Last updated: Sep 08, 2020 - 02:00 BST

Title Indication Intervention Actions PatientSelection Sponsor Collaborator Country StartDate EndDate Identifiers Phase Recruitment Status Sites Trial Duration Enrollment Count Contacts LastChanged
COVID-FIS: Pilot in COVID-19 (SARS-CoV-2) of Fisetin in Older Adults in Nursing Homes Coronavirus disease 19 infection, Inflammatory disease fisetin alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mayo Clinic, Minnesota National Institute on Aging US 2020-12-31 2023-12-31 1R01AG072301 - 01, 20-008867, COVID-FIS, NCT04537299 Phase 2 Clinical Not yet recruiting 0 36 Months 150 James L Kirkland, MD, PhD 2020-09-05
VIVID: Vitamin D and COVID-19 Trial Coronavirus disease 19 infection vitamin D3 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Brigham & Women's Hospital Fenway Community Health, Harvard Medical School, Harvard Pilgrim Health Care, Harvard TH Chan School of Public Health, Karolinska Institutet, Quest Diagnostics Inc, Takeda Pharmaceutical Co Ltd, Tishcon Corp US 2020-09-15 2021-01-15 2020J-009152, NCT04536298, VIVID Phase 3 Clinical Not yet recruiting 0 4 Months 2700 Davaasambuu Ganmaa, PhD, JoAnn E Manson, MD, DrPH, Rui Wang, PhD, Trisha Copeland, MS, RD 2020-09-06
A Study to Evaluate a Range of Dose Levels and Vaccination Intervals of Ad26.COV2-S in Healthy Adults Coronavirus disease 19 infection JNJ-78436735 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Janssen Vaccines & Prevention BV, Johnson & Johnson Germany, Netherlands, Spain 2020-08-28 2021-12-15 2020-002584-63, CR108854, NCT04535453, VAC31518COV2001 Phase 2a Clinical Recruiting 0 15 Months 550 Janssen Vaccines & Prevention B.V. Clinical Trial, Study Contact 2020-09-05
A Study of Brexanolone for Acute Respiratory Distress Syndrome Due to COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome brexanolone alone GABA A receptor modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) SAGE Therapeutics Inc 2020-11-30 2021-10-31 547-ARD-301, NCT04537806 Phase 3 Clinical Not yet recruiting 0 11 Months 100 Ariel Brown, PhD 2020-09-05
CINAMOPS: Critical Illness Polyneuropathy and Myopathy: Outcome, Predictors and Longitudinal Trajectories. A cohort study Coronavirus disease 19 infection, Myopathy, Polyneuropathy Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Schoen Clinic Bad Aibling Else Kröner-Fresenius Stiftung Germany 2020-09-15 20-166, CINAMOPS, DRKS00021753, U1111-1257-8461 Phase Not Applicable Not yet recruiting 0 250 Marion Egger 2020-09-06
NoCOVImpact: Impact of COVID-19 Outbreak on Non-COVID-19 Patients Coronavirus disease 19 infection Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopitaux Universitaires De Geneve Switzerland 2020-03-01 2020-10-31 2020-01017, NCT04537559, NoCOVImpact Phase Not Applicable Recruiting 0 8 Months 40000 Jerome Stirnemann, MD 2020-09-05
A Comparison of Sample Collection Methods for SARS-COV-2 Antibody Testing Coronavirus disease 19 infection finger-stick method alone, saliva collection alone, traditional phlebotomy alone Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Salveo Diagnostics US 2020-09-30 2022-09-30 NCT04537572, R2020-1002 Phase Not Applicable Not yet recruiting 0 24 Months 300 Stephen A Varvel, PhD 2020-09-05
BCG-PRIME: Prevention Of Respiratory Tract Infection And Covid-19 Through BCG Vaccination In Vulnerable Older Adults Coronavirus disease 19 infection, Respiratory tract infection BCG-Vaccine-Danish strain 1331 alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitair Medisch Centrum Utrecht Netherlands 2020-08-25 2021-04-30 BCG-PRIME, BCG-PRIME, NCT04537663 Phase 4 Clinical Recruiting 0 8 Months 5200 Ad Dees Dees, MD, PhD, Annelies Verbon, MD, PhD, Barbara Munster Munster, MD, PhD, Coen Stehouwer, MD, PhD, Corine de Haas, Eefje Jong, MD, PhD, Frits Rosendaal, MD, PhD, Hazra Moeniralam, MD, PhD, Heidi Ammerlaan, MD, PhD, Henk Kramer, MD, PhD, Jacobien Hoogerwerf, MD, PhD, Jan Kluijtmans, MD, PhD, Jan-Jelrik Oosterheert, MD, PhD, Kees Brinkman, MD, PhD, Kees van Nieuwkoop, MD, PhD, Kitty Slieker, MD, Marc Bonten, MD, PhD., Martin Grobusch, MD, PhD, Mihai Netea, MD, PhD, Rob Slingerland, MD, PhD, Robert-Jan Hassing, MD, PhD, Ton Dofferhoff, MD, PhD, Walther Sipers, MD, PhD 2020-09-05
Study of Recombinant Protein Vaccine Formulations Against COVID-19 in Healthy Adults >/= 18 Years of Age Coronavirus disease 19 infection SARS-CoV-2 vaccine (COVID-19), Sanofi Pasteur/GlaxoSmithKline alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sanofi SA GlaxoSmithKline plc US 2020-09-30 2021-10-31 NCT04537208, U1111-1250-4757, VAT00001 Phase 1/Phase 2 Clinical Recruiting 0 13 Months 440 Clinical Sciences & Operations 2020-09-05
MEND: The Mesenchymal CoviD-19 Trial: a Pilot Study to Investigate Early Efficacy of MSCs in Adults With COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome mesenchymoangioblast-derived mesenchymal stem cell therapy (Cymerus, critical limb ischemia/graft versus host disease/asthma/diabetic foot ulcer), Cynata/FUJIFILM alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cynata Therapeutics Ltd Cerebral Palsy Alliance Research Foundation Australia 2020-08-24 2021-03-31 CYP-COVID-19-01, MEND, NCT04537351 Phase 1/Phase 2 Clinical Recruiting 0 7 Months 24 Cynata Project Manager, Kilian Kelly, PhD 2020-09-05
Virtual Reality Therapy Influence on Heart Rate Variability of Inpatients With COVID-19 Coronavirus disease 19 infection MoveHero (University of Sao Paulo) alone, conventional exercise alone, virtual reality therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Sao Paulo Federal University of Sao Paulo Brazil 2020-06-18 2020-12-01 33244620.5.0000.5505, NCT04537858 Phase Not Applicable No longer recruiting 0 5 Months 50 Talita D da Silva, Ph.D., Talita Dias da Silva 2020-09-05
RESPIRA: Evaluation of the Immune Response to SARS-CoV-2 Among Patients With Covid-19 in Costa Rica Coronavirus disease 19 infection Healthy volunteers accepted, Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Deutsches Krebsforschungszentrum, Fundación Inciensa, Ministry of Health of Costa Rica, National Institutes of Health Costa Rica 2020-09-14 2022-09-14 NCT04537338, R020-SABI-00261, RESPIRA Phase Not Applicable Not yet recruiting 0 24 Months 2000 Rebeca Ocampo, Médica, Rolando Herrerro, Médico, Viviana Loría, Médica 2020-09-05
COVINVAC: Vaccination of Ex-acute COVID-19 Patients With Fibrosing Lung Syndrome at Discharge Coronavirus disease 19 infection, Interstitial lung disease, Pulmonary fibrosis, Respiratory disease, Viral pneumonia IN-01 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto Oncologico Rosell, Barcelona, Spain In3bio Ltd Spain 2020-12-01 2022-06-30 2020-002874-28, COVINVAC, NCT04537130, PANIN3BIO/IN01_COVID19_01 Phase 1b Clinical Not yet recruiting 0 19 Months 40 Federico Nepote, Investigator Selected by Sponsor, Pablo Rubinstein, MD, MSc, PhD, Verónica Roca 2020-09-05
The Co-CLARITY Trial: A Randomized, Non-Placebo Controlled, Open-Label, Single-Center Clinical Trial to Assess the Efficacy and Safety of Convalescent Plasma Given in Two Consecutive Aliquots to Hospitalized Adult COVID-19 Patients as Adjunctive Therapy to Reduce the Need for ICU Admission Coronavirus disease 19 infection convalescent plasma therapy alone University of the Philippines Manila Philippine Council for Health Research and Development Philippines 2020-07-01 2021-07-01 2020-CT0554, PHRR200824-002868, The Co-CLARITY Trial, UPMREB 2020-300-01 Phase 3 Clinical Not yet recruiting 0 12 Months 136 Deonne Thaddeus Gauiran 2020-09-05
Compare marker abnormalities in COVID positive and negative cancer patients Coronavirus disease 19 infection general anesthesia alone, surgery alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute Of Medical Sciences, Rishikesh India 2020-09-13 CTRI/2020/09/027518 Phase Not Applicable Not yet recruiting 0 40 Bhavna Gupta 2020-09-05
Knowledge, Attitudes and Clinical Practices of Pediatric Dentists Regarding Covid-19 Coronavirus disease 19 infection Fayoum University, EG Egypt 2020-04-20 2020-05-05 NCT04537117, PEDODONTISTS DURING COVID-19 Phase Not Applicable Completed 0 202 Maha M Azab, PhD 2020-09-04
Swallowing Impairment After COVID-19 Infection Coronavirus disease 19 infection, Dysphagia Oropharyngeal swallowing examination alone, Videofluoroscopy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The University Health Network McMaster University, National Institute on Deafness and Other Communication Disorders, University of Florida Canada, US 2020-09-01 2021-12-31 3R01DC011020-08S1, CAPCR 20-5477, NCT04537650 Phase Not Applicable Not yet recruiting 0 16 Months 75 Ashwini M Namasivayam-MacDonald, PhD, Catriona M Steele, PhD, Emily K Plowman, PhD, Renata Mancopes, PhD 2020-09-04
A Trial Investigating the Safety and Effects of One BNT-162 Vaccine Against COVID-19 in Healthy Adults Coronavirus disease 19 infection BNT-162b3 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) BioNTech RNA Pharmaceuticals GmbH BioNTech SE Germany 2020-09-30 2021-12-31 2020-003267-26, BNT162-04, NCT04537949, U1111-1254-4840 Phase 1/Phase 2 Clinical Not yet recruiting 0 15 Months 120 BioNTech Responsible Person, BioNTech clinical trial information desk, BioNTech clinical trials patient information 2020-09-04
C2Rx Hemofiltration Treatment in Severe or Critically Ill Adults With COVID-19 Coronavirus disease 19 infection, Respiratory failure CLR2.0 device alone, hemofiltration alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Seastar Medical Inc 2020-09-15 2021-01-15 CP-01-004, NCT04537975 Phase Not Applicable Not yet recruiting 0 4 Months 30 Eric Schlorff 2020-09-04
Covid 19 and Professional course students quality of life Coronavirus disease 19 infection web based survey alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Haldia Institute of Dental Sciences & Research India 2020-09-10 CTRI/2020/09/027544 Phase Not Applicable Not yet recruiting 0 636 Arnab Ganguly, Swet Nisha 2020-09-04
Management of cardiac disease during COVID-19 pandemic and impact among cardiologist in Tamil Nadu Acute coronary syndrome, Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) India 2020-09-07 C3RF002, CTRI/2020/09/027517 Phase Not Applicable Not yet recruiting 0 100 Dr B Vinod Kumar, Dr S Nagendra Boopathy, Dr T R Muralidharan 2020-09-04
Coronavirus infection among healthcare workers Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) B.Y.L Nair Charitable Hospital India 2020-09-07 CTRI/2020/09/027516 Phase Not Applicable Not yet recruiting 0 500 Dr Niraj Mahajan 2020-09-04
Effects of health drink additional to standard of care treatment in COVID 19 patients Coronavirus disease 19 infection Mulmina Mango alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Jagdale industries pvt Ltd India 2020-09-12 CTRI/2020/09/027548 Phase Not Applicable Not yet recruiting 0 50 Dr MS Madhu, Raghavendra KV, Subham Dutta 2020-09-04
Efficacy and safety study of antiviral Umifenovir therapy in non-severe COVID- 19 patients Coronavirus disease 19 infection Umifenovir alone, standard care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Central Drug Research Institute India 2020-09-08 CDRI-CLINICAL2/2020, CTRI/2020/09/027535, U1111-1251-8421 Phase 3 Clinical Not yet recruiting 0 132 Dr M MA Faridi, Dr Virendra Atam, Dr Vivek Bhosale MD, v 2020-09-04
A phase II trial to evaluate galidesivir in non-hospitalized COVID-19 patients at high risk for developing severe disease and complications of COVID-19 Coronavirus disease 19 infection galidesivir alone RNA polymerase inhibitor BioCryst Pharmaceuticals Inc Phase 2 Clinical Planned 0 2020-09-04
Effects of Nitazoxanide Administration to Patients in the Initial Phase of COVID-19 Coronavirus disease 19 infection nitazoxanide alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Associacao Paulista para o Desenvolvimento da Medicina, Hospital e Maternidade Therezinha de Jesus, Secretaria de Saúde do Distrito Federal, Universidade Federal do Rio de Janeiro Conselho Nacional de Desenvolvimento Cientifico e Tecnologico - CNPq, Ministério da ciência, tecnologia e inovação fundação de amparo a pesquisa do estado de São Paulo Brazil 2020-06-08 32258920.0.1001.5257, 4.043.191, RBR-4nr86m Phase 3 Clinical Recruiting 0 392 Fernanda Ferreira Cruz, Patricia Rieken Macedo Rocco, Pedro Leme Silva 2020-09-04
PGE1-COVID19: Cri Analog PG1 Effectiveness and Safety in Covid-19 Coronavirus disease 19 infection, Hypoxia, Respiratory disease, Viral pneumonia empirical antibiotic therapy alone, Variable regimens including alprostadil , dexamethasone , enoxaparin sodium , low molecular weight heparin , tocilizumab Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundacion Santa Fe De Bogota Colombia 2020-10-01 2021-03-01 CEIS-2020-089, NCT04536363, PGE1-COVID19 Phase 2 Clinical Not yet recruiting 0 5 Months 284 Alonso Vera Torres, Alonso Vera Torres, MD, Jose De la Hoz, MD 2020-09-04
LIVE: Live@Home.Path: Innovating the Clinical Pathway for Home Dwelling Persons With Dementia and Their Families Coronavirus disease 19 infection, Dementia LIVE alone, multicomponent intervention alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Bergen Haraldsplass Deaconess Hospital, King's College London, McLean Hospital Corp, National Association for Public Health, Norwegian National Advisory Unit on Rare Disorders, Norwegian Research Centre, The University of Hong Kong, Tohoku University, Universiteit Leiden, University College London, Western Norway University of Applied Sciences, Yale School of Medicine Norway 2019-08-01 2021-06-30 LIVE, NCT04043364, NFR 273581 Phase Not Applicable Recruiting 0 23 Months 312 Bettina Husebø, MD, PhD, Bettina Husebø, MD,PhD, Line I Berge, MD,PhD 2020-09-04
COVID-19 Related Public Health Literacy Coronavirus disease 19 infection Health infographics through facebook application alone Malaysia 2020-11-02 2021-05-17 56068, NMRR-20-1867-56068 Phase Not Applicable Status not specified 0 6 Months PUAN NOR AYUNI BINTI AB RAHMAN 2020-09-04
Effect of prone positioning with HFNC on oxygenation and overall outcomes in severe COVID-19 patients Coronavirus disease 19 infection, Respiratory failure High Flow Nasal Cannula alone, Prone Positioning alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Maulana Azad Medical College India 2020-10-01 CTRI/2020/09/027562, F.1/IEC/MAMC/79/07/2020/200 Phase Not Applicable Not yet recruiting 0 92 Dr Amit Kohli, Dr Deepak Kumar 2020-09-04
Detection of specific antibodies (IgM and IgG) in sera from patients with COVID-19 and patients under investigation for COVID-19 in Malaysia Coronavirus disease 19 infection National Institutes of Health Malaysia Malaysia 2020-09-07 2021-05-31 55677, NMRR-20-1866-55677 Phase Not Applicable Status not specified 0 8 Months Dr ROZAINANEE MOHD ZAIN 2020-09-04
Identifying homeopathy medicines in use for protection against COVID-19, calculating the number of COVID-19 cases or cases with COVID-19 like symptoms in these homeopathy users and identifying some general features like age, gender and location in them Coronavirus disease 19 infection homeopathy medicines alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Switzerland, China, United Arab Emirates, Norway, Germany, UK, Italy, Australia, US, Thailand, Belgium, Singapore, Sweden, Hong Kong, India, Canada 2020-09-15 CTRI/2020/09/027560, U1111-1255-9014 Phase Not Applicable Not yet recruiting 0 6500 Kushal Banerjee 2020-09-04
CPCP: Clinical Pharmacist in a COVID Hospital - A Malaysian Experience Coronavirus disease 19 infection Hospital Sungai Buloh Malaysia 2020-08-29 2020-12-31 55720, CPCP, NMRR-20-1854-55720 Phase Not Applicable Status not specified 0 4 Months Miss PEE LAY TING 2020-09-04
First Responder Resiliency Program During COVID-19 Coronavirus disease 19 infection Resilience Program alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mayo Clinic Foundation US 2020-09-15 2021-12-31 20-005017, NCT04536376 Phase Not Applicable Not yet recruiting 0 15 Months 10 Brent Bauer, MD, Ivana T Croghan, PhD, Shawn C Fokken, BS, Stephanie A Lindeen, RN 2020-09-04
Assessing People's Hospital Outpatient Appointment Preferences in the United Kingdom Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Warwick University UK 2020-09-01 2020-09-30 BSREC 110/19-20, NCT04536259 Phase Not Applicable Not yet recruiting 0 1 Month 1000 Kelly A Schmidtke, PhD 2020-09-04
Hospitalized Children and Adolescent Patients With Type 1 Diabetes During the COVID-19 Pandemic in Egypt Coronavirus disease 19 infection, Insulin dependent diabetes Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Ain Shams University Egypt 2020-05-01 2020-08-31 FMASU P59/2020, NCT04536285 Phase Not Applicable Completed 0 4 Months 36 Eman Monir Sherif, Yasmine Elhenawy 2020-09-04
Biosurveillance and KAP COVID-19 cats Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Malaysia 2020-10-01 2021-01-31 55758, NMRR-20-1834-55758 Phase Not Applicable Not yet recruiting 0 4 Months Dr Farina Binti Mustaffa Kamal, Dr Nur Indah Binti Ahmad 2020-09-04
COMPASS: An Online Cognitive-behavioural Therapy (CBT) Program Treating Anxiety and Low Mood in Long-term Conditions During the COVID-19 Pandemic Anxiety disorder, Coronavirus disease 19 infection COMPASS alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) King's College London Diabetes UK, Multiple Sclerosis (MS) Society, UK UK 2020-09-28 2021-06-01 20347, COMPASS, NCT04535778 Phase Not Applicable Not yet recruiting 0 8 Months 200 Katrin Hulme, Natasha Seaton, Natasha Seaton, Msc, Rona Moss-Morris 2020-09-04
Mobile Mental Health Apps for Suicide Prevention Anxiety disorder, Coronavirus disease 19 infection, Depression Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Washington 2020-09-30 2020-12-31 NCT04536935, STUDY00010842 Phase Not Applicable Not yet recruiting 0 3 Months 2000 Brittany Mosser, MSW, Kate Comtois, PhD 2020-09-04
Ultra-brief Online Mindfulness-based Intervention During COVID-19 Movement Control Order Coronavirus disease 19 infection Ultra Brief Online Mindfulness-based Intervention alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universiti Tunku Abdul Rahman Sunway University Malaysia 2020-04-01 2020-06-30 NCT04536441, U/SERC/62/2020 Phase Not Applicable Completed 0 3 Months 161 Kai-Shuen Pheh, MClinPsych 2020-09-04
Dental Students Health and Well being During Covid-19 Pandemic Coronavirus disease 19 infection Healthy volunteers accepted, Female, Young Adults (18-44 yrs) Haldia Institute of Dental Sciences & Research India 2020-09-10 CTRI/2020/09/027558 Phase Not Applicable Not yet recruiting 0 480 Arnab Ganguly, Swet Nisha 2020-09-04
Efficacy of Vitamin D Supplementation to Prevent the Risk of Acquiring COVID-19 in Healthcare Workers (COVID-19) Coronavirus disease 19 infection vitamin D alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Coordinacion de Investigacion en Salud Hospital Infantil de Mexico Federico Gomez Mexico 2020-07-15 2021-07-31 NCT04535791, R-2020-785-090 Phase 3 Clinical Recruiting 0 12 Months 400 Carla Castuera Martinez, Clara Santacruz-Tinoco, PhD, Concepcion Grajales-Muñiz, PhD, Guadalupe Miranda-Novales, PhD, Jessie Zurita-Cruz, MD, Jessie Zurita-Cruz, PhD, Mardia Lopez-Alarcon, PhD, Miguel Angel Villasis-Keever, Miguel Angel Villasis-Keever, MD, Miguel Angel Villasis-Keever, PhD 2020-09-04
Effect of comorbidities in the outcome of COVID-19 patients, a study in tertiary care centre ICU in India Coronavirus disease 19 infection, Respiratory tract infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Vardhman Mahavir Medical College & Safdarjung Hospital India 2020-09-14 CTRI/2020/09/027572 Phase Not Applicable Not yet recruiting 0 350 Deepa Kerketta Khurana 2020-09-04
Inhaled Aviptadil for the Prevention of COVID-19 Related ARDS Coronavirus disease 19 infection, Respiratory distress syndrome aviptadil alone, standard care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kantonsspital Baselland Switzerland 2020-09-30 2021-12-31 AVIPTADIL TRIAL, NCT04536350 Phase 1 Clinical Not yet recruiting 0 15 Months 80 Jörg D Leuppi, Professor, Kristin Abig, Michael Brändle, Professor, Prof. Dr. Jorg Leuppi 2020-09-04
A case-study of critically ill COVID-19 patient who showed successful response to plasma exchange followed by intravenous immunoglobulin Coronavirus disease 19 infection, Respiratory failure intravenous immunoglobulin alone, plasma exchange alone Female People's Hospital of Guizhou Province Phase Not Applicable Status not specified 0 1 2020-09-04
An observational, case report to determine the safety and efficacy of triple combination therapy with lopinavir/ritonavir, hydroxychloroquine, and interferon beta-1b in COVID-19 pneumonia patients Coronavirus disease 19 infection, Pneumonia Variable regimens including hydroxychloroquine , interferon beta-1b , lopinavir + ritonavir , methylprednisolone HIV protease inhibitor National Research Foundation of Korea Phase Not Applicable Status not specified 0 5 2020-09-04
An observational, cohort study to evaluate the impact of addition of corticosteroids to the hospital protocol in treatment of patients with suspected or confirmed COVID-19 pneumonia Coronavirus disease 19 infection, Pneumonia corticosteroids alone Centre Hospitalier Universitaire de Reims Phase Not Applicable Status not specified 0 257 2020-09-04
C-SMART (Arm 1): C-SMART. COVID-19 Prevention and Treatment in Cancer. Arm 1 : Prevention in Patients Not Infected with COVID-19 Coronavirus disease 19 infection Variable regimens including interferon-alpha , lenzilumab , selinexor Exportin 1 inhibitor, GM-CSF ligand inhibitor, Immunoglobulin G1 modulator, Immunoglobulin kappa modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Peter MacCallum Cancer Centre Australian Government Australia 2020-09-01 2021-12-01 ACTRN12620000843954, ANZCTR380380, C-SMART (Arm 1), HREC/65954/PMCC, U1111-1256-8488 Phase 3 Clinical Not yet recruiting 0 15 Months 1914 Michelle Yong, Monica Slavin, Ronan Burder 2020-09-04
Increasing immunization in general practice against invasive pneumococcal disease and influenza in people < 65 years old whose chronic conditions put them at higher risk of and from these infections Coronavirus disease 19 infection, Influenza virus infection, Streptococcus pneumoniae infection Doctor's control panel software (DCP) alone, SMS immunization reminder alone, reminder letter alone, telehealth consultation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) University of Adelaide Australia 2020-06-08 ACTRN12620000614998, ANZCTR379321, H-2020-044 Phase Not Applicable Not yet recruiting 0 6000 Oliver Frank 2020-09-04
C-SMART (Arm 2): COVID-19 prevention and treatment in cancer. Arm 2: post-exposure prevention in patients recently exposed to COVID-19 Coronavirus disease 19 infection, Respiratory tract infection interferon-alpha alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Australian Government, Peter MacCallum Cancer Centre Australia 2020-09-01 2021-12-01 ACTRN12620000842965, ANZCTR380422, C-SMART (Arm 2), HREC/65954/PMCC, U1111-1256-8488 Phase 3 Clinical Not yet recruiting 0 15 Months 170 Michelle Yong, Monica Slavin, Ronan Burder 2020-09-05
A trial to evaluate VIR-7831 for the prophylaxis of symptomatic COVID-19 infection Coronavirus disease 19 infection VIR-7831 alone COVID19 Spike glycoprotein modulator Vir Biotechnology Inc Phase Not Applicable Planned 0 2020-09-03
A trial to evaluate VIR-7831 for the treatment of severely ill hospitalized COVID-19 patients Coronavirus disease 19 infection VIR-7831 alone COVID19 Spike glycoprotein modulator Vir Biotechnology Inc Phase Not Applicable Planned 0 2020-09-03
Therapeutic Study to Evaluate the Safety and Efficacy of DW-MSC in COVID-19 Patients Coronavirus disease 19 infection allogeneic mesenchymal stem cells (DW-MSC) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) INA-RESPOND Secretariat Daewoong Pharmaceutical Co Ltd, National Institute Of Health Research & Development (Nihrd)- Ministry Of Health Of The Republic Of Indonesia Indonesia 2020-09-11 2020-12-31 DW_DWP710101, NCT04535856 Phase 1 Clinical Not yet recruiting 0 3 Months 9 Dr. Muhammad Karyana, MPH, dr. Dona Arlinda, M.Sc. 2020-09-05
Treatment for Severe Pneumonia in Patients with Coronavirus Coronavirus disease 19 infection, Viral pneumonia EF-168 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ministério da ciência, tecnologia e inovação fundação de amparo a pesquisa do estado de São Paulo Financiadora de Estudos e Projetos Brazil 2020-04-30 3.979.532, 30662420.0.1001.0008, B878.596.297-04, RBR-88bs9x Phase 3 Clinical Recruiting 0 500 Fernanda Ferreira Cruz, Patricia Rieken Macedo Rocco, Pedro Leme Silva 2020-09-04
Umbilical cord-derived mesenchymal stromal cells therapy for SARS-CoV-2 infection (COVID-19) related Acute Respiratory Distress Syndrome Coronavirus disease 19 infection, Respiratory distress syndrome HLC-001 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Human Life CORD Japan Inc Japan 2020-10-01 2021-09-30 JapicCTI-205465 Phase 1 Clinical Not yet recruiting 0 12 Months 12 2020-09-05
To study ease of using intubation(aerosol) box in patients undergoing general anesthesia for elective surgeries during the coronavirus disease pandemic Coronavirus disease 19 infection, General anesthesia Endotracheal intubation alone, modified aerosol box alone, Variable regimens including fentanyl , glycopyrrolate , midazolam hydrochloride , oxygen , propofol, AstraZeneca/Fresenius , succinyl-choline Benzodiazepine receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Jawaharlal Nehru Medical College KLES Prabhakar Kore Hospital and Medical Research Center India 2020-09-01 CTRI/2020/08/027489, U1111-1256-5515 Phase 2 Clinical Not yet recruiting 0 110 DrNeha Sanjeev Adhyapak, DrRajesh S Mane 2020-09-03
The Incidence of Critical Illness Related Corticosteroid Insufficiency and Clinical Outcomes of Critically Ill Patients with COVID-19 at the Philippine General Hospital Coronavirus disease 19 infection Philippine General Hospital Philippines 2020-06-01 PHRR200827-002884 Phase Not Applicable Not yet recruiting 0 Anna Elvira Arcellana 2020-09-03
The impact of work loss during the COVID-19 pandemic on health and employment Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Monash University Australia 2020-03-27 2020-12-31 #24003, ACTRN12620000857909, ANZCTR380413 Phase Not Applicable No longer recruiting 0 9 Months 1829 Alex Collie 2020-09-03
Selfhelp in Covid -19 Pandemic: Health-related self-help strategies during the COVID-19 pandemic - an online-based cross-sectional study Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Charite Universitaetsmedizin Berlin Germany 2020-09-15 DRKS00022909, EA2/127/20, Selfhelp in Covid -19 Pandemic Phase Not Applicable Not yet recruiting 0 2000 Margit Cree, Miriam Ortiz 2020-09-04
Seroprevalence of COVID-19 in Thailand Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Thailand 2020-09-15 TCTR20200828001 Phase Not Applicable Not yet recruiting 0 400 Nattachai Srisawat 2020-09-03
Seroprevalence of SARS-CoV-2 in communities in the Philippines Coronavirus disease 19 infection Research Institute for Tropical Medicine Philippine Council for Health Research and Development, Research Institute for Tropical Medicine Philippines 2020-07-27 PHRR200825-002878 Phase Not Applicable Not yet recruiting 0 4000 Catalino S. Demetria, DVM, Criselda T. Bautista, DVM, MVetEpi, Johanna Beulah T. Sornillo, Kristine Alvarado-Dela Cruz, MD, FPPS, DPIDSP, Marianette T. Inobaya, MSPH,PhD, Mayan U. Lumandas, MD, FPPS, DPIDSP, MSc, Timothy John R. Dizon, MD, MBA 2020-09-02
CORONA-VTE NET: COVID-19 Registry to Assess Frequency, Risk Factors, Management, and Outcomes of Arterial and Venous Thromboembolic Complications Bleeding, Coronavirus disease 19 infection, Deep vein thrombosis, Ischemia, Lung embolism, Myocardial infarction, Stroke, Thromboembolism Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Brigham & Women's Hospital Anne Arundel Medical Center, Beth Israel Deaconess Medical Center, Bristol-Myers Squibb Co, Jefferson Medical College, University of Colorado, Denver, US US 2020-03-24 2021-03-30 2020P000848, CORONA-VTE NET, NCT04535128 Phase Not Applicable Recruiting 0 12 Months 10000 Gregory Piazza, MD, MS 2020-09-03
How Brazilian Chiropractors Are Facing the COVID-19 Pandemic Coronavirus disease 19 infection Healthy volunteers accepted Brazil 2020-08-26 2020-09-18 NCT04534621, Treat Phase Not Applicable Not yet recruiting 0 948 MARCELO B BOTELHO, DC, MD, MSc 2020-09-04
Efficacy of Family Programs for Improving Child and Family Health and Development Coronavirus disease 19 infection Couples intervention alone, Home visits alone, Sensitivity intervention alone, Zoom app alone Healthy volunteers accepted, Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The University of Notre Dame du Lac Eunice Kennedy Shriver National Institute of Child Health & Human Development US 2017-01-11 2023-12-31 NCT03367845, NotreDame, R01HD087319 Phase Not Applicable Recruiting 0 83 Months 1200 Cheryl Lee, MA, E M Cummings, Ph.D., Julia Braungart-Rieker, Ph.D, Kathleen Bergman, PhD, Terri Sweeney, BA 2020-09-02
Consequences of the COVID-19 Lockdown on Health and Well-being of Patients With Parkinson Disease and Post-stroke Coronavirus disease 19 infection, Parkinsons disease, Stroke Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Haifa Israel 2020-05-10 2020-06-30 203/20, NCT04535297 Phase Not Applicable Completed 0 1 Month 198 Galit Yogev-Seligmann 2020-09-04
Mother-infant Bonding During COVID-19 Coronavirus disease 19 infection Family Nurture Intervention (FNI) alone Healthy volunteers accepted, Newborn Infants (up to 5 months) Columbia University US 2020-08-13 2021-12-31 AAAT0140, NCT04531618 Phase Not Applicable Recruiting 0 16 Months 280 Dani Dumitriu, Dani Dumitriu, MD, PhD, Martha Welch, MD 2020-09-04
Convalescent Plasma as Potential Therapy for Severe COVID-19 Pneumonia Coronavirus disease 19 infection, Multiple organ failure, Respiratory failure, Septic shock, Viral pneumonia Architect Plus, Abbott alone, COVID19 convalescent plasma alone, Chemiluminescent microparticle immunoassay alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centro de Educación Medica e Investigaciones Clínicas Norberto Quirno Argentina 2020-04-18 2021-02-25 NCT04535063, RValentini Phase 3 Clinical Recruiting 0 10 Months 200 Jorge Solimano, MD, José Fernández Grande, MD, Juan Dupont, MD, Ricardo Valentini, MD 2020-09-04
PROLUN: Patient-reported Outcomes and Lung Function After Hospitalization for COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Akershus Haukeland University Hospital, Oslo University Hospital, Ostfold Hospital Trust, St Olavs Hospital Norway 2020-03-31 2022-06-01 NCT04535154, PROLUN, PROLUN Phase Not Applicable No longer recruiting 0 26 Months 264 Gunnar Einvik, PhD 2020-09-03
Pegylated Interferon Lambda for Treatment of COVID-19 Infection Coronavirus disease 19 infection, Respiratory tract infection Standard of care alone, pegylated interferon lambda alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Soroka University Medical Center Israel 2020-08-05 2021-12-31 0129-20-SOR, NCT04534673, SCRC200006 Phase 2 Clinical Recruiting 0 16 Months 40 Ohad Etzion, MD, Ruthie Bekore 2020-09-03
QUANTICO-RETRO: Automated Quantification of Radiological Pulmonary Alteration During Acute Respiratory Failure Coronavirus disease 19 infection, Hypoxia, Respiratory failure thoracic CT-scan alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopitaux Universitaires de Strasbourg Visible Patient France 2020-09-01 2021-01-15 7888, NCT04534400, QUANTICO-RETRO Phase Not Applicable Recruiting 0 4 Months 1000 Bernard GOICHOIT, MD, Eric NOLL, MD, Francis SCHNEIDER, MD, Francis VEILLON, MD, Julien POTTECHER, MD, Mickaël OHANA, MD, Philippe FEUERSTEIN, MD, Pierre DIEMUNSCH, MD 2020-09-05
C-SMART: COVID-19 Prevention and Treatment in Cancer: a Sequential-Multiple-Assignment, Randomized Trial Coronavirus disease 19 infection, Respiratory tract infection, Viral pneumonia interferon-alpha alone, lenzilumab alone, selinexor alone Exportin 1 inhibitor, GM-CSF ligand inhibitor, Immunoglobulin G1 modulator, Immunoglobulin kappa modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Peter MacCallum Cancer Centre Australia 2020-09-30 2021-12-31 C-SMART, NCT04534725, Peter Mac ID 20/135 Phase 3 Clinical Not yet recruiting 0 15 Months 2282 Megan Crane, Ronan Burder, BsC Hons 2020-09-03
Lymphocyte - Monocyte Ratio As An Independent Predictor For Progression Of Illness In Patients With Covid-19 Coronavirus disease 19 infection, Viral pneumonia lymphocyte monocyte ratio prediction test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Postgraduate Institute of Medical Education and Research Sir Ganga Ram Hospital India 2020-09-01 2021-02-01 NCT04534712 Phase Not Applicable Not yet recruiting 0 5 Months 100 vamsidhar amburu, MD 2020-09-04
C19CHILD: COVID-19 Child Health Investigation of Latent Disease in Hamburg Coronavirus disease 19 infection Immunological analysis alone, Obligatory polymerase chain reaction alone, Serum antibody testing alone Healthy volunteers accepted, Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Universitätsklinikum Hamburg-Eppendorf Altona children's hospital, Asklepios Kliniken Hamburg GmbH Germany 2020-05-11 2021-03-31 C19CHILD, NCT04534608, PV7336 Phase Not Applicable No longer recruiting 0 10 Months 6000 Ania C Muntau, Professor, Soeren W Gersting, Professor, Thomas Mir, Professor 2020-09-03
Effect of curcumin in treatment of respiratory syndrome of corona Coronavirus disease 19 infection curcumin (Dineh Company) alone, usual medications alone Kermanshah University of Medical Sciences Iran 2020-08-31 IR.KUMS.REC.1398.1223, IRCT20200418047119N1 Phase 2/Phase 3 Clinical Recruiting 0 42 Mohammad Hossein Zamanian, Sajad Moradi 2020-09-04
First-In-Human Study To Evaluate Safety, Tolerability And Pharmacokinetics Following Single Ascending Dose And Extended Infusion of PF-07304814 In Hospitalized Participants With COVID-19 Coronavirus disease 19 infection PF-07304814 alone COVID19 replicase polyprotein 1a inhibitor, COVID19 replicase polyprotein 1ab inhibitor, Viral protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Pfizer Inc 2020-08-30 2021-02-27 2020-003905-73, C4611001, NCT04535167 Phase 1b Clinical Not yet recruiting 0 5 Months 56 Pfizer CT.gov Call Center 2020-09-04
RECHARGE: A Brief Psychological Intervention to Build Resilience in Healthcare Workers During COVID-19 Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder RECHARGE alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Zurich University of New South Wales Switzerland 2020-08-28 2021-06-01 BASEC-Nr.2020-00796, NCT04531774, RECHARGE Phase Not Applicable Not yet recruiting 0 9 Months 160 Naser Morina, PhD, Sonja Weilenmann, PhD 2020-09-05
BAC to the PAST: BCG Against Covid-19 for Prevention and Amelioration of Severity Trial Coronavirus disease 19 infection BCG Tokyo-172 alone Healthy volunteers accepted, Aged Adults (65-79 yrs), Elderly Adults (80 and over) Harvard Medical School Texas Medical Research Associates LLC US 2020-09-01 2021-11-30 BAC to the PAST, IRB20-1243, NCT04534803 Phase 3 Clinical Not yet recruiting 0 15 Months 2100 Megan B Murray, MD, ScD, Meredith Brooks, PhD, Ximena C Tovar 2020-09-04
SBHC: Data Collection on the Model Schools Pediatric Health Initiative at five SBHC Sites: COVID-19 Questionnaire Coronavirus disease 19 infection Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) St Michaels Hospital Canada 2019-04-30 2021-03-31 19-060, NCT04534595, SBHC Phase Not Applicable Recruiting 0 23 Months 1500 Sloane Freeman, MSc,MD,FRCPC 2020-09-04
Anti-inflammatory Effect of Low-Dose Whole-Lung Radiation for COVID-19 Pneumonia Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia radiotherapy (1 Gy) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto Mexicano del Seguro Social Mexico 2020-07-24 2021-04-05 NCT04534790, PI-2020-2858 Phase Not Applicable Recruiting 0 8 Months 30 Alejandro Olmos Guzman 2020-09-04
C-ARF: Expert Panel Statement for the Respiratory Management of COVID-19 Related Acute Respiratory Failure Coronavirus disease 19 infection, Respiratory failure Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) NMC Specialty Hospital United Arab Emirates 2020-09-06 2020-09-30 C-ARF, C19ARFstudy, NCT04534569 Phase Not Applicable Recruiting 0 35 Prashant Nasa 2020-09-04
NORCOVID: Oral Prednisone Regimens to Optimize the Therapeutic Strategy in Patients With Organizing Pneumonia Post-COVID-19 Coronavirus disease 19 infection, Viral pneumonia prednisone alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Vall D'Hebron 2020-09-07 2021-12-15 2020-003651-15, NCT04534478, NORCOVID Phase 4 Clinical Not yet recruiting 0 15 Months 120 Maria-Jesus Cruz, PhD 2020-09-03
Reshaping the Path of Vascular Cognitive Impairment (VCI) Amnesia, Babinski syndrome, Cerebrovascular disease, Cognitive disorder, Coronavirus disease 19 infection, Dysarthria, Ischemia, Movement disorder resistance exercise training alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of British Columbia Canada 2016-01-31 2021-12-31 H15-00972, NCT02669394 Phase Not Applicable Recruiting 0 71 Months 88 Charlie Goldsmith, PhD, Ging-Yuek Robin Hsiung, MD, PhD, Jennifer Davis, PhD, John Best, PhD, Kenneth Madden, MD, Roger Tam, PhD, Teresa Liu-Ambrose, PhD, PT, Thalia Field, MD, V5Z 1M9 2020-09-05
An investigator-led, multicenter, randomized study to evaluate nomacopan for the treatment of patients with COVID-19 pneumonia Coronavirus disease 19 infection, Viral pneumonia nomacopan alone Complement C5 factor inhibitor, Leukotriene BLT receptor antagonist Akari Therapeutics Plc US Phase Not Applicable Planned 0 60 2020-09-02
NRO-COV-50: Neurological rehabilitation outcome of the treatment of patients with COVID-19 disease Brain disease, Coronavirus disease 19 infection, Guillain Barre syndrome, Myopathy, Polyneuropathy, Stroke Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ludwig-Maximilians University of Munich Germany 2020-06-19 20-487, DRKS00022845, NRO-COV-50 Phase Not Applicable Recruiting 0 500 Andreas Bender, Gergana Drunin 2020-09-04
An expanded access, proof of principle program to evaluate nomacopan for the treatment of patients with COVID-19 pneumonia Coronavirus disease 19 infection, Viral pneumonia nomacopan alone Complement C5 factor inhibitor, Leukotriene BLT receptor antagonist Akari Therapeutics Plc US Phase Not Applicable Recruiting 0 2020-09-02
A trial to evaluate nomacopan for the treatment of patients with COVID-19 Coronavirus disease 19 infection nomacopan alone Complement C5 factor inhibitor, Leukotriene BLT receptor antagonist Akari Therapeutics Plc Africa 2020-12-31 Phase Not Applicable Planned 0 2020-09-02
A randomized study to evaluate nomacopan for the treatment of patients with COVID-19 pneumonia Coronavirus disease 19 infection, Viral pneumonia nomacopan alone Complement C5 factor inhibitor, Leukotriene BLT receptor antagonist Akari Therapeutics Plc Brazil 2020-12-31 Phase Not Applicable Planned 0 60 2020-09-02
A proof of principle clinical study to evaluate nomacopan in patients with COVID-19 pneumonia Coronavirus disease 19 infection, Viral pneumonia nomacopan alone Complement C5 factor inhibitor, Leukotriene BLT receptor antagonist Akari Therapeutics Plc Brazil Phase Not Applicable No longer recruiting 0 2020-09-02
Evaluation of slow release mucoadhesive paste of 'MUCODENTOL' in oral vestibule on symptoms of COVID-19 disease in hospital staff Coronavirus disease 19 infection Mucodentol alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Lorestan University Iran 2020-04-02 2020-09-05 IR.LUMS.REC.1399.013, IRCT20090304001739N3 Phase 2 Clinical Recruiting 0 5 Months 1600 Ebrahim Fallahi, Sepideh Vahabi, Sepideh vahabi 2020-09-04
Effects of two products containing Noscapine on COVID-19 Coronavirus disease 19 infection Noscough alone, opioucough alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mashhad University of Medical Sciences Iran 2020-09-22 IR.MUMS.REC.1399.283, IRCT20180103038199N3 Phase 2 Clinical Not yet recruiting 0 120 Vahid Reza Askari 2020-09-04
An observational, retrospective Italian survey study to determine the usefulness of hydroxychloroquine in the prevention of COVID-19 in patients under treatment for dermatological and rheumatological diseases Coronavirus disease 19 infection hydroxychloroquine alone Universita degli Studi di Napoli Federico II Italy Phase Not Applicable Status not specified 0 66 2020-09-02
Effects of an online mindfulness-based intervention on quality of life and psychological symptoms in novel coronavirus pneumonia (COVID-19) patients in China: a randomized, controlled trial Coronavirus disease 19 infection, Psychiatric disorder, Sleep disorder Mindfulness-based interventions (MBIs) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chinese Academy of Medical Sciences & Peking Union Medical College China ChiCTR2000037524 Phase 0 Clinical Not yet recruiting 0 1600 Mingyu Si, Xiaoyou Su 2020-09-05
RNB COVID-19: Effect of Allo-vedic Preparation Raj Nirwan Bati (RNB) on Severe COVID-19 Patients Coronavirus disease 19 infection Raj Nirwan Bati alone, allopathic treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Uttar Pradesh University of Medical Sciences India 2020-08-31 CTRI/2020/08/027467, RNB COVID-19 Phase 3 Clinical Not yet recruiting 0 40 Dr Raj Kumar 2020-09-04
COVID-IHPBA: Outcomes of liver and pancreatic caner surgery during the COVID-19 pandemic Coronavirus disease 19 infection, Surgical procedure hepatobiliary surgery alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tata Memorial Hospital Ireland, Germany, France, US, India 2020-08-31 COVID-IHPBA, CTRI/2020/08/027466 Phase Not Applicable Not yet recruiting 0 1000 Shailesh V Shrikhande 2020-09-04
SARS-CoV-2 quick analysis in breath device Coronavirus disease 19 infection breath analysis test (BAT) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto De Tecnologia Do Parana of Brazil Brazil 2020-08-31 35555720.7.0000.5225, 4.234.085, RBR-72bg24, U1111-1257-4565 Phase Not Applicable Not yet recruiting 0 3000 Ana Paula Gori Palka, Meila Bastos de Almeida 2020-09-04
A Clinical Study to Evaluate MW33 Injection Coronavirus disease 19 infection MW33, Mabwell (Shanghai) Bioscience Co., Ltd. alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Mabwell (Shanghai) Bioscience Co Ltd Shanghai Public Health Clinical Center China 2020-08-07 2020-12-31 MW33-2020-CP101, NCT04533048 Phase 1 Clinical No longer recruiting 0 4 Months 42 Hongzhou LU 2020-09-05
COVID-19 Treatment in South Africa Coronavirus disease 19 infection Variable regimens including artesunate + amodiaquine combination tablet (malaria), DNDi/sanofi-aventis , favipiravir , nitazoxanide , paracetamol , pyronaridine + artesunate (oral), Medicines for Malaria Venture/Shin Poong/WHO , sofosbuvir + daclatasvir RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Shin Poong Pharmaceutical Co Ltd Medicines for Malaria Venture South Africa 2020-08-25 2021-01-31 NCT04532931, SP-PA-COV-202 Phase 2 Clinical Not yet recruiting 0 5 Months 250 Farouk Chughlay, MD, Francois Venter, PhD, Nomathemba Chandiwana, Sarah Arbe-Barnes, PhD 2020-09-03
Nasal Wash and Gargle to Mitigate COVID-19 Coronavirus disease 19 infection nasopharyngeal saline wash alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) India 2020-09-04 CTRI/2020/08/027465 Phase 1/Phase 2 Clinical Not yet recruiting 0 70 UDAY SANKAR CHATTERJEE 2020-09-03
Prevalence of COVID-19 Antibodies Kingman AZ Coronavirus disease 19 infection VITROS anti-SARS-CoV-2 IgG test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) US 2020-09-28 2020-12-28 KRMC 0205, NCT04533360 Phase Not Applicable Not yet recruiting 0 3 Months 3000 Anthony J Santarelli, PhD, John Ashurst, John V Ashurst, DO 2020-09-02
A Double-blind, Placebo-controlled Study to Assess the Efficacy and Safety of Oral Tafenoquine Versus Placebo in Patients With Mild-to-Moderate COVID-19 Disease Coronavirus disease 19 infection tafenoquine (oral tablet, malaria), 60° Pharmaceuticals/United States Army/Biocelect alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) 60° Pharmaceuticals LLC 2020-10-31 2021-02-28 NCT04533347, TQ 2020_06 Phase 2 Clinical Not yet recruiting 0 4 Months 275 Geoffrey Dow, PhD 2020-09-02
Study for predicting hypoxemia in COVID 19 patients on the basis of HRCT thorax findings with correlating the CT findings with SpO2 levels Coronavirus disease 19 infection, Hypoxia High-resolution CT (HRCT) alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kalinga Institute of Medical Sciences India 2020-08-31 CTRI/2020/08/027500 Phase Not Applicable Not yet recruiting 0 1000 Ajay Sharawat, Dr Kamal Kumar Sen 2020-09-03
Measures for COVID-19 in psychiatry Coronavirus disease 19 infection Tohoku University Graduate School Of Medicine Japanese Ministry of Health, Labor and Welfare Japan 2020-09-01 UMIN000041557 Phase Not Applicable Not yet recruiting 0 150 Hiroaki Tomita 2020-09-03
C-SMART (Arm 4): COVID-19 prevention and treatment in cancer arm 4: treatment among cancer patients with severe COVID-19 infection Coronavirus disease 19 infection, Viral pneumonia lenzilumab alone GM-CSF ligand inhibitor, Immunoglobulin G1 modulator, Immunoglobulin kappa modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Peter MacCallum Cancer Centre Australian Government Australia 2020-09-01 2021-12-01 ACTRN12620000844943, ANZCTR380424, C-SMART (Arm 4), U1111-1256-8488 Phase 3 Clinical Not yet recruiting 0 15 Months 72 Michelle Yong, Monica Slavin, Ronan Burder 2020-09-03
Biocontainment Device for Aerosol Generating Procedures Coronavirus disease 19 infection Biobox biocontainment-aerosol evacuation system (National Flag) alone, rapid sequence intubation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Pennsylvania Drexel University US 2020-09-30 2020-12-31 843373, NCT04532112 Phase Not Applicable Not yet recruiting 0 3 Months 150 Josh Atkins, MD PhD, Josh Atkins, Md, PhD, Liz Beothy, Michael A Kohanski, MD PhD, Michael A Kohanski, MD, PhD, Mitch Weinstein, MD 2020-09-01
Role of siddha medicine in the management of covid -19 Coronavirus disease 19 infection Variable regimens including >Thaleesadhi vadagam Mathirai , Adathodai manapagu , Amukkara Chooranam Mathirai , Brammanandha bairavam , Kaba Sura Kudineer Chooranam Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Indian Medicine and Homoeopathy India 2020-09-05 CTRI/2020/08/027499 Phase 2 Clinical Not yet recruiting 0 20 DrASuganya 2020-09-03
To identify the pathogenesis of COVID-19 at different stages with the help of Ayurveda Coronavirus disease 19 infection Shat - kriya kala alone, Vikar vighata - bhava, abhava ( Nidana , dosha , dushya paradigm ) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Ayurveda India 2020-09-06 CTRI/2020/08/027494 Phase Not Applicable Not yet recruiting 0 75 Dr Sisir Kumar Mandal, Dr Tanuja Nesari 2020-09-02
therapeutic effect of Rosa Damascena extract in treatment of COVID-19 Coronavirus disease 19 infection Rosa Damascena alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Semnan University of Medical Sciences Iran 2020-08-22 IR.SEMUMS.REC.1399.106, IRCT20200402046917N1 Phase Not Applicable Recruiting 0 20 Akram alizadeh, Maliheh Ghadir 2020-09-02
'COVID-19: Hotspot hospital ?- Epidemiological analysis time shifted antibody tests of hospital employees' Coronavirus disease 19 infection antibody test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Germany 2020-06-15 2020-478-f-S, DRKS00022941 Phase Not Applicable Recruiting 0 3000 Anke Hildebrandt 2020-09-02
Benefits of Siddha medicines in covid-19 positive patients Coronavirus disease 19 infection Adathodaimanapagu alone, AmukkaraChooranamMathirai alone, Brammanandhabairavam alone, KabaSuraKudineerChooranam alone, Thaleesadhivadagam alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Central Council for Research in Siddha India CTRI/2020/08/027491 Phase 2 Clinical Not yet recruiting 0 20 DrVVikramkumar, Sathya Rajeshwaran 2020-09-02
Growth Hormone in Obese Cases With COVID-19 Coronavirus disease 19 infection, Obesity recombinant growth hormone alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) ClinAmygate 2020-08-26 2020-10-20 NCT04532554, PR0015 Phase 4 Clinical Not yet recruiting 0 1 Month 20 2020-09-03
NEPSycon-COVID: Neurological manifestations of COVID-19 Coronavirus disease 19 infection Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) NHS NIHR Clinical Research Network China 2020-09-10 CTRI/2020/08/027490, NEPSycon-COVID Phase Not Applicable Not yet recruiting 0 200 Netravathi M, Ravi Vasanthapuram 2020-09-04
Mental health status, adjustment strategies due to covid19 pandemic and related factors Coronavirus disease 19 infection Adolescents (13-17 yrs), Young Adults (18-44 yrs) Kalinga Institute of Medical Sciences India 2020-09-06 CTRI/2020/08/027492 [ Phase not specified Not yet recruiting 0 400 Jayanti MIshra 2020-09-03
A phase I clinical study of new COVID-19 vaccine for the potential treatment of COVID-19 infection Coronavirus disease 19 infection new COVID-19 vaccine alone Vaccitech Ltd UK Government Phase 1 Clinical Planned 0 2020-09-01
A Study Looking at the Effectiveness and Safety of a COVID-19 Vaccine in South African Adults Coronavirus disease 19 infection NVX-CoV2373 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Novavax Inc Bill & Melinda Gates Foundation South Africa 2020-08-17 2021-11-30 2019NCOV-501, NCT04533399 Phase 2 Clinical Recruiting 0 15 Months 2904 Gregory M. Glenn, Rani Naidoo, Shabir A Madhi, MBBCH, PhD, Vivek Shinde, MD, MPH 2020-09-03
COVID-19 Testing Sample Acquisition Throughput and Efficiency (HexapodBooth) Coronavirus disease 19 infection Hexapod personal protective booth alone, nasal swab test alone Healthy volunteers accepted Massachusetts General Hospital US 2020-03-01 2020-09-30 NCT04532411, QI INITIATIVE Phase Not Applicable No longer recruiting 0 7 Months 25000 Kristian R. Olson 2020-09-03
Taste and Smell Impairment in Critically Ill Coronavirus Disease-19 Patients Coronavirus disease 19 infection, Dysomia, Taste disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sisli Etfal Hospital Turkey 2020-09-01 2020-09-20 3334-02, NCT04532632 Phase Not Applicable Not yet recruiting 0 40 Pinar Ay Sayin, mustafa altinay, pınar ay sayın 2020-09-03
PICS-COVID: Post-Intensive Care outcomes of patients with Corona virus Disease 2019 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Hospital Organization, Tokyo Medical Center Nestle Health Science Japan 2020-09-01 PICS-COVID, UMIN000041276 Phase Not Applicable Not yet recruiting 0 100 Junji Hatakeyama 2020-09-03
Leflunomide for the Treatment of Severe COVID-19 in Patients With a Concurrent Malignancy Cancer, Coronavirus disease 19 infection leflunomide alone, standard of care alone Dihydroorotate dehydrogenase inhibitor, Protein tyrosine kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) City of Hope Medical Center National Cancer Institute US 2020-09-18 2022-09-18 20291, NCI-2020-05746, NCT04532372, P30CA033572 Phase 1/Phase 2 Clinical Not yet recruiting 0 24 Months 30 Sanjeet S Dadwal, Sanjeet S. Dadwal 2020-09-01
A phase I/II, multi-national trial to evaluate DXP-604 in patients with mild to moderate COVID-19 Coronavirus disease 19 infection DXP-604 alone COVID19 Spike glycoprotein modulator BeiGene Co Ltd Phase 1/Phase 2 Clinical Planned 0 2020-09-03
Investigation for clinical utility of diagnostic reagents for COVID-19 Coronavirus disease 19 infection PCR testing alone, antigen testing alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Fujirebio Inc Japan 2020-09-01 UMIN000041402 Phase Not Applicable Not yet recruiting 0 300 Fumio Otsuka, Hideharu Hagiya 2020-09-03
Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Neutralizing Antibody in Healthy Subjects Coronavirus disease 19 infection DXP-593 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) BeiGene Co Ltd Australia 2020-09-08 2020-12-31 BGB-DXP593-101, NCT04532294 Phase 1 Clinical Recruiting 0 3 Months 30 BeiGene, Zhen Yao 2020-09-05
Effect of blood thinning medicine in COVID-19 infection Coronavirus disease 19 infection Aspirin alone, standard of care  alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Medical Sciences India 2021-06-15 CTRI/2020/08/027503 Phase 2 Clinical Not yet recruiting 0 60 Dr Souvik Maitra 2020-09-03
Evaluation of safety and efficacy of T-AYU-HM premium and onion steam vaporization/nebulization in COVID-19 patients Coronavirus disease 19 infection T-AYU-HM Premium  alone, onion steam vaporization/nebulization alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) India 2020-09-14 CTRI/2020/08/027477 Phase 2 Clinical Not yet recruiting 0 Dr Atul M Desai, Dr Hemshree Desai 2020-09-03
A Randomized Controlled Trial Of An Immunomodulator Mycobacterium w In Mild To Moderate COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia immunomodulator mycobacterium w alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Cadila Pharmaceuticals Ltd India 2020-09-01 CTRI/2020/08/027475 Phase 3 Clinical Not yet recruiting 0 30 Dr Shweta Ram Chandankhede 2020-09-03
Oxygen requirement in COVID patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sri Ramachandra University India 2020-08-31 CTRI/2020/08/027460 Phase Not Applicable Not yet recruiting 0 100 Priyadarshini Varadaraj 2020-09-03
To study about the outcome of COVID-19 on Diabetes patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sri Ramachandra Institute of Higher Education and Research India 2020-09-01 CTRI/2020/08/027459 Phase Not Applicable Not yet recruiting 0 200 DR Aiswarya M Nair 2020-09-03
Comparison two types of artificial respiration in severe COVID-19 patients Coronavirus disease 19 infection, Respiratory distress syndrome Airway Pressure Release Ventilation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Medical Sciences India 2020-09-10 CTRI/2020/08/027502 Phase Not Applicable Not yet recruiting 0 216 Dr Souvik Maitra 2020-09-04
Anesthesia practices and safety of caregivers during the covid 19 pandemic Coronavirus disease 19 infection Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Max Super Speciality Hospital India 2020-09-01 CTRI/2020/08/027470 Phase Not Applicable Not yet recruiting 0 300 Nambiath Sujata 2020-09-03
Laboratory predictors and covid Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sri Ramachandra Medical College, Hospital & Research institute India 2020-08-31 CTRI/2020/08/027458 Phase Not Applicable Not yet recruiting 0 850 Dr Vaasanthi 2020-09-03
A survey to understand the opinion among doctors regarding usage of personal protective equipment Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Karnataka Institute of Medical Sciences India 2020-09-01 CTRI/2020/08/027469 Phase Not Applicable Not yet recruiting 0 1000 Milon Vasant Mitragotri 2020-09-03
Covid Nuvastatic: A study to assess aspects of safety and efficacy of Nuvastatic™ (C5OSEE5050ESA) as an immunomodulator supportive treatment to the standard care of treatment in Covid 19 patients Coronavirus disease 19 infection Nuvastatic alone, standard care of treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Natureceuticals Sdn Bhd India 2020-09-10 BIAG-CSP-037, CTRI/2020/08/027501, Covid Nuvastatic Phase 2 Clinical Not yet recruiting 0 10 Divya C, Dr Sanjay Vinaik, Shalini Dayananda 2020-09-03
HRCT chest imaging in pediartic, adult and geriatric patients with COVID-19 infection Coronavirus disease 19 infection Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kalinga Institute of Medical Sciences India 2020-09-01 CTRI/2020/08/027468 Phase Not Applicable Not yet recruiting 0 900 Dr Mayank Goyal, DrCol Kamal K Sen 2020-09-03
BG-CoV: Association of COVID-19 severity with blood group antigens Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Medical Sciences India 2020-09-01 BG-CoV, CTRI/2020/08/027471 Phase Not Applicable Not yet recruiting 0 200 Diptiranjan Rout 2020-09-03
A medical records based research on the establishment of a precise treatment system for novel coronavirus pneumonia (COVID-19) from the perspective of ''damp-and-heat epidemic'' Coronavirus disease 19 infection traditional chinese medicine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shanghai Traditional Chinese Medicine Hospital Shanghai shen-kang hospital clinical development center China 2020-10-01 2023-10-01 ChiCTR2000037342 Phase Not Applicable Not yet recruiting 0 36 Months 300 Shi Kehua 2020-09-02
Respiratory Syncytial Virus Infection May be More Dangerous in Neonate Coronavirus disease 19 infection, Respiratory syncytial virus infection Bio-Speedy qPCR detection kit alone, Bosphore Respiratory Pathogens Panel Kit V4 alone, biological sampling alone Newborn Infants (up to 5 months) Dr. Behcet Uz Children's Hospital Turkey 2020-03-01 2020-08-31 2020/522, NCT04531735 Phase Not Applicable No longer recruiting 0 6 Months 28 Senem Alkan Özdemir 2020-09-02
Camostat and Artemisia Annua Versus Placebo in COVID-19 Outpatients Coronavirus disease 19 infection, Viral pneumonia Artemisia annua alone, camostat mesylate alone Serine protease inhibitor, Transmembrane serine protease 2 inhibitor, Trypsin inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto Nacional de Ciencias Medicas y Nutricion Hospital General Dr. Manuel Gea González, Hospital General de Mexico, Instituto Nacional de Cardiologia Ignacio Chavez Mexico 2020-09-30 2021-02-28 3421, NCT04530617 Phase 2 Clinical Not yet recruiting 0 5 Months 360 David Kershenobich Stalnikowitz, MD, Jose G Gotes Palazuelos, MD 2020-09-04
Immune Cell Subgroups in Covid 19 Patients Coronavirus disease 19 infection, Lymphocytopenia, Respiratory failure Flow cytometric analysis alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Istanbul Training and Research Hospital Turkey 2020-08-15 2020-09-15 COVID CELL, NCT04531319 Phase Not Applicable Recruiting 0 1 Month 60 Tahir Talat Yurttas, MD, Ufuk Oguz Idiz, Assoc. Prof 2020-09-01
Timing of Corticosteroids in COVID-19 Coronavirus disease 19 infection dexamethasone alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) ClinAmygate Egypt 2020-08-26 2020-11-01 NCT04530409, PR0012 Phase 4 Clinical Not yet recruiting 0 2 Months 450 Emad Roushdy, Dr 2020-09-02
Efficacy and Safety of Recovered Covid-19 Plasma Transfusion to Covid-19 Severly Ill Patients Coronavirus disease 19 infection recovered Covid-19 patient plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) South Valley University Egypt 2020-05-29 2020-09-01 NCT04530370, OSSAMAHAMDYRESEARCHER7 Phase 0 Clinical Recruiting 0 3 Months 30 Gad S Gad, MD, Gad s Gad, MD, Ossama Hamdy Salman, ossama h salman, MD,PhD 2020-09-01
Outpatient Use of Ivermectin in COVID-19 Coronavirus disease 19 infection ivermectin alone Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Temple University US 2020-10-01 2021-12-31 1285242, NCT04530474 Phase 3 Clinical Not yet recruiting 0 15 Months 200 Derek Isenberg, MD, Nina Gentile, MD 2020-09-01
Back to School COVID-19 Simulation Study Coronavirus disease 19 infection Face mask alone Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Hospital for Sick Children Canada 2020-08-10 2020-12-31 1000071861, NCT04531254 Phase Not Applicable No longer recruiting 1 4 Months 240 Michelle Science 2020-09-02
EPICOVID-PAHANG: Epidemiological study of COVID-19 in Pahang Coronavirus disease 19 infection Malaysia 2020-08-28 2020-12-31 56085, EPICOVID-PAHANG, NMRR-20-1825-56085 Phase Not Applicable Status not specified 1 4 Months Dr Che Asiah binti Taib, Dr muhammad 'adil bin zainal abidin 2020-09-01
Drug utilization for Covid-19 Coronavirus disease 19 infection International Islamic University Malaysia Malaysia 2020-10-01 2021-09-30 56013, NMRR-20-1823-56013 Phase Not Applicable Status not specified 1 12 Months Assoc Prof Dr Che Suraya Haji Mohd Zin 2020-09-01
RESIST: Clinical Trial of Efficacy, Safety, and Immunogenicity of Gam-COVID-Vac Vaccine Against COVID-19 Coronavirus disease 19 infection Sputnik V alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Health Ministry of the Russian Federation Collaborator Crocus Medical B.V Russian Federation 2020-08-31 2021-05-01 04-GAM-COVID-VAC-2020, NCT04530396, RESIST Phase 3 Clinical Not yet recruiting 0 8 Months 40000 Boris Rodionov, MD, Elena Nurmukhametova, MD, PhD, Elena Smolyarchuk, MD, PhD, Inna Dolzhikova, PhD, Irina Gagarina, MD, Irina Shestakova, MD, Marina Rusanova, MD, Sergey Fitilev, MD, Tatiana Shimonova, MD 2020-09-03
Glycemic Control Among Children and Adolescents With Type 1 Diabetes During COVID-19 Pandemic in Egypt Coronavirus disease 19 infection, Insulin dependent diabetes Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Ain Shams University Egypt 2020-07-07 2020-08-31 FMASU P66/2020, NCT04531111 Phase Not Applicable Recruiting 0 1 Month 150 Khadiga Eltonbary, Yasmine Ehenawyl, Yasmine Elhenawy 2020-09-01
Serological Profile of SARS CoV2 in Patients With Systemic Diseases Behcets disease, Coronavirus disease 19 infection, Myopathy, Rheumatoid arthritis, Sarcoidosis, Sjoegrens syndrome, Spondylarthritis, Systemic lupus erythematosus RT-PCR alone, biological sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopital Militaire Principal d'instruction de Tunis Tunisia 2020-06-01 2021-01-31 NCT04530461, UR17DN02-002 Phase Not Applicable Recruiting 0 8 Months 200 Faida Ajili, MD, Rim Dhahri, MD, Sameh Sayahi, MD, faida agili 2020-09-03
PEP-CoV: PEP Flute-selfcare in COVID-19 Coronavirus disease 19 infection, Respiratory disease COPD assessment test alone, daily text messaging alone, positive expiratory pressure flute alone, video guidance alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bispebjerg Hospital HS Hvidovre Hospital Denmark 2020-09-01 2021-04-30 0211-00023B, NCT04530435, PEP-CoV Phase Not Applicable Not yet recruiting 0 8 Months 400 Annette Mollerup, PhD, Berit L. Heitmann, Professor, Ph.D, Sofus C. Larsen, PhD 2020-09-02
PROTECT-COVID-19-US: Prevention of Severe SARS-CoV-2 Infection in Hospitalized Patients With COVID-19 Acute lung injury, Coronavirus disease 19 infection, Lung disease conestat alfa alone, standard of care alone Complement C1s subcomponent inhibitor, Kallikrein modulator, Mannan-binding lectin serine protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Pharming Technologies BV US 2020-09-15 2021-03-31 C1 6201, NCT04530136, PROTECT-COVID-19-US Phase 2 Clinical Not yet recruiting 0 6 Months 120 Anurag Relan, MD, Jonathan Bernstein, MD, Leisa Waynick, BSBA 2020-09-03
COVID-19 Saliva Test Research Study Coronavirus disease 19 infection Chronomics test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chronomics Ltd UK 2020-06-29 2020-09-29 283560, NCT04531501 Phase Not Applicable Recruiting 2 3 Months 400 Hannah Howlett, Janet Forkes, Sana Wahid 2020-09-02
SAINT-PERU: Randomized, phase IIa clinical trial to compare the efficacy of ivermectin versus placebo to obtain negative PCR results in patients with early phase COVID-19 Coronavirus disease 19 infection ivermectin alone Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidad Peruana Cayetano Heredia Peru 2020-09-07 PER-034-20, SAINT-PERU Phase 2a Clinical Not yet recruiting 1 68 Carlos Chaccour Díaz, César Cárcamo Cavagnaro, César Ugarte Gil, German Javier Malaga Rodrìguez, Germán Málaga Rodríguez, Hansel Kevin Mundaca Hurtado, PATRICIA JANNET GARCÍA FUNEGRA, Patricia Hilda León Paredes, Patricia Jannet García Funegra 2020-09-02
AUNA 20-01: Phase II study of efficacy and safety of plasma from convalescent patients with COVID-19 in patients with moderate disease Coronavirus disease 19 infection convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Peru 2020-07-06 AUNA 20-01, PER-031-20 Phase 2 Clinical Not yet recruiting 1 50 Alejandro DALY TURCKE, Alfredo Eric Goytendia Cortez, Antonio Alfredo Carrasco Yalan, INA NOELIA PÉREZ HUAYNALAYA, Ina Noelia Pérez Huaynalaya, Joseph Arturo Pinto Oblitas, Maria Consuelo Requena Medina, Victor Romario Pizarro Herrera 2020-09-02
A global, randomised, placebo-controlled Phase II trial of LYT-100 for the treatement of serious respiratory complications linked to inflammation and fibrosis that persist following the resolution of SARS-CoV-2 (COVID-19) infection Coronavirus disease 19 infection, Fibrosis, Respiratory disease, Respiratory tract inflammation deupirfenidone alone PDGF receptor antagonist, TGF beta receptor antagonist, p38 MAP kinase inhibitor PureTech Health Plc 2020-09-30 Phase 2 Clinical Planned 0 2020-08-31
Randomized, Blind, Placebo-controlled I/II Phase QAZCOVID-IN- COVID-19 Coronavirus disease 19 infection QazCovid-in COVID-19 inactivated vaccine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Research Institute for Biological Safety Problems, RIBSP Ministry of Health of the Republic of Kazakhstan Kazakhstan 2020-09-01 2021-04-30 NCT04530357, QAZCOV-I/II-01/2020 Phase 1/Phase 2 Clinical Recruiting 0 8 Months 244 Berik Khairullin, PhD, Gulbanu Sarsenbayeva, MB, Ilyas Kulmagambetov, PhD 2020-09-02
The Effect of Melatonin and Vitamin C on COVID-19 Coronavirus disease 19 infection ascorbic acid alone, melatonin alone Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Lancaster General Hospital US 2020-09-01 2021-12-01 2020-68, NCT04530539 Phase Not Applicable Not yet recruiting 0 15 Months 150 Ca F, Corey Fogleman, Tawnya Vernon 2020-09-02
A phase I clinical trial of DIOS-CoVax2 for the potential treatment of COVID-19 infection Coronavirus disease 19 infection DIOS-CoVax2 alone DIOSynVax Ltd, University of Cambridge Technology Strategy Board, University Hospital Southampton NHS Foundation Trust UK Phase 1 Clinical Planned 1 2020-08-31
A Phase I/II clinical trial of VBI-2902 for the treatment of Coronavirus disease 19 infection Coronavirus disease 19 infection VBI-2902 alone COVID19 Spike glycoprotein modulator VBI Vaccines Inc 2020-12-31 Phase 1/Phase 2 Clinical Planned 0 2020-09-02
Phase I Trial of a Recombinant SARS-CoV-2 Vaccine (Sf9 Cell) Coronavirus disease 19 infection Sf9 Cell (Jiangsu Province Centers for Disease Control and Prevention) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry Jiangsu Province Centers for Disease Control and Prevention West China Hospital China 2020-08-28 2021-08-28 ChiCTR2000037518, JSVCT098, NCT04530656 Phase 1 Clinical Not yet recruiting 1 12 Months 168 Fanyue Meng, Doctor, Fengcai Zhu, Doctor, Siyue Jia, PhD, Wei Wang 2020-09-04
SENTINEL: Selective Estrogen Modulation and Melatonin in Early COVID-19 Coronavirus disease 19 infection melatonin plus toremifene Estrogen receptor modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cleveland Clinic Foundation US 2020-09-30 2021-09-30 20-842, NCT04531748, SENTINEL Phase 2 Clinical Not yet recruiting 1 12 Months 390 Kylie Phillips, Reena Mehra, MD, Samantha Wells 2020-09-02
Coronavirus-Induced Acute Kidney Injury: Prevention Using Urine Alkalinization Coronavirus disease 19 infection, Renal injury sodium bicarbonate alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) West Virginia University US 2020-08-31 2021-03-31 NCT04530448, WVU PROTOCOL #2005006707 Phase 4 Clinical Not yet recruiting 1 7 Months 40 Ankit Sakhuja, Ankit Sakhuja, MD, Lisa Fornaresio, PhD 2020-09-01
Effects of Sevoflurane on Extravascular Lung Water and Pulmonary Vascular Permeability in Patients With ARDS Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure AnaConDa-S, Sedana Medical alone, remifentanil plus sevoflurane Opioid receptor mu agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopital de Bicetre France 2020-11-30 2022-11-30 BICETREH, NCT04530188 Phase 3 Clinical Not yet recruiting 1 24 Months 68 Christopher Lai, principal investigator, Christopher lai, MD, Xavier Monnet, MD, PhD 2020-09-02
Efficacy of Sofosbuvir Plus Ledipasvir in Egyptian Patients With COVID-19 Compared to Standard Treatment Coronavirus disease 19 infection, Viral pneumonia Variable regimens including ceftriaxone , enoxaparin sodium , methylprednisolone , sofosbuvir + ledipasvir Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Egypt 2020-04-15 2020-07-23 14, NCT04530422 Phase 3 Clinical Completed 1 3 Months 250 Mohamed Abdelsalam El-Gohary 2020-09-03
Cytokine Status of Covid-19 Patients Coronavirus disease 19 infection, Lymphocytopenia, Respiratory failure flow cytometry alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Istanbul Training and Research Hospital Turkey 2020-09-01 2020-10-15 COVID CYTOKINE, NCT04531345 Phase Not Applicable Not yet recruiting 1 1 Month 50 Tahir Talat Yurttas, MD, Ufuk Oguz Idiz, Assoc. Prof 2020-09-01
CORE Study COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto D'Or de Pesquisa UK, Switzerland, Brazil 2020-03-02 2021-09-30 29496920.8.0000.5262, NCT04531202 Phase Not Applicable Recruiting 3 18 Months 2000 Fernando Bozza, phD 2020-09-02
COVID-19 In-vitro Diagnostic Test and Androgen Receptor Gene Expression Coronavirus disease 19 infection COVID-19 androgen sensitivity test alone Healthy volunteers accepted, Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of California Irvine Applied Biology Inc US 2020-08-13 2021-08-31 2020-5907, NCT04530500 Phase Not Applicable Recruiting 2 12 Months 200 Natasha Mesinkovska, MD, PhD 2020-09-02
NEBUHEPA: Nebulized Heparin in Severe Acute Respiratory Syndrome COVID-19 Coronavirus disease 19 infection, Inflammatory disease, Lung disease, Viral pneumonia enoxaparin sodium plus heparin sodium Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Clinica San Camilo Argentina 2020-06-01 2021-06-01 CSANCAMILO, NCT04530578, NEBUHEPA Phase 4 Clinical Recruiting 1 12 Months 200 ALICIA B VILASECA, DR, RUBEN F BARBERA, DR, Ruben F Barbera, DR 2020-09-02
Defibrotide Therapy for SARS-CoV2 (COVID-19) Acute Respiratory Distress Syndrome (ARDS) Coronavirus disease 19 infection, Lung disease, Respiratory distress syndrome, Viral pneumonia defibrotide (iv, veno-occlusive disease), Gentium alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Michigan Jazz Pharmaceuticals plc US 2020-09-30 2021-07-31 HUM00182089, NCT04530604 Phase 1 Clinical Not yet recruiting 1 10 Months 12 Gregory Yanik, MD, Mary Maliarik, PhD 2020-09-03
A trial to evaluate adjuvanted peptide vaccine (microsphere formulation, COVID-19), University of Saskatchewan/VIDO-InterVac/ZYUS Life Sciences for the prevention of COVID-19 Coronavirus disease 19 infection adjuvanted peptide vaccine (microsphere formulation, COVID-19), University of Saskatchewan/VIDO-InterVac/ZYUS Life Sciences alone Government of Saskatchewan, VIDO-InterVac Canadian Government 2020-12-31 Phase Not Applicable Planned 0 2020-09-02
COVIDRIC: COVID-19 in Rheumatic Inflammatory Diseases Under Immuno-suppressive Drugs Coronavirus disease 19 infection, Rheumatoid arthritis, Spondylarthritis immuno-suppressive drug therapy alone, serological test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Montpellier Societe Francaise de Rhumatologie France 2020-10-20 2024-07-31 COVIDRIC, NCT04530682, RECHMPL20_0409, UF8074 Phase Not Applicable Not yet recruiting 1 45 Months 5000 Jacques MOREL, MD, PhD 2020-09-03
COVID-19 severity in Elderly people aged > 60 years Coronavirus disease 19 infection Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sri Ramachandra Institute of Higher Education and Research India 2020-08-30 CTRI/2020/08/027435 Phase Not Applicable Not yet recruiting 1 200 Dr Viswanathan P 2020-09-03
A Survey to Assess the Impact of the COVID-19 Pandemic and Resultant Lockdown Measures on Ongoing Clinical Trials in India Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) India 2020-09-06 CTRI/2020/08/027420, Survey-IND-01-2020 Phase Not Applicable Not yet recruiting 1 130 Jayanti Gupta, Rakesh Dadhania 2020-08-31
A case report to evaluate the efficacy of methylprednisolone in patients with immune-related pneumonitis and COVID-19 infection Coronavirus disease 19 infection, Pneumonia methylprednisolone alone Sociedade Beneficente Israelita Brasileira Hospital Albert Einsten Phase Not Applicable Status not specified 0 2 2020-09-01
Prevalence of and Factors Associated with Burnout among Philippine Radiation Oncology Residents During the COVID-19 Pandemic Coronavirus disease 19 infection Philippine General Hospital Philippines 2020-07-26 2020-08-09 PHRR200820-002847 Phase Not Applicable Completed 1 Aedrian A. Abrilla, Johanna Patricia Adevoso-Cañal, MD, MHA, MSc, Jose Miguel C. Callueng, MD 2020-09-01
Herd immunity level to COVID-19 as an indicator of the epidemic progression in Thailand Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) HRH Princess Chulabhorn College of Medical Science, Chulabhorn Royal Academy Thailand 2020-07-07 TCTR20200822003 Phase Not Applicable Recruiting 1 15000 Chirayu Auewarakul 2020-09-01
Offline versus online presentation: benefits and challenges during covid pandemic Coronavirus disease 19 infection Offline presentation alone, Online presentation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Manipal Academy of Higher Education Kasturba Medical College, Manipal India 2020-09-15 CTRI/2020/08/027418 Phase Not Applicable Not yet recruiting 1 225 Vijetha Shenoy Belle 2020-08-31
Covid-19 with hypertension is responsible for death of patients Coronavirus disease 19 infection, Hypertension Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gujarat Cancer Society Medical college hospital and research centre India 2020-08-31 CTRI/2020/08/027407 Phase Not Applicable Not yet recruiting 1 200 Dr Mahipalsinh Raol 2020-08-31
A retrospective assessment of risk factors for COVID- 19 in health care workers Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Lok Nayak Hospital, Maulana Azad Medical College India 2020-09-07 CTRI/2020/08/027403 Phase Not Applicable Not yet recruiting 1 90 DrSukhyanti Kerai 2020-09-01
Seroprevalence surveillance of covid-19 among population in Johar- 2020 Coronavirus disease 19 infection Malaysia 2020-09-01 NMRR-20-1814-55673 Phase not specified Status not specified 1 Dr Jeyanthini a/p Sathasivam 2020-09-01
A retrospective study to evaluate cumulative incidence of Covid-19 and its treatment outcome, mortality and associated risk factors in lung cancer patients Coronavirus disease 19 infection, Lung tumor azithromycin plus hydroxychloroquine Hospital Universitario Infanta Leonor Spain Phase Not Applicable Status not specified 1 320000 2020-08-31
Realtion of Catalytic iron and Hepcidin with Poor Outcomes in COVID-19 patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) KEM Hospital and Research Center India 2020-09-07 CTRI/2020/08/027419 Phase Not Applicable Not yet recruiting 1 49 Dr Vipul Chakurkar 2020-08-31
An observational, retrospective study on the association between the use of angiotensin-converting enzyme inhibitors/angiotensinogen receptor blockers and in-hospital mortality of hypertensive patients diagnosed with COVID-19 pneumonia Coronavirus disease 19 infection, Hypertension, Viral pneumonia angiotensin-converting enzyme inhibitors alone, angiotensinogen receptor blockers alone Saglik bilimleri universtesi Phase Not Applicable Status not specified 0 74 2020-08-31
S-Nitrosylation Therapy of COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome S-nitrosothiol alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Japanese Ancestry University Hospitals of Cleveland Case Western Reserve University US 2020-10-31 2021-04-30 NCT04528771, STUDY20200453 Phase 1b Clinical Not yet recruiting 1 6 Months 21 James Reynolds, PhD, Olivia Giddings, MD, Rana Hejal, MD, Robert Schilz, DO, PhD 2020-09-01
A Case Report of Thrombosis and Bleeding as presentation of COVID-19 infection with polycythemia vera Bleeding, Coronavirus disease 19 infection, Polycythemia vera Sarawak General Hospital Malaysia 2020-08-25 NMRR-20-1803-56251 Phase not specified Status not specified 1 Dr Chow Lai Chee 2020-09-02
The technical specification of precise drug therapy and the systematic study of novel Coronavirus inactivation procedure for biological samples Coronavirus disease 19 infection genetic testing alone Shanghai Jiao Tong University China 2020-10-01 2021-09-30 ChiCTR2000037078 Phase 0 Clinical Not yet recruiting 1 12 Months 100 guorong fan, zhenghua wu 2020-08-31
IVERCORCOVID19: Ivermectin to Prevent Hospitalizations in COVID-19 Coronavirus disease 19 infection ivermectin alone Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institute of Cardiology of Corrientes Argentina 2020-08-19 2021-01-31 IVERCORCOVID19, IVERCORCOVID19MSPICC, NCT04529525 Phase 2/Phase 3 Clinical Recruiting 1 5 Months 500 Angelina Bobadilla, Dra, Antonia Aquino, Claudia Campias, Diego Farizano, Evangelina Chaparro Campias, Fabian Plano, Dr, Fernanda Medina, Fernando Achinelli, Dr, Gerardo Andino, Hector A Gugliermone, Jorge Ojeda, Dr, Julio Vallejos, Dr, Maria Bangher, Dra, Natalia E Ruiz Diaz, Pablo Kawerin, Rodrigo Zoni, Dr, Silvina Dellamea, Silvina Villamandos, Dra, Victor Flores 2020-09-01
Our experience with emergency ophthalmic surgery at Hospital Kuala Lumpur (HKL) during the COVID-19 pandemi Coronavirus disease 19 infection, Ocular disease Hospital Kuala Lumpur Malaysia 2020-08-20 2020-12-31 NMRR-20-1790-56127 Phase not specified Status not specified 1 4 Months Dr Seow Shu Yee 2020-08-31
Application of IL-18/IL-18BP in diagnosis and treatment of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection IL-18BP antagonist therapy alone Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shanghai Public Health Clinical Center China 2020-10-30 2022-10-30 ChiCTR2000036661 Phase 0 Clinical Not yet recruiting 1 24 Months 30 Mingquan Guo 2020-09-02
Palliative care expertise as an integral part of pandemic management (COVID-19) Coronavirus disease 19 infection Universitätsklinikum Freiburg, Klinik für Palliativmedizin Germany 2020-05-29 299/20, DRKS00022473 Phase Not Applicable Recruiting 1 30 Katharina Seibel 2020-08-31
Establishment of imaging diagnostic models for novel coronavirus pneumonia (COVID-19) and related brain injury based on artificial intelligence Coronavirus disease 19 infection, Viral pneumonia Huashan Hospital, Shanghai shen-kang hospital clinical development center China 2020-10-01 2022-09-30 ChiCTR2000036849 Phase 0 Clinical Not yet recruiting 1 24 Months 5000 Bo Yin 2020-08-31
Multi-center, Randomized, Double-Blind and Placebo-Controlled Clinical Trial on the Efficacy and Safety of Jinhua Qinggan Granules (JHQG) for the Treatment of COVID-19 Patient Coronavirus disease 19 infection, Viral pneumonia Jinhua Qinggan Granules alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Beijing Hospital of Traditional Chinese Medicine affiliated to Capital Medical University, University Of Karachi Pakistan 2020-04-24 2021-04-30 ChiCTR2000036871, ChiMCTR2000003697 Phase 4 Clinical Not yet recruiting 2 12 Months Prof. Dr M. Raza Shah T.I./Liu Qing Quan, Xin Li 2020-08-31
Convalescent Plasma for Treating Patients With COVID-19 Pneumonia Without Indication of Ventilatory Support Coronavirus disease 19 infection, Viral pneumonia convalescent plasma alone, standard treatment alone Instituto D'Or de Pesquisa Hospital do Coracao Brazil 2020-08-18 2020-12-31 34651120.8.0000.5249, NCT04528368 Phase 2 Clinical Recruiting 1 4 Months 60 Abel Costa Neto, MD, Eduardo M Rego, MD, PhD 2020-08-28
A case report of 18F-fluorodeoxyglucose uptake in patient with asymptomatic severe acute respiratory syndrome coronavirus 2 (coronavirus disease 2019) referred to positron emission tomography/computed tomography for non small cell lung cancer restaging Coronavirus disease 19 infection, Non-small-cell lung cancer, SARS coronavirus infection 18F-fluorodeoxyglucose alone, Positron emission tomography/computed tomography alone Male University of Turin Italy Phase Not Applicable Status not specified 1 1 2020-08-31
Presentation, Clinical Course and Patterns of Myocardial Damage Due to Viral Myocarditis Adenovirus infection, Coronavirus disease 19 infection, Enterovirus infection, Heart injury, Hepatitis B virus infection, Hepatitis C virus infection, Myocarditis, Parvovirus infection 12 lead ECG alone, ELIZA alone, PCR alone, cardiac MRI alone, coronary angiography alone, echocardiography alone, endomyocardial biopsy alone, immunohistochemistry alone, nucleic acid extraction alone, quantitative real-time PCR alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assiut University Egypt 2020-10-01 2021-03-01 NCT04527835, VIRAL MYOCARDITIS Phase Not Applicable Recruiting 1 5 Months 18 Amr Elbadry, lecturer, Amr yousif, professor, Ayman khairy, assistant professor, Ayman khairy, professor, Shery Asaad, Resident, Shery Asaad, resident, Shery Refaat Asaad 2020-09-03
QUICK study: A multicenter, retrospective, longitudinal, observational study about Quarantine and social Isolation for COVID-19 and its impact on Kawasaki disease Adenovirus infection, Coronavirus disease 19 infection, Gastrointestinal infection, Herpesvirus type 6 infection, Influenza virus infection, Kawasaki disease, Metapneumovirus infection, Respiratory syncytial virus infection, Respiratory tract infection, Skin infection, Streptococcus pyogenes infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Japanese Ancestry Fukuoka Children's Hospital, Kawasaki disease center Japan 2020-06-01 2020-08-10 QUICK study, UMIN000041579 Phase Not Applicable No longer recruiting 5 2 Months 4500 Kenji Furuno, Toshiro Hara 2020-09-02
Development of Ethical and Operational Guidelines for the Delivery of Surgical Care in a COVID-19 Referral Hospital Coronavirus disease 19 infection surgical care alone Philippine General Hospital Philippines 2020-06-01 2020-08-01 PHRR200820-002855 Phase Not Applicable No longer recruiting 1 2 Months Alvin B. Caballes, MD, MDE, MPP, Brent Andrew G. Viray, MD, MPM-HSD, Claudine Lukban, MD, Marie Carmela Lapitan, Maureen Villanueva, MD, Samantha Siahetong, MD 2020-08-31
Use of emergency medical services: experience 100 days after first case of COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Khon Kaen University Thailand 2020-08-21 TCTR20200822002 Phase Not Applicable Recruiting 1 545 Korakot Apiratwarakul 2020-08-31
THINC: Evaluation of the Efficacy and Safety of Treatments for Patients Hospitalized for COVID-19 Infection Without Signs of Acute Respiratory Failure, in Tunisia Bronchitis, Coronavirus disease 19 infection, Lower respiratory tract infection, Respiratory failure, Viral pneumonia usual standard treatment alone, Variable regimens including azithromycin , doxycycline hyclate , hydroxychloroquine , zinc Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Abderrahmane Mami Hospital Datametrix AG, Eshmoun Clinical Research Centre Tunisia 2020-05-15 2020-07-15 ECC2020-05, NCT04528927, THINC Phase 3 Clinical Terminated 1 2 Months Dr Jalila Ben Khelil 2020-09-02
PRESAGE: Study of Seroprevalence Vis-a-vis SARS-CoV2 and Correlation With Clinical Forms of COVID-19 in Patients Followed in Pneumology in the Cluster Area of the Grand-Est Region (Strasbourg University Hospital) Coronavirus disease 19 infection, Respiratory failure Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopitaux Universitaires de Strasbourg France 2020-09-30 2022-12-31 7879, NCT04528901, PRESAGE Phase Not Applicable Not yet recruiting 1 27 Months 1080 Celine MASCAUX 2020-09-03
Response of Korean Medicine Hospital to COVID-19 Coronavirus disease 19 infection Healthy volunteers accepted Jaseng Hospital of Oriental Medicine Jaseng Medical Academy South Korea 2020-06-10 2020-08-10 JMA-CT-2020-01, NCT04529447 Phase Not Applicable Completed 1 2 Months 485 Jinho Lee, KMD, Ph.D. 2020-08-28
EARSATS-19: In-ear Measurement of Blood Oxygen Saturation in COVID-19 Follow-up Coronavirus disease 19 infection, Lung disease ear plug type pulse oximeter probe alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Imperial College London UK 2020-08-26 2020-08-26 285603, EARSATS-19, NCT04529408 Phase Not Applicable Recruiting 1 60 Cheuk F Wong, Nicholas Peters, MD, Patrik Bachtiger, Patrik Bachtiger, MBBS 2020-08-31
An FDA expanded access programm/compassionate use program for bucillamine in COVID-19 Coronavirus disease 19 infection repurposed formulation of bucillamine (gout/cystinuria/Wilson disease/influenza/COVID-19), Revive Therapeutics alone Xanthine oxidase inhibitor Revive Therapeutics Ltd Phase Not Applicable Planned 0 2020-08-28
Role of Siddha medicine in the management of Covid-19 positive patients Coronavirus disease 19 infection Variable regimens including adathodai mangapu , ammakura choornam , bramhananda bairavam , kapa sura kudineer , thalasathy vadagam Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Siddha Central Research Institute India 2020-09-03 CTRI/2020/08/027397 Phase 2 Clinical Not yet recruiting 1 20 DRSTHILLAIVANAN 2020-08-31
A phase III clinical study to assess CT-P59 in the treatment of patients with moderate-to-severe SARS-CoV-2 infection Coronavirus disease 19 infection CT-P59 alone COVID19 Spike glycoprotein inhibitor, Moesin modulator Celltrion Healthcare Co Ltd 2020-12-31 Phase 3 Clinical Planned 0 2020-08-28
Mental health of pregnant women Covid-19 pandemic Coronavirus disease 19 infection Young Adults (18-44 yrs) All India Institute of Medical Sciences India 2020-09-03 CTRI/2020/08/027396 Phase Not Applicable Not yet recruiting 1 100 Dr Vidushi Kulshrestha 2020-08-31
A phase I clinical study to assess safety, tolerability, efficacy, pharmacokinetics and immunogenicity of CT-P59 in patients with mild symptoms of SARS-CoV-2 infection Coronavirus disease 19 infection CT-P59 alone COVID19 Spike glycoprotein inhibitor, Moesin modulator Celltrion Healthcare Co Ltd South Korea 2020-08-26 Phase 1 Clinical Recruiting 1 2020-08-28
TRACERx Renal CAPTURE: TRACERx Renal CAPTURE Sub-study Coronavirus disease 19 infection, Renal cell carcinoma Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The Royal Marsden NHS Trust The Francis Crick Institute UK 2012-02-05 2023-09-01 CCR 3723, NCT03226886, TRACERx Renal CAPTURE Phase Not Applicable Recruiting 4 138 Months 360 Dr Maxine Tran, Dr Sarah Rudman, Ellie Carlyle, Prof William Drake, Samra Turajlic, Steve Leung 2020-09-03
Study of Radiological Imaging in COVID Patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sri Ramachandra University India 2020-09-01 CTRI/2020/08/027395 Phase Not Applicable Not yet recruiting 1 1000 Dr Swathy Moorthy 2020-08-31
Assessment of response of ivermectin on virological clearance in COVID-19 patients Coronavirus disease 19 infection ivermectin alone Chloride channel modulator Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Maulana Azad Medical College India 2020-09-02 CTRI/2020/08/027394 Phase 2 Clinical Not yet recruiting 1 56 ROMIT SAXENA 2020-08-31
Evaluating an Online Adjunctive Support Following Intensive Services (OASIS) Strategy for Youth With Selective Mutism Anxiety disorder, Coronavirus disease 19 infection remote caregiver training alone, remote intensive group behavioral treatment alone Preschool Children (2-5 yrs), Children (6-12 yrs) Florida International University US 2020-03-06 2020-12-01 20-0010, NCT04291638 Phase Not Applicable No longer recruiting 1 8 Months 11 Natalie Hong, M.S. 2020-09-01
Long term follow up of patients with COVID 19 Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) General hospital of sestri levante China 2020-06-22 2020-10-31 ChiCTR2000036982 Phase Not Applicable Not yet recruiting 1 4 Months 250 Nicolini Antonello, Russo giuseppe 2020-09-04
Physiotherapy Practices for patients with COVID-19- A National Survey Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Sri Ramachandra Institute of Higher Education and Research India 2020-08-28 CTRI/2020/08/027393 Phase Not Applicable Not yet recruiting 1 250 Narasimman Swaminathan 2020-08-31
Evaluation of the Nextdoor KIND Challenge Coronavirus disease 19 infection, Psychiatric disorder KIND Challenge alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Swinburne University of Technology Brigham Young University, University of Manchester, University of Sydney Australia 2020-07-07 2020-12-31 NCT04398472, ND01 Phase Not Applicable Not yet recruiting 1 5 Months 9000 Michelle Lim 2020-09-02
Mi-CARE: Role of Midwifery Continuity of Care in Reducing Health Inequalities Coronavirus disease 19 infection Healthy volunteers accepted, Female, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Bournemouth University University Hospital Southampton NHS Foundation Trust UK 2020-10-01 2022-03-18 19/20/IRAS/CC, 262369, 45534, Mi-CARE, NCT04524286 Phase Not Applicable Not yet recruiting 1 17 Months 60 Charlotte Clayton, Suzy Wignall 2020-08-31
Anosmia and/or Ageusia and Early Corticosteroid Use Ageusia, Coronavirus disease 19 infection, Dysomia dexamethasone alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) ClinAmygate 2020-08-30 2020-12-15 NCT04528329, PR0013 Phase 4 Clinical Not yet recruiting 0 3 Months 300 2020-08-31
Clinical Trial Evaluating the Efficacy and Safety of Favipiravir in Moderate to Severe COVID-19 Patients Coronavirus disease 19 infection, Dyspnea, Respiratory distress syndrome favipiravir alone, supportive care alone RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dr Reddy's Laboratories Ltd Kuwait 2020-08-20 2021-01-31 CVD-04-CD-001, NCT04529499 Phase 3 Clinical Recruiting 2 5 Months 780 Carmela Fritz, Mohammad S. M. D. AlHumaidan, MBBS, Sagar Munjal, MD, MS, Salman Khalifa Al-Sabah, MD, Sarah Al Youha, Srinivas Shenoy, MD, Sulaiman Al Mazeedi 2020-08-31
GRAd-COV2 Vaccine Against COVID-19 Coronavirus disease 19 infection GRAd-COV2 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) ReiThera Srl Istituto Nazionale Per Le Malattie Infettive "Lazzaro Spallanzani", Ministero per l Universita e la Ricerca Scientifica e Tecnologica Italy 2020-08-10 2021-07-31 NCT04528641, RT-COV-2 Phase 1 Clinical Recruiting 4 11 Months 90 Antonella Folgori, CEO, Federica Mori, MGR, Simone Lanini, Simone Lanini, DR, Stefano Milleri, Medical Director 2020-09-01
COVID-pO2-RAAS: COVID-19 : Transcutaneous pO2 and pCO2 as Predictive Factors for Acute Respiratory Destress Syndrome in Patients Affected With SARS-Cov-2 Coronavirus disease 19 infection, Respiratory distress syndrome PeriFlux system 5000 (Perimed) alone, pulse oximetry alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Erasme Hospital Belgium 2020-10-04 2023-05-04 COVID-pO2-RAAS, NCT04524156, P2020/238 Phase Not Applicable Not yet recruiting 1 31 Months 100 Nora Bahhodh, Sofia Morra, MD 2020-08-31
OUR-Project: OUR Stress/Emotion Management for Black/African American Women With Hypertension Acute stress disorder, Coronavirus disease 19 infection, Hypertension Enhanced Co-Created Health Education InterventioN (eCo-CHIN) alone Healthy volunteers accepted, Female, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), African Ancestry Ohio State University US 2020-09-14 2022-01-30 2020B0182, NCT04526145, OUR-Project Phase Not Applicable Not yet recruiting 1 16 Months 30 Kathy D Wright, PhD, RN, Rashmeet Reen, PhD 2020-09-01
ICOPain: The influence of the Covid-19 pandemic on pain and pain related disability in chronic pain patients – an explorative study Coronavirus disease 19 infection, Pain Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitatsklinikum Essen Stiftung Universitätsmedizin Essen Germany 2020-04-20 20-9271-BO, DRKS00022395, ICOPain, U1111-1250-5064 Phase Not Applicable No longer recruiting 1 197 Ulrike Bingel 2020-09-02
MSC-based Therapy in COVID-19-associated Acute Respiratory Distress Syndrome Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure, Viral pneumonia mesenchymal stromal cell-based therapy alone, standard care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto D'Or de Pesquisa Brazil 2020-07-01 2020-10-31 NCT04525378, PCL02/2020 Phase 1 Clinical Recruiting 1 4 Months 20 Andre Gobatto, MD PHD, Bruno SF Souza, MD PHD 2020-09-01
A clinical trial of ASX-100 for the treatment of Coronavirus disease 19 infection associated Respiratory distress syndrome Coronavirus disease 19 infection, Respiratory distress syndrome ASX-100 alone Asalyxa Bio, University of Michigan Phase Not Applicable Planned 0 2020-08-28
COVID-19 Pandemic and Parents of Disabled Children Coronavirus disease 19 infection questionnaire alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Gaziosmanpasa Taksim Research and Education Hospital Turkey 2020-07-05 2020-09-15 105, NCT04525742 Phase Not Applicable Recruiting 1 2 Months 190 Berrin Huner, Speacilist, Berrin Huner, Specialist, Berrin Hüner, Ebru Yilmaz Yalcinkaya, Professor, Ebru Yilmaz Yalçınkaya, Professor, Evrim Karadağ Saygı, Professor, Nalan Çapan, Professor, Resa Aydin, Professor, Sibel Bektas, Professor, Özden Özyemisçi Taşkıran, Professor 2020-09-01
Assocation Between In-person Instruction and COVID-19 Risk Coronavirus disease 19 infection in-person instruction alone, online instruction alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Oslo and Akershus University College of Applied Sciences Norwegian Institute of Public Health Norway 2020-09-30 2020-12-31 172155, NCT04529421 Phase Not Applicable Not yet recruiting 1 3 Months 70000 Arnfinn Helleve, PhD, Atle Fretheim, PhD, Gro Jamtvedt, PhD 2020-09-04
Healthy Volunteer COVID-19 Antibody Testing Study Coronavirus disease 19 infection ARIA COVID-19 IgG/IgM Rapid Test (CTK Biotech, Inc) alone, enzyme-linked immunosorbent assay alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Royal Free Hospital NHS Foundation Trust UK 2020-09-01 2021-04-30 134035, NCT04529460 Phase Not Applicable Not yet recruiting 1 8 Months 200 Daniel Martin, MB ChB, Helder Filipe 2020-08-31
A phase I trial to evaluate MAN-19 to treat complications caused by COVID-19 Coronavirus disease 19 infection MAN-19 alone Q BioMed Inc Canadian Government, German Government 2021-02-28 Phase 1 Clinical Planned 0 2020-08-28
Study of the Safety and Efficacy of STI-5656 (Abivertinib Maleate) in Subjects Hospitalized Due to COVID-19 Coronavirus disease 19 infection abivertinib alone, standard of care alone Btk tyrosine kinase inhibitor, EGFR gene inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sorrento Therapeutics Inc US 2020-09-30 2021-05-31 BTK-COV-202BR, NCT04528667 Phase 2 Clinical Not yet recruiting 1 8 Months 400 Mike Royal, MD 2020-08-28
STAUNCH-19: Steroids and Unfractionated Heparin in Critically Ill Patients With Pneumonia From COVID-19 Infection Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia Variable regimens including Veracer , enoxaparin sodium biosimilar, Techdow , methylprednisolone (Pfizer) Low molecular weight heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Modena and Reggio Emilia Italy 2020-09-01 2021-07-30 NCT04528888, STAUNCH-19, STAUNCH-19-1.1-26-04-20 Phase 3 Clinical Not yet recruiting 2 10 Months 210 Massimo Girardis, PD, Massimo Girardis, PI, Stefano Busani 2020-09-02
Project Resurgence Communication Trial Coronavirus disease 19 infection communication by letter alone, mailed intervention letter alone University of Pennsylvania US 2020-06-15 2020-07-17 843220, NCT04418947 Phase Not Applicable Completed 1 1 Month 11120 Anne Cappola 2020-08-28
An observational study to evaluate the association between treatment with heparin and survival in patients with COVID-19 Coronavirus disease 19 infection heparin alone Guy's & St Thomas' Hospital NHS Trust, King's College London, National Institute for Health Research (NIHR) Spain Phase Not Applicable Status not specified 1 1734 2020-08-28
A case report to evaluate the efficacy of anakinra in patient with COVID-19 infection Coronavirus disease 19 infection anakinra alone Type I IL-1 receptor antagonist Male Fondazione IRCCS Ca' Granda-Ospedale Maggiore Policlinico Italy Phase Not Applicable Status not specified 1 1 2020-08-30
A phase I clinical trial of EPV-CoV-19 for potential prevention of COVID-19 Coronavirus disease 19 infection EPV-CoV19 alone EpiVax Inc, EpiVax Oncology Inc Phase 1 Clinical Planned 0 2020-08-27
TRACE ll Prospective: Outcome in patients undergoing postponed elective surgery during the COVID-19 pandemic Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Amsterdam UMC The Netherlands Organisation for Health Research and Development Netherlands 2020-09-01 2021-12-31 NL8841, TRACE ll Prospective Phase Not Applicable Not yet recruiting 1 16 Months Carin Wensing 2020-08-28
The efficacy of methylprednisolone mini pulse on the treatment of COVID-19 patients admitted to intensive care unit Coronavirus disease 19 infection Standard treatment alone, methylprednisolone alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ardabil University of Medical Sciences Iran 2020-07-10 IR.ARUMS.REC.1399.206, IRCT20170716035126N4 Phase 3 Clinical No longer recruiting 2 60 Afshin Habibzadeh, Dr. Masoud Entezari Asl, Yousef Mohammadi Kebar 2020-08-28
TRACE ll Retrospective: Outcome in patients undergoing (postponed) surgery during the COVID-19 pandemic Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Maastricht UMC+ Netherlands 2020-08-31 2020-12-31 NL8837, TRACE ll Retrospective Phase Not Applicable Recruiting 1 4 Months 14000 Carin Wensing 2020-08-28
A clinical trial of Digid Cantisense SARS-CoV-2 test for COVID-19 infection Coronavirus disease 19 infection Digid Cantisense SARS-CoV-2 test alone Mainz University Hospital Germany Phase Not Applicable Not yet recruiting 1 2020-08-28
Treatment and Prevention of Acute Lung Injury (ALI) in Patients With COVID-19 Infection Acute lung injury, Coronavirus disease 19 infection, Inflammatory disease, Viral pneumonia daxdilimab alone Leukocyte Ig like receptor A4 modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Viela Bio US 2020-08-28 2021-03-31 NCT04526912, VIB7734.P1.S2 Phase 1 Clinical Recruiting 1 7 Months 48 Daniel Falleroni, Gábor Illei, MD, PhD, MHS 2020-09-03
COVID-19 Survivorship Registry Coronavirus disease 19 infection, Pulmonary heart disease MRI alone, chest imaging alone, echocardiography alone, spirometry alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) NYU Langone Health US 2020-07-17 2023-08-31 20-00909, NCT04527315 Phase Not Applicable Recruiting 1 37 Months 350 Ashley Witzl, Ellen Hada, Rany Condos, MD 2020-08-31
Efficacy and feasibility of an audio-based mindfulness intervention in reducing anxiety, depression and stress among people with the risk of anxiety and depression during the coronavirus disease 2019 (COVID-19) pandemic in Thailand Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression audio-guided mindfulness practice program alone, psychoeducation alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Faculty of Medicine Siriraj Hospital, Mahidol University Thailand 2020-09-15 TCTR20200819003 Phase 2 Clinical Not yet recruiting 1 70 Natee Viravan 2020-08-29
LF-COVID: Lactoferrin for Prevention of COVID-19 in Health Care Workers Coronavirus disease 19 infection bovine lactoferrin alone, standard personal protection measure alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Universidad Peruana Cayetano Heredia Peru 2020-09-01 2021-11-01 LF-COVID, NCT04526821, SIDISI 202110 Phase 2 Clinical Not yet recruiting 2 14 Months 336 Carlos Medina, MD, Eddie Angles, MD, Fernando Mejia, MD, Msc, Jorge Florez, MD, Meylin Aphang, MD, Msc, Theresa J Ochoa, MD, PhD 2020-09-04
Detecting SARS-CoV-2 in Tears Coronavirus disease 19 infection IHC staining alone, RT-PCR alone, biological sampling alone, tear collection alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Minnesota US 2020-09-30 2021-04-30 NCT04526769, STUDY00009512 Phase Not Applicable Not yet recruiting 1 7 Months 30 Corey Miller, Hossein Nazari, MD 2020-08-28
Study of COVID-19 DNA Vaccine (AG-0302-COVID19) Coronavirus disease 19 infection AG-0302-COVID19 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) AnGes MG Inc Japan 2020-08-31 2021-09-30 AG0302-COVID19-JN-01, JapicCTI-205419, NCT04527081 Phase 1/Phase 2 Clinical Recruiting 1 13 Months 30 AnGes, Inc. Clinical Development 2020-09-04
ISARIC: Case Fatalities in Hospitalized COVID-19 Patients in the UK Coronavirus disease 19 infection University of Edinburgh ISARIC UK 2020-02-24 2020-08-02 ISARIC, ISARIC-COVID-CF, NCT04527458 Phase Not Applicable Completed 1 5 Months 70000 Annemarie B Docherty, Ewen M Harrison, Rachel H Mulholland 2020-08-28
An observational case report to determine the subacute thyroiditis associated with Covid-19 infection Coronavirus disease 19 infection hydroxychloroquine alone, prednisolone alone Female, European Ancestry Ankara City Hospital Bilkent Phase Not Applicable Status not specified 0 1 2020-08-27
A phase Ib/II, randomized, double-blind, placebo-controlled study to assess the safety and efficacy of alvelestat in adult patients hospitalized with moderate to severe COVID-19 respiratory disease not yet receiving mechanical ventilation Coronavirus disease 19 infection, Respiratory disease alvelestat alone, standard of care alone Leukocyte elastase inhibitor Mereo BioPharma Group Ltd US 2020-08-25 Phase 1/Phase 2 Clinical Recruiting 1 15 Dr. J. Michael Wells 2020-08-27
CHIP: COVID-19 Health Professional Impact Study Coronavirus disease 19 infection SARS-CoV-2 antibody test alone Healthy volunteers accepted The Royal Wolverhampton Hospitals NHS Trust The University Of Wolverhampton UK 2020-09-10 2020-12-31 2020COV112, CHIP, NCT04527432 Phase Not Applicable Not yet recruiting 1 3 Months 3000 Lorraine Jacques, Supratik Basu 2020-08-31
Effect of donkey milk on the new COVID-19 Coronavirus disease 19 infection candy intake alone, donkey milk intake alone, drug treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Kerman University of Medical Sciences Iran 2020-09-05 IR.KMU.REC.1399.321, IRCT20161108030776N3 Phase Not Applicable Not yet recruiting 1 110 Abbas Pardakhty, Haleh Tajadini, Haleh tajadini, Mohadese Kamali 2020-08-29
IveprofCovid19: Effectiveness and Safety of Ivermectin for the Prevention of Covid-19 Infection in Colombian Health Personnel Coronavirus disease 19 infection ivermectin alone Chloride channel modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Javeriana University Colombia 2020-09-07 2020-12-16 EPI1JAVECALI, IveprofCovid19, NCT04527211 Phase 3 Clinical Not yet recruiting 1 3 Months 550 Eduar D. Echeverri, Dr., Eduar d Echeverri, Dr., Julian Santaella, PhD 2020-08-28
Study to Evaluate the Efficacy and Safety of AstroStem-V in Treatment of COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia AstroStem-V alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Nature Cell Co. Ltd. 2020-12-01 2022-04-01 ASVP1N2A-US, NCT04527224 Phase 1/Phase 2 Clinical Not yet recruiting 0 16 Months 10 Hugh Lee, WonHo CHUN 2020-09-05
Extremely Premature Births During the Peak of the COVID-19 Pandemic: an International Study of the Active SafeBoosC III Departments Coronavirus disease 19 infection, Premature labor Newborn Infants (up to 5 months), Infants (6-23 months) Rigshospitalet, Denmark Denmark 2020-08-21 2020-09-13 NCT04527601, SAFEBOOSC COVID-19 ELGAN STUDY Phase Not Applicable Recruiting 1 500 Gitte Hahn, MD,PhD, Gorm Greisen, Gorm Greisen, MD, Prof, Marie Isabel Skov Rasmussen, MBBS 2020-09-03
The Effects of Filter During CPET on WOB and Aerosol Particle Concentrations Coronavirus disease 19 infection Vyair Vmax (Vyaire medical) alone, cardiopulmonary exercise testing alone, mask with in-line filter alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Rush University Medical Center Lundquist Institute US 2020-08-29 2020-12-31 CPET-001, NCT04526925 Phase Not Applicable Recruiting 1 4 Months 10 Jie Li, MS, Jie Li, PhD 2020-08-28
A clinical trial of UNI911for the treatment of Covid-19 Coronavirus disease 19 infection niclosamide (COVID-19), UNION therapeutics/ Institut Pasteur Korea alone S phase kinase associated protein 2 inhibitor UNION therapeutics Phase not specified Planned 0 2020-08-27
Study of Ensifentrine or Placebo Delivered Via pMDI in Hospitalized Patients With COVID-19 Coronavirus disease 19 infection ensifentrine alone, standard of care alone CFTR stimulator, PDE 3 inhibitor, PDE 4 inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Verona Pharma Inc Verona Pharma plc US 2020-08-28 2021-03-31 NCT04527471, RPL554-COV-201 Phase 2 Clinical Recruiting 1 7 Months 45 Verona Pharma Inc 2020-09-03
Heat Shock Protein Inhibitor- MPT-0B640 for COVID-19 Infection Coronavirus disease 19 infection MPT-0B64 alone Heat shock protein HSP90 alpha inhibitor, Heat shock protein HSP90 beta inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Joseah Biopharma Co Ltd 2020-12-31 2021-12-31 JO201901-02, NCT04526717 Phase 1 Clinical Not yet recruiting 0 12 Months 15 Ethan Seah, Haein Kim, JiHye Choe 2020-08-29
A human trial of SAR-CoV-2 vaccine (recombinant protein, COVID-19)for the prevention of COVID-19 Coronavirus disease 19 infection SAR-CoV-2 vaccine (recombinant protein, COVID-19), Sichuan University/Zhejiang Teruisi Pharmaceutical/Chengdu Institute of Biological Products alone Sichuan University Phase Not Applicable Planned 0 2020-08-27
COLCOVIDBD: Colchicine in Moderate Symptomatic COVID-19 Patients Coronavirus disease 19 infection colchicine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dhaka medical college Bangladesh 2020-07-14 2020-12-31 COLCOVIDBD, NCT04527562, U1111-1255-3541 Phase 2 Clinical Recruiting 1 5 Months 300 Motlabur Rahman, MBBS, FCPS,FACP, Motlabur Rahman, MBBS,FCPS,FACP, Mujibur Rahman, MBBS,MD,FCPS, Ponkaj Datta, MBBS, FCPS, Ponkaj Datta, MBBS,FCPS 2020-08-31
A phase II trial to evaluate BGE-175 in hospitalized COVID-19 patients Coronavirus disease 19 infection BGE-175 alone PGD2 antagonist BioAge Labs Inc Phase 2 Clinical Planned 0 2020-09-02
CoVIHDis: Differences in Immune Response Among HIV-1-infected Individuals With Previous or Current COVID-19 Coronavirus disease 19 infection, HIV-1 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Asociacion para el Estudio de las Enfermedades Infecciosas Spain 2020-09-01 2021-09-30 CoVIHDis, EC 273/20, NCT04526977 Phase Not Applicable Not yet recruiting 1 13 Months 90 Alejandro Vallejo, PhD, Jose L Casado, PhD 2020-08-29
A Patient Perspective Survey on Masking or De-Masking the Medical Staff amid COVID-19 Pandemic Coronavirus disease 19 infection Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Maroondah hospital Box Hill Hospital Australia 2020-03-23 ACTRN12620000808943, U1111-1256-1499 Phase Not Applicable Recruiting 4 500 Dr Aihua Wu 2020-08-31
LIBERTY: Controlled clinical trial of hydroxychloroquine in the treatment of adult patients with Covid-19 infection in a primary care setting Coronavirus disease 19 infection Oxiklorin alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Porin kaupunki Finland 2020-07-16 2020-002038-33, LIBERTY, LIBERTY Phase 2 Clinical Recruiting 1 600 CRST Oy 2020-09-01
An Open, Non-comparative Study of the Efficacy and Safety of Aprotinin in Patients Hospitalized With COVID-19 Coronavirus disease 19 infection, Lung injury, Viral pneumonia Gordox alone, standard of care alone, Gordox plus favipiravir RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Aviron Pharma LLC Russian Federation 2020-06-11 2020-08-31 COVID-APR-01, NCT04527133 Phase 2 Clinical No longer recruiting 1 2 Months 30 Elena Simakina, MD 2020-08-29
Clinical Course and Treatment of COVID-19 Inpatients in Hospital Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Wissenschaftliches Institut Bethanien e.V. Germany 2020-08-01 2021-08-31 NCT04527497, WI_20-1294 Phase Not Applicable Recruiting 1 13 Months 50 Anja Pietzke-Calcagnile, Dr., Marcel Treml, Dr., Simon Herkenrath, Winfried Randerath, Prof. Dr. 2020-08-29
Effect of traditional medicine protocol included Astraglus gossypinus with Ferula assa capsule on improvement of COVID-19 outpatients symptoms Coronavirus disease 19 infection standard Corona treatment alone, Astragalus gossypinus syrup plus Ferula assafoetida syrup Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kerman University of Medical Sciences Iran 2020-08-10 IR.KMU.REC.1399.275, IRCT20101219005416N3 Phase Not Applicable Recruiting 1 120 Abas Pardakhti, Haleh Tajadini 2020-08-28
Effect of a Brief Mood Training Program on Anxiety and Depression Arising from COVID-19-Related Stress Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression positive mood training alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) UNSW Sydney National Health and Medical Research Council Australia 2020-09-30 2021-01-29 ACTRN12620000811909p Phase Not Applicable Not yet recruiting 9 4 Months 240 Prof Richard Bryant 2020-08-31
A phase I/II clinical trial of injector type GX-19 covid vaccine Coronavirus disease 19 infection GX-19 alone Gangnam Severance Hospital, Genexine Co Ltd, Severance Hospital South Korea Phase 1/Phase 2 Clinical Planned 2 2020-08-31
BRAINSTEM-COV: Brainstem Dysfunction in COVID-19 Critically Ill Patients: a Prospective, Observational Study Brainstem disease, Coronavirus disease 19 infection electrocardiography alone, electroencephalography alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-08-31 2021-05-31 2020-A01559-30, APHP200644, BRAINSTEM-COV, NCT04527198 Phase Not Applicable Not yet recruiting 2 9 Months 40 Adèle BELLINO, Bertrand HERMANN, MD, PhD, Bertrand HERMANN, MD,PhD, Sarah BENGHANEM, MD 2020-08-29
PICOV: Influence of Prior Infection With COVID-19 on Occurrence of Influenza-like Illness or Acute Respiratory Infection Coronavirus disease 19 infection, Influenza virus infection, Respiratory syncytial virus infection, Respiratory tract infection multiplex assay alone, qRT-PCR test alone, serology testing alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sciensano Institute of Tropical Medicine, Belgium, Mensura EDPB, Universite Libre de Bruxelles Belgium 2020-09-01 2021-05-30 NCT04527614, PICOV, PICOV2021 Phase Not Applicable Not yet recruiting 1 8 Months 2000 Maria Gpossens 2020-08-28
MSCCOVIDP: Mesenchymal stromal cell (MSC) therapy for COVID-19 pneumonia Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia bone-marrow derived mesenchymal stromal cells (MSC) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Royal Perth Hospital Australia 2020-05-05 2020-12-30 ACTRN12620000840987, CT-2020-CTN-01580-1 v1, MSCCOVIDP, RGS0000003982, U1111-1254-9427 Phase 1 Clinical Recruiting 2 7 Months 10 A/Prof Marian Sturm, Dr Ben Carnley 2020-09-02
A Phase I/II, randomized, placebo-controlled, multicenter study to evaluate the safety and immunogenicity of COVID-19 Vaccine in Healthy Adults Coronavirus disease 19 infection RBD SARS-CoV-2 HBsAg VLP vaccine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) ACCELAGEN PTY LTD, Serum Institute of India Ltd Australia 2020-08-17 2020-11-30 ACTRN12620000817943p Phase 1/Phase 2 Clinical Not yet recruiting 2 3 Months 280 A/Prof Paul Griffin, Mr Greg Plunkett 2020-08-31
A post-registration, randomized, double-blind, placebo-controlled multicenter clinical study of the efficacy, immunogenicity and safety of the Sputnik V vaccine Coronavirus disease 19 infection Sputnik V alone COVID19 Spike glycoprotein modulator Gamalei Institute of Epidemiology and Microbiology, Russian Direct Investment Fund Russian Federation Phase 4 Clinical Not yet recruiting 1 40000 2020-08-27
COFIT registry: Registry of Covid 19 survivors for Fitness, exercise impairment and exercise Training Coronavirus disease 19 infection Maxima Medisch Centrum Veldhoven Netherlands 2020-08-14 2022-08-14 COFIT registry, NL8836 Phase Not Applicable Recruiting 1 24 Months 200 Martijn van Hooff 2020-08-28
ICU-VR after COVID-19: Intensive Care Unit specific Virtual Reality (ICU-VR) to improve psychological impairments in survivors of COVID-19: a multicenter, randomized, controlled trial Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder Intensive Care Unit Specific Virtual Reality therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Erasmus University Medical Center Rotterdam BeterKeten, Franciscus Gasthuis & Vlietland, Stichting Coolsingel 2020-06-29 2021-12-31 ICU-VR after COVID-19, NL8835 Phase Not Applicable Recruiting 0 18 Months 80 Johan Vlake 2020-08-28
C-SMART (Arm 3): COVID-19 Prevention and Treatment in Cancer: Arm 3: treatment among cancer patients with moderate COVID-19 infection Coronavirus disease 19 infection IFN-alpha alone, lenzilumab alone, selinexor alone Exportin 1 inhibitor, GM-CSF ligand inhibitor, Immunoglobulin G1 modulator, Immunoglobulin kappa modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Peter MacCallum Cancer Centre Australian Government Australia 2020-09-01 2021-12-01 ACTRN12620000841976, ANZCTR380423, C-SMART (Arm 3), HREC/65954/PMCC, U1111-1256-8488 Phase 3 Clinical Not yet recruiting 5 15 Months 126 Dr Michelle Yong, Mr Ronan Burder, Prof Monica Slavin 2020-09-01
Crit-Cov-U: Prospective validation of a proteomic urine test for early and accurate prognosis of critical course complications in patients with SARS-CoV-2 infection Coronavirus disease 19 infection proteomic urine test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hannover Medical School Deutsche Forschungsgemeinschaft (DFG), German Federal Ministry of Education and Research Austria, Germany 2020-08-01 Crit-Cov-U, DRKS00022495, EK-BR-88/20-1 Phase Not Applicable Recruiting 2 1000 Heiko von der Leyen, Joachim Beige 2020-08-28
Prediction Models for Diagnosis and Prognosis of Severe COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure, Shock, Viral pneumonia artificial intelligence model alone, computed tomography alone Second Affiliated Hospital ZheJiang University College of Medicine China 2020-02-20 2020-08-20 2020-12020001231, NCT04525287 Phase Not Applicable Recruiting 1 6 Months 1000 Luopei Wei, Minming Zhang, PHD 2020-08-28
Methylene Blue in COVID-19 Coronavirus disease 19 infection, Respiratory failure corticosteroid therapy alone, Metiblo, Oterop company plus lopinavir + ritonavir HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shiraz University of Medical Sciences Iran 2020-08-15 IR.SUMS.REC.1399.016, IRCT20090701002113N2 Phase 3 Clinical Recruiting 2 260 Jamshid Roozbeh, Siavash Gholami, Yunos Ghasemi 2020-08-29
Wide Scale Monitoring for Acute Respiratory Infection Using a Mobile-based Study Platform Coronavirus disease 19 infection, Influenza virus infection, Respiratory tract infection mobile-based study platform app (Google Inc) alone, wide scale monitoring alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Boston Children's Hospital Google Inc US 2020-09-30 2021-09-30 IRB-P00036213, NCT04525118 Phase Not Applicable Not yet recruiting 1 12 Months 100000 Emily Cohn, MPH, John Brownstein, Kara Sewalk, MPH 2020-08-29
A Phase I Study of the EmitBio RD19 Device to Prevent SARS-CoV-2 and COVID-19 Coronavirus disease 19 infection EmitBio RD19 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) KNOW Bio LLC M3-Wake Research Associates Carolina Phase I Clinical Trial Unit, TAB Clinical US 2020-08-31 2020-10-01 NCT04525976, RD19-01-3Q20 Phase Not Applicable Not yet recruiting 1 1 Month 25 Aubrey Farray, John G McNeil, MD MPH PHD, Lisa Cohen, DO, Lisa Eckert, PA, Lynn A Bagylos, MSN 2020-08-28
Hand Sanitizer Effects on the Skin Barrier Atopic dermatitis, Coronavirus disease 19 infection hand sanitizer alone, hand washing alone, skin tape strip test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) National Jewish Health US 2020-08-18 2021-08-20 3030005053, HS 0720, NCT04525521 Phase Not Applicable Recruiting 1 12 Months 40 Jessica Hui, Jessica Hui, MD 2020-08-28
COVIDSTORM: Use of Tocilizumab in the inflammatory phase of COVID-19 / new coronavirus disease Coronavirus disease 19 infection tocilizumab (intravenous), Roche/Chugai alone IL-6 receptor antagonist, IL-6 receptor modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Turku University Hospital Finland 2020-06-17 2020-002039-31, COVIDSTORM, covidstorm Phase 3 Clinical Recruiting 1 90 2020-08-28
Rapid Screening Test for COVID-19 Antibodies in Healthcare Workers Coronavirus disease 19 infection AAZ rapid test alone, ELISA test alone, blood sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Groupe d'Etude sur le Risque d'Exposition des Soignants aux Agents Infectieux France 2020-04-25 2020-10-25 GERES20200409, ID RCB 2020-A01031-38, NCT04525417 Phase Not Applicable Recruiting 1 6 Months 100 Charlotte Charpentier, MD, Elisabeth Bouvet, MD, Gerard Pellissier, PhD 2020-08-28
ThalaCoV: Frequency of COVID-19 Antibodies in Patients With Hereditary Hematological Diseases Coronavirus disease 19 infection, Diamond Blackfan anemia, Hematological disease, Sickle cell anemia, Thalassemia intermedia, Thalassemia major SARS-CoV-2 S1/S2 IgG analysis alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Milano-Bicocca Italy 2020-07-14 2020-10-30 NCT04526405, THALACOV, ThalaCoV Phase Not Applicable Recruiting 6 3 Months 81 Alberto Piperno, Prof, Sara Pelucchi, Dr.ssa 2020-08-29
PrEP-Co: SARS-CoV-2 serology in HIV PrEP users during the COVID-19 pandemic Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Klinikum rechts der Isar der Technischen Universitaet Muenchen Germany 2020-05-18 292/20 S, DRKS00022403, PrEP-Co Phase Not Applicable Recruiting 0 300 Christoph Spinner 2020-09-03
Morphological Abnormalities of the Olfactory Bulb on MRI and Olfactometry in Anosmic Versus Normosmic COVID-19 Patients Coronavirus disease 19 infection, Olfaction disorder anterior rhinoscopy alone, brain MRI alone, nasofibroscopy alone, olfactometry test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopital Foch Raymond Poincare University Hospital France 2020-09-06 2021-09-06 2020-0057, NCT04526054 Phase Not Applicable Not yet recruiting 2 12 Months 30 Elisabeth Hulier-Ammar, Dr, Jerome Lechien, Dr, Robert-Yves Carlier, Pr, Stephane Hans, Pr 2020-08-28
CHDR2029: In vitro characterization of the immune response of recovered COVID-19 patients and healthy controls to SARS-CoV-2 Coronavirus disease 19 infection blood sampling alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) ISA Pharmaceuticals BV 2020-08-10 2020-09-30 CHDR2029, NL74814.058.20, NL8821 Phase Not Applicable Not yet recruiting 0 1 Month 14 I.M.C. de Visser-Kamerling 2020-08-28
ALCOVID: Assessment of Long-term Impact Post COVID-19 for Patients and Health Care Professionals of the European Hospital Coronavirus disease 19 infection serology test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hôpital Européen Marseille France 2020-08-17 2022-10-31 2020- A01647-32, ALCOVID, NCT04525911 Phase Not Applicable Not yet recruiting 1 26 Months 258 Hervé PEGLIASCO, Myriam BENNANI 2020-08-28
Preparations of Dutch Emergency Departments for the SARS-COV-2 outbreak Coronavirus disease 19 infection Zuyderland Medical Center, Heerlen Netherlands 2020-07-29 2020-10-01 NL8818, Z2020149 Phase Not Applicable Recruiting 1 2 Months 84 Rory O'Connor 2020-08-28
The Effect of COVID-19 on Patient Outcomes Among Operated Patients Coronavirus disease 19 infection surgery alone Karolinska Institutet Sweden 2020-03-01 2020-12-31 COVIDKIRURGI, NCT04525716 Phase Not Applicable Recruiting 1 10 Months 2000 Andreas Älgå, Andreas Älgå, MD, PhD, Gabriel Sandblom, MD, PhD 2020-08-31
Endothelial Function and COVID-19 Coronavirus disease 19 infection EndoPat system, Itamar alone, Peripheral arterial tonometry alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Clinico San Carlos Mayo Clinic, Minnesota US, Spain 2020-06-03 2020-09-30 20/451, NCT04525443 Phase Not Applicable Recruiting 2 3 Months 100 Alejandro Travieso, MD, Eduardo Martinez, MD, Hernan Mejia-Renteria, M.D, Hernan Mejia-Renteria, MD, Hernán Mejía-Rentería, MD, Javier Escaned, MD, PhD 2020-08-29
Lower morbidity and mortality in COVID-19 patients admitted in a dedicated COVID Hospital of Odisha - a radiological perspective Coronavirus disease 19 infection Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kalinga Institute of Medical Sciences India 2020-08-20 CTRI/2020/08/027247 Phase Not Applicable Not yet recruiting 1 1500 Dr Roopak Dubey, Dr col Kamal Kumar sen 2020-08-27
VitCov: High Dose Vitamin-D Substitution in Patients With COVID-19: a Randomized, Controlled, Multicenter Study Coronavirus disease 19 infection, Vitamin D deficiency standard treatment alone, vitamin D3 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kantonsspital Baselland Switzerland 2020-09-01 2021-06-30 2020-01401, NCT04525820, VitCov Phase Not Applicable Not yet recruiting 3 10 Months 80 Fabienne Jaun, BScN, Jörg D Leuppi, Professor, Michael Brändle, Professor, Philipp Schütz, Professor, Prof. Dr. Jörg Leuppi 2020-08-27
Role of Tocilizumab in COVID-19 Pneumonia patients Coronavirus disease 19 infection, Viral pneumonia tocilizumab alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gujarat Cancer Society Medical college hospital and research centre India 2020-09-01 CTRI/2020/08/027246 Phase Not Applicable Not yet recruiting 1 40 Dr Jay Shah, Dr Shaila Shah 2020-08-31
MOIST: Multi-Organ Imaging With Serial Testing in COVID-19 Infected Patients Coronavirus disease 19 infection, Fatty liver disease, Heart injury, Inflammatory disease, Liver injury blood test alone, cognitive testing alone, high-sensitivity troponin testing alone, multi-organ MRI scan alone, olfaction testing alone, spiromety alone, walk test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Alberta Canadian VIGOUR Centre Canada 2020-09-01 2021-09-01 MOIST, NCT04525404, PRO00102389 Phase Not Applicable Not yet recruiting 1 12 Months 228 Ian Paterson, MD, Karin Kushniruk, RN, PhD 2020-08-31
Behavioral and emotional difficulties of school going children during COVID times Coronavirus disease 19 infection Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) Lokopriya Gopinath Bordoloi Regional Institute of Mental Health India 2020-08-29 CTRI/2020/08/027244 Phase Not Applicable Not yet recruiting 1 3500 Dr Subhashish Nath 2020-08-26
International phase II/III trial of GRAd-COV2 against covid-19 infection Coronavirus disease 19 infection GRAd-COV2 alone COVID19 Spike glycoprotein modulator ReiThera Srl Phase 2/Phase 3 Clinical Planned 0 2020-08-26
Identifying the factors that alters the recovery time of the COVID-19 patients Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sri Ramachandra Hospital, Chennai India 2020-09-11 CTRI/2020/08/027243 Phase Not Applicable Not yet recruiting 1 500 T Gayathri 2020-08-27
Study of Radiotherapy practice during Corona Pandemic Cancer, Coronavirus disease 19 infection radiotherapy alone Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tata Memorial Hospital India 2020-08-28 CTRI/2020/08/027226 Phase Not Applicable Recruiting 1 2500 Jai Prakash Agarwal 2020-08-27
COVID-19 prevalence during pregnancy and pregnancy outcomes in low resource settings Coronavirus disease 19 infection blood sampling alone Female, Young Adults (18-44 yrs) Eunice Kennedy Shriver National Institute of Child Health & Human Development Global Network for Women's and Children's Health Research India, Kenya, Congo, The Democratic Republic of the, Zambia, Bangladesh, Pakistan 2020-08-01 CTRI/2020/08/027218 Phase Not Applicable Not yet recruiting 7 16000 Dr Archana Patel, Dr Shivaprasad S Goudar 2020-08-28
SCION: A backdated comparison of patients operated before the COVID-19 pandemic versus those operated during the COVID_19 pandemic Coronavirus disease 19 infection, Infectious disease cancer surgery alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tata Memorial Centre India 2020-08-19 CTRI/2020/08/027210, SCION Phase Not Applicable Not yet recruiting 1 3000 Dr Gouri Pantvaidya 2020-08-27
POMPCO: A survey to collect vital parameters and symptoms of participants at risk of COVID19 Coronavirus disease 19 infection wearable health device alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) INNOWEAR TECHNOLOGIES PRIVATE LIMITED India 2020-08-26 CTRI/2020/08/027323, POMPCO Phase Not Applicable Not yet recruiting 2 100 Dr Manoj Yadav, Megha Patel 2020-08-27
A study regarding knowledge, attitude and practice about immunity boosting measures for prevention of COVID-19 infection among healthcare workers at tertiary care hospital Coronavirus disease 19 infection Immunity Boosting measures for self-care alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Bhaikaka University India 2020-09-15 CTRI/2020/08/027359 Phase Not Applicable Not yet recruiting 1 300 Dr Manisha Gohel 2020-08-27
To assess the clinical efficacy of Ayurvedic interventions in managing asymptomatic to mild cases of COVID-19 Coronavirus disease 19 infection Broncho-T Granules alone, Variable regimens including Agasthya Haritaki , Anu taila , Ayush-64 Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shri Dhanwantry Ayurvedic college and hospital India 2020-08-25 CTRI/2020/08/027346 Phase 2/Phase 3 Clinical Not yet recruiting 1 60 Shikha Chaudhary 2020-08-28
To Evaluate Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of DWRX-2003 Against COVID-19 Coronavirus disease 19 infection repositioned niclosamide (refractory lung disease/COVID-19), Daewoong Pharmaceutical/Institut Pasteur Korea alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Daewoong Pharmaceutical Co Ltd 2020-08-31 2020-12-31 DWJ1516101_INDIA, NCT04524052 Phase 1 Clinical Not yet recruiting 0 4 Months 32 2020-08-27
mCCP: Safety of convalescent plasma (CVP) drawn from mild symptomatic COVID-19 patients Coronavirus disease 19 infection Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Medical Sciences China 2020-08-21 CTRI/2020/08/027285, mCCP Phase Not Applicable Recruiting 1 100 Diptiranjan Rout 2020-08-28
LLLT Treatment of Lung Inflammation in COVID-19 Coronavirus disease 19 infection, Lung inflammation, Respiratory distress syndrome, Viral pneumonia Non-invasive low-level laser therapy treatment alone, Standard care therapy alone, UltraSlim red/IR LED device alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ward Photonics LLC US 2020-07-26 2021-01-31 CP19-02, NCT04524715 Phase Not Applicable Recruiting 2 6 Months 64 Gina M Brewer, Patty J Lee, MD, Randal Horsley, DC, Randal Horsley, DO, Rober H Burke, MD 2020-08-28
A study to evaluate the efficacy and safety of Aceinavir combined with supportive Standard of Care (SoC) in hospitalized patients with moderate coronavirus disease (COVID-19) Coronavirus disease 19 infection Aceinavir alone, Standard of Care (SoC) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dyuthi Biosciences Private Limited India 2020-08-28 CTRI/2020/08/027284, TG/PRO/CLI/035 Version 2.0 Phase 2 Clinical Not yet recruiting 1 44 Dr Shashank Acharya, Dr Sruthi Nambiar, Dr Vishal Rao 2020-08-28
UNC CCP RCT: COVID-19 Antibody Plasma Research Study in Hospitalized Patients Coronavirus disease 19 infection, Gastrointestinal disease, Respiratory disease convalescent COVID-19 plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of North Carolina US 2020-08-17 2021-05-31 20-1544, IGHID 12021, NCT04524507, UNC CCP RCT Phase 2 Clinical Recruiting 1 9 Months 56 Brian Gurney, ACNP, FNP, David M Margolis, MD, David van Duin, MD, PhD, JoAnn Kuruc, RN, MSN, Luther A Bartelt, MD 2020-08-28
A clinical trial to evaluate the medicinal efficacy and safety of ayurvedic kit in COVID-19 positive patients Coronavirus disease 19 infection Ayur Raksha capsules plus Ayur Raksha choorna Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) M/S AYURASHRAMA PHARMACEUTICALS India 2020-08-24 CTRI/2020/08/027283 Phase 2/Phase 3 Clinical Not yet recruiting 1 30 Dr BHAVYA DARSHINI M, Dr C R JAYANTHI, Dr VISHWA SANTHOSHA BHARATHI 2020-08-28
Clinical Trial of Ivermectin Plus Doxycycline for the Treatment of Confirmed COVID-19 Infection Coronavirus disease 19 infection antibiotic therapy alone, antihistamine therapy alone, drug therapy alone, oxygen therapy alone, vitamin intake alone, Variable regimens including doxycycline (Popular pharmaceutical limited) , ivermectin (Popular pharmaceutical limited) , low-molecular weight heparin , paracetamol Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dhaka medical college Bangladesh 2020-06-01 2020-08-30 ERC-DMC/ECC/2020/117, NCT04523831 Phase 3 Clinical Recruiting 1 2 Months 400 Mahmud Reaz, FCPS, Mahmud Reaz, FCPS, MD, Mahmud Reaz, FCPS. MD, Rahman Md Mujibur, FCPS 2020-08-28
Prophylactic Ivermectin in COVID-19 Contacts Coronavirus disease 19 infection ivermectin alone Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Government Institute of Medical Sciences, Greater Noida India 2020-08-31 CTRI/2020/08/027282 Phase 3 Clinical Not yet recruiting 1 180 Dr Hariom Kumar Solanki, Dr Rambha Pathak, Dr Saurabh Srivastava 2020-08-26
SPARTACOS-19 trial: Re-purposing of Anti HCV drugs for the treatment of COVID-19 disease Coronavirus disease 19 infection Daclatasvir/ Sofosbuvir alone, sofosbuvir + ledipasvir (fixed-combination/oral, HCV/HBV), Gilead alone Hepatitis C virus NS5B polymerase inhibitor, Hepatitis C virus protein NS5A inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Pt. B.D. Sharma PGIMS India 2020-08-31 CTRI/2020/08/027345, SPARTACOS-19 trial Phase 3 Clinical Not yet recruiting 1 175 Dhruva Chaudhry 2020-08-28
Ivermectin as a possible treatment for COVID-19 Coronavirus disease 19 infection ivermectin alone Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences Patna India 2020-08-28 CTRI/2020/08/027225 Phase 2 Clinical Not yet recruiting 1 90 Ravi Kirti 2020-08-27
Assessing the fear and worries associated with COVID-19 in out-patient population of a hospital Anxiety disorder, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Gujarat Cancer Society Medical college hospital and research centre India 2020-08-31 CTRI/2020/08/027281 Phase Not Applicable Not yet recruiting 1 250 Parth Shah 2020-08-28
To observe the effect of Ayurvedic medicine (Ashwagandha and Shunti) for the treatment of COVID-19 Coronavirus disease 19 infection Ashwagandha tablet plus Shunti Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Central Council for Research in Ayurvedic Sciences India 2020-08-25 CTRI/2020/08/027224 Phase 2/Phase 3 Clinical Not yet recruiting 1 60 Dr Harbans Singh, Dr Sumit Shrivastva 2020-08-28
The study of occurrence, distribution and control measures of COVID-19 among police personnel during pandemic in Pune city, Maharashtra Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) B.J.Medical College and Civil Hospital India 2020-08-20 CTRI/2020/08/027275 Phase Not Applicable Not yet recruiting 1 200 Dr Ganesh Jagdale, Dr Malangori A Parande 2020-08-28
CARDY-COVID: Cardiac Dysfunction in Critically Ill Patients Infected With COVID-19 Coronavirus disease 19 infection, Heart disease Echocardiography alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sahlgrenska University Hospital Sweden 2020-04-20 2020-09-30 CARDY-COVID, CARDY-COVID, NCT04524234 Phase Not Applicable Recruiting 3 5 Months 100 Jacob Holmqvist, MD, Jonatan Oras, MD, PhD 2020-08-26
Unani formulations for prevention of COVID-19 infection Coronavirus disease 19 infection Infuza alone, Kulzam alone, Infuza plus Kulzam Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hamdard Laboratories India 2020-08-24 CTRI/2020/08/027222 Phase 2 Clinical Not yet recruiting 1 200 Dr Kailash Chandra, Dr Mridu Dudeja, Dr Naushad Rana, Mr Ayan Kumar Das 2020-08-28
A CBT-based Mobile Intervention as First Line Treatment for Adolescent Depression During COVID-19 Anxiety disorder, Coronavirus disease 19 infection, Depression Limbix Spark digital mobile application (Limbix Health, Inc) alone, cognitive behavioral therapy alone Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs) Limbix Health Inc US 2020-07-20 2020-12-31 LIMBIX SPARK 02, NCT04524598 Phase Not Applicable Recruiting 1 5 Months 410 Aarthi Padmanabhan, PhD, Aarthi Padmanabhan, Phd, Jessica Lake, PhD, Marisa Cruz, MD 2020-08-28
Study to assess the usefulness, effectiveness and feasibility for future use of the consultations done using telephone/whatsapp in rheumatic diseases during CoVID-19 pandemic Coronavirus disease 19 infection, Musculoskeletal disease Tele-consultation alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences India 2020-09-01 CTRI/2020/08/027324 Phase Not Applicable Not yet recruiting 1 5000 Ranjan Gupta 2020-08-28
Study of Descartes-30 in Acute Respiratory Distress Syndrome Coronavirus disease 19 infection, Respiratory distress syndrome Descartes-30 alone Deoxyribonuclease stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cartesian Therapeutics US 2020-09-15 2022-09-25 DC30-1A, NCT04524962 Phase 1/Phase 2 Clinical Not yet recruiting 2 24 Months 30 Adam S Chowdhury, MD, MBA, Bruce D Levy, MD, Ryan Kennedy, MD 2020-09-05
Oral Camostat Compared With Standard Supportive Care in Mild COVID-19 Patients Coronavirus disease 19 infection Standard of care treatment alone, camostat mesylate alone Serine protease inhibitor, Transmembrane serine protease 2 inhibitor, Trypsin inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Stanford University US 2020-08-31 2021-04-30 56029, COPS-2002, NCT04524663 Phase 2 Clinical Not yet recruiting 1 8 Months 120 Julie Parsonnet, MD 2020-08-26
Prevalence and Outcomes of Olfactory and Gustatory Dysfunctions in Patients With COVID-19 Coronavirus disease 19 infection, Dysgeusia, Dysomia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ain Shams University Egypt 2020-07-11 2020-11-30 FMASUP46A/2020, NCT04524754 Phase Not Applicable Recruiting 1 4 Months 218 Fatma S Ebeid, MD, Mohamed Shehata Taha, ethical committee 2020-08-29
How does the COVID-19 quarantine affect physical activity levels? Coronavirus disease 19 infection physical activity alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Jobu hospital for respiratory diseases Japan 2020-09-01 UMIN000041526 Phase Not Applicable Not yet recruiting 1 400 Keita Takagawa 2020-08-27
COVID19-OR (SARS-CoV-2): Observation, Risk And Recovery Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Western Sussex Hospitals NHS Trust UK 2020-05-05 2022-05-08 20/YH/0157, COVID19-OR (SARS-CoV-2), NCT04524520 Phase Not Applicable Recruiting 1 24 Months 30 Dr Christina Koulouglioti, Dr Luke Hodgson, Dr Luke hodgson 2020-08-27
The effect of Atorvastatin therapy in COVID-19 Coronavirus disease 19 infection Variable regimens including atorvastatin , hydroxychloroquine , lopinavir + ritonavir HIV protease inhibitor, HMG CoA reductase inhibitor North Khorasan University of Medical Sciences Iran 2020-08-20 IR.NKUMS.REC.1399.035, IRCT20190831044653N5 Phase 2 Clinical Recruiting 1 160 Dr. Majid Ghafoori, Majid Ghafoori, Maryam Rameshrad, dr. seyed Kaveh Hojat 2020-08-27
Relation between HLA typing and ABO Blood group to infection by novel Wuhan Corona virus Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Christian Medical College, Vellore, India India 2020-08-25 12752, CTRI/2020/08/027194 Phase Not Applicable Not yet recruiting 1 80 Snehil Kumar 2020-08-27
Impact of COVID -19 situation on people staying and discharged from a psychiatric rehabilitation centre Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kasturba Medical College, Manipal India 2020-08-31 CTRI/2020/08/027193 Phase Not Applicable Not yet recruiting 1 54 Rajeshkrishna Bhandary P 2020-08-27
To assess the impact of COVID-19 pandemic on the delivery of radiation therapy in delhi national capital region, india Cancer, Coronavirus disease 19 infection Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Max Super Speciality Hospital India 2020-08-22 CTRI/2020/08/027192 Phase Not Applicable Not yet recruiting 3 500 Dr Rashi Agrawal 2020-08-27
Effect of ifiltration of dexamethasone as primary emergency management in patients with symptomatic apical periodontitis during Coronavirus Disease 2019 outbreak Coronavirus disease 19 infection, Pain dexamethasone plus ligocaine Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Pacific Dental College and hospital India 2020-08-24 CTRI/2020/08/027191 Phase 2 Clinical Not yet recruiting 1 42 Dr Afzal Ali 2020-08-27
Response time of motorlance in COVID-19 pandemic Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Khon Kaen University Thailand 2020-08-20 TCTR20200820006 Phase Not Applicable Recruiting 1 871 Korakot Apiratwarakul 2020-08-27
Role of chest CT scan in covid19 patients: A study in a dedicated covid hospital of odisha Coronavirus disease 19 infection Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) KIIT University India 2020-08-20 CTRI/2020/08/027189 Phase Not Applicable Not yet recruiting 1 1600 Sangram Panda 2020-08-27
The effect of Ayurvedic intervention (Ayurveda Raksha Kit) as a preventive measure in the Pandemic of COVID-19 - A community based study Coronavirus disease 19 infection Ayurvrda Raksha Kit alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Council for Research in Ayurvedic Sciences India 2020-08-28 CTRI/2020/08/027316 Phase 3 Clinical Not yet recruiting 20 Dr Alok Shrivastav, Dr Amin Hetalben, Dr Deepa Sharma, Dr Dipsunder Sahu, Dr EmySSurendram, Dr Gopesh Kumar, Dr Govind Reddy, Dr Jai Venkata Saiprasad, Dr K Anumol, Dr Kuldeep, Dr Laxman Bhurke, Dr PL Bharti, Dr Parvathy G Nair, Dr Rinky Thakur, Dr S Asha, Dr SK Vedi, Dr Seema jain, Dr Shriprakash, Dr Sunita mata, Dr Susmita P Otta, Dr Vineeta Kumari Negi 2020-08-27
Assessment of anxiety related to excessive internate search regarding covid-19 pandemic in medical students and para-medical staff Anxiety disorder, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Gujarat Cancer Society Medical college hospital and research centre India 2020-08-26 CTRI/2020/08/027301 Phase Not Applicable Not yet recruiting 1 200 Krishna Dave 2020-08-27
The effect of nebulizing peppermint extract and rose extract on percentage of blood oxygen saturation in patients with COVID-19 Coronavirus disease 19 infection peppermint extract (Barij Essence brand) alone, rose extract (Barij Essence brand) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Shahid Beheshti University of Medical Sciences Iran 2020-06-29 IR.SBMU.RETECH.REC.1399.353, IRCT20190131042569N5 Phase 3 Clinical Recruiting 1 60 Nima Saeedi, Seyed Ali Ziayi 2020-08-27
A Study to Evaluate the Safety and Immunogenicity of COVID-19 (AdimrSC-2f) Vaccine Coronavirus disease 19 infection AdimrSC-2f alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Adimmune Corp Taiwan 2020-08-20 2021-03-20 ADPCT20011X, NCT04522089 Phase 1 Clinical Recruiting 1 7 Months 70 Ellie Chen, Shan-Chwen Chang, Sung-Ching Pan, Szu-Min Hsieh, Wang-Da Liu 2020-09-01
TARGET-VIP: Prospective Hospital Registry of Patients With Suspected or Confirmed Coronavirus Infection (COVID-19) and Community-acquired Pneumonia Coronavirus disease 19 infection, Pneumonia, Viral pneumonia computerized tomography alone, polymerase chain reaction alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Research Center for Preventive Medicine Pirogov National Medical Surgical Center Russian Federation 2020-04-06 2022-05-01 02-07/20, NCT04522076, TARGET-VIP Phase Not Applicable No longer recruiting 2 24 Months 1124 Andrey Pulin, MD, PhD, Mikhail Loukianov, MD, PhD, Sergey Martsevich, MD, PhD 2020-08-28
The effect of progressive muscle relaxation on covid-19 anxiety in pregnant women Anxiety disorder, Coronavirus disease 19 infection Progressive muscle relaxation technique training alone, Routine prenatal care alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tehran University of Medical Sciences Iran 2020-08-07 IR.TUMS.MEDICINE.REC.1399.287, IRCT20200630047962N1 Phase Not Applicable Recruiting 1 126 Mohammadali Sahrayian, Mojgan Zendehdel 2020-08-25
TelePark: Efficacy and feasibility of Teleneurorehabilitation in Persons with Parkinsons Disease Coronavirus disease 19 infection, Parkinsons disease Tele-Neurorehabilitation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Lady Hardinge Medical College India 2020-09-01 CTRI/2020/08/027300, TelePark Phase Not Applicable Not yet recruiting 1 100 Rajinder K Dhamija 2020-09-01
A study to find out possible causes of mortality amongst the Covid-19 patients that are admitted in GCS Medical College, Ahmedabad Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gujarat Cancer Society Medical college hospital and research centre India 2020-08-31 CTRI/2020/08/027299 Phase Not Applicable Not yet recruiting 1 600 Dr Rushi Rashmikant Patel 2020-08-25
C3-RCT: Catalyzing the Containment of COVID-19 Coronavirus disease 19 infection, HIV infection nitazoxanide alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Cape Town Aurum Institute, National Institutes of Health, Perinatal HIV Research Unit, South African Medical Research Council, Texas Tech University, University Of Kwazulu-Natal South Africa 2020-08-27 2021-08-31 C3-RCT, C3-RCT, NCT04523090 Phase 2/Phase 3 Clinical Recruiting 1 12 Months 960 Ali Esmail, MD, Keertan Dheda, Keertan Dheda, MD/PhD 2020-09-03
Effect of oral health care and mouth rinse in treatment of Covid-19 Coronavirus disease 19 infection Professional oral health care education alone, Variable regimens including betadine , chlorhexidine , povidone-iodine Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kashan University of Medical Sciences and Health Services Iran 2020-06-05 IR.KAUMS.REC.1399.015, IRCT20200527047581N1 Phase 2/Phase 3 Clinical No longer recruiting 2 200 Dr. Hamidreza Banafsheh, Dr.Mohammad Reza Sharif, Elaheh GhasemzadehHosseini, Soltan Ali Bahmani 2020-08-28
Effectiveness of Siddha Medicines Kabasura Kudineer and Nilavembu Kudineer in the Management of Smptomatic COVID 19 patients Coronavirus disease 19 infection Kaba sura Kudineer alone, Nilavembu Kuidneer  alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Central Council for Research in Siddha, Government Institute of Medical Sciences, Greater Noida India 2020-08-22 CTRI/2020/08/027286 Phase 2 Clinical Not yet recruiting 1 90 Dr ANURAG SRIVASTAVA, Dr R MANICKAVASAGM 2020-08-26
An Exploratory Study of ADR-001 in Patients With Severe Pneumonia Caused by SARS-CoV-2 Infection (COVID-19) Coronavirus disease 19 infection, Lung inflammation, Respiratory failure, Viral pneumonia ADR-001 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rohto Pharmaceutical Co Ltd Japan 2020-09-30 2021-12-31 ADR-001-1919, JapicCTI-205416, NCT04522986 Phase 1 Clinical Not yet recruiting 1 15 Months 6 Rohto Pharmaceutical Co., Ltd., Yuji Fujino, MD 2020-08-31
CLBS-119 for Repair of COVID-19 Induced Pulmonary Damage Coronavirus disease 19 infection, Lung injury, Respiratory distress syndrome, Respiratory failure, Viral pneumonia CLBS-119 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Caladrius Biosciences Inc US 2020-09-30 2021-05-31 CLBS119-P01, NCT04522817 Phase 1 Clinical Not yet recruiting 1 8 Months 12 Christine L Kotynski, Douglas W Losordo, MD 2020-08-27
Ethnic Differences in the Impact of Breast Cancer on Employment Status, Financial Situation, and Quality of Life Breast tumor, Coronavirus disease 19 infection survey web-based or telephone interview alone Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Memorial Sloan-Kettering Cancer Center City University of New York, NYC Health & Hospitals/ Lincoln Medical Center, New York City Health and Hospitals Corp, New York Presbyterian Queens, Queens Medical Associates, Ralph Lauren Center for Cancer Care and Prevention US 2010-05-31 2021-05-31 10-071, NCT01134172 Phase Not Applicable No longer recruiting 15 132 Months 935 Victoria Blinder, M.D., M.Sc. 2020-08-27
Metacognitive Therapy and Work Interventions for Patients on Sick Leave Due to Common Mental Disorders Anxiety disorder, Coronavirus disease 19 infection, Depression, Psychiatric disorder Metacognitive therapy alone, work-focused interventions alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Norwegian University of Science and Technology (NTNU) Diakonhjemmet Sykehus Norway 2017-10-31 2023-04-30 2015/1794, NCT03301922 Phase Not Applicable Recruiting 1 66 Months 240 Odin Hjemdal, phd prof, Odin Hjemdal, prof, Ragne GH Gjengedal 2020-08-28
PCCE: Primary Care Clinical Excellence Incentive Study Coronavirus disease 19 infection Leadership Training alone, Monthly email communication alone, Social comparison Intervention alone, Standard communication email alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of California Los Angeles US 2019-11-01 2021-07-01 12345, NCT04237883, PCCE Phase Not Applicable No longer recruiting 1 20 Months 225 Daniel M. Croymans 2020-08-24
A Transdiagnostic Course for Common Mental Health Problems in Primary Care Anxiety disorder, Coronavirus disease 19 infection, Depression Large-group transdiagnostic course alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Karolinska Institutet Sweden 2020-08-31 2021-12-31 2019-04816, NCT04522713 Phase Not Applicable Not yet recruiting 1 16 Months 68 Erland Axelsson, PhD 2020-09-02
A trial to evaluate Zofin for the treatment of patients with Coronavirus disease 19 infection Coronavirus disease 19 infection Zofin alone Organicell Regenerative Medicine Phase Not Applicable Status not specified 0 1 2020-08-24
TIP-OA: Telehealth Intervention Program for Older Adults Acute stress disorder, Coronavirus disease 19 infection, Psychiatric disorder Telehealth Intervention Program (TIP-OA) alone, semi-structured interviews alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Lady Davis Institute Canada 2020-10-31 2022-10-31 NCT04523610, TIP-OA, TIP-OA Phase Not Applicable Not yet recruiting 1 24 Months 258 Harmehr Sekhon, PHD, Soham Rej, MD/MSc 2020-09-04
Impact of COVID-19 on Mental Health of Patients With Skin Picking Coronavirus disease 19 infection, Psychiatric disorder Internet-based Cognitive Behavioral Therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital de Clinicas de Porto Alegre Federal University of Rio Grande do Sul Brazil 2020-08-11 2021-03-31 31520820.1.0000.5327, NCT04522492 Phase Not Applicable Recruiting 1 7 Months 20 Carolina Blaya Dreher, PhD 2020-08-27
Does Quality of Life Decline During the COVID-19 Pandemic and Can we Change Behaviour to Improve Poor Quality of Life? Coronavirus disease 19 infection extended intervention alone, online questionnaire alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Manchester UK 2020-05-22 2022-12-31 2020-9463-15184, NCT04522128 Phase Not Applicable Recruiting 1 31 Months 969 Christine Rowland, Tracy Epton 2020-08-27
NH-Shingrix: Training the Innate Immune System Against SARS-CoV-2 (COVID-19) Using the Shingrix Vaccine in Nursing Home Residents Coronavirus disease 19 infection, Influenza virus infection, Viral pneumonia GSK-1437173A alone Healthy volunteers accepted, Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Oklahoma Oklahoma Medical Research Foundation US 2020-09-30 2021-09-30 NCT04523246, NH-Shingrix, OUHSC IRB12394 Phase 0 Clinical Not yet recruiting 1 12 Months 250 Barbara Carlson, Barbara W. Carlson, RN, Ph.D., Diana L Sturdevant, RN, Ph.D. 2020-08-26
Providing Suboxone and PrEP Using Telemedicine Coronavirus disease 19 infection, HIV infection, Opiate dependence Pre-exposure prophylaxis alone, Telemedicine alone, buprenorphine hydrochloride (oral, formulated with abuse-deterrent naloxone), Indivior alone Opioid receptor kappa antagonist, Opioid receptor mu agonist Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Duke University US 2020-09-30 2021-05-31 NCT04521920, PRO00104147, PRO00104148 Phase 4 Clinical Not yet recruiting 3 8 Months 20 Hillary Chen, MPH, Hillary Murphy, MPH, Mehri McKellar, MD 2020-08-25
COCOVIH: COVID-19 and HIV Patients Coronavirus disease 19 infection, HIV infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre de Recherches et d'Etude sur la Pathologie Tropicale et le Sida France 2020-07-01 2022-06-30 COCOVIH, CREPATS 013, NCT04523012 Phase Not Applicable Recruiting 1 24 Months 2200 Valerie POURCHER, MD, Valérie Pourcher, MD, Yasmine Dudoit, valérie Pourcher, MD 2020-08-25
CODYS: Measurement of the Efficacy of Morphine in the Early Management of Dyspnea in COVID-19 Positive Patients Coronavirus disease 19 infection, Dyspnea, Respiratory disease, Respiratory distress syndrome morphine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospices Civils De Lyon France 2020-06-01 2021-02-28 CODYS, CODYS_2020, NCT04522037 Phase Not Applicable Recruiting 3 9 Months 200 Guillaume Economos, Dr, Myriam Legenne, Myriam Legenne, Dr, Sophie Francioni, Dr 2020-08-27
RECOVER: Rehabilitation After Admission in Intensive Care Unit for COVID-19 Coronavirus disease 19 infection Centre Hospitalier Régional Metz-Thionville France 2020-04-01 2021-05-01 2020-05OBS-CHRMT, NCT04523051, RECOVER Phase Not Applicable Recruiting 3 13 Months 40 Armelle Stephan-Carlier, MD, Catherine Achour, MD, Clémence Deffinis, MD, Elise Schwartz-Leduc, MD, Margaux Temperelli, MD, Nadia Ouamara, Rémi Leclaire, MD, Vincent Dinot 2020-08-26
COVID19-CED-PÄD: Online survey on clinical care, health problems and str stress during the corona pandemic in children and adolescents with chronic inflammatory bowel disease (IBD) Acute stress disorder, Coronavirus disease 19 infection, Inflammatory bowel disease online questionnaire alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Technical University of Munich Klinikum Grosshadern Der Ludwig-Maximilians-Universitat Germany 2020-08-25 20-690 KB and 20-642, COVID19-CED-PÄD, DRKS00022500 Phase Not Applicable Not yet recruiting 1 500 Elisabeth Klucker, Leandra Koletzko, Sibylle Koletzko, Thu Giang Le Thi, Tobias Schwerd 2020-08-27
A phase I clinical study to assess safety and immunogenicity of bacteriophage-based therapy COVID-19 vaccine for the potential treatment of novel coronavirus (SARS-CoV-2) Coronavirus disease 19 infection bacteriophage-based therapy COVID-19 vaccine alone Adaptive Phage Therapeutics Inc US Department of Defense Phase 1 Clinical Planned 0 2020-09-01
Photobiomodulation anti-inflammatory effect in COVID-19 Coronavirus disease 19 infection, Viral pneumonia Neolys (Life+) alone, photobiomodulation alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shaheed Beheshti Medical University Iran 2020-06-30 IR.SBMU.NRITLD.REC.1399.131, IRCT20200616047799N1 Phase 1/Phase 2 Clinical No longer recruiting 1 40 Alireza Eslaminejad, Mehran Marashian, Research department 2020-08-25
A randomized, double-blinded, placebo-controlled phase I/II clinical trial of Zofin against COVID-19 Coronavirus disease 19 infection Zofin alone Organicell Regenerative Medicine Alternative Research Associates, LLC, Larkin Community Hospital US Phase 1/Phase 2 Clinical Planned 1 20 2020-08-24
An observational study to assess the relation between previous treatment with ACE inhibitors, angiotensin-receptor blockers, beta-blockers, calcium-channel blockers, or thiazide diuretics and the likelihood of a positive or negative result on Covid-19 testing as well as the likelihood of severe illness (defined as intensive care, mechanical ventilation, or death) among patients who tested positive Coronavirus disease 19 infection ACE inhibitors (cardiovascular diseases), Jiangsu Kanion Pharmaceutical Co Ltd/China Pharmaceutical University alone, angiotensin receptor blockers (prodrug, cardiovascular diseases), KemPharm alone, beta blockers (glaucoma), University of Nottingham alone, calcium-channel blockers alone, thiazide diuretics alone ACE inhibitor, Angiotensin receptor antagonist, Beta 1 adrenoceptor antagonist National Center For Advancing Translational Sciences, National Institutes of Health, US Department of Health and Human Services Phase Not Applicable Status not specified 0 12594 2020-08-26
Evaluation of the effect of SINA anti-flu natural product on COVID-19 Coronavirus disease 19 infection, Respiratory disease Variable regimens including SINA anti-flu medicinal natural product , azithromycin , naproxen Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bagheiat-allah University of Medical Sciences Iran 2020-09-22 IR.BMSU.REC.1399.038, IRCT20160131026298N5 Phase 2/Phase 3 Clinical Not yet recruiting 1 80 AHMAD REZA SHARIFI OLOUNABADI, Ahmad Reza Sharifi Olounabadi, Gholamhosein Alishiri, mortezaazadi 2020-08-25
A clinical trial of ELI-004 for the prevention of Coronavirus disease 19 infection Coronavirus disease 19 infection ELI-004 alone TLR-9 agonist Elicio Therapeutics Phase Not Applicable Planned 0 2020-08-24
Evaluation of the effect of oral ivermectin on patients with COVID-19 Coronavirus disease 19 infection Variable regimens including azithromycin , hydroxychloroquine sulfate , ivermectin Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Tehran University of Medical Sciences Iran 2020-04-19 IR.TUMS.MEDICINE.REC.1399.031, IRCT20180922041089N4 Phase 3 Clinical No longer recruiting 3 130 Abolfazl Zendedel, Abolfazl Zendehdel, Mohammadali Sahraeeian, Saeedreza Jamali moghadam 2020-08-26
Phase III Trial of A COVID-19 Vaccine of Adenovirus Vector in Adults >/= 18 Years Coronavirus disease 19 infection Ad5-nCoV alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) CanSino Biologics Inc Institute of Biotechnology the Academy of Military Medical Sciences PLA Pakistan 2020-08-30 2022-01-30 CS-CTP-AD5NCOV-III, NCT04526990 Phase 3 Clinical Not yet recruiting 2 17 Months 40000 Aamer Ikram SI, phD, Fengcai Zhu, Jinbo Gou, MD, Joanne M angley, MD, Scott A Halperin, MD 2020-09-01
BTL-TML-COVID: A Study in Adults to Test the Effects of Low Dose Thimerosal on Symptoms of COVID-19 Coronavirus disease 19 infection BTL-TML-COVID alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Beech Tree Labs Inc Norwich Clinical Research Associates Ltd, The Curavita Corp US 2020-07-30 2020-10-30 2020-04-0311, BTL-TML-COVID, NCT04522830 Phase 2 Clinical Recruiting 1 3 Months 40 DeAnn Sims, Duane Harris, MD, Lee Truax-Bellows, Tom Hatch 2020-08-28
A Phase II, Randomized, Double-blind, Placebo-controlled, Proof-of-Concept Study to Evaluate the Safety and Efficacy of Antroquinonol in Hospitalized Patients With Mild to Moderate Pneumonia Due to COVID-19 Coronavirus disease 19 infection, Viral pneumonia antroquinonol alone MEK-1 protein kinase inhibitor, Ras gene inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Golden Biotechnology Corp 2020-09-07 2021-03-31 GHCOVID-2-001, NCT04523181 Phase 2 Clinical Not yet recruiting 0 6 Months 174 2020-08-26
A case-series of Herpes zoster infections in COVID‐19‐positive patients Coronavirus disease 19 infection, Varicella zoster virus infection hydroxychloroquine alone, mechanical ventilation alone, tocilizumab alone Universita di Bologna Phase Not Applicable Status not specified 0 4 2020-08-25
A clinical study based on novel Coronavirus intelligent robot for nasopharyngeal swab sampling Coronavirus disease 19 infection nasopharyngeal swab sampling alone, novel Coronavirus intelligent robot alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shuguang Hospital Shanghai University Of Traditional Chinese Medicine China 2020-10-01 2022-09-30 ChiCTR2000035985 Phase 0 Clinical Not yet recruiting 1 24 Months Bin Shen 2020-08-31
PAMOCOS: Proadrenomedullin Assessment of Multi-Organ Failure in Covid-19 Sepsis Coronavirus disease 19 infection, Multiple organ failure, Sepsis, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier De Lens France 2020-05-20 2020-10-07 2020-05, NCT04522310, PAMOCOS Phase Not Applicable Recruiting 8 4 Months 183 CLAIRE BOULLE, Dr, CLEMENT DELPIERRE, Dr, DELPHINE COLLING, Dr, FABIEN LAMBIOTTE, Dr, GUILLAUME BRUNIN, Dr, KATHY DERNIVOIX, MELANIE VERLAY, Mélanie VERLAY, Nicolas VAN GRUNDERBEECK, Dr, SEBASTIEN BEAGUE, Dr, THOMAS CAULIER, Dr 2020-08-28
Using Mindfulness to Reduce Anxiety and Depression of Patient with Fever Undergoing Screening in an Isolation Ward During novel coronavirus pneumonia (COVID-19) pandemic Anxiety disorder, Coronavirus disease 19 infection, Depression, Pneumonia short-term mindfullness intervention alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) The Second XiangYa Hospital of Central South University China 2020-01-30 2020-04-30 ChiCTR2000036333 Phase Not Applicable Completed 1 3 Months 51 Jin Huang, Sizhu Huyang 2020-09-03
Multi-center study on intelligent accurate diagnosis and critical illness prediction of novel coronavirus pneumonia (COVID-19) with multimodal imaging Coronavirus disease 19 infection, Pneumonia Etiological examination alone, multimodal imaging alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shanghai Public Health Clinical Center Shanghai shen-kang hospital clinical development center China 2020-10-01 2023-11-01 ChiCTR2000036217 Phase 0 Clinical Not yet recruiting 4 37 Months 4000 Yuxin Shi 2020-08-27
Study of host genome variants in association to the varying severity of COVID-19 symptoms in Sabah patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universiti Malaysia Sabah Malaysia 2020-09-01 2022-09-22 55933, NMRR-20-1785-55933 Phase Not Applicable Not yet recruiting 1 24 Months Dr Lee Heng Gee, Professor Dr. Lee Ping Chin 2020-08-27
The Efficacy of Early Prone or Lateral Positioning in Severe COVID-19 Patients: a Single-Center, Prospective, Cohort Study Coronavirus disease 19 infection, Viral pneumonia Lateral Positioning alone, Prone Positioning alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) West China Hospital China 2020-01-31 2020-02-15 ChiCTR2000035907 Phase 0 Clinical No longer recruiting 1 197 Liu Dan, Ni Zhong 2020-08-31
Evaluation of the course of COVID-19 and perceptions among those tested positive – a survey based study Coronavirus disease 19 infection survey alone University of Heidelberg Gesundheitsamt Rhein-Neckar Germany 2020-03-22 DRKS00022926, S-179/2020 Phase Not Applicable Suspended 1 1000 Claudia Denkinger 2020-08-27
AVID-CC: Adalimumab for coronavirus in community care Coronavirus disease 19 infection, Respiratory failure Standard care alone, adalimumab biosimilar, Sandoz alone TNF alpha ligand inhibitor, TNF binding agent Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Oxford Wellcome Trust UK 2020-07-01 2021-12-31 2020-003628-18, AVID-CC, IRAS 287434, ISRCTN33260034 Phase 2 Clinical Not yet recruiting 2 18 Months 750 Prof Richards 2020-08-26
A retrospective study to evaluate systematic assessment of venous thromboembolism (VTE) using complete duplex ultrasound (CDU) in anticoagulated COVID-19 patients Coronavirus disease 19 infection Complete duplex ultrasound alone, prophylactic anticoagulation therapy alone, therapeutic anticoagulation therapy alone Cochin Institute France Phase Not Applicable Status not specified 1 26 2020-08-24
A prospective, observational study to characterize the coagulation profile of COVID-19 ARDS patients with standard and viscoelastic coagulation tests and to evaluate their changes after establishment of an aggressive thromboprophylaxis Coronavirus disease 19 infection, Respiratory distress syndrome clopidogrel alone, coagulation profiling alone, heparin alone, thromboprophylaxis alone P2Y12 purinoceptor antagonist IRCCS Policlinico San Donato Phase Not Applicable Status not specified 0 16 2020-08-24
A case-series study to evaluate the efficacy of tissue plasminogen activator (tPA) treatment for COVID-19 associated acute respiratory distress syndrome (ARDS) Coronavirus disease 19 infection, Respiratory distress syndrome alteplase alone Tissue plasminogen activator stimulator Beth Israel Deaconess Medical Center, Harvard University, University of Colorado System Phase Not Applicable Status not specified 0 3 2020-08-24
Epidemiological Analysis of Ambulant Patients in a COVID-19 Outpatient Clinic Coronavirus disease 19 infection Wissenschaftliches Institut Bethanien e.V. Germany 2020-07-02 2020-12-31 NCT04521088, WI-1252 Phase Not Applicable Recruiting 1 5 Months 1000 Prof. Randerath, Prof. Dr, Simon Herkenrath 2020-08-26
AT-301 Nasal Spray in Healthy Adults Coronavirus disease 19 infection AT-301 (nasal spray, COVID-19), Atossa Therapeutics alone COVID19 Spike glycoprotein inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Atossa Therapeutics Inc, Avance Clinical Pty Ltd Australia 2020-08-07 2020-12-01 ACTRN12620000816954, AT-301-AU-01, NCT04519788 Phase 1 Clinical Recruiting 2 3 Months 50 Ben Canny, Dr Heather Fraser, Emir Redzepagic, MD, Jane Kelly, Meridee Arthur 2020-08-31
Impact of the COVID-19 pandemic and the political measures to contain its spread on children with disabilities and chronic illnesses and their families Coronavirus disease 19 infection Healthy volunteers accepted, Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Universitätsklinik Freiburg Klinik für Allgemeine Kinder und Jugendmedizin Klinik für Neuropädiatrie und Muskelerkrankungen Germany 2020-09-01 377/20, DRKS00022868 Phase Not Applicable Not yet recruiting 1 800 Thorsten Langer 2020-08-25
A phase I clinical trial of Ad26.COV2.S for potential treatment of COVID-19 infection Coronavirus disease 19 infection JNJ-78436735 alone Johnson & Johnson Brazil Phase 1 Clinical Planned 1 6000 2020-08-21
A clinical trial of urokinase plasminogen activator receptor targeted radio-immuno-therapeutics (uPRITs) for the potential treatment of patients with severe COVID-19 Coronavirus disease 19 infection urokinase plasminogen activator receptor targeted radio-immuno-therapeutics (uPRITs) alone Monopar Therapeutics LLC, Northstar Medical Radioisotopes Llc Aragen Bioscience Inc Phase Not Applicable Planned 0 2020-08-24
CARR-COV-02: Efficacy of a Nasal Spray Containing Iota-Carrageenan in the Prophylaxis of COVID-19 Disease in Health Personnel Dedicated to Patients Care With COVID-19 Disease Coronavirus disease 19 infection Iota-Carrageenan alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centro de Educación Medica e Investigaciones Clínicas Norberto Quirno Argentina 2020-07-24 2020-11-30 CARR-COV-02, CEMIC, NCT04521322 Phase 4 Clinical Recruiting 1 4 Months 400 Ariel Dogliotti, Juan Figueroa, MD, Mónica Lombardo, MD, Ricardo Valentini, MD, Ricardo c Valentini 2020-08-25
No-SARS: Antibodies Responses to COVID-19 Infection in Hospitalized Patients Coronavirus disease 19 infection ELISA alone, Luciferase assay alone, Luminometer alone, PV microneutralization assay alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Dammam Dammam Medical Complex, Institute for Research and medical consultation Saudi Arabia 2020-08-31 2021-02-28 ICU-06072020, NCT04520880, No-SARS Phase Not Applicable Not yet recruiting 1 6 Months 158 Amani MM Alnimr, MD, Fatimah A Al-Mishkab, MD, Hisham A Almuzayyen, MD, Iman Almansour, Ph.D., Iman Almansour, PhD, Jawaher Almusairii, MD, Laila P Asonto, MD, Moaz S Alammar, MD, Mohamed R El Tahan, MD, Mohammed Alnabi, MD, Mohammed S Alshahrani, MD, Mohammed SS Alshahrani, MD, Talal A Albrahim, MD, Yousef Al Mubarak, MD 2020-08-24
Staff Absenteeism and Delivery of Healthcare Services During the COVID-19 Pandemic Coronavirus disease 19 infection Poznan University of Medical Sciences Poland 2020-01-01 2020-04-30 3/2020/REH, NCT04521010 Phase Not Applicable Completed 1 4 Months 700 Ewa Chlebuś, MD 2020-08-21
MWLAHCW-COV: Mental workload assessment among healthcare worker among healthcare worker during pandemic COVID-19 at hospital Tunku Azizah (hospital kuala lumpur) Coronavirus disease 19 infection Hospital Tunku Azizah Malaysia 2020-08-30 2020-12-31 54627, MWLAHCW-COV, NMRR-20-1769-54627 Phase Not Applicable Not yet recruiting 1 4 Months Mr. MOHD ' AIZAT BIN MOHD BASARI 2020-08-25
The effect of herbal tea on improving respiratory symptoms in patients with Covid-19 Coronavirus disease 19 infection, Respiratory disorder herbal tea alone, routine treatment alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Isfahan University of medical Sciences Iran 2020-09-22 IR.MUI.MED.REC.1399.359, IRCT20200806048318N1 Phase 3 Clinical Not yet recruiting 1 80 Mehdi Akhve, Mehdi Akhveh, Shaghayegh Haghjoo Javanmard 2020-08-26
Characteristics in Post COVID-19 Patients Coronavirus disease 19 infection aerobic exercises alone, anaerobic exercises alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidade Metodista de Piracicaba Brazil 2020-08-11 2021-12-31 F110820, NCT04514705 Phase Not Applicable Recruiting 1 16 Months 20 Luiz F Falcão, PhD, Rodrigo S Rocha, Phd, Rodrigo Santiago Barbosa Rocha 2020-08-24
PRONE: Prone Position and Respiratory Outcomes in Non-Intubated COVID Patients Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia prone positioning alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Johns Hopkins University Duke University, Nox Medical, Smith & Nephew Inc, University of Miami, University of North Carolina, University of Pittsburgh 2020-09-01 2021-12-31 IRB00249663, NCT04517123, PRONE Phase Not Applicable Not yet recruiting 0 16 Months 100 Mahendra Damarla, Naresh Punjabi, MD 2020-08-24
A clinical trial of autologous stromal vascular fraction for the treatment of severe respiratory distress due to COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome autologous stromal vascular fraction alone GID BIO Richard King Mellon Foundation Phase Not Applicable Planned 0 2020-08-21
FERMIN: Fenofibrate as a Metabolic Intervention for COVID-19 Coronavirus disease 19 infection fenofibrate (micronized), Fournier/Abbott alone, usual care alone Lipoprotein lipase stimulator, PPAR alpha agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Pennsylvania University of Arizona US 2020-08-18 2021-08-31 843729, FERMIN, NCT04517396 Phase 3 Clinical Recruiting 1 12 Months 300 Julio A. Chirinos 2020-08-28
The Investigation Into Beneficial Effects of High-dose Interferon Beta 1-a, Compared to Low-dose Interferon Beta 1-a in Moderate to Severe COVID-19 Coronavirus disease 19 infection interferon beta-1a follow-on biologic (subcutaneous), CinnaGen plus lopinavir + ritonavir HIV protease inhibitor, Interferon beta ligand Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shaheed Beheshti Medical University Iran 2020-08-20 2020-09-11 INTERFERON IN COVID, NCT04521400 Phase 2 Clinical Not yet recruiting 1 100 Behnam Rahimi, M.D, Firouze Hatami, M.D, Ilad Alavi Darazam, Ilad Alavi Darazam, M.D, Ilad Alavi Darazam, MD, Minoosh Shabani, M.D, Mohammad Mahdi Rabiei, M.D, Mohammad Reza Hajesmaeili, M.D, Omid Moradi, Seyed Sina Naghibi Irvani, M.D, Shervin Shokouhi, M.D 2020-08-24
Enhancement: Home-based Kidney Care in Native Americans of New Mexico (HBKC) Coronavirus disease 19 infection, Diabetes mellitus, End stage renal disease home-based kidney care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Native American Ancestry University of New Mexico Albuquerque area indian health board US 2020-09-01 2021-09-30 16-344-ENHANCEMENT, Enhancement, NCT04520191 Phase Not Applicable Not yet recruiting 1 13 Months 529 Vallabh O Shah, Vallabh Shah, PhD 2020-08-25
A Phase III clinical trial of Cannabis sativa for the treatment of COVID-19 and other infectious diseases Coronavirus disease 19 infection Cannabis sativa alone Asia Green Biotechnology Corp, Pathway Rx Inc Phase 3 Clinical Planned 0 15 2020-08-21
A Phase II clinical trial of Cannabis sativa for the treatment of COVID-19 and other infectious diseases Coronavirus disease 19 infection Cannabis sativa alone Asia Green Biotechnology Corp, Pathway Rx Inc 2021-01-31 Phase 2 Clinical Planned 0 300 2020-08-21
A clinical trial of replicating vesicular stomatitis virus vector-based vaccine (COVID-19), Israel Institute for Biological Research/Weizmann Institute of Science for the prevention of Covid-19 Coronavirus disease 19 infection VSV vector-based vaccine targeting spike glycoprotein (COVID-19), IIBR/Weizmann Institute of Science alone COVID19 Spike glycoprotein modulator Israel Institute for Biological Research Ministry of Health, Israel Israel 2020-10-31 Phase Not Applicable Planned 1 2020-08-26
SARS-CoV-2 Antibodies Based IVIG Therapy for COVID-19 Patients Coronavirus disease 19 infection SARS-CoV-2 antibodies based IVIG therapy, Dow University alone, airway support therapy alone, anti-pyretic therapy alone, anti-viral medication therapy alone, antibiotic treatment alone, fluid resuscitation alone, hemodynamic support treatment alone, painkiller treatment alone, steroid therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dow University of Health Sciences Higher Education Commission of Pakistan Pakistan 2020-06-19 2021-03-31 BIOTECH001, NCT04521309 Phase 1/Phase 2 Clinical Recruiting 1 9 Months 50 Dr. Mohsin Bajwa, FCPS, Dr. Muneeba Sayeed, FCPS, Dr. Shaukat Ali, PhD, Dr. Sheikh Muhammad Muhaymin, MBBS, Dr. Shobha Luxmi, FCPS, Dr.Shaukat Ali, PhD, Mr. Abdul Samad Khan, M.Phil, Mr. Elisha Shalim, BS, Mr. Mir Rashid Ali, M.Sc, Mr. Mujtaba Khan, BS, Mr. Syed Muneeb Uddin, M.Sc, Ms. Ayesha Ali, M.Sc, Ms. Fatima Anjum, M.Sc, Prof. Dr. Mohammed Saeed Quraishy, FRCS, Prof. Dr. Mohammed Saeed Quraishy, FRCS, FCPS, Shaukat Ali, PhD, Shobha Luxmi, FCPS 2020-09-05
A clinical trial of COVID-19 vaccine (inactivated, Vero cells/intramuscular), Wuhan Institute of Biological Products/Wuhan Institute of Virology, CAS for the treatment of Covid-19 Coronavirus disease 19 infection COVID-19 vaccine (inactivated, Vero cells/intramuscular), Wuhan Institute of Biological Products/Wuhan Institute of Virology, CAS alone Sinopharm China National Biotech Institute Co Ltd, Thomson Reuters Corp Peru, Morocco Phase 3 Clinical Recruiting 2 2020-08-21
A placebo-controlled, randomized, double-blind, phase I clinical study to assess BT-20 in the treatment of patients with COVID-19 infection Coronavirus disease 19 infection, Respiratory distress syndrome BT-20, Bone Therapeutics alone, standard supportive treatment alone Bone Therapeutics SA Belgium Phase 1 Clinical Planned 1 2020-08-26
ReMiCov: Retinal Microangiopathy in Patients after Covid-19 Disease Coronavirus disease 19 infection, Microangiopathy optical coherence tomography angiography alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hannover Medical School Germany 2020-07-13 9159_BO_K_2020, DRKS00022874, ReMiCov Phase Not Applicable Recruiting 1 66 Jan Tode 2020-08-25
A phase I trial of COVID-19 vaccine(vaxipatch technology)for the potential treatment of COVID-19 Coronavirus disease 19 infection COVID-19 vaccine (vaxipatch technology, COVID-19 infection) Verndari/University of California Davis alone COVID19 Spike glycoprotein modulator Verndari Inc US Phase 1 Clinical Planned 1 2020-08-28
Efficacy and Safety of DWJ-1248 in Patients With Mild to Moderate COVID-19 Compared to the Placebo Coronavirus disease 19 infection repurposed camostat mesilate (oral, COVID-19), Daewoong/Institut Pasteur Korea/Korea Institute of Radiological and Medical Sciences alone Serine protease inhibitor, Transmembrane serine protease 2 inhibitor, Trypsin inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Daewoong Pharmaceutical Co Ltd 2020-08-31 2020-12-31 DW_DWJ1248201, NCT04521296 Phase 2 Clinical Not yet recruiting 0 4 Months 90 2020-09-03
CPCP: Convalescent Plasma for COVID-19 Patients Coronavirus disease 19 infection convalescent plasma alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Vinmec Research Institute of Stem Cell and Gene Technology National Hospital Of Tropical Diseases, National Institute of Hematology and Blood Transfusion, Vietnam, National Institute of Hygiene and Epidemiology, Vietnam Vietnam 2020-12-01 2021-10-30 CPCP, ISC.20.11.2, NCT04521036 Phase 1/Phase 2 Clinical Not yet recruiting 1 10 Months 44 Liem Thanh Nguyen, PhD, Phuong Hoang Nguyen, MPH 2020-09-03
A single-center, retrospective and observational study to assess famotidine in the treatment of patients with severe COVID-19 Coronavirus disease 19 infection famotidine alone Histamine H2 receptor antagonist Hartford Hospital US Phase Not Applicable Status not specified 1 83 2020-08-21
iGenes-COVID19: Investigating the Involvement of ACE and Angiotensinogen Genes' Polymorphism Along With Other Thrombophilic Genotypes in Severe Forms of COVID-19 With/Without Thrombotic Events Arterial thrombosis, Coronavirus disease 19 infection, Cough, Deep vein thrombosis, Fever, Lung embolism, Myalgia, Myocardial infarction, Phlebothrombosis, Stroke multiplex PCR alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Grigore T. Popa University of Medicine and Pharmacy Romania 2020-08-18 2021-08-18 GTP0051, NCT04519398, iGenes-COVID19 Phase Not Applicable Recruiting 1 12 Months 60 Adrian Covic, Professor, Alexandru Burlacu, Lecturer, Alexandru Burlacu, MD, PhD, Iolanda Popa, MD, PhD, Radu Crisan-Dabija, Lecturer, Radu Crisan-Dabija, MD, PhD 2020-08-25
The effect of selenium, vitamin C and methylprednisolone combination on mortality and morbidity of COVID-19 patients Coronavirus disease 19 infection, Respiratory distress syndrome Variable regimens including hydroxychloroquine , lopinavir + ritonavir , methylprednisolone , selenium , vitamin C HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tabriz University of Medical Sciences Iran 2020-06-29 IR.TBZMED.REC.1399.340, IRCT20190312043030N2 Phase 3 Clinical Recruiting 1 40 Dr Abolghasem Joyban, Dr.Seied Hadi Saghaleini 2020-08-25
SPP – SmartPointer Pilot study: Pilot study to investigate the SmartPointer system in the context of domestic life with older people in need of support Aging, Coronavirus disease 19 infection SmartPointer (SP) system alone Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Charite Universitaetsmedizin Berlin Bundesministerium fur Bildung und Forschung Germany 2020-12-01 DRKS00022533, EA1/137/20, SPP – SmartPointer Pilot study, U1111-1256-0263 Phase Not Applicable Not yet recruiting 1 117 Susan Vorwerg 2020-08-21
Transpulmonary Pressure Measurements in Intubated Children With Covid-19 Respiratory Failure Coronavirus disease 19 infection, Respiratory failure transpulmonary pressure measurement alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) Mayo Clinic, Minnesota US 2020-05-21 2021-01-31 20-003743, NCT04519411 Phase Not Applicable Recruiting 1 8 Months 10 Stephen Gleich, M.D., Stephen J Gleich, MD 2020-08-25
MFMU COVID-19: Maternal Morbidity and Mortality During the COVID-19 Pandemic Coronavirus disease 19 infection, Pregnancy disorder Female The George Washington University Biostatistics Center Eunice Kennedy Shriver National Institute of Child Health & Human Development US 2020-06-23 2021-12-31 HD36801 - MFMU COVID-19, MFMU COVID-19, NCT04519502, U01HD036801 Phase Not Applicable Recruiting 12 18 Months 26400 Alan T. Tita, MD, Amber Sowles, RN BSN CORP, Andrew Bremer, MD, PhD, MAS, Anna Bartholomew, RN,BSN,CCRP, Ashley Salazar, MSN, Cora MacPherson, PhD, Cynthia Gyamfi-Bannerman, MD, Donna Allard, RN, Dwight J Rouse, MD, Felecia Ortiz, RN,BSN,CCRC, Gail Mallett, RN,BSN, CCRC, George R Saade, MD, Hyagriv Simhan, MD, MS, Janatha Grant, BSN, Jennifer Bailit, MD, Jennifer Craig, BSN, John M. Thorp Jr., MD, Kelly Clark, RN BSN, Maged Costantine, MD, Melissa Bickus, BS, RN, Rebecca Clifton, PhD, Sabine Bousleiman, RNC MSN, Samuel Parry, MD, Suneet Chauhan, MD, Torri Metz, MD, Wendy Dalton, RNC, William Grobman, MD 2020-08-24
Covid-Screen Quality Control: SARS-CoV-2 /COVID-19 Admission Screening in a University Hospital Setting Coronavirus disease 19 infection nasopharyngeal sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Basel Switzerland 2020-04-01 2021-03-31 2020-00808, Covid-Screen Quality Control, NCT04519372 Phase Not Applicable No longer recruiting 1 12 Months 4099 Sarah Tschudin-Sutter, Prof. Dr. MD 2020-09-01
DALIA: Evaluation of the effect and the safety of the CIGB-258 peptide in the treatment of severe or critical patients due to COVID-19 Coronavirus disease 19 infection CIGB-258 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Center for Genetic Engineering and Biotechnology, Consejo Nacional de Ciencia y Tecnología, Mexican Health Research Coordination Mexico 2020-08-11 DALIA, IG/CIGB-258I/CV/2001, RPCEC00000330 Phase 2 Clinical Not yet recruiting 1 60 Francisco Hernandez Bernal, Juan Anda Garay 2020-08-31
A clinical trial of AV-001 for the treatment of COVID-19-associated acute lung injury and acute respiratory distress syndrome (ARDS) Acute lung injury, Coronavirus disease 19 infection, Respiratory distress syndrome AV-001, Vasomume Therapeutics alone Tek tyrosine kinase receptor stimulator Vasomune Therapeutics Inc Phase Not Applicable Planned 0 2020-08-26
Determination of the Hemoadsorption Impact as Adjunctive Treatment Upon the Support Therapy of COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome CytoSorb alone, continuous renal replacement therapy alone, fluid challenge alone, inotropic support alone, mechanical ventilation alone, vasopressor therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Brugmann University Hospital Belgium 2020-05-03 2020-12-01 BRUGMANNUH 1066, NCT04518969 Phase Not Applicable Recruiting 1 6 Months 24 Dr David DE BELS, Patrick Honore, MD, Patrick Honoré, MD 2020-09-01
A clinical trial of AK-119 for the treatment of COVID-19 patients Coronavirus disease 19 infection AK-119 alone CD73 antagonist Akeso Biopharma Inc New Zealand Phase Not Applicable Planned 1 2020-08-20
External pilot study to evaluate the feasibility of the development of a pragmatic clinical trial to determine the clinical utility of the repositioning of Pentoxifylline as an immunomodulator and regulator of the Renin Angiotensin system in the treatment of COVID-19 Coronavirus disease 19 infection pentoxifylline alone Phosphoric diester hydrolase inhibitor IMSS General Hospital of Zone 2A "Troncoso" Mexico 2020-785-079 Phase 4 Clinical Status not specified 1 50 2020-08-24
Epidemiological survey of COVID-19 patients in Japan Coronavirus disease 19 infection Hiroshima University Japan 2020-05-12 UMIN000041450 Phase Not Applicable Recruiting 1 10000 Nobuaki Shime, Shinichiro Ohshimo 2020-08-24
COVID-19 in Lahad Datu Coronavirus disease 19 infection, Viral pneumonia Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) HOSPITAL LAHAD DATU Malaysia 2020-08-16 2020-12-15 55950, NMRR-20-1756-55950 Phase Not Applicable Status not specified 1 4 Months 54 Dr CHEO SENG WEE 2020-08-31
MKK-COVID-19: Health Awareness Model and COVID-19 Outbreak Containment Behavior Among Sri Petaling Mosque Clusters Coronavirus disease 19 infection Institute for Health Behavioural Research (IHBR) Malaysia 2020-08-31 2021-01-31 55269, MKK-COVID-19, NMRR-20-1760-55269 Phase Not Applicable Status not specified 2 5 Months Mr Abu Bakar Bin Rahman 2020-08-21
Vitamin D Status and Immune-inflammatory Status in Different UK Populations With COVID-19 Infection Coronavirus disease 19 infection Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Guy's & St Thomas' Hospital NHS Trust UK 2020-09-01 2020-12-31 285176, NCT04519034 Phase Not Applicable Not yet recruiting 1 4 Months 27000 Agata Sobczynska-Malefora, PhD, Rachel Fay, Ms 2020-08-21
A study to assess risk of mortality and  current health characteristics of Covid-19 patients Coronavirus disease 19 infection LifeBridge Health, PeraHealth, Sinai Hospital of Baltimore, Yale New Haven Health US Phase Not Applicable Status not specified 2 2020-08-20
TRACE: Transmission of Covid-19 in Crowded Environments Coronavirus disease 19 infection STOPCOV alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Desmond Tutu HIV Foundation European and Developing Countries Clinical Trials Partnership, University of Cape Town South Africa 2020-08-03 PACTR202008485004797, TRACE Phase Not Applicable Not yet recruiting 7 720 Catherine Orrell, Lara Fairall, LindaGail Bekker, Philip Smith 2020-08-31
COV-RECUP: Medium and Long Term Follow-up of COVID-19 Infected Patients: Research and Characterization of Pulmonary Sequelae Coronavirus disease 19 infection, Viral pneumonia CT Scan alone, Pulmonary function testing alone, Ventilatory polygraphy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University Hospital of Besancon France 2020-05-18 2025-08-18 2020/499, COV-RECUP, NCT04519320 Phase Not Applicable Recruiting 1 63 Months 140 Eberst Guillaume, PH, Guillaume Eberst, PH, Lucie Laurent, PhD 2020-09-01
A follow-up study to evaluate Lucid Robotic System to generate additional findings on the pathophysiology of COVID-19 Coronavirus disease 19 infection Lucid Robotic System alone NovaSignal Corp Phase Not Applicable Status not specified 0 2020-08-20
A study to evaluate Lucid robotic system to remotely assess and monitor critically ill patients with COVID-19 Coronavirus disease 19 infection, Viral pneumonia Lucid robotic system alone NovaSignal Corp Phase Not Applicable Status not specified 0 18 2020-08-20
Evaluation of Newborns Presenting With Suspected COVID-19 Coronavirus disease 19 infection, Respiratory disease Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dr. Behcet Uz Children's Hospital Turkey 2020-03-01 2020-08-31 2020/251, NCT04519307 Phase Not Applicable No longer recruiting 1 6 Months 72 Senem Alkan Özdemir 2020-08-23
Daily Regimen of Tenofovir/Emtricitabine as Prevention for COVID-19 in Health Care Personnel in Colombia Coronavirus disease 19 infection personal protective equipment (PPE) alone, tenofovir disoproxil fumarate + emtricitabine (fixed dose), Gilead Sciences alone HIV-1 reverse transcriptase inhibitor, Nucleoside reverse transcriptase inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hospital Universitario San Ignacio Colombia National University Hospital, Fundación Universitaria Autónoma de Las Américas, Hospital Universitario San Jorge de Pereira, Hospital de la Samaritana, Sede Bogotá y Sede Zipaquirá, Javeriana University, Universidad Tecnológica de Pereira Colombia 2020-08-30 2021-04-01 2020 /143, 77389, NCT04519125 Phase 2/Phase 3 Clinical Not yet recruiting 1 7 Months 950 Juliana Maria Cuervo Rojas, MD. MSc. PhD., Sandra Liliana Valderrama, MD, Sandra Valderrama- Beltrán, MD. Msc. 2020-08-23
Adapt Out COVID: A Study for Outpatients With COVID-19 Coronavirus disease 19 infection LY-CoV555 alone COVID19 Spike glycoprotein modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Allergy and Infectious Diseases AIDS Clinical Trials Group, Eli Lilly & Co US 2020-08-19 2021-02-28 38742, A5401/ACTIV-2, Adapt Out COVID, NCT04518410 Phase 2/Phase 3 Clinical Recruiting 5 6 Months 2000 Becky Straub, Beverly Woddward, Chris Jonsson, David Smith, MD, MAS, Ericka Patrick, Jay Dwyer, Lisa Kessels, Mario Guerrero, Roberto Aguirre, Samantha Fortier, Suzanne Fiorillo, Theresa Flynn, Valery Hughes 2020-09-05
Telemedical Risk Assessment and Preoperative Evaluation (TAPE) Anesthesia, Coronavirus disease 19 infection TAPE Software alone, Telemedicine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Docs in Clouds Telecare GmbH, Rheinisch-Westfaelische Technische Hochschule Aachen Germany 2020-04-20 2020-11-30 19-174, NCT04518514 Phase Not Applicable Recruiting 1 7 Months 100 Andreas Follmann, Dr., Jan Wienhold, cand. med. 2020-08-22
FLOWER: Fixed Low-dose Eltrombopag and rhTPO for Immune Thrombocytopenia Coronavirus disease 19 infection, Immune thrombocytopenic purpura eltrombopag plus recombinant human thrombopoietin (sc, idiopathic thrombocytopenic purpura/thrombocytopenia/aplastic anemia), 3SBio Thrombopoietin receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) People's Hospital Peking University China 2020-08-31 2022-06-30 FLOWER, ITP-PKU019, NCT04518878 Phase 1 Clinical Recruiting 1 22 Months 30 Xiaohui Zhang, Xiaohui Zhang, MD, Xuelin Dou, MD 2020-09-03
Toclizumam Versus Dexamethasone in Severe Covid19 Cases Coronavirus disease 19 infection Variable regimens including azithromycin , hydroxychloroquine , methylprednisolone (Pfizer) , tocilizumab Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) South Valley University Egypt 2020-03-01 2020-08-05 NCT04519385, SOUTHVU Phase 2 Clinical Completed 1 5 Months 69 Alaa R rashad, MD 2020-08-21
Study for Quantitative Analysis of the Recovered COVID-19 Patients by [18]F-FDG-PET/CT Coronavirus disease 19 infection [18]F-FDG alone, computed tomography alone, positron emission tomography alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fifth Affiliated Hospital, Sun Yat-Sen University China 2020-07-01 2023-07-31 NCT04519255, ZDWY.FZYX.008 Phase Not Applicable No longer recruiting 1 37 Months 60 Hong Shan, Ph.D 2020-08-21
CSL-324 in COVID-19 Coronavirus disease 19 infection, Viral pneumonia Standard of care alone, CSL-324 plus remdesivir COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, GCSF receptor antagonist, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) CSL Behring, CSL Ltd 2020-08-31 2021-05-31 CSL324_COVID-19, NCT04519424 Phase 2 Clinical Not yet recruiting 0 9 Months 124 2020-08-21
A clinical study to assess XoGlo in the treatment of COVID-19 related inflammatory disease Coronavirus disease 19 infection, Inflammatory disease, Respiratory distress syndrome XoGlo alone Kimera Labs US Phase Not Applicable Planned 1 160 2020-08-20
A human-challenge trial to evaluate CodaVax-COVID in healthy subjects Coronavirus disease 19 infection CodaVax-COVID alone Healthy volunteers accepted Codagenix Inc Phase Not Applicable Planned 0 2020-08-20
CORONA: Evolution of COVID-19 in Anticoagulated or Antiaggregated Patients Coronavirus disease 19 infection acenocoumarol alone, apixaban alone, aspirin alone, cangrelor alone, clopidogrel alone, dabigatran etexilate mesylate alone, dipyridamol alone, edoxaban alone, prasugrel alone, rivaroxaban alone, ticagrelor alone, vitamin K antagonist therapy alone, warfarin alone Factor IIa antagonist, Factor IX antagonist, Factor VII antagonist, Factor X antagonist, Factor Xa antagonist, P2Y12 purinoceptor antagonist, Protease-activated receptor-1 antagonist, Vitamin K epoxide reductase inhibitor Fundacio Institut De Recerca De L'Hospital De La Santa Creu I Sant Pau Spain 2020-04-01 2020-06-30 CORONA, IIBSP-COV-2020-24, NCT04518735 Phase Not Applicable Completed 1 3 Months 1707 2020-08-21
On-Line Collectives in Mental Health: Transdisciplinary Action for Groups Vulnerable to COVID-19 Coronavirus disease 19 infection online intervention sessions alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul Universidado de Passo Fundo Brazil 2020-07-15 31919020.6.1001.5342, 4.164.222, RBR-4vy54v, U1111-1253-9181 Phase Not Applicable Not yet recruiting 1 500 Ana Luisa Sant'Anna Alves, Silvana Alba Scortegagna 2020-08-21
Study Assessing the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Repeated Subcutaneous Doses of Anti-Spike (S) SARS-CoV-2 Monoclonal Antibodies (REGN-10933 + REGN-10987) in Adult Volunteers as Related to COVID-19 Coronavirus disease 19 infection REGN-CoV2 alone COVID19 Spike glycoprotein inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Regeneron Pharmaceuticals Inc US 2020-07-26 2021-07-06 NCT04519437, R10933-10987-HV-2093 Phase 1 Clinical Recruiting 4 11 Months 420 Clinical Trial Management, Clinical Trials Administrator 2020-08-21
COVIDDEPERINAT: Effect of Tele-consultation in Addition With Psychiatric Follow-up During COVID-19 in Women Who Have Medical History of Post-partum Depression Anxiety disorder, Coronavirus disease 19 infection, Postnatal depression tele-consultation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-09-30 2020-09-30 APHP200878, COVIDDEPERINAT, NCT04516668 Phase Not Applicable Not yet recruiting 1 250 Emmanuelle Corruble, Pr, Florence Gressier, Dr 2020-08-21
Renal Biomarkers in AKI and COVID-19 Coronavirus disease 19 infection, Renal injury, Viral pneumonia metabolomic test alone, tocilizumab alone, urinary IGFBP7 test alone, urinary IL-6 test alone, urinary NGAL test alone, urinary TIMP-2 test alone, viral load test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto Nacional de Enfermedades Respiratorias Mexico 2020-06-01 2020-09-30 C26-20, NCT04517630 Phase Not Applicable Recruiting 1 4 Months 90 Amy B. Peralta Prado, MD, Santiago Avila Rios, PhD, Santiago Avila Ríos, PhD, Santiago Ávila Ríos, PhD 2020-08-22
COMETS: Coronavirus Studied by Metagenomics in ARDS COVID-19 Patients Coronavirus disease 19 infection, Respiratory distress syndrome MetaMIC software alone, Nextera XT kit alone, NovaSeq (Illumina) alone, QiaSymphony alone, Stranded TruSeq Total RNA (Illumina) alone, biological sampling alone, metagenomic and transcriptomic analysis alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-03-09 2020-12-31 APHP200418, COMETS, NCT04516486 Phase Not Applicable No longer recruiting 1 9 Months 180 Christophe Rodriguez, PharmD, PhD 2020-08-21
COVID-19 and SARS-CoV-2 Detection in Saliva Coronavirus disease 19 infection TaqPath RT-PCR alone, biological sampling alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ambry Genetics Corp Crozer-Keystone Health System, St. Joseph Hospital of Orange, The Saratoga Hospital US 2020-05-21 2020-12-30 COV_20_001, NCT04517682 Phase Not Applicable Recruiting 1 7 Months 300 Brigette Tippin Davis, PhD 2020-08-26
CONVINCE: Corona Virus Edoxaban Colchicine (CONVINCE) COVID-19 Coronavirus disease 19 infection, Thrombosis colchicine alone, edoxaban alone, colchicine plus edoxaban Factor Xa antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Inselspital, Berne Daiichi Sankyo Co Ltd, Daiichi Sankyo Europe GmbH Switzerland 2020-10-01 2021-12-31 CONVINCE, CONVINCE VERSION 1.0 12052020, NCT04516941 Phase 3 Clinical Not yet recruiting 2 15 Months 420 Olga Deckarm, MD, Stephan Windecker, Stephan Windecker, MD, Stephan Windecker, Prof. Dr. 2020-08-21
CPCP: Convalescent Plasma for COVID-19 Patients Coronavirus disease 19 infection convalescent COVID-19 plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Vinmec Research Institute of Stem Cell and Gene Technology National Institute for Infectious And Tropical Diseases, National Institute of Hematology and Blood Transfusion, Vietnam, National Institute of Hygiene and Epidemiology, Vietnam Vietnam 2020-08-01 2020-12-30 CPCP, ISC.20.11, ISC.20.11.1, NCT04516954 Phase 0 Clinical Recruiting 1 4 Months 10 2020-08-21
Hyperbaric oxygen therapy for hospitalized patients with COVID-19 Coronavirus disease 19 infection hyperbaric oxygen therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Federal University of Juiz de Fora (UFJF), Universidade Federal de Minas Gerais Hospital e Maternidade Therezinha de Jesus Brazil 2020-08-18 31831420.9.1001.5149, 4.137.642, RBR-2fvjjm, U1111-1253-2793 Phase Not Applicable Not yet recruiting 1 40 Daniel Baumfeld, José da Mota Neto, Rafael Zambelli Pinto 2020-08-21
APC Trial: Randomized, study to evaluate early prone position in patients with COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome prone position alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Brasília Brazil 2020-08-30 33576620.9.1001.5455, 4.151.555, APC Trial, RBR-2k66ft, U1111-1253-7949 Phase Not Applicable Not yet recruiting 1 200 Rodrigo Santos Biondi 2020-08-31
HSD3B1 Gene Polymorphisms With Outcomes in SARS-CoV-2 Infected Patients Coronavirus disease 19 infection RNA sampling alone, Sanger sequencing alone, formalin-fixed paraffin embedded tissue blocks alone, polymerase chain reaction alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Oncology Institute of Southern Switzerland Institute of Oncology Research (Switzerland), Istituto Cantonale di Patologia Switzerland 2020-09-01 2021-08-31 COVID19-GENEEXP, NCT04516850 Phase Not Applicable Not yet recruiting 2 12 Months 500 Christian Garzoni, MD, Ricardo Pereira Mestre, Ricardo Pereira Mestre, MD 2020-08-28
ELABORATE-19: Eltrombopag Plus rhTPO Versus Eltrombopag for ITP During the COVID-19 Pandemic Coronavirus disease 19 infection, Immune thrombocytopenic purpura eltrombopag plus recombinant human thrombopoietin (sc, idiopathic thrombocytopenic purpura/thrombocytopenia/aplastic anemia), 3SBio Thrombopoietin receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) People's Hospital Peking University China 2020-08-31 2022-08-31 ELABORATE-19, ITP-PKU020, NCT04516837 Phase 2 Clinical Recruiting 1 24 Months 120 Xiaohui Zhang, Xiaohui Zhang, MD, Xuelin Dou, MD 2020-09-06
Therapeutic Use of Convalescent Plasma in the Treatment of Patients With Moderate to Severe COVID-19 Coronavirus disease 19 infection, Viral pneumonia COVID-19 convalescent plasma alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) South African National Blood Service South Africa 2020-09-03 2022-07-31 NCT04516811, PROTECT-PATIENT TRIAL Phase 3 Clinical Not yet recruiting 1 22 Months 600 Cynthia Nyoni, Karin vandenBerg, Dr, Mpumi Maxebengula, BCom, Sean Wasserman, A/Professor 2020-08-21
BVAC19: Blood Volume Assessment in COVID-19 ICU Patients Coronavirus disease 19 infection BVA-100 software package alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) NYU Langone Health US 2020-08-01 2021-02-01 20-00896, BVAC19, NCT04517695 Phase Not Applicable Recruiting 1 6 Months 30 Jan Bakker, MD, PhD 2020-08-20
COVID-TRUST: Impact of Perceived Control on Operational Strain: a Study of COVID-19 Pandemic Caregivers and Military Personnel on Operational Missions Coronavirus disease 19 infection, Psychiatric disorder electrocardiogram alone, electrodermal activity alone, emotional stimulation assessment alone, saliva sampling alone, work-related stress assessment alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Direction Centrale du Service de Sante des Armees France 2020-09-30 2021-02-28 2020-COVID19-28, COVID-TRUST, NCT04517136 Phase Not Applicable Not yet recruiting 1 5 Months 60 Damien CLAVERIE, MD, PhD, Khaldoun KUTEIFAN, MD 2020-08-20
fenix: Evaluation of symptoms, respiratory, pulmonary image and inflammation in patients who have been hospitalized for coronavirus infection in the period of a year, multicentric study Coronavirus disease 19 infection, Inflammatory disease, Respiratory disease Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Hospital Beneficiência Portuguesa de Bauru, Hospital Estadual Américo Brasiliense, Hospital Estadual de Bauru, Hospital Of Syrian Lebanese Itatiba S/C Ltd, Incor - Instituto do Coração do Hospital das Clínicas da FMUSP, Irmandade Santa Casa de Misericordia de Araraquara, Unidade de Pesquisa Clínica - Hospital das Clínicas da Faculdade de Medicina de Botucatu, Universidade Federal De Uberlândia - Ufu, Universidade Federal de Sao Paulo - UNIFESP, University Hospital of the Faculty of Medicine of Ribeirão Preto Brazil 2020-06-02 A27072519840, CAAE:31258820.5.1001.5411, CEP: 4.015.191, CEP: 4.121.653, RBR-8j9kqy, fenix Phase Not Applicable Recruiting 1 270 Andre Luis Pereira Alburquerque, Eloara Vieira Machado Ferreira Alvares, Suzana Erico Tanni Minamoto 2020-08-27
Intramuscular Effect of Polymerized Type I Collagen on the Cytokine Storm in COVID-19 Patients Coronavirus disease 19 infection, Inflammatory disease, Pulmonary fibrosis collagen-polyvinylpyrrolidone alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto Nacional de Ciencias Medicas y Nutricion Mexico 2020-08-19 2021-06-19 IRE-3412-20-21-1, NCT04517162 Phase 1 Clinical Recruiting 1 10 Months 90 Daniel Azamar-Llamas, MD, Diego F Hernández-Ramírez, PhD, Elizabeth Olivares-Martínez, PhD, Enrique Ochoa-Hein, MD, Eric Ochoa-Hein, MD, Gonzalo Torres-Villalobos, MD, PhD, Janette Furuzawa Carballeda, Janette Furuzawa-Carballeda, PhD, Luis A Septien-Stute, MD 2020-09-04
canSEROcov: Study of the Specific Seroprevalence of SARS-CoV-2 in a Sample of Patients and Salaried Staff From a French Anti-cancer Center at the End of the Containment Period of the SARS-CoV-2 Pandemic Cancer, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Georges-François Leclerc France 2020-05-12 2020-06-30 2020-A00877-32, NCT04517097, canSEROcov Phase Not Applicable Completed 1 1 Month 1680 2020-08-21
SeroCovEms: Study of SARS-CoV2 Virus (COVID-19) Seroprevalence Among Lyon-Bron Military Health Schools Personnel Coronavirus disease 19 infection Anti-SARS-CoV2 serology test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Direction Centrale du Service de Sante des Armees France 2020-09-30 2020-11-30 2020-COVID19-29, NCT04516928, SeroCovEms Phase Not Applicable Not yet recruiting 1 2 Months 950 Annick BUZENS, MD, Christophe MARTINAUD, MD, PhD, Ludovic KARKOWSKI, MD 2020-08-22
A phase III trial of WHOOP, a wearable device to check on several daily health data in COVID-19 patients Coronavirus disease 19 infection WHOOP alone G42 Healthcare 2020-07-16 Phase 3 Clinical Recruiting 0 2020-08-21
Clinical study to assess the safety and tolerability of administration, directly into a vein, of human umbilical cord and placental blood plasma (Plasmacord) in patients with Severe acute respiratory syndrome resulting from Sars-Cov-2 infection (fever, cough headache, muscle aches and difficulty breathing) Coronavirus disease 19 infection, Respiratory distress syndrome Plasmacord alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cryopraxis Criobiologia Ltda Brazil 2020-07-20 32622920.5.0000.0070, 4.055.744, 4.122.919, RBR-4pfygr, U1111-1256-0705 Phase 1/Phase 2 Clinical Not yet recruiting 1 10 Dayane Vila Nova, Elie Fiss, Maria Helena Nicola 2020-08-20
Halodine Nasal Antiseptic in Patients With COVID-19 Coronavirus disease 19 infection Povidone-Iodine Solution (Halodine LLC) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Halodine LLC 2020-09-01 2020-12-31 HDN-N02-COV24A, NCT04517188 Phase 4 Clinical Not yet recruiting 0 4 Months 40 Samuel B Barone, MD, Samuel Barone, MD 2020-08-21
A Study of AK-119, Anti-CD73 Antibody, a Treatment for COVID-19, in Healthy Subjects Coronavirus disease 19 infection AK-119 alone CD73 antagonist Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Akesobio Pty Ltd Akeso Biopharma Inc New Zealand 2020-09-30 2021-04-30 AK119-101, NCT04516564 Phase 1 Clinical Not yet recruiting 1 7 Months 32 Kon Yew Kwek 2020-08-21
An observational, retrospective study on the protective role of chronic treatment with direct oral anticoagulants in elderly patients with COVID-19 interstitial pneumonia Atrial fibrillation, Coronavirus disease 19 infection, Deep vein thrombosis, Heart disease, Lung embolism, Pneumonia apixaban alone, dabigatran etexilate mesylate alone, edoxaban alone, rivaroxaban alone Factor IIa antagonist, Factor Xa antagonist, Protease-activated receptor-1 antagonist Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Modena and Reggio Emilia Italy Phase Not Applicable Status not specified 1 70 2020-08-19
A multicenter clinical trial to evaluate 10-min rapid point-of-care saliva-based test for detecting active SARS-CoV-2 infections Coronavirus disease 19 infection rapid point-of-care saliva-based test alone Todos Medical Ltd Israel Phase Not Applicable Recruiting 2 2020-08-19
A phase II/III trials to assess safety and efficacy of Dexaneurosone prophylaxis and treatment for early and moderate cases of Covid-19 Coronavirus disease 19 infection dexaneurosone alone Biomed Industries Inc Phase 2/Phase 3 Clinical Planned 0 2020-08-19
Phase III, Double-blind, Placebo-controlled Study of AZD-1222 for the Prevention of COVID-19 in Adults Coronavirus disease 19 infection AZD-1222 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) AstraZeneca plc Biomedical Advanced Research and Development Authority (BARDA), IQVIA RDS Pty Ltd, US Department of Health and Human Services US 2020-08-17 2022-10-05 D8110C00001, NCT04516746 Phase 3 Clinical Not yet recruiting 68 25 Months 30000 Ann Falsey, MD, AstraZeneca Clinical Study Information Center, Dr. Eric Daar, Dr. Raphael Landovitz, Magda Sobieszczyk, MD 2020-08-28
A phase II/III trials to assess safety and efficacy of Biomedivir prophylaxis and treatment for early and moderate cases of Covid-19 Coronavirus disease 19 infection traneurocin + atazanavir (oral, COVID-19), NeuroActiva alone AMPA receptor modulator, HIV-1 protease inhibitor Biomed Industries Inc Phase 2/Phase 3 Clinical Planned 0 2020-08-24
Experience of Orthopedic and Spine Center Pakistan During COVID-19 Coronavirus disease 19 infection, Infectious arthritis, Injury, Spinal disease AD cage alone, Ilizarov alone, K wiring alone, acetabulum fixation alone, amputation alone, arthroplasty alone, arthroscopic anterior cruciate ligament reconstruction alone, arthrotomy alone, bilateral total hip replacement alone, bilateral total knee replacement alone, biopsy alone, bipolar hemiarthroplasty alone, cannulated screw fixator alone, disc excision alone, dura repair alone, dynamic compression plate alone, dynamic hip screw alone, elbow reconstruction alone, external fixator (AO Foundation) alone, implant removal alone, intramedullary nail alone, knee arthroscopy alone, lateral mass screw fixation alone, locking compression plate alone, meniscectomy alone, pelvic fixation alone, plaster of paris (POP) alone, posterior cervical decompression alone, tension band wiring technique alone, transpedicular screw fixation alone, unilateral total hip replacement alone, unilateral total knee replacement alone, vacuum assisted closure (VAC) dressing alone, wound wash alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ghurki Trust Teaching Hospital Pakistan 2020-03-19 2020-08-15 30, NCT04516824 Phase Not Applicable Completed 1 4 Months 2160 Dr. Ashfaq Jadoon, Dr. Majid Cheema, Dr. Samreen Sadiq, Prof Amer Aziz, Prof Rizwan Akram, Prof. Atiq Uz Zaman, Prof. Ijaz Ahmad 2020-08-20
A phase II/III trials to assess safety and efficacy of Nanomedivir for prophylaxis and treatment for early and moderate cases of Covid-19 Coronavirus disease 19 infection Nanomedivir alone AMPA receptor modulator Biomed Industries Inc Phase 2/Phase 3 Clinical Planned 0 2020-08-19
A phase I single-IV administration ascending dose study to assess the safety and tolerability of HFB-30132A in healthy subjects Coronavirus disease 19 infection HFB-30132A alone Angiotensin converting enzyme 2 inhibitor, COVID19 Spike glycoprotein inhibitor Healthy volunteers accepted HiFiBio US Phase 1 Clinical Planned 1 2020-08-28
A Phase 1a study was to assess safety, tolerability and pharmacokinetics of remdesivir in healthy volunteers Coronavirus disease 19 infection remdesivir (inhalant solution, COVID-19), Gilead alone COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Healthy volunteers accepted Gilead Sciences Inc US Phase 1b Clinical Not yet recruiting 1 60 2020-08-19
A case-report study of acute hemolysis induced by hydroxychloroquine in a patient with severe COVD-19 related lung injury Coronavirus disease 19 infection, Viral pneumonia hydroxychloroquine plus lopinavir + ritonavir HIV protease inhibitor Male, European Ancestry Universita di Verona Phase Not Applicable Status not specified 0 1 2020-08-19
>A clinical trial of Sputnik V for the prevention of Covid-19 in Venezuela Coronavirus disease 19 infection Sputnik V alone COVID19 Spike glycoprotein modulator Venezuelan Institute of Scientific Investigations (IVIIC) Venezuela Phase Not Applicable Planned 1 2020-08-19
COVIDET: Assessment of SARS-CoV-2 Seroprevalence in Detention Coronavirus disease 19 infection venous blood test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-09-01 2021-01-01 APHP200667, COVIDET, NCT04516512 Phase Not Applicable Not yet recruiting 1 4 Months 2500 Anne Dulioust, MD, PhD, Anne Dulioust, MD,PHD, Anne Maie Roque-Afonso, MD, MPH, Guillaume Mellon, MD, MPH, Guillaume Mellon, MD,MPH 2020-08-20
Efficacy of L Plantarum and P Acidilactici in Adults With SARS-CoV-2 and COVID19 Coronavirus disease 19 infection, Dyspnea Variable regimens including Lactobacillus plantarum CECT 7484 , Lactobacillus plantarum CECT 7485 , Lactobacillus plantarum CECT7481 , P acidilactici CECT 7483 Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) AB Biotics Hospital General Dr. Manuel Gea González, Innovacion y Desarrollo de Estrategias en Salud Mexico 2020-08-19 2021-01-31 ABB-COVID19, NCT04517422 Phase Not Applicable Recruiting 0 5 Months 300 Paola Juarez-Valdez, MD, Pedro G Gutierrez-Castrellon, MD, PhD, Pedro Gutierrez-Castrellon, MD, PhD 2020-09-04
Hydroxychloroquine ineffective as a preventive antiviral against COVID-19 patiients with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) Coronavirus disease 19 infection hydroxychloroquine alone Case Western Reserve University Phase Not Applicable Status not specified 0 159 Mendel Singer, PhD, MPH 2020-08-19
An observational, cautionary case report to evaluate the outcomes of tocilizumab therapy in patients with COVID-19-induced cytokine release syndrome Coronavirus disease 19 infection tocilizumab alone University of New Brunswick Phase Not Applicable Status not specified 0 2 2020-08-25
SOBERANA 01: Phase I/II, randomized, controlled, adaptive, double-blind and multicenter study to evaluate the safety, reactogenicity and immunogenicity, of the prophylactic FINLAY-FR-1 anti-SARS-CoV-2 Vaccine Candidate in a two-doses schedule(COVID-19) Coronavirus disease 19 infection FINLAY-FR-1 anti-SARS-CoV-2 Vaccine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Finlay Institute Cuba 2020-08-24 2021-01-11 IFV/COR/04, RPCEC00000332, SOBERANA 01 Phase 1/Phase 2 Clinical Not yet recruiting 1 4 Months 676 Beatriz Paredes Moreno, Meiby Rodríguez Gonzalez, Sonia Perez Rodriguez 2020-08-20
Developing the online program of SST Autism, Coronavirus disease 19 infection Online meeting system alone, Social skills training program alone Children (6-12 yrs) Osaka University Japan 2020-08-15 UMIN000041437 Phase Not Applicable Not yet recruiting 1 100 TOMOKA YAMAMOTO 2020-08-27
Garlic and cinnamon on the treatment of patients with corona Coronavirus disease 19 infection cinnamon essential oil (Zardband pharmaceutical company) alone, garlic essential oil (Amin Pharmaceutical Company) alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sabzevar University of Medical Sciences Iran 2020-08-22 IRCT20200705048011N1, ir.medsab.rec.1399.072 Phase Not Applicable Recruiting 1 45 Dr.Fereshte Ghorat, Nasrin Fazel 2020-08-24
Famotidine and COVID-19 Coronavirus disease 19 infection Variable regimens including atazanavir , atazanavir + ritonavir , chloroquine phosphate , famotidine (Chemidarou Pharmaceutical Company) , hydroxychloroquine sulfate , lopinavir + ritonavir HIV GAG POL polyprotein inhibitor, HIV GAG protein inhibitor, HIV protease inhibitor, HIV-1 protease inhibitor Bandare-abbas University of Medical Sciences Iran 2020-06-21 IR.HUMS.REC.1399.255, IRCT20200509047364N2 Phase 3 Clinical Recruiting 1 20 Dariush Hooshyar, Dr. Mehdi Hassaniazad, Dr. Mitra Kazemijahromi, Dr. Teamur Aghamolaei 2020-08-19
Giloy Gomutra Capsule, Asthi churna aur Kamdhenu Asava ka vaishvik mahamari Covid-19 par logo ka anubhav aur Chikitsakiya prabhava ka Ankalan Coronavirus disease 19 infection Variable regimens including Asthi Churna , Ayurvedic Giloy Gomutra , Kamdhenu Asava Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bansi Gir Gaushala India 2020-08-18 CTRI/2020/08/027083 Phase Not Applicable Not yet recruiting 2 100 Dr Dineshchandra H Pandya, Dr Urvi Pandya 2020-08-19
Effects of chest physiotherapy in COVID-19 patients with respiratory infection Coronavirus disease 19 infection, Respiratory tract infection chest physiotherapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Semnan University of Medical Sciences Iran 2020-09-20 IR.SEMUMS.REC.1399.111, IRCT20160808029264N9 Phase 2/Phase 3 Clinical Not yet recruiting 1 44 Dr Parviz Kokhaei, Dr Rasool Bagheri, Dr. Mohammad Memarian 2020-08-19
Efficacy of N-acetylcysteine in patients with COVID-19 Coronavirus disease 19 infection Variable regimens including N-acetylcysteine , atazanavir + ritonavir , hydroxychloroquine , lopinavir + ritonavir HIV protease inhibitor Iran University of Medical Sciences Iran 2020-05-21 IR.IUMS.REC.1399.206, IRCT20200623047897N1 Phase 3 Clinical No longer recruiting 1 60 Dr. Seyyed Abbas Motevalian, Najmolsadat Atefi, Niloufar Najar Nobari 2020-08-24
COSMIC-19: Investigating the impact of coronavirus infection (COVID-19) on cardiovascular injury using multiple imaging methods Cardiovascular injury, Coronavirus disease 19 infection CT coronary angiogram alone, PET scan alone, cardiac MRI alone, flurodeoxyglucose alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Aga Khan University Hospital United Kingdom Research & Innovation Kenya 2020-03-23 2020/IERC-74, COSMIC-19, ISRCTN12154994 Phase Not Applicable Recruiting 1 50 Dr Anoop Shah, Dr Shirjel Alam 2020-08-19
Home Management of Adult Egyptian Mild COVID-19 Cases Coronavirus disease 19 infection telemedicine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Cairo University Egypt 2020-07-01 2021-03-31 NCT04515199, TELEMEDICINE IN MILD COVID-19 Phase Not Applicable Recruiting 1 9 Months 400 Ibrahim El Ebrashy, Professor, Maha Hossam Al-Din Ibrahim, Professor, Mohamed Tharwat Hegazy, Mohamed Tharwat Hegazy, Lecturer 2020-08-19
UNITY Global: An International Registry of Healthcare Workers to Collect Information on Risk Factors for Developing COVID-19 and the use of preventative therapies Coronavirus disease 19 infection Certara COVID -19 Therapeutics Accelerator Senegal, Kenya, Pakistan, South Africa, Uganda, Zambia, Zimbabwe, Nigeria 2020-08-03 UNITY Global Phase Not Applicable Recruiting 8 10000 Craig Rayner, Roman Casciano 2020-08-18
A Dose-Confirmation Study to Evaluate the Safety, Reactogenicity and Immunogenicity of Vaccine CVnCoV in Healthy Adults Coronavirus disease 19 infection SARS-CoV-2 mRNA vaccine (COVID-19), CureVac alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) CureVac AG 2020-09-08 2021-11-09 CV-NCOV-002, NCT04515147 Phase 2 Clinical Not yet recruiting 0 14 Months 691 Clinical Trial Information 2020-09-05
Perinatal Outcomes and Hematological Parameters in COVID-19 Pregnancies Coronavirus disease 19 infection, Pregnancy disorder Healthy volunteers accepted, Female, Young Adults (18-44 yrs) Ankara City Hospital Bilkent Turkey 2020-03-10 2020-08-10 E1-20-672, NCT04515108 Phase Not Applicable Completed 1 5 Months 108 Esin Merve Erol Koç, MD 2020-08-21
To assess the fear and readiness of medical workers to work in the health care set up in the state of Karnataka during COVID-19 illness after the lock down is over Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Kasturba Medical College, Manipal India 2020-08-18 CTRI/2020/08/027082 Phase Not Applicable Not yet recruiting 1 600 Dr Sadhana N Holla, Prabhleen Kaur Sibal 2020-08-19
Elevated fibrinogen and fibrin degradation product were associated with poor outcome in COVID-19 patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Faculty of Medicine Airlangga University Indonesia 2020-05-05 UMIN000041428 Phase Not Applicable Completed 1 1654 Johannes Nugroho, Maya Ayun 2020-08-26
END CoV-2: Novel Point-of-Care Diagnostic Test for SARS-CoV-2 (COVID-19) Coronavirus disease 19 infection Biospecimen Collection (nasopharyngeal sample) alone, Questionnaire Administration alone Healthy volunteers accepted MD Anderson Cancer Center National Cancer Institute, Rice University US 2020-04-09 2021-04-30 2020-0318, 2020-0318, END CoV-2, NCI-2020-03470, NCT04513990 Phase Not Applicable Recruiting 2 12 Months 1500 Kathleen M Schmeler, Kathleen M. Schmeler 2020-08-20
PENFS COVID-19: Neuromodulation With Percutaneous Electrical Nerve Field Stimulation for Adults With COVID-19 Coronavirus disease 19 infection, Dyspnea, Viral pneumonia Auricular percutaneous neurostimulation alone, Neuro-Stim System (NSS)-2 BRIDGE alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Olive View-UCLA Education and Research Institute US 2020-07-13 2021-07-31 1600899, NCT04514627, PENFS COVID-19 Phase Not Applicable Recruiting 1 12 Months 100 Nader Kamangar, M.D., Rajan Saggar, M.D. 2020-08-20
Safety and efficacy of citrobioShield product in improving immunity in COVID-19 patients via inhalation Coronavirus disease 19 infection CitrobioSheild alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) GERMKILL INDIA India 2020-08-17 CTRI/2020/08/027085 Phase Not Applicable Recruiting 1 20 Dr Himanshu Pophale, Dr R Nagaraja Naidu, Subham Dutta 2020-08-19
SeCoVIHA: COVID-19 Prevalence in HIV-infected Patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopitaux Universitaires de Strasbourg 2020-09-15 2020-09-15 7947, NCT04515225, SeCoVIHA Phase Not Applicable Not yet recruiting 0 500 2020-08-19
Comparision of two barrier devices for placement of tube into trachea(windpipe)in COVID-19 patients Coronavirus disease 19 infection Acrylic box alone, Plastic drape alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gujarat Cancer Society Medical college hospital and research centre India 2020-08-17 CTRI/2020/08/027081 Phase 4 Clinical Not yet recruiting 1 500 Dr Heena Chhanwal 2020-08-19
Melatonin in COVID-19 Coronavirus disease 19 infection, Lung disease hydroxychloroquine sulfate (Amin Pharmaceutical company) plus melatonin (Vana Darou Gostar Pharmaceutical Company) Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bandare-abbas University of Medical Sciences Iran 2020-08-22 IR.HUMS.REC.1399.250, IRCT20200506047323N5 Phase 3 Clinical Recruiting 1 60 Mohammad Fathalipour, Parivash Davoodian, Teamur Aghamolaei 2020-08-24
Evaluation the efficacy of Curcuden 35 in patients with COVID-19 Coronavirus disease 19 infection, Viral pneumonia Curcuden 35 (Alborz Nanomed-Tech Company) alone, national guideline based COVID-19 treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shaheed Beheshti Medical University Alborz Nanomed-Tech Company, Mobtaker Electric Company (METEC) Iran 2020-05-21 IR.SBMU.RETECH.REC.1399.085, IRCT20170128032241N3 Phase 3 Clinical Recruiting 1 20 Maria Tavakoli Ardakani, Maryam Mohajeri, Mehran Azodi, Narges Shakeri, ماریا توکلی اردکانی 2020-08-20
A clinical trial of K-NK-ID101 cell therapy for the potential treatment of COVID-19 Coronavirus disease 19 infection K-NK-ID101 cell therapy alone Kiadis Pharma BV Phase Not Applicable Planned 0 2020-08-18
Evaluate the medicinal effects of both Ayurveda combinations Bio-Immune as Anti-viral and Covalix Vaccoil as alternate to Vaccine of COVID-19 on exposed individuals and Covid19 contact Coronavirus disease 19 infection Bio-Immune powder alone, Covalix Vaccoil liquid alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Leaf BioLab Leaf Research Institute India 2020-08-20 BICV19P, CTRI/2020/08/027084, U1111-1256-7669 Phase Not Applicable Not yet recruiting 2 61000 AMIT DUTTA 2020-08-19
A randomized, double-blind, placebo-controlled pilot clinical study to evaluate ensifentrine delivered via pressurized metered-dose inhaler ("pMDI") formulation as a treatment for patients hospitalized with COVID-19 Coronavirus disease 19 infection ensifentrine (DPI/MDI, respiratory diseases/COVID-19), Verona Pharma alone PDE 3 inhibitor, PDE 4 inhibitor Verona Pharma plc US Phase Not Applicable Planned 1 2020-08-24
Covae: Assessment of the Prevalence and the Impact of the COVID-19 Epidemic in the French Flight Crew in 2020 Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Direction Centrale du Service de Sante des Armees France 2020-09-30 2020-12-31 2020-COVID19-26, Covae, NCT04514874 Phase Not Applicable Not yet recruiting 2 3 Months 500 Marc MONTEIL, MD, Sébastien BISCONTE, MD 2020-08-20
A clinical trial of Sputnik V for the prevention of Coronavirus disease 19 infection Coronavirus disease 19 infection Sputnik V alone COVID19 Spike glycoprotein modulator Instituto De Tecnologia Do Parana of Brazil Russian Direct Investment Fund Phase Not Applicable Planned 0 2020-08-24