Last updated: Oct 15, 2020 - 02:00 BST

Title Indication Intervention Actions PatientSelection Sponsor Collaborator Country StartDate EndDate Identifiers Phase Recruitment Status Sites Trial Duration Enrollment Count Contacts LastChanged
CAMELOT: Camostat Efficacy versus Placebo for Outpatient Treatment of COVID-19 Coronavirus disease 19 infection camostat mesylate alone Serine protease inhibitor, Transmembrane serine protease 2 inhibitor, Trypsin inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sagent Pharmaceuticals Inc US 2020-10-31 2021-01-31 CAMELOT, NCT04583592, NI03-CV19-001 Phase 2 Clinical Not yet recruiting 0 3 Months 300 Atasi Jana, M.D., Brett Foster, Cheryl Hargrove, Erin Kelly, Jackie Duckett, Janet Nuttall, M.P.H., Janett Jalil, Julie Lafave, Niurka Romero, Olia Nayor, Priscilla Hernandez, Rabia Gilani, Yelamis Cartaya, Yeslin Arias 2020-10-13
Mental Imagery to Increase Face Covering Use in UK-based Public Places During the COVID-19 Pandemic Coronavirus disease 19 infection Mental imagery alone, Process imagery alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of East London University of Manchester UK 2020-08-19 2020-12-01 ETH2021-0006, NCT04583449 Phase Not Applicable Recruiting 1 3 Months 250 Dominic Conroy, PhD 2020-10-13
ImmuneSense COVID-19 Study Coronavirus disease 19 infection T-Detect SARS-CoV-2 assay alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Adaptive Biotechnologies Corp Covance Inc US 2020-10-09 2021-01-09 NCT04583982, PRO-00781 Phase Not Applicable Not yet recruiting 1 3 Months 125 Jennifer Dines, MD, Jia Qadeer, Sarah Duffy, Thomas Manley, MD 2020-10-13
TeleCCCAP: Feasibility and Quality of TeleConsultation in Pediatric Anesthesia Anesthesia, Coronavirus disease 19 infection teleconsultation alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Centre Hospitalier Universitaire de Toulouse France 2020-10-07 2022-03-14 2020-A02275-34, NCT04583865, RC31/20/0220, TeleCCCAP Phase Not Applicable No longer recruiting 1 17 Months 400 KERN Delphine, MD 2020-10-13
Evaluation of the Performance of the Covid-19 Ag BSS Rapid Antigenic Test in Symptomatic Children in a Pediatric Emergency Department Coronavirus disease 19 infection Biosynex Covid-19 Ag-BSS test alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Centre Hospitalier Intercommunal Creteil 2020-10-01 2021-01-01 NCT04583189, SPEEDYCOVI Phase Not Applicable Not yet recruiting 0 3 Months 500 Camille JUNG, Ph D 2020-10-13
BET-A: Big Effect Trial (BET-A) for the Treatment of COVID-19 Coronavirus disease 19 infection remdesivir plus risankizumab COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, IL-23 antagonist, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Allergy and Infectious Diseases US 2020-10-30 2021-07-01 20-0013A, BET-A, NCT04583956 Phase 2 Clinical Not yet recruiting 10 8 Months 200 20-0013 Central Contact 2020-10-13
DYSPO: Photoplethysmographic Scaling of Dyspnea Coronavirus disease 19 infection, Dyspnea, Respiratory failure ECG alone, Pulse oximeter alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Institutul de Urgenta pentru Boli Cardiovasculare Prof.Dr. C.C. Iliescu Romania 2020-10-01 2021-07-30 18751, DYSPNOEA - SPO2 CURVE STUDY, DYSPO, NCT04582838 Phase Not Applicable Recruiting 2 9 Months 60 Balan Cosmin, Consultant, Balan Ion Cosmin, Cristian Cobilinschi, Consultant, Serban I Bubenek Turconi, Professor 2020-10-13
Differential Expression of Cytokines, Transcriptome and miRNA in COVID-19 Egyptian's Patients Coronavirus disease 19 infection C-reactive protein test alone, D-dimer test alone, PCR test alone, complete blood count test alone, cytokine profiling alone, differential leukocyte test alone, ferritin test alone, miRNA analysis alone, transcriptome analysis alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tanta University Egypt 2020-10-04 2022-10-03 CTM_COVID-19, NCT04583566 Phase Not Applicable Recruiting 2 24 Months 40 Mohammed Eid, Doctor, Mohammed El Shanshoury, Professor, Mohammed Hanteera, Professor 2020-10-13
KNC19: Knust COVID-19 Clinical Trial Coronavirus disease 19 infection Nibima alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) kwame Nkrumah University of Science and Technology Ghana 2020-12-01 2021-01-29 KNC19, PACTR202010690466874 Phase 2 Clinical Not yet recruiting 1 1 Month 20 Ellis Owusu Dabo, Mohamed Mutocheluh 2020-10-13
Send-In Sample Collection for Comprehensive Analyses of Innate and Adaptive Immune Responses During Acute COVID-19 and Convalescence Coronavirus disease 19 infection Healthy volunteers accepted, Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Allergy and Infectious Diseases National Institutes of Health Clinical Center US 2020-10-15 2025-08-31 000044-I, 10000044, NCT04582903 Phase Not Applicable Recruiting 1 58 Months 500 Helen C Su, M.D., Helen Su, M.D. Ph. D, Sandra M Maxwell, R.N. 2020-10-13
Evaluate the Safety, Tolerability, Pharmacodynamics, Pharmacokinetics, and Immunogenicity of HLX-71 (Recombinant Human Angiotensin-converting Enzyme 2-Fc Fusion Protein for COVID-19) in Healthy Adult Subjects Coronavirus disease 19 infection HLX-71 alone Angiotensin converting enzyme 2 inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hengenix Biotech Inc US 2020-11-30 2021-05-31 HLX71-001US-253460, NCT04583228 Phase 1 Clinical Not yet recruiting 1 6 Months 40 Esther Yoon, MD, Jinyun Bai 2020-10-13
Physical Activity Levels of Hypertensive and Healthy Individuals Under Social Isolation During the COVID-19 Pandemic Coronavirus disease 19 infection, Hypertension Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hacettepe University Turkey 2020-06-01 2021-02-01 GO 20/610, NCT04583345 Phase Not Applicable Recruiting 1 8 Months 32 Beyza Nur Karaduz, MSc, Ebru Calik Kutukcu, PhD, Naciye Vardar Yagli, PhD, S. Lale Tokgozoglu, Professor, Yusuf Ziya Sener, MD 2020-10-13
NICOVID-PREV: Efficacy of Nicotine in Preventing COVID-19 Infection in Caregivers Coronavirus disease 19 infection Nicotine patch (Nicopatchlib) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-10-31 2021-10-31 2020-003722-23, APHP200538, NCT04583410, NICOVID-PREV Phase 3 Clinical Not yet recruiting 2 12 Months 1633 Florence TUBACH, MD, Guylaine LABRO, MD, Raphael GAILLARD, MD, Zahir AMOURA, MD 2020-10-13
AIDED: Acute Kidney Injury in Covid-19 Coronavirus disease 19 infection, Renal injury Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospitals Of Derby and Burton NHS Foundation Trust UK 2020-10-31 2022-09-30 AIDED, NCT04583293, UHDB/2020/076 Phase Not Applicable Not yet recruiting 1 23 Months 220 Maarten W Taal, Professor, Nitin V Kolhe, Doctor 2020-10-13
DISCOVER: The Salivary Raman COVID-19 Fingerprint Coronavirus disease 19 infection Aramis Raman microscope (Horiba Jobin-Yvon) alone, Raman spectroscopy alone, portable Raman spectrometer alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fondazione Don Carlo Gnocchi - Onlus Italy 2020-06-01 2021-06-01 DISCOVER, FDG_SALIVACOVID01, NCT04583306 Phase Not Applicable Recruiting 2 12 Months 120 Cristiano Carlomagno, PhD, Jorge Navarro, MD, Luca C Bianchi, MD, Marzia Bedoni, PhD, Paolo I Banfi, MD 2020-10-13
Evaluation of the efficacy and safety of Atazanavir/Ritonavir plus Hydroxychloroquine regimen in patients with moderate COVID-19 Coronavirus disease 19 infection, Viral pneumonia atazanavir sulfate + ritonavir (HIV infection), Mylan Laboratories plus hydroxychloroquine HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Mazandaran University of Medical Sciences Iran 2020-08-22 IR.MAZUMS.REC.1399.602, IRCT20200328046886N2 Phase 3 Clinical Recruiting 1 120 Hamideh Abbaspour Kasgari, Hamideh Abbaspour kasgari, Research and technology department 2020-10-13
A clinical study of Reveal 35C in the detection of pneumonia (including COVID-19) Coronavirus disease 19 infection, Viral pneumonia Reveal 35C alone KA Imaging Inc Canada Phase Not Applicable Status not specified 1 2020-10-13
Association of calcium channel blocker use with COVID-19 clinical outcome: a metaanalysis Cardiovascular disease, Coronavirus disease 19 infection calcium channel blocker therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitas Airlangga Asia 2020-10-11 UMIN000042076 Phase Not Applicable Recruiting 0 1000 Eka Mulia, Mochamad Yusuf 2020-10-12
Effectiveness of favipiravir in comparison with tenofovir alafenamid in patients with COVID-19 Coronavirus disease 19 infection favipiravir (Nafas farmed Co) alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ardabil University of Medical Sciences Iran 2020-09-20 IR.ARUMS.REC.1399.310, IRCT20150808023559N23 Phase 2 Clinical Recruiting 1 100 Dr Farhad Pourfarzi, Somaieh Matin 2020-10-12
A Global, Phase IIb/III Clinical Trial to Assess the Effect of CV-07050101 in Patients With Coronavirus Disease 19 Infection Coronavirus disease 19 infection SARS-CoV-2 mRNA vaccine (COVID-19), CureVac alone COVID19 Spike glycoprotein modulator CureVac AG 2020-12-31 Phase 2/Phase 3 Clinical Planned 0 30000 2020-10-12
COVID Watch + COVID Pulse Coronavirus disease 19 infection COVID Watch alone, PCORI Pulse alone, automated text-messaging program alone, telemedicine nurse-led care alone, triage protocol alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Pennsylvania 2020-10-21 2021-10-31 844043, NCT04581863 Phase Not Applicable Not yet recruiting 0 12 Months 850 Dina Abdel-Rahman, BS, Jessie Hemmons, MS 2020-10-12
Effect of Beta-interferon and methylprednisolone in COVID-19 Coronavirus disease 19 infection Variable regimens including Keltra , beta-interferon , hydroxychloroquine , methylprednisolone , naproxen Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shahid Sadoughi University of Medical Sciences and Health Services Iran 2020-05-04 IR.SSU.REC.1399.040, IRCT20200825048514N1 Phase 3 Clinical No longer recruiting 1 60 Fatemeh sadat Aghaei meybodi, Masoud Mirzaei 2020-10-12
A Phase I/II Study to Assess the Safety, Tolerability and Pharmacokinetics of NGM-621 in Healthy Subjects, and to Assess the Safety, PK and Efficacy in Subjects With Moderate to Severe ARDS Caused by COVID-19 Adult respiratory distress syndrome, Coronavirus disease 19 infection NGM-621 alone Complement C3 inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) NGM Biopharmaceuticals Inc 2020-10-31 2021-09-30 621-CP-102, NCT04582318 Phase 1/Phase 2 Clinical Not yet recruiting 0 11 Months 48 NGM Study Director 2020-10-12
Effect of Blood Transfusion in COVID-19 Coronavirus disease 19 infection packed cell alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Boushehr University of Medical Sciences Iran 2020-10-11 IR.BPUMS.REC.1399.108, IRCT20201003048904N1 Phase 2 Clinical Recruiting 1 40 Farhad Abbasi, Farhad abbasi, Gholamreza khamisipour, Negar Changizi 2020-10-12
Proportional Open Ventilation (POV) Device and Its Efficacy in Managing Acute Respiratory Failure in COVID-19 Patients Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure Life2000 Ventilator alone, high-flow nasal cannula therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hill-Rom Holdings Inc US 2020-08-28 2020-10-31 CR-RR-2020-004, NCT04581161 Phase Not Applicable Recruiting 1 2 Months 10 Jonathan Shelver, MD, Malia Remackel, Marissa Peterson 2020-10-13
Study to Investigate Long-term Pulmonary and Extrapulmonary Effects of COVID-19 Coronavirus disease 19 infection, Lung disease Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Inselspital, Berne Switzerland 2020-05-01 2023-06-01 2020-00799, NCT04581135 Phase Not Applicable Recruiting 9 37 Months 500 Christian Clarenbach, PD, Christian Garzoni, PD, Christophe von Garnier, Prof., Kurt De Jaegere, Manuela Funke-Chambour, MD, Manuela Funke-Chambour, PD, Marco Mancinetti, MD, Martin Brutsche, Prof., Paola Gasche Soccal, Prof., Pierre-Olivier Bridevaux, Prof., Sebastian R. Ott, PD 2020-10-13
COVID-IYON: Study Examining Data Pertaining to Clinical Outcomes and Organizational Responses to the 2020 SARS-CoV-2 Pandemic Cancer, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cancer Trials Ireland Ireland 2020-04-29 2021-06-30 COVID-IYON, CTRIAL-IE 20-01, NCT04581070 Phase Not Applicable Recruiting 11 14 Months 300 Dr. Andrew Hodgson, Dr. Anne Fortune, Dr. Derville O'Shea, Dr. Ezzat ElHassadi, Dr. Gerard Crotty, Dr. Janusz Krawczyk, Dr. Larry Bacon, Dr. Liam Smyth, Dr. Paula Calvert, Dr. Ruth Clifford, Dr. Ruth Morrell, Dr. Silvie Blazkova, Dr. Sinéad Cuffe, Dr. Siobhan Glavey, Prof. Bryan Hennessy, Prof. Cathy Kelly, Prof. Helen Enright, Prof. Janice Walshe, Prof. Linda Coate, Prof. Roisin Connolly 2020-10-12
An Experiment to Evaluate the Safety of agenT-797 in COVID-19 Patients With Severe Difficulty Breathing Coronavirus disease 19 infection, Respiratory distress syndrome agenT-797 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) AgenTus Therapeutics Inc Agenus Inc US 2020-09-21 2021-10-15 C-1300-01, NCT04582201 Phase 1 Clinical Recruiting 1 12 Months 55 Agenus, Inc. Clinical Trial Information, Koen Van Besien, MD, Koen Van Besien, MD, PhD, Medical Director 2020-10-13
SARS-CoV2_KIDS: SARS-CoV2 Antibodies in Pediatric Patients (COVID-19) Coronavirus disease 19 infection Healthy volunteers accepted, Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) University of Erlangen-Nurnberg Medical School Germany 2020-10-05 2022-05-31 405_20 BC, NCT04581148, SARS-CoV2_KIDS Phase Not Applicable Not yet recruiting 1 19 Months 2000 Adrian Regensburger, MD, Antje Neubert, PhD 2020-10-13
An Online-platform to Improve Patient-centered Care During the COVID-19 Pandemic: a GIMEMA Surveillance Program in Hematological Malignancies Coronavirus disease 19 infection, Hematological neoplasm IMEMA-ALLIANCE Platform online monitoring system alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gruppo Italiano Malattie EMatologiche dell'Adulto 2020-10-31 2024-10-31 GIMEMA-ALLIANCE PLATFORM, NCT04581187 Phase Not Applicable Not yet recruiting 0 48 Months 400 2020-10-13
Impact of the COVID-19 pandemic on graduating dental interns: A student’s perspective Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs) Manipal College of Dental Sciences India 2020-10-21 CTRI/2020/10/028296 Phase Not Applicable Not yet recruiting 1 400 Dr Mathangi Kumar 2020-10-13
COSMIC-19: Continuous Signs Monitoring In Covid-19 Patients Coronavirus disease 19 infection Isansys Patient Status Engine alone, continuous vital sign monitoring alone, machine learning artificial intelligence technology alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The Christie NHS Foundation Trust Aptus Clinical Ltd, Manchester University NHS Foundation Trust, Zenzium Ltd UK 2020-07-11 2021-02-01 CFTSP187, COSMIC-19, NCT04581031 Phase Not Applicable Recruiting 2 6 Months 60 Anthony Wilson, Fiona Thistlethwaite, Fiona Thistlethwaite, MB BChir PhD 2020-10-12
Analysis of the SARS-CoV-2 specific immune response in persons with SARS-CoV-2 infection (COVID-19) Coronavirus disease 19 infection Healthy volunteers accepted University of Homburg Bethanien Krankenhaus gGmbH, Universitat des Saarlandes Germany 2020-10-15 76/20, DRKS00023086 Phase Not Applicable Not yet recruiting 2 190 Martina Sester, Simon Herkenrath 2020-10-13
Clinical Trial For SARS-CoV-2 Vaccine (COVID-19) Coronavirus disease 19 infection CoronaVac alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Sinovac Biotech Ltd Turkey 2020-09-14 2021-04-15 9026-ASI, NCT04582344 Phase 3 Clinical Recruiting 24 7 Months 13000 Ali Mert, Prof., Alpay Azap, Prof., Assoc. Prof., Aydın Yılmaz, Prof., Emin Halis Akalın, Prof., Fatma Şebnem Erdinç, Prof., Gülgün Dilek Arman, Prof., Gürdal Yılmaz, Prof., Hatice Rahmet Güner, Prof., Hüsnü Pullukçu, Prof., Murat Akova, Prof., Murat Akova, Professor, Mustafa Kemal Çelen, Prof., Sedat Altın, Prof., Serap Şimşek Yavuz, Prof., Serhat Ünal, Prof., Sıla Akhan, Prof., Taner Yıldırmak, Assoc. Prof., Taner Yıldırmak, Prof., Volkan Korten, Prof., Yaşar Bayındır, Prof., Yeşim Taşova, Prof., Ömer Fehmi Tabak, Prof., Özgür Batum, Specialist, İftihar Köksal, Prof., İlhami Çelik, Prof., İlkay Karaoğlan, Prof., Şükran Köse, Prof. 2020-10-13
Validation of Laboratory Techniques, Strategies, and Types of Samples for Epidemiological Control in the Covid-19 Pandemic Coronavirus disease 19 infection LAMP technique alone, Pool LAMP alone, Pool RT-PCR alone, RT-PCR alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) CUNY Hunter College Bolivia 2020-10-08 2020-11-30 NCT04581083, PROY - UAJMS001/2020 Phase Not Applicable Recruiting 1 1 Month 30 Carmen Amanda Delagadillo Delgadillo, MD, Jimena Martinez, MD, Jorge Tejerina, Lic., Kenji Shoji, PhD, Lucia Alvarado Arnez, PhD, Paloma Rojas Saunero, MD, MSc, Rodrigo Arce Cardozo, Rodrigo Arce Cardozo, MD, MPH, Rodrigo Arce Cardozo, MD,MPH, Roxana Valdez Zamorano, Wilson Muriel Argollo, MD 2020-10-13
PHRUCov01: A Phase II and III Trial of Triazavirin (TZV) for the Treatment of Mild to moderate COVID-19 Coronavirus disease 19 infection standard of care treatment alone, triazavirin alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Wits Health Consortium (Pty) Ltd Perinatal HIV Research Unit, University of the Witswatersrand South Africa 2020-09-08 2021-12-31 NCT04581915, PHRU COV01, PHRUCov01 Phase 2/Phase 3 Clinical Recruiting 1 15 Months 420 Fatima Mayat, Firdaus Nabeemeeah, MBBCh, Neil A Martinson, MBChB, Tumelo Moloantoa, MBChB 2020-10-13
A phase III, global. non-contact trial to assess CoronaVac in healthcare workers in Dhaka, Bangladesh Coronavirus disease 19 infection CoronaVac alone LSK Global Pharma Services Co Ltd Bangladesh Phase 3 Clinical Planned 1 4200 2020-10-12
CLASSIC: Perceptions of the Clinical and Psychosocial Impact of Covid-19 in Patients With Neuromuscular and Neurological Disorders Coronavirus disease 19 infection, Duchenne dystrophy, Neurological disease, Neuromuscular disease, Spinal muscular atrophy Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Royal Brompton & Harefield NHS Trust UK 2020-09-11 2020-12-17 286495, CLASSIC, NCT04581577 Phase Not Applicable Recruiting 1 3 Months 75 Anita K Simonds, MD MBBS, Anita Simonds, MBBS, Kinesh Patel, PhD, Lydia A Spurr, MBBS BMedSci, Lydia Spurr, MBBS, Martin R Cowie, MD MSc, Mary Morrell, PhD 2020-10-13
Oscillation and Lung Expansion Therapy in Patients With COVID-19 Coronavirus disease 19 infection MetaNeb System alone, oscillation and lung expansion (OLE) therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hill-Rom Holdings Inc Emory University, Northwestern University US 2020-09-28 2021-01-01 CR-RR-2020-002, NCT04582214 Phase Not Applicable Recruiting 2 3 Months 30 Brian Becker, RT, Colin Swenson, MD, Elizabeth Cox, Lindsay Downing, MPH, Lisa Wolfe, MD, Phill Cooper 2020-10-13
Coro-Buddy: Prevalence of Antibodies Against SARS-CoV-2 in Tubingen Children Coronavirus disease 19 infection Diagnostic test alone Healthy volunteers accepted, Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) University Hospital Tubingen Germany 2020-07-02 2021-12-31 CORO-BUDDY, Coro-Buddy, NCT04581889 Phase Not Applicable Recruiting 1 17 Months 2380 Andrea Kreidenweiss, Dr., Jana Held, Dr, Jana Held, Dr., Rolf Fendel, Dr., Yudi Tatiana Röckl-Pinilla, Dr. 2020-10-12
PK and Safety of Remdesivir for Treatment of COVID-19 in Pregnant and Non-Pregnant Women in the US Coronavirus disease 19 infection remdesivir alone COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) International Maternal Pediatric Adolescent AIDS Clinical Trials Group Puerto Rico, US 2020-10-15 2022-01-15 DAIDS STUDY ID 38746, IMPAACT 2032, NCT04582266 Phase Not Applicable Not yet recruiting 17 15 Months 40 Adriana Drada, FMD, CCRP, Aleisha Collinson-Streng, RN, BSN, Alice Stek, MD, Allison Agwu, MD, Barsha Chakraborty, BS, Brookie Best, PharmD, MAS, Christy Beneri, DO, Debra McLaud, RN, Diana Clarke, PharmD, Elizabeth Greene, MPH, Ellen Chadwick, MD, Ellen Cooper, MD, MPH, Gwendolyn Scott, MD, Irma L. Febo Rodriguez, M.D., Jaime Deville, MD, Katherine Knapp, MD, Kathleen George, MPH, LaTeshia Thomas-Seaton, Lourdes Topete, RN, Margaret Sanders, MPH, Mariam Aziz, MD, Mark Mirochnick, MD, Martina Badell, MD, Mary Paul, MD, Maureen McNichols, MSN, CCRP, Megan Loughran, Michele Carter, BS, RN, Mobeen Rathore, MD, Nina Sublette, PhD, APRN-BC, Ruth E. Santos, RN, MPH, BSN, Saniyyah Mahmoudi, ARNP, Shelley Buschur, RN, CNM, Stephen Spector, MD 2020-10-12
MEDyMAP: Mapping COVID-19 Spread in a Tertiary Hospital Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital General Universitario de Valencia University of Valencia Spain 2020-10-02 2021-06-15 COVID19-MAPA, MEDyMAP, NCT04581096 Phase Not Applicable Recruiting 1 8 Months 3000 Adina Iftimi, PhD, Carolina Romero García, PhD, Carolina S Romero Garcia, PhD, Carolina Soledad Romero Garcia 2020-10-13
A phase II clinical trial of CYP-001 for the treatment of respiratory distress associated with COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome mesenchymoangioblast-derived mesenchymal stem cell therapy (Cymerus, critical limb ischemia/graft versus host disease/asthma/diabetic foot ulcer), Cynata/FUJIFILM alone Cynata Therapeutics Ltd Phase 2 Clinical Planned 0 2020-10-12
Patients Reactions Towards Their Diagnosis as Having COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) ClinAmygate Egypt 2020-10-10 2020-11-15 NCT04581928, PR0020 Phase Not Applicable Not yet recruiting 1 1 Month 300 Emad R Issak, MD 2020-10-13
Impact of COVID-19 on Psoriasis Practice Coronavirus disease 19 infection, Psoriasis Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cairo University Egypt 2020-09-17 2020-10-31 KAPU2020 10, NCT04581044 Phase Not Applicable Recruiting 1 1 Month 150 Asmaa Abdelnaby, MD, Mohamed HM EL-Komy, MD, Mona El-Kalioby, MD 2020-10-13
A pivotal, randomized, double-blind study to evaluate CPI-006 in hospitalized COVID-19 patients Coronavirus disease 19 infection CPI-006 alone CD73 antagonist Corvus Pharmaceuticals Inc Phase Not Applicable Planned 0 2020-10-12
Evaluation of the effectiveness of intravenous infusion of human COVID-19 hyperimmune plasma with specific antibody titer in hospitalized patients with Covid-19: a randomized clinical trial Coronavirus disease 19 infection, Viral pneumonia human COVID-19 hyperimmune plasma alone, human COVID-19 hyperimmune plasma with antibody titer alone, routine treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tehran University of Medical Sciences Iran 2020-10-11 IR.TUMS.MEDICINE.REC.1399.436, IRCT20201004048922N1 Phase 3 Clinical Recruiting 1 75 Hamidreza Abtahi, Mohammadali Sahraeiyan, Mohammadreza Salehi, Parisa Kianpour 2020-10-13
Study of resistance to COVID-19 of medical staff (Pilot Study) Acute stress disorder, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Japanese Ministry of Health, Labor and Welfare Japan 2020-09-25 UMIN000042061 Phase Not Applicable Not yet recruiting 1 165 Hirayasu Kai, Kunihiro Yamagata 2020-10-12
Perception Of Dentists On Infection Control Measures During Novel Corona Virus (COVID-19) Pandemic Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Manipal College of Dental Sciences India 2020-10-25 CTRI/2020/10/028295 Phase Not Applicable Not yet recruiting 1 400 Dr Neetha Shenoy 2020-10-13
CoTroxCov Study: Cotrimoxazole in hospitalised patients with moderate to early-severe COVID-19 infection Coronavirus disease 19 infection cotrimoxazole alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ministry of Health and Family Welfare India 2020-10-26 CTRI/2020/10/028297, CoTroxCov Study, U1111-1259-2654 Phase 2 Clinical Not yet recruiting 1 200 Dr Santanu Kumar Tripathi 2020-10-13
COVID-19, Prediction Model, Prognosis Coronavirus disease 19 infection prediction model alone Hospital Sungai Buloh Malaysia 2020-10-15 2022-09-15 56523, NMRR-20-2149-56523 Phase Not Applicable Status not specified 1 23 Months 1500 DR THARMINI A/P RAVI, Dr Sharifah Khairul Atikah 2020-10-13
COVIDstroke: Effect of COVID-19 pandemic on stroke admission trend in Malaysia Coronavirus disease 19 infection, Stroke Sultanah Nur Zahirah Hospital Malaysia 2020-11-01 2021-03-31 1, 56595, COVIDstroke, NMRR-20-2148-56595 Phase Not Applicable Not yet recruiting 1 5 Months Mrs NORSIMA NAZIFAH SIDEK 2020-10-13
PoCoPoHo: Post COVID-19 Infection: Impact of Clinical Severity and Timeline on Functional Status, Symptomology and Serological Status Post-Hospitalization Coronavirus disease 19 infection Hospital Raja Permaisuri Bainun Malaysia 2020-10-01 2020-10-31 NMRR-20-2125-56457, PoCoPoHo Phase Not Applicable Status not specified 1 1 Month MOH CHENG KEAT 2020-10-13
Antibiotic-COVID-19 Coronavirus disease 19 infection antibiotics alone Hospital Raja Permaisuri Bainun Malaysia 2020-10-12 2020-11-17 56531, NMRR-20-2124-56531 Phase Not Applicable Status not specified 1 1 Month Dr Izzati Nadhirah Bt Mohamad 2020-10-13
Intranasal administration of recombinant human interferon alfa-2b as prophylaxis of SARS-CoV-2 infection. (COVID-19) Coronavirus disease 19 infection nasalferon alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Center for Genetic Engineering and Biotechnology Cuba 2020-10-12 2020-11-06 IG / IAGN / VS / 2001, RPCEC00000337 Phase 1/Phase 2 Clinical Not yet recruiting 1 80 Francisco Hernandez Bernal, Leader Josué Diaz 2020-10-13
A prospective study of CoVerity in the diagnosis of severe respiratory failure risk in patients with PCR-confirmed SARS-CoV-2 pneumonia Coronavirus disease 19 infection CoVerity COVID-19 Severity Test alone Inflammatix Inc Greece Phase Not Applicable Status not specified 1 97 2020-10-12
Understanding Immunity to the Flu Vaccine in COVID-19 Patients Coronavirus disease 19 infection flu vaccine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Stanford University National Institute of Allergy and Infectious Diseases US 2020-12-01 2022-12-01 5U19AI057229-17, IRB-58356, NCT04579588 Phase Not Applicable Not yet recruiting 1 24 Months 80 Hena Din, Kari Nadeau, MD, PhD 2020-10-12
Fostamatinib for Hospitalized Adults With COVID-19 Coronavirus disease 19 infection fostamatinib disodium alone, standard of care alone Syk tyrosine kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Heart Lung and Blood Institute National Institutes of Health Clinical Center US 2020-10-08 2020-12-15 000110-H, 10000110, NCT04579393 Phase 2 Clinical Recruiting 2 2 Months 60 Edwinia Battle, Jeffrey R Strich, M.D., Jennifer J Kyte, D.N.P. 2020-10-13
EPID CLUSTER: Study of COVID-19 Clusters in Pahang Coronavirus disease 19 infection Jabatan Kesihatan Negeri Pahang Malaysia 2020-10-06 2020-10-21 55739, EPID CLUSTER, NMRR-20-2162-55739 Phase Not Applicable Status not specified 1 Dr WAN ABDUL RAHIM B WAN MUHAMMAD 2020-10-12
SeCuRE Study: Social isolation, depression, anxiety and resilience among older adults in Klang Valley during the COVID-19 crisis Anxiety disorder, Coronavirus disease 19 infection, Depression Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Selayang Hospital Malaysia 2020-11-02 2022-01-03 55538, NMRR-20-2169-55538, SeCuRE Study Phase Not Applicable Not yet recruiting 2 14 Months Dr Zanariah Mat Saher, Dr. Nor Jannah Nasution Raduan 2020-10-12
CORONAVIT: Trial of Vitamin D to Reduce Risk and Severity of COVID-19 and Other Acute Respiratory Infections Coronavirus disease 19 infection, Respiratory tract infection vitamin D alone Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Queen Mary University of London Barts Charity, Pharma Nord ApS UK 2020-10-19 2021-06-30 289515, CORONAVIT, NCT04579640 Phase 3 Clinical Not yet recruiting 1 8 Months 5440 Adrian R Martineau, MD PhD, David A Jolliffe, PhD 2020-10-12
Assessment of COVID-19 in Tearfilm Coronavirus disease 19 infection biological sampling alone, biopsy alone, fluorescein angiography alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Vanderbilt University Medical Center US US 2020-10-09 2021-05-09 201127, NCT04579458 Phase Not Applicable Recruiting 1 7 Months 500 Sapna Gangaputra 2020-10-13
Repeat Testing for SARS-CoV-2 Coronavirus disease 19 infection RT-LAMP Assay alone, Saliva assay test alone Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Wisconsin-Madison National Institutes of Health US 2020-09-29 2021-09-30 2020-1142, 5P51OD011106-59, A536300, NCT04579549, PROTOCOL VERSION 8/17/2020, SMPH/PATHOL-LAB MED/ANAT PATH Phase Not Applicable Recruiting 1 12 Months 10000 David O'Connor, PhD, Kristi L Hall 2020-10-13
Study on use of Homoeopathy Medicines in Treatment of Covid 19 cases Coronavirus disease 19 infection Homoeopathy medicine alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Ministry of Ayush India 2020-10-10 CTRI/2020/10/028233 Phase Not Applicable Not yet recruiting 1 60 Dr SUGATHAN N V 2020-10-13
REMPAR-EHPAD: Managerial and Environmental Risk in French Long-Term Care Institutions Coronavirus disease 19 infection Rennes University Hospital France 2020-06-15 2020-09-01 35RC20_8898_REMPAR-EHPAD, NCT04579289, REMPAR-EHPAD Phase Not Applicable Completed 1 2 Months 230 Aline MD CORVOL 2020-10-12
COVITRA: Prevalence and Outcome of SARS-CoV-2 Infection and COVID-19 in Transplant Recipients Coronavirus disease 19 infection, Hematopoietic stem cell transplantation, Organ transplantation SARS-CoV-2 IgG test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitaire Ziekenhuizen Leuven Jessa Hospital, Katholieke Universiteit Leuven, Universiteit Hasselt, Ziekenhuis Oost-Limburg Belgium 2020-07-01 2021-12-31 COVITRA, NCT04579471, S64036 Phase Not Applicable Recruiting 1 18 Months 2000 Jef Verbeek, MD, Jef Verbeek, MD, PhD, Natalie Van den Ende, Natalie Vandenende 2020-10-12
Psychological effect of coronavirus disease 2019 on pregnant women Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs) All India Institute of Medical Sciences India 2020-10-14 CTRI/2020/10/028232 Phase Not Applicable Not yet recruiting 1 25 Dr Poonam Kumari 2020-10-12
Proof of Concept Study of Ketoji (Liquid) for its Effectiveness in Treatment and Management of COVID-19 Patients Coronavirus disease 19 infection Ketoji alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ruby Hall Clinic India 2020-10-12 BPLS/KTJ/2020, CTRI/2020/10/028231 Phase 2 Clinical Not yet recruiting 1 15 Dr Kapil G Zirpe, Ms Pranjal Ausekar 2020-10-13
Clinical trial of Pippali Rasayana and Nagaradi Kashaya Ghana Vati combination as an adjuvant treatment with ICMR guided medicines in Covid-19 positive mildly symptomatic cases Coronavirus disease 19 infection  ICMR directed therapy alone, Variable regimens including Nagaradi Kashaya Ghana Vati , Pippali Rasayana , Rasayana Kala , Vyanodana Kala Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) PAED'S Ayurved Rugnalaya and Sterling Multispeciality Hospital India CTRI/2020/10/028230 Phase 2 Clinical Not yet recruiting 1 60 Dr Medha Mahesh Joshi, DrYogita Abhijit Jamdade 2020-10-12
Corticosteroids in COVID-19 Coronavirus disease 19 infection, Viral pneumonia dexamethasone alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tehran University of Medical Sciences Iran 2020-09-26 IR.TUMS.MEDICINE.REC.1399.430, IRCT20100228003449N31 Phase 2/Phase 3 Clinical Recruiting 1 119 Hossein Khalili, Mohammad Ali Sahraian 2020-10-12
FACIAL HAIR: Facial Hair, PPE and COVID-19 Coronavirus disease 19 infection Healthy volunteers accepted Royal Cornwall Hospitals Trust UK 2020-05-14 2020-06-08 283609, FACIAL HAIR, NCT04579627 Phase Not Applicable Completed 1 358 2020-10-12
RECEDE: Regional COVID Epidemiology in England Coronavirus disease 19 infection, Renal injury Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospitals Of Derby and Burton NHS Foundation Trust UK 2020-11-01 2021-10-31 NCT04579562, RECEDE, UHDB/2020/075 Phase Not Applicable Not yet recruiting 1 12 Months 5000 Nitin V Kolhe, DM 2020-10-13
A study to know whether investigators can supervise cancer patients infected with COVID-19 from without admission in hospitals. Investigators will test how much helpful is a software called Datos health along with pulse oximeter and thermometer in this supervision by doctors Coronavirus disease 19 infection Datos Platform alone, pulse oximeter alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tata Memorial Hospital India 2020-10-13 CTRI/2020/10/028256 Phase Not Applicable Not yet recruiting 1 30 Dr Manju Sengar 2020-10-12
Psychological Impacts Of The COVID-19 Pandemic On Medical Students In India: A Web-Based Cross-Sectional Study Coronavirus disease 19 infection Young Adults (18-44 yrs) Sri Ramachandra Institute of Higher Education and Research India 2020-10-10 CTRI/2020/10/028257 Phase Not Applicable Not yet recruiting 1 500 Dr S Natarajan, Ria Tyagi 2020-10-12
Feasibility study of a mobile device for the prevention of sepsis in patients with solid tumors after chemotherapy and patients with infectiose diseases (COVID-19) Coronavirus disease 19 infection, Respiratory tract infection, Sepsis VitalPatch alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitätsklinikum Frankfurt Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie Germany 2019-08-02 DRKS00017593, FF136/2018 Phase Not Applicable Recruiting 1 50 Mate Knabe 2020-10-12
CAMMS: Inhibiting transmission of respiratory viruses Coronavirus disease 19 infection nutraceuticals alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) India 2020-11-01 CAMMS, CTRI/2020/10/028255 Phase 2 Clinical Not yet recruiting 2 200 Dr Suman Kapur, Dr Vibhor Tak 2020-10-12
PregCOVID: Retrospective Study of Pregnancy with COVID-19 Coronavirus disease 19 infection Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Dr TMA Pai Hospital India 2020-10-08 CTRI/2020/10/028254, PregCOVID Phase Not Applicable Not yet recruiting 1 44 Shashikala Bhat 2020-10-12
Correlation Between Thoracic Ultrasound and Thorax Computed Tomography Scores Coronavirus disease 19 infection, Viral pneumonia lung ultrasound (LUS) alone, thorax computed tomography (CT) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gaziosmanpasa Taksim Research and Education Hospital Turkey 2020-06-05 2020-09-05 AYŞEV, NCT04577235 Phase Not Applicable Completed 1 3 Months 29 Ayşe Vahapoglu, M.D 2020-10-12
Effect of CBT Intervention to Improve Sleep on Wellbeing, Dietary Intake and Food Preference Coronavirus disease 19 infection, Insomnia cognitive behavioral therapy alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Glasgow UK 2020-10-05 2021-06-01 200190177, NCT04576260 Phase Not Applicable Not yet recruiting 2 7 Months 40 Ayan Merchant, MSc, Ayan Merchant, MSc., Cindy Gray, PhD, Jason Gill, PhD, Stuart Gray, PhD 2020-10-13
An observational, single-center, cohort study to evaluate the association between treatment with colchicine and improved survival of adult hospitalized patients with COVID-19 pneumonia and acute respiratory distress syndrome Coronavirus disease 19 infection, Respiratory distress syndrome colchicine alone, dexamethasone alone, hydroxychloroquine alone, lopinavir + ritonavir alone, standard of care alone, Variable regimens including dexamethasone , hydroxychloroquine , lopinavir + ritonavir HIV protease inhibitor Italy Phase Not Applicable Status not specified 1 262 2020-10-12
Q-TIP: Comparison between certified swab systems (Copan eSwab) and commercially available cotton swabs ('Q-Tip') for the detection of multi-resistant pathogens (MRE) using rectal swabs Coronavirus disease 19 infection, Infectious disease Ebelin Q-Tip cotton swab alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) UniversitätsKlinikum Leipzig Germany 2020-09-20 327/20-ek, DRKS00023249, Q-TIP Phase Not Applicable Recruiting 1 600 Johannes Wiegand 2020-10-13
Corona CPR: Impact of personal protective equipment (PPE) during a simulated cardiac arrest in times of the COVID-19 pandemic Cardiac arrest, Coronavirus disease 19 infection FFP2 personal protective equipment use alone, simulated resuscitation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Arbeitsgemeinschaft Intensivmedizin e.V Germany 2020-09-20 2020-602-f-S, Corona CPR, DRKS00023184 Phase Not Applicable Recruiting 1 400 Stephan Marsch, Timur Sellmann 2020-10-12
Effect of spiritual care based on Ghalbe Salim on anxiety related to COVID-19 (corona phobia) Anxiety disorder, Coronavirus disease 19 infection, Phobia Ghalbe Salim model based spiritual program alone Female Iran 2020-05-23 2020-07-31 IR.LARUMS.REC.1399.001, IRCT20201003048905N1 Phase Not Applicable Completed 1 2 Months 14 Dr Behzad Rezaie, Zohreh Faramarzian 2020-10-09
Randomized, phase II clinical trial to evaluate safety and efficacy of the use of plasma from convalescent patients with the new coronavirus disease (COVID-19) for the experimental treatment of patients hospitalized in the centro medico naval 'cirujano mayor santiago tavara' Coronavirus disease 19 infection convalescent plasma alone, standard hospital treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Peru 2020-09-07 CEMENA-20-01 Phase 2 Clinical Not yet recruiting 1 100 César José Suárez De Armero, José Martín Avilés Calderón, MARIO ORTIZ MONDRAGÓN, Max Grogl 2020-10-09
SALICOV: Evaluation of a Screening Program for SARS-CoV-2 Infection in the General Population Based on the Use of New Detection Approaches or for Diagnostic Orientation on Saliva Coronavirus disease 19 infection saliva sampling alone Assistance Publique Hopitaux de Paris France 2020-10-31 2021-06-30 2020-A02431-38, APHP200960, NCT04578509, SALICOV Phase Not Applicable Not yet recruiting 1 8 Months 2750 Jérôme Le Goff, Professor, LE GOFF Jérôme, Professor, Laure Choupeaux, Master, Solen Kernéis, Doctor, Solen Kernéis, MD, PhD 2020-10-12
SOGUGCOVID: Description of the Population With Genitourinary Tumors and COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Spanish Oncology Genito-Urinary Group Spain 2020-09-30 2021-10-31 NCT04578132, SOG-INM-2020-04, SOGUGCOVID Phase Not Applicable No longer recruiting 32 13 Months 250 Aránzazu González del Alba, M.D., Ph.D., Javier Puente, M.D., Ph.D., Miguel Ángel Climent, M.D., Ph.D., Natalia Vidal, M.D., Ph.D., Sergio Vázquez Estevez, M.D., Ph.D. 2020-10-12
TMPRSS2: Efficacy of Aerosol Combination Therapy of 13 Cis Retinoic Acid and Captopril for Treating Covid-19 Patients Via Indirect Inhibition of Transmembrane Protease, Serine 2 Coronavirus disease 19 infection 13 cis retinoic acid plus captopril ACE inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kafrelsheikh University Egypt 2020-11-30 2021-01-31 NCT04578236, SARS, TMPRSS2 Phase 2 Clinical Not yet recruiting 1 2 Months 360 Mahmoud Elkazzaz, B.Sc,M.Sc in Biochemistry 2020-10-12
A phase I clinical trial for inactivated SARS-CoV-2 Vaccine(Vero Cells) Coronavirus disease 19 infection Vero Cells alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Jiangsu Province Centers for Disease Control and Prevention China 2020-10-07 2022-04-06 ChiCTR2000038804 Phase 1 Clinical Not yet recruiting 2 18 Months 180 Li Guifan, Pan Hongxing 2020-10-09
A clinical trial to test the effectiveness of thalidomide in reducing immune dysfunction in covid-19 disease Autoimmune disease, Coronavirus disease 19 infection thalidomide, Celgene alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ruby Hall Clinic India 2020-10-10 CTRI/2020/10/028253 Phase 2 Clinical Not yet recruiting 1 20 Dr Abhijit R Lodha 2020-10-09
A Study to Evaluate Efficacy of Selected Homoeopathic Medicines in Prevention of COVID-19 Coronavirus disease 19 infection Variable regimens including Arsenic album , Bryonia alba , Camphora Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Ministry of Ayush India 2020-10-15 CTRI/2020/10/028280 Phase Not Applicable Not yet recruiting 1 18000 Dr Meeta Gupta, Dr Raj K Manchanda 2020-10-09
Standard of care with homoeopathy as adjuvant in COVID19 Coronavirus disease 19 infection Homoeopathic medicine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences India 2020-10-12 CTRI/2020/10/028279 Phase Not Applicable Not yet recruiting 1 128 Dr Sushma Bhatnagar 2020-10-09
COVID-19 and children with congenital heart disease Congenital heart defect, Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) All India Institute of Medical Sciences India 2020-10-15 CTRI/2020/10/028251 Phase Not Applicable Not yet recruiting 33 50 Avinash Anantharaj, C S Muthukumaran, Dr Devaprasath, Dr Dharmendra Jain, Dr Gnanasambandan, Dr H ravi Ramamurthy, Dr Harmeet Singh Arora, Dr Jabaraj, Dr Jayashree Mishra, Dr Joseph Xavier, Dr K Sivakumar, Dr Kalyanasundaram, Dr M Jayranganath, Dr Mahesh K, Dr Manoj K Rohit, Dr P V Suresh, Dr Prabhatha Rashmi Murthy, Dr Prashant Mahawar, Dr Prashant Shah, Dr Rema Devi, Dr S Ramakrishnan, Dr Saileela, Dr Sanjay Khatri, Dr Smit Shrivastava, Dr Snehal Kulkarni, Dr Srinivas Lakshmivenkateshiah, Dr Swati Garekar, Edwin Francis, K M Krishnamoorthy, Kavya Mallikarjun, Prabhatha Rashmi Murthy, Rishi Sethi, Suresh Kumar 2020-10-09
The Knowledge, Attitude And Practices related to COVID-19 in Patients Presenting to Glaucoma Clinic and the Reasons for seeking Glaucoma care Coronavirus disease 19 infection, Glaucoma Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Aravind Eye Hospital - Pondicherry India 2020-10-12 CTRI/2020/10/028278 Phase Not Applicable Not yet recruiting 1 246 Dr AnnamalaiO, Dr Kavitha S, Dr Venkatesh R, Kalluri Satya Srividya 2020-10-09
A study to evaluate the effects of stem cells in patients with acute respiratory distress syndrome caused by pneumonia due to COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia Stempeucel alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Indian Council of Medical Research, Ministry of Health and Family Welfare India 2020-10-14 CTRI/2020/10/028250, ICMR/ARDS/20-21/001 Phase 2 Clinical Not yet recruiting 2 40 Dr Geeta Jotwani, Dr Manoj Kumar Panigrahi, Dr Pawan Kumar Gupta, Dr Sharat Damodar 2020-10-09
Effect of N95 mask on general condition and respiration of health care workers Coronavirus disease 19 infection N95 FFRs alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Hamdard Institute of Medical Sciences & Research (HIMSR) India 2020-10-19 CTRI/2020/10/028249 Phase Not Applicable Not yet recruiting 1 30 Sana Yasmin Hussain 2020-10-09
PPI: Stress-free after corona: a psychological help program Acute stress disorder, Coronavirus disease 19 infection, Psychiatric disorder behaviour modification technique based intervention alone, group-based face-to-face intervention alone, home based progressive muscle relaxation exercise alone, home based work sheet exercise alone, low-threshold online digital intervention alone, model deduction intervention alone, parenting strategies based intervention alone, psychoeducation alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Humboldt University of Berlin Germany 2020-09-01 2020-35, DRKS00023220, PPI Phase Not Applicable Recruiting 1 400 Ulrike Luken 2020-10-12
A study to assess the safety and effectiveness of Thymosin alpha-1 (Talpha1) used for the treatment of Moderate to severe COVID 19 Patients Coronavirus disease 19 infection Thymosin alpha alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gufic Bioscience Ltd India 2020-10-12 CTRI/2020/10/028277, GB_THY_001_20 Phase 3 Clinical Not yet recruiting 7 120 Dr Adarsh Shetty, Dr Arti Shah, Dr Dev Nath Jha, Dr Giridhar Patil, Dr Nirhali Sonali Chandrakant, Dr Rahul Ashok Darnule, Dr S K Sonkar, DrPrachee Milind Sathe, Mr Vairamuthu Ammaiyappan 2020-10-09
Chest Radiographic Findings of Adult Patients with Confirmed Coronavirus Disease 2019 (COVID-19) at Southern Philippines Medical Center Coronavirus disease 19 infection Southern Philippines Medical Center Philippines 2020-10-01 2020-12-15 PHRR201001-002988 Phase Not Applicable Recruiting 1 2 Months Maria Theresa T. Sanchez, MD, FPCR, Nalvic De Chavez 2020-10-09
A mHealth-based randomized controlled trial for improving mental health among people living with HIV during the COVID-19 outbreak Coronavirus disease 19 infection, Depression, HIV infection Articles and audios alone, WeChat-based Cognitive-Behavior and Stress Management course alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sun Yat-Sen University China 2020-10-15 2021-12-31 ChiCTR2000038866 Phase 0 Clinical Not yet recruiting 1 14 Months Yan Guo, Yu Zeng 2020-10-09
A Randomized, Double-blind, Placebo-controlled, Phase Ib/II Clinical Study to Evaluate the Preliminary Efficacy, Safety, Pharmacokinetic Profiles and Immunogenecity of JS-016 (Recombinant Human Anti-SARS-CoV-2 Monoclonal Antibody) Given as Intravenous Infusion in Participants with Mild and Moderate COVID-19 or of SARS-CoV-2 Asymptomatic Infection Coronavirus disease 19 infection JS-016 alone COVID19 Spike glycoprotein inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) PAREXEL Clinical Research, Shanghai Junshi Biosciences Co Ltd Ukraine, Philippines, Hong Kong, Russian Federation, China, Singapore 2020-09-30 2021-06-30 2020-CT0565, JS016-002-Ib/II, PHRR201001-002968 Phase 1/Phase 2 Clinical Not yet recruiting 7 9 Months 25 Chriziel Escaño, Fatima Gugova, Joel M. Santiaguel, MD, Maria Tarcela Gler, MD 2020-10-09
Does elective orthopaedic surgery in the pandemic era increase the risk of developing COVID-19? A combined analysis of retrospective and prospective study at a national tertiary hospital in Jakarta, Indonesia Coronavirus disease 19 infection, Viral pneumonia elective orthopedic surgery alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Indonesia Indonesia 2020-07-01 2020-08-31 ChiCTR2000038865 Phase Not Applicable No longer recruiting 1 2 Months Achmad Fauzi Kamal, I Wayan Arya Mahendra Karda 2020-10-12
Study on the risk perception, mental health, and behavioural responses of university students in Hong Kong in COVID-19 pandemic Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs) Chinese University of Hong Kong China 2020-10-19 2022-12-31 ChiCTR2000038864 Phase Not Applicable Not yet recruiting 1 26 Months 600 Queenie Hoi Wing WONG 2020-10-09
MALCOV: Malaria as a risk factor for COVID-19 in western Kenya and Burkina Faso Coronavirus disease 19 infection, Plasmodium infection pyronaridine +artesunate alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Liverpool School of Tropical Medicine, London School of Hygiene and Tropical Medicine Bill & Melinda Gates Foundation, Centers for Disease Control and Prevention, Groupe de Recherche Action en Santé (GRAS), Kenya Medical Research Institute Burkina Faso, Kenya 2021-01-11 MALCOV, PACTR202009642148520 Phase 2 Clinical Not yet recruiting 4 142 Chris Drakeley, Feiko ter Kuile, Hellen Barsosio, Simon Kariuki, Sodiomo Sirima 2020-10-09
The COVID-19 Community Engagement Study Coronavirus disease 19 infection community-owned risk communication intervention alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Makerere University Uganda 2020-10-05 PACTR202010729372570 Phase Not Applicable Not yet recruiting 1 800 Daniel Semakula, Nelson Sewankambo 2020-10-09
Interobserver variability and correlation with clinical outcomes in assessing COVID-19 related chest X-ray findings using the Brixia scoring system Coronavirus disease 19 infection Philippine General Hospital Philippines 2020-06-01 2020-09-28 PHRR200929-002986 Phase Not Applicable Completed 1 3 Months Jorrel Vincent Valdez, MD, FPCR, Michelle Regina Castillo, MD, Rovi Niño D. Samedra, MD, FPCR 2020-10-12
A case report on COVID-19 inflammatory syndrome with clinical features resembling Kawasaki disease Coronavirus disease 19 infection, Kawasaki disease IVIg alone, corticosteroids alone Male Columbia University, New York Presbyterian Hospital Phase Not Applicable Status not specified 0 2 2020-10-08
A phase III clinical study to assess two-dose regimen of JNJ-78436735 compared to placebo in the treatment of patients with SARS-CoV-2 infection Coronavirus disease 19 infection JNJ-78436735 alone Johnson & Johnson Phase 3 Clinical Planned 0 2020-10-08
RELEASE: Safety Infusion of Natural Killer Cells or Memory T-Cells as Adoptive Therapy in COVID-19 Pneumonia or Lymphopenia (WHO) Coronavirus disease 19 infection, Lymphocytopenia, Viral pneumonia allogeneic NK cells alone, allogeneic T memory cells alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto de Investigación Hospital Universitario La Paz Asociación Instituto de Investigación Sanitaria BioCruces, Foundation for Health Research and Biomedical Valencia, Universidad Autonoma de Madrid, Universidad Miguel Hernandez de Elche Spain 2020-09-04 2021-03-31 NCT04578210, RELEASE, RELEASE Phase 1/Phase 2 Clinical Recruiting 1 6 Months 58 Antonio Pérez Martínez, Dr, Bernat Soria, Dr, Carlos Solano, Dr, Cristina Eguizabal, Dra, Víctor Alelú Hernández, Mr 2020-10-09
CARE+: Covid-19-associated research on hand eczema in the health sector – Part 1 Coronavirus disease 19 infection, Eczema health education training alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) iDerm an der Universität Osnabrück Germany 2020-11-08 Bo/34/2020, CARE+, DRKS00022957, DRKS00022958 Phase Not Applicable Not yet recruiting 1 260 Cara Symanzik 2020-10-09
Care +: Covid-19-associated research on hand eczema in the health sector – Part 2 Coronavirus disease 19 infection, Eczema DGUV skin washer alone, lipid-containing skin cleanser alone, standard cleanser alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) iDerm an der Universität Osnabrück Germany 2021-01-04 Bo/35/2020, Care +, DRKS00022957, DRKS00022958 Phase Not Applicable Not yet recruiting 1 35 Cara Symanzik 2020-10-09
A trial to evaluate a new COVID-19 rapid test for diagnosis of COVID-19 Coronavirus disease 19 infection COVID-19 rapid test alone Graphene Leaders Canada Inc Canada Phase Not Applicable Planned 1 2020-10-08
Trial to Study the Adjuvant Benefits of Quercetin Phytosome in Patients With COVID-19 Coronavirus disease 19 infection, Inflammatory disease, Respiratory disease, Respiratory distress syndrome, Respiratory failure Quercetin Phytosome plus remdesivir COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Liaquat University of Medical & Health Sciences Pakistan 2020-10-26 2021-04-25 LUMHS/REC/894, NCT04578158 Phase 2 Clinical Not yet recruiting 1 6 Months 200 Prof. Dr. Ikram Din Ujjan, Prof. Dr. Ikram Din Ujjan, MBBS, PhD, Prof. Dr. Saeed Khan 2020-10-12
A clinical trial of HOUND COVID-19 Breathalyzer, the world's first portable breathalyzer to capture SARS-CoV-2 virus in breath of human test subjects Coronavirus disease 19 infection HOUND COVID-19 BREATHALYZER alone Hound Labs Inc Phase Not Applicable Planned 0 2020-10-12
For covid-19 infection prevention measures in sport Coronavirus disease 19 infection exercise test alone, football helmets alone Healthy volunteers accepted, Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) St Marianna University School of Medicine Japan 2020-09-09 UMIN000042034 Phase Not Applicable Not yet recruiting 1 5 Hiroto Fujiya, Ryota Muroi 2020-10-09
NeuroCovid: A Study of Intensive Care-requiring Covid-19 Patients Cognitive disorder, Coronavirus disease 19 infection, Encephalitis Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Karolinska University Hospital Karolinska Institutet Sweden 2020-08-18 2022-11-30 DNR 2020-02760, NCT04578197, NeuroCovid Phase Not Applicable Recruiting 1 27 Months 100 Lars I Eriksson, Prof, Lars I Eriksson, Professor, Mia Kivipelto, Professor 2020-10-09
CEM: Melatonin in COVID-19 Coronavirus disease 19 infection, Inflammatory disease Variable regimens including acetaminophen , hydroxychloroquine , melatonin (Elite factory) , naproxen Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Tehran University of Medical Sciences Iran 2020-08-05 CEM, IR.TUMS.VCR.REC.1399.068, IRCT20200922048804N1 Phase 2 Clinical No longer recruiting 1 20 Nastaran Keyhanian, Zahra Alizadeh, ِDr. Mohammad Ali Sahraian 2020-10-12
Health Care Worker's Perception of Patient Safety During COVID-19 Pandemic Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidad Miguel Hernandez de Elche Pontificia Universidad Catolica De Chile, Universidad Antonio Nariño, Universidad Catolica Santiago de Guayaquil, Universidad de Santander, University of Sao Paulo Ecuador, Spain, Chile, Colombia 2020-09-01 2020-12-15 2020-09, NCT04576299 Phase Not Applicable No longer recruiting 4 3 Months 800 Jose J Mira, PhD 2020-10-11
NeuroCovid: The Norwegian Study of Nervous System Manifestations and Sequelae After COVID-19 Coronavirus disease 19 infection, Psychiatric disorder anti-viral drugs therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Oslo University Hospital Haukeland University Hospital, Helse Stavanger HF, Møre and Romsdal Hospital Trust, Nordlandssykehuset HF, Ostfold Hospital Trust, Sorlandet Hospital, St Olavs Hospital, Sykehuset Innlandet HF, Sykehuset Telemark, Sykehuset i Vestfold HF, University Hospital of North Norway, University Hospital, Akershus, Vestre Viken HF Norway 2020-09-01 2023-12-31 152727, NCT04576351, NeuroCovid Phase Not Applicable Recruiting 15 40 Months 150 Anette Huuse Farmen, MD PhD, Anne Hege Aamodt, MD PhD, Anne Hege Aamodt, MD, PhD, Barbara Ratajczak-Tretel, MD, Christian Samsonsen, MD PhD, Guttorm Eldøen, MD, Hanne F Harbo, MD,PhD,Prof, Heidi Øyen Flemmen, MD, Hilde K Ofte, MD PhD, Linn H Steffensen, MD PhD, MD,PhD,Prof, Marion Boldingh, MD PhD, Martin Kurz, MD PhD Prof, Martin Weisshaar, MD, Mette Bergum, MD, Mona S E Skjelland, MD PhD Prof, Randi Eikeland, MD, Tormod Fladby, MD PhD Prof, Trine H Popperud, MD PhD, Trine H Popperud, MD, PhD, Øyvind G Torkildsen, MD PhD Prof 2020-10-08
Study to Assess the Safety of Ascending Doses of UNI-911 Inhalation in Healthy Volunteers in Preparation for Evaluation in Adults With COVID-19 Coronavirus disease 19 infection niclosamide (COVID-19), UNION therapeutics/ Institut Pasteur Korea alone S phase kinase associated protein 2 inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) UNION therapeutics Denmark Technical University, The Danish National Advanced Technology Foundation, Trial Nation Denmark Denmark 2020-06-29 2020-12-31 NCT04576312, UNI911-101 Phase 1 Clinical Recruiting 3 6 Months 44 Mads Jellingsø, Torben Balchen, Ulf Sjöbring, MD, Wanja Nyoro 2020-10-09
A clinical study of novel and proprietary Aerosolized Delivery System (ADS) to aerosolize and deliver the KL4 surfactant noninvasively in COVID-19 patients that are at high risk of respiratory failure with an intent to avoid mechanical ventilation Coronavirus disease 19 infection Aerosurf (Aerosolized Delivery System) alone, lucinactant (aerosol), Windtree Therapeutics/ Esteve/ Lee's Pharmaceutical alone BMP10 gene inhibitor, BMP15 gene inhibitor Windtree Therapeutics Inc Phase Not Applicable Planned 0 2020-10-07
A study to fully assess the impact of KL4 surfactant on clinical endpoints such as time on mechanical ventilation, time in the ICU, mortality in COVID-19 patients who are intubated and mechanically ventilated for associated lung injury and ARDS Coronavirus disease 19 infection, Lung injury, Respiratory distress syndrome lucinactant (aerosol), Windtree Therapeutics/ Esteve/ Lee's Pharmaceutical alone BMP10 gene inhibitor, BMP15 gene inhibitor Windtree Therapeutics Inc Phase Not Applicable Status not specified 0 2020-10-09
ADVISe: Longitudinal Imaging of Microglial Activation in Different Clinical Variants of Alzheimer's Disease Alzheimers disease, Amnesia, Aphasia, Atrophy, Coronavirus disease 19 infection, Inflammatory disease 11C-ER-176 alone, Lumbar puncture alone, MK-6240-[18F] alone, MRI alone, PET scan alone, florbetaben (18F) alone Beta amyloid modulator Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Columbia University National Institute on Aging US 2020-11-01 2025-05-31 AAAS7810, ADVISe, NCT04576793, R01AG063888 Phase 2 Clinical Recruiting 1 55 Months 100 Aubrey S Johnson, William C Kreisl, MD, Zeljko Tomljanovic, MD 2020-10-09
The effect of cardiac massage training in patients with cardiac arrest with COVID-19 positioned in the ventral position Cardiac arrest, Coronavirus disease 19 infection, Respiratory disease cardiac massage training alone, chest compression alone, instructional video alone, prone position alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidade Federal de Sao Paulo - UNIFESP Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Brazil 2020-08-13 31510320.4.0000.5505, 4.016.959, RBR-2xxrrq, U111112573179 Phase Not Applicable No longer recruiting 1 1000 Comitê de Ética em Pesquisa, Elaine Peixoto Vieira Cavalcante, Juliana Lima Lopes 2020-10-12
The effect of chloroquine, hydroxychloroquine OR ivermectin in patients with severe manifestations of coronavirus Coronavirus disease 19 infection chloroquine difosfate alone, hydroxychloroquine sulfate alone, ivermectin alone Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Brazil 2020-05-01 30605020.7.0000.5302, 4.013.109, RBR-8h7q82 Phase 2 Clinical No longer recruiting 1 167 Allex Jardim Fonseca, ruy guilherme de souza silveira 2020-10-12
Sequelae of SAR-CoV2 infection on Quality of Life and Lung Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chulalongkorn University, Ratchadapiseksompotch Research Fund Thailand 2020-06-11 2021-06-30 TCTR20201006001 Phase Not Applicable Recruiting 1 12 Months 100 Worawan Sirichana 2020-10-09
High-Resolution Computed Tomographic (HRCT) Findings among Reverse Transcription Polymerase Chain Reaction (RT-PCR) Confirmed Coronavirus Disease 2019 (COVID-19) Adult Patients in Southern Philippines Medical Center Coronavirus disease 19 infection High-Resolution Computed Tomography alone Southern Philippines Medical Center Philippines PHRR201001-003007 Phase Not Applicable Not yet recruiting 1 Roman Aldo D. Reyes 2020-10-09
Trial for collection of blood samples from healed COVID-19 patients - research and development of in-vitro diagnostics Coronavirus disease 19 infection blood sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) R-Biopharm Ag Germany 2020-10-02 20-293, DRKS00022406 Phase Not Applicable Recruiting 1 50 Mr. Dr. med. Jan Heyckendorf, Mr. Markus Böhl 2020-10-09
Practices among anesthesiologists during COVID-19 pandemic; the risk and safety concerns Coronavirus disease 19 infection Southern Philippines Medical Center Philippines 2020-10-01 PHRR200929-002985 Phase Not Applicable Not yet recruiting 1 Alyssa Mae D. Albano 2020-10-07
Psychological Impact of Institutional Quarantine Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) PGIMER AND DR RML HOSPITAL India 2020-10-06 CTRI/2020/10/028194 Phase Not Applicable Not yet recruiting 1 100 Pragya Sharma 2020-10-08
Risk Factors and Computed Tomography Findings in COVID-19 Adult respiratory distress syndrome, Coronavirus disease 19 infection, Viral pneumonia Siemens 256-slice multidetector tomograph (SOMATOM) alone, chest computed tomography (CT) scan alone Instituto Nacional de Cardiologia Ignacio Chavez Mexico 2020-04-01 2020-10-01 20-1177, NCT04577105 Phase Not Applicable Completed 1 6 Months 233 Maria Elena Soto, MsC and PhD, Sergio Andres Criales Vera, MD 2020-10-08
Efficacy and Safety of Drug Combination Therapy of Isotretinoin and Some Antifungal Drugs as A Potential Aerosol Therapy for COVID-19: An Innovative Therapeutic Approach COVID-19 (Isotretinoin) Coronavirus disease 19 infection 13-cis-retinoic acid plus itraconazole Lanosterol-14 demethylase inhibitor Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kafrelsheikh University Egypt 2020-10-20 2020-11-20 ISOTRETINOIN, NCT04577378 Phase 2 Clinical Not yet recruiting 1 1 Month 45 Mahmoud Ramadan mohamed Elkazzaz, mahmoud Elkazzaz, B.Sc of biochemistry 2020-10-09
Factors associated with Job Satisfaction, Burnout, and Turnover Intention among Family and Community Medicine Resident Physicians during the COVID-19 pandemic: A Cross-Sectional Study Acute stress disorder, Coronavirus disease 19 infection, Psychiatric disorder Trinity University Philippines 2020-09-09 2021-03-09 PHRR201006-002996 Phase Not Applicable Recruiting 1 6 Months Aleph S. Doctora, Mel Anthony Acuavera 2020-10-09
A phase II/III, double-blind, placebo-controlled clinical trial to evaluate the safety, tolerability and efficacy of CardiolRx in hospitalized COVID-19 patients with a prior history of, or risk factors for, cardiovascular disease (CVD) Coronavirus disease 19 infection cannabidiol (nanoformulation/subcutaneous, heart failure), Cardiol Therapeutics alone Cardiol Therapeutics Inc US Phase 2/Phase 3 Clinical Not yet recruiting 1 422 Dr. Arvind Bhimaraj, Dr. Barry Trachtenberg, Dr. Carsten Tschöpe, Dr. Dennis McNamara, Dr. Leslie Cooper, Dr. Matthias Friedrich, Dr. Peter Liu, Dr. Wilson Tang 2020-10-07
Intravenous Tocilizumab in the Treatment of Patients with Severe and Critical COVID-19-related Pneumonia Coronavirus disease 19 infection, Viral pneumonia tocilizumab (intravenous), Roche/Chugai alone IL-6 receptor antagonist, IL-6 receptor modulator University of the Philippines Manila Philippine Council for Health Research and Development, Roche (Philippines), Inc Philippines 2020-07-16 2021-07-15 2020-CT0552, CTA-2020-20-08-31, PHRR201005-003010 Phase 2/Phase 3 Clinical Not yet recruiting 1 12 Months 98 Aileen David Wang, MD, Albert B. Albay, Jr., MD, Dr. Eric Jason Amante, Eric Jason Amante, MD, Fresthel Monica M. Climacosa, MD, PhD, John Carlo M. Malabad, John Carlo M. Malabad, MD, PhD, Marissa M. Alejandria, MD 2020-10-08
The Wellbeing of Surgical Residents at a Tertiary Level Government Hospital during the COVID-19 Pandemic Coronavirus disease 19 infection Southern Philippines Medical Center Philippines 2020-11-01 PHRR201001-002993 Phase Not Applicable Not yet recruiting 1 Ma. Theresa Monje, Philippe Michel Manalaysay 2020-10-07
A clinical trial to evaluate the effect of Wearable Technology to prevent COVID-19 complications and death for people recovering at home Coronavirus disease 19 infection Wearable Technology alone Albert Einstein College of Medicine, Montefiore Health System US Phase Not Applicable Status not specified 1 Jonathan D. Leff, M.D 2020-10-07
Risk factors for GI bleeding in COVID-19 patients with anti-coagulant use Coronavirus disease 19 infection, Gastrointestinal bleeding Chinese General Hospital and Medical Center Philippines 2020-09-30 PHRR201001-003002 Phase Not Applicable Not yet recruiting 1 Justin Ryan L. Tan, MD 2020-10-08
Outcomes of medical management of COVID-19 patients with GI bleeding Coronavirus disease 19 infection, Gastrointestinal bleeding medical management alone Chinese General Hospital and Medical Center Philippines 2020-10-01 2021-10-01 PHRR201001-003003 Phase Not Applicable Not yet recruiting 1 12 Months Justin Ryan L. Tan, MD 2020-10-08
Study of the use of ozone therapy adjunct to the treatment of Covid-19 infections Coronavirus disease 19 infection auto-hemotherapy alone, rectal ozone alone, the treatment established by the WHO alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Brazil 2020-07-05 30838820.2.1001.5704, 4.141.069, RBR-5v3k5d, U1111-1257-8184 Phase 3 Clinical Recruiting 1 150 Maria Emilia Gadelha Serra 2020-10-13
The effectiveness of online mindfulness training on mental health and quality of work life of nurses fighting on the frontlines against COVID-19 Acute stress disorder, Coronavirus disease 19 infection Mindfulness-based stress reduction training program alone Healthy volunteers accepted Oroumia University of Medical Sciences Iran 2020-09-22 IR.UMSU.REC.1399.105, IRCT20181203041832N1 Phase Not Applicable Recruiting 1 36 Firouzeh Sepehrianazar, Haedeh Feizipour, Iraj Mohebbi, Naser Gharebaghi 2020-10-08
Lessons-learned - developing a strategy for outpatient care during a pandemic in Baden-Württemberg, Germany. Patient characteristics and clinical course of infections with SARS-CoV-2 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Tubingen Ministerium Für Wissenschaft Forschung Und Kunst Baden-Württemberg Germany 2020-10-26 698/2020BO, DRKS00023069 Phase Not Applicable Not yet recruiting 1 2000 Christian Förster, Stefanie Joos 2020-10-08
CRISIS2: A Phase II Study Assessing the Safety and Antiviral Activity of Brequinar in SARS-CoV-2 Out-patients Coronavirus disease 19 infection brequinar alone, standard of care alone Dehydrogenase inhibitor, Dihydroorotate dehydrogenase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Clear Creek Bio, Inc 2020-10-15 2021-02-28 CCB-CRISIS-02, CRISIS2, NCT04575038 Phase 2 Clinical Not yet recruiting 0 4 Months 100 Barbara L Powers, PhD 2020-10-08
Celecoxib effects on COVID-19 patients Coronavirus disease 19 infection, Viral pneumonia celecoxib alone, routine therapy alone Cyclooxygenase 2 inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Zahedan University of Medical Sciences Iran 2020-09-22 IR.ZAUMS.REC.1399.197, IRCT20200907048644N1 Phase 1 Clinical Recruiting 2 60 Dr. Habib Ghaznavi, Dr. Mohammad Kazem Momeni, Dr. Nour Mohammad Bakhshani, Maliheh Metanat, Roghayeh Sheervalilou 2020-10-08
Efficacy and Safety of Molnupiravir (MK-4482) in Hospitalized Adult Participants With COVID-19 Coronavirus disease 19 infection MK-4482 alone RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Merck Sharp & Dohme Corp 2020-10-19 2021-10-18 2020-003367-26, 4482-001, MK-4482-001, NCT04575584 Phase 2/Phase 3 Clinical Not yet recruiting 0 12 Months 1300 Medical Director 2020-10-08
The possible beneficial role of the regular use of potent mouthwash solutions in the treatment of COVID-19 Coronavirus disease 19 infection chlorhexidine gluconate plus hydrogen peroxide Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hamad Medical Corp Qatar 2020-04-30 2020-11-20 ISRCTN10197987, MRC 05-106 Phase 2 Clinical No longer recruiting 2 6 Months 100 Dr Mukhtar 2020-10-08
New Educational Tool for FM Coronavirus disease 19 infection, Fibromyalgia, Pain PNE-explained alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hospital Vall D'Hebron University of South Australia Spain 2020-09-21 2021-10-10 NCT04571853, NEW EDUCATION TOOL Phase Not Applicable Recruiting 1 12 Months 300 Elena Granell, Lorimer Moseley, PhD, Mayte Serrat, MSc, Sara Marsall, PhD 2020-10-08
DeCODe: Detection of COVID-19 Decompensation Coronavirus disease 19 infection PinpointIQ solution (physIQ, Inc.) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) PhysIQ Inc National Cancer Institute, National Institute of Biomedical Imaging and Bioengineering, University of Illinois US 2020-10-05 2021-01-22 CTP-004, DeCODe, NCT04575532 Phase Not Applicable Recruiting 1 3 Months 400 Karen Larimer, PhD 2020-10-08
Remote Yoga Nidra for Anxiety and Sleep Anxiety disorder, Coronavirus disease 19 infection, Sleep disorder Yoga Nidra alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National College of Natural Medicine US 2020-04-15 2020-09-14 NCT04571593, NUNM Phase Not Applicable Completed 1 5 Months 74 Erica M Sharpe, PhD 2020-10-08
Clinical Study Spartan COVID-19 V2 System Coronavirus disease 19 infection Spartan COVID-19 v2 System alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Spartan Bioscience Inc Beaufort Canada, US 2020-10-31 2020-11-30 NCT04575168, VNV-00615 Phase Not Applicable Not yet recruiting 2 1 Month 100 2020-10-08
Effectiveness of VIRTUAL FIBROWALK STUDY Coronavirus disease 19 infection, Fibromyalgia Treatment as Usual (TAU) alone, VIRTUAL FIBROWALK alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hospital Vall D'Hebron Spain 2020-09-21 2021-11-10 NCT04571528, PR(AG)249/2020 Phase Not Applicable Recruiting 1 13 Months 300 Elena Granell, Mayte Serrat, MSc, Sara Marsal, PhD 2020-10-08
RESPECT: A Research Platform to Screen Healthcare Workers Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The University Health Network Canada 2020-04-16 2021-04-16 20-5289, NCT04574765, OZUHN-001, RESPECT Phase Not Applicable Recruiting 1 12 Months 100000 Amit M Oza, MD, Amit Oza, MD 2020-10-08
A study to assess safety and efficacy of PTX-COVID19-B for coronavirus infection Coronavirus disease 19 infection PTX-COVID19-B alone COVID19 Spike glycoprotein modulator University of Toronto Providence Therapeutics Holdings Inc Phase Not Applicable Planned 0 2020-10-06
Prevalence of COVID-19 Infection in a Cohort of Patients Infected by the HIV and Patients Taking PrEP Coronavirus disease 19 infection, HIV infection ELISA test alone, emtricitabine + tenofovir alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hôpital Européen Marseille France 2020-10-31 2022-04-30 2020-A02018-31, NCT04575545 Phase Not Applicable Not yet recruiting 1 18 Months 600 Myriam BENNANI, Patrick PHILIBERT 2020-10-07
HOPE_BRAZIL: A Trial of Hydroxychloroquine Plus Azithromycin in High-Risk COVID-19 Coronavirus disease 19 infection Reuquinol plus azithromycin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Latin American Cooperative Oncology Group Brazil 2020-06-30 HOPE_BRAZIL, LACOG 0220, NCT04575558 Phase 2 Clinical Terminated 7 2020-10-07
I-RAMIC: IRAK4 Inhibition in Treatment of COVID-19 With ARDS Coronavirus disease 19 infection, Inflammatory disease, Respiratory distress syndrome PF-06650833 alone, standard of care treatment alone, PF-06650833 plus ritonavir Cytochrome P450 3A4 inhibitor, HIV protease inhibitor, HIV-1 protease inhibitor, IRAK-4 protein kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Yale University Pfizer Inc US 2020-10-10 2021-03-31 2000028042, I-RAMIC, NCT04575610 Phase 2 Clinical Not yet recruiting 1 5 Months 68 Hyung Chun, MD, Kelly Borges, MS, BS 2020-10-08
Evaluation of the effect of nano-based inhalation solution to relieve shortness of breath in COVID-19 patients Coronavirus disease 19 infection, Dyspnea, Lung infection, Respiratory disease corticosteroid therapy alone, nebulizer mask alone, Variable regimens including colloidal silver nasal spray , dexamethasone , heparin , interferon beta-1a , interferon beta-1b , prednisolone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ahvaz University of Medical Sciences Iran 2020-08-22 IR.AJUMS.REC.1399.345, IRCT20190226042851N1 Phase 3 Clinical No longer recruiting 1 40 Fatemeh ahmadi, Hakim abiavy, Yousefi farid, mohamad badavi 2020-10-07
A trial to evaluate merimepodib monotherapy for the treatment of COVID-19 patients in the outpatient setting Coronavirus disease 19 infection merimepodib alone Inosine monophosphate dehydrogenase inhibitor Biosig Technologies Inc Phase Not Applicable Planned 0 2020-10-06
Efficacy and Safety of Molnupiravir (MK-4482) in Non-Hospitalized, Adult Participants With COVID-19 Coronavirus disease 19 infection MK-4482 alone RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Merck Sharp & Dohme Corp 2020-10-19 2021-10-14 2020-003368-24, 4482-002, MK-4482-002, NCT04575597 Phase 2/Phase 3 Clinical Not yet recruiting 0 11 Months 1450 Medical Director 2020-10-12
A Study of RLS-0071 in Patients With Acute Lung Injury Due to COVID-19 Pneumonia in Early Respiratory Failure Acute lung injury, Coronavirus disease 19 infection, Hypoxia, Inflammatory disease, Respiratory failure, Viral pneumonia PIC1-01 alone Complement C1s subcomponent inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) ReAlta Life Sciences Inc US 2020-10-31 2021-07-31 NCT04574869, RLS-0071-102 Phase 1 Clinical Not yet recruiting 1 9 Months 42 Efrain Garcia, MD, Kenji Cunnion, MD, MPH, Linda Dell, Naty Diaz, Rocio Navarro 2020-10-12
A new observational study finds patients in the hospital for COVID-19 have high levels of soluble urokinase receptor (suPAR) Coronavirus disease 19 infection University of Michigan Phase Not Applicable Status not specified 0 352 2020-10-07
A global, phase II/III study to assess safety and efficacy of COVID-19 vaccine Coronavirus disease 19 infection SCB-2019 alone COVID19 Spike glycoprotein modulator Clover Biopharmaceuticals Inc Coalition for Epidemic Preparedness Innovations 2020-12-31 Phase 2/Phase 3 Clinical Planned 0 2020-10-07
A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Safety, Tolerability, and Preliminary Efficacy of Intravenous Allogeneic Mesenchymal Stem Cells in Patients with Moderate to Severe Lung Injury due to COVID-19 Coronavirus disease 19 infection Allogeneic Mesenchymal Stem Cells, Stemedica Cell Technologies, Inc alone, standard treatment alone Stemedica Cell Technologies Inc Phase 2 Clinical Not yet recruiting 0 40 2020-10-06
MAVIPAN: My Life and the COVID-19 Pandemic Coronavirus disease 19 infection, Psychiatric disorder Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universite Laval CISSS de Chaudiere-Appalaches, Center for Interdisciplinary Research in Rehabilitation and Social Integration, Cervo Brain Research Centre, Réseau Provincial de Recherche en Adaptation-Réadaptation, Réseau québécois de recherche sur le vieillissement Canada 2020-04-29 2025-04-29 MAVIPAN, NCT04575571, TO BE ASSIGNED Phase Not Applicable Recruiting 1 60 Months 5000 Annie LeBlanc, PhD, Marie Baron, PhD 2020-10-07
Online multicomponent health intervention to support children with special education needs (SEN) and their families during COVID-19 pandemic Attention deficit hyperactivity disorder, Coronavirus disease 19 infection multi-component online health intervention alone Preschool Children (2-5 yrs), Children (6-12 yrs) Hong Kong Jockey Club China 2020-11-02 2021-12-02 ChiCTR2000038827 Phase Not Applicable Not yet recruiting 1 13 Months 1500 Prof. Eric Lee Kam Pui, Yuk Fai Ryan Ho 2020-10-07
HARD-COVID19: Health care workers exposed to COVID-19 Coronavirus disease 19 infection EMDR therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Tours INSERM 2020-10-15 2022-07-15 1-20-046 ID 48680, 2020-A01642-37, DR200160-HARD-COVID-19, HARD-COVID19, NCT04570202 Phase Not Applicable Not yet recruiting 0 21 Months 900 Wiebe de JONG, MSc, Wissam EL-HAGE, MD-PhD 2020-10-08
Covid19Reh: Cardiorespiratory Exercise & Chinese Medicine for Rehabilitation of Discharged Coronavirus Disease (COVID-19) Patients Coronavirus disease 19 infection, Pulmonary fibrosis cardiorespiratory exercise alone, modified Bai He Gu Jin Tang alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hong Kong Baptist University Chinese University of Hong Kong, Hong Kong Polytechnic University, The University of Hong Kong, University of California San Diego, University of South Wales, Yale University Hong Kong 2020-10-01 2023-06-30 Covid19Reh, HKCOVID19REHAB, NCT04572360 Phase Not Applicable Not yet recruiting 1 33 Months 172 Julien Baker, Ph.D, D.Sc, Linda Zhong, Linda Zhong, MD,PhD, Zhaoxiang Bian, Ph.D 2020-10-08
VPPIA: Virtual Parental Presence on Induction Anxiety disorder, Coronavirus disease 19 infection Use of Facetime with child and parents during induction alone Preschool Children (2-5 yrs), Children (6-12 yrs) Cincinnati Children's Hospital Medical Center Hospital for Sick Children US, Canada 2020-10-31 2022-12-31 2020-0371, NCT04574219, VPPIA Phase Not Applicable Not yet recruiting 2 26 Months 184 Clyde Matava, MD, Fahad Alam, MD, Kennth Goldschneider, MD, Kristie Geisler, BS, CCRP, Monica Caldeira-Kulbakas, Sawita Kanavitoon, Vanessa Olbrecht, MD 2020-10-08
KITCHEN: Keeping Infants Term - a Controlled High-risk Patient Enquiry Coronavirus disease 19 infection, Premature labor Multimodal intervention strategy alone Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sera Prognostics Inc 2020-09-30 2025-06-30 1760 KITCHEN, KITCHEN, NCT04301518, SP019 KITCHEN Phase Not Applicable Not yet recruiting 0 57 Months 6500 Ashley Magnavita, MPH, Brian Iriye, MD, Gregory Massey 2020-10-08
Self-Breathe RCT for Chronic Breathlessness Asthma, Bronchiectasis, Cancer, Cardiac failure, Chronic obstructive pulmonary disease, Coronavirus disease 19 infection, Cystic fibrosis, Dyspnea, Interstitial lung disease, Liver failure, Renal failure, Sickle cell anemia SELF-BREATHE alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kings College Hospital NHS Trust King's College London 2020-12-03 2022-06-30 20/LO/1108, IRAS 285303, NCT04574050 Phase Not Applicable Not yet recruiting 0 18 Months 40 2020-10-08
Access to Chiropractic Care During the COVID-19 Healthcare Emergency in Spain Coronavirus disease 19 infection Chiropractic care (more than one visit) alone, Chiropractic care (one visit) alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The University of Birmingham, Universite du Quebec a Trois-Rivieres Spain 2020-05-02 2020-05-27 CHIROCOVID19, NCT04573361 Phase Not Applicable Completed 1 723 Arantxa Ortega de Mues, PhD 2020-10-07
The Delays Among Covid-19 Cases in Samarahan Division, Sarawak Coronavirus disease 19 infection Malaysia 2020-10-01 2020-10-28 56468, NMRR-20-2122-56468 Phase Not Applicable Status not specified 1 Dr. Mohd Fahmi Bin Ismail 2020-10-08
Predicting Favorable Outcomes in Hospitalized Covid-19 Patients Coronavirus disease 19 infection EPIC risk score display alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) NYU Langone Health US 2020-05-15 2021-05-15 NCT04570488, PAU COVID19 RCT Phase Not Applicable Recruiting 1 12 Months 12000 Ashley Bagheri, MS, Jonathan Austrian, MD 2020-10-07
Online Education Intervention to Reduce Ageism Among Undergraduate Students Aging, Coronavirus disease 19 infection Online educational intervention to reduce ageism alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Mississippi 2020-09-28 2020-10-31 21X-046, NCT04570917 Phase Not Applicable Not yet recruiting 0 1 Month 121 Daniel Riche, Nadeeja Wijayatunga 2020-10-07
Mild Hypothermia for COVID-19 ARDS Coronavirus disease 19 infection, Respiratory distress syndrome Arctic Sun 5000 alone, hypothermia alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Northwell Health Inc US 2020-05-18 2020-12-31 NCT04570462, PROTOCOL 5.18.2020 APPROVED Phase Not Applicable Recruiting 1 7 Months 20 Efstathia A Mihelis, MBA, Pey-Jen Yu, Pey-Jen Yu, MD 2020-10-07
MICIn: Investigating the COVID-19 mucosal immunity of children in Indonesia Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Diponegoro University Indonesia 2020-05-01 2021-10-15 ISRCTN32891583, MICIN210920, MICIn Phase Not Applicable Not yet recruiting 1 17 Months 100 Mrs RizkeCiptaningtyas 2020-10-08
Safety and Efficacy of Trans-Sodium Crocetinate (TSC) in SARS-CoV-2 (COVID-19) Infected Subjects Coronavirus disease 19 infection, Hypoxia standard of care alone, trans sodium crocetinate (intravenous), Diffusion Pharmaceuticals alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Diffusion Pharmaceuticals LLC Romania 2020-09-10 2021-12-14 100-303, NCT04573322 Phase 1/Phase 2 Clinical Recruiting 1 15 Months 224 Adrian Streinu Cercel, MD, Anna Grace, MA, BSN, Harry N Cook, RPh/MBA 2020-10-07
Assessment of the effect of nanocurcumin supplement in patients with COVID-19 Coronavirus disease 19 infection, Lower respiratory tract infection, Upper respiratory tract infection nanocurcumin (Exir Nano Sina Company) alone, routine treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Tehran University of Medical Sciences Iran 2020-05-21 2020-12-20 IR.TUMS.VCR.REC.1399.28, IRCT20131125015536N13 Phase Not Applicable Recruiting 2 7 Months 48 Mohammad Javad Hossein Zadeh, Neda Alijani, Saied Reza Jamali Moghadam, Tehran University of Medical Sciences 2020-10-07
SeaCole: Evaluating a new model of rehabilitation for individuals recovering from COVID-19 Coronavirus disease 19 infection Rehabilitation Program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Nuffield Health Bournemouth UK 2020-04-06 2023-12-31 ISRCTN14707226, NHCRP001, SeaCole Phase Not Applicable Not yet recruiting 1 44 Months 500 Dr Benjamin Kelly 2020-10-08
KetoCOVID: Acute Effects of Oral Ketone Ester on Cardiac Function in Patients With COVID-19 Coronavirus disease 19 infection D-beta-hydroxybutyrate-(R)-1,3 butanediol monoester alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Steno Diabetes Center Odense Denmark 2020-10-01 2022-01-01 H-20021500, KetoCOVID, NCT04573764 Phase Not Applicable Not yet recruiting 1 15 Months 12 Jens Christian Laursen, MD, Peter Rossing, MD, Tor Biering-Sørensen, MD 2020-10-13
Treatment With Anti-SARS-CoV-2 Immunoglobulin In Patients With COVID-19 Coronavirus disease 19 infection anti-SARS-CoV-2 equine immunoglobulin (F(ab')2) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Instituto D'Or de Pesquisa 2020-12-01 2021-03-31 NCT04573855, PCL04/2020 Phase 1/Phase 2 Clinical Not yet recruiting 0 4 Months 41 2020-10-07
T Cells Response to SARS COV2 Peptides Coronavirus disease 19 infection ImmunoBiopsy metabolic activity method test (Savicell Diagnostic Ltd) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Savicell Diagnostic Ltd Israel 2020-10-10 2021-10-10 NCT04573348, PBMC _COVID 19 Phase Not Applicable Not yet recruiting 1 12 Months 400 Irena Shahar, BA, Shafrira Shai, PhD, Yochai Adir, Prof 2020-10-07
START: A Registry Study of COVID-19 Serological and Virological Testing to Accelerate Recovery and Transition Coronavirus disease 19 infection blood sampling alone, standard of care PCR test alone, standard of care clinical antibody test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Kentucky US 2020-05-15 2023-12-31 NCT04573634, PHARM-20-COVID19-START, START Phase Not Applicable Recruiting 1 43 Months 960 Derek Forster, MD, Jill Kolesar, PharmD, MS 2020-10-07
Mesenchymal Stem Cells for the Treatment of COVID-19 Coronavirus disease 19 infection mesenchymal stem cells (PrimePro) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) US 2020-04-24 2020-09-01 NCT04573270, PRO00043080 Phase 1 Clinical Completed 1 4 Months 40 Ernst R Von Schwarz, MD, PhD 2020-10-07
AEC COVID-19: National Study 'AEC COVID-19' Coronavirus disease 19 infection Surgical procedure alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospitales Universitarios Virgen del Rocío Spain 2020-03-01 2020-09-30 AEC COVID-19, AEC-COVID, NCT04573868 Phase Not Applicable Recruiting 1 7 Months 1000 Isaias Alarcón, MD PhD, Salvador Morales, Salvador Morales-Conde, Salvador Morales-Conde, MD PhD 2020-10-06
Coping with COVID Pandemic Coronavirus disease 19 infection Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bangladesh Health Professions Institute Bangladesh 2020-10-10 CTRI/2020/10/028196 Phase Not Applicable Not yet recruiting 1 3000 Asma Islam, K M Amran Hossain, Professor Md Obaidul Haque 2020-10-05
An observational, post-registrational study to evaluate the safety and efficacy of Avifavir in the treatment of patients with COVID-19 infection Coronavirus disease 19 infection favipiravir alone RNA polymerase inhibitor ChemRar Pharma Russian Direct Investment Fund Russian Federation Phase 4 Clinical Status not specified 1 940 2020-10-05
Clinical profile of neonates with suspected or proven SARS-CoV-2 infection Coronavirus disease 19 infection, Viral pneumonia Newborn Infants (up to 5 months) Government Medical College and Hospital,Chandigarh India 2020-10-12 CTRI/2020/10/028202 Phase Not Applicable Not yet recruiting 1 30 Deepak Chawla 2020-10-06
The role of Yogic breathing techniques in progression and recovery from COVID-19 Coronavirus disease 19 infection Yoga alone, longer duration breathing technique (LDBT) alone, short duration breathing technique (SDBT) alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ministry of Ayush India 2020-10-08 CTRI/2020/10/028195 Phase Not Applicable Not yet recruiting 1 72 Dr Akshay Anand 2020-10-06
The application of ultrasound-guided superior laryngeal nerve block used for alleviation of agitation after endotracheal intubation Agitation, Coronavirus disease 19 infection, Delirium, Viral pneumonia B-guided superior laryngeal nerve block alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Shengjing Hospital of China Medical University, The First Affiliated Hospital of Wenzhou Medical University China 2020-10-01 2021-06-30 ChiCTR2000038690 Phase 2 Clinical Not yet recruiting 2 9 Months 90 Jiehao Sun 2020-10-06
A survey to assess the effectiveness of Arsenicum Album 30C as a Prophylactic medicine against COVID-19 infection Coronavirus disease 19 infection Arsenicum Album 30C alone Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Homoeopathy India 2020-10-04 CTRI/2020/10/028192 Phase Not Applicable Not yet recruiting 1 15000 Dr Raja manoharan, Dr Selvan 2020-10-06
A study to examine the impact of chronic rhinosinusitis (CRS) on COVID-19 Coronavirus disease 19 infection, Sinusitis American Academy of Allergy Asthma and Immunology China Phase Not Applicable Status not specified 1 1172 2020-10-05
Effect of fluvoxamine on cytokine in COVID-19 patients Coronavirus disease 19 infection fluvoxamine (Abidi and Sobhan Pharmaceutical companies) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shaheed Beheshti Medical University Iran 2020-07-22 IR.SBMU.NRITLD.REC.1399.177, IRCT20131115015405N4 Phase 2/Phase 3 Clinical No longer recruiting 1 40 Mitra Safa 2020-10-06
Effect of Online Psycho-educational Interventions on Psychological Health of Patients with COVID-19 Acute stress disorder, Coronavirus disease 19 infection cognitive–behavioural techniques alone, mindfulness-based stress reduction techniques alone, multimedia psychoeducational content delivery though whatsApp alone, positive psychotherapy exercise alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shiraz University of Medical Sciences Iran 2020-03-10 2020-05-14 IR.SUMS.REC.1399.011, IRCT20201001048893N1 Phase Not Applicable Completed 2 2 Months 50 Abbas Rezaeianzadeh, Maryam Shaygan, Zahra Yazdani 2020-10-06
Diabetes Outcomes in COVID-19 Pandemic Coronavirus disease 19 infection, Insulin dependent diabetes, Non-insulin dependent diabetes Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) SERVICES INSTITUTE OF MEDICAL SCIENCES Pakistan 2020-06-01 2020-07-30 16102019, NCT04573335 Phase Not Applicable Completed 1 1 Month 1282 Saira Burney, MB, FRCP (Edin) 2020-10-06
Natural History of Post-Coronavirus Disease 19 Convalescence at the National Institutes of Health Chronic fatigue syndrome, Coronavirus disease 19 infection deep phenotyping alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Neurological Disorders and Stroke National Institutes of Health Clinical Center US 2020-10-15 2024-12-31 000089-N, 10000089, NCT04573062 Phase Not Applicable Recruiting 1 50 Months 1000 Angelique Gavin, Avindra Nath, M.D. 2020-10-13
Metabolic Cofactor Supplementation and Hydroxychloroquine Combination in Covid-19 Patients Coronavirus disease 19 infection hydroxychloroquine plus serine + L-carnitine tartrate + N-acetylcysteine + nicotinamide riboside Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Scandibio Therapeutics AB Alanya Alaaddin Keykubat University, Alkü Alanya Education and Research Hospital, Bakirkoy Dr. Sadi Konuk Research and Training Hospital, Bağcılar Training & Research Hospital, Canakkale Onsekiz Mart University, Dr.Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi, Istanbul Bakirkoy Maternity and Children Diseases Hospital, Istanbul Medipol University Hospital, Monitor CRO, Ümraniye Training & Research Hospital Turkey 2020-09-21 2021-03-31 COVID-19-MCS, NCT04573153 Phase 2/Phase 3 Clinical Recruiting 1 6 Months 400 Assoc. Prof. Levent DOĞANAY, MD 2020-10-07
Intervention to promote exercise behavior among older adults under the epidemic of COVID-19 Coronavirus disease 19 infection exercise alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kobe University Japan 2020-09-29 UMIN000041990 Phase Not Applicable Recruiting 1 300 Kazuhiro Harada 2020-10-06
A single-site, single-arm, open, Phase I Study to Evaluate the Safety, tolerability and pharmacokinetic of CD24-Fc in healthy adults Coronavirus disease 19 infection CD24-IgFc alone Signal transducer CD24 modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Beijing Ditan Hospital Capital Medical Universty China 2020-11-05 2021-08-05 ChiCTR2000038672 Phase 1 Clinical Not yet recruiting 1 9 Months 12 Longpin Yin, xianfeng Fang 2020-10-08
Effects of pulmonary rehabilitation in patients with COVID-19 Anxiety disorder, Coronavirus disease 19 infection, Depression, Dyspnea patient health information session alone, psychosocial support alone, pulmonary training rehabilitation alone, respiratory physiotherapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Klinik Bad Reichenhall Hochschule fur Gesundheit, Bochum, Ludwig-Maximilians University of Munich Germany 2020-04-28 20-326, DRKS00023180 Phase Not Applicable Recruiting 1 100 Konrad Schultz 2020-10-07
A clinical trial to focus on patients discharged after hospitalization for moderate to severe COVID-19 disease Coronavirus disease 19 infection National Institutes of Health Phase Not Applicable Planned 0 2020-10-05
A clinical trial to investigate whether anticoagulants or antithrombotic therapy can reduce life-threatening cardiovascular or pulmonary complications in newly diagnosed COVID-19 patients who do not require hospital admission Cardiovascular disease, Coronavirus disease 19 infection, Lung disease apixaban alone, aspirin alone Factor Xa antagonist National Institutes of Health Phase Not Applicable Recruiting 0 2020-10-05
A clinical trial to investigate the safety and effectiveness heparin to prevent clotting events and improve outcomes in hospitalized COVID-19 patients Coronavirus disease 19 infection heparin alone National Institutes of Health Phase Not Applicable Recruiting 0 2020-10-08
PROVID-CAPNETZ: Clinical, molecular and functional biomarkers for Prognosis, pathomechanisms and treatment strategies of COVID-19 (PROVID) Coronavirus disease 19 infection, Lung infection, Respiratory distress syndrome, Viral pneumonia biological sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hannover Medical School Charite Universitaetsmedizin Berlin, Deutsche Forschungsgemeinschaft (DFG), German Federal Ministry of Education and Research, University of Leipzig Germany 2020-10-15 DRKS00022871, Nr. 301-2008, PROVID-CAPNETZ Phase Not Applicable Not yet recruiting 15 400 Grit Barten-Neiner 2020-10-07
Efficacy and safety of chlorpromazine in the treatment of COVID-19 patients Coronavirus disease 19 infection atazanavir + ritonavir (Razavi Pharmaceutical Institute) plus chlorpromazine (Tehran Shimi Company) Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mazandaran University of Medical Sciences Iran 2020-10-31 IR.MAZUMS.REC.1399.617, IRCT20200913048708N1 Phase 2 Clinical Not yet recruiting 1 60 Dr Majid saeedi, Ebrahim Salehifar, Roya Ghasemian 2020-10-06
UVA Light Device to Treat COVID-19 Coronavirus disease 19 infection UV light therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cedars-Sinai Medical Center Aytu BioScience Inc US 2020-10-31 2020-12-31 883, NCT04572399 Phase Not Applicable Recruiting 1 2 Months 5 Cedars-Sinai, George Chaux, MD, Melissa Hampton 2020-10-09
Low Dose Lung Radiotherapy to Treat COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia external beam irradiation (0.5 Gy) alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Lancashire Teaching Hospitals NHS Trust National Institute for Health Research (NIHR) UK 2020-10-31 2021-04-30 285167, NCT04572412 Phase 1 Clinical Not yet recruiting 1 6 Months 13 Aashish Vyas, Dennis Hadjiyiannakis, Research Access 2020-10-06
COVIDTrach: A Cohort Study of Mechanically Ventilated COVID-19 Patients Undergoing Tracheostomy Coronavirus disease 19 infection tracheostomy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University College London UK 2020-08-01 2021-08-01 COVIDTrach, NCT04572438, Z6364106/0000/00/00 Phase Not Applicable Recruiting 1 12 Months 2500 Nick JI Hamilton, MBChB PhD, Nick JI Hamilton, MBcHB PhD 2020-10-07
A case study on verapamil as treatment for refractory status epilepticus secondary to PRES syndrome on a SARS-Cov-2 infected patient Brain disease, Coronavirus disease 19 infection, Status epilepticus ceftriaxone alone, dexamethasone alone, enoxaparin sodium alone, hydroxichloroquine alone, lacosamide alone, levetiracetam alone, lopinavir + ritonavir alone, valproate alone, verapamil alone Calcium channel inhibitor, Dihydropyrimidinase related protein 2 modulator, HIV protease inhibitor, Low molecular weight heparin, Sodium channel modulator Hospital Universitario Severo Ochoa Phase Not Applicable Status not specified 0 1 2020-10-07
FloR COVID-19: Pilot, Randomized, Controlled Trial: Fluoxetine to Reduce Hospitalization From COVID-19 Infection Coronavirus disease 19 infection fluoxetine hydrochloride alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Milton S. Hershey Medical Center US 2020-09-30 2021-10-31 00015598, FloR COVID-19, NCT04570449 Phase 0 Clinical Not yet recruiting 1 13 Months 40 Erika Saunders, MD 2020-10-06
PHYTO CoV: Evaluation of phytopharmaceuticals to improve the prognosis of Covid-19 disease in Togo Coronavirus disease 19 infection Biocire alone, Immunitum alone, Immutop alone, Secure alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Togo 2020-10-15 2021-04-30 PACTR202009483194545, PHYTO CoV Phase Not Applicable Not yet recruiting 3 6 Months 250 ADJOH Seraphin, DAGNRA Claver, EKOUEVI Didier Koumavi, Ihou WATEBA Mageste, KOKOU Kouami, SALOU Mounerou 2020-10-07
Dose Ranging Trial to Assess Safety and Immunogenicity of V-590 (COVID-19 Vaccine) in Healthy Adults Coronavirus disease 19 infection V-590 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) International AIDS Vaccine Initiative, Merck Sharp & Dohme Corp Merck & Co Inc 2020-10-22 2021-12-03 NCT04569786, V590-001 Phase 1 Clinical Not yet recruiting 0 13 Months 252 Medical Director 2020-10-09
COntinuation Versus Interruption of Immunomodulating Drugs in case of an Infectious disease in IMID patients (COVID I2 study), with special attention for COVID 19: a pragmatic, explorative randomized controlled trial Coronavirus disease 19 infection, Crohns disease, Inflammatory bowel disease, Psoriasis, Psoriatic arthritis, Rheumatoid arthritis, Spondylarthritis, Ulcerative colitis continued IA alone, standard of care alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sint Maartenskliniek Netherlands 2020-10-01 2022-10-01 NL73479.091.20, NL8922 Phase Not Applicable Planned 1 24 Months 2200 Merel Opdam 2020-10-08
DIEGO: A diet for the treatment of gout Coronavirus disease 19 infection, Gout usual care alone, whole food plant based diet counselling alone Reade Center for Rehabilitation and Rheumatology Netherlands 2020-09-15 2022-03-31 2020.405 - NL74142.029.20, DIEGO, NL8903 Phase Not Applicable Recruiting 1 18 Months 30 Wendy Walrabenstein 2020-10-09
A Study Looking at the Effectiveness, Immune Response and Safety of a COVID-19 Vaccine in Adults in the United Kingdom Coronavirus disease 19 infection Variable regimens including Matrix M , NVX-CoV2373 , seasonal influenza vaccine (quadrivalent, VLP), Novavax COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Novavax Inc UK Government UK 2020-09-28 2022-01-14 2019nCoV-302, 2020-004123-16, NCT04583995 Phase 3 Clinical Recruiting 19 15 Months 9000 Anna Heinen, CRF Team, Dr. Jane Minton, Eilidh Wright, Lakshmi Kumar, Nargis Hemat, Or go to www.bepartof.bradfordresearch.nhs.uk, Pamela Williams, Paul T Heath, MB BS FRACP FRCPCH, Paula Coventry, Prof. Jeremy Turner, Research Team, Roy Soiza, Seth Toback, MD, Sonia Serrano or Karen Bisnauthsing, St. Helier Site Team, Study Team, Trial Study Coordinator, www.bfwh.nhs.uk 2020-10-13
BCG-PRIME: Bacillu Calmette Geurin vaccination to prevent serious respiratory tract infection and covid-19 in vulnerable elderly - and apative randomized controlled trial Coronavirus disease 19 infection, Respiratory tract infection BCG vaccine alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitair Medisch Centrum Utrecht The Netherlands Organisation for Health Research and Development Netherlands 2020-08-27 2020-003470-47, 74730.041.20, BCG-PRIME, CoV-2_DDI Phase 4 Clinical Not yet recruiting 1 5200 2020-10-07
A Pilot study platform to investigate the pharmacodynamics on QT‐prolongation and pharmacokinetics after multiple dose administration of potential combination treatments for COVID-19 in healthy volunteers Coronavirus disease 19 infection lopinavir + ritonavir plus ribavirin HIV protease inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Medical University of Vienna Austria 2020-09-14 2020-002314-40, CoV-2_DDI Phase 2 Clinical Not yet recruiting 1 16 2020-10-05
A randomized, double-blind, placebo-controlled, adaptive-design study to assess the safety and efficacy of daily 200 mg fluvoxamine as add-on therapy to standard of care in moderate severity COVID-19 patients Coronavirus disease 19 infection fluvoxamine alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Sigmadrugs Kft Hungary 2020-09-17 2020-002299-11, SD-COVID19-01 Phase 2 Clinical Not yet recruiting 1 100 2020-10-08
Study on Traditional Chinese Medicine Intervention Program for the Sequela of novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Jiexingjunzi granule alone, Qibei Fuzheng granule alone Beijing University of Chinese Medicine Beijing institute of Traditional Chinese Medicine China 2020-08-01 2021-08-01 ChiCTR2000038740 Phase 0 Clinical Not yet recruiting 1 12 Months 200 Chengxiang Wang, Shan Zhang 2020-10-07
Analysis on the Distribution of TCM Syndromes in convalescent novel coronavirus pneumonia (COVID-19) patients Coronavirus disease 19 infection, Viral pneumonia Beijing University of Chinese Medicine Beijing institute of Traditional Chinese Medicine China 2020-08-01 ChiCTR2000038739, ChiMCTR2000003991 Phase 0 Clinical Not yet recruiting 1 800 Chengxiang Wang, Shan Zhang 2020-10-06
Angiotensin (1-7) for the Treatment of COVID-19 in Hospitalized Patients Coronavirus disease 19 infection angiotensin (1-7) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Stanford University US 2020-11-30 2021-05-31 58189, NCT04570501 Phase 1/Phase 2 Clinical Not yet recruiting 1 6 Months 160 Kevin V Grimes, MD 2020-10-07
An observational, single-center study to determine if early treatment of patients with COVID-19 pneumonia with tocilizumab and/or steroids was associated with better outcome Coronavirus disease 19 infection, Pneumonia methylprednisolone alone, tocilizumab alone, methylprednisolone plus tocilizumab Universita Degli Studi di Genova Phase Not Applicable Status not specified 0 196 2020-10-04
An experimental study to find out the impact of post COVID physiotherapy and rehabilitation in Bangladesh Coronavirus disease 19 infection physiotherapy alone, rehabilitation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Bangladesh 2020-10-07 CTRI/2020/10/028179 Phase Not Applicable Not yet recruiting 1 300 KM Amran Hossain, Mohammad Anwar Hossain 2020-10-05
A cross sectional study to identify the symptoms that are presenting by COVID-19 suffering people in Bangladesh Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bangladesh 2020-10-05 CTRI/2020/09/028165 Phase Not Applicable Not yet recruiting 1 1000 KM Amran Hossain, Mohammad Anwar Hossain 2020-10-07
Pediatric COVID-19 Antibody Study Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) Yokohama City University Japan Agency for Medical Research and Development Japan 2020-10-12 UMIN000041769 Phase Not Applicable Not yet recruiting 1 50 Kenichi Nishimura, Takeharu Yamanaka 2020-10-04
A clinical trial to know the efficacy of Homoeopathic medicine as an adjuvant therapy to Standard treatment in COVID-19 patients Coronavirus disease 19 infection homoeopathic intervention alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Homoeopathy India 2021-10-04 CTRI/2020/09/028164 Phase Not Applicable Not yet recruiting 1 50 Dr Nithiyaselvi, Dr Raja manoharan 2020-10-04
A prospective cohort study of the effects of COVID-19 in pregnancy and the neonatal period Coronavirus disease 19 infection Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Government Medical College, Nagpur Pakistan, Russian Federation, Nigeria, Argentina, UK, Brazil, Macedonia, The Former Yugoslav Republic of, Spain, Mexico, Egypt, Indonesia, Italy, US, India, France, Ghana, Japan 2020-10-01 CTRI/2020/09/028162 Phase Not Applicable Not yet recruiting 17 1500 Dr Manjushri Waikar 2020-10-03
CPT-R-Nepal: Clinical Protocol for Convalescent Plasma and Remdesivir Therapy in Nepal Coronavirus disease 19 infection standard of care alone, convalescent plasma plus remdesivir COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Nepal Health Research Council Ministry of Health and Population, Nepal Nepal 2020-07-30 2020-12-30 CPT-R-Nepal, NCT04570982, NHRC2020-001 Phase Not Applicable Recruiting 6 5 Months 200 Anup Bastola, MD., Dr. Pradip Gyanwali,MD, Janak Koirala, MD, MPH, Krishna Pokhrel, MD., Meghnath Dhimal, PhD, Pradip Gyanwali, MD, Rajan Pandey, MD., Santa K Das, MD., Saroj Bhattarai, MSc., Sher B Kamar, MD., Uday N Singh, MD. 2020-10-03
Oral VIRANORM (Ayurvedic Proprietary Medicine) Compared to Placebo in Subjects with Asymptomatic or Mild COVID-19 Coronavirus disease 19 infection Standard of Care (SOC) alone, VIRANORM alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) India 2020-10-05 CTRI/2020/09/028158 Phase Not Applicable Not yet recruiting 3 250 Dr Padmanaban KG, Dr S Poorna Prasad, Dr Sridhar MK, Dr V Channaraya 2020-10-03
GI-COVID: GM-CSF Inhalation to Prevent ARDS in COVID-19 Pneumonia Coronavirus disease 19 infection, Hypoxia, Respiratory distress syndrome, Viral pneumonia molgramostim alone, rapid nebulizer system alone CSF-1 agonist, GM-CSF receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Giessen Germany 2020-09-24 2022-12-25 2020-001654-21, GI-COVID, KKS-279, NCT04569877 Phase 2 Clinical Recruiting 1 27 Months 238 Nelli Ens-Jäger, Susanne Herold, Prof., Susanne Herold, Prof. Dr. 2020-10-06
Perspective of MBBS Students towards Teaching through Onscreen Classes Coronavirus disease 19 infection Onscreen classes alone Adolescents (13-17 yrs), Young Adults (18-44 yrs) Punjab Institute Of Medical Sciences India 2020-10-10 CTRI/2020/09/028157 Phase Not Applicable Not yet recruiting 1 500 Dr Baljit Jassal, Dr Nipunjot Grewal, Rakesh Kumar 2020-10-01
Multicenter Study of the Integrative and Complementary Practice of the Use of Ozone Gas in Outpatients with COVID-19 Coronavirus disease 19 infection conventional treatment alone, ozone therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Brazil 2020-09-25 30883120.8.1001.0008, 4,100,138, RBR-97nt6j, U1111-1257-7973 Phase 1/Phase 2 Clinical Not yet recruiting 1 142 Arnoldo de Souza 2020-10-03
Comparative Study of Artificial Intelligence and Radiologists in Assessing Severity of COVID19 Patient Images Coronavirus disease 19 infection LungIQ alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) India 2020-10-04 CTRI/2020/09/028156 Phase Not Applicable Not yet recruiting 1 500 Dr Amit Kumar Sahu 2020-10-03
A survey is to study the prophylactic effect of homoeopathic medicine namely Arsenicum album 30 against COVID 19 infection in Madurai Tamilnadu Coronavirus disease 19 infection Arsenicum Album 30C alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Homoeopathy India 2020-10-05 CTRI/2020/09/028153 Phase Not Applicable Not yet recruiting 1 10000 Dr Austin Jose, Dr karthikeyan 2020-10-03
Oral VIRAHALT (Novel Immunomodulatory Herbal combination) Compared to standard of care in Subjects with Moderate to Severe COVID-19 Coronavirus disease 19 infection Standard of Care alone, VIRAHALT (Immunomodulatory Herbal combination) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) India 2020-10-05 CTRI/2020/09/028133 Phase Not Applicable Recruiting 2 60 Dr Padmanaban KG, Dr S Poorna Prasad, Dr V Channaraya 2020-10-03
Research on the maintenance and improvement of physical and mental functions of elderly people under the self-restraint caused by COVID-19 by using a remote system to connect their homes Coronavirus disease 19 infection, Muscle weakness, Psychiatric disorder information and communication technology alone, online gymnastics and exercise instructions alone, online interactive communication alone, salon-gymnastics physical therapy alone, tele-rehabilitation alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) Japan 2020-07-01 UMIN000041458 Phase Not Applicable Not yet recruiting 1 40 Kazunori Kojima 2020-10-05
NHS CHECK: The psychosocial impact of the COVID-19 pandemic on NHS affiliated staff - monitoring the response to the pandemic and the evaluation of local and national staff support programs Coronavirus disease 19 infection, Psychiatric disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) King's College London Medical Research Council, NIHR Maudsley Biomedical Research Centre, Rosetrees Trust, University College London UK 2020-04-01 2022-04-23 IRAS 282686, CPMS 46176, ISRCTN18395399, NHS CHECK Phase Not Applicable Recruiting 18 24 Months 20000 Miss Rupa Bhundia, Prof Simon Wessely 2020-10-06
Auscul-X: Evaluating Auscul-X, a Touch Free Digital Stethoscope Coronavirus disease 19 infection Auscul-X System alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ottawa Heart Institute Research Corp Canada 2020-09-30 2021-01-31 AUSCUL-X, Auscul-X, NCT04570189 Phase Not Applicable Not yet recruiting 1 4 Months 40 Aun Yeong Chong, BSc(Med),MD, Benjamin Chow, MD, Benjamin Chow, MD,FRCPC, Farrah Ahmed, BSc., John Phillips, BSc., Melissa Spero, CRN, CCRP 2020-10-07
Intravenous L-Citrulline to Delay and Potentially Prevent the Need for Invasive Mechanical Ventilation for Acute Hypoxemic Respiratory Failure in Patients With COVID-19 (SARS-CoV-2) Illness Coronavirus disease 19 infection, Hypoxia, Respiratory failure L-citrulline alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Asklepion Pharmaceuticals LLC US 2020-09-28 2021-12-28 CIT-COVID19-002-01, NCT04570384 Phase 2 Clinical Not yet recruiting 1 15 Months 60 Gurdyal Kalsi, MD, MFPM, Michael P Wilson, MD, Nikhil K Meena, MD, Study Site Contact, Vincent Elliott 2020-10-08
Effect of Nasal Steroid in the Treatment of Anosmia Due to COVID-19 Disease Ageusia, Coronavirus disease 19 infection, Dysomia Ophtamesone alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Iraq 2020-08-01 2020-10-15 1148, NCT04569825 Phase 0 Clinical Recruiting 1 2 Months 250 Raid M Al-Ani, FIBMS (ENT) 2020-10-07
Ravulizumab and COVID-19 Coronavirus disease 19 infection, Thrombotic microangiopathy ravulizumab alone, standard care alone Complement C5 factor inhibitor, IgG receptor FcRn large subunit p51 modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Brigham & Women's Hospital US 2020-11-30 2021-11-30 092420, NCT04570397 Phase 3 Clinical Not yet recruiting 1 12 Months 32 Aliza Anwar Memon, M.B.B.S, Andrew M Siedlecki, M.D 2020-10-05
A cross sectional study to assess the impact of COVID-19 on patints with non communicable disease at AYUSH LSD clinics Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Council for Research in Homoeopathy India 2020-10-05 CTRI/2020/09/028132 Phase Not Applicable Not yet recruiting 2 450 Dr Debadatta Nayak, Dr Praveen Oberai, Dr Varanasi Roja 2020-10-01
BigCoviData: Clinical Characteristics and Prognostic Factors of Patients With COVID-19 (Coronavirus Disease 2019) Coronavirus disease 19 infection, Viral pneumonia Big Data system alone Castilla-La Mancha Health Service Spain 2020-01-01 2021-10-30 BIGCOVIDATA, BigCoviData, NCT04569851 Phase Not Applicable Recruiting 2 21 Months 100000 Joan B Soriano, MD, PhD, José Luis Izquierdo, MD, PhD, Julio Ancochea, MD, PhD 2020-10-05
A study of Cordyceps Capsules as an Add-On Therapy in patients with moderate COVID 19 Infection Coronavirus disease 19 infection Cordyceps Capsules alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) India 2020-10-02 CTRI/2020/09/028131, Cordyceps-2001 Phase Not Applicable Not yet recruiting 1 60 Dr Sagar Sinha, Prof Dr Siddharth P Dubhashi 2020-10-05
Homoeopathy in the prevention of COVID-19 Coronavirus disease 19 infection Arsenicum album 30 alone, Influenzinum 30 alone, Oscillococcinum alone Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Mahesh Bhattacharyya Homoeopathic Medical College, Ministry of Ayush India 2020-10-06 CTRI/2020/09/028122 Phase 3 Clinical Not yet recruiting 1 15992 Malay Mundle, Shubhamoy Ghosh 2020-10-05
ANTIOX-COVID: Antioxidants as Adjuvant Therapy to Standard Therapy in Patients With COVID-19 Coronavirus disease 19 infection, Septic shock, Viral pneumonia Variable regimens including N-acetyl cysteine , melatonin , pentoxifylline , vitamin C , vitamin E Phosphoric diester hydrolase inhibitor Instituto Nacional de Cardiologia Ignacio Chavez, Instituto Nacional de Ciencias Medicas y Nutricion Mexico 2020-08-19 2020-11-15 09-CEI-011-20160627, ANTIOX-COVID, NCT04570254 Phase 2 Clinical No longer recruiting 1 2 Months 11 Adrián Palacios Chavarria, MD, José Guillermo Domínguez Cherit, MD, Maria Elena Soto Lopez, PhD 2020-10-07
A study to evaluate the response to and recovery from total knee arthroplasty (TKA) in patients with antibodies to COVID-19 Coronavirus disease 19 infection, Knee injury total knee arthroplasty (TKA) alone Hospital for Special Surgery NY US Phase Not Applicable Status not specified 1 Meghan A. Kirksey, Miguel Otero, Peter K. Sculco 2020-10-01
A clinical study to evaluate the mechanisms of cytokine storm in patients with COVID-19 Coronavirus disease 19 infection anakinra alone Type I IL-1 receptor antagonist Hospital for Special Surgery NY US Phase Not Applicable Status not specified 1 Lionel B. Ivashkiv, Mary K. Crow, Mikhail Olferiev 2020-10-01
STORM-HCW: Screening of Health-care Workers in an University Hospital for SARS-CoV-2 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Milano-Bicocca Italy 2020-06-01 2020-12-01 NCT04567836, STORM-HCW, STORM-HCW Phase Not Applicable Recruiting 1 6 Months 3000 Paolo Bonfanti 2020-10-08
HOW-R-U? CTP: Feasibility and acceptability of a volunteer-peer telephone support programme - A COVID-19 response Coronavirus disease 19 infection, Depression supportive telephone calls alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Northern Hospital, Australia Australia 2020-10-05 ACTRN12620000975998, HOW-R-U? CTP Phase Not Applicable Not yet recruiting 2 100 Dr Marissa Dickins, Prof Judy Lowthian 2020-10-13
National Asthma Treatment Survey in Australian adults Coronavirus disease 19 infection web-based survey alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Oceanic Ancestry National Health and Medical Research Council, Woolcock Institute of Medical Research Australia, New Zealand 2020-11-01 2020-11-15 ACTRN12620000977976p, U1111-1257-3764 Phase Not Applicable Not yet recruiting 2 8000 Dr Sharon Davis, Prof Helen Reddel 2020-10-13
TPEP-Corona-1: A randomized, double-blind, placebo-controlled trial of oral ivermectin for outpatient treatment of those at high risk for hospitalization due to COVID-19 Coronavirus disease 19 infection, Viral pneumonia ivermectin alone Chloride channel modulator Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Neuroscience Trials Australia Leona M and Harry B Helmsley Charitable Trust Australia 2020-10-05 ACTRN12620000982910p, TPEP-Corona-1 Phase 3 Clinical Not yet recruiting 1 400 Dr Mark Stein, Ms Michele Sallaberger 2020-10-13
Micronized and Ultramicronized Palmitoylethanolamide in COVID-19 Patients Coronavirus disease 19 infection, Inflammatory disease, Neuritis, Viral pneumonia Normast MPS (Epitech Group Srl) alone, standard therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Epitech Group Srl Azienda Ospedaliera Sant' Andrea Italy 2020-10-31 2021-11-30 NCT04568876, NORM_MPS-COVID, NORM_MPS_11 Phase 4 Clinical Not yet recruiting 1 13 Months 40 Epitech Group SpA Clinical Research, Prof.ssa Flaminia Coluzzi, MD 2020-10-03
The Phase I Clinical Trial of Booster Vaccination of Adenovirus Type-5 Vectored COVID-19 Vaccine Coronavirus disease 19 infection Ad5-nCoV alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Jiangsu Province Centers for Disease Control and Prevention China 2020-09-26 2021-09-27 JSVCT100, NCT04568811 Phase 1 Clinical No longer recruiting 1 12 Months 89 2020-10-05
Study of AZD-1222 for the Prevention of COVID-19 in Japan Coronavirus disease 19 infection AZD-1222 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) AstraZeneca plc IQVIA RDS Pty Ltd Japan 2020-08-23 2021-09-06 D8111C00002, NCT04568031 Phase 1/Phase 2 Clinical Recruiting 5 12 Months 12 AstraZeneca Clinical Study Information Center 2020-10-12
SAR-COVID: Argentinian Registry of Patients With Rheumatic Diseases and COVID-19 Infection Coronavirus disease 19 infection, Joint disease Immunosuppressive drug treatment alone, immunomodulatory drug treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Argentina 2020-08-18 2021-12-31 01, NCT04568421, SAR-COVID Phase Not Applicable Recruiting 1 16 Months 3000 Carolina Isnardi, MD, Guillermo Pons-Estel, Guillermo Pons-Estel, PhD, Guillermo Posn-Estel, PhD 2020-10-06
Prevention of COVID-19 Infection to Severe Pneumonia or ARDS Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia mosedipimod alone CCL26 gene inhibitor, TLR modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Enzychem Lifesciences Corp US 2020-10-06 2021-11-30 EC-18-204, NCT04569227 Phase 2 Clinical Not yet recruiting 1 13 Months 60 Dr. Cameron Robert Wolfe, Ji Sun Park, Ph.D., John Choi, M.S. 2020-10-01
Minnesota COVID-19 Testing Project Coronavirus disease 19 infection emphasis of government involvement alone, messaging alone, survey incentive alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Harvard University Abdul Latif Jameel Poverty Action Lab US 2020-09-28 2021-06-30 IRB20-1444, NCT04568889 Phase Not Applicable Not yet recruiting 1 9 Months 1000 Marcella Alsan, MD, MPH, PhD, Min Jeong (Joyce) Kim, BS 2020-10-06
RECOVER: Effectiveness of an Exercise Re-training Program on Dyspnea in Patients After Acute Respiratory Distress Syndrome Secondary to Severe COVID-19 Pneumonia in Post-ICU Coronavirus disease 19 infection, Dyspnea, Respiratory distress syndrome, Viral pneumonia specific exercise rehabilitation treatment alone, strengthening exercise alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Groupe Hospitalier Paris Saint-Joseph Assistance Publique Hopitaux de Paris, Central Hospital, Versailles, Centre Hospitalier Victor Dupouy, Saint Anne's Hospital France 2020-08-07 2022-05-07 NCT04569266, RECOVER, RECOVER Phase Not Applicable Recruiting 1 21 Months 200 PHILIPPART François, MD, ROMANET Christophe 2020-10-13
BIO-COCO-NEUROSCIENCES: Evaluation of Biological Response to SARS-COV2 (COVID-19) in Patients With Pre-existing Neurological Disease or Newly Neurological Symptoms Coronavirus disease 19 infection, Neurological disease, Psychiatric disorder PCR alone, chest scanner alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris Institut du Cerveau et de la Moelle epiniere France 2020-10-15 2022-10-15 APHP200845, BIO-COCO-NEUROSCIENCES, NCT04568707 Phase Not Applicable Not yet recruiting 1 24 Months 200 Céline LOUAPRE, MD 2020-10-13
A Clinical Evaluation of COVID-19 Rapid Point of Care Antigen Tests Coronavirus disease 19 infection, Respiratory tract infection SARS-CoV-2 direct antigen rapid test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) E25Bio Inc Sarah Cannon Research Institute US 2020-04-24 2020-09-24 E25001_NEU2012, NCT04568356 Phase Not Applicable Completed 3 5 Months 200 Gina Remington, RN MSN, Klepler N De Almeida, MD, Patrice Feaster, RN 2020-10-06
COICA: COVID-19 Infection in Cancer Pantients Coronavirus disease 19 infection, Urinary tract tumor Italy 2020-01-01 2021-08-31 COICA, COICA_PAG_01, NCT04569292 Phase Not Applicable Recruiting 1 20 Months 150 Data Manager Oncology Unit, Giuseppe Di Lorenzo 2020-10-02
Telerehabilitation of Reduced Physiotherapy Service in Covid-19 Pandemic Process in Lung Surgery Patients Coronavirus disease 19 infection, Lung tumor Telerehabilitation alone, exercise program alone, progressive mobilization program alone, teleconference exercise alone, thoracotomy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Istanbul Medipol University Hospital Turkey 2020-09-25 2021-05-01 NCT04568564, PostopTele Phase Not Applicable Recruiting 1 7 Months 40 Esra pehliva 2020-10-01
COVID-19 Tests With Saliva Specimens Coronavirus disease 19 infection Orasure collection kit alone, SDNA1000 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) US 2020-07-28 2021-06-27 NCT04567953, PLRD202001 Phase Not Applicable No longer recruiting 1 11 Months 2000 Wenli Zhou, PhD 2020-10-13
Combination of Chemopreventive Agents (All- Trans Retinoic Acid and Tamoxifen) as Potential Treatment for the Lung Complication of COVID-19 Coronavirus disease 19 infection, Lung disease, Respiratory failure, Respiratory tract infection standard treatment alone, all trans retinoic acid plus tamoxifen Estrogen receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kafrelsheikh University Egypt 2020-09-30 2020-11-30 COVID-2019, NCT04568096 Phase 2 Clinical Not yet recruiting 2 2 Months 160 Mahmoud Elkazzaz, B.Sc,M.Sc in Biochemistry 2020-10-05
A retrospective study to evaluate the efficacy and safety of anakinra in patients with COVID-19 associated pneumonia and acute severe respiratory failure Coronavirus disease 19 infection, Inflammatory disease, Respiratory distress syndrome, Viral pneumonia anakinra alone, standard-of-care treatment alone Type I IL-1 receptor antagonist Aix-Marseille Université France Phase Not Applicable Status not specified 1 22 2020-09-30
RESCUE: Convalescent Plasma in COVID-19 Elderly Patients Coronavirus disease 19 infection, Respiratory failure convalescent plasma alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) Azienda Socio Sanitaria Territoriale di Mantova Italy 2020-05-15 2020-09-03 ASSTMANTOVA, NCT04569188, RESCUE Phase 2 Clinical Completed 1 3 Months 21 Massimo Franchini 2020-10-05
ImmunoCOVID: Evaluation of Humoral Immunity Following COVID-19 in Pregnancy Coronavirus disease 19 infection, Influenza virus infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Imperial College London UK 2020-09-16 2023-07-03 20SM6089, ImmunoCOVID, NCT04568044 Phase Not Applicable Recruiting 2 33 Months 96 Charlotte-Eve Short, PhD, Head of Research Governance and Integrity, Nishel M Shah, PhD, Research Delivery Operations Manager, Senior Research Facilitator 2020-10-01
A case-control study to compare RLF-100 with standard of care in the treatment of patients with critical COVID-19 and respiratory failure Coronavirus disease 19 infection, Respiratory failure aviptadil (inhaled, sarcoidosis/acute lung injury/acute respiratory distress syndrome associated COVID-19), Relief Therapeutics Holding alone Adrenergic receptor antagonist, VIP receptor agonist NeuroRx Inc Phase Not Applicable Status not specified 0 51 2020-10-05
Safety, Tolerability, and Pharmacokinetics of Anti-Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Chicken Egg Antibody (IgY) (COVID-19) Coronavirus disease 19 infection anti-SARS-CoV-2 IgY alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Stanford University Australia 2020-09-18 2020-12-31 CVR001, NCT04567810 Phase 1 Clinical Recruiting 1 3 Months 48 Daria Mochly-Rosen, PhD, Michaela Lucas, MD, Study Team 2020-10-05
Passive Microwave Radiometry (MWR) and AI for COVID-19 Complications Early Diagnostics of Lungs Coronavirus disease 19 infection, Viral pneumonia MWR2020 alone, passive microwave radiometry alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) International Medical University, University of Edinburgh Kyrgyzstan 2020-07-01 2020-08-01 01-2/141 27, NCT04568525 Phase Not Applicable Completed 1 1 Month 195 Batyr Osmonov 2020-10-01
The Noninvasive Ventilation to COVID-19 Patients Coronavirus disease 19 infection, Respiratory failure noninvasive ventilation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The First Affiliated Hospital of Guangzhou Medical College China 2020-02-01 2020-07-01 FAHGUANGZHOUYLS03, NCT04568655 Phase Not Applicable Completed 1 5 Months 23 Zhang Jianheng 2020-10-02
Waxing and Waning of Serum SARS CoV-2-IgG Level in COVID-19 Exposed Population Coronavirus disease 19 infection Pakistan 2020-07-01 2020-11-30 LGH007, NCT04568850 Phase Not Applicable No longer recruiting 1 5 Months 50 Amina Asif, MPhilMicro 2020-10-06
Prevalence and Risk Factors for Venous Thromboembolic Events in Critically Ill Patients With COVID-19 Coronavirus disease 19 infection, Deep vein thrombosis, Respiratory failure color doppler alone, ultrasonography alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Switzerland 2020-03-03 2020-05-28 2020-01266, NCT04567927 Phase Not Applicable Completed 1 2 Months 80 Chiesa Alessandro Felice 2020-10-01
A Survey Study to Assess the Impact of the COVID-19 Pandemic on Participants With Pre-Existing Mental Health Diagnosis Coronavirus disease 19 infection, Psychiatric disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Siyan Clinical Corp US 2020-09-18 2021-12-31 NCT04568135, SCR-SUR-001 Phase Not Applicable Not yet recruiting 2 15 Months 1000 Tiffany Morgan 2020-10-01
Effect of Inhaled Nitric Oxide for the treatment of COVID-19 Coronavirus disease 19 infection nitric oxide alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Council for Scientific and Technological Development Brazil 2020-10-10 34578820.6.1001.5336, 4,282,107, RBR-8nfx26, U1111-1254-0466 Phase 2 Clinical Not yet recruiting 1 110 Marcus Herbert Jones, Marcus Jones 2020-10-05
Presenting Nutrition Characteristics, Comorbidities and Outcomes of COVID-19 in African Humanitarian Settings Coronavirus disease 19 infection Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Johns Hopkins Bloomberg School of Public Health Centers for Disease Control and Prevention Congo, The Democratic Republic of the, Sudan 2020-10-31 2021-03-31 13736, NCT04568499 Phase Not Applicable Not yet recruiting 2 5 Months 1000 Shannon Doocy, PhD 2020-10-01
Prospective Determination of COVID-19 Infection Rate in a Chemotherapy Unit in Mexico Coronavirus disease 19 infection polymerase chain reaction alone Instituto Nacional de Ciencias Medicas y Nutricion National Institute Of Genomic Medicine Mexico Mexico 2020-06-11 2020-10-30 HEM-3412-20-20-1, NCT04567979 Phase Not Applicable No longer recruiting 1 4 Months 149 David Huitzil m, Fidel D Huitzil Meléndez, MD 2020-10-01
COVID-19 Biorepository Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Kansas Medical Center US 2020-04-15 2021-12-31 NCT04568148, STUDY#00145602 Phase Not Applicable Recruiting 1 20 Months 50 Christine M Cook, MD, Leslie A Spikes, MD, Luigi R Boccardi, BS 2020-10-02
Surfactant-BL in Adult Acute Respiratory Distress Syndrome Due to COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure High-flow oxygen therapy alone, Standard treatment alone, non-invasive ventilation alone, surfactant-BL, Biosurf LLC alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Russian Federation 2020-07-03 2021-12-31 NCT04568018, SUR/ARDS-2020 Phase Not Applicable Recruiting 1 17 Months 120 Anastasia Evdokimova, Sergey Avdeev, D.M.S. 2020-10-06
Safety, Tolerability and Immunogenicity of the Candidate Vaccine MVA-SARS-2-S Against COVID-19 Coronavirus disease 19 infection MVA-SARS-2-S alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Universitätsklinikum Hamburg-Eppendorf Deutsches Zentrum für Infektionsforschung, Ludwig-Maximilians University of Munich, Philipps University Marburg Medical Center Germany 2020-10-31 2021-05-31 NCT04569383, UKE-DZIF-SARS-COV-2 Phase 1 Clinical Not yet recruiting 1 7 Months 30 Marylyn M Addo, MD 2020-10-06
Evaluation of Lymphedema Patients Status During COVID-19 Pandemic Anxiety disorder, Coronavirus disease 19 infection, Depression, Lymphedema, Phobia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fatih Sultan Mehmet Training and Research Hospital Turkey 2020-06-01 2020-08-01 FEYZAAKANBEGOGLU, NCT04568005 Phase Not Applicable Completed 1 2 Months 60 Feyza Akan Begoğlu, MD 2020-10-08
CAASP: COVID-19-associated Anxiety of Pregnant Women for Anomalies, Stillbirth and Preterm Labor Anxiety disorder, Coronavirus disease 19 infection Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Martin-Luther-Universitaet Germany 2020-10-01 2021-07-31 CAASP, NCT04568551, UKGEB001 Phase Not Applicable Recruiting 1 10 Months 300 Marcus Riemer, Marcus Riemer, MD 2020-10-05
Rapid Turnaround, Home-based Saliva Testing for COVID-19 Coronavirus disease 19 infection HandyFuge-LAMP alone, Saliva test alone, loop-mediated isothermal amplification (LAMP) assay alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Stanford University US 2020-10-31 2021-04-30 58629, NCT04568122 Phase Not Applicable Not yet recruiting 1 6 Months 3015 Euan A Ashley, MRCP, DPhil, Manisha Desai, PhD, Manu Prakash, PhD 2020-10-13
COVID-19 and Venous Thromboembolism Risk Coronavirus disease 19 infection, Thromboembolism Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of California San Francisco Kaiser Permanente, Patient Centered Outcome Research Institute US 2020-01-01 2022-06-21 NCT04569344, NOACS-1510-32651_ENHANCEMENT Phase Not Applicable Recruiting 2 29 Months 40000 Alan S. Go, MD, Kristi Reynolds, PhD, MPH, Margaret C Fang, MD 2020-10-06
A phase II clinical trial of tolimidone in the treatment of patients who were recently diagnosed with COVID-19, have early symptoms, but were not hospitalized Coronavirus disease 19 infection tolimidone alone Insulin sensitizer, Lyn tyrosine kinase stimulator Melior Pharmaceuticals Inc University of Pittsburgh Medical Center Phase 2 Clinical Planned 0 428 2020-09-30
Effect of poor sleep hygiene and screen time usage on sleep Acute stress disorder, Coronavirus disease 19 infection Young Adults (18-44 yrs) Sri Ramachandra Institute of Higher Education and Research India 2020-10-01 CTRI/2020/09/028083 Phase Not Applicable Not yet recruiting 1 330 Dr Priscilla Johnson, V Sudha Kumari 2020-10-01
ARIAA-2: Adaptability and Resilience in Aging Adults-2 Coronavirus disease 19 infection, Lower back pain Resilience Intervention alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Florida National Institute on Aging US 2020-01-21 2021-05-01 4R00AG052642-03, 5K99AG052642-02, ARIAA-2, IRB201802729, NCT04068922 Phase Not Applicable Recruiting 1 15 Months 60 Emily Bartley, PhD, Emily J Bartley, Ph.D 2020-10-06
REPERCOV: Identifying Functional and Psycho-social Complaints After Hospitalization for SARS-CoV-2 Infection (COVID 19) Coronavirus disease 19 infection, Psychiatric disorder questionnaire alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier le Mans France 2020-06-11 2022-06-11 CHM-2020/S10/04, NCT04561154, REPERCOV Phase Not Applicable Recruiting 1 24 Months 134 Christelle JADEAU, Hikombo HITOTO 2020-10-06
A phase I, multicenter, randomized, controlled trial to evaluate the safety and efficacy of inhaled Ampion in combination with standard of care for the treatment of COVID-19 infected patients hospitalized for respiratory distress Coronavirus disease 19 infection, Respiratory distress syndrome Ampion (intranasal, inflammation), Ampio/DMI Biosciences alone, standard of care alone Stem cell antigen-1 inhibitor Ampio Pharmaceuticals Inc Phase 1 Clinical Not yet recruiting 0 40 2020-09-30
Variation in biochemical parameters in COVID-19 infection Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Sri Ramachandra Institute of Higher Education and Research India 2020-10-01 CTRI/2020/09/028069 Phase Not Applicable Not yet recruiting 1 150 Dr K Sowmya 2020-10-01
The Causal Effects of Old Age Pensions Coronavirus disease 19 infection Assistance with old age pension application alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Bureau of Economic Research Inc India 2019-02-04 2027-12-31 223749, NCT04029194 Phase Not Applicable No longer recruiting 1 106 Months 1459 Esther Duflo 2020-09-30
Self-help Guided by Lay Providers for Anxiety in Older Adults Coronavirus disease 19 infection, Generalized anxiety disorder Self-help guided by a lay provider alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universite Laval Canadian Institutes of Health Research, Convenance institutionnelle CIUSSS de la Capitale-Nationale, Universite de Sherbrooke Canada 2019-03-11 2023-03-31 NCT03768544, SIRUL 118715 Phase Not Applicable Recruiting 3 48 Months 130 Catherine Filion, M.A., Félix-Antoine Desruisseaux, B.A., Patrick Gosselin, Ph.D., Philippe Landreville, Ph.D., René-Marc Lavigne, Ph.D., Sébastien Grenier, Ph.D. 2020-10-05
Vaginal Cleansing Before Cesarean Delivery to Reduce Infection Coronavirus disease 19 infection, Vaginal infection Abdominal Cleansing alone, Vaginal Cleansing alone, betadine alone, chlorhexidine alone, povidone-iodine alone Healthy volunteers accepted, Female Washington University in St Louis US 2015-08-31 2021-03-31 201505127, NCT02495753 Phase 2 Clinical Recruiting 1 67 Months 608 Alison G Cahill, MD, Antonina I Frolova, MD, Lorene A Temming, MD 2020-10-01
An observational, retrospective study to evaluate the outcomes of tocilizumab in patients with severe coronavirus disease 2019 Coronavirus disease 19 infection antiviral agents alone, tocilizumab alone Hamad Medical Corp Phase Not Applicable Status not specified 0 25 2020-10-08
Effectiveness of an equipment to reduce the dispersion of particles in emergency dental care during the Covid-19 pandemic Coronavirus disease 19 infection, Tooth disease protective equipment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Pontifícia Universidade Católica - PUCPR Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul Brazil 2020-09-01 30717820.1.0000.5336, 4.021.042, RBR-9rnkbs, U1111-1258-5375 Phase Not Applicable Recruiting 1 Maximiliano Schunke Gomes 2020-09-30
Supporting the Health and Well-being of Children With Intellectual and Developmental Disability During COVID-19 Pandemic Coronavirus disease 19 infection, Intellectual impairment Best Message + Augmented Message or Implementation Strategy alone, Best Message Alone alone, Focused/Targeted Message alone, General Communication Message alone Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Washington University School of Medicine, US Hugo W. Moser Research Institute at Kennedy Krieger, Inc, National Institutes of Health, University of Missouri US 2020-11-01 2022-09-21 202009060, NCT04565509 Phase Not Applicable Not yet recruiting 2 22 Months 2500 Bradley Schlaggar, MD, PhD, George S Grotto, PhD, Jason G. Newland, MD 2020-10-01
Testing Multiple Behavioral Science Strategies to Increase Flu-Shot Rates Coronavirus disease 19 infection, Influenza virus infection Flu shot text messages alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Pennsylvania State University Geisinger Clinic 2020-09-30 2021-03-31 843523, NCT04565353 Phase Not Applicable Not yet recruiting 0 6 Months 125600 Dena Gromet, PhD, Joseph Kay, PhD 2020-10-01
DPPFit: Developing and Testing a Technology-Based Translation of the DPP to Address Prediabetes in a Primary Care Setting Coronavirus disease 19 infection, Non-insulin dependent diabetes Diabetes Prevention Program alone, Fitbit alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Augusta University US 2020-01-01 2021-02-15 DPPFit, IRB#1193356, NCT04564586 Phase Not Applicable No longer recruiting 1 13 Months 32 Jessica L Stewart, MPH 2020-10-01
Pilot Study to Evaluate Effect of CHX0.12/CPC 0.05 of SARS-CoV-2 Viral Load in COVID-19 Patients Coronavirus disease 19 infection CHX0.12+CPC0.05 oral rinsing alone, Chlorhexidine + Cetyl Pyridinium Chloride alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dentaid, S.L. Colombia 2020-06-18 2020-12-31 COVID-POC1, NCT04563689 Phase Not Applicable Recruiting 1 6 Months 24 Adolfo Contreras, prof, Beatriz Parra, PhD, Juan Gispert, MD, Ruben Leon, PhD, Vanessa Blanc, PhD 2020-10-05
ACPREGCOV: Active Pregnancy Against COVID-19 Coronavirus disease 19 infection, Pregnancy disorder Exercise program alone Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Universidad Politecnica de Madrid Hospital Puerta de Hierro Majadahonda, Hospital Universitario Severo Ochoa, Hospital Vall D'Hebron, University Hospital of Torrejon Spain 2020-08-01 2023-12-31 ACPREGCOV, NCT04563065, UPM-2020-32/33 Phase Not Applicable Recruiting 2 41 Months 280 Aranzazu Martin, Dr, Cristina Silva-Jose, Msc, Cristina Silva-José, MsC, Ignacio Refoyo, Dr, Irene Buhigas, Dr, Irune Alzola, Dr, Javier Coterón, Dr, Javier Gil, Dr, Maia Brik, Dr, Mar Gil, Dr, Miguel Sanchez-Polan, Msc, Rubén Barakat, Rubén Barakat Carballo, Rubén Barakat, Dr, Tirso Perez, Dr, Vanessa Carrero, Dr, Ángeles Blanco, Dr 2020-10-01
XatJove Anoia, as a Tool to Bring Health Services Closer to Teenagers Coronavirus disease 19 infection XatJove Anoia Aplication alone Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs) Jordi Gol i Gurina Foundation Catalan Health Service Spain 2020-10-01 2021-10-11 20/137-P, NCT04562350 Phase Not Applicable Recruiting 1 12 Months 500 Glòria Saüch Valmaña, Josep Vidal-Alaball, PhD, Nuria Carré Llopis, RN, Núria Carré Llopis, RN 2020-10-01
Evaluation of the effect of education in the prevention of covid-19 Coronavirus disease 19 infection protection motivation theory-based educational program alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hamadan University of Medical Sciences Iran 2020-09-22 IR.UMSHA.REC.1399.476, IRCT20200902048598N1 Phase Not Applicable Recruiting 1 200 Dr. Saeed Bashirian, Majid Barati, Roholah Afshar 2020-10-01
Social factors related to COVID 19 Coronavirus disease 19 infection interview alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Tata Memorial Hospital India 2020-10-07 CTRI/2020/09/028090 Phase Not Applicable Not yet recruiting 1 800 Sandeep Tandon 2020-10-01
Role of self sampling in COVID 19 patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute Of Medical Sciences, Rishikesh India 2020-10-05 CTRI/2020/09/028089 Phase Not Applicable Not yet recruiting 1 1350 Dr Amit Kumar 2020-10-01
Effects of Traditional Nasal Saline (Simply Saline) and a Novel Nasal Salt on Aerosol Cleansing Coronavirus disease 19 infection nasal mist calcium salts alone Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Bangalore Baptist Hospital India 2020-10-05 CTRI/2020/09/028084 Phase Not Applicable Not yet recruiting 1 80 Dr Carolin Elizabeth George 2020-09-30
Intubation and ventilatory support in COVID patients: observational study from a tertiary care ICU Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences Jai Prakash Narayan Apex Trauma Centre India 2020-10-02 CTRI/2020/09/028050 Phase Not Applicable Not yet recruiting 1 40 Dr Nishant Patel 2020-09-30
COVID-19: Telemedicine Readiness Coronavirus disease 19 infection telemedicine readiness alone Malaysia 2020-10-15 2021-10-15 56434, NMRR-20-2029-56434 Phase Not Applicable Status not specified 1 12 Months NURIZATI BINTI MAT GHANI 2020-09-30
COVID-19 Spatio-Temporal Modeling Coronavirus disease 19 infection Spatio-Temporal Modeling alone Universiti Putra Malaysia Malaysia 2020-12-01 2022-06-01 56256, NMRR-20-2031-56256 Phase Not Applicable Status not specified 1 18 Months Dr Nur Haizum binti Abd Rahman 2020-09-30
A study to assess aviptadil (inhaled, sarcoidosis/acute lung injury/acute respiratory distress syndrome associated COVID-19), Relief Therapeutics Holding for the treatment of covid-19 and respiratory failure Coronavirus disease 19 infection, Respiratory failure aviptadil (inhaled, sarcoidosis/acute lung injury/acute respiratory distress syndrome associated COVID-19), Relief Therapeutics Holding alone Adrenergic receptor antagonist, VIP receptor agonist NeuroRx Inc, Relief Therapeutics Holding AG Phase Not Applicable Status not specified 0 51 2020-09-29
CAM-Covid-19: Open-Label, Randomized trial of Colchicine, Aspirin and Montelukast in Covid-19 Coronavirus disease 19 infection, Inflammatory disease Standard of Care alone, Variable regimens including Aspirin , colchicine , montelukast sodium Leukotriene D4 antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Indira Gandhi Medical College India 2020-10-31 CAM-Covid-19, CTRI/2020/09/028088 Phase 2 Clinical Not yet recruiting 1 34 Vivek Chauhan 2020-10-05
Phase IIb Clinical Trial of A COVID-19 Vaccine Named Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector) Coronavirus disease 19 infection Ad5-nCoV alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) CanSino Biologics Inc Beijing Institute of Biotechnology, China, Jiangsu Province Centers for Disease Control and Prevention China 2020-09-24 2022-10-20 JSVCT093, NCT04566770 Phase 2b Clinical Recruiting 1 24 Months 481 Fengcai Zhu, MSD, Wenjuan Wang, MSD 2020-10-01
SCREEN: Serology to Covid for Recording Exposures and Evaluating Needs Coronavirus disease 19 infection ELISA alone, biological sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cincinnati Children's Hospital Medical Center US 2020-08-18 2023-12-31 NCT04566965, SCREEN, SCREEN Phase Not Applicable Recruiting 1 40 Months 230 Mary Allen Staat, MD, MPH, Maureen Carolin, Russell Ware, MD, PhD, Sue Poynter Wong, MD, MEd, Teresa Latham 2020-09-30
Co-CLARITY: Convalescent Plasma as Adjunctive Therapy for Hospitalized Patients With COVID-19 Coronavirus disease 19 infection anti-SARS-CoV-2 convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of the Philippines Philippine Council for Health Research and Development Philippines 2020-09-21 2021-06-30 2020-CT0554, Co-CLARITY, NCT04567173, PHRR200824-002868, UPMREB 2020-300-01 Phase 3 Clinical Recruiting 2 9 Months 136 Agnes Evasan, MD, Alric V Mondragon, MD, Anna Flor Malundo, MD, Anne Kristine H Quero, MD, Carlo Francisco N Cortez, MD, Cecile D Dungog, MD, Deonne Thaddeus Gauiran, Deonne Thaddeus Gauiran, Principal Investigator, Deonne Thaddeus V Gauiran, MD, Francisco M Heralde III, PhD, Fresthel Monica M Climacosa, MD PhD, German J Castillo Jr, MD, Ivy Mae S Escasa, MD, Januario Veloso, MD, Jodor Lim, MD, Jose M Carnate Jr, MD, Josephine Anne Lucero, MD, Lynn B Bonifacio, MD, Ma Angelina L Mirasol, MD, Maria Clariza M Santos, MD, Marissa Alejandria, MD MSc, Mark Angelo Ang, MD, Pedrito Y Tagayuna, MD, Rachelle Alfonso, MD, Ruby Anne N King, MD PhD, Sandy Chiong Maganito, MD, Teresita E Dumagay, MD 2020-09-30
ChulaCov19 mRNA Vaccine in Healthy Adults Coronavirus disease 19 infection ChulaCov19 messenger ribonucleic acid alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Chulalongkorn University Faculty of Tropical Medicine, Mahidol University, National Vaccine Institute, Thailand, The National Research Council Of Thailand Thailand 2021-01-31 2021-06-30 CHULAVAC 001, NCT04566276 Phase 1/Phase 2 Clinical Not yet recruiting 2 5 Months 96 Kiat Ruxrungtham, MD, Nitiya Chomchey, PhD, Sivaporn Gatechompol, MD 2020-10-07
Predictive Factors for COVID-19 in Rheumatology Autoimmune disease, Coronavirus disease 19 infection, Musculoskeletal disease disease modifying antirheumatic drug therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundacion Santa Fe De Bogota Colombia 2020-10-31 2021-10-31 FPCOLCOVIDREUMA2020, NCT04567576 Phase Not Applicable Not yet recruiting 1 12 Months 150 Kevin Maldonado Canonn 2020-09-30
PREVAILctDNA: Preventing Viral Pandemic Associated Risk of Cancer Death Using Less Invasive Diagnostic Tests- Liquid Biopsies Biliary cancer, Colorectal tumor, Coronavirus disease 19 infection, Gastrointestinal stromal tumor, Lung tumor, Metastasis, Metastatic bladder cancer, Metastatic pancreas cancer Blood sampling alone, Liquid biopsy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The Royal Marsden NHS Trust UK 2020-06-18 2022-12-31 CCR 5292, NCT04566614, PREVAILctDNA Phase Not Applicable Recruiting 2 30 Months 112 Justin Mencel, MBBS, Naureen Starling, Naureen Starling, MBBS MRCP MD, Scot Davies, CIBiol 2020-09-30
A study to evaluate lipemic serum in patients with CoVID‐19 undergoing lopinavir/ritonavir treatment Coronavirus disease 19 infection, Hypertriglyceridemia lopinavir + ritonavir alone HIV protease inhibitor Male Ministry of Health, Brunei Darussalam Phase Not Applicable Status not specified 0 2 2020-09-29
A trial to evaluate IVIEW-1503 for the treatment of patients with COVID-19 Coronavirus disease 19 infection IVIEW-1503 alone iVIEW Therapeutics Inc University of British Columbia Canada Phase Not Applicable Not yet recruiting 1 2020-09-29
Phase IV study to evaluate the safety and efficacy of Artemisinin- a herbal supplement on COVID-19 subjects Coronavirus disease 19 infection Artemisinin alone, Standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Windlas Biotech Pvt Ltd India 2020-09-30 ARTI/WBPL/P4/2020/01, CTRI/2020/09/028044 Phase 4 Clinical Not yet recruiting 3 120 Dr Antaryami Maharana, Mukesh Kumar 2020-09-30
Clinical study to assess role of Vasa Ghana, Guduchi Ghana and Vasa-Guduchi Ghana in therapeutic management of symptoms in Covid19 Coronavirus disease 19 infection Adhatoda vasica alone,  Tinospora cordifolia alone, Adhatoda vasica plus  Tinospora cordifolia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ministry of Ayush India CTRI/2020/09/028043 Phase 4 Clinical Not yet recruiting 1 50 DR BHAVANA PRASHER, Dr Meera K Bhojani, Prof Tanuja Manoj Nesari 2020-10-01
Seroprevalence of COVID 19 in children Coronavirus disease 19 infection Healthy volunteers accepted, Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Kanchi Kamakoti CHILDS Trust Hospital India 2020-10-05 CTRI/2020/09/028040 Phase Not Applicable Not yet recruiting 1 400 Dr Aishwarya Venkataraman 2020-09-30
Evaluation of severity of chest CT findings in covid 19 patients with pre-existing illness Coronavirus disease 19 infection chest CT findings alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) KIMS Hospital India 2020-10-20 CTRI/2020/09/028087 Phase Not Applicable Not yet recruiting 1 500 Swati Das 2020-09-30
Effect of 12-weeks of Online Sudarshan Kriya Yoga practice on Burnout and Health Parameters among COVID-19 Frontline Warriors Coronavirus disease 19 infection Online Sudarshan Kriya Yoga practice alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute Of Medical Sciences, Rishikesh India 2020-10-08 CTRI/2020/09/028086 Phase Not Applicable Not yet recruiting 1 43 Dr Monika Pathania 2020-09-30
Assessment of Knowledge, Attitude and Practice Towards COVID-19 Pandemic among Hospital Jengka Employees Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Jengka Hospital Malaysia 2020-09-29 2021-02-15 NMRR-20-2044-55325 Phase Not Applicable Not yet recruiting 1 4 Months Mrs. ZURIA IKAZIRA BINTI ZAKARIA 2020-09-30
Mitigation of COVID-19 Clusters in Malaysia Coronavirus disease 19 infection Seberang Jaya Hospital Malaysia 2020-09-24 2020-09-25 NMRR-20-2033-56605 Phase Not Applicable Status not specified 1 DR. MONICA A/P DANIAL 2020-09-30
Evaluation of Atypical imaging features on HRCT CHEST Coronavirus disease 19 infection HRCT alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kalinga Institute of Medical Sciences India 2020-10-20 CTRI/2020/09/028049 Phase Not Applicable Not yet recruiting 1 300 Dr Col Kamal Kumar Sen, Rohit Arora 2020-09-30
Homoeopathy management for covid 19 patients Coronavirus disease 19 infection homoeopathic medicine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Council for Research in Homeopathy Ministry of Ayush India 2020-10-05 CTRI/2020/09/028046 Phase Not Applicable Not yet recruiting 1 100 Dr Sushma Bhtanagar 2020-09-30
Online learning programme for providing cardiopulmonary resuscitation among nurses Cardiac arrest, Coronavirus disease 19 infection Enhancement Training Module on CPR guidelines related to COVID 19 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) All India Institute of Medical Sciences India 2020-09-28 CTRI/2020/09/028045 Phase Not Applicable Not yet recruiting 1 100 POONAM JOSHI 2020-09-30
Double-blind, placebo-controlled, randomized study of the tolerability, safety and immunogenicity of the inactivated whole-virion concentrated purified sorbed vaccine, produced by the Chumakov FSCIRIP Russian Academy of Sciences on volunteers aged 18 to 60 years Coronavirus disease 19 infection inactivated whole-virion concentrated purified coronavirus vaccine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) M P Chumakov Institute of Poliomyelitis and Virus Encephalitides Russian Federation 2020-09-21 2020-12-31 VKI-I/II-08/20 Phase 1/Phase 2 Clinical Status not specified 3 3 Months 300 2020-09-30
Effects of guided imagery on anxiety, muscle pain and vial signs in patients with COVID-19 Anxiety disorder, Coronavirus disease 19 infection, Myalgia headphone-guided mental imagery training alone, muscle relaxation alone, routine care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Oroumia University of Medical Sciences Iran 2020-05-21 2020-08-10 IR.UMSU.REC.1399.102, IRCT20131112015390N5 Phase Not Applicable Completed 1 2 Months 110 Naser Parizad 2020-09-30
An observational case report to determine the drug evaluation and pharmaceutical care in a critically ill COVID-19 patient Coronavirus disease 19 infection drug evaluation alone Science and Technology Agency of Shandong Province Phase Not Applicable Status not specified 0 1 2020-09-29
Clinical trial of trans sodium crocetinate against COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome anti-coronavirus drug therapy alone, trans sodium crocetinate alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Mashhad University of Medical Sciences Iran 2020-10-22 IR.MUMS.REC.1399.414, IRCT20081019001369N7 Phase 2 Clinical Not yet recruiting 1 30 Hossein Hosseinzadeh, Mohsen Tafaghodi, Zahra Javid Arabshahei 2020-09-30
A phase II clinical trial of PSC-01 in the treatment of hospitalized COVID-19 patients Coronavirus disease 19 infection PSC-01 alone Personalized Stem Cells Inc California Institute of Regenerative Medicine Phase 2 Clinical Planned 0 2020-09-28
Coping methods of stress among frontline Healthcare workers Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Jai Prakash Narayan Apex Trauma Centre India 2020-10-05 CTRI/2020/09/028085 Phase Not Applicable Not yet recruiting 1 200 Dr Ridhima Bhatia, Dr Yudhyavir Brahmachari 2020-09-29
A phase I clinical trial of PSC-01 in the treatment of hospitalized COVID-19 patients Coronavirus disease 19 infection PSC-01 alone Personalized Stem Cells Inc California Institute of Regenerative Medicine US Phase 1 Clinical Not yet recruiting 1 20 2020-09-28
Corona Virus Infection Among Liver Transplant Recipients Coronavirus disease 19 infection Electrochemiluminescence immunoassay (ECLIA) alone, blood sampling alone Assiut University Egypt 2020-09-15 2020-12-31 17300475, NCT04565782 Phase Not Applicable Recruiting 1 3 Months 150 Amal A Mahmoud, MD, Bashir A Fadel, MD, Dr. Nahed A. Makhlouf, Mohamed A Medhat, MD, Mohammed A Medhat, MD, Nahed A Makhlouf, Professor, Nahed Makhlouf, Professor, Rasha O Refaay, Professor 2020-09-29
Identification and Characterization of SARS-CoV-2 Specific CD8 T-Cells in Humans Coronavirus disease 19 infection biological sampling alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute on Aging National Institutes of Health Clinical Center US 2020-10-15 2022-09-01 000140-AG, 10000140, NCT04565067 Phase Not Applicable Recruiting 1 22 Months 120 Julia L McKelvey, R.N., Julia McKelvey, Nan-Ping Weng, M.D. 2020-10-13
COV2Base: A Rare Disease by COVID Study Cognitive disorder, Coronavirus disease 19 infection, Rare disease Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Heart Lung and Blood Institute National Institutes of Health Clinical Center US 2020-10-15 2021-09-01 000091-H, 10000091, COV2Base, NCT04564274 Phase Not Applicable Recruiting 1 10 Months 120000 Beth A Kozel, M.D., Sharon Osgood, M.S., Sharon Osgood, R.N. 2020-10-13
Clinical Correlates of COVID-19 Pandemic in Patients With Functional Movement Disorder (FMD) and Parkinson's Disease (PD) Coronavirus disease 19 infection, Movement disorder, Parkinsons disease Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Neurological Disorders and Stroke National Institutes of Health Clinical Center US 2020-10-15 2021-12-31 000159-N, 10000159, NCT04565080 Phase Not Applicable Recruiting 1 14 Months 150 Mark Hallett, M.D. 2020-10-13
CDFCOV19: Study of Famotidine With Vitamins C and D for Pandemic Coronavirus Coronavirus disease 19 infection Variable regimens including famotidine , vitamin C (Nature Made) , vitamin D3 (Nature Made) Histamine H2 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) US 2020-12-01 2021-07-31 CDFCOV19, NCT04565392, PYKONSULT 201 Phase 4 Clinical Not yet recruiting 1 8 Months 216 Robert E Pyke, MD, PhD, Robert Pyke, MD, PhD 2020-09-29
A Phase II trial with access to its eClinical Cloud Suite to help seek the fastest path to effective treatment for COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome eClinical Cloud Suite alone Asklepion Pharmaceuticals LLC Sureclinical Inc Phase 2 Clinical Planned 0 2020-09-29
Clinical Trial of Efficacy, Safety, and Immunogenicity of Gam-COVID-Vac Vaccine Against COVID-19 in Belarus Coronavirus disease 19 infection Sputnik V alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Gamalei Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation Collaborator IPHARMA, LLC Russia, Russian Direct Investment Fund Belarus 2020-09-28 2021-04-10 04-GAM-COVID-VAC-2020-RB, NCT04564716 Phase 3 Clinical Recruiting 8 6 Months 100 Elena Abdolvand, MD, Irina Reutskaya, MD, Ljudmila Filipenko, MD, Natalia Proputnevich, MD, Nikolay Dosta, MD, Roman Plotnikov, Sergey Pimanov, MD, Svetlana Ionina, MD, Zakhar Kulakovskiy, MD 2020-10-07
The effect of dental pulp mesenchymal stem cells in treatment of corona disease Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia human dental pulp-derived mesenchymal stem cells (intravenous, COVID-19 pneumonia/respiratory distress syndrome), Kerman University of Medical Sciences alone, intubation therapy alone, oxygen mask alone, routine usual treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kerman University of Medical Sciences Iran 2020-09-10 IR.KMU.REC.1399.373, IRCT20140911019125N8 Phase 2/Phase 3 Clinical Recruiting 1 120 Abbas Pardakhty, Alireza Farsinejad, Mehrdad Farrokhnia 2020-10-05
A phase I clinical trial of 1c-SApNP for the treatment of SARS-CoV-2 Coronavirus disease 19 infection S2GdeltaHR2-presenting I3-01v9 self-assembling protein nanoparticle (COVID-19), Ufovax alone COVID19 Spike glycoprotein modulator Ufovax LLC Phase 1 Clinical Planned 0 2020-09-28
A phase III clinical trial Sputnik V for the prevention of covid-19 Coronavirus disease 19 infection Sputnik V alone COVID19 Spike glycoprotein modulator Dr Reddy's Laboratories Ltd, Gamalei Institute of Epidemiology and Microbiology, Russian Direct Investment Fund India Phase 3 Clinical Planned 1 2020-10-05
A clinical trial of NLC-001 for the potential treatment of COVID-19 Coronavirus disease 19 infection NLC-001 alone Todos Medical Ltd Israel Phase Not Applicable Planned 1 2020-09-28
A clinical trial to evaluate the efficacy of gRAD-based test for rapid detection of COVID-19 virus Coronavirus disease 19 infection gRAD-based test alone BioPorto Diagnostics A/S Phase Not Applicable Planned 0 2020-09-28
An Observational Study of Neurological Function After COVID-19 Infection Coronavirus disease 19 infection, Neurological disease MRI alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Neurological Disorders and Stroke National Institutes of Health Clinical Center US 2020-10-15 2022-12-01 000094-N, 10000094, NCT04564287 Phase Not Applicable Recruiting 1 25 Months 100 Avindra Nath, M.D. 2020-10-13
O2matic-COVI: Automatic Oxygen Titration With O2matic to Patients Admitted With COVID-19 and Hypoxemic Respiratory Failure Coronavirus disease 19 infection, Hypoxia, Respiratory failure O2matic alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) HS Hvidovre Hospital The Danish National Advanced Technology Foundation Denmark 2020-04-15 2020-05-31 NCT04565106, O2MATIC-COVID, O2matic-COVI Phase Not Applicable Completed 1 1 Month 16 Ejvind Frausing Hansen, Ove Andersen, PhD 2020-09-29
Cord Blood-Derived Mesenchymal Stem Cells for the Treatment of COVID-19 Related Acute Respiratory Distress Syndrome Coronavirus disease 19 infection, Respiratory distress syndrome mesenchymal stem cell therapy (respiratory distress syndrome), MD Anderson Cancer Center alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) MD Anderson Cancer Center National Cancer Institute US 2020-07-29 2021-04-30 2020-0365, NCI-2020-06741, NCT04565665 Phase 1 Clinical Recruiting 1 9 Months 70 Amanda Olson 2020-09-30
Convalescent Plasma Therapy for COVID-19 Patients Coronavirus disease 19 infection convalescent plasma alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Pakistan 2020-05-01 2020-10-30 LGH008, NCT04565197 Phase 0 Clinical No longer recruiting 1 5 Months 20 Dr. M.Irfan Malik, Muhammad Irfan Malik, FCPS 2020-09-29
A prospective study to evaluate the effect of systemic inflammatory response to SARS-CoV-2 on lopinavir and hydroxychloroquine plasma concentrations Coronavirus disease 19 infection hydroxychloroquine plus lopinavir + ritonavir Swiss National Science Foundation Phase Not Applicable Status not specified 0 92 2020-09-28
DIAL-COVID-19: Transmission of COVID-19 Virus Among Patients and Staff in Dialysis Centers Coronavirus disease 19 infection, Kidney dialysis Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Alessandro Manzoni Hospital Italy 2020-09-21 2021-10-31 DIAL-COVID-19, DIAL-COVID-19, NCT04565522 Phase Not Applicable Not yet recruiting 1 13 Months 5000 PierAngela Presta, MD, Simeone Andrulli, MD 2020-09-29
A Study in Healthy Subjects to Assess Bioavailability (Proportion of a Drug Which Enters the Circulation to Have an Active Effect) of Acalabrutinib Tablet and Proton-pump Inhibitor Effect (Members of a Class of Medications That Inhibits in Gastric Acid Production) for Rabeprazole Coronavirus disease 19 infection, Mantle cell lymphoma, Respiratory failure acalabrutinib alone, acalabrutinib plus rabeprazole Btk tyrosine kinase inhibitor, H+ K+ ATPase inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) AstraZeneca plc PAREXEL International Germany 2020-10-07 2020-11-30 D8223C00005, NCT04564040 Phase 1 Clinical Not yet recruiting 1 1 Month 40 AstraZeneca Clinical Study Information Center, Dr. Rainard Fuhr 2020-09-29
Clinical Trial to Investigate the Efficacy and Safety of NuSepin in COVID-19 Pneumonia Patients Coronavirus disease 19 infection, Viral pneumonia HY-209 (sepsis/ulcerative colitis/Alzheimer's disease), Shaperon alone G-protein coupled bile acid receptor 1 agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Shaperon Inc Romania 2020-09-25 2020-11-30 2020-003107-34, NCT04565379, SHAPERON001 Phase 2 Clinical Recruiting 4 2 Months 60 Catalina Luca, Dr./Prof., Cosmina Magdau, Dr., David Song, Iulian Diaconescu, Dr., Olga Caliman-Sturdza, Dr., Seung-Yong Seong, Dr. 2020-10-01
A clinical study with nasally administered foralumab either alone or in combination with orally administered dexamethasone in Brazil for treatment of coronavirus infection Coronavirus disease 19 infection foralumab (nasal, neurodegenerative diseases), Tiziana alone, dexamethasone plus foralumab (nasal, neurodegenerative diseases), Tiziana CD3 antagonist Tiziana Life Sciences PLC Brazil Phase Not Applicable Planned 1 2020-10-05
Follow-up Study on Pulmonary Function and Lung Radiographic Changes in Rehabilitating COVID-19 Patients After Discharge Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Union Hospital Tongji Medical School Huazhong University Of Science & Technology China 2020-05-01 2020kfyXGYJ019, ChiCTR2000038609 Phase Not Applicable Recruiting 1 300 Heshui Shi, Xiaoyu Han 2020-09-30
Study of Particle Life Sciences Formulation in management of COVID-19 Coronavirus disease 19 infection Particle Life Sciences Formulation Capsules alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) India 2020-09-25 CTRI/2020/09/027938, PLS-SF-09/2020 Phase 3 Clinical Not yet recruiting 1 100 Dr Sagar Mandlik, Dr Yogesh Dound 2020-09-29
Comorbidities And Complications Associated With Covid-19 Infection Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assiut University Egypt 2020-10-15 2023-02-25 COVID 19, NCT04563442 Phase Not Applicable Not yet recruiting 1 28 Months 200 Gamal Mohamed Rabee, Mahmoud Gamal Hussein, Mahmoud Gamal hussein 2020-09-28
SegCov: Follow-up and Rehabilitation of Survivors of Severe Coronavirus Disease 2019 (COVID-19) Infection Coronavirus disease 19 infection cardiopulmonary stress test alone, chest tomography alone, pulmonary function test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo Brazil 2020-06-23 2021-12-31 4047553, NCT04563156, SegCov Phase Not Applicable Recruiting 1 18 Months 100 2020-09-28
A phase III clinical trial of Foistar in the treatment of patients with COVID-19 infection Coronavirus disease 19 infection repurposed camostat mesilate (oral, COVID-19), Daewoong/Institut Pasteur Korea/Korea Institute of Radiological and Medical Sciences alone Serine protease inhibitor, Transmembrane serine protease 2 inhibitor, Trypsin inhibitor Daewoong Pharmaceutical Co Ltd 2020-12-31 Phase 3 Clinical Planned 0 2020-09-25
ACC19: Covid19 Post Treatment Restorative Healthcare Coronavirus disease 19 infection Variable regimens including Agastya rasayana , Chyavanaprash , Dasamoolakatutraya kashaya , Indhukantha kashaya , Kooshmanda rasayana , Vyagriyadhi kashaya Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Indian Medicine and Homoeopathy, Ministry of Health and Family Welfare India 2020-10-01 ACC19, CTRI/2020/09/027916 Phase 2 Clinical Not yet recruiting 1 150 Dr J Clarence Davy, Dr Senthiarasi TM 2020-09-28
The SAFE School Hessen study: Early detection of SARS-CoV-2 (COVID-19) in schools in the state of Hesse, Germany Coronavirus disease 19 infection SARS-CoV-2 antigen test alone Deutsche Forschungsgemeinschaft (DFG), German Federal Ministry of Education and Research Germany 2020-09-16 20-899, DRKS00023091, The SAFE School Hessen study Phase Not Applicable Recruiting 1 1000 Sandra Ciesek, Sebastian Hoehl 2020-09-28
SERO-CoV-OLD: COVID-19 Serology and Immunosenescence Coronavirus disease 19 infection COVID-19 neutralizing antibody test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire D Amiens France 2020-09-18 2021-11-30 NCT04563650, PI2020_843_0079, SERO-CoV-OLD Phase Not Applicable Recruiting 1 14 Months 330 Cédric JOSEPH, MD, Etienne BROCHOT, MD, Frédéric BLOCH, Pr, Jean-Philippe LANOIX, MD, Julien MOYET Julien, MD, Julien MOYET, MD 2020-09-28
SARS-CoV-2 IgG and IgM Serologic Assays Coronavirus disease 19 infection Beckman Coulter immunoassay alone, Roche automated immunoassay alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Henry Ford Health System US 2020-08-14 2021-08-31 13839, NCT04562246 Phase Not Applicable Recruiting 1 12 Months 500 Bernard C Cook, Bernard C Cook, PhD, Bernard Cook, Division Head, Chemistry-Pathology, John Zajechowski, BS 2020-09-29
Tele-yoga for prevention and management of COVID-19 Coronavirus disease 19 infection Tele-yoga alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ministry of Ayush India 2020-10-01 CTRI/2020/09/027915 Phase Not Applicable Not yet recruiting 1 136 Dr Manjunath NK, Dr Nagarathna R 2020-09-28
Surveillance of Bala Vriddhikara Bhava (Factors Responsible for Host Immunity) in Covid-19 Subjects Coronavirus disease 19 infection Balavriddhikara Bhava alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Ayurveda India 2020-09-30 CTRI/2020/09/027917 Phase Not Applicable Not yet recruiting 1 200 Dr Meera K Bhojani 2020-09-30
Role, challenges and opportunities of catholic pastoral care as part of 'spiritual care' in the end-of-life setting and under COVID-19 pandemic conditions Coronavirus disease 19 infection expert interviews alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitätsklinikum Freiburg, Klinik für Palliativmedizin Germany 2020-10-15 444/20, DRKS00022925 Phase Not Applicable Not yet recruiting 1 30 Katharina Seibel 2020-09-29
A randomized, crossover, single-center, single-dose, phase I trial to assess EG-009 in healthy subjects for the potential treatment of COVID-19 pneumonia Coronavirus disease 19 infection EG-009, Shenzhen Evergreen Therapeutics alone Healthy volunteers accepted Shenzhen Evergreen Therapeutics Co Ltd US Phase 1 Clinical Not yet recruiting 1 24 2020-09-29
SEQ-COV-PHYSIO: Physiopathology and Sequelae of COVID-19 Infection Coronavirus disease 19 infection, Viral pneumonia blood test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire D Amiens France 2020-09-22 2021-03-31 NCT04563676, PI2020-843-0096, SEQ-COV-PHYSIO Phase Not Applicable Recruiting 1 6 Months 400 Claire ANDREJAK, Pr, Rachel DESAILLOUD, Pr, Valery Salle, MD 2020-09-28
Seroprevalence of SARS-CoV 2 in Asymptomatic Frontline COVID-19 HCWs Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Pakistan 2020-07-01 2020-10-30 LGH002, NCT04563247 Phase Not Applicable No longer recruiting 1 3 Months 700 Amina Asif, MPhilMicro 2020-10-01
A phase II, randomized, multicenter, double-blind, placebo-controlled trial to evaluate the safety of fostamatinib for the treatment of hospitalized COVID-19 patients Coronavirus disease 19 infection fostamatinib alone National Heart Lung and Blood Institute, Rigel Pharmaceuticals Inc Inova Health Care Services US 2020-09-17 Phase 2 Clinical Recruiting 2 60 2020-09-25
Sustained Immunity to SARS-CoV-2 Coronavirus disease 19 infection RT-PCR alone, immunoassay alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Henry Ford Health System US 2020-06-23 2021-06-30 13978, NCT04562285 Phase Not Applicable Recruiting 1 12 Months 500 Bernard C Cook, Bernard C Cook, PhD, Bernard Coo, John Zajechowski, BS 2020-09-28
A phase I clinical trial of PTX-COVID19-B for the potential treatment of COVID-19 Coronavirus disease 19 infection PTX-COVID19-B alone COVID19 Spike glycoprotein modulator Providence Therapeutics Holdings Inc 2020-12-31 Phase 1 Clinical Planned 0 2020-10-06
DuACT: Study of Oral Administration of Ribavirin and Nitazoxamide Versus Placebo in COVID-19 Coronavirus disease 19 infection nitazoxanide plus ribavirin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Witwatersrand South Africa 2020-12-31 2021-03-31 DUACT-101, DuACT, NCT04563208 Phase 2 Clinical Not yet recruiting 1 3 Months 40 Willem Daniel Francois Venter, 2020-09-29
AMABIE-COVID-19: Assessment of the prediction models to alleviate burden of infectious disease in the emergency department-COVID-19 Coronavirus disease 19 infection Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Japanese Association for Acute Medicine Japan 2020-09-24 AMABIE-COVID-19, UMIN000041893 Phase Not Applicable Recruiting 1 784 Atsushi Shiraishi, Shuta Fukuda 2020-09-28
Safety and Immunogenicity Trial of an Oral SARS-CoV-2 Vaccine (VXA-CoV2-1) for Prevention of COVID-19 in Healthy Adults Coronavirus disease 19 infection VXA-CoV2-1 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Vaxart Inc US 2020-09-30 2021-10-31 NCT04563702, VXA-COV2-101 Phase 1 Clinical Recruiting 1 13 Months 48 Josefina Martinez, Priscilla Trejo, Shaily J Garg, Tami Islam, MPH, Youngjun Kim, MD 2020-10-05
Community Applications of the MindShift App Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression MindShift app alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Windsor Canada, US 2020-09-15 2022-10-31 MINDSHIFT, NCT04562948 Phase Not Applicable Not yet recruiting 2 25 Months 250 Lance M Rappaport, Ph.D. 2020-09-28
Group of patients admitted to the emergency department with COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo Brazil 2020-03-14 30417520.0.0000.0068, 4.228.204, RBR-5d4dj5, U1111-1258-1111 Phase Not Applicable No longer recruiting 1 2500 Julio Flavio Marchini 2020-09-28
Clinical Profile and Outcomes of Coronavirus Disease 19 (COVID-19) Patients Who Underwent Hemoperfusion (HP) in a COVID Referral Hospital: A Descriptive Study Coronavirus disease 19 infection hemoperfusion alone Philippine General Hospital Philippines 2020-04-01 2020-09-30 PHRR200915-002928 Phase Not Applicable Not yet recruiting 1 6 Months Chicki Florette C. Uy, Elizabeth S. Montemayor, Jan Andre S. Montemayor, Jen Adrian S. Montemayor, Sheryll Anne Manalili, Sheryll Anne R. Manalili 2020-09-28
REPAVID-19: Reparixin in COVID-19 pneumonia Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia reparixin (oral tablet, COVID-19 associated pneumonia), Dompe alone CXCR1 chemokine antagonist, CXCR2 chemokine antagonist, IL-8 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dompe Farmaceutici SpA Italy 2020-05-06 2020-001645-40, REPAVID-19, REPAVID-19 Phase 2/Phase 3 Clinical Recruiting 1 159 Flavio Mantelli 2020-09-28
Clinical trial of Favipiravir treatment of patients with COVID-19 Coronavirus disease 19 infection, Viral pneumonia favipiravir alone RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hungary 2020-09-17 2020-002728-35, HUN-AVI-01 Phase 3 Clinical Recruiting 1 150 CRO 2020-09-29
Utility of Medihope as an addon therapy for Covid 19 patients Coronavirus disease 19 infection, Respiratory disorder Medihope alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) India 2020-10-02 CTRI/2020/09/027975 Phase 3 Clinical Not yet recruiting 2 880 Dr Rahul Kunkulol 2020-09-28
Clinical Evaluation of Chyawanprash for the prevention of COVID-19 among Health Care Personnel Coronavirus disease 19 infection Chyawanprash alone, Standard Preventive Regimen alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Central Council for Research in Ayurvedic Sciences India 2020-10-15 CTRI/2020/09/027974 Phase 2 Clinical Not yet recruiting 1 200 Dr Satyendra Kumar Sonkar 2020-09-28
HFNC19LGH: High-Flow Nasal Cannula (HFNC) In COVID-19 Patients Coronavirus disease 19 infection, Respiratory disease, Viral pneumonia high-flow nasal cannula alone, high-flow nasal oxygen therapy alone, prone positioning alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Pakistan 2020-05-01 2020-10-30 HFNC19LGH, LGH004, NCT04560257 Phase Not Applicable Recruiting 1 5 Months 30 Dr. M.Irfan Malik, Muhammad Irfan Malik, FCPS, Sardar Al-Fareed Zafar, Sardar Al-Fareed Zafar, FCPS 2020-10-05
An open-label, prospective, comparative study to evaluate the proposed therapy in adults with mild symptomatic COVID-19 patients receiving the standard treatment of COVID infection Coronavirus disease 19 infection Variable regimens including Ascoril LS , cefixime , ivermectin , montelukast sodium Chloride channel modulator, Leukotriene D4 antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) India 2020-09-22 CTRI/2020/09/027944 Phase 3 Clinical Not yet recruiting 1 30 Dr Anita Saibannavar, Dr Dhananjay Lad 2020-09-28
Single arm study of Itolizumab in the treatment of COVID 19 complication Coronavirus disease 19 infection itolizumab alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Biocon Ltd India 2020-09-26 CTRI/2020/09/027941, ITOLI-C19-04-I-01 Phase 4 Clinical Not yet recruiting 7 Dr Anuja Pandit, Dr Atul Gogia, Dr Mahendran, Dr Rosemari De Souza, Dr Subramanian Loganathan, DrChirag Rathod, DrNilesh Mahale, DrRosemarie De Souza, DrSushant Hiraman Meshram, Sivakumar Vaidyanathan 2020-09-29
Prophylactic study of Ashwagandha and HCQ in health care providers Coronavirus disease 19 infection Ashwagandha (Withania somnifera alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ministry of Ayush India 2020-10-03 CTRI/2020/09/028007 Phase 2 Clinical Not yet recruiting 1 400 Anand More 2020-09-28
The SOAR Study: Sources of a Resilient Mindset in Health Professionals During COVID-19 Coronavirus disease 19 infection off semi-structured interviews alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) La Trobe University Australia 2020-09-23 2020-12-02 ACTRN12620000921987p, The SOAR Study Phase Not Applicable Not yet recruiting 1 2 Months 20 Dr Lydia Brown 2020-09-29
GERIA-COVID: Elucidating the Symptomatic, Explanatory and Prognostic Characteristics of Geriatric Patients Hospitalized for COVID-19 Coronavirus disease 19 infection Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Angers France 2020-03-15 2020-07-31 2020/100, AR20-0087V0, GERIA-COVID, NCT04560608 Phase Not Applicable Completed 1 4 Months 255 Cédric ANNWEILER, MD, PhD 2020-09-29
DETECT Schools: DETECT Schools Study: Understanding the impact of COVID-19 in Western Australian Schools Coronavirus disease 19 infection Enhanced COVID-19 index case response alone, SARS-CoV-2 asymptomatic spot testing alone, Survey-based wellbeing assessments alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Telethon Kids Institute The Department of Health Western Australia Australia 2020-05-29 2020-11-09 ACTRN12620000922976, DETECT Schools, DoH20205875 Phase Not Applicable No longer recruiting 2 5 Months 30000 Ms Derry Simpson, Prof Peter Gething 2020-09-29
Clinical Trial to Evaluate the Efficacy, Immunogenicity and Safety of the Inactivated SARS-CoV-2 Vaccine (COVID-19) Coronavirus disease 19 infection COVID-19 vaccine (inactivated, Vero cells/intramuscular), Beijing Biological Products Institute/National Institute for Viral Disease Control and Prevention of Chinese Center for Disease Control and Prevention alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Laboratorio Elea Beijing Biological Products Institute Co Ltd, China National Biotec Group, The Huesped Foundation Argentina 2020-09-16 2021-12-01 BIBP2020003AR, NCT04560881 Phase 3 Clinical Recruiting 4 14 Months 3000 Eduardo Spitzer, B.Sc., Florencia Cahn, MD, Gabriela Aguirre, MSc, Maria I Figueroa, MD, Pablo Bonvehi, MD, Pedro Cahn, MD, Ricardo Ruttimann, MD 2020-10-03
Dental implants in cleft lip and alveolar patients Cleft palate, Coronavirus disease 19 infection cone beam computed tomography (CBCT) alone, dental implant alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Jamia Millia Islamia India 2020-11-01 CTRI/2020/09/027997 Phase Not Applicable Not yet recruiting 1 30 Dr Rizwana Mallick, Dr Srinivas Gosla Reddy 2020-09-28
Assessment of effect of COVID-19 on fatigue and exercise capacity in patients with Covid-19 treated at a government tertiary care hospital Coronavirus disease 19 infection, Fatigue Fatigue Assessment Scale alone, One Minute Sit to Stand test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) B.Y.L Nair Charitable Hospital India 2020-09-30 CTRI/2020/09/027993 Phase Not Applicable Not yet recruiting 1 75 Anagha Mangaonkar, Dr Chhaya Verma, Sayali Mhatre 2020-09-29
Investigator Initiated Study to Evaluate the Effectiveness and Safety of Thymosin α-1 (Tα1) in Moderate COVID-19 Patients Coronavirus disease 19 infection standard of care alone, thymalfasin alone Thymosin receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Innovative Drug Discovery Inc, Kasturba Hospital India 2020-09-25 CTRI/2020/09/027992, IIT_THY_002_20 Phase 2 Clinical Not yet recruiting 1 20 Dr Adarsh Shetty, Dr Om Shrivastava 2020-09-30
A clinical trial of self-amplifying RNA vaccine (im, COVID-19), Imperial College London to assess the safety and effectiveness of delivering the vaccines directly to the respiratory tract of human volunteers, by inhalation through the mouth Coronavirus disease 19 infection self-amplifying RNA vaccine (im, COVID-19), Imperial College London alone COVID19 Spike glycoprotein inhibitor Imperial College London, University of Oxford National Institute for Health Research (NIHR), United Kingdom Research & Innovation Phase Not Applicable Planned 0 2020-09-24
A clinical trial of AZD-1222 to assess safety and effectiveness of delivering the vaccines directly to the respiratory tract of human volunteers, by inhalation through the mouth Coronavirus disease 19 infection AZD-1222 alone COVID19 Spike glycoprotein modulator Imperial College London, University of Oxford National Institute for Health Research (NIHR), United Kingdom Research & Innovation Phase Not Applicable Planned 0 2020-09-24
SECURADOM: Secure Self-monitoring Through a Combination of Connected Objects: Implementation in COVID-19 Patients Monitored at Home Coronavirus disease 19 infection Withings Sleep device alone, Withings Tensiometer device alone, Withings Thermo device alone, Withings smartwatch device alone, home monitoring alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Withings France 2020-09-14 2021-09-14 2020-A00981-38, NCT04560855, SECURADOM Phase Not Applicable Recruiting 4 12 Months 400 David Campo, PhD, Jean-Louis Pépin, Pr, Yang Rui Yu, PhD 2020-09-28
Investigation of Subsequent and Co-infections Associated With SARS-CoV-2 (COVID-19) Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Methodist Health System US 2020-05-30 2021-05-31 033.PHA.2020.A, NCT04561193 Phase Not Applicable Recruiting 2 12 Months 200 Crystee Cooper, DHEd, Ed Dominguez, MD, Matthew Crotty, PharmD, Paola Gregoire, MS, MBA, Ronda Akins, PharmD 2020-09-25
Evaluation of the COVIDSeq Test in Nasal Swab and Saliva From an Asymptomatic Population Coronavirus disease 19 infection COVIDSeq Test (Illumina, Inc) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Illumina Inc Helix BioPharma Corp US 2020-09-11 2020-12-31 COVD-B07-002, NCT04561102 Phase Not Applicable Recruiting 1 3 Months 2500 2020-09-28
Post COVID Syndrome: Clinical Pattern and Functional Assessment Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assiut University Egypt 2020-12-01 2022-01-01 NCT04561141, POSTCOVID SYNDROME Phase Not Applicable Not yet recruiting 1 13 Months 85 Lamia Hassan Shaban, professor, Mostafa Mahmoud 2020-09-28
Evaluate Safety and Pharmacokinetics of HLX-70 in Healthy Adult Volunteers Coronavirus disease 19 infection HLX-70 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Hengenix Biotech Inc Sanyou Biopharmaceuticals (Shanghai), Shanghai ZJ Bio-Tech US 2020-12-09 2021-09-18 HLX70-001US-255086, NCT04561076 Phase 1 Clinical Not yet recruiting 1 9 Months 24 Esther Yoon, MD, Sherry Xu 2020-10-12
Large vessel thrombosis in patients with COVID-19 Coronavirus disease 19 infection, Thrombosis University of Sulaimani Iraq 2020-01-01 2020-08-01 ChiCTR2000038537 Phase Not Applicable No longer recruiting 1 7 Months 7 Fahmi Hussein Kakamad, Hawbash Mohammed-Amin Rahim 2020-09-29
A study of neurological damage in patients recovering from novel coronavirus pneumonia (COVID-19) Coronavirus disease 19 infection, Viral pneumonia Magnetic resonance examination alone Healthy volunteers accepted Anhui Provincial Hospital China ChiCTR2000038471 Phase Not Applicable Recruiting 1 160 Jieping Lu, Wei Xiong, Xiaoling Ding 2020-09-25
Depression, Anxiety and SARS-CoV-2 (Covid-19) Phobia in Post-stroke Patients Anxiety disorder, Coronavirus disease 19 infection, Depression, Phobia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fatih Sultan Mehmet Training and Research Hospital Turkey 2020-06-01 2020-08-10 FSMEAH-KAEK 2020/41, NCT04560413 Phase Not Applicable Completed 2 2 Months 77 Arzu Atici, MD, Duygu Silte Karamanlioglu, MD, Feyza Unlu Ozkan, Assoc Prof, Gulcan Ozturk, MD, Ilknur Aktas, Prof, Pinar Akpinar, Assoc Prof 2020-10-01
Study to Evaluate the Efficacy and Safety of EG-HPCP-03a Compared to DEX in Patients With COVID-19 Pneumonia Coronavirus disease 19 infection, Respiratory disease, Viral pneumonia Standard of care alone, EG-HPCP-03a plus dexamethasone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Evergreen Therapeutics Inc 2020-12-31 2021-12-31 HPC-EG-009A-2.1, NCT04561180 Phase 2 Clinical Not yet recruiting 0 12 Months 96 2020-10-12
A clinical trial of Newsight Imaging’s revolutionary spectral device for the diagnosis of Covid-19 Coronavirus disease 19 infection Newsight Imaging’s revolutionary spectral device alone Newsight Imaging Ltd, Sheba Medical Center Phase Not Applicable Recruiting 0 2020-09-24
COVER HCW: COVID-19 Prophylaxis South Africa Coronavirus disease 19 infection, Respiratory disease nitazoxanide alone, sofosbuvir + daclatasvir alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Witwatersrand South Africa 2020-12-31 2021-07-31 COVER HCW, EZ-SS-025, NCT04561063 Phase 2 Clinical Not yet recruiting 2 7 Months 1950 Willem Daniel Francois Vente 2020-09-29
A Study Looking at the Safety and Effectiveness of a COVID-19 Vaccine Plus Adjuvant in South African Adults Coronavirus disease 19 infection Matrix M plus NVX-CoV2373 COVID19 Spike glycoprotein modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Novavax Inc Bill & Melinda Gates Foundation South Africa 2020-08-30 PACTR202009726132275 Phase 2 Clinical Recruiting 6 2904 Gary Albert, Shabir Madhi, Vivek Shinde 2020-09-25
A clinial trial of repurposed azelastine (COVID-19), CEBINA for the treatment of COVID-19 Coronavirus disease 19 infection repurposed azelastine (COVID-19), CEBINA alone Histamine H1 receptor antagonist CEBINA GmbH Phase Not Applicable Planned 0 2020-09-24
TC19LGH: Tocilizumab in COVID-19 Lahore General Hospital Coronavirus disease 19 infection tocilizumab (intravenous), Roche/Chugai alone IL-6 receptor antagonist, IL-6 receptor modulator Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Pakistan 2020-05-01 2020-10-30 LGH001, NCT04560205, TC19LGH Phase 1 Clinical Recruiting 1 5 Months 50 Dr. M.Irfan Malik, Associate Professor, Muhammad Irfan Malik, Muhammad Irfan malik, Sardar Al-Fareed Zafar 2020-09-25
Lung Sequelae Post COVID-19 Survivors Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Tengku Ampuan Afzan Malaysia 2020-09-30 2021-03-30 56268, NMRR-20-2017-56268, PCOV2020 Phase Not Applicable Not yet recruiting 1 6 Months 40 Dr Tan Sin Nee 2020-09-25
Respiratory Function in COVID-19 Survivors Coronavirus disease 19 infection, Respiratory disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) MAHSA University, Universiti Malaysia Sarawak, Universiti Teknologi Mara Malaysia 2020-11-01 2023-10-31 56330, NMRR-20-2011-56330 Phase Not Applicable Not yet recruiting 2 36 Months 386 A/Prof Dr Chai Chee Shee, Dr Benedict Sim, Prof Mohammed Fauzi Abdul Rani 2020-09-25
COVID-19 vaccine visitors Coronavirus disease 19 infection Malaysia 2020-10-15 2021-10-15 56433, NMRR-20-2016-56433 Phase Not Applicable Status not specified 1 12 Months NOR AZIZAH BINTI MOHAMAD NAZRI, Rabiahtul Adawiyah binti Egar 2020-09-25
Evaluation of a COVID-19 Pneumonia CXR AI Detection Algorithm Coronavirus disease 19 infection, Viral pneumonia Chest X-Ray AI Neural Network (RadGen SARS-CoV2 Detection System) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ensemble Group Holdings Hong Kong 2020-03-01 2020-12-31 EN-092020, NCT04561024 Phase Not Applicable No longer recruiting 1 10 Months 4000 2020-09-25
Malaysia I-Share: International Sexual Health and Reproductive (ISHARE) Health during COVID-19: Malaysian Perspective Coronavirus disease 19 infection, Reproductive disorder Institute for Public Health Malaysia 2020-09-19 2023-06-30 55791, Malaysia I-Share, NMRR-20-1998-55791 Phase Not Applicable Status not specified 1 33 Months NORHAFIZAH BTE SAHRIL, Prof. Dr. Low Wah Yun 2020-09-25
FMAB: Body Weight Regulation, Disordered Eating Behaviour, and Experiences of Sexual Harassment in Female Martial Art Athletes Coronavirus disease 19 infection, Eating disorder Healthy volunteers accepted, Female, Adolescents (13-17 yrs), Young Adults (18-44 yrs) Norwegian School of Sport Sciences Ostfold University College, University of Oslo Norway 2020-09-10 2020-12-31 20/00378, FMAB, NCT04559542 Phase Not Applicable Recruiting 1 3 Months 200 Jorunn Sundgot-Borgen, PhD, Professor Jorunn Sundgot-Borgen, Therese F Mathisen, Phd 2020-09-24
The Role of CT Chest Scan in the Pre-anesthetic Assessment of Suspected or Confirmed COVID-19 Patients Coronavirus disease 19 infection, Viral pneumonia Multi-slice CT scan machine alone, Non-enhanced chest CT scan alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tanta University Saudi Arabia 2020-03-01 2020-09-01 CHEST CT SCAN IN COVID-19, NCT04560530 Phase Not Applicable Completed 1 6 Months 76 MOHAMMED FAWZI ALI ABOSAMAK 2020-09-28
A Phase I/IIa clinical trial of K-NK-ID101 in COVID-19 Coronavirus disease 19 infection K-NK-ID101 alone Kiadis Pharma BV Phase 1/Phase 2 Clinical Planned 0 2020-09-24
Evaluation of the COVIDSeq Test in Saliva Specimens From Illumina Personnel Coronavirus disease 19 infection COVIDSeq Test alone, Illumina personnel (Illumina, Inc) alone, saliva sampling alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Illumina Inc Helix BioPharma Corp US 2020-07-13 2020-12-31 COVD-B07-001, NCT04561089 Phase Not Applicable Recruiting 3 5 Months 2000 2020-09-25
RC19LGH: Remdesivir in COVID-19 Lahore General Hospital Coronavirus disease 19 infection remdesivir (Remidia) alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Pakistan 2020-06-01 2020-11-30 LGH003, NCT04560231, RC19LGH Phase 0 Clinical Recruiting 1 6 Months 30 Dr. M.Irfan Malik, Muhammad Irfan Malik, FCPS, Sardar Al-Fareed Zafar, FCPS 2020-09-26
A case-report study evaluating a pediatric inflammatory multisystem syndrome patient with central nervous system involvement and hypocomplementemia following SARS-COV-2 infection Central nervous system disease, Coronavirus disease 19 infection, Inflammatory disease, Kawasaki disease IVIG plus methylprednisolone Male Rambam Health Care Campus Phase Not Applicable Status not specified 0 1 2020-09-25
Biomodulin T in a long-lived population at high risk of COVID-19 infection Coronavirus disease 19 infection Biomodulin T alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Center for Biopreparations (BIOCEN) Ministerio de Salud Publica Cuba 2020-09-21 2020-12-31 GEC2020BMT029, RPCEC00000335 Phase Not Applicable Not yet recruiting 1 3 Months Liliam Rodriguez Rivera, Mary Carmen Reyes Zamora 2020-09-25
PROUDEST: Effects of COVID-19 on pregnancy, childbirth, puerperium, neonatal period and child development: prospective, multicenter cohort study Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Hospital Regional da Asa Norte, University Hospital of Brasilia Brazil 2020-07-01 4.055.854, CAAE: 32359620.0.0000.5558, PROUDEST, RBR-65qxs2, U1111-1253-5244 Phase Not Applicable Recruiting 1 1200 Geraldo Magela Fernandes, Lizandra Paravidine Sasaki, Lícia Maria Henrique da Mota 2020-09-25
An expanded access program to evaluate the efficacy of Zofin in the treatment of COVID-19 patients Coronavirus disease 19 infection Zofin alone, steroids alone, Zofin plus hydroxychloroquine Organicell Regenerative Medicine Phase Not Applicable Status not specified 0 9 2020-09-24
The effect of MMR vaccine in preventing COVID disease 19 Coronavirus disease 19 infection, Measles virus infection, Mumps virus infection, Respiratory tract infection, Rubella virus infection measles/mumps/rubella vaccine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ahvaz University of Medical Sciences Iran 2020-11-19 IR.AJUMS.REC.1399.361, IRCT20200802048266N1 Phase 3 Clinical Not yet recruiting 1 323 Muhammad Badavi, Souri Heidari 2020-09-25
The effect of giving a Drug to block nerves supplying Kidneys to reduce Blood loss during Surgery for removal of Kidney Stones Bleeding, Coronavirus disease 19 infection paravertebral block alone, Variable regimens including fentanyl , glycopyrrolate , isoflurane , midazolam hydrochloride , nitrous oxide , oxygen , propofol, AstraZeneca/Fresenius , ropivacaine , vecuronium , vecurronium Benzodiazepine receptor agonist, Sodium channel inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Rajarajeswari Medical college and Hospital India 2020-10-15 CTRI/2020/09/027909 Phase 2 Clinical Not yet recruiting 1 50 Dr Rashmi 2020-09-29
Evaluation of effects of eucalyptus tablets on the process of Covid-19 disease Coronavirus disease 19 infection eucalyptus soft oral capsule (Barij Essential Oil Company) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Iran University of Medical Sciences Iran 2020-09-22 IR.IUMS.REC.1399.534, IRCT20200913048701N1 Phase 3 Clinical No longer recruiting 1 50 Dr Fateme Tajikrostami, Dr. Seyed Abbas Motavlian, Hossein Shirazi 2020-10-04
RCT, Double-Blind, Placebo to Evaluate the Effect of Zinc and Ascorbic Acid Supplementation in COVID-19 Positive Hospitalized Patients in BSMMU Coronavirus disease 19 infection, Hypoxia, Respiratory failure standard treatment alone, ascorbic acid plus zinc gluconate Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Bangabandhu Sheikh Mujib Medical University Bangladesh 2020-10-01 2021-09-01 BSMMU 2020, NCT04558424 Phase Not Applicable Not yet recruiting 1 11 Months 50 Shohael Mahmud Arafat, FCPS, elora sharmin, MD, sharmin 2020-09-25
NaPro: COVID-19 Study on natural protection against SARS-CoV2 reinfections Coronavirus disease 19 infection biological sampling alone University Hospital, Bonn Deutsche Forschungsgemeinschaft (DFG), German Federal Ministry of Education and Research, Ministerium für Arbeit, Gesundheit und Soziales NRW Germany 2020-09-30 DRKS00023113, Lfd. Nr. 372/20, NaPro Phase Not Applicable Not yet recruiting 2 1250 Hendrik Streeck 2020-09-25
COVID-19 Amyotrophic Lateral Sclerosis (ALS) Registry Coronavirus disease 19 infection, Motor neurone disease Variable regimens including albuterol , dextromethorphan hydrobromide + quinidine sulfate (oral, pseudobulbar affect/ diabetic peripheral neuropathic pain), Avanir Pharmaceuticals , edaravone , riluzole Cytochrome P450 2D6 inhibitor, Metabotropic glutamate receptor 1 antagonist, NMDA receptor antagonist, Nicotinic acetylcholine receptor antagonist, Opioid receptor sigma agonist 1, Sodium channel inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Atrium Health US 2020-10-15 2024-04-30 AH-NSI-COVID19-ALS, NCT04559009 Phase Not Applicable Not yet recruiting 1 42 Months 100 Allison Newell-Sturdivant, MSN, BSN, Erica Gowan, Urvi Desai, MD 2020-09-24
Seroconversion in COVID-19 Recovered Population Coronavirus disease 19 infection serum sampling alone Pakistan 2020-07-01 2020-10-30 LGH006, NCT04558385 Phase Not Applicable No longer recruiting 1 3 Months 275 Amina Asif, MPhilMicro 2020-09-25
A Study To Evaluate The Efficacy And Safety Of a Novel Niclosamide Suspension Formulation For COVID-19 (Niclonex) Coronavirus disease 19 infection niclosamide (suspension, COVID-19), Imuneks Farma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Imuneks Farma Ilaç Sanayi Ve Ticaret AS Turkey 2020-10-08 2021-02-14 NCT04558021, NOV2020/01930 Phase 3 Clinical Recruiting 9 4 Months 200 Aydin Erenmemisoglu, Prof.Dr., Ayse O Mete, Dr., Ayşe Ö Mete, Dr., İlkay Karaoglan, Prof. Dr. 2020-10-13
COVID-19 and Lactating Mothers Coronavirus disease 19 infection biological sampling alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Rochester National Institute of Allergy and Infectious Diseases, New York University US 2020-07-02 2021-04-01 3U01AI131344-04S1, NCT04558320, STUDY00004889 Phase Not Applicable Recruiting 1 9 Months 100 Kirsi Jarvinen-Seppo, Miranda Klein 2020-09-25
Methyl19LGH: Methylprednisolone in COVID-19 Patients Coronavirus disease 19 infection, Lung disease dexamethasone alone, methylprednisolone (Pfizer) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Pakistan 2020-05-01 2020-10-30 LGH005, Methyl19LGH, NCT04559113 Phase 2 Clinical Recruiting 1 5 Months 200 Dr. M.Irfan Malik, Muhammad Irfan Malik, FCPS, Muhammad Irfan malik, FCPS, Sardar Al-Fareed Zafar, FCPS 2020-09-25
T2B! immunity after SARS-CoV-2 Coronavirus disease 19 infection The Netherlands Organisation for Health Research and Development Netherlands 2020-09-09 2022-07-01 METC2020_194, NL8900 Phase Not Applicable Not yet recruiting 1 21 Months 900 Luuk Wieske 2020-09-24
Anxiety and Depression Among Pregnant Women During COVID-19 Pandemic Anxiety disorder, Coronavirus disease 19 infection, Depression Healthy volunteers accepted, Female Assiut University Egypt 2020-10-31 2021-06-30 ADCOVID, NCT04558749 Phase Not Applicable Not yet recruiting 1 8 Months 150 Ahmed Mohamed Abbas 2020-09-24
Pilot Study of a Brief, Scaleable Intervention for Coronavirus (COVID-19) Mental Health Sequelae in College Students Coronavirus disease 19 infection Dialectical Behavioral Therapy (DBT) Skills alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rutgers University US 2020-09-12 2020-12-15 NCT04558411, PRO2020002008 Phase Not Applicable Recruiting 1 3 Months 150 Evan Kleiman, Ph.D., Shireen Rizvi, Ph.D. 2020-09-24
Evaluation of Physical Activity and Quality of Life of Patients With Type 1 Diabetes Mellitus During the Covid-19 Pandemic Coronavirus disease 19 infection, Insulin dependent diabetes Online Survey alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Gazi University Turkey 2020-09-18 2020-12-18 91610558-604.01.02, NCT04558645 Phase Not Applicable Recruiting 1 3 Months 70 Füsun BALOŞ TÖRÜNER, Prof, Meral BOŞNAK GÜÇLÜ, Prof, Zeliha ÇELİK, Zeliha ÇELİK, MSc 2020-09-30
HEIDI-BP-HW: Evaluation of Two Eating Disorders Prevention Interventions in At-Risk Female Students With Body Dissatisfaction Coronavirus disease 19 infection, Eating disorder Body Project (BP) alone, Healthy Weight Program (HW) alone Healthy volunteers accepted, Female, Young Adults (18-44 yrs) School of Health Sciences Geneva France 2020-12-01 2022-02-28 99021, HEIDI-BP-HW, NCT04558073 Phase Not Applicable Not yet recruiting 1 15 Months 90 Isabelle Carrard, PhD, Sophie Bucher Della Torre, PhD 2020-09-24
Impact of a Hybrid Medical Care Model in the Rheumatoid Arthritis Patient-reported-outcomes Measures: A Non-inferiority Study Coronavirus disease 19 infection, Rheumatoid arthritis Alternating face-to-face medical visits and video medical consultations alone, Face-to-face medical visits alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto Nacional de Ciencias Medicas y Nutricion Mexico 2020-10-01 2022-05-31 IRE-3438 20221, NCT04558905 Phase Not Applicable Not yet recruiting 1 20 Months 156 Virginia Pascual Ramos 2020-09-24
Nasal Irrigation to Reduce COVID-19 Morbidity Coronavirus disease 19 infection Nasal lavage alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Augusta University US 2020-09-24 2020-12-31 1603291, NCT04559035 Phase Not Applicable Recruiting 1 3 Months 200 2020-09-27
Genosvid Diagnostic Test for Early Detection of COVID-19 Coronavirus disease 19 infection GENOSVID alone, exhaled breath sampling alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Gadjah Mada Indonesia 2020-04-01 2020-12-31 1.6/2020, NCT04558372 Phase Not Applicable Recruiting 8 9 Months 1543 Akhmad Rusly, MD(Surgeon), MARS, Amalia Setyati, MD(Paed), Antonia M.I. Saktiawati, MD, PhD, Asep S, MD(Anesthesiologist), Budi Pranowo, MD(Paed), MSc, Dewi Indiastari, MD(Internist), Dian K. Nurputra, MD(Paed), M.Sc, Ph.D, Diana Septiyanti, MD(Pulm), PhD, FAPSR, Kuwat Triyana, Prof, Dr.Eng, MSi., Tarsisius Glory, MD, MPH, Theresia Lindawati, MD, Sp.F, Vini Sagita, MD, MPH 2020-09-28
Long-term Characterization of Patients With Severe/Critical Infection by COVID-19 Virus Coronavirus disease 19 infection 6 minute walk test alone, chest radiography alone, spirometry alone, thoracic computed tomography scan alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundacion Clinica Valle del Lili Colombia 2020-10-01 2021-10-01 1631 COVID-LFT, NCT04559100 Phase Not Applicable Not yet recruiting 1 12 Months 112 Fernandez, Sangiovanni 2020-09-24
Personalized Electronic Record Supported Optimization When Alone for Patients With Hypertension- Pilot Study for Remote Medical Management of Hypertension During the COVID-19 Pandemic Coronavirus disease 19 infection, Hypertension Blood pressure monitoring alone, Standard home blood pressure monitor alone, amlodipine alone Calcium channel inhibitor L-type Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Queen Mary University of London Closed Loop Medicine Ltd, Technology Strategy Board UK 2020-09-30 2021-07-31 283209, NCT04559074 Phase 4 Clinical Not yet recruiting 2 10 Months 1000 CVC CTU, David Collier 2020-09-24
The Effectivity and Safety of Favipiravir Compared to Oseltamivir as Adjuvant Therapy for COVID-19 Coronavirus disease 19 infection comorbid therapy alone, oxygen therapy alone, symptomatic antipyretic drug treatment alone, Variable regimens including azithromycin , chloroquine phosphate , favipiravir , hydroxychloroquine , levofloxacin , sulphur-based chloroquine , vitamin C DNA gyrase inhibitor, RNA polymerase inhibitor, Topoisomerase IV inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Indonesia Indonesia 2020-04-16 2020-10-30 20-04-0455, NCT04558463 Phase 3 Clinical Recruiting 1 6 Months 100 Cleopas M Rumende, MD, PhD, Dante S Harbuwono, MD, PhD 2020-09-24
The Relationship Between COVID-19 and Autoimmune Diseases, Lessons From Practice Autoimmune disease, Coronavirus disease 19 infection ClinAmygate Egypt 2020-09-22 2020-10-30 NCT04558203, PR0014 Phase Not Applicable Recruiting 1 1 Month 450 Emad R Issak, MD 2020-09-25
COVID-Impact: 'Psychological IMPACT of COVID-19 on AP-HP Staff' Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-06-12 2020-12-31 APHP200555, COVID-Impact, NCT04558437 Phase Not Applicable Recruiting 1 6 Months 20000 Antoine PELISSOLO, MD-PhD, Isabelle Vivaldo, Pierre WOLKENSTEIN, MD-PhD, Pierre-André Natella, PharmD 2020-09-24
Low-Dose Tenecteplase in Covid-19 Coronavirus disease 19 infection, Lung embolism Variable regimens including enoxaparin sodium , heparin , tenecteplase Low molecular weight heparin, Tissue plasminogen activator stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Cedars-Sinai Medical Center US 2020-09-08 2022-06-30 ML42522, NCT04558125 Phase 4 Clinical No longer recruiting 1 21 Months 45 Victor E Tapson, MD 2020-09-24
OBS COVID: Spanish Registry of Pregnant Women With COVID-19 Coronavirus disease 19 infection, Septic shock, Viral pneumonia PCR based screening program alone Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Asian Ancestry, African Ancestry, Japanese Ancestry Hospital Puerta de Hierro Majadahonda Hosp Univ & Politecn La Fe, Hospital General Universitario Gregorio Marañon, Hospital Universitario 12 de Octubre, La Paz University Hospital (Madrid) Spain 2020-03-01 2021-03-31 55/20, COV20/0021, NCT04558996, OBS COVID Phase Not Applicable Recruiting 1 13 Months 3000 Maria Luisa De la Cruz Conti, PhD, Oscar M Martinez Perez, Epidemiologist, Oscar M Martinez Perez, MD 2020-09-24
CARTESIAN: Covid-19 Effects on Arterial Stiffness and Vascular Aging Coronavirus disease 19 infection, Vascular disease early vascular aging tests alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris INSERM France 2020-09-30 2032-06-30 20.07.24.57438, APHP200762, APHP200762, CARTESIAN, NCT04558450 Phase Not Applicable Not yet recruiting 4 141 Months 360 Athanase BENETOS, PhD, David MONTAIGNE, PUPH, Hakima MANSEUR, MSc, Jérémy BELLIEN, PUPH, Pierre BOUTOUYRIE, MD PHD, Pierre BOUTOUYRIE, PUPH, Rosa Maria BRUNO, MD 2020-09-29
Feasibility of Rapid COVID-19 Testing in Disadvantaged Populations Coronavirus disease 19 infection Community-driven letter mailing alone, Community-driven texting alone, Rapid SARS-CoV-2 testing alone, Real-time polymerase chain reaction assay alone Healthy volunteers accepted Mayo Clinic, Minnesota US 2020-06-03 2021-12-01 20-004046, NCT04558307 Phase Not Applicable Recruiting 2 17 Months 1000 LaPrincess C Brewer, MD, MPH 2020-09-25
An observational, retrospective, cohort study to compare ribavirin therapy with supportive therapy for patients with severe coronavirus disease 2019 (COVID-19) only Coronavirus disease 19 infection ribavirin alone, supportive care alone Fudan University, Huazhong University of Science and Technology Phase Not Applicable Status not specified 0 115 2020-09-30
CONFIDENT: Efficacy of Convalescent Plasma in Patients With COVID-19 Treated With Mechanical Ventilation Coronavirus disease 19 infection, Multiple organ failure, Respiratory failure, Viral pneumonia convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Liege Belgium Health Care Knowledge Centre Belgium 2020-09-01 2022-09-01 2020-003102-31, CONFIDENT, NCT04558476 Phase 2 Clinical Recruiting 16 24 Months 500 Alexander Dumoulin, MD, Axelle Bertand, Benoit Misset, MD,PhD, Benoît Misset, PhD, David Grimaldi, MD, Elisabeth De Waele, PhD, Emmanuel Van Der Hauwaert, MD, Eric Hoste, MD, Isabelle Michaux, PhD, Michaël Piagnerelli, MD, Misset Benoit, Professor, Nathalie De Mey, MD, Philippe Jorens, MD, Pierre François Laterre, MD, Stefaan Vandecasteele, MD, Stoffel Lamote, MD, Stéphane De Wit, PhD, Vincent Fraipont, MD, Walter Swinnen, MD 2020-09-24
A phase III trial to evaluate DWRX-2003 for the treatment of patients with COVID-19 Coronavirus disease 19 infection repositioned niclosamide (refractory lung disease/COVID-19), Daewoong Pharmaceutical/Institut Pasteur Korea alone Daewoong Pharmaceutical Co Ltd, Mankind Pharma Limited Phase 3 Clinical Planned 0 2020-09-28
A phase II trial to evaluate DWRX-2003 for the treatment of patients with COVID-19 Coronavirus disease 19 infection repositioned niclosamide (refractory lung disease/COVID-19), Daewoong Pharmaceutical/Institut Pasteur Korea alone Daewoong Pharmaceutical Co Ltd, Mankind Pharma Limited Phase 2 Clinical Planned 0 2020-09-28
A clinical trial of T-cell-targeted peptide epitope vaccine for the treatment of COVID-19 Coronavirus disease 19 infection T-cell-targeted peptide epitope vaccine (gold nanoparticle, COVID-19), Emergex alone Emergex Vaccines Limited 2020-12-31 Phase Not Applicable Planned 0 2020-10-05
Effects of a Face Mask on Oxygenation During Exercise Coronavirus disease 19 infection Cloth face mask alone, Disposable face mask alone, Progressive step-exercise cycling test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Saskatchewan Canada 2020-09-14 2020-11-10 2201, NCT04557605 Phase Not Applicable Recruiting 1 1 Month 12 Keely Shaw, MSc, Philip Chilibeck, Ph.D., Philip Chilibeck, PhD 2020-09-24
Brief Informational Intervention for COVID-19 Misinformation Prophylaxis Coronavirus disease 19 infection Brief informational infographic alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Indiana University Indiana Clinical and Translational Sciences Institute (CTSI) US 2020-10-31 2021-02-28 INDIANA_CTSI_AGLEY_2020, NCT04557241 Phase Not Applicable Not yet recruiting 1 4 Months 1000 Jon Agley, PhD, MPH 2020-09-24
DEPARTS: Complicated Grief in ICU in the Aftermath of COVID-19 Coronavirus disease 19 infection questionnaire alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire D Amiens Centre Hospitalier Regional Universitaire de Lille, Hospital Boisguillaume France 2020-09-01 2022-09-30 DEPARTS, NCT04554264, PI2020_843_0071 Phase Not Applicable Recruiting 1 25 Months 160 Anne Sophie MOREAU, MD, Axel BASTIEN, MD, Deborah BOYER, MD, François THOMAS, MD, Yoann Zerbib, Yoann Zerbib, MD 2020-09-24
Nurse-led Alcohol Brief Intervention Plus Mobile Personalized Chat-based Support on Reducing Alcohol Use in University Students Alcoholism, Coronavirus disease 19 infection 12-page health warning leaflet alone, AUDIT score interpretation sheet adapted from the Department of Health of Hong Kong alone, Alcohol brief intervention alone, General health through IM Apps alone, Real-time chat-based support through IM Apps alone, Regular messages through Instant Messaging (IM) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The University of Hong Kong Hong Kong 2020-09-30 2022-11-30 CHAT-BASED ABI (UNISTUDENTS), NCT04025151 Phase Not Applicable Not yet recruiting 1 26 Months 770 Siu Long Chau, PhD 2020-09-28
TREAT-MS: Traditional Versus Early Aggressive Therapy for Multiple Sclerosis Trial Coronavirus disease 19 infection, Multiple sclerosis Early Aggressive Therapy alone, Traditional Therapy alone, Variable regimens including alemtuzumab , cladribine , dimethyl fumarate , diroximel fumarate , fingolimod , glatiramer acetate , interferon beta-1a, Biogen , interferon beta-1b, Novartis , natalizumab , ocrelizumab , ozanimod , peginterferon beta-1a (multiple sclerosis), Biogen , rituximab , siponimod fumarate , teriflunomide Adenosine deaminase inhibitor, B-lymphocyte antigen CD20 inhibitor, CD52 antagonist, Cannabinoid receptor antagonist, Cell adhesion molecule inhibitor, Dihydroorotate dehydrogenase inhibitor, Integrin alpha-4/beta-1 antagonist, Interferon beta ligand, Kelch like ECH associated protein 1 modulator, Nuclear erythroid 2-related factor 2 stimulator, Sphingosine-1-phosphate receptor-1 agonist, Sphingosine-1-phosphate receptor-1 modulator, Sphingosine-1-phosphate receptor-3 modulator, Sphingosine-1-phosphate receptor-4 modulator, Sphingosine-1-phosphate receptor-5 agonist, Sphingosine-1-phosphate receptor-5 modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Johns Hopkins University Patient Centered Outcome Research Institute US 2018-05-02 2023-08-01 IRB00143534, NCT03500328, TREAT-MS Phase Not Applicable Recruiting 50 63 Months 900 Aaron Miller, MD, Ahmed Obeidat, MD, Amy Harmala, LPN, Andrew Russo, Andrew Solomon, MD, Angela Aungst, Angela Whitmire, Anna Vaeth, Annette F Okai, MD, Carlo Tornatore, MD, Carolina Ionete, MD, Cedars-Sinai MS Research Coordinator, Chelsie Derr, Claire Riley, MD, Dakota Williams, MS, Daniel Harrison, MD, Deborah Lockridge, RN, BSN, MSCN, CCRC, Dennis Dietrich, MD, Derek Haase, Derrick Robertson, MD, Dunia Gragui, Edward J Fox, MD, PhD, FAAN, Elisa McGee, Ellen M Mowry, MD, MCR, Ellen M. Mowry, MD, MCR, Emma Mathews, Emmanuelle L Waubant, MD, PhD, Eric C. Klawiter, MD, MSc, Eunice Travis, Evanthia Bernitsas, MD, Gabriel Pardo, MD, Geeta A Ganesh, MD, MPH, Geoffrey Eubank, MD, Gloria Rodriguez, Gloria von Geldern, MD, Hannah Voss, Ingrid Loma-Miller, MD, Irina Radu, MD, James Wymer, MD, FAAN, Jane Low, MPA, CCRC, Jason Silversteen, DO, Jeanette Lee, Jennifer S. Graves, MD, PhD, MAS, Jennifer Steshyn, Jessica Sagen, MA, Jill Cramer, MD, John W Rose, MD, Ka Ho Wong, Kaho Onomichi, Katelyn Hilz, Kathleen Greenbaum, MSN, RN, CCRC, CDE, Kathy Wilkinson, RN, BSN, OCN, CCRP, Katie Doane, Katie Lyons, RN, BSN, CCRC, Kehaunani Hubbard, Kendall Curtis, Kerry Howard, RN, MSCN, Kerry Naunton, RN, MSCN, CCRC, Krupa Pandey, MD, Lana Zhovtis Ryerson, MD, Laura Armstrong, LPN, Lee Ifhar, MSc, Leticia Tornes, MD, Lexie Hackman, Lindsey Maassel, MS, MA-R, Lisa Schmidt, LPN, Lucy Ng, MA, CCRC, Lupe Zuniga-Estrada, Lynn Wheeler, MS, CCRC, Mary Fetter, Mason Kruse-Hoyer, MD, Megan Esch, MD, Melody Hackett, Michael Hadden, MPA, CCRP, Michael Ko, MD, Micki Moore, Miryam Palomino, Nancy Sicotte, MD, Peiqing Qian, MD, Ram Narayan, MD, Rana K Zabad, MD, FAAN, Roman Kassa, MD, Rosemarie R. Baligod, RN, BSN, Sabeen Lulu, MD, Sadio Abdul, Samantha O'Dell, Samantha Villa, Samantha Wang, RN, BSN, Sandra Cassard, ScD, Sara Qureshi, MD, Scott D Newsome, DO, Scott D. Newsome, DO, Sharon Lynch, MD, Siddharama Pawate, MD, Stacey Lent, CCRC, Stanley Cohan, MD, PhD, Susan Emrich, MBA, Susan Filomena, Tiffany Ruppert, CCRP, Troy Desai, MD, Uk Sok Shin, Victoria Hope, W. Oliver Tobin, MB, BCh, BAO, PhD, William Kilgo, MD, William Meador, MD, Yanet Babcock, Yang Mao-Draayer, MD, PhD, Yuriko Courtney, CCRC 2020-10-07
CLARITY IBD: Impact of biological therapy on SARS-CoV-2 infection and immunity in patients with inflammatory bowel disease Coronavirus disease 19 infection, Inflammatory bowel disease Exeter home finger prick test kit alone, Roche Elecsys assay alone, infliximab alone, vedolizumab alone Integrin alpha-4/beta-7 antagonist, MAdCAM inhibitor, TNF alpha ligand inhibitor, TNF binding agent Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Royal Devon & Exeter Healthcare NHS Trust F Hoffmann-La Roche AG, Roche Holding AG UK 2020-05-30 2021-10-08 CLARITY IBD, CPMS 46188, IRAS 283251, ISRCTN45176516, RDE CLARITY 2102102 Phase Not Applicable Not yet recruiting 1 16 Months 6970 Ms Bewshea, Prof Tariq Ahmad 2020-09-24
COVID-NA: Changes in emergency department utilitzation during the COVID-19 pandemic Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Charite Universitaetsmedizin Berlin Germany 2020-03-01 COVID-NA, DRKS00023117, EA1/163/20 Phase Not Applicable Recruiting 1 1000000 Martin Möckel 2020-09-24
Impact in the Medical Care Among the Rheumatic Diseases Patients in a Tertiary Hospital in Mexico During the COVID-19 Pandemic Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder, Rheumatoid arthritis Usual medical care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto Nacional de Ciencias Medicas y Nutricion Mexico 2020-07-01 2020-12-31 IRE-3467, NCT04557358 Phase Not Applicable Recruiting 1 6 Months 346 Irazú Contreras, Msc, Virginia Pascual Ramos, Principal Investigator, Virginia Pascual, MD 2020-09-24
EDSAB-HOME: Evaluating home antibody test kits for the detection of coronavirus (COVID-19) antibodies Coronavirus disease 19 infection T-SPOT Discovery SARS-CoV-2 test alone, blood sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Public Health England National Institute for Health Research (NIHR), Oxford Immunotec Ltd UK 2020-04-01 2021-06-01 CPMS 45951, IRAS 284980, EDSAB-HOME, ISRCTN56609224 Phase 2 Clinical Recruiting 8 14 Months 3000 Dr David Wyllie 2020-10-06
Evaluation of efficacy of Fixed Ayurvedic Regimen of Giloy Ki Ghan Vati,Tulsi Tablets,Kalmegh Tablets and Dabur Chyawanprash in COVID-19 Coronavirus disease 19 infection Variable regimens including Dabur chyawanprash , Giloy ki Ghanvati , Kalmegh Tablets , Tulsi tablets Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Dabur India Ltd India 2020-09-22 CTRI/2020/09/027914 Phase 2/Phase 3 Clinical Not yet recruiting 1 72 Dr Arun Gupta, Dr Narendra B Mundhe, Dr Sanjay Tamoli 2020-09-30
TURMERIC trial: Transcendental Meditation (TM) to reduce stress and improve immunity of health care providers during COVID-19 pandemic Acute stress disorder, Coronavirus disease 19 infection Transcendental Meditation (TM) alone, regular daily activities alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Medical Sciences India 2020-09-15 CTRI/2020/09/027910, TURMERIC trial Phase 2/Phase 3 Clinical Not yet recruiting 1 80 Dr Hemanga K Bhattacharjee, Rini Vohra 2020-09-23
A prospective/retrospective study to evaluate the safety and efficacy of ruxolitinib in patients with COVID-19 and severe systemic hyperinflammation Coronavirus disease 19 infection, Inflammatory disease ruxolitinib alone Jak1 tyrosine kinase inhibitor, Jak2 tyrosine kinase inhibitor Friedrich Schiller University of Jena Phase Not Applicable Status not specified 0 14 2020-10-06
Pulmonary Manifestations and Management of COVID-19 Pediatric Patients Admitted in a Tertiary Government Hospital Coronavirus disease 19 infection azithromycin alone, convalescent plasma alone, hydroxychloroquine alone, intravenous immunoglobulin alone, lopinavir + ritonavir alone, vitamin D3 alone, zinc sulfate alone HIV protease inhibitor Philippine General Hospital Philippines 2020-07-29 PHRR200915-002937 Phase Not Applicable Recruiting 1 Kevin Bautista, MD, FPPS, FPAPP, Maria Cristina H. Lozada, MD, DPPS, DPAPP, Wright H. Alborote, Wright H. Alborote, MD, DPPS 2020-09-24
Identification of Differences in Breath Components Detected With IMS in Patients Tested on SARS-CoV-2 (COVID-19) Coronavirus disease 19 infection Ion Mobility Spectrometry alone, ultrasound-based spirometer alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) B Braun Melsungen AG Germany 2020-09-30 2021-03-31 HC-N-H-2004, NCT04556318 Phase Not Applicable Recruiting 1 6 Months 100 Christoph Spinner, PD Dr., Study Manager 2020-10-01
RECOVIDS: Functional Recovery From Acute Respiratory Distress Syndrome (ARDS) Due to COVID-19: Influence of Socio-Economic Status Coronavirus disease 19 infection, Psychiatric disorder, Respiratory distress syndrome clinical examination alone, respiratory functional test alone, semi-directive interview alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire Dijon France 2020-09-18 2021-11-30 NCT04556513, QUENOT 2020, RECOVIDS Phase Not Applicable Recruiting 1 14 Months 500 Jean-Pierre QUENOT, Pierre-Louis DECLERCQ 2020-09-23
imPulse Una Full-spectrum, Over Clothing E-stethoscope Coronavirus disease 19 infection Philips Lumify Ultrasound System alone, imPulse Una e-stethoscope alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Johns Hopkins University US 2020-10-01 2020-12-31 00110011, NCT04556149 Phase Not Applicable Recruiting 1 3 Months 30 Ed Fuchs, MBA, Fuchs, MBA, Jumbe, PhD, Kelly Dooley, MD, PhD 2020-10-06
COVID-19 Ad Intervention Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of California Irvine The University of Hong Kong, University of California Los Angeles US 2020-09-29 2022-07-28 COVID-AD, NCT04555122 Phase Not Applicable Not yet recruiting 1 22 Months 52500 Arjuna Dugarte, Arjuna Ugarte 2020-09-24
A case-report study of neonatal early-onset infection with SARS-CoV-2 in a newborn presenting with encephalitic symptoms Coronavirus disease 19 infection, Encephalitis, Viral pneumonia caffeine alone, intravenous fluids alone, paracetamol alone Healthy volunteers accepted, Female Technische Universitat Dresden Phase Not Applicable Status not specified 0 1 2020-09-28
Mindfulness-based Crisis Intervention for COVID-19 Frontline Healthcare Workers During COVID-19 Coronavirus disease 19 infection Mindfulness based intervention alone Healthy volunteers accepted Instituto de Investigación Hospital Universitario La Paz La Paz University Hospital (Madrid) Spain 2020-03-10 2020-04-26 MIND-COVID-19, NCT04555005 Phase Not Applicable Completed 1 1 Month 1000 2020-09-24
CONFIN-AMP: Experience of Lock Down Related to the Covid-19 Epidemic and Its Impact on the Project of Parenthood Anxiety disorder, Coronavirus disease 19 infection, Depression Assisted Reproduction alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Regional Universitaire de Lille France 2020-10-31 2020-12-31 2020-A01810-39, 2020_65, CONFIN-AMP, NCT04556630 Phase Not Applicable Not yet recruiting 1 2 Months 360 Bérengère DUCROCQ, MD 2020-09-24
Determining the Physical Activity Level of Healthy Adults During Pandemic Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Pamukkale University Turkey 2020-04-11 2020-08-20 2020/8/318, NCT04555954 Phase Not Applicable Completed 1 4 Months 205 EMEL TAŞVURAN HORATA, PhD, Emel TAŞVURAN HORATA 2020-09-22
ASPIRE: Performance Evaluation of LumiraDx COVID-19 (SARS-CoV-2) Ag Test Coronavirus disease 19 infection LumiraDx SARS-CoV-2 Ag kit alone LumiraDx UK Ltd US 2020-06-26 2020-12-31 ASPIRE, NCT04557046, S-CLIN-PROT-00032 Phase Not Applicable Recruiting 7 6 Months 400 Andre Gvozden, Christopher Chappel, Daivd Craig, David Craig, Edward Zissman, Kimberley Henderson, Madhavi Ampajwala, Melanie Hoppers, Raechel Lapel, MPH, Robert Rosen 2020-09-24
MIND/COVID-19: Mental Health Impact and Needs Associated With COVID-19: a Comprehensive National Evaluation in Spain Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder, Suicide Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institut Municipal D'Investigació Mèdica (Imim) Fundacio Institut De Recerca De L'Hospital De La Santa Creu I Sant Pau, Fundacion Clinic per a la Recerca Biomédica, Generalitat de Cataluna, Hospital El Bierzo, Hospital General Universitario Gregorio Marañon, Hospital Torrecárdenas, Hospital Universitario 12 de Octubre, Hospital Universitario Araba(Spain), Hospital Universitario Donostia, Hospital Universitario Principe de Asturias, Hospital Vall D'Hebron, Hospital de Cruces, Hospital del Mar, Instituto de Salud Carlos III, Jordi Gol i Gurina Foundation, Parc Sanitari Sant Joan de Déu, Universitat Pompeu Fabra, University of Valencia Spain 2020-05-08 2021-05-31 2020/9203/I, NCT04556565 Phase Not Applicable Recruiting 18 12 Months 16000 Alma D. Martínez de Salazar, Ana González Pinto, Andrés Aragón Peña, Aurora Pérez Zapata, Consol Serra Pujadas, Cristina Rius Gibert, Eduard Vieta, Enric Aragonés Benaiges, Jordi Alonso, MD, Josep M. Haro Abad, José I. Emparanza Knörr, José Ignacio Pijoan Zubizarreta, José María Pelayo Terán, Juan de Dios Molina Martín, M. Isabel Del Cura González, Mara Parellada, Maria Teresa Puig Reixach, Meritxell Espuga Jordana, Mireia Campos Salanova, Nieves López Fresneña, Nieves Plana Farrás, Rafael M. Ortí Lucas, Víctor Pérez Solà 2020-09-23
Stress and Coping Among Health Workers During Covid Acute stress disorder, Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Malabar Cancer Centre India 2020-09-28 CTRI/2020/09/027908 Phase Not Applicable Not yet recruiting 1 600 Jisha Abraham 2020-09-24
Stress of Doctors in Covid era Acute stress disorder, Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Nizam's Institute of Medical Sciences India 2020-10-01 CTRI/2020/09/027907 Phase Not Applicable Not yet recruiting 1 300 Dr M Naveen Kumar, naveenjust@gmail.com 2020-09-23
Autologous whole blood injection as treatment for Covid-19 infection Coronavirus disease 19 infection Autologous whole blood injection alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) India 2020-10-02 CTRI/2020/09/027904 Phase 2 Clinical Not yet recruiting 1 60 Dr M Christopher 2020-09-23
Surgical Consent During the COVID-19 Pandemic Coronavirus disease 19 infection, Surgical procedure breast surgery alone, general surgery alone, vascular surgery alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Medway NHS Foundation Trust UK 2020-04-10 2020-08-14 2021.016N, NCT04556604 Phase Not Applicable Completed 1 4 Months 45 Oloruntobi Rotimi 2020-09-22
SHIFT-UC: A Study With GB-004 in Adult Subjects With Active Ulcerative Colitis (UC) Coronavirus disease 19 infection, Ulcerative colitis GB-004 alone HIF prolyl hydroxylase-2 inhibitor, Hypoxia inducible factor-1 stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gossamer Bio US 2020-09-30 2022-04-30 2020-002306-12, GB004-2101, NCT04556383, SHIFT-UC Phase 2 Clinical Recruiting 4 19 Months 195 Barrett Levesque, MD, Gossamer Bio, Inc, Principal Investigator 2020-10-05
Testing the efficacy and safety of a blood product COVID-19 Hyper-Immuneglobulin (Human) Solution in Participants with Active COVID-19 Coronavirus disease 19 infection anti-SARS-CoV-2 hyperimmune globulin therapy (intravenous, COVID-19), Intas alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Intas Pharmaceuticals Ltd India 2020-09-22 0279-20, CTRI/2020/09/027903 Phase 2 Clinical Not yet recruiting 2 60 Dr Naman Shah, Dr Rajesh Gosavi, Dr Vipul Thakkar, Mr Prashant Modi 2020-10-01
A Review on Ct-value of rRT-PCR among COVID-19 cases in Terengganu Coronavirus disease 19 infection Sultanah Nur Zahirah Hospital Malaysia 2020-10-01 2020-12-31 56400, NMRR-20-1976-56400 Phase Not Applicable Status not specified 1 3 Months 90 Dr Wan Norliyana binti Wan Mahmud 2020-09-24
Epidemiological Analysis Coronavirus disease 19 infection Malaysia 2020-09-28 2020-10-28 56437, NMRR-20-1981-56437 Phase Not Applicable Status not specified 1 1 Month 121 Dr Mohamad Afiq Amsyar Bin Hamedin 2020-09-23
A randomized, double-blind, placebo-controlled, multicenter, phase III clinical study to assess safety and efficacy of favipiravir in the early treatment outpatient setting for adult COVID-19 infections ith mild to moderate symptoms Coronavirus disease 19 infection favipiravir alone RNA polymerase inhibitor Appili Therapeutics Inc US Phase 3 Clinical Planned 1 826 2020-09-22
New Treatment for COVID-19 Using Ethanol Vapor Inhalation Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure asprin plus ethanol vapor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Mansoura University Egypt 2020-10-01 2022-06-01 20.08.79, NCT04554433 Phase 3 Clinical Not yet recruiting 1 20 Months 80 Ragab 2020-09-22
NOXCOVID-1: A Dose-Escalation and Dose-Expansion Study of NOX-66 in the Treatment of COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory insufficiency, Sepsis, Septic shock idronoxil (suppository, late-stage prostate cancer/soft tissue sarcoma/cancers/COVID-19-associated diseases), Noxopharm alone CASP8-FADD-like regulator inhibitor, Ecto NOX disulfide thiol exchanger 2 inhibitor, Sphingosine kinase inhibitor, Sphingosine-1-phosphate receptor-1 antagonist, Stimulator of interferon genes protein stimulator, Topoisomerase inhibitor, X-linked inhibitor of apoptosis protein inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Noxopharm Ltd Eastern Europe, Moldova, Republic of, Ukraine 2020-09-30 2021-06-30 NCT04555213, NOX66-007, NOXCOVID-1 Phase 1b Clinical Recruiting 2 9 Months 40 Gisela Mautner, MD, PhD 2020-10-12
Hemodynamic Impact on Critical Care Patients With Lung Damage Secondary to COVID-19 Coronavirus disease 19 infection, Lung injury, Respiratory distress syndrome EV1000 alone, HemoSphere alone, radial artery cannulation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Andalusian Network for Design and Translation of Advanced Therapies Edwards Lifesciences Corp Spain 2020-10-01 2021-04-01 FAB-HEM-2020-01, NCT04556864 Phase Not Applicable Not yet recruiting 5 6 Months 67 Francisco Cota Delgado, MD, Francisco Javier Maynar, MD, Javier Ripollés-Melchor, MD, Juan Victor Lorente, Juan Victor Lorente, MD, Manuel Ignacio Monge García, MD, Mario Marquez, MD 2020-09-22
A multicenter, multi-national observational study to evaluate the correlation between COVID-19 infection and stroke risk Coronavirus disease 19 infection, Stroke Geisinger Health System India, New Zealand, Lebanon, Brazil, Greece, US, Canada, Turkey, Iran, South America, Finland, Italy, Europe, North America, Asia Phase Not Applicable Status not specified 11 26175 2020-09-22
CaVaR-Co19: Cardiovascular Risk Stratification in COVID-19 Cardiovascular disease, Coronavirus disease 19 infection COVID-19 test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Oregon Health Sciences University US 2020-06-08 2021-12-31 CaVaR-Co19, NCT04555187, STUDY00021368 Phase Not Applicable No longer recruiting 1 18 Months 60000 Larisa G Tereshchenko, MD, PhD 2020-09-23
COVID-19 Disease Duration and GIT Manifestations. A New Disease Severity Classification. An Egyptian Experience Bacterial infection, Coronavirus disease 19 infection, Gastrointestinal disease Empiric antibiotic therapy alone, anticoagulant therapy alone, Variable regimens including hydroxychloroquine , vitamin c , zinc Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cairo University Egypt 2020-06-01 2020-07-15 1004, NCT04554979 Phase Not Applicable Completed 2 1 Month 199 Ahmed M Abdul Ghani, MD, Hoda M abdel-Hamid, MD, Mahmoud Wahba, MD, Mohamed Tharwat Hegazy, MD, Mona M Hegazy, MD, Omar Ashoush, MD, Rania M Lithy, MD 2020-09-23
Evaluation of primary preventive measures in populations at high risk for novel coronavirus pneumonia (COVID-19) sequelae osteonecrosis of the femoral head -- a prospective, randomized controlled trial Coronavirus disease 19 infection, Osteonecrosis, Viral pneumonia Jianpi Kanggu Granules alone, Xianling Gubao Capsule alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) The Third affiliated Hospital of Beijing Traditional Chinese Medicine University China 2020-08-01 2021-08-01 ChiCTR2000038343, ChiMCTR2000003941 Phase 0 Clinical Not yet recruiting 2 12 Months 120 Chen Weiheng, Xue Zhipeng 2020-10-13
A clinical trial of MP-0423 for the potential treatment of COVID-19 Coronavirus disease 19 infection MP-0423 alone COVID19 Spike glycoprotein inhibitor Molecular Partners AG 2021-06-30 Phase Not Applicable Planned 0 2020-09-24
A phase I trial of MAN-19 to treat complications caused by COVID-19 Coronavirus disease 19 infection MAN-19 alone Tek tyrosine kinase receptor stimulator Q BioMed Inc Phase 1 Clinical Planned 0 2020-09-21
COVIDIG: COVID-19 Hyper-Immunoglobulin Coronavirus disease 19 infection, Viral pneumonia GC-5131A alone Immunoglobulin agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) GC Pharma South Korea 2020-09-20 2021-08-31 COVIDIG, GC5131A-HIG_P0201, NCT04555148 Phase 2a Clinical Recruiting 1 11 Months 60 Kyoung Ran Peck, Kyoung Ran Peck, Dr. 2020-09-22
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