Last updated: Jun 26, 2020 - 02:00 BST
| An exploratory, non-randomized, open-label, single-arm study to evaluate the safety of ADR-001 in patients with severe pulmonary inflammation caused by SARS-CoV-2 infection |
Coronavirus disease 19 infection, Lung inflammation, Viral pneumonia |
ADR-001 alone |
|
|
Rohto Pharmaceutical Co Ltd |
|
Japan |
2020-08-31 |
2021-12-31 |
|
Phase Not Applicable |
Planned |
0 |
16 Months |
6 |
|
2020-06-25 |
| A study to assess the effect of gelsolin, BioAegis Therapeutics in patients with COVID-19 pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
gelsolin, BioAegis Therapeutics alone |
Actin antagonist |
|
BioAegis Therapeutics Inc |
|
US |
|
|
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Phase Not Applicable |
Planned |
0 |
|
|
|
2020-06-25 |
| A clinical study of virus-neutralizing antibody therapeutic (COVID19), Kaneka in Coronavirus disease 19 infection |
Coronavirus disease 19 infection |
virus-neutralizing antibody therapeutic (COVID19), Kaneka alone |
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Kaneka Corp |
Tokyo University of Science |
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-06-25 |
| Effectiveness of Elman tablet on COVID-19 infection severity |
Coronavirus disease 19 infection |
Variable regimens including Elman (Simorgh Attar Neishabour Pharmaceutical) , hydroxychloroquine , lopinavir + ritonavir |
HIV protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Esfarayen Faculty of Medical Sciences |
|
Iran |
2020-07-09 |
|
IR.ESFARAYENUMS.REC.1399.003, IRCT20200609047707N1 |
Phase 3 Clinical |
Not yet recruiting |
0 |
|
90 |
Eshagh Ildarabadi, Essa Tohidi, Seyed Javad Hosseini |
2020-06-25 |
| CHLORAZ: An Observational Study to Assess the Protocol for the COVID-19 Treatment in Burkina Faso |
Coronavirus disease 19 infection |
Variable regimens including azithromycin , chloroquine phosphate , hydroxychloroquine |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Muraz |
|
Burkina Faso |
2020-05-01 |
2020-12-31 |
CHLORAZ, IRSS-URCN-CM 001, NCT04445441 |
Phase Not Applicable |
Recruiting |
2 |
8 Months |
150 |
Espérance Ouédraogo, MD, Msc, Halidou Tinto, PhD, Houreratou Barry, MD, Msc, Innocent Valea, PhD, Marc Tahita, PhD |
2020-06-25 |
| KAP of New Normal Among HCW in Hospital Kuala Lumpur and Hospital Sungai Buloh Regarding COVID-19 |
Coronavirus disease 19 infection |
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University of Malaya |
|
|
2020-07-01 |
2021-06-30 |
55330, NMRR-20-1212-55330 |
Phase Not Applicable |
Status not specified |
0 |
12 Months |
|
Dr Sri Viknarajan A/L Puvendran |
2020-06-25 |
| Modelling of COVID-19 in Malaysia |
Coronavirus disease 19 infection |
|
|
|
University of Malaya |
|
Malaysia |
2020-06-22 |
2020-12-31 |
55087, NMRR-20-1208-55087 |
Phase Not Applicable |
Status not specified |
1 |
6 Months |
|
Dr Vivek Jason a/l Jayaraj |
2020-06-25 |
| COVID-19 infected HCW |
Coronavirus disease 19 infection |
|
|
|
Hospital Queen Elizabeth |
|
Malaysia |
2020-08-01 |
2021-07-31 |
55463, NMRR-20-1207-55463 |
Phase Not Applicable |
Status not specified |
1 |
12 Months |
|
Dr Hor Chee Peng, Ms. Teong Win Zee |
2020-06-25 |
| Phase I Clinical Study of Recombinant Novel Coronavirus Vaccine (CHO Cells) |
Coronavirus disease 19 infection |
recombinant new coronavirus vaccine (CHO cell) alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Anhui Zhifei Longcom Biopharmaceutical Co Ltd |
Beijing Chao-Yang Hospital, The Second Affiliated Hospital, Chongqing Medical University |
China |
2020-06-22 |
2021-09-20 |
NCT04445194, NCV-I-HEALTHY |
Phase 1 Clinical |
Not yet recruiting |
1 |
14 Months |
50 |
Hong Ren, master |
2020-06-25 |
| Measles Vaccine: Is There a Protective Role in COVID-19 Pandemic? |
Coronavirus disease 19 infection |
measles vaccine alone |
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Ain Shams University |
|
Egypt |
2020-07-01 |
2020-11-01 |
FMASU P31A/ 2020, NCT04445610 |
Phase Not Applicable |
Not yet recruiting |
0 |
4 Months |
50 |
Amira Al Balakosy, M.D, Amira Al Balakosy, MD |
2020-06-25 |
| A clinical study to assess the benefits of measles, mumps, rubella (MMR) vaccine as a protection against COVID-19 |
Coronavirus disease 19 infection |
MMR vaccine alone |
|
|
American Society for Microbiology |
|
US |
|
|
|
Phase Not Applicable |
Planned |
1 |
|
|
Fidel, Noverr |
2020-06-25 |
| ANTI-CO: Anticoagulation in Patients Suffering From COVID-19 Disease - The ANTI-CO Trial |
Coronavirus disease 19 infection, Respiratory failure |
bivalirudin alone |
Factor IIa antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hamad Medical Corp |
|
Qatar |
2020-06-28 |
2021-03-28 |
ANTI-CO, MRC-05-082, NCT04445935 |
Phase 4 Clinical |
Recruiting |
1 |
9 Months |
100 |
Dr. Marcus Daniel Lance, Marcus Lance, MD, PhD, Nadir Kharma, MD, Stefan Roehrig, MD, MBA |
2020-06-25 |
| EPISODE-PS-COV: Head Pulse for Ischemic Stroke Detection Prehospital Study During the COVID-19 Pandemic |
Coronavirus disease 19 infection, Ischemic stroke |
Cranial accelerometry alone, Head pulse recording alone, MindRhythm Harmony alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
MindRhythm, Inc. |
Wayne State University |
|
2020-07-31 |
2021-06-30 |
EPISODE-PH-COVID, EPISODE-PS-COV, NCT04445493 |
Phase Not Applicable |
Not yet recruiting |
0 |
11 Months |
250 |
Lisa Distenfield, Paul Lovoi, Ph.D |
2020-06-25 |
| A study to understand differences in individual risk factors for COVID-19 |
Coronavirus disease 19 infection |
|
|
|
imaware |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
|
|
2020-06-25 |
| Study of the Treatment and Outcomes in Critically Ill Patients With COVID-19 and High Risk of Acute Kidney Injury |
Coronavirus disease 19 infection, Renal injury |
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|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Guy's & St Thomas' Hospital NHS Trust |
Harvard Medical School |
UK |
2020-06-20 |
2021-05-31 |
283672, NCT04445259 |
Phase Not Applicable |
Recruiting |
1 |
11 Months |
300 |
Marlies Ostermann, MD, PhD, Nuttha Lumlertgul, MD, PhD |
2020-06-25 |
| Unraveling the Mechanisms of Olfactory Dysfunction in COVID-19 |
Coronavirus disease 19 infection, Dysomia, Olfaction disorder |
sampling of tissue alone |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Universitaire Ziekenhuizen Leuven |
Max Planck Institute for Neurological Research |
Belgium |
2020-05-07 |
2020-06-30 |
NCT04445597, S64042 |
Phase Not Applicable |
Recruiting |
1 |
1 Month |
8 |
Laura Van Gerven, Laura Van Gerven, Doctor, Wout Backaert |
2020-06-25 |
| Mesenchymal Stromal Cell Therapy for Severe Covid-19 Infection |
Coronavirus disease 19 infection, Inflammatory disease, Viral pneumonia |
mesenchymal stromal cells alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
University of Liege |
|
Belgium |
2020-06-12 |
2022-09-30 |
NCT04445454, TJT2012 |
Phase 1/Phase 2 Clinical |
Recruiting |
1 |
27 Months |
20 |
Audrey Janssen, Benoit Misset, MD,PhD, Bernard Lambermont, MD,PhD, Gilles Darcis, MD,PhD, Michel Moutschen, MD,PhD, Nathalie Layios, MD, Yves Beguin, Yves Beguin, MD,PhD |
2020-06-25 |
| ONCOCARE-COV: Dramatic Changes in Oncology Care Pathway During COVID-19 Pandemic : The French ONCOCARE-COV Study |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire de Reims |
|
France |
2020-05-01 |
2020-12-31 |
2020AO001*, NCT04445870, ONCOCARE-COV |
Phase Not Applicable |
Recruiting |
1 |
8 Months |
100 |
Damien JOLLY, Mathias BRUGEL |
2020-06-25 |
| SCIL-COV19 PK/PD: Does subcutaneously administered anakinra achieve good penetration in blood and result in reduced inflammation in patients with SARS-CoV-19? |
Coronavirus disease 19 infection, Inflammatory disease |
anakinra alone |
Type I IL-1 receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Manchester |
|
UK |
2020-05-20 |
|
2020-001636-95, 282110, SCIL-COV19 PK/PD |
Phase 2 Clinical |
Recruiting |
1 |
|
40 |
Tim Felton |
2020-06-25 |
| Antiphospholipid Antibody (APLA) level in COVID-19 Cases |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
KIMS Hospital |
|
India |
2020-08-01 |
|
CTRI/2020/06/026118 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
80 |
Dr Rajlaxmi Sarangi |
2020-06-25 |
| CO-HOST: COVID-19 Household Transmission Study |
Coronavirus disease 19 infection |
biological sampling alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of North Carolina |
North Carolina Translational and Clinical Sciences Institute |
US |
2020-04-29 |
2020-12-31 |
20-0982, 550KR242023, CO-HOST, NCT04445233 |
Phase Not Applicable |
Recruiting |
1 |
8 Months |
400 |
Carla Cerami, MD, PhD, Christopher Basham, BS, MSc, David Wohl, MD, Jessica Lin, MD, MSCR, Jonathan Juliano, MD, MSPH |
2020-06-25 |
| Pediatrics HOT COVID-19 Database in NY Tristate |
Coronavirus disease 19 infection, Neoplasm, Neurological disease, Sickle cell anemia, Stem cell transplantation |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Columbia University |
|
US |
2020-04-30 |
2022-05-01 |
AAAT0268, NCT04445402 |
Phase Not Applicable |
Recruiting |
17 |
24 Months |
1500 |
Alex Chou, MD, Alissa Kahn, MD, Andrea Orsey, MD, Archana Sharma, Jean Sosna, MS RN, Jeffrey Lipton, MD, Jennifer Krajewski, Jennifer Levine, MD, Jessica Hochberg, MD, Joanna Pierro, MD, Katie Devine, Laura Hogan, MD, Marianna DeBenedictis, MD, Nina Kadan-Lottick, MD, Pallavi Madhusoodhan, MD, Prakash Satwani, MD, Stephen Roberts, Steven Halpern |
2020-06-25 |
| COVID-VENT: Respiratory Mechanics and Gas Exchange in Patients With COVID-19 and Hypoxemic Acute Respiratory Failure |
Coronavirus disease 19 infection, Hypoxia, Respiratory failure |
gas exchange measurement alone, respiratory mechanics measurement alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
IM Sechenov Moscow Medical Academy |
|
Russian Federation |
2020-05-01 |
2020-08-31 |
COVID-VENT, COVID-VENT, NCT04445961 |
Phase Not Applicable |
Recruiting |
1 |
4 Months |
70 |
Andrey I Yaroshetskiy, Dr.Med.Sc., Mikhail E Politov, PhD, Pavel V Nogtev, PhD, Sergey N Avdeev, Prof, Yury D Sorokin, PhD |
2020-06-25 |
| Treatment with Omega-3 polyunsaturated fatty acids in COVID-19 patients: A single-blind, randomized, placebo-controlled, feasibility study |
Coronavirus disease 19 infection, Inflammatory disease |
Omegaven alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Karolinska University Hospital |
Swedish Heart Lung Foundation, Swedish Research Council |
Sweden |
2020-05-29 |
|
2020-002293-28 |
Phase 2 Clinical |
Recruiting |
1 |
|
20 |
Co-ordinating investigator |
2020-06-25 |
| Phase II, randomized, controlled, open-label study of Pegylated IFN alfa-2b with SARS-CoV-2 |
Coronavirus disease 19 infection |
Pegylated IFN alfa-2b alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Zydus-Cadila Group |
|
India |
2020-07-10 |
|
CTRI/2020/06/026087, PEGI.20.002 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
40 |
Dr Anuja Pandit, Dr Kevinkumar Kansagra |
2020-06-25 |
| An interventional study to access the effect of Homoeopathic medicine Arsenicum album 30 C as a prohylaxis in high risk population exposed to COVID-19 |
Coronavirus disease 19 infection |
Arsenicum album 30 C alone |
|
Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Ministry of Ayush |
|
India |
2020-06-26 |
|
CTRI/2020/06/026056 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
5000 |
Dr Tapan Nath, Prof PK Goswami |
2020-06-25 |
| CovidImmunEye: Immune Status SARS-CoV-2 in a Sample of a Tertiary Eye Health Centre |
Coronavirus disease 19 infection |
ELISA test alone, Rapid test alone |
|
Healthy volunteers accepted |
University Hospital Tubingen |
Klinikum rechts der Isar der Technischen Universitaet Muenchen |
Germany |
2020-05-13 |
2020-08-31 |
292/2020BO2, CovidImmunEye, NCT04446338 |
Phase Not Applicable |
Recruiting |
2 |
3 Months |
300 |
Focke Ziemssen, Focke Ziemssen, MD, Tarek Bayyoud, MD |
2020-06-25 |
| An interventional study to access the effect of Ayurvedic medicine ASA-20 as a prohylaxis in high risk population exposed to COVID-19 |
Coronavirus disease 19 infection |
ASA-20 alone |
|
Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Ministry of Ayush |
|
India |
2020-06-26 |
|
CTRI/2020/06/026055 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
5000 |
Dr Sikha Lekharu, Prof Dr P K Goswami |
2020-06-25 |
| A phase II, randomized, controlled, multicenter to evaluate the safety, tolerability, and effectiveness of OT-101 in combination with standard of care (SoC) in hospitalized COVID-19 patients |
Coronavirus disease 19 infection |
standard of care (SoC) alone, trabedersen alone |
TGFB2 gene inhibitor |
|
Mateon Therapeutics Inc |
IQVIA Holdings Inc |
|
|
|
|
Phase 2 Clinical |
Planned |
0 |
|
|
|
2020-06-25 |
| PARTISAN: Prasugrel in Severe COVID-19 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
prasugrel alone |
P2Y12 purinoceptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Azienda Ospedaliera Universitaria Integrata Di Verona |
Universita degli Studi di Milano |
Italy |
2020-07-31 |
2021-01-31 |
MGI-COVID-19-PRASUGREL, NCT04445623, PARTISAN |
Phase 3 Clinical |
Not yet recruiting |
1 |
6 Months |
128 |
Marco Cattaneo, Professor, Pietro Minuz, Professor |
2020-06-25 |
| ILOCOVID: Inhaled Iloprost for Suspected COVID-19 Respiratory Failure |
Coronavirus disease 19 infection, Hypoxia, Respiratory failure |
iloprost (inhaled nebulizer formulation, pulmonary hypertension), Bayer Schering/Actelion alone |
PGI2 agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hamad Medical Corp |
|
Qatar |
2020-05-23 |
2021-05-31 |
ILOCOVID, MRC-05-026, NCT04445246 |
Phase 2 Clinical |
Recruiting |
1 |
12 Months |
40 |
Ali AitHssain, MD, Nadir Kharma, MD |
2020-06-25 |
| A Study of LAM-002A for the Prevention of Progression of COVID-19 |
Coronavirus disease 19 infection |
apilimod dimesylate (capsule, B-cell non-Hodgkins lymphoma/Chronic lymphocytic leukemia/amyotrophic lateral sclerosis), AI Therapeutics alone |
FYVE finger phosphoinositide kinase inhibitor, IL-12 receptor antagonist, IL-23 antagonist, Transcription factor EB stimulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
AI Therapeutics |
Yale University |
US |
2020-06-29 |
2021-01-31 |
LAM-002A-CVD-CLN01, NCT04446377 |
Phase 2 Clinical |
Not yet recruiting |
1 |
7 Months |
142 |
Charles Dela Cruz, MD, Ph.D, Peter Young, PhD |
2020-06-25 |
| Ivermectin in Treatment of COVID-19 |
Coronavirus disease 19 infection |
ivermectin alone, standard of care alone |
Chloride channel modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Zagazig University |
|
Egypt |
2020-05-31 |
2020-08-15 |
NCT04445311, ZU-IRB-6151/31-5-2020 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
2 Months |
100 |
Waheed Shouman, Waheed Shouman, MD |
2020-06-25 |
| VIRCO: An Adaptive, Randomized, Placebo-Controlled, Phase II Trial of Antivirals for COVID-19 Infection |
Coronavirus disease 19 infection |
favipiravir alone, usual standard of care alone |
RNA polymerase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Bayside Health |
|
|
2020-07-31 |
2020-11-30 |
66223, NCT04445467, VIRCO |
Phase 2 Clinical |
Not yet recruiting |
0 |
4 Months |
190 |
James McMahon, Janine Roney |
2020-06-25 |
| Short Term Corticosteroids in SARS-CoV2 Patients |
Coronavirus disease 19 infection, Hypoxia, Viral pneumonia |
dexamethasone alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Miriam Hospital |
|
US |
2020-04-01 |
2020-05-31 |
20-027, NCT04445506 |
Phase Not Applicable |
Completed |
1 |
2 Months |
50 |
Kwame Dapaah-Afriyie, MD |
2020-06-25 |
| Experimental Expanded Access Treatment With Convalescent Plasma for the Treatment of Patients With COVID-19 |
Coronavirus disease 19 infection, Respiratory failure |
convalescent COVID-19 plasma alone |
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Massachusetts, Worcester |
|
US |
|
|
H000020420, NCT04445207 |
Phase Not Applicable |
Recruiting |
1 |
|
|
Cara Gregoire, Jonathan Gerber, Jonathan Gerber, MD, Principal Investigator |
2020-06-25 |
| A study to improve the resistance against Covid-19 illness with the help of Homoeopathic remedies |
Coronavirus disease 19 infection |
homoeopathic medicine therapy alone |
|
Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Father Muller Homoeopathic Medical College |
|
India |
2020-07-01 |
|
CTRI/2020/06/026045 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
800 |
Dr Dilip B Dikshit, Dr M K Kamath |
2020-06-25 |
| Oral Fluid Sars-CoV-2 Ab Rapid test |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Asian Healthcare Foundation |
|
India |
2020-07-04 |
|
CTRI/2020/06/026044, OFST19 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Naveen Chander Reddy P, Sasikala Mitnala, Vishnupriya Rao Paturi |
2020-06-25 |
| DAMPEN COVID: Phase II Trial Using rhDNase to Reduce Mortality in COVID-19 Patients With Respiratory Failure |
Coronavirus disease 19 infection, Respiratory failure |
dornase alfa alone |
Deoxyribonuclease I stimulator, Deoxyribonuclease stimulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of South Alabama |
|
US |
2020-04-28 |
2020-07-31 |
DAMPEN COVID, NCT04445285, USAH 1002 000 |
Phase 2 Clinical |
Recruiting |
1 |
3 Months |
44 |
Jon D Simmons, M.D., Jon Simmons, Jon Simmons, M.D., Wendy Blount, RN, MSN |
2020-06-25 |
| The Effect of Inspiratory muscle training in patients with COVID-19 |
Coronavirus disease 19 infection |
Inspiratory muscle training device alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Shahid Beheshti University of Medical Sciences, Laser Application in Medical Sciences Research Center |
|
Iran |
2020-07-22 |
|
IR.SBMU.NRITLD.REC.1399.088, IRCT20200611047727N1 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
40 |
Atefeh Fakharian, Maryam Mirenayat, Saba Karimzade |
2020-06-25 |
| HERD: Protection of Health Workers Against COVID-19 |
Coronavirus disease 19 infection, Respiratory disease |
Previfenon alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
MELISA Institute Genomics & Proteomics Research SpA |
Universidad Austral De Chile |
Chile |
2020-07-30 |
2020-11-30 |
HERD, MEL109042020, NCT04446065 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
4 Months |
524 |
Cristian Vargas, MD, Elard Koch, PhD, Head of Reserach, Elard S Koch, PhD, Miguel A Bravo, MPH |
2020-06-25 |
| A diagnostic study comparing different tests for the diagnosis of COVID-19 |
Coronavirus disease 19 infection |
RT-PCR alone, nasopharyngeal swab test alone, serological test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
IRCCS Sacro Cuore Don Calabria hospital |
Ministero della Salute |
Italy |
2020-02-26 |
2020-05-25 |
ISRCTN13990999 |
Phase Not Applicable |
Completed |
1 |
3 Months |
400 |
Prof Bisoffi |
2020-06-25 |
| COVID-19 (SARS-CoV-2) in Urine and Semen |
Coronavirus disease 19 infection, Genital tract infection |
PCR test alone |
|
Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universita degli Studi di Firenze |
Azienda Ospedaliera Careggi |
Italy |
2020-07-12 |
2020-08-12 |
17104_OSS/2020, NCT04446169 |
Phase Not Applicable |
Recruiting |
0 |
1 Month |
50 |
Alberto Antonelli, MD, Alessandro Bartoloni, Prof, Arcangelo Sebastianelli, MD, Claudia Zaccaro, MD, Filippo Lagi, MD, Gian Maria Rossolini, Prof, Mauro Gacci, MD, Saverio Giancane, MD, Sergio Serni, Prof, Silvia Benemei, PhD, Simona Pollini, MD, Simone Morselli, Simone Morselli, MD |
2020-06-25 |
| ECMO-SL-CoV-2: Bicentric Study on the Use of ECMO-VV or VA for Severe ARDS Associated With SARS-CoV-2 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
veno-arterial extracorporeal membrane oxygenation therapy alone, veno-venous extracorporeal membrane oxygenation therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital of Strasbourg |
|
France |
2020-06-18 |
2020-07-18 |
7904, ECMO-SL-CoV-2, NCT04446286 |
Phase Not Applicable |
Recruiting |
0 |
1 Month |
50 |
Anne OLLAND, MD, PhD, Bart MEYNS, MD, PhD, Jean-Philipe MAZZUCOTELLI, MD, PhD, Leen VERCAEMST, MD, Marc PUYRAVEAU, MD, Marion VILLARD, MD, Pierre-Emmanuel FALCOZ, MD, PhD, Saïd CHAYER, PhD, HDR |
2020-06-25 |
| A Study of Cell Therapy in COVID-19 Subjects With Acute Kidney Injury Who Are Receiving Renal Replacement Therapy |
Coronavirus disease 19 infection, Renal injury |
SBI-101 alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sentien Biotechnologies |
|
|
2020-08-31 |
2021-07-31 |
NCT04445220, SBI-101-02 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
0 |
11 Months |
24 |
Brian Miller |
2020-06-25 |
| PLATINA trial: Plasma therapy in corona patients (Severe COVID-19) |
Coronavirus disease 19 infection |
Convalscent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Government Medical College, Nagpur |
|
India |
2020-06-25 |
|
CTRI/2020/06/026123, PLATINA trial |
Phase 2 Clinical |
Not yet recruiting |
16 |
|
472 |
Dr Anita Bandichhode, Dr Anita Basavaraj, Dr Baba Yelke, Dr D P Bhurke, Dr Deepak Shejwal, Dr Mahendrakumar V Bansode, Dr Maroti Karale, Dr Minakshi Bhattacharya, Dr Prasad Potdukhe, Dr Radha Munje, Dr Rohidas Borse, Dr Sanjay Chawhan, Dr Sheshrao S Chavan, Dr Sunita Ade, Dr Sushant Meshram, Dr Vidya Nagar, Dr Vijay Gaikwad |
2020-06-25 |
| Safety and Immunogenicity Study of GX-19, a COVID-19 Preventive DNA Vaccine in Healthy Adults |
Coronavirus disease 19 infection |
GX-19 alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Genexine Co Ltd |
|
South Korea |
2020-06-17 |
2022-06-17 |
GX-19-HV-001, NCT04445389 |
Phase 1/Phase 2 Clinical |
Recruiting |
0 |
24 Months |
190 |
Jun Yong Choi, MD, Wonjin Lee, B.S., Yoon-Jeong Choi, M.S., Young Goo Song, MD |
2020-06-25 |
| To Understand Knowledge and Compliance of Hydroxychloroquine Prophylaxis among Health Care Workers during COVID-19 pandemic |
Coronavirus disease 19 infection |
hydroxychloroquine alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Sanjay Gandhi Postgraduate Institute of Medical Sciences |
|
India |
2020-07-04 |
|
CTRI/2020/06/026121 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
175 |
Dr Mohan Gurjar |
2020-06-25 |
| Changes in smell and taste as clinical presentation in patients with mild to moderate Coronavirus disease |
Coronavirus disease 19 infection, Dysomia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kalinga Institute of Medical Sciences |
|
India |
2020-06-24 |
|
CTRI/2020/06/026122 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
250 |
Dr Pradipt Ranjan Sahoo |
2020-06-25 |
| Multicenter, open, prospective, randomized, comparative study to study the safety and efficacy of the drug Remdeform (INN: remdesivir), lyophilisate for the preparation of a solution for intravenous administration, 100 mg (Farmasintez JSC, Russia) as part of complex therapy with patients hospitalized with COVID-19 |
Coronavirus disease 19 infection |
remdesivir alone |
COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator |
|
Pharmasyntez |
|
Russian Federation |
2020-06-22 |
2021-01-01 |
REMVR-2020/I |
Phase 3 Clinical |
Status not specified |
16 |
6 Months |
300 |
|
2020-06-24 |
| Clinical Improvement and COVID-19 Pneumonia |
Coronavirus disease 19 infection, Tachypnea, Viral pneumonia |
ozone autohemotherapy alone, standard treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
L'Institut d Investigacio Biomedica de Girona |
|
Spain |
2020-03-20 |
2020-05-26 |
COVID NETWORKING GROUP, NCT04444531 |
Phase Not Applicable |
Completed |
1 |
2 Months |
18 |
Marc Vives |
2020-06-25 |
| AGMFMSS: Alterations of Gut Microbiome in the Frontline Medical Staff Under the Stress |
Acute stress disorder, Coronavirus disease 19 infection |
16S rRNA sequencing alone, PCR alone, fecal sampling alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
The First Affiliated Hospital of Xi'an Jiaotong University |
|
China |
2020-06-22 |
2020-08-30 |
AGMFMSS, NCT04443075, XJTU1AF2020LSK-022 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
180 |
Fengjie Gao, M.M., Xiancang Ma, M.D. |
2020-06-24 |
| REHCOVER: Reassessement After Hospitalization for Sars-COV-2 Disorder |
Cardiovascular disease, Coronavirus disease 19 infection, Fibrosis, Liver disease, Metabolic disorder, Neurological disease, Psychiatric disorder, Renal disease, Respiratory failure |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital, Montpellier |
|
France |
2020-06-23 |
2021-06-25 |
NCT04443257, RECHMPL20-340, REHCOVER |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
200 |
Camille ROUBILLE, MD, Camille Roubille, MD |
2020-06-24 |
| COVID-19 Vaccine (ChAdOx1 nCoV-19) Trial in South African Adults With and Without HIV-infection |
Coronavirus disease 19 infection, Respiratory tract infection |
AZD-1222 alone |
COVID19 Spike glycoprotein modulator |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
University of Witwatersrand |
Bill & Melinda Gates Foundation, Medical Research Council Of South Africa MRC, University of Oxford |
South Africa |
2020-06-30 |
2021-12-31 |
CHADOX1 NCOV-19-ZA-PHI/II, NCT04444674 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
6 |
18 Months |
2000 |
Clare L Cutland, MBBCH, PhD, Erica Lazarus, MBCHB, Keertan Dheda, MD, PhD, Lee Fairlie, MD, Shabir A Madhi, MD, PhD, Shaun Barnabas, MD, PhD, Sherman Padayachee, MD, Thabile Msomi |
2020-06-24 |
| Efficacy and Safety of Anti-HCV Drugs in the Treatment of SARS-COV-2 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
Variable regimens including daclatasvir , hydroxychloroquine , sofosbuvir |
Hepatitis C virus NS5B polymerase inhibitor, Hepatitis C virus protein NS5A inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Cairo University |
|
Egypt |
2020-07-31 |
2020-12-31 |
CUKA-003, NCT04443725 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
5 Months |
100 |
Gamal Esmat |
2020-06-25 |
| Characterizing the Perioperative Epidemiology of SARS-CoV-2 (COVID-19) Spread for Quality Improvement of Perioperative Infection Control Program |
Coronavirus disease 19 infection |
PathTrac (RDB Bioinformatics) collection kit alone, UV-C (Helios, Surfacide) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Iowa |
|
US |
2020-07-01 |
2020-08-31 |
202005391, NCT04443803 |
Phase Not Applicable |
Not yet recruiting |
1 |
2 Months |
9 |
Randy Loftus, Randy W Loftus, MD |
2020-06-24 |
| Effects of COVID-19-Induced Deconditioning After Long-term High-Intensity Resistance Exercise |
Coronavirus disease 19 infection, Osteopenia, Osteoporosis, Sarcopenia |
high-intensity resistance exercise alone |
|
Male, Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Erlangen-Nurnberg Medical School |
Friedrich-Alexander-Universitaet Erlangen-Nuernberg |
Germany |
2020-06-10 |
2020-12-31 |
FROST-FU, NCT04444661 |
Phase Not Applicable |
No longer recruiting |
1 |
6 Months |
21 |
Wolfgang Kemmler, PhD |
2020-06-24 |
| Preeclampsia-like Syndrome Induced by COVID-19: Is it a Real Public Health Issue in Pregnancy During the Pandemic? |
Coronavirus disease 19 infection, Pre-eclampsia |
PCR test alone, lung ultrasound alone |
|
Female, Young Adults (18-44 yrs) |
Zeynep Kamil Maternity and Pediatric Research and Training Hospital |
|
Turkey |
2020-03-15 |
2020-07-10 |
70/2020, NCT04443140 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
100 |
Resul Karakus, MD, Resul Karakuş |
2020-06-24 |
| Predictors of Mental Well-being During the COVID-19 Pandemic |
Coronavirus disease 19 infection, Psychiatric disorder |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Oslo |
Modum Bad |
Norway |
2020-06-22 |
2020-07-13 |
NCT04443699, REK125510-12 |
Phase Not Applicable |
Not yet recruiting |
3 |
|
4000 |
Hoffart Hoffart, PhD, Omid Ebrahimi, Double PhD Candidate, Sara Ebling, Cand.psychol. stud., Sverre Urnes Sverre Urnes, PhD |
2020-06-25 |
| Glycine Supplement for Severe COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
glycine alone, habitual treatment alone |
|
|
Instituto Nacional de Enfermedades Respiratorias |
|
Mexico |
2020-06-22 |
2021-06-30 |
C40-20, NCT04443673 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
82 |
Alejandra R Báez-Saldaña, MD, Cristóbal Guadarrama-Pérez, MD, David Ibarra-Villarreal, MD, Jaime Chávez-Alderete, PhD, Justino Regalado-Pineda, MD, Mario H Vargas, MSc, Mario H. Vargas, MD, MSc |
2020-06-25 |
| Information Sources and Their Relationship to Depressive and Anxiety Symptoms During the COVID-19 Pandemic: A Network Study |
Anxiety disorder, Coronavirus disease 19 infection, Depression |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Oslo |
Modum Bad |
Norway |
2020-06-22 |
2020-07-13 |
NCT04444336, REK125510-16 |
Phase Not Applicable |
Not yet recruiting |
2 |
|
4000 |
Asle Hoffart, PhD, Omid Ebrahimi, Double PhD Candidate, Omid V. Ebrahimi, Double PhD Candidate, Sverre Urnes Johnson, PhD |
2020-06-25 |
| A phase I clinical trial of SARS-CoV-2 protein subunit vaccine for COVID-19 |
Coronavirus disease 19 infection |
SARS-CoV-2 protein subunit vaccine (COVID-19), Chongqing Zhifei Biological Products/ Institute of Microbiology, Chinese Academy of Sciences alone |
COVID19 Spike glycoprotein modulator |
|
Institute of Microbiology, CAS |
Anhui Zhifei Longcom Biopharmaceutical Co Ltd |
China |
|
|
|
Phase 1 Clinical |
Not yet recruiting |
1 |
|
|
|
2020-06-24 |
| Mesenchymal Stem Cell Infusion for COVID-19 Infection |
Coronavirus disease 19 infection, Multiple organ failure, Respiratory failure, Septic shock, Viral pneumonia |
Standard care alone, mesenchymal stem cells alone |
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Armed Forces Bone Marrow Transplant Center |
Pak Emirates Military Hospital |
Pakistan |
2020-05-01 |
2020-09-30 |
NCT04444271, NIBMT-MSC-COVID-2020 |
Phase 2 Clinical |
Recruiting |
1 |
5 Months |
20 |
Ghassan Umair Shamshad, FCPS, Jahanzeb ur Rehmen, FCPS, Mehreen Ali Khan, FCPS, Qamar Chaudhry, FCPS, MCPS, Qamar Un Nisa Chaudhry, FCPS, Qamar un nisa Chaudhry, Raheel Iftikhar, Raheel iftikhar, FCPS, Syed Kamran Mahmood, FCPS, Tariq Azam Khattak, FCPS, Tariq Ghafoor, FCPS, raheel S iftikhar, FCPS,FACP, raheel iftikhar, FCPS |
2020-06-25 |
| Antibody Responses in Contacts of COVID-19 Patients |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assiut University |
|
Egypt |
2020-06-15 |
2020-09-30 |
ASSIUT13, NCT04444310 |
Phase Not Applicable |
No longer recruiting |
1 |
3 Months |
100 |
|
2020-06-25 |
| BIBS: Brain Imaging in Babies Study |
Attention deficit hyperactivity disorder, Autism, Central nervous system development disorder, Coronavirus disease 19 infection |
MRI alone, traditional behavioural assessments alone |
|
Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
King's College London Business Ltd |
|
UK |
2013-04-05 |
2023-12-31 |
BIBS, IRAS: 108997, REC 12/LO/2017, NCT04443179 |
Phase Not Applicable |
Recruiting |
1 |
128 Months |
790 |
Dr Grainne McAlonan, Gráinne McAlonan, PhD |
2020-06-25 |
| Sequelae of Sars-CoV-2 Infections |
Coronavirus disease 19 infection, Viral pneumonia |
computer tomography alone, echocardiography alone, electrocardiography alone, pneumologic test alone, spiroergometry alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Giessen |
|
Germany |
2020-05-20 |
2023-12-31 |
NCT04442789, SECOV |
Phase Not Applicable |
Recruiting |
1 |
43 Months |
30 |
Khodr Tello, MD, Ulrich Matt, MD, PhD |
2020-06-25 |
| Loneliness During Strict and Lifted Social Distancing Protocols Against the COVID-19 Pandemic |
Anxiety disorder, Coronavirus disease 19 infection, Depression, Psychiatric disorder |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Modum Bad |
University of Oslo |
Norway |
2020-06-22 |
2020-07-13 |
802810-1, NCT04444115 |
Phase Not Applicable |
Not yet recruiting |
2 |
|
10084 |
Asle Hoffart, Asle Hoffart, PhD, Omid Ebrahimi, Cand Psychol, Sverre Urnes Johnson, PhD |
2020-06-24 |
| The effects of self-care cellphone application on stress, anxiety and depression among admitted patients with COVID-19 |
Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression |
mobile-based application alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Mashhad University of Medical Sciences |
|
Iran |
2020-04-26 |
|
IR.MUMS.REC.1399.118, IRCT20170922036314N4 |
Phase 3 Clinical |
Recruiting |
1 |
|
112 |
Dr. Mahnaz Amini, Shokoufeh Aalaei, aalaei shokoufeh |
2020-06-25 |
| Status and Predictors of Mental Health Symptoms Among Migrants and Refugees During the COVID-19 Pandemic |
Anxiety disorder, Coronavirus disease 19 infection, Depression |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Oslo |
Modum Bad |
Norway |
2020-06-22 |
2020-07-13 |
NCT04443764, REK125510 (8) |
Phase Not Applicable |
Not yet recruiting |
2 |
|
287 |
Asle Hoffart, PhD, KariAnne Vrabel, PhD, Omid Ebrahimi, Mr, Sverre Urnes Johnson, Sverre Urnes Johnson, PhD |
2020-06-25 |
| COST-HD: Effect Of Covid-19 On Mental Health In Syrian And Turkish Maintenance Hemodialysis Patients |
Coronavirus disease 19 infection, Depression, Renal disease |
Beck Depression Inventory (BDI) alone, hemodialysis alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sisli Etfal Hospital |
|
Turkey |
2020-04-17 |
2020-05-01 |
200620, COST-HD, NCT04444557 |
Phase Not Applicable |
Completed |
1 |
|
97 |
Mustafa Sevinc, MD, Nuri Baris Hasbal |
2020-06-25 |
| Screening for Patients Admitted to Ain-Shams University Hospitals for SARS-COV-2 (COVID19) |
Coronavirus disease 19 infection |
RT-PCR test alone |
|
|
Ain Shams University |
|
Egypt |
2020-05-29 |
2021-12-01 |
FMASU P29 /2020, NCT04443712 |
Phase Not Applicable |
Recruiting |
1 |
18 Months |
1900 |
Fatma Soliman E Ebeid, Samia Girgis |
2020-06-24 |
| Do Network Centrality Predict Overall Depression Symptom Reduction With Lifting of Social Distancing Protocols? |
Coronavirus disease 19 infection, Depression |
social distancing alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Modum Bad |
University of Oslo |
Norway |
2020-06-22 |
2020-07-13 |
802810-2, NCT04444713 |
Phase Not Applicable |
Not yet recruiting |
2 |
|
10084 |
Asle Hoffart, PhD, Omid Ebrahimi, CandPsychol, Sverre Urnes Johnson, PhD |
2020-06-24 |
| Conjunctival Swab versus Nasopharyngeal Swab in Patients With COVID-19 |
Coronavirus disease 19 infection |
conjunctival swab test alone, nasopharyngeal swab test alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Medizinische Universität Innsbruck |
|
Austria |
2020-06-17 |
2021-03-31 |
1104/2020, NCT04444596 |
Phase Not Applicable |
Recruiting |
1 |
9 Months |
100 |
Claus Zehetner, Dr, Claus Zehetner, Dr., Teresa Rauchegger, Dr, Teresa Rauchegger, Dr. |
2020-06-24 |
| INTENSIVE: Registry on NEN Patients and COVID-19 |
Coronavirus disease 19 infection, Neuroendocrine tumor |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
European Institute of Oncology |
|
Italy |
2020-06-15 |
2020-12-15 |
IEO-1291, INTENSIVE, NCT04444401 |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
50 |
Cristina Mazzon, Ph.D., Darina Tamayo, PharmSC., Darina Tamayo, PharmSc, Francesca Spada, MD, PhD, Lorenzo Gervaso, MD, Nicola Fazio, M.D., Ph.D., Nicola Fazio, MD, PhD |
2020-06-25 |
| RAPID-BRAZIL: A Pragmatic, Randomized, Controlled Trial of Therapeutic Anticoagulation Versus Standard Care as a Rapid Response to COVID-19 Pandemic |
Coronavirus disease 19 infection, Thromboembolism |
enoxaparin sodium alone |
Low molecular weight heparin |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo |
St Michaels Hospital, University of Vermont Medical Center |
Brazil |
2020-06-25 |
2020-12-31 |
CAAE: 33109220.7.0000.0068, NCT04444700, RAPID-BRAZIL |
Phase 3 Clinical |
Recruiting |
1 |
6 Months |
462 |
Elnara M Negri, MD, PhD, Hassan Rahhal, MD, Heraldo P de Souza, MD, PhD, Peter Juni, MD, FESC |
2020-06-25 |
| LapCoVIDSurg: COVID 19: Is SARS-CoV-2 Contaminating Surgical Aerosols From Laparoscopy and Open Abdominal Surgery? |
Coronavirus disease 19 infection |
GeneXpert (Roche) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Basel |
|
Switzerland |
2020-08-31 |
2021-02-28 |
052020, LapCoVIDSurg, NCT04444687 |
Phase Not Applicable |
Not yet recruiting |
1 |
6 Months |
20 |
Fabian Haak, Marco von Strauss und Torney |
2020-06-24 |
| Chloroquine Phosphate Prophylactic Use in Health Personnel Exposed to COVID-19 Patients |
Coronavirus disease 19 infection |
Plasmodin (chloroquine phosphate) alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
ISSSTE Centro Medico Nacional 20 de Noviembre |
|
Mexico |
2020-06-22 |
2020-11-30 |
01, NCT04443270 |
Phase 1 Clinical |
Not yet recruiting |
1 |
5 Months |
200 |
Alberto H De la Vega-Bravo, MD, Alejandro Alanis-Vega, MD, Carlos A Delgado-Quintana, MD, Eduardo Soei-Sarmiento, BsC, Fedra Irazoque-Palazuelos, MD, Fidel Cerda-Tellez, MD, Joel Vargas-Hernández, MD, Juan A Pineda-Juárez, PhD, Juan A Suárez-Cuenca, MD, PhD, Luis Montiel-López, MD, MSc, Maribel Santosbeña-Lagunes, MD, Maricela Escarela-Serrano, MD, María C Méndez-Vidrio, MD, Mireya Rodríguez-Martínez, MD, Paul Mondragón-Terán, PhD, Ricardo P Vázquez-Alvarado, MD, Sandra Muñoz-López, MD, MSc, Sofía L Alcaraz-Estrada, PhD |
2020-06-25 |
| Nitric Oxide Releasing Solution to Treat and Prevent Exacerbation of Mild COVID-19 Infection |
Coronavirus disease 19 infection |
nitric oxide-based antiviral formulation (nasal spray/nasopharyngeal flush, COVID-19), Sanotize Research and Development alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
SaNOtize Research and Development Corp |
|
Canada |
2020-09-30 |
2021-07-31 |
COVID-IND-01, NCT04443868 |
Phase 2 Clinical |
Not yet recruiting |
1 |
10 Months |
300 |
Chris Miller, Ph.D., Jeremy Road, MD |
2020-06-25 |
| IMPReSSION: Improving Cardiovascular Risk Stratification Using T1 Mapping in General population |
Cardiovascular disease, Coronavirus disease 19 infection |
T1 mapping alone, T2 mapping alone, cardiovascular magnetic resonance alone, gadobutrol plus gadolinium |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Johann Wolfgang Goethe-Universitat Frankfurt am Main |
Johannes Gutenberg Universitat Mainz, Kerckhoff-Klinik GmbH, University Hospital Ulm |
Germany |
2016-11-15 |
2026-11-15 |
IMPRESSION STUDY, IMPReSSION, NCT04444128 |
Phase Not Applicable |
Recruiting |
3 |
120 Months |
3000 |
Andreas Rolf, MD, Franziska Weis, Philip Wenzel, MD, Valentina O Puentmann, MD, PhD, Valentina Puentmann |
2020-06-25 |
| Insomnia After the COVID-19 Pandemic |
Anxiety disorder, Coronavirus disease 19 infection, Depression, Insomnia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Oslo |
Modum Bad |
Norway |
2020-06-22 |
2020-07-13 |
NCT04443361, REK125510 (7) |
Phase Not Applicable |
Not yet recruiting |
2 |
|
5000 |
Asle Hoffart, PhD, Omid Ebrahimi, Mr, Sverre Urnes Johnson, PhD |
2020-06-24 |
| Phase I/II study of COVID-19 DNA vaccine (AG0301-COVID19) in healthy adults |
Coronavirus disease 19 infection |
SARS-CoV-2 DNA vaccine (coronavirus infection), AnGes/Osaka University alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
AnGes MG Inc |
Japan Medical Association |
Japan |
2020-06-25 |
2021-07-31 |
JapicCTI-205328 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
13 Months |
30 |
Anges Co., Ltd. |
2020-06-25 |
| SeroCoV-HUS: Seroprevalence of SARS-CoV-2 in Strasbourg University Hospital, Strasbourg, France (COVID-19) |
Coronavirus disease 19 infection |
COVID-19 BSS reference SW40005 diagnostic kit (Biosynex) alone, EDI Novel Coronavirus COVID-19 ELISA IgG kit (Epitope Diagnostics Inc) alone, ELISA alone, lateral flow assay-immuno-chromatographic test (LFA-ICT) alone, serological test alone, seroneutralization test alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hopitaux Universitaires de Strasbourg |
|
France |
2020-04-17 |
2021-08-31 |
7782, NCT04441684, SeroCoV-HUS |
Phase Not Applicable |
Recruiting |
1 |
16 Months |
1800 |
Aleksandra NADAJ-PAKLEZA, MD, Catherine MUTTER, MD, David REY, MD PhD, Jean-Baptiste CHANSON, MD, Jérôme DE SEZE, MD PhD, Laurent KREMER, MD, Livia LANOTTE, MD, Maria GONZALEZ, MD PhD, Maria PARTISANI, MD, Marie MIELCAREK, MD, Marie-Aude SPITZ, MD, Marie-Céline FLEURY, MD, Nathalie PHILIPPI, MD, Nicolas COLLONGUES, MD, Nicolas LEFEBVRE, MD, Samira FAFI-KREMER, MD PhD, Yves HANSMANN, MD PhD |
2020-06-25 |
| Therapeutic Plasma Exchange for COVID-19-associated Hyperviscosity |
Coronavirus disease 19 infection, Vascular disease |
frozen plasma alone, therapeutic plasma exchange alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Emory University |
|
US |
2020-07-31 |
2020-10-31 |
NCT04441996, STUDY00000949 |
Phase 4 Clinical |
Not yet recruiting |
3 |
3 Months |
20 |
Cheryl Maier, MD, PhD |
2020-06-25 |
| Convalescent Plasma Therapy on Critically-ill Novel Coronavirus (COVID-19) Patients |
Coronavirus disease 19 infection, Dyspnea, Viral pneumonia |
convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Alkarkh Health Directorate-Baghdad |
|
Iraq |
2020-04-03 |
2020-06-01 |
CPT-COVID-19, NCT04441424 |
Phase 2 Clinical |
Completed |
1 |
1 Month |
49 |
Ahmed S Abdulamir, PhD |
2020-06-25 |
| Convalescent Plasma as a Possible Treatment for COVID-19 |
Coronavirus disease 19 infection |
convalescent plasma alone, convalescent plasma plus remdesivir |
COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Illinois |
|
US |
2020-05-05 |
2021-05-05 |
2020-0441, NCT04442191 |
Phase 2 Clinical |
Recruiting |
1 |
12 Months |
50 |
Jesica A Herrick, MD, Jesica A Herrick, MD, MS, Jesica Herrick, Mahesh Patel, MD, Richard Novak, MD, Sally Campbell-Lee, MD |
2020-06-25 |
| A short-term follow-up study to assess the effect of SARS-CoV-2 total antibody assay in dialysis patients with Covid-19 |
Coronavirus disease 19 infection |
SARS-CoV-2 total antibody assay (Siemens Healthineers) alone |
|
|
Ascend Clinical, Stanford University School of Medicine |
|
US |
2020-07-31 |
|
|
Phase Not Applicable |
Planned |
0 |
|
30000 |
Shuchi Anand, MD |
2020-06-25 |
| Factors Associated With Adherence to Hygiene-related Behaviors and Viral Mitigation Protocols During the COVID-19 Pandemic |
Coronavirus disease 19 infection |
hygiene-related behavior alone, viral mitigation protocol alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Oslo |
Modum Bad |
Norway |
2020-06-22 |
2020-07-13 |
NCT04442217, REK125510-11 |
Phase Not Applicable |
Not yet recruiting |
2 |
|
4000 |
Asle Hoffart, PhD, Omid V. Ebrahimi, Double PhD Candidate, Sverre Urnes Johnson, PhD |
2020-06-24 |
| Assessment of Lung Inflammation With FDG PET/CT in COVID-19 |
Coronavirus disease 19 infection, Lung inflammation |
FDG alone, computerized tomography alone, positron emission tomography alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Princesse Grace |
|
Monaco |
2020-03-27 |
2020-05-27 |
NCT04441489, PET-COVID |
Phase Not Applicable |
Completed |
1 |
2 Months |
13 |
|
2020-06-23 |
| Spatial-temporal modelling, covid-19 |
Coronavirus disease 19 infection |
spatial-temporal modelling alone |
|
|
Universiti Kebangsaan Malaysia |
|
Malaysia |
2020-07-01 |
2020-12-31 |
54919, NMRR-20-1178-54919 |
Phase Not Applicable |
Status not specified |
1 |
6 Months |
|
Prof. Mohd Talib Latif |
2020-06-25 |
| COVID-19 Serosurvey |
Coronavirus disease 19 infection |
|
|
|
National Institutes of Health Malaysia |
|
Malaysia |
2020-08-01 |
2020-10-30 |
55133, NMRR-20-1166-55133 |
Phase Not Applicable |
Not yet recruiting |
1 |
2 Months |
|
Dr Chong Zhuo Lin, Mr. Mohd Hatta Bin Abdul Mutalip |
2020-06-25 |
| Impact survey |
Coronavirus disease 19 infection |
|
|
|
Sultanah Nur Zahirah Hospital |
|
Malaysia |
2020-07-01 |
|
NMRR-20-1160-55260, NR 2020 55260 |
Phase Not Applicable |
Status not specified |
1 |
|
|
DR nandinii a/p ramasenderan |
2020-06-24 |
| Tolerability, Safety, Pharmacokinetic Profile and Immunogenicity of a Recombinant Humanized Anti-SARS-CoV-2 Monoclonal Antibody (JS-016) for Injection in Chinese Health Subjects |
Coronavirus disease 19 infection |
JS-016 alone |
COVID19 Spike glycoprotein inhibitor |
Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Asian Ancestry |
Eli Lilly & Co, Shanghai Junshi Biosciences Co Ltd |
|
China, US |
2020-06-05 |
2020-12-11 |
JS016-001-I, NCT04441918 |
Phase 1 Clinical |
Recruiting |
2 |
6 Months |
40 |
Jing Zhang, Wenhong Zhang |
2020-06-23 |
| A phase I clinical study of CDX-005 for the potential prevention of COVID-19 infection |
Coronavirus disease 19 infection |
CDX-005 alone |
|
|
Codagenix Inc |
|
|
|
|
|
Phase 1 Clinical |
Planned |
0 |
|
|
|
2020-06-24 |
| ALLOPRIME: Universal Anti-Viral Vaccine for Healthy Elderly Adults |
Coronavirus disease 19 infection |
AlloStim vaccine (Allo-priming, COVID-19), Immunovative Therapies alone |
|
Healthy volunteers accepted, Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Immunovative Therapies Ltd |
Mirror biologics, Inc |
US |
2020-07-06 |
2021-12-31 |
ALLOPRIME, MBI-001-ALLOPRIME, NCT04441047 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
17 Months |
40 |
Azriel Hirschfield, MD, Kim Demonte, Thu Bui, MHA |
2020-06-24 |
| AfriCoVER: Characterising Transmission of SARS-CoV-2 in a Peri-urban Population in Mozambique |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted |
Institute of Tropical Medicine, Belgium |
European and Developing Countries Clinical Trials Partnership, Institut de Recherche pour le Developpement (IRD), National Institute of Health, Mozambique, Universitair Medisch Centrum Utrecht |
Mozambique, Belgium |
2020-07-15 |
2021-07-14 |
AFRICOVER, AfriCoVER, NCT04442165 |
Phase Not Applicable |
Not yet recruiting |
2 |
12 Months |
15393 |
Marc-Alain Widdowson, Dr, Natacha Herssens, MSc, Yven Van Herrewege |
2020-06-25 |
| The Impact of Information Sources on Mental Health During the COVID-19 Pandemic |
Anxiety disorder, Coronavirus disease 19 infection, Depression |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Oslo |
Modum Bad |
Norway |
2020-06-22 |
2020-07-13 |
NCT04442360, REK125510-13 |
Phase Not Applicable |
Not yet recruiting |
3 |
|
4000 |
Asle Hoffart, PhD, Ole Myklebust Amundsen, Cand.Psychol Student, Omid V. Ebrahimi, Double PhD Candidate, Omid V. Ebrahimi, PhD, Sverre Urnes Johnson, PhD |
2020-06-24 |
| A phase IIa, proof-of-concept study of FSD-201 for the treatment of COVID-19 infection |
Coronavirus disease 19 infection |
palmidrol + morphine (ultramicronized, severe chronic pain), FSD Pharma alone |
Cannabinoid CB2 receptor modulator, Opioid receptor mu agonist |
|
FSD Pharma Inc |
|
|
|
|
|
Phase 2a Clinical |
Planned |
0 |
|
|
|
2020-06-23 |
| Efficacy and Safety of Nitazoxanide 600 mg to Treat Mild Ambulatory COVID-19 Patients |
Coronavirus disease 19 infection, Viral respiratory tract infection |
Standard care alone, nitazoxanide (Viranitta) alone |
|
Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Azidus Brasil |
Farmoquimica SA |
Brazil |
2020-07-31 |
2020-09-30 |
NCT04441398, NITFQM0720OR |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
2 Months |
300 |
Edimilson Migowski, MD, Luciana Ferrara, Thiago Wendel, MD |
2020-06-24 |
| FOUND: Ancillary Study to Smile Protocol NCT03654105 |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Fondazione IRCCS Istituto Nazionale Tumori |
Universita degli Studi di Milano, Universita' Degli Studi Di Parma, University of Milano-Bicocca |
Italy |
2019-07-23 |
2021-07-31 |
FOUND, INT 49/20, NCT04441814 |
Phase Not Applicable |
Recruiting |
3 |
24 Months |
960 |
Ugo Pastorino, MD |
2020-06-24 |
| Parental Stress After the Covid-19 Pandemic |
Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Oslo |
Modum Bad |
Norway |
2020-06-22 |
2020-07-13 |
NCT04442308, REK125510 (6) |
Phase Not Applicable |
Not yet recruiting |
4 |
|
1440 |
Asle Hoffart, PhD, Miriam S Johnson, PhD, Nora Paulsen Skjerdingstad, Omid Ebrahimi, Sverre Urnes Johnson, Sverre Urnes Johnson, PhD |
2020-06-25 |
| ILIAD-7-US-I: InterLeukin-7 to Improve Clinical Outcomes in Lymphopenic Patients With COVID-19 Infection |
Coronavirus disease 19 infection, Hypoxia, Lymphocytopenia, Respiratory failure |
CYT-107 alone |
IL-7 receptor agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Revimmune Inc |
Amarex Clinical Research, Washington University in St Louis |
US |
2020-06-30 |
2020-12-31 |
ILIAD-7 COVID US INFECTIOUS, ILIAD-7-US-I, NCT04442178 |
Phase 2 Clinical |
Not yet recruiting |
1 |
6 Months |
48 |
Frederique Berbille, MHSc, Michel Morre, DVM, Richard Hotchkiss, MD PhD |
2020-06-24 |
| PRIORITY: Prognostication of Oxygen Requirement in Non-severe SARS-CoV-2 Respiratory Infection |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Medecins Sans Frontieres |
International Centre For Diarrhoeal Disease Research, Bangladesh, The Mahidol Oxford Tropical Medicine Research Unit |
Bangladesh |
2020-08-01 |
2021-03-01 |
0000, NCT04441372, PRIORITY |
Phase Not Applicable |
Not yet recruiting |
1 |
7 Months |
850 |
Arjun Chandna, MD, Mikhael Yosia, MD, Mohammad Shomik, MD, Sakib Burza, PhD |
2020-06-24 |
| FamilyPEDCOVID: Study of Seroprevalence of Anti-SARS-CoV2 Among Children of Hospital Workers in AP-HP |
Coronavirus disease 19 infection |
serology test alone |
|
Healthy volunteers accepted |
Assistance Publique Hopitaux de Paris |
|
France |
2020-06-30 |
2020-09-30 |
2020-A01480-39, APHP200627, FamilyPEDCOVID, NCT04442087 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
400 |
Flore ROZENBERG, MD, PhD, Jean-Marc TRELUYER, MD, PhD, Jean-Marc Treluyer, MD, PhD, Michaela SEMERARO, MD, Solen KERNEIS, MD, Valérie JOLAINE, Master |
2020-06-25 |
| Predictors and Mechanisms of Depression and Anxiety During the COVID-19 Pandemic |
Anxiety disorder, Coronavirus disease 19 infection, Depression |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Oslo |
Modum Bad |
Norway |
2020-06-22 |
2020-07-13 |
NCT04442204, REK125510-10 |
Phase Not Applicable |
Not yet recruiting |
2 |
|
4000 |
Asle Hoffart, PhD, Omid Ebrahimi, Double PhD Candidate, Omid V. Ebrahimi, Double PhD Candidate, Sverre Urnes Johnson, PhD |
2020-06-25 |
| PsyCOVID: Ethical and Psychological Support for Health Care Professions in Intensive Care Units in the COVID-19 Pandemic Context: Adequacy With Needs and Psychological Impact Crisis and Post-crisis |
Coronavirus disease 19 infection, Psychiatric disorder |
Limesurvey platform alone, psychological interview alone, sociological interview alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire Dijon |
|
France |
2020-04-21 |
2020-11-30 |
NCT04441476, PsyCOVID, QUENOT SERI 2020 |
Phase Not Applicable |
No longer recruiting |
1 |
7 Months |
3000 |
|
2020-06-25 |
| PTSD Symptoms Among Health Workers and Public Service Providers After the COVID-19 Outbreak: A 3 Month, Follow-up |
Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Oslo |
Modum Bad |
Norway |
2020-06-22 |
2020-07-13 |
NCT04442243, REK125510 (4) |
Phase Not Applicable |
Not yet recruiting |
2 |
|
889 |
Asle Hoffart, PhD, Omid Ebrahimi, Omid Ebrahimi, Mr, Sverre Urnes Johnson, Sverre Urnes Johnson, PhD |
2020-06-25 |
| MARACOVID: Study to Evaluate the Efficacy and Safety of Maraviroc in SARS-CoV-2 Infection (COVID-19) |
Coronavirus disease 19 infection, Respiratory distress syndrome |
Standard care therapy alone, maraviroc alone |
CCR5 chemokine antagonist, CD4 agonist, HIV-1 gp120 protein inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Universitario Infanta Leonor |
GlaxoSmithKline plc, Hospital Clinic of Barcelona |
Spain |
2020-06-26 |
2020-12-20 |
2020-002011-21, MARACOVID, MARACOVID, NCT04441385 |
Phase 2 Clinical |
Not yet recruiting |
2 |
5 Months |
200 |
Berta Torres, PhD, MD, Felipe García, PhD, MD, Guillermo Cuevas, MD, Jesus Troya, MD, Montserrat Laguno, PhD, MD, Pablo Ryan, MD, Rosa María Muñoz, Victor Domínguez, MD, Víctor Domínguez, MD, Álex Soriano, PhD, MD |
2020-06-23 |
| COVID_OMICS: Identification of Predictors for the Evolution of COVID-19 Related Pneumonia by Transcriptomic and Seroproteomic |
Cardiovascular injury, Coronavirus disease 19 infection, Interstitial lung disease, Viral pneumonia |
blood sampling alone, chest x-ray alone, computed tomography alone, echocardiography alone, genome analysis alone, seroproteomic analysis alone, transcriptional analysis alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
IRCCS Policlinico San Donato |
|
Italy |
2020-03-30 |
2020-12-31 |
COVID19_OMICS, COVID_OMICS, NCT04441502 |
Phase Not Applicable |
Recruiting |
1 |
9 Months |
240 |
Ekaterina Baryshnikova, PhD, Fabio Martelli, PhD, Marco Ranucci, MD, Marco Ranucci, MD FESC, Massimiliano M Corsi Romanelli, MD PhD, Rosanna Cardani, PhD |
2020-06-25 |
| NasoVAX in Patients With Early Coronavirus Infectious Disease 2019 (COVID-19) |
Coronavirus disease 19 infection |
NasoVAX alone |
Hemagglutinin modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Altimmune Inc |
|
|
2020-06-30 |
2020-12-31 |
ALT-601-201, NCT04442230 |
Phase 2 Clinical |
Not yet recruiting |
0 |
6 Months |
96 |
Christine Orlando, Staci Steele |
2020-06-25 |
| Evaluation of a COVID-19 antibody test: What is the performance of the Panbio COVID-19 IgG/IgM rapid test device in fingerstick blood, venous whole blood, serum and plasma in adult participants? |
Coronavirus disease 19 infection |
Panbio alone |
|
|
Abbott Laboratories Ltd |
|
UK |
2020-04-06 |
2020-07-03 |
CLDG-0503, IRAS 283040, ISRCTN60400862 |
Phase Not Applicable |
No longer recruiting |
2 |
2 Months |
|
Prof T.Kennedy |
2020-06-24 |
| Parental Burnout During the COVID-19 Pandemic: Risk Factors and Predictors |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Oslo |
Modum Bad |
Norway |
2020-06-22 |
2020-07-13 |
NCT04442386, REK125510-15 |
Phase Not Applicable |
Not yet recruiting |
2 |
|
1500 |
Asle Hoffart, PhD, Miriam Sinkerud Johnson, PhD, Nora Paulsen Skjerdingstad, Cand.psychol. stud, Omid V. Ebrahimi, Double PhD Candidate, Sverre Urnes Johnson, PhD |
2020-06-24 |
| DIAMONDS: DIAMONDS-SEARCH study: Designing new tests that can diagnose the causes of fever, including COVID-19 |
Coronavirus disease 19 infection |
Personalised Molecular Signature Diagnosis alone |
|
|
Imperial College London |
|
Gambia, Taiwan, UK, Greece, Netherlands, Switzerland, Austria, Germany, Latvia, France, Spain, Italy, Nepal, Slovenia |
2020-01-01 |
2025-05-30 |
20SM5903, IRAS 278651, CPMS 45537, DIAMONDS, ISRCTN12394803 |
Phase Not Applicable |
Recruiting |
36 |
64 Months |
5000 |
Dr Federico Martinón-Torres, Prof Levin |
2020-06-24 |
| COV-IMMUNO: Immunization With IMM-101 Versus Observation for Prevention of Respiratory and Severe COVID-19 Related Infections in Cancer Patients at Increased Risk of Exposure |
Cancer, Coronavirus disease 19 infection, Lymphoma, Multiple myeloma, Respiratory tract infection, Solid tumor |
IMM-101 alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Canadian Cancer Trials Group |
ATGen Canada Inc, BioCanRx, Canadian Cancer Society, Canadian Centre for Applied Research in Cancer Control, Immodulon Therapeutics Ltd |
|
2020-07-01 |
2021-03-31 |
COV-IMMUNO, IC8, NCT04442048 |
Phase 3 Clinical |
Not yet recruiting |
0 |
9 Months |
1500 |
Auer, Chris O'Callaghan, Rebecca A Auer |
2020-06-24 |
| Difficulties in Emotion-regulation and Interpersonal Problems During and After the COVID-19 Pandemic |
Anxiety disorder, Coronavirus disease 19 infection, Depression |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Oslo |
Modum Bad |
Norway |
2020-06-22 |
2020-07-13 |
NCT04442282, REK125510 (5) |
Phase Not Applicable |
Not yet recruiting |
2 |
|
5041 |
Asle Hoffart, PhD, Jon Monsen, PhD, Ole Andrè Solbakken, PhD, Omid Ebrahimi, Mr, Sverre Urnes Johnson, PhD |
2020-06-24 |
| A trial to evaluate ciclesonide for the treatment of patients with covid-19 |
Coronavirus disease 19 infection |
ciclesonide (nasal/aerosol formulation), Covis/AstraZeneca alone |
|
|
University at Buffalo |
|
US |
2020-06-18 |
|
|
Phase 3 Clinical |
Recruiting |
1 |
|
400 |
|
2020-06-23 |
| CoVid3S: Caregiver Serological Monitoring Extended Secondarily to Patients With the SARS-CoV-2 Coronavirus |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted |
Hospices Civils De Lyon |
|
France |
2020-07-31 |
2022-01-31 |
69HCL20_0395, CoVid3S, NCT04441710 |
Phase Not Applicable |
Not yet recruiting |
4 |
18 Months |
2500 |
Antonin BAL, MD, Bruno POZZETTO, MD, François GUEYFFIER, MD, Julien LUPO, MD, Marine ALEXANDRE, Pascal FASCIA, MD |
2020-06-24 |
| NOXCOVID-1: A Phase I dose-escalation and dose-expansion study to evaluate the safety and proof-of- principle endpoints (biomarker and clinical responses)in SARS-CoV-2 infected patients |
Coronavirus disease 19 infection, Respiratory insufficiency |
idronoxil (suppository, late-stage prostate cancer/soft tissue sarcoma/cancers/COVID-19-associated diseases), Noxopharm alone |
CASP8-FADD-like regulator inhibitor, Ecto NOX disulfide thiol exchanger 2 inhibitor, Sphingosine kinase inhibitor, Sphingosine-1-phosphate receptor-1 antagonist, Stimulator of interferon genes protein stimulator, Topoisomerase inhibitor, X-linked inhibitor of apoptosis protein inhibitor |
|
Noxopharm Ltd |
|
Moldova, Republic of, Ukraine |
|
|
NOXCOVID-1 |
Phase 1 Clinical |
Planned |
2 |
|
40 |
|
2020-06-23 |
| HCW: Cross-sectional Study on Prevalence of COVID-19 Positive Cases Among The Healthcare Workers Via COVID-19 Screening Program In Sabah Women And Children Hospital |
Coronavirus disease 19 infection |
COVID-19 Screening Program alone |
|
Healthy volunteers accepted |
Sabah Women and Children's Hospital |
|
Malaysia |
2020-07-01 |
2020-10-31 |
55335, HCW, NMRR-20-1199-55335 |
Phase Not Applicable |
Status not specified |
1 |
4 Months |
|
Dr Audrey Chong Shuk Lan, Dr WONG WEI KONG |
2020-06-25 |
| Drug Utilization Review: Treatment of COVID-19 |
Coronavirus disease 19 infection |
atazanavir sulfate + ritonavir (HIV infection), Mylan Laboratories alone, chloroquine alone, favipiravir alone, hydroxychloroquine alone, interferon beta 1b alone, lopinavir + ritonavir alone, ribavirin alone, tocilizumab alone |
HIV protease inhibitor, RNA polymerase inhibitor |
|
Hospital Sungai Buloh |
|
Malaysia |
2020-06-22 |
2020-08-31 |
55117, NMRR-20-1192-55117 |
Phase Not Applicable |
Status not specified |
1 |
2 Months |
|
Ms Hannah binti Md Mahir |
2020-06-25 |
| COVID-19 in kidney transplant recipient |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Seth GS Medical College |
|
India |
2020-06-26 |
|
CTRI/2020/06/026000 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
75 |
Dr Divya Bajpai, Dr Tukaram Jamale |
2020-06-24 |
| Clinical trial of ShatPlus as an immunomodulator in adult Covid 19 positive patients |
Coronavirus disease 19 infection |
ShatPlus alone, Standard treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
BVG Life Sciences Ltd |
|
India |
2020-06-27 |
|
CTRI/2020/06/025999, MHC/CT/20-21/003 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
60 |
Dr Pawan Kumar Singh, Dr Tushar V Patil |
2020-06-24 |
| Efficacy of An Ayurvedic Preparation Raj Nirwan Bati (RNB) on symptomatic COVID-19 Patients |
Coronavirus disease 19 infection |
Raj Nirwan Bati alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Uttar Pradesh University of Medical Sciences |
|
India |
2020-06-30 |
|
CTRI/2020/06/025998 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
60 |
Dr Naresh Pal Singh, Dr Raj Kumar |
2020-06-24 |
| A Clinical Evaluation of the combination Giloy Gomutra Capsules, Asthi Churna and Kamdhenu Asava in the Management of the Pandemic- Covid-19 |
Coronavirus disease 19 infection |
Variable regimens including Asthi Churna , Giloy gaumutra , Kamdhenu Asava |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
GMERS Medical College and Hospital |
|
India |
|
|
CTRI/2020/06/025996 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
200 |
Dr Dineshchandra Pandya, Urvi Pandya |
2020-06-24 |
| Miscarriage COVID |
Coronavirus disease 19 infection |
|
|
|
Sarawak General Hospital |
|
Malaysia |
2020-06-14 |
2020-06-30 |
55402, NMRR-20-1153-55402 |
Phase Not Applicable |
Completed |
1 |
|
|
Dr. Wong Tze Cheng |
2020-06-24 |
| A phase I/II trial of plasma-derived anti-SARS-CoV-2 IgG (COVID-19), Kedrion Biopharma/Kamada for the treatment of Coronavirus disease 19 infection |
Coronavirus disease 19 infection |
plasma-derived anti-SARS-CoV-2 IgG (COVID-19), Kedrion Biopharma/Kamada alone |
|
|
Kamada Ltd |
|
Israel |
2020-09-30 |
|
|
Phase 1/Phase 2 Clinical |
Planned |
1 |
|
|
|
2020-06-23 |
| Brain Health in the Time of COVID-19 |
Cognitive disorder, Coronavirus disease 19 infection |
cognitive screening tool alone, tablet-based games alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Miro Health |
Johns Hopkins University, University of Pittsburgh |
US |
2020-06-16 |
2020-12-31 |
MIRO_001_2020, NCT04438967 |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
10000 |
Natasha Belfor, PhD, Shenly Glenn, BS |
2020-06-24 |
| Evaluation of the effect of nano micelles containing curcumin (Sina Ccurcumin) as a therapeutic supplement in patients with COVID-19 |
Coronavirus disease 19 infection |
SinaCurcumin alone, routine treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Bandare-abbas University of Medical Sciences |
|
Iran |
2020-07-05 |
|
IR.HUMS.REC.1399.174, IRCT20200611047735N1 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
40 |
Amin Reza Nikpoo, Amin Reza Nikpoor, Teymour agha mollaie |
2020-06-24 |
| Study of Use of Ayurveda Intervention (Ayush-64) in COVID 19 |
Coronavirus disease 19 infection |
AYUSH 64 alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
National Institute of Ayurveda Jaipur Rajasthan |
|
India |
2020-07-01 |
|
CTRI/2020/06/026002 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
60 |
Dr Jaykaran Charan, Dr Pankaj Bhardwaj, Prof Pawan kumar Godatwar |
2020-06-22 |
| RIVET-COV: Ivermectin in COVID |
Coronavirus disease 19 infection |
ivermectin alone |
Chloride channel modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
All India Institute of Medical Sciences |
|
India |
2020-06-25 |
|
CTRI/2020/06/026001, RIVET-COV |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
60 |
Anant Mohan |
2020-06-22 |
| CANCOV SURVEY: CANCER care in COVID-19 ERA – A survey proposed to study the treatment preference and perspectives of patients with blood cancer in a highly specialized cancer care hospital in India during COVID-19 ERA |
Acute leukemia, Chronic leukemia, Coronavirus disease 19 infection, Hematological neoplasm, Lymphoma, Multiple myeloma |
cancer-directed chemo/immune or targeted therapy alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tata Memorial Hospital |
|
India |
2020-06-15 |
|
CANCOV SURVEY, CTRI/2020/06/026039 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
213 |
Dr Avinash Bonda |
2020-06-22 |
| Pooled testing for COVID |
Coronavirus disease 19 infection |
SARS CoV-2 RT-PCR testing alone |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Centre for Biological Sciences |
|
India |
2020-06-22 |
|
CTRI/2020/06/026005 |
Phase Not Applicable |
Not yet recruiting |
3 |
|
321 |
Dasaradhi Palakodeti, Manoj Gopalkrishnan, Omshree Shetty, Priya Ranganathan, R Parthiban, Uma Ramakrishnan |
2020-06-24 |
| A follow-up study of novel coronavirus pneumonia (COVID-19) patients in Wanzhou District, Chongqing |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The second Clinical Hospital of Chongqing Medical University |
|
China |
2020-06-01 |
2020-11-01 |
ChiCTR2000033980 |
Phase Not Applicable |
Not yet recruiting |
1 |
5 Months |
67 |
Depeng Jiang, Lingfang Xu |
2020-06-24 |
| A larger phase II clinical trial of SARS-CoV-2 mRNA vaccine (COVID-19), CureVac in the prevention of coronavirus infection |
Coronavirus disease 19 infection |
SARS-CoV-2 mRNA vaccine (COVID-19), CureVac alone |
|
|
CureVac AG |
|
|
2020-10-31 |
|
|
Phase 2 Clinical |
Planned |
0 |
|
|
|
2020-06-23 |
| The Impact of a Societal Lockdown on Those With Spinal Cord and Brain Injuries |
Brain injury, Coronavirus disease 19 infection, Spinal cord injury, Stroke |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Lawson Health Research Institute |
|
Canada |
2020-06-30 |
2020-12-31 |
115999, NCT04426071 |
Phase Not Applicable |
Not yet recruiting |
1 |
6 Months |
142 |
Eldon Loh, MD, Swati Mehta, PhD |
2020-06-22 |
| Efficacy of Blood Purification Techniques on COVID-19 Pneumonia |
Coronavirus disease 19 infection, Respiratory distress syndrome |
Continuous Renal Replacement Therapy alone, Hemoperfusion alone, anti-complement filter with crrt system alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shahid Beheshti University |
|
Iran |
2020-03-20 |
2020-05-21 |
IR.SBMU.NRITLD.REC.1399.011, IRCT20150107020592N29 |
Phase 3 Clinical |
Completed |
1 |
2 Months |
12 |
Seyed Mohammad Reza Hashemian, Seyed Mohammad reza Hashemian, Seyyed Mohammadreza Hashemian |
2020-06-23 |
| A clinical study of TNX-1800 for the potential prevention of COVID-19 infection |
Coronavirus disease 19 infection |
TNX-1800 alone |
COVID19 Spike glycoprotein modulator |
|
Southern Research Institute, Tonix Pharmaceuticals Holding Corp |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-06-22 |
| A new feasibility, phase I study to test Hemopurifier in patients with SARS-CoV-2/COVID-19 |
Acute lung injury, Coronavirus disease 19 infection |
Hemopurifier alone |
|
|
Aethlon Medical Inc |
|
US |
|
|
|
Phase 1 Clinical |
Not yet recruiting |
1 |
|
40 |
|
2020-06-22 |
| COVER: Covidivermectin: Ivermectin for Treatment of Covid-19 |
Coronavirus disease 19 infection |
ivermectin alone |
Chloride channel modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ospedale Sacro Cuore don Calabria |
Istituto di Ricerche Farmacologiche Mario Negri |
Italy, Spain |
2020-06-30 |
2020-10-31 |
COVER, COVER_1, NCT04438850 |
Phase 2 Clinical |
Not yet recruiting |
7 |
4 Months |
102 |
Dora Buonfrate, Giovanni Pedrotti, Guido Celleri, José Muñoz, Luciano Attard, Spinello Antinori, Zeno Bisoffi, Zeno Bisoffi, PhD |
2020-06-23 |
| A study on the prevalence of infection in dental institutions by measuring the antibody titer to COVID-19 of the staff members of Kanagawa Dental College Medical Center |
Coronavirus disease 19 infection |
COVID-19 PCR test alone, ELISA alone, immunochromatography alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kanagawa Dental University |
|
Japan |
2020-06-22 |
|
UMIN000040733 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
300 |
Keiichi Tsukinoki, Keisuke Handa |
2020-06-23 |
| COBRA: Efficacy and Safety of VPM-1002 in Reducing SARS-CoV-2 (COVID-19) Infection Rate and Severity |
Coronavirus disease 19 infection |
VPM-1002 alone |
Listeriolysin stimulator |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The University Health Network |
Max Planck Institute for Infection Biology, Serum Institute of India Ltd, Verity Pharmaceuticals Inc |
Canada |
2020-06-14 |
2021-06-01 |
20-5413, COBRA, NCT04439045 |
Phase 3 Clinical |
Not yet recruiting |
1 |
11 Months |
3626 |
Alexandre R Zlotta, MD PhD, Cynthia Kuk, MSc, Miran Kenk, PhD |
2020-06-23 |
| FITE19: A Study to Evaluate Efficacy and Safety of PTC-299 in Hospitalized Participants With Coronavirus (COVID-19) |
Coronavirus disease 19 infection |
PTC-299 alone, Standard of care alone |
Dihydroorotate dehydrogenase inhibitor, IL-6 receptor antagonist, VEGF receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
PTC Therapeutics Inc |
|
US, Brazil, Australia, Spain, Europe |
2020-06-30 |
2021-01-30 |
2020-001872-13, FITE19, NCT04439071, PTC299-VIR-015-COV19 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
7 |
7 Months |
380 |
Patient Advocacy, Quintus Ngumah, OD, PhD |
2020-06-24 |
| Isolated During COVID-19: Effects of COVID-19's Social Restrictions on Loneliness and Psychosocial Symptomatology |
Alcoholism, Anxiety disorder, Coronavirus disease 19 infection, Depression, Drug dependence |
socially restriction alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs) |
University of Miami |
|
US |
2020-04-22 |
2020-05-11 |
20200446, NCT04440098 |
Phase Not Applicable |
Completed |
1 |
|
1008 |
Viviana E Horigian, MD |
2020-06-23 |
| COLD: COVID-19 in Patients With Chronic Liver Diseases |
Alcoholic liver disease, Autoimmune hepatitis, Coronavirus disease 19 infection, Hepatitis B virus infection, Hepatitis C virus infection, Hepatocellular carcinoma, Liver cirrhosis, Non alcoholic fatty liver disease, Primary biliary cholangitis, Primary sclerosing cholangitis |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Stanford University |
|
US |
2020-03-06 |
2021-06-30 |
55819, COLD, NCT04439084 |
Phase Not Applicable |
Recruiting |
21 |
15 Months |
1000 |
Renumathy Dhanasekaran, MD |
2020-06-23 |
| A multicenter clinical study: transmission of COVID-19 and impact on health and developmental outcomes among newborns of mothers with confirmed/suspected COVID-19 |
Coronavirus disease 19 infection |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Hubei Maternal and Child Health Hospital |
The Hong Kong Committee for UNICEF |
China |
2020-02-10 |
2020-12-31 |
ChiCTR2000033960 |
Phase 0 Clinical |
Recruiting |
10 |
10 Months |
90 |
Shiwen Xia |
2020-06-23 |
| Investigation of Fatigue, Physical Activity, Sleep Quality and Anxiety Levels |
Anxiety disorder, Coronavirus disease 19 infection, Fatigue, Multiple sclerosis |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Ankara Yıldırım Beyazıt University |
|
Turkey |
2020-05-05 |
2020-06-18 |
2020, NCT04438954 |
Phase Not Applicable |
Completed |
1 |
1 Month |
30 |
|
2020-06-23 |
| Psychological Preparedness towards Novel Coronavirus Precautionary Measures – an online survey |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Chinese University of Hong Kong |
|
China |
2020-06-16 |
2021-06-15 |
ChiCTR2000033936 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
1000 |
Allen Ting Chun LEE, Linda Chiu Wa LAM |
2020-06-23 |
| Virtual Assistant for COVID-19 PPE |
Coronavirus disease 19 infection |
Amazon Alexa alone, Human Coach alone, Virtual Assistant alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The University Health Network |
|
|
2020-06-30 |
2021-05-01 |
20-5399, NCT04435275 |
Phase Not Applicable |
Not yet recruiting |
0 |
10 Months |
50 |
Rongyu ( Cindy) Jin |
2020-06-24 |
| A medical records based study for the influence of novel coronavirus pneumonia (COVID-19) on the symptoms of patients with achalasia |
Achalasia, Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
General Hospital of Tianjin Medical University |
National Natural Science Foundation of China |
China |
2020-06-16 |
2020-06-23 |
ChiCTR2000033919 |
Phase Not Applicable |
Recruiting |
1 |
|
|
LingYun Zhang, Wei Zhao |
2020-06-23 |
| CP IN COVID19: Use of Convalescent Plasma for Treatment of Patients With COVID-19 Infection |
Coronavirus disease 19 infection, Respiratory failure |
convalescent plasma alone, standard of care alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Cairo University |
|
Egypt |
2020-06-01 |
2021-12-31 |
CP IN COVID19, N39-2020, NCT04438694 |
Phase 1/Phase 2 Clinical |
Recruiting |
1 |
19 Months |
60 |
Akram AbdelBarry, MD PhD, Ashraf ElFiky, MD PhD, Azza AboulEnin, MD PhD, Heba Sharaf, Md PhD, Mostafa ElShazly, MD PhD, Nermeen El Desouky, Nermeen ElDesouky, MD PhD, Omar Fahmy, MD PhD, Yasser Nassar, MD PhD |
2020-06-23 |
| OBVIONCO: Prospective, Cohort Study to Describe the Clinical Characteristics of COVID-19, the Acquired Immune Response and the Biological and Clinical Parameters of Patients Followed in Oncology by the Saint-Joseph Hospital Group for a Period of 6 Months During the COVID-19 Pandemic |
Coronavirus disease 19 infection |
Obvio-19 mobile app alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Groupe Hospitalier Paris Saint-Joseph |
ObvioHealth |
France |
2020-06-30 |
2021-12-31 |
NCT04437719, OBVIONCO, OBVIONCO |
Phase Not Applicable |
Not yet recruiting |
1 |
18 Months |
100 |
Eric Raymond, MD, Helene Beaussier, PharmD, pHD |
2020-06-23 |
| IMMUNOVID: Evaluation of Immune Response in COVID-19 Patients |
Coronavirus disease 19 infection |
antibiotic prophylaxis alone, anticoagulant treatment alone, hydroxychloroquine alone, lopinavir + ritonavir alone, off-label therapy alone, hydroxychloroquine plus lopinavir + ritonavir |
HIV protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Azienda Ospedaliera Universitaria Integrata Di Verona |
|
Italy |
2020-03-26 |
2020-11-26 |
IMMUNOVID, IMMUNOVID 2590CESC, NCT04438629 |
Phase Not Applicable |
Recruiting |
2 |
8 Months |
80 |
STEFANO UGEL, VINCENZO BRONTE, MD |
2020-06-23 |
| Hydroxychloroquine Post-Exposure Prophylaxis for Coronavirus Disease (COVID-19) Among Health-Care Workers |
Coronavirus disease 19 infection |
hydroxychloroquine alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Rambam Health Care Campus |
|
Israel |
2020-06-30 |
2022-06-30 |
0193-20-RMB CTIL, NCT04438837 |
Phase 2 Clinical |
Not yet recruiting |
1 |
24 Months |
582 |
Mical Paul, MD, Nesrin Ghanem-Zoubi, Nesrin Ghanem-Zoubi MD, Nesrin Ghanem-Zoubi, MD |
2020-06-25 |
| COVID-PRONE: Contribution of a Prone Team in Intensive Care During the Covid-19 Epidemic |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hopitaux Universitaires de Strasbourg |
|
France |
2020-03-25 |
2020-06-20 |
7911, COVID-PRONE, NCT04438941 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
100 |
Anne-Florence ROUBY, MD, Bob HEGER, MD, Nabil CHAKFE, MD, PhD, Olivier COLLANGE, MD, PhD, Paul-Michel MERTES, MD, PhD, Saïd CHAYER, PhD, HDR |
2020-06-24 |
| Daily Home Spirometry for Early Detection of Pulmonary Complications in Patients With COVID19 |
Coronavirus disease 19 infection, Respiratory disease |
Portable hand-held spirometer alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sheba Medical Center |
|
Israel |
2020-09-01 |
2021-09-01 |
NCT04438863, SHEBA-20-7022-SMC-LL-CTIL |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
90 |
Dr. Liran Levy, Transplant pulmonologist |
2020-06-23 |
| COVICARE: The COVID-19 Disease and Cardiac Events Study |
Coronavirus disease 19 infection, Heart injury |
echocardiography alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
NHS Lanarkshire |
|
UK |
2020-05-29 |
2020-11-30 |
COVI-RW-2020, COVICARE, NCT04438993 |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
100 |
Robin A Weir, MD, Robin AP Weir, MD |
2020-06-23 |
| To study effect of Ivermectin drug in patients infected with SARS-CoV-2 virus |
Coronavirus disease 19 infection |
ivermectin alone |
Chloride channel modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Symbiosis International University |
|
India |
2020-06-18 |
|
CTRI/2020/06/025960 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
100 |
Dr Meenakshi Bhakare, Dr Rajkumar Nikalje, Dr Vijay Natarajan |
2020-06-23 |
| A clinical trial of BD-368-2 for SARS-CoV-2 infection |
Coronavirus disease 19 infection |
BD-368-2 alone |
COVID19 Spike glycoprotein modulator |
|
Peking University |
Beijing Advanced Medical Technologies Inc |
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-06-23 |
| Clinical Study to Study Safety and Efficacy of herbal formulation - Aayudh Advance |
Coronavirus disease 19 infection |
Aayudh Advance alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shukla Ashar Impex Pvt. Ltd., Rajkot |
|
India |
2020-06-22 |
|
ARL/CSP/2020/003-00, CTRI/2020/06/025977 |
Phase 2 Clinical |
Recruiting |
1 |
|
120 |
Dr Bhavdeep Ganatra, Dr Manish Rachchh, Dr Parul Bhatt |
2020-06-23 |
| Ibrutinib for the Treatment of COVID-19 in Patients Requiring Hospitalization |
Aplastic anemia, Coronavirus disease 19 infection, Hematological neoplasm, Lymphocytosis, Myelodysplastic syndrome, Paraproteinemia, Solid tumor |
ibrutinib alone |
Btk tyrosine kinase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ohio State University Comprehensive Cancer Center |
National Cancer Institute |
US |
2020-06-15 |
2022-12-31 |
NCI-2020-03341, NCT04439006, OSU-20135, P30CA016058 |
Phase 2 Clinical |
Not yet recruiting |
1 |
30 Months |
72 |
Jennifer A Woyach, MD, Jennifer A. Woyach, MD, Kaitlyn Dvorak, Ohio State Comprehensive Cancer Center |
2020-06-23 |
| A Clinical study of CWP-291 in treatment of COVID-19 |
Coronavirus disease 19 infection |
CWP-291 alone |
Beta-catenin inhibitor |
|
JW Pharmaceutical Corp |
|
South Korea, US |
|
|
|
Phase Not Applicable |
Completed |
2 |
|
|
|
2020-06-22 |
| Study of the Efficacy and Safety of STI-5656 (Abivertinib Maleate) With SOC Versus SOC in Subjects With COVID-19 (SOC) |
Coronavirus disease 19 infection, Viral pneumonia |
STI-5656 alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sorrento Therapeutics Inc |
|
|
2020-08-31 |
2021-03-31 |
NCT04440007, STI-5656-2001 |
Phase 2 Clinical |
Not yet recruiting |
0 |
7 Months |
80 |
Mike Royal, MD, Ying Yan, MD MS |
2020-06-23 |
| An international, randomized, controlled trial to evaluate non-licensed COVID-19 treatments in addition to standard of care among hospitalized patients |
Coronavirus disease 19 infection |
hydroxychloroquine alone, lopinavir + ritonavir alone, remdesivir alone, standard care alone, interferon beta-1a plus lopinavir + ritonavir |
COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, HIV protease inhibitor, RNA polymerase modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universidad Peruana Cayetano Heredia |
Ministry Of Health, Lima Peru |
Norway, India, Peru, Thailand, Argentina, Switzerland, Iran, South Africa, Bahrain, Spain |
2020-04-03 |
|
PER-010-20 |
Phase 4 Clinical |
Recruiting |
20 |
|
50000 |
ALEJANDRO PEÑA VILLALOBOS, ALONSO RICARDO SOTO TARAZONA, Alejandro DALY TURCKE, Anabel Viton Espino, Andres Martín Alcantara Díaz, Anna Larson Williams, CLAUDIA LIZETTE BANDA FLORES, Carla Cornejo Valdivia, Carlos Velapatiño Flores, EDISON DANTE MEREGILDO RODRIGUEZ, EPIFANIO SANCHEZ GARAVITO, FRANCO LEON JIMENEZ, Fernando Mejia Cordero, GERMAN JAVIER MALAGA RODRÌGUEZ, GONZALO GIANELLA MALCA, Guillermo Carlos Contreras Nogales, HUGO ARBAÑIL HUAMAN, Hernán Sandoval Manrique, JESUS CHACALTANA HUARCAYA, JORGE MANUEL DE LOS RÍOS SENMACHE, JORGE WATANBE NOJI, Jenny Perez Cervantes, Jesus Canales Vargas, Jesus Juarez Eyzaguirre, Jesus Valverde Huaman, Jose Eduardo Gotuzzo Herencia, Juan Pablo Majluf Brahim, Julio Antonio Silva Ramos, Julio Bolaños Vargas, Kory Marcela Argumedo Estay, Kory Rojas Murrugarra, LUIS ENRIQUE HERCILLA VASQUEZ, LUIS RICARDO ILLESCAS MUCHA, Luis Castillo sin, MARIA ANGELICA PAREDES MORENO, MARIO PATRICIO CORNEJO GIRALDO, MARTIN MONTES DELGADO, MARTIN OYANGUREN MIRANDA, MIGUEL HUEDA ZAVALETA, Manuel Eduardo Giron Silva, Martin Montes Delgado, Miguel Villegas Chiroque q, Oscar Martín Torres Ruiz, Patricia García Funegra, Paula Ponce de León Lovatón, Pedro Alberto Sullon Zavaleta, Raul Junior Gonzalez Navarro, Ricardo Manuel Sanchez Sevillano, Rocío Jiménez Rodriguez, Rosa Lopez Martinez, Walter Hidalgo Caceres |
2020-06-23 |
| An Open Study of the Safety, Tolerability and Immunogenicity of 'Gam-COVID-Vac Lyo' Vaccine Against COVID-19 |
Coronavirus disease 19 infection |
Gam-COVID-Vac alone |
COVID19 Spike glycoprotein modulator |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Gamalei Institute of Epidemiology and Microbiology |
Accellena Research and Development |
Russian Federation |
2020-06-17 |
2020-08-15 |
03-GAM-COVID-VAC LYO-2020, NCT04437875 |
Phase 1/Phase 2 Clinical |
Recruiting |
1 |
1 Month |
38 |
Inna Dolzhikova, PhD, Lola Morozova, Md |
2020-06-25 |
| A randomised, double-blind, placebo-controlled trial of SFX-01 for the treatment of COVID-19 infection |
Coronavirus disease 19 infection |
alpha-cyclodextrin-stabilized sulforaphane (cancer/multiple sclerosis/subarachnoid hemorrhage/autism/glioblastoma/Non alcoholic steatohepatitis/Non alcoholic fatty liver disease), Evgen Pharma alone |
Kelch like ECH associated protein 1 modulator, Nuclear erythroid 2-related factor 2 stimulator |
|
Evgen Pharma plc, University of Dundee |
LifeArc |
UK |
|
|
|
Phase Not Applicable |
Planned |
1 |
|
|
|
2020-06-22 |
| HCQ-COVID19: Post-Exposure Prophylaxis in Healthcare Workers Exposed to COVID-19 Patients |
Coronavirus disease 19 infection |
hydroxychloroquine alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hamad Medical Corp |
|
Qatar |
2020-07-01 |
2021-12-31 |
HCQ-COVID19, MRC-02-20-442, NCT04437693 |
Phase 3 Clinical |
Not yet recruiting |
1 |
18 Months |
500 |
Nasser Al Ansari, FRCPath, Rajvir Singh, Ph.D. |
2020-06-25 |
| A clinical trial of anti-SARS-CoV2 antibodies (COVID-19 infection), Yumab for the potential treatment of COVID-19 infection |
Coronavirus disease 19 infection |
anti-SARS-CoV2 antibodies (COVID-19 infection), Corat Therapeutics alone |
|
|
Corat Therapeutics GmbH, Yumab |
|
|
2020-12-31 |
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-06-19 |
| SEARCH: A large-scale study to better understand the spread and prevalence of the coronavirus in the local community, with an initial focus on evaluating healthcare workers and first responders |
Coronavirus disease 19 infection |
|
|
|
Rady Children's Hospital, San Diego, Scripps Research Institute, University of California San Diego |
|
US |
|
|
SEARCH |
Phase Not Applicable |
Status not specified |
1 |
|
10000 |
Gene Yeo, Kristian Andersen, Lauge Farnaes, Louise Laurent, Rob Knight |
2020-06-22 |
| The Health Crisis at the Healthcare Professionals, Careers and Non-careers, a Month After the Containment Period |
Anxiety disorder, Coronavirus disease 19 infection, Depression |
|
|
|
Clinique Medipole Garonne |
|
|
2020-06-15 |
2020-06-28 |
DECOVID, NCT04436861 |
Phase Not Applicable |
Not yet recruiting |
0 |
|
200 |
Laurence Culine, Myaro Nodjialem |
2020-06-22 |
| A clinical trial of REGN-CoV2 for the treatment of COVID-19 patients (both those who are hospitalized and those who are not) |
Coronavirus disease 19 infection |
REGN-CoV2 alone |
|
|
Regeneron Pharmaceuticals Inc, University of Maryland Medical Center |
|
|
|
|
|
Phase Not Applicable |
Recruiting |
0 |
|
|
|
2020-06-19 |
| REACT: Rehabilitation Needs After COVID-19 Hospital Treatment |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Azienda Unita Sanitaria Locale di Reggio Emilia |
|
Italy |
2020-06-30 |
2020-12-31 |
428/2020/OSS/AUSLRE, NCT04438239, REACT |
Phase Not Applicable |
Not yet recruiting |
1 |
6 Months |
100 |
Stefania Costi, PhD, Stefania Fugazzaro, MD |
2020-06-23 |
| Open-label, placebo-controlled, multicenter, clinical trial to assess the effect and safety of Favipiravir compared to standard care in the management of adult patients with moderate Covid-19 at risk of serious complications |
Coronavirus disease 19 infection |
favipiravir alone |
RNA polymerase inhibitor |
|
Hospital Regional de Alta Especialidad de Ixtapaluca |
|
Mexico |
|
|
C32-20 |
Phase 3 Clinical |
Status not specified |
1 |
|
200 |
|
2020-06-22 |
| Efficacy of Intravenous Infusions of Stem Cells in the Treatment of COVID-19 Patients |
Coronavirus disease 19 infection, Lung inflammation |
standard of care alone, Variable regimens including umbilical cord-derived mesenchymal stem cells |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Jinnah Hospital |
Johns Hopkins University |
Pakistan |
2020-06-01 |
2021-06-30 |
JB and RSC-01, NCT04437823 |
Phase 2 Clinical |
Recruiting |
1 |
13 Months |
20 |
Azra Mehmood, PhD, Moazzam N Tarar, MBBS, FCPS, Mohsin Shahzad, PhD, Prof. Sheikh Riazuddin, Sheikh Riazuddin, PhD |
2020-06-23 |
| Niclosamide In Moderate COVID-19 |
Coronavirus disease 19 infection, Gastrointestinal disease, Viral pneumonia |
Standard of care therapy alone, niclosamide alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
First Wave Bio, Inc |
|
|
2020-08-31 |
2021-02-28 |
FW-COV-002, NCT04436458 |
Phase 2 Clinical |
Not yet recruiting |
0 |
6 Months |
100 |
Tony Opipari, M.D. |
2020-06-22 |
| IBOC: Immune Biomarkers of Outcome From COVID-19 |
Coronavirus disease 19 infection, Immune disorder |
Peripheral blood sampling alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Plymouth NHS Trust |
|
UK |
2020-04-29 |
2020-10-28 |
20/HEP/381, IBOC, NCT04436484 |
Phase Not Applicable |
Recruiting |
2 |
6 Months |
200 |
Ashwin D Dhanda, MRCP PhD, Christopher Rollinson |
2020-06-23 |
| Adalimumab effect on COVID-19 |
Coronavirus disease 19 infection |
adalimumab alone |
TNF alpha ligand inhibitor, TNF binding agent |
|
Bagheiat-allah University of Medical Sciences |
|
Iran |
2020-04-29 |
|
IR.BMSU.REC.1399.062, IRCT20171105037262N4 |
Phase 3 Clinical |
Recruiting |
1 |
|
100 |
Hassan Nikoueinejad, Hassan Nikoueinejas, Mohammad Hossein Pourhanifeh |
2020-06-22 |
| Treatment of COVID-19 with the inhalation drug pulmozyme |
Coronavirus disease 19 infection, Respiratory disease |
dornase alfa alone |
Deoxyribonuclease I stimulator, Deoxyribonuclease stimulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Region Skane |
|
Sweden |
2020-05-18 |
|
2020-001849-39, NETs-C19 |
Phase 2 Clinical |
Recruiting |
1 |
|
|
Adam Linder |
2020-06-22 |
| Evaluating the Efficacy of Convalescent Plasma in Symptomatic Outpatients Infected With COVID-19 |
Coronavirus disease 19 infection |
convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Metro Infectious Disease Consultants |
|
US |
2020-07-06 |
2021-07-06 |
MIDC-CCP, NCT04438057 |
Phase 2 Clinical |
Not yet recruiting |
1 |
12 Months |
150 |
Nathan Skorodin, PharmD, Nicholas Van Hise, PharmD |
2020-06-23 |
| Study evaluating the impact of BCG vaccination on the incidence and course of SARS-CoV-2 infection among health care workers in Poland during the COVID-19 pandemic |
Coronavirus disease 19 infection |
BCG vaccine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Rzeszów |
Medical Research Agency (Agencja Badań Medycznych) |
Poland |
2020-06-26 |
|
2020-002111-22, BCG/COVID-19/UR/04/2020 |
Phase 3 Clinical |
Recruiting |
1 |
|
|
National Study Coordinator |
2020-06-23 |
| A study to assess human monoclonal antibodies (Covid-19) in the treatment of patients infected with SARS-CoV-2 |
Coronavirus disease 19 infection |
human monoclonal antibodies (Covid-19), Garvan Institute/The Kirby Institute alone |
COVID19 Spike glycoprotein modulator |
|
The Kirby Institute (Affiliated With The University Of New South Wales) |
|
Australia |
|
|
|
Phase Not Applicable |
Planned |
1 |
|
|
Professor Daniel Christ |
2020-06-19 |
| Edaravone in COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia |
edaravone, Zist Daru Co alone, standard treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tabriz University of Medical Sciences |
|
Iran |
2020-06-21 |
|
IR.TBZMED.REC.1399.128, IRCT20200317046797N6 |
Phase 3 Clinical |
Recruiting |
1 |
|
30 |
Dr Mohammad Samiei, Mohammadreza Ardalan, Mojtaba Varshochi, Sepideh Zununi Vahed |
2020-06-22 |
| Evaluation of Vaginal Fluid for Covid-19 Positivity in Women With Positive nasopharyngeal Covid-19 Test |
Coronavirus disease 19 infection |
vginal fluid Covid-19 PCR test alone |
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Acibadem University |
|
Turkey |
2020-06-15 |
2020-07-30 |
ACIBADEM MASLAK OB&GYN, NCT04437940 |
Phase Not Applicable |
Recruiting |
1 |
1 Month |
35 |
Burak Celik, Eren Kaya, MD, Ozguc Takmaz, Ozguc Takmaz, Assist. Prof., Ozguc Takmaz, MD,Assist.Prof |
2020-06-22 |
| Snowball: Network-Targeted Strategies for Efficient Community SARS-CoV-2 (COVID-19) Sampling |
Coronavirus disease 19 infection |
COVID-19 testing alone, network targeted sampling alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Duke University |
|
US |
2020-07-01 |
2021-06-30 |
NCT04437706, PRO00105430, Snowball |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
200 |
Erich Huang, MD, PhD, Margaret K Pendzich, MSPH, Margaret Pendzich, Pedro Gomez, MS |
2020-06-23 |
| COVID Screening Strategies in Homeless Shelters |
Coronavirus disease 19 infection |
daily active screening alone, self-collected nasal swabbing alone, self-collected nasopharyngeal swabbing alone, self-collected oral swabbing alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
St Josephs Healthcare Hamilton |
|
Canada |
2020-04-10 |
2020-06-30 |
2020-10864-T, NCT04438070 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
400 |
Marek Smieja, Marek Smieja, MD, PhD, Timothy O'Shea, MD |
2020-06-23 |
| A phase I study of PDS-0204 for the prevention of COVID-19 infection |
Coronavirus disease 19 infection |
PDS-0204 alone |
|
|
Farmacore Biotecnologia Limitada, PDS Biotechnology Corp |
Ministry of Science and Technology, Brazil |
Brazil |
|
|
|
Phase 1 Clinical |
Planned |
1 |
|
|
|
2020-06-19 |
| A Clinical study of prophylactic vaccine (Memopi, COVID-19), OSE Immunotherapeutics in COVID-19 |
Coronavirus disease 19 infection |
prophylactic vaccine (Memopi, COVID-19), OSE Immunotherapeutics alone |
|
|
OSE Immunotherapeutics |
|
|
2020-12-31 |
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-06-19 |
| A Study of Ad26-COVS1 in Adults (COVID-19) |
Coronavirus disease 19 infection |
JNJ-78436735 alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Janssen Vaccines & Prevention BV |
|
US, Belgium |
2020-07-13 |
2023-07-08 |
2020-001483-28, CR108828, NCT04436276, VAC31518COV1001 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
12 |
35 Months |
1045 |
Janssen Vaccines & Prevention B.V. Clinical Trial, Study Contact |
2020-06-23 |
| Double-blind, placebo-controlled clinical trial of the use of colchicine for the management of patients with mild and severe SARS-Cov2 infection |
Coronavirus disease 19 infection |
colchicine alone |
|
|
Instituto Nacional de Ciencias Medicas y Nutricion |
|
Mexico |
|
|
3374 |
Phase 2 Clinical |
Status not specified |
1 |
|
|
|
2020-06-19 |
| NICCAM: A study to investigate the safety and efficacy of two approved drugs, niclosamide and camostat, administered alone and in combination and compared to placebo in COVID-19 patients |
Coronavirus disease 19 infection |
Niclosamide plus camostat mesylate |
Serine protease inhibitor, Transmembrane serine protease 2 inhibitor, Trypsin inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Charite Research Organisation |
Bayer AG |
Germany |
2020-06-17 |
|
2020-002233-15, NICCAM, NICCAM-001 |
Phase 2 Clinical |
Recruiting |
1 |
|
72 |
Kristin Herzog |
2020-06-22 |
| Effect of Interferential Therapy on SARS-CoV-2. COVID-19 |
Coronavirus disease 19 infection |
SABA alone |
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Lagos State University Teaching Hospital |
|
Nigeria |
2020-10-01 |
|
PACTR202006717277937 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
48 |
Bashir Kaka, Eniola Awolola, Sonill Maharaj |
2020-06-22 |
| An Open Study of the Safety, Tolerability and Immunogenicity of the Drug 'Gam-COVID-Vac' Vaccine Against COVID-19 |
Coronavirus disease 19 infection |
Gam-COVID-Vac alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Gamalei Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation Collaborator |
Accellena Research and Development |
Russian Federation |
2020-06-17 |
2020-08-15 |
02-GAM-COVID-VAC-2020, NCT04436471 |
Phase 1/Phase 2 Clinical |
Recruiting |
1 |
1 Month |
38 |
Inna Dolzhikova, PhD, Irina Gagarina, MD |
2020-06-25 |
| Study of vascular complications in critically ill patients with coronavirus |
Coronavirus disease 19 infection, Vascular disease |
analgesics alone, antibiotics alone, heparin alone |
|
|
Universidade Federal de Sao Paulo - UNIFESP |
|
Brazil |
2020-04-17 |
|
3.976.579, 30667020.5.0000.5505, RBR-4qjzh7, U1111-1252-1318 |
Phase Not Applicable |
No longer recruiting |
1 |
|
|
Luis CU Nakano, Ronald LG Flumignan |
2020-06-22 |
| COVIDAR: Arrhythmias in COVID-19 |
Coronavirus disease 19 infection, Heart arrhythmia |
SARS-CoV2 infection treatment alone, routine clinical care alone |
|
|
Hospital Clinic of Barcelona |
Academic Medical Center, University of Amsterdam, Antwerp University Hospital, European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart, European Society of Cardiology, Istituto Auxologico Italiano, St George's University Hospitals NHS Foundation Trust |
UK, Netherlands, Belgium, Spain, Italy |
2020-06-30 |
2021-12-31 |
COVIDAR, HCB/2020/0333, NCT04437901 |
Phase Not Applicable |
Not yet recruiting |
5 |
18 Months |
10000 |
Alex Soriano, MD, PhD, Arthur A Wilde, MD, PhD, Elena Arbelo, MD, PhD, Elena Arbelo, MD, PhD, MSc, Elijah Behr, MD, PhD, Hein Heidbuchel, MD, PhD, Lia Crotti, MD, PhD, Marta Hernandez-Meneses, MD, Nynke Hoffman, MD, PhD |
2020-06-22 |
| Treatment of severe cases of Covid-19 with eculizumab |
Coronavirus disease 19 infection |
eculizumab alone |
Complement C5 factor inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital das Clinicas de Ribeirao Preto/USP |
|
Brazil |
2020-05-27 |
|
30522020.0.0000.5440, 4.003.844, A10741034670, RBR-876qb5 |
Phase 1/Phase 2 Clinical |
Recruiting |
1 |
|
10 |
Bruno Garcia Pires, Rodrigo Tocantins Calado |
2020-06-22 |
| A medical records based study for the preliminary efficacy of Tocilizumab in the treatment of the patients with novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
tocilizumab alone |
|
Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Wuhan Huoshenshan Hospital, Xijing Hospital |
Shaanxi Provincial Science and Technology Department |
China |
2020-02-27 |
2020-03-14 |
ChiCTR2000033705 |
Phase 4 Clinical |
No longer recruiting |
1 |
|
61 |
Xijing Zhang |
2020-06-22 |
| COV-EAT: Dietary and Lifestyle Habits During the Pandemic of COVID-19 in Greece |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
University of Thessaly |
|
Greece |
2020-04-30 |
2020-05-24 |
COV-EAT, COV-EAT, NCT04437121 |
Phase Not Applicable |
Completed |
1 |
|
397 |
Odysseas Androutsos, M.Med.Sci., Ph.D. |
2020-06-22 |
| A phase I study to assess the effect of human FGF-1 (long-term subcutaneous formulation, Parkinson's disease), Zhittya Genesis Medicine in patients with lung damage from COVID-19 |
Coronavirus disease 19 infection, Lung injury |
human fibroblast growth factor-1 (long-term subcutaneous formulation, Parkinson's disease/amyotrophic lateral sclerosis), Zhittya Genesis Medicine alone |
FGF-1 ligand |
|
Zhittya Genesis Medicine Inc |
|
|
|
|
|
Phase 1 Clinical |
Planned |
0 |
|
|
|
2020-06-19 |
| A case study on COVID-19 infection and treatment with hydroxychloroquine cause severe hemolysis crisis in a patient with glucose 6 phosphate dehydrogenase deficiency |
Coronavirus disease 19 infection, Enzyme deficiency |
hydroxychloroquine alone |
|
|
Geneva University Hospitals |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
1 |
|
2020-06-19 |
| A phase I study to assess the effect of human FGF-1 (long-term subcutaneous formulation, Parkinson's disease), Zhittya Genesis Medicine in patients with COVID-19 lung damage |
Coronavirus disease 19 infection, Lung injury |
human fibroblast growth factor-1 (long-term subcutaneous formulation, Parkinson's disease/amyotrophic lateral sclerosis), Zhittya Genesis Medicine alone |
FGF-1 ligand |
|
Zhittya Genesis Medicine Inc |
|
Mexico |
|
|
|
Phase 1 Clinical |
Planned |
1 |
|
|
|
2020-06-19 |
| Postpartum Depression in the Covid-19 Pandemic and the Impact of Anesthesia |
Anxiety disorder, Coronavirus disease 19 infection, Postnatal depression |
38 questions questionnaire alone, EPDS (Edinburgh Postnatal Depression Scale) alone, GAD-7 (General Anxiety Disorder) scale alone, PHQ-9 (Patient Health Questionnaire) Depression Scale alone |
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
General and Maternity Hospital of Athens Elena Venizelou |
Alexandra Hospital, Larissa University Hospital, National and Kapodistrian University of Athens, University of Ioannina |
Greece |
2020-06-30 |
2020-09-30 |
COVID-19 POSTPARTUM DEPRESSION, NCT04437342 |
Phase Not Applicable |
Not yet recruiting |
6 |
3 Months |
300 |
Chrysoula Staikou, Associate Professor, Dimitrios Valsamidis, Head of Department, Eleni Arnaoutoglou, Eleni Arnaoutoglou, Professor, Georgia Micha, PhD, Konstantinos Kotsis, Konstantinos Kotsis, Assistant Professor, Petros Tzimas, Petros Tzimas, Associate Professor |
2020-06-22 |
| The mechanism of PECAM-1 in mediating pulmonary vascular endothelial permeability through Wnt/beta-catenin signaling pathway in SARS-CoV-2-related ARDS |
Adult respiratory distress syndrome, Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The First Affiliated Hospital of Guangzhou Medical College |
|
China |
2020-07-01 |
2020-08-31 |
ChiCTR2000033699 |
Phase Not Applicable |
Not yet recruiting |
1 |
2 Months |
20 |
Xiaoqing Liu, Zhihui Zhang |
2020-06-22 |
| An investigator-initiated, Phase IIa, randomized, double-blind, placebo-controlled trial to assess safety and efficacy of ATI-450 in hospitalized patients with COVID-19 |
Coronavirus disease 19 infection |
ATI-450 alone |
Adapter molecule crk inhibitor, MAPKAPK2 inhibitor |
|
University of Kansas Medical Center |
Aclaris Therapeutics Inc |
US |
|
|
|
Phase 2a Clinical |
Not yet recruiting |
1 |
|
36 |
Deepika Polineni, M.D., M.P.H, Gregory Gan, M.D., Ph.D |
2020-06-19 |
| A open-label study to target the inflammatory cascade with anakinra in moderate to severe COVID-19 pneumonia- case-series |
Coronavirus disease 19 infection, Pneumonia |
anakinra alone |
Type I IL-1 receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Caen University Hospital |
|
|
|
|
|
Phase 2 Clinical |
Status not specified |
0 |
|
9 |
|
2020-06-19 |
| A clinical validation study to evaluate VaxArray Coronavirus SeroAssay for the diagnosis of COVID-19 |
Coronavirus disease 19 infection |
VaxArray coronavirus seroassay alone |
|
|
InDevR LLC |
Children's Hospital Colorado |
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
100 |
|
2020-06-19 |
| Effectiveness of borage based solutions in cytokine's levels in covid-19 ARDS patients |
Adult respiratory distress syndrome, Coronavirus disease 19 infection, Respiratory failure |
Borage suspension therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shahid Beheshti University of Medical Sciences, Laser Application in Medical Sciences Research Center |
|
Iran |
2020-03-20 |
|
IR.SBMU.NRITLD.REC.1399.059, IRCT20150107020592N28 |
Phase 3 Clinical |
No longer recruiting |
1 |
|
50 |
Afshin Zarghi, Seyed Mohammad Reza Hashemian, Seyyed Mohammadreza Hashemian |
2020-06-24 |
| To describe the case of a critically-ill patient with myocarditis and severe ARDS related to COVID-19 infection: A case-study |
Coronavirus disease 19 infection, Myocarditis, Respiratory distress syndrome |
AT-001 alone, fraction of inspired oxygen alone, milrinone alone, neuromuscular blockade alone, positive end-expiratory pressure alone, tocilizumab alone, Variable regimens including colchicine , methylprednisolone , prednisone |
PDE 3 inhibitor |
Male |
Advocate Illinois Masonic Medical Center |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
1 |
|
2020-06-22 |
| USCovid: Reliability of a Pocket Sized Ultrasound Scanner in the Evaluation Covid-19 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
LUS (lung ultrasound scan) alone, pocket-sized ultrasound scanner (Butterfly Network Inc., Butterfly iQ) alone, ultrasound scanner (GE Healthcare, Venue GO) alone |
|
|
University of Siena |
|
Italy |
2020-03-15 |
2020-06-10 |
NCT04433000, USCOVID, USCovid |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
34 |
David Bennett, MD, Piersante Sestini, MD, Sestini Piersante, MD |
2020-06-22 |
| A case-series study to follow the clinical course of COVID-19 in patients with systemic lupus erythematosus (SLE) who received long-term treatment with hydroxychloroquine: a case-series |
Coronavirus disease 19 infection |
hydroxychloroquine alone, invasive mechanical ventilation alone, oxygen therapy alone, prednisone alone |
|
|
Sorbonne Universites |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
17 |
|
2020-06-19 |
| POCUS COVID-19: Evaluation with ultrasound on the bedside in serious patients with COVID-19 |
Coronavirus disease 19 infection |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universidade Federal de Sao Paulo - UNIFESP |
|
Brazil |
2020-04-21 |
2020-07-21 |
3.982.657, 30815320.5.0000.5505, POCUS COVID-19, RBR-43hbks, U1111-1252-1143 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
50 |
Luis CU Nakano, Ronald LG Flumignan |
2020-06-22 |
| Effect of convalescent plasma in patients with severe COVI-19 |
Coronavirus disease 19 infection |
convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Instituto Estadual de Hematologia Arthur de Siqueira Cavalcanti, Instituto do Cerebro de Brasilia |
|
Brazil |
2020-04-19 |
2020-05-31 |
3,980,508, 30487220.8.1001.5267 - CAAE, RBR-4vm3yy, U1111-1251-9286 |
Phase 2 Clinical |
Recruiting |
1 |
1 Month |
20 |
Pedro Kurtz |
2020-06-22 |
| A First-in-Human Study in Adult Subjects Hospitalized with COVID-19 to Investigate a new product called ARGX-117 |
Coronavirus disease 19 infection |
ARGX-117 alone |
Complement factor C2 modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
argenx BV, Belgium |
|
Belgium |
2020-04-21 |
|
2020-001546-19, ARGX-117-2001 |
Phase 1/Phase 2 Clinical |
Recruiting |
1 |
|
|
Regulatory |
2020-06-22 |
| The role of early dialysis in the evolution of patients with COVID-19 |
Coronavirus disease 19 infection, Renal injury |
hemodialysis alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Unidade de Pesquisa Clínica - Hospital das Clínicas da Faculdade de Medicina de Botucatu |
Fundacao de Amparo a Pesquisa do Estado Sao Paulo |
Brazil |
2020-05-01 |
|
30614920.5.0000.5411, 4.004.277, RBR-3rdhgm, U1111-1251-0203 |
Phase Not Applicable |
Recruiting |
1 |
|
118 |
Welder Zamoner |
2020-06-22 |
| Treatment of 2019-nCoV pneumonia with N-acetylcysteine |
Coronavirus disease 19 infection, SARS coronavirus infection, Viral pneumonia |
N-acetylcysteine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Sao Paulo |
Fundacao de Amparo a Pesquisa do Estado Sao Paulo |
Brazil |
2020-04-14 |
|
3,947,348, 30420720.4.0000.0068, RBR-8969zg, U1111-1250-3564 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
140 |
Julio Cesar Garcia de Alencar |
2020-06-22 |
| SequelaeCov: Lung Damage Caused by SARS-CoV-2 Pneumonia (COVID-19) |
Coronavirus disease 19 infection, Lung injury, Respiratory failure, Viral pneumonia |
continuous positive airway pressure therapy alone, invasive mechanical ventilation alone, non-invasive ventilation alone, oxygen support therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Milano-Bicocca |
|
Italy |
2020-08-17 |
2021-04-30 |
NCT04435327, SEQUELAECOV, SequelaeCov |
Phase Not Applicable |
Recruiting |
1 |
8 Months |
300 |
Paola Faverio, MD |
2020-06-22 |
| VANGARD: PB-1046, a Long-acting, Sustained Release Human VIP Analog, Intended to Provide Clinical Improvement to Hospitalized COVID-19 Patients at High Risk for Rapid Clinical Deterioration and Acute Respiratory Distress Syndrome (ARDS) |
Coronavirus disease 19 infection, Respiratory distress syndrome |
PB-1046 alone |
VIP 2 receptor agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
PhaseBio Pharmaceuticals Inc |
|
US |
2020-06-26 |
2020-12-18 |
NCT04433546, PB1046-PT-CL-0007, VANGARD |
Phase 2 Clinical |
Not yet recruiting |
1 |
5 Months |
210 |
Clinical Trials |
2020-06-23 |
| A Comparative Study on Ivermectin and Hydroxychloroquine on the COVID19 Patients in Bangladesh |
Coronavirus disease 19 infection |
Variable regimens including azithromycin , doxycycline hyclate , hydroxychloroquine , ivermectin |
Chloride channel modulator |
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ministry of Health and Family Welfare, Bangladesh |
Xi'an Jiaotong University |
Bangladesh |
2020-05-02 |
2020-06-05 |
10000918, NCT04434144 |
Phase Not Applicable |
Completed |
1 |
1 Month |
116 |
Abu Taiub Mohammed Mohiuddin Chowdhury, MBBS, MD, Mohammad Shahbaz, MBBS, MCPS |
2020-06-22 |
| Efficacy of Hydroxychloroquine Prophylaxis for Health Care Workers at High Risk for COVID-19 |
Coronavirus disease 19 infection |
hydroxychloroquine alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of New Mexico |
|
US |
2020-04-14 |
2025-04-14 |
20-206, NCT04435808 |
Phase 1/Phase 2 Clinical |
Recruiting |
1 |
60 Months |
350 |
Hadya Khawaja, MS, Walter Dehority, Walter Dehority, MD |
2020-06-22 |
| Effectiveness of herbal capsule in COVID-19 |
Coronavirus disease 19 infection |
herbal powder capsule (Punica granatum, Rheum palmatum, Glycyrrhiza glabra and Nigella sativa) alone, standard COVID-19 treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Kerman University of Medical Sciences |
|
Iran |
2020-04-20 |
|
IR.KMU.REC.1399.055, IRCT20200330046899N1 |
Phase 3 Clinical |
Recruiting |
1 |
|
50 |
Abbas Pardakhti, Dr. Hamid Aboosaeidi, Dr. Mohammad Setayesh, Mohammad Seatyesh, Mohammad Setayesh |
2020-06-22 |
| Study of the Efficacy and Safety of Intravenous Pamrevlumab, in Hospitalized Patients With Acute COVID-19 Disease |
Coronavirus disease 19 infection, Viral pneumonia |
pamrevlumab alone, standard-of-care alone |
Connective tissue growth factor ligand inhibitor |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
FibroGen Inc |
|
US |
2020-06-20 |
2021-01-31 |
FGCL-3019-098, NCT04432298 |
Phase 2 Clinical |
Recruiting |
1 |
7 Months |
130 |
Gustavo Lorente |
2020-06-25 |
| A Randomized Controlled Trial Assessing the Efficacy of Lianhua Qingwen as an Adjuvant Treatment in Patients With Mild Symptoms of COVID-19 |
Coronavirus disease 19 infection |
lianhua qingwen (oral/capsule, influenza), Yiling Pharmaceutical alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Nanyang Technological University |
Ministry of Health, Singapore |
Singapore |
2020-07-31 |
2021-02-28 |
IRB-2020-05-029, NCT04433013 |
Phase 3 Clinical |
Not yet recruiting |
1 |
7 Months |
300 |
Hui Zi Chua, Yan Zhao |
2020-06-22 |
| CRITICAL: Crizanlizumab for Treating COVID-19 Vasculopathy |
Coronavirus disease 19 infection, Inflammatory disease, Respiratory tract infection, Thrombosis, Vascular disease |
crizanlizumab alone |
P selectin antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Johns Hopkins University |
Brigham & Women's Hospital, Novartis AG, SOCAR Research SA |
US |
2020-06-30 |
2020-10-31 |
CRITICAL, IRB00249874, NCT04435184 |
Phase 2 Clinical |
Not yet recruiting |
1 |
4 Months |
40 |
Charles J Lowenstein, MD, Charles Lowenstein, MD, Shannon Kelley, BS, Thorsten Leucker, MD PhD |
2020-06-18 |
| A study of 254 nm UVC ray therapy in pharynx for asymptomatic to mild cases of coronavirus disease |
Coronavirus disease 19 infection |
standard of care alone, ultraviolet C therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Akshardeep Eye Hospital |
|
India |
2020-06-11 |
|
CTRI/2020/06/025766 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
300 |
Dr Jagdeep Kakadia |
2020-06-19 |
| Clinical observation of the relieving effect of Kegan Liyan oral liquid on the throat symptoms of novel coronavirus pneumonia (COVID-19) in convalescence, suspected patients and other susceptible people |
Coronavirus disease 19 infection |
Kegan Liyan alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Dongguan People's Hospital |
|
China |
2020-06-10 |
2020-12-31 |
ChiCTR2000033720 |
Phase 4 Clinical |
Not yet recruiting |
1 |
6 Months |
240 |
Chen Yiyun, Guan Ling, Hu Guanying |
2020-06-22 |
| SIDCOVID: A randomized, controlled clinical trial to determine the efficacy of siddha drugs in COVID-19 patients |
Coronavirus disease 19 infection |
Variable regimens including Amukkara choornam , Kabasura kudineer , Thalisathi choornam , adathodai manappagu |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Institute of Siddha |
|
India |
2020-06-15 |
|
CTRI/2020/06/025763, SIDCOVID |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
150 |
G J Christian, Meenakumari R |
2020-06-19 |
| Effectiveness of lying face down in improving the outcome of COVID-19 patients |
Coronavirus disease 19 infection |
Awake self proning strategy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
AIIMS Jodhpur |
|
India |
2020-06-20 |
|
CTRI/2020/06/025804 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
120 |
Dr Maya Gopalakrishnan |
2020-06-22 |
| LUSCOVIDPREG: Descriptive and Evaluation Study of the Use of Pulmonary Ultrasound in the Initial Management of Pregnant Women in the Context of COVID-19 |
Coronavirus disease 19 infection |
lung ultrasound alone |
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assistance Publique Hopitaux De Marseille |
|
France |
2020-06-15 |
2021-06-15 |
2020-30, 2020-A01303-36, LUSCOVIDPREG, NCT04432805 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
160 |
Jean-Olivier ARNAUD, Director, Julie BLANC, PH |
2020-06-22 |
| COPE: COPE - COVID-19 in Pregnancy and Early Childhood |
Coronavirus disease 19 infection |
biological samples, questionnaires and interviews alone |
|
Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sahlgrenska University Hospital |
|
Sweden |
2020-06-02 |
2041-06-02 |
2020-02848 0604, COPE, NCT04433364 |
Phase Not Applicable |
Recruiting |
26 |
252 Months |
1200 |
Anna Sandström, MD PhD, Anna-Carin Wihlbäck, MD PhD, Anna-Karin Wikström, MD PhD, Daniel Axelsson, MD, Elisabeth Salekärr, research nurse, Emelie Ottosson, MD, Hanna Östling, MD PhD, Helena Fadl, MD PhD, Hugo Hessel, MD, Inger Sundström, MD PhD, Johanna Molin, MD, Karin Pettersson, MD PhD, Linda Hjertberg, MD, Magnus Domellöf, MD PhD, Maria Jonsson, MD PhD, Maria Svenvik, MD, Marie Blomberg, MD PhD, Marie Vikström Bohlin, MD PhD, Marie-Charlotte A Nilsson, Midwife, Matilda Friman-Mathiasson, MD, Mehreen Zaigham, MD PhD, Merit Kullinger, MD PhD, Ola Andersson, MD PhD, Ove Axelsson, MD PhD, Pihla Kuusela, MD PhD, Sandra Holmström, MD, Sebastian Brusell Gidlöf, MD PhD, Sofie Graner, MD PhD, Sophia Brismar Wendel, MD PhD, Susanne Hesselman, MD PhD, Verena Sengpiel, MD, PhD, Ylva Carlsson, MD PhD, Ylva Carlsson, MD, PhD, Åsa Leijonhufvud, MD PhD, Åsa Ponten, MD PhD |
2020-06-22 |
| COVIDOLIP: Lipid Metabolism in COVID-19 Severe Pneumonia Compared With Severe Pneumonia Caused by Other Pathogen |
Coronavirus disease 19 infection, Obesity, Sepsis, Viral pneumonia |
biological assays alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire Dijon |
|
France |
2020-04-07 |
2020-05-07 |
COVIDOLIP, NCT04435223, NGUYEN AOIC 2020 |
Phase Not Applicable |
Completed |
1 |
1 Month |
62 |
|
2020-06-24 |
| Effect of convalescent plasma in COVID-19 patients |
Coronavirus disease 19 infection |
Convalescent Plasma alone, Standard of Care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Institute of Liver and Biliary Sciences, India |
|
India |
2020-06-18 |
|
CTRI/2020/06/025803 |
Phase 3 Clinical |
Recruiting |
3 |
|
400 |
Dr Meenu Bajpai, Dr Suresh kumar, Dr Vikas Dogra |
2020-06-22 |
| CoVPN 5001: A Study of Immune Responses to the Virus That Causes COVID-19 |
Coronavirus disease 19 infection |
sample collection alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Institute of Allergy and Infectious Diseases |
|
Malawi, Mozambique, Botswana, Peru, Zambia, US, Zimbabwe, Argentina, Brazil, South Africa, Tanzania, Mexico, Kenya |
2020-06-11 |
2021-01-31 |
5UM1AI068614-14, COVPN 5001, CoVPN 5001, NCT04431414 |
Phase Not Applicable |
Recruiting |
62 |
7 Months |
800 |
CRS Coodinator, CRS Coordinator, CRS Coorindator, CRS Leader, Clinical Trials Manager, Protocol Team Leader, Will Hahn |
2020-06-18 |
| A case report to evaluate the efficacy of recombinant tissue plasminogen activator (rt-PA) and tocilizumab in patients with COVID-19 |
Coronavirus disease 19 infection, Respiratory failure, Thrombosis |
recombinant tissue plasminogen activator (rt-PA) alone, tocilizumab alone |
|
Male, Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University General Hospital of Larissa |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
1 |
|
2020-06-18 |
| COVIT-EHPAD: COVID-19 and Vitamin D in Nursing-home |
Coronavirus disease 19 infection |
vitamin D3 alone |
|
Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital, Angers |
|
France |
2020-03-15 |
2020-05-15 |
2020/67, COVIT-EHPAD, NCT04435119 |
Phase Not Applicable |
Completed |
1 |
2 Months |
96 |
Cédric ANNWEILER, MD, PhD |
2020-06-22 |
| A retrospective study to evaluate the viral kinetics and factors associated with viral clearance during lopinavir/ritonavir-based combination treatment in non-severe COVID-19 patients |
Coronavirus disease 19 infection |
lopinavir + ritonavir alone |
HIV protease inhibitor |
|
Shanghai Jiao Tong University |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
64 |
|
2020-06-21 |
| The Utility of Camostat Mesylate in Patients With COVID-19 Associated Coagulopathy (CAC) and Cardiovascular Complications |
Blood clotting disorder, Coronavirus disease 19 infection, Deep vein thrombosis, Heart injury, Hypoxia, Lung embolism |
camostat mesylate alone |
Serine protease inhibitor, Transmembrane serine protease 2 inhibitor, Trypsin inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Yale University |
Ono Pharmaceutical Co Ltd |
US |
2020-08-01 |
2021-07-30 |
2000028279, NCT04435015 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
11 Months |
200 |
Arpita Neogi, MS, Arya Mani, MD |
2020-06-18 |
| Local application of Povidone Iodine solution in nose and oral gargle for house hold contacts of COVID19 cases |
Coronavirus disease 19 infection |
gargle alone, povidone iodine alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
All India Institute of Medical Sciences, Mangalagiri |
|
India |
2020-06-30 |
|
CTRI/2020/06/025928 |
Phase Not Applicable |
Recruiting |
2 |
|
204 |
Dr Limalemla Jamir, Dr Sumita Shankar, Dr Vivekanand Kattimani |
2020-06-19 |
| Maraviroc in SARS-CoV-2 |
Coronavirus disease 19 infection, Viral pneumonia |
maraviroc alone |
CCR5 chemokine antagonist, CD4 agonist, HIV-1 gp120 protein inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Rhode Island Hospital |
|
US |
2020-09-30 |
2020-12-31 |
1611471-1, NCT04435522 |
Phase 0 Clinical |
Not yet recruiting |
1 |
3 Months |
16 |
Anshul Parulkhar, MD, Neel S Belani, MD, Philip A Chan, MD |
2020-06-19 |
| Remote-by-Default Care in the COVID-19 Pandemic |
Coronavirus disease 19 infection |
interview alone, remote telephone conversation alone, remote video conversation alone, virtual ethnography alone |
|
|
University of Oxford |
Nuffield Trust, University of Plymouth |
UK |
2020-06-01 |
2021-11-30 |
283196, NCT04435041 |
Phase Not Applicable |
No longer recruiting |
1 |
18 Months |
1 |
|
2020-06-22 |
| A medical records based retrospective study of novel coronavirus pneumonia (COVID-19) patients |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
Renmin Hospital of Wuhan University, West China Hospital |
Ministry of Science and Technology of the People´s Republic of China |
China |
2020-06-18 |
2021-06-18 |
ChiCTR2000033782 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
1400 |
Jirong Yue |
2020-06-19 |
| Compassionate Use of Opaganib in Patients With Coronavirus Disease 2019 (COVID-19) |
Coronavirus disease 19 infection |
opaganib alone, standard of care alone |
Dihydroceramide delta 4 desaturase inhibitor, Sphingosine kinase 2 inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shaare Zedek Medical Center |
|
Israel |
2020-04-03 |
2020-05-15 |
0123-20- SZMC, NCT04435106 |
Phase Not Applicable |
Completed |
1 |
1 Month |
23 |
|
2020-06-19 |
| Efficacy and Safety of Nitazoxanide for Post Exposure Prophylaxis of COVID-19 |
Coronavirus disease 19 infection |
nitazoxanide (Viranitta) alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Azidus Brasil |
Farmoquimica SA |
Brazil |
2020-06-30 |
2020-08-31 |
NCT04435314, NITFQM0620OR |
Phase 2 Clinical |
Not yet recruiting |
1 |
2 Months |
200 |
Luciana Ferrara, Marcelo Fonseca, MD, Reginaldo Raimundo Fujita |
2020-06-23 |
| A case-study to evaluate the effects of using high dose oral and/or iv glutathione in the treatment of two patients with dyspnea secondary to COVID-19 pneumonia |
Coronavirus disease 19 infection, Dyspnea, Pneumonia |
glutathione alone |
|
|
Hudson Valley Healing Arts Center |
|
US |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
2 |
|
2020-06-19 |
| Role of Herbal Immunomodulators in mild COVID-19 confirmed cases |
Coronavirus disease 19 infection |
Bresol plus Septilin |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Himalaya Drug Co |
|
India |
2020-06-19 |
|
CTRI/2020/06/025801, HDC/CP/PP/037/2020 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
|
40 |
Dr C R Jayanthi, Dr Palaniyamma D, Dr Soorya Narayan H |
2020-06-22 |
| Study on predictors of novel coronavirus pneumonia (COVID-19) elderly patients |
Coronavirus disease 19 infection, Sarcopenia, Viral pneumonia |
|
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
West China Hospital |
Ministry of Science and Technology of the People´s Republic of China |
China |
2020-06-18 |
2020-09-01 |
ChiCTR2000033781 |
Phase Not Applicable |
Not yet recruiting |
1 |
2 Months |
114 |
Jirong Yue, Yao Ma |
2020-06-19 |
| A Phase I/II study to evaluate its tolerability and activity in COVID-19 patients with hypoxemic respiratory failure receiving either non-invasive positive pressure ventilation (NIPPV) or mechanical ventilation (MV) |
Coronavirus disease 19 infection, Lung inflammation, Respiratory failure |
Rejuveinix alone, mechanical ventilation alone, non-invasive positive pressure ventilation alone, standard of care alone |
|
|
Reven Pharmaceuticals Inc |
|
|
|
|
|
Phase 1/Phase 2 Clinical |
Planned |
0 |
|
|
|
2020-06-18 |
| Inhaled Ciclesonide for Outpatients With COVID19 |
Coronavirus disease 19 infection |
ciclesonide alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
McGill University Health Center, Research Institute of the McGill University Health Centre |
|
Canada |
2020-06-25 |
2021-03-25 |
2021-6696, NCT04435795 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
9 Months |
454 |
Nicole Ezer, Rola Hamed |
2020-06-19 |
| STORM: Repurposing Old Drugs TO Suppress a Modern Threat: COVID-19 STORM |
Coronavirus disease 19 infection |
doxycycline hyclate alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Temple University |
|
US |
2020-06-22 |
2021-07-31 |
NCT04433078, STORM, THE STORM TRIAL |
Phase 2 Clinical |
Recruiting |
2 |
13 Months |
20 |
Arthur M Feldman, MD, PhD, Jamie L Garfield, MD |
2020-06-25 |
| A Phase I Study to Assess BAT-2020 in Hospitalized Patients Infected With SARS-CoV-2 (COVID-19) |
Coronavirus disease 19 infection |
BAT-2020 alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Bio-Thera Solutions Ltd |
|
|
2020-07-20 |
2021-01-18 |
BAT2020-001-CR, NCT04432766 |
Phase 1 Clinical |
Not yet recruiting |
0 |
5 Months |
174 |
|
2020-06-24 |
| A medical records based study for analysis of Tongue Features of novel coronavirus pneumonia (COVID-19) Patients |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
Dahuashan Cabin Hospital, Jiangxia District, Evidence-Based medicine center, Tianjin University of Traditional Chinese Medicine |
Tianjin University of Traditional Chinese Medicine |
China |
2020-06-11 |
2020-06-19 |
ChiCTR2000033780, ChiMCTR2000003393 |
Phase Not Applicable |
No longer recruiting |
1 |
|
500 |
Junhua Zhang, Wentai Pang |
2020-06-19 |
| Association of the Neutrophil/Lymphocyte Ratio With Clinical Complications and Mortality in COVID-19 Patients |
Coronavirus disease 19 infection |
oxygen therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Regional de Alta Especialidad de Ixtapaluca |
Hospital General de Mexico |
Mexico |
2020-03-28 |
2020-05-05 |
NCT04434157, NR-09-2020 |
Phase Not Applicable |
Completed |
1 |
1 Month |
221 |
Christian Ramos Peñafiel,, Omar Ramos-Peñafiel |
2020-06-22 |
| Age and viral load in COVID-19 patients |
Coronavirus disease 19 infection, SARS coronavirus infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
St Marianna University School of Medicine |
|
Japan |
2020-06-18 |
|
UMIN000040816 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
30 |
Tomohiro Katsuta |
2020-06-19 |
| An observational, retrospective study to explore the epidemiological information, clinical characteristics, therapeutic outcomes and temporal progression of laboratory findings in 2019-coronavirus disease (COVID-19) patients exposed to lopinavir |
Coronavirus disease 19 infection |
lopinavir alone |
|
|
The 6th People's Hospital of Hangzhou |
|
China |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
10 |
|
2020-06-18 |
| Role of Ayurveda in Covid 19 management |
Coronavirus disease 19 infection |
Variable regimens including Agnikumara Rasa , Rasona kalka , Samshamani Vati , Shunthi churna , Vyaghryadi kashaya |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
National Health Mission |
|
India |
2020-06-22 |
|
CTRI/2020/06/025800 |
Phase 2 Clinical |
Not yet recruiting |
2 |
|
120 |
Adil Rais |
2020-06-22 |
| Physical Rehabilitation in ICU in ARDS Patients With COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
Rehabilitation program alone, Standard care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Koc University |
|
Turkey |
2020-03-15 |
2020-06-11 |
2020.169.IRB1.037, NCT04435080 |
Phase Not Applicable |
Completed |
1 |
2 Months |
35 |
Ozden Ozyemisci Taskiran, Prof |
2020-06-19 |
| IDRA-COVID19: Ivermectin versus Combined Hydroxychloroquine and Antiretroviral Drugs (ART) Among Asymptomatic COVID-19 infection |
Coronavirus disease 19 infection |
ivermectin alone |
Chloride channel modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Mahidol University |
|
Thailand |
2020-07-31 |
2021-11-30 |
323/2563 (IRB3), IDRA-COVID19, NCT04435587 |
Phase 4 Clinical |
Not yet recruiting |
1 |
16 Months |
80 |
Rujipas Sirijatuphat, MD, Yupin Suputtamongkol, Yupin Suputtamongkol, MD |
2020-06-24 |
| A retrospective study on arbidol monotherapy was superior to lopinavir/ritonavir in treating COVID-19 |
Coronavirus disease 19 infection |
arbidol alone, lopinavir + ritonavir alone |
HIV protease inhibitor |
|
The Third People’s Hospital of Changzhou |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
50 |
|
2020-06-18 |
| RESCUE1-19: Best Supportive Care With or Without Low Dose Whole Lung Radiation Therapy for the Treatment of COVID-19 |
Coronavirus disease 19 infection |
Low Dose Radiation Therapy (LDRT) alone, best supportive care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Emory University |
|
US |
2020-06-12 |
2022-05-30 |
NCI-2020-04061, NCT04433949, P30CA138292, RAD5049-20, RESCUE1-19, STUDY00000781 |
Phase 3 Clinical |
Recruiting |
1 |
23 Months |
52 |
Allyson Anderson, Autumn Lunceford, Clayton B Hess, MD, MPH, Clayton B. Hess, MD,MPH, Mohammad K Khan, MD, PhD, Mohammad K. Khan, MD, PhD |
2020-06-19 |
| Ketotifen: as a Cardioprotective Agent in Breast Cancer Patients Receiving Anthracycline-containing Chemotherapy |
Breast tumor, Cardiotoxicity drug-induced, Coronavirus disease 19 infection |
anthracycline-containing chemotherapy alone, ketotifen alone |
Histamine H1 receptor antagonist |
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Horus University (EG) |
|
Egypt |
2019-01-14 |
2019-08-13 |
1890-1-2019, NCT04435028 |
Phase Not Applicable |
Completed |
1 |
7 Months |
111 |
Hosny ahmed elewa |
2020-06-22 |
| The effect of vitamin C and E in the treatment and clinical course of patients with SARS-COV2 (COVID-19) |
Coronavirus disease 19 infection |
hydroxychloroquine diet alone, Variable regimens including hydroxychloroquine sulfate , lopinavir + ritonavir , vitamin C , vitamin E |
HIV protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Isfahan University of medical Sciences |
|
Iran |
2020-04-20 |
|
IR.MUI.MED.REC.1399.047, IRCT20180425039414N3 |
Phase 2/Phase 3 Clinical |
No longer recruiting |
1 |
|
80 |
Atousa Hakamifard, Shghayegh Haghjoo Javanmard |
2020-06-19 |
| A multinational registry analysis of the use of hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19 |
Coronavirus disease 19 infection |
chloroquine alone, hydroxychloroquine alone, macrolide alone, chloroquine plus hydroxychloroquine |
|
|
Harvard Medical School |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
96032 |
|
2020-06-18 |
| Evaluating the Efficacy and Safety of Bromhexine Hydrochloride Tablets in Treating Pediatric novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Standard treatment alone, bromhexine hydrochloride alone |
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Children's Hospital of Zhejiang University School of medicine |
Zhejiang Wanbang Pharmaceutical Co Ltd |
China |
2020-02-12 |
2020-12-31 |
ChiCTR2000033774 |
Phase 4 Clinical |
Not yet recruiting |
1 |
10 Months |
30 |
Qingqing Wang, Zhimin Chen |
2020-06-19 |
| Treatment With Investigational Convalescent Plasma and Measure Antibody Levels in Patients Hospitalized With COVID-19 |
Coronavirus disease 19 infection |
Anti-SARS-CoV-2 convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of New Mexico |
|
US |
2020-04-28 |
2025-04-28 |
20-227, NCT04434131 |
Phase 2 Clinical |
Recruiting |
1 |
60 Months |
30 |
Greg Mertz, MD, Michelle Harkins, MD |
2020-06-19 |
| A retrospective, single center study on treatment response of tocilizumab in COVID-19 |
Coronavirus disease 19 infection |
tocilizumab alone |
|
|
Huazhong University of Science and Technology |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
15 |
|
2020-06-18 |
| Clinical study on the effect of Keganliyan oral liquid on the relief of pharyngeal symptoms of novel coronavirus pneumonia (COVID-19) in convalescence, suspected patients and other susceptible populations |
Coronavirus disease 19 infection |
Keganliyan liquid alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Maoming Affiliated Hospital of Southern Medical University |
|
China |
2020-06-15 |
2020-12-31 |
ChiCTR2000033745 |
Phase 4 Clinical |
Not yet recruiting |
1 |
6 Months |
240 |
Guanying Hu, Yaocai Li |
2020-06-19 |
| A Real-life, case-series study to report preliminary data obtained with anti-complement C5 therapy with eculizumab in COVID-19 patients admitted to intensive care unit (ICU) of ASL Napoli 2 Nord |
Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia |
eculizumab alone, enoxaparin sodium alone, non-invasive ventilation alone, vitamin C alone, Variable regimens including ceftriaxone , hydroxychloroquine , lopinavir + ritonavir |
Complement C5 factor inhibitor, HIV protease inhibitor, Low molecular weight heparin |
|
Santa Maria delle Grazie, Pozzuoli |
|
|
|
|
|
Phase 4 Clinical |
Status not specified |
0 |
|
4 |
|
2020-06-25 |
| A study for long-term prognosis in hospitalized novel coronavirus pneumonia (COVID-19) patients |
Coronavirus disease 19 infection |
|
|
|
China-Japan Friendship Hospital, Wuhan Jinyintan Hospital |
China Academy of Chinese Medical Sciences |
China |
2020-05-01 |
2021-05-01 |
ChiCTR2000033723 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
2500 |
LIU YING, Zhang DY, Huang CL, Cao B |
2020-06-19 |
| Seroconversion Among Staff at a Large Acute Care Hospital in Denmark During the COVID-19 Pandemic |
Coronavirus disease 19 infection |
biological sampling alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Nordsjaellands Hospital |
Nykøbing Falster County Hospital, University of Oxford |
Denmark |
2020-03-27 |
2025-08-01 |
JOURNAL-NR.: H-20022312, NCT04431310 |
Phase Not Applicable |
Recruiting |
2 |
64 Months |
300 |
Fischer, Gry St-Martin, md, Thea K Fischer, Thea K Fischer, professor |
2020-06-19 |
| CARAVAN: Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of Remdesivir (GS-5734) in Participants From Birth to < 18 Years of Age With Coronavirus Disease 2019 (COVID-19) |
Coronavirus disease 19 infection |
remdesivir alone |
COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator |
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Gilead Sciences Inc |
|
Europe, US |
2020-06-30 |
2020-12-31 |
2020-001803-17, CARAVAN, GS-US-540-5823, NCT04431453 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
6 Months |
52 |
Gilead Clinical Study Information Center, Gilead Study Director |
2020-06-19 |
| An observational study to evaluate the pharmacokinetics of favipiravir in patients with severe COVID-19 who were admitted to the intensive care unit and placed on mechanical ventilation |
Coronavirus disease 19 infection |
favipiravir alone |
RNA polymerase inhibitor |
|
Kobe City Medical Center General Hospital, Kobe Gakuin University |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
7 |
|
2020-06-18 |
| Assessment of the Effectiveness of Vibroacoustic Therapy for Respiratory Failure Caused by COVID 19 |
Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure, Viral pneumonia |
VibroLUNG alone, vibroacoustic therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Astana Medical University |
|
Kazakhstan |
2020-03-22 |
2021-02-01 |
ASTANAMU, NCT04435353 |
Phase Not Applicable |
Recruiting |
2 |
10 Months |
200 |
Irina Mukatova, MD, Irina Mukatova, PhD, Ivan Vahrushev, Dr, Mukatova Irina |
2020-06-19 |
| Impact of Cancellation of Non-urgent Surgical Cases on Patients During the COVID-19 Pandemic |
Coronavirus disease 19 infection |
|
|
|
Mansoura University |
|
Egypt |
2020-07-01 |
2020-12-01 |
NCT04433312, SURG RES COL 2 |
Phase Not Applicable |
Not yet recruiting |
1 |
5 Months |
10000 |
Ahmed M Elsheikh, MD,MBA,CMQOE, Hosam Hamed, MD, MSc, PhD, Mostafa M Shalaby, MD, MSc, PhD, Mostafa Shalaby, MD, MSc, PhD |
2020-06-25 |
| Study to Assess VPM-1002 in Reducing Hospital Admissions and/or Severe Respiratory Infectious Diseases in Elderly in COVID-19 Pandemic |
Coronavirus disease 19 infection, Respiratory tract infection |
VPM-1002 alone |
Listeriolysin stimulator |
Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Max-Planck Gesellschaft zur Förderung Der Wissenschaften eV, Vakzine Projekt Management GmbH |
FGK Clinical Research GmbH |
Germany |
2020-06-30 |
2021-05-31 |
2020-001675-33, NCT04435379, VPM1002-DE-3.07COV |
Phase 3 Clinical |
Recruiting |
4 |
11 Months |
2038 |
Clinical Trial Information, Leander Grode, Dr. rer. nat. |
2020-06-19 |
| PEDONCOVID: COVID-19 in Pediatric Oncology and Hematology Centers in France |
Cancer, Coronavirus disease 19 infection |
|
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Caen University Hospital |
|
France |
2020-04-27 |
2023-04-27 |
20-065, NCT04433871, PEDONCOVID |
Phase Not Applicable |
Recruiting |
1 |
36 Months |
300 |
Jérémie M Rouger-Gaudichon, MD, PhD, Jérémie Rouger-Gaudichon, MD, PhD |
2020-06-19 |
| PrimaryCovCare: Ambulatory healthcare models and processes during the ongoing SARS-CoV-2 pandemic (COVID-19) |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Heidelberg |
|
Germany |
2020-06-17 |
|
DRKS00022224, PrimaryCovCare, S-418/2020 |
Phase Not Applicable |
Recruiting |
1 |
|
1000 |
Amanda Breckner, Catharina Roth, Michel Wensing, Sandra Stengel |
2020-06-19 |
| To evaluate the efficacy of diammonium glycyrrhizinate in combination with vitamin C in patient with COVID-19 |
Coronavirus disease 19 infection |
diammonium glycyrrhizinate plus vitamin C |
|
Female |
National Institute of Allergy and Infectious Diseases, National Institute of General Medical Sciences, National Institutes of Health, US Department of Health and Human Services |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
1 |
|
2020-06-18 |
| A clinical trial of VLP vaccine (COVID-19), Saiba for the potential prevention of SARS-CoV-2 infection (COVID-19) |
Coronavirus disease 19 infection |
VLP vaccine (COVID-19), Saiba alone |
COVID19 Spike glycoprotein modulator |
|
Saiba GmbH |
|
|
2020-12-31 |
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-06-18 |
| IFORS: A Study to Compare the Efficacy and Safety of Different Doses of Ivermectin for COVID-19 |
Coronavirus disease 19 infection, Respiratory disease, Respiratory tract infection |
ivermectin alone |
Chloride channel modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fundação Universidade Federal De São Carlos |
|
Brazil |
2020-07-01 |
2021-07-01 |
IFORS, IFORS, NCT04431466 |
Phase 2 Clinical |
Not yet recruiting |
1 |
12 Months |
64 |
Henrique Pott Junior, Henrique Pott Junior, MD PhD |
2020-06-19 |
| Cardiovascular Implications of COVID-19 |
Coronavirus disease 19 infection, Heart injury |
[1-13C] pyruvate alone, multiparametric cardiac magnetic resonance imaging (CMR) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Texas Southwestern Medical Center |
|
|
2020-06-30 |
2020-10-31 |
NCT04435457, STU-2020-0359 |
Phase Not Applicable |
Not yet recruiting |
0 |
4 Months |
70 |
Carolyn Kelly, RN, MPH, CCRC, Justin L Grodin, MD, MPH |
2020-06-19 |
| To observe the effect of Siddha formulation Kabasura kudineer in COVID 19 patients |
Coronavirus disease 19 infection |
Kabasura kudineer alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Government Theni Medical College and Hospital, Ministry of Ayush |
|
India |
2020-06-24 |
|
CTRI/2020/06/025874 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
60 |
Dr C Anbarasi, Dr P Sankararaj |
2020-06-19 |
| A phase II/III study of COVAX-19 in prevention of COVID-19 |
Coronavirus disease 19 infection |
Covax-19 alone |
Coronavirus spike glycoprotein inhibitor |
|
Vaxine Pty Ltd |
|
|
2020-12-31 |
|
|
Phase 2/Phase 3 Clinical |
Planned |
0 |
|
|
|
2020-06-19 |
| Study of AYUSH KWATH in quarantine persons |
Coronavirus disease 19 infection |
Ayush Kwath alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Dr. Sarvepalli Radhakrishnan Rajasthan Ayurveda University |
|
India |
2020-06-17 |
|
CTRI/2020/06/025779 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
50 |
Prof Dr Abhimanyu Kumar |
2020-06-19 |
| A case series, retrospective study on 18F-FDG PET/CT findings of COVID-19 infection |
Coronavirus disease 19 infection, Respiratory disease |
18F-FDG alone, positron emission tomography/computed tomography alone |
|
|
Chang Gung Memorial Hospital, Huazhong University of Science and Technology, Hubei Province Pharmaceutical Industry Research Institute |
|
China |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
4 |
|
2020-06-18 |
| A retrospective, multicenter, cohort study to describe the association between use of hydroxychloroquine, with or without azithromycin, and clinical outcomes among hospital inpatients diagnosed with coronavirus disease 2019 (COVID-19) |
Coronavirus disease 19 infection |
azithromycin alone, hydroxychloroquine alone, azithromycin plus hydroxychloroquine |
|
|
UAlbany School of Public Health |
|
US |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
1438 |
|
2020-06-18 |
| A prophylactic interventional study to determine the possible protective effect of Siddha Polyherbal formulation Kabasura Kudineer / Nilavembu kudineer against the COVID-19 on intermittent, month-long consumption by Highrisk population and frontline workers in Tamil Nadu, India |
Coronavirus disease 19 infection |
Standard of Care alone, Kabasura Kudineer plus Nilavembu kudineer |
|
|
National Institute of Siddha |
|
India |
2020-06-15 |
|
CTRI/2020/06/025769 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
500 |
Dr G J Christian, Dr R Meenakumari |
2020-06-19 |
| TOCCIP: COVID-19 Critically Ill Patients Evolution After Medical Transport by Train From Paris Intensive Care Units to West of France Intensive Care Units |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Rennes University Hospital |
|
France |
2020-06-30 |
2020-09-30 |
35RC20-3091-TOCCIP, NCT04433325, TOCCIP |
Phase Not Applicable |
Not yet recruiting |
2 |
3 Months |
150 |
Anne Ganivet, Arnaud THILLES, Benoît Painvin, Nicolas Mevel, Stéphane ERHMANN |
2020-06-19 |
| Impact of COVID-19 on Laboratory Professionals-Early Evidences from a Survey at a Clinical Chemistry Laboratory in a Developing Country |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Aga khan University |
|
Pakistan |
2020-06-04 |
2020-06-14 |
ChiCTR2000033899 |
Phase Not Applicable |
No longer recruiting |
1 |
|
64 |
Sibtain Ahmed |
2020-06-19 |
| An open-label, Randomized Controlled Clinical trial to Evaluate the Safety and Efficacy of selected Siddha formulations in patients diagnosed with COVID-19 |
Coronavirus disease 19 infection |
siddha formulation alone, Variable regimens including Kabasura kudineer , Nellikai Ilagam , amukkara churnam |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Chengalpattu Medical College, National Institute of Siddha |
|
India |
2020-06-20 |
|
CTRI/2020/06/025768 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
200 |
Dr G J CHRISTIAN, Dr MEENAKUMARI R |
2020-06-19 |
| Natural Language Processing (NLP) Analysis of Free Text Notes to Investigate Coronavirus (COVID-19) |
Coronavirus disease 19 infection, Renal injury, Thromboembolism |
electronic health record (EHR) alone, natural language processing techniques alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cambridge University Hospitals NHS Foundation Trust |
University of Cambridge |
UK |
2020-07-31 |
2021-07-31 |
A095625, NCT04432961 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
200 |
Dr Sapna Trivedi |
2020-06-19 |
| An interim Doherty Report on SARS-CoV-2 antibodies based on Wondfo test (serology-based COVID-19 POC test) |
Coronavirus disease 19 infection |
Wondfo test (serology-based COVID-19 POC test) alone |
|
|
Cellmid Ltd |
|
Australia |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
137 |
|
2020-06-18 |
| The Use of Lung Ultrasonography in COVID-19 Patients |
Coronavirus disease 19 infection, Respiratory failure |
mechanical ventilator settings and position alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Gaziosmanpasa Taksim Research and Education Hospital |
|
Turkey |
2020-05-26 |
2020-06-26 |
GAZIOSMANPASA, NCT04432051 |
Phase Not Applicable |
Recruiting |
1 |
1 Month |
100 |
SİBEL BEKTAŞ |
2020-06-19 |
| Community Health Workers Against COVID19 |
Anxiety disorder, Coronavirus disease 19 infection |
community health worker support alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universitaet Gent |
|
Belgium |
2020-05-21 |
2020-10-30 |
BC-07744., NCT04426305 |
Phase Not Applicable |
Recruiting |
1 |
5 Months |
140 |
|
2020-06-19 |
| A Study of Favipiravir in Patients with Mild to Moderate Coronavirus Disease (COVID-19) |
Coronavirus disease 19 infection |
favipiravir alone, supportive care alone |
RNA polymerase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Cipla Ltd |
|
India |
2020-06-17 |
|
CP/04/20, Version No. 1.0, CTRI/2020/06/025799 |
Phase 3 Clinical |
Not yet recruiting |
8 |
|
156 |
Dr Ameet Dravid, Dr Anand Kumar, Dr Atul Patel, Dr Jaideep Gogtay, Dr Meenakshi Bhattacharya, Dr Raja Dhar, Dr Rohidas Borse, Dr Sandesh Sawant, Dr Shreepad Bhat, Dr Vasant Nagvekar, Mr Abhijit Vaidya |
2020-06-19 |
| ICON STUDY: A Clinical trial to establish the appropriate line of management of non-muscle invasive bladder cancers who have had their intravesical BCG therapy interrupted |
Bladder cancer, Coronavirus disease 19 infection |
BCG alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
All India Institute of Medical Sciences, All India Institute of Medical Sciences Bhubaneswar, Christian Medical College, Vellore, India, Jawaharlal Institute of Postgraduate Medical Education Research, Postgraduate Institute of Medical Education and Research, king george's medical university |
|
India |
2020-06-18 |
|
CTRI/2020/06/025798, ICON STUDY |
Phase 4 Clinical |
Not yet recruiting |
10 |
|
70 |
Amlesh Seth, Aneesh Srivastava, Dr Tushar Aditya Narain, Gautam Ram Choudhary, Manikandan Ramanidhatharan, Prasant Nayak, Sameer Trivedi, Santosh Kumar, Satya Narayan Sankhwar, Shrawan Kumar Singh, Tushar Aditya Narain |
2020-06-19 |
| Quality of Life During COVID-19 Lockdown |
Coronavirus disease 19 infection, Pain |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Cancer Institute, Jhajjar, AIIMS |
|
India |
2020-06-13 |
|
CTRI/2020/06/025797 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
|
Anuja Pandit |
2020-06-19 |
| Effect of aragwadhadi kwath (kadha in Hindi) in treatment of mild coronavirus disease |
Coronavirus disease 19 infection |
aragwadhadi kwath alone, standard care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Sanjivani Aryuvedic Centre |
|
India |
2020-06-15 |
|
CTRI/2020/06/025796 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
90 |
Dr Sunil Panjwani, Vaidhya Tushar Trivedi |
2020-06-19 |
| Effects of Lockdown during Corona Pandemic on Children with Neurodevelopmental Disorders-A Questionnaire Based Survey |
Attention deficit hyperactivity disorder, Autism, Coronavirus disease 19 infection |
question based survey alone |
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs) |
Army Hospital Research and Referral |
|
India |
2020-06-15 |
|
CTRI/2020/06/025795 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
150 |
J N Goswami, Shuvendu Roy |
2020-06-19 |
| Effect of anakinra in treatment of COVID-19 |
Coronavirus disease 19 infection |
anakinra, Persisgen alone, recommended COVID-19 treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Persisgen Par Co |
|
Iran |
2020-06-21 |
|
IR.SBMU.PHARMACY.REC.1399.051, IRCT20120703010178N20 |
Phase 3 Clinical |
Recruiting |
1 |
|
30 |
Amir Behnam Kharazmi, Amir Hossein Karagah, Mohammad Sistanizad, Omid Moradi |
2020-06-23 |
| A Study to Assess the Effect of Beckman Coulter SARS-CoV-2 Antibody Test in Patients with COVID-19 |
Coronavirus disease 19 infection |
Beckman Coulter SARS-CoV-2 antibody test alone |
|
|
Henry Ford Health System |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
|
|
2020-06-18 |
| PRO-SERO-COV: Serological Response to SARS-Cov-2 Virus in Personnel of the Institut Bergonie in the Context of the COVID-19 Pandemic |
Coronavirus disease 19 infection |
blood sampling alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Institut Bergonie |
|
France |
2020-06-30 |
2021-12-31 |
2020-A01355-34, IB 2020-01, NCT04426006, PRO-SERO-COV |
Phase Not Applicable |
Not yet recruiting |
1 |
18 Months |
1000 |
Brice RICHEZ, MD, Simone MATHOULIN-PELISSIER, MD, PhD |
2020-06-21 |
| TA/SARS-Cov2: Is Adipose Tissue a Reservoir for SARS-Cov2 Spread in Covid-19 Patients? |
Coronavirus disease 19 infection |
biopsies of subcutaneous adipose tissue alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire De Nice |
|
France |
2020-07-01 |
2021-07-09 |
20-PP-15, NCT04427878, TA/SARS-Cov2 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
5 |
Berengère Chignon-Sicard, PH, Vanina OLIVERI, PM |
2020-06-21 |
| CIO: Impact of COVID-19 Lockdown on Obesity and Eating Behaviors |
Acute stress disorder, Anxiety disorder, Binge eating disorder, Coronavirus disease 19 infection, Depression, Obesity |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospices Civils De Lyon |
|
France |
2020-06-30 |
2020-09-30 |
2020-A01616-33, 69HCL20-0516, CIO, NCT04431284 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
46 |
Emmanuel DISSE, MD, Martine LAVILLE, MD |
2020-06-19 |
| ABACCuS: Antibody-Level Based Analysis of COVID Convalescent Serum |
Coronavirus disease 19 infection |
COVID-19 convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
William Beaumont Hospitals |
|
US |
2020-06-30 |
2021-08-31 |
2020-198, ABACCuS, NCT04432272 |
Phase 2 Clinical |
Not yet recruiting |
1 |
14 Months |
500 |
Matthew Sims, MD, Matthew Sims, MD PhD, Maureen Cooney, RN, BSN |
2020-06-19 |
| Favipiravir effectiveness in patients undergoing COVID19 Acute respiratory distress syndrome (ARDS) |
Coronavirus disease 19 infection, Respiratory distress syndrome |
favipiravir alone |
RNA polymerase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Masih Daneshvari Hospital |
|
Iran |
2020-03-20 |
2020-05-21 |
IR.SBMU.NRITLD.REC.1399.041, IRCT20150107020592N26 |
Phase 3 Clinical |
Completed |
1 |
2 Months |
20 |
DR Reza Masoodi, Seyed Mohammad Reza Hashemian, Seyyed Mohammadreza Hashemian |
2020-06-19 |
| ANIF1 effect on COVID-19 |
Coronavirus disease 19 infection |
ANIF1 alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Mazandaran University of Medical Sciences |
|
Iran |
2020-06-09 |
|
IR.MAZUMS.REC.1399.067, IRCT20190727044343N3 |
Phase 2/Phase 3 Clinical |
No longer recruiting |
1 |
|
60 |
Lotfollah Davoodi |
2020-06-23 |
| Prone Positioning on Admission for Hospitalized COVID-19 Pneumonia Protocol |
Coronavirus disease 19 infection, Viral pneumonia |
Prone Positioning alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Poudre Valley Health System |
|
US |
2020-06-30 |
2020-12-31 |
20-6034, NCT04424797 |
Phase Not Applicable |
Recruiting |
3 |
6 Months |
100 |
Adam Jaskowiak, Lucie Uncapher, Lucie Uncapher, MD, Research Manager, Sara Twombly, MACI CCRC |
2020-06-21 |
| Treatment of COVID-19 whit vitamin A |
Coronavirus disease 19 infection |
vitamin A, Ovigel Company alone |
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ghoum University of Medical Sciences |
|
Iran |
2020-05-04 |
2020-06-13 |
IR.MUQ.REC.1399.045, IRCT20200314046774N1 |
Phase 3 Clinical |
Completed |
1 |
1 Month |
94 |
Majid Farhadifard |
2020-06-22 |
| Combined effects of Extracts on Covid-19 |
Coronavirus disease 19 infection |
herbal teas alone |
|
|
Shiraz University of Medical Sciences |
|
Iran |
2020-06-21 |
|
IR.SUMS.REC.1399.179, IRCT20200508047345N1 |
Phase Not Applicable |
No longer recruiting |
1 |
|
100 |
Mohammad Jamal Saharkhiz |
2020-06-24 |
| I-GLOBAL: Validation of an Immunochromatographic Assay for IgG/IgM Antibodies to 2019- nCoV |
Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia |
IgG/IgM rapid test cassette alone, immunochromatographic assay alone, polymerase chain reaction alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
European Institute of Oncology |
ASST Papa Giovanni XXIII, Azienda Ospedale Niguarda Cà Granda, Company Socio - Cremona Territorial Health, Fondazione IRCCS Istituto Neurologico Carlo Besta |
Italy |
2020-04-15 |
2020-12-31 |
I-GLOBAL, I-GLOBAL, NCT04434417 |
Phase Not Applicable |
Recruiting |
5 |
8 Months |
1000 |
Alberto Zambelli, MD, Antonio Marra, MD, Atanasio Nonis, PhD, Daniele Generali, MD, Francesco Di Meco, MD, Giuseppe Curigliano, MD, Giuseppe Curigliano, MD, PhD, Salvatore Siena, MD |
2020-06-18 |
| Prone position effectiveness in Non invasive ventilation of covid-19 patients undergoing respiratory failure |
Coronavirus disease 19 infection, Respiratory failure |
non-invasive ventilation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shahid Beheshti University of Medical Sciences |
|
Iran |
2020-03-20 |
|
IR.SBMU.NRITLD.REC.1399.009, IRCT20150107020592N25 |
Phase 3 Clinical |
No longer recruiting |
1 |
|
30 |
Seyed Mohammad Reza Hashemian, Seyed Mohammad reza hashemian, Seyyed Mohammadreza Hashemian |
2020-06-23 |
| Treatment of Covid-19 patients with convalescent plasma |
Coronavirus disease 19 infection |
convalescent covid-19 plasma therapy alone |
|
|
Iranian blood transfusion organization |
|
Iran |
2020-05-25 |
|
IR.TMI.REC.1399.003, IRCT20200525047562N1 |
Phase 3 Clinical |
Recruiting |
2 |
|
100 |
Hamid Reza Kouhpayeh, Mandana Pouladzadeh, Peyman Eshghi, Saeed Mohammadi, Shamsi Okati |
2020-06-22 |
| A Gamified Network for Surgical Education During COVID-19: A Randomized Controlled Trial |
Coronavirus disease 19 infection |
Peer-learning alone, Peer-learning with expert feedback alone, Self-learning alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universite De Montreal |
|
|
2020-06-30 |
2020-06-30 |
CERSES 20-068-D, NCT04425499 |
Phase Not Applicable |
Not yet recruiting |
0 |
|
60 |
Érica Patocskai, Assistant professor |
2020-06-22 |
| Recruit Blood Donors Via SMS During Epidemic of COVID-19 #Second Repeat Trial# |
Coronavirus disease 19 infection |
blood donation SMS alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Guangzhou Blood Center |
|
China |
2020-06-13 |
2020-06-30 |
NCT04431180, RECRUIT BLOOD DONORS VIA SMS 3 |
Phase Not Applicable |
Recruiting |
1 |
|
403535 |
|
2020-06-23 |
| Covid-No-Thank you: Data evaluation of an online symptom and risk detection application for COVID-19 research |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Orthopädische Universitätsklinik Friedrichsheim gGmbH |
University Hospital Magdeburg |
Germany |
2020-04-29 |
|
65/20, Covid-No-Thank you, DRKS00022185, U1111-1252-6946 |
Phase Not Applicable |
Recruiting |
1 |
|
10000 |
Dietmar Urbach, Gutingi-Medical GmbH |
2020-06-22 |
| The effect of pentaglobin in the treatment of critically ill patients with COVID-19 |
Coronavirus disease 19 infection, Respiratory failure |
pentaglobin alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shaheed Beheshti Medical University |
|
Iran |
2020-03-20 |
|
IR.SBMU.NRITLD.REC.1399.014, IRCT20150107020592N27 |
Phase 3 Clinical |
No longer recruiting |
1 |
|
60 |
Dr Seyyed Mohamadreza Hashemian, Seyyed Mohammadreza Hashemian |
2020-06-24 |
| Proper Nutrition And Its Relation To Oral Diseases In Covid -19 Era |
Coronavirus disease 19 infection, Mouth disease |
Proper diet alone, Vitamins alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
October University for Modern Sciences and Arts |
|
Egypt |
2020-06-08 |
2020-06-28 |
12345678, NCT04434014 |
Phase Not Applicable |
Recruiting |
1 |
|
300 |
Lecturer Mona abdelmoteleb, Samah Kamel, A .Prof, Samah Mohamed Kamel, A.Prof, Samah Mohamed Kamel, associate professr, lecturer Mona Abdelmoteleb |
2020-06-18 |
| ASTANA: Oncological Surgery in Times of COVID-19: Effectiveness of Preoperative Screening for Sars-Cov-2 |
Cancer, Coronavirus disease 19 infection |
SARS-CoV-2 PT-PCR test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Instituto Brasileiro de Controle do Cancer |
|
Brazil |
2020-05-11 |
2020-12-31 |
33467320.0.0000.0072, ASTANA, NCT04434261 |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
1500 |
Alayne Yamada, PhD, Andre Lopes, MD |
2020-06-18 |
| Evaluation of the effectiveness of traditional medicine combination based on the Ferula assa-foetida gum - Tragacanth in Participants with Moderate to Severe Coronavirus Disease (COVID-19) |
Coronavirus disease 19 infection |
Ferula assa-foetida gum plus tragacanth |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Mashhad University of Medical Sciences |
|
Iran |
2020-06-19 |
|
IR.MUMS.REC.1399.285, IRCT20200607047675N1 |
Phase 3 Clinical |
Recruiting |
1 |
|
100 |
Dr. Amin Bojdy, Dr. HamidReza Bahrami Taghanaki, Dr. Majid Jafarinejad, Nayereh Esmaeilzadeh, ِDr. Mohsen Tafaghdi |
2020-06-19 |
| Treatment of Severe and Critical COVID-19 Pneumonia With Convalescent Plasma |
Coronavirus disease 19 infection, Viral pneumonia |
anti sars-cov 2 convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
American British Cowdray Medical Center |
|
Mexico |
2020-06-19 |
2020-09-30 |
ABC-20-14, NCT04432103 |
Phase 2 Clinical |
Recruiting |
1 |
3 Months |
36 |
Benjamín Valente, MD MSc DTMH, Francisco Moreno, MD, Irma Hoyo, MD PHD, Paulina Trápaga, MBE |
2020-06-19 |
| An interventional study to evaluate the safety and immune response of a vaccine against Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2, the virus that causes COVID-19 infection) when given to healthy adult participants |
Coronavirus disease 19 infection |
SARS-CoV-2 Sclamp alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
University of Queensland |
Coalition for Epidemic Preparedness Innovations |
Australia |
2020-07-14 |
|
ACTRN12620000674932p, UQ-1-SARS-CoV-2-Sclamp |
Phase 1 Clinical |
Not yet recruiting |
1 |
|
120 |
Dr Paul Griffin |
2020-06-19 |
| CoPE-HCP: COVID19 and Physical and Emotional Wellbeing of HCP |
Anxiety disorder, Coronavirus disease 19 infection, Depression, Psychotic disorder |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Queen Mary University of London |
|
UK |
2020-06-30 |
2021-06-30 |
284686, CoPE-HCP, NCT04433260 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
1050 |
Ajay Gupta, MD, PhD, Ajay Gupta, MD,PhD |
2020-06-18 |
| ACCOLADE: Amnion cells for COVID-19 related respiratory failure |
Coronavirus disease 19 infection, Respiratory failure |
amniotic epithelial cells (hAECs) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Monash Health |
|
Australia |
2020-06-29 |
|
ACCOLADE, ACTRN12620000676910p |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
|
40 |
A/Prof Rebecca Lim, Prof Yahya Shehabi |
2020-06-19 |
| Efficacy of Pentoxifylline as Add-on Therapy in COVID-19 Patients |
Coronavirus disease 19 infection |
pentoxifylline SR alone, standard treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
University of Sadat City |
|
Egypt |
2020-06-13 |
2020-08-30 |
NCT04433988, RC-6-2020 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
2 Months |
200 |
Mahmoud S Abdallah, PhD |
2020-06-18 |
| Perceptions, Representations and Experiences of Septic Isolation of Hospitalized Patients for COVID-19 Infection |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Intercommunal Creteil |
|
France |
2020-07-01 |
2020-07-15 |
ISOCOV, NCT04432922 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
15 |
Alice RAFFETIN, MD |
2020-06-23 |
| In-utero Vascular Accidents in Neonates From COVID-19 Infected Mothers |
Coronavirus disease 19 infection, Fetal growth restriction, Limb development disorder, Premature labor, Spontaneous abortion |
SARS-CoV-2 antibody testing alone |
|
Healthy volunteers accepted |
University of Colorado, Denver, US |
|
US |
2020-07-31 |
2022-07-31 |
20-1399, NCT04431869 |
Phase Not Applicable |
Not yet recruiting |
1 |
24 Months |
200 |
Jose L Diaz-Miron, MD |
2020-06-25 |
| Validation of a Rapid Quantitative Test for Loss of Smell in COVID-19 Subjects |
Coronavirus disease 19 infection, Dysomia |
olfactory device alone, rapid quantitative olfactory smell test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Yale University |
|
US |
2020-06-15 |
2020-10-01 |
2000028259, NCT04431908 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
250 |
R Peter Manes, MD, FACS |
2020-06-18 |
| An Open-Label Randomized Controlled, Proof-of-Concept (PoC) Study to Evaluate the Safety and Efficacy of selected Siddha formulations in patients diagnosed with COVID-19 |
Coronavirus disease 19 infection |
Variable regimens including Amukkara choornam , KS kudineer , Nellikkai ilagam |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Institute of Siddha |
|
India |
2020-06-15 |
|
CTRI/2020/06/025762 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
200 |
Dr G J Christian, Dr R Meenakumari |
2020-06-18 |
| Population based cross-sectional study for COVID 19 prophylaxis with Polyherbal Siddha formulation Kabasura Kudineer / Nilavembu kudineer in containment zones and non containment zones during 2020 pandemic in Tamil Nadu, South India |
Coronavirus disease 19 infection |
Kabasura Kudineer / Nilavembu kudineer alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
National Institute of Siddha |
|
India |
2020-06-15 |
|
CTRI/2020/06/025761 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
10000 |
Dr G J Christian, Dr R Meenakumari |
2020-06-18 |
| A clinical trial to study the effect of drug named Sofosbuvir in hospitalized patients with COVID 19 |
Coronavirus disease 19 infection |
hydroxychloroquine plus sofosbuvir |
Hepatitis C virus NS5B polymerase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Vijaya Medical and Educational Trust |
|
India |
2020-06-17 |
|
CTRI/2020/06/025760 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
50 |
Babu N |
2020-06-19 |
| PoWerS: COVID-19 Psychological Wellbeing for Healthcare Students |
Coronavirus disease 19 infection |
Psychological wellbeing for healthcare workers alone |
|
Healthy volunteers accepted |
University of Nottingham |
|
|
2020-06-13 |
2020-12-30 |
NCT04429828, POWERS_JUNE2020, PoWerS |
Phase Not Applicable |
Not yet recruiting |
0 |
6 Months |
45 |
Holly Blake, PhD |
2020-06-19 |
| Hydroxychloroquine May Reduce Risk of COVID-19 Infection in Rheumatoid Arthritis Patients |
Coronavirus disease 19 infection, Rheumatoid arthritis |
glucocorticoid therapy alone, Variable regimens including hydroxychloroquine , leflunomide , methotrexate , sulfasalazine |
Dihydroorotate dehydrogenase inhibitor, Protein tyrosine kinase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
University of Sadat City |
|
Egypt |
2020-03-20 |
2020-06-20 |
IRB: RC-5-2020, NCT04434118 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
600 |
|
2020-06-18 |
| CAHMP-ED: COVID-19 and the Healthy Minds Program for Educators |
Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression |
Healthy Minds Program Foundations Training alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Wisconsin-Madison |
Center for Healthy Minds, Chan Zuckerberg Initiative, Healthy Minds Innovations |
|
2020-06-10 |
2022-06-30 |
2020-0533, A171600, CAHMP-ED, EDUC/COUNSELING PSYCH, NCT04426318, PROTOCOL APPROVAL 6/4/2020 |
Phase Not Applicable |
Not yet recruiting |
0 |
24 Months |
400 |
Corrina Frye, Simon B Goldberg, PhD |
2020-06-17 |
| A clinical study of nelfinavir in combination with amodiaquine for the treatment of COVID-19 |
Coronavirus disease 19 infection |
amodiaquine plus nelfinavir |
HIV protease inhibitor, HIV-1 protease inhibitor |
|
Norwegian University of Science and Technology (NTNU) |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-06-17 |
| Effect of Auriculotherapy in treatment of COVID-19 |
Coronavirus disease 19 infection |
orchicotherapy alone |
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Shahid Sadoughi University of Medical Sciences and Health Services |
|
Iran |
2020-04-28 |
|
IR.SSU..REC.1399.030, IRCT20180608040007N2 |
Phase Not Applicable |
Recruiting |
1 |
|
70 |
Dr. Masoud Mirzaei, Maryam Mohammadi, Mohammad Bagher Khani |
2020-06-18 |
| Dornase Alpha for the Treatment of COVID-19 |
Coronavirus disease 19 infection |
dornase alfa alone |
Deoxyribonuclease I stimulator, Deoxyribonuclease stimulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Acibadem University |
The Scientific and Technological Research Council of Turkey |
Turkey |
2020-05-25 |
2020-09-25 |
8820, NCT04432987 |
Phase 2 Clinical |
Recruiting |
1 |
4 Months |
60 |
Ercument Ovalı, MD, Ercument Ovalı, Prof. |
2020-06-18 |
| Effect of Atazanavir/Ritonavirin treatment of COViD-19 |
Coronavirus disease 19 infection |
atazanavir sulfate + ritonavir (HIV infection), Mylan Laboratories alone |
HIV protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Alborz University of Medical Science |
|
Iran |
2020-06-14 |
|
IR.ABZUMS.REC.1399.065, IRCT20200504047298N1 |
Phase 3 Clinical |
Recruiting |
1 |
|
100 |
Zeinab Siami |
2020-06-18 |
| ELIKYA COVID: Impact of COVID-19 Infection During Pregnancy on Newborns and Young Children |
Coronavirus disease 19 infection, Pregnancy disorder |
nasal swab test alone, serology test alone |
|
|
Centre Hospitalier Universitaire Saint Pierre |
Institute for Medical Immunology (IMI), Laboratoire Hospitalier Universitaire de Bruxelles |
Belgium |
2020-06-25 |
2024-06-30 |
ELIKYA COVID, ELIKYA COVID, NCT04432779 |
Phase Not Applicable |
Not yet recruiting |
2 |
48 Months |
3000 |
Julie Belhomme, MD, Tessa Goetghebuer, MD, Tessa Goetghebuer, MD PhD, Tessa Goetghebuer, MD, PhD |
2020-06-23 |
| HIBISCUS: A phase II/III pivotal, randomized, placebo-controlled Traumakine study in severely ill COVID-19 patients |
Adult respiratory distress syndrome, Coronavirus disease 19 infection, Influenza virus infection |
FP-1201 alone |
CD73 agonist, Interferon beta ligand |
|
Faron Pharmaceuticals Ltd |
|
US |
|
|
HIBISCUS |
Phase 2/Phase 3 Clinical |
Planned |
1 |
|
350 |
Prof. Daniel Talmor |
2020-06-17 |
| CovImmune 2: Study of the Incidence of SARS-CoV-2 Infection |
Coronavirus disease 19 infection |
blood sampling alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire De Nice |
|
France |
2020-07-15 |
2025-12-31 |
20-PP-14, CovImmune 2, NCT04429594 |
Phase Not Applicable |
Not yet recruiting |
1 |
65 Months |
1000 |
Barbara SEITZ, MCUPH, Barbara SEITZ- POLSKI, Christian PRADIER, barbara SEITZ POLSKI, sonia BOYER SUAVET |
2020-06-18 |
| COVID-19 Versus H1N1: Radiological Challenge During Next Influenza Season Rising |
Coronavirus disease 19 infection, Influenza virus infection, Viral pneumonia |
GE LightSpeed Plus 4 slice CT scanner (USA) alone, Philips Brilliant-16 (USA) alone, Siemens SOMATOM Sensation 64 (Germany) alone, Siemens SOMATOM Emotion 16 alone, Toshiba Aquilion 64 alone, Toshiba Aquilion CXL/CX 128 (USA) alone, high-resolution computed tomography alone |
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Alexandria |
|
Egypt |
2020-05-22 |
2020-06-14 |
IRB (00012098), SN (0304669), NCT04433039 |
Phase Not Applicable |
Completed |
1 |
|
130 |
Ahmed Samir, MD |
2020-06-18 |
| SURG-SAT-19: COVID-19 - Implications on Surgeons' Burnout and Career Satisfaction |
Acute stress disorder, Coronavirus disease 19 infection |
cloud-based software (SurveyMonkey) alone, online survey alone |
|
Healthy volunteers accepted |
Mansoura University |
|
Egypt |
2020-06-15 |
2020-08-31 |
NCT04433286, SURG RES COL 1, SURG-SAT-19 |
Phase Not Applicable |
Not yet recruiting |
1 |
2 Months |
1000 |
Ahmed M Elsheikh, MD,MBA,CMQOE, Hosam Hamed, MD, MSc, PhD, Mostafa Shalaby, MD, MSc, PhD |
2020-06-19 |
| The Development of Pancreatic Injury in the Course of Severe Acute Respiratory Syndrome Coronavirus-2 Infection |
Coronavirus disease 19 infection, Pancreas injury, Viral pneumonia |
biochemical analysis alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Usak University, Turkey |
|
Turkey |
2020-03-01 |
2020-06-12 |
NCT04433754, USAKU-CEVDET2 |
Phase Not Applicable |
Completed |
1 |
3 Months |
500 |
Cevdet Duran |
2020-06-18 |
| Clinical study to evaluate the efficiency of specific antibody against SARS-CoV-2 |
Coronavirus disease 19 infection |
antibody tests alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Yokohama City University |
Japan Agency for Medical Research and Development |
Japan |
2020-06-22 |
|
UMIN000040744 |
Phase Not Applicable |
Recruiting |
1 |
|
5000 |
Mie Tsuchiya, tomoyuki miyazaki |
2020-06-18 |
| Maternal Psychological Implications of Covid-19 Pandemic and Possible Effect on Anesthetic Management |
Coronavirus disease 19 infection |
38-questions questionnaire alone, GAD-7 general anxiety disorder scale alone, PHQ-9 depression scale alone |
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
General and Maternity Hospital of Athens Elena Venizelou |
|
Greece |
2020-05-15 |
2020-12-31 |
MATERNAL COVID 19, NCT04432948 |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
200 |
Georgia Micha, Dr |
2020-06-18 |
| BNP, Serum Troponin and D-dimer as Risk Factors in Patients With COVID-19 |
Coronavirus disease 19 infection |
serum sampling alone |
|
|
Assiut University |
|
Egypt |
2020-07-01 |
2021-09-01 |
CARDIAC MARKERS IN COVID-19, NCT04433026 |
Phase Not Applicable |
Not yet recruiting |
1 |
14 Months |
90 |
Areej Osama Ali Mohammed Saleh, Areej Saleh |
2020-06-19 |
| A clinical study to assess Tempol for the treatment of subjects with COVID-19 |
Coronavirus disease 19 infection |
Tempol (oral, radiotherapy-induced toxicities), Matrix Biomed alone |
Superoxide dismutase modulator |
|
Adamis Pharmaceuticals Corp |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-06-17 |
| Assessment of Mortality Rates in SARS-CoV-2 Infected Populations Treated With Repurposed Medications |
Coronavirus disease 19 infection |
Variable regimens including azithromycin , chloroquine , hydroxychloroquine |
|
|
Tabula Rasa HealthCare Inc |
|
US |
2020-06-15 |
2021-05-31 |
COVID-19_TRHCPRESCRIBEWELLNESS, NCT04432350 |
Phase Not Applicable |
Not yet recruiting |
1 |
11 Months |
50000 |
Pamela Dow, MS, Veronique Michaud, Veronique Michaud, PhD |
2020-06-18 |
| A Phase III trial of COVID-19 vaccine for COVID-19 patients |
Coronavirus disease 19 infection |
COVID-19 vaccine (inactivated, Vero cells/intramuscular), Wuhan Institute of Biological Products/Wuhan Institute of Virology, CAS alone |
|
|
Wuhan Institute of Biological Products Co Ltd |
|
|
|
|
|
Phase 3 Clinical |
Planned |
0 |
|
|
|
2020-06-24 |
| Effect of Opuntia Cactus extract in patients with Covid-19 |
Coronavirus disease 19 infection, Headache, Myalgia |
Cactus Opuntia alone, standard treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Alborz University of Medical Science |
|
Iran |
2020-07-10 |
|
IR.ABZUMS.REC.1399.024, IRCT20200504047298N2 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
48 |
Zeinab Siami |
2020-06-19 |
| Patients Preferences About Rescheduling Colonoscopies Delayed Due to COVID-19: Cross-Sectional Study |
Colon tumor, Coronavirus disease 19 infection |
|
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Massachusetts General Hospital |
|
US |
2020-06-09 |
2021-04-30 |
2020P001579-1, NCT04432870 |
Phase Not Applicable |
Recruiting |
1 |
10 Months |
200 |
Karen Sepucha, PhD |
2020-06-18 |
| COVINOSE: Prospective diagnosis of Covid-19 infection using exhaled breath analysis by electronic nose |
Coronavirus disease 19 infection |
eNose alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Leiden University Medical Center |
|
Netherlands |
2020-04-17 |
2020-12-31 |
COVINOSE, NL8694 |
Phase Not Applicable |
Recruiting |
1 |
8 Months |
200 |
Geert Groeneveld |
2020-06-18 |
| Phase II trial of Rejuveinix for Covid-19 patients |
Coronavirus disease 19 infection |
Rejuveinix alone |
|
|
Reven LLC |
|
|
|
|
|
Phase 2 Clinical |
Planned |
0 |
|
|
|
2020-06-18 |
| Extracorporeal membrane oxygenation in patients with coronavirus disease 2019 |
Coronavirus disease 19 infection |
Extracorporeal membrane oxygenation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Amsterdam UMC |
|
Netherlands |
2020-03-01 |
2020-12-31 |
NL8706 |
Phase Not Applicable |
Recruiting |
1 |
10 Months |
200 |
Alexander Vlaar |
2020-06-18 |
| Quality of life in patients with suspected COVID-19 |
Coronavirus disease 19 infection |
|
|
|
Centre of expertise for chronic organ failure |
|
Netherlands |
2020-06-04 |
2020-12-01 |
NL8705 |
Phase Not Applicable |
Recruiting |
1 |
5 Months |
10000 |
Martijn Spruit |
2020-06-18 |
| A clinical study to assess PolyPEPI-SCoV-2 for the potential treatment of COVID-19 |
Coronavirus disease 19 infection |
PolyPEPI-SCoV-2 alone |
|
|
Treos Bio Ltd |
|
|
2020-10-31 |
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-06-23 |
| A clinical trial of mRNA vaccine (COVID-19), University of Tokyo/Daiichi-Sankyo for the potential treatment of COVID-19 infection |
Coronavirus disease 19 infection |
mRNA vaccine (COVID-19), University of Tokyo/Daiichi-Sankyo alone |
|
|
Daiichi Sankyo Co Ltd |
|
|
2021-03-31 |
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-06-17 |
| A study to assess the effect of PIKfyve inhibitors for the treatment of COVID-19 infection |
Coronavirus disease 19 infection |
PIKfyve inhibitors, Verge Genomics Inc alone |
|
|
Verge Genomics Inc |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-06-17 |
| PPE, COVID-19, HCW |
Coronavirus disease 19 infection |
personal protective equipment alone |
|
|
Universiti Malaysia Sarawak |
|
Malaysia |
2020-05-06 |
2020-09-30 |
54908, NMRR-20-878-54908 |
Phase Not Applicable |
Not yet recruiting |
35 |
4 Months |
|
Haniza Binti Sahdi, Nurul Fatiha binti Zuraidi |
2020-06-17 |
| Effects of patients' vision and emotions on covid-19 |
Coronavirus disease 19 infection, Depression, Vision disorder |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Universiti Kebangsaan Malaysia |
|
Malaysia |
2020-06-15 |
|
54953, NMRR-20-1123-54953 |
Phase Not Applicable |
Status not specified |
2 |
|
|
DR Bannu A/P Jayallan, Dr. Nor Fariza Ngah |
2020-06-17 |
| Personality traits, depression, work stress, frontliners, Covid-19 |
Acute stress disorder, Coronavirus disease 19 infection, Depression |
|
|
|
Tuanku Jaafar Hospital |
|
Malaysia |
2020-06-15 |
2020-12-31 |
54720, NMRR-20-875-54720 |
Phase Not Applicable |
Status not specified |
1 |
6 Months |
|
Hj. Binaw Samad |
2020-06-17 |
| Incidence of ADR |
Coronavirus disease 19 infection |
|
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Sungai Buloh |
|
Malaysia |
2020-06-09 |
|
55048, NMRR-20-1120-55048 |
Phase Not Applicable |
Status not specified |
1 |
|
|
|
2020-06-21 |
| ICRAD: ICRAD |
Coronavirus disease 19 infection, Rheumatoid arthritis |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sarawak General Hospital |
|
Malaysia |
2020-07-01 |
2021-01-01 |
55262, ICRAD, NMRR-20-1116-55262 |
Phase Not Applicable |
Not yet recruiting |
1 |
6 Months |
15 |
Dr Sharifah Aishah bt Wan Mohamad Akba |
2020-06-21 |
| Efficacy of a new COVID-19 treatment |
Coronavirus disease 19 infection |
artesunate alone, artesunate plus vitamin C |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Malagasy government |
An Oasis of Healing in Mesa, The LifeCo, University of Mauritius |
Madagascar |
2020-04-29 |
2020-09-29 |
PACTR202006899597082 |
Phase 2 Clinical |
Not yet recruiting |
1 |
5 Months |
60 |
MIORAMALALA Sedera, RAKOTO Rafanomezantsoa, RAKOTOARIVELO Rivonirina Andry, RAKOTOSAONA Riana, RAKOTOVAO Andriamiadana Luc, RAMANITRAHASIMBOLA David, RAPELANORO RABENJA Fahafahantsoa, RATSIMBASOA Claude Arsene |
2020-06-19 |
| Children with disability during the COVID-19 outbreak |
Coronavirus disease 19 infection |
|
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The University of Hong Kong |
|
Hong Kong |
2020-03-23 |
|
HKUCTR-2872, UW 20-178, protocol v1-20200306 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1356 |
Dr. Wan-yee Winnie Tso, HKUCTR Administrator |
2020-06-17 |
| RoKiCo: Prospective study to evaluate immunity to SARS-CoV2 in mothers with children in child-care facilities |
Coronavirus disease 19 infection |
biological sampling alone, polymerase chain reaction alone |
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Universitätsmedizin Rostock |
|
Germany |
2020-04-23 |
|
A 2020-0090, DRKS00021614, RoKiCo |
Phase Not Applicable |
Recruiting |
1 |
|
400 |
Dagmar Michel-Lubs, Emil C. Reisinger |
2020-06-17 |
| Effects of COVID-19 on lung function and gas exchange |
Coronavirus disease 19 infection, Interstitial lung disease, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Gesellschaft für Tauch- und Überdruckmedizin e.V, University Hospital, Bonn |
Klinik f. Lungenheilkunde und Beatmungsmedizin, Rhein-Maas Klinikum GmbH |
Germany |
2020-06-16 |
|
179/20, DRKS00022082 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
124 |
Ivanna Rühl, Lars Eichhorn |
2020-06-17 |
| PROFLO: Could prone positioning increase lung function for patients with severe COVID-19 infection? |
Coronavirus disease 19 infection, Hypoxia, Respiratory failure, Viral pneumonia |
high flow nasal cannula alone, noninvasive ventilation alone, prone positioning alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Uppsala County Council |
University Hospital of Uppsala |
Sweden |
2020-04-20 |
2021-06-25 |
1, ISRCTN54917435, PROFLO |
Phase Not Applicable |
Not yet recruiting |
2 |
14 Months |
240 |
Dr Rosen |
2020-06-17 |
| Influence of the Covid-19 pandemic on the patient mix in German emergency departments |
Coronavirus disease 19 infection |
|
|
|
BundeswehrKrankenhaus Ulm |
Klinikum WolfsburgZentrale Notfallaufnahme, Otto-von-Guericke-Universität Magdeburg, Universitätsklinik für Unfallchirurgie,AKTIN-Notaufnahmeregister, University Hospital Magdeburg, University Hospital, Aachen |
Germany |
2020-07-01 |
|
160/15, DRKS00022188 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
500000 |
Martin Kulla, Wiebke Schirrmeister |
2020-06-17 |
| Exploratory Study Of the Therapeutic Effect and Safety Of Rectal Ozone therapyin Patients Positive To SARS-CoV 2 With Mild To Moderate Symptoms (COVID-19) |
Coronavirus disease 19 infection |
conventional therapy alone, rectal ozone therapy alone, Variable regimens including Chloroquine , Heberferon , lopinavir + ritonavir , oseltamivir |
Exo-alpha sialidase inhibitor, HIV protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Center for Scientific Research, Cuba |
|
Cuba |
2020-06-08 |
2020-08-23 |
OZO-001, RPCEC00000320 |
Phase Not Applicable |
Not yet recruiting |
1 |
2 Months |
|
Suarez Iznaga, Zamora Rodriguez |
2020-06-19 |
| Efficacy and Safety of Sofosbuvir/Daclatasvir treatment in COVID-19: A randomized, controlled study |
Coronavirus disease 19 infection, Viral pneumonia |
Standard of care therapy alone, Daktavera plus Gratisovir |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
PHARCO CORPORATE |
|
Egypt |
2020-06-20 |
|
DRKS00022203, IRB0000687, U1111-1253-0458 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
90 |
Mostafa Yakoot |
2020-06-17 |
| The role of children in transmission of COVID19 pandemic: Two case series in Malaysia |
Coronavirus disease 19 infection |
|
|
|
Hospital Sungai Buloh |
|
Malaysia |
2020-06-01 |
2020-08-06 |
NMRR-20-1087-55233 |
Phase Not Applicable |
Status not specified |
1 |
2 Months |
|
Dr LIM SOK BEE |
2020-06-16 |
| Approachs and issues on Corona Disaster for EAP |
Coronavirus disease 19 infection |
Psychological education alone |
|
Healthy volunteers accepted |
ADVANTAGE Risk Management Co., Ltd. |
|
Japan |
2020-06-15 |
|
UMIN000040762 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Suzuki Junya |
2020-06-16 |
| Covid19HCW: Prevalence of seroconversion of COVID-19 among healthcare worker |
Coronavirus disease 19 infection |
RT-PCR test alone, seroconversion test kits alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
HOSPITAL QUEEN ELIZABETH II |
|
Malaysia |
2020-05-11 |
2020-07-31 |
Covid19HCW, NMRR-20-885-54906 |
Phase Not Applicable |
Not yet recruiting |
1 |
2 Months |
|
Dr Yen Chia How |
2020-06-18 |
| Children During the COVID-19 Outbreak |
Coronavirus disease 19 infection |
|
|
Preschool Children (2-5 yrs), Children (6-12 yrs) |
The University of Hong Kong |
Community Child Health Unit |
Hong Kong |
2020-03-23 |
|
HKUCTR-2871, UW 20-177, v1-20200305 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1356 |
Dr. Winnie Tso, HKUCTR Administrator |
2020-06-16 |
| Scientific guidance for risk-control and prevention of COVID-19 in professional soccer-players in Austria |
Coronavirus disease 19 infection |
RT-PCR alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Paracelsus Medical University |
|
Austria |
2020-05-18 |
|
415-EP/73/820-2020, DRKS00022166 |
Phase Not Applicable |
Recruiting |
1 |
|
250 |
Dagmar Schaffler |
2020-06-17 |
| A real-time national survey OF COVID-19 in hemoglobinopathy and rare inherited anemia patients |
Anemia, Coronavirus disease 19 infection, Sickle cell anemia, Thalassemia |
|
|
|
Queen Mary University of London |
|
UK |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
|
|
2020-06-16 |
| GI IN COVID-19 |
Coronavirus disease 19 infection |
|
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Queen Elizabeth |
|
Malaysia |
2020-05-18 |
2020-12-31 |
54764, NMRR-20-869-54764 |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
200 |
Dr Ho Yoke Fun |
2020-06-17 |
| Psychosocial experiences among quarantined healthcare workers |
Coronavirus disease 19 infection |
|
|
|
Universiti Malaysia Sarawak |
|
Malaysia |
2020-07-01 |
2020-09-30 |
54833, NMRR-20-1144-54833 |
Phase Not Applicable |
Not yet recruiting |
2 |
3 Months |
|
Prof. Chew Keng Sheng |
2020-06-17 |
| Studying tobacco use and quitting behavior due to the coronavirus lockdown in India |
Coronavirus disease 19 infection |
interviewer-administered telephone-based survey alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
HRIDAY, Public Health Foundation of India |
University of Edinburgh |
India |
2020-06-20 |
|
CTRI/2020/06/025850, HMSC proposal ref id: 2020-9500 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
800 |
Dr Monika Arora, Prof K Srinath Reddy |
2020-06-18 |
| RNB in UPUMS, Saifai |
Coronavirus disease 19 infection |
RNB (Raj Nirvan Bati) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Uttar Pradesh University of Medical Sciences |
|
India |
2020-06-14 |
|
CTRI/2020/06/025852 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
|
|
Dr Raj Kumar |
2020-06-17 |
| Mental Health of children during COVID-19 Pandemic |
Coronavirus disease 19 infection |
|
|
Children (6-12 yrs), Adolescents (13-17 yrs) |
ESI Post Graduate Institute of Medical Science and Research (PGIMSR) |
|
India |
2020-06-17 |
|
CTRI/2020/06/025853 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Jyoti Bagla, Mahima Rajan |
2020-06-17 |
| BCG for COVID-19: BCG Vaccination against COVID-19 |
Coronavirus disease 19 infection, Respiratory disease |
BCG vaccine alone |
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Indian Council of Medical Research |
|
India |
2020-06-25 |
|
BCG for COVID-19, CTRI/2020/06/025854, Version 3.2 |
Phase 4 Clinical |
Not yet recruiting |
6 |
|
1450 |
C Padmapriyadarsini, Dr Anant Mohan, Dr Asha Keetharam, Dr C Padmapriyadarsini, Dr R R Tiwari, Dr Rujuta Hadaye, Dr Toteja, Srikanth Tripathy |
2020-06-17 |
| DEFEAT-COVID: A clinical trial of leflunomide for the treatment of COVID-19 infection |
Coronavirus disease 19 infection |
leflunomide alone |
Dihydroorotate dehydrogenase inhibitor, Protein tyrosine kinase inhibitor |
|
Ashford and St. Peter's Hospitals NHS Trust |
LifeArc |
China, UK |
|
|
DEFEAT-COVID |
Phase Not Applicable |
Status not specified |
2 |
|
|
|
2020-06-20 |
| FLARE: A randomised, double-blind, 2×2 factorial placebo-controlled trial on the saftey and efficacy Favipiravir, lopinavir/ritonavir combination therapy in early antiviral therapy in COVID-19 infection |
Coronavirus disease 19 infection |
favipiravir plus lopinavir + ritonavir |
HIV protease inhibitor, RNA polymerase inhibitor |
|
University of London |
LifeArc |
UK |
|
|
FLARE |
Phase Not Applicable |
Status not specified |
1 |
|
|
|
2020-06-16 |
| Short-term Outcome of COVID-19 Surgical Patients: Case-series of a High-risk Area Community Hospital |
Coronavirus disease 19 infection |
surgical procedure alone |
|
|
Azienda Socio Sanitaria Territoriale di Lodi |
|
Italy |
2020-05-01 |
2020-05-30 |
COVID19NR1, NCT04430062 |
Phase Not Applicable |
Completed |
1 |
|
14 |
Michele Ballabio |
2020-06-18 |
| Clinical Analysis of Patients Hospitalized Due To COVID-19 |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
TNMC and BYL Nair Hospital |
|
India |
2020-06-21 |
|
CTRI/2020/06/025848 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1500 |
Minal Harde, Rakesh Bhadade |
2020-06-17 |
| Study to Evaluate the Safety and Efficacy of a Combination of Nitazoxanide and Hydroxychloroquine Versus Hydroxychloroquine Alone in COVID-19 Patients |
Coronavirus disease 19 infection |
hydroxychloroquine plus nitazoxanide |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Dr Reddy's Laboratories Ltd |
|
India |
2020-06-15 |
|
CTRI/2020/06/025849, CVD-19-CD-001 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
158 |
D Mallikarjuna Rao, Dr Apurva Agarwal |
2020-06-17 |
| Safety, Tolerability and Efficacy of Nangibotide in Mechanically Ventilated Patients With COVID-19 and Features of Systemic Inflammation |
Coronavirus disease 19 infection, Inflammatory disease, Respiratory failure |
nangibotide alone, standard of care alone |
TREM receptor 1 antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Inotrem SA |
|
France |
2020-06-30 |
2021-03-31 |
MOT-C-204, NCT04429334 |
Phase 2 Clinical |
Not yet recruiting |
1 |
9 Months |
60 |
Jean-Jacques Garaud, MD, Sébastien Gibot, MD |
2020-06-22 |
| Pre-Identified Homoeopathic Medicines In Asymptomatic Covid -19 Individuals Receiving Standard Treatment Protocol |
Coronavirus disease 19 infection |
Standard treatment alone, Variable regimens including Arsenicum album 30 , Bryonia 30 , Camphora 1M |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Central Council for Research in Homoeopathy |
|
India |
2020-06-22 |
|
CTRI/2020/06/025844 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
|
Dr Anil Khurana, Dr Varanasi Roja |
2020-06-19 |
| Registry for a Cardiovascular Patient Who COVID-19 Infection |
Acute coronary syndrome, Cardiac arrest, Coronavirus disease 19 infection, Heart arrhythmia, Myocarditis |
transthoracic echocardiography alone, ultrasound alone |
|
|
Hamad Medical Corp |
|
Qatar |
2020-06-02 |
2020-12-31 |
MRC-05-113, NCT04430374 |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
100 |
DR.Jassim Alsuwaidi Senior Consultant, Dr.Jassim Alsuwaidi Senior Consultant, MRC |
2020-06-16 |
| COVIpreg-UK: Studying the immune response and long-term morbidity of COVID-19 infection in pregnancy |
Coronavirus disease 19 infection |
|
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Queen Mary University of London |
February Foundation |
UK |
2020-05-07 |
2022-06-06 |
COVIpreg-UK, IRAS 283699, ISRCTN93266696 |
Phase Not Applicable |
Recruiting |
1 |
25 Months |
200 |
Dr Dodds, Dr Stamatina Iliodromiti |
2020-06-16 |
| A phase III trial of Inactivated vaccine (COVID-19), Sinovac Biotech for COVID-19 |
Coronavirus disease 19 infection |
CoronaVac alone |
|
|
Instituto Butantan, Sinovac Biotech Ltd |
|
Brazil |
|
|
|
Phase 3 Clinical |
Planned |
1 |
|
|
|
2020-06-18 |
| COVID-AIIMS: Low Dose Radiation Therapy for COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
low dose radiation therapy (70 cGy) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
All India Institute of Medical Sciences |
|
India |
2020-06-13 |
|
COVID-AIIMS, CTRI/2020/06/025862, LDRT-Covid-19 |
Phase 1 Clinical |
Recruiting |
1 |
|
10 |
Daya Nand Sharma |
2020-06-22 |
| Scientific evaluation of Immuno-modulatory effects of Ayush interventions on normal healthy and high-risk individuals in context with COVID-19 pandemic: An open-level study |
Coronavirus disease 19 infection |
Anu Taila put alone, Variable regimens including Amritadi Guggul , Ashwagandha Churna , Ashwagandha Vati , Ayush Raksha Kwath , Madhyashti Churna , Pippali Churna , Pippalimool Churna , Sanshmani Vaati , Shunthi Churna , kwath churna |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Department of Ayush Uttarakhand |
|
India |
2020-06-20 |
|
CTRI/2020/06/025861 |
Phase 3 Clinical |
Not yet recruiting |
9 |
|
500 |
Dr Alok Kumar Shukla, Dr Ashok Kumar Tiwari, Dr Avnish Kumar Upadhyay, Dr Deshraj Singh, Dr Jaideep Singh Bisht, Dr Krishna Kant Pandey, Dr Pankaj Kumar, Dr Rakesh Kumar Agarwal, Dr Sandeep Kumar, Dr Saroj Kumar Mishra, Dr Sunil Kumar Raturi, Dr Swastik Suresh |
2020-06-22 |
| EPIC 19: Observational study on suspected COVID 19 patients admitted to ICU |
Coronavirus disease 19 infection, Respiratory disease |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
St Johns Medical College |
|
India |
2020-06-22 |
|
CTRI/2020/06/025858, EPIC 19 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
500 |
Dr Amarja Ashok Havaldar |
2020-06-22 |
| CELMA: Safety and Efficacy of Mesenchymal Stem Cells in the Management of Severe COVID-19 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
Umbilical cord derived mesenchymal stem cells alone, Usual treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Trustem |
Fundación Universitaria de Ciencias de la Salud, Hospital Infantil Universitario de San Jose, Hospital de San Jose |
|
2020-07-31 |
2020-11-30 |
202001, CELMA, NCT04429763 |
Phase 2 Clinical |
Not yet recruiting |
0 |
4 Months |
30 |
Carlos Escobar-Soto, MD, PhD, Carolina Araque, MD, Esp, Guillermo Sánchez-Vanegas, MD, PhD, Jhon Jaime Sprockel Díaz, MD, Esp |
2020-06-16 |
| Safety of TY-027, a Treatment for COVID-19, in Humans |
Coronavirus disease 19 infection |
TY-027, Tychan alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Tychan Pte Ltd |
|
Singapore |
2020-06-09 |
2021-01-31 |
NCT04429529, SCT-001 |
Phase 1 Clinical |
Recruiting |
1 |
7 Months |
25 |
Anjali Baglody, MSc, Bo Hong Tay, Jenny Low, MBBS, Justin Ng, PhD, Shayne Lin |
2020-06-17 |
| LCECS: Development and Application of a Low-Cost Ear-Contactless Stethoscope Powered by Raspberry Pi and Python |
Coronavirus disease 19 infection |
Low-Cost Ear-Contactless Stethoscope alone |
|
Healthy volunteers accepted |
Shengjing Hospital of China Medical University |
|
China |
2020-06-12 |
2021-06-12 |
ChiCTR2000033830, LCECS |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
12 |
Chuan Yang |
2020-06-17 |
| A phase III clinical study of SARS-CoV-2 vaccine, Ad26.COV2-S for the treatment of COVID-19 |
Coronavirus disease 19 infection |
SARS-CoV-2 recombinant adenoviral vector vaccine (AdVac/PER.C6, COVID-19), Johnson & Johnson/Biomedical Advanced Research and Development Authority/Beth Israel Deaconess Medical Center alone |
|
|
Johnson & Johnson |
|
|
|
|
|
Phase 3 Clinical |
Planned |
0 |
|
|
|
2020-06-15 |
| COMETE-19: Covid-19 at the Regional Medical Center Metz-Thionville: a Descriptive Study |
Coronavirus disease 19 infection |
|
|
|
Centre Hospitalier Régional Metz-Thionville |
|
France |
2020-03-01 |
2021-06-30 |
2020-02OBS-CHRMT, COMETE-19, NCT04430322 |
Phase Not Applicable |
Recruiting |
1 |
16 Months |
330 |
Nadia OUAMARA, Rostane GACI, MD, Vincent DINOT |
2020-06-19 |
| Hydroxychloroquine Use in Hospitalized Patients With COVID-19: Impact on Progression to Severe or Critical Disease |
Coronavirus disease 19 infection |
hydroxychloroquine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
WellStar Health System |
|
US |
2020-05-07 |
2020-12-07 |
1604885, NCT04429867 |
Phase 4 Clinical |
No longer recruiting |
1 |
7 Months |
700 |
|
2020-06-18 |
| OpMiCoV: Explorative Study of the Association of Oropharyngeal Microbiota Profiles with SARS-CoV-2 Infection and COVID-19 disease |
Coronavirus disease 19 infection, Upper respiratory tract infection, Viral pneumonia |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Deutsches Krebsforschungszentrum |
|
Germany |
2020-04-02 |
|
DRKS00021424, OpMiCoV, S-194/2020, U1111-1253-4873 |
Phase Not Applicable |
No longer recruiting |
1 |
|
360 |
Christoph Stein-Thoeringer |
2020-06-17 |
| Epidemiological and Demographic Data From 150 Patients Diagnosed With Coronavirus Disease 2019 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sisli Etfal Hospital |
|
Turkey |
2020-05-15 |
2020-06-05 |
DM3334, NCT04430023 |
Phase Not Applicable |
Completed |
1 |
|
150 |
AYŞE SÜRHAN ÇINAR, ayse cinar |
2020-06-18 |
| Health Professional Exposure Assessment to Covid-19 (SERODRON) |
Coronavirus disease 19 infection |
RT-PCR test alone, blood sampling alone, serological test alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier de Tourcoing |
|
France |
2020-06-30 |
2020-12-31 |
NCT04429724, RIPH_2020_8 |
Phase Not Applicable |
Not yet recruiting |
3 |
6 Months |
6000 |
Pierre PATOZ, PharmD, SIVERY, Solange TREHOUX, PhD, VACHEE |
2020-06-17 |
| MAGIC: Impact of Smoking and Nicotine on the Risk of Being Infected With COVID-19 |
Coronavirus disease 19 infection, Nicotine dependence |
nicotine substitute therapy alone, serological test alone, smoking cessation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Central Hospital, Nancy, France |
|
France |
2020-07-01 |
2021-04-01 |
2020-A01681-38, MAGIC, NCT04429815 |
Phase Not Applicable |
Not yet recruiting |
1 |
9 Months |
489 |
Christian Rabaud |
2020-06-16 |
| A study to predict the disease progression in COVID-19 patients by analyzing blood samples of these patients from using high-throughput mass spectrometry platform |
Coronavirus disease 19 infection |
high-throughput mass spectrometry alone |
|
|
Charite Universitaetsmedizin Berlin |
The Francis Crick Institute |
UK |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
31 |
Prof. Dr. Markus Ralser |
2020-06-15 |
| A phase I clinical study to assess TP-508 in the treatment of patients with COVID-19 |
Coronavirus disease 19 infection |
rusalatide alone |
Factor IIa modulator |
|
Chrysalis BioTechnology Inc |
National Institute of Allergy and Infectious Diseases |
|
|
|
|
Phase 1 Clinical |
Planned |
0 |
|
|
|
2020-06-15 |
| Follow-up of COVID-19 Positive Patients |
Coronavirus disease 19 infection |
|
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Bangladesh Health Professions Institute |
|
Bangladesh |
2020-06-23 |
|
CTRI/2020/06/025857 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
200 |
K M Amran Hossain, Md. Obaidul Haque |
2020-06-19 |
| SARS-CoV2 IIF: Prospective Assay for SARS-CoV-2 Antibody Detection Indirectly by Immunofluorescence |
Coronavirus disease 19 infection |
SARS-CoV2 ELISA alone, immunofluorescence (SARS-CoV2 IIF ) alone, qPCR assay alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Szeged |
Biological Research Center of the Hungarian Academy of Sciences |
Hungary |
2020-05-30 |
2020-12-31 |
NCT04429620, SARS-COV-2-IIF-002, SARS-CoV2 IIF |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
100 |
Dávid Pintér, Pharm. D., Katalin Burián, MD |
2020-06-16 |
| A phase II clinical study to assess TP-508 in the treatment of patients with COVID-19 |
Coronavirus disease 19 infection |
rusalatide alone |
Factor IIa modulator |
|
Chrysalis BioTechnology Inc, National Institute of Allergy and Infectious Diseases |
|
|
|
|
|
Phase 2 Clinical |
Planned |
0 |
|
|
|
2020-06-15 |
| Evaluation of siddha regimen in the management of covid 19 |
Coronavirus disease 19 infection |
Variable regimens including Adathodai Manapagu , Kabasura kudineer , Thippili Rasayanam , Vasantha kusumakaram Mathirai |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Government Siddha Medical College |
|
India |
2020-06-25 |
|
CTRI/2020/06/025856 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
200 |
Dr N Anbu, Dr S M Chitra |
2020-06-22 |
| A retrospective, cohort, uncontrolled, exploratory study to evaluate the effects of treatment with interferon-alpha2b in the confirmed COVID-19 patients in Wuhan, China |
Coronavirus disease 19 infection |
interferon alpha-2b (COVID-19, inhaled), Altum Pharmaceuticals alone, arbidol plus interferon alpha-2b (COVID-19, inhaled), Altum Pharmaceuticals |
Interferon alpha ligand modulator |
|
Union Hospital Tongji Medical School Huazhong University Of Science & Technology |
|
China |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
77 |
|
2020-06-15 |
| Effect of AYUSH 64 in COVID 19 |
Coronavirus disease 19 infection |
AYUSH 64 alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Institute for Post Graduate Teaching and Research in Ayurveda |
|
India |
2020-06-15 |
|
CTRI/2020/06/025855 |
Phase 2 Clinical |
Not yet recruiting |
2 |
|
200 |
Dr Mandip Goyal, Dr Sagar M Bhinde, Dr Yagnik Chotala, Prof Anup Thakar |
2020-06-15 |
| SPIKE-1: A Randomized, Phase II/III trial to assess the use of camostat in reducing the clinical progression of COVID-19 by blocking SARS-CoV-2 Spike protein-initiated membrane fusion |
Coronavirus disease 19 infection |
camostat mesylate alone |
Serine protease inhibitor, Transmembrane serine protease 2 inhibitor, Trypsin inhibitor |
|
University of Edinburgh |
LifeArc |
UK |
|
|
SPIKE-1 |
Phase 2/Phase 3 Clinical |
Status not specified |
1 |
|
|
|
2020-06-16 |
| Serum protein marker in patients with novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Healthy volunteers accepted, Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Chongqing People'S Hospital |
|
China |
2020-02-01 |
2022-02-01 |
ChiCTR2000033872 |
Phase 0 Clinical |
No longer recruiting |
1 |
24 Months |
350 |
Ling Yan, Pu Liao |
2020-06-16 |
| Efficacy, Safety, Tolerability, and Biomarkers of MN-166 (Ibudilast) in Patients Hospitalized With COVID-19 and at Risk for ARDS |
Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia |
ibudilast (oral, neuropathic pain/opiate dependence/neurodegeneration/TBI/drug dependence/acute respiratory distress syndrome/COVID-19), MediciNova alone |
IL-6 receptor antagonist, Interleukin-1 beta ligand inhibitor, Macrophage migration inhibitory factor inhibitor, PDE 10 inhibitor, PDE 4 inhibitor, TLR-4 antagonist, TNF alpha ligand inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
MediciNova Inc, Yale School of Medicine |
|
US |
2020-07-31 |
2021-12-01 |
MN-166-COVID-19-201, NCT04429555 |
Phase 2 Clinical |
Not yet recruiting |
1 |
16 Months |
40 |
Dr. Geoffrey Chupp, Dr. Insoo Kang, Joanna Dojillo, MMsc, Kazuko Matsuda, MD PhD MPH, r. Maor Sauler |
2020-06-16 |
| A pilot study of baricitinib for treatment of bilateral COVID-19 pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
baricitinib alone |
Jak1 tyrosine kinase inhibitor, Jak2 tyrosine kinase inhibitor |
|
Eli Lilly & Co, Imperial College London |
|
Italy |
|
|
|
Phase 2 Clinical |
Status not specified |
1 |
|
4 |
|
2020-06-15 |
| The efficacy and safety of convalescent plasma therapy in novel coronavirus pneumonia (COVID-19): A medical records based retrospective, cohort study |
Coronavirus disease 19 infection, Viral pneumonia |
convalescent plasma therap alone, non-convalescent plasma therapy alone |
|
Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tongji Hospital, Huazhong University of Science and Technology |
|
China |
2020-06-12 |
2021-06-11 |
ChiCTR2000033798 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
150 |
Minghao Fang, Yi Bian |
2020-06-16 |
| Cerebral Compliance Impairment in COVID-19 |
Brain disease, Coronavirus disease 19 infection |
Brain4care (B4C) sensor alone, Transcranial Doppler alone |
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Sao Paulo |
|
Brazil |
2020-05-01 |
2020-07-31 |
31750820.1.0000.0068, NCT04429477 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
50 |
Gustavo Frigieri, PhD, Sergio Brasil, MD, Sergio Brasil, PhD |
2020-06-16 |
| DAWN-Plasma: Donated Antibodies Working Against nCoV |
Coronavirus disease 19 infection, Lower respiratory tract infection, Upper respiratory tract inflammation |
Convalescent plasma alone, Standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universitaire Ziekenhuizen Leuven |
Belgium Health Care Knowledge Centre |
Belgium |
2020-05-02 |
2021-11-02 |
DAWN-Plasma, NCT04429854, S63992 |
Phase 2 Clinical |
Recruiting |
14 |
18 Months |
483 |
Bernard Bouckaert, MD, Clotilde Visée, MD, Geert Meyfroidt, MD, PhD, Georgala Aspasia, MD, Jean Yombi, MD, Laurent Jadot, MD, Lucie Seyler, MD, Matthias Leys, MD, Michel Moutschen, MD, Nicolas Dauby, MD, Niels Van Regenmortel, MD, Timothy Devos, MD,PHD |
2020-06-22 |
| A phase II clinical study of self-amplifying RNA vaccine (im, COVID-19), Imperial College London for the potential prevention of SARS-CoV-2 infection (COVID-19) |
Coronavirus disease 19 infection |
self-amplifying RNA vaccine (im, COVID-19), Imperial College London alone |
COVID19 Spike glycoprotein inhibitor |
|
Imperial College London |
UK Government |
|
2020-06-30 |
|
|
Phase 2 Clinical |
Planned |
0 |
|
|
|
2020-06-15 |
| CGM-ISO: Remote Continues Glucose Monitoring During the COVID-19 Pandemic in Quarantined Hospitalized Patients |
Coronavirus disease 19 infection, Diabetes mellitus, Viral pneumonia |
CGM stratification alone, Dexcom G6 alone, Standard care with fingerprick glucose test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Nordsjaellands Hospital |
|
Denmark |
2020-05-25 |
2021-05-25 |
CGM-ISO, H-20025305, NCT04430608 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
72 |
Carina Klarskov, MD, Peter L. Kristensen, MD, ph.D |
2020-06-16 |
| HAD-Covid: Impact of Covid-19 Restrictive Measure on Anxiety, Depression and PTSD for Relatives of ICU Patients |
Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Clermont-Ferrand |
|
France |
2020-06-22 |
2022-01-22 |
2020 HAD-COVID, HAD-Covid, NCT04430049 |
Phase Not Applicable |
Not yet recruiting |
11 |
19 Months |
240 |
Alexandre Lautrette, MD, PhD, Anne Médard, MD, Arnaud Delahaye, MD, Christophe Leroy, MD, Edouard Soum, MD, Emmanuel Futier, MD,PhD, Jean-Etienne Bazin, MD, PhD, Lise Laclautre, Luc Jarrige, MD, Marie-Hélène Hausermann, MD, Nathanael Einsemann, Pierre-Marie Bertrand, MD, Ramin Ravan, MD, Russel Chabanne, MD, Sophie Cayot, MD, Thierry Gillard, MD |
2020-06-20 |
| COV003: A phase III study to investigate a vaccine against COVID-19 |
Coronavirus disease 19 infection |
AZD-1222 alone, AZD-1222 plus paracetamol |
COVID19 Spike glycoprotein modulator |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Federal University of Sao Paulo, University of Oxford |
The Lemann Foundation |
Brazil |
2020-05-01 |
2021-07-31 |
COV003, COV003, ISRCTN89951424 |
Phase 3 Clinical |
Recruiting |
1 |
15 Months |
2000 |
Dr Peter O'Reilly |
2020-06-16 |
| CATALYST: An adaptive, rapid, open-label, phase II, multi-arm, multi-stage clinical trial to evaluate the efficacy of IZN-101 and CT-P13 in the treatment of hospitalized patients with severe COVID-19 infection |
Coronavirus disease 19 infection |
infliximab biosimilar, Celltrion/Nippon Kayaku/Hospira/Orion/EGIS Gyogyszergyar alone, namilumab alone, standard of care alone |
GM-CSF ligand inhibitor, TNF alpha ligand inhibitor, TNF binding agent |
|
NIHR Birmingham Biomedical Research Centre, The University of Birmingham, University Hospital Birmingham NHS Foundation Trust |
NIHR Biomedical Research Centre, Oxford, United Kingdom Research & Innovation, University College London, University of Oxford |
UK, US |
|
|
CATALYST |
Phase 2 Clinical |
Recruiting |
2 |
|
160 |
Dr Ben Fisher, Dr Matt Rowland, Professor Duncan Richards |
2020-06-17 |
| A placebo-controlled trial to evaluate REGN-CoV2 for the prevention of COVID-19 in uninfected people with close exposure to a COVID-19 patient |
Coronavirus disease 19 infection |
REGN-CoV2 alone |
COVID19 Spike glycoprotein inhibitor |
|
Regeneron Pharmaceuticals Inc |
|
US |
2020-06-11 |
|
|
Phase Not Applicable |
Recruiting |
1 |
|
|
Dr. Suraj Saggar |
2020-06-19 |
| A placebo-controlled trial to evaluate REGN-CoV2 for the prevention of COVID-19 in uninfected people who are at high-risk of exposure |
Coronavirus disease 19 infection |
REGN-CoV2 alone |
COVID19 Spike glycoprotein inhibitor |
|
Regeneron Pharmaceuticals Inc |
|
US |
2020-06-11 |
|
|
Phase Not Applicable |
Recruiting |
1 |
|
|
Dr. Suraj Saggar |
2020-06-19 |
| ERNA: An intensive, longitudinal study on habit formation of hand washing behavior during the COVID-19 pandemic |
Coronavirus disease 19 infection |
hand washing alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Medical School Berlin |
Berlin Free University |
Germany |
2020-06-25 |
|
DRKS00022067, ERNA, MSB-2020/36 |
Phase Not Applicable |
Not yet recruiting |
5 |
|
134 |
Antonia Domke, Lena Fleig |
2020-06-15 |
| Ivermectin versus Placebo for the Treatment of Patients With Mild to Moderate COVID-19 |
Coronavirus disease 19 infection |
ivermectin alone |
Chloride channel modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sheba Medical Center |
|
Israel |
2020-05-12 |
2020-10-31 |
NCT04429711, SHEBA-20-7156-ES-CTIL |
Phase 2 Clinical |
Recruiting |
1 |
5 Months |
100 |
Asaf Biber, Dr., Eli Schwartz, M.D, Eli Schwartz, Prof., Prof. Eli Schwartz MD, DTMH |
2020-06-17 |
| A clincial study to assess immune response of QuadraMune in healthy subjects for the prevention of COVID-19 |
Coronavirus disease 19 infection |
QuadraMune alone |
|
Healthy volunteers accepted |
Therapeutics Solutions International Inc |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
8 |
Dr. James Veltmeyer |
2020-06-15 |
| Multicenter, adaptive, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of the drug ХС-221, 100 mg tablets, in patients with COVID-19 |
Coronavirus disease 19 infection |
XC-221 alone |
|
|
RSV Therapeutics LLC |
|
Russian Federation |
2020-06-09 |
2021-12-31 |
ХС221-03-02-2020 |
Phase 3 Clinical |
Status not specified |
7 |
18 Months |
150 |
|
2020-06-15 |
| Post-traumatic Stress Disease in Health Workers During COVID-19 Pandemia |
Coronavirus disease 19 infection, Post traumatic stress disorder |
Maslach Burnout Inventory (MBI) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
IRCCS AOU San Martino – IST |
|
Italy |
2020-03-01 |
2020-07-01 |
NCT04424771, PTSD-COVID-19 |
Phase Not Applicable |
Recruiting |
2 |
4 Months |
800 |
Eleonora Giuntoli, MD, Eleonora Guaitoli, Eleonora Guaitoli, MD, Fabio Barra, Fabio Barra, MD |
2020-06-15 |
| AKI C19 HKL: Acute kidney injury and renal replacement therapy: incidence and outcome in COVID-19 patients admitted to Hospital Kuala Lumpur |
Coronavirus disease 19 infection, Renal injury |
renal replacement therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Kuala Lumpur |
|
Malaysia |
2020-06-15 |
2021-12-31 |
55036, AKI C19 HKL, AKI C19 HKL, NMRR-20-1090-55036 |
Phase Not Applicable |
Not yet recruiting |
1 |
18 Months |
371 |
Dr NURUL ZAYNAH BINTI NORDIN |
2020-06-15 |
| BLAZE-1: A Study of LY-3819253 (LY-CoV555) in Participants With Early Mild-to-Moderate COVID-19 Illness |
Coronavirus disease 19 infection |
LY-CoV555 alone |
COVID19 Spike glycoprotein modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Eli Lilly & Co |
AbCellera Biologics Inc |
US |
2020-06-13 |
2020-09-15 |
17947, BLAZE-1, J2W-MC-PYAB, NCT04427501 |
Phase 2 Clinical |
Recruiting |
24 |
3 Months |
400 |
A Blomkalns, Adam Schwartz, Andra Blomkalns, B Heller, Carlos Malvestutto, DONALD PORETZ, David Pitrak, Erica Kaufman West, GERARD J CRINER, Gregory Huhn, Imad J Shawa, Jeffrey Glassberg, Katherine Belden, Kristin Highland, Mayur Ramesh, Michael L Dougan, Patrick Milligan, Peter Chen, Princy Kumar, Robert Gottlieb, V Stosor, Valentina Stosor, William A Fischer |
2020-06-24 |
| IDEA: Ivermectin, Aspirin, Dexametasone and Enoxaparin as Treatment of COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
Variable regimens including aspirin , dexamethasone , enoxaparin sodium , ivermectin |
Chloride channel modulator, Low molecular weight heparin |
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Eurnekian Public Hospital |
|
Argentina |
2020-05-01 |
2020-07-30 |
IDEA, IDEA, NCT04425863 |
Phase Not Applicable |
No longer recruiting |
1 |
2 Months |
100 |
Alfredo Secchi, M.D., Hector E Carvallo |
2020-06-24 |
| To Compare Videolaryngoscope Against Direct Laryngoscope for Intubation When Powered Air Purifying Respirator is Worn |
Anesthesia, Coronavirus disease 19 infection |
McGrath videolaryngoscope alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Singapore General Hospital Pte Ltd |
Duke-NUS Graduate Medical School |
Singapore |
2020-06-01 |
2020-12-31 |
2020/2329, NCT04424953 |
Phase Not Applicable |
Not yet recruiting |
1 |
7 Months |
60 |
Qing Yuan Goh, M.Med (Anes), Zihui Tan, M.Med (Anes) |
2020-06-16 |
| Efficacy of Convalescent Plasma Therapy in Patients With COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
Convalescent Plasma therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Institute of Liver and Biliary Sciences, India |
|
India |
2020-06-09 |
2021-05-30 |
ILBS-COVID-04, NCT04425915 |
Phase 3 Clinical |
Recruiting |
3 |
11 Months |
400 |
Dr Ankit Bhardwaj, Masters-CT, Dr Meenu Bajpai, MD, Dr Suresh Kumar, MD, Dr Vikas Dogra, MD |
2020-06-15 |
| Thorax Computed Tomography Severity Score and Outcome in COVID-19 Patients |
Coronavirus disease 19 infection, Viral pneumonia |
CT scan alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tepecik Training and Research Hospital |
|
Turkey |
2020-03-15 |
2020-07-15 |
2020/5-4, NCT04424849 |
Phase Not Applicable |
Recruiting |
1 |
4 Months |
40 |
Aykut Sarıtaş, Isıl K Guldogan, Işıl Köse Güldoğan, Kazim Rollas, Kazım Rollas, Naciye Sinem GEZER, Nimet Şenoğlu, Taner Çalışkan, Uğur Uzun, Yeliz Pekçevik, Çiler Zincircioğlu, İsa Sahar |
2020-06-15 |
| Cardiovascular Risk Factors and Severe COVID-19. A Nationwide, Registry-based, Case-control Study |
Cardiovascular disease, Coronavirus disease 19 infection, Hypertension, Non-insulin dependent diabetes, Obesity |
antidiabetic therapy alone, antihypertensive agent therapy alone, statin therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Karolinska Institutet |
|
Sweden |
2020-03-01 |
2022-12-31 |
4, NCT04426084 |
Phase Not Applicable |
No longer recruiting |
1 |
34 Months |
22784 |
Per Svensson |
2020-06-15 |
| AiM Covid Self Monitoring |
Coronavirus disease 19 infection |
AiM Covid App alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Aarogyam UK |
Mothers Touch Foundation, NMP Medical Research Institute, Warwick University |
India |
2020-04-12 |
2020-05-28 |
AU015, NCT04425044 |
Phase Not Applicable |
Completed |
2 |
1 Month |
1000 |
Vishwes Kulkarni |
2020-06-15 |
| Thymosin Alpha 1 to Prevent COVID-19 Infection in Elderly Renal Dialysis Patients |
Coronavirus disease 19 infection |
thymalfasin alone |
Thymosin receptor agonist |
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Inova Health Care Services |
DaVita Clinical Research, Nephrology Associates of Northern Virginia, Inc. |
US |
2020-06-30 |
2021-06-30 |
ACW-1221958-1, NCT04428008 |
Phase 2 Clinical |
Not yet recruiting |
1 |
12 Months |
240 |
William B Ershler, MD, William B. Ershler |
2020-06-18 |
| A Multicenter, Randomized, Double-blind, Placebo-controlled, Phase III Study Evaluating Favipiravir in Treatment of COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
favipiravir alone, supportive care alone |
RNA polymerase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Zhejiang Hisun Pharmaceutical Co Ltd |
Opera CRO |
Romania, Germany, China |
2020-06-30 |
2020-09-30 |
HS216C17(MRCT), NCT04425460 |
Phase 3 Clinical |
Not yet recruiting |
8 |
3 Months |
256 |
Dionisio Barattini, MD Europe, Opera CRO, Emanuel Dogaru, CPM, Opera CRO |
2020-06-16 |
| COVID-19 ORL: Smell and Taste Disorders in COVID-19 Patients |
Coronavirus disease 19 infection, Taste disorder |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Milano-Bicocca |
|
Italy |
2020-05-15 |
2020-09-30 |
COVID-19 ORL, COVID-19 ORL, NCT04427332 |
Phase Not Applicable |
Recruiting |
1 |
4 Months |
500 |
Dante Jean Garavello Werner Jean, Prof., Dante Jean Garavello Werner, Professor |
2020-06-16 |
| COVID_OFF: Detection of SARS-CoV-2 in Follicular Fluid and Cumulus-oocyte-complexes in COVID-19 Patients |
Coronavirus disease 19 infection |
Endometrial biopsy alone |
|
Female, Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
CRG UZ Brussel |
|
Belgium |
2020-06-15 |
2021-06-15 |
COVIDOFF001, COVID_OFF, NCT04425317 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
20 |
Elsie Nulens, Liese Boudry, Liese Boudry, MD |
2020-06-16 |
| Masq-Aute: Evaluation of ARFC Masks Equipped With CF5 Filter in the Care Unit to Allow a Wider Distribution of FFP2 Masks (Covid-19) |
Coronavirus disease 19 infection |
ARFC mask alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire de Saint Etienne |
|
France |
2020-04-29 |
2020-06-30 |
2020-A00817-32, 20CH073, Masq-Aute, NCT04427176 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
30 |
Andréa BUCHMULLER, MD, Bernard TARDY, MD PhD, Florence RANCON, CRA, Jean Luc PERROT, MD PhD, Jean-Luc PERROT, MD PhD |
2020-06-15 |
| TOLD: Trial of Open-Label Dipyridamole In Hospitalized Patients With COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure, Respiratory tract infection |
dipyridamole alone, standard care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
UConn Health |
|
US |
2020-05-03 |
2021-05-30 |
20-192-2.F, NCT04424901, TOLD |
Phase 2 Clinical |
Recruiting |
1 |
12 Months |
100 |
Bruce Liang, MD, Christopher Pickett, MD, Elizabeth Laska, RN, Eric Mortensen, MD, Jeffrey Aeschlimann, PharmD, Kevin Dieckhaus, MD, Mark Metersky, MD, Patti Keltonic, RN |
2020-06-15 |
| A phase Ia/Ib clinical trial of trans sodium crocetinate for the treatment of hospitalized COVID-19 patients displaying severe respiratory symptoms and low oxygen levels |
Coronavirus disease 19 infection |
trans sodium crocetinate alone |
|
|
ARENSIA Exploratory Medicine, Diffusion Pharmaceuticals LLC |
|
Romania |
2020-06-30 |
|
|
Phase 1 Clinical |
Planned |
1 |
|
|
Prof. Adrian Streinu-Cercel |
2020-06-12 |
| Vitamin A and COVID-19 |
Coronavirus disease 19 infection |
vitamin A alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Iran University of Medical Sciences |
|
Iran |
2020-05-21 |
|
IR.IUMS.REC.1399.204, IRCT20200405046951N1 |
Phase 3 Clinical |
Recruiting |
1 |
|
120 |
Azadeh Mottaghi |
2020-06-15 |
| Evaluation the effect of raltegravir and raltegravir/interferon beta combination on COVID-19 patients |
Coronavirus disease 19 infection |
Variable regimens including hydroxychloroquine , interferon beta , raltegravir |
HIV-1 integrase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Jahrom University of Medical |
|
Iran |
2020-06-19 |
|
IR.JUMS.REC.1399.028, IRCT20200412047042N1 |
Phase 3 Clinical |
Recruiting |
1 |
|
60 |
Dr Kavous Solhjoo, Dr Rahim Raoufi, ِDr Samaneh Zolghadri |
2020-06-19 |
| Assessment of Thermal Condition of Health Workers Who Use Personal Protective Equipment From Biological Hazards During Their Work With COVID-19 Patients |
Coronavirus disease 19 infection |
Personal protective equipment alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Federal State Budgetary Scientific Institution 'Izmerov Research Institute of Occupational Health' |
|
Russian Federation |
2020-06-03 |
2020-06-10 |
NCT04427267, PPE-02 |
Phase Not Applicable |
No longer recruiting |
1 |
|
6 |
Andrey Mikhailovich Geregey |
2020-06-17 |
| VENTED COVID: Low Dose Whole Lung Radiation Therapy for Patients With COVID-19 and Respiratory Compromise |
Coronavirus disease 19 infection, Hypoxia, Lung inflammation, Respiratory disease, Viral pneumonia |
ultralow dose-whole lung radiation therapy (80 cGy) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ohio State University Comprehensive Cancer Center |
|
US |
2020-06-11 |
2021-12-31 |
NCT04427566, VENTED, VENTED COVID |
Phase 2 Clinical |
Recruiting |
1 |
18 Months |
24 |
Arnab Chakravarti, Arnab Chakravarti, MD, Kimberly Mahler |
2020-06-24 |
| VExCO: Mechanical ventilator for use in patients with respiratory failure due to Covid-19 |
Coronavirus disease 19 infection, Respiratory failure |
ventilator alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Hospital Universitario Clementino Fraga Filho, Universidade Federal do Rio de Janeiro |
Foundation for Research Financial Support in the State of Rio de Janeiro (FAPERJ) |
Brazil |
2020-06-04 |
2020-06-11 |
4.063.224, CAAE: 31031920.2.0000.5257, RBR-2dxyx4, U1111-1252-8144, VExCO |
Phase Not Applicable |
Not yet recruiting |
1 |
|
5 |
Diamantino Ribeiro Salgado |
2020-06-16 |
| HFNC Treatment in COVID-19 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
high flow nasal cannula device alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sisli Hamidiye Etfal Training and Research Hospital |
|
Turkey |
2020-05-15 |
2020-06-05 |
5569, NCT04424836 |
Phase Not Applicable |
Recruiting |
1 |
|
40 |
ayse su cinar, mustafa altinay, mustafa altınay, nebia peker |
2020-06-17 |
| Therapeutic Vaccine Trial of COVID-19 for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection |
Coronavirus disease 19 infection |
Covax-19 alone |
Coronavirus spike glycoprotein inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Genecure LLC, Vaxine Pty Ltd |
|
|
2020-07-31 |
2021-12-31 |
GC004, NCT04428073 |
Phase 1 Clinical |
Not yet recruiting |
0 |
17 Months |
32 |
Frank Tung, Ph.D |
2020-06-19 |
| Identification of Genetic Factors Determining Disease Course in the New Type of Coronavirus Infection, COVID-19 |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Szeged |
|
Hungary |
2020-06-05 |
2021-07-31 |
COVID19_HUNGEN_001, NCT04426253 |
Phase Not Applicable |
No longer recruiting |
11 |
13 Months |
1000 |
Márta Széll, MD, Ph.D. |
2020-06-15 |
| Chloroquine + Losartan Compared to Chloroquine Alone for the Treatment of COVID-19 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
chloroquine phosphate plus losartan |
Angiotensin II AT-1 receptor antagonist, Angiotensin II receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Universitario Dr. Jose E. Gonzalez |
|
Mexico |
2020-03-10 |
2020-08-30 |
IF20-00003, NCT04428268 |
Phase 2 Clinical |
Recruiting |
1 |
5 Months |
20 |
Adrian Camacho Ortiz, MD, Adrian Camacho, PhD, Adrian Camacho-Ortiz, PhD, Eduardo Pérez Alba, MD, Juan Diego Lecona García, MD, Laura Marina Nuzzolo Shihadeh, MD |
2020-06-17 |
| Autologous Adipose-derived Stem Cells (AdMSCs) for COVID-19 |
Coronavirus disease 19 infection |
AdMSCs (osteoarthritis/rheumatoid arthritis), CelltexTherapeutics alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Celltex Therapeutics Corp |
|
US |
2020-06-20 |
2021-08-10 |
CTX0020-003, NCT04428801 |
Phase 2 Clinical |
Not yet recruiting |
1 |
13 Months |
200 |
Candy Eller, Derek W Guillory, MD. |
2020-06-17 |
| SERO-MARES: Prevalence and Risk Factors of SARS-CoV-2 Antibody Responses (COVID-19) |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital de Mataró |
|
Spain |
2020-06-08 |
2021-06-30 |
NCT04425759, SERO-MARES, SERO-MARES (56/20) |
Phase Not Applicable |
Recruiting |
2 |
12 Months |
2400 |
Pere Clavé, MD, Pere Clavé, MD, PhD |
2020-06-17 |
| IVERCAR: Usefulness of Topic Ivermectin and Carrageenan to Prevent Contagion of Covid 19 |
Coronavirus disease 19 infection |
personal protective equipment usage alone, Ivercass (ivermectin) plus iota carrageenan (Nasitral) |
|
Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Eurnekian Public Hospital |
|
Argentina |
2020-06-01 |
2020-08-30 |
IVERCAR, IVERCAR, NCT04425850 |
Phase Not Applicable |
No longer recruiting |
1 |
2 Months |
70 |
Hector E Carvallo |
2020-06-18 |
| BIG-C: Exploring Interventions for Glue Ear During Covid-19 |
Coronavirus disease 19 infection, Hearing loss, Otitis media |
Hear Glue Ear app (Cambridgeshire Community Services NHS Trust) alone, bone conduction headphone alone, microphone alone, telephone consultation alone, video consultation alone |
|
Preschool Children (2-5 yrs), Children (6-12 yrs) |
Cambridgeshire Community Services NHS Trust |
Cambridge University Hospitals NHS Foundation Trust |
UK |
2020-06-22 |
2021-06-01 |
262816, BIG-C, NCT04427631 |
Phase Not Applicable |
Not yet recruiting |
1 |
11 Months |
20 |
Alison Sansome, BM BCh MA MRCPCH, Dr. Tamsin Brown, Tamsin M Holland Brown, MBBS MRCPCH, alison Sansome, MBBS MRCPCH |
2020-06-15 |
| The efficacy of barely-based traditional remedy on COVID-19 |
Coronavirus disease 19 infection |
Variable regimens including atazanavir + ritonavir , barley-based remedy , chloroquine phosphate , hydroxychloroquine , lopinavir + ritonavir |
HIV protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shahid Beheshti University |
|
Iran |
2020-05-13 |
|
IR.SBMU.RETECH.REC.1399.074, IRCT20180923041093N6 |
Phase 3 Clinical |
No longer recruiting |
1 |
|
60 |
Mahmood Khodadoost, Roshanak Mokaberinejad |
2020-06-22 |
| COV-OB-ICU: Obesity and Mortality of Critically Ill Patients With COVID-19 |
Coronavirus disease 19 infection, Obesity, Respiratory failure, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Central Hospital, Nancy, France |
|
France |
2020-05-12 |
2020-05-26 |
2020PI082, COV-OB-ICU, NCT04425213 |
Phase Not Applicable |
Completed |
1 |
|
250 |
Olivier Ziegler, PU-PH |
2020-06-17 |
| Use of Remote Monitoring for COVID-19 Patient |
Coronavirus disease 19 infection |
LifeSignals Biosensor 1AX alone, Remote Patient Monitoring alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Montefiore Medical Center |
|
US |
2020-07-05 |
2021-06-01 |
NCT04425720, PENDING |
Phase Not Applicable |
Not yet recruiting |
1 |
10 Months |
300 |
Jonathan Leff, MD, Singh Nair, PhD |
2020-06-24 |
| Early Prone Position on Coronavirus Disease 2019 Pneumonia (Prone Position) |
Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia |
conventional oxygen therapy alone, prone position alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sisli Etfal Hospital |
|
Turkey |
2020-06-05 |
2020-06-15 |
NCT04427969, PP34 |
Phase Not Applicable |
Recruiting |
1 |
|
40 |
ayse surhan cinar, mustafa altinay, nebia peker |
2020-06-15 |
| MI-COVID: Predictive Factors COVID-19 Patients |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Milano-Bicocca |
|
Italy |
2020-03-01 |
2021-05-31 |
MI-COVID, MI-COVID, NCT04427345 |
Phase Not Applicable |
Recruiting |
1 |
15 Months |
1000 |
Paolo Bonfanti, Paolo Bonfanti, Professor |
2020-06-15 |
| Saliva/Nares as Source of Detection for SARS-CoV-2 at NIH |
Coronavirus disease 19 infection |
COVID-19 screening alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Institutes of Health Clinical Center |
|
US |
2020-06-29 |
2021-06-01 |
20-CC-0128, 200128, NCT04424446 |
Phase Not Applicable |
Recruiting |
1 |
11 Months |
5000 |
Karen M Frank, M.D., Rebecca A Nebel, Ph.D. |
2020-06-25 |
| COVID-19 Antibodies Among Healthcare Workers |
Coronavirus disease 19 infection |
COVID-19 IgG/IgM rapid test Cassette test (Healgen Scientific, Houston, Texas, USA) alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Universitario Dr. Jose E. Gonzalez |
|
Mexico |
2020-05-05 |
2020-06-01 |
IF20-00008, NCT04425889 |
Phase Not Applicable |
Completed |
1 |
|
156 |
Dr. Adrian Camacho-Ortiz |
2020-06-15 |
| Safety, Tolerability, and Efficacy of Anti-Spike (S) SARS-CoV-2 Monoclonal Antibodies for Hospitalized Adult Patients With COVID-19 |
Coronavirus disease 19 infection |
Face mask alone, High-intensity oxygen therapy alone, Low-flow oxygen therapy alone, Mechanical ventilation alone, Nasal cannula alone, REGN-CoV2 alone |
COVID19 Spike glycoprotein inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Regeneron Pharmaceuticals Inc |
|
US |
2020-06-12 |
2021-03-03 |
NCT04426695, R10933-10987-COV-2066 |
Phase 1/Phase 2 Clinical |
Recruiting |
1 |
8 Months |
1860 |
Clinical Trial Management, Clinical Trials Administrator, Dr. Suraj Saggar |
2020-06-17 |
| DOLCI: Darunavir/Cobicistat versus Lopinavir/Ritonavir in COVID-19 Pneumonia in Qatar |
Coronavirus disease 19 infection, Viral pneumonia |
darunavir + cobicistat (fixed dose, HIV infection), Janssen R&D/ Gilead alone, lopinavir + ritonavir alone |
Cytochrome P450 3 inhibitor, HIV protease inhibitor, HIV-1 protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hamad Medical Corp |
|
Qatar |
2020-03-01 |
2020-09-30 |
DOLCI, MRC-05-069, NCT04425382 |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
200 |
Dr. Eman Elmekaty, PharmD |
2020-06-15 |
| A phase I trial of SARS-CoV-2 virus-neutralizing mAbs (COVID-19), AstraZeneca/ VUMC for SARS-CoV-2 virus |
Coronavirus disease 19 infection |
SARS-CoV-2 virus-neutralizing mAbs (COVID-19), AstraZeneca/ VUMC alone |
|
|
AstraZeneca plc |
US Department of Defense, Vanderbilt University |
|
|
|
|
Phase 1 Clinical |
Planned |
0 |
|
|
|
2020-06-12 |
| INHIXACOV19: Enoxaparin in COVID-19 Moderate-to-Severe Hospitalized Patients |
Coronavirus disease 19 infection, Multiple organ failure, Respiratory failure, Septic shock, Thrombosis, Viral pneumonia |
enoxaparin sodium biosimilar, Techdow alone, standard thromboprophylaxis alone |
Low molecular weight heparin |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Policlinico S.Orsola-Malpighi, Universita di Bologna |
|
Italy |
2020-05-22 |
2020-10-30 |
2020-001308-40, INHIXACOV19, INHIXACOVID19, NCT04427098 |
Phase 2 Clinical |
Recruiting |
13 |
5 Months |
300 |
Andrea Romagnoli, MD, Antonella Castagna, MD, Aria Patacca, MD, Arturo Montineri, MD, Elena Giovanna Bignami, MD, Elvira Grandone, MD, Evelina Tacconelli, MD, Francesco Cristini, MD, Fulvia Mazzaferri, MD, Giovanni Di Perri, MD, Giulio De Stefano, MD, Maddalena Giannella, MD, Marco Baciarello, MD, Marco Mangiafico, MD, Massimo Salvetti, MD, Pierluigi Viale, MD, Raffaello Bellosta, MD, Renzo Rossini, MD, Salvatore Casari, Sophie Testa, MD, Stefano Bonorq, MD, Stefano Triscornia, BS |
2020-06-25 |
| COVID-19GAOM: RT-PCR SARS-CoV-2 at 1 Month of COVID-19 Infection in the Geriatric Population |
Coronavirus disease 19 infection |
RT-PCR SARS-CoV-2 test alone |
|
Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hopitaux Universitaires de Strasbourg |
|
France |
2020-05-07 |
2020-08-31 |
7838, COVID-19GAOM, NCT04427358 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
100 |
Maxence MEYER, MD, Saïd CHAYER, PhD, HDR |
2020-06-15 |
| STORM: The Natural History of Hospitalized COVID-19 Patients |
Coronavirus disease 19 infection, Inflammatory disease, Lung infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Milano-Bicocca |
|
Italy |
2020-02-23 |
2020-12-31 |
NCT04424992, STORM, STORM |
Phase Not Applicable |
No longer recruiting |
1 |
10 Months |
1433 |
|
2020-06-15 |
| Accelerated LFR for Bipolar Patients During the COVID-19 Pandemic |
Bipolar I disorder, Bipolar II disorder, Coronavirus disease 19 infection |
Accelerated low-frequency right-sided stimulation protocol alone, B70 Fluid-Cooled Coil alone, MagPro X100 Stimulator alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre for Addiction and Mental Health |
|
Canada |
2020-06-09 |
2022-12-31 |
071-2020, NCT04427137 |
Phase Not Applicable |
Recruiting |
1 |
30 Months |
50 |
Daniel Blumberger, MD, Dov Millstone, Hannah Taalman |
2020-06-24 |
| Utility of Lactoferrin as a Preventive Agent for Healthcare Workers Exposed to COVID-19 |
Coronavirus disease 19 infection |
lactoferrin alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Cairo University |
|
Egypt |
2020-07-31 |
2020-11-30 |
CUKA-002, NCT04427865 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
4 Months |
200 |
Gamal Esmat |
2020-06-18 |
| Core Warming of COVID-19 Patients |
Coronavirus disease 19 infection |
core warming alone, ensoETM device alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Washington University in St Louis |
|
US |
2020-06-30 |
2020-11-30 |
202005150, NCT04426344 |
Phase Not Applicable |
Not yet recruiting |
1 |
5 Months |
20 |
Anne Drewry, MD, Katie Dalton |
2020-06-15 |
| ILIAD-7-US-O: InterLeukin-7 to Improve Clinical Outcomes in Lymphopenic patients With COVID-19 Infection |
Coronavirus disease 19 infection, Lymphocytopenia, Respiratory failure |
CYT-107 alone |
IL-7 receptor agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Revimmune Inc |
Amarex Clinical Research, Memorial Sloan-Kettering Cancer Center |
US |
2020-06-22 |
2020-12-31 |
ILIAD-7 COVID US ONCO, ILIAD-7-US-O, NCT04426201 |
Phase 2 Clinical |
Not yet recruiting |
1 |
6 Months |
48 |
Frederique Berbille, MHSc, Marcel van den Brink, MD, PhD, Michel MORRE, DVM, Steve Pastores, MD |
2020-06-15 |
| CRI-CP: Effectiveness and Safety of Convalescent Plasma in Patients With High-risk COVID-19 |
Coronavirus disease 19 infection, Multiple organ failure, Respiratory disease, Respiratory failure, Septic shock, Viral pneumonia |
convalescent plasma alone, standard care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fundacion Santa Fe De Bogota |
|
Colombia |
2020-07-31 |
2021-02-28 |
CRI-CP, NCT04425837, PLASMA COVID-19 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
7 Months |
236 |
Guillermo E Quintero, Hematologist, Guillermo Enrique Quintero-Vega, José A De la Hoz, Epidemiologist, José De la Hoz, Epidemiologist |
2020-06-15 |
| Effect of Covid-19 Epidemic on Primary PCI in Patients With STEMI |
Coronavirus disease 19 infection, Myocardial infarction |
percutaneous coronary intervention (PCI) alone |
|
|
Beijing Friendship Hospital |
|
China |
2019-01-24 |
2021-07-24 |
BFH-COVID-19 AND PRIMARY PCI, NCT04427735 |
Phase Not Applicable |
Recruiting |
1 |
30 Months |
200 |
Hongwei Li, Hongwei Li, MD, Hongwei Li, doctor, Xuhe Gong |
2020-06-15 |
| Ivermectin In Treatment of COVID-19 Patients |
Coronavirus disease 19 infection |
ivermectin alone |
Chloride channel modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ministry of Health and Population |
|
Egypt |
2020-06-09 |
2020-09-01 |
14-2020/3, NCT04425707 |
Phase 2 Clinical |
Recruiting |
1 |
2 Months |
100 |
ehab ah kamal, MD, houssam ho masoud, MD, noha mo asem, MD |
2020-06-15 |
| COVEMUZ: SARS-COV-2 Seroprevalence and Seroconversion Among Employees of the Universitair Ziekenhuis Brussel During the 2020 COVID-19 Outbreak |
Coronavirus disease 19 infection |
blood sampling alone, questionnaire alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universitair Ziekenhuis Brussel |
|
Belgium |
2020-05-12 |
2021-05-12 |
COVEMUZ, COVEMUZ, NCT04426292 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
3500 |
Laurien De Greef, Nurse, Sabine Allard, MD |
2020-06-15 |
| HOT-COVID: Handling Oxygenation Targets in COVID-19 |
Coronavirus disease 19 infection, Hypoxia, Respiratory failure |
oxygen alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Aalborg Universitetshospital |
Copenhagen Trial Unit, Rigshospitalet, Denmark |
Denmark |
2020-08-01 |
2024-03-01 |
2017-000632-34, AAUH-ICU-03, HOT-COVID, NCT04425031 |
Phase 4 Clinical |
Not yet recruiting |
1 |
43 Months |
780 |
Bodil Steen Rasmussen, MD, PhD, Olav Lilleholt Schjørring, MD, PhD, Thomas Lass Klitgaard, MD |
2020-06-17 |
| CORONEVRAXE: Study of the Sars-Cov2 Neuroinvasiveness - COVID-19 |
Coronavirus disease 19 infection, Neurological disease |
cerebrospinal fluid sampling alone, meningeal and brain parenchyma biopsies alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fondation Ophtalmologique Adolf De Rothschild |
|
France |
2020-06-30 |
2022-06-30 |
CORONEVRAXE, NCT04427254, PBN_2020_16 |
Phase Not Applicable |
Not yet recruiting |
1 |
24 Months |
500 |
Amélie YAVCHITZ, MD, Pierre BOURDILLON, MD |
2020-06-15 |
| PLACO-COVID: Standard or Convalescent Plasma in Patients With Recent Onset of COVID-19 Respiratory Failure |
Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure |
COVID-19 convalescent plasma alone, standard plasma alone, standard therapy protocol alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Azienda Ospedaliera Citta della Salute e della Scienza di Torino |
|
Italy |
2020-06-15 |
2021-12-15 |
CS3/33, NCT04428021, PLACO-COVID |
Phase 2 Clinical |
Not yet recruiting |
1 |
18 Months |
180 |
Paola Maria Manzini |
2020-06-15 |
| CORhum: Morbimortality of Covid-19 in Patients With Chronic Inflammatory Rheumatism Treated With Immunosuppressants |
Coronavirus disease 19 infection, Rheumatoid arthritis, Spondylarthritis, Systemic lupus erythematosus |
questionnaire assesment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Regional Universitaire de Lille |
|
France |
2020-08-31 |
2020-12-31 |
2020-A01650-39, CORhum, EQ2020_04, NCT04426279 |
Phase Not Applicable |
Not yet recruiting |
1 |
4 Months |
1500 |
Jean-Guillaume Letarouilly, MD |
2020-06-15 |
| MK-5475 in Participants With Hypoxemia Due to COVID-19 Pneumonia |
Coronavirus disease 19 infection, Hypoxia, Viral pneumonia |
MK-5475 alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Merck Sharp & Dohme Corp |
|
|
2020-07-07 |
2020-11-10 |
2020-002062-14, 5475-009, MK-5475-009, NCT04425733 |
Phase 1 Clinical |
Not yet recruiting |
0 |
4 Months |
64 |
Medical Director |
2020-06-15 |
| CRISIS: Safety and Anti-coronavirus Response of Suppression of Host Nucleotide Synthesis in Patients With COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
brequinar alone, standard of care alone |
Dehydrogenase inhibitor, Dihydroorotate dehydrogenase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Clear Creek Bio, Inc |
|
US |
2020-06-12 |
2020-10-31 |
CCB-CRISIS-01, CRISIS, NCT04425252 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
3 |
4 Months |
24 |
Barbara L Powers, Ph.D, Gerard J Criner, MD, James S Pope, MD, Karel Calero, MD, Samuel Pope, MD |
2020-06-17 |
| CARDS: Cancer: Rapid Diagnostics and Immune Assessment for SARS-CoV-2 (COVID-19) |
Advanced solid tumor, Coronavirus disease 19 infection, Lymphoma |
antigen lateral flow assay alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The Royal Marsden NHS Trust |
Mologic Ltd, NIHR Biomedical Research Centre, Oxford, St Georges University of London, The Royal Marsden Cancer Charity |
UK |
2020-05-26 |
2021-04-30 |
20/NE/0139, CARDS, CCR 5287, NCT04427280 |
Phase Not Applicable |
Recruiting |
1 |
11 Months |
60 |
David Lau, MBBS FRACP, Shannon Kidd, Sheela Rao, MD FRCP, Sue Cromarty |
2020-06-19 |
| A multicenter, randomized, double-blind, parallel-arm, placebo-controlled, phase II/III clinical study to assess opaganib in patients hospitalized with severe SARS-CoV-2 infection and pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
opaganib alone, standard-of-care alone |
Dihydroceramide delta 4 desaturase inhibitor, Sphingosine kinase 2 inhibitor |
|
RedHill Biopharma Ltd |
|
Russian Federation, UK, Italy, Europe |
|
|
|
Phase 2/Phase 3 Clinical |
Planned |
3 |
|
270 |
|
2020-06-22 |
| A Phase II Trial of Infliximab in Coronavirus Disease 2019 (COVID-19) |
Coronavirus disease 19 infection, Viral pneumonia |
Variable regimens including Tylenol , diphenhydramine , infliximab , infliximab biosimilar, Samsung Bioepis/ Merck & Co , prednisone |
TNF alpha ligand inhibitor, TNF binding agent |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tufts Medical Center |
National Institutes of Health |
US |
2020-06-01 |
2020-12-31 |
NCT04425538, STUDY00000564 |
Phase 2 Clinical |
Recruiting |
1 |
7 Months |
17 |
Christian Lawlor, Jaime Chisholm, Paul Mathew, MD |
2020-06-15 |
| Safety, Tolerability, and Efficacy of Anti-Spike (S) SARS-CoV-2 Monoclonal Antibodies for the Treatment of Ambulatory Adult Patients With COVID-19 |
Coronavirus disease 19 infection |
REGN-CoV2 alone |
COVID19 Spike glycoprotein inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Regeneron Pharmaceuticals Inc |
|
US |
2020-06-09 |
2020-11-21 |
NCT04425629, R10933-10987-COV-2067 |
Phase 1/Phase 2 Clinical |
Recruiting |
1 |
5 Months |
1054 |
Clinical Trial Management, Clinical Trials Administrator |
2020-06-17 |
| A randomized, placebo-controlled, phase III clinical trial to assess losmapimod the treatment of patients with COVID-19 |
Coronavirus disease 19 infection |
losmapimod alone |
Double homeobox protein 4 inhibitor, p38 MAP kinase alpha inhibitor, p38 MAP kinase beta inhibitor, p38 MAP kinase inhibitor |
|
Fulcrum Therapeutics Inc |
|
US |
|
|
|
Phase 3 Clinical |
Planned |
1 |
|
|
|
2020-06-12 |
| A study to evaluate the clinical characteristics and epidemiological trend of COVID-19 infected children with or without GI symptoms |
Coronavirus disease 19 infection |
|
|
|
The University of Hong Kong |
Wuhan medical care center for women and children |
Hong Kong |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
244 |
Dr Kenneth Wong Kak-yuen |
2020-06-12 |
| MRCS: 'Minority and Rural Health Coronavirus Study (MRCS)' to evaluate the impact of COVID-19 on racial minorities and underserved communities across the country |
Coronavirus disease 19 infection |
|
|
|
Centene Corp, National Minority Quality Forum (NMQF), Quest Diagnostics Inc |
|
US |
2020-06-30 |
|
MRCS |
Phase Not Applicable |
Not yet recruiting |
1 |
|
5000 |
Alan Morgan, Elizabeth Ofili, Gary Puckrein, Gloria Wilder, Latrice Landry, Richard Beswick, Salaheddin Mahmud, Suja M. Mathew, Thomas LaVeist, Vin Gupta, William A. Meyer |
2020-06-12 |
| DOD: A Multicenter, Randomized-Controlled trial to Assess the Safety and Efficacy of Seraph 100 Microbind Affinity Blood Filter (Seraph 100) in the treatment of critically-ill COVID-19 patients |
Coronavirus disease 19 infection |
Seraph 100 Microbind Affinity Blood Filter alone |
|
|
ExThera Medical LLC |
US Department of Defense |
Europe, US |
|
|
DOD |
Phase Not Applicable |
Planned |
2 |
|
|
|
2020-06-11 |
| An multi-national multicenter clinical trial of YS-SC2-010 for the treatment of Coronavirus disease 19 infection |
Coronavirus disease 19 infection |
YS-SC2-010 alone |
|
|
Yisheng Biopharma Co Ltd |
|
South East Asia, China, Europe, US |
|
|
|
Phase Not Applicable |
Planned |
2 |
|
|
|
2020-06-11 |
| A clinical study to evaluate the safety and tolerability of TY-027 for the treatment of COVID-19 |
Coronavirus disease 19 infection |
TY-027, Tychan alone |
|
Healthy volunteers accepted |
Tychan Pte Ltd |
|
|
|
|
|
Phase 1 Clinical |
Recruiting |
0 |
|
23 |
|
2020-06-15 |
| A clinical proof-of-concept study to assess SARS-CoV-2-specific virus-neutralizing antibodies for the potential treatment of COVID-19 |
Coronavirus disease 19 infection |
SARS-CoV-2-neutralizing monoclonal antibodies (COVID-19), Memo Therapeutics alone |
|
|
Memo Therapeutics AG |
|
|
2020-12-31 |
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-06-11 |
| An observation study to assess the effect of favipiravir in hospitalized patients with COVID-19 |
Coronavirus disease 19 infection |
favipiravir alone |
RNA polymerase inhibitor |
|
Fujita Health University |
|
Japan |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
|
|
2020-06-11 |
| A clinical study of anti-SARS-CoV-2 spike glycoprrotein monoclonal antibody (COVID-19), Celletrion for the treatment of COVID-19 |
Coronavirus disease 19 infection |
CT-P59 alone |
COVID19 Spike glycoprotein inhibitor, Moesin modulator |
|
Celltrion Healthcare Co Ltd |
|
|
2020-07-31 |
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-06-15 |
| PI-Covid-19: Primary Prevention of Infection by COVID-19 in Health Providers |
Coronavirus disease 19 infection |
immunostimulant therapy alone, Variable regimens including allicin , eugenol , quercetin |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Unidad de Investigación Genética Molecular |
Universidad de Antioquia |
Colombia |
2020-07-31 |
2020-09-30 |
NCT04420260, PI-Covid-19, UNIGEM PT-IC-02 |
Phase 2 Clinical |
Not yet recruiting |
1 |
2 Months |
300 |
Beatriz H Aristizabal, PhD, Clara I Aristizabal, CEO, Clara Ines Aristizaba |
2020-06-11 |
| A trial to assess LVRNA-009 for COVID-19 vaccine |
Coronavirus disease 19 infection |
LVRNA-009 alone |
COVID19 Spike glycoprotein modulator |
|
Zhuhai Lifanda Biotechnology Co Ltd |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
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|
2020-06-11 |
| COVID-19-Related Health and Infection Control Practices Among Dentists |
Coronavirus disease 19 infection |
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Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
American Dental Association Foundation |
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US |
2020-06-08 |
2021-06-08 |
20-08, NCT04423770 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
4000 |
Cameron G Estrich, MPH, PhD, Marcelo Araujo, DDS, MS, PhD |
2020-06-12 |