgery alone, neoadjuvant/systemic chemotherapy alone, telecommunication alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Aga khan University Aga Khan University Hospital karachi Pakistan 2020-03-14 2020-10-03 2020-5418-14043, DRKS00023807 Phase Not Applicable Completed 0 6 Months 112 Dua Jabeen, Narmeen Asif 2020-12-14
TRISSR: Impact of The New Triage System and Structural Reorganization of Emergency Department on Health Care Worker Exposed to Suspected Covid-19 Patients - A Single Center Analysis Coronavirus disease 19 infection Healthy volunteers accepted Hospital Kuala Lumpur Malaysia 2020-12-05 2021-01-27 57197, NMRR-20-2636-57197, TRISSR Phase Not Applicable No longer recruiting 1 1 Month Dr Mahathar Abdul Wahab, SUFIAN BIN SAFAAI 2020-12-15
Spanish Survey on Third Wave of COVID-19 Coronavirus disease 19 infection Healthy volunteers accepted Universidad De Salamanca Spain 2020-12-09 2020-12-20 COVIDSAL01/2020, NCT04659473 Phase Not Applicable Not yet recruiting 0 1000 Beatriz M Bermejo-Gil, Professor, Fátima Pérez-Robledo, Doctor, Fátima Pérez-Robledo, Professor, Inés Llamas-Ramos, Doctor, Inés Llamas-Ramos, Professor, Juan L Sánchez-González, Professor, Rocío Llamas-Ramos, Professor 2020-12-15
A randomized, double-blind, placebo-controlled Phase II Clinical Trial to evaluate the safety and efficacy of a combination treatment of two drugs, and the best supportive care for patients with moderate and severe COVID-19 in a hospitalized setting Coronavirus disease 19 infection combination of two drugs alone Venn Life Sciences Phase 2 Clinical Status not specified 0 200 2020-12-11
ProBCG: Use of BCG Vaccine as a Preventive Measure for COVID-19 in Health Care Workers Coronavirus disease 19 infection BCG vaccine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidade Federal do Rio de Janeiro Ministry of Science and Technology, Brazil Brazil 2020-10-01 2022-10-01 31942220.8.1001.5257, NCT04659941, ProBCG Phase 2 Clinical Recruiting 1 24 Months 1000 Fernanda CQ Mello, PhD, Fernanda Carvalho de Q Mello, PhD, JOSE ROBERTO LAPA E SILVA 2020-12-17
Evaluation of Aerosol in a Dental Clinic Coronavirus disease 19 infection external evacuation device alone, extraoral vacuum aspirator alone, high volume evacuation suction device alone, hydrogen peroxide alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Texas Health Science Center Houston US 2020-12-01 2022-12-01 HSC-DB-20-1017, NCT04659928 Phase 4 Clinical Not yet recruiting 1 24 Months 50 Aaron Glick, DDS, FAGD, FICOI, D.ABDSM 2020-12-14
CORONADO: Circulating Tumor Protein Quantification Capillary Blood COVID Coronavirus disease 19 infection, Multiple myeloma, Plasma cell dyscrasia at-home blood sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institute of Cancer Research UK The Royal Marsden NHS Trust UK 2021-01-15 2021-10-01 CCR5361, CORONADO, NCT04659252 Phase Not Applicable Not yet recruiting 0 8 Months 70 Chloe Burrows, Haemato-oncology Research Team, Kevin Boyd 2020-12-14
Stress situation survey for hospital staff related to the new coronavirus Acute stress disorder, Coronavirus disease 19 infection Audio slides alone, brief pamphlet alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Nagasaki University Japan 2020-12-14 UMIN000042689 Phase Not Applicable Not yet recruiting 1 800 Hirohisa Kinoshita 2020-12-17
A trial to evaluate Covid-19 vaccine for the prevention of Covid-19 Coronavirus disease 19 infection Covid-19 vaccine, VLP Therapeutics LLC alone VLP Therapeutics LLC National Center For Global Health & Medicine, National Institute of Biomedical Innovation, Oita University, Osaka City University Japan Phase Not Applicable Planned 0 2020-12-10
RIC as an Adjunct Therapy for Severe COVID-19 Disease: a Prospective, Randomized, Pilot Study Coronavirus disease 19 infection, Ischemia, Viral pneumonia remote ischemic conditioning alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) St Michaels Hospital Canadian Department of National Defence Canada 2020-12-15 2021-09-01 1.4, NCT04659460 Phase Not Applicable Not yet recruiting 0 8 Months 30 Sandy Trpcic 2020-12-15
Thyroid Function Tests and Status of Thyroid Autoantibodies in Covid-19 Patients Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bezmialem Vakif University Turkey 2020-09-01 2020-12-07 06122020, NCT04659200 Phase Not Applicable Recruiting 0 3 Months 20 Aysegul Yabacı, Research, Didem Ertorul, Dr, Sabahattin Destek, Sabahattin Destek, Associate Professor 2020-12-15
Hyperpolarized 129-Xe MRI of Survivors of COVID-19 Coronavirus disease 19 infection 129-Xe MRI alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Kansas Medical Center US 2021-01-01 2021-12-31 00146646, NCT04659707 Phase 1 Clinical Not yet recruiting 1 12 Months 20 Peter J Niedbalski, PhD, Peter J. Niedbalski 2020-12-21
A first global investigator-initiated phase-2 clinical trial in Mexico for camostat mesilate being developed as COVID-19 treatment Coronavirus disease 19 infection repurposed camostat mesilate (oral, COVID-19), Daewoong/Institut Pasteur Korea/Korea Institute of Radiological and Medical Sciences alone Serine protease inhibitor, Transmembrane serine protease 2 inhibitor, Trypsin inhibitor Daewoong Pharmaceutical Co Ltd, Institut Pasteur Korea, Instituto Nacional de Ciencias Medicas y Nutricion, Korea Institute of Radiological and Medical Sciences Mexico 2020-12-09 Phase 2 Clinical Status not specified 0 2020-12-10
Study Evaluating Safety, Tolerability and Efficacy of Allocetra-OTS in Patients With COVID-19 Coronavirus disease 19 infection Allocetra alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Enlivex Therapeutics Ltd 2021-03-31 2022-03-31 ENX-CL-03-001, NCT04659304 Phase 1b Clinical Not yet recruiting 0 12 Months 50 Lior Binder, Odelia Ben Shitrit, MBA, Oren Hershkovitz, PhD 2020-12-11
A trial to evaluate Soberana 01 for the prevention of COVID-19 Coronavirus disease 19 infection FINLAY-FR-1 alone Finlay Institute Cuba Phase Not Applicable Not yet recruiting 1 2020-12-22
An observational study to evaluate the impact of COVID-19 on children with cystic fibrosis Coronavirus disease 19 infection, Cystic fibrosis Cystic Fibrosis Foundation Phase Not Applicable Status not specified 0 105 2020-12-10
Remdesivir plus Tocilizumab efficacy trial in moderate to severe COVID-19 patients Coronavirus disease 19 infection remdesivir plus tocilizumab COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Medical College Kolkata India 2020-12-15 CTRI/2020/12/029615 Phase 2 Clinical Not yet recruiting 1 60 Dr Swati Datta 2020-12-16
Clinical Assessment of Insulin Fast Dissolving Film in Treatment of Post Infection Anosmia Coronavirus disease 19 infection, Dysomia insulin alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Deraya University Minia University Egypt 2020-12-01 2021-01-15 NCT04657809, S85INSU23FDF Phase 2 Clinical No longer recruiting 0 1 Month 40 Soad Ali, Soad Mohamed 2020-12-11
ASPEN-COVID-19: Assessing Safety, Hospitalization and Efficacy of rNAPc2 in COVID-19 Blood clotting disorder, Coronavirus disease 19 infection AB-201, Arca Biopharma alone Factor VII antagonist, Tissue factor inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) ARCA Biopharma Inc Colorado Prevention Center, University of Colorado US 2020-12-10 2021-05-31 ASPEN-COVID-19, NAPc-201/301, NCT04655586 Phase 2/Phase 3 Clinical Recruiting 3 5 Months 100 Dr Michael Bristow, Jennifer Meriwether, Marc Bonaca, MD, MPH 2020-12-19
The Effect of Omega-3 Supplements on the Serum Levels of ACE/ACE2 Ratio as a Potential Key in Cardiovascular Disease and COVID-19: A Randomized Clinical Trial in the COVID-19 Uninfected Jordanian People Cardiovascular disease, Coronavirus disease 19 infection omega-3 fatty acids alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Applied Science Private University Jordan 2020-12-05 2021-03-30 2020-PHA-22, NCT04658433 Phase Not Applicable Recruiting 0 3 Months 100 Luai z Hasoun, PhD, Mahmoud S Abu-Samak, PhD, Mahmoud Suleiman Abu-Samak, Sara M Daboul, MSC, Sara M Daboul, Master, luai z Hasoun, PhD 2020-12-11
OXYCOVID: Liberal use of oxygen in early stage of COVID-19 patients Coronavirus disease 19 infection oxygen alone, usual care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) AIIMS Jodhpur India 2020-12-16 CTRI/2020/12/029614, OXYCOVID Phase 2 Clinical Not yet recruiting 0 80 Dr Mahendra Kumar Garg 2020-12-14
GARDEN: Glenzocimab in SARS-Cov-2 Acute Respiratory Distress Syndrome Related to COVID-19 Coronavirus disease 19 infection, Dyspnea, Respiratory distress syndrome glenzocimab alone Platelet glycoprotein VI inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Acticor Biotech France, Brazil 2020-12-22 2021-07-31 2020-002733-15, ACT-CS-006, GARDEN, NCT04659109 Phase 2 Clinical Recruiting 2 7 Months 60 Andrea Comenducci, MD, Professor Julien POTTECHER, Professor Victor A. Hamamoto SATO, Yannick Pletan, MD 2020-12-24
Drug to prevent lung injury secondary to COVID 19 Acute lung injury, Coronavirus disease 19 infection Heparin alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute Of Medical Sciences, Rishikesh India 2020-12-14 CTRI/2020/12/029613 Phase 2 Clinical Not yet recruiting 1 30 Bhavna Gupta 2020-12-20
CORONA Germany: Clinical Outcome and Risk in Hospitalized COVID-19 Patients: An Epidemiological Study From Germany Arterial thrombosis, Cancer, Cardiac arrest, Cardiac failure, Cardiogenic shock, Coronary artery disease, Coronavirus disease 19 infection, Heart arrhythmia, Ischemic stroke, Lung embolism, Myocardial infarction, Myocarditis, Phlebothrombosis Asklepios Proresearch Asklepios Kliniken Hamburg GmbH Germany 2020-03-26 2021-07-01 #3871, CORONA Germany, NCT04659187 Phase Not Applicable Recruiting 0 15 Months 4000 Axel Stang, Prof. MD, Bertholt Bein, Prof. MD, Christian Glöckner, MD, Christoph U Herborn, Prof. MD, Dirk Arnold, Prof. MD, Hans-Peter Hauber, MD, Jürgen Behr, Prof. MD, Klaus Herrlinger, Prof. MD, Lorenz Nowak, MD, Martin Bergmann, Prof. MD, Melanie Gunawardene, MD, Nele Gessler, MD, Rüdiger Schreiber, MD, Sebastian Wirtz, MD, Stephan Willems, Prof. MD, Thomas Hölting, MD, Tino Schnitgerhans, MD, Ulrich-Frank Pape, MD 2020-12-20
A study on efficacy of combined Chinese and Western medicine and follow-up of long-term prognosis in patients with novel coronavirus pneumonia (COVID-19) Carbohydrate metabolism disorder, Cardiovascular disease, Cerebrovascular disease, Coronavirus disease 19 infection, Renal disease, Respiratory disease, Viral pneumonia different treatment regimens (combined Chinese and Western medicine) alone Public Health Clinical Center of Chengdu China 2021-01-10 2021-05-30 ChiCTR2000040770, ChiMCTR2000004148 Phase Not Applicable Recruiting 0 4 Months 300 Chen Qing, Wu Guihui 2020-12-11
Clinical and Hematological Phenotypes in Long COVID Coronavirus disease 19 infection, Inflammatory disease peripheral blood immunophenotyping alone, serum biochemistry analysis alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) HCA International UK 2020-12-31 2021-06-30 LCV, NCT04659889 Phase Not Applicable Recruiting 0 6 Months 100 Dr Paul Glynne, Mr Glynne, Dr, Natasha Tahmasebi, Miss, Paul Glynne, Dr, Rajeev Gupta, Dr, Vanya Gant, Dr 2020-12-14
A Phase 1/2 randomized, placebo-controlled, multi-centre study to evaluate the safety and immunogenicity of a novel Receptor Binding Domain (RBD) COVID-19 Vaccine in Healthy Adults Coronavirus disease 19 infection RBD SARS-CoV-2 HBsAg VLP (CpG 1018 (150 mcg) or Alum ) alone, RBD dose plus Alum alone, RBD dose with Alum adjuvant plus CpG 1018 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) ACCELAGEN PTY LTD, Serum Institute of India Privated Ltd Australia 2020-12-09 ACTRN12620001308987 Phase 1/Phase 2 Clinical Not yet recruiting 2 255 Mr Greg Plunkett, Prof Terry Nolan 2020-12-16
Optimized TCM diagnosis and treatment plan for novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Traditional Chinese Medicine alone, conventional treatment alone, integrated Chinese and conventional medicine alone Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Beijing Hospital of Traditional Chinese Medicine affiliated to Capital Medical University Beijing science and Technology Commission China 2020-12-01 2021-01-31 ChiCTR2000040765, ChiMCTR2000004147 Phase Not Applicable Recruiting 0 2 Months 700 Liu Qingquan, Su Rui 2020-12-11
A survey of the impact on mental health and therapies in patients with chronic disease during the pandemic of COVID-19 Anxiety disorder, Coronavirus disease 19 infection, Depression Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The First Affiliated Hospital of college of medicine Zhejiang University China 2020-10-10 ChiCTR2000040729 Phase Not Applicable Recruiting 0 800 Minglan Wu 2020-12-11
FACE COVID-19: Femoral Fractures and COVID-19 Coronavirus disease 19 infection, Lower limb fracture Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Istituto Ortopedico Galeazzi Spa Italy 2020-11-14 2020-12-31 FACE COVID-19, FACE COVID-19, NCT04657510 Phase Not Applicable Recruiting 0 1 Month 140 Francesca Villa, MSc, Francesco Luceri, MD, Giuseppe M Peretti, MD, Ilaria Morelli, MD, Riccardo Giorgino, MD 2020-12-11
TBA: Pulmonary and fitness characteristics of COVID-19 patients with persistent dyspnea and / or reduced exercise capacity Coronavirus disease 19 infection, Dyspnea pulmonary function tests alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Onze Lieve Vrouwe Gasthuis Amsterdam Netherlands 2020-06-01 2021-12-31 NL9093, TBA, WO 20.148 Phase Not Applicable Recruiting 1 19 Months 100 Tom Wiggers 2020-12-17
COVID-PRICE: COVID-19 Pregnancy Related Immunological, Clinical and Epidemiological Factors and Perinatal Outcomes Coronavirus disease 19 infection Female Thomas Jefferson University The Nemours Foundation US 2020-11-17 2022-06-30 20F.1043, COVID-PRICE, NCT04659759 Phase Not Applicable Recruiting 1 19 Months 50 Rupsa C Boelig, MD 2020-12-11
Effectiveness of internet psychotherapy in reduction of anxiety/depression of infertile women Anxiety disorder, Coronavirus disease 19 infection, Depression online cognitive behavioral therapy alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) National Institute for Medical Research Development Iran 2020-12-05 IR.NIMAD.REC.1398.174, IRCT20110228005931N9 Phase Not Applicable Recruiting 0 60 Dr. Farzan Kheirkhah, Dr. Farzan Kheyrkhah, Dr. Zahra Basirat, mahboobe faramarzi, shiva shafie rizi 2020-12-11
Expanded Access to Zofin (Organicell Flow) for Patients With COVID-19 Coronavirus disease 19 infection Zofin (Organicell Flow) alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Organicell Regenerative Medicine bioRASI LLC 19881-EA, NCT04657406 Phase Not Applicable Recruiting 0 Mari Mitrani, MD, PhD 2020-12-14
Expanded Access Protocol on Bone Marrow Mesenchymal Stem Cell Derived Extracellular Vesicle Infusion Treatment for Patients With COVID-19 Associated ARDS Adult respiratory distress syndrome, Coronavirus disease 19 infection, Hypoxia, Respiratory failure ExoFlo alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Direct Biologics LLC DB-EAP-001, NCT04657458 Phase Not Applicable Recruiting 0 Heidi Moran 2020-12-11
A Study of FOY-305 in Patients With SARS-Cov-2 Infection (COVID-19) Coronavirus disease 19 infection camostat mesylate alone Serine protease inhibitor, Transmembrane serine protease 2 inhibitor, Trypsin inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ono Pharmaceutical Co Ltd Japan 2020-11-09 2021-05-31 FOY305-01, NCT04657497 Phase 3 Clinical Recruiting 0 6 Months 110 Naoyuki Komura 2020-12-11
COFATSOM: Fatigue and Sleep in Patients With COVID-19 Coronavirus disease 19 infection, Fatigue Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) University Hospital, Bordeaux 2020-12-05 2021-06-30 CHUBX 2020/52, COFATSOM, NCT04657419 Phase Not Applicable Not yet recruiting 0 6 Months 720 Pierre PHILIP, Pr 2020-12-15
COVIDTEL: Parental Compliance After Telephone Triage Advice During and After Confinement During the COVID Epidemic in France Coronavirus disease 19 infection formalized telephone triage advice alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) Fondation Lenval France 2020-12-31 2021-03-31 20-HPNCL-03, COVIDTEL, NCT04656444 Phase Not Applicable Not yet recruiting 0 3 Months 250 Antoine TRAN, Antoine TRAN, MD 2020-12-11
The Impact of COVID-19 on Surgical Practice in Jordan During the Second Outbreak: A Survey Coronavirus disease 19 infection Healthy volunteers accepted Yarmouk University Jordan 2020-11-01 2020-11-10 ChiCTR2000040633 Phase Not Applicable No longer recruiting 0 60 Raed M Ennab 2020-12-11
UNITED: At-Home Infusion Using Bamlanivimab in Participants With Mild to Moderate COVID-19 Coronavirus disease 19 infection bamlanivimab alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Aged Adults (65-79 yrs), Elderly Adults (80 and over) UnitedHealth Group Inc Eli Lilly & Co, Optum Inc US 2020-12-31 2021-05-31 2020-0081_, NCT04639479, NCT04656691, UNITED Phase 4 Clinical Not yet recruiting 1 5 Months 7500 Dan Griffin, MD, PHD, Michelle Tanner, BA, Tracy Ziolek, MS 2020-12-11
Effect Of Covid-19 Disease In Smell And Taste Of Patients With Mild, Moderate Or Severe Symptomatology Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Ioannina General Hospital of Ioannina G. Hatzikosta Greece 2020-11-17 2021-06-30 931/17-11-2020, NCT04657445 Phase Not Applicable Recruiting 1 7 Months 100 AIKATERINI LIANOU, SPECIALIST, ANGELOS LIONTOS, CONSULTANT, ATHINA ZARACHI, SPECIALIST, CHARALAMPOS MILIONIS, PROFESSOR, ELEFTHERIOS KLOURAS, RESIDENT, IOANNIS KASTANIOUDAKIS, PROFESSOR, IOANNIS KOMNOS, CONSULTANT, Liontos Angelos, MARIA MICHALI, SPECIALIST, ORESTIS MILIONIS, MED. DOCTOR 2020-12-22
COVIDVacImpac: Impact of the COVID-19 Pandemic on Vaccination Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Montpellier France 2020-11-01 2021-05-30 COVIDVacImpac, NCT04657263, RECHMPL20_0655 Phase Not Applicable Recruiting 2 6 Months 500 Ariane Sultan, Ariane Sultan, MD, Cyril BREUKER, Cyril BREUKER, PharmD,Phd, cyril BREUKER 2020-12-14
A phase III trial to evaluate CoviSafe for the detection of COVID-19 Coronavirus disease 19 infection CoviSafe alone Kannaba Technologies Inc Therma Bright Inc Phase 3 Clinical Planned 0 2020-12-10
A phase II trial to evaluate CoviSafe for the detection of COVID-19 Coronavirus disease 19 infection CoviSafe alone Kannaba Technologies Inc Therma Bright Inc Phase 2 Clinical Planned 0 2020-12-11
A phase I trial to evaluate CoviSafe for the detection of COVID-19 Coronavirus disease 19 infection CoviSafe alone Kannaba Technologies Inc, Therma Bright Inc Phase 1 Clinical Planned 0 2020-12-11
Brief Mindfulness-Based Intervention to Improve Psychological Wellbeing Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Psychiatric disorder virtual brief mindfulness session alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Imam Abdulrahman Bin Faisal University Saudi Arabia 2020-07-07 2020-09-05 MINDFULLNESS during COVID19, Mindfullness during a pandemic, NCT04656626 Phase Not Applicable Completed 0 1 Month 146 Amani al-qurni, BOARD 2020-12-14
Disinfection & cross infection tests on sports equipment in covid-19 Coronavirus disease 19 infection a cross-infection test alone, disinfectants alone, test gloves alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) St Marianna University School of Medicine Japan 2020-10-28 UMIN000042270 Phase Not Applicable Not yet recruiting 0 41 Hiroto Fujiya, Kanaka Yatabe 2020-12-10
NgT-NAFOGA(NATION) Study: Phase I clinical trial to investigate the safety, tolerability and pharmacokinetics of NewGenNafamostat in healthy male subjects Coronavirus disease 19 infection nafamostat (COVID-19 infection), Institut Pasteur Korea alone Serine protease inhibitor, Transmembrane serine protease 2 inhibitor Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) NewGen Therapeutics Inc NewGen Therapeutics Inc South Korea 2020-12-05 KCT0005647, NgT-NAFOGA(NATION), NgT-NAFOGA(NATION) Study Phase 1 Clinical Not yet recruiting 0 32 Hyun Chul Kim, Seung Hwan Lee 2020-12-10
MORPH-II: Revisiting A Mobile Intervention to Reduce Pain and Improve Health Coronavirus disease 19 infection, Pain caloric restriction intervention alone, movement restriction intervention alone Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Wake Forest University US 2021-01-31 2022-10-31 IRB00023965, MORPH-II, NCT04655001 Phase Not Applicable Not yet recruiting 1 21 Months 100 Amber Brooks, MD, Charlotte Crotts, BS, Jason Fanning, PhD 2020-12-10
DIRECTOR: Dynamics of the Immune Response to COVID-19/Infection by SARS-CoV-2 Coronavirus disease 19 infection, Respiratory tract infection Healthy volunteers accepted, Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitat des Saarlandes MeMed Diagnostics Ltd Germany 2020-12-02 2021-11-30 109/20, DIRECTOR, NCT04655521 Phase Not Applicable Recruiting 0 11 Months 300 Cihan Papan, MD 2020-12-19
Urine Alkalinization to Prevent AKI in COVID-19 Coronavirus disease 19 infection, Renal injury sodium bicarbonate alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Guy's & St Thomas' Hospital NHS Trust UK 2021-02-01 2022-03-30 283852, NCT04655716 Phase 3 Clinical Not yet recruiting 0 13 Months 80 Marlies Ostermann 2020-12-11
Hospitalization or Outpatient Management of Patients With SRAS-CoV-2 Infection - Revised HOME-CoV Score Study Coronavirus disease 19 infection revised HOME-CoV score alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Angers France 2020-12-08 2021-06-08 2020-A03067-32, NCT04657471 Phase Not Applicable Recruiting 28 6 Months 1300 Alexandre GHUYSEN, Andrea PENALOZA, Anyhony CHAUVIN, Caroline SOULIE, Christian BRICE, Coralie CAYEUX, David DALL'ACQUA, Delphine DOUILLET, Emmanuel MONTASSIER, Esma OUMMAMAR, Florent FREMY, Francis COUTURAUD, Frédéric BALEN, Henri Hani KARAM, Henrinjatovo ANDRIANJAFY, Julie PERNET, Kasarra BEN HAMMOUDA, Laure ABENSUR VUILLAUME, Marc ANDRONIKOF, Marc NOIZET, Mathieu VIOLEAU, Medhi TAALBA, Meïssa KARE, Mustapha SEBBANE, Nicolas PESCHANSKI, Ombeline SUSONG, Pascal BISSOLOKELE, Pierre-Clément THIEBAUD, Romain BLONDET, SCHMIDT Jeannot, Sonja CURAC, Stéphane GENNAI, Séverine GOSSELIN, Yann-Erick CLAESSENS 2020-12-21
Multiple Interactive With Nutrition and Exercise Strategies in Frailty Cancer Patients Coronavirus disease 19 infection, Muscle weakness cycle exercise alone, online nutrition consultation alone, routine nutrition consultation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tzu Chi University Taiwan 2020-11-01 2023-11-30 NCT04654637, TCU-CHHUANG Phase Not Applicable Recruiting 0 37 Months 128 Chu Hou Huang, PhD, Chun Hou Huang, Chun Hou Huang, Phd 2020-12-10
SARS-CoV-2/COVID-19 Prevalence Study Coronavirus disease 19 infection Healthy volunteers accepted, Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) COVID-19 Prevention Network US, Puerto Rico 2020-12-15 2021-03-30 COVPN 5002, NCT04658121 Phase Not Applicable Not yet recruiting 14 3 Months 3920 Ayana Moore, PhD, Jessica Justman, MD, Laura Mkumba 2020-12-10
Impact of Postoperative Telemedicine Visit versus In-person Visit on Patient Satisfaction During the COVID-19 Pandemic: A Prospective, Randomized Trial Coronavirus disease 19 infection Telemedicine visit alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cedars-Sinai Medical Center US 2020-09-28 2021-06-30 NCT04652674, STUDY00000944 Phase Not Applicable Recruiting 1 9 Months 70 Karen Zaghiyan, MD, Lucille Yao, MD, Phillip Fleshner, MD 2020-12-10
COLDSTER: Comparison of Two Corticosteroid Regimens for Post-COVID-19 Diffuse Lung Disease Coronavirus disease 19 infection, Lung disease, Viral pneumonia prednisolone alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Postgraduate Institute of Medical Education and Research India 2020-12-08 2021-12-07 COLDSTER, INT/IEC/2020/SPL-1528, NCT04657484 Phase 2 Clinical Recruiting 0 12 Months 100 Ritesh Agarwal, MD, DM, Sahajal Dhooria, Sahajal Dhooria, MD, DM 2020-12-23
Edtech-HPV: A Community Approach Using Education and Technology to Increase HPV Vaccination Coronavirus disease 19 infection, Papillomavirus infection Text messaging reminder alone, parental HPV vaccine education alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Memorial Sloan-Kettering Cancer Center US 2017-06-28 2022-06-30 17-336, Edtech-HPV, NCT03209713 Phase Not Applicable Recruiting 4 60 Months 800 Abraham Aragones, MD, MS, Ester Corpuz, Eva Moya, PhD, Francesca Gany, MD, MS, Rebeca Aceves Zaragoza 2020-12-10
A clinical trial of peginterferon alfa-2b follow-on-biologic, Zydus-Cadila for the treatment of Coronavirus disease 19 infection Coronavirus disease 19 infection Zydus Cadila Healthcare Ltd US Phase Not Applicable Planned 1 2020-12-09
Reducing Food Insecurity During COVID-19 Coronavirus disease 19 infection Fresh Connect produce prescription program alone, grocery store gift cards alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Boston Medical Center Corp Krupp Family Foundation, Patient Centered Outcome Research Institute, US Department of Agriculture, Waldron Charitable Fund US 2021-01-31 2022-10-31 6007145, H-41052, NCT04652596, PENDING Phase Not Applicable Not yet recruiting 1 21 Months 250 Erin Ashe, MPH, Jocelyn Antonio, BS, Michael Silverstein, MD MPH, Michael Silverstein, MD, MPH 2020-12-09
STOP: Preference-based Tools for Smoking Cessation Among Disadvantaged Smokers, a Pragmatic, Randomized, Controlled Trial Coronavirus disease 19 infection, Nicotine dependence STOP smoking cessation intervention alone, drug prescription alone, e-liquid alone, electronic cigarette alone, free smoking aid delivery alone, nicotine alone, nicotine replacement therapy alone, routine care alone, short didactic video watching alone, smoking cessation advice alone Nicotinic acetylcholine receptor agonist Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Société de Formation Thérapeutique du Généraliste INSERM, National Cancer Institute, France France 2020-12-15 2023-12-15 NCT04654585, STOP, STOP-001 Phase 2 Clinical Not yet recruiting 0 36 Months 528 André Nguyen Van Nhieu, MD, André Soares, MD, Anne Kerharo-Nicolas, MD, Anne-Laurence Le Faou, MD, Anne-Marie Ruppert, MD, Boyer Laurent, MD, Carole Plaussu, MD, Cécile Roche Dominguez, MD, Fabienne El-Khoury, Fabienne El-Khoury Lesueur, PhD, Ghislaine Hacke Mela, MD, Gladys Ibanez, MD, Kebir Oussama, MD, Kinouani Shérazade, MD, Laura Piras, MD, Maria Melchior, PhD, Marion Adler, MD, Mathilde Roze, MD, Michel Cadart, MD 2020-12-15
PRINCESS: Pronation in COVID-19 Patients Undergoing Non Invasive Respiratory Support Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia awake prone position alone, non invasive respiratory support alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Modena and Reggio Emilia Italy 2020-03-01 2020-11-30 NCT04649658, PRINCESS, UMODENAREGGIO10 Phase Not Applicable Completed 0 9 Months 93 Roberto Tonelli 2020-12-16
COVID-RIC1: Seroprevalence Study of CoV-2-SARS (COVID-19) Infection in Patients With Chronic Inflammatory Rheumatic Diseases Coronavirus disease 19 infection, Psoriatic arthritis, Rheumatoid arthritis, Spondylarthritis routine care alone, serological testing alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Montpellier France 2020-12-01 2021-07-30 COVID-RIC1, NCT04655612, RECHMPL20_0624 Phase Not Applicable Recruiting 0 7 Months 5000 Jacques MOREL, MD, PhD, Jacques Morel, MD, PhD, Thao Pham, MD, PhD 2020-12-15
Impact of COVID-19 Pandemic on Out-of-Pocket Costs, Lost Wages, and Unemployment in Patients With Breast Cancer Undergoing Breast Surgery Breast tumor, Coronavirus disease 19 infection mastectomy alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) MD Anderson Cancer Center National Cancer Institute US 2019-05-21 2022-03-31 NCI-2019-07463, NCT04169542, PA18-1077 Phase Not Applicable Recruiting 4 34 Months 600 Anaeze Offodile, Elizabeth FitzSullivan, Makesha V. Miggins, Richard A. Ehlers 2020-12-10
Cov-activity: Physical Activity Program Implementation in Hospitalized Positive Covid-19 Older Adults Coronavirus disease 19 infection physical activity program alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire de Toulouse France 2020-11-01 2021-12-31 Cov-activity, NCT04647682, RC31/20/0145 Phase Not Applicable Recruiting 0 14 Months 30 Laurine ANDRE, MD 2020-12-10
SPUTNIK-UAE: A Phase III Clinical Trial of the Immunogenicity and Safety of the Gam-COVID-Vac Vaccine Against COVID-19 in the UAE Coronavirus disease 19 infection Sputnik V alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gamalei Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation Collaborator PDC-CRO Saudi Arabia, United Arab Emirates 2020-12-31 2021-12-31 06-GAM-COVID-VAC-2020, NCT04656613, SPUTNIK-UAE Phase 3 Clinical Recruiting 0 12 Months 1000 Ahmed Al Hammadi, Mohamed Mostafa 2020-12-23
Addressing Anxiety in 2 to 3-Year Olds: A Pilot, Intervention Study Anxiety disorder, Coronavirus disease 19 infection, Generalized anxiety disorder, Phobia, Social phobia being brave protocol based-cognitive behavioral therapy alone Healthy volunteers accepted, Infants (6-23 months), Preschool Children (2-5 yrs) Massachusetts General Hospital US 2019-09-27 2022-09-01 2018P000376, NCT04039243 Phase Not Applicable Recruiting 1 35 Months 90 Dina Hirshfeld-Becker, PhD, Jordan Holmen, BA 2020-12-10
A case-report study of a newborn infant with congenital factor X deficiency and COVID-19 infection Coronavirus disease 19 infection frozen plasma alone, tranexamic acid alone Female Shahid Beheshti University of Medical Sciences Phase Not Applicable Status not specified 0 1 2020-12-10
COVID-HIGH: HFNT Versus COT in COVID-19 Coronavirus disease 19 infection, Hypoxia, Respiratory failure, Respiratory tract infection, Viral pneumonia High Flow Nasal Therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone Palermo Azienda Ospedaliero - Universitaria Policlinico - Vittorio Emanuele Italy 2021-01-10 2022-03-01 1TH DEC 2020, COVID-HIGH, NCT04655638 Phase Not Applicable Not yet recruiting 0 13 Months 364 Alberto Noto, Alessio Mattei, Andrea Cortegiani, Andrea Cortegiani, MD, Annalisa Carlucci, Antonino Giarratano, Cesare Gregoretti, Claudia Crimi, Claudia Crimi, MD, Enrico Clini, Nicola Scichilone, Raffaele Scala 2020-12-09
Effectiveness of ICU diaries on satisfaction of family members of COVID-19 patients in the ICU Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Sapporo Medical University School of Medicine Japan 2020-09-01 UMIN000042681 Phase Not Applicable No longer recruiting 0 4 JUNPEI HARUNA 2020-12-08
MAPPING-V: Malaysian Public Preferences and Willingness to pay for Covid-19 Vaccination: A Discrete Choice Experiment Coronavirus disease 19 infection Covid-19 Vaccine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institutes of Health Malaysia Malaysia 2021-01-01 2021-12-31 57377, MAPPING-V, NMRR-20-2633-57377 Phase Not Applicable Not yet recruiting 0 12 Months MISS TEH HOON SHIEN 2020-12-11
nCoV-19 in elderly Coronavirus disease 19 infection Healthy volunteers accepted Hospital Kuala Lumpur Malaysia 2020-04-24 2020-05-24 54825, NMRR-20-2620-54825 Phase Not Applicable Status not specified 0 1 Month Dr Lee Yoong Wah 2020-12-11
RLX0120: Trial to study efficacy and safety of two doses of raloxifene in adult paucisymptomatic COVID-19 patients Coronavirus disease 19 infection raloxifene alone Estrogen receptor modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dompe Farmaceutici SpA Italy 2020-10-31 2020-003936-25, RLX0120, RLX0120 Phase 2/Phase 3 Clinical Recruiting 1 150 Flavio Mantelli 2020-12-09
Physical Activity During Covid-19 Lockdown Coronavirus disease 19 infection Physical Activity alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Tengku Ampuan Afzan, University Malaya Medical Centre Malaysia 2020-12-02 2021-03-17 55434, NMRR-20-2607-55434 Phase Not Applicable Status not specified 2 3 Months Dr Lim Zhuang Li, Dr. Choong Wai Kwong 2020-12-08
Phase II/III Study of COVID-19 DNA Vaccine (AG-0302-COVID19) Coronavirus disease 19 infection AG-0301-COVID19 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) AnGes MG Inc Japan Agency for Medical Research and Development Japan 2020-11-23 2022-03-31 AG0302-COVID19-JN-02, NCT04655625 Phase 2/Phase 3 Clinical Recruiting 0 16 Months 500 AnGes, Inc. Clinical Development 2020-12-16
COVID-VAC: Factors Influencing the Potential Acceptance of a Covid-19 Vaccine Among Healthcare Workers in a District Hosipital in Manjung, Perak Coronavirus disease 19 infection COVID-19 vaccine alone Healthy volunteers accepted HOSPITAL SERI MANJUNG Malaysia 2020-12-07 2021-01-31 57315, COVID-VAC, NMRR-20-2589-57315 Phase Not Applicable Not yet recruiting 0 1 Month 384 Chiew Shoen Chuen, Dr Lee Li Yuan 2020-12-11
COVID-19 Outbreak Management Coronavirus disease 19 infection JABATAN KESIHATAN NEGERI TERENGGANU Malaysia 2020-12-15 2021-02-28 56487, NMRR-20-2584-56487 Phase Not Applicable Status not specified 0 2 Months AHMAD FUAD BIN OMAR, Dr Goh Soo Ning 2020-12-11
COVIDEYE: Prevalence of SARS-CoV-2 Genome in Tears of Asymptomatic and Moderately Symptomatic COVID-19 Patients Coronavirus disease 19 infection PCR alone, conjunctival swab test alone, nasopharyngeal swab test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-12-31 2021-12-31 2020-A02996-33, APHP201268, COVIDEYE, NCT04654325 Phase Not Applicable Not yet recruiting 1 12 Months 1280 Antoine ROUSSEAU, PhD, Antoine Rousseau, PhD, Christelle Vauloup-Fellous, PhD 2020-12-09
Efficacy of prebiotic products on admitted patients with Covid-19 Coronavirus disease 19 infection probiotic intake alone, hydroxychloroquine plus remdesivir COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Shaheed Beheshti Medical University Iran 2020-09-22 IR.SBMU.RETECH.REC.1399.562, IRCT20161206031255N4 Phase 3 Clinical Recruiting 1 60 Afshin Zerghi, Roshanak Mokaberinejad 2020-12-09
Bromhexine hydrochloride for prophylaxis against COVID-19 Coronavirus disease 19 infection bromhexine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shaheed Beheshti Medical University Iran 2020-08-22 IR.SBMU.PHARMACY.REC.1399.247, IRCT20120703010178N22 Phase 3 Clinical No longer recruiting 0 1050 Hassan Yazdan Panah, Mohammad Sistanizad, Omid Moradi, Shadi Ziaie 2020-12-24
A clinical study of new scanning technique, dubbed the Xenon technique, to identify lung damage caused by COVID-19 Coronavirus disease 19 infection, Lung injury Xenon technique scan alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Oxford US Phase Not Applicable Recruiting 1 10 Professor Fergus Gleeson 2020-12-12
Clinical Outcome of Patients With COVID-19 Pneumonia Treated With Corticosteroids and Colchicine Coronavirus disease 19 infection, Viral pneumonia dexamethasone alone, colchicine plus dexamethasone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Clínica Medellín - Comprometidos con tu Salud Colombia 2020-03-20 2020-08-20 04-2020, NCT04654416 Phase Not Applicable Completed 1 5 Months 301 Miguel Alejandro Pinzón 2020-12-09
COMMUNITY: An adaptive, randomized, double-blind, placebo-controlled platform study designed to assess multiple candidates as a potential treatment for hospitalized patients with COVID-19 Coronavirus disease 19 infection multiple therapeutic candidates  alone, standard of care alone Amgen Inc, Takeda Pharmaceutical Co Ltd, UCB SA 2020-11-30 COMMUNITY Phase Not Applicable Recruiting 0 2020-12-12
A multi-center, double-blind, placebo-controlled, adaptive design, phase III clinical trial to evaluate the efficacy and safety of fostamatinib in adult, hospitalized COVID-19 patients Coronavirus disease 19 infection fostamatinib disodium alone Syk tyrosine kinase inhibitor Rigel Pharmaceuticals Inc 2020-12-31 Phase 3 Clinical Planned 0 2020-12-08
Prevalence of burnout, its associated factors among Dr and nurse of JB DHO during COVID-19 pandemic Coronavirus disease 19 infection Healthy volunteers accepted Universiti Sains Malaysia Malaysia 2021-01-01 2021-05-31 57271, NMRR-20-2579-57271 Phase Not Applicable Not yet recruiting 1 5 Months Dr NUR SUJAIHAH BINTI HANAFI 2020-12-09
A large-scale surveillance study of OneDraw Blood Collection Device to assess the prevalence of previous infection with COVID-19 Coronavirus disease 19 infection OneDraw device alone Drawbridge Health Inc, University of Cambridge UK Phase Not Applicable Recruiting 1 4000 Professor Nick Wareham 2020-12-08
Awareness, Knowledge and Attitudes of Obstetricians towards the use of Telemedicine in Antenatal Care: A Cross-sectional study in a Tertiary Government Hospital in the Philippines during the COVID-19 Pandemic Coronavirus disease 19 infection Telemedicine alone Philippine General Hospital Philippines 2020-10-20 2020-11-30 PHRR201201-003180 Phase Not Applicable Completed 1 1 Month Dominique Joyce M. Concepcion, Izabelle Julienne Figueras-Prieto, Regina Rosario M. Panlilio 2020-12-08
COVID-19 Cure Using Integrative Treatment Coronavirus disease 19 infection PAK-20 consumption alone, ajwa dates seed powder intake alone, integrative treatment intervention alone, kalonji intake alone, meat/ lentil intake alone, oniater intake alone, talbina intake alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Knowledge Research and Innovation Center, Pakistan, Iran 2020-01-17 2020-07-01 ChiCTR2000040632, IRCT20200823048495N1, KRIC/REC/1/01 Phase 1 Clinical Completed 2 5 Months 34 Muhammad Anwar Masood Behr, Muhammad Yahya Qureshi, Umber Nawaz 2020-12-14
Treatment With Pirfenidone for COVID-19 Related Severe ARDS Coronavirus disease 19 infection, Respiratory distress syndrome pirfenidone alone, standard of care alone PDGF receptor antagonist, TGF beta receptor antagonist, p38 MAP kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Soroka University Medical Center Roche Holding AG Israel 2020-11-08 2021-12-31 NCT04653831, SCRC20007 Phase 2 Clinical Recruiting 1 13 Months 100 Ori Galante, MD, Yasmeen Abu Fraiha, Yasmeen Abu Fraiha, MD 2020-12-09
Efficacy of barley water (Hordeum vulgare) in clinical outcome of COVID-19 patients Coronavirus disease 19 infection, Viral pneumonia barley water intake alone, current medication alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shiraz University of Medical Sciences Iran 2020-11-15 IR.SUMS.REC.1399.216, IRCT20150830023823N3 Phase 3 Clinical No longer recruiting 1 50 Abbas Rezaianzadeh, Ali Tavakoli 2020-12-18
To compare the effect of lying in face down position along with oxygen therapy given through high-flow nasal cannula device versus lying face down with oxygen given by non-rebreathing face mask in COVID-19 patients Coronavirus disease 19 infection, Hypoxia, Respiratory failure awake prone positioning alone, high-flow nasal cannula alone, oxygen alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences Patna India 2020-12-15 CTRI/2020/12/029587 Phase 2 Clinical Not yet recruiting 1 60 Rajnish Kumar 2020-12-09
Effects of PPE among Healthcare Workers Coronavirus disease 19 infection, Psychiatric disorder personal protective equipment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sri Ramachandra Medical College, Hospital & Research institute Sri Ramachandra University India 2020-12-15 CTRI/2020/12/029584 Phase Not Applicable Not yet recruiting 1 150 Dr Swathy Moorthy, DrSPThiagarajan 2020-12-07
CADE: Cardiac Assessment After Covid-19 Disease in Elite Altheltic Population Coronavirus disease 19 infection, Heart injury MRI alone, echocardiography alone, electrocardiogram alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) University Hospital, Montpellier Centre Hospitalier Universitaire de Nimes, Centre Hospitalier de Perpignan, Clinique du Millénaire, Rennes University Hospital, ligue nationale de Basket France 2020-04-01 2021-01-01 CADE, NCT04653857, RECHMPL20_0648 Phase Not Applicable No longer recruiting 1 9 Months 250 Christophe HEDON, MD, Stéphane CADE, MD 2020-12-09
Effectiveness of Unani add-on therapy in preventing the disease severity of COVID-19 infection Coronavirus disease 19 infection Variable regimens including Behidana, Unnab and Sapistan-unani decoction , Joshanda tea , Tiryaq-e-Arba , azithromycin , hydroxychloroquine , vitamin C , zinc Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Central Council for Research in Unani Medicine Ministry of Ayush India 2020-12-04 CTRI/2020/12/029575 Phase 3 Clinical Not yet recruiting 1 100 Dr Jugal Kishore, Dr Rohit Kumar, Dr Tamanna Nazli, Prof Jugal Kishore 2020-12-09
Study of the safety of hyperimmune bovine milk and colostrum against COVID-19 Coronavirus disease 19 infection bovine Colostrum plus bovine milk Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Isfahan University Isfahan Oil Refinery Iran 2020-11-10 2020-11-25 IR.MUI.MED.REC.1399.672, IRCT20200927048849N1 Phase 1 Clinical Completed 1 40 Hassan Niliahmadabadi, Rasoul Roknizadeh, Somayeh Sadeghi 2020-12-08
A study of cyclophosphamide outcomes in patients with COVID-19 Coronavirus disease 19 infection, End stage renal disease, Respiratory distress syndrome, Vasculitis cyclophosphamide plus prednisone Metropolitan Hospital Center Phase Not Applicable Status not specified 0 3 2020-12-07
GraphealNpas: Feasibility and Analytical Performance of TestNPass (IVDMD) for COVID-19 Diagnosis on Saliva Sample Coronavirus disease 19 infection TestNPass diagnotic medical device (Grapheal SAS) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Grenoble Grapheal SAS France 2020-12-15 2021-03-15 2020-A03087-32, 38RC20.378, GraphealNpas, NCT04654442 Phase Not Applicable Not yet recruiting 1 3 Months 60 Benjamin Némoz, MD, Benjamin Némoz, Némoz, Marion Le Maréchal, MD, Pierre AUDOIN, MS 2020-12-09
NIVHOC: A clinical trial to compare the effect of non-invasive ventilation with high-flow nasal oxygen therapy versus only high flow nasal oxygen therapy in COVID 19 patients with respiratory failure Coronavirus disease 19 infection, Respiratory failure face mask alone, non-invasive ventilation based high flow nasal oxygen therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences Patna India 2020-12-12 CTRI/2020/12/029585, NIVHOC Phase Not Applicable Not yet recruiting 1 100 Kunal Singh 2020-12-09
ROCD: A study of kidney Problems with covid 19 in admitted patients at a teritiary care hospital Coronavirus disease 19 infection, Renal disease Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Yenepoya Medical college India 2020-12-21 CTRI/2020/12/029581, ROCD Phase Not Applicable Not yet recruiting 1 300 Dr Santhosh Pai, Dr Santhosh pai 2020-12-09
Various Blood Parameters Affecting outcome in ICU Patients Coronavirus disease 19 infection, Vitamin D deficiency Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) JSS University India 2020-12-15 CTRI/2020/12/029586 Phase Not Applicable Not yet recruiting 1 150 DR AKSHAY, DR Rajalakshmi R 2020-12-09
Aerosol Particle Concentrations Among Different Oxygen Devices for Spontaneous Breathing Patients With Tracheostomy Coronavirus disease 19 infection, Respiratory disease Airvo2 (Fisher and Paykel Healthcare Ltd) alone, high-flow high humidity oxygen therapy alone, tracheostomy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rush University Medical Center US 2021-01-31 2021-05-31 HFOT-TRACH-AEROSOL, NCT04654754 Phase Not Applicable Not yet recruiting 1 4 Months 12 Jie Li, Jie Li, PhD 2020-12-22
Study of AffloVest in At-Risk Respiratory Patients During COVID-19 Pandemic Chronic obstructive pulmonary disease, Coronavirus disease 19 infection, Cough Afflovest device alone, Standard Care alone, digital thermometer alone, high frequency chest wall oscillation (HFCWO) therapy alone, pulse oximeter alone, spirometer alone, telehealth training alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mount Sinai Medical Center International Biophysics Corporation, SPARK Healthcare Consultants, LLC US 2020-12-31 2021-11-30 GCO 20-2667, ISMMS-AFF-20, NCT04654481 Phase Not Applicable Recruiting 1 11 Months 30 Elinor L Schwind, MS, Patricia Walker, MD, Teresa Demarco, PTA 2020-12-09
Serial sero-epidemiological surveillance study to monitor the trend of SARS-CoV-2, Dengue and Chikungunya infection transmission in the Vellore Demographic Health Surveillance System (HDSS) Chikungunya virus infection, Coronavirus disease 19 infection, Dengue virus infection neutralization assay alone Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Christian Medical College, Vellore, India Biotechnology Industry Research Assistance Council, National BioPharma Mission India 2020-12-10 CTRI/2020/12/029564 Phase Not Applicable Not yet recruiting 1 5000 Winsley Rose 2020-12-08
ReCOV: RT-PCR Database Analysis for COVID-19 Infections and Re-infection Coronavirus disease 19 infection RT-PCR alone University Hospital, Montpellier Centre Hospitalier Universitaire de Nimes, Centre National de la Recherche Scientifique (CNRS), Laboratoire Pasteur-Cerba, MIVEGEC, MPL Analysis Laboratoires France 2020-02-01 2021-03-30 NCT04653844, RECHMPL20_0640, ReCOV Phase Not Applicable No longer recruiting 1 13 Months 7000000 Vincent Foulongne, PhD 2020-12-09
A case report study of severe encephalopathy or focal brain lesions in children with multisystem inflammatory syndrome associated with COVID-19 Brain disease, Coronavirus disease 19 infection, Inflammatory disease Variable regimens including IV immunoglobulin , anakinra , methylprednisolone Type I IL-1 receptor antagonist Male, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Columbia University Irving Medical Center Phase Not Applicable Status not specified 0 1 2020-12-07
AtemNHK: Effects of Integrative Medicine on Infectious Respiratory Diseases Including COVID-19 Coronavirus disease 19 infection, Respiratory tract infection protective lifestyle intervention alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Charite University Germany 2020-12-31 2021-12-31 ATEMNHK, AtemNHK, NCT04653727 Phase Not Applicable Not yet recruiting 1 12 Months 3000 Andreas Michalsen 2020-12-09
Evaluation of prophylaxis induced by ivermectin in populations exposed to COVID-19 patients Coronavirus disease 19 infection ivermectin alone Chloride channel modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Akam Tejarat Fartak Farasoo Iran 2020-11-30 IR.QUMS.REC.1399.261, IRCT20200408046987N3 Phase 3 Clinical Recruiting 3 800 Abbas Allami, Alireza Mehralian, Morteza Shakhsi Niaee, Nematollah Gheibi, fatemeh samieerad 2020-12-08
Effect of GRAPEX in treatment of COVID-19 Coronavirus disease 19 infection Grapex alone, Standard country protocol drug therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Abadan University of Medical Sciences Iran 2021-01-08 IR.ABADANUMS.REC.1399.098, IRCT20200921048783N1 Phase 3 Clinical Not yet recruiting 1 80 Hoda Mojiri-Forushani, Hoda Mojjiri-Forushani, Sara Mobarak 2020-12-08
A phase II study to evaluate PIC1-01 for the treatment of patients with hypoxic ischemic encephalopathy (HIE) Brain hypoxia-ischemia, Coronavirus disease 19 infection PIC1-01 alone Complement C1s subcomponent inhibitor ReAlta Life Sciences Inc Europe Phase 2 Clinical Planned 0 2020-12-07
The effect of Helichrysum pseudoplicatum syrup on clinical manifestations of patients with COVID-19 Coronavirus disease 19 infection, Respiratory tract infection Helichrysum pseudoplicatum syrup (Shahid Beheshti, Arak University of Medical Sciences) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Arak University of Medical Sciences and Health Services Iran 2020-05-18 IR.ARAKMU.REC.1399.003, IRCT20180610040049N6 Phase 3 Clinical No longer recruiting 1 60 Alireza Kamali, Hosein Sarmadian, Mohammad KamaliNejad, Seied Amirhosein Latifi 2020-12-08
A pivotal, phase II/III clinical trial to evaluate SCB-2019 in combination with Dynavax’s advanced CpG 1018 adjuvant plus alum for the prevention of SARS-CoV-2 infection Coronavirus disease 19 infection Variable regimens including CpG 1018 adjuvant , SCB-2019 , alum COVID19 Spike glycoprotein modulator Clover Biopharmaceuticals AUS Pty Ltd 2021-06-30 Phase 2/Phase 3 Clinical Planned 0 2020-12-07
Serological investigations of blood donors from the city and area around Magdeburg for antibodies against SARS-CoV-2 (COVID-19) Coronavirus disease 19 infection serological examination alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Institut fUr Medizinische Mikrobiologie und Krankenhaushygiene Institut fur Sozialmedizin und Gesundheitssystemforschung, Ministerium für Wirtschaft, Wissenschaft und Digitalisierung des Landes Sachsen-Anhalt Germany 2021-01-15 163/20, DRKS00023263 Phase 4 Clinical Not yet recruiting 1 4500 Heuft Hans-Gert, Stephan Kramer 2020-12-08
A retrospective, case series study to describe clinical outcomes associated with tocilizumab compared with those not receiving tocilizumab in critically ill patients with severe COVID-19 Coronavirus disease 19 infection tocilizumab alone Atrium Health Phase Not Applicable Status not specified 0 49 2020-12-07
A follow-up study of long-term prognosis in patients with novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Xi'an Children's Hospital China 2020-02-02 2021-05-31 ChiCTR2000040628 Phase Not Applicable Recruiting 1 15 Months 430 Guo Yaling, Xu You, Yang Mingb, Yang Puye 2020-12-07
Novel coronavirus pneumonia (COVID-19) treated with different antiviral regimens: a medical records based study for analysis of therapeutic effect and length of stay of hospitalization Coronavirus disease 19 infection hormone therapy alone, Variable regimens including Lianhua Qingwen , abidol , interferon , oseltamivir , ribavirin Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) People's Hospital of Shapingba District, Chongqing City China 2020-12-01 2022-11-30 2020SQKWLH016, ChiCTR2000040571 Phase Not Applicable Not yet recruiting 1 24 Months 180 Huang Zi Yang 2020-12-07
Impact of COVID-19 pandemic on post graduate medical trainees in India Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Post Graduate Institute of Dental Sciences (PGIMS) India 2020-12-06 BREC/20/204, CTRI/2020/12/029515 Phase Not Applicable Not yet recruiting 1 1000 Jyoti Khanna 2020-12-07
An exploratory, phase II, physician-initiated clinical trial investigating the efficacy and safety of TM-5614 in patients with novel coronavirus pneumonia Coronavirus disease 19 infection, Viral pneumonia TM-5614 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Japan Agency for Medical Research and Development Japan 2020-07-20 2021-01-31 jRCT2021200018 Phase 2 Clinical Recruiting 1 6 Months 30 Fumio Sakamaki, Harigae Hideo, Hideo Zhang, Hisatoshi Sugiura, Isao Ito, Keisuke Tomii, Koichiro Asano, Sakurako Tajiri, Yasunari Miyazaki 2020-12-07
MeDiCo- health Study: Eating habits during the Covid-19 pandemic Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Technical University of Munich EIT Food iVZW, Personalized nutrition and vitamins - LOEWI Germany 2020-12-03 655/20 S, DRKS00022514, MeDiCo- health Study Phase Not Applicable Not yet recruiting 1 200 Laura Mengel, Thomas Skurk 2020-12-07
CHDR2044: Healthy volunteers blood sampling Coronavirus disease 19 infection flow cytometry alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Leyden Laboratories BV Netherlands 2020-11-03 2021-01-31 CHDR2044, NL75505.058.20, NL9045 Phase Not Applicable Not yet recruiting 1 2 Months 20 I.M.C. de Visser-Kamerling 2020-12-08
DF in COVID19: A Single-Arm Safety and Feasibility Study of Defibrotide for the Treatment of Severe COVID-19 Coronavirus disease 19 infection, Viral pneumonia defibrotide (iv, veno-occlusive disease), Gentium alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Brigham & Women's Hospital Jazz Pharmaceuticals plc US 2021-01-01 2023-11-01 2020P003203, DF in COVID19, NCT04652115 Phase 2 Clinical Not yet recruiting 1 34 Months 42 Paul G Richardson, MD, Paul G. Richardson 2020-12-08
Exploratory research on severity indicators for COVID-19 patients Coronavirus disease 19 infection, Viral pneumonia Body motion sensor alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Japan Agency for Medical Research and Development Japan 2020-07-30 2020-12-31 jRCT1052200041 Phase Not Applicable Not yet recruiting 1 5 Months 40 Eiji Asanoi, Naho Fujiwara, Shigeru Miyagawa, Sho Saito, Yoshiki Sawa, Yukio Abe, sawa Yoshiki 2020-12-07
Effect of the COVID-19 Public Health Crisis on the Mental Health and Physical Well-Being of Cancer Patients, the Coping With COVID Study Acute stress disorder, Coronavirus disease 19 infection, Psychiatric disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) MD Anderson Cancer Center National Cancer Institute US 2020-07-13 2021-03-31 2020-0451, NCI-2020-06556, NCT04652505 Phase Not Applicable Recruiting 1 8 Months 700 Tamara E Lacourt, Tamara E. Lacourt 2020-12-08
CoronaVac3CL: Efficacy, Safety, and Immunogenicity of an Inactivated Vaccine Against COVID-19 in High Infection Risk Adults Coronavirus disease 19 infection CoronaVac alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Pontificia Universidad Catolica De Chile Ministry of Health, Sinovac Research & Development Co Ltd Chile 2020-11-27 2022-03-31 200708006, CoronaVac3CL, NCT04651790 Phase 3 Clinical Recruiting 1 16 Months 2300 Alvaro Rojas, MD, Carolina Iturriaga, Nurse, Katia Abarca, MD, María Soledad Navarrete, Nurse 2020-12-09
An observational, single-center study to evaluate the prevalence of major bleeding events in patients with COVID-19 receiving intensive thromboprophylaxis Bleeding, Coronavirus disease 19 infection enoxaparin alone, heparin alone Università della Svizzera italiana Switzerland Phase Not Applicable Status not specified 1 270 2020-12-04
WAYRA: Home-based Respiratory Physiotherapy and Telephone-Based Psychological Support in Severe COVID-19 Patients Coronavirus disease 19 infection home-based respiratory physiotherapy alone, telephone-based psychological support alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Universidad Peruana Cayetano Heredia Johns Hopkins University, London School of Hygiene and Tropical Medicine Peru 2020-10-26 2021-03-30 202852, NCT04649736, WAYRA Phase Not Applicable Recruiting 1 5 Months 108 Anderson N. Soriano-Moreno, MD, Andres G Lescano, PhD, MHS, Germán Málaga, MD, MSc, Stella M Hartinger, MSc, PhD, William Checkley, MD, PhD 2020-12-07
CovExc: Muscular Rehabilitation by Eccentric Exercise After Severe COVID-19 Infection Coronavirus disease 19 infection rehabilitation by eccentric exercises alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Clermont-Ferrand GIRCI Auvergne Rhône-Alpes, Ministry of Health, France France 2020-06-05 2021-12-05 2020-A01201-38, CovExc, NCT04649086, PHRCI 2020 COSTE (COVEXC) Phase Not Applicable Recruiting 5 18 Months 120 Dominic PERENNOU, MD, PhD, Emmanuel COUDEYRE, MD, PhD, Emmanuelle CHALEAT-VALAYER, MD, PhD, Lise Laclautre, PharmD, Léonard FEASSON, MD, PhD, Nicolas COSTE, MD, MSc, Paul ORNETTI, MD, PhD 2020-12-07
Packaging and Disseminating the JOIN for ME Program in Low-Income Settings Coronavirus disease 19 infection, Obesity JOIN for ME program alone Healthy volunteers accepted, Children (6-12 yrs) Miriam Hospital Brandeis University, Brown University, Tufts University, University of North Carolina US 2021-01-31 2023-02-28 5U18DP006429-02, NCT04647760 Phase Not Applicable Not yet recruiting 1 25 Months 128 Andrea M Grenga, BA, Elissa Jelalian, PhD 2020-12-07
SHYCOV: Silent Hypoxia and Awake Proning in COVID-19 Patients Coronavirus disease 19 infection, Hypoxia physiotherapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ostfold Hospital Trust Norway 2020-11-30 2021-12-31 NCT04647747, SHYCOV, SHYCOV2020 Phase Not Applicable Not yet recruiting 1 13 Months 40 Hans Joakim Myklebust-Hansen 2020-12-07
Rapid Development and Implementation of a Remote ECG-monitored, Prospective, Randomized Clinical Trial During a Pandemic: Hydroxychloroquine Prophylaxis in COVID-19 Household Contacts Coronavirus disease 19 infection hydroxychloroquine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bryn Mawr Hospital Sharpe-Strumia Foundation US 2020-05-27 2020-11-15 BM02332, NCT04652648 Phase 4 Clinical Completed 3 5 Months 54 Luciano kapelusznik 2020-12-07
PCR Cycle Threshold Values and COVID-19 Outcomes Coronavirus disease 19 infection real-time polymerase chain reaction alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospitals of North Midlands NHS Trust UK 2020-11-24 2021-03-31 286389, NCT04651413 Phase Not Applicable Recruiting 1 4 Months 800 Keira Watts, Robert Bowler, Robert J Bowler, Timothy Kemp 2020-12-08
The Protective Potential of Exercise Training on the Cardiopulmonary Morbidity After COVID-19 Coronavirus disease 19 infection high intensity interval training alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rigshospitalet Denmark 2021-01-01 2021-12-31 H-20033733 V.2, NCT04647734 Phase Not Applicable Not yet recruiting 1 12 Months 40 Regitse Christensen, MD, PhD, Ronan Berg, DMSc, MD 2020-12-08
COMBO: Camostat With Bicalutamide for COVID-19 Coronavirus disease 19 infection Standard of care alone, camostat mesylate alone, bicalutamide plus camostat mesylate Androgen receptor antagonist, Serine protease inhibitor, Transmembrane serine protease 2 inhibitor, Trypsin inhibitor Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sidney Kimmel Comprehensive Cancer Center US 2021-01-31 2023-01-31 COMBO, COV2005, IRB00254142, NCT04652765 Phase 1 Clinical Not yet recruiting 1 24 Months 60 Aliya Lalji, MD, Catherine H Marshall, MD/MPH 2020-12-08
LYT-100 in Post-acute COVID-19 Respiratory Disease Coronavirus disease 19 infection, Fibrosis, Inflammatory disease, Viral pneumonia deupirfenidone alone PDGF receptor antagonist, TGF beta receptor antagonist, p38 MAP kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) PureTech Health Plc Clinipace Worldwide, Novotech (Australia) Pty Ltd Romania, US 2020-12-11 2021-12-31 LYT-100-2020-02, NCT04652518 Phase 2 Clinical Recruiting 3 12 Months 168 Adrian Streinu-Cercel, MD, PhD, Barry Sigal, MD, FCCP, Heather Paden, Jack Bissett, MD, Site Coordinator, Toby Maher, MD 2020-12-17
Testing the effectiveness of almitrine bismesylate in the treatment of COVID-19 Coronavirus disease 19 infection, Hypoxia, Viral pneumonia almitrine bismesylate alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Oxford LifeArc UK 2020-04-30 2021-09-30 2020-002567-57, CPMS 47241, IRAS 282381, ISRCTN11713182 Phase 2 Clinical Recruiting 3 17 Months 116 Dr Talbot 2020-12-08
FSC19-KN: Single-Center, Prospective, Controlled, Follow-up Study of COVID-19 Patients District Konstanz Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hegau-Bodensee-Klinikum Deutsche Forschungsgemeinschaft (DFG), German Federal Ministry of Education and Research Germany 2021-01-01 20-1020, DRKS00022409, FSC19-KN Phase Not Applicable Not yet recruiting 1 400 Marc Kollum 2020-12-08
Observational, Retrospective Study to Evaluate Coagulation Changes and the Influence of Antithrombin III Treatment in Patients With Severe COVID-19 Infection Blood clotting disorder, Coronavirus disease 19 infection antithrombin III alone Octapharma AG France, Germany, Austria 2020-10-19 2021-01-31 ATN01, NCT04651400 Phase Not Applicable Recruiting 5 3 Months 300 Mikaela Raymond 2020-12-08
A retrospective study to evaluate the effects of tocilizumab in the treatment of critical COVID-19 pneumonia Coronavirus disease 19 infection, Pneumonia Mechanical ventilation alone, tocilizumab alone, Variable regimens including Standard hospital protocol Stony Brook University Hospital US Phase Not Applicable Status not specified 1 115 2020-12-04
HOO-COVID: Efficacy and Safety of Ozonized Oil (HOO) in COVID-19 Patients Coronavirus disease 19 infection ozonized oil alone, routine standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Istituto Neurologico Mediterraneo NEUROMED Italy 2021-01-31 2021-08-31 DEP_052020, HOO-COVID, NCT04651387 Phase Not Applicable Not yet recruiting 1 7 Months 74 Licia Iacoviello, MD, PhD 2020-12-07
CAGE: COVID-19 And geko Evaluation Coronavirus disease 19 infection geko T3 device alone, peroneal nerve neuromuscular electrical stimulation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Lawson Health Research Institute Canada 2020-12-31 2021-04-30 CAGE, ISS-COV-002, NCT04651374 Phase Not Applicable Not yet recruiting 1 4 Months 40 Jessica Sturt-Smith, Tina Mele, Tina Mele, MD PhD FRCSC 2020-12-07
A retrospective, observational study to evaluate the treatment responses of criteria-based tocilizumab therapy for COVID-19 respiratory infection in ICU and non-ICU patients Coronavirus disease 19 infection, Respiratory tract infection tocilizumab alone Jefferson Health (US) Phase Not Applicable Status not specified 0 170 2020-12-04
A study to evaluate the efficacy of DeepCOVID-XR, the machine-learning algorithm, to detect COVID-19 by analyzing X-ray images of the lungs Coronavirus disease 19 infection DeepCOVID-XR alone Northwestern University US Phase Not Applicable Status not specified 1 2020-12-04
Safety and Immunogenicity of SARS-CoV-2 mRNA Vaccine (BNT-162b2) in Chinese Healthy Population Coronavirus disease 19 infection, Viral pneumonia BNT-162b2 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry BioNTech SE, Jiangsu Province Centers for Disease Control and Prevention Shanghai Fosun Pharmaceutical Industry Development Co Ltd China 2020-11-25 2021-12-31 BNT162-06, ChiCTR2000040044, NCT04649021 Phase 2 Clinical Recruiting 5 13 Months 960 BioNTech Responsible Person, BioNTech clinical trial information desk, Wang Wei, Zhu Fengcai 2020-12-15
Serological Profile of Children and Young Adolescents With at Least One COVID-19 Diagnosed Family Member Coronavirus disease 19 infection Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universita degli Studi di Milano Italy 2020-12-05 2021-12-31 GMT_CD_CT_LG_EB_10_2020, NCT04649944 Phase Not Applicable Not yet recruiting 1 12 Months 40 Giampietro Farronato, DDS, Gianluca Martino Tartaglia, DDS PhD, Gianluca Tartaglia, Professor, Marco Farronato, 2020-12-08
The effect of Steroid on the outpatient treatment of COVID-19 Coronavirus disease 19 infection prednisolone alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Isfahan University of medical Sciences Iran 2020-12-21 IR.MUI.MED.REC.1399.781, IRCT20171219037964N2 Phase 3 Clinical Recruiting 3 70 Babak Amra, Dr. Babak Amra, Dr. Forough Soltaninejad, Dr. Mehrdad Salahi, Shaghayegh Haghjoo 2020-12-22
SAVID: Serum Amyloid A as a prognostic marker for disease severity and mortality in COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Franciscus Gasthuis & Vlietland Siemens Healthcare GmbH Netherlands 2021-01-01 2021-12-31 NL9082, SAVID Phase Not Applicable Planned 1 12 Months 400 Nadine Pouw 2020-12-07
High-Flow Nasal Cannula for severe COVID-19, a multicenter, prospective, cohort study Coronavirus disease 19 infection High-Flow Nasal Cannula alone Franciscus Gasthuis & Vlietland 2020-12-01 2021-12-31 NL9067 Phase Not Applicable Planned 0 13 Months 200 Yasemin Türk 2020-12-04
SHARP-COVID: COVID-19 pandemic impact on severe asthma patients care in Europe Asthma, Coronavirus disease 19 infection Amsterdam University Medical Center Netherlands 2020-11-22 2021-01-31 NL9063, SHARP-COVID Phase Not Applicable Not yet recruiting 1 2 Months 900 Katrien Eger 2020-12-04
Estimation of Dynamics of Humoral and Cellular Immunity in COVID-19 Patients Coronavirus disease 19 infection, Viral pneumonia Humoral and cellular immunity test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus Belarusian State Medical University, Belarussian Research Institute for Epidemiology and Microbiology Belarus 2020-10-01 2021-12-31 IBCE-COVID19-IMMUNITY, NCT04649840 Phase Not Applicable Recruiting 1 15 Months 60 Andrei Hancharou, MD, PHD 2020-12-04
A retrospective study on clinical outcome of tocilizumab in relation to respiratory status improvements and to analyze the association between initial inflammatory markers and treatment outcomes in patients with COVID-19 Coronavirus disease 19 infection tocilizumab alone Saint Barnabas Health Care Systems Phase Not Applicable Status not specified 0 84 2020-12-09
The Impact of COVID-19 on Surgical Practice in Jordan During the Second Outbreak Coronavirus disease 19 infection Yarmouk University Jordan 2020-11-01 2020-11-10 NCT04650035, THE IMPACT OF COVID-19 JORDAN Phase Not Applicable Completed 1 60 Raed M Ennab 2020-12-04
VR Baby, a virtual reality learning environment - does it help medical students to learn about complex topics in obstetrics and gynecology? Coronavirus disease 19 infection Brightspace eLearning University platform alone, VR Baby virtual reality learning environment intervention alone Healthy volunteers accepted University College Dublin Ireland 2020-01-27 2021-03-31 ISRCTN19845486 Phase Not Applicable No longer recruiting 1 14 Months 40 Prof Fionnuala McAuliffe 2020-12-08
AirFLO2 Treatment for Hypoxia and/or Tachypnea in Patients With COVID-19 (AirFLO2) Coronavirus disease 19 infection, Hypoxia, Tachypnea AirFLO2 device alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Duke University Medex Inc US 2020-12-04 2021-06-30 NCT04649775, PRO00105246 Phase Not Applicable Not yet recruiting 1 6 Months 50 Catherine M Foss, BS, Loretta Que, MD, Maria A Santoro, MA 2020-12-04
Early@home Coronavirus disease 19 infection, Viral pneumonia oxygen therapy alone, telemonitoring alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universiteit Utrecht Netherlands 2021-01-11 2021-05-31 NL9081, TBA Phase Not Applicable Not yet recruiting 0 4 Months 100 Harriët van Goor 2020-12-11
Prolonged grief disorder due to the Covid-19 lockdown? - Impact of contact restrictions on the relatives of patients who died during lockdown Anxiety disorder, Coronavirus disease 19 infection, Depression, Psychiatric disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Gießen and Marburg Germany 2020-12-02 178/20, DRKS00023713 Phase Not Applicable Recruiting 0 567 Mr. Dr. med. Christian Volberg 2020-12-11
SOLIDARITY: WHO COVID-19 Solidarity Trial for COVID-19 Treatments Coronavirus disease 19 infection acalabrutinib alone, interferon beta-1a alone, remdesivir alone Btk tyrosine kinase inhibitor, COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The University of The West Indies-Mona Jamaica 2020-12-01 2021-12-31 NCT04647669, SOLIDARITY, SRD/ETH/20 Phase 3 Clinical Not yet recruiting 1 13 Months 100 Marvin E Reid, MB BS PhD, Marvin Reid, Naydenne Williams, MBBS DM, Tomlin Paul 2020-12-04
TeenCove: A Study to Evaluate the Safety, Reactogenicity and Effectiveness of mRNA-1273 Vaccine in Adolescents 12 to < 18 Years Old to Prevent COVID-19 Coronavirus disease 19 infection mRNA-1273 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs) ModeRNA Therapeutics Biomedical Advanced Research and Development Authority (BARDA) US 2020-11-30 2022-06-30 MRNA-1273-P203, NCT04649151, TeenCove Phase 2/Phase 3 Clinical Recruiting 7 19 Months 3000 Moderna Clinical Trials 2020-12-23
Profiling Recovery of Those Discharged Into the Community With COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Derby Sheffield Hallam University, University Hospitals Of Derby and Burton NHS Foundation Trust UK 2021-01-04 2021-12-17 COVID-19-UOD&RDH20/21, NCT04649957 Phase Not Applicable Not yet recruiting 1 11 Months 100 Amanda Baxendale, PhD, Mark A Faghy, PhD, Ruth Ashton, PhD, Tom Bewick, MD, Tom Maden-Wilkinson, PHD 2020-12-07
Well-being in Cancer Patients With Neuropathy During COVID-19 Who Participated in Prior Clinical Trials Coronavirus disease 19 infection, Neuropathic pain MD Anderson Cancer Center National Cancer Institute US 2020-05-26 2021-07-01 2020-0508, 2020-0508, NCI-2020-06014, NCT04650178 Phase Not Applicable Recruiting 1 13 Months 274 Sarah Prinsloo 2020-12-04
Differences in Exhaled Breath by Using Ion Mobility Spectrometry (IMS) in Subjects Tested for SARS-CoV-2 Infection (COVID-19 Disease) Coronavirus disease 19 infection Ion Mobility Spectrometry (IMS) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) B Braun Melsungen AG CeGaT Germany 2020-12-14 2021-05-31 HC-N-H-2006, NCT04649931 Phase Not Applicable Recruiting 1 5 Months 400 Juergen Schaefer, Prof. Dr., Study Manager 2020-12-19
Perception of the COVID-19 Pandemic in Patients With Hematological or Solid Neoplasias Acute stress disorder, Coronavirus disease 19 infection, Hematological neoplasm, Solid tumor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Medizinische Universität Innsbruck Austria 2020-11-23 2020-12-31 1264/2020, NCT04649320 Phase Not Applicable Recruiting 1 1 Month 300 Reinhard Stauder, M.D. 2020-12-04
COVID-19 Nasal Swab Trial Coronavirus disease 19 infection CanSwab alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Orthopaedic Innovation Center Inc Canada 2020-12-31 2021-02-28 B2020:121, NCT04649424 Phase Not Applicable Not yet recruiting 1 2 Months 72 Anand Kumar, MD, Gloria Vasquez-Grande, MD, Kerry Dust, MD, Paul Van Caeseele, MD, Sarah Tran, Trevor Gascoyne 2020-12-04
ResCOVID: A Clinical Trial for Hospitalized Patients With COVID-19 in Ceara Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Escola de Saúde Pública do Ceará Brazil 2020-04-02 2021-12-30 3.948.100, NCT04649827, ResCOVID Phase Not Applicable Recruiting 1 20 Months 3000 Jadson A' Franco, Marcelo A Holanda, PHD 2020-12-04
Convalescent Plasma for Treatment of COVID-19: An Open, Randomized, Controlled Trial Coronavirus disease 19 infection SARS-CoV-2 convalescent plasma alone, steroid therapy alone, SARS-CoV-2 convalescent plasma plus betamethasone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Karolinska University Hospital Danderyd Hospital, Falu Hospital, Karolinska Institutet Sweden 2020-12-03 2022-02-01 CP3, NCT04649879 Phase 2/Phase 3 Clinical Not yet recruiting 3 13 Months 920 Alexandre Bonnard, MD, Anne Börjesson Hanson, Hanna Sahlgren, MD, Joakim Dillner, Joakim Dillner, MD, PhD, Johan Rudling, MD, Johan Ursing, MD, PhD, Karin Norlin, Karl Hagman, MD, Lena Flod, Magnus Hedenstierna, MD, PhD, Maria Eriksdotter, Miia Kivipelto, Ulf Öhlund 2020-12-07
COVID-19 Thrombosis Prevention Trials: Post-hospital Thromboprophylaxis Coronavirus disease 19 infection, Deep vein thrombosis, Ischemic stroke, Lung embolism, Myocardial infarction, Thromboembolism apixaban alone Factor Xa antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Duke University National Heart Lung and Blood Institute US 2020-12-31 2021-09-30 NCT04650087, PRO00107078 Phase 3 Clinical Not yet recruiting 1 9 Months 5320 Thomas L. Ortel, MD, PhD, Thomas Ortel, M.D., Ph.D, Tracy Wang, MD 2020-12-04
Effect of Favipiravir on outpatient treatment of COVID-19 Coronavirus disease 19 infection favipiravir alone RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Isfahan University of medical Sciences Iran 2020-12-21 IR.MUI.MED.REC.1399.780, IRCT20171219037964N3 Phase 3 Clinical Recruiting 3 70 Babak Amra, Dr. Babak Amra, Dr. Forough Soltaninejad, Dr. Mehrdad Salahi, Shaghayegh haghjooy Javanmard 2020-12-23