Last updated: Aug 15, 2020 - 02:00 BST
| FREEDOM COVID: FREEDOM COVID-19 Anticoagulation Strategy |
Coronavirus disease 19 infection |
apixaban alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Mount Sinai Medical Center |
|
US |
2020-09-30 |
2021-06-30 |
FREEDOM COVID, GCO 20-2115, NCT04512079 |
Phase 4 Clinical |
Not yet recruiting |
0 |
9 Months |
3600 |
Anu Lala, MD, Debra Fitzpatrick, MS, Valentin Fuster, MD, PhD, Valentin Fuster, MD,PhD |
2020-08-14 |
| Scaling Mental Healthcare in COVID-19 With Voice Biomarkers |
Anxiety disorder, Coronavirus disease 19 infection, Depression |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kintsugi Mindful Wellness Inc |
|
|
2020-09-01 |
2021-06-30 |
COV-1, NCT04510519 |
Phase Not Applicable |
Not yet recruiting |
0 |
10 Months |
50 |
|
2020-08-14 |
| COVID-19 in Immunosuppressed Children |
Coronavirus disease 19 infection, Kidney transplantation, Liver transplantation |
|
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
D'Or Institute for Research and Education |
Hospital Estadual da Criança, Hospital Federal de Bonsucesso, Rio de Janeiro State Research Supporting Foundation |
Brazil |
2020-06-30 |
2021-04-30 |
062-2020, NCT04511429 |
Phase Not Applicable |
Recruiting |
0 |
10 Months |
200 |
Antonio José L A da Cunha, MD, PhD, Arnaldo Prata-Barbosa, MD, PhD, Jaqueline LS Gouveia, MD, Thais L Cleto-Yamane, Thais L Cleto-Yamane, MD, MSc |
2020-08-14 |
| MentCovRMD: Mental Health Consequences of COVID19 Infection in the French RMD Cohort |
Autoimmune disease, Autoinflammatory disease, Coronavirus disease 19 infection, Inflammatory disease, Musculoskeletal disease |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Regional Universitaire de Lille |
FAI²R (Auto-immune and auto-inflammatory rare diseases French network) |
France |
2020-09-30 |
2021-02-28 |
2020-A02058-31, 2020_75, MentCovRMD, NCT04510467 |
Phase Not Applicable |
Not yet recruiting |
0 |
5 Months |
1313 |
Eric Hachulla, MD,PhD |
2020-08-14 |
| A clinical study to assess the effects of Meditation (Mindful Happiness) as an additional therapy in asymptomatic and mildly symptomatic covid-19 confirmed cases |
Coronavirus disease 19 infection |
Meditation (Mindful Happiness) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Sonalika Social development Society |
|
India |
2020-08-11 |
|
CTRI/2020/08/027032, TG/PRO/CLI/034 Version 1.0 dated 10 July 2020 |
Phase Not Applicable |
Not yet recruiting |
0 |
|
40 |
Dr Bhageerathi Byrapura Lakshmegowda, Dr Vishwas Vijayadev, Meena Dalal |
2020-08-14 |
| COLHEART-19: Colchicine versus Current Standard of Care in Hospitalized Patients With COVID-19 and Cardiac Injury |
Coronavirus disease 19 infection, Heart injury |
Covid-19 standard of care alone, colchicine (oral, gout/familial Mediterranean fever), Takeda alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Miami Cardiac and Vascular Institute |
University of California Los Angeles |
US |
2020-09-01 |
2022-01-01 |
152247, COLHEART-19, NCT04510038 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
0 |
16 Months |
75 |
Raul E Herrera, MD, Sandra Chaparro, MD |
2020-08-14 |
| AI-COV-19: Artificial Intelligence-assisted Diagnosis and Prognostication in COVID-19 Using Electrocardiograms |
Coronavirus disease 19 infection |
CT scans alone, Chest x-ray imaging alone, ECGs alone, RTPCR assay alone, heart tracings alone, machine learning algorithms alone, train artificial intelligence alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Imperial College London |
Chelsea and Westminster Hospital, Imperial College Healthcare NHS trust, London North West Healthcare NHS Trust |
UK |
2020-05-26 |
2022-05-01 |
20HH5967, AI-COV-19, NCT04510441 |
Phase Not Applicable |
Recruiting |
0 |
23 Months |
2000 |
Abtehale Al-Hussaini, MRCP PhD, Emmanuel Ako, MRCP PhD, Fu Siong Ng, Jaymin Shah, MRCP PhD, Kiran Patel |
2020-08-14 |
| A clinical trial of CYC-065 and seliciclib as potential early treatments for the inflammatory response observed in patients with COVID-19 disease |
Coronavirus disease 19 infection, Inflammatory disease |
fadraciclib plus seliciclib |
Cyclin E inhibitor, Cyclin-dependent kinase-2 inhibitor, Cyclin-dependent kinase-5 inhibitor, Cyclin-dependent kinase-7 inhibitor, Cyclin-dependent kinase-9 inhibitor, MCL1 gene inhibitor |
|
Cyclacel Pharmaceuticals Inc |
University of Edinburgh |
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-08-14 |
| CanCovDia: Canakinumab in Patients With COVID-19 and Type 2 Diabetes |
Coronavirus disease 19 infection, Non-insulin dependent diabetes |
canakinumab alone |
Immunoglobulin G1 agonist, Interleukin-1 beta ligand inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Basel |
Novartis AG, Swiss National Science Foundation |
Switzerland |
2020-09-30 |
2023-09-30 |
2020-02008, ME20DONATH2, CanCovDia, NCT04510493 |
Phase 3 Clinical |
Not yet recruiting |
0 |
36 Months |
112 |
Alain Golay, MD, Prof., Beat Müller, MD, Prof., Christoph Henzen, MD, Prof., Christoph Stettler, MD, Prof., Felix Beuschlein, MD, Prof., François Jornayvaz, MD, PD, Jonathan Mudry, MD, Lukas Burget, MD, Manuel Battegay, MD, Prof., Marc Donath, MD, Prof., Markus Laimer, MD, Prof., Matthias Hepprich, MD, Michael Brändle, MD, Prof., Nelly Pittteloud, MD, Prof., Patrick Hunziker, MD, Prof., Peter Kopp, MD, Prof., Philipp Schütz, MD, Prof., Roger Lehmann, MD, Prof., Stefan Bilz, MD, PD, Stefan Fischli, MD |
2020-08-14 |
| FAMICOV: Epidemiological Study of the Spread of SARS-CoV-2 in the Household of a Person Who Has Had a COVID Disease |
Coronavirus disease 19 infection |
COVID-19 IgG / IgM rapid test (manufactured by the firm AAZ) alone, COVID-PRESTO alone |
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre de Recherches et d'Etude sur la Pathologie Tropicale et le Sida |
|
France |
2020-07-12 |
2020-11-30 |
CREPATS 012, FAMICOV, NCT04511949 |
Phase Not Applicable |
Recruiting |
0 |
4 Months |
500 |
Christine Katlama, Yasmine Dudoit |
2020-08-14 |
| A phase II to assess safety, tolerability and pharmacokinetics (PK) of PLN-74809, as well as exploratory clinical outcome measures in patients hospitalized with severe and critical COVID-19 associated with acute respiratory distress syndrome (ARDS) |
Coronavirus disease 19 infection, Respiratory distress syndrome |
PLN-74809 alone |
Integrin alpha-V/beta-1 antagonist, Integrin alpha-V/beta-6 antagonist |
|
Pliant Therapeutics Inc |
|
US |
2020-12-31 |
|
|
Phase 2 Clinical |
Planned |
0 |
|
|
|
2020-08-14 |
| Effect of Prolectin-M, a Food Supplement, on SarsCoV2 Viral Copy Numbers: A Proof of Concept, Randomized, Open-Label, Controlled Trial (Prolectin) |
Coronavirus disease 19 infection |
Prolectin (Pharmalectin - M) alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Composite Interceptive Med-Science Laboratories Pvt Ltd |
Pharmalectin Inc |
India |
2020-09-01 |
2020-09-30 |
CIMED - 002- 2020, NCT04512027 |
Phase Not Applicable |
Not yet recruiting |
0 |
1 Month |
10 |
|
2020-08-14 |
| STAR-COVID: Telmisartan in Respiratory Failure Due to COVID-19 |
Coronavirus disease 19 infection, Hypoxia, Respiratory failure, Tachypnea |
standard care alone, telmisartan alone |
Angiotensin II receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Regional de Alta Especialidad de Zumpango |
Instituto Politecnico Nacional |
Mexico |
2020-08-31 |
2021-04-30 |
CI/HRAEZ2020/05, NCT04510662, STAR-COVID |
Phase 2 Clinical |
Recruiting |
0 |
8 Months |
60 |
Abraham Edgar Gracia-Ramos, MD MSc, Maria Jose Pecero Hidalgo, MD, Maria Jose Pecero-Hidalgo, MD |
2020-08-14 |
| PSY-CO-ICU: Psychological Impact of COVID-19 Outbreak on Caregivers |
Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire de Nimes |
|
France |
2020-09-30 |
2021-09-30 |
LOCAL/2020/JYL-03, NCT04511780, PSY-CO-ICU |
Phase Not Applicable |
Not yet recruiting |
0 |
12 Months |
5000 |
Alexandre OUATTARA, Antoine ROQUILLY, Audrey DE JONG, Aurélie GOUEL, Belaid BOUHEMAD, Benoit PLAUD, Benoit VEBER, Bernard ALLAOUCHICHE, Bernard CHOLLEY, Bérangère VIVET, Claire DAHYOT FIZELIER, Claude ECOFFEY, Corentin LACROIX, Emmanuel FUTIER, Emmanuel SAMAIN, Eric PIKNIS, Etienne GAYAT, Francis REMERAND, Frédéric AUBRUN, Gael PITON, Guillaume BESCH, Guylaine LABRO, Gérald CHANQUES, Géralde CHANQUES, Gérard AUDIBERT, Hervé DUPONT, ICHAI Carole, Jacques ALBANESE, Jacques DURANTEAU, Jean Etienne BAZIN, Jean François PAYEN, Jean Luc FELLAHI, Jean Michel CONSTANTIN, Jean Yves LEFRANT, Julien POTTECHER, Jérôme MOREL, Karim ASEHNOUNE, Karim LAKHAL, Lionel VELLY, Mar Olivier FISCHER, Marc LAFFON, Marc LEONE, Marie reine LOSSER, Matthieu BIAIS, Matthieu LE DORZE, Nathalie NATHAN-DENIZOT, Nathan FERRAND, Nicolas BRUDER, Nicolas MONGARDON, Olivier BARBOT, Olivier FOURCADE, Olivier HUET, Olivier JOANNES BOYAU, Olivier LANGERON, Philippe GUERCI, Philippe MONTRAVERS, Philippe SEGUIN, Pierre François PERRIGAULT, Rémy BELLIER, Samir JABER, Sigismond LASOCKI, Sébastien PILI-FLOURY, Thomas KERFORNE, Thomas RIMMELE, Xavier CAPDEVILA, Yazine MAHJOUB, marc GARNIER |
2020-08-14 |
| C-MORE: Capturing Multi-organ Effects of COVID-19 |
Brain injury, Coronavirus disease 19 infection, Heart injury, Liver injury, Lung injury, Renal injury, Respiratory distress syndrome, Viral pneumonia |
6 min walk test alone, blood test alone, cardiopulmonary exercise test alone, computed tomography alone, magnetic resonance imaging alone, spirometry alone, transthoracic echocardiography alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Oxford |
|
UK |
2020-05-13 |
2023-05-01 |
282608, C-MORE, NCT04510025 |
Phase Not Applicable |
Recruiting |
0 |
35 Months |
616 |
Betty Raman, MBBS, DPhil, FRAC, Betty Raman, MBBS, DPhil, FRACP, Betty Raman, MBBS, FRACP, DPhil, Mark Cassar, MBBS, Stefan Neubauer, MD, FMedSCi |
2020-08-14 |
| A clinical study to assess AR-701 in the treatment of patients with COVID-19 |
Coronavirus disease 19 infection |
AR-701 alone |
COVID19 Spike glycoprotein inhibitor |
|
Aridis Pharmaceuticals Inc |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-08-14 |
| CT Abnormalities Evocative of Lung Infection Are Associated With Lower 18F-FDG Uptake in Confirmed COVID-19 Patients |
Coronavirus disease 19 infection, Lung infection |
18F-FDG alone, Vereos digital hybrid system (Philips) alone, computed tomography alone, positron emission tomography alone, viral testing alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Central Hospital, Nancy, France |
|
France |
2020-03-15 |
2020-07-30 |
2020PI153, NCT04512118 |
Phase Not Applicable |
Completed |
0 |
4 Months |
22 |
Antoine VERGER |
2020-08-14 |
| Dysphagia Management During COVID-19 Pandemic |
Coronavirus disease 19 infection, Dysphagia |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Hacettepe University |
|
Turkey |
2020-08-20 |
2020-11-30 |
DYSPHAGIA DURING COVID-19, NCT04509752 |
Phase Not Applicable |
Not yet recruiting |
0 |
3 Months |
50 |
NUMAN DEMİR, SELEN SEREL ARSLAN |
2020-08-14 |
| Phase I/II Trial of Povidone-iodine (PVP-I) Nasal Swab For Preventing COVID-19 Spread in Healthy Subjects |
Coronavirus disease 19 infection |
povidone-iodine alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Brigham & Women's Hospital |
3M Co |
US |
2020-08-31 |
2021-04-30 |
2020P002323, NCT04510402 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
0 |
8 Months |
50 |
Mark D Hornstein, MD, Raymond M Anchan, MD, PhD, Raymond Manohar Anchan, M.D.,Ph.D. |
2020-08-14 |
| A phase III clinical trial to assess Ad5-nCOV for the treatment of patients with COVID-19 infection |
Coronavirus disease 19 infection |
Ad5-nCoV alone |
COVID19 Spike glycoprotein modulator |
|
CanSino Biologics Inc |
|
Saudi Arabia |
|
|
|
Phase 3 Clinical |
Planned |
0 |
|
5000 |
|
2020-08-14 |
| CHARTER-Irl: Nebulized Heparin to Reduce COVID-19 Induced Acute Lung Injury |
Acute lung injury, Coronavirus disease 19 infection |
nebulized unfractionated heparin alone, standard care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University College Galway |
|
Ireland |
2020-09-30 |
2022-01-31 |
CHARTER-Irl, NCT04511923, NUIG-2020-003 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
0 |
16 Months |
40 |
David Cosgrave, John Laffey |
2020-08-14 |
| Transparent Elastomeric Respirator for Aerosol-based Protection |
Coronavirus disease 19 infection |
reusable elastomeric respirator with dual N95 filter alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Brigham & Women's Hospital |
Massachusetts General Hospital, Memorial Sloan-Kettering Cancer Center |
US |
2020-07-25 |
2020-12-31 |
2020P000852, NCT04511390 |
Phase Not Applicable |
Recruiting |
0 |
5 Months |
100 |
C. Giovanni Traverso, Giovanni Traverso, MB, BChir, PhD, Manish Gala, MD, Paul Zel |
2020-08-14 |
| LOSVID: Losmapimod Safety and Efficacy in COVID-19 |
Coronavirus disease 19 infection, Inflammatory disease, Respiratory failure |
losmapimod alone, standard of care alone |
Double homeobox protein 4 inhibitor, p38 MAP kinase alpha inhibitor, p38 MAP kinase beta inhibitor, p38 MAP kinase inhibitor |
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fulcrum Therapeutics Inc |
|
Mexico, US, Brazil |
2020-08-31 |
2020-11-30 |
FIS-001-2020, LOSVID, NCT04511819 |
Phase 3 Clinical |
Not yet recruiting |
0 |
3 Months |
410 |
Call Center, Daniela Pereira Mendes, David Rubio, MD, Diego Cadavid, MD, Folusakin Ayoade, MD, Iram Abbasi, Jose' Flores, MD, Karel Calero, MD, Natiana Nalin Vizioli, Rayo Morfin, MD, Rebecca Zash, MD, Rosie Magallon, Veronica Martin |
2020-08-14 |
| RESCUE: A Study to Evaluate the Safety and Efficacy of Razuprotafib, a Novel Tie 2 Activator, in Hospitalized Subjects With Moderate to Severe Coronavirus Disease 2019 (COVID-19) |
Coronavirus disease 19 infection |
razuprotafib alone |
Protein tyrosine phosphatase beta inhibitor, Tek tyrosine kinase receptor stimulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Aerpio Therapeutics Inc |
Medical Technology Enterprise Consortium |
|
2020-09-30 |
2021-02-28 |
AKB-9778-CI-6001, NCT04511650, RESCUE |
Phase 2 Clinical |
Not yet recruiting |
0 |
5 Months |
180 |
Ashley Best, PhD |
2020-08-14 |
| Bicalutamide to Block TMPRSS2 in Males With COVID-19 Infection |
Coronavirus disease 19 infection |
bicalutamide alone |
Androgen receptor antagonist |
Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Florida |
|
US |
2020-09-30 |
2022-09-30 |
IRB202001669-A, NCT04509999, OCR38162 |
Phase 3 Clinical |
Not yet recruiting |
0 |
24 Months |
100 |
Elizabeth Piantadosi, Frederic Kaye, MD |
2020-08-14 |
| Evaluation of the effectiveness of hydroxychloroquine and clarithromycin in dyspnea and cough caused by COVID-19 in recovery phase |
Coronavirus disease 19 infection, Cough, Dyspnea |
clarithromycin (Tehran shimi company) alone, hydroxychloroquine (Rooz daroo company) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Iran University of Medical Sciences |
|
Iran |
2020-08-22 |
|
IR.IUMS.FMD.REC.1399.244, IRCT20200718048129N1 |
Phase 3 Clinical |
Not yet recruiting |
0 |
|
45 |
Dr Sima Bahrami, Dr. Seyed Abbas Motavlian, Sima Bahrami |
2020-08-14 |
| Helmet versus Face Mask in Patients With Acute Respiratory Distress Syndrome |
Coronavirus disease 19 infection, Respiratory distress syndrome |
non invasive ventilation via helmet alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hamad Medical Corp |
|
Qatar |
2020-08-31 |
2021-08-31 |
MRC-01-20-616, NCT04507802 |
Phase Not Applicable |
Not yet recruiting |
0 |
12 Months |
60 |
Abdulqadir J Nashwan, MSc, Abdulqadir J. Nashwan, MSc, Ahmed A Soliman, BSc, Ahmed S Mohamed, BSc, Ahmed S. Mohamed, BSc, Dore C Ananthegowda, MD, Hani S Elzeer, MD, Karimulla S Shaik, MD, Mohamad Y Khatib, MD, Mohamed Z Peediyakkal, MD, Moustafa S Elshafei, MD, Muhsen A Shahen, MD, Nevin Kannappilly, MD, Wael I Abdaljawad, MD |
2020-08-13 |
| Evaluating the effectiveness of intravenous ozonized saline in COVID-19 disease |
Coronavirus disease 19 infection |
Medozon device alone, Variable regimens including IFN beta-1a , IFN beta-1b , atazanavir + ritonavir , chloroquine phosphate , dexamethasone , enoxaparin sodium , heparin , hydroxychloroquine , lopinavir + ritonavir , ozonized saline |
HIV protease inhibitor, Low molecular weight heparin |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Ahvaz University of Medical Sciences |
|
Iran |
2020-08-22 |
|
IR.AJUMS.REC.1399.363, IRCT20200730048253N1 |
Phase 3 Clinical |
Not yet recruiting |
0 |
|
60 |
Dr. mohammad Badavi, Dr.Najme dareini, Najme dareini, Shokrollah Salmanzadeh Ramhormozi |
2020-08-13 |
| ONCOVID-21: Evaluation of a ddPCR Technology for the SARS-CoV-2 Detection in Symptomatic Patients With Suspicion of COVID-19 |
Coronavirus disease 19 infection |
Bio-Rad SARS-CoV-2 ddPCR Test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Leon Berard |
|
France |
2020-09-30 |
2021-03-31 |
NCT04510454, ONCOVID-21, ONCOVID-21 - ET20-118 |
Phase Not Applicable |
Not yet recruiting |
0 |
6 Months |
200 |
Bénédicte MASTROIANNI, MD, Ellen BLANC |
2020-08-13 |
| Profile of hospitalized patients with Covid-19 and repercussions of physiotherapy |
Coronavirus disease 19 infection |
physiotherapy alone |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo |
|
Brazil |
2020-06-18 |
|
33351020.2.0000.0068, 4.091.795, 4.172.084, RBR-2f9k8p, U1111-1255-6608 |
Phase Not Applicable |
Recruiting |
1 |
|
2000 |
Clarice Tanaka |
2020-08-14 |
| A survey to analyze the understanding about the use of face mask among the general public during COVID 19 |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Kasturba Medical College and Hospital |
|
India |
2020-08-20 |
|
CTRI/2020/08/027046 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
697 |
Dr Ranita Ghosh Dastidar, Dr Vaishali K |
2020-08-14 |
| Nursing students perception of out of the classroom learning during the period of COVID-19 |
Coronavirus disease 19 infection |
|
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Manipal College of Nursing |
|
India |
2020-08-31 |
|
CTRI/2020/08/027047 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
380 |
Linu Sara George, Prima Jenevive Jyothi DSouza |
2020-08-14 |
| Yoga for Police personnel |
Coronavirus disease 19 infection |
Pranayama and Yoga Nidra alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Sri Devaraj Urs Academy of Higher Education and Research |
|
India |
2020-08-17 |
|
CTRI/2020/08/027048 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
60 |
Dr Patil NJ |
2020-08-14 |
| Effect of hemoperfusion on short-term outcome of critical ill COVID-19 |
Acute stress disorder, Coronavirus disease 19 infection, Delirium |
ABCDE protocol alone, CytoSorb filter alone, anticoagulant therapy alone, antiviral therapy alone, blood sugar management alone, complementary medication therapy alone, corticosteroid therapy alone, face mask alone, hemoperfusion therapy alone, heparin alone, low tidal volume ventilation alone, non-invasive mechanical ventilation alone, proton pump inhibitor therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Tabriz University of Medical Sciences |
|
Iran |
2020-08-22 |
|
IR.TBZMED.REC.1399.493, IRCT20091012002582N22 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
160 |
Ata Mahmoodpoor, Dr. khosro Adibkia, Mojtaba Mohammadzadeh |
2020-08-14 |
| Study of families who travelled from another place and had COVID-19 |
Coronavirus disease 19 infection |
|
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Dr TMA Pai Hospital |
|
India |
2020-08-20 |
|
CTRI/2020/08/027049 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
19 |
Shashikiran Umakanth |
2020-08-13 |
| PPE Study: Assessment of PPE usage pattern and the associated Surgeon Discomfort and Fatigue Study |
Coronavirus disease 19 infection, Fatigue |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Tata Memorial Centre |
|
India |
2020-08-20 |
|
CTRI/2020/08/027050, PPE Study |
Phase Not Applicable |
Not yet recruiting |
1 |
|
500 |
DrShivakumar Thiagarajan |
2020-08-13 |
| Survey of challenges faced by pain and palliative physicians working in cancer set up during corona virus disease time |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
All India Institute of Medical Sciences |
|
India |
2020-08-10 |
|
CTRI/2020/08/027051 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
200 |
Dr Seema Mishra |
2020-08-13 |
| Evaluation of the effect of curcumin in improving patients with covid -19 |
Coronavirus disease 19 infection |
curcumin-piperine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Bandare-abbas University of Medical Sciences |
|
Iran |
2020-08-05 |
|
IR.HUMS.REC.1399.187, IRCT20200514047445N1 |
Phase 3 Clinical |
Recruiting |
1 |
|
60 |
Majid Teremmahi Ardestani, Timur Agha Molai |
2020-08-13 |
| GlobalSurg-CovidSurg Week |
Coronavirus disease 19 infection |
surgery alone |
|
|
The University of Birmingham |
Association of Coloproctology of Great Britain and Ireland, Bowel Disease Research Foundation of ACPGBI, Bowel and Cancer Research, British Association of Surgical Oncology: Breast Group, British Gynaecological Cancer Society, European Society of Coloproctology, NIHR Academy, National Institute for Health Research (NIHR), Sarcoma UK, Vascular Society for Great Britain and Ireland, Yorkshire Cancer Research |
UK |
2020-10-01 |
2020-12-01 |
GS-CSWEEK.20200713, NCT04509986 |
Phase Not Applicable |
Not yet recruiting |
0 |
2 Months |
1000 |
Aneel Bhangu, PhD, Dmitri Nepogodiev, Master |
2020-08-13 |
| Virtual Teaching Kitchen |
Coronavirus disease 19 infection, Metabolic syndrome X |
Virtual Nutritional Education alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Boston University |
|
US |
2020-09-30 |
2021-06-30 |
H-39597, NCT04509206 |
Phase Not Applicable |
Not yet recruiting |
0 |
9 Months |
25 |
Iniya Rajendran, Naomi M Hamburg, MD |
2020-08-14 |
| KAND-567 Versus Placebo in Subjects Hospitalized with COVID-19. A Phase II, Randomized, two-Arm, Parallel-Group, Double-blind Study to Evaluate Efficacy, Safety, Tolerability, and Pharmacokinetics |
Coronavirus disease 19 infection |
KAND-567 alone, best standard treatment alone |
CX3CR1 chemokine antagonist, Fractalkine ligand inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kancera AB |
Capio S:t Görans Hospital, Scandinavian CRO, Scandinavian Development Services AB, Science For Life Laboratory |
Sweden |
2020-07-02 |
|
2020-002322-85, KAN0006 |
Phase 2 Clinical |
Recruiting |
1 |
|
40 |
Anna Runeson |
2020-08-14 |
| Effect of erythropoietin on COVID-19 |
Coronavirus disease 19 infection, Hypoxia, Lung disease, Lymphocytopenia, Tachypnea |
Variable regimens including atazanavir , atazanavir + ritonavir , chloroquine phosphate , enoxaparin sodium , epoetin alfa (Procrit/Eprex), Johnson & Johnson , hydroxychloroquine sulfate , lopinavir + ritonavir |
Erythropoietin ligand, HIV GAG POL polyprotein inhibitor, HIV GAG protein inhibitor, HIV protease inhibitor, HIV-1 protease inhibitor, Low molecular weight heparin |
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Bandare-abbas University of Medical Sciences |
|
Iran |
2020-06-21 |
|
IR.HUMS.REC.1399.165, IRCT20200509047364N1 |
Phase 2 Clinical |
Recruiting |
1 |
|
20 |
Dariush Hooshyar, Dr. Mehdi Hassaniazad, Dr. Mitra Kazemijahromi, Dr. Teamur Aghamolaei |
2020-08-14 |
| Evaluation of the effect of shallomin on the treatment and improvement of symptoms in patients with Covid 19 |
Coronavirus disease 19 infection, Respiratory disease |
approved COVID19 protocol treatment alone, shallomin (Sadra Noor Biotechnology Pharmaceutical Company) alone |
|
|
Dezful University of Medical Sciences |
|
Iran |
2020-08-10 |
|
IR.DUMS.REC.1399.014, IRCT20200725048199N1 |
Phase 2 Clinical |
Recruiting |
0 |
|
146 |
Mahnaz Nosratabadi, Maysam Mardsoltani, mahnaz nosratabadi |
2020-08-13 |
| ARBS CORONA I: Host-Response Mediators in Coronavirus (COVID-19) Infection |
Coronavirus disease 19 infection |
angiotensin II type 1 receptor blocker therapy alone, angiotensin-converting enzyme inhibitor therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of British Columbia |
British Columbia Centre for Disease Control, Canadian Institutes of Health Research, McGill University Health Center, Peking Union Medical College Hospital, Research Institute of the McGill University Health Centre, University of Alberta, University of Calgary, University of Ottawa, University of Pennsylvania, University of Toronto, University of Victoria, Wuhan University |
Canada |
2020-03-17 |
2022-06-30 |
ARBS CORONA I, H20-00600, NCT04510623 |
Phase Not Applicable |
Recruiting |
15 |
27 Months |
500 |
Allison McGeer, MD, Ari Joffe, MD, Brent Winston, MD, David Maslove, MD, David Sweet, MD, Francois Lamontagne, MD, Gregory Haljan, MD, James A Russell, MD, Jim Russell, John Marshall, MD, Lynda Lazosky, Matthew Cheng, MD, Nataly Farshait, Oleksa Rewa, MD, Puneet Mann, MSc, Robert Fowler, MD, Todd Lee, MD |
2020-08-14 |
| Canine COVID-19 Detection |
Coronavirus disease 19 infection |
traditional sniffer dog medical-detection alone |
|
Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Arthropod Control Product Test Center (ARCTEC) |
Cardiff University, Medical Detection Dogs, University of Durham |
UK |
2020-07-02 |
2020-10-31 |
LSH1285, NCT04509713 |
Phase 1 Clinical |
Recruiting |
1 |
3 Months |
16250 |
James Logan, James Logan, PHD |
2020-08-14 |
| A phase III clinical trial of Brexanolone in patients with advanced COVID-19 related acute respiratory distress syndrome (ARDS) |
Coronavirus disease 19 infection, Respiratory distress syndrome |
brexanolone alone |
GABA A receptor modulator |
|
SAGE Therapeutics Inc |
|
|
2020-12-31 |
|
|
Phase 3 Clinical |
Planned |
0 |
|
|
|
2020-08-13 |
| COVIDSTEROID2: Higher Versus Lower Doses of Dexamethasone for COVID-19 and Severe Hypoxia |
Coronavirus disease 19 infection, Hypoxia |
betamethasone alone, dexamethasone (Dexavit) alone, standard care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Scandinavian Critical Care Trials Group |
Aalborg Universitetshospital, Aarhus University Hospital, Centre for Research in Intensive Care (CRIC), Copenhagen Trial Unit, Rigshospitalet, Denmark, The George Institute for International Health |
Switzerland, Denmark, India, Sweden |
2020-08-17 |
2022-02-17 |
2020-003363-25, 2020-07-16, COVIDSTEROID2, H-20051056, NCT04509973, RH-ITA-009 |
Phase 3 Clinical |
Not yet recruiting |
51 |
18 Months |
1000 |
Amit Shobhavat, Anders Møller, Anders Perner, MD PhD, Anders Perner, MD, PhD, Professor, Andreas Wiklund, Anna Nilsson, Anne Sofie Andreasen, Bharath KT Vijayaraghavan, Binila Chacko, Buster Mannheimer, Carl-Johan Treutiger, Farhad Kapadia, Fredrik Schiöler, Fredrik Sjövall, Iben S Darfelt, J V Divatia, Jacob Hollenberg, Jonathan Oras, Kapil Boraoke, Kedar Toraskar, Magnus Gisslen, Magnus Hedenstierna, Margit Smitt, MD, Marie Warrer B Petersen, MD, Marie Warrer Petersen, MD, Michelle Chew, Neeta B Nayak, Olof Wall, Omender Singh, Pontus Naucler, Pravin Amin, Rajesh Chawla, Saif M Khan, Sanjith Saseedharan, Sara Tehrani, Syed M Ahmed, Thomas Mohr, Urvi Shukla, Vibeke RL Jørgensen, MD, PhD, Zubair U Mohamed, Åke Norberg |
2020-08-14 |
| Ivermectin Nasal Spray for COVID-19 Patients |
Coronavirus disease 19 infection |
ivermectin alone, standard care alone |
Chloride channel modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Tanta University |
|
Egypt |
2020-09-30 |
2020-12-31 |
IVRINH, NCT04510233 |
Phase 2 Clinical |
Not yet recruiting |
1 |
3 Months |
60 |
Kamal Okasha, PhD, Nahla El-Ashmawy, PhD |
2020-08-14 |
| Characterizing the Immune Response and Neuronal Damage in COVID-19 |
Coronavirus disease 19 infection, Inflammatory disease, Nerve injury |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Inselspital, Berne |
University of Bern |
Switzerland |
2020-03-05 |
2021-03-05 |
NCOV19, NCT04510012 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
150 |
Cédric Hirzel, MD, Denis Grandgirard, PhD, Franziska Suter, PhD, Jörg C Schefold, MD, Leib L Stephen, MD, Ronald Dijkman, PhD, Thibaud Spinetti, PhD |
2020-08-14 |
| COVID SAFE: COVID SAFE Enrollment |
Coronavirus disease 19 infection |
Opt-in Recruitment Email alone, Opt-out Recruitment Email alone, saliva-based viral testing alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Pennsylvania |
|
US |
2020-08-31 |
2020-09-30 |
843565, COVID SAFE, NCT04506268 |
Phase Not Applicable |
Not yet recruiting |
0 |
1 Month |
1200 |
Chalanda N Evans, BS, Mitesh S Patel, MD |
2020-08-14 |
| RAAS-COVID: The McGill RAAS-COVID-19 Randomized Controlled Trial |
Coronavirus disease 19 infection, Viral pneumonia |
anti-hypertensive medication alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Research Institute of the McGill University Health Centre |
McGill University Health Center, Sir Mortimer B Davis Jewish General Hospital, Université De Lorraine |
Canada |
2020-08-01 |
2021-09-01 |
MP-37-2021-6614, NCT04508985, RAAS-COVID |
Phase Not Applicable |
Not yet recruiting |
1 |
13 Months |
40 |
Abhinav Sharma, MD, Julie Lebel, PM |
2020-08-14 |
| Technology-assisted Index on Improving Hand Hygiene of Registered Nurses |
Coronavirus disease 19 infection |
3M Clean-Trace Surface ATP test alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Taiwan University Hospital |
|
Taiwan |
2020-08-31 |
2022-05-31 |
202006019RINB, NCT04508114 |
Phase Not Applicable |
Not yet recruiting |
1 |
21 Months |
120 |
Man-Rong Hsu, BSN, Wei-Wen Wu, PhD |
2020-08-13 |
| CoviDep: Treatment of Depressive Symptoms in Older Individuals in Isolation During Covid-19 |
Coronavirus disease 19 infection, Depression |
Brief Behavioral Activation with Mental Imagery alone |
|
Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Uppsala University |
Vastmanland County Council (Landstinget) |
Sweden |
2020-08-31 |
2021-07-31 |
2020-02079, CoviDep, NCT04508868 |
Phase Not Applicable |
Not yet recruiting |
0 |
11 Months |
154 |
Johnny Pellas, MSc, Mattias Damberg, MD, PhD |
2020-08-14 |
| COVID-19 GDI: COVID-19 Germ Defence: a website to improve infection control during the COVID-19 pandemic |
Coronavirus disease 19 infection, Influenza virus infection, Respiratory tract infection |
COVID-19 Germ Defence website alone, digital behavioral change intervention alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Bristol |
NIHR Health Protection Research Unit (HPRU) in Behavioural Science and Evaluation, National Institute for Health Research, Applied Research Collaboration West (NIHR ARC West), United Kingdom Research & Innovation |
UK |
2020-03-30 |
2021-04-30 |
COVID-19 GDI, CPMS 46740, IRAS 287978, ISRCTN14602359, UKRI (MRC) MC_PC_19068, UOB 2020-3213 |
Phase Not Applicable |
Not yet recruiting |
0 |
13 Months |
6822 |
Dr Jeremy Horwood, Dr Melanie Chalder |
2020-08-13 |
| OMA-COVID-19: Effect of the anti-inflammatory test drug anakinra in patients with coronavirus (COVID-19) requiring oxygen support |
Coronavirus disease 19 infection, Inflammatory disease, Respiratory distress syndrome, Viral pneumonia |
anakinra alone |
Type I IL-1 receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sultan Qaboos University |
|
Oman |
2020-05-25 |
2020-08-15 |
ISRCTN74727214, OMA-COVID-19 |
Phase 2 Clinical |
No longer recruiting |
2 |
2 Months |
75 |
Dr Balkhair |
2020-08-14 |
| Japan COVID-19 Study of the psychosocial impacts of the postponement/cancellation of reproductive medicine |
Acute stress disorder, Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Dokkyo Medical University, Saitama Medical Center, Japan |
Japan Society for Reproductive Psychology |
Japan |
2020-08-17 |
|
UMIN000041387 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1100 |
Kouhei Sugimoto, Tomoe Koizumi |
2020-08-14 |
| COVER: Randomized, Double-blind, Multi Centre Phase II, Dose Finding Clinical Trial on Ivermectin for the early Treatment of COVID-19 Studio clinico randomizzato, in doppio cieco, multicentrico, di fase II, per l'individuazione del dosaggio di impiego dell'Ivermectina per il trattamento precoce del COVID-19 |
Coronavirus disease 19 infection |
ivermectin alone |
Chloride channel modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ospedale Sacro Cuore don Calabria |
|
Italy |
2020-06-12 |
|
2020-002283-32, 2020-34, COVER |
Phase 2 Clinical |
Recruiting |
1 |
|
122 |
Unità per la Ricerca Clinica |
2020-08-13 |
| Camphora in COVID: A clinical study to evaluate efficacy and safety of Camphora tablets in Covid positive patients |
Coronavirus disease 19 infection |
Camphora alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
TNMC and BYL Nair Hospital |
|
India |
2020-08-17 |
|
CTRI/2020/08/027045, Camphora in COVID |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
|
Dr Ashish Agarwal, Dr Renuka Munshi |
2020-08-13 |
| Performance Assessment of SARS-CoV-2 Detection Breath Biopsy - SARS-CoV-2 Study (COVID) |
Coronavirus disease 19 infection |
breath biopsy face masks with removable filters and fitted PVA strip alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Owlstone Nanotech Inc |
Onze Lieve Vrouwe Gasthuis Amsterdam, Universiteit Maastricht |
|
2020-08-31 |
2020-12-31 |
NCT04508556, SARS-COV-2 STUDY |
Phase Not Applicable |
Not yet recruiting |
0 |
4 Months |
500 |
Alexandra DeSaedeleer, Amerjit kang, Paul Bresser, Paul Savelkoul, |
2020-08-13 |
| To observe the outcome of Classical Ayurvedic medicine for the treatment of COVID-19 |
Coronavirus disease 19 infection |
Maha-Sudarshana Ghan Vati alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Shri Krishna Ayush University |
|
India |
2020-08-14 |
|
CTRI/2020/08/027044 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
100 |
Professor Dr Anil Sharma, Professor Dr Ashish Mehta, Professor Dr Baldev Kumar |
2020-08-13 |
| COREG: The McMaster Multi-Regional COVID-19 Hospital Case Registry |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
McMaster University |
Canadian Institutes of Health Research, Grand River Hospital, Hamilton Academic Health Sciences Organization, Hamilton Health Sciences Corp, Niagara Health System, St Josephs Healthcare Hamilton, St. Mary’s General Hospital |
Canada |
2020-04-15 |
2021-07-31 |
172754, COREG, NCT04508959 |
Phase Not Applicable |
Recruiting |
4 |
15 Months |
1500 |
Andrew P Costa, PhD, Darly Dash, MSc, Jessica Kapralik, MD (PGY5), Marla Beauchamp, PhD, Mats L Junek, MD, MSc, MyLinh Duong, MBBS, MSc, FRACP, Rebecca J Kruisselbrink, MD, MPH, FRCPC, Terence Ho, MD, FRCP, Tyler Pitre, MA, MD (PGIM) |
2020-08-13 |
| PREVENT-HD: A Study of Rivaroxaban to Reduce the Risk of Major Venous and Arterial Thrombotic Events, Hospitalization and Death in Medically Ill Outpatients With Acute, Symptomatic Coronavirus Disease 2019 (COVID-19) Infection |
Cerebrovascular disease, Coronary artery disease, Coronavirus disease 19 infection, Ischemic stroke, Peripheral vascular disease, Thromboembolism |
rivaroxaban alone, standard of care alone |
Factor Xa antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Janssen Research & Development LLC |
|
US |
2020-08-12 |
2021-04-06 |
39039039DVT3004, CR108849, NCT04508023, PREVENT-HD |
Phase 3 Clinical |
Not yet recruiting |
3 |
7 Months |
4000 |
Study Contact |
2020-08-13 |
| A clinical trial of eravacycline for potential treatment of SARS-CoV-2 infection (COVID-19) |
Coronavirus disease 19 infection |
repurposed eravacycline (COVID-19), SOM Biotech alone |
COVID19 replicase polyprotein 1a inhibitor, COVID19 replicase polyprotein 1ab inhibitor, Viral protease inhibitor |
|
SOM Biotech SL |
|
US, Europe |
|
|
|
Phase Not Applicable |
Planned |
1 |
|
|
|
2020-08-12 |
| Study to Evaluate the Safety, Tolerability and Pharmacokinetics of AZD-7442 in Healthy Adults |
Coronavirus disease 19 infection |
AZD-7442 alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
AstraZeneca plc |
PAREXEL International |
UK |
2020-08-17 |
2021-09-14 |
D8850C00001, NCT04507256 |
Phase 1 Clinical |
Not yet recruiting |
1 |
12 Months |
48 |
AstraZeneca Clinical Study Information Center, Muna Albayaty, MBChB, FFPM, MSc |
2020-08-13 |
| Electronic Stethoscope Use During Intubation in Full Personal Protective Equipment |
Coronavirus disease 19 infection, Surgical procedure |
auscultation alone, electronic stethoscope alone, endobronchial blocker alone, endotracheal tube alone, fiberscope alone, general anesthesia alone, traditional stethoscope alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Taiwan University Hospital |
|
Taiwan |
2020-08-14 |
2021-07-31 |
202005104RINC, NCT04507958 |
Phase Not Applicable |
Not yet recruiting |
1 |
11 Months |
80 |
Chun-Yu Wu, PhD |
2020-08-14 |
| Online meditation as an aid in reducing symptoms of Depression, Anxiety and Psychological Stress in Resident Physicians during COVID-19 pandemic in Brazil |
Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression |
on-line meetings for meditation training alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
University of Sao Paulo |
|
Brazil |
2020-07-20 |
2020-09-30 |
33585620.0.0000.0045, 4.129.324, RBR-2w7ghc, U1111-1255-3186 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
44 |
Maria do Rosário Toscano von Flach |
2020-08-13 |
| A Survey to Assess Effects of Covid-19 on Cardiovascular Patients |
Cardiac failure, Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centro en Insuficiencia Cardiaca |
Fundación Clínica Médica Sur, Instituto Nacional de Cardiologia Ignacio Chavez |
Mexico |
2019-05-15 |
2021-07-15 |
20-1156, NCT04508920 |
Phase Not Applicable |
Recruiting |
1 |
26 Months |
76 |
ALAN FUENTES, MD, ALAN FUENTES-MENDOZA, MD, CHUQUIURE-VALENZUELA EDUARDO, MD, MSc, EDUARDO CHUQUIURE-VALENZUELA, MD, EDUARDO CHUQUIURE-VALENZUELA, MD MSc |
2020-08-13 |
| COVID SAFE: COVID-19 Screening Assessment for Exposure |
Coronavirus disease 19 infection |
saliva-based testing alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Pennsylvania |
|
US |
2020-08-31 |
2021-03-31 |
843565-OBS, COVID SAFE, NCT04508777 |
Phase Not Applicable |
Not yet recruiting |
1 |
7 Months |
600 |
Chalanda N Evans, BS, Mitesh S Patel, MD |
2020-08-14 |
| Effect of the Use of Anticoagulant Therapy During Hospitalization and Discharge in Patients With COVID-19 Infection |
Coronavirus disease 19 infection |
enoxaparin sodium alone |
Low molecular weight heparin |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Regional de Alta Especialidad de Ixtapaluca |
|
Mexico |
2020-06-20 |
2020-12-30 |
NCT04508439, NR-CEI-HRAEI-19-2020 |
Phase 2 Clinical |
Recruiting |
1 |
6 Months |
130 |
Omar O Ramos-Peñafiel, Omar Ramos-Peñafiel, Omar Ramos-Peñafiel, MD, PhD |
2020-08-13 |
| A clinical study to assess IgG1 Ab1 for the potential treatment of SARS-CoV-2 infection |
Coronavirus disease 19 infection |
IgG1 Ab1(COVID-19 infection) Abound bio/Saudivax alone |
|
|
University of Pittsburgh Medical Center |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-08-12 |
| Long-term Outcomes in Patients With COVID-19 |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Renji Hospital |
|
China |
2020-08-10 |
2021-08-31 |
COVID-19 PROGNOSIS, NCT04508712 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
900 |
Diansan Su, MD,PhD, Weifeng Yu, MD,PhD |
2020-08-13 |
| COVID-19 Associated Coagulopathy in Egypt |
Blood clotting disorder, Coronavirus disease 19 infection |
|
|
|
Assiut University |
|
Egypt |
2020-08-07 |
2020-10-31 |
17300413, NCT04507230 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
100 |
Azza Abdelaal, MD, PhD, Azza Ezzeldin, MD,PhD, Hanan Galal, MD, PhD |
2020-08-13 |
| MITIGATE COVID-19: A Pragmatic, Randomized Trial of Icosapent Ethyl for High-Cardiovascular Risk Adults in the Era of Coronavirus Disease 2019 |
Atherosclerosis, Coronavirus disease 19 infection, Influenza virus infection, Ischemic stroke, Myocardial infarction, Peripheral vascular disease, Upper respiratory tract infection |
icosapent ethyl, Amarin alone |
Apolipoprotein B antagonist, Phospholipase A2 inhibitor |
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kaiser Permanente |
Amarin Corp plc |
US |
2020-08-07 |
2023-02-28 |
1597940, MITIGATE COVID-19, NCT04505098 |
Phase 4 Clinical |
Recruiting |
1 |
30 Months |
16500 |
Alan Go, MD, Alan S Go, M.D., Andrew Ambrosy, M.D., Andrew P Ambrosy, M.D. |
2020-08-14 |
| The C3I COVID-19 Project |
Coronavirus disease 19 infection, Dyspnea, Viral pneumonia |
|
|
|
University of Wisconsin-Madison |
National Cancer Institute |
US |
2020-08-10 |
2021-12-31 |
2020-069, A534253, CTRI, NCT04506528, OISE-20-66590-1, SMPH/MEDICINE |
Phase Not Applicable |
Recruiting |
26 |
16 Months |
170000 |
Amy Conlon, MPH, Betsy Rolland, PhD, MLIS, MPH, Michael C Fiore, MD, MPH, MBA, Rob Adsit, MEd, Stevens S Smith, PhD, Tanya R Schlam, PhD |
2020-08-13 |
| EXPLORE COVID-19: An exploratory translational research study to analyze the immune response of COVID-19 patients at varying stages of disease |
Coronavirus disease 19 infection |
|
|
|
Innate Pharma SA |
Assistance Publique Hopitaux De Marseille, Hôpital de la Timone (UPCET/CIC) |
|
|
|
EXPLORE COVID-19 |
Phase Not Applicable |
Status not specified |
0 |
|
|
|
2020-08-12 |
| COVRehab: The Usability, Feasibility and Tolerability of Virtual Reality for Rehabilitation From COVID-19 |
Cognitive disorder, Coronavirus disease 19 infection, Psychiatric disorder |
cognitive rehabilitation alone, physical rehabilitation alone, psychological rehabilitation alone, standard physiotherapy alone, virtual reality headset rehabilitation alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Radboud University |
|
Netherlands |
2020-09-01 |
2021-01-01 |
COVREHAB, COVRehab, NCT04505761 |
Phase Not Applicable |
Not yet recruiting |
1 |
4 Months |
40 |
Bart Staal, PT, PhD, Harry van Goor, MD, PhD, Merlijn Smits, Msc |
2020-08-12 |
| Effect of a Nss to Reduce Complications in Patients With Covid-19 and Comorbidities in Stage III |
Coronavirus disease 19 infection, Respiratory distress syndrome |
macronutrient intake alone, nutritional support system alone, standard diet alone, Variable regimens including Cyanomax Ultra , L-arginine , Neurobion , Saccharomyces Bourllardii , Spirulina Maxima , ascorbic acid , cholecalciferol , folic acid , glutamine , magnesium , omega 3 fatty acid , resveratrol , selenium , zinc |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Anahuac University |
|
Mexico |
2020-08-31 |
2020-12-31 |
202036, NCT04507867 |
Phase Not Applicable |
Not yet recruiting |
1 |
4 Months |
240 |
Fernado Leal Martínez, Ph.D, Fernando Leal Martínez, Ph.D |
2020-08-13 |
| Efficacy, Safety and Immunogenicity Study of SARS-CoV-2 Inactivated Vaccine (COVID-19) |
Coronavirus disease 19 infection |
CoronaVac alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Bio Farma |
National Institute Of Health Research & Development (Nihrd)- Ministry Of Health Of The Republic Of Indonesia, Sinovac Life Sciences Co., Ltd., Universitas Padjadjaran |
Indonesia |
2020-08-10 |
2021-09-30 |
COV2-0320, NCT04508075 |
Phase 3 Clinical |
Not yet recruiting |
1 |
13 Months |
1620 |
Eddy Fadlyana, MD, PhD, Novilia Sjafri Bachtiar, MD, PhD, Prof Kusnandi Rusmil, MD, PhD, Prof. Kusnandi Rusmil, MD, PhD |
2020-08-13 |
| Comparison of Extra Vascular Lung Water Index in Covid-19 ARDS and 'Typical' ARDS Patients |
Coronavirus disease 19 infection, Respiratory distress syndrome |
transpulmonary thermodilution (TPTD) technique alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Istanbul University-Cerrahpasa |
|
Turkey |
2020-09-01 |
2020-12-31 |
0308202247, NCT04508933 |
Phase Not Applicable |
Not yet recruiting |
1 |
4 Months |
10 |
Olcay Dilken, MD, Yalım Dikmen, Prof |
2020-08-13 |
| VOICE-COVID: The VOICE-COVID-19, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Study World Health Organization (WHO) |
Coronavirus disease 19 infection |
Alexa (Amazon) alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
McGill University Health Center, Research Institute of the McGill University Health Centre |
Amazon Web Services |
Canada |
2020-07-01 |
2020-11-01 |
2020-6583, NCT04508972, VOICE-COVID |
Phase Not Applicable |
Recruiting |
1 |
4 Months |
50 |
Abhinav Sharma, MD, Abhinav h Sharma, MD, Julie Lebel |
2020-08-14 |
| Bursa Postgraduate Hospital |
Coronavirus disease 19 infection |
low molecular weight heparin alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Bursa Postgraduate Hospital |
|
Turkey |
2020-05-15 |
2020-07-15 |
BURSA POSTGRADUATE HOSPITAL, NCT04507282 |
Phase Not Applicable |
Completed |
1 |
2 Months |
80 |
Hasan ARI |
2020-08-13 |
| Mesenchymal Stem Cell Therapy For Covid 19 |
Coronavirus disease 19 infection, Viral pneumonia |
mesenchymal stem cells therapy alone, standard care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Neurogen Brain and Spine Institute, Reelabs Private Ltd |
|
India |
2020-08-10 |
|
CT-06/2020, CTRI/2020/08/027043 |
Phase 1 Clinical |
Not yet recruiting |
1 |
|
20 |
Dr Abhijit Bopardikar, Dr Alok Sharma, Dr Rohit Kulkarni |
2020-08-13 |
| Comparison Between Positive and Negative COVID-19 Pneumonia |
Coronavirus disease 19 infection, Respiratory disease, Viral pneumonia |
PCR assay alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Palermo |
|
Italy |
2020-03-15 |
2020-12-01 |
ACPM26, NCT04507893 |
Phase Not Applicable |
Recruiting |
3 |
8 Months |
80 |
Antonio Carroccio, MD, Enzo M Farinella, MD, Giuseppe Arcoleo, MD, Pasquale Mansueto, Clinical Professor |
2020-08-13 |
| A compassionate-use study evaluating narsoplimab, Omeros investigational human monoclonal antibody targeting mannan-binding lectin-associated serine protease-2 (MASP-2), in the treatment of COVID-19 patients with Acute Respiratory Distress Syndrome (ARDS) |
Coronavirus disease 19 infection, Respiratory distress syndrome |
narsoplimab alone |
Complement cascade inhibitor, Mannan-binding lectin serine protease-2 inhibitor |
Middle-aged Adults (45-64 yrs) |
Omeros Corp |
|
Italy |
|
|
|
Phase not specified |
Status not specified |
1 |
|
|
Alessandro Rambald |
2020-08-13 |
| PSIMCOV: Psychological Impact of COVID-19 Pandemic in Healthcare Workers |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Hospital General Universitario de Valencia |
|
Spain |
2020-04-09 |
2020-04-30 |
COV2-2020, NCT04506515, PSIMCOV |
Phase Not Applicable |
Completed |
1 |
|
3000 |
Carolina Soledad Romero Garcia, MD, PhD |
2020-08-13 |
| Anti-thrombotics for Adults Hospitalized With COVID-19 |
Coronavirus disease 19 infection |
Variable regimens including dalteparin sodium , enoxaparin sodium , heparin , tinzaparin sodium , unfractionated heparin |
Antithrombin III, Factor IIa antagonist, Factor Xa antagonist, Low molecular weight heparin |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Pittsburgh |
National Heart Lung and Blood Institute |
US |
2020-08-31 |
2021-12-31 |
ACTIV-4 ACUTE, NCT04505774 |
Phase 4 Clinical |
Not yet recruiting |
1 |
16 Months |
2000 |
Judith Hochman, MD, Matthew Neal MD, Matthew Neal, MD |
2020-08-14 |
| Secondary attack rate of COVID-19, Kerala |
Coronavirus disease 19 infection |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Government Medical College Kannur |
|
India |
2020-09-01 |
|
CTRI/2020/08/027042 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
|
Anitha S S |
2020-08-13 |
| An Observational Study of Guduchi Extract Tablet |
Coronavirus disease 19 infection |
Guduchi extract tablet alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Ministry of Ayush |
|
India |
2020-08-15 |
|
CTRI/2020/08/027034 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1200 |
Dr Sanjay Srivastava, Prof Dr Abhimanyu Kumar |
2020-08-13 |
| etrospective Analysis of 245 COVID-19 Cases from a Government Teaching Hospital of North India |
Coronavirus disease 19 infection |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Superspeciality Pediatric hospital and Postgraduate Teaching Institute |
|
India |
2020-08-19 |
|
CTRI/2020/08/027036 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
245 |
Dr Divya Jain |
2020-08-13 |
| Effect of yoga for COVID-19 patients in addition to regular treatment |
Coronavirus disease 19 infection |
pranayama yoga nidra alone, standard care alone, yoga alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Sri Devaraj Urs Academy of Higher Education and Research |
|
India |
2020-08-17 |
|
CTRI/2020/08/027037 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
60 |
Nitin Patil |
2020-08-13 |
| Study to assess effects of nano-ozonised hydrogen peroxide nebulization on results of RT-PCR for novel coronavirus thus infectivity and clinical course among mild to moderate sick COVID-19 patients |
Coronavirus disease 19 infection |
Triozone alone, nano-ozonised hydrogen peroxide nebulization alone |
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Dr. S.N. Medical College, Jodhpur |
|
India |
2020-08-20 |
|
CTRI/2020/08/027038 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
|
Dr Ashish Gautam, Dr Prabhat Kumar Agrawal |
2020-08-13 |
| An interventional study to access the effect of ayurvedic medicine in positive cases of COVID-19 |
Coronavirus disease 19 infection |
Variable regimens including Lavangadi vati , Mahasudarshan ghana vati , Samsamani vati |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Ministry of Ayush |
|
India |
2020-08-12 |
|
CTRI/2020/08/027040 |
Phase 3 Clinical |
Not yet recruiting |
2 |
|
200 |
Dr Bishnu Choudhury, Prof Dr Pradip Kumar Goswami |
2020-08-13 |
| Clinical Trial on COVID-19 Patients to Improve Immunity |
Coronavirus disease 19 infection |
herbivor syrup alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Venkat Pharma Ltd |
|
India |
2020-08-14 |
|
CTRI/2020/08/027041, Herbovir/CT/2020 Version 1.0 |
Phase 4 Clinical |
Not yet recruiting |
1 |
|
40 |
Dr A Gopal Rao, Sri H Srinivas |
2020-08-13 |
| Multicenter, randomized, double-blind, placebo-controlled pilot study to evaluate the efficacy and safety of Treamid in the rehabilitation of patients after COVID-19 pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
|
Pharmenterprises LLC |
|
Russian Federation |
2020-08-06 |
2021-03-31 |
COVID-TRE-03 |
Phase 2 Clinical |
Status not specified |
12 |
7 Months |
67 |
|
2020-08-13 |
| ENSEMBLE: A Study of Ad26.COV2-S for the Prevention of SARS-CoV-2-Mediated COVID-19 in Adult Participants |
Coronavirus disease 19 infection |
JNJ-78436735 alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Janssen Vaccines & Prevention BV, Johnson & Johnson |
Biomedical Advanced Research and Development Authority (BARDA), Burroughs Wellcome Inc, National Institutes of Health, The Ragon Institute |
Philippines, Chile, Mexico, Ukraine, Colombia, Brazil, US, Peru, South Africa |
2020-09-05 |
2023-03-10 |
CR108876, ENSEMBLE, NCT04505722, VAC31518COV3001 |
Phase 3 Clinical |
Not yet recruiting |
178 |
30 Months |
60000 |
Janssen Vaccines & Prevention B.V. Clinical Trial, Study Contact |
2020-08-12 |
| COST-NHS: Burden for Staff Working in the NHS |
Coronavirus disease 19 infection, Psychiatric disorder |
|
|
Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sheffield Teaching Hospitals NHS Foundation Trust |
University of Sheffield |
UK |
2020-06-02 |
2022-04-26 |
COST-NHS, NCT04506632, STH21373 |
Phase Not Applicable |
Recruiting |
1 |
22 Months |
100 |
Colette Mann, Loretta Chantry-Groves, Sarah Danson, Professor |
2020-08-13 |
| STOP-Coronavirus: Clinical, Immunological, Genomic, Virological and Bioethical Actors of COVID-19 |
Coronavirus disease 19 infection |
|
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Instituto de Investigación Sanitaria de la Fundacion Jimenez Diaz |
Fundacion De Investigacion Hospital 12 De Octubre, Hospital Universitario 12 de Octubre, Hospital Universitario Infanta Elena, Hospital Universitario Virgen de la Arrixa, Instituto Murciano de Investigación Biosanitaria Virgen de la Arrixaca, Jimenez Diaz Foundation |
Spain |
2020-08-01 |
2021-08-01 |
COV20/00181, NCT04505709, STOP-CORONAVIRUS, STOP-Coronavirus |
Phase Not Applicable |
Recruiting |
4 |
12 Months |
1000 |
|
2020-08-12 |
| LPSARS2: Study of a Possible Respiratory Degradation Prognosis Caused by Biomarkers in Severe Forms of COVID-19 Pneumonia |
Coronavirus disease 19 infection, Respiratory tract infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Groupe Hospitalier Paris Saint-Joseph |
Centre Hospitalier Victor Dupouy |
France |
2020-05-14 |
2020-11-30 |
LPSARS2, LPSARS2, NCT04505605 |
Phase Not Applicable |
No longer recruiting |
1 |
6 Months |
200 |
|
2020-08-12 |
| GenCov: Genetic Mechanisms Underlying SARS-CoV-2 Infection and the Impact of COVID-19 on Cognitive Function |
Coronavirus disease 19 infection |
Whole exome sequencing alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Texas Cardiac Arrhythmia Research Foundation |
|
US |
2020-08-31 |
2021-09-30 |
GenCov, NCT04506229, TCAI_GENCOV |
Phase Not Applicable |
Not yet recruiting |
1 |
13 Months |
60 |
Andrea Natale, Bryan MacDonald, Sanghamitra Mohanty |
2020-08-12 |
| SARS-COV-2 and COVID-19 - a randomized, controlled trial (unblinded) |
Coronavirus disease 19 infection |
Variable regimens including aadathodai manapagu , amukara chooranam , kabasura kudineer , muthu parpam , nilavembu kudineer , pavala parpam , seenthil chooranam , silasathu parpam , sivanar amirtham , swasakudori maathirai , thippili rasayanam , thoothuvalai legiyam |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Government Kilpauk Medical College |
|
China |
2020-08-07 |
|
CTRI/2020/08/027033 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
100 |
Dr A Shiyam ranjith, Dr N Anbu, Dr P Vasanthamani |
2020-08-14 |
| An Open Label Physician Initiated 28 Day Phase 2a Study Of Ifenprodil On Lung Function In Confirmed Covid-19 Infected Patients With Severe Pneumonia |
Coronavirus disease 19 infection, SARS coronavirus infection |
ifenprodil alone |
Noncompetitive NMDA antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Dong-A University Hospital, NOVOTECH ASIA KOREA CO. LTD. |
Dong-A University Hospital |
South Korea |
2020-09-30 |
|
AGN120-2, KCT0005307 |
Phase 2 Clinical |
Recruiting |
3 |
|
40 |
Dong Sik Jung |
2020-08-12 |
| MITIGATE COVID-19: A clinical trial of icosapent ethyl(VASCEPA) in patients with established atherosclerotic cardiovascular disease who are at elevated risk of experiencing moderate to severe COVID-19 |
Atherosclerosis, Cardiovascular disease, Coronavirus disease 19 infection |
icosapent ethyl alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Amarin Corp plc, Kaiser Permanente |
|
|
|
|
MITIGATE COVID-19 |
Phase Not Applicable |
Status not specified |
0 |
|
1500 |
Dr. Alan S. Go, Dr. Andrew P. Ambrosy, |
2020-08-11 |
| Tenecteplase in Patients With COVID-19 |
Coronavirus disease 19 infection, Respiratory failure |
heparin plus tenecteplase |
Tissue plasminogen activator stimulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Mount Sinai Medical Center |
Genentech Inc |
US |
2020-08-31 |
2021-04-30 |
GCO 20-1764, NCT04505592 |
Phase 2 Clinical |
Not yet recruiting |
1 |
8 Months |
60 |
Denise Balili, MS, Hooman Poor, MD, J Mocco, MD, Lisa Genadry, Sukaina Davdani |
2020-08-12 |
| A Randomized, Controlled, Multicenter, Parallel-Group Phase II Study to Evaluate the Efficacy and Safety of Intramuscular Injections of PLX-PAD for the Treatment of severe COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
PLX stem cell therapy, Pluristem/Cha Bio & Diostech alone |
IL-6 receptor agonist |
|
Pluristem Therapeutics Inc |
|
Germany |
|
|
|
Phase 2 Clinical |
Not yet recruiting |
1 |
|
40 |
|
2020-08-13 |
| A trial to evaluate Organicell Flow in patients with COVID-19 admitted to the ICU |
Coronavirus disease 19 infection |
Organicell Flow alone |
|
|
Organicell Regenerative Medicine |
|
US |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
1 |
|
2020-08-11 |
| A trial to evaluate Organicell Flow in patient with COVID-19 related respiratory impairment and acute kidney injury |
Coronavirus disease 19 infection, Renal injury, Respiratory disease |
Organicell Flow alone |
|
|
Organicell Regenerative Medicine |
|
Georgia |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
1 |
|
2020-08-11 |
| SISCOVID: Follow-up of Respiratory Sequelae of Hospitalized Patients With COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Groupe Hospitalier de la Region de Mulhouse et Sud Alsace |
|
France |
2020-06-10 |
2021-06-30 |
GHR 1052, IDRCB 2020-A01089-30, NCT04505631, SISCOVID |
Phase Not Applicable |
Recruiting |
14 |
12 Months |
100 |
Acya Bizieux, MD, Amélie Leurs, MD, Cécile Carvallo, MD, Cécilia Nocent-Ejnaini, MD, Didier Debieuvre, MD, François Goupil, MD, George-Daniel Calcaianu, MD, Hugues Morel, MD, Jean-Philippe Oster, MD, Johanna Claustre, MD, Laurent Portel, MD, Marie Diesel, Marie-Germaine Legrand, MD, Nadine Paillot, MD, Stéphane Hominal, MD, Stéphanie Romanet, MD |
2020-08-12 |
| A trial to evaluate Organicell Flow in patients with mild to moderate respiratory distress due to COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
Organicell Flow alone |
|
|
Organicell Regenerative Medicine |
|
US |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
1 |
|
2020-08-11 |
| A phase I/IIa clinical study to assess UMSC-01 for the treatment of patients with COVID-19 infection |
Coronavirus disease 19 infection |
UMSC-01 alone |
|
|
Ever Supreme Bio Technology Co Ltd |
|
US |
|
|
ES-CMSC01-C1101 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
|
|
|
2020-08-11 |
| A clinical trial of JAN-101 for the potential treatment of vascular complications in COVID-19 patients |
Coronavirus disease 19 infection, Vascular disease |
JAN-101 alone |
|
|
Cato Holding Ltd, JanOne Inc |
|
US |
|
|
|
Phase Not Applicable |
Planned |
1 |
|
|
Dr. Amol Soin |
2020-08-11 |
| CorKid: CorKid (COVID19/ SARS-CoV-2 seroconversion in kids) |
Coronavirus disease 19 infection |
|
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Universitätskinderklinik im St.-Josef Hospital Klinikum der Ruhr-Universität-Bochum |
German Federal Ministry of Education and Research, Ruhr Universitat Bochum |
Germany |
2020-06-08 |
|
20-6927, CorKid, DRKS00022434 |
Phase Not Applicable |
Recruiting |
3 |
|
3000 |
Corkid Studienteam, Thomas Lücke |
2020-08-12 |
| Role of Famotidine in the Symptomatic Improvement of COVID-19 Patients |
Coronavirus disease 19 infection |
famotidine (Famotac) alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Chattogram General Hospital |
The First Affiliated Hospital of Xi'an Jiaotong University |
Bangladesh |
2020-08-01 |
2020-10-30 |
10000753/980, NCT04504240 |
Phase 3 Clinical |
Recruiting |
2 |
2 Months |
200 |
Abu Taiub Mohammed Mohiuddin Chowdhury, Abu Taiub Mohammed Mohiuddin Chowdhury, MBBS, MD, Aktar Kamal, MD, PhD, H.M. Hamidullah Mehedi, MBBS, FCPS, H.M.Hamidullah Mehedi, H.M.Hamidullah Mehedi, MMBS, FCPS |
2020-08-13 |
| Patients' Experiences in a Medicalized Hotel for COVID-19 Acute Care Support |
Coronavirus disease 19 infection |
|
|
|
Hospital Clinic of Barcelona |
|
Spain |
2020-05-15 |
2020-06-06 |
MEDICALITZED HOTEL COVID-19, NCT04503434 |
Phase Not Applicable |
Completed |
1 |
|
517 |
Carme Hernandez, PhD |
2020-08-12 |
| DenutCOVID: Nutritional Assessment of Hospitalized Patients With COVID-19 |
Coronavirus disease 19 infection, Nutritional disorder |
nutrition testing alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Lille Catholic University |
|
France |
2020-05-25 |
2021-06-30 |
DenutCOVID, NCT04503525, RC-P00100 |
Phase Not Applicable |
Recruiting |
1 |
13 Months |
50 |
Amel Boulafa, Master, Amelie LANSIAUX, MD, PhD, Arnaud CORTET, PhD, Arnaud Cortet, MD |
2020-08-12 |
| A clinical study to assess the safety and efficacy of ANA-001 (niclosamide capsules) as well as its ability to show a clinical improvement in hospitalized patients with COVID-19 |
Coronavirus disease 19 infection |
repurposed niclosamide (oral/capsule, COVID-19), ANA Therapeutics alone |
|
|
ANA Therapeutics |
|
US |
|
|
|
Phase Not Applicable |
Not yet recruiting |
2 |
|
400 |
|
2020-08-14 |
| An observational study on the optimization of hydroxychloroquine dosing for the treatment of patients with COVID-19 |
Coronavirus disease 19 infection |
hydroxychloroquine alone, azithromycin plus hydroxychloroquine |
|
|
University of California San Francisco |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
116 |
|
2020-08-12 |
| Ultrafast Screening of novel coronavirus pneumonia (COVID-19) by Machine Learning Analysis of Exhaled NO |
Coronavirus disease 19 infection, Viral pneumonia |
preliminary screening( Machine Learning Analysis of Exhaled NO ) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Liyuan Hospital |
Shandong University |
China |
2020-03-01 |
2021-06-30 |
ChiCTR2000035342 |
Phase 0 Clinical |
Recruiting |
2 |
16 Months |
|
Jing Ma, Wei-Qiao Deng |
2020-08-11 |
| Covid-19 Messaging to Underserved Communities - Second Experiment |
Coronavirus disease 19 infection |
AMA Acknowledgement Drug Pricing alone, Acknowledgement Racial Injustice AMA alone, Acknowledgement alone, Informational Videos alone, No Racial Inequality Highlighting alone, Racial Inequality Highlighted alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), African Ancestry |
National Bureau of Economic Research Inc |
Harvard University, Massachusetts General Hospital, Stanford University, Yale University |
US |
2020-08-31 |
2021-09-30 |
2029880, NCT04502056 |
Phase Not Applicable |
Not yet recruiting |
1 |
13 Months |
20000 |
Esther Duflo |
2020-08-13 |
| Parent Telehealth Intervention for Children With Autism |
Autism, Coronavirus disease 19 infection |
Responsive training alone, Video feedback alone |
|
Healthy volunteers accepted, Infants (6-23 months), Preschool Children (2-5 yrs) |
Northwestern University |
|
US |
2020-03-06 |
2021-07-31 |
NCT04501588, STU00201708 |
Phase 2 Clinical |
Recruiting |
1 |
16 Months |
40 |
Laura Sudec, MSW, Megan Y Roberts, PhD |
2020-08-13 |
| Western Kenya Integrated COVID-19 Response |
Coronavirus disease 19 infection |
Training clinicians in basic critical care alone, Training of youth, community health assistants and community health workers. alone, management of severe COVID-19 cases alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
SURGICAL SYSTEMS RESEARCH GROUP |
Tropical Institute of Community Health and Development (TICH), Wellcome Trust |
Kenya |
2020-05-18 |
2020-08-19 |
001, NCT04501458 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
200000 |
Neema Kaseje, MD |
2020-08-12 |
| Psychological Symptoms and Families of COVID-19 Patients |
Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder, Psychiatric disorder |
Post-ICU discharge survey and Interview alone, Written Summary of Rounds alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Rush University Medical Center |
|
US |
2020-08-20 |
2021-09-15 |
20071101, NCT04501445 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
100 |
Jared A Greenberg |
2020-08-12 |
| COVID-19 Project ECHO in Nursing Homes |
Coronavirus disease 19 infection |
Project ECHO alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Milton S. Hershey Medical Center |
|
US |
2020-08-31 |
2022-07-31 |
NCT04499391, PCORI NURSING HOMES |
Phase Not Applicable |
Not yet recruiting |
1 |
23 Months |
100 |
Erica Francis, Jennifer Kraschnewski |
2020-08-14 |
| BONSAI: Burnout and Distress prevention With cannabidiol in Front-line Health Care workers dealing with COVID-19 |
Acute stress disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder |
cannabidiol alone, fitness video watching alone, supporting motivational video watching alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
University of Sao Paulo |
|
Brazil |
2020-06-16 |
2020-09-30 |
30504620.4.0000.5440, BONSAI, BONSAI Study, NCT04504877 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
3 Months |
102 |
Jose A. Crippa, MD, PhD, Jose Alexandre de Souza Crippa, Julia C Pacheco, MsC, Julia C. Pacheco, MsC |
2020-08-12 |
| CovAb: COVID-19 Seroprevalence Study in ITM Staff |
Coronavirus disease 19 infection |
Anti-SARS-CoV-2 ELISA (EUROIMMUN) alone, WANTAI SARS-CoV-2 Ab ELISA (WANTAI SARS-CoV-2 Diagnostics) alone |
|
|
Institute of Tropical Medicine, Belgium |
|
Belgium |
2020-08-01 |
2020-09-30 |
CovAb, NCT04503447, SARSCOV2SEROPREVALENCEITMSTAFF |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
430 |
Bart Karl Jacobs, Lut Lynen, Marie Laga, Marjan Van Esbroeck, Marjan Van Esbroeck, MD, Nikki Foqué, Sarah Gils |
2020-08-12 |
| A randomized, placebo-controlled, double-blind, phase II clinical trial to assess CAP-1002 in patients with severe or critical COVID-19 infection |
Coronavirus disease 19 infection |
CAP-1002 alone |
|
|
Capricor Therapeutics Inc |
|
US |
2020-09-30 |
|
|
Phase 2 Clinical |
Planned |
1 |
|
60 |
|
2020-08-10 |
| 300BCG: A study to evaluate BCG vaccine in a group of healthy subjects |
Coronavirus disease 19 infection |
BCG vaccine alone |
|
Healthy volunteers accepted |
Radboud University |
|
Netherlands |
|
|
300BCG |
Phase Not Applicable |
Status not specified |
1 |
|
|
|
2020-08-11 |
| A Randomized, Controlled, Phase IIb Trial to Evaluate Safety and Efficacy of Rivaroxaban |
Coronavirus disease 19 infection |
rivaroxaban alone |
Factor Xa antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Bill & Melinda Gates Medical Research Institute |
|
|
2020-08-31 |
2020-12-31 |
GATES MRI - COD-01-T01-01, NCT04504032 |
Phase 2b Clinical |
Not yet recruiting |
0 |
4 Months |
600 |
Gates MRI, GatesMRI |
2020-08-12 |
| VisVasc COVID-19: Visualizing blood vessel disease in the eye in COVID-19 |
Coronavirus disease 19 infection, Retinopathy, Vascular disease |
fundal photography alone, optical coherence tomography alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
North Bristol NHS Trust |
Southmead Hospital, Wellcome Trust |
UK |
2020-08-06 |
2021-08-05 |
IRAS 286315, ISRCTN59449699, VisVasc COVID-19 |
Phase Not Applicable |
Not yet recruiting |
2 |
12 Months |
30 |
Dr Rice |
2020-08-14 |
| CANCOVID-19: Add on to Azythromycine, Phytomedicine and/or Antimalarial Drug Versus Hydroxychloroquine in Uncomplicated COVID-19 Patients |
Coronavirus disease 19 infection |
Variable regimens including Cospherunate (artesunate + amodiaquine) , azithromycin , phytomedicine tablet (Asen) |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Institute for Research and Development of Medicinal and Food Plants of Guinea |
|
Guinea |
2020-06-01 |
2020-09-30 |
CANCOVID-19, NCT04502342, RDIMFPG |
Phase 2 Clinical |
Recruiting |
1 |
4 Months |
30 |
Mamadou A Baldé |
2020-08-10 |
| A large-scale trial to evaluate Gam-COVID-Vac for the prevention of Covid-19 |
Coronavirus disease 19 infection |
Sputnik V alone |
COVID19 Spike glycoprotein modulator |
|
Gamalei Institute of Epidemiology and Microbiology |
|
|
|
|
|
Phase 3 Clinical |
Planned |
0 |
|
|
|
2020-08-13 |
| Pred-MAKER: Prediction of Major Adverse Kidney Events and Recovery |
Coronavirus disease 19 infection, Renal disease |
KidneyIntelX alone |
|
|
Mount Sinai School of Medicine, Renalytix AI plc |
|
US |
|
|
Pred-MAKER |
Phase Not Applicable |
Status not specified |
1 |
|
|
Dr. Steven Coca |
2020-08-10 |
| MASKeD-COVID: Multicenter Assessment of Survivors for Kidney Disease After COVID-19 |
Coronavirus disease 19 infection, Renal disease, Renal failure |
KidneyIntelX alone |
|
|
Mount Sinai School of Medicine, Renalytix AI plc |
|
US |
2020-08-03 |
|
MASKeD-COVID |
Phase Not Applicable |
Recruiting |
2 |
|
4000 |
F. Perry Wilson, Matthias Kretzler |
2020-08-10 |
| PERSONAL-COVIDBP: Personalised Electronic Record Supported OptimisatioN when ALone for Patients with Hypertension- Pilot Study for Remote Medical Management of Hypertension During the COVID-19 Pandemic |
Coronavirus disease 19 infection, Hypertension |
amlodipine alone |
Calcium channel inhibitor L-type |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Queen Mary University of London |
Technology Strategy Board |
UK |
2020-07-17 |
|
2020-002494-10, PERSONAL-COVIDBP |
Phase 4 Clinical |
Recruiting |
1 |
|
1000 |
Dr David Collier |
2020-08-10 |
| CLiCK Study: A study to look at the safety and success of using Clazakizumab in patients who have kidney disease and COVID-19 |
Coronavirus disease 19 infection |
clazakizumab alone |
IL-6 receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Imperial College London |
Vitaeris Inc |
UK |
2020-07-24 |
|
2020-002476-13, 20HH5958, CLiCK Study |
Phase 2 Clinical |
Recruiting |
1 |
|
20 |
|
2020-08-11 |
| Effects of Tocilizumab and its combination with Vitamin D to treat the increased defensive response in COVID-19 |
Coronavirus disease 19 infection |
tocilizumab (intravenous), Roche/Chugai alone |
IL-6 receptor antagonist, IL-6 receptor modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Universitario de Móstoles |
Servicio Madrileño de Salud (SERMAS) |
Spain |
2020-06-10 |
|
2020-001903-17, HMos-012020 |
Phase 3 Clinical |
Recruiting |
1 |
|
120 |
MEDICAL DIRECTOR |
2020-08-10 |
| An initial study to evaluate the accuracy of NeuCovix for the detection of neutralizing antibodies in patients with COVID-19 infection |
Coronavirus disease 19 infection |
NeuCovix alone |
|
|
Axim Biotechnologies Inc |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
|
|
2020-08-10 |
| Efficacy and safety of Montelukast as add on treatment to the novel coronavirus pneumonia (COVID-19) |
Coronavirus disease 19 infection |
montelukast sodium alone |
Leukotriene D4 antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Porto |
|
Portugal |
2020-07-06 |
|
2020-001747-21, ISPUP2020CT1 |
Phase 4 Clinical |
Recruiting |
1 |
|
160 |
Clinical trials information |
2020-08-10 |
| ARCADIA: A Phase II clinical trial to assess how safe and how effective AZD-1656 is in treating COVID-19 in diabetic patients compared to placebo |
Coronavirus disease 19 infection |
AZD-1656 alone |
Glucokinase stimulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
St George Street Capital |
|
UK |
2020-07-31 |
|
2020-002211-21, ARCADIA, SGS.1656.201 |
Phase 2 Clinical |
Recruiting |
1 |
|
150 |
Clinical Trials |
2020-08-11 |
| SPESELPIS: A Trial of NT-I7 in COVID-19 |
Coronavirus disease 19 infection |
efineptakin alfa alone, standard of care alone |
IL-7 receptor agonist, Interleukin-7 ligand |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
National Institute of Allergy and Infectious Diseases, National Institutes of Health, NeoImmuneTech Inc, University of Nebraska Medical Center |
National Institute of Allergy and Infectious Diseases |
US |
2020-08-31 |
2021-12-31 |
NCT04501796, NIT-116 (SPESELPIS), SPESELPIS, SPESELPIS |
Phase 1 Clinical |
Recruiting |
2 |
16 Months |
30 |
Amy Haberman, Andre Kalil, M.D., M.P.H, Anela Kellogg, Megan Anderson, NgocDiep |
2020-08-10 |
| TICO/ACTIV-3: Therapeutics for Inpatients With COVID-19 |
Coronavirus disease 19 infection |
LY-CoV555 plus remdesivir |
COVID19 Spike glycoprotein modulator, COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Institute of Allergy and Infectious Diseases, National Institutes of Health |
AIDS Clinical Trials Group, Cardiothoracic Surgical Trials Network, Copenhagen University, International Network for Strategic Initiatives in Global HIV Trials (INSIGHT), Medical Research Council, National Centre in HIV Epidemiology and Clinical Research, National Heart Lung and Blood Institute, Prevention and Early Treatment of Acute Lung Injury (PETAL), US Department of Veterans Affairs, Washington D.C. Veterans Affairs Medical Center |
US |
2020-08-04 |
2021-07-31 |
014 / ACTIV-3, NCT04501978, TICO/ACTIV-3 |
Phase 3 Clinical |
Recruiting |
2 |
11 Months |
10000 |
Alan Moskowitz, M.D, Annetine Gelijns, Ph.D, Do not include personal information in email, Jens Lundgren, M.D, Prof. James Neaton, Rachel Ramoni, D.M.D, Sc.D, Taylor Thompson, M.D |
2020-08-11 |
| Effectiveness of gargle and nasal spray with Hydrogen Peroxide as an auxiliary treatment for corona virus |
Coronavirus disease 19 infection |
Hydrogen Peroxide alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universidado de Passo Fundo |
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior |
Brazil |
2020-06-26 |
2020-08-30 |
31752720.1.0000.5342, 4.071.153, RBR-6sx3sz, U1111-1254-2210 |
Phase 1/Phase 2 Clinical |
Recruiting |
1 |
2 Months |
240 |
Henrique Cesca, Marielle Bazzo Di Domênico, Pedro Henrique Corazza |
2020-08-07 |
| Behavior During and After COVID-19-crisis |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Bern University of Applied Sciences |
|
Switzerland |
2020-04-01 |
2022-12-31 |
BFH CORONA, NCT04502108 |
Phase Not Applicable |
Recruiting |
2 |
33 Months |
1000 |
Heiner Baur, Ph.D, Slavko Rogan, Slavko Rogan, Ph.D |
2020-08-11 |
| Study to Evaluate the Efficacy and Safety of Remdesivir (GS-5734) Treatment of Coronavirus Disease 2019 (COVID-19) in an Outpatient Setting |
Coronavirus disease 19 infection |
remdesivir alone |
COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Gilead Sciences Inc |
|
|
2020-09-30 |
2021-01-31 |
2020-003510-12, GS-US-540-9012, NCT04501952 |
Phase 3 Clinical |
Not yet recruiting |
0 |
4 Months |
1230 |
Gilead Clinical Study Information Center, Gilead Study Director |
2020-08-13 |
| PHYTCOVID-19: Phytomedicines Versus Hydroxychloroquine as an Add on Therapy to Azythromycin in Asymptomatic COVID-19 Patients |
Coronavirus disease 19 infection |
azithromycin alone, plant species powder alone, Variable regimens including Quinquina-Stevia , azithromycin , hydroxychloroquine |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Institute for Research and Development of Medicinal and Food Plants of Guinea |
|
Guinea |
2020-06-01 |
2020-09-30 |
IRDPMAG, NCT04501965, PHYTCOVID-19 |
Phase 2 Clinical |
Recruiting |
1 |
4 Months |
231 |
Mamadou A Baldé, Mohamed Cissé, Saliou Sow |
2020-08-14 |
| Short-term Impact of COVID-19 Lockdown on Metabolic Control of Type 2 Diabetes |
Coronavirus disease 19 infection, Non-insulin dependent diabetes |
antidiabetic treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Pisa |
|
Italy |
2020-03-11 |
2020-06-30 |
AS0007, NCT04501991 |
Phase Not Applicable |
Completed |
1 |
3 Months |
114 |
Anna Solini, MD, PhD |
2020-08-11 |
| Effect of finasteride on COVID-19 treatment |
Coronavirus disease 19 infection, Viral pneumonia |
Variable regimens including ceftriaxone , finasteride , hydroxychloroquine |
5-Alpha-reductase inhibitor |
Male, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Qazvin University Of Medical Sciences |
|
Iran |
2020-03-20 |
|
IR.QUMS.REC.1399.016, IRCT20200505047318N1 |
Phase 3 Clinical |
No longer recruiting |
2 |
|
80 |
Abbas Allamy, Dr.Abbas Allami, Dr.Abbas Allamy |
2020-08-10 |
| Impact of Spectacles on Compliance to Mask-wearing Directives |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Of Thrace |
|
Greece |
2020-06-25 |
2020-08-14 |
ES8/TH5/25-06-2020, NCT04501172 |
Phase Not Applicable |
No longer recruiting |
1 |
1 Month |
1214 |
Labiris Georgios, MD, PhD |
2020-08-12 |
| Prospective Study initiated by University Hospital Rostock concerning COVID-19 in mothers, nursery and school teachers of children in Rostock |
Coronavirus disease 19 infection |
biological sampling alone, polymerase chain reaction alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Universitätsmedizin Rostock |
Deutsche Forschungsgemeinschaft (DFG), German Federal Ministry of Education and Research, Land Mecklenburg-Vorpommern |
Germany |
2020-08-10 |
|
A 2020-0090, DRKS00022504 |
Phase Not Applicable |
Recruiting |
1 |
|
600 |
Emil C. Reisinger, Hilte Geerdes-Fenge |
2020-08-10 |
| Evaluating the effect of Ivermectin on COVID-19 patients |
Coronavirus disease 19 infection |
ivermectin alone |
Chloride channel modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ahvaz University of Medical Sciences |
|
Iran |
2020-07-30 |
|
IR.AJUMS.REC.1399.322, IRCT20200404046937N4 |
Phase 2 Clinical |
Recruiting |
2 |
|
60 |
Mehran Varnaseri, Mehran Varnasseri, Mohammad Badavi |
2020-08-10 |
| A clinical study to evaluate the effect of BioTech Life Sciences proprietary formulas on long-term patient symptoms related to COVID-19 Post-Viral Fatigue (long-haulers) and chronic fatigue syndrome |
Chronic fatigue syndrome, Coronavirus disease 19 infection |
proprietary formulas, BioTech Life Sciences alone |
|
|
BioTech Life Sciences |
|
|
|
|
|
Phase Not Applicable |
Recruiting |
0 |
|
|
|
2020-08-07 |
| A phase II clinical trial of VBI-2900 for the potential treatment of SARS-CoV-2 infection |
Coronavirus disease 19 infection |
VBI-2901 alone |
|
|
VBI Vaccines Inc |
|
|
2020-12-31 |
|
|
Phase 2 Clinical |
Planned |
0 |
|
|
|
2020-08-07 |
| Efficacy of Vitamin D Treatment in Pediatric Patients Hospitalized by COVID-19 |
Coronavirus disease 19 infection, Respiratory disease |
cholecalciferol alone |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) |
Coordinacion de Investigacion en Salud |
Hospital General de Mexico, Hospital Infantil de Mexico Federico Gomez |
Mexico |
2020-07-15 |
2021-04-30 |
NCT04502667, R-2020-3603-020 |
Phase 3 Clinical |
Recruiting |
1 |
9 Months |
40 |
Carla Castuera Martinez, Carmen Espinosa-Sotelo, MD, Guadalupe Miranda-Novales, PhD, JESSIE ZURITA-CRUZ, JESSIE ZURITA-CRUZ, PhD, Jessie N ZURITA-Cruz, Jessie ZURITA-CRUZ, Mardia Lopez-Alarcon, PhD, Miguel Angel Villasis-Keever, Miguel Villasis-Keever, PhD |
2020-08-10 |
| Fiberoptic Bronchoscopy and Bronchoalveolar Lavage in Critically Ill Ventilated Patients |
Coronavirus disease 19 infection, Respiratory disease |
PulmoVista 500 (Draeger) alone, bronchoalveolar lavage analysis alone, electrical impedance tomography alone, fiberoptic bronchoscopy alone, multiple arterial blood gas test alone, realtime thoracic impedance analysis alone, sodium chloride alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Erasme Hospital |
|
Belgium |
2020-08-06 |
2020-09-30 |
NCT04502368, P2020/375, SRB2020-289 |
Phase Not Applicable |
Recruiting |
3 |
1 Month |
15 |
Francesco Ricottilli,, Francesco Ricottilli, MD, Leda Nobile, MD |
2020-08-11 |
| ACTIV-2: A Phase II clinical trial to evaluate the safety and efficacy of LY-CoV555 for COVID-19 |
Coronavirus disease 19 infection |
LY-CoV555 alone |
COVID19 Spike glycoprotein modulator |
|
National Institute of Allergy and Infectious Diseases, National Institutes of Health |
|
US |
|
|
ACTIV-2 |
Phase 2 Clinical |
Recruiting |
1 |
|
|
Davey Smith, David Wohl, Kara W. Chew |
2020-08-11 |
| One-year Cardiac Follow-up of Patients With COVID-19 Pneumonia |
Cardiovascular disease, Coronavirus disease 19 infection, Viral pneumonia |
clinical test alone, instrumental test alone, laboratory diagnostics tests alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Federal Noe G Bjudzhetnoe Uchrezhdenie Nii Onkologii Sib Otdel Rossijskoj Akademii Med Nauk Fgbu Nii |
|
Russian Federation |
2020-07-19 |
2021-12-31 |
NCT04501822, TCRC-COVID |
Phase Not Applicable |
Recruiting |
1 |
17 Months |
380 |
Elena Yaroslavskaya, PhD, Ivan Bessonov, PhD |
2020-08-10 |
| Inova-CCP: Open-label Treatment of Severe Coronavirus Disease 2019 (COVID-19) With Convalescent Plasma |
Coronavirus disease 19 infection |
COVID-19 convalescent plasma (CCP) transfusion alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Inova Health Care Services |
|
US |
2020-06-06 |
2021-12-31 |
INOVA COVID-19 CCP, Inova-CCP, NCT04502472 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
18 Months |
200 |
Anne Brown, M.D., Anne W Brown, MD, Edwinia Battle, BSN, Merte Lemma-Woldehanna, BS, Merte Lemme-Woldehanna, BS |
2020-08-10 |
| Opaganib-RHB: Treatment of COVID-19 With Opaganib in Patients With Pneumonia Requiring Oxygen |
Coronavirus disease 19 infection, Viral pneumonia |
opaganib alone |
Dihydroceramide delta 4 desaturase inhibitor, Sphingosine kinase 2 inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
RedHill Biopharma Ltd |
|
Israel |
2020-08-31 |
2021-06-30 |
ABC-112, NCT04502069, Opaganib-RHB |
Phase 1/Phase 2 Clinical |
Terminated |
1 |
10 Months |
|
Mark L Levitt, MD |
2020-08-12 |
| A clinical trial of cannabinoid Sol-gel for the treatment of covid-19 |
Coronavirus disease 19 infection |
cannabinoid Sol-gel alone |
|
|
PreveCeutical Medical Inc, Veristat, Inc. |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-08-07 |
| Exhaled Breath Particles as a Clinical Indicator for Lung Injury and Acute Respiratory Distress Syndrome (ARDS) |
Acute lung injury, Coronavirus disease 19 infection, Lung infection, Respiratory distress syndrome |
exhaled breath particles PCR test alone, real time particle flow rate prediction test alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Skåne University Hospital |
|
Sweden |
2020-05-01 |
2024-05-01 |
NCT04503057, PEX ARDS |
Phase Not Applicable |
Recruiting |
1 |
48 Months |
300 |
Leif Pierre, PhD, Sandra Lindstedt Ingemansson, MD, PhD |
2020-08-10 |
| CODIS: Cardiac Rehabilitation and Ongoing Physical Activity During COVID-19 |
Cardiovascular disease, Coronavirus disease 19 infection |
cycle ergometry test alone, semi-structured qualitative interview alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ludwig Boltzmann Institute for Digital Health and Prevention |
Paracelsus Medical University |
Austria |
2020-07-14 |
2020-12-31 |
23_CODIS, CODIS, NCT04501432 |
Phase Not Applicable |
Recruiting |
1 |
5 Months |
40 |
Josef Niebauer, Prof.Dr.Dr., Mahdi Sareban, Dr. Dr. med., Mahdi Sareban, Dr.Dr.med., Stefan T Kulnik, PhD MRes |
2020-08-10 |
| Studying the progression and the consequences of the new Coronavirus in Brazil |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fundacao Oswaldo Cruz (Fiocruz) |
Conselho Nacional de Desenvolvimento Cientifico e Tecnologico - CNPq |
Brazil |
2020-08-03 |
|
32874720.8.1001.5262, 4.148.652, RBR-8hmb2r, U1111-1255-9610 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1200 |
André Siqueira, Giselle Duarte, José Moreira |
2020-08-13 |
| Intravenous Immunoglobulin (IVIG, Bioven) Efficacy Assess for COVID-19/SARS-CoV-2 Severe Pneumonia Complex Treatment |
Coronavirus disease 19 infection, Lung inflammation, Respiratory distress syndrome, Respiratory failure, Respiratory tract infection, Viral pneumonia |
Bioven (Biopharma Plasma LLC) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
BIOPHARMA PLASMA LLC |
|
Ukraine |
2020-05-07 |
2020-09-30 |
2020-BV-BP, NCT04500067 |
Phase 3 Clinical |
Recruiting |
8 |
4 Months |
76 |
Anatolii M Deyneka, MD, Andrii R Rybakov, MD, Igor P Bernik, MD, Iryna V Kobylyan, MD, Kateryna Yu Romanchuk, MD, Khrystyna V Lewandowska, MD, Larisa V Moroz, MD, Lilia Ya Romaniv, MD, Liliya B Kurilyak, MD, Ludmila K Boshkova, MD, Maryana V Gurkivska, MD, Mikhail G Kuzyuk, MD, Natalia B Zhevoronko, MD, Nataliya O Ivanchenko, MD, Oksana I Paraschuk, MD, Oksana M Mazur, MD, Oksana Ya Kadubets', MD, Oleg K Yakovenko, MD, Olena Ya Kobrynska, MD, Olga V Pronina, MD, Pavlo A Gashchishin, MD, Roman M Fishchuk, MD, Ruslan V Mazur, MD, Sergii L Zanozdra, MD, Sergii O Solyarik, MD, Svitlana Y Lavryukova, MD, Taisiya V Vzhetson, MD, Tamila I Aleksanyan, MD, Vasyil S Kopcha, MD, Prof., Viktor P Tokarev, MD, Vitalii A Lukiyanchuk, MD, Yaroslav G Zhebelenko, Ph.D., MD |
2020-08-10 |
| A clinical trial of Interleukin-6 inhibitorsfor the effective treatment of Coronavirus disease 19 infection |
Coronavirus disease 19 infection |
sarilumab plus tocilizumab (intravenous), Roche/Chugai |
IL-6 receptor antagonist, IL-6 receptor modulator |
|
Boston Medical Center Corp, ROCHE/CHUGAI Pharma AG |
|
US |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
255 |
|
2020-08-14 |
| Clinical outcome and psychological impact Covid-19 |
Coronavirus disease 19 infection |
|
|
|
Hospital Sungai Buloh |
|
Malaysia |
2020-08-05 |
2021-08-05 |
NMRR-20-1701-55822 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
|
Dr NORASHIKIN BT. ABDUL FUAD, Dr Syarifah Nurul Ain Bt Syed Badaruddin, Professor Dr Zaleha Abdullah Mahdy |
2020-08-10 |
| A trial of NTR-441 to treat hyperinflammation and thrombosis in COVID-19 patients, including those with Acute Respiratory Distress Syndrome (ARDS) |
Coronavirus disease 19 infection, Inflammatory disease, Respiratory distress syndrome, Thrombosis |
NTR-441 alone |
Deoxyribonuclease gamma stimulator |
|
Neutrolis Therapeutics Inc |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-08-06 |
| Mental Health Screening during COVID-19 Pandemic among School Teachers in Kerian District |
Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression, Psychiatric disorder |
|
|
|
QUEST INTERNATIONAL UNIVERSITY PERAK |
|
Malaysia |
2020-10-01 |
2020-12-31 |
55999, NMRR-20-1700-55999 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
|
Tan Sing Ying |
2020-08-10 |
| SCOT:REACH-HF: Understanding delivery of a new home rehabilitation programme for people with heart failure and their caregivers in Scotland |
Cardiac failure, Coronavirus disease 19 infection |
home cardiac rehabilitation program alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
NHS Greater Glasgow and Clyde |
Heart Research UK |
UK |
2020-02-01 |
2021-08-31 |
IRAS 276172, ISRCTN53784122, SCOT:REACH-HF |
Phase Not Applicable |
Not yet recruiting |
5 |
19 Months |
280 |
Dr Purcell, Prof Rod Taylor |
2020-08-12 |
| DeSACCoS: Detection of SARS-CoV-2 Among Convalescent COVID-19 Patients Using Saliva |
Coronavirus disease 19 infection |
|
|
|
HOSPITAL SIBU |
|
Malaysia |
2020-08-30 |
2021-08-31 |
DeSACCoS, NMRR-20-1684-56008 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
|
Dr Jeffrey Lee Soon Yit, Dr. Toh Teck Hock |
2020-08-07 |
| Impact of lockdown for COVID-19 pandemic towards glycemic control in paediatric diabetic patients |
Coronavirus disease 19 infection, Diabetes mellitus, Insulin dependent diabetes, Non-insulin dependent diabetes |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Putrajaya Hospital |
|
Malaysia |
2020-08-17 |
2020-12-31 |
55949, NMRR-20-1678-55949 |
Phase Not Applicable |
Not yet recruiting |
1 |
4 Months |
80 |
Dr Cheng Hooi Peng |
2020-08-07 |
| Longitudinal COVID-19 Study |
Coronavirus disease 19 infection |
|
|
|
National Institutes of Health Malaysia |
Ministry of Health, Malaysia |
Malaysia |
2020-08-17 |
2022-07-30 |
NMRR-20-1676-55108 |
Phase Not Applicable |
Recruiting |
1 |
23 Months |
|
Dr MASITA BINTI ARIP, Dr Rafiza binti Shaharudin |
2020-08-07 |
| Longitudinal study of long-term immune response to SARS-CoV-2 in COVID-19 recovered patients |
Coronavirus disease 19 infection |
|
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tropical Infectious Diseases Research & Education Centre |
|
Malaysia |
2020-09-01 |
2022-08-31 |
NMRR-20-1669-55712 |
Phase Not Applicable |
Not yet recruiting |
1 |
24 Months |
|
Prof. Sazaly Abu Bakar |
2020-08-07 |
| Sickness absence in NHS staff during the time of COVID-19 |
Coronavirus disease 19 infection, Psychiatric disorder |
electronic staff records alone |
|
Healthy volunteers accepted |
Imperial College London |
Colt Foundation |
UK |
2020-08-01 |
2021-03-01 |
IRAS 284146, ISRCTN36352994 |
Phase Not Applicable |
No longer recruiting |
1 |
7 Months |
800000 |
Prof Paul Cullinan |
2020-08-12 |
| Identification of inflammation-related gene polymorphisms associated with the severity of COVID-19 |
Coronavirus disease 19 infection |
|
|
|
Tropical Infectious Diseases Research & Education Centre |
|
Malaysia |
2020-09-01 |
2022-08-31 |
55710, NMRR-20-1668-55710 |
Phase Not Applicable |
Not yet recruiting |
1 |
24 Months |
|
Prof. Sazaly Abu Bakar |
2020-08-07 |
| A Phase I trial of recombinant bivalent second-generation adenovirus (hAd5) vector-delivered SARS-CoV-2 S + N protein vaccine in healthy volunteers |
Coronavirus disease 19 infection |
recombinant bivalent second-generation adenovirus (hAd5) vector-delivered SARS-CoV-2 S + N protein vaccine (subcutaneous, COVID-19), ImmunityBio alone |
COVID19 Spike glycoprotein modulator, COVID19 nucleoprotein modulator |
Healthy volunteers accepted |
ImmunityBio Inc |
|
US |
|
|
|
Phase 1 Clinical |
Planned |
1 |
|
|
|
2020-08-11 |
| IKN COVID-19 Task Force Strategies |
Coronavirus disease 19 infection |
|
|
|
National Cancer Institute - Malaysia |
|
Malaysia |
2020-08-10 |
2021-02-19 |
NMRR-20-1665-56009 |
Phase Not Applicable |
Status not specified |
1 |
6 Months |
|
Dr Sarah Pang Hui Li, Miss Siti Fatimah Zahra binti Mohd Anuar |
2020-08-07 |
| COVID-19 Sarawak |
Coronavirus disease 19 infection |
|
|
|
Sarawak General Hospital |
|
Malaysia |
2020-08-03 |
2021-07-31 |
NMRR-20-1656-55896 |
Phase Not Applicable |
Not yet recruiting |
1 |
11 Months |
|
Dr TONNII SIA LOONG LOONG |
2020-08-07 |
| Use of Herbal Medicine like Tulasi,Amruth(Giloy), Turmeric,Ashwagandha for Improving the Immunity among Health care workers |
Coronavirus disease 19 infection |
Variable regimens including Amruth tablet , Shakthi drops , TulsiArka , Turmeric Plus tablet |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Sriveda Sattva PvtLtd |
|
India |
2020-08-15 |
|
CTRI/2020/08/027009 |
Phase 4 Clinical |
Not yet recruiting |
1 |
|
100 |
Dr C R Jayanthi, Dr M Ravi Kumar Reddy |
2020-08-07 |
| STANCE: COVID-19 Pandemic: A situational analysis on clinic appointment system in the New Normal within the Malaysian Healthcare System |
Coronavirus disease 19 infection |
|
|
|
Clinical Research Malaysia |
|
Malaysia |
2020-07-31 |
2020-12-31 |
55650, NMRR-20-1654-55650, STANCE |
Phase Not Applicable |
Not yet recruiting |
1 |
5 Months |
|
Mr. HING YEE LIANG |
2020-08-07 |
| A clinical trial of humanized neutralizing nano-antibodies (nanobody-based technology, COVID-19), Beroni Group/Tianjin University for the potential treatment of COVID-19 infection |
Coronavirus disease 19 infection |
humanized neutralizing nano-antibodies (nanobody-based technology, COVID-19), Beroni Group/Tianjin University alone |
COVID19 Spike glycoprotein inhibitor |
|
Beroni Group Ltd |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-08-06 |
| Well-Being and Health-Related Quality of Life in Cancer Patients and Survivors During the COVID-19 Pandemic |
Anxiety disorder, Coronavirus disease 19 infection, Depression, Psychiatric disorder |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
MD Anderson Cancer Center |
National Cancer Institute |
US |
2020-06-11 |
2021-07-01 |
2020-0473, NCI-2020-04604, NCT04500600 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
50000 |
Lorenzo Cohen |
2020-08-06 |
| RCS-AYUSH: Retrospective cohort study in COVID-19 recovered patients |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Central Council for Research in Homoeopathy |
|
India |
2020-08-14 |
|
CTRI/2020/08/027000, RCS-AYUSH |
Phase Not Applicable |
Recruiting |
1 |
|
5000 |
Dr Anil Khurana, Dr Anupriya, Dr Debadatta Nayak |
2020-08-07 |
| Advantage of Artificial Intelligence to detect COVID 19 using Chest X-Ray |
Coronavirus disease 19 infection |
|
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Nirma University |
|
India |
2020-08-17 |
|
CTRI/2020/08/027008 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1000 |
Dr Asutosh N Dave |
2020-08-07 |
| An interventional study to access the effect of Ayurvedic medicine in positive cases of COVID-19 |
Coronavirus disease 19 infection |
SEM-20 alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Ministry of Ayush |
|
India |
2020-07-31 |
|
CTRI/2020/08/027007 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
200 |
Dr Abhishek Bhattacharjee, Prof Dr P K Goswami |
2020-08-06 |
| Elderly Patients and COVID-19 Infection: a Cohort of Fifty Patients > 90 Years of Age |
Coronavirus disease 19 infection |
|
|
Elderly Adults (80 and over) |
Brugmann University Hospital |
|
Belgium |
2020-06-09 |
2020-12-31 |
CHUB-COVID-19-90+, NCT04499300 |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
50 |
Murielle Surquin, Sophie Levy, Tracy Vandergraesen, MD |
2020-08-10 |
| ZIMCOV: Investigation of effect of homoeopathic remedy as add on therapy to standard of care (regular treatment) in adult patients with moderate to severe COVID-19 |
Coronavirus disease 19 infection |
Zincum muriaticum alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Homoeocon Foundation |
|
India |
2020-08-12 |
|
CTRI/2020/08/027005, ZIMCOV |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
96 |
Dr Anil Habbu, Dr Anil Khurana |
2020-08-06 |
| SIFRA-CBE: Evaluate the Efficacy of Siddha Treatment in Patients with Novel Coronavirus Infectious Disease (COVID-19) |
Coronavirus disease 19 infection |
Adathodai manapagu alone, Mahasudarsan chooranam alone, Maldevi chendooram alone, Nochi kudineer chooranam alone, Omatheeneeer alone, Siddha Medicine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Indian Medicine and Homoeopathy |
Government Medical College and ESI Hospital |
India |
2020-08-10 |
|
CTRI/2020/08/026999, SIFRA-CBE |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
100 |
Dr Salai Karthikaiyan, Dr Shanmugam MD SIDDHA |
2020-08-07 |
| Association of cardiac markers with severity of covid 19 |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Postgraduate Institute of Medical Education and Research |
|
India |
2020-08-20 |
|
CTRI/2020/08/027001 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
70 |
Sunder Lal Negi |
2020-08-07 |
| Study of changes in levels of certain blood parameters in covid-19 patients |
Coronavirus disease 19 infection |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Gujarat Cancer Society Medical college hospital and research centre |
|
India |
2020-08-14 |
|
CTRI/2020/08/026981 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1000 |
Dr Utsav Parmar |
2020-08-08 |
| Sofosbuvir + Ledipasvir and Nitazoxanide for Treatment of COVID-19 |
Coronavirus disease 19 infection, Respiratory disorder, Respiratory failure, Viral pneumonia |
nitazoxanide alone, sofosbuvir + ledipasvir alone, standard care alone |
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Assiut University |
Helwan University |
Egypt |
2020-07-15 |
2020-12-30 |
COVID-19 TREATMENT, NCT04498936 |
Phase 4 Clinical |
Recruiting |
2 |
5 Months |
240 |
Haidi K Ramadan, PhD, Mohamed El Kassas, PhD, Mohamed El kassas, Mohammed A Medhat, PhD, Mohammed Medhat |
2020-08-08 |
| Effect Ayurveda decoctions, tablet and Panchagavya on COVID 19 |
Coronavirus disease 19 infection |
Variable regimens including Fresh zinger juice , Gojihvadi Kwath , Sanjeevani Vati , honey Pancha Gavya Ghrit Granules , milk Shunthi (Dry Ginger powder) |
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Rashtriya Kamdhenu Aayog |
|
India |
2020-08-10 |
|
CTRI/2020/08/026980 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
180 |
Parameswarappa Byadgi |
2020-08-07 |
| An FDA compassionate use program of PSC-04 (Calidi Biotherapeutics Inc)for the treatment of covid-19 |
Coronavirus disease 19 infection |
PSC-04 (Calidi Biotherapeutics Inc) alone |
|
|
Calidi Biotherapeutics Inc, Personalized Stem Cells Inc |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-08-06 |
| A Phase II clinical trial of PSC-04 (Calidi Biotherapeutics Inc)for the treatment of covid-19 |
Coronavirus disease 19 infection |
PSC-04 (Calidi Biotherapeutics Inc) alone |
|
|
Calidi Biotherapeutics Inc, Personalized Stem Cells Inc |
|
|
|
|
|
Phase 2 Clinical |
Planned |
0 |
|
|
|
2020-08-06 |
| The MINDS study: Youth experiences during COVID-19 pandemic |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs) |
Melaka Manipal Medical College, India |
|
India |
2020-08-14 |
|
CTRI/2020/08/026998, The MINDS study |
Phase Not Applicable |
Not yet recruiting |
1 |
|
540 |
Varalakshmi Chandra Sekaran |
2020-08-06 |
| TIP: Talking in primary care: testing the impact of online training in empathy and optimism for healthcare professionals |
Coronavirus disease 19 infection, Osteoarthritis |
continue normal practice alone, online training alone |
|
Healthy volunteers accepted |
University Of Southampton |
National Institute for Health Research (NIHR) |
UK |
2019-12-02 |
2021-03-31 |
CPMS 43793, ISRCTN21215037, TIP |
Phase Not Applicable |
Recruiting |
1 |
15 Months |
280 |
Dr Felicity Bishop, Mrs Broomfield |
2020-08-08 |
| GERAS Frailty Rehabilitation at Home During COVID-19 |
Coronavirus disease 19 infection |
Medication Review alone, Senior Isolation Prevention Partnership (SSIPP) program alone, multi-modal frailty rehabilitation alone, physiotherapy alone, protein supplement (protein + beta-hydroxy beta-methylbutyrate) alone, virtual nutrition consult alone |
|
Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
McMaster University |
|
Canada |
2020-09-30 |
2021-05-31 |
11408, NCT04500366 |
Phase Not Applicable |
Not yet recruiting |
1 |
8 Months |
70 |
Alexandra Papaioannou, MD, MSc, Sherri Smith |
2020-08-08 |
| Assessment of safety and efficacy of Kabasura kudineer in mild to moderate COVID-19 |
Coronavirus disease 19 infection |
Kabasura kudineer alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Chettinad Hospital And Research Institute |
|
India |
2020-08-14 |
|
CTRI/2020/08/026985 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
126 |
Dr Ruckmani A, Dr Vivek Valliappan |
2020-08-08 |
| Effectiveness of Ayurvedic Formulation for COVID 19 |
Coronavirus disease 19 infection |
YASH-T decoction alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Nepal Health Research Council |
|
India |
2020-08-19 |
|
CTRI/2020/08/026978 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Dr Pradip Gyanwali, Shristi Karki |
2020-08-07 |
| OPTYC: Online post-traumatic stress disorder treatment for young people and their carers |
Coronavirus disease 19 infection, Post traumatic stress disorder |
Internet-delivered Cognitive Therapy alone |
|
Children (6-12 yrs), Adolescents (13-17 yrs) |
South London and Maudsley NHS Foundation Trust |
Medical Research Council |
UK |
2017-12-01 |
2022-02-26 |
IRAS 262807, CPMS 42768, ISRCTN16876240, OPTYC |
Phase Not Applicable |
Recruiting |
4 |
50 Months |
34 |
Dr Smith |
2020-08-08 |
| CPIT III: The smoking cessation in pregnancy incentives trial |
Coronavirus disease 19 infection, Nicotine dependence |
face to face counselling alone, £400 of shopping vouchers alone |
|
Female, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
NHS Greater Glasgow and Clyde |
Cancer Research UK, Chief Scientist Office, Northern Ireland Chest Heart & Stroke, Public Health Agency, Scottish Cot Death Trust, The Lullaby Trust |
UK |
2017-09-01 |
2021-02-28 |
36323, CPIT III, ISRCTN15236311 |
Phase 3 Clinical |
No longer recruiting |
3 |
42 Months |
940 |
Prof MTappin |
2020-08-12 |
| Comparison of two online learning method of resuscitation training |
Cardiac arrest, Coronavirus disease 19 infection |
Flexible online learning alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
All India Institute of Medical Sciences |
|
India |
2020-08-10 |
|
CTRI/2020/08/026977 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
20 |
Poonam Joshi |
2020-08-07 |
| OTC AND COVID19: Over-the-counter Medications And COVID-19 |
Coronavirus disease 19 infection |
|
|
|
University of Alberta |
|
Canada |
2020-07-23 |
2023-03-31 |
NCT04500639, OTC AND COVID19, PRO00100243 |
Phase Not Applicable |
Recruiting |
1 |
32 Months |
14000 |
Scot H Simpson, PharmD, MSc, Scot Simpson, PharmD, MSc |
2020-08-10 |
| Evaluation of coronavirus self-isolation interventions |
Coronavirus disease 19 infection |
Call only alone, SMS only alone, SMS plus call alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Health Service |
Department of Health and Social Care |
UK |
2020-07-01 |
2020-09-30 |
ISRCTN13455972, TP_2020065 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
10000 |
Ms Clare Delargy, Ms Hannah Burd |
2020-08-08 |
| An observational study of effect of positioning on either side on oxygen level in corona patient |
Coronavirus disease 19 infection |
lateral positioning alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
New Civil Hospital, Surat |
|
India |
2020-08-09 |
|
CTRI/2020/08/026964 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
167 |
Dr Sunaina patel |
2020-08-07 |
| POCUS: Point of care ultrasound study in patients with respiratory illness during COVID-19 |
Coronavirus disease 19 infection, Respiratory tract infection |
Lung ultrasound alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kasturba Medical College and Hospital |
|
India |
2020-08-17 |
|
CTRI/2020/08/026983, POCUS |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Dr Sanjan |
2020-08-07 |
| Tomographic Findings in COVID-19 and Influenza H1N1 |
Coronavirus disease 19 infection, Influenza virus A infection, Viral pneumonia |
pulmonary tomography alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universidad De Guanajuato |
University Medical Center Groningen |
Netherlands, Mexico |
2020-08-15 |
2022-04-30 |
F-2020-1008-038, NCT04499378 |
Phase Not Applicable |
Not yet recruiting |
2 |
20 Months |
200 |
Jaime D Mondragon, M.D., Omar Jiménez-Zarazúa, M.D. |
2020-08-08 |
| Dexamethasone Versus Methylprednisolone for the Treatment of Patients With ARDS Caused by COVID-19 |
Adult respiratory distress syndrome, Coronavirus disease 19 infection |
dexamethasone alone, methylprednisolone alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Chattogram General Hospital |
Xi' An Medical University |
Bangladesh |
2020-08-02 |
2020-11-30 |
10000753, NCT04499313 |
Phase 3 Clinical |
Recruiting |
2 |
3 Months |
60 |
Abu Taiub Mohammed Mohiuddin Chowdhury, MBBS, MD, Akter Kamal, MBBS, MD, PhD, Akter Kamal, MD, PhD, He Shuixiang, MD, PhD, Shubhashis Talukder, Shubhashis Talukder, MBBS, DO |
2020-08-12 |
| Incubation period of COVID-19 cases admitted in North Kerala, India |
Coronavirus disease 19 infection |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Government Medical College Kannur |
|
India |
2020-09-01 |
|
CTRI/2020/08/026962 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
30 |
Anitha S S |
2020-08-07 |
| MtS Dems: HF4Y: Research demonstration projects in youth homelessness |
Coronavirus disease 19 infection |
Housing First For Youth alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
A Way Home Canada |
Employment Skills Development Canada |
Canada |
2017-08-01 |
2021-03-31 |
1441994, ISRCTN10505930, MtS Dems: HF4Y |
Phase Not Applicable |
No longer recruiting |
2 |
44 Months |
140 |
Dr Stephen Gaetz, Ms MacDonald |
2020-08-06 |
| Evaluation of Knowledge, Attitude and Practice (KAP) of Pharmacists towards novel coronavirus pneumonia (COVID-19): A Cross-Sectional Study |
Coronavirus disease 19 infection, Viral pneumonia |
Online questionnaire alone |
|
|
Peking University Third Hospital |
|
China |
2020-07-23 |
2021-07-22 |
ChiCTR2000035213 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
480 |
Rongsheng ZHAO, Zaiwei SONG |
2020-08-11 |
| Mental Health Status and Related Factors Among Physical Medicine And Rehabilitation Physicians in the COVID-19 Pandemic |
Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression, Insomnia |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Dokuz Eylul University |
|
Turkey |
2020-06-27 |
2020-10-01 |
NCT04500652, PMRMENTALCOVID |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
310 |
Banu Dilek |
2020-08-07 |
| Hyperbaric Versus Normobaric Oxygen Therapy for COVID-19 Patients |
Coronavirus disease 19 infection, Viral pneumonia |
hyperbaric oxygen alone, usual treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ottawa Hospital Research Institute |
Climate Foundation |
Canada |
2020-08-31 |
2022-08-31 |
NCT04500626, OHRI-HBOT-001 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
24 Months |
234 |
Joseph Burns, MSc, Sylvain Boet, MD, PhD |
2020-08-13 |
| ISARIC WHO CCP-UK: Clinical characterization protocol for severe emerging infection |
Coronavirus disease 19 infection, Infectious disease |
routine clinical samples alone |
|
|
University of Oxford |
Medical Research Council, NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, National Institute for Health Research (NIHR), SPRINT-SARI NIHR Health Protection Research Unit (HPRU) in Respiratory Infection, Wellcome Trust |
UK |
2013-03-12 |
2023-02-28 |
IRAS 126600, CPMS 14152, ISARIC WHO CCP-UK, ISRCTN66726260 |
Phase Not Applicable |
Recruiting |
2 |
119 Months |
100 |
Ms Hayley Hardwick, Prof Semple |
2020-08-12 |
| Evaluation of herbal compound containing Anacyclus pyrethrum, Senna, Ferrula asafoetida and Terminalia chebula in COVID19 |
Coronavirus disease 19 infection |
Variable regimens including Anacyclus pyrethrum , Chloroquine phosphate , Ferrula asafoetida , Hydroxychloroquine , Senna , Terminalia chebula |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tabriz University of Medical Sciences |
|
Iran |
2020-07-31 |
2020-09-21 |
IR.TBZMED.REC.1399.126, IRCT20200522047545N1 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
1 Month |
200 |
Mojtaba Varshouchi Fard, Ramin Mohammadzadeh |
2020-08-08 |
| A Study on Prevalence, Protection and Recovery From COVID-19 in Seasoned Yoga Practitioners in Comparison to Age and Gender Matched Controls |
Acute stress disorder, Coronavirus disease 19 infection, Fever, Respiratory disease |
Inner Engineering Completion (Shambhavi Mahamudra kriya) alone, Inner Engineering Online alone, Shakthi Chalana Kriya alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Beth Israel Deaconess Medical Center |
|
US |
2020-05-22 |
2020-12-31 |
2020P000433, NCT04498442 |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
30000 |
Balachundhar Subramaniam, MD, MPH |
2020-08-11 |
| To Evaluate Safety and Efficacy of EC-18 in COVID-19 Infection to Pneumonia |
Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia |
mosedipimod alone |
CCL26 gene inhibitor, TLR modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Enzychem Lifesciences Corp |
|
South Korea |
2020-05-28 |
2022-05-31 |
EC-18-C201, NCT04500132 |
Phase 2 Clinical |
Recruiting |
1 |
24 Months |
60 |
Enzychem Lifescience, Hyewon Jeong |
2020-08-10 |
| A phase III trial to evaluate Metablok for the prevention of organ inflammation known to trigger acute respiratory distress syndrome (ARDS) and acute kidney injury (AKI) in patients infected with SARS-CoV-2 (COVID-19) |
Coronavirus disease 19 infection, Inflammatory disease, Renal injury, Respiratory distress syndrome |
Metablok alone |
Dehydropeptidase-1 modulator |
|
Arch Biopartners Inc |
|
|
|
|
|
Phase 3 Clinical |
Planned |
0 |
|
|
|
2020-08-06 |
| COVEN: Mechanical Ventilation Strategy for Coronavirus Disease 2019 (COVID-19) |
Coronavirus disease 19 infection, Lung injury, Respiratory distress syndrome |
electrical impedance tomography alone, pressure-controlled ventilation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo |
InCor Heart Institute |
Brazil |
2020-05-08 |
2021-12-01 |
CAAE: 30938720800000068, COVEN, NCT04497454 |
Phase Not Applicable |
Recruiting |
1 |
18 Months |
128 |
Eduardo LV Costa, Eduardo LV Costa, PhD, Maria AM Nakamura, Maria AM Nakamura, PhD |
2020-08-07 |
| Novel Coronavirus infection among health workers |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
State of Parana/Health Department of Parana |
|
Brazil |
2020-07-01 |
2021-07-01 |
33697720.0.0000.0107, 4,112,388, RBR-7nky44, U1111-1255-6093 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
703 |
Lirane Elize Ferreto |
2020-08-08 |
| A phase III human trial of Oxford vaccine by serum institute of India |
Coronavirus disease 19 infection |
Oxford vaccine alone |
|
|
Serum Institute of India Ltd |
|
India |
|
|
|
Phase 3 Clinical |
Planned |
1 |
|
1600 |
|
2020-08-06 |
| A phase II trial in India for the covid-19 vaccine candidate developed by University of Oxford |
Coronavirus disease 19 infection |
Oxford vaccine alone |
|
Healthy volunteers accepted |
Serum Institute of India Ltd |
|
India |
|
|
|
Phase 2 Clinical |
Planned |
1 |
|
1600 |
|
2020-08-06 |
| Pilot Study of Video and Telephone Primary Care Visits |
Coronavirus disease 19 infection |
Telemedicine-Internet-connected computer tablet alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Johns Hopkins University |
|
US |
2020-09-01 |
2023-04-01 |
IRB00257994, NCT04496713 |
Phase Not Applicable |
Not yet recruiting |
1 |
31 Months |
200 |
Casey Overby Taylor, PhD, Jeremy A Epstein, MD |
2020-08-14 |
| The Effect of Aromatherapy on COVID-19-induced Anxiety |
Anxiety disorder, Coronavirus disease 19 infection |
Essential Oil Blend inhalation alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Franklin School of Integrative Health Sciences |
|
US |
2020-08-01 |
2021-04-30 |
20-7-5600, NCT04495842 |
Phase Not Applicable |
Not yet recruiting |
1 |
9 Months |
65 |
Jessie Hawkins, PhD, PI |
2020-08-10 |
| Augmented CBGT for Perinatal Anxiety During a Global Pandemic (COVID-19) |
Anxiety disorder, Coronavirus disease 19 infection |
Cognitive Behavioural Group Therapy alone |
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
St Josephs Healthcare Hamilton |
|
|
2020-08-10 |
2022-08-01 |
CBT-COVID, NCT04495803 |
Phase Not Applicable |
Not yet recruiting |
0 |
23 Months |
120 |
Sheryl Green, PhD, CPsych |
2020-08-10 |
| Mitigating Suicide Risk With Single Session 'Brief Skills for Safer Living' |
Coronavirus disease 19 infection, Suicide |
Brief Skills for Safer Living alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
St Michaels Hospital |
|
Canada |
2020-08-31 |
2021-08-31 |
BSL-01, NCT04495543 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
75 |
Aleksandra Lalovic, PhD, Michael Morton, HBSc, Sakina Rizvi, PhD, Sidney H Kennedy, MD, Yvonne Bergmans, PhD |
2020-08-10 |
| Co_Coping: Coping With 2020 - No Health Without Mental Health |
Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Psychiatric disorder |
Intensive Co-mestring alone, Ordinary Co-mestring alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Haukeland University Hospital |
|
Norway |
2020-04-02 |
2021-12-31 |
126376, Co_Coping, NCT04421612 |
Phase Not Applicable |
Recruiting |
1 |
20 Months |
400 |
Tine Nordgreen, PhD |
2020-08-10 |
| The COVID-19 and Healthcare Workers: An Active Intervention |
Anxiety disorder, Coronavirus disease 19 infection, Depression, Phobia, Post traumatic stress disorder |
Video-Based intervention alone, written description alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Research Foundation for Mental Hygiene Inc |
|
US |
2020-08-30 |
2021-01-30 |
8032, NCT04497415 |
Phase Not Applicable |
Not yet recruiting |
1 |
5 Months |
1200 |
Doron Amsalem, MD, Yuval Neria, PhD |
2020-08-14 |
| SignCov: Assesment of the Metabolomic Signature in COVID-19 Patients |
Coronavirus disease 19 infection |
blood and urine sampling alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire De Nice |
|
France |
2020-08-07 |
2021-10-07 |
20-PP-18, NCT04497272, SignCov |
Phase Not Applicable |
Not yet recruiting |
1 |
14 Months |
150 |
OCCELLI Céline, OCELLI Celine |
2020-08-06 |
| Comparison of the Effectiveness of Compassionate Therapy and Positive Psychology with Well-being Approach on Alexithymia, Adaptive Behavior, Adherence of Treatment and Biological Factors in Patients with Diabetes Type 2 |
Coronavirus disease 19 infection, Non-insulin dependent diabetes, Psychiatric disorder |
Compassionate Therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Islamic Azad University |
|
Iran |
2020-05-21 |
|
IR.HUMS.REC.1399.105, IRCT20191023045222N1 |
Phase Not Applicable |
No longer recruiting |
1 |
|
100 |
Dr. Leila Moradi, Mahnaz Bahadori, Mahnaz Mehrabizadeh Honarmand |
2020-08-06 |
| Study of F-652 (IL-22:IgG2 Fusion Protein) in Patients With Moderate to Severe COVID-19 |
Coronavirus disease 19 infection |
F-652 alone |
IL-22 agonist, Interleukin 22 ligand |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Evive Biotech |
|
US |
2020-08-10 |
2021-02-28 |
GC-652-04, NCT04498377 |
Phase 2 Clinical |
Not yet recruiting |
1 |
6 Months |
38 |
Christine M Bojanowski, MD, William L Daley, MD |
2020-08-08 |
| BLAZE-2: A Study of LY-3819253 (LY-CoV555) in Preventing SARS-CoV-2 Infection and COVID-19 in Nursing Home Residents and Staff |
Coronavirus disease 19 infection |
LY-CoV555 alone |
COVID19 Spike glycoprotein modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Eli Lilly & Co |
AbCellera Biologics Inc, National Institute of Allergy and Infectious Diseases |
US |
2020-08-02 |
2021-06-29 |
18063, BLAZE-2, COVPN #3501, J2X-MC-PYAD, NCT04497987 |
Phase 3 Clinical |
Recruiting |
11 |
10 Months |
2400 |
Carl Fichtenbaum, Christine Thai, Christopher Hall, David Wohl, G Taffet, Ian Frank, M C Patel, S Doblecki-Lewis, Srilatha Edupuganti, Stockton Mayer, Sue Ellen Abdalian |
2020-08-14 |
| COVID-19-Positive Outpatient Thrombosis Prevention in Adults Aged 40 to 79 |
Coronavirus disease 19 infection, Inflammatory disease, Thrombosis |
apixaban alone, aspirin alone |
Factor Xa antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
University of Pittsburgh |
National Heart Lung and Blood Institute |
US |
2020-08-31 |
2021-03-31 |
ACTIV4-OUTPATIENT, NCT04498273 |
Phase 3 Clinical |
Not yet recruiting |
1 |
7 Months |
7000 |
Frank Sciurba, Jean Connors, Paul Ridker, M.D. |
2020-08-08 |
| CoCo-20: A Longitudinal Follow-up Study of the French Pediatric Population During and After the Coronavirus Pandemic COVID-19 |
Coronavirus disease 19 infection, Post traumatic stress disorder, Psychiatric disorder |
emergency semi-directed interview alone, mental health assessment alone |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) |
Fondation Lenval |
|
France |
2020-04-27 |
2020-12-31 |
20-HPNCL-05, CoCo-20, NCT04498416 |
Phase Not Applicable |
Recruiting |
1 |
8 Months |
70 |
Arnaud FERNANDEZ, MD, Arnaud Fernandez, Aurélien Richez, Florence Gittard-Askenazy, Pr, Michèle Battista, Morgane GINDT, Morgane Gindt, Ophélie Nachon |
2020-08-09 |
| Evaluating the Effect of NT-I7, a Long Acting Interleukin-7, to Increase Lymphocyte Counts and Enhance Immune Clearance of SARS-CoV-2 (COVID-19) |
Coronavirus disease 19 infection |
NT-17 alone, Standard of care treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Washington University School of Medicine, US |
NeoImmuneTech Inc |
US |
2020-09-30 |
2021-06-30 |
06-29-20-CAMPIAN, NCT04498325 |
Phase 1 Clinical |
Not yet recruiting |
1 |
9 Months |
42 |
Alexandre Lacasse, M.D., Erik R Dubberke, M.D., MSPH, Jian Campian, M.D., Ph.D., Mary McLennan, M.D. |
2020-08-10 |
| Psychological Impact, Mental Health and Sleep Disorder Among Patients Hospitalized and Health Care Workers During the 2019 Coronavirus Outbreak (COVID-19) |
Coronavirus disease 19 infection, Psychiatric disorder, Sleep disorder |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Brugmann University Hospital |
|
Belgium |
2020-05-29 |
2020-12-31 |
CHU-COVIDIMPACT, NCT04497246 |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
5000 |
Maxime Windal, Murielle Surquin, Head of geriatry department, Sophie Levy, Sophie Levy, MD |
2020-08-06 |
| Psychosocial Outcomes in Families of COVID-19 ICU Patients |
Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Liege |
|
Belgium |
2020-04-16 |
2020-09-30 |
FAMILY COVID, NCT04498507 |
Phase Not Applicable |
Recruiting |
1 |
5 Months |
50 |
Anne-Françoise Rousseau, MD, PhD, Anne-Françoise Rousseau, PhD, Rousseau, MD, PhD |
2020-08-06 |
| Mask Usage and Exercise During the COVİD-19 Pandemic |
Coronavirus disease 19 infection, Dyspnea, Fatigue |
Exercise tests alone, Surgical mask alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
KTO Karatay University |
|
Turkey |
2020-07-20 |
2021-09-30 |
KARATAYU3, NCT04498546 |
Phase Not Applicable |
Recruiting |
1 |
14 Months |
60 |
Büşra Alkan, MsC, PT, RA, Büşra Alkan, MsC, Pt, RA, Büşra Alkan, Research Assistant, Sevgi Özalevli, Prof, PT, Özlem Akkoyun Sert, Phd, PT |
2020-08-07 |
| TOMOCOVIDMX: Tomographic Findings in COVID-19 and Influenza |
Coronavirus disease 19 infection, Influenza virus A infection, Viral pneumonia |
pulmonary tomography alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universidad De Guanajuato |
Hospital General Regional de León, University Medical Center Groningen |
Mexico |
2020-06-15 |
2022-04-30 |
HGL-ENSE-00743-20, NCT04497311, TOMOCOVIDMX |
Phase Not Applicable |
Recruiting |
1 |
22 Months |
100 |
Jaime Daniel Mondragón Uribe, Medical researcher, Lourdes N Veléz-Ramírez, M.D., Lourdes N Vélez-Ramírez, M.D., Omar Jiménez-Zarazúa, M.D. |
2020-08-07 |
| Sofosbuvir Containing Regimens in Treatment of COVID 19 Patients |
Coronavirus disease 19 infection |
sofosbuvir + ledipasvir (fixed-combination/oral, HCV/HBV), Gilead alone, standard of care treatment alone, Variable regimens including daclatasvir , ribavirin , sofosbuvir |
Hepatitis C virus NS5B polymerase inhibitor, Hepatitis C virus protein NS5A inhibitor |
|
Tanta University |
|
Egypt |
2020-07-01 |
2030-12-10 |
NCT04497649, TANTA SOFOSBUVIR COVID |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
125 Months |
200 |
Marwa Salama, Lecturer, Sherief Abd-Elsalam, ass. prof., sherief Abd-Elsalam, ass. Prof., sherief abd-elsalam, ass. prof, sherief abd-elsalan, ass. prof. |
2020-08-08 |
| A Study to Assess Safety, Tolerability, and Immunogenicity of V-591 (COVID-19 Vaccine) in Healthy Participants |
Coronavirus disease 19 infection |
MERS-Corona virus vaccine (recombinant live-attenuated measles virus vector), Themis alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Merck Sharp & Dohme Corp |
|
|
2020-08-19 |
2022-03-16 |
2020-003493-46, NCT04498247, V591-001 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
0 |
18 Months |
260 |
Medical Director |
2020-08-07 |
| Changes in Out-patient Visits in Taiwan During the Time of Global COVID-19 Pandemic |
Coronavirus disease 19 infection |
|
|
|
National Taiwan University Hospital |
|
Taiwan |
2020-08-01 |
2020-12-31 |
202006225RINA, NCT04497467 |
Phase Not Applicable |
Recruiting |
1 |
5 Months |
1200000 |
Wan-Ching Lien, Wan-Ching Lien, PhD |
2020-08-06 |
| Clinical trial for the treatment of COVID-19 with Chloroquine and Colchicine |
Coronavirus disease 19 infection |
chloroquine plus colchicine |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital das Clinicas de Ribeirao Preto/USP |
Conselho Nacional de Desenvolvimento Cientifico e Tecnologico - CNPq, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Fundacao de Amparo a Pesquisa do Estado Sao Paulo |
|
2020-04-11 |
2020-09-30 |
3.954.378, 30248420.9.0000.5440, 30248420.9.0000.5440, 30248420.9.3001.5403, 4.066.630, 4.112.255, RBR-8jyhxh, U1111-1255-6304 |
Phase 2/Phase 3 Clinical |
Recruiting |
0 |
5 Months |
60 |
Renê D. Ribeiro Oliveira |
2020-08-06 |
| Educational intervention by cell phone to increase informed choices at childbirth, in the context of the Covid-19 pandemic |
Coronavirus disease 19 infection, Pregnancy disorder |
PiniOn alone, educational communication intervention alone |
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Sociedade Beneficente Israelita Brasileira Hospital Albert Einsten, University of Sao Paulo |
|
Brazil |
2020-08-28 |
|
32840920.7.0000.0071, 4.132.178, RBR-3g5f9f, U1111-1255-8683 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
20000 |
Carmen Simone Grilo Diniz, Edson Amaro Junior, Livia Sanches Pedrilio |
2020-08-06 |
| STRING-COVID: Mental Health Impact of the COVID-19 Pandemic Among Migrants in Chile |
Coronavirus disease 19 infection, Psychiatric disorder |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Pontificia Universidad Catolica De Chile |
Chilean Science Council |
Chile |
2020-07-03 |
2021-01-31 |
170519004, NCT04497636, STRING-COVID |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
1092 |
Antonia Errazuriz, PhD |
2020-08-08 |
| Safety and Feasibility of Amniotic Fluid as a Treatment for COVID-19 Patients |
Coronavirus disease 19 infection, Inflammatory disease |
acellular sterile filtered human amniotic fluid alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Utah |
|
US |
2020-08-15 |
2021-08-15 |
132922, NCT04497389 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
12 Months |
60 |
Alyssa Messina, MA, Craig Selzman, MD |
2020-08-07 |
| Acalabrutinib Study With Best Supportive Care in Participants Hospitalized With COVID-19 |
Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia |
Nasogastric tube alone, Proton pump inhibitor therapy alone, acalabrutinib alone |
Btk tyrosine kinase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
AstraZeneca plc |
Acerta Pharma BV |
US |
2020-07-31 |
2020-09-28 |
D822FC00005, NCT04497948 |
Phase 1 Clinical |
Not yet recruiting |
3 |
1 Month |
20 |
AstraZeneca Clinical Study Information Center |
2020-08-07 |
| Evaluation of the effectiveness of Cyclotide complex herbal syrup in preventing COVID-19 virus in exposed individuals |
Coronavirus disease 19 infection |
Variable regimens including Pimpinela anisum hydroalcoholic extract , Ziziphus spina-cristi , cyclopeptide fraction , orange peel |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Bagheiat-allah University of Medical Sciences |
|
Iran |
2020-04-20 |
|
IR.BMSU.REC.1399.250, IRCT20160131026298N4 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
|
60 |
AHMAD REZA SHARIFI OLOUNABADI, Gholamhosein Alishiri, Shiva Shamshiri, shiva shamshiri |
2020-08-08 |
| Effect of Corton on olfactory dysfunction in COVID-19 patients |
Coronavirus disease 19 infection, Dysomia |
mometasone alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Mashhad University of Medical Sciences |
|
Iran |
2020-07-18 |
|
IR.MUMS.REC.1399.355, IRCT20200522047542N1 |
Phase 1 Clinical |
Recruiting |
1 |
|
70 |
Masoumeh Hosseinpour |
2020-08-07 |
| COMS-19: COVID-19 and SARS-CoV-2 Antibodies in Multiple Sclerosis Patients |
Coronavirus disease 19 infection, Multiple sclerosis |
Sars-CoV-2 RBD total antibody test (Sanquin) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
VU University Medical Center |
|
Netherlands |
2020-08-06 |
2021-12-01 |
COMS-19, NCT04498286, NL74243.029.20 |
Phase Not Applicable |
Recruiting |
1 |
15 Months |
800 |
Joep Killestein, Zoé L van Kempen |
2020-08-08 |
| COVID-HEART study: COVID-19 effects on the heart |
Coronavirus disease 19 infection, Heart disease |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Leeds |
National Institute for Health Research (NIHR), United Kingdom Research & Innovation |
UK |
2020-04-16 |
2022-07-31 |
CD20/133244, COVID-HEART study, ISRCTN58667920 |
Phase Not Applicable |
Recruiting |
18 |
27 Months |
370 |
Dr Laura Jones (public),, Kathryn Somers (public), Prof Greenwood |
2020-08-10 |
| SabanaHerons: Clinical Evaluation of Ventilador Innovation Product in Colombia in the SARS COVID 19 Pandemic, Unisabana Herons |
Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure, Traumatic brain injury |
Unisabana-Herons ventilator alone, Volume-controlled mechanical ventilation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Fundación Neumologica Colombiana |
Clínica Universidad de La Sabana, Fundación Cardioinfantil-Instituto De Cardiología, Universidad de la Sabana |
Colombia |
2020-07-28 |
2020-12-31 |
202006-25502, NCT04497623, SabanaHerons |
Phase 1 Clinical |
Not yet recruiting |
3 |
5 Months |
5 |
Alirio R Bastidas, MD, MSc, Fabio A Varon-Vega, MD, PhD(c), Luis F Giraldo-Cadavid, MD, PhD |
2020-08-07 |
| DOMY COVID: Myocardial Damages Related to COVID-19 |
Coronavirus disease 19 infection, Heart injury, Myocarditis |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire Dijon |
|
France |
2020-03-01 |
2021-07-31 |
COTTIN AOIC 2020, DOMY COVID, NCT04498065 |
Phase Not Applicable |
No longer recruiting |
1 |
17 Months |
200 |
|
2020-08-07 |
| An Epidemiological Investigation on Correct Wearing of Mask by Direct Spray Test |
Coronavirus disease 19 infection, Respiratory disease |
FT-30 qualitative fitness test system (3M) alone, mask wearing alone, spray test alone |
|
Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cardiovascular Institute and Fuwai Hospital |
|
China |
2020-06-19 |
2020-08-31 |
2020-KZLXB-02-01, NCT04497675 |
Phase Not Applicable |
Recruiting |
8 |
2 Months |
10000 |
Bin Wen, Duo lin, Lin C Duo, Lin Duo, Lin H Duo, Pengxu H Kong, Rundi Deng, Xiang-Bin Pan |
2020-08-13 |
| EPI CV COVID: Epidemiological Approaches to the Cardiovascular Consequences of COVID-19 |
Coronavirus disease 19 infection, Myocardial infarction, Respiratory failure, Sepsis, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire Dijon |
|
France |
2020-03-15 |
2021-07-31 |
EPI CV COVID, NCT04498091, ZELLER AOIC 2020 |
Phase Not Applicable |
No longer recruiting |
1 |
16 Months |
35 |
|
2020-08-08 |
| G-COV: Sex-Informed Data in the COVID-19 Pandemic |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universita degli Studi di Roma La Sapienza |
|
Italy |
2020-09-01 |
2022-06-01 |
G-COV, NCT04497402, SAPIENZAGENDERCOVID |
Phase Not Applicable |
Not yet recruiting |
1 |
21 Months |
88 |
Claudio Mastroianni, MD, Guido Antonelli, MD, Lucia Stefanini, PhD, Marcella Visentini, MD, Maria Ciardi, MD, Roberto Cangemi, MD, Stefania Basili, Stefania Basili, MD, Stefano Corradini, MD, Valeria Raparelli, MD |
2020-08-14 |
| An Epidemiological Investigation on Correct Wearing of Mask by Hood Test |
Coronavirus disease 19 infection, Respiratory disease |
FT-30 qualitative fitness test system (3M company) alone, breathing test alone, fitness test spray reagent alone, hood wearing test alone, sensitivity test alone, suitability testing alone |
|
Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cardiovascular Institute and Fuwai Hospital |
|
China |
2020-06-19 |
2020-08-31 |
2020-KZLXB-02-02, NCT04497753 |
Phase Not Applicable |
Recruiting |
8 |
2 Months |
10000 |
Bin Wen, Duo H lin, Lin Duo, Pengxu Kong, Rundi Deng, Xiang-Bin Pan |
2020-08-12 |
| A randomized, double-blind trial to determine whether convalescent blood plasma therapy can effectively be used for the prevention of people who have been exposed to COVID-19 in their home or at work as health care providers |
Coronavirus disease 19 infection |
convalescent blood plasma therapy alone |
|
|
Johns Hopkins Technology Ventures |
US Department of Defense |
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
500 |
|
2020-08-05 |
| ECHO-vid: Stress Echocardiography in Patients Recovery From Mild COVID-19 Illness |
Coronavirus disease 19 infection |
echocardiography alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Hospital Beneficencia Espanola de Puebla |
|
Mexico |
2020-09-01 |
2020-11-30 |
CARDIOLOGY-004, ECHO-vid, NCT04498299 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
30 |
Consuelo Orihuela Sandoval, Jaime Hernandez-Montfort, Miguel Ayala León, Cardiolology, Miguel Ayala-Leon, Rosa Tzompantzi-Flores, Victoria Delgado, miguel ayala-leon |
2020-08-07 |
| A randomized, double-blind trial to determine whether convalescent blood plasma therapy can effectively be used to treat people in the early stage of COVID-19 illness |
Coronavirus disease 19 infection |
convalescent blood plasma therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Johns Hopkins Technology Ventures |
US Department of Defense |
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
600 |
|
2020-08-05 |
| Registry of COVID-19 Patients at AOUI Verona |
Coronavirus disease 19 infection |
|
|
|
Azienda Ospedaliera Universitaria Integrata Di Verona |
|
Italy |
2020-03-01 |
2020-09-30 |
COVID19-VR, NCT04497194 |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
500 |
Evelina Tacconelli, Evelina Tacconelli, Professor |
2020-08-10 |
| SARS-CoV-2 (COVID-19) Detection Using the Breath Analyzer TeraSystem |
Coronavirus disease 19 infection |
breath detector analyzer (TeraSystem) alone, rapid detection breath test alone |
|
Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Instituto Costarricense de Investigaciones Clínicas ICIC |
|
Costa Rica |
2020-08-04 |
2020-08-15 |
NCT04497610, TERA-CR-1 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1000 |
Dr. Guillermo Rodríguez Gómez, Guillermo Rodríguez Gomez, MD |
2020-08-07 |
| Virtual White Boards for Patient Satisfaction |
Coronavirus disease 19 infection |
virtual display screen (e-ink screen) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Brigham & Women's Hospital |
E Ink Corp |
US |
2020-08-20 |
2021-04-17 |
2020P002382, NCT04497922 |
Phase Not Applicable |
Not yet recruiting |
1 |
7 Months |
100 |
Guruprasad D Jambaulikar, MBBS MPH, Peter R Chai, MD, Peter R Chai, MD MMS |
2020-08-07 |
| Analysis of Coronavirus Disease 19 (COVID-19) Convalescent Plasma |
Coronavirus disease 19 infection |
convalescent plasma alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
City of Hope Medical Center |
National Cancer Institute |
US |
2020-08-21 |
2022-08-21 |
20204, NCI-2020-04000, NCT04497779, P30CA033572 |
Phase Not Applicable |
Not yet recruiting |
1 |
24 Months |
800 |
John Zaia |
2020-08-08 |
| Netizens' Perception of COVID-19 Information and Information Sources |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Qassim University |
|
Saudi Arabia |
2020-06-10 |
2020-08-15 |
NCT04497441, QASSIMU3 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
385 |
Bugude Shiva Shankar, MDS, Shiva Shankar Bugude, MDS |
2020-08-07 |
| Correlation Fear of COVID-19 and Dental Treatment Anxiety |
Anxiety disorder, Coronavirus disease 19 infection, Tooth disease |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Qassim University |
|
Saudi Arabia |
2020-06-16 |
2020-07-25 |
NCT04497818, QASSIMU2 |
Phase Not Applicable |
Completed |
1 |
1 Month |
385 |
Bugude Shiva Shankar |
2020-08-07 |
| An observational study of the treatment of patients with mild and moderate COVID-19 (including suspected patients) |
Coronavirus disease 19 infection |
Kampo medicine alone, Western medicine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tohoku University Hospital |
|
Japan |
2020-07-04 |
|
UMIN000041301 |
Phase Not Applicable |
Recruiting |
1 |
|
1000 |
Akiko Kuwabara, Shin Takayama |
2020-08-07 |
| Local Tolerability and Pharmacokinetic Evaluation of Cyclops Dry Powder Hydroxychloroquine Inhalation in Healthy Volunteers |
Coronavirus disease 19 infection |
hydroxychloroquine alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
University Medical Center Groningen |
|
Netherlands |
2020-09-15 |
2020-11-15 |
CARRIED-01, NCT04497519 |
Phase 1 Clinical |
Recruiting |
1 |
2 Months |
12 |
Onno Akkerman, Onno Akkerman, MD |
2020-08-07 |
| RESTART-19: Risk prediction of indoor Sports And culture events for the Transmission of COVID-19 |
Coronavirus disease 19 infection |
conventional processes alone, culture events alone, hygiene-optimized processes alone, indoor Sports alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Wittenberg University |
Ministerium für Wirtschaft, Wissenschaft und Digitalisierung des Landes Sachsen-Anhalt, Sächsisches Staatsministerium für Soziales und Gesellschaftlichen Zusammenhalt |
Germany |
2020-08-22 |
|
2020-095, DRKS00022790, RESTART-19 |
Phase Not Applicable |
Recruiting |
1 |
|
4000 |
Angelika Ihling, Stefan Moritz |
2020-08-12 |
| COVID-19-101: Clinical Trial to Evaluate the Safety and Immunogenicitiy of the COVID-19 Vaccine |
Coronavirus disease 19 infection |
COVID-19 vaccine (measles vaccine vector technology), Institut Pasteur/Themis Bioscience/University of Pittsburgh alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Institut Pasteur, Themis Bioscience GmbH, University of Pittsburgh |
ABL Europe, Coalition for Epidemic Preparedness Innovations |
France, Belgium |
2020-08-10 |
2021-10-31 |
2020-002973-89, 2020-016, COVID-19-101, NCT04497298 |
Phase 1 Clinical |
Recruiting |
2 |
14 Months |
90 |
Christiane GERKE, PhD, Cécile ARTAUD, Mohand AIT AHMED, Odile LAUNAY, MD, PhD, Robin ROGIERS, MD |
2020-08-13 |
| A study to assess OraSure’s OMNIgene oral device for SARS-CoV-2 Saliva Test |
Coronavirus disease 19 infection |
OMNIgene alone |
|
|
OraSure Technologies Inc |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
|
|
2020-08-06 |
| Evaluate the efficacy of hydroxychloroquine in the prevention of SARS-COV2 infection in high risk health care workers |
Coronavirus disease 19 infection |
hydroxychloroquine alone |
|
|
Isfahan University of medical Sciences |
|
Iran |
2020-04-18 |
|
IR.MUI.MED.REC.1399.0.17, IRCT20200414047076N1 |
Phase 2 Clinical |
Recruiting |
2 |
|
160 |
Elahe Nasri, elahe Nasri |
2020-08-07 |
| CCPSEI: Clinical Characterization Protocol for Severe Infectious Diseases |
Coronavirus disease 19 infection, Respiratory tract infection |
sampling alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Johns Hopkins University |
|
US |
2020-04-09 |
2021-06-30 |
CCPSEI, IRB00245545, NCT04496466 |
Phase Not Applicable |
Recruiting |
1 |
14 Months |
500 |
Lauren Sauer, MS |
2020-08-07 |
| CO-FRAIL: Frailty and adverse outcomes in adults hospitalized for COVID-19 |
Cognitive disorder, Coronavirus disease 19 infection, Respiratory distress syndrome |
|
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo |
|
Brazil |
2020-03-30 |
|
32037120.6.0000.0068, 4.050.650, CO-FRAIL, RBR-7w5zhr, U1111-1252-9993 |
Phase Not Applicable |
Recruiting |
1 |
|
2000 |
Márlon Juliano Romero Aliberti, Thiago Junqueira Avelino-Silva |
2020-08-06 |
| Physical and Psychological Impact of the COVID-19 Pandemic in Germany- a Survey of General Practitioners |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sauerlandpraxis Medebach, Hallenberg, Winterberg |
|
Germany |
2020-08-10 |
|
2020-449-f-S, DRKS00022157 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
500 |
Simon Wernhart |
2020-08-06 |
| PraeCoSa: Precalence study on ICU Treatment of COVID-19 patients in Northern and Western Saxony in the first half of 2020 - PraeCoSa |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
UniversitätsKlinikum Leipzig |
Deutsche Forschungsgemeinschaft (DFG) |
Germany |
2020-08-01 |
|
196/20-ek, DRKS00021705, PraeCoSa |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Christian Seeber |
2020-08-06 |
| PsyCovART: Psychological Impact of COVID-19 Among Women Undergoing Infertility Treatment |
Coronavirus disease 19 infection, Psychiatric disorder |
|
|
Female, Young Adults (18-44 yrs) |
Hospices Civils De Lyon |
|
France |
2020-07-31 |
2020-12-31 |
69HCL20_0577, NCT04496869, PsyCovART |
Phase Not Applicable |
Not yet recruiting |
1 |
5 Months |
600 |
Eloise FRAISON, MD, Océane LABLANCHE, Resident |
2020-08-06 |
| COVID-19 Anosmia Study |
Coronavirus disease 19 infection, Dysomia |
omega-3 fatty acid alone |
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Mount Sinai Medical Center |
|
US |
2020-07-15 |
2021-06-30 |
GCO 20-1132, NCT04495816 |
Phase 2 Clinical |
Recruiting |
1 |
11 Months |
126 |
Alfred-Marc Iloreta, MD, David K Lerner, MD |
2020-08-06 |
| A study of therapeutic effect of blood ozone therapy of severe Covid-19 patients |
Coronavirus disease 19 infection |
Variable regimens including IFN beta-1a , IFN beta-1b , atazanavir + ritanavir , chlroquine phosphate , dexamethasone , enoxaparin sodium , heparin , hydroxychloroquine , lopinavir + ritonavir , ozone |
HIV protease inhibitor, Low molecular weight heparin |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Ahvaz University of Medical Sciences |
|
Iran |
2020-08-05 |
|
IR.AJUMS.REC.1399.217, IRCT20200616047792N1 |
Phase 2 Clinical |
Recruiting |
1 |
|
60 |
Behnam Sheibani, Dr. Behnam Sheibani, Dr. Mohammad Badavi, Shokrollah Salmanzadeh Ramhormozi |
2020-08-06 |
| A study of the COVID-19 sequlae |
Coronavirus disease 19 infection |
chest CT alone, pulmonary function test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Japanese Respiratory Society |
Japanese Ministry of Health, Labor and Welfare |
Japan |
2020-08-01 |
|
UMIN000041168 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1000 |
Akihito Yokoyama, Kazufumi Takamatsu |
2020-08-06 |
| COVID-19 Neurological Manifestation |
Coronavirus disease 19 infection, Neurological disease |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Pittsburgh |
|
US |
2020-04-13 |
2020-12-31 |
NCT04496128, STUDY20040037 |
Phase Not Applicable |
Recruiting |
1 |
8 Months |
300 |
Sherry H Chou, MD, MSc |
2020-08-10 |
| COVID-19 Brain Injury |
Brain hemorrhage, Cerebral hemorrhage, Coronavirus disease 19 infection, Ischemic stroke, Status epilepticus, Traumatic brain injury |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Pittsburgh |
|
US |
2020-04-02 |
2020-12-31 |
NCT04496076, STUDY20030201 |
Phase Not Applicable |
Recruiting |
1 |
8 Months |
300 |
Sherry H Chou, MD, MSc |
2020-08-10 |
| COPE: Covid-19 progression in end-stage kidney disease |
Coronavirus disease 19 infection, End stage renal disease |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
DaVita Clinical Research |
|
|
2020-08-01 |
2021-03-31 |
20-M-0047-00, COPE, NCT04495907 |
Phase Not Applicable |
Not yet recruiting |
0 |
8 Months |
1000 |
|
2020-08-06 |
| Evaluation of Commercial SARS-CoV-2 Antibody Immunoassays for COVID-19 |
Coronavirus disease 19 infection |
commercial SARS-CoV-2 antibody immunoassay alone |
|
Healthy volunteers accepted |
Hong Kong Sanatorium & Hospital |
|
Hong Kong |
2020-07-27 |
2020-11-30 |
NCT04496141, RC-2020-12 |
Phase Not Applicable |
No longer recruiting |
1 |
4 Months |
70 |
Jonpaul Sze Tsing Zee, MBChB |
2020-08-06 |
| RePAiR: Registry of Sustained Immunity to COVID-19 Among ESKD Patients |
Coronavirus disease 19 infection, End stage renal disease |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
DaVita Clinical Research |
|
US |
2020-07-20 |
2021-03-31 |
20-M-0044-00, NCT04495764, RePAiR |
Phase Not Applicable |
Recruiting |
13 |
8 Months |
2500 |
Aleah Freeman, Ali Stockness, Christina Fernandez, David Ellis, Dylan Marias, Francesca Tentori, MD, Helen Brickel, Helen Brickel, RN, Hoda Bashir, Jason Harvey, Marisol Ortega, Nicole Holquin, Tracy Mente |
2020-08-13 |
| A comparative study of the effects of Tocilizumab, interferon-gamma and vitamin C on the recovery of critically ill COVID-19 patients and cytokine storm |
Coronavirus disease 19 infection, Inflammatory disease |
routine medication alone, tocilizumab alone, Vitamin C plus interferon gamma |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Tabriz University of Medical Sciences |
|
Iran |
2020-07-31 |
|
IR.TBZMED.REC.1399.130, IRCT20200525047570N1 |
Phase 2 Clinical |
No longer recruiting |
1 |
|
60 |
Mohammad Hossein Somi, Negin Hadisi |
2020-08-12 |
| Ethics of Behavioral Interventions during the Covid 19 |
Coronavirus disease 19 infection |
Ethics of Public Health Behavioral Interventions alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Forum for Ethical Review Committees in the Asian and Western Pacific Region (FERCAP) |
Seth GS Medical College |
India |
2020-07-31 |
|
CTRI/2020/07/026926 |
Phase Not Applicable |
Not yet recruiting |
5 |
|
400 |
Dr Yashashri C Shetty |
2020-08-06 |
| Desferal in COVID-19 |
Coronavirus disease 19 infection |
Desferal (Exirdaru Company) plus hydroxychloroquine sulfate (Amin Pharmaceutical company) |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Bandare-abbas University of Medical Sciences |
|
Iran |
2020-08-10 |
|
IR.HUMS.REC.1399.227, IRCT20200506047323N4 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
|
60 |
Mohammad Fathalipour, Parivash Davoodian, Teamur Aghamolaei |
2020-08-12 |
| To see the effect of twakadi (tea made up of dalcheeni, tulasi pepper, clove, etc) tea on police worker who have a duty in covid 19 pandemic |
Coronavirus disease 19 infection |
Twakadi herbal tea (tulasi, Pippali, yashtimadhu, Ginger, Draksha, Dalchini) alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
PDEAs C.A.R.C |
|
India |
2020-07-31 |
|
CTRI/2020/07/026925 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
60 |
Dr Yogini Kulkarni |
2020-08-06 |
| A phase I clinical trial of JNJ-78436735 for the prevention of Coronavirus disease 19 infection |
Coronavirus disease 19 infection |
JNJ-78436735 alone |
|
|
Johnson & Johnson |
|
Japan |
|
|
|
Phase 1 Clinical |
Planned |
1 |
|
|
|
2020-08-04 |
| A phase IIa clinical trial of JNJ-78436735 for the prevention of Coronavirus disease 19 infection |
Coronavirus disease 19 infection |
JNJ-78436735 alone |
|
|
Johnson & Johnson |
|
Spain, Netherlands, Germany |
|
|
|
Phase 2a Clinical |
Planned |
3 |
|
|
|
2020-08-04 |
| Evaluation study of preventing exacerbations for home care patients with chronic diseases by using dual-monitoring-based telenursing system - a prospective, longitudinal, mixed methods study |
Angina, Cardiac failure, Chronic obstructive pulmonary disease, Coronary artery disease, Coronavirus disease 19 infection, Diabetes mellitus, Diabetic nephropathy, Heart valve disease, Idiopathic pulmonary fibrosis, Lung tumor, Motor neurone disease, Myocardial disease, Pneumonia |
dual-monitoring telenursing alone |
|
Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hamamatsu University School of Medicine, St. Luke's International University, Japan, Tokyo Healthcare University, Tokyoto Igaku Kenkyu Kiko |
Ministry of Education, Culture, Sports, Science and Technology of Japan |
Japan |
2020-08-27 |
|
UMIN000041160 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
42 |
Tomoko Kamei |
2020-08-11 |
| Ayurvedic intervention in COVID-19 patients |
Coronavirus disease 19 infection |
Variable regimens including Ashwagandha (Withania somniferum) , Rasona Kalka , Samshamani Vati , Vyaghryadi kwatha |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Lok Bandhu Sri Raj Narayan Combined Hospital |
|
India |
2020-08-04 |
|
CTRI/2020/07/026922 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
30 |
Adil Rais |
2020-08-14 |
| BARCONA: BARCONA: A Study of Effects of Bardoxolone Methyl in Participants With SARS-Corona Virus-2 (COVID-19) |
Coronavirus disease 19 infection |
bardoxolone methyl (oral, pulmonary arterial hypertension/ diabetic nephropathy), Reata/ Kyowa Hakko Kirin alone |
I-kappa B kinase inhibitor, Kelch like ECH associated protein 1 modulator, NFE2L2 gene stimulator, Nuclear factor kappa B inhibitor, STAT3 gene inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
NYU Langone Health, Reata Pharmaceuticals Inc |
|
US |
2020-08-01 |
2021-02-28 |
20-00591, BARCONA, NCT04494646 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
7 Months |
440 |
Alexander Slotwiner, MD, Atul Sharma, MD, Carlos Alviar, MD, Eugene Yuriditsky, MD, James Horowitz, MD, Juan Gaztanaga, MD, Kevin Chan, Kevin Marzo, MD, Norma Keller, MD, Sripal Bangalore, MD, MHA |
2020-08-05 |
| An integrated clinico-molecular-epidemiological approach to advance knowledge of COVID-19 |
Coronavirus disease 19 infection |
|
|
|
Monash University, Universiti Sains Malaysia |
|
Malaysia |
|
|
NMRR-20-1645-55277 |
Phase Not Applicable |
Not yet recruiting |
5 |
|
|
Assoc. Prof Rosline Hassan, Associate Professor Qasim Ayub, DR Chan Yean Yean, DR HAJAH FAIZAN BINTI HAJI GHAZALI, Dr Murnihayati binti Hassan, Dr. Mohammad Ridhuan Bin Mohd Ali, Engku Nur Syafirah bt Engku Abd Rahman, Mr. Chua Wei Lian Chua Wei Lian, noor hafizan binti mat salleh |
2020-08-06 |
| KAP towards COVID-19 in RMCO, Sarawak |
Coronavirus disease 19 infection |
|
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sarawak General Hospital |
|
Malaysia |
2020-08-01 |
2020-08-31 |
NMRR-20-1643-55867 |
Phase Not Applicable |
Not yet recruiting |
1 |
1 Month |
|
Dr. Benjamin Sachdev A/L Manjit Singh |
2020-08-06 |
| A Clinical trial to evaluate the effect of a combination of treatment of Reginmune capsule and Immunofree tablets in the treatment of mild to moderate COVID-19 patients |
Coronavirus disease 19 infection |
Immunofree alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Corival Lifesciences Private Limited |
|
India |
2020-08-07 |
|
CTRI/2020/08/026957 |
Phase 4 Clinical |
Not yet recruiting |
4 |
|
100 |
Dr Abhijit Munshi, Dr Vijaykumar Kamat |
2020-08-05 |
| Telemedicine effectiveness during COVID-19 |
Coronavirus disease 19 infection |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Prasanna School of Public Health |
|
India |
2020-08-10 |
|
CTRI/2020/08/026956 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
|
Brayal DSouza |
2020-08-03 |
| COVID-19 Drug Utilization |
Coronavirus disease 19 infection, Influenza virus infection, Respiratory tract infection |
COVID-19 treatment alone |
|
|
Ministry of Health, Malaysia |
|
Malaysia |
2020-08-01 |
|
55865, NMRR-20-1648-55865 |
Phase Not Applicable |
Status not specified |
1 |
|
|
Dr Abdul Haniff bin Mohamad Yahaya, Dr Nor Ilham Ainaa Binti Muhsin |
2020-08-06 |
| COVID-19 Preparedness and Response in Malaysia |
Coronavirus disease 19 infection |
|
|
|
Hospital Sungai Buloh |
|
Malaysia |
2020-07-31 |
2020-08-07 |
55974, NMRR-20-1646-55974 |
Phase Not Applicable |
Status not specified |
1 |
|
|
Dr Kalaiarasu Peariasamy, Dr Kuan Pei Xuan |
2020-08-06 |
| Comparison of three homoeopathic drugs for covid-19 immune boosters against standard treatment |
Coronavirus disease 19 infection |
Arsenicum album 30c alone, Camphora officinalis alone, Sarcolactic acid 30 alone, Variable regimens including Zinc |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Ministry of Ayush, National Institute of Homoeopathy |
|
India |
2020-08-03 |
|
CTRI/2020/07/026953 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
704 |
Dr. Prasanta rath |
2020-08-05 |
| Survey and Management of depression, Anxiety and Stress due to COVID-19 fear |
Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression |
Brahmi (Bacopa monnieri (L.) Pennell) capsule alone |
|
Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
SDM College of Ayurveda and Hospital |
|
India |
2020-08-01 |
|
CTRI/2020/07/026952, DAS-COVID-19-AYU |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
200 |
Dr Prasanna N Rao, Dr Shailaja U |
2020-08-05 |
| Effects of revised COVID-19 specific infection control protocol on the well being of dental professionals |
Coronavirus disease 19 infection |
personal protective equipment (PPE) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Manipal College of Dental Sciences |
|
India |
2020-08-03 |
|
CTRI/2020/07/026943 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
300 |
Dr Shruthi Acharya |
2020-08-05 |
| A clinical trail of SARS-CoV-2 vaccine (protein subunit, outer membrane vesicle (OMV)-based peptide), Intravacc/ Epivax for the prevention of Covid-19 |
Coronavirus disease 19 infection |
SARS-CoV-2 vaccine (protein subunit, outer membrane vesicle (OMV)-based peptide), Intravacc/ Epivax alone |
COVID19 Spike glycoprotein modulator |
|
Intravacc |
Celonic AG |
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-08-03 |
| Study of COVID-19 suspected pregnant women |
Coronavirus disease 19 infection |
|
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Kasturba Medical College, Manipal |
|
India |
2020-08-03 |
|
CTRI/2020/07/026942 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
200 |
Nivedita Hegde |
2020-08-05 |
| SARS-COV-2 Infection in Kidney Transplant Recipients: a Brazilian, Multicenter Study |
Coronavirus disease 19 infection, Kidney transplantation |
|
|
|
Hospital do Rim e Hipertensao |
|
Brazil |
2020-05-21 |
2022-04-02 |
30631820.0.1001.8098, NCT04494776 |
Phase Not Applicable |
Recruiting |
1 |
22 Months |
500 |
Helio Tedesco, Jose Osmar Medina, Monica Nakamura |
2020-08-05 |
| What are risk factors associated with disease severity and length of hospital stay in patients admitted with COVID-19 in GCS Medical College, Hospital And Research Center, Ahmedabad? |
Coronavirus disease 19 infection |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Gujarat Cancer Society Medical college hospital and research centre |
|
India |
2020-08-15 |
|
CTRI/2020/07/026955 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
910 |
Arpit C Prajapati |
2020-08-04 |
| Study of blood tests findings in patients of COVID 19 in a tertiary care center |
Coronavirus disease 19 infection |
|
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Gujarat Cancer Society Medical college hospital and research centre |
|
India |
2020-08-10 |
|
CTRI/2020/07/026954 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
150 |
Dr Himali Thakkar |
2020-08-04 |
| Clazakizumab versus Placebo - COVID-19 Infection |
Coronavirus disease 19 infection, Lung disease, Lung injury, Respiratory distress syndrome, Viral pneumonia |
clazakizumab alone |
IL-6 receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Houston Methodist |
|
US |
2020-07-13 |
2021-07-31 |
NCT04494724, PRO00025969 |
Phase 2 Clinical |
Recruiting |
1 |
12 Months |
60 |
Ahmad Goodarzi, MD, Ahmed O Gaber, MD, Alex Rogers, PharmD, Darrel Cleere, BSN, Faisal Zahiruddin, MD, Howard Huang, MD, Howard J Huang, MD, Isioma Agboli, MD, Linda W Moore, PhD, Simon Yau, MD, Yihad G Youssef, MD |
2020-08-10 |
| A clinical study to evaluate the translational insights to better understand the immune response in COVID-19 patients ie, association of COVID-19 inflammation with activation of the C5a-C5aR1 |
Coronavirus disease 19 infection |
|
|
|
Innate Pharma SA |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
|
|
2020-08-05 |
| Observational study of SARS-CoV-2 antibody test positive rate |
Coronavirus disease 19 infection |
SARS-CoV-2 antibody test alone |
|
|
SOUSEIKAI |
|
Japan |
2020-08-01 |
|
UMIN000041262 |
Phase Not Applicable |
Recruiting |
1 |
|
4000 |
Shin Irie, Tatsuya Yoshihara |
2020-08-05 |
| ULSC: Umbilical Cord Lining Stem Cells (ULSC) in Patients With COVID-19 ARDS |
Coronavirus disease 19 infection, Respiratory distress syndrome |
umbilical cord lining stem cells alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Restem LLC |
|
US |
2020-07-23 |
2021-11-30 |
NCT04494386, ULSC, ULSC-CV-01 |
Phase 1/Phase 2 Clinical |
Recruiting |
1 |
16 Months |
60 |
Central Contact, Jason Knudtson, MD, William C Spanos, MD |
2020-08-14 |
| A Study to Investigate the Pharmacokinetics, Efficacy and Safety of INM-005 in Patients With COVID-19 |
Coronavirus disease 19 infection |
INM-005 alone |
Immunoglobulin agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Inmunova |
|
Argentina |
2020-07-27 |
2020-11-30 |
CT-INM005-01, NCT04494984 |
Phase 2/Phase 3 Clinical |
Recruiting |
6 |
4 Months |
242 |
Augusto Perez, MD, Beatriz Firmenich, Estela Izquierdo, MD, Fernando Grittini, MD, Gustavo Chaparro, MD, Ines Zapiola, Mariana Colonna, MSc., Santiago Sanguineti, Ph.D. |
2020-08-10 |
| COVID-19 Core Warming |
Coronavirus disease 19 infection, Respiratory failure |
EnsoETM alone, core warming alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Advanced Cooling Therapy Inc, Attune Medical |
Sharp HealthCare |
US |
2020-08-31 |
2020-12-31 |
COVID CORE WARMING, COVID-19 Core Warming, NCT04494867 |
Phase Not Applicable |
Recruiting |
1 |
4 Months |
20 |
Ahmed Salem, MD, David Willms, MD, Katie Miller |
2020-08-06 |
| Multicenter, registry study of Japanese patients with inflammatory bowel disease with COVID-19 |
Behcets disease, Coronavirus disease 19 infection, Crohns disease, Inflammatory bowel disease, Ulcer, Ulcerative colitis |
|
|
Japanese Ancestry |
Sapporo Medical University School of Medicine |
Japanese Ministry of Health, Labor and Welfare |
Japan |
2020-08-01 |
|
UMIN000040656 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
200 |
DAISUKE HIRAYAMA, HIROSHI NAKASE |
2020-08-05 |
| ImmuneRACE: Immune Response Action to COVID-19 Events |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Adaptive Biotechnologies Corp |
Covance Inc |
US |
2020-04-24 |
2021-01-31 |
ADAP-006, ImmuneRACE, NCT04494893 |
Phase Not Applicable |
Recruiting |
1 |
9 Months |
1000 |
Emily A Svejnoha, BS, Emily Svejnoha, BS, Jen N Dines, MD |
2020-08-10 |
| IFN Beta-1b and Ribavirin for Covid-19 |
Coronavirus disease 19 infection |
standard care alone, interferon beta-1b plus ribavirin |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The University of Hong Kong |
Hospital Authority,Hong Kong |
Hong Kong |
2020-07-29 |
2022-08-01 |
NCT04494399, UW 20-513 |
Phase 2 Clinical |
Recruiting |
1 |
24 Months |
96 |
Ivan FN Hung, MD FRCP, Kelvin KW To, MD FRCPath, Kelvin To, MD MRCP |
2020-08-05 |
| Improving Food Pleasure and Intake of Oncology Patients Receiving Chemotherapy |
Breast tumor, Colorectal tumor, Coronavirus disease 19 infection |
standard adjuvat chemotherapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universita degli Studi di Firenze |
|
Italy |
2021-01-31 |
2022-12-31 |
ALTERTASTE, NCT04495387 |
Phase Not Applicable |
Not yet recruiting |
1 |
23 Months |
100 |
Giandomenico Roviello |
2020-08-05 |
| Effect of a Combination of Treatment of Reginmune Capsule and Immunofree Tablets in the Treatment of Mild to Moderate COVID-19 Patients |
Coronavirus disease 19 infection |
Immunofree plus Reginmune |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Nutrin GmbH |
|
India |
2020-08-07 |
2020-09-30 |
MGCTS/20/105, NCT04494204 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
4 |
1 Month |
100 |
A Gopal Rao, MD, Abhijit Munshi, Apurve Mehra, PUNEET MITTAL, Puneet Mittal, Vidyadhar G Vaidya, Vijaykumar Kamat |
2020-08-11 |
| CABS: COVID-19 cancer attitudes and behaviour study |
Cancer, Coronavirus disease 19 infection |
online survey alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry, African Ancestry |
Cardiff University |
United Kingdom Research & Innovation |
UK |
2020-06-30 |
2021-12-29 |
CABS, ISRCTN17782018 |
Phase Not Applicable |
Not yet recruiting |
2 |
18 Months |
3535 |
Ms Moriarty |
2020-08-06 |
| Neonatal complications of coronavirus disease (COVID-19) study |
Coronavirus disease 19 infection |
|
|
Newborn Infants (up to 5 months) |
University of Oxford |
National Institute for Health Research (NIHR) |
UK |
2020-03-01 |
2021-09-30 |
IRAS 282127, ISRCTN60033461 |
Phase Not Applicable |
Recruiting |
2 |
19 Months |
|
Dr Gale, Prof Jenny Kurinczuk |
2020-08-06 |
| Evaluation of the Patient-Doctor-Relationship during the COVID-19 pandemia |
Coronavirus disease 19 infection |
Survey-based Assessment alone, traditional face mask alone, transparent face mask alone |
|
|
University of Munster |
|
Germany |
2020-08-03 |
|
2020-498-f-S, DRKS00022305 |
Phase Not Applicable |
Recruiting |
1 |
|
500 |
Kristian Nikolaus Schneider |
2020-08-04 |
| A prospective (compassionate), open-label, single-center study to evaluate efficacy of remdesivir in patients with SARS-CoV-2 pneumonia |
Coronavirus disease 19 infection, Pneumonia |
remdesivir alone |
COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator |
|
Ospedale Luigi Sacco Azienda Ospedaliera Polo Universitario, Universita degli Studi di Milano |
|
Italy |
2020-02-23 |
|
|
Phase 2 Clinical |
Status not specified |
1 |
|
35 |
|
2020-08-04 |
| Mavrilimumab to Reduce Progression of Acute Respiratory Failure in COVID-19 Pneumonia and Systemic Hyper-inflammation |
Coronavirus disease 19 infection, Hypoxia, Inflammatory disease, Respiratory failure, Viral pneumonia |
mavrilimumab alone |
C-reactive protein inhibitor, Chemokine CC22 ligand inhibitor, GM-CSF receptor antagonist, Hemoglobin scavenger receptor antagonist, Metalloprotease-1 inhibitor, Metalloprotease-3 inhibitor, Small inducible cytokine A17 ligand inhibitor, VEGF gene inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Cincinnati |
Kiniksa Pharmaceuticals Ltd |
US |
2020-05-20 |
2021-05-31 |
IND 149353, NCT04492514 |
Phase 2 Clinical |
Recruiting |
1 |
12 Months |
60 |
Autumn Cresie, Kristin Hudock, MD |
2020-08-03 |
| Cyclosporine For The Treatment Of COVID-19(+) |
Coronavirus disease 19 infection |
ciclosporin, Novartis alone, standard of care alone |
Calcineurin inhibitor |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Baylor College of Medicine |
Brigham & Women's Hospital |
US |
2020-08-20 |
2025-08-20 |
H-48163, NCT04492891 |
Phase 2a Clinical |
Not yet recruiting |
1 |
60 Months |
75 |
Bryan Burt, MD, Michelle Almarez, BBA |
2020-08-03 |
| HOME-COVID-19: Mental Health Circumstances Among Healthcare Workers and General Public Under the Pandemic Situation of COVID-19 |
Coronavirus disease 19 infection, Psychiatric disorder |
online survey alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Chiang Mai University |
|
Thailand |
2020-04-21 |
|
HOME-COVID-19, TCTR20200425001 |
Phase Not Applicable |
Recruiting |
1 |
|
2500 |
Surapon Nochaiwong |
2020-08-03 |
| Effect of CRP blood test in management of COVID 19 patients |
Coronavirus disease 19 infection |
CRP test alone |
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Gujarat Cancer Society Medical college hospital and research centre |
|
India |
2020-08-05 |
|
CTRI/2020/07/026902 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Impact of CRP test in management of COVID 19 |
2020-08-03 |
| Investigational Treatments for COVID-19 in Tertiary Care Hospital of Pakistan |
Coronavirus disease 19 infection, Hypoxia, Respiratory failure, Viral pneumonia |
Fresh frozen Plasma alone, Variable regimens including Fresh frozen Plasma , convalescent Plasma , mesenchymal stem cell therapy , remdesivir , tocilizumab |
COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
United Nations International Children's Fund |
Pak Emirates Military Hospital |
Pakistan |
2020-04-01 |
2020-07-20 |
NCT04492501, SULTAN MEHMOOD KAMRAN 3 |
Phase 2 Clinical |
Completed |
1 |
3 Months |
600 |
Sultan mehmood kamran, Sumaira Irum, MIT |
2020-08-03 |
| Virtual exercise for older persons during COVID-19 pandemic |
Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression |
Exercises alone |
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Malaya |
|
Malaysia |
2020-06-01 |
2020-08-15 |
55960, NMRR-20-1629-55960 |
Phase Not Applicable |
No longer recruiting |
1 |
2 Months |
|
AMIRAH FATIN BINTI IBRAHIM, Dr Tan Maw Pin, Mrs Chong Mei Chan |
2020-08-05 |
| Impact of COVID-19 Pandemic on Genetic Services across Asia |
Coronavirus disease 19 infection |
telegenetics alone |
|
|
Genetic Counselling Society of Malaysia |
|
Malaysia |
2020-07-28 |
2020-08-31 |
55195, NMRR-20-1640-55195 |
Phase Not Applicable |
Not yet recruiting |
2 |
1 Month |
30 |
Ms Juliana Lee Mei Har, Ms Yoon Sook-Yee, Prof Dr Thong Meow Keong |
2020-08-05 |
| Detection of Antibodies to COVID-19 |
Coronavirus disease 19 infection |
VITROS 3600 system alone, VITROS 5600 system alone, VITROS CoV2T assay alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ortho Clinical Diagnostics India Private Limited |
|
India |
2020-08-03 |
|
CTRI/2020/07/026759 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
175 |
Dr Smita Sarma |
2020-08-03 |
| Vitamin-D levels in COVID-19 Patients and their relationship with other bone metabolism markers |
Coronavirus disease 19 infection, Metabolic bone disease, Vitamin D deficiency |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
All India Institute of Medical Sciences, Raipur |
|
India |
2020-08-03 |
|
181 R4, AIIMSRPR/IEC/2020/553, CTRI/2020/07/026794 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Alok Chandra Agrawal |
2020-08-05 |
| ACTT-3: Adaptive COVID-19 Treatment Trial 3 |
Coronavirus disease 19 infection |
recombinant interferon beta-1a, Merck Serono plus remdesivir |
COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, Interferon beta ligand, RNA polymerase modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Institute of Allergy and Infectious Diseases |
Merck & Co Inc |
US |
2020-08-04 |
2023-11-01 |
20-0006 ACTT-3, ACTT-3, NCT04492475 |
Phase 3 Clinical |
Recruiting |
31 |
38 Months |
1038 |
20-0006 Central Contact |
2020-08-13 |
| MICI-Covid-19: Inflammatory Bowel Disease (IBD) and Covid-19 Infection |
Coronavirus disease 19 infection |
biological testing alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hopitaux Universitaires de Strasbourg |
|
France |
2020-07-07 |
2021-01-07 |
7930, MICI-Covid-19, NCT04492267 |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
700 |
Bénédicte CARON, MD, Jean-Marie REIMUND, MD, PhD, Saïd CHAYER, PhD, HDR, Yves ARONDEL, MD |
2020-08-04 |
| An independent study to evaluate the performance of MosaiQ COVID-19 Antibody Microarray in the detection of COVID-19 antibodies in patients with COVID-19 infection |
Coronavirus disease 19 infection |
MosaiQ COVID-19 Antibody Microarray alone |
|
|
Quotient Ltd |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
500 |
|
2020-08-03 |
| GSK-3739937 First-Time-In-Human (FTIH) Study in Healthy Volunteers |
Coronavirus disease 19 infection, HIV infection |
GSK-3739937 alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
GlaxoSmithKline plc |
|
|
2020-07-31 |
2021-02-17 |
212548, NCT04493684 |
Phase 1 Clinical |
Not yet recruiting |
0 |
6 Months |
48 |
EU GSK Clinical Trials Call Center, GSK Clinical Trials, US GSK Clinical Trials Call Center |
2020-08-03 |
| A phase III clinical trial of TY-027 in patients with COVID-19 |
Coronavirus disease 19 infection |
TY-027, Tychan alone |
|
|
Tychan Pte Ltd |
|
|
|
|
|
Phase 3 Clinical |
Planned |
0 |
|
|
|
2020-08-03 |
| Affect in surgical care in children due to COVID 19 in India: a online survey of surgeons |
Coronavirus disease 19 infection |
online survey alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Chacha Nehru Bal Chikitsalya |
|
India |
2020-07-30 |
|
CTRI/2020/07/026792 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
200 |
Niyaz Khan |
2020-08-05 |
| Panchgavya Therapy in prophylaxis and as an adjuvant therapy in management of Covid 19. |
Coronavirus disease 19 infection |
Panchgavya Therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Ionisation Filtration Industries PvtLtd |
|
India |
2020-07-31 |
|
CTRI/2020/07/026793, MHC/CT/20-21/010 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
120 |
Dilip Kulkarni, Gayatri Ganu, Vivek Joshi |
2020-08-03 |
| RESIST Trial: Statin and Aspirin in SARS-CoV-2 infection |
Coronavirus disease 19 infection |
Aspirin alone, atorvastatin alone |
HMG CoA reductase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
All India Institute of Medical Sciences |
|
India |
2020-08-01 |
|
CTRI/2020/07/026791, RESIST Trial |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
800 |
Dr Deepti Siddharthan |
2020-08-05 |
| Treatment for Moderate/Severe COVID-19 in a Fragile and Vulnerable Population, Admitted to a Geriatric Hospital Unit or in a Transicional Care Center |
Coronavirus disease 19 infection, Dyspnea, Respiratory failure, Upper respiratory tract infection, Viral pneumonia |
colchicine plus prednisone |
|
Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fundacion Clinic per a la Recerca Biomédica |
|
Spain |
2020-09-30 |
2021-10-31 |
2020-002462-14, NCT04492358 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
13 Months |
144 |
Maria Joyera Rodríguez |
2020-08-03 |
| A trial to evaluate the effect of cotton face-masks and other behavioral factors on COVID-19 risk in rural Telangana |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Synergy |
|
India |
2020-08-03 |
|
CTRI/2020/07/026796 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
10000 |
Teena Desai |
2020-08-03 |
| Plasma of donors convaling by COVID-19, for the management of patients with SARS-CoV-2 illness by in Stage II (moderate) and Stage III (Severe): Multicenter, Double-blind, Randomized Study |
Coronavirus disease 19 infection |
convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Naval Medical Center at San Diego |
|
Mexico |
2020-05-18 |
|
CE/168/20 |
Phase 2 Clinical |
Recruiting |
1 |
|
50 |
NAVAL MEDICAL CENTER |
2020-08-03 |
| Clinical Trial of Treatment in Adult Patients with Pneumonia by COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
tocilizumab alone, Variable regimens including azithromycin , hydroxychloroquine , lopinavir + ritonavir |
HIV protease inhibitor |
|
American British Cowdray Medical Center |
|
Mexico |
2020-07-10 |
|
ABC-20-07 |
Phase 2 Clinical |
Recruiting |
1 |
|
36 |
PAULINA TRÁPAGA SÁNCHEZ |
2020-08-03 |
| Efficacy and safety of convalescent plasma donors by COVID-19 in patients with severe acute respiratory infection syndrome due to the SARS-COV-2 virus |
Coronavirus disease 19 infection, Respiratory distress syndrome |
convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Health Research Council of Mexican Institute of Social Security |
|
Mexico |
2020-04-22 |
|
2020-785-029 |
Phase 3 Clinical |
Recruiting |
4 |
|
400 |
|
2020-08-03 |
| TARGET-COVID: The Evaluation of Hemostasis in Hospitalized COVID-19 Patients |
Bleeding, Coronavirus disease 19 infection, Thrombosis, Viral pneumonia |
TEG6s hemostasis analyzer alone, biological sampling alone, genotyping alone, phlebotomy alone, thrombelastography alone |
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
LifeBridge Health |
Chrono-Log Corp, Haemonetics Corp, Inflammatory Markers Laboratory, Precision Biologics Inc |
US |
2020-06-30 |
2021-06-30 |
1602903, NCT04493307, TARGET-COVID |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
100 |
Ashwin Dharmadhikari, MD, Cescelle B Barbour, MSN, Cescelle Barbour, MSN, Jaime Barnes, DO, Kevin P Bliden, B.S. MBA, Paul A Gurbel, MD, kevin bliden, MBA |
2020-08-03 |
| An observational study of lying down flat on chest in treatment of corona patient who breath on their own and on oxygen therapy |
Coronavirus disease 19 infection |
Oxygen therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
New Civil Hospital, Surat |
|
India |
|
|
CTRI/2020/07/026797 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
111 |
Shweta Apatel |
2020-08-05 |
| SCCT: Singapore COVID-19 Chemosensory Tracking (SCCT) Study |
Coronavirus disease 19 infection, Respiratory disease |
home-use standardized smell and taste test alone, online software (CompuSense) alone, taste test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Clinical Nutrition Research Centre, Singapore |
National University Hospital (Singapore) Pte Ltd |
Singapore |
2020-07-23 |
2021-03-31 |
2020/00810, NCT04492904, SCCT |
Phase Not Applicable |
Recruiting |
1 |
8 Months |
5000 |
Ciaran Forde, Phd, Vicki Tan |
2020-08-03 |
| SWITCH-COVID: Switch of Renin-Angiotensin System Inhibitors in Patients With Covid-19 |
Coronavirus disease 19 infection, Hypertension |
anti-hypertensive class drug therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Sao Paulo |
|
Brazil |
2020-07-25 |
2022-02-14 |
33575220.9.0000.0068, NCT04493359, SWITCH-COVID |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
18 Months |
240 |
Bruno Caramelli, Bruno Caramelli, MD.PHD, Bruno F Caramelli, MD.PHD, Caio A Tavares, MD |
2020-08-03 |
| COVITA: Containment Measures and Eating Disorders |
Coronavirus disease 19 infection, Eating disorder |
|
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital, Montpellier |
Inserm U1061 |
France |
2020-04-01 |
2020-06-30 |
COVITA, NCT04492189, RECHMPL20_0220 |
Phase Not Applicable |
Completed |
1 |
3 Months |
40 |
Ariane SULTAN, PR |
2020-08-03 |
| In this study selenium levels would be determined in both normal volunteers as well as patients suffering from COVID-19 |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Sami Labs Ltd |
|
India |
2020-07-24 |
|
CPL/88/EPL_COVD/I/JUL/20,V2.0, CTRI/2020/07/026747 |
Phase Not Applicable |
Not yet recruiting |
2 |
|
60 |
Dr Kalpesh Shah, Dr S Krishnamoorthy, Dr Santhan Perithambi Sadagopal |
2020-08-03 |
| ACTIV: Analysis of Chronic Non-infectious Diseases Dynamics After COVID-19 Infection in Adult Patients |
Asthma, Chronic obstructive pulmonary disease, Coronavirus disease 19 infection, Diabetes mellitus, End stage renal disease, Vascular disease |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Eurasian Association of Therapists |
|
Russian Federation |
2020-06-11 |
2022-01-15 |
ACTIV, ACTIV11062020, NCT04492384 |
Phase Not Applicable |
Recruiting |
1 |
19 Months |
3500 |
Alexander Arutyunov, professor, Anastasia Rud, Anastasia Rud, master, Tamara Kriukova, Tamara Kriukova, master |
2020-08-04 |
| Using Neuromodulation to Improve Parkinson's Disease |
Coronavirus disease 19 infection, Parkinsons disease |
ThermoNeuroModulation device (Scion Neurostim Llc) alone, time-varying caloric vestibular stimulation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Wake Forest University Health Sciences, US |
Scion Neurostim Llc |
US |
2020-09-30 |
2022-09-30 |
IRB00067408, NCT04493697 |
Phase Not Applicable |
Not yet recruiting |
1 |
24 Months |
20 |
Christopher T Whitlow, MD, Richarlette C Hightower |
2020-08-03 |
| MSCT Chest in Suspected COVID-19 Patients |
Coronavirus disease 19 infection, Respiratory disease, Viral pneumonia |
RT-PCR alone, multi spiral computed tomography (MSCT) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assiut University |
|
Egypt |
2020-07-30 |
2020-10-30 |
CTCOV, NCT04492865 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
150 |
Abeer Ali, M D, Dalia Kamal, M D, Gehan S Seifeldein, M.D., Gehan S. Seifeldein, Marwa Khairallah, M D, Salwa Seif Eldein, PhD, Salwa Seif Eldin, PhD, Sara Hassanin, MD, Walaa Ali, M D |
2020-08-03 |
| To Observe Whether Isoflurane Can Treat COVID-19 Patients |
Coronavirus disease 19 infection, Viral infection, Viral pneumonia |
isoflurane alone, mechanical ventilation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Massachusetts General Hospital |
|
US |
2020-04-20 |
2020-07-20 |
2020P001048, NCT04492943 |
Phase 4 Clinical |
Recruiting |
1 |
3 Months |
40 |
Zhongcong Xie, Zhongcong Xie, M.D., Ph.D, Zhongcong Xie, PhD, MD |
2020-08-04 |
| A cohort study to evaluate the impact of COVID-19 infection on neurological integrity using Simoa NF-light kit on the Simoa HD-X Analyzer in adult patients with mild to moderate COVID-19 infection |
Coronavirus disease 19 infection, Neurological disease |
Simoa HD-X Analyzer alone, Simoa NF-light kit alone |
|
|
University Hospital Basel, University Hospital Regensburg |
|
Switzerland, Germany |
|
|
|
Phase Not Applicable |
Status not specified |
2 |
|
100 |
Jens Kuhle |
2020-08-03 |
| Knowledge Attitude and Practice of Nurses towards Hand hygiene in COVID-19 care units |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted |
Government Medical College Kannur |
|
India |
2020-08-10 |
|
CTRI/2020/07/026758 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Dr Venugopalan A K |
2020-08-04 |
| An interventional study to access the effect of Homoeopathic medicine in positive cases of COVID-19 |
Coronavirus disease 19 infection |
Eupatorium perfoliatum 30 C alone |
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Ministry of Ayush |
|
India |
2020-07-31 |
|
CTRI/2020/07/026757 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
200 |
Dr Tapan Nath, Prof Dr PK Goswami |
2020-08-04 |
| Turkish of the SARS-CoV-2 Anxiety Scale |
Anxiety disorder, Coronavirus disease 19 infection |
survey work alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Eskisehir Osmangazi University |
|
Turkey |
2020-07-24 |
2020-12-24 |
AYFER AÇIKGÖZ, DENİZ YİĞİT, DSAYIK2, ERTUĞRUL ÇOLAK, NCT04490473, ÖZLEM MUMCU |
Phase Not Applicable |
Recruiting |
1 |
5 Months |
300 |
AYFER AÇIKGÖZ, DENIZ YIGIT, DILEK SAYIK |
2020-08-04 |
| FGG: Fear learning during pandemic fear: how COVID-19 perception affects classical fear conditioning |
Coronavirus disease 19 infection, Psychiatric disorder |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs) |
Universitat des Saarlandes |
|
Germany |
2020-08-02 |
|
DRKS00022761, FGG |
Phase Not Applicable |
Recruiting |
1 |
|
120 |
Mr. M.Sc. Alexander Hauck |
2020-08-04 |
| KiTaCoviDD19: SARS-CoV-2 Surveillance in Day Care Centers (COVID-19) |
Coronavirus disease 19 infection |
|
|
|
University Hospital Carl Gustav Carus |
|
Germany |
2020-07-15 |
|
DRKS00022729, KiTaCoviDD19 |
Phase Not Applicable |
Recruiting |
1 |
|
750 |
Dr. med. Jakob Armann |
2020-08-04 |
| EMN-COVID: COVID-19 Infection and Multiple Myeloma |
Coronavirus disease 19 infection, Multiple myeloma |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
European Myeloma Network |
Fondazione EMN Italy |
Greece, Czech Republic, Austria, UK, Germany, Netherlands, Italy, Belgium |
2020-07-01 |
2021-07-31 |
EMN-COVID, EMN-COVID, NCT04492371 |
Phase Not Applicable |
Recruiting |
8 |
13 Months |
500 |
Evangelos Terpos, Prof., Gordon Cook, Prof., Hermann Einsele, Prof., Maria Krauth, Prof., Marie-Christiane Vekemans, Prof., Mario Boccadoro, Prof., Roman Hajek, Prof., Sonja Zweegman, Prof. |
2020-08-04 |
| A phase II clinical trial of TXA-127 for the potential treatment of COVID-19 infection |
Coronavirus disease 19 infection |
TXA-127 alone |
Angiotensin II receptor modulator |
|
Constant Therapeutics LLC |
|
Israel |
|
|
|
Phase 2 Clinical |
Planned |
2 |
|
|
|
2020-08-03 |
| A phase II clinical trial of TXA-127 for the potential treatment of COVID-19 infection |
Coronavirus disease 19 infection |
TXA-127 alone |
Angiotensin II receptor modulator |
|
Constant Therapeutics LLC |
|
Italy |
|
|
|
Phase 2 Clinical |
Planned |
1 |
|
|
|
2020-08-03 |
| The effect of Cognitive behaviour therapy on adult mental health during the COVID-19 pandemic |
Anxiety disorder, Coronavirus disease 19 infection, Depression |
CBT self-help guide immediately alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Curtin University, Government of Western Australia Department of Health |
|
Australia |
|
|
ACTRN12620000779976p, RES-62642 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Dr Sarah Egan |
2020-08-04 |
| CORE-THROMBOSIS: Covid-19 registry on thrombosis complications associated with hospitalization |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Johannes Gutenberg Universitat Mainz |
|
Netherlands, Germany, Belgium, Italy, UK |
2020-04-15 |
|
2020-14990-retrospektiv, CORE-THROMBOSIS, CTH C010, DRKS00022277 |
Phase Not Applicable |
Recruiting |
5 |
|
5000 |
Stavros Konstantinides |
2020-08-04 |
| Persistent lung and arterial inflammation following COVID-19 pneumonia |
Arteritis, Coronavirus disease 19 infection, Lung inflammation, Viral pneumonia |
18F-FDG PET/CT scan alone |
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sir Charles Gairdner Hospital |
|
Australia |
2020-08-03 |
|
ACTRN12620000778987p |
Phase Not Applicable |
Not yet recruiting |
3 |
|
30 |
A/Prof Roslyn Francis, Ms Elaine Campbell |
2020-08-04 |
| COVID-VTE follow-up study: COVID-VTE follow-up study |
Coronavirus disease 19 infection, Thromboembolism |
Application of the patient pathway alone |
|
|
Leiden University Medical Center |
The Netherlands Organisation for Health Research and Development, Trombosestichting Nederland |
|
2020-06-01 |
|
2020-052, COVID-VTE follow-up study, NL8787 |
Phase Not Applicable |
Recruiting |
0 |
|
400 |
Erik Klok |
2020-08-04 |
| COVID-19: Yoga for Nurses (COVID-19) |
Coronavirus disease 19 infection |
Deep Relaxation Technique alone, Yoga alone, stretch breathing excercise alone |
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Sri Devaraj Urs Academy of Higher Education and Research |
|
India |
2020-08-04 |
|
COVID-19, CTRI/2020/07/026799 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
60 |
Patil NJ |
2020-08-04 |
| A study to assess the effiacy of RTB-101 in preventing symptom development and downstream hospitalizations among positive, asymptomatic patients as well as any cohabitants of patients diagnosed with COVID-19 in community/outpatient setting |
Coronavirus disease 19 infection |
dactolisib alone |
Phosphoinositide 3-kinase inhibitor, mTOR complex 1 inhibitor, mTOR complex 2 inhibitor |
|
TrialSpark, resTORbio Inc |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-08-03 |
| A study to campare various blood investigations in COVID-19 positive patients |
Coronavirus disease 19 infection |
Inflammatory markers analysis alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Max Superspeciality Hospital Vaishali |
|
India |
2020-08-03 |
|
CTRI/2020/07/026800 |
Phase Not Applicable |
Recruiting |
1 |
|
72 |
Dhananjay Batwara |
2020-08-04 |
| EPI-COVID-POP: COVID-19 Seroprevalence Study in French Guiana |
Coronavirus disease 19 infection |
Blood sample alone |
|
Healthy volunteers accepted |
Institut Pasteur de Guyane |
Centre Hospitalier de Cayenne, Eurofins Guyane Laboratory in Rémire-Montjoly, Kourou Medical Biology Laboratory, |
French Guiana |
2020-07-15 |
2021-07-15 |
2020-048, EPI-COVID-POP, NCT04490850 |
Phase Not Applicable |
Recruiting |
5 |
12 Months |
1500 |
Claude Flamand, PhD, Didier Didier, Emmanuel Belliard, Jean-François Carod, Thierry Carage, Véronique Servas |
2020-08-04 |
| COVID-19EXO: Evaluation of safety and efficiency of method of exosome inhalation in SARS-COV-2 associated pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
EXO 1 inhalation alone, EXO 2 inhalation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Clinical Center of Cellular Technologies |
Samara Regional Clinical Hospital |
Russian Federation |
2020-07-20 |
2021-01-30 |
COVID-19 EXO, COVID-19EXO, NCT04491240 |
Phase 1/Phase 2 Clinical |
Recruiting |
1 |
6 Months |
90 |
|
2020-08-05 |
| CoV-PICS: A Virtual Post-ICU Clinic |
Coronavirus disease 19 infection |
Medical Record Review - Inpatient Treatment alone, Online Questionnaires alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Washington University School of Medicine, US |
|
US |
2020-08-01 |
2021-07-30 |
202007053, NCT04490278 |
Phase Not Applicable |
Not yet recruiting |
1 |
11 Months |
80 |
Beth Taylor, DCN, Chris Palmer, MD |
2020-08-04 |
| A prospective, open-label study to evaluate the safety and efficacy of ExoFlo in the treatment of critically ill patients with moderate to severe ARDS caused by COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
ExoFlo alone |
|
|
Christ Hospital |
|
US |
|
|
|
Phase 2 Clinical |
Status not specified |
3 |
|
|
Angel Lazo, Jr, Sascha Sengupta, Vikram Sengupta |
2020-08-03 |
| COACH: Student-delivered Telehealth Program for COVID19 Education and Health Promotion |
Coronavirus disease 19 infection |
Telehealth coaching sessions alone |
|
Healthy volunteers accepted, Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of British Columbia |
|
Canada |
2020-07-28 |
2021-07-31 |
COACH, COACH, NCT04492527 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
75 |
Brodie Sakakibara, PhD, Cam Clayton, MSc, Chelsea Pelletier, PhD, Devin Harris, MD, Jill Zwicker, PhD, Julia Schmidt, PhD, Michelle C Yang, BSc |
2020-08-05 |
| NEOSCREENCOVID: COVID-19 Infection Screening in Cancer Patients |
Coronavirus disease 19 infection |
rapid serological test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Antoine Lacassagne (Nice) |
|
France |
2020-07-21 |
2021-03-31 |
2020/23, NCT04492410, NEOSCREENCOVID |
Phase Not Applicable |
Recruiting |
1 |
8 Months |
500 |
Sandrine CHELI, PhD |
2020-08-10 |
| ketocovidiet: Eucaloric Ketogenic Diet in COVID-19 Cytokine Storm Syndrome |
Coronavirus disease 19 infection, Respiratory distress syndrome |
Ketogenic diet alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
IRCCS AOU San Martino – IST |
|
Italy |
2020-09-01 |
2021-05-30 |
KETOCOV-1, NCT04492228, ketocovidiet |
Phase Not Applicable |
Not yet recruiting |
1 |
8 Months |
100 |
Samir G Sukkar, MD |
2020-08-05 |
| Knowledge, Attitudes, and Practices Towards COVID-19 Among Health Care Professionals Among Healthcare Professionals |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Istinye Universitesi |
|
Turkey |
2020-08-01 |
2020-12-10 |
00010, NCT04492202 |
Phase Not Applicable |
Not yet recruiting |
1 |
4 Months |
200 |
Aysegul Asalioglu, Yasemin ÇIRAK, Assoc. Prof. |
2020-08-04 |
| Clearing the Fog: Is Hydroxychloroquine Effective in Reducing COVID-19 Progression (COVID-19) |
Coronavirus disease 19 infection |
hydroxychloroquine alone, Variable regimens including Panadol , vitamin C , vitamin D , zinc |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
United Nations International Children's Fund |
Pak Emirates Military Hospital |
Pakistan |
2020-04-10 |
2020-05-31 |
NCT04491994, SULTAN MEHMOOD KAMRAN 2 |
Phase 2 Clinical |
Completed |
1 |
1 Month |
500 |
Imran m Fazal, FCPS, Sultan mehmood kamran |
2020-08-04 |
| Low Dose Whole Lung Radiotherapy for Older Patients With COVID-19 Pneumonitis |
Coronavirus disease 19 infection, Viral pneumonia |
low dose whole lung radiotherapy alone |
|
Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kantonsspital Graubuenden |
|
US, Switzerland |
2020-11-30 |
2021-12-31 |
IGRG01, NCT04493294 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
2 |
13 Months |
500 |
Brigitta G Baumert, M.D.Ph.D, Nam Nguyen, Nam p Nguyen, MD |
2020-08-04 |
| Ayurveda strength and immunity enhancing protocol and immunity in health care workers : clinical trial of an Ayurveda Intervention |
Coronavirus disease 19 infection |
AYUSH Kadha alone, Anu taila alone, Chyavanprash alone, Pranayama alone, Shanshamni Vati alone, Yoga alone, rock salt alone, turmeric alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
All India Institute of Ayurveda |
|
India |
2020-07-28 |
|
CTRI/2020/07/026756 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
425 |
Dr Santosh Kumar Bhatted, Dr Tanuja Manoj Nesari |
2020-08-04 |
| Clinical severity and outcome among COVID-19 infected patients in respect to viral load and immune and inflammatory response |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
RUHS College of Medical Sciences |
|
India |
2020-07-27 |
|
CTRI/2020/07/026755 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
200 |
Sonali Sharma |
2020-08-04 |
| Evaluation of Systemic and Oral Conditions of Pregnant Women and Their Babies, With Exposure to COVID-19 Infection |
Coronavirus disease 19 infection, Periodontal disease |
|
|
Healthy volunteers accepted, Female, Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
University of Sao Paulo |
Bauru School of Dentistry |
Brazil |
2020-09-30 |
2022-12-31 |
FOBPREGNAT, NCT04492449 |
Phase Not Applicable |
Not yet recruiting |
1 |
27 Months |
260 |
|
2020-08-04 |
| Hyponatremia in covid-19 patients |
Coronavirus disease 19 infection, Hyponatremia, Inflammatory disease |
|
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Nacional Profesor Alejandro Posadas |
|
Argentina |
2020-03-07 |
2020-07-21 |
HYPONATREMIA IN COVID PATIENTS, NCT04493268 |
Phase Not Applicable |
Completed |
1 |
4 Months |
250 |
CARLOS EGHI, physician, Ladislao Diaz Ballve, GRADUATE IN KINESIOLOGY |
2020-08-04 |
| An observational, retrospective study to evaluate the impact of low dose tocilizumab on mortality rate in patients with COVID-19 related pneumonia |
Coronavirus disease 19 infection, Pneumonia, Respiratory failure |
standard of care alone, tocilizumab alone |
|
|
Montichiari hospital |
|
Italy |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
85 |
|
2020-08-03 |
| Multicenter, randomized, controlled, open-label study to study the efficacy and safety of asunercept in patients with severe COVID-19 disease |
Coronavirus disease 19 infection |
asunercept alone, standard of care alone |
CD95 antagonist |
|
Apogenix GmbH |
|
Russian Federation, Spain |
2020-07-24 |
2021-12-31 |
APG101_CD_017 |
Phase 2 Clinical |
Not yet recruiting |
8 |
17 Months |
400 |
|
2020-08-04 |
| The impact of coronavirus on mental health and well-being in Wales |
Acute stress disorder, Coronavirus disease 19 infection, Psychiatric disorder, Suicidal ideation |
online survey alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Swansea University, Wales |
|
UK |
2020-05-04 |
2020-07-13 |
ISRCTN21598625 |
Phase Not Applicable |
Completed |
2 |
2 Months |
15469 |
Prof Gray |
2020-08-05 |
| EXIT COVID-19: Extracellular Vesicle Infusion Therapy for Severe COVID-19 |
Coronavirus disease 19 infection, Hypoxia, Respiratory distress syndrome, Respiratory failure |
ExoFlo, Direct Biologics LLC alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Direct Biologics LLC |
|
US |
2020-09-01 |
2020-12-31 |
DB-001, EXIT COVID-19, NCT04493242 |
Phase 2 Clinical |
Not yet recruiting |
1 |
4 Months |
60 |
Vikram Sengupta, Principal Investigator |
2020-08-04 |
| The epidemiological characteristic of real-time covid-19 cases in north-eastern peninsular Malaysia: Jan to July 2020 |
Coronavirus disease 19 infection |
|
|
|
Jabatan Kesihatan Negeri Kelantan |
|
|
2020-07-30 |
|
NMRR-20-1624-55900 |
Phase Not Applicable |
Status not specified |
0 |
|
|
Dr HAZLIENOR BINTI MOHD HATTA |
2020-08-06 |
| Good-NIGHT COVID: Nasal washout and gargling for healthcare staff in Care Homes during the COVID-19 pandemic: The Good-NIGHT COVID pilot study |
Coronavirus disease 19 infection |
Gargling alone, Nasal lavage alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Of Southampton |
NIHR Applied Research Collaboration Wessex |
Malaysia |
|
|
ACTRN12620000737932, Good-NIGHT COVID, U1111-1252-7005 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
250 |
Dr Thomas Daniels |
2020-08-06 |
| Evaluation of the effect of chronic use of Antimalarials on the frequency of infection with the New Corona Virus 2019 (Severe Acute Respiratory Syndrome Coronavirus 2 - SARS-CoV-2) in patients with Immunomedical Rheumatic Diseases |
Connective tissue disease, Coronavirus disease 19 infection, Inflammatory disease, Myopathy, Osteoarthritis, Rheumatoid arthritis, Scleroderma, Sjoegrens syndrome, Systemic lupus erythematosus |
Chloroquine alone, Hydroxychloroquine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sociedade Brasileira de Reumatologia |
Ministério da Saúde – Departamento de Ciência e Tecnologia (MS-DECIT) |
Brazil |
|
|
30246120.3.1001.5505, RBR-9ktwx6 |
Phase Not Applicable |
Recruiting |
1 |
|
9000 |
Cláudia diniz lopes marques, Marcelo Pinheiro |
2020-08-05 |
| Status of management of surgery in Beijing during COVID-1 |
Coronavirus disease 19 infection |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Beijing Friendship Hospital, Capital Medical University |
|
|
|
|
ChiCTR2000033198 |
Phase Not Applicable |
Recruiting |
0 |
|
500 |
Kai Pang, Zhongtao Zhang |
2020-08-04 |
| Intranasal Heparin Tolerability Study |
Coronavirus disease 19 infection |
heparin sodium alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
University of Mississippi |
|
US |
2020-08-31 |
2020-09-30 |
INTRANASAL HEPARIN, NCT04490239 |
Phase 0 Clinical |
Not yet recruiting |
1 |
1 Month |
6 |
Bill Gurley, PhD, Joshua S Sharp, PhD, Joshua Sharp |
2020-08-05 |
| Characteristics and Outcomes of Gastrointestinal Manifestations of COVID-19 |
Coronavirus disease 19 infection, Gastrointestinal disease |
|
|
|
Assiut University |
|
Egypt |
2020-07-31 |
2020-09-30 |
COVID GASTRO INTESTINAL, NCT04490772 |
Phase Not Applicable |
Not yet recruiting |
1 |
2 Months |
200 |
Haidi Karam |
2020-08-04 |
| YCOVID: Rapid Diagnostic Test for COVID-19 Based on Antibody Detection |
Coronavirus disease 19 infection |
ELISA test alone, rapid diagnostic test alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Corporacion Parc Tauli |
|
Spain |
2020-06-22 |
2020-09-30 |
2020/587, NCT04490837, YCOVID |
Phase Not Applicable |
No longer recruiting |
1 |
3 Months |
3500 |
Juan Francisco Delgado de la Poza |
2020-08-04 |
| Comprehensive mental and physical health assessment and intervention studies for novel coronavirus pneumonia (COVID-19) patients |
Coronavirus disease 19 infection, Viral pneumonia |
mental and physical health assessment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Wuhan Jinyintan Hospital |
|
China |
2020-07-20 |
2022-03-31 |
ChiCTR2000035060 |
Phase Not Applicable |
Not yet recruiting |
1 |
20 Months |
2000 |
LIU YING, Liu Zhengkui, Wang Qiongya |
2020-08-05 |
| Inhalation of KELEA Excellerated Water in Covid-19 Infected Individuals |
Coronavirus disease 19 infection |
KELEA excellerated water intake alone |
|
|
Institute of Progressive Medicine |
|
US |
2020-08-10 |
2020-11-30 |
KELEA-1, NCT04490824 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
100 |
W John Martin, MD, PhD |
2020-08-12 |
| An Observational Study of Integrated Chronic Pain Management in a Community Health Center |
Coronavirus disease 19 infection, Pain |
NextGen (NextGen EHR) alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Washington University School of Medicine, US |
Logan University (US) |
US |
2018-08-01 |
2020-05-25 |
NCT04490291, RD04240531 |
Phase Not Applicable |
Completed |
1 |
21 Months |
42 |
Chrisotpher Prater |
2020-07-31 |
| AmbcoviDD19: Assessment of disease progression, infection chains and seroprevalence of Covid-19 infections in Saxony |
Coronavirus disease 19 infection |
|
|
|
University Hospital Carl Gustav Carus |
|
Germany |
2020-04-09 |
|
AmbcoviDD19, BO-EK-137042020, DRKS00022549 |
Phase Not Applicable |
Recruiting |
1 |
|
250 |
Jakob Armann |
2020-07-31 |
| Efficacy and outcomes of Lian-Hua Qing-Wen capsule in the treatment of novel coronavirus pneumonia (COVID-19): a medical records based retrospective study |
Coronavirus disease 19 infection, Viral pneumonia |
Lian-Hua Qing-Wen capsule alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
920th Hospital of Jiont Logistic Support Force,Chinese PLA |
|
China |
2020-02-04 |
|
ChiCTR2000035046 |
Phase Not Applicable |
Recruiting |
1 |
|
147 |
Liu Zhiyong, Zhang Shurong |
2020-08-03 |
| A clinical trial of allogeneic bone marrow-derived mesenchymal stem cells for treatment of adult COVID-19 patients |
Coronavirus disease 19 infection |
allogeneic bone marrow-derived mesenchymal stem cells, Stemedica Cell Technologies alone |
|
|
Promedica Inc, Stemedica Cell Technologies Inc |
|
|
|
|
|
Phase 2 Clinical |
Status not specified |
0 |
|
8 |
|
2020-07-30 |
| A phase III clinical trial of COVID-19 vaccine for potential treatment of COVID-19 infection |
Coronavirus disease 19 infection |
SARS-CoV-2 vaccine (COVID-19), Sanofi Pasteur/GlaxoSmithKline alone |
COVID19 Spike glycoprotein modulator |
|
GlaxoSmithKline plc, Sanofi SA |
|
|
2020-12-31 |
|
|
Phase 3 Clinical |
Planned |
0 |
|
|
|
2020-08-04 |
| A phase I/II clinical trial of COVID-19 vaccine for potential treatment of COVID-19 infection |
Coronavirus disease 19 infection |
SARS-CoV-2 vaccine (COVID-19), Sanofi Pasteur/GlaxoSmithKline alone |
COVID19 Spike glycoprotein modulator |
|
GlaxoSmithKline plc, Sanofi SA |
|
|
2020-09-30 |
|
|
Phase 1/Phase 2 Clinical |
Planned |
0 |
|
|
|
2020-08-04 |
| FLARE: Favipiravir +/- Lopinavir: A RCT of Early Antivirals |
Coronavirus disease 19 infection |
favipiravir alone, lopinavir + ritonavir alone, favipiravir plus lopinavir + ritonavir |
HIV protease inhibitor, RNA polymerase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
University College London, University of London |
LifeArc |
UK |
2020-08-17 |
2021-03-01 |
132084, 2020-002106-68, CTU/2020/354, FLARE, NCT04499677 |
Phase 2a Clinical |
Not yet recruiting |
1 |
6 Months |
240 |
David Lowe, FLARE Trial Team UCL CCTU |
2020-08-06 |
| PERUCONPLASMA: Evaluating the Use of Convalescent Plasma as Management of COVID-19 |
Coronavirus disease 19 infection, Respiratory insufficiency |
convalescent plasma alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universidad Peruana Cayetano Heredia |
|
Peru |
2020-08-20 |
2020-12-31 |
20997, NCT04497324, PER-016-20, PERUCONPLASMA |
Phase 2b Clinical |
Not yet recruiting |
2 |
4 Months |
100 |
Alonso Soto, MD, Fiorella Krapp Lopez, MD, MSc, Patricia Garcia Funegra, MD |
2020-08-13 |
| AP-PEDCOVID: Seroprevalence and Immunoprotection Against COVID-19 in Parisian Children |
Coronavirus disease 19 infection |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Assistance Publique Hopitaux de Paris |
|
France |
2020-04-09 |
2021-12-31 |
AP-PEDCOVID, HNECKERNM, NCT04490811 |
Phase Not Applicable |
Recruiting |
2 |
20 Months |
800 |
Isabelle Sermet-Gaudelus, Professor, Philippe Tourenne, SERMET Isabelle, Professor |
2020-07-31 |
| Convalescent plasma as treatment for COVID-19 |
Coronavirus disease 19 infection |
convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
SEGURO SOCIAL DE SALUD- ESSALUD |
|
Peru |
2020-06-01 |
|
ESSALUD-012020, PER-013-20 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
192 |
ARTURO SAGASTEGUI SOTO, AUSBERTO CHUNGA CHUNGA, CHIRISTIAN Villanueva GONZALES, IBETH MELANIA NEYRA VERA, JORGE MAGUIÑA QUISPE, LEDA YAMILEE HURTADO ROCA, PERCY SOTO BECERRA, ROGER VLADIMIR ARAUJO CASTILLO |
2020-07-31 |
| What Are the Clinical Factors Associated With a Significant Pain Reduction Following Physiotherapy in Patients With Temporomandibular Disorders |
Coronavirus disease 19 infection, Temporomandibular joint syndrome |
Physiotherapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Italian Institute Stomatologico |
The University of Birmingham |
Italy |
2019-06-14 |
2020-12-31 |
NCT03990662, PREDICTORSOUTCOMETMD2019GA |
Phase Not Applicable |
Recruiting |
1 |
18 Months |
100 |
Giacomo Asquini |
2020-08-01 |
| The Fenland COVID Study: A study to understand the progression and early signs of COVID-19 infection |
Coronavirus disease 19 infection |
smartphone app alone |
|
|
Huma |
University of Cambridge |
|
2020-07-23 |
|
The Fenland COVID Study |
Phase Not Applicable |
Recruiting |
0 |
|
|
|
2020-07-30 |
| A clinical trial of anti-SARS-CoV-2 spike protein mAb (COVID-19), Adagio Therapeutics for the potential treatment and prevention of SARS-CoV-2 infection (COVID-19) |
Coronavirus disease 19 infection |
anti-SARS-CoV-2 spike protein mAb (COVID-19), Adagio Therapeutics alone |
COVID19 Spike glycoprotein modulator |
|
Adagio Therapeutics |
|
|
2020-12-31 |
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-07-30 |
| A randomized, double-blind, placebo-controlled, pilot study to evaluate the feasibility of RTB-101 compared to placebo for COVID-19 post-exposure prophylaxis in older adults |
Coronavirus disease 19 infection |
dactolisib alone |
Phosphoinositide 3-kinase inhibitor, mTOR complex 1 inhibitor, mTOR complex 2 inhibitor |
Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
resTORbio Inc |
Harvard Medical School, National Institute on Aging, University of Connecticut Health Center |
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
60 |
|
2020-07-30 |
| Serological Surveillance for COVID-19 in Central North Carolina |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Institute Of Environmental Health Sciences |
National Institutes of Health Clinical Center |
US |
2020-08-18 |
2022-06-01 |
20-E-0143, 200143, NCT04490174 |
Phase Not Applicable |
Recruiting |
1 |
21 Months |
2500 |
Nicole Edwards, Stavros Garantziotis, M.D. |
2020-08-14 |
| Post-ICU Follow-up in Patients With Severe SARS-CoV-2 Infection (COVID-19) |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Université De Strasbourg |
|
France |
2020-07-24 |
2021-07-27 |
7890, NCT04491214 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
131 |
Walid Dr OULEHRI, PH, Walid OULEHRI |
2020-08-11 |
| SCEI: Stress Induced by the COVID-19 Pandemic and Non-confinement: Study of Anxiety Factors and Potential Effects on Immunity |
Anxiety disorder, Coronavirus disease 19 infection, Post traumatic stress disorder |
COVID-19 questionnaire alone, Experiences in Close Relationship Scale questionnaire (ECR-S) alone, Generalized Anxiety Disorder-7 (GAD 7) alone, Patient Health Questionnaire (PHQ-9) alone, Post Traumatic Stress Disorder questionnaire (PTSD-8) alone, mental health questionnaire alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire de Saint Etienne |
|
UK, France |
2020-08-31 |
2020-12-31 |
20CH129, NCT04491071, SCEI |
Phase Not Applicable |
Not yet recruiting |
2 |
4 Months |
405 |
Claude LAMBERT, MD PhD HDR, Fleur PETIT, CRA |
2020-08-12 |
| This is the comparative study between two protective boxes which can be used by the doctors while managing critical COVID 19 patients in addition to personal protective equipment |
Coronavirus disease 19 infection, Surgical procedure |
new modified aerosol box alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
All India Institute Of Medical Sciences, Rishikesh |
|
India |
2020-08-03 |
|
CTRI/2020/07/026790 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
21 |
Dr Ankit Agarwal, Dr Mohammad Hashim |
2020-08-05 |
| A clinical trial of universal SARS-CoV-2 vaccine (peptide vaccine, COVID-19), MyNEO for the potential prevention of COVID-19 |
Coronavirus disease 19 infection |
universal SARS-CoV-2 vaccine (peptide vaccine, COVID-19), MyNEO alone |
COVID19 Spike glycoprotein modulator, COVID19 envelope small membrane protein modulator, COVID19 nucleoprotein modulator, COVID19 structural glycoprotein modulator |
|
MyNEO |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-08-01 |
| HemoCov: COVID-19 Quarantine on Musculoskeletal Status in Hemophilia |
Bleeding, Coronavirus disease 19 infection, Factor IX deficiency, Factor VIII deficiency, Joint disease, Pain |
|
|
Healthy volunteers accepted, Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universidad Europea De Madrid |
|
Spain |
2020-07-01 |
2020-07-29 |
HEMOCOV, HemoCov, NCT04491318 |
Phase Not Applicable |
Recruiting |
1 |
|
27 |
Rubén Cuesta-Barriuso, PhD |
2020-07-31 |
| A single-center, cohort observational study to evaluate clinical characteristics and short-term outcome of kidney transplant patients admitted for SARS-CoV2 pneumonia |
Coronavirus disease 19 infection, Pneumonia |
anti-viral therapy alone, hydroxychloroquine alone, methylprednisolone alone, tocilizumab alone |
|
|
Azienda Ospedaliera Spedali Civili di Brescia, Universita degli Studi di Brescia |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
20 |
|
2020-07-31 |
| VESTA: Effectiveness of a Novel Respirator With Chitosan Nanoparticles |
Coronavirus disease 19 infection |
VESTA respirator alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
University of Brasilia |
Centro de Pesquisa em Biotecnologia Ltda, Hospital Regional da Asa Norte, Universidade Estadual de Campina, University Hospital of Brasilia |
Brazil |
2020-08-30 |
2021-07-31 |
32862320.0.0000.0030, NCT04490200, VESTA, VESTA TRIAL |
Phase Not Applicable |
Not yet recruiting |
1 |
11 Months |
1000 |
Aline M Toledo, PhD, Glécia V Silva Luz, PhD, Graziella A Joanitti, PhD, Henry M Peixoto, PhD, Marcella L Brettas Carneiro, PhD, Mario Fleury Rosa, PhD, Rodrigo L Carregaro, PhD, Suelia S Fleury Rosa, PhD |
2020-08-04 |
| A clinical trial of SARS-CoV-2 vaccine program (COVID-19), Avidin for the prevention of Covid-19 |
Coronavirus disease 19 infection |
SARS-CoV-2 vaccine program (COVID-19), Avidin alone |
COVID19 Spike glycoprotein modulator |
|
Avidin Biotechnology |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-08-04 |
| Umbilical Cord Tissue (UC) Derived Mesenchymal Stem Cells (MSCs) Versus Placebo to Treat Acute Pulmonary Inflammation Due to COVID-19 |
Coronavirus disease 19 infection, Hypoxia, Lung inflammation, Respiratory distress syndrome |
umbilical cord-derived mesenchymal stem cells (iv, COVID-19/lung inflammation/acute lung injury/ADRS), University of Miami alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
KCNQ2 Cure Alliance Foundation, University of Miami, University of Miami Miller School of Medicine |
|
US |
2020-08-01 |
2024-06-01 |
20200575, NCT04490486 |
Phase 1 Clinical |
Not yet recruiting |
3 |
46 Months |
21 |
Camillo Ricordi, M.D, Joshua M Hare, MD, Yvenie Desire, BS |
2020-08-04 |
| Simulation study of tracheal intubation through an aerosol-box assuming COVID-19 |
Coronavirus disease 19 infection |
AirWay Scope S-100 (Pentax) alone, Laerdal Airway Management Trainer (Laerdal Medical Japan Ltd) alone, Macintosh laryngoscope (Riester) alone, McGRATH MAC (Aircraft Medical Ltd) alone, SealGuard Evac cuffed tracheal tube (Covidien) alone, Shiley Intubation Stylet (Covidien) alone, Splash Guard CG:SGCG aerosol box alone, mask ventilation alone, tracheal intubation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tokyo Women's Medical College |
|
Japan |
2020-05-01 |
|
UMIN000040289 |
Phase Not Applicable |
No longer recruiting |
1 |
|
30 |
Idei Masafumi, Masafumi Idei |
2020-07-31 |
| On-line Neuromuscular Exercise and Education for Knee Osteoarthritis |
Coronavirus disease 19 infection, Osteoarthritis |
GLA:D exercise and education program alone, on-line NEMEX-TJR neuromuscular exercise alone, on-line education alone, on-line stretching exercise alone, on-line warm-up exercise alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Slagelse Hospital |
Region Zealand |
Denmark |
2020-06-12 |
2021-12-31 |
J.NR. 20-000013, NCT04437134, SLAGELSEH |
Phase Not Applicable |
Recruiting |
4 |
18 Months |
500 |
Pætur M Holm, PhD, Søren T Skou, Professor |
2020-07-31 |
| ALADDIN: Quality of Life and Addiction Among Hospital Night Workers |
Coronavirus disease 19 infection, Drug dependence, Post traumatic stress disorder, Psychiatric disorder |
|
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Universite Denis Diderot |
Assistance Publique Hopitaux de Paris, INSERM |
France |
2020-06-15 |
2023-06-01 |
ALADDIN, ALADDIN-QOLHOSPWORK, NCT04291534 |
Phase Not Applicable |
Not yet recruiting |
1 |
35 Months |
1800 |
Dr Martin Duracinsky |
2020-08-02 |
| Esophagogastroduodenoscopy (EGD) is an Aerosol-generating Procedure: Proof of Concept Study |
Coronavirus disease 19 infection, Gastrointestinal disease |
esophagogastroduodenoscopy alone |
|
|
Chinese University of Hong Kong |
|
Hong Kong |
2020-05-07 |
2021-01-31 |
2020.200, NCT04400734 |
Phase Not Applicable |
Recruiting |
1 |
8 Months |
60 |
Chan Shannon Melissa, Philip Chiu, FRCSEd, Shannon Chan, FRCSEd |
2020-08-02 |
| A trial to evaluate ADEXUSDx COVID-19 Antibody Test to measure the presence of SARS-CoV-2 antibodies for the diagnosis of COVID-19 |
Coronavirus disease 19 infection |
ADEXUSDx COVID-19 Antibody Test alone |
|
|
NOWDiagnostics Inc |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-07-30 |
| CMDA-SURVEY2: National Survey of the Impact of COVID-19 Pandemics |
Coronavirus disease 19 infection |
customized questionnaire alone, social software WeChat alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry |
Peking Union Medical College Hospital |
|
China |
2020-07-27 |
2020-09-27 |
CMDA-SURVEY2, CMDA-SURVEY2, NCT04491201 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
6000 |
Lei Li, M.D., Lei Li, MD |
2020-08-02 |
| Assessment of the Psychosocial Impact of the COVID-19 Pandemic on the MD Anderson Cancer Center Workforce |
Coronavirus disease 19 infection |
online questionnaire alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
MD Anderson Cancer Center |
National Cancer Institute |
US |
2020-05-18 |
2021-04-30 |
2020-0428, NCI-2020-04259, NCT04491292 |
Phase Not Applicable |
Recruiting |
1 |
11 Months |
20000 |
Priya R Bhosale, Priya R. Bhosale |
2020-08-02 |
| A Qualitative study regarding stress and coping in Front-line Health Care Doctors at a tertiary-care hospital |
Acute stress disorder, Coronavirus disease 19 infection, Psychiatric disorder |
depth interview alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
B. J. Medical College, Pune |
|
India |
2020-08-17 |
|
CTRI/2020/07/026788 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
20 |
Dr Ivan Stanley Netto |
2020-08-04 |
| Global Assessment of Acute and Chronic Kidney Disease Incidence and Outcomes in Patients With COVID-19 Infection |
Coronavirus disease 19 infection, End stage renal disease, Renal disease, Renal injury |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of California San Diego |
|
Chile, India, Canada, UK, Bolivia, US |
2020-05-05 |
2023-03-31 |
000295, NCT04491227 |
Phase Not Applicable |
Recruiting |
12 |
34 Months |
2000 |
Ravindra L Mehta |
2020-08-01 |
| R4VaD: Understanding cognitive decline after stroke and the impact of COVID-19 |
Cognitive disorder, Coronavirus disease 19 infection, Stroke, Vascular dementia |
Blood analysis alone, Routine bran imaging (CT or MRI) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Academic and Clinical Centre Office for Research and Development [ACCORD], UK |
Alzheimers Society, British Heart Foundation, The Stroke Association, United Kingdom |
UK |
2018-07-01 |
2023-06-30 |
AC18001, ISRCTN18274006, R4VaD |
Phase Not Applicable |
Recruiting |
10 |
60 Months |
2000 |
Prof Wardlaw |
2020-08-06 |
| INHALE: Inhale work package 3 - rapid versus standard testing to diagnose lung infections in intensive care, including COVID-19 observational sub-study |
Coronavirus disease 19 infection, Lower respiratory tract infection, Viral pneumonia |
BioFire FilmArray alone, standard care alone |
|
|
University College London |
NIHR Central Commissioning Facility |
UK |
2018-10-01 |
2021-06-30 |
41211, INHALE, ISRCTN16483855 |
Phase Not Applicable |
Recruiting |
12 |
33 Months |
466 |
Dr Enne |
2020-08-03 |
| postcorona: Postcorona care |
Coronavirus disease 19 infection, Heart disease, Inflammatory disease, Lung disease, Psychotic disorder, Pulmonary fibrosis |
|
|
|
Leiden University Medical Center |
|
Netherlands |
2020-07-13 |
2020-12-22 |
NL8775, postcorona |
Phase Not Applicable |
Recruiting |
1 |
5 Months |
90 |
Geert Groeneveld |
2020-07-31 |
| A clinical trial to study the effects of an Ayurvedic medicine, Haldi 30 (Turmeric extract) drops in patients with Corona virus infection |
Coronavirus disease 19 infection |
Haldi 30 alone, Standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sahyadri Hospitals |
|
India |
2020-08-03 |
|
CTRI/2020/07/026841 |
Phase 2 Clinical |
Not yet recruiting |
2 |
|
260 |
Dr Sarang Phadke |
2020-08-02 |
| Determination of dandelion capsule on patient with COVID-19 virus |
Coronavirus disease 19 infection |
Variable regimens including Dandelherb (Booali Daro Pharmaceutical Factory) , dexamethasone , interferon beta-1b , remdesivir |
COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Ghoum University of Medical Sciences |
|
Iran |
2020-07-26 |
|
IR.MUQ.REC.1399.148, IRCT20180513039641N2 |
Phase 3 Clinical |
Recruiting |
1 |
|
80 |
Ehsan Sharifipour, Hoda Abolhasani, Reihaneh Tabaraie, hoda Abolhasani |
2020-08-03 |
| Evaluating the effects of intravenous immunoglobulin (IVIG) in COVID-19 patients |
Coronavirus disease 19 infection |
Variable regimens including IVIG (Biotest) , hydroxychloroquine (Tehran Daroo) , lopinavir + ritonavir (Hetero Labs Limited) |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Shaheed Beheshti Medical University |
|
Iran |
2020-07-09 |
|
IR.SBMU.NRITLD.REC.1399.143, IRCT20151227025726N20 |
Phase 2/Phase 3 Clinical |
No longer recruiting |
1 |
|
80 |
Afshin Zarghi, Farzaneh Dastan, Payam Tabarsi, Zahra Mirshafiei Langari |
2020-08-12 |
| Safety and Efficacy of EDP-1815 in the Treatment of Patients Hospitalized With COVID-19 Infection |
Coronavirus disease 19 infection |
EDP-1815 alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Evelo Biosciences Inc, Robert Wood Johnson University Hospital, Rutgers University |
|
US |
2020-08-07 |
2020-12-21 |
EDP1815-205, NCT04488575 |
Phase 2 Clinical |
Not yet recruiting |
4 |
4 Months |
60 |
Daniela Walker, Deborah McCloskey, Douglas Maslin, MD, Keith Guevarra, MD, Randall Teeter, Reynold A. Panettieri, Jr., M.D |
2020-07-31 |
| PERSO-COVID: Medical and Serological Follow-up of the Staff of the Paris Saint-Joseph Hospital Group Infected With Severe Acute Respiratory Syndrome Coronavirus 2. |
Coronavirus disease 19 infection |
Serology test follow-up alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Groupe Hospitalier Paris Saint-Joseph |
|
France |
2020-07-01 |
2021-12-31 |
NCT04488484, PERSO-COVID, PERSO-COVID |
Phase Not Applicable |
No longer recruiting |
1 |
18 Months |
450 |
|
2020-08-13 |
| STAND UP to SARS-CoV-2 (COVID-19): Using Behavioural Economics to Reduce Sedentary Behaviour in At-home Office Workers |
Coronavirus disease 19 infection |
Long-List Choice Group alone, No Choice Group alone, Short List Choice Group alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Western Ontario |
Duke University |
Canada |
2020-09-30 |
2020-12-31 |
116127, NCT04488796 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
135 |
Kirsten Dillon, MA, Madison S Hiemstra, BSc, Marc Mitchell, PhD, Marc Mittchell, PhD |
2020-08-08 |
| COVAP: Pathogens Involved in Secondary Infections During Severe Forms of Covid-19 Pneumonia |
Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Groupe Hospitalier Paris Saint-Joseph |
Centre Hospitalier Victor Dupouy |
France |
2020-05-06 |
2020-11-30 |
COVAP, COVAP, NCT04488510 |
Phase Not Applicable |
No longer recruiting |
1 |
6 Months |
150 |
|
2020-08-04 |
| DECOR-19: Delayed Colorectal Cancer Care During Coronavirus Disease (COVID-19) Pandemic |
Colorectal tumor, Coronavirus disease 19 infection |
|
|
|
Treviso Regional Hospital |
Universita degli Studi di Roma La Sapienza, Universita' Degli Studi "Magna Graecia" Di Catanzaro |
Italy |
2020-05-20 |
2020-06-10 |
DECOR-19, NCT04488549, TREVISO |
Phase Not Applicable |
Completed |
1 |
|
1051 |
Gaetano Gallo, Gian Luca Di Tanna |
2020-07-30 |
| Can Remote Photoplethysmography Be Used for Contactless Vital Sign Acquisition in a Healthcare Setting? A Prospective, Comparative Study |
Coronavirus disease 19 infection |
Masimo Radical 7 alone, Welch Allyn Connex Vital Signs Monitor alone, Welch Allyn Vital Signs Monitor alone, remote photoplethysmography (rPPG) vital sign acquisition alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Lady Davis Institute |
Carebook Technologies Inc |
Canada |
2020-08-01 |
2020-11-30 |
2021-2376, NCT04489407 |
Phase Not Applicable |
Not yet recruiting |
1 |
4 Months |
350 |
Noura Hassan, Noura Hassan, MD, MPH |
2020-07-29 |
| Study of skin, hair and nail changes after COVID 19 illness |
Coronavirus disease 19 infection, Dermatological disease |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Gujarat Cancer Society Medical college hospital and research centre |
|
India |
2020-08-24 |
|
CTRI/2020/07/026821 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
500 |
Dr Nayan H Patel |
2020-08-03 |
| BET: A NIAID-sponsored Big Effect trial (BET) to assess the combination of lenzilumab and remdesivir on treatment outcomes versus placebo and remdesivir in hospitalized COVID-19 patients |
Coronavirus disease 19 infection |
lenzilumab plus remdesivir |
COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, GM-CSF ligand inhibitor, Immunoglobulin G1 modulator, Immunoglobulin kappa modulator, RNA polymerase modulator |
|
Humanigen Inc, National Institute of Allergy and Infectious Diseases |
|
|
|
|
BET |
Phase Not Applicable |
Status not specified |
0 |
|
|
|
2020-07-29 |
| Curcumin for COVID-19 Pre Exposure Prophylaxis |
Coronavirus disease 19 infection |
curcumin alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
All India Institute Of Medical Sciences, Rishikesh |
|
India |
2020-08-09 |
|
CTRI/2020/07/026820 |
Phase 4 Clinical |
Not yet recruiting |
1 |
|
200 |
Rohit Walia |
2020-07-30 |
| Comparison of two different types of simple non-invasive oxygen therapy devices in coronavirus lung infection |
Coronavirus disease 19 infection, Lung infection, Respiratory failure, Viral pneumonia |
High Flow Nasal Oxygen alone, Optiflow alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
All India Institute of Medical Sciences |
|
India |
2020-07-27 |
|
CTRI/2020/07/026835 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
100 |
Dalim Kumar Baidya |
2020-07-30 |
| A clinical trial of anti-coronavirus vaccine,State Research Center of Virology and Biotechnology VECTOR for the treatment of COVID-19 |
Coronavirus disease 19 infection |
anti-coronavirus vaccine,State Research Center of Virology and Biotechnology VECTOR alone |
|
|
State Research Center of Virology and Biotechnology VECTOR |
|
|
|
|
|
Phase Not Applicable |
Not yet recruiting |
0 |
|
|
|
2020-07-29 |
| Survival and 30-days Hospital Outcome in COVID-19 Patients in Upper Egypt |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Assiut University |
|
Egypt |
2020-03-15 |
2020-07-01 |
ASSIUTU17, NCT04488588 |
Phase Not Applicable |
Completed |
2 |
3 Months |
1064 |
Aliae Mohamed-Hussein, MD |
2020-07-30 |
| Open Skies: Use of new technology for rapid detection of SARS-CoV2 |
Coronavirus disease 19 infection |
NAOR platform alone, Terasystem Breath Analyser test alone, VIRION test alone, Voice Pattern test alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry |
Defence Research & Development Organisation |
Defence Institute of Physiology and Allied Sciences (DIPAS) |
India |
2020-08-05 |
|
CTRI/2020/07/026843, Open Skies, Open Skies |
Phase Not Applicable |
Recruiting |
4 |
|
10000 |
Dr Ambuj Garg, Dr Anil Gurtoo, Dr Desh Deepak, Dr Naresh Kumar, Dr Reena Mariya |
2020-07-31 |
| Nimesulide in COVID-19 infection |
Coronavirus disease 19 infection, Viral pneumonia |
Variable regimens including azithromycin , enoxaparin sodium , nimesulide , sucralfate |
Cyclooxygenase 2 inhibitor, Low molecular weight heparin |
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shaheed Zulfiqar Ali Bhutto Medical University Islamabad |
|
Iran |
2020-07-28 |
|
IRCT20200723048178N1, No.F.1-1//2015/ERB/SZABMU/605 |
Phase 2 Clinical |
Recruiting |
1 |
|
60 |
Ahmed Farhan |
2020-07-30 |
| REaCHing to you with listening ears: A friendly telephonic interaction program for the DDU-GKY members |
Coronavirus disease 19 infection |
Assertive linkage with community resources alone, Proactive Engagement and Crisis Intervention alone, Problem-solving oriented supportive therapy alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs) |
Rajagiri college of Social Sciences |
UK India Education Research Initiative (UKIERI) |
India |
2020-08-07 |
|
CTRI/2020/07/026834 |
Phase Not Applicable |
Not yet recruiting |
26 |
|
1480 |
Dr Saju M D |
2020-07-30 |
| Artificial intelligence and machine learning for Covid 19 |
Coronavirus disease 19 infection |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Visvesvaraya Technological University (VTU) |
|
India |
2020-07-13 |
|
CTRI/2020/07/026832 |
Phase 1 Clinical |
Not yet recruiting |
1 |
|
100 |
Dr DwajaniS, Dr Mukesh PR |
2020-07-30 |
| Sildenafil in COVID-19 |
Coronavirus disease 19 infection, Ischemia |
sildenafil alone |
PDE 5 inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universidad Andres Bello |
Hospital Naval Almirante Nef |
Chile |
2020-08-31 |
2021-03-31 |
NCT04489446, UNAB-003 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
7 Months |
40 |
Cesar Reyes, MD, Dominique Boisier, MD, Eduardo Labarca, MD, Felipe M Martinez, MD, MSc, Felipe Martinez, MD, MSc, Jaime Vidal, MD, Jorge Vega, MD, Mario Santamarina, MD, Miguel Gutierrez, MD, Monica Gutierrez, MD, Nicole Retamal, Roberto Contreras, MD, Sebastian Ahumada, MD |
2020-07-31 |
| COVID-19: Attitude Toward Quarantine |
Coronavirus disease 19 infection |
|
|
|
Taibah University |
|
Saudi Arabia |
2020-07-15 |
2020-08-15 |
55834, NMRR-20-1574-55834 |
Phase Not Applicable |
Status not specified |
1 |
1 Month |
|
Noordin othman, Suhana Jawahir |
2020-07-30 |
| Hydroxychloroquine for COVID-19 |
Coronavirus disease 19 infection |
hydroxychloroquine alone |
|
|
National Institutes of Health Malaysia |
|
Malaysia |
2020-08-03 |
2020-09-03 |
54669, NMRR-20-1593-54669 |
Phase Not Applicable |
Status not specified |
1 |
1 Month |
|
dr Nor Asiah Muhamad |
2020-07-30 |
| A study to assess the effectiveness of Ayurvedic formulation Guduchi Ghan vati in Covid-19 cases |
Coronavirus disease 19 infection |
Guduchi Ghan Vati alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ministry of Ayush |
|
India |
2020-07-28 |
|
CTRI/2020/07/026840 |
Phase 2 Clinical |
Recruiting |
1 |
|
30 |
Dr Nitin Ujjaliya, Dr Vivek Khare, Prof Umesh Shukla |
2020-08-02 |
| Facts on Bear Bile Use in Coronavirus Disease 2019 (COVID-19) |
Coronavirus disease 19 infection |
Bear Bile alone |
|
|
Institute For Medical Research (Inc In Malaysia) |
|
Malaysia |
2020-04-01 |
2020-06-01 |
55957, NMRR-20-1604-55957 |
Phase Not Applicable |
Status not specified |
1 |
2 Months |
|
Ms. Lim Xin Yi, Terence Tan Yew Chin |
2020-07-31 |
| LUS: lung ultrasound |
Coronavirus disease 19 infection |
ultrasound alone |
|
|
Hospital Sungai Buloh |
|
Malaysia |
2020-07-27 |
2020-12-31 |
55711, NMRR-20-1599-55711 |
Phase Not Applicable |
Status not specified |
1 |
5 Months |
|
Dr ELISA AUDREY EDDIE, Dr Mahathar Abdul Wahab |
2020-08-02 |
| Antibody, RT-PCR, COVID-19 |
Coronavirus disease 19 infection |
RT-PCR alone |
|
|
Hospital Sungai Buloh |
|
Malaysia |
2020-07-31 |
2021-07-30 |
55832, NMRR-20-1598-55832 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
|
DR THARMINI A/P RAVI, Dr Suresh Kumar |
2020-07-31 |
| A phase II/III clinical trial of CodaVax-COVID for the prevention of Covid-19 |
Coronavirus disease 19 infection |
CodaVax-COVID alone |
|
|
Codagenix Inc, Serum Institute of India Ltd |
hVIVO plc |
|
|
|
|
Phase 2/Phase 3 Clinical |
Planned |
0 |
|
|
|
2020-07-29 |
| A trial to evaluate rigosertib for the treatment of patients with COVID-19 disease |
Coronavirus disease 19 infection |
rigosertib sodium (iv, MDS/solid tumors), Onconova/SymBio alone |
AKT protein kinase inhibitor, BCL2L11 gene stimulator, Cyclin D1 inhibitor, Cyclin-dependent kinase-1 inhibitor, Jun N terminal kinase modulator, MAP kinase inhibitor, Phosphoinositide 3-kinase inhibitor, Polo-like kinase 1 inhibitor, Raf protein kinase inhibitor |
|
Onconova Therapeutics Inc |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-07-29 |
| HOMECOMIN': Home Monitoring and Evaluation After Admission for COVID-19 in the Netherlands |
Coronavirus disease 19 infection, Pulmonary fibrosis |
spirometer (Spirobank Smart) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Erasmus University Medical Center Rotterdam |
Dutch Society of Physicians for Pulmonology and Tuberculosis, Leiden University Medical Center, VU University Medical Center |
Netherlands |
2020-05-08 |
2021-12-31 |
HOMECOMIN', MEC-2020-0318, NCT04488562 |
Phase Not Applicable |
Recruiting |
3 |
19 Months |
150 |
C.C. Moor, drs, Cintha Klop, E.J. Nossent, Esther van der Kaay, G Nakshbandi, G. Nakshbandi, drs, Gizal Nakshbandi, drs, J.J.M. Geelhoed, dr, M.S. Wijsenbeek, dr |
2020-07-30 |
| Impact of Isolation in Patients With IBD During the COVID-19 Crisis |
Coronavirus disease 19 infection, Inflammatory bowel disease |
|
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sheffield Teaching Hospitals NHS Foundation Trust |
|
UK |
2020-06-30 |
2022-06-30 |
NCT04488471, STH21414 |
Phase Not Applicable |
Recruiting |
1 |
24 Months |
232 |
Alan Lobo, MD, Luke Barron, MSc |
2020-07-30 |
| Clinical trial of Annual SZ drug in Covid-19 |
Coronavirus disease 19 infection |
Anval SZ plus azithromycin |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Shaheed Beheshti Medical University |
|
Iran |
2020-06-09 |
|
IR.SBMU.RETECH.REC.1399.158, IRCT20200607047682N1 |
Phase 2/Phase 3 Clinical |
No longer recruiting |
1 |
|
60 |
Afshin Zarghi, Hamid Chegini, Mohammad Farhbakhsh, Zuhair Sarraf |
2020-07-30 |
| Evaluation of the efficacy and safety of inhaled magnesium sulfate in combination with standard treatment in Covid-19 patients |
Coronavirus disease 19 infection |
magnesium sulfate alone, standard treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shaheed Beheshti Medical University |
|
Iran |
2020-07-27 |
|
IR.SBMU.NRITLD.REC.1399.148, IRCT20191211045691N1 |
Phase 3 Clinical |
Recruiting |
1 |
|
100 |
Guitti Pourdowlat, Seyed Ruhollah Mousavinasab, Parissa Farnia |
2020-07-30 |
| Tele-health Enabled Clinical Trial for COVID19 |
Coronavirus disease 19 infection, Immune disorder |
Doctella device alone, cholecalciferol alone, telehealth monitoring alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospitals of Cleveland |
Northwestern University |
US |
2020-08-01 |
2021-08-01 |
NCT04489628, STUDY20200461 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
12 Months |
110 |
Amanda Davies, Kevin Cooper, MD, Kurt Lu, MD, Lyndsey O'Hara, BSN, Wesley Yu, MD |
2020-08-04 |
| CoronaKids: CoronaKids - Epidemiological data acquisition SARS-CoV2/Covid-19 |
Coronavirus disease 19 infection |
epidemiological data analysis alone |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Univ Witten / Herdecke |
|
Germany |
2020-03-27 |
|
61/2020, CoronaKids, DRKS00021229 |
Phase Not Applicable |
Recruiting |
1 |
|
900 |
Stefan Wirth |
2020-07-30 |
| CCHROMO: COVID19 Chronic Morbidity: Follow-up of patients with COVID19 and non-COVID19 pneumonia with respect to clinical status, pulmonary function and radiologic findings |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universitätsklinikum Frankfurt Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie |
Hannover Medical School |
Germany |
2020-07-27 |
|
20-748, CCHROMO, DRKS00022475 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
500 |
Gernot Rohde |
2020-08-06 |
| CovPall: Improving palliative care for people affected by the COVID-19 pandemic by sharing learning - the national and international response |
Coronavirus disease 19 infection |
palliative care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
King's College London |
Cicely Saunders International, Kings College Hospital NHS Trust, National Institute for Health Research (NIHR) |
India, Brazil, South Africa, Netherlands, Portugal, Switzerland, Argentina, Australia, Ireland, Canada, UK |
2020-04-01 |
2021-04-24 |
CovPall, ISRCTN16561225, LRS-19/20-18541, IRAS 282824 |
Phase Not Applicable |
Recruiting |
13 |
12 Months |
|
Miss Cripps |
2020-07-30 |
| Study of Shreepad Shree Vallabh SSV Formulation in management of COVID-19 |
Coronavirus disease 19 infection |
SSV Formulation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
SSV Phytopharmaceuticals |
|
India |
2020-08-05 |
|
CTRI/2020/07/026839, SSV-SF-07/2020 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
150 |
Dr Sagar Mandlik, Dr Yogesh Dound |
2020-07-30 |
| PREDISCAN: Predicting the Progression to Chronic Fibrosis of Lung Lesions Related to Covid-19 Infection From Chest CT Images |
Coronavirus disease 19 infection, Pulmonary fibrosis, Viral pneumonia |
Chest CT scan alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Association Marie Lannelongue |
|
France |
2020-06-08 |
2021-11-08 |
2020-A01322-37, NCT04483752, PREDISCAN |
Phase Not Applicable |
Recruiting |
3 |
17 Months |
100 |
CAROLINE CARAMELLA, MD, Corinne Institut Gustave Roussy (IGR), MD, Marie De Torcy |
2020-07-30 |
| Antibody response to COVID-19 in health care workers |
Coronavirus disease 19 infection |
LIAISON SARS-CoV-2 S1/S2 IgG test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
DiaSorin Healthcare India Private Limited, Ortho Clinical Diagnostics India Private Limited |
|
India |
2020-08-04 |
|
|
Phase Not Applicable |
Not yet recruiting |
1 |
|
|
Dr Smita Sarma |
2020-07-29 |
| Effect of COVID - 19 pandemic researchers |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Manipal Academy of Higher Education |
|
India |
2020-08-10 |
|
CTRI/2020/07/026836 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1850 |
Elsa Sanatombi Devi |
2020-07-30 |
| Encouraging behavior to reduce the spread of COVID-19 |
Coronavirus disease 19 infection |
Impact Others, Cooperative Linear Production (IOCLP) message alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Yale University |
|
US |
2020-05-01 |
2020-07-24 |
1312013102, ISRCTN17896927 |
Phase Not Applicable |
Completed |
2 |
2 Months |
3000 |
Prof Huber |
2020-07-30 |
| N-terminal Pro B-type Natriuretic Peptide and Vitamin D Levels as Prognostic Markers in COVID-19 Pneumonia |
Coronavirus disease 19 infection, Hypoxia, Respiratory failure, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cairo University |
Kasr El Aini Hospital |
Egypt |
2020-07-01 |
2021-01-01 |
2020-7-1, NCT04487951 |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
100 |
Akram Abdelbary, Prof., Noha A. Radwan, Noha A. Radwan, Lecturer, Noha A. Radwan, Lecturer of Chemical pathology, Noha Radwan, Lecturer, Yasmine Elshiwy, Ass. Prof. |
2020-08-05 |
| Complementary Intervention for COVID-19 |
Coronavirus disease 19 infection |
conventional therapy alone, Boswellia Serrata gum plus Licorice extract |
|
Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Assiut University |
|
Egypt |
2020-01-01 |
2021-01-31 |
0925-0586, NCT04487964 |
Phase Not Applicable |
Recruiting |
1 |
13 Months |
70 |
Adel A. Gomaa, Ph.D., Adel Gomaa, Ph.D., Hamdy S Mohamed, MD, Mostafa Hamdy, Ph.D. |
2020-07-30 |
| SARS-CoV2 (COVID-19) Seroepidemiological Transplanted Subjects (Kidney, Kidney-pancreas, Pancreas, Langerhans Islets) |
Coronavirus disease 19 infection, Kidney transplantation, Pancreas transplantation |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
IRCCS San Raffaele |
|
Italy |
2020-07-15 |
2021-01-15 |
COVID-SIERO TRAPIANTI, NCT04487197 |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
300 |
Antonio Secchi, MD, Federica Pazzi, Paola Maffi, Rossana Caldara |
2020-08-05 |
| A Phase I, Prospective, Open-labeled Study to Evaluate the Safety and Immunogenicity of MVC-COV1901 |
Coronavirus disease 19 infection |
MVC-COV1901 alone |
COVID19 Spike glycoprotein modulator, TLR-9 agonist |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Medigen Vaccine Biologics Corp |
|
Taiwan |
2020-09-01 |
2021-12-31 |
CT-COV-11, NCT04487210 |
Phase 1 Clinical |
Not yet recruiting |
1 |
16 Months |
45 |
Criss Cheng, Szu-Min Hsieh, MD |
2020-07-30 |
| Respiratory Mechanics and Gas Exchange Characteristics in Patient With SARS-CoV-2 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
positive end-expiratory pressure therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sanatorio Anchorena San Martin |
|
Argentina |
2020-07-01 |
2020-10-20 |
10.2020, NCT04486729 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
15 |
Javier H Dorado, PT, Joaquin Pérez, PT, Matias Accoce |
2020-07-30 |
| Exploring the Impact of a Sleep App on Sleep Quality |
Coronavirus disease 19 infection, Insomnia |
sleep app (Pro version) alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University College London |
University of California Los Angeles |
UK |
2020-02-13 |
2020-08-15 |
NCT04487483, SLEEPAPPEVALUATION |
Phase Not Applicable |
No longer recruiting |
1 |
6 Months |
101 |
Abi Fisher |
2020-08-12 |
| DAMPEN-CI: Duvelisib Ameliorates Manifestations of Pneumonia in Established Novel Coronavirus Infection (COVID-19) |
Coronavirus disease 19 infection, Inflammatory disease, Viral pneumonia |
duvelisib alone |
Phosphoinositide-3 kinase delta inhibitor, Phosphoinositide-3 kinase gamma inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Emory University |
University of Pennsylvania, Verastem Oncology |
US |
2020-08-31 |
2022-02-28 |
DAMPEN-CI, NCT04487886, STUDY00000701 |
Phase 2 Clinical |
Not yet recruiting |
3 |
18 Months |
80 |
Aneesh Mehta, MD, Edmund Waller, MD, PhD |
2020-07-29 |
| Hematology and Clinical Picture in Pediatric COVID-19 Infection |
Coronavirus disease 19 infection, Hematological disease |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Benha University |
|
Egypt |
2020-07-26 |
2020-08-21 |
NCT04487119, RC 6-7-2020 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
30 |
Effat H Assar, MD, Rana A Khashaba, MD, Shaimaa R Abdelmaksoud, MD |
2020-07-29 |
| PLEXIT: Therapeutic Plasma Exchange (TPE) for COVID-19 Cytokine Release Storm (CRS) |
Coronavirus disease 19 infection, Hypoxia, Respiratory distress syndrome, Respiratory failure, Sepsis, Viral pneumonia |
COBE Spectra Apheresis machine version 7 (TERUMO BCT) alone, anticoagulation therapy alone, corticosteroids therapy alone, ulcer prophylaxis alone, Variable regimens including Fresh frozen Plasma (FFP) , aspirin , methylprednisolone |
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
United Nations International Children's Fund |
Pak Emirates Military Hospital |
Pakistan |
2020-04-01 |
2020-06-30 |
NCT04485169, PLEXIT, SULTAN MEHMOOD KAMRAN |
Phase 2 Clinical |
Completed |
1 |
3 Months |
280 |
Imran m Fazal, FCPS, Sultan mehmood kamran |
2020-07-29 |
| A pan-India phase IV trial of itolizumab in COVID-19 patients |
Coronavirus disease 19 infection |
itolizumab alone |
T-cell differentiation antigen CD6 inhibitor |
|
Biocon Ltd |
|
|
|
|
|
Phase 4 Clinical |
Planned |
0 |
|
200 |
|
2020-07-30 |
| FERTICOVID: Presence of SARS-CoV-2 in Semen: Impact on Fertility Preservation in Male Oncological Patients? |
Cancer, Coronavirus disease 19 infection |
RT- qPCR alone, nasopharyngeal swab test alone, serological test alone |
|
Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Clermont-Ferrand |
Biomedicine Agency |
France |
2020-07-10 |
2021-07-31 |
2020-A01409-30, FERTICOVID, NCT04487639, RNI 2020 BRUGNON |
Phase Not Applicable |
Recruiting |
15 |
12 Months |
250 |
Amélie BREBION, PharmD, Anne MAYEUR, MD, PhD, Anne-Sophie CANEPA, MD, Arthur LUTON, MD, Audrey MIRAND, PharmD, PhD, Aurélie RIVES-FERAILLE, MD, Badria BENNANI SMIRES, MD, Béatrice DELEPINE, MD, Carole Carole, MD, Caroline AIMONE VIANNA, MD, Catherine DILIGENT, MD, PhD, Catherine GUILLEMAIN, MD, Catherine PATRAT, MD, Charlotte DUPONT, MD, PhD, Charlotte MAUROY, MD, Cécile GREZE, MD, Cécile HENQUELL, PharmD, PhD, Céline BOUILLON, MD, Céline BRUNO, MD, Céline CHALAS, MD, Diane RIVET-DANON, MD, Elsa LABRUNE, MD, Emmanuel DULIOUST, MD, PhD, Fanny JUMEAU, MD, Florence BOITRELLE, MD, PhD, Florence BRUGNON, MD, PhD, Florence EUSTACHE, MD, Hanae Pons-Rejraji, PhD, Isabelle KOSCINSKI, MD, PhD, Isabelle LICHTBLAU, MD, Jacqueline LORNAGE, MD, PhD, Jacqueline SAIAS-MAGNAN, MD, Jessika MOREAU, MD, Julie BARBERET, MD, Julien BESSONAT, MD, Laetitia LADUREAU-FRITSCH, MD, Laure CHAPUT, PD, Laëtitia HESTERS, PharmD, Lise LACLAUTRE, Pharm D, Louis BUJAN, MD, Marion BENDAYAN, MD, Marius TELETIN, MD, PhD, Myriam DAUDIN, MD, Nathalie MOINARD, MD, Nathalie RIVES, MD, Nelly FRYDMAN, PharmD, PhD, Olivier BINOIS, MD, Patricia FAUQUE, MD, PhD, Pierre DI PIZIO, MD, Rachel LEVY, MD, Rahaf HAJ HAMID, MD, Sandrine GISCARD D'ESTAING, MD, PhD, Sara KOUIRI, MD, Solmaz SARANDI, MD, Solène VORILHON, MD, PhD, Sylvianne HENNEBICQU, MD, PhD, Thomas BOUEILH, MD, Virginie BARRAUD-LANGE, MD, PhD, Véronique DROUINEAUD, MD |
2020-07-29 |
| Impact Nerium Oleander on Symptoms and Mortality: A Feasibility Study |
Coronavirus disease 19 infection |
Nerium oleander proprietary extract alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
HealthQuilt |
Baylor College of Medicine, Texas A&M University System, The Hildebrand Fund at the Greater Houston Community Foundation, The Schull Institute, University of Maryland College Park, University of Texas Health Science Center Houston |
US |
2020-05-20 |
2020-09-01 |
052020, NCT04486144 |
Phase 2 Clinical |
Recruiting |
1 |
3 Months |
100 |
Kim Dunn, MD, Ph.D. |
2020-07-29 |
| Online 1-day CBT-based Workshops for PPD |
Coronavirus disease 19 infection, Postnatal depression |
cognitive behavioural therapy based workshop alone, standard postnatal care alone |
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
McMaster University |
|
Canada |
2020-04-20 |
2020-12-31 |
NCT04485000, ONLINE1DAYCBT |
Phase Not Applicable |
Recruiting |
1 |
8 Months |
388 |
Ryan Van Lieshout, MD, PhD |
2020-07-29 |
| Thymalfasin (Thymosin Alpha 1) to Treat COVID-19 Infection (Ta1) |
Coronavirus disease 19 infection, Lymphocytopenia |
standard of care alone, thymalfasin alone |
Thymosin receptor agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Rhode Island Hospital |
|
US |
2020-07-31 |
2021-04-30 |
NCT04487444, SCN-16130571-2 |
Phase 2 Clinical |
Not yet recruiting |
1 |
9 Months |
80 |
Eleftherios Mylonakis, MD PhD FIDSA, Fadi Shehadeh |
2020-07-30 |
| I-SPY COVID-19: An Adaptive Platform Trial for Critically Ill Patients |
Coronavirus disease 19 infection, Respiratory distress syndrome |
ARDS supportive care alone, anticoagulation treatment alone, lung protective ventilation alone, Variable regimens including apremilast , cenicriviroc , icatibant , razuprotafib , remdesivir |
Bradykinin B2 receptor antagonist, CCR2 chemokine antagonist, CCR5 chemokine antagonist, COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, PDE 4 inhibitor, Protein tyrosine phosphatase beta inhibitor, RNA polymerase modulator, Tek tyrosine kinase receptor stimulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
QuantumLeap Healthcare Collaborative, US, University of California San Francisco |
Aerpio Pharmaceuticals Inc, Columbia University, Emory University, Montefiore Medical Center, Sanford Health, University of Alabama at Birmingham, University of California San Diego, University of Colorado, Denver, US, University of Minnesota, University of Pennsylvania, University of Southern California, Wake Forest University Health Sciences, US, Yale University |
US |
2020-07-31 |
2022-11-01 |
I-SPY COVID-19, I-SPY-COVID, NCT04488081 |
Phase 2 Clinical |
Recruiting |
10 |
27 Months |
1500 |
Amy Clark, MD, Angela Howell, MD, Carolyn Calfee, MD, Carolyn Carolyn, MD, D. Clark Files, MD, Derek Russell, MD, Ellen Burnham, MD, Jeremy Beitler, MD, Jonathan Koff, MD, Julie Lang, MD, Karl Thomas, MD, Karyn DiGiorgio, MS, Kathleen D Liu, MD, Kathleen Liu, MD, Kristy Watkins, RN, Laura Esserman, MD, Lauren Bayne, Leslie Segal, MPH, Michelle Gong, MD, Paul Berger, MD, Paul Henderson, PhD, Sheetal Gandotra, MD, Tessa Mcspadden, Trisha Burello, MS, Valerie Caterinicchia, RN, BSN |
2020-08-13 |
| LUS-COVID: Lung Ultrasound in COVID-19 Patients |
Coronavirus disease 19 infection |
invasive ventilation alone, lung ultrasound examination alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Academic Medical Center, University of Amsterdam |
Centre Hospitalier Universitaire Saint Pierre, Ospedale generale regionale F. Miulli, Acquaviva delle Fonti, Universita di Bari, Universita' Degli Studi Di Foggia |
Netherlands |
2020-06-01 |
2020-10-31 |
LUS-COVID, LUS-COVID, NCT04487769 |
Phase Not Applicable |
Recruiting |
1 |
5 Months |
30 |
Charalampos Pierrakos, MD, Lieuwe D Bos, MD PhD, Luigi Pisani, MD, Marcus J Schultz, MD, Marcus J Schultz, MD PhD |
2020-07-30 |
| COVID-19 Phobia in Patients With Bronchiectasis During Covid-19 Pandemic |
Anxiety disorder, Bronchiectasis, Coronavirus disease 19 infection, Phobia |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Hacettepe University |
|
Turkey |
2020-07-23 |
2020-12-01 |
GO 20/602, NCT04487873 |
Phase Not Applicable |
Not yet recruiting |
1 |
4 Months |
28 |
Aslıhan Cakmak, MSc, Deniz İnal-İnce, Professor, Ebru Calik-Kütükcü, PhD, Melda Saglam, PhD, Merve Firat, MSc, Naciye Vardar-Yagli, PhD |
2020-07-30 |
| COVIE-19/20: Screening for Postpartum Depression and Associated Risk Factors Among Women Who Deliver in Four Hospital in France During the COVID-19 Epidemic |
Coronavirus disease 19 infection, Postnatal depression |
Edinburgh Postnatal Depression Scale alone, Mother-to-Infant Bonding Scale alone, State-Trait Anxiety Inventory alone |
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire D Amiens |
Centre Hospitalier Compiègne, Centre hospitalier de Beauvais, Hospital Center De Saint-Quentin |
France |
2020-07-21 |
2021-08-31 |
COVIE-19/20, NCT04487171, PI2020_843_0049 |
Phase Not Applicable |
Recruiting |
1 |
13 Months |
248 |
Arthur FOULON, MD, Arthur Foulon, MD, MD, Xavier BENAROUS, MD |
2020-07-31 |
| ISAM-COVID: Survey on COVID-19 Airway Management |
Coronavirus disease 19 infection, Respiratory failure |
|
|
Healthy volunteers accepted |
Sociedad Española de Anestesiología, Reanimación y Terapéutica del Dolor |
|
Spain |
2020-04-22 |
2020-09-30 |
ISAM-COVID, ISAM-COVID, NCT04487977 |
Phase Not Applicable |
Recruiting |
1 |
5 Months |
5000 |
Dr. Manuel Granell Gil, Manuel Granell Gil, Manuel Granell Gil, Dr, Manuel Granell Gil, PhD |
2020-08-04 |
| Addressing COVID-19 Mental Health Problems Among US Veterans |
Acute stress disorder, Coronavirus disease 19 infection |
short video intervention alone, vignette intervention alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Research Foundation for Mental Hygiene Inc |
|
US |
2020-07-06 |
2020-09-10 |
8006, NCT04484207 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
200 |
Doron Amsalem, MD, Yuval Neria Neria, PhD, Yuval Neria, PhD |
2020-07-29 |
| Study of acute stroke with COVID-19 |
Coronavirus disease 19 infection, Stroke |
|
|
|
Japan Stroke Society, Nippon Medical School Hospital |
|
Japan |
2020-07-08 |
|
UMIN000041226 |
Phase Not Applicable |
Recruiting |
1 |
|
100 |
Kazumi Kimura, Yasuhiro Nishiyama |
2020-07-31 |
| Nebulized PL for Post-COVID-19 Syndrome |
Coronavirus disease 19 infection, Dyspnea, Respiratory disease, Respiratory distress syndrome, Viral pneumonia |
nebulized platelet lysate alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Regenexx LLC |
|
US |
2020-08-03 |
2021-12-30 |
NCT04487691, RGX2020-RCT01 |
Phase 1 Clinical |
Not yet recruiting |
1 |
16 Months |
40 |
Christopher Centeno, MD, Ehren Dodson, PhD, Neven Steinmetz, PhD |
2020-08-06 |
| A trial to evaluate sbk-001 for the treatment of SARS-CoV-2 infection (COVID-19) |
Coronavirus disease 19 infection |
sbk-001 alone |
Angiotensin converting enzyme 2 inhibitor |
|
Chengdu Shibeikang Biological Medicine Technology Co Ltd |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-07-28 |
| Oral Manifestations of Coronavirus Disease 2019(COVID-19) :a Multicenter Study |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs) |
Cairo University |
|
Egypt |
2020-09-15 |
2020-12-15 |
8791, NCT04487665 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
50 |
Dina mounir elkady |
2020-07-29 |
| Immune responses in the convalescence stage of COVID-19 patients |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Yokohama City University |
|
Japan |
2020-09-01 |
|
UMIN000041227 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
140 |
Atsushi Goto, Takeharu Yamanaka |
2020-07-30 |
| J-DESIRE: Japan COVID-19 Survey and Questionnaire in inflammatory bowel disease |
Anxiety disorder, Coronavirus disease 19 infection, Psychiatric disorder |
questionnaire survey alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Japanese Ancestry |
Sapporo Medical University School of Medicine |
Japanese Ministry of Health, Labor and Welfare |
Japan |
2020-07-28 |
|
J-DESIRE, UMIN000041191 |
Phase Not Applicable |
Not yet recruiting |
2 |
|
2500 |
Hiroshi Nakase, Kohei Wagatsuma |
2020-07-30 |
| CoV-Hep: Regional Anticoagulation Modalities in Continuous Venous Venous Hemodialysis in Patients With COVID-19 |
Coronavirus disease 19 infection, Renal injury |
continued venovenous hemodialysis alone, polysulfone dialyzer alone, sodium citrate plus unfractionated heparin |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo |
|
Brazil |
2020-06-29 |
2021-07-31 |
33351120.0.0000.0068, 4.081.688, CoV-Hep, NCT04487990, RBR-45kf9p, U1111-1252-0194 |
Phase 2 Clinical |
Recruiting |
1 |
13 Months |
90 |
Camila Rodrigues, MD, PhD, Paulo Lins, MD |
2020-07-30 |