Last updated: Nov 18, 2020 - 02:00 GMT
| Ampligen in Chronic Fatigue Syndrome |
Chronic fatigue syndrome, Coronavirus disease 19 infection |
rintatolimod alone |
2,5-Oligoadenylate synthetase stimulator, Interferon type I receptor agonist, Ribonuclease stimulator, TLR-3 agonist |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
AIM ImmunoTech Inc |
|
US |
|
|
AMP 511, NCT00215813 |
Phase 3 Clinical |
Recruiting |
2 |
|
|
Ann Marie Coverly, Charles Lapp, MD, Charles W. Lapp, M.D., Daniel Peterson, M.D., Daniel Peterson, MD, Diane Young |
2020-10-27 |
| Baseline Vitamin D Deficiency and COVID-19 Disease Severity |
Coronavirus disease 19 infection, Vitamin D deficiency |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Parkview Medical Center |
|
US |
2020-10-27 |
2022-04-14 |
NCT04628000, PIRB78 |
Phase Not Applicable |
Recruiting |
0 |
17 Months |
50 |
Doug Duffee, Doug Duffee, MD, Stephaine Lucas, MD, Stephanie Lucas, MD |
2020-11-17 |
| Efficacy of Yoga Based Self-Management Program for Chronic Pain |
Coronavirus disease 19 infection, Pain |
Yoga based self-management alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Aarogyam UK |
|
UK |
2020-09-17 |
2020-11-09 |
AU0211, NCT04628130 |
Phase Not Applicable |
Completed |
0 |
1 Month |
42 |
Deepa Modi, Neha Sharma, Sunita Poddar, Vishwesh Kulkarni |
2020-11-17 |
| A phase I/Ii clinical trial of PDS-0203 for the potential prevention of COVID-19 infection |
Coronavirus disease 19 infection |
PDS-0203 alone |
Coronavirus spike glycoprotein inhibitor |
|
PDS Biotechnology Corp |
|
|
2021-06-30 |
|
|
Phase 1/Phase 2 Clinical |
Planned |
0 |
|
|
|
2020-11-17 |
| Covid19 Antibody prevalence and sustainability. A retrospective, longitudinal, mono-centered, observational study in Covid-19 PCR positive hospital workers |
Coronavirus disease 19 infection |
|
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Ernst von Bergmann Clinic |
|
Germany |
2020-11-20 |
|
DRKS00023561, S 30(bB)/2020 |
Phase Not Applicable |
Recruiting |
0 |
|
207 |
Maria Biersack |
2020-11-17 |
| A case-control study to assess safety and efficacy of lenzilumab in the treatment of patients with severe COVID-19 and acute respiratory distress syndrome (ARDS) |
Coronavirus disease 19 infection, Respiratory distress syndrome |
lenzilumab alone |
GM-CSF ligand inhibitor, Immunoglobulin G1 modulator, Immunoglobulin kappa modulator |
|
Humanigen Inc |
|
US |
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
39 |
|
2020-11-17 |
| A phase II clinical study to assess STI-2099 either as a stand-alone nasal application or as a combination nasal and intravenous administration in both mild and moderate COVID-19 patients |
Coronavirus disease 19 infection |
STI-2099 alone |
|
|
Sorrento Therapeutics Inc |
|
|
|
|
|
Phase 2 Clinical |
Planned |
0 |
|
|
|
2020-11-17 |
| A phase I safety and pharmacokinetic study of STI-2099 in healthy subjects and outpatients with mild COVID-19 disease with or without a simultaneous intravenous injection of COVI-AMG |
Coronavirus disease 19 infection |
STI-2099 alone, COVI-AMG plus STI-2099 |
COVID19 Spike glycoprotein inhibitor |
Healthy volunteers accepted |
Sorrento Therapeutics Inc |
|
|
|
|
|
Phase 1 Clinical |
Planned |
0 |
|
|
|
2020-11-17 |
| A Phase II Clinical Trial of MW-33 Injection in Patients With COVID-19 |
Coronavirus disease 19 infection |
MW-33 alone |
COVID19 Spike glycoprotein inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Mabwell (Shanghai) Bioscience Co Ltd |
|
|
2020-11-30 |
2021-09-30 |
MW33-2020-CP201, NCT04627584 |
Phase 2 Clinical |
Not yet recruiting |
0 |
10 Months |
150 |
Bei ZHAO, Master, Song LU, Master |
2020-11-17 |
| Echo-COVID: Cardiac Performance in Mechanically Ventilated COVID-19 Patients |
Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia |
Mindray M9 (Bio-Medical Electronics Co) alone, Philips CX 50 (Philips Healthcare) alone, Vivid i echocardiography system (GE Medical Systems) alone, echocardiography alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Pontificia Universidad Catolica De Chile |
Clinica Alemana de Santiago, Hospital Barros Luco Trudeau, University of Chile |
Chile |
2020-04-01 |
2020-08-01 |
200422002, Echo-COVID, NCT04628195 |
Phase Not Applicable |
Completed |
1 |
4 Months |
100 |
Emilio Valenzuela, M.D |
2020-11-17 |
| Expanded Evaluation of the Survivorship Wellness Group Program in the Context of COVID-19 and Telehealth |
Anxiety disorder, Coronavirus disease 19 infection, Depression |
Survivorship Wellness Group Program alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of California San Francisco |
|
US |
2020-08-31 |
2023-12-31 |
20805, NCI-2020-08530, NCT04630015 |
Phase Not Applicable |
Recruiting |
1 |
40 Months |
250 |
Alison Chang, Diane Shumay, PhD, Margaret Chesney, MD, Margaret Chesney, PhD, cancertrials@ucsf.edu |
2020-11-17 |
| A retrospective cohort study to examine outcomes among patients who were treated anakinra or tocilizumab for COVID-19 -related cytokine storm |
Coronavirus disease 19 infection |
anakinra alone, tocilizumab alone |
Type I IL-1 receptor antagonist |
|
University of California Los Angeles |
|
US |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
93 |
|
2020-11-17 |
| Face Masks to Reduce COVID-19 in Bangladesh |
Coronavirus disease 19 infection |
Face mask alone, face mask awareness alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Yale University |
Innovation for poverty action, Stanford University |
Bangladesh |
2020-11-15 |
2021-02-28 |
2000028482, NCT04630054 |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
450000 |
Jason Abaluck, PhD, Md. Alamgir Kabir, BA, Mohammad Ashraful Haque, BA, Stephen P Luby, MD |
2020-11-17 |
| Effect of Covid-19 on Outcomes of Pregnancy |
Coronavirus disease 19 infection |
PCR test alone |
|
Healthy volunteers accepted, Female, Young Adults (18-44 yrs) |
Assiut University |
|
Egypt |
2020-09-01 |
2021-12-01 |
12789, NCT04629001 |
Phase Not Applicable |
No longer recruiting |
0 |
15 Months |
1000 |
Armia Michael |
2020-11-17 |
| A real-world study to evaluate T-Detect COVID for past infection |
Coronavirus disease 19 infection |
T-Detect COVID alone |
|
|
Adaptive Biotechnologies Corp |
|
Italy |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
|
|
2020-11-17 |
| COVID-19 Infection Rate in the Construction- and Cleaning Industry |
Coronavirus disease 19 infection |
Spirometry alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Arbeitsmedizinischer Dienst der BG BAU GmbH |
Berufsgenossenschaft der Bauwirtschaft |
Germany |
2020-11-22 |
|
BO/40/2020, DRKS00023558 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
3000 |
Thomas Solbach |
2020-11-17 |
| A retrospective case-control study to evaluate the impact of tocilizumab on mortality and/or invasive mechanical ventilation requirement in a cohort COVID-19 patients |
Coronavirus disease 19 infection |
Invasive mechanical ventilation alone, tocilizumab alone |
|
|
Hôpital Nord Franche-Comté |
|
France |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
206 |
|
2020-11-17 |
| Verification of stress relief by introducing online visits to the restrictions on visits of COVID-19 |
Acute stress disorder, Coronavirus disease 19 infection |
online visit alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Jinseikai Kohnan Hospital |
|
Japan |
2020-11-16 |
|
UMIN000042384 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Hiroshi Yamamoto |
2020-11-17 |
| Maternal Attachment and Depression Anxiety Score Evaluation in (SARS-CoV-2) Positive Pregnant Women |
Anxiety disorder, Coronavirus disease 19 infection, Depression |
|
|
Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Istanbul Bakirkoy Maternity and Children Diseases Hospital |
|
Turkey |
2020-08-01 |
2020-11-20 |
MATERNALATTACHMENTCOVID, NCT04629638 |
Phase Not Applicable |
No longer recruiting |
1 |
3 Months |
500 |
Pınar Yalcin bahat |
2020-11-17 |
| RECOVER: Regenerative Medicine for COVID-19 and Flu-Elicited ARDS Using Longeveron Mesenchymal Stem Cells (LMSCs) |
Adult respiratory distress syndrome, Coronavirus disease 19 infection, Influenza virus infection |
allogeneic human mesenchymal stem cells (aging frailty/Alzheimer's disease/metabolic syndrome/hypoplastic left heart syndrome), Longeveron alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Longeveron LLC |
|
US |
2020-07-24 |
2025-07-31 |
00-006, NCT04629105, RECOVER |
Phase 1 Clinical |
Recruiting |
3 |
60 Months |
70 |
Andrew Quartin, MD, Anthony Oliva, PhD, Carl Shanholtz, MD, Freshta Akbari, MS, Gisel Urdaneta, MD, John P Galliard, MD, Kevin N Ramdas, MD, MPH, Kristopher Deatrick, MD, Mary- Clare Day, RN, BSN, CCRC, Roland Schein, MD, Sunjay Kaushal, MD, PhD |
2020-11-17 |
| CODED: Risk Stratification of COVID-19 Patients Discharged From the Emergency Department |
Coronavirus disease 19 infection |
chest radiography alone, lung ultrasonosgraphy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Azienda Ospedaliera Citta della Salute e della Scienza di Torino |
University of Turin |
Italy |
2020-11-01 |
2021-07-31 |
CODED, COVID-ED-INTRISK, NCT04629183 |
Phase Not Applicable |
Recruiting |
5 |
9 Months |
400 |
Emanuele E Pivetta, MD, PhD, Enrico Lupia, MD, PhD, Franco Aprà, MD, Fulvio Morello, MD, PhD, Giuseppe Lauria, MD, Peiman Nazerian, MD, Stefano Podio, MD |
2020-11-17 |
| LAVA: The LAVA (Lateral Flow Antigen Validation and Applicability) Study for COVID-19 |
Coronavirus disease 19 infection |
Innova Lateral Flow Device alone, RT-PCR alone |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) |
Alder Hey Children's NHS Foundation Trust |
|
UK |
2020-11-05 |
2020-11-19 |
290989, LAVA, NCT04629157 |
Phase Not Applicable |
Recruiting |
2 |
|
400 |
Beatriz Larru, MD, Christopher Kelly, Laura Rad, Lucy Cooper, Rachel Harwood, MB BS, Richard Kirk |
2020-11-17 |
| A phase II trial of BNT-162b2 for the treatment of COVID-19 |
Coronavirus disease 19 infection |
BNT-162b2 alone |
COVID19 Spike glycoprotein modulator |
|
Shanghai Fosun Pharmaceutical (Group) Co Ltd |
|
China |
|
|
|
Phase 2 Clinical |
Not yet recruiting |
1 |
|
|
|
2020-11-17 |
| Double-Blind, Randomized, Placebo-Controlled, Adaptive-Design, Multicenter, Phase III Study to Evaluate the Efficacy and Safety of Fostamatinib in COVID-19 Subjects |
Coronavirus disease 19 infection |
fostamatinib disodium alone, standard of care alone |
Syk tyrosine kinase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Rigel Pharmaceuticals Inc |
|
|
2020-12-31 |
2021-08-31 |
C-935788-061, NCT04629703 |
Phase 3 Clinical |
Not yet recruiting |
0 |
8 Months |
308 |
|
2020-11-17 |
| EST-OBS-OZO-BIOPLA-SARS-COV 2: Observational study benefits rectal ozone therapy and BIOPLA as complementary therapy in convalescent patients SARS-COV-2 |
Coronavirus disease 19 infection |
BIOPLA alone, rectal ozone therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Center for Scientific Research, Cuba |
BioCubaFarma |
Cuba |
2020-06-08 |
2020-08-15 |
EST-OBS-OZO-BIOPLA-SARS-COV 2, RPCEC00000342 |
Phase Not Applicable |
No longer recruiting |
1 |
2 Months |
40 |
Mario Slim War, Zullyt Zamora Rodriguez |
2020-11-17 |
| A clinical trial to evaluate the safety and pharmacokinetics of COVI-AMG in healthy subjects |
Coronavirus disease 19 infection |
COVI-AMG alone |
COVID19 Spike glycoprotein inhibitor |
Healthy volunteers accepted |
Sorrento Therapeutics Inc |
|
US |
|
|
|
Phase Not Applicable |
Not yet recruiting |
1 |
|
|
|
2020-11-17 |
| A retrospective study of zinc sulfate in combination with a zinc ionophore may improve outcomes in hospialized COVID-19 patients |
Coronavirus disease 19 infection |
Variable regimens including azithromycin , hydroxychloroquine , zinc sulphate |
|
|
New York University School of Medicine, US |
|
US |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
932 |
|
2020-11-17 |
| Tracheobronchitis in Respiratory Involvement on the Lung SPECT/CT Images of COVID-19 Patients |
Coronavirus disease 19 infection, Dyspnea, Tracheobronchitis |
perfusion lung scintigraphy alone, ventilation alone |
|
|
Central Hospital, Nancy, France |
|
France |
2020-03-11 |
2020-07-23 |
2020PI154, NCT04629222 |
Phase Not Applicable |
Completed |
1 |
4 Months |
10 |
Pierre Yves MARIE, PhD |
2020-11-17 |
| Clinical trial to evaluate superiority of anti-SARS-CoV-2 convalescent plasma versus standard-of-care in hospitalized patients with mild COVID-19 |
Coronavirus disease 19 infection |
Fresh frozen plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Hannover Medical School |
German Federal Ministry of Health |
Germany |
2020-10-19 |
|
2020-001936-86, COMET |
Phase 2 Clinical |
Recruiting |
1 |
|
340 |
Institute of Transfusion Medicine |
2020-11-17 |
| NOTICE: A retrospective chart review study,to collect real-world data on the use of Inomax (nitric oxide) gas, for inhalation therapy in patients with respiratory complications associated with the novel coronavirus SARS-CoV-2 (COVID-19) |
Coronavirus disease 19 infection, Hypoxia, Respiratory disease |
nitric oxide (inhaled), Ikaria alone |
Hemoglobin modulator |
|
Mallinckrodt plc |
Pharmerit International |
|
|
|
NOTICE |
Phase 4 Clinical |
Status not specified |
0 |
|
|
|
2020-11-16 |
| IPCO: Prospective, open-label, randomized, controlled, phase IIb clinical study in parallel groups for the assessment of efficacy and safety of immune therapy with COVID-19 convalescent plasma plus standard treatment versus standard treatment alone of subjects with severe COVID-19 |
Coronavirus disease 19 infection |
convalescent plasma alone, standard treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universitatsklinikum Erlangen |
|
Germany |
2020-06-12 |
|
2020-002122-82, IPCO, UKER-COV2-01 |
Phase 2b Clinical |
Recruiting |
1 |
|
58 |
Transfusionsmedizinische Abteilung |
2020-11-16 |
| A retrospective observational cohort study of clinical characteristics and predictors of survival in adults with coronavirus disease 2019 receiving tocilizumab |
Coronavirus disease 19 infection |
tocilizumab alone |
|
|
Henry Ford Health System |
|
US |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
81 |
|
2020-11-16 |
| Effect of COVID-19 on exercise pattern, diet pattern and weight change in athletes |
Coronavirus disease 19 infection |
questionnaire alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs) |
Welcomgroup Graduate School of Hotel Administration |
|
India |
2020-11-21 |
|
CTRI/2020/11/029124 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
336 |
Rachana, Swathi Acharya |
2020-11-16 |
| A prospective study on the interobserver variability of COVID-19 Reporting and Data System (CO-RADS) among radiologists in the Philippine General Hospital |
Coronavirus disease 19 infection |
CO-RADS alone |
|
|
Philippine General Hospital, University of the Philippines |
|
Philippines |
2020-08-01 |
2020-11-10 |
PHRR201116-003153 |
Phase Not Applicable |
Completed |
1 |
3 Months |
|
Gerard Eastdon Ochoco |
2020-11-17 |
| The Largest Cluster of Covid-19 in Jerantut |
Coronavirus disease 19 infection |
|
|
|
Jabatan Kesihatan Negeri Pahang |
|
Malaysia |
2020-11-05 |
2020-12-01 |
57119, NMRR-20-2448-57119 |
Phase Not Applicable |
Status not specified |
1 |
|
|
Dr ATIRAH BINTI MOHD AZIZUL |
2020-11-17 |
| A clinical trial of AT-301 (nasal spray, COVID-19), Atossa Therapeutics for the treatment of covid-9 infection |
Coronavirus disease 19 infection |
AT-301 (nasal spray, COVID-19), Atossa Therapeutics alone |
COVID19 Spike glycoprotein inhibitor |
|
Atossa Therapeutics Inc |
|
|
|
|
|
Phase 2 Clinical |
Planned |
0 |
|
|
|
2020-11-16 |
| A study to evaluate the impact of COVID-19 on patients with cystic fibrosis |
Coronavirus disease 19 infection, Cystic fibrosis |
|
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Cystic Fibrosis Foundation |
|
Spain, Switzerland, Russian Federation, Canada, Germany, France, Chile, Ireland, Sweden, Australia, South Africa, US, Belgium, New Zealand, Italy, UK, Brazil, Argentina, Netherlands |
|
|
|
Phase Not Applicable |
Status not specified |
19 |
|
181 |
|
2020-11-16 |
| HCW-Wristband: Colour-Coded Wristband to Monitor COVID-19 Exposure Status for Healthcare Workers On Early Return to Work After a COVID-19 close contact: A Pilot Study |
Coronavirus disease 19 infection |
coloured wristband alone |
|
Healthy volunteers accepted |
HOSPITAL QUEEN ELIZABETH II |
|
Malaysia |
2020-11-30 |
2021-06-30 |
56966, HCW-Wristband, NMRR-20-2443-56966 |
Phase Not Applicable |
Status not specified |
1 |
7 Months |
|
Dr Teoh Eu Vin, Dr. Liew Houng Bang |
2020-11-16 |
| Clinical characteristics and outcomes of ventilated COVID-19 patients in Sungai Buloh Hospital |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Sungai Buloh |
|
Malaysia |
2020-12-01 |
2021-02-27 |
54853, NMRR-20-2441-54853 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
50 |
Dr Nor Haliza Binti Zainol Abidin |
2020-11-17 |
| To study the Influence of Food habits, Physical activity and knowledge of pregnant mothers on the problems faced in pregnancy, type of delivery and Birth weight of newborn during COVID-19 times |
Coronavirus disease 19 infection, Pregnancy disorder |
telephonic counselling alone |
|
Female, Young Adults (18-44 yrs) |
Welcomgroup Graduate School of Hotel Administration |
|
India |
2020-11-20 |
|
CTRI/2020/11/029070 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
300 |
Anuhitha Paruchuri, Dr Meenakshi Garg, Rasmiya |
2020-11-17 |
| Study of heart injury by laboratory investigation in corona positive patients |
Coronavirus disease 19 infection, Heart injury |
|
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Sardar Vallabh Bhai Patel Hospital |
|
India |
2020-11-17 |
|
CTRI/2020/11/029068 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
200 |
Dr Vijaysinh Parmar |
2020-11-17 |
| LungCOVID: One year follow-ups of Chilean patients with COVID-19 |
Coronavirus disease 19 infection, Lung injury, Viral pneumonia |
blood test alone, chest scan alone, lung function test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universidad de Concepcion |
Agencia Nacional de Investigacion y Desarrollo, Chilean government |
Chile |
2020-09-11 |
2021-07-30 |
COVID1005, ISRCTN16865246, LungCOVID |
Phase Not Applicable |
Recruiting |
0 |
10 Months |
250 |
Dr Daniel Enos, Dr Gonzalo Labarca, Dr Jaime Lastra, Prof Nova-Lamperti |
2020-11-17 |
| RECAP: Assessing patients' risk of COVID-19 severe infection: developing a risk prediction score |
Coronavirus disease 19 infection |
Covid-19 templates in EMIS and SystmOne alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Imperial College London |
Economic and Social Research Council, NIHR Imperial Biomedical Research Centre, NIHR Oxford Biomedical Research Center |
UK |
2020-05-15 |
2021-04-01 |
IRAS 283024, CPMS 45890, ISRCTN13953727, RECAP |
Phase Not Applicable |
Recruiting |
0 |
10 Months |
2870 |
Dr BelenEspinosaGonzalez |
2020-11-17 |
| RECOVERY: A clinical trial of Aspirin for the treatment of blood clots in people with COVID-19 |
Coronavirus disease 19 infection |
aspirin alone, standard of care alone |
|
|
Nuffield Department of Population Health |
|
UK |
|
|
RECOVERY |
Phase Not Applicable |
Status not specified |
1 |
|
2000 |
Martin Landray, Peter Horby |
2020-11-16 |
| SOVEREIGN 01A: Phase I, randomized, double-blind and adaptive study to evaluate the safety, reactogenicity and explore the immunogenicity of different formulations of the Prophylactic Vaccine Candidates against SARS-CoV-2, FINLAY-FR-1 and FINLAY-FR-1A (COVID-19) |
Coronavirus disease 19 infection |
FINLAY-FR-1 alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Finlay Institute |
|
Cuba |
2020-10-19 |
2021-01-31 |
IFV / COR / 05, RPCEC00000338, SOVEREIGN 01A |
Phase 1 Clinical |
Recruiting |
1 |
3 Months |
60 |
Beatriz Moreno Walls, Meiby Rodriguez Gonzalez, Sonia Perez Rodriguez |
2020-11-16 |
| An accelerated design, combined, prospective ascending single-dose and two-dose, randomized, placebo-controlled, blinded, first-in-human adaptive study in healthy adults and patients with COVID-19 infection, to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of therapeutic antibody AOD01 |
Coronavirus disease 19 infection |
AOD01 alone |
|
Healthy volunteers accepted |
DSO National Laboratories |
|
Singapore |
|
|
AOD01-01 |
Phase 1/Phase 2 Clinical |
Status not specified |
1 |
|
|
Dr David Lye Chian Boon |
2020-11-16 |
| The efficacy and safety of systemic anticoagulation in novel coronavirus pneumonia (COVID-19): A medical records based retrospective cohort study |
Coronavirus disease 19 infection, Viral pneumonia |
systemic anticoagulation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tongji Hospital, Huazhong University of Science and Technology |
|
China |
2020-09-01 |
2022-08-31 |
ChiCTR2000039855 |
Phase Not Applicable |
Not yet recruiting |
1 |
24 Months |
750 |
Bian Yi |
2020-11-17 |
| A Descriptive Study on the Knowledge, Perceptions, Preferences and Challenges of OBGYNE Surgeons in Using Personal Protective Equipment for COVID-19 Precaution in the Operating Room |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted |
Philippine General Hospital |
|
Philippines |
2020-08-24 |
2020-09-05 |
PHRR201021-003052 |
Phase Not Applicable |
Completed |
1 |
|
|
Judith Faye M. Montero |
2020-11-15 |
| Correlation of CT severity scoring with clinical classification of disease in COVID-19 positive patients |
Coronavirus disease 19 infection |
|
|
|
University of the Philippines |
|
Philippines |
2020-05-01 |
2020-08-12 |
PHRR201021-003070 |
Phase Not Applicable |
Completed |
1 |
3 Months |
|
Clare Toledo |
2020-11-15 |
| MEMORY-COVID: Manganese-Enhanced Magnetic Resonance Imaging of Myocardial injury in COVID-19 |
Coronavirus disease 19 infection, Heart injury, Myocardial disease, Myocarditis, Systolic dysfunction |
computed tomography coronary angiography alone, electrocardiography alone, magnetic resonance imaging alone, gadolinium plus manganese |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Edinburgh |
|
UK |
2020-06-10 |
2022-06-10 |
20/NW/0249, MEMORY-COVID, NCT04625075 |
Phase Not Applicable |
Recruiting |
1 |
24 Months |
40 |
Shruti Joshi, MBBS, Trisha Singh, BM, Trisha Singh, BM, BMedSci |
2020-11-17 |
| PPEDiC: A study of parents views and motivations on presenting to their local pediatric emergency department during the coronavirus pandemic (COVID-19) |
Coronavirus disease 19 infection |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) |
University Hospital Lewisham |
|
UK |
2020-05-04 |
2020-12-31 |
IRAS 287536, ISRCTN12833010, PPEDiC |
Phase Not Applicable |
Not yet recruiting |
3 |
7 Months |
220 |
Dr Nyirenda, Dr Tina Sajjanhaar |
2020-11-14 |
| The effect of balloon-blowing on dyspnea and oxygenation in non-critical adult covid-19 patients |
Coronavirus disease 19 infection, Dyspnea |
balloon blowing alone, necessary medication alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Qazvin University Of Medical Sciences |
|
Iran |
2020-07-22 |
2020-10-30 |
IR.QUMS.REC.1399.043, IRCT20201012049010N1 |
Phase Not Applicable |
Completed |
1 |
3 Months |
90 |
Mohammad Bargahi, Mohammadali emamjomeh, Seyed Saeed Farzam |
2020-11-17 |
| OZO-EST-OBS: Prevalence of positive evolutive PCR in patients with COVID 19 treated with rectal ozone therapy: observational study prospective cohort |
Coronavirus disease 19 infection |
Ozone therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Center for Scientific Research, Cuba |
|
Cuba |
2020-08-15 |
2020-10-25 |
OZO-EST-OBS, OZO-EST-OBS-01, RPCEC00000341 |
Phase Not Applicable |
Completed |
1 |
2 Months |
200 |
Zullyt Zamora Rodriguez |
2020-11-17 |
| An Investigation of the impact of Faramir on the clinical symptoms in patients with COVID-19 |
Coronavirus disease 19 infection |
faramir containing Salvia officinalis extract (Meem Pharmaceutical Factory) alone, standard treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Shaheed Beheshti Medical University |
|
Iran |
2020-11-21 |
|
IR.SBMU.MSP.REC.1399.396, IRCT20170315033086N7 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
128 |
Minoosh Shabani, Saeed Karima, Somayeh Mahmoodi Baram |
2020-11-14 |
| ACCURATE-BL-COVID-19: COVID-19 in Baselland: Validation of Simple and Accurate Tests for COVID-19 Detection, Monitoring and Tracing |
Coronavirus disease 19 infection |
LAMP assay alone, NGS diagnostic assay alone, POCT antigen tests alone, crude RNA extraction alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Basel |
ETH Zurich, Kanton Basel- Landschaft |
Switzerland |
2020-12-31 |
2021-03-31 |
2020-01112, CH20SAVIC2, ACCURATE-BL-COVID-19, NCT04625257 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
3000 |
Miodrag Savic, Dr. med. Dr. med. dent. |
2020-11-17 |
| SOBERANA 02: Phase I study, open, sequential and adaptive for evaluating the safety, reactogenicity and explore the immunogenicity of the prophylactic Vaccine Candidate FINLAY-FR-2 anti SARS-CoV-2 (COVID-19) |
Coronavirus disease 19 infection |
FINLAY-FR-2 alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Finlay Institute |
|
Cuba |
2020-11-02 |
2021-06-01 |
IFV/COR/06, RPCEC00000340, SOBERANA 02 |
Phase 1 Clinical |
Not yet recruiting |
1 |
7 Months |
40 |
Beatriz, Maria Toledo Romani, Meiby Rodriguez Gonzalez |
2020-11-16 |
| MSC-COVID19: Efficacy of Infusions of MSC From Wharton Jelly in the SARS-Cov-2 (COVID-19) Related Acute Respiratory Distress Syndrome |
Coronavirus disease 19 infection, Multiple organ failure, Respiratory distress syndrome |
Wharton's jelly mesenchymal stem cells alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Central Hospital, Nancy, France |
|
France |
2020-11-06 |
2022-08-06 |
2020-002772-12, MSC-COVID19, NCT04625738 |
Phase 2a Clinical |
Not yet recruiting |
1 |
21 Months |
30 |
Bruno LEVY, MD, PhD, Cecile POCHON, MD, POCHON Cecile, Sebastien GIBOT, MD, PhD, Sébastien GIBOT, MD, PhD |
2020-11-13 |
| PROVENT: Phase III, Double-blind, Placebo-controlled Study of AZD-7442 for Pre-exposure Prophylaxis of COVID-19 in Adult |
Coronavirus disease 19 infection |
AZD-7442 alone |
COVID19 Spike glycoprotein inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
AstraZeneca plc |
Biomedical Advanced Research and Development Authority (BARDA), IQVIA Holdings Inc |
US, UK |
2020-11-17 |
2021-12-14 |
D8850C00002, NCT04625725, PROVENT |
Phase 3 Clinical |
Not yet recruiting |
2 |
12 Months |
5000 |
AstraZeneca Clinical Study Information Center, Myron Levin, MD |
2020-11-13 |
| DMMETCOV19: Metformin Glycinate in Patients With MS or DM2, Hospitalized With COVID-19 and SARS Secondary to SARS-CoV-2 |
Coronavirus disease 19 infection, Metabolic syndrome X, Non-insulin dependent diabetes |
metformin glycinate (diabetes/acute respiratory distress syndrome/COVID-19), Laboratorios Silanes alone, standard treatment alone |
AMP activated protein kinase stimulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Laboratorios Silanes SA De CV |
|
Mexico |
2020-11-30 |
2021-03-31 |
DMMETCOV19, NCT04626089, SIL-30000-II(1) |
Phase 3b Clinical |
Not yet recruiting |
1 |
4 Months |
20 |
Daniel Juarez, BPC, Fausto González-Villagrán, MD, Jorge Gonzalez-Canudas, MD, Nayeli Goreti, Yulia Romero-Antonio, B.S. |
2020-11-13 |
| DMMETCOV19-2: Metformin Glycinate, Treatment of Patients With COVID-19 and Severe Acute Respiratory Syndrome Secondary to SARS-CoV-2 |
Coronavirus disease 19 infection |
metformin glycinate (diabetes), Laboratorios Silanes alone, standard treatment alone |
AMP activated protein kinase stimulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Laboratorios Silanes SA De CV |
|
Mexico |
2020-07-14 |
2021-03-31 |
DMMETCOV19-2, NCT04625985, SIL-30000-II-20(2) |
Phase 3b Clinical |
Recruiting |
1 |
8 Months |
20 |
Janet S Aguirre, MD, Janet Silvia M Aguirre, MD, Jorge Gonzalez-Canudas, MD, Paulina Trapaga, MD, Yulia Romero-Antonio, B.S. |
2020-11-13 |
| COVecu: Behavior and Experience of Communities Healthcare Professionals Facing the SARS CoV-2 (COVID-19) Epidemic |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assistance Publique Hopitaux de Paris |
|
France |
2020-09-17 |
2021-01-31 |
AP-HP 200512, COVecu, NCT04625296 |
Phase Not Applicable |
Recruiting |
1 |
4 Months |
75 |
Flora DEVOS, Nurse MSC PhD, Flora DEVOS, nurse, Flora DEVOS, nurse Msc PhD, Marie BENHAMMANI |
2020-11-13 |
| The Potential of Oral Camostat in Early COVID-19 Disease in an Ambulatory Setting to Reduce Viral Load and Disease Burden |
Coronavirus disease 19 infection |
camostat mesylate alone, standard of care alone |
Serine protease inhibitor, Transmembrane serine protease 2 inhibitor, Trypsin inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universitair Ziekenhuis Gent |
|
Belgium |
2020-11-04 |
2023-01-01 |
2020-003475-18, NCT04625114 |
Phase 2 Clinical |
Recruiting |
1 |
25 Months |
150 |
Linos Vandekerckhove, Marie-Angélique De Scheerder |
2020-11-17 |
| SARCODO: Coagulopathy and Vasculopathy Assessment as a Predictor of the Severity of SARS-CoV-2/COVID-19 Infection |
Blood clotting disorder, Coronavirus disease 19 infection, Lung disease, Respiratory distress syndrome, Vascular disease |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assistance Publique Hopitaux de Paris |
Agence nationale de la recherche (ANR) |
France |
2020-06-08 |
2020-12-31 |
2020-A01048-31, APHP200521, NCT04624997, SARCODO |
Phase Not Applicable |
Recruiting |
2 |
6 Months |
1000 |
David M Smadja, David Smadja, Michaela FONTENAY, Natacha Nohilé |
2020-11-13 |
| NO-mediated Vascular Function in Covid-19 Patient |
Coronavirus disease 19 infection, Viral pneumonia |
ultrasound system (General Electric Medical Systems) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Istituti Clinici Scientifici Maugeri Spa Sb |
Universita di Verona |
Italy |
2020-05-30 |
2020-12-31 |
ICS MAUGERI 2437 CE, NCT04625036 |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
30 |
Mara Paneroni, PT, Paola Baiardi, Math |
2020-11-13 |
| A case-report study of a COVID-19 patient presented with psychotic disorder |
Coronavirus disease 19 infection, Delirium, Respiratory disorder, Viral pneumonia |
corticoid bolus alone, hydroxychloroquine alone, lopinavir alone, risperidone alone, ritonavir alone, tocilizumab alone |
5-HT 2 receptor antagonist, Cytochrome P450 3A4 inhibitor, Dopamine D2 receptor antagonist, HIV protease inhibitor, HIV-1 protease inhibitor |
Male |
Universidad De Salamanca |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
1 |
|
2020-11-13 |
| CHLORO-VID: Hydroxychloroquine for the Treatment of SARS-CoV2 (COVID 19): Pharmacokinetic Study |
Coronavirus disease 19 infection, Viral pneumonia |
hydroxychloroquine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire de Toulouse |
|
France |
2021-01-31 |
2021-05-31 |
2020-A01094-35, CHLORO-VID, NCT04625218, RC31/20/0155 |
Phase Not Applicable |
Not yet recruiting |
1 |
4 Months |
40 |
Stéphanie RUIZ, PH, Stéphanie RUIZ, ph |
2020-11-17 |
| UNITY Global: International Registry of Healthcare Workers Exposed to COVID-19 Patients |
Coronavirus disease 19 infection |
SARS-CoV-2 antibody serology testing alone, pharmaco-epidemiological inferential analysis alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Certara |
Bill & Melinda Gates Foundation, COVID -19 Therapeutics Accelerator, PAREXEL International |
Senegal, Nigeria, Zimbabwe, Uganda, Zambia, Kenya, South Africa, Pakistan |
2020-08-13 |
2021-10-31 |
CER-HCW-001, NCT04626076, UNITY Global |
Phase Not Applicable |
Recruiting |
8 |
14 Months |
10000 |
Craig Rayner, PharmD, Marta Martinez, PharmD, Roman Casciano, Masters, Zainab Samad, Dr. |
2020-11-17 |
| Burnout and resilience among internal medicine physicians in-training in a tertiary government hospital in Manila, Philippines during the COVID-19 pandemic: An exploratory mixed method study |
Acute stress disorder, Coronavirus disease 19 infection |
|
|
|
Philippine General Hospital |
|
Philippines |
2020-04-15 |
2020-07-30 |
PHRR201103-003115 |
Phase not specified |
Completed |
3 |
3 Months |
|
Jhaki A. Mendoza, Maria Rosario M. Bayan, Marvin E. Marquez, Patricia Gregoria V. Mina-Cuano, Paula Isabel G Franco, Paula Isabel Gimena Franco |
2020-11-13 |
| Study of Recombinant Protein Vaccine with Adjuvant against COVID-19 in Adults 18 Years of Age and Older |
Coronavirus disease 19 infection |
SP-0253 alone |
COVID19 Spike glycoprotein modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
GlaxoSmithKline plc, Sanofi Pasteur Inc |
|
Kenya |
2020-12-01 |
2022-04-30 |
PACTR202011523101903, VAT00002 |
Phase 2 Clinical |
Not yet recruiting |
4 |
17 Months |
34520 |
Fabienne Roche, Tirhani Maluleke, Videlis Nduba |
2020-11-17 |
| To study the effect of povidone iodine gargle and nasal drops on disease transmissibility in SARS-CoV-2 infected patients |
Coronavirus disease 19 infection |
povidone iodine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Uttar Pradesh University of Medical Sciences |
|
India |
2020-11-12 |
|
CTRI/2020/11/029063 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
32 |
Dr Amit Singh, Dr Naresh Pal Singh, Dr Pranav Sharma |
2020-11-17 |
| High chloride level, anemia and severity of COVID-19 |
Anemia, Coronavirus disease 19 infection, Hyperchloremia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kasturba Medical College and Hospital |
|
India |
2020-12-21 |
|
CTRI/2020/11/029060 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
60 |
Vedaghosh Amara |
2020-11-17 |
| COVID Phase III: A Phase III, Randomized, Double-blind, Placebo-controlled, Multicenter Study to Evaluate the Efficacy, Safety, Immunogenicity,and Lot-to-Lot consistency of BBV-152, a Whole virion Inactivated Vaccine in Adults >/= 18 Years of Age |
Coronavirus disease 19 infection |
COVAXIN alone |
COVID19 Spike glycoprotein modulator |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Bharat Biotech International Ltd, Indian Council of Medical Research |
|
India |
2020-11-11 |
|
BBIL/BBV152-C/2020 Version No: 3.0, COVID Phase III, CTRI/2020/11/028976 |
Phase 3 Clinical |
Not yet recruiting |
23 |
|
25800 |
DR T S Selvavinayagam, Dr Akshata, Dr Anjan Jyoti Talukdar, Dr C Prabhakar Reddy, Dr Chadramani Singh, Dr E Venkat Rao, Dr Krishna Mohan, Dr Laxmi S Kumari, Dr Manish Multani, Dr Mohammad Shameem, Dr N T Awad, Dr Pajanivel Ranganadin, Dr Parul Bhatt, Dr Priti Meshram, Dr R Vasudev, Dr Raghavendra Gumashta, Dr Sagar Vivek Redkar, Dr Sanjay Kumar Rai, Dr Satyajit Mohapatra, Dr Savita Verma, Dr Shashikanth Muni, Dr Shiva Narang, Dr Simmi Dube, Dr Suman Kanungo |
2020-11-13 |
| Study to assess the impact of COVID 19 infection on pulmonary function tests in children |
Coronavirus disease 19 infection |
Spirometry alone |
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Maulana Azad Medical College |
|
India |
2020-11-20 |
|
CTRI/2020/11/029058 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Dr Romit Saxena |
2020-11-13 |
| A study to assess the overall dietary practices among young and middle-aged adults pre and during COVID times |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Welcomgroup Graduate School of Hotel Administration |
|
India |
2020-11-20 |
|
CTRI/2020/11/029041 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
317 |
Dr Meenakshi Garg, Kritthika Gonella, Sudeepti Pramod Nayak |
2020-11-17 |
| Can combination of Haldi, Pomegranate and Zinger extract tablets help in reducing duration of hospital stay of mild to moderate COVID-19 patients |
Coronavirus disease 19 infection |
Dantabija + Haridra + Zingiber officinale chewable tablet alone, Standard treatment alone |
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
|
All India Institute of Medical Sciences Patna |
India |
2020-10-19 |
|
CTRI/2020/11/029038 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
100 |
Dr Yogesh Kumar |
2020-11-17 |
| Multisystemic inflammatory syndrome in children (MIS-C) in COVID pandemic |
Coronavirus disease 19 infection, Inflammatory disease |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs) |
Institute of Child Health and Hospital for Children, Madras Medical College |
|
India |
2020-11-29 |
|
CTRI/2020/11/029061 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
200 |
Dr V Poovazhagi, Prof Dr S Elilarasi |
2020-11-17 |
| ReCOVer: A study to identify the rehabilitation need in post-discharge COVID-19 survivors |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
All India Institute of Medical Sciences |
|
India |
2020-11-16 |
|
CTRI/2020/11/029036, ReCOVer |
Phase Not Applicable |
Not yet recruiting |
1 |
|
384 |
Raktim Swarnakar, S L Yadav |
2020-11-13 |
| Biological E’s novel Covid-19 vaccine of SARS-CoV-2 for protection against Covid-19 disease. |
Coronavirus disease 19 infection |
ovid-19 vaccine containing Receptor Binding Domain of SARS-CoV-2 alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Biological E Ltd |
|
India |
2020-11-16 |
|
BECT062/Covid-19-phase-I&II/CTP-01Ver: 1.1, CTRI/2020/11/029032 |
Phase 1/Phase 2 Clinical |
Recruiting |
5 |
|
360 |
Dr A Venkateshwar Rao, Dr Chandramani Singh, Dr Puneet Misra, Dr Shiv Narang, Dr Venugopal, DrSubhash Thuluva, DrTSA Kishore |
2020-11-16 |
| Blood Glucose Management in Diabetic COVID-19 Patients |
Coronavirus disease 19 infection, Diabetes mellitus |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sardar Vallabh Bhai Patel Hospital |
|
India |
2020-11-20 |
|
CTRI/2020/11/029059 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Dr Janakkumar R Khambholja, Dr Suhag B Patel |
2020-11-17 |
| Measurement of nutritional and health status of Beedi workers before and during COVID times |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Welcomgroup Graduate School of Hotel Administration |
|
India |
2020-11-20 |
|
CTRI/2020/11/029042 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
160 |
Dr Meenakshi Garg, Nithin, Shwetha Kotian |
2020-11-13 |
| Effect of corona virus disease on the mental state of anesthesiologists in India |
Coronavirus disease 19 infection, Psychiatric disorder |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Government Medical College and Hospital,Chandigarh |
|
India |
2020-11-15 |
|
CTRI/2020/11/029040 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
383 |
Dr Sanjeev Palta, Kompal Jain |
2020-11-15 |
| The performance of a novel ultra-rapid diagnostic test in the detection of COVID 19, an observational and case controlled study |
Coronavirus disease 19 infection |
ASU CV19 device alone |
|
Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Canary Health Inc |
|
India |
2020-11-18 |
|
CTRI/2020/11/029037 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
750 |
Prof Ashok Rattan |
2020-11-16 |
| Compare oxygen saturation from pulse oximetry and ABG in COVID-19 patients in ICU/HDU |
Coronavirus disease 19 infection |
pulse oximetry alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Rajarajeswari Medical college and Hospital |
|
India |
2020-11-15 |
|
CTRI/2020/11/029035 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Nadia Rose, Ramya B Sriram |
2020-11-16 |
| Multicentric, observational study on Pediatric Multisystem Inflammatory Syndrome (PMIS) related to Covid-19 |
Coronavirus disease 19 infection, Inflammatory disease |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Sir Ganga Ram Hospital |
|
India |
2020-11-19 |
|
CTRI/2020/11/029030 |
Phase Not Applicable |
Not yet recruiting |
8 |
|
100 |
Dr Bharat Mehra, Dr Chandrashekhar, Dr Dhiren Gupta, Dr Mukul Pandey, Dr Nameet Jerath, Dr Rachna Sharma, Dr Swati Kalra, Dr Vinamra Manocha |
2020-11-16 |
| A pilot study to determine health concerns developed during COVID-19 pandemic in childhood cancer survivors and siblings of Tata Memorial Hospital, who are now grown up adults |
Cancer, Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tata Memorial Hospital |
|
India |
2020-11-12 |
|
CTRI/2020/11/029029 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Dr Maya Prasad |
2020-11-15 |
| A phase III, randomized, multicenter, double-blind, placebo-controlled study to evaluate the safety and efficacy of fostamatinib in hospitalized COVID-19 patients without respiratory failure that have certain high-risk prognostic factors |
Coronavirus disease 19 infection |
fostamatinib disodium alone, standard of care alone |
Syk tyrosine kinase inhibitor |
|
Rigel Pharmaceuticals Inc |
|
|
|
|
|
Phase 3 Clinical |
Planned |
0 |
|
300 |
|
2020-11-12 |
| An open-label observational study on post covid complications and radiological pattern changes on those patients treated with ZingiVir-H |
Coronavirus disease 19 infection |
ZingiVir-H alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Pankajakasthuri herbal research foundation |
|
India |
2020-11-15 |
|
CTRI/2020/11/029025 |
Phase 2 Clinical |
Recruiting |
1 |
|
60 |
Dr J Hareendran Nair, Dr Shan Sasidharan, DrJHareendran Nair |
2020-11-17 |
| An online survey to compare the diet and physical activity management before and during COVID and how it is affected by education, occupation and income in people with diabetes belonging to middle and upper socioeconomic classes |
Coronavirus disease 19 infection, Non-insulin dependent diabetes |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Welcomgroup Graduate School of Hotel Administration |
|
India |
2020-11-20 |
|
CTRI/2020/11/029009 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
200 |
DrMeenakshi Garg, Pooja M, Susan Maria |
2020-11-16 |
| A randomized, open-label, phase IV monocentric study evaluating the clinical effect of oral immunomodulatory therapy with IMUNOR in patients with moderate COVID-19 disease |
Coronavirus disease 19 infection |
Imunor alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Thomayerova Teaching Hospital |
|
Czech Republic |
|
|
2020-002497-27, KFJ-2020-01_IMUNOR |
Phase 4 Clinical |
Recruiting |
1 |
|
60 |
Skopek -trial coordinator |
2020-11-17 |
| Signs and symptoms and outcome of babies < 28 days age admitted during pandemic in a only COVID-19 hospital in North India |
Coronavirus disease 19 infection |
|
|
Newborn Infants (up to 5 months) |
Maulana Azad Medical College |
|
India |
2020-11-17 |
|
CTRI/2020/11/029007 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1000 |
Dr Ajay Kumar, Dr Ashish Jain |
2020-11-16 |
| Radiological And Laboratory Tests Corelation With Clincial Severity Of COVID19 |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
|
|
India |
2020-11-16 |
|
CTRI/2020/11/029004 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Dr Janakkumar R Khambholja, Dr Juhi Patel |
2020-11-16 |
| Long-term lung problem of children who were affected by corona virus |
Coronavirus disease 19 infection |
Spirometry alone |
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) |
Christian Medical College, Vellore, India |
|
India |
2020-11-16 |
|
CTRI/2020/11/029026 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Dr P Madhan Kumar |
2020-11-15 |
| To assess the impact of COVID-19 on the Diet, lifestyle and physical activity of IT employees (20 to 30 years) |
Acute stress disorder, Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs) |
Welcomgroup Graduate School of Hotel Administration |
|
India |
2020-11-20 |
|
CTRI/2020/11/029012 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
300 |
Dr Meenakshi Garg, Koilakonda Sreebhavya, Shivani Endabetla |
2020-11-15 |
| To study the overall impact of consumption of non-alcoholic beverages on working from home adults, pre and during COVID times |
Acute stress disorder, Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Welcomgroup Graduate School of Hotel Administration |
|
India |
2020-11-20 |
|
CTRI/2020/11/029008 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
295 |
Dalia V R, Dr Meenakshi Garg, Shreya Majumdar |
2020-11-12 |
| KAP: Survey of Knowledge, Attitudes and Practices towards Covid-19 Pandemic |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry |
Tata Memorial Hospital |
|
India |
2020-11-20 |
|
CTRI/2020/11/029006, KAP |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1000 |
Dr Pabashi Poddar |
2020-11-12 |
| Evaluation of the effect of interferon beta-1b in the treatment of COVID-19 |
Coronavirus disease 19 infection |
Variable regimens including hydroxychloroquine , interferon beta-1b, Iran Pharmaceutical Company , lopinavir + ritonavir |
HIV protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Dezful University of Medical Sciences |
|
Iran |
2020-09-22 |
|
IR.DUMS.REC.1399.031, IRCT20200921048786N1 |
Phase 3 Clinical |
Recruiting |
1 |
|
82 |
Leila Masoudi Yekta |
2020-11-15 |
| Message Fatigue_COVID-19 |
Coronavirus disease 19 infection, Psychiatric disorder |
Online Survey alone |
|
Healthy volunteers accepted |
Institute for Health Behavioural Research (IHBR) |
|
Malaysia |
2020-11-12 |
2021-11-11 |
57105, NMRR-20-2434-57105 |
Phase Not Applicable |
Status not specified |
1 |
12 Months |
|
Mr Albeny ak Joslyn Panting, Norbaidurah binti Ithnain |
2020-11-12 |
| Correlation of Chest CT findings to the Clinical Outcomes and Final Case Classification of COVID-19 patients admitted at a tertiary hospital in the Philippines |
Coronavirus disease 19 infection |
CT scan alone |
|
|
Philippine General Hospital |
|
|
2020-06-28 |
2020-08-31 |
PHRR201023-003084 |
Phase Not Applicable |
Completed |
0 |
2 Months |
|
Jeffrey P. Apo |
2020-11-15 |
| MMD-HP: Moral Distress among Healthcare Professionals in Malaysia during the COVID-19 Pandemic |
Coronavirus disease 19 infection, Psychiatric disorder |
|
|
Healthy volunteers accepted |
HOSPITAL SERI MANJUNG |
|
Malaysia |
2020-12-01 |
2021-02-28 |
56862, MMD-HP, NMRR-20-2433-56862 |
Phase Not Applicable |
Not yet recruiting |
9 |
3 Months |
660 |
Chiew Shoen Chuen, Dr Sheila Gopal Krishnan |
2020-11-17 |
| COPOT: Ocular Trauma Trends During Covid-19 Pandemic |
Coronavirus disease 19 infection, Ocular disease |
|
|
|
Hospital Ampang |
|
Malaysia |
2020-11-23 |
2020-12-14 |
57109, COPOT, NMRR-20-2422-57109 |
Phase Not Applicable |
Status not specified |
1 |
|
|
Dr Timothy Liew Khai Wing |
2020-11-13 |
| A Study of Self-risk Behavioral Assessment of Covid-19 Disease Among Sabah State Residents |
Coronavirus disease 19 infection |
Self-risk Behavioral Assessment alone |
|
|
National Institutes of Health Malaysia |
|
Malaysia |
2020-11-13 |
2020-12-01 |
57137, NMRR-20-2415-57137 |
Phase Not Applicable |
Status not specified |
1 |
|
|
Mr Kamarul Zaman bin Salleh |
2020-11-12 |
| Prevalence of Right Ventricular Dysfunction and Its Association with COVID-19 Clinical Outcome: A Meta-Analysis |
Coronavirus disease 19 infection, Heart disease, Pulmonary artery hypertension |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universitas Airlangga |
|
Indonesia |
2020-11-11 |
|
UMIN000042424 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
1000 |
Eka Mulia |
2020-11-15 |
| Providing gold standard continuous medical education to combat COVID-19 |
Coronavirus disease 19 infection |
continuous medical education alone |
|
Healthy volunteers accepted |
Universiti Putra Malaysia |
|
Malaysia |
2020-12-01 |
2021-05-31 |
57152, NMRR-20-2410-57152 |
Phase Not Applicable |
Not yet recruiting |
1 |
6 Months |
|
Dr. Navin Kumar A/L Devaraj |
2020-11-17 |
| Prevention of Disease by SARS-CoV-2 (COVID-19) by Pre-Exposure Prophylaxis of Emtricitabine / Tenofovir disoproxil and Hydroxychloroquine in healthcare personnel: Randomized, Placebo-Controlled Clinical Trial |
Coronavirus disease 19 infection |
Variable regimens including Hydroxychloroquine , emtricitabine , tenofovir disoproxil fumarate |
DNA polymerase inhibitor, HIV-1 reverse transcriptase inhibitor, Nucleoside reverse transcriptase inhibitor |
|
Instituto Nac De Ciencias Medicas Y Nutricion Salvador Zubiran |
|
Mexico |
|
|
3419 |
Phase 3 Clinical |
Status not specified |
2 |
|
|
|
2020-11-15 |
| Evaluating the effects of Adalimumab in patients with acute respiratory distress syndrome caused by COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
Variable regimens including Lopinavir/Ritonavir (Hetero Labs Limited) , adalimumab , interferon b1a |
TNF alpha ligand inhibitor, TNF binding agent |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Shahid Beheshti University of Medical Sciences, Laser Application in Medical Sciences Research Center |
|
Iran |
2020-08-06 |
|
IR.SBMU.NRITLD.REC.1399.154, IRCT20151227025726N23 |
Phase 2/Phase 3 Clinical |
No longer recruiting |
1 |
|
60 |
Atefeh Fakharian, Farzaneh Dastan, Zahra Mirshafiei Langari |
2020-11-15 |
| Covid-19 Infection and New Onset Type 1 Diabetes |
Coronavirus disease 19 infection, Insulin dependent diabetes |
Mixed-meal tolerance test alone, SARS-Cov-2 antibody test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital of South West Jutland |
Aarhus University Hospital, Steno Diabetes Center, Steno Diabetes Center Nordjylland, Steno Diabetes Center Odense |
Denmark |
2020-11-01 |
2023-10-30 |
NCT04623697, S-20200119 |
Phase Not Applicable |
Recruiting |
1 |
35 Months |
600 |
Claus B Juhl, Claus B Juhl, MD PhD, Claus B Juhl, MD, PhD, Morten Bjerregaard-Andersen, MD PhD, Morten Bjerregaard-Andersen, MSc, PhD |
2020-11-17 |
| Melanoma Patients’ and Clinicians’ Satisfaction with Telehealth During COVID-19 |
Coronavirus disease 19 infection, Melanoma |
online survey alone, telehealth alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Melanoma Institute Australia |
|
Australia |
2020-11-27 |
2021-01-01 |
ACTRN12620001167954p |
Phase Not Applicable |
Not yet recruiting |
3 |
1 Month |
100 |
Dr Iris Bartula |
2020-11-17 |
| The adequacy of user seal checking for N95 respirators compared to formal fit testing, a multicentered, observational study |
Coronavirus disease 19 infection |
3M N95 Healthcare Particulate Respirator alone, Halyard Fluidshield N95 Particulate Filter Respirator alone, Surgical Mask 1860 Regular alone, Surgical Mask Regular alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Epworth HealthCare |
|
Australia |
2020-05-29 |
2020-11-30 |
ACTRN12620001193965, U1111-1254-8633 |
Phase Not Applicable |
Recruiting |
5 |
6 Months |
187 |
Dr Helen Cass, Dr Jonathan Barrett |
2020-11-12 |
| Inroads: An open, naturalistic trial of the Inroads program, an internet-delivered early intervention to reduce anxiety and alcohol use among young people |
Alcoholism, Coronavirus disease 19 infection, Generalized anxiety disorder, Social phobia |
automated email and text reminders alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
University of Sydney |
Australian Government Department of Health and Ageing |
Australia |
2020-11-20 |
2022-06-20 |
ACTRN12620001195943, Inroads |
Phase Not Applicable |
Not yet recruiting |
8 |
19 Months |
541 |
Dr Lexine Stapinski |
2020-11-17 |
| A Pilot Study to Assess Safety and Efficacy of SIR1-365 in Patients With Severe COVID-19 |
Cardiovascular disease, Coronavirus disease 19 infection, Renal injury, Respiratory distress syndrome |
SIR1-365 alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sironax USA |
|
|
2020-12-15 |
2021-12-15 |
NCT04622332, SIR365-US-101 |
Phase 1 Clinical |
Not yet recruiting |
0 |
12 Months |
60 |
Simon Li, MD, PhD |
2020-11-13 |
| INSPIRE: Intravenous Infusion of CAP-1002 in Patients With COVID-19 |
Coronavirus disease 19 infection |
CAP-1002 alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Capricor Inc, Capricor Therapeutics Inc |
|
US |
2020-11-20 |
2021-06-30 |
CAP-1002-COVID-19-02, INSPIRE, NCT04623671 |
Phase 2 Clinical |
Recruiting |
2 |
7 Months |
60 |
David Brabham, MD, Megan Hazelrigg, Oren Friedman, MD, Tracey S Early, BS, MA, CCRP |
2020-11-12 |
| The relationship between COVID-19 Infection and new onset and prognosis of vasospastic angina: Multicenter, prospective study |
Angina, Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Yokohama City University |
Yokohama City University Medical Center |
Japan |
2020-07-10 |
|
UMIN000042248 |
Phase Not Applicable |
Recruiting |
1 |
|
300 |
Jin Kirigaya, Yasushi Matsuzawa |
2020-11-12 |
| Efficacy of Vitamin D Treatment in Mortality Reduction Due to COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia, Vitamin D deficiency |
Hidroferol alone |
|
|
Investigation Institute Bioaraba |
Fundacion Eduardo Anitua |
Spain |
2020-11-09 |
2021-11-09 |
NCT04621058, VITD |
Phase 3 Clinical |
Recruiting |
2 |
12 Months |
108 |
Joaquin Durán, Joaquín Durán Cantolla |
2020-11-15 |
| TEMPO: Telemedical psychiatry and psychotherapy for children and adolescents during the Covid-19 pandemic: feasibility, acceptance, satisfaction and pandemic-specific mental stress |
Acute stress disorder, Coronavirus disease 19 infection |
Telemedicine psychotherapy alone |
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
University of Cologne |
Charite Universitaetsmedizin Berlin, Charité Campus Virchow-Klinikum, University Hospital RWTH Aachen, University of Gottingen |
Germany |
2020-12-01 |
|
20-1537, DRKS00023525, TEMPO, U1111-1260-8886 |
Phase 4 Clinical |
Not yet recruiting |
1 |
|
300 |
Carolina Habbel, Manfred Döpfner, Stephan Bender |
2020-11-12 |
| CARDIO-COVID: Prognostic and Clinical Impact of Cardiovascular Involvement in Patients With COVID-19 |
Coronavirus disease 19 infection, Myocardial disease |
cardiopulmonary exercise test alone, cardiovascular magnetic resonance imaging alone, chest computerized tomography scan alone, electrocardiogram analysis alone, transthoracic echocardiogram analysis alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Istituto Clinico Humanitas |
Centro Cardiologico Monzino Spa - Irccs, IRCCS Policlinico San Donato, Istituti Clinici Scientifici Maugeri Spa Sb, Istituto Auxologico Italiano |
Italy |
2020-10-01 |
2021-10-01 |
CARDIO-COVID, CARDIOCOVID, NCT04624503 |
Phase Not Applicable |
Recruiting |
5 |
12 Months |
500 |
Gianluigi Condorelli, Prof, Giulio Stefanini, Giulio Stefanini, Prof, Giulio Stefanini, Prof., Luigi Badano, Prof., Marco Guazzi, Prof, Piergiuseppe Agostoni, Prof., Sivlia Priori, Prof.ssa |
2020-11-12 |
| PIVOT With MI: Presumptively Initiating Vaccines and Optimizing Talk With Motivational Interviewing |
Coronavirus disease 19 infection |
motivational interviewing intervention (PIVOT with MI) alone |
|
Newborn Infants (up to 5 months) |
University of Colorado at Denver and Health Sciences Center |
Eunice Kennedy Shriver National Institute of Child Health & Human Development, National Institutes of Health, Portland State University, Seattle Children's Hospital, The Childrens Mercy Hospital, University of Missouri, University of Washington |
US |
2019-09-01 |
2023-07-31 |
17-1274, 1R01HD093628-01A1, NCT03885232, PIVOT With MI |
Phase Not Applicable |
Recruiting |
2 |
47 Months |
1000 |
Douglas Opel, MD, MPH, Sean O'Leary, MD, MPH |
2020-11-11 |
| A clinical trial of MP-1032 (inhalation, COPD), MetrioPharm for the treatment of covid-19 |
Coronavirus disease 19 infection |
MP-1032 (inhalation, COPD), MetrioPharm alone |
Superoxide dismutase stimulator |
|
MetrioPharm AG |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-11-11 |
| CovIdentify: Using Smart Watches to Detect and Monitor COVID-19 |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Duke University |
|
US |
2020-04-02 |
2022-02-01 |
CovIdentify, NCT04623047, PRO00106404 |
Phase Not Applicable |
Recruiting |
1 |
22 Months |
100000 |
Chris Woods, Jessilyn Dunn, Ryan Shaw |
2020-11-13 |
| Neurocognitive Functions of Recovered COVID-19 Patients |
Coronavirus disease 19 infection, Inflammatory disease, Psychiatric disorder |
Trier Social Stress Test alone, oral calculation test alone, speech test alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
National Institute on Drug Dependence |
The Sixth Hospital of Peking University (Institute of Mental Health), Wuhan Wuchang Hospital |
China |
2020-07-10 |
2020-12-10 |
NCT04622748, NIDD-2020-NEUROCOGNITION |
Phase Not Applicable |
Recruiting |
1 |
5 Months |
160 |
Guofu Huang, Dr, Lin Lu, Dr., Ping Wu, Dr. |
2020-11-15 |
| A Virtual Prospective Study Exploring Activity Trackers and COVID-19 Infections |
Coronavirus disease 19 infection |
Empatica E4 alone, Garmin vivosmart 4 alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Evidation Health Inc |
Bill & Melinda Gates Foundation, Biomedical Advanced Research and Development Authority (BARDA), Eli Lilly & Co, US Department of Defense, Vir Biotechnology Inc |
US |
2020-11-30 |
2021-05-31 |
COVID SIGNALS, NCT04623138 |
Phase Not Applicable |
Not yet recruiting |
1 |
6 Months |
950 |
Ernesto Ramirez, PhD, Joyce HN Nortey, MPH, MSBH, Luca Foschini, PhD |
2020-11-13 |
| Exercise Influence on COVID-19 |
Coronavirus disease 19 infection |
physical exercise alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universidad De Salamanca |
|
Spain |
2020-12-04 |
2021-04-04 |
08112020, NCT04624048 |
Phase Not Applicable |
Not yet recruiting |
1 |
4 Months |
30000 |
CARLOS MARTIN-SANCHEZ, DOCTOR |
2020-11-14 |
| Thromboprophylaxis for Patients in ICU With COVID-19 |
Coronavirus disease 19 infection, Thrombosis |
low molecular weight heparin alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Instituto de Investigacion Sanitaria La Fe |
Clinica Universidad de Navarra, Hosp Univ & Politecn La Fe, Hospital Clinic of Barcelona, Hospital Universitario Doctor Peset, Hospital de Cruces, Hospital de Sant Joan Despi Moises Broggi, La Paz University Hospital (Madrid) |
Spain |
2020-03-01 |
2020-11-30 |
NCT04623177, REGCOVID-19 |
Phase Not Applicable |
No longer recruiting |
31 |
9 Months |
950 |
Raquel Ferrandis, MD |
2020-11-13 |
| Clarithromycin Versus Azithromycin in Treatment of Mild COVID-19 Infection |
Coronavirus disease 19 infection |
clarithromycin alone, symptomatic treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
South Valley University |
|
Egypt |
2020-04-01 |
2020-07-30 |
NCT04622891, SVU-MED-CHT019-420860 |
Phase 2 Clinical |
Completed |
1 |
3 Months |
300 |
Alaa Rashad, MD |
2020-11-14 |
| Clinical Role of Testosterone and Dihydrotestosterone and Which of Them Should be Inhibited in COVID-19 Patients - A Double-edged Sword? |
Coronavirus disease 19 infection, Respiratory failure |
13-cis retinoic acid plus testosterone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Kafrelsheikh University |
|
Egypt |
2020-11-30 |
2021-12-31 |
NCT04623385, SARS -2 |
Phase 4 Clinical |
Not yet recruiting |
1 |
13 Months |
1000 |
Mahmoud Elkazzaz, B.Sc in Biochemistry, Mahmoud Ramadan mohamed Elkazzaz |
2020-11-14 |
| RIVERSIDE: Evaluation of the use of video consultation in rheumatology in the context of the COVID-19 pandemic |
Coronavirus disease 19 infection |
video consultation alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Universitätklinikum Düsseldorf |
|
Germany |
2020-11-15 |
|
DRKS00023430, IT-TEMP-36, RIVERSIDE |
Phase Not Applicable |
Not yet recruiting |
1 |
|
300 |
Jutta Richter |
2020-11-13 |
| PROFACT-01: An Outpatient Study Investigating Non-prescription Treatments for COVID-19 |
Coronavirus disease 19 infection |
chlorine dioxide aqueous solution alone, zinc acetate alone, Variable regimens including Lactoferrin , chlorine dioxide aqueous solution , famotidine , green tea extract , zinc acetate |
Histamine H2 receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
|
|
Pakistan |
2020-11-09 |
2021-01-31 |
NCT04621149, PROFACT-01, PROFACT-01 |
Phase 2 Clinical |
Not yet recruiting |
1 |
2 Months |
120 |
Jonathan Murphy, MD, MD(H), Mitchell B Liester, MD |
2020-11-14 |
| Longitudinal COVID-19 Antibody Testing in Indiana University Undergraduate Students |
Coronavirus disease 19 infection |
SARS-CoV-2 IgM/IgG serological test alone, SARS-CoV-2 rapid assay kit (colloidal gold) alone, personal protective behavior alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Indiana University |
|
US |
2020-09-14 |
2020-12-31 |
2008293852, NCT04620798 |
Phase Not Applicable |
No longer recruiting |
1 |
3 Months |
1700 |
Molly Rosenberg, PhD |
2020-11-15 |
| Effectiveness and safety of plasma convalescent therapy in patients with COVID-19 |
Coronavirus disease 19 infection |
convalescent plasma alone |
|
Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ministry of Research and Technology |
|
Indonesia |
2020-04-26 |
2020-12-13 |
003, ISRCTN16842454 |
Phase 2 Clinical |
Recruiting |
1 |
7 Months |
5 |
Dr Santosa |
2020-11-14 |
| CCP-Cancer UK: Companion study to educate and inform practice and guidelines regarding COVID-19 infection in cancer patients |
Cancer, Coronavirus disease 19 infection |
|
|
Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The Clatterbridge Cancer Centre NHS Foundation Trust |
Clatterbridge Cancer Research Trust, National Institute for Health Research (NIHR), United Kingdom Research & Innovation |
UK |
2020-08-11 |
2022-08-24 |
CCP-Cancer UK, CPMS 46602, IRAS 285044, ISRCTN15019599 |
Phase Not Applicable |
Recruiting |
2 |
24 Months |
9000 |
Dr Coordinator |
2020-11-13 |
| Pilot, Feasibility Study of Remote Problem Management Plus for Adults Affected by COVID-19 (PM+) |
Coronavirus disease 19 infection, Psychiatric disorder |
Problem Management Plus low-intensity psychological intervention alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
New School University |
George Washington University |
US |
2020-11-30 |
2021-09-30 |
2020-91-PM+, NCT04617262 |
Phase Not Applicable |
Not yet recruiting |
1 |
10 Months |
100 |
Adam Brown, PhD, Brandon Kohrt, MD, PhD, Kendall Pfeffer, MEd, MA |
2020-11-14 |
| TTTC: Taking Time to Connect: A Study of Programs for Hispanic Mothers Diagnosed With Cancer and Their Children |
Cancer, Coronavirus disease 19 infection |
Conexiones telephone sessions alone |
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), European Ancestry |
New Mexico State University |
Fred Hutchinson Cancer Research Center, National Cancer Institute, University of Washington |
US |
2019-04-16 |
2021-08-31 |
17894, NCT03951454, TTTC |
Phase Not Applicable |
Recruiting |
3 |
28 Months |
156 |
Frances M Lewis, PhD, Rebecca Palacios, PhD |
2020-11-14 |
| A Pilot Study on Efficacy and Safety of Ayurveda Combination in Patients With Mild-to-Moderate COVID-19 |
Coronavirus disease 19 infection |
Shanshamani Vati Plus alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Aarogyam UK |
All India Institute of Ayurveda, Government of India, Ministry of Ayush, Warwick University |
UK |
2020-10-08 |
2020-11-03 |
AU/WU/ 06, NCT04621903 |
Phase Not Applicable |
Completed |
1 |
|
26 |
Dipa Modi, Neha Sharma, Tanuja Nesari, Vishwesh Kulkarni |
2020-11-14 |
| plasmApuane CoV-2: Efficacy and Safety of Immune Covid-19 Plasma in Covid-19 Pneumonia in Non ITU Patients |
Coronavirus disease 19 infection, Viral pneumonia |
immune plasma infusion alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
L'Azienda USL Nord Ovest |
|
Italy |
2020-05-15 |
2020-12-31 |
ATNONORDOVEST, NCT04622826, plasmApuane CoV-2 |
Phase 2 Clinical |
Recruiting |
1 |
7 Months |
50 |
Antonella Vincenti, Mirko lombardi, antonella vincenti, mirko lombardi |
2020-11-14 |
| Mental Health in Communities Affected by COVID-19 in Uganda |
Coronavirus disease 19 infection, Drug dependence, Generalized anxiety disorder, Major depressive disorder, Post traumatic stress disorder, Psychiatric disorder |
psycho-education intervention alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Makerere University |
|
Uganda |
2020-11-01 |
2021-07-30 |
INTEGRATION OF MENTAL HEALTH, NCT04616989 |
Phase Not Applicable |
Not yet recruiting |
1 |
8 Months |
840 |
Dickens Akena, PhD |
2020-11-13 |
| Orthopedic Conservative Treatment in the Time of Covid-19 Pandemic |
Bone injury, Coronavirus disease 19 infection |
orthopedic conservative treatment alone |
|
Elderly Adults (80 and over) |
Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization |
|
Turkey |
2020-03-11 |
2020-11-01 |
NCT04623346, TREATMENT IN THE TIME OF COVID |
Phase Not Applicable |
No longer recruiting |
1 |
7 Months |
262 |
Bulent KARSLIOGLU |
2020-11-13 |
| Use Acetyl L-Carnitine in Patients With Covid-19 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
acetyl L-Carnitine alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone Palermo |
|
Italy |
2020-12-15 |
2021-07-31 |
20201109, NCT04623619 |
Phase Not Applicable |
Not yet recruiting |
1 |
7 Months |
100 |
Antonio Cascio, MD, PhD |
2020-11-13 |
| A clinical trial of SARS-CoV-2-RBD nanoparticle vaccine, University of Washington for the potential prevention of COVID-19 infection |
Coronavirus disease 19 infection |
SARS-CoV-2-RBD nanoparticle vaccine, University of Washington alone |
|
|
Washington University School of Medicine, US |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-11-11 |
| COMPVID STUDY: Randomized, controlled study of inflammation inhibition in the treatment of pneumonia by the SARS-Cov-2 virus |
Coronavirus disease 19 infection, Viral pneumonia |
nomacopan alone |
Complement C5 factor inhibitor, Leukotriene BLT receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Eduardo de Menezes, Universidade Federal de Minas Gerais |
|
Brazil |
2020-08-19 |
2021-01-31 |
35247020.9.0000.5124, 4.165.354, COMPVID STUDY, RBR-88bjcv, U111112603293 |
Phase 2 Clinical |
Recruiting |
1 |
5 Months |
|
Glauciene Prado Alves Prado Alves, Mauro Martins Teixeira |
2020-11-13 |
| AEROBI - COVID: Effect of Moderate Physical Training on a bicycle associated with altitude simulation on the health status of people recovered from COVID-19 |
Coronavirus disease 19 infection |
hypoxia alone, normoxia alone, recovery alone, training alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Escola de Educação Física e Esporte de Ribeirão Preto, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, University of Sao Paulo |
Fundacao de Amparo a Pesquisa do Estado Sao Paulo |
Brazil |
2020-09-11 |
2021-04-30 |
33783620.6.0000.5659, 33783620.6.3001.5403, AEROBI - COVID, RBR-5d7hkv, U1111-1260-7479 |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
80 |
Atila Alexandre Trapé |
2020-11-16 |
| Hyperbaric Oxygen for COVID-19 Patients With Moderate to Severe Respiratory Distress |
Coronavirus disease 19 infection, Respiratory distress syndrome |
Standard of Care alone, hyperbaric oxygen alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
NYU Langone Health |
|
US |
2020-11-16 |
2021-12-15 |
20-00897, NCT04619719 |
Phase 2 Clinical |
Not yet recruiting |
2 |
13 Months |
600 |
David Lee, MD, Sandra Wainwright, MD, Scott Gorenstein, MD |
2020-11-12 |
| CortiCORONA: Biomarkers for Dexamethasone Response in Sars-Cov-2/COVID-19 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
dexamethasone alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital, Montpellier |
|
France |
2020-11-05 |
2021-11-30 |
2020-A0206-33, CortiCORONA, NCT04619693, PHRCI-20-013, RECHMPL20_0292 |
Phase Not Applicable |
Not yet recruiting |
2 |
12 Months |
100 |
Alain Makinson, MD, Boris Jung, MD, PhD, Bourdin Arnaud, MD, PhD, Camille Roubille, MD, Clement Boissin, MD, Clément Boissin, MD, Clément Le Bihan, MD, David Morquin, MD, Edouard Tuaillon, MD, PhD, Jacques Reynes, MD, PhD, Jean-Pierre Mallet, MD, Jérémy Charriot, MD, Kada Klouche, MD, PhD, Khuder Alagha, MD, Nathalie Pansu, MD, Pierre Fesler, MD, Sébastien Bommart, MD, PhD, Vincent Le Moing, MD |
2020-11-12 |
| COVISTRESSNutr: Influence of the COVID-19 Pandemic on Stress and Eating Habits |
Acute stress disorder, Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Clermont-Ferrand |
|
France |
2020-04-01 |
2025-12-31 |
2020 COVISTRESS NUTRITION, COVISTRESSNutr, NCT04621084 |
Phase Not Applicable |
Recruiting |
1 |
69 Months |
1000 |
Frederic DUTHEIL, Lise Laclautre, lise laclautre |
2020-11-16 |
| Hydroxychloroquine, Azithromycin and Zinc for the Treatment of COVID-19 in the Outpatient Setting |
Coronavirus disease 19 infection |
Variable regimens including azithromycin , hydroxychloroquine , zinc sulfate |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
St. Francis Hospital, New York |
|
US |
2020-11-30 |
2021-05-31 |
20-19, NCT04621461 |
Phase 4 Clinical |
Not yet recruiting |
1 |
6 Months |
750 |
Avni Thakore, MD, Elizabeth Haag, RN, Elizabeth S Haag, RN |
2020-11-11 |
| Effect of a Cloth Mask Physical Exercise session on Cardiovascular health, Feeling and Exercise Effort, Oxygen Quantity and Jumping Performance: Recommendation for Physical Mask Exercise during and after the COVID-19 global outbreak |
Cardiovascular disease, Coronavirus disease 19 infection |
cloth mask alone, exercise alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Universidade Federal do Rio Grande do Norte |
|
Brazil |
2020-11-02 |
|
RBR-9b6kvp, U1111-1259-3641 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
30 |
Phelipe Wilde de Alcântara Varela |
2020-11-11 |
| Effectiveness of a mouthwash and toothpaste containing PHTALOX in controlling symptoms of COVID-19 and flu |
Coronavirus disease 19 infection, Influenza virus infection |
Kit for oral care alone, PHTALOX alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Instituto Federal do Paraná - IFPR |
|
Brazil |
2020-11-01 |
|
35530020.1.0000.8156, 4.355.065, RBR-8x8g36, U1111-1260-4839 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
500 |
Marcelo Lupion Poleti |
2020-11-12 |
| COnV-ert: Plasma for Early Treatment in Non-hospitalized Mild or Moderate COVID-19 Patients |
Coronavirus disease 19 infection, Lower respiratory tract infection |
methylene blue treated convalescent anti-SARS-CoV-2 plasma alone, standard medical treatment alone |
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fundacio Lluita Contra La Sida |
Banc De Sang I Teixits, Germans Trias i Pujol Hospital, Grifols Biologicals Inc, irsiCaixa Foundation |
Spain |
2020-10-30 |
2021-10-31 |
CONV-ERT, COnV-ert, NCT04621123 |
Phase 2 Clinical |
Recruiting |
1 |
12 Months |
474 |
ORIOL Mitjà Villar, MD,PhD, ORIOL Mitjà Villar, MD,Phd, Oriol Mitjà Villar, PhD, MD |
2020-11-13 |
| MOMA: Measurement of the effect of mouthwash against COVID-19 |
Coronavirus disease 19 infection |
Dentyl mouthwash alone, Ultradex alone, povidone-iodine alone |
|
|
Cardiff University |
Venture Life Ltd |
UK |
2020-05-20 |
2020-12-27 |
IRAS 285247, ISRCTN25647404, MOMA |
Phase 2 Clinical |
Recruiting |
3 |
7 Months |
104 |
Prof Thomas |
2020-11-13 |
| Innovation of Audio-Visual Triage System in Combating the Spread of COVID-19 Infection and Its Efficacy: A Novel Strategy |
Anxiety disorder, Coronavirus disease 19 infection |
audio-visual triage system alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs) |
University of Lahore, Main Campus |
|
Pakistan |
2020-03-21 |
2020-04-28 |
IRBEC/BIH/013-2020, NCT04621214 |
Phase Not Applicable |
Completed |
1 |
1 Month |
60 |
Dr Muhammad Mansoor Hafeez |
2020-11-13 |
| PROVID-19: Efficacy of Probiotics in Reducing Symptoms of COVID-19 |
Coronavirus disease 19 infection |
probiotic intake alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre hospitalier universitaire de Sherbrooke |
Lallemand Health Solutions |
Canada |
2020-11-16 |
2021-03-31 |
2021-3700, NCT04621071, PROVID-19 |
Phase Not Applicable |
Not yet recruiting |
1 |
4 Months |
84 |
Audrey Hamel-Thibault, MSc, Blanche Senicourt, PhD, Jean-Charles Pasquier, Dr, Jean-Charles Pasquier, MD, PhD |
2020-11-11 |
| Investigating effect of Spirulina dietary supplementation on COVID-19 disease outcomes in patients admitted to Intensive Care Units |
Coronavirus disease 19 infection |
routine medication alone, spirulina supplement alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Islamic Azad University |
|
Iran |
2020-11-21 |
|
IR.IAU.PS.REC.1399.063, IRCT20200720048139N1 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
138 |
Farshad Hashemian, Mahdi Shadnoush, Monireh Hatami |
2020-11-12 |
| ENDCOV-I: The Study Will Evaluate the Use of Nintedanib in Slowing Lung Fibrosis in Patients With Pulmonary Infiltrates Related to COVID-19 |
Coronavirus disease 19 infection, Interstitial lung disease, Pulmonary fibrosis |
nintedanib alone |
CSF-1 antagonist, FGF receptor antagonist, FGF1 receptor antagonist, FGF2 receptor antagonist, FGF3 receptor antagonist, Flt3 tyrosine kinase inhibitor, Lck tyrosine kinase inhibitor, Lyn tyrosine kinase inhibitor, PDGF receptor alpha antagonist, PDGF receptor antagonist, PDGF receptor beta antagonist, Src tyrosine kinase inhibitor, VEGF receptor antagonist, VEGF-1 receptor antagonist, VEGF-2 receptor antagonist, VEGF-3 receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Mount Sinai Medical Center |
Boehringer Ingelheim International GmbH |
US |
2020-11-30 |
2021-07-31 |
ENDCOV-I, GCO 20-2147, NCT04619680 |
Phase 4 Clinical |
Recruiting |
2 |
8 Months |
120 |
Aditi Mathur, MD, Alona Lansky, Jigna Zatakia, Maria Padilla, MD |
2020-11-13 |
| Seroprevalence of COVID-19 antibodies |
Coronavirus disease 19 infection |
|
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Kalinga Institute of Medical Sciences |
|
India |
2020-11-15 |
|
CTRI/2020/11/028967 |
Phase Not Applicable |
Not yet recruiting |
6 |
|
100 |
Ramnath Misra |
2020-11-11 |
| A study to observe the trend of SARS-CoV-2, Dengue and Chikungunya infection transmission in the general population |
Chikungunya virus infection, Coronavirus disease 19 infection, Dengue virus infection |
|
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Biotechnology Industry Research Assistance Council |
|
India |
2020-11-18 |
|
CTRI/2020/11/028968 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
5000 |
DrYuvarajJayaraman |
2020-11-12 |
| Effect of Group Otago Exercise Program on Cognitive Frailty in the Nursing Home: a Randomized Controlled Trial |
Cognitive disorder, Coronavirus disease 19 infection |
Otago exercise alone |
|
Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The Second XiangYa Hospital of Central South University, Xiangya School of Medicine of Central South University |
Health and Family Planning Commission of Hunan Province |
China |
2020-06-01 |
2020-10-13 |
ChiCTR2000039592 |
Phase 0 Clinical |
Completed |
1 |
4 Months |
62 |
Chen Xi |
2020-11-12 |
| Effect Of COVID-19 on breast cancer treatment and its outcome |
Breast tumor, Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tata Memorial Hospital |
|
India |
2020-11-16 |
|
CTRI/2020/11/028969 |
Phase Not Applicable |
Not yet recruiting |
2 |
|
900 |
Dr Jince Mary Mathew, Dr Rajiv Sarin |
2020-11-11 |
| A clinical trial to assess JNJ-78436735 in youths aged 12 to 18 for COVID-19 |
Coronavirus disease 19 infection |
JNJ-78436735 alone |
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Johnson & Johnson |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-11-11 |
| Intubation with VieScope versus Videolaryngoskopy in complete personal protecion gear in asimulated COVID-19-Patient - A randomized, controlled trial |
Coronavirus disease 19 infection |
Glidescope alone, VieScope alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
University of Cologne |
|
Germany |
2020-11-15 |
|
20-1465, DRKS00023406 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
35 |
Hannes Ecker |
2020-11-12 |
| COVID-19 Stress, Depression, and Anxiety Among Health Care Workers in Selangor Hospitals |
Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
HOSPITAL TENGKU AMPUAN RAHIMAH KLANG |
|
Malaysia |
2020-11-09 |
2022-12-31 |
56884, NMRR-20-2388-56884 |
Phase Not Applicable |
Not yet recruiting |
1 |
25 Months |
|
Dr Natasha Subhas |
2020-11-15 |
| Evaluation of the combined effect of Hesperidin,Artemisinin- Artemisia annua, Noscapine, N-acetylcysteine, Resveratrol supplements and high dose of vitamin C on treatment, clinical symptoms of non-hospitalization and hospitalization patients with symptomatic COVID-19 |
Coronavirus disease 19 infection |
Variable regimens including Artemisia annua - Artemisinin, Longlifenutri , N-acetyl cysteine, Osvah , hesperidin, Swanson , noscapine, Faran Shimi , resveratrol, A Squard , vitamin C, Daroupakhsh |
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kerman University of Medical Sciences |
|
Iran |
2020-10-07 |
|
IR.SIRUMS.REC.1399.033, IRCT20181030041504N1 |
Phase 3 Clinical |
No longer recruiting |
1 |
|
100 |
Dr. Masoomeh Mohamadpour, Dr.Ali,Amjadi, دکتر علی امجدی |
2020-11-13 |
| The Prevalence of Malnutrition among Adult Patients with the Coronavirus Disease 2019 (COVID 19) in a Tertiary Government Hospital |
Coronavirus disease 19 infection, Malnutrition |
|
|
|
Philippine General Hospital |
|
Philippines |
2020-07-14 |
2020-09-15 |
PHRR201109-003131 |
Phase Not Applicable |
Completed |
1 |
2 Months |
|
Blessie Marie B. Perez, Harold Henrison Chiu, MD, Lia Aileen M. Palileo-Villanueva, MD, Ramon B. Larrazabal Jr. |
2020-11-13 |
| Knowledge and attitudes of healthcare personnel towards COVID-19 disease and infection control strategies in a tertiary-level government hospital and COVID-19 referral center in the Philippines |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted |
Philippine General Hospital |
|
Philippines |
2020-06-01 |
2020-12-01 |
PHRR201109-003132 PHRR201109-003132 |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
|
Janine G. Mendoza, Maria Sonia Salamat, MD, Nigel Cortez Santos |
2020-11-11 |
| Determination the therapeutic effect of Ivermectin and Sovodak on patients infected with COVID-19 |
Coronavirus disease 19 infection |
standard regimen therapy alone, Sovodak plus ivermectin |
Chloride channel modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Akam Tejarat Fartak Farasoo |
|
Iran |
2020-10-16 |
|
IR.QUMS.REC.1399.228, IRCT20200408046987N2 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
|
150 |
Dr. Aliakbar Karami, Dr Elham Zsabganeh, Morteza Shakhs Niaee, Nematollah Gheibi |
2020-11-12 |
| Effect of Dexamethasone on treatment of COVID-19 |
Coronavirus disease 19 infection |
dexamethasone alone, standard treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tehran University of Medical Sciences |
|
Iran |
2020-09-11 |
|
IR.TUMS.MEDICINE.REC.1399.432, IRCT20201015049030N1 |
Phase 2 Clinical |
Recruiting |
4 |
|
200 |
Ali Asadolahi Amin, Mahdi Mahmoudi, Maryam Akhtari, Mohamadreza Salehi, Mohammad Ali Sahraian, Mojtaba Hedayat Yaghoobi, Saeed Reza Jamali Moghadm |
2020-11-11 |
| Effect of recombinant erythropoietin in COVID-19 patients |
Coronavirus disease 19 infection, Viral pneumonia |
recombinant erythropoietin (r-EPO) alone, standard care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
All India Institute of Medical Sciences |
|
India |
2020-11-06 |
|
CTRI/2020/11/028959 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
40 |
Ashutosh kumar singh, Prof Anjan Trikha |
2020-11-11 |
| Psychological burden in COVID-19 |
Anxiety disorder, Coronavirus disease 19 infection, Depression, Somatization disorder |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
All India Institute of Medical Sciences |
|
India |
2020-11-10 |
|
CTRI/2020/11/028954 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Bichitra Nanda Patra |
2020-11-10 |
| FUSIC: Ultrasonography in COVID-19 patients with a focus on possible clinical diagnosis and management decisions |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Pushpagiri Institute of Medical Sciences & Research Centre |
|
India |
2020-11-19 |
|
CTRI/2020/11/028938, FUSIC |
Phase Not Applicable |
Not yet recruiting |
1 |
|
44 |
Manju Mathew |
2020-11-10 |
| Outpatient Treatment With CoVid-19 With Prexablu |
Coronavirus disease 19 infection |
NocUlite alone, low level light therapy alone, methylene blue (Prexablu) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Instituto De Seguridad Y Servicios Sociales De Los Trabajadores Del Estado |
|
Mexico |
2020-10-12 |
2020-12-30 |
064.I.2020, NCT04619290 |
Phase 1 Clinical |
Recruiting |
1 |
2 Months |
46 |
M. Eunice Rodríguez Arellano, Martha E. Rodríguez Arellano, MD, Paula Costa Urrutia, PhD, Robin Messier |
2020-11-13 |
| RE-CoV-ERY: Post-intensive Care Follow-up of Patients Hospitalized for an Acute Respiratory Distress Syndrome Caused by COVID-19 |
Coronavirus disease 19 infection, Post traumatic stress disorder, Respiratory distress syndrome |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire de Toulouse |
|
France |
2020-07-27 |
2022-07-31 |
NCT04619368, RC31/20/0219, RE-CoV-ERY |
Phase Not Applicable |
Recruiting |
1 |
24 Months |
100 |
Fanny BOUNES, Fanny BOUNES, PH |
2020-11-11 |
| A trial to evaluate an at-home rapid antigen test for COVID-19 |
Coronavirus disease 19 infection |
at-home rapid antigen test alone |
|
|
Gauss Surgical |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
159 |
|
2020-11-10 |
| Physical Activity a Vital Sign? 40 Steps to Safety Test for Patients With COVID-19 |
Coronavirus disease 19 infection |
40-steps test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Betsi Cadwaladr University Health Board |
Oxford Brookes University |
UK |
2020-11-03 |
2021-11-03 |
283998, NCT04618835 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
1000 |
Christian Subbe, Christian Subbe, DM, Dr Christian P Subbe, Laura Langshaw |
2020-11-12 |
| COVISTRESSWork: Influence of the COVId-19 Pandemic on Stress of Occupational Health Workers |
Acute stress disorder, Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Clermont-Ferrand |
|
France |
2020-06-01 |
2025-12-21 |
2020 COVISTRESS WORK, COVISTRESSWork, NCT04619576 |
Phase Not Applicable |
Recruiting |
1 |
66 Months |
1000 |
Frederic DUTHEIL, Lise Laclautre, lise laclautre |
2020-11-11 |
| Safety and Immunogenicity of COVI-VAC, a Live Attenuated Vaccine Against COVID-19 |
Coronavirus disease 19 infection |
COVI-VAC alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs) |
Codagenix Inc |
|
UK |
2020-12-31 |
2022-05-31 |
CDX-COV-001, NCT04619628 |
Phase 1 Clinical |
Not yet recruiting |
1 |
17 Months |
48 |
Daryl Bendel, MD, Kingsley Eze, Sybil Tasker, MD, MPH |
2020-11-17 |
| Ultramicronized Palmitoylethanolamide (PEA) Treatment in Hospitalized Participants With COVID-19 |
Coronavirus disease 19 infection |
palmidrol + morphine (ultramicronized, severe chronic pain), FSD Pharma alone, standard of care alone |
Cannabinoid CB2 receptor modulator, Opioid receptor mu agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
FSD Pharma Inc |
|
|
2020-11-15 |
2021-12-05 |
FSD201-03, NCT04619706 |
Phase 2a Clinical |
Not yet recruiting |
0 |
12 Months |
350 |
FSD BioSciences Head of Clinical Research |
2020-11-10 |
| Surfactant Protein D Levels in Covid-19 Infection: Case-Control Study |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kafkas University |
|
Turkey |
2020-10-13 |
2020-11-02 |
CLINICAL-1, NCT04618861 |
Phase Not Applicable |
Completed |
1 |
|
127 |
Ramazan Sbirli |
2020-11-11 |
| A Single-Dose Study to Determine the Safety and Tolerability of Intranasal REVTx-99 in Healthy Adult Volunteers |
Coronavirus disease 19 infection |
REVTx-99 alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Linear Clinical Research Limited, Statistical Revelations |
|
Australia |
2020-11-12 |
2020-12-24 |
2020-08-796, ACTRN12620001104943, ANZCTR380621, RVL-NHV01 |
Phase 1 Clinical |
Not yet recruiting |
1 |
1 Month |
32 |
Carol Odle, George Tidmarsh, Jasmine Williams |
2020-11-10 |
| ASK: Improving access to kidney transplantation |
Coronavirus disease 19 infection, Kidney transplantation |
Clinician letter alone, Home-based patient and family education and engagement alone, Remote virtual ‘visit’/link alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Bristol, Wellcome Trust |
Wellcome Trust |
UK |
2018-01-01 |
2023-02-01 |
, SPONSOR'S NUMBER 2020-4883, WT 214554/Z/18/Z, ASK, IRAS 287507, ISRCTN10989132 |
Phase Not Applicable |
Not yet recruiting |
0 |
61 Months |
60 |
Dr Bailey |
2020-11-17 |
| COKITS: Screening for COVID-19 in Teachers, Childcare Educators, Pupils and Preschoolers |
Coronavirus disease 19 infection |
Anti-SARS-CoV-2 antibody testing alone, SARS-CoV-2 PCR test alone |
|
Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
University Medicine Greifswald |
Government of Mecklenburg-Western Pomerania, Landesamt für Gesundheit und Soziales M-V |
Germany |
2020-11-04 |
2021-03-31 |
BB 179/20, COKITS, NCT04619407 |
Phase Not Applicable |
Recruiting |
1 |
4 Months |
300 |
Karsten Becker, Prof. Dr., Lena Ulm, Dr., Nils-Olaf Hübner, Prof. Dr. |
2020-11-11 |
| A phase II clinical trial of 7HP-349 in combination with COVID-19 vaccine for the treatment of patients with COVID-19 infection |
Coronavirus disease 19 infection |
7HP-349 plus COVID-19 vaccine |
CD11a agonist, CD49d agonist, ICAM-1 stimulator, Integrin agonist, Vascular cell adhesion protein 1 agonist |
|
7 Hills Pharma Llc |
|
|
|
|
|
Phase 2 Clinical |
Planned |
0 |
|
|
|
2020-11-13 |
| A Comparison of Fiberoptic Endotracheal Intubation Between the Intubating Laryngeal Tube Suction and the LMA Protector |
Coronavirus disease 19 infection, Respiratory disease |
LMA Protector alone, disposable intubating laryngeal tube suction device alone, endotracheal tube (VBM Medizintechnik GmbH) alone, fiberscope (Karl Storz) alone, Variable regimens including fentanyl , nitrous oxide , oxygen , propofol, AstraZeneca/Fresenius , rocuronium bromide , sevoflurane |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
B'nai Zion Medical Center |
|
Israel |
2020-11-01 |
2020-12-30 |
NCT04618926, PROTECTOR |
Phase Not Applicable |
Not yet recruiting |
1 |
1 Month |
80 |
LUIS.GAITINI, Luis Gaitini, M.D., Mostafa Somri, M.D. |
2020-11-13 |
| Effect of COVID-19 Pandemic on Vaccination Compliance |
Coronavirus disease 19 infection |
|
|
Infants (6-23 months), Preschool Children (2-5 yrs) |
Assiut University |
|
Egypt |
2021-04-01 |
2022-05-01 |
EFFECT OF COVID ON VACCINATION, NCT04618796 |
Phase Not Applicable |
Not yet recruiting |
1 |
13 Months |
100 |
Gehad Gamal Ahmed, Gehad Gamal, resident doctor, Ismail lotfy, associated professor, Mohamed Hamdy, professor |
2020-11-10 |
| A Phase II Clinical Trial of Influenza virus Vector COVID-19 Vaccine for intranasal Spray (DelNS1-2019-nCoV-RBD-OPT1) |
Coronavirus disease 19 infection, Viral pneumonia |
COVID-19 XWG-03 alone |
COVID19 Spike glycoprotein modulator |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Beijing Wantai Biological Pharmacy Enterprise Co Ltd, Jiangsu Province Centers for Disease Control and Prevention |
|
China |
2020-11-17 |
2021-12-17 |
ChiCTR2000039715 |
Phase 2 Clinical |
Not yet recruiting |
1 |
13 Months |
720 |
Fengcai Zhu, Xiangzhong Ye |
2020-11-17 |
| The impact of COVID-19 on selective orthopedic surgery in Shanghai Sixth People's Hospital |
Coronavirus disease 19 infection |
selective orthopedic surgery alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shanghai Sixth People’s Hospital |
|
China |
2020-11-08 |
2020-12-08 |
ChiCTR2000039711 |
Phase Not Applicable |
Recruiting |
1 |
1 Month |
2000 |
Cunyi Fan, Tengfei Lou |
2020-11-11 |
| ProMusik: Prospective, cohort study on the incidence of SARS-CoV-2-infections (COVID-19) in professional orchestra musicians and choir singers |
Coronavirus disease 19 infection, Influenza virus infection, Upper respiratory tract infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Charite Universitaetsmedizin Berlin |
|
Germany |
2020-10-02 |
|
DRKS00023385, EA1/237/20, ProMusik |
Phase Not Applicable |
Recruiting |
10 |
|
2500 |
Anne Berghöfer |
2020-11-11 |
| Evaluation of the effectiveness of TAC cocktail in critically ill patients with COVID-19-induced pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
Variable regimens including ascorbic acid (Darou Pakhsh Co) , methylprednisolone (Pfizer) , thiamine (Darou Pakhsh Co) |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tehran University of Medical Sciences |
|
Iran |
2020-04-04 |
|
IR.TUMS.VCR.REC.1399.070, IRCT20200415047080N2 |
Phase 2/Phase 3 Clinical |
No longer recruiting |
1 |
|
30 |
Mohammad ali Sahraian, Rasol Aliannejad, Rasoul Aliannejad |
2020-11-10 |
| COVID-19 With Convalescent Plasma |
Coronavirus disease 19 infection |
convalescent plasma therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Southeast University |
|
China |
2020-01-01 |
2020-11-01 |
COVID-19 CONVALESCENT PLASMA, NCT04616976 |
Phase Not Applicable |
Completed |
1 |
10 Months |
78 |
Chun Pan |
2020-11-10 |
| A clinical trial of NanoAgCide hand sanitizer on Coronavirus patients |
Coronavirus disease 19 infection |
colloidal silver (NanoAgCide) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
WeInnovate Biosolutions Pvt Ltd |
|
India |
2020-10-31 |
|
CTRI/2020/10/028688 |
Phase 2 Clinical |
Recruiting |
1 |
|
20 |
Dr Ramshyam C Agarwal, Prasad Bhagat, Subham Dutta |
2020-11-10 |
| SAFE KiDS Studie: Rapidly applicable surveillance process for COVID-19 in day care centers with dual swabs |
Coronavirus disease 19 infection |
RT-PCR alone |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Johann Wolfgang Goethe-Universitat Frankfurt am Main |
Hessian Ministry for Social Affairs and Integration, Roche Holding AG |
Germany |
2020-06-18 |
2020-09-10 |
20-724, DRKS00023500, SAFE KiDS Studie |
Phase Not Applicable |
Completed |
1 |
2 Months |
1250 |
Sandra Ciesek |
2020-11-11 |
| Effect of dexamethasone or ibuprofen-acetaminophen combination for pain management in symptomatic apical periodontitis during COVID-19 outbreak: a retrospective cohort study |
Coronavirus disease 19 infection, Pain |
dexamethasone alone, acetaminophen plus ibuprofen |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Istanbul Medeniyet University |
|
|
2020-10-04 |
|
TCTR20201027002 |
Phase Not Applicable |
Not yet recruiting |
0 |
|
50 |
Hakan Arslan |
2020-11-10 |
| SILVAR: Siltuximab in Viral ARds (SILVAR) Study |
Coronavirus disease 19 infection, Respiratory distress syndrome |
siltuximab alone, standard-of-care alone |
Heat shock protein inhibitor, IL-6 receptor antagonist |
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
EUSA Pharma |
Syneos Health Inc |
US |
2020-11-02 |
2022-06-30 |
EUSA SYL 0004, NCT04616586, SILVAR |
Phase 3 Clinical |
Not yet recruiting |
1 |
19 Months |
555 |
Melahat Samali, Nancy E Zeleniak, Tina Karunaratne, Zainab Shahid, MD, Ph.D, Zainab Shahid, MD, PhD |
2020-11-11 |
| Study of the Commercial Scale SARS-CoV-2 Vaccine Against the Pilot Scale Among Adults, and Bridging Study of the Immunogenicity in Elderly Against That in Adults |
Coronavirus disease 19 infection |
CoronaVac alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sinovac Research & Development Co Ltd |
|
China |
2020-10-31 |
2021-05-31 |
NCT04617483, PRO-NCOV-3001 |
Phase 3 Clinical |
Recruiting |
1 |
7 Months |
1040 |
Hengkui Zhi, Master, Hongxing Pan, Master |
2020-11-09 |
| KOVID: Impact of the COVID-19 Epidemic on the Hospital Journey of Patients With Cancer of the Digestive System |
Anal tumor, Biliary cancer, Colon tumor, Coronavirus disease 19 infection, Esophagus tumor, Gallbladder tumor, Gastrointestinal tumor, Liver tumor, Pancreas tumor, Rectal tumor, Small intestine cancer, Stomach tumor |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Groupe Hospitalier Paris Saint-Joseph |
|
France |
2020-12-01 |
2021-12-31 |
KOVID, KOVID, NCT04616950 |
Phase Not Applicable |
Not yet recruiting |
1 |
13 Months |
800 |
Anne BURONFOSSE, MD, Helene BEAUSSIER, PharmD, pHD |
2020-11-11 |
| A Clinical Study of Online Active Play Program With Adolescents |
Anxiety disorder, Coronavirus disease 19 infection, Depression |
Revival Active Program alone |
|
Children (6-12 yrs), Adolescents (13-17 yrs) |
Revival Active |
Aarogyam UK |
UK |
2020-03-30 |
2020-07-28 |
NCT04618341, RAP/003 |
Phase Not Applicable |
Completed |
1 |
3 Months |
32 |
Nagamani Krishnamurthy, Rakesh Patel, Tejal Patel |
2020-11-17 |
| Home-based Exercise in COVID-19 Survivors |
Coronavirus disease 19 infection |
telemonitored home-based exercise training program alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
University of Sao Paulo |
|
Brazil |
2020-09-26 |
2021-12-21 |
4.342.082, NCT04615052 |
Phase Not Applicable |
Recruiting |
1 |
14 Months |
60 |
Bruno Gualano, Bruno Gualano, PhD, Bruno Gualano, Phd |
2020-11-09 |
| Effect of Solution-Focused Support Program on Anxiety Levels of Parents During the COVID-19 Pandemic |
Anxiety disorder, Coronavirus disease 19 infection |
Solution-Focused Support Program alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Adiyaman University Research Hospital |
|
Turkey |
2020-07-01 |
2020-12-30 |
2020/751, NCT04609722 |
Phase Not Applicable |
Recruiting |
1 |
5 Months |
60 |
Ceyda Başoğul, Ceyda Başoğul, PhD, Emriye Hilal Yayan, Mürşide .zengin, Mürşide Zengin |
2020-11-09 |
| Heart Up!: Reducing Hopelessness Through Improved Physical Activity in Adults With Heart Disease: With COVID-19 Considerations |
Coronavirus disease 19 infection, Ischemic heart disease, Myocardial infarction, Unstable angina |
Motivational social support from nurse alone, Motivational social support from nurse with additional support from significant other alone, mHealth intervention alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Illinois |
National Institute of Nursing Research |
US |
2019-08-01 |
2023-05-31 |
2018-1485, 3R01NR017649-04S1, Heart Up!, NCT03907891, R01NR017649 |
Phase Not Applicable |
Recruiting |
1 |
46 Months |
225 |
Denise K Busman, MSN, Stacie Vanoosterhout, MS, Susan L Dunn, PhD |
2020-11-11 |
| Online MBI for Families Affected by PPDA |
Anxiety disorder, Coronavirus disease 19 infection, Depression |
mindfulness-based cognitive therapy alone, mindfulness-based stress reduction program alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Children's & Women's Health Centre of British Columbia (C&W) |
|
Canada |
2020-10-20 |
2022-08-31 |
H20-01884, NCT04617132 |
Phase Not Applicable |
No longer recruiting |
1 |
22 Months |
40 |
Katarina Tabi, S. Evelyn Stewart |
2020-11-10 |
| Nasal Photodisinfection COVID Proof of Concept Study |
Coronavirus disease 19 infection |
Steriwave nasal decolonization system (Ondine Biomedical, BC) alone, methylene blue alone, red-light exposure based photodisinfection alone |
|
|
Sunnybrook Health Sciences Centre |
|
Canada |
2020-07-10 |
2021-05-31 |
NCT04615936, NasalPDF001 |
Phase 2 Clinical |
Recruiting |
1 |
10 Months |
100 |
Cari Whyne, PhD, Jeremie Larouche, MD, MSc, Ravi Tuazon, BSc |
2020-11-09 |
| Effect of Respiratory Versus Aerobic Training on Respiratory and Immunity Efficiency in Recovered COVID-19 Patients |
Coronavirus disease 19 infection |
diaphragmatic breathing training alone, endurance training alone, incentive spirometer alone, intermittent exercise alone, medical drug treatment alone, segmental breathing training alone, treadmill walking alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Cairo University |
|
Egypt |
2020-07-02 |
2021-01-20 |
MAHA2020, NCT04613050 |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
80 |
Heba Ahmed Ali Abdeen, Maii Fekry Foad, MD |
2020-11-10 |
| Management of appendicitis during the covid-19 pandemic (observational) |
Appendicitis, Coronavirus disease 19 infection |
Hyperspace Epic 2014 Version IU1, Epic Systems Corporation alone, Laparoscopic appendicectomy alone, Open appendicectomy alone |
|
Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cambridge University Hospitals NHS Foundation Trust |
Addenbrookes NHS Trust, Nuffield Health Bournemouth, University of Rochester Medical Center |
UK |
2019-11-01 |
2020-10-06 |
NCT04615728, PRN8996 |
Phase Not Applicable |
Completed |
1 |
11 Months |
207 |
Mr Ramez Antakia, Mr |
2020-11-10 |
| Prevalence of Thrombosis in COVID-Patients |
Coronavirus disease 19 infection, Thrombosis |
Duplex ultrasound alone, blood test alone, cognitive test alone, smelling test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Klinikum Augsburg |
|
Germany |
2020-11-04 |
2021-06-30 |
COVID THROMBOSE, NCT04615026 |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
400 |
Alexander Hyhlik-Duerr, MD, Yvonne Gosslau, MD |
2020-11-09 |
| SUMMIT: Scaling Up Maternal Mental Health Care by Increasing Access to Treatment |
Anxiety disorder, Coronavirus disease 19 infection, Depression |
TelePsychiatry Program alone, manualized behavioral activation treatment alone |
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Mount Sinai Hospital |
Harvard Medical School, NorthShore University HealthSystem (NorthShore), Patient Centered Outcome Research Institute, St Michaels Hospital, Sunnybrook Health Sciences Centre, University of Colorado, Boulder, University of North Carolina, Women's College Hospital |
Canada, US |
2020-01-06 |
2025-12-30 |
NCT04153864, PCS-2018C1-10621, SUMMIT |
Phase Not Applicable |
Recruiting |
5 |
71 Months |
1368 |
Anastasia Harris, Cindy-Lee Dennis, Daisy R Singla, PhD, Holly Krohn, Maria Michalowska, Richard K Silver, MD, Samantha Meltzer-Brody, MD, MPH, Simone Vigod |
2020-11-09 |
| An observational, retrospective, single-center study to determine the efficacy and safety of tocilizumab in patients with severe COVID-19 infection |
Coronavirus disease 19 infection |
tocilizumab alone |
|
|
Albert Einstein Healthcare Network |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
66 |
|
2020-11-06 |
| ENSEMBLE 2: A Study of Ad26.COV2-S for the Prevention of SARS-CoV-2-mediated COVID-19 in Adults |
Coronavirus disease 19 infection |
JNJ-78436735 alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Janssen Vaccines & Prevention BV |
Janssen Pharmaceuticals Inc |
France, South Africa, Philippines, Colombia, US, UK, Belgium, Germany, Spain |
2020-11-06 |
2023-05-11 |
2020-003643-29, CPMS 46804, CR108916, ENSEMBLE 2, IRAS 288552, ISRCTN14722499, NCT04614948, VAC31518COV3009 |
Phase 3 Clinical |
Recruiting |
106 |
30 Months |
30000 |
Janssen Vaccines & Prevention B.V. Clinical Trial, Mr Malcolm Macartney, Ms Shola Ayeni, Study Contact |
2020-11-16 |
| FX-COVID: FX-06 to Rescue Acute Respiratory Distress Syndrome During Covid-19 Pneumonia |
Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia |
FX-06 alone |
Cadherin-5 modulator, Factor Ia modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assistance Publique Hopitaux de Paris |
|
France |
2020-11-30 |
2021-07-31 |
2020-002056-20, APHP200495, FX-COVID, NCT04618042 |
Phase 2 Clinical |
Not yet recruiting |
1 |
8 Months |
50 |
BRECHOT Nicolas, MD, David HAJAGE, MD, Nicolas BRECHOT, MD |
2020-11-09 |
| An observational study to evaluate the correlation between complement activation and disease severity in patients hospitalized with COVID-19 |
Coronavirus disease 19 infection |
|
|
|
Apellis Pharmaceuticals Inc |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
41 |
|
2020-11-06 |
| Analysis of the immunological response to coronavirus infection |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted |
The University of Birmingham |
Department of Health and Social Care, Medical Research Council |
UK |
2020-04-01 |
2025-06-05 |
CPMS 46588, IRAS 282164, RG_20-038 COVID-19, ISRCTN63911163 |
Phase Not Applicable |
Recruiting |
4 |
62 Months |
600 |
Dr Rachel Bruton, Prof Paul Moss |
2020-11-09 |
| SEMPATICO: Semaglutide to Reduce Myocardial Injury in Patients With COVID-19 |
Coronavirus disease 19 infection, Heart injury |
semaglutide (subcutaneous, diabetes/obesity/NASH), Novo Nordisk alone, standard of care alone |
Glucagon-like peptide 1 receptor agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The University Health Network |
Canadian Institutes of Health Research, St Michaels Hospital, University of Toronto |
Mexico, UK, Canada, Brazil |
2020-11-30 |
2022-03-31 |
NCT04615871, SEMPATICO, UHNSEMPATICO1 |
Phase 2 Clinical |
Not yet recruiting |
10 |
16 Months |
400 |
Andrei C Sposito, MD, Anil Gupta, MD, Beatriz Villegas, DDS, Carlos Fernando, Cheryl Geen-Smith, Daniela M Rosiles, MD, Eduardo Mateos, MD, Emily McDonald, MD, Gina Dutton, Jorge Escobedo, MD, Juan A Santillan, MD, Julieta Valenzuela, MD, Kim Connelly, MD, Mansoor Husain, MD, Priscilla Griffo, Rodrigo B Esper, MD, Sarah Elsayed, Ticiane Bovi, Vinoda Sharma, MD, Vladimir Dzavik, MD, Vladimír Džavík, MD |
2020-11-09 |
| IMMUNO-COVID19: Hyperimmune Plasma for Patients With COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
hyperimmune plasma alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ospedale Papa Giovanni XXIII |
|
Italy |
2020-07-02 |
2022-07-02 |
IMMUNO-COVID19, IMMUNO-COVID19, NCT04614012 |
Phase Not Applicable |
Recruiting |
1 |
24 Months |
100 |
ANNA FALANGA, Anna Falanga |
2020-11-09 |
| Harnessing Network Science to Personalize Scalable Interventions for Adolescent Depression (TRACK to TREAT Phase II) |
Coronavirus disease 19 infection, Depression |
ecological sampling method app alone, psychoeducation alone, web-based behavioral activation single session intervention alone, web-based growth mindset single session intervention alone |
|
Children (6-12 yrs), Adolescents (13-17 yrs) |
State University of New York at Stony Brook |
|
US |
2020-12-31 |
2024-08-31 |
IRB2019-00382, NCT04607902 |
Phase Not Applicable |
Not yet recruiting |
1 |
44 Months |
216 |
Jessica L Schleider, PhD |
2020-11-09 |
| PanDirect: Self-care Tools and Telephone Coaching for Depression and Anxiety During Pandemics |
Anxiety disorder, Coronavirus disease 19 infection, Depression |
lay telephone coaching alone, self-care tool alone |
|
Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
St. Mary's Research Center |
|
Canada |
2020-10-21 |
2021-05-01 |
NCT04609371, PanDirect, SMHC-20-10 |
Phase Not Applicable |
Not yet recruiting |
1 |
6 Months |
176 |
Mark Yaffe, Study coordinator |
2020-11-10 |
| NEOTHROCOVID: Thromboembolic Risk Screening in Patients With Cancer and COVID-19 |
Cancer, Coronavirus disease 19 infection, Thromboembolism |
computed tomography scan alone, electrocardiography alone, iodine alone, peripheral venous ultrasound alone, transthoracic ultrasound alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Antoine Lacassagne (Nice) |
|
France, Monaco |
2020-08-04 |
2021-09-15 |
2020/20, NCT04616846, NEOTHROCOVID |
Phase Not Applicable |
Recruiting |
6 |
13 Months |
120 |
Benjamin HOCH, MD-PHD, Christophe PERRIN, MD-PHD, Céline CELLIER-COËLLE, Denis DOYEN, MD-PHD, Jérome BARRIERE, MD-PHD, Jérôme DOYEN, MD-PHD, Ophélie CASSUTO, MD-PHD |
2020-11-11 |
| The Effects of Multi-modality Physiotherapy in Delaying or Preventing COVID-19 Patient From Admitting to ICU |
Coronavirus disease 19 infection, Viral pneumonia |
Threshold IMT device alone, conventional physical therapy alone, inspiratory muscle training alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Ministry of Health in Kuwait |
|
Kuwait |
2020-11-01 |
2021-04-06 |
JALGHAITH, NCT04617119 |
Phase Not Applicable |
Not yet recruiting |
1 |
5 Months |
38 |
Abdulaziz Al-Husaini, MSc., DR. JASSIM ALGHAITH, Jassim M Alghaith, PhD. |
2020-11-09 |
| Food: A Three-Arm Study Examining Food Insecurity Interventions |
Breast tumor, Coronavirus disease 19 infection |
home grocery delivery alone, medically-tailored hospital-based food pantry access alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Memorial Sloan-Kettering Cancer Center |
Columbia University, Jacobi Medical Center, Lincoln Medical and Mental Health Center, Montefiore Health System, Queens Cancer Center of Queens Hospital, Roswell Park Comprehensive Cancer Center, St. Barnabas Medical Center, The Brooklyn Hospital Center |
US |
2012-05-08 |
2022-05-31 |
12-099, Food, NCT01603316 |
Phase 2 Clinical |
Recruiting |
7 |
120 Months |
668 |
Caroline Hwang, MD, Francesca Gany, MD, MS, Francesca Gany, MD, PhD, Ilmana Fulger, MD, Jennifer Leng, MD, MPH, Tarek Elrafei, D.O. |
2020-11-10 |
| Compassionate Use of REGN-CoV2 for the Treatment of COVID-19 |
Coronavirus disease 19 infection |
REGN-CoV2 alone |
COVID19 Spike glycoprotein inhibitor |
|
Regeneron Pharmaceuticals Inc |
|
|
|
|
NCT04617535, R10933-10987-COV |
Phase Not Applicable |
Recruiting |
0 |
|
|
|
2020-11-09 |
| MIND-VR: Virtual Reality for COVID-19 Operators' Psychological Support |
Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection |
virtual reality-based protocol alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Fondazione IRCCS Istituto Neurologico Carlo Besta |
University of Milano-Bicocca |
Italy |
2020-11-01 |
2021-11-01 |
MIND-VR, MIND-VR/BESTA, NCT04611399 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
90 |
Eleonora F Orena, PhD, Federica Pallavicini, PhD |
2020-11-10 |
| Evaluation of antibody and cytokine detection in tears of COVID-19 patients |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Postgraduate Institute of Medical Education and Research |
|
India |
2020-11-10 |
|
CTRI/2020/11/028813 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
120 |
Reema Bansal |
2020-11-10 |
| AFFORD COVID: Asthma in Families Facing Out-of-pocket Requirements Due to COVID-19 |
Asthma, Coronavirus disease 19 infection |
AAFA's chat bot insurance navigation alone |
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Harvard Pilgrim Health Care |
Asthma and Allergy Foundation of America, Harvard TH Chan School of Public Health, Patient Centered Outcome Research Institute, University of North Carolina |
US |
2020-11-02 |
2023-01-31 |
AFFORD COVID, IHS-1602-34331, NCT04613739 |
Phase Not Applicable |
Not yet recruiting |
1 |
26 Months |
430 |
Alison Galbraith, MD, MPH, Lauren Cripps, MS |
2020-11-10 |
| Yoga program on COVID-19 patients |
Acute stress disorder, Coronavirus disease 19 infection |
integrated biofeedback based yoga program alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Central Council for Research in Yoga and Naturopathy, Ministry of Ayush |
|
India |
2020-11-04 |
|
CTRI/2020/11/028827 |
Phase Not Applicable |
Not yet recruiting |
6 |
|
86 |
Dr Amit Agarwal, Dr Chhavi Gupta, Dr Deepak KK, Dr Minakshi Dhar, Dr Raghavendra Rao M, Dr Sudheer, Dr Sunitha Mondal |
2020-11-09 |
| CRI:SIS: COVID-19 Responsive Intervention: Systems Improvement Simulations (CRI:SIS) |
Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection |
Simulation intervention alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Yale University |
Agency for Healthcare Research and Quality |
US |
2020-11-15 |
2022-11-15 |
1R01HS028340-01, 2000029372, CRI:SIS, NCT04614844 |
Phase Not Applicable |
Not yet recruiting |
1 |
24 Months |
84 |
Ambrose H Wong, MD, MSEd, Ambrose Wong, MD, MSEd, Leigh Evans, MD, Leigh V. Evans, MD |
2020-11-10 |
| Finding Wellness in the Pandemic |
Acute stress disorder, Alcoholism, Coronavirus disease 19 infection, Drug dependence |
trauma Informed Psychotherapy alone, trauma Informed Yoga alone |
|
Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
The University Of Lethbridge |
|
Canada |
2020-11-01 |
2021-04-30 |
2020-096, NCT04615741 |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
200 |
Cheryl Currie, Cheryl Currie, PhD |
2020-11-11 |
| SeroCovid < 19: A Prospective, COVID-19, Seroconversion Study in a Tertiary Pediatric Patient Cohort |
Coronavirus disease 19 infection |
SARS-CoV-2 serological assessment alone |
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Universitair Ziekenhuis Gent |
Universitaet Gent |
Belgium |
2020-10-29 |
2021-11-01 |
BC-08104, NCT04615000, SeroCovid < 19 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
1000 |
Filomeen Haerynck, MD, PhD, Levi Hoste, MD |
2020-11-10 |
| Understanding Reactions to Emotional Material in the Media During COVID-19 |
Coronavirus disease 19 infection, Psychiatric disorder |
Tetris game alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Uppsala University |
|
Sweden |
2020-10-28 |
2021-01-15 |
2020-03991, NCT04608097 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
66 |
Emily Holmes, Prof, Laura Singh, PhD |
2020-11-10 |
| HLA-G-COVID: HLA-G Immuno-Inhibitor Checkpoint Study in Patients With COVID-19 Infection: Molecular and Cellular Assessment |
Coronavirus disease 19 infection |
cellular assessment alone, molecular assessment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hopital Foch |
|
France |
2020-10-19 |
2021-10-31 |
2020_0082, HLA-G-COVID, NCT04613297 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
120 |
Elisabeth Hulier-Ammar, PhD, Olivier BRUGIERE, PhD |
2020-11-09 |
| PACBACK: Spinal Manipulation and Patient Self-Management for Preventing Acute to Chronic Back Pain |
Coronavirus disease 19 infection, Lower back pain |
Spinal manipulation therapy alone, Supported-self management program alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Minnesota |
Duke University, Oregon Health Sciences University, University of North Texas, University of Pittsburgh, University of Washington |
US |
2018-10-25 |
|
COVID19_IMPACT, CSH-2018-26524, NCT03581123, PACBACK |
Phase 3 Clinical |
Suspended |
3 |
|
1180 |
Gert Bronfort, PhD, DC |
2020-11-09 |
| Role of Physiotherapist in enhancing functional aerobic capacity in pulmonary rehabilitation in Covid-19 Patients |
Coronavirus disease 19 infection, Viral pneumonia |
pulmonary rehabilitation program alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Apollo Hospitals Educational Research Foundation |
Indraprastha Apollo Hospital |
India |
2020-11-07 |
|
CTRI/2020/11/028811 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
50 |
Seema Grover |
2020-11-09 |
| Side effects of drugs used in ICU |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Government Institute of Medical Sciences, Greater Noida |
|
India |
2020-11-13 |
|
CTRI/2020/11/028800 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Dr Nazia Nazir |
2020-11-10 |
| The study of psychological interventions either individually or in groups and comparing its effect in reduction of psychological distress in covid-19 positive patients |
Acute stress disorder, Coronavirus disease 19 infection |
individual psychotherapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
HBTMC and Dr RN Cooper Municipal General Hospital |
|
India |
2020-11-02 |
|
CTRI/2020/11/028799 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
55 |
Dr Deoraj sinha, Dr Tejaswini Miskin |
2020-11-09 |
| TECC-Diabetes: Technology-enabled Collaborative Care for Diabetes Management During COVID-19 |
Acute stress disorder, Coronavirus disease 19 infection, Non-insulin dependent diabetes, Psychiatric disorder |
technology-enabled peer support-led collaborative care program alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre for Addiction and Mental Health |
|
Canada |
2020-11-30 |
2021-03-31 |
104-2020, NCT04607915, TECC-Diabetes |
Phase Not Applicable |
Not yet recruiting |
2 |
4 Months |
30 |
Diana Sherifali, Farooq Naeem, Peter Selby, Rosa Dragonetti |
2020-11-10 |
| Effect of SARS-CoV-2 Equine Antiserum Immunoglobulin (Purified F[ab]2 fragment) in hospitalized COVID-19 patients with moderate disease |
Coronavirus disease 19 infection |
MG-K10 alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Biological E Ltd |
|
India |
2020-11-05 |
|
BECT063/Equine.CoV.Ab-Phase-I/CTP-01Ver: 1.1, CTRI/2020/11/028779 |
Phase 1 Clinical |
Not yet recruiting |
2 |
|
72 |
Dr Chandramani Singh, Dr Kishore TSA, Dr Subhash Thuluva, Dr Venugopal |
2020-11-17 |
| COPREG: Prospective Evaluation of the Predictive Criteria of Severity for Respiratory Infection Due to COVID-19 Virus |
Coronavirus disease 19 infection, Respiratory tract infection |
|
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Universitaire de Toulouse |
|
France |
2020-04-27 |
2020-07-17 |
COPREG, NCT04615676, RC31/20/0141 |
Phase Not Applicable |
Completed |
1 |
2 Months |
4734 |
Charles-Henri HOUZE-CERFON |
2020-11-10 |
| Effect of COVID-19 on physical activity, screen time and emotional wellbeing on medical students |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Sawai ManSingh Medical College |
|
India |
2020-11-02 |
|
CTRI/2020/10/028744 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
200 |
Dr Anuradha Yadav |
2020-11-10 |
| HiFlo-COVID: High-Flow Nasal Cannula in Severe COVID-19 With Acute Hypoxemic Respiratory Failure |
Coronavirus disease 19 infection, Hypoxia, Respiratory failure |
High flow nnasal cannula oxygen therapy alone, High-flow nasal cannula alone, oxygen alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fundacion Clinica Valle del Lili |
|
Colombia |
2020-08-11 |
2021-07-28 |
001635, HiFlo-COVID, NCT04609462 |
Phase 2 Clinical |
Recruiting |
1 |
11 Months |
196 |
Gustavo A. Ospina Tascón, MDPhD, Sergio I. Prada, MPA PhD |
2020-11-09 |
| A phase III trial to evaluate the efficacy of recombinant new coronavirus vaccine (CHO cell) for the prevention of SARS-CoV-2 infection |
Coronavirus disease 19 infection |
SARS-CoV-2 protein subunit vaccine (COVID-19), Chongqing Zhifei Biological Products/ Institute of Microbiology, Chinese Academy of Sciences alone |
COVID19 Spike glycoprotein modulator |
|
Chongqing Zhifei Biological Products Co Ltd, Institute of Microbiology, CAS |
|
|
|
|
|
Phase 3 Clinical |
Planned |
0 |
|
|
|
2020-11-06 |
| Application of an intelligent mobile isolation operating cabin preventing COVID-19 infection |
Coronavirus disease 19 infection |
coronary angiography alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Beijing Tsinghua Chang Gung Hospital |
Tsinghua University |
China |
2020-11-30 |
2021-11-29 |
ChiCTR2000039640 |
Phase 0 Clinical |
Recruiting |
1 |
12 Months |
10 |
Boda Zhou, Ping Zhang |
2020-11-10 |
| A Medical Records Based Study for noninvasive ventilation in patients with coronavirus disease 2019 (COVID-19) related acute hypoxemic respiratory failure |
Coronavirus disease 19 infection, Hypoxia, Respiratory failure |
|
|
|
Shenzhen People's Hospital |
|
China |
2020-10-19 |
2020-11-13 |
ChiCTR2000039567 |
Phase Not Applicable |
Recruiting |
1 |
|
40 |
Rongchang Chen, Yingyun Fu |
2020-11-09 |
| A study to evaluate the clinical effect of arbidol combined with adjuvant therapy in patients with COVID-19 |
Coronavirus disease 19 infection |
adjuvant therapy alone, arbidol alone |
|
|
Jiaxing University |
|
China |
|
|
|
Phase 2 Clinical |
Status not specified |
1 |
|
62 |
|
2020-11-06 |
| LKPCOVID19: Level of Knowledge and Preparedness for COVID-19 Pandemic Among Government Dental Officers in Perak, Malaysia: A Cross Sectional Study |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted |
Taiping Hospital |
|
Malaysia |
2020-11-18 |
2020-12-18 |
HSR2020-01 56920, LKPCOVID19, NMRR-20-2367-56920 |
Phase Not Applicable |
Not yet recruiting |
1 |
1 Month |
509 |
Dr FATIN ASHIKIN BINTI ABDUL MUTALIB |
2020-11-10 |
| DETECT: A clinical study to assess the use of wearable fitness devices for the early identification of COVID infection |
Coronavirus disease 19 infection |
Fitbit alone, wearable fitness device alone |
|
|
Scripps Research Institute |
|
US |
2020-03-25 |
|
DETECT |
Phase Not Applicable |
Recruiting |
1 |
|
100000 |
Jennifer Radin, PhD |
2020-11-06 |
| RaDiCo: PCR and Rapid Diagnostic Test on Saliva and Nasopharyngeal Swabs for the Detection of SARS-CoV-2 (COVID-19) |
Coronavirus disease 19 infection |
AAZ-LMB (COVID-VIRO) alone, Panbio COVID-19 Ag (Abbott) alone, Standard Q COVID-19 (Roche) alone, polymerase chain reaction alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Lausanne |
Centre Hospitalier Universitaire Vaudois |
Switzerland |
2020-09-25 |
2020-12-31 |
2020-02269, NCT04613310, RaDiCo |
Phase Not Applicable |
Recruiting |
1 |
3 Months |
1250 |
Blaise Genton, MD PhD, Blaise Genton, MD, PhD, MPH, Blaise Genton, MD-PhD, Gilbert Greub, MD, PhD, Valerie D'Acremont, MD-PhD, Valérie D'Acremont, MD PhD |
2020-11-14 |
| An academic trial to study the prophylactic activity of Vishasura Kudineer (VSK) in healthcare workers exposed/non-exposed to COVID-19 patients |
Coronavirus disease 19 infection |
VSK decoction alone, Vishasura Kudineer (VSK), a Siddha formulation alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Ministry of Ayush |
|
India |
2020-11-12 |
|
CTRI/2020/11/028905 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
|
120 |
Dr K Prasanna Purna, Dr Sivakumar Vijayaraghavalu |
2020-11-10 |
| Telephonic intervention for people tested positive for Covid |
Coronavirus disease 19 infection |
tele counselling alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Yenepoya medical college hospital |
|
India |
2020-11-09 |
|
CTRI/2020/11/028903 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
|
Jeyaram |
2020-11-10 |
| COFIT-20: Exercise via videoconferencing for people with severe mental illness during covid-19 times, a feasibility study |
Coronavirus disease 19 infection, Psychiatric disorder |
Exercise alone, videoconferencing alone |
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Universitair Medisch Centrum Utrecht |
The Netherlands Organisation for Health Research and Development |
Netherlands |
2020-06-09 |
2021-01-31 |
20-313/C, COFIT-20, NL9007 |
Phase Not Applicable |
Recruiting |
1 |
7 Months |
70 |
Lisanne Koomen |
2020-11-12 |
| Seroprevalence Study Johor |
Coronavirus disease 19 infection |
|
|
|
Jabatan Kesihatan Negeri Johar |
|
Malaysia |
2020-11-15 |
2021-01-15 |
57086, NMRR-20-2365-57086 |
Phase Not Applicable |
Status not specified |
1 |
2 Months |
|
Dr Jeyanthini a/p Sathasivam |
2020-11-11 |
| Radiological Perspective of COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
CXR alone, chest CT alone |
|
|
University of Malaya |
|
Malaysia |
2020-11-04 |
2021-08-09 |
57031, NMRR-20-2362-57031 |
Phase Not Applicable |
Recruiting |
1 |
9 Months |
1000 |
Dr nadia fareeda binti muhammad gowdh, Prof Dr KARTINI BINTI RAHMAT |
2020-11-11 |
| PBPCDMSTKKDK: Covid-19 False News Spread on Social Media: a Review of the Community in Kelantan |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted |
Jabatan Kesihatan Negeri Kelantan |
|
Malaysia |
2020-11-15 |
2020-12-31 |
56117, NMRR-20-2355-56117, PBPCDMSTKKDK |
Phase Not Applicable |
Status not specified |
1 |
1 Month |
|
Mr MOHD AZUAN BIN MUSTAPA |
2020-11-12 |
| KAPMASKCOVID-19: Assessment On The Use of Face Mask Among Health Care Workers In Health Clinic During COVID-19 Pandemic in Kelantan |
Coronavirus disease 19 infection |
Face Mask alone |
|
Healthy volunteers accepted |
Jabatan Kesihatan Negeri Kelantan |
|
Malaysia |
2020-11-02 |
2020-12-31 |
56192, KAPMASKCOVID-19, NMRR-20-2346-56192 |
Phase Not Applicable |
Recruiting |
1 |
1 Month |
|
Dr Izyan Auni Binti Mohamad, Dr NORAN BINTI HASHIM |
2020-11-12 |
| To Evaluate the Efficacy and Safety of ANT-V Syrup to Show Antiviral Action of Upper Respiratory Tract Like Common Cold and Act as an Immune Booster to Fight Against Infection, Flu, Fever, Sore Throat, Nasal and Chest Congestion Breathlessness in COVID-19 Patients |
Common cold, Coronavirus disease 19 infection, Upper respiratory tract infection |
ANT-V syrup alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Bhargava Phytolab Limited |
|
India |
2020-11-16 |
|
CTRI/2020/11/028897 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
60 |
Dr Rahul Singh, Pragya Singh |
2020-11-11 |
| COVID-19MASK: The Malaysian experience: Compulsory use of masks and preventive measures during COVID-19 |
Coronavirus disease 19 infection |
masks alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Selayang Hospital |
|
Malaysia |
2020-10-30 |
2020-12-31 |
56946, COVID-19MASK, NMRR-20-2328-56946 |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
|
Dr NORLIZA MAT ARIFFIN |
2020-11-12 |
| Frailty Assessment for COVID-19 Severity |
Aging, Coronavirus disease 19 infection |
|
|
Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
All India Institute of Medical Sciences |
|
India |
2020-11-09 |
|
CTRI/2020/11/028885 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Yudhyavir Singh |
2020-11-06 |
| Cancer Services during COVID-19 Pandemic – Importance of a Symptoms Based Screening Strategy |
Cancer, Coronavirus disease 19 infection |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
All India Institute of Medical Sciences |
|
India |
2020-11-11 |
|
CTRI/2020/11/028859 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
400 |
Akash Kumar |
2020-11-06 |
| Lifestyle and psychological Changes During COVID 19 Lockdown Among Undergraduate Students in Chennai |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs) |
Sri Ramachandra Institute of Higher Education and Research |
|
India |
2020-11-16 |
|
CTRI/2020/11/028848 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
526 |
Dr Akila GV |
2020-11-06 |
| A study on knowledge, attitude and behavior of healthcare workers on practices required to prevent COVID - 19 |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Shree Krishna Hospital, pramukhswami medical college |
|
India |
2020-11-11 |
|
CTRI/2020/11/028846 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
200 |
Chirag Modi |
2020-11-06 |
| Outcomes of Nutrition scores on serious COVID patients |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Vardhman Mahavir Medical College & Safdarjung Hospital |
|
India |
2020-11-09 |
|
CTRI/2020/11/028843 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
78 |
Saurav Mitra Mustafi, Saurav Mitra mustafi |
2020-11-06 |
| ERT-P: Emotion Regulation Training Via Telehealth During the COVID-19 Pandemic |
Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression |
emotion regulation training alone, internet-based online platform alone, videoconferencing software alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Teachers College, Columbia University |
University of Michigan |
US |
2020-05-01 |
2023-01-31 |
20-269, ERT-P, NCT04615416 |
Phase Not Applicable |
Recruiting |
1 |
33 Months |
100 |
Douglas S Mennin, Ph.D., Douglas S Mennin, PhD |
2020-11-06 |
| Correlating the Clinical and CT Severity of COVID-19 Patients with the Inflammatory Markers and Co-morbidities |
Coronavirus disease 19 infection |
CB-NAAT alone, CT Thorax alone, GeneXpert alone, RT-PCR alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sri Ramachandra University |
Sri Ramachandra Institute of Higher Education and Research |
India |
2020-11-15 |
|
CTRI/2020/11/028836 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
200 |
Aparna Ganesh, Preetam Arthur |
2020-11-06 |
| Clinical evaluation of STANDARD Q COVID-19 Ag Test |
Coronavirus disease 19 infection |
STANDARD Q COVID-19 Ag test alone |
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
SD Biosensor Inc |
|
India |
2020-10-30 |
|
CTRI/2020/10/028774 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
500 |
Dr Niraj Kothari |
2020-11-09 |
| HCBASE: Efficay of two hydroxychloroquine based drug combination regimens in comparison to standard of care in The Treatment of Hospitalized COVID-19 Patients |
Coronavirus disease 19 infection |
Variable regimens including azithromycin , hydroxychloroquine , lopinavir + ritonavir , zinc sulphate |
HIV protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Institute for Pharmaceutical Research and Developments, Federal Republic of Nigeria |
University of Abuja |
Nigeria |
2020-08-27 |
2021-03-01 |
HCBASE, PACTR202010519682638 |
Phase 2 Clinical |
Not yet recruiting |
1 |
6 Months |
210 |
Margaret Ekpenyong, Olobayo Kunle, Vivian Kwaghe |
2020-11-11 |
| Screening for COVID-19 |
Coronavirus disease 19 infection |
breath acoustic analysis alone, breathing sounds analysis algorithm alone, iPhone app (ID Fusion Software, Inc) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Manitoba |
Function Four Ltd, ID Fusion Software Inc, Natural Sciences and Engineering Research Council of Canada |
Canada |
2020-11-15 |
2021-12-30 |
B2020:070 (HS24165), NCT04615208 |
Phase Not Applicable |
Not yet recruiting |
1 |
13 Months |
200 |
Mari Garcia, M.Sc., Zahra Moussavi, Ph.D. |
2020-11-15 |
| An observational study on the levels of IL-6 early after tocilizumab to distinguish survivors from non-survivors in COVID-19 pneumonia |
Coronavirus disease 19 infection, Pneumonia |
tocilizumab alone |
|
|
Azienda Ospedaliero-Universitaria di Udine |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
24 |
|
2020-11-05 |
| FVR: Efficacy and Safety of Favipiravir in Covid-19 Patients in Indonesia |
Coronavirus disease 19 infection |
Standard of care alone, azithromycin plus favipiravir |
RNA polymerase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
INA-RESPOND Secretariat |
National Institute Of Health Research & Development (Nihrd)- Ministry Of Health Of The Republic Of Indonesia |
Indonesia |
2020-10-15 |
2020-12-31 |
FVR, FVR, NCT04613271 |
Phase 3 Clinical |
Recruiting |
3 |
2 Months |
210 |
Dr Harli Amir Mahmudji, Dr Harli Amir Mahmudji, SpPD KEMD, Dr. dr. Armedy Ronny Hasugiana, M. Biomed, MD, dr. Adria Rusli, Sp.P, dr.Sofyan Budi Raharjo, SpP FISR |
2020-11-06 |
| Ketogenic Diet as Protective Factor During COVID-19 |
Coronavirus disease 19 infection |
ketogenic diet with phytoextract alone, low carbohydrate diet alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Padova |
San Bortolo Hosp |
Italy |
2020-11-01 |
2021-08-30 |
KDSARS0120, NCT04615975 |
Phase Not Applicable |
Recruiting |
1 |
9 Months |
28 |
Antonio Paoli, MD, Lorenzo Cenci, MD |
2020-11-09 |
| E-COCCON: Effect of COVID-19-related Containment in Children |
Coronavirus disease 19 infection, Post traumatic stress disorder |
|
|
Children (6-12 yrs), Adolescents (13-17 yrs) |
Centre Hospitalier Universitaire de Toulouse |
|
France |
2020-06-10 |
2020-11-30 |
E-COCCON, NCT04615195, RC31/20/0205 |
Phase Not Applicable |
Recruiting |
1 |
5 Months |
1000 |
AURIOL Françoise, PhD, CLAUDET Isabelle, Pr, Françoise Auriol, PhD, Isabelle CLAUDER, Pr, Isabelle CLAUDET, Pr |
2020-11-06 |
| IVIG in Patients With Severe COVID-19 Requiring Mechanical Ventilation |
Coronavirus disease 19 infection |
Octagam alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sharp HealthCare |
|
US |
2020-11-01 |
2021-06-30 |
2010902, COVID-IVIG VENT, NCT04616001 |
Phase 4 Clinical |
Not yet recruiting |
1 |
8 Months |
10 |
George Sakoulas, MD, Kathryn Miller, Matthew Geriak, PharmD |
2020-11-09 |
| Squalene and COVID-19 |
Coronavirus disease 19 infection |
Variable regimens including chloroquine phosphate , hydroxychloroquine , lopinavir + ritonavir , microemulsion containing extracted squalene , ribavirin |
HIV protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Mashhad University of Medical Sciences |
|
Iran |
2020-10-31 |
|
IR.MUMS.REC.1399.468, IRCT20200927048848N2 |
Phase 3 Clinical |
Recruiting |
1 |
|
15 |
Deputy of Research and Technology, Mahmood Ebrahimi |
2020-11-10 |
| A proof of concept, investigator-initiated trial was to study efficacy of TD-213 in treating patients with confirmed mild to moderate COVD-19 infections |
Coronavirus disease 19 infection |
TD-213 alone |
|
|
TrippBio Inc |
|
US |
|
|
|
Phase Not Applicable |
No longer recruiting |
1 |
|
|
Dr. Moti N. Ramgopal |
2020-11-16 |
| Recovery Profiles in Patients With SARS-CoV-2 Outcomes Undergoing Rehabilitation |
Coronavirus disease 19 infection, Psychiatric disorder |
comprehensive intensive rehabilitation alone, early rehabilitation alone, home mindfulness training alone, personalized ambulatory walking exercise alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Azienda Ospedaliero-Universitaria di Ferrara |
|
Italy |
2020-03-30 |
2021-06-03 |
COVID19_REHABILITATION, NCT04615390 |
Phase Not Applicable |
Recruiting |
1 |
14 Months |
200 |
Alessandra Botti, MD, Anna Scotti, MD, Antonella Occhi, PT, Dino De Filippo, MD, Elisabetta Antiga, MD, Fabio Manfredini, MD, PhD, Francesca Filippini, PT, Francesco Baldasso, MD, Giada Milani, PsyD, PhD student, Giulia Bellon, MD, Giulia Dallagà, PsyD, Ilaria Ferioli, PT, Nicola Lamberti, PhD, Silvia Mottaran, PT, Sofia Straudi, Sofia Straudi, MD, PhD, Susanna Lavezzi, MD |
2020-11-10 |
| A phase III clinical trial of MP-0420 for the potential treatment of COVID-19 infection |
Coronavirus disease 19 infection |
MP-0420 alone |
Angiotensin converting enzyme 2 inhibitor, COVID19 Spike glycoprotein inhibitor |
|
Molecular Partners AG |
Novartis AG |
|
|
|
|
Phase 3 Clinical |
Planned |
0 |
|
|
|
2020-11-05 |
| A phase II clinical trial of MP-0420 for the potential treatment of COVID-19 infection |
Coronavirus disease 19 infection |
MP-0420 alone |
Angiotensin converting enzyme 2 inhibitor, COVID19 Spike glycoprotein inhibitor |
|
Molecular Partners AG |
Novartis AG |
|
|
|
|
Phase 2 Clinical |
Planned |
0 |
|
|
|
2020-11-05 |
| HFP: Home Fitness Project |
Coronavirus disease 19 infection |
exercise program alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Kyoto University |
|
Japan |
2020-10-30 |
|
HFP, UMIN000042340 |
Phase Not Applicable |
Recruiting |
1 |
|
100 |
Norio Watanabe, Takashi Ishida |
2020-11-06 |
| Effect of Iranian Borage on the management of Covid-19 symptoms |
Coronavirus disease 19 infection |
Iranian borage aerial part alone, routine treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shiraz University of Medical Sciences |
|
Iran |
2020-11-07 |
|
IR.SUMS.REC.1399.015, IRCT20201016049048N1 |
Phase 0 Clinical |
Recruiting |
1 |
|
60 |
Ali Sahragard, Dr. Abbas Rezaeian zadeh, Mohammad Mehdi Zarshenas, Mohammad mehdi Zarshenas |
2020-11-09 |
| A phase II, randomized, open-label, two-arm study of silmitasertib versus standard of care or supportive care in the treatment of patients with moderately ill COVID-19 penumonia infection |
Coronavirus disease 19 infection, Viral pneumonia |
silmitasertib alone |
Casein kinase II inhibitor |
|
Senhwa Biosciences Inc |
|
US, Georgia |
|
|
|
Phase 2 Clinical |
Not yet recruiting |
2 |
|
20 |
Dr Christopher P Recknor |
2020-11-16 |
| CardiolRx in Patients With COVID-19 and Cardiovascular Disease or Risk Factors |
Cardiovascular disease, Cerebrovascular disease, Coronavirus disease 19 infection, Diabetes mellitus, Hypertension, Obesity, Peripheral vascular disease |
cannabidiol (nanoformulation/subcutaneous, heart failure), Cardiol Therapeutics alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cardiol Therapeutics Inc |
|
US |
2020-12-31 |
2021-09-30 |
CARDIOL 100-03, NCT04615949 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
9 Months |
422 |
Andrea B Parker, PhD, Dennis McNamara, MD, Dr. Arvind Bhimaraj, Dr. Barry Trachtenberg, Dr. Carsten Tschöpe, Dr. Leslie Cooper, Dr. Matthias Friedrich, Dr. Peter Liu, Dr. Wilson Tang, Eldon R Smith, MD |
2020-11-06 |
| VOC-COVID-Diag: Analysis of Volatile Organic Compounds in Exhaled Air and in Sweat in the Context of Suspicion of COVID-19 Infection |
Coronavirus disease 19 infection |
canine odor detection alone, electronic nose alone, mass spectrometry alone, volatile organic compound analysis alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hopital Foch |
|
France |
2020-10-21 |
2021-10-31 |
2020_0143, NCT04614883, VOC-COVID-Diag |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
100 |
Elisabeth Hulier-Ammar, PhD, Helene Salvator, MD, Hélène Salvator, MD, Philippe Devillierr, MD PhD |
2020-11-09 |
| HOPE: The digital Hope program for people living with cancer during COVID-19 |
Cancer, Coronavirus disease 19 infection |
HOPE program alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Coventry University |
|
UK |
2020-03-31 |
2020-09-02 |
HOPE, IRRID: RR1-10.2196/24264, ISRCTN79623250 |
Phase Not Applicable |
Completed |
2 |
5 Months |
40 |
Dr Hayley Wright, Prof Turner |
2020-11-06 |
| An observational study to determine tocilizumab treatment for cytokine release syndrome in hospitalized patients with Coronavirus Disease 2019 |
Coronavirus disease 19 infection, Systemic inflammatory response syndrome |
tocilizumab alone |
|
|
Yale University |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
239 |
|
2020-11-06 |
| Cov-Peru: Efficacy, Safety and Immunogenicity of Inactivated SARS-CoV-2 Vaccines (Vero Cell) in Healthy Adult Population In Peru |
Coronavirus disease 19 infection |
COVID-19 vaccine (inactivated, Vero cells/intramuscular), Beijing Biological Products Institute/National Institute for Viral Disease Control and Prevention of Chinese Center for Disease Control and Prevention alone, COVID-19 vaccine (inactivated, Vero cells/intramuscular), Wuhan Institute of Biological Products/Wuhan Institute of Virology, CAS alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universidad Peruana Cayetano Heredia |
Universidad Nacional Mayor de San Marcos |
Peru |
2020-09-10 |
2021-09-01 |
Cov-Peru, NCT04612972, UPERUANACH |
Phase 3 Clinical |
Recruiting |
1 |
11 Months |
6000 |
German Malaga, MD, Hugo García, PhD |
2020-11-09 |
| Lung Function, Exercise Capacity, and Serology Responses in Patients With COVID-19 |
Coronavirus disease 19 infection |
remdesivir alone, Variable regimens including interferon beta-1b , lopinavir + ritonavir , ribavirin |
COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, HIV protease inhibitor, RNA polymerase modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Chinese University of Hong Kong |
Health and Health Services Research Fund, The University of Hong Kong |
Hong Kong |
2020-05-22 |
2022-05-21 |
2020.229, NCT04611243 |
Phase Not Applicable |
Recruiting |
1 |
24 Months |
80 |
David S Hui, MD, Karen Yiu, BSc, Susanna Ng, MBChB, Susanna So-Shan Ng |
2020-11-06 |
| COVID-19: Health-Related Quality of Life of Patients With Asthma During the Pandemic of COVID-19 |
Asthma, Coronavirus disease 19 infection, Lung disease |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Cairo University |
|
Egypt |
2020-05-01 |
2021-03-01 |
COVID-19, NCT04613245, SERIAL 39-2020 |
Phase Not Applicable |
Recruiting |
1 |
10 Months |
400 |
Naglaa Youssef, Youssef |
2020-11-08 |
| Clinical study on the efficacy and safety of Jieyuwan in the treatment of epidemic stress, anxiety and depression (stagnation of liver Qi syndrome) |
Anxiety disorder, Coronavirus disease 19 infection, Depression, Viral pneumonia |
Jieyuwan pill alone, psychological support therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Dongfang Hospital |
Tiansheng Pharmaceutical Group Co Ltd |
China |
2020-11-15 |
2021-10-15 |
ChiCTR2000039536 |
Phase 4 Clinical |
Not yet recruiting |
1 |
11 Months |
390 |
Rongjuan Guo, Tian'ge Lu |
2020-11-10 |
| Evaluation of the Efficacy of Xylitol Nasal Spray Against SARS-CoV-2 |
Coronavirus disease 19 infection |
Variable regimens including Xlear nasal spray |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Larkin Community Hospital |
Ferrer Medical Innovations Llc, Xlear Inc |
US |
2020-08-08 |
2021-08-08 |
LCH-3-082020, NCT04610801 |
Phase 3 Clinical |
Recruiting |
2 |
12 Months |
200 |
CAMILLE GO, Camille Celeste Go, M.D., Camille Go, MD, Gustavo Ferrer, Gustavo Ferrer, M.D, Marcos Sanchez-Gonzalez, Marcos Sanchez-Gonzalez, MD |
2020-11-17 |
| PExCoV: Therapeutic Plasma Exchange as an Adjunctive Strategy to Treat Coagulopathy and Inflammation in Severe Covid-19 |
Blood clotting disorder, Coronavirus disease 19 infection, Inflammatory disease, Respiratory failure |
plasma exchange alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Zurich |
|
|
2020-12-31 |
2021-12-31 |
NCT04613986, PExCoV, SD01 |
Phase Not Applicable |
Not yet recruiting |
0 |
12 Months |
20 |
|
2020-11-07 |
| A phase IIa proof-of-concept study to evaluate safety and initial efficacy of AS-1411 for the treatment of COVID-19 |
Coronavirus disease 19 infection |
AS-1411 alone |
BCL2 gene inhibitor, Nucleolin inhibitor |
|
Qualigen Therapeutics Inc |
|
|
2021-07-31 |
|
|
Phase 2a Clinical |
Planned |
0 |
|
|
|
2020-11-11 |
| COV2020: Medical-biological Research of the Pathogenesis of COVID-19 Disease Caused by SARS-CoV-2 |
Coronavirus disease 19 infection |
PCR testing alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Research Institute for Physico-Chemical Medicine of the Federal Medical-Biological Agency of the Russian Federation |
Burnasyan Federal Medical Biophysical Center, Federal Research Clinical Center of Federal Medical and Biological Agency, Federal State Budgetary Healthcare Institution, Hospital RAS, Federal'noe Gosudarstvennoe Bjudzhetnoe Uchrezhdenie "Nauchnyj Tsentr Problem Zdorov'ja Sem'i I Repr, Moscow city hospital named after S.I. Spasokukotskiy |
Russian Federation |
2020-07-21 |
2022-12-31 |
COV2020, COV2020, NCT04611841 |
Phase Not Applicable |
Recruiting |
1 |
29 Months |
250 |
Vadim Govorun, MD |
2020-11-14 |
| SATICOVID19: Clinical Characteristics and Outcomes of Patients With COVID-19 on Mechanical Ventilation in Argentina |
Coronavirus disease 19 infection |
Mechanical ventilation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Argentina Intensive Care Society |
|
Argentina |
2020-03-20 |
2020-10-31 |
NCT04611269, SATI, SATICOVID19 |
Phase Not Applicable |
Completed |
5 |
7 Months |
950 |
Elisa Estenssoro, MD |
2020-11-17 |
| Randomized, controlled trial to test the (cost)effectiveness of step-by-step, a smartphone-based self-help program for Syrian refugees in Egypt |
Acute stress disorder, Coronavirus disease 19 infection |
Step By Step app alone, information based treatment as usual alone, smartphone and internet-based self-help program alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Berlin Free University |
EU Horizon 2020 |
Egypt |
2020-12-01 |
|
2020-2021-009, DRKS00023505 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
532 |
Sebastian Burchert |
2020-11-08 |
| A Study Looking at the Efficacy, Immune Response, and Safety of a COVID-19 Vaccine in Adults at Risk for SARS-CoV-2 |
Coronavirus disease 19 infection |
NVX-CoV2373 alone |
COVID19 Spike glycoprotein modulator |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Novavax Inc |
US Department of Health and Human Services, US Government |
US, Mexico, Puerto Rico |
2020-11-30 |
2022-12-30 |
2019NCOV-301, NCT04611802 |
Phase 3 Clinical |
Not yet recruiting |
110 |
25 Months |
30000 |
Kristin Ciccarelli, Lisa M Dunkle, MD |
2020-11-17 |
| SeCoBelChild: Sero-prevalence COVID-19 Among Belgian Children |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs) |
Sciensano |
Katholieke Universiteit Leuven, McGill University |
|
2020-11-20 |
2021-08-31 |
NCT04613817, SC_044A, SeCoBelChild |
Phase Not Applicable |
Not yet recruiting |
0 |
9 Months |
1640 |
Els Duysburgh, MD, MPH, PhD, Melissa Vermeulen, MD |
2020-11-05 |
| A clinical trial of IMS-001 for the treatment of COVID-19 and acute respiratory distress syndrome |
Coronavirus disease 19 infection, Respiratory distress syndrome |
IMS-001 alone |
|
|
AgeX Therapeutics Inc, Imstem Biotechnology Inc |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-11-04 |
| Open-label, Multicenter Study to Evaluate the Efficacy of PLX-PAD for the Treatment of COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
PLX stem cell therapy, Pluristem/Cha Bio & Diostech alone, best standard medical care alone |
IL-6 receptor agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Pluristem Ltd, Pluristem Therapeutics Inc |
|
Israel, Germany |
2020-11-30 |
2022-03-31 |
NCT04614025, PLX-COV-03 |
Phase 2a Clinical |
Recruiting |
8 |
16 Months |
40 |
Alona Paz, Dr, Alona Paz, Dr., Asaf Peretz, Dr, Asaf Peretz, Dr., Ayelet Raz-Pasteur, Dr, Ayelet Raz-Pasteur, Dr., Christian Karagiannidis, Prof. Dr, Christian Karagiannidis, Prof. Dr., Christian Putensen, Prof. Dr, Christian Putensen, Prof. Dr., Elias Mazen, Prof, Elias Mazen, Prof., Julia Kovalenko, Dr, Julia Kovalenko, Dr., Ronny Ben-Avi, Dr, Ronny Ben-Avi, Dr. |
2020-11-05 |
| REHSCU: Remimazolam Infusion in the Context of Hypnotic Shortage in the Critical Care Unit During the Pandemic of COVID-19 |
Coronavirus disease 19 infection |
remimazolam alone |
GABA A receptor agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
CHU De Nantes |
PAION UK Ltd |
France |
2020-11-01 |
2021-05-01 |
2020-003689-37, NCT04611425, RC20-0319, REHSCU |
Phase 2 Clinical |
Recruiting |
1 |
6 Months |
30 |
Antoine ROQUILLY, MD, PhD, Bertrand ROZEC, MD, PhD, Direction Recherche et Innovation, Raphaël CINOTTI, MD |
2020-11-12 |
| CoV-PREMOC: Sars-CoV-2 Infection (Covid-19) During Pregnancy: Effects on Mother and Child |
Coronavirus disease 19 infection |
biological sampling alone, magnetic resonance imaging alone, ultrasound alone |
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Klinikum Grosshadern Der Ludwig-Maximilians-Universitat |
|
Germany |
2020-11-06 |
|
20-733, CoV-PREMOC, DRKS00023447, LMU-RAD00530 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
30 |
Sophia Stöcklein, Vanessa Koliogiannis |
2020-11-04 |
| Effects of COVID-19 on levels of stress and anxiety in dental students |
Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Heidelberg |
|
Germany |
2020-11-03 |
|
DRKS00023499, S-627/2020 |
Phase Not Applicable |
Recruiting |
1 |
|
100 |
Andreas Zenthöfer, Anna-Luisa Klotz |
2020-11-04 |
| A prospective, multicentre, observational study to evaluate the feasibility of extracorporeal blood purification (EBP) using the company’s Oxiris filter set in severely ill patients with COVID-19 |
Coronavirus disease 19 infection |
Baxter's Prismaflex system alone, Oxiris filter set alone, extracorporeal blood purification alone |
|
|
Baxter International Inc |
|
Italy |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
37 |
Gianluca Villa |
2020-11-04 |
| Diagnostic Performance of an Antigen Test for SARS-CoV-2 Infection (COVID-19) |
Coronavirus disease 19 infection |
Quidel Sofia SARS Antigen Fluorescent Immunoassay alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Carilion Clinic |
|
US |
2020-11-01 |
2021-01-31 |
EPLING-533, IRB-20-1088, NCT04610489 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
800 |
John W Epling, MD |
2020-11-05 |
| CONTACT: A Study to Assess Infection Rate of Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2) and It's Affect on Quality of Life in Adult Volunteers in Lake County, Illinois |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
AbbVie Inc |
|
US |
2020-10-30 |
2021-09-24 |
CONTACT, H20-308, NCT04611230 |
Phase Not Applicable |
Not yet recruiting |
1 |
10 Months |
1250 |
ABBVIE CALL CENTER, AbbVie Inc. |
2020-11-05 |
| SARS-COV2 Pandemic Serosurvey in a Rare Disease Population |
Coronavirus disease 19 infection, Rare disease |
|
|
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Institute of Allergy and Infectious Diseases |
National Institutes of Health Clinical Center |
US |
2020-11-20 |
2023-04-30 |
000210-I, 10000210, NCT04609085 |
Phase Not Applicable |
Recruiting |
2 |
29 Months |
5000 |
Matthew J Memoli, M.D. |
2020-11-17 |
| Aerosol Transmission of Severe Acute Respiratory Syndrome Coronavirus of Coronavirus Disease 2019 |
Coronavirus disease 19 infection |
Real-time-polymerase-chain reaction alone, cell culture alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hospital Italiano de Buenos Aires |
|
Argentina |
2020-05-08 |
2021-01-01 |
1345, NCT04609774 |
Phase Not Applicable |
No longer recruiting |
1 |
7 Months |
8 |
VANINA LAURA PAGOTTO |
2020-11-05 |
| Endothelial Damage and Angiogenesis Biomarkers During COVID-19 |
Coronavirus disease 19 infection, Vascular disease |
ELISA kit alone, enzyme-linked immunosorbent assay alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Chile |
|
Chile |
2020-11-30 |
2021-11-30 |
NCT04609332, OAIC 1164/20, OAIC/20 |
Phase Not Applicable |
Not yet recruiting |
1 |
12 Months |
40 |
Carlos Romero, M.D., Catalina Valdes, M.D., Felipe Andrés Maldonado Caniulao, Felipe Maldonado, M.D., M.Sc., Mónica Cáceres, Ph.D., Nicolas Valls, M.D., M.Sc., Oscar Cerda, Ph.D. |
2020-11-11 |
| A single-center, retrospective study to assess the effects of hydroxychloroquine on COVID-19 in intensive care unit patients |
Coronavirus disease 19 infection, Viral pneumonia |
hydroxychloroquine alone |
|
|
Aix-Marseille Université, Assistance Publique Hopitaux De Marseille |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
29 |
|
2020-11-06 |
| Lung Diffusing Capacity for Nitric Oxide and Carbon Monoxide Early After Mild-to-severe COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
|
|
European Ancestry |
IRCCS AOU San Martino – IST |
|
Italy |
2020-05-14 |
2020-10-12 |
NCT04610554, SARS-COV-2_DLNO |
Phase Not Applicable |
Completed |
1 |
4 Months |
74 |
Giovanni Barisione, MD |
2020-11-05 |
| Mesenchymal Stem Cells in Patients Diagnosed With COVID-19 |
Coronavirus disease 19 infection, Lung injury, Multiple organ failure, Respiratory insufficiency |
adipose-derived mesenchymal stem cell therapy (iv, COVID-19), Instituto de Terapia Celular alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Instituto De Seguridad Y Servicios Sociales De Los Trabajadores Del Estado |
Instituto de Terapia Celular: ITC |
Mexico |
2020-08-01 |
2020-12-30 |
060I.2020, NCT04611256 |
Phase 1 Clinical |
Recruiting |
1 |
4 Months |
20 |
M. Eunice Rodríguez Arellano, Martha E. Rodríguez Arellano, MD |
2020-11-17 |
| A clinical trial of NeuCovix-HT for the detection of functional antibodies in plasma or serum that neutralize the SARS-CoV-2 (COVID-19) virus |
Coronavirus disease 19 infection |
NeuCovix-HT alone |
|
|
Axim Biotechnologies Inc |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-11-03 |
| Long-term Follow-up in Survivors of Critical Illness |
Cognitive disorder, Coronavirus disease 19 infection, Psychiatric disorder, Respiratory distress syndrome, Viral pneumonia |
|
|
|
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia |
Universita degli Studi di Brescia |
Italy |
2020-06-01 |
2021-07-01 |
NCT04608994, NP2595 |
Phase Not Applicable |
Recruiting |
1 |
13 Months |
160 |
Nicola Latronico, Professor, Piva Simone, Simone Piva |
2020-11-05 |
| Delivery During COVID-19 Pandemic: Implications for Obstetrics, Maternal Psychopathology, and Mother-Infant Relationship |
Coronavirus disease 19 infection, Postnatal depression |
|
|
Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Hillel Yaffe Medical Center |
|
Israel |
2020-06-01 |
2024-06-30 |
0082-20-HYMC, NCT04609501 |
Phase Not Applicable |
No longer recruiting |
1 |
49 Months |
440 |
Rinat Gabbay-Benziv, MD |
2020-11-06 |
| Surfactant Levels in the Lungs of COVID-19 Patients |
Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia |
lung fluid sampling alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Zealand University Hospital |
|
Denmark |
2020-11-01 |
2022-10-01 |
NCT04609488, SJ-859X |
Phase Not Applicable |
Not yet recruiting |
1 |
23 Months |
30 |
Henning B Nielsen, Henning Bay Nielsen |
2020-11-05 |
| Efficacy of Arbidol in treatment of COVID-19 |
Coronavirus disease 19 infection |
Variable regimens including Arbidol (Pharmstandard) , N-acetylcysteine , bromhexine , cetirizine , famotidine , fluticasone propionate , naproxen |
Histamine H1 receptor antagonist, Histamine H2 receptor antagonist |
Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Babol University of Medical Sciences |
|
Iran |
2020-11-15 |
|
IR.MUBABOL.REC.1399.283, IRCT20201024049134N1 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
100 |
Mohammad Barary, Mostafa Javanian, Reza Ghadimi |
2020-11-05 |
| TeleRea'nCo: Follow-up of patients with COVID-19 |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hopitaux Universitaires de Strasbourg |
|
France |
2020-10-27 |
2023-04-27 |
7883, NCT04609839, TELEREA'NCO, TeleRea'nCo |
Phase Not Applicable |
Recruiting |
1 |
30 Months |
200 |
Eric DEMONSANT, Laurence KESSLER, Pr |
2020-11-05 |
| An observational, comparative study to evaluate the time to achieve negative nucleic acid testing and hospital stays between danoprevir and lopinavir/ritonavir in the treatment COVID-19 |
Coronavirus disease 19 infection |
danoprevir alone, lopinavir + ritonavir alone |
HIV protease inhibitor, Hepatitis C virus NS3 protease inhibitor |
|
Nanchang Ninth Hospital |
|
China |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
33 |
|
2020-11-04 |
| Effectiveness of Tissue plasminogen activator (TPA) for treatment of ARDS induced by COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
regular care alone, alteplase plus enoxaparin sodium |
Low molecular weight heparin, Tissue plasminogen activator stimulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Tehran University of Medical Sciences |
|
Iran |
2020-09-22 |
|
IR.TUMS.VCR.REC.1399.025, IRCT20200415047080N1 |
Phase 3 Clinical |
Recruiting |
1 |
|
30 |
Mohhamad Ali Sahraian, Rasoul Aliannejad |
2020-11-05 |
| COVID-VIRO: Diagnostic Performance Evaluation of a Novel SARS-CoV-2 (COVID-19) Antigen Detection Test |
Coronavirus disease 19 infection |
COVID-VIRO novel antigen-based rapid detection test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre Hospitalier Regional D'Orleans |
|
France |
2020-10-13 |
2020-11-13 |
CHRO-2020-18, COVID-VIRO, NCT04609969 |
Phase Not Applicable |
Recruiting |
1 |
1 Month |
200 |
Aurélie DESPUJOLS, Elodie POUGOUE TOUKO, Thierry PRAZUCK, Thierry PRAZUCK, Dr, Thierry PRAZUCK, MD |
2020-11-05 |
| LidoCovid: Impact of Intravenous Lidocaine on Clinical Outcomes of Patients With ARDS During COVID-19 Pandemic |
Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia |
lidocaine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Hopitaux Universitaires de Strasbourg |
|
|
2020-11-04 |
2024-02-04 |
7820, LidoCovid, NCT04609865 |
Phase 3 Clinical |
Not yet recruiting |
0 |
39 Months |
100 |
Thiên-Nga CHAMARAUX-TRAN, MD |
2020-11-06 |
| INSPIRE: Innovative Support for Patients With SARS-COV2 Infections (COVID-19) Registry |
Coronavirus disease 19 infection |
innovative support digital platform alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Rush University Medical Center |
Jefferson Medical College, University of California Los Angeles, University of California San Francisco, University of Texas Health Science Center Houston, University of Texas Southwestern Medical Center, University of Washington, Yale University |
US |
2020-11-14 |
2022-11-14 |
75D30120C08008, INSPIRE, NCT04610515 |
Phase Not Applicable |
Not yet recruiting |
8 |
24 Months |
4800 |
Ahamed Idris, MD, Anna Marie Chang, MD, Annie Lee, PhD, Bala Hota, MD, Doug Bell, MD, PhD, Elizabeth Vidales, Grace Amadio, Graham Nichol, MD, Henry Wang, MD, Jacqueline Brown, Joann Elmore, MD, Katherine Koo, Keith Jerome, MD, Kelli O'Loughlin, MD, Lauren Wisk, PhD, Matthew Thompson, MD, Michael Gottlieb, MD, Michelle Santangelo, Nicole Renzi, Nikki Gentile, MD, Paula Arellano-Cruz, Ralph Wang, MD, Raul Moreno, Robert A Weinstein, MD, Robert Rodriguez, MD, Robin Kemball, Victoria Lyon |
2020-11-06 |
| Evaluation of the efficacy and safety of Doxycycline in combination with standard treatment in Covid-19 patients |
Coronavirus disease 19 infection |
doxycycline alone, standard treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shahid Sadoughi University of Medical Sciences and Health Services |
|
Iran |
2020-09-14 |
|
IR.SSU.MEDICIN E.REC.1399.140, IRCT20191211045691N2 |
Phase 3 Clinical |
No longer recruiting |
1 |
|
60 |
Dr.Masoud Mirzaei, Mohammad Bagher Owlia, Seyed Ruhollah Mousavinasab, Zohreh Akhoundi Meybodi |
2020-11-05 |
| Evaluation of the effect of ghamz with needle on improvement of respiratory symptoms of COVID-19 patients admitted to hospital |
Coronavirus disease 19 infection, Respiratory disease |
conventional medical treatment alone, ghamz massage-acupuncture therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Shiraz University of Medical Sciences |
|
Iran |
2020-04-13 |
2020-07-20 |
IR.SUMS.REC.1399.043, IRCT20150825023753N17 |
Phase 3 Clinical |
Completed |
1 |
3 Months |
18 |
Dr. Amir Mohammad Jaladat, Dr. Mohammad Mahdi Parvizi, Dr. Younes Ghasemi |
2020-11-05 |
| Immune Defence: Evaluating nasal sprays and physical activity/stress management in reducing respiratory infections in primary care |
Coronavirus disease 19 infection, Respiratory tract infection |
Saline nasal spray alone, Vicks First Defence nasal spray alone, physical activity and stress management alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Of Southampton |
National Institute for Health Research (NIHR) |
UK |
2019-09-01 |
2024-10-01 |
56474, IRAS 288431, CPMS 47080, ISRCTN17936080, Immune Defence |
Phase Not Applicable |
Recruiting |
3 |
61 Months |
15000 |
Dr Jane Vennik, Mrs Kate Martinson |
2020-11-12 |
| Evaluation of the Effectiveness of an Oral Antiseptic in Improving the Clinical Status, Decreasing Viral Load and Its Prolonged Action in Patients with COVID-19 |
Coronavirus disease 19 infection |
Tooth brushing alone, gargling / mouthwash a day alone, toothpaste alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Sao Paulo |
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior |
Brazil |
2020-08-10 |
|
34070620.6.0000.5417, 4.212.624, RBR-58ftdj, U1111-1255-3454 |
Phase Not Applicable |
Recruiting |
1 |
|
40 |
Bernardo da Fonseca Orcina, Paulo Sérgio da Silva Santos |
2020-11-06 |
| Aftogel and COVID-19 PCR test |
Coronavirus disease 19 infection |
Aftogel strip alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Exir Danesh Asia Co |
|
Iran |
2020-11-21 |
|
IR.MUI.REC.1399.520, IRCT20181208041886N2 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
60 |
Dr. Mohsen Saniei, Dr. Morteza Pourahmad |
2020-11-09 |
| Study of ZnAg Liquid Solution to Treat COVID-19 Symptomatic Participants |
Coronavirus disease 19 infection |
CNM-AgZn-17 alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Clene Nanomedicine Inc |
Azidus Brasil |
|
2020-12-31 |
2021-08-31 |
CNMZNAG.202, NCT04610138 |
Phase 2 Clinical |
Not yet recruiting |
0 |
8 Months |
238 |
Renata Lourencini, Robert Glanzman, MD |
2020-11-05 |
| Redploy: Lessons from the frontline: the impact of redeployment during COVID-19 on nurse wellbeing, performance and retention |
Coronavirus disease 19 infection |
|
|
|
Bradford Teaching Hospitals NHS Foundation Trust |
National Institute for Health Research (NIHR) |
UK |
2020-10-01 |
2022-03-31 |
ISRCTN18172749, NIHR132041, Redploy |
Phase Not Applicable |
Not yet recruiting |
3 |
18 Months |
48 |
Dr Jenni Murray, Prof Rebecca Lawton |
2020-11-03 |
| Effect of Melatonin in treatment of COVID-19 |
Coronavirus disease 19 infection |
melatonin alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Hamadan University of Medical Sciences |
|
Iran |
2020-10-22 |
|
IR.UMSHA.REC.1399.592, IRCT20200426047206N4 |
Phase 3 Clinical |
Recruiting |
1 |
|
60 |
Dr Saman Talebi, Saeed Bashirian, Salman Khazaei |
2020-11-03 |
| Evaluation of the effect of mucodentol on people with coronavirus |
Coronavirus disease 19 infection |
mucodentol (Khorraman Pharmaceutical Company) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Lorestan University |
|
Iran |
2020-04-25 |
|
IR.LUMS.REC.1399.046, IRCT20130428013151N2 |
Phase 0 Clinical |
No longer recruiting |
1 |
|
200 |
Behrooz Farzan, Ebrahim Fallahi |
2020-11-04 |
| Study of the effects of grapefruit extract on COVID-19 |
Coronavirus disease 19 infection |
grapefruit seed extract (Nutribiotic Company) plus lopinavir + ritonavir |
HIV protease inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Shaheed Beheshti Medical University |
|
Iran |
2020-04-21 |
|
IR.SBMU.RETECH.REC.1399.041, IRCT20140312016968N2 |
Phase Not Applicable |
No longer recruiting |
1 |
|
20 |
Dr. Afshin Zarghi, Dr. Aliakbar Velayati, Majid Marjani, Seyed Ali Ziai |
2020-11-03 |
| A clinical trial of COVID-19-specific T-cells for the treatment of COVID-19 |
Coronavirus disease 19 infection |
COVID-19-specific T-cells(Children's National Hospital) alone |
|
|
Children's National Hospital |
|
US |
|
|
|
Phase 1 Clinical |
Planned |
1 |
|
|
|
2020-11-02 |
| Infrastructure research for understanding the actual situation and pathophysiology of long-term complications of Coronavirus disease 2019 (COVID-19) |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
School of Medicine, Keio University |
Japanese Ministry of Health, Labor and Welfare |
Japan |
2020-11-02 |
|
UMIN000042299 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
2000 |
Koichi Fukunaga, Makoto Ishii |
2020-11-03 |
| VoViThel: SARS-COVID-Endotheliitis Study via Retinal Vascular Analysis (COVID-19) |
Coronavirus disease 19 infection, Ocular disease |
flicker-light stimulation alone, intensive care therapy alone, retinal vascular analysis alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Jena University Hospital |
|
Germany |
2020-09-14 |
|
2020-1805BO, DRKS00023334, VoViThel |
Phase Not Applicable |
Recruiting |
1 |
|
30 |
Richard Biedermann |
2020-11-04 |
| Cod Liver Oil for COVID-19 Prevention Study |
Coronavirus disease 19 infection, Respiratory tract infection |
Cod liver oil alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Oslo University Hospital |
Norwegian Institute of Public Health, University of Oslo |
Norway |
2020-11-10 |
2023-05-31 |
NCT04609423, REK-172796 |
Phase 4 Clinical |
Recruiting |
1 |
30 Months |
80000 |
Arne Søraas, MD, PhD, John Arne Dahl, PhD, Merete Ellingjord-Dale, PhD |
2020-11-13 |
| SECR-01: Efficacy and Safety of Two Hyperimmune Equine Anti Sars-CoV-2 in COVID-19 Patients |
Coronavirus disease 19 infection |
Variable regimens including Equine Imunoglobulin anti SARS Cov 2 , acetaminophen , chlortrimeton , cimetidine |
Histamine H2 receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Costa Rican social security box |
Ministry of Health of Costa Rica, Universidad De Costa Rica |
Costa Rica |
2020-09-06 |
2020-12-06 |
NCT04610502, R020-SABI-00259, SECR-01 |
Phase 2 Clinical |
Recruiting |
4 |
3 Months |
26 |
Alfredo Sanabria, PhD, Ann Echeverri, MD, Douglas Montero, MD, Henry Chan, MD, Ileana Balmaceda, MD, Jorge Jiménez, MD, Jose Pablo Madrigal, MD, José Acuña, MD, Juan Ignacio Silesky, MSc, Mario Sibaja, MD, Rodrigo Aguilar, MD, Taciano Lemos, MD, Willem Bujan, MBA |
2020-11-07 |
| Nano-COVID19: Treatment of Patients With Mild Coronavirus-19 (COVID-19) Disease With Methotrexate Associated to LDL Like Nanoparticles |
Coronavirus disease 19 infection |
didodecyl methotrexate (lipid nanoemulsion, myocardial infarction), University of Sao Paulo plus leucovorin |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo |
Hospital Santa Marcelina |
Brazil |
2020-10-27 |
2021-07-15 |
36746020.5.1001.0068, NCT04610567, Nano-COVID19 |
Phase 1/Phase 2 Clinical |
Recruiting |
3 |
8 Months |
100 |
Jose Salvador Oliveira, MD, PhD, Lucas Marinho, MD, Raul Cavalcante Maranhão, Raul Maranhão, MD, PhD, Rodrigo Esper, MD, PhD |
2020-11-07 |
| WIN COVID-19: Low dose lung X-ray therapy for COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
Antibiotics alone, Low dose radiotherapy alone, statins alone, Variable regimens including Alteplase , Convalescent plasma , Dexamethasone , Enoxiparin , Methylprednisolone , Mycobacterium w , N acetyl cysteine , Oxygen , Paracetamol , Remdesvir , Tocilizumab , Ulinastatin , Vitamin C , Vitamin D , Zinc , pirfenidone , thiamine |
Interferon gamma receptor agonist, MAPK gene modulator, PDGF receptor antagonist, TGF beta receptor antagonist, TLR-2 agonist, TLR-4 agonist, TLR-9 agonist, p38 MAP kinase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
HarshaMitra Superspecialty Cancer Centre and Research Institute, Sundaram Hospital |
|
India |
2020-11-06 |
|
CTRI/2020/10/028597, WIN COVID-19 |
Phase 2 Clinical |
Not yet recruiting |
1 |
|
61 |
Govindaraj Ganesan, Sasipriya P, Vivek Sundaram |
2020-11-04 |
| Psychological coping with the COVID-19-pandemic |
Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder, Psychiatric disorder |
Google Forms program alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Leukämie Lymphom Liga e.V.Universitätsklinikum Düsseldorf |
|
Germany |
2020-05-12 |
|
2020-975, DRKS00021756 |
Phase Not Applicable |
Recruiting |
1 |
|
9000 |
Jonas Jansen |
2020-11-05 |
| Trends of Symptoms in Patients Under Institutional Isolation in COVID-19 Pandemic in India - An Observational study |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
All India Institute of Medical Sciences |
|
India |
2020-10-26 |
|
CTRI/2020/10/028639 |
Phase 4 Clinical |
Not yet recruiting |
1 |
|
1000 |
Dr Balbir Kumar |
2020-11-03 |
| To assess the overall effect of COVID-19 on intent of treatment and staging of cancer |
Cancer, Coronavirus disease 19 infection |
|
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Max Super Speciality Hospital |
|
India |
2020-11-02 |
|
CTRI/2020/10/028648 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
350 |
Dr Aditi Chaturvedi |
2020-11-04 |
| Clinical trial to study the effect of Budesonide taken through inhalation in mild COVID cases |
Coronavirus disease 19 infection |
Budesonide alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
sparsh chest diseases center |
Department of Health and Family Welfare, Government of Gujarat |
India |
2020-10-23 |
|
CTRI/2020/10/028581 |
Phase 3 Clinical |
Not yet recruiting |
4 |
|
1000 |
Dr Anand Patel, Dr Jayeshkumar Dobariya, Dr Jigna Dave, Dr Parul Vadgama, Dr Tushar Patel |
2020-11-05 |
| Effectiveness of an online training module with lectures and videos regarding maternal and newborn care during COVID 19 pandemic on the knowledge and acceptability among nursing students |
Coronavirus disease 19 infection |
E - learning module alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
AIIMS Rishikesh |
|
India |
2020-10-26 |
|
CTRI/2020/10/028580 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
50 |
Levis Murry, cecilia mary |
2020-11-04 |
| Long-term Evolution of Pulmonary Involvement of Novel SARS-COV-2 Infection (COVID-19): Follow the COVID Study |
Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Policlinico S.Orsola-Malpighi |
|
Italy |
2020-07-30 |
2021-07-30 |
714/2020/OSS/AOUBO, NCT04605757 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
100 |
Dr. Stefano Nava, Irene Prediletto, MD-PhD, Irene Prediletto, MD-Phd, Stefano Nava, MD, Stefano Nava, MD, FERS |
2020-11-02 |
| Evaluate the Safety, Immunogenicity and Potential Efficacy of an rVSV-SARS-CoV-2-S Vaccine |
Coronavirus disease 19 infection |
VSV vector-based vaccine targeting spike glycoprotein (COVID-19), IIBR/Weizmann Institute of Science alone |
COVID19 Spike glycoprotein modulator |
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Israel Institute for Biological Research |
Ministry of Health, Israel |
Israel |
2020-10-28 |
2022-06-01 |
IIBR 20-001, NCT04608305 |
Phase 1/Phase 2 Clinical |
Recruiting |
2 |
19 Months |
1040 |
Eytan Ben Ami, Dr., Hadar Marcus, Dr., Noa Madar Balakirski, Dr., Yoseph Caraco, Prof. |
2020-11-04 |
| NICOVID: Evaluation of the Efficacy of Nicotine Patches in SARS-CoV2 (COVID-19) Infection in Hospitalized Patients |
Coronavirus disease 19 infection |
nicotine transdermal patch alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assistance Publique Hopitaux de Paris |
|
France |
2020-11-30 |
2022-06-30 |
2020-003743-28, APHP200529, NCT04608201, NICOVID |
Phase 3 Clinical |
Not yet recruiting |
1 |
19 Months |
220 |
Valérie POURCHER, MD, PhD, Zahir AMOURA, MD, PhD, Zahir AMOURA, MD,PhD |
2020-11-10 |
| Treat COVID-19 Patients With Regadenoson |
Coronavirus disease 19 infection, Lower respiratory tract infection, Lung inflammation, Lung injury |
regadenoson alone |
Adenosine A2a receptor agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Maryland Baltimore County |
|
US |
2020-11-01 |
2022-01-31 |
HP-00091372, NCT04606069 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
15 Months |
40 |
Christine L Lau, MD, MBA, Manal Al-Suqi, MSTC, Melissa Culligan, RN |
2020-11-05 |
| ComCor: Study of Socio-demographic Factors, Behaviors and Practices Associated With Infection With SARS-CoV-2 Responsible for COVID-19 |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Institut Pasteur |
Ipsos |
France |
2020-10-27 |
2021-06-30 |
2020-047, 2020-A02560-39, ComCor, NCT04607941 |
Phase Not Applicable |
Recruiting |
3 |
8 Months |
57720 |
Arnaud Fontanet, Pr, Carole Blanc, Christophe David, Faiza Omar, Nathalie Jolly, Tiffany Charmet, DVM, MPH |
2020-11-03 |
| Inhaled NO for the Treatment of Viral Pneumonia in Adults |
Coronavirus disease 19 infection, Viral pneumonia |
LungFit alone, nitric oxide alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Beyond Air Inc |
|
|
2020-11-07 |
2021-09-07 |
BA_VPLF_01, NCT04606407 |
Phase 2 Clinical |
Not yet recruiting |
0 |
10 Months |
90 |
Asher Tal, Meital Hatan, Rinat Kalaora |
2020-11-04 |
| PURIFY-OBS-1: PURIFY-OBS: Blood Purification With Seraph 100 Microbind Affinity Blood Filter for Treatment of Severe COVID19 Observational Study |
Acute lung injury, Adult respiratory distress syndrome, Coronavirus disease 19 infection, Respiratory failure |
Seraph 100 Microbind alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Henry M Jackson Foundation for the Advancement of Military Medicine |
Uniformed Services University of the Health Sciences |
US |
2020-11-20 |
2022-02-01 |
NCT04606498, PURIFY-OBS-1, PURIFY-OBS-1 |
Phase Not Applicable |
Not yet recruiting |
1 |
14 Months |
200 |
Ian Stewart, MD, Kevin Chung, MD, Marianne Spevak, BSHS, Sophie Haralson, Stephen Olsen, MD |
2020-11-06 |
| AirS: SARS-CoV-2 in Air (COVID-19) |
Coronavirus disease 19 infection |
air sampler alone, breath sampling alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital, Bonn |
|
Germany |
2020-11-16 |
|
398/20, AirS, DRKS00023435 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
15 |
Ricarda Schmithausen |
2020-11-03 |
| ELISA: Lubecker longitudinal study on Infections with SARS-CoV-2 (COVID-19) |
Coronavirus disease 19 infection |
SARS CoV-2 sequencing alone, brief smell identification test alone, enzyme-linked immunosorbent assay alone, metabolite test alone, peripheral blood mononuclear cell analysis alone, polymerase chain reaction test alone, serum antibody test alone, urine analysis alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universitatsklinikum Schleswig-Holstein Campus Lubeck, University of Lubeck |
Deutsche Forschungsgemeinschaft (DFG), German Federal Ministry of Education and Research |
Germany |
2020-05-06 |
|
20-150, DRKS00023418, ELISA |
Phase Not Applicable |
Recruiting |
1 |
|
3000 |
Alexander Katalinic, Christine Klein |
2020-11-03 |
| A study to assess safety and efficacy of emricasan for the potential treatment of mild-COVID-19 |
Coronavirus disease 19 infection |
emricasan (iv, liver transplantation/portal hypertension), Conatus alone |
Caspase inhibitor |
|
Amerimmune Llc |
|
US |
|
|
|
Phase 1 Clinical |
Not yet recruiting |
1 |
|
|
|
2020-11-17 |
| LAPCOV: Laparoscopy and COVID-19 Contamination |
Coronavirus disease 19 infection |
laparoscopy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assistance Publique Hopitaux de Paris |
|
France |
2020-11-01 |
2022-01-01 |
APHP200611, LAPCOV, NCT04608383 |
Phase Not Applicable |
Not yet recruiting |
1 |
14 Months |
20 |
Laura RUSCIO, Laura RUSCIO, MD, PhD |
2020-11-04 |
| MBI: Evaluation of Occupational Burnout and Stress Among Dentists in Covid-19 Pandemic |
Acute stress disorder, Coronavirus disease 19 infection |
|
|
|
Akdeniz University |
|
Turkey |
2020-03-09 |
2020-05-20 |
KAEK- 590, MBI, NCT04605692 |
Phase Not Applicable |
Completed |
1 |
2 Months |
706 |
Merve Özarslan |
2020-11-03 |
| CoRe (ADHOK): SARS-CoV-2 (COVID-19) registry for oncological and hematological patients in Germany |
Aplastic anemia, Cancer, Coronavirus disease 19 infection, Immune thrombocytopenic purpura, Myelodysplastic syndrome, Myeloproliferative disorder, Paroxysmal nocturnal hemoglobinuria |
|
|
|
Arbeitsgemeinschaft der Hamatologen und Onkologen im Krankenhaus e.V., St. Marien-Krankenhaus Siegen gem. GmbH |
Klinikum Bayreuth Klinik und Institut für Nuklearmedizin |
Germany |
2020-06-01 |
|
CoRe (ADHOK), DRKS00023012 |
Phase Not Applicable |
Recruiting |
26 |
|
170 |
Alexander Kiani, Romina Rösch |
2020-11-10 |
| Orthopedic Surgery in The Pandemic Era |
Coronavirus disease 19 infection |
SARS CoV-2 immunoglobulin G and IgM antibody test alone |
|
|
University of Indonesia |
|
Indonesia |
2020-04-01 |
|
UMIN000042052 |
Phase Not Applicable |
Completed |
1 |
|
35 |
Achmad Kamal, I Wayan Arya Mahendra Karda |
2020-11-02 |
| FIBRO-COVID: Pirfenidone compared to placebo in post-Covid19 pulmonary fibrosis |
Coronavirus disease 19 infection, Pulmonary fibrosis, Respiratory distress syndrome, Viral pneumonia |
Corticosteroid treatment alone, pirfenidone alone |
PDGF receptor antagonist, TGF beta receptor antagonist, p38 MAP kinase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Institut Investigació Biomèdica Bellvitge |
|
Spain |
2020-08-01 |
2021-08-01 |
2020-002518-42, FIBRO-COVID, NCT04607928 |
Phase 2 Clinical |
Recruiting |
8 |
12 Months |
148 |
Claudia Valenzuela, PI, David Jimenez, MD, PhD, Diego Castillo, PI, Eva Balcells, PI, Guadalupe Bermudo, MD, PhD, Guadalupe Bermudo, PI, Jacobo Sellarés, PI, Juan Rigual, PI, Karina Portillo, PI, Maria Molina, Maria Molina-Molina, MD, PhD, Piedad Usetti, MD, PhD, Rosalia Laporta, PI |
2020-11-04 |
| A retrospective, case series to evaluate the outcomes and biomarkers analyses among patients with COVID-19 treated with sarilumab in Italy |
Coronavirus disease 19 infection |
sarilumab alone |
IL-6 receptor antagonist |
|
Fondazione G Pascale |
|
Italy |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
15 |
|
2020-10-30 |
| CVP-Covid19: Cardiovascular Disease Progression and Prognosis in COVID-19 |
Cardiovascular disease, Coronavirus disease 19 infection, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universita di Bologna |
|
Italy |
2020-09-20 |
2021-12-31 |
CVP-Covid19, CV_SPP_COVID19, NCT04606732 |
Phase Not Applicable |
Recruiting |
1 |
15 Months |
2000 |
Maria Carla Re, Olivia Manfrini, Olivia Manfrini, MD |
2020-11-04 |
| PICN: Psychological Impact of Covid-19 Among Nurses in Hospital Sultanah Nora Ismail, Batu Pahat |
Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression |
|
|
|
HOSPITAL SULTANAH NORA ISMAIL, BATU PAHAT |
|
Malaysia |
2020-11-01 |
2021-03-31 |
NMRR-20-2291-55972, PICN, PICN 1.0, Version 1. 55972 |
Phase Not Applicable |
Not yet recruiting |
1 |
5 Months |
787 |
NURUL ASYHIKIN BINTI MOHD FADZIL |
2020-11-08 |
| ARBs CORONA II: Host Response Mediators in Coronavirus (COVID-19) Infection: Is There a Protective Effect of Losartan on Outcomes of Coronavirus Infection? |
Coronavirus disease 19 infection, Multiple organ failure |
losartan alone |
Angiotensin II AT-1 receptor antagonist, Angiotensin II receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of British Columbia |
Canadian Institutes of Health Research |
US, Belgium, Canada, Spain, Japan, France |
2020-10-09 |
2021-06-30 |
ARBs CORONA II, H20-01984, NCT04606563 |
Phase 3 Clinical |
Recruiting |
19 |
8 Months |
1372 |
Andre Kalil, MD, Anish Mitra, MD, Antonio Torres, MD, Brent Winston, MD, David Maslove, MD, David Sweet, MD, Francois Lamontagne, MD, Gregory Haljan, MD, J. Matthew Luther, MD, James A Russell, MD, John Boyd, MD, John Marshall, MD, Karen Tran, MD, Keith Walley, MD, Lynda Lazosky, Matthew Cheng, MD, Mitchell Levy, MD, Omar Sharif, MD, Peter Birks, MD, Pierre Asfar, MD, Puneet Mann, Puneet Mann, MSc, Rahim Kachra, MD, Robert Fowler, MD, Santiago Perez, MD, Steve Reynolds, MD, Taka-aki Nakada, MD, Thierry Dugernier, MD, Vicente Corrales-Medina, MD, Xavier Wittebol, MD |
2020-11-03 |
| VOCOVID: An open-label, single-center, investigator-initiated, exploratory trial to evaluate the safety and the antiviral effects of voclosporin versus tacrolimus in kidney transplant recipients (KTRs) with COVID-19 (SARS-CoV-2) |
Coronavirus disease 19 infection, Kidney transplantation |
voclosporin alone |
Calcineurin inhibitor, IL-2 receptor antagonist |
|
Aurinia Pharmaceuticals Inc |
|
Netherlands |
2020-10-27 |
|
VOCOVID |
Phase Not Applicable |
Recruiting |
1 |
|
20 |
Dr Aiko P.J. de Vries, Dr Y.K. Onno Teng |
2020-10-30 |
| Study to Find the Percentage of Cases Retaining COVID-19 IgG Antibodies 45 to 65 After They Have Tested Positive |
Coronavirus disease 19 infection |
ErbaLisa COVID-19 kit (Erba Corporate Services) alone, enzyme-linked immunosorbent assay alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Tata Main Hospital |
|
India |
2020-07-01 |
2020-08-30 |
152473, NCT04605952 |
Phase Not Applicable |
Completed |
1 |
1 Month |
201 |
Dr.Deb Sanjay Nag |
2020-11-03 |
| Study of Nebulized Ampion for the Treatment of Adult COVID-19 Patients With Respiratory Distress |
Coronavirus disease 19 infection, Respiratory distress syndrome |
Ampion (intranasal, inflammation), Ampio/DMI Biosciences alone, standard of care alone |
Stem cell antigen-1 inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ampio Pharmaceuticals Inc |
|
US |
2020-10-27 |
2021-03-31 |
AP-014, NCT04606784 |
Phase 1 Clinical |
Recruiting |
1 |
5 Months |
40 |
Ampio Pharmaceuticals, Inc, Ampio Pharmaceuticals, Inc. |
2020-11-16 |
| EQUINOX: A Study to Evaluate the Efficacy and Safety of Itolizumab in Subjects Hospitalized With COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
itolizumab alone |
T-cell differentiation antigen CD6 inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Equillium Inc |
Biocon Ltd |
US |
2020-11-30 |
2021-06-30 |
EQ001-20-001, EQUINOX, NCT04605926 |
Phase 3 Clinical |
Not yet recruiting |
1 |
7 Months |
800 |
Ivor S. Douglas, M.D, Maple Fung, MD, Stephanie Leyva |
2020-11-04 |
| WEAICOR: Wearables to Investigate the Long Term Cardiovascular and Behavioral Impacts of COVID-19 |
Cardiovascular disease, Coronavirus disease 19 infection |
Biostrap wristband device alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tulane University |
|
US |
2020-06-09 |
2022-06-30 |
2020-678, NCT04605965, WEAICOR |
Phase Not Applicable |
Recruiting |
2 |
24 Months |
100 |
Agnieska Drutel, PhD, Agnieszka Drutel, PhD, Agniezska Drutel, PhD, Arezu Bhatnagar, MD, MSCRM, Monique Rhodes, JD, Nassir Marrouche, MD |
2020-11-04 |
| AR0-CROWN: Effect of tenofovir / emtricitabine short course on viral clearance in outpatient SARS-CoV2 (COVID-19) infected patients |
Coronavirus disease 19 infection |
tenofovir disoproxil fumarate + emtricitabine (fixed dose), Gilead Sciences alone |
HIV-1 reverse transcriptase inhibitor, Nucleoside reverse transcriptase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
CHU de Caen |
|
France |
2020-10-15 |
|
20-070, 2020-001867-94, AR0-CROWN |
Phase 3 Clinical |
Recruiting |
1 |
|
180 |
Coordinator Investigator |
2020-11-02 |
| CYCLOVID: Evaluation of Alisporivir for the Treatment of Hospitalised Patients With Infections Due to SARS-CoV-2 (COVID-19) |
Coronavirus disease 19 infection |
alisporivir alone, standard of care alone |
Cytochrome P450 3A4 inhibitor, Peptidyl-prolyl cis-trans isomerase A inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assistance Publique Hopitaux de Paris |
Debiopharm SA |
France |
2020-11-01 |
2021-08-04 |
2020-002295-13, APHP200552, CYCLOVID, NCT04608214 |
Phase 2 Clinical |
Not yet recruiting |
2 |
9 Months |
100 |
Jean-Michel PAWLOTSKY, MD, PhD, Raphaël LEPEULE, MD |
2020-11-04 |
| NoCo-CoBio: Northern Colorado COVID-19 Biobank |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Colorado State University |
University of Colorado Health |
US |
2020-07-08 |
2022-07-30 |
20-10063H, NCT04603677, NoCo-CoBio |
Phase Not Applicable |
Recruiting |
4 |
24 Months |
200 |
Bridget Baxter, Elizabeth P Ryan |
2020-11-03 |
| PSY HCW Kel: The Psychological Impacts of Covid-19 Pandemic and Its Associated Socio-demographic Characteristics Among Government Health Care Workers in Kelantan, Malaysia |
Coronavirus disease 19 infection, Psychiatric disorder |
|
|
Healthy volunteers accepted |
Jabatan Kesihatan Negeri Kelantan |
|
Malaysia |
2020-11-01 |
2021-02-01 |
56611, NMRR-20-2306-56611, PSY HCW Kel |
Phase Not Applicable |
Status not specified |
1 |
3 Months |
|
Dr Noor Hashimah binti abdullah, Dr Tiong Wen Ning |
2020-10-30 |
| Morbidity Post COVID-19 - Investigation and call to action |
Coronavirus disease 19 infection |
Spirometry alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Griffith University, Royal Brisbane & Women's Hospital |
Royal Brisbane & Womens Hospital Research Foundation |
Australia |
2020-11-02 |
2021-07-30 |
ACTRN12620001114932p |
Phase Not Applicable |
Not yet recruiting |
2 |
8 Months |
200 |
Dr Jennifer Paratz |
2020-11-06 |
| SOBI: Anakinra, COVID-19, Cytokine Storm |
Coronavirus disease 19 infection, Respiratory failure, Systemic inflammatory response syndrome, Viral pneumonia |
anakinra alone |
Type I IL-1 receptor antagonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Weill Medical College of Cornell University |
Swedish Orphan Biovitrum AB |
US |
2020-11-30 |
2022-02-28 |
20-07022396, NCT04603742, SOBI |
Phase 2 Clinical |
Not yet recruiting |
1 |
15 Months |
100 |
Iris Y Navarro-Millan, MD, MSPH |
2020-11-04 |
| Best larnyngoscopes for tracheal intubation in covid patient with intubation box |
Coronavirus disease 19 infection |
CMAC video laryngoscope alone |
|
Young Adults (18-44 yrs) |
All India Institute of Medical Sciences |
|
India |
2020-11-04 |
|
CTRI/2020/10/028637 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
100 |
Dr Balbir Kumar |
2020-10-29 |
| Covid-19 infection during pregnancy and its effect on the mother and baby |
Coronavirus disease 19 infection |
|
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Christian Medical College and Hospital |
|
India |
2020-11-01 |
|
CTRI/2020/10/028636 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Kavita Mandrelle |
2020-10-30 |
| Efficacy of Mouthwash in Reducing Salivary Carriage of COVID-19 |
Coronavirus disease 19 infection |
Betadine mouthwash alone, Peridex alone, RT-PCR alone, hydrogen peroxide alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Ohio State University |
|
US |
2020-10-01 |
2020-11-30 |
2020H0346, NCT04603794 |
Phase 4 Clinical |
Recruiting |
1 |
2 Months |
60 |
David Hall, Associate Professor, David L Hall, DDS, Purnima Kumar, PhD,DDS |
2020-10-30 |
| Use of Virunil an ayurvedic medicie as a supportive treatment in management of COVID-19 |
Coronavirus disease 19 infection |
Virunil alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
NRI Medical College |
|
India |
2020-11-02 |
|
CTRI/2020/10/028635 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
|
150 |
Dr K V S Kumar Chowdary, Dr Kuricheti S S Siva Krishna, Dr V Siva Prabodh |
2020-10-29 |
| Evaluation of Self-Collected Saliva Samples Without Viral Transport Media for SARS-CoV-2 Testing Via RT-PCR |
Coronavirus disease 19 infection |
BioFire system alone, Cepheid system alone, Eppendorf Thermal Cycler PCR system alone, FilmArray system alone, GeneXpert system alone, Torch system alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
David Grant USAF Medical Center |
|
US |
2020-10-31 |
2021-02-28 |
FWH20200198H, NCT04604145 |
Phase Not Applicable |
Not yet recruiting |
1 |
4 Months |
600 |
Antoinette McNeary-Garvin, MSN, Benjamin D Ramos, MD, Benjamin Ramos, Maj |
2020-11-04 |
| Comparison of Efficacy of Dexamethasone and Methylprednisolone in Moderate-to-Severe COVID-19 Disease |
Coronavirus disease 19 infection |
Decadron alone, methylprednisolone (Pfizer) alone, Variable regimens including Decadron , convalescent plasma , methylprednisolone (Pfizer) , oxygen , tocilizumab |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Fatima Memorial Hospital |
|
Pakistan |
2020-05-30 |
2020-07-01 |
FMH-06-2020-IRB-763-M, NCT04603729 |
Phase 3 Clinical |
Completed |
1 |
1 Month |
100 |
Arzinda F Syeda, MBBS, FCPS, Khurshid A Khan, MBBS, FACM |
2020-10-30 |
| Impact of high flow oxygen therapy on outcomes of COVID-19 patients |
Coronavirus disease 19 infection, Hypoxia, Respiratory failure |
high flow nasal oxygen therapy alone, oxygen alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Rajendra Institute of Medical Sciences |
|
India |
2020-11-02 |
|
CTRI/2020/10/028634 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Dr Mohd Saif Khan |
2020-10-30 |
| Long-COVID19: Pilot Study Into LDN and NAD+ for Treatment of Patients With Post-COVID-19 Syndrome |
Coronavirus disease 19 infection |
IontoPatch alone, naltrexone plus nicotinamide adenine dinucleotide (NAD+) |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
AgelessRx |
|
US |
2020-11-30 |
2021-06-30 |
ALRX004, Long-COVID19, NCT04604704 |
Phase 2 Clinical |
Not yet recruiting |
1 |
7 Months |
60 |
Sajad Zalzala, MD |
2020-10-30 |
| CONFINeo: Lockdown Impact on Spontaneous Premature Birth in a Level III NICU |
Coronavirus disease 19 infection, Premature labor |
|
|
Newborn Infants (up to 5 months) |
Central Hospital, Nancy, France |
|
France |
2020-11-30 |
2021-05-31 |
2020PI168, CONFINeo, NCT04605172 |
Phase Not Applicable |
Not yet recruiting |
1 |
6 Months |
1000 |
Jean Michel Hascoet, Jean-Michel HASCOET |
2020-10-31 |
| Pilot Study Into the Use of Metformin and LDN for Patients With COVID-19 |
Coronavirus disease 19 infection |
metformin hydrochloride plus naltrexone |
AMP activated protein kinase stimulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
AgelessRx |
|
US |
2020-11-30 |
2021-05-31 |
ALRX003, NCT04604678 |
Phase 2 Clinical |
Not yet recruiting |
1 |
6 Months |
80 |
Sajad Zalzala, MD |
2020-10-30 |
| Post-COVID-19 Epidemic Depression Assessment in Adults in South Punjab Pakistan |
Coronavirus disease 19 infection, Depression |
|
|
|
Islamia University of Bahawalpur |
|
Pakistan |
2020-11-01 |
2020-11-15 |
NCT04604080, U1111-1260-1614 |
Phase Not Applicable |
Recruiting |
1 |
|
384 |
Anam Sharmeen, MA, Jafir Shirazi, PhD |
2020-11-06 |
| ICUcovid: Perceived Stress Among ICU Medical Staff During COVID-19 Crisis |
Acute stress disorder, Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Liege |
|
Belgium |
2019-06-26 |
2020-09-01 |
ICUcovid, NCT04604769, STRESSICUCOVID |
Phase Not Applicable |
Completed |
1 |
14 Months |
60 |
Anne-Sophie Nyssen, Audrey Vanhaudenhuyse |
2020-10-31 |
| TriACT: A Triple Combination Antiviral Coronavirus Therapy (TriACT) for COVID-19 |
Coronavirus disease 19 infection |
Variable regimens including hydroxychloroquine , nitazoxanide , ribavirin |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Rutgers University |
SYNAVIR |
US |
2020-10-31 |
2021-04-30 |
NCT04605588, PRO2020001862, TriACT |
Phase 2 Clinical |
Recruiting |
1 |
6 Months |
70 |
Helaine Noveck, MPH, Jeffrey L Carson, MD |
2020-11-11 |
| Angiotensin 1-7 as a Therapy in the Treatment of COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
angiotensin 1-7 alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Rambam Health Care Campus |
Constant Therapeutics LLC |
Israel |
2020-11-30 |
2024-04-30 |
0328-20-RMB, MOH_2020-11-02_009463, NCT04605887 |
Phase 2 Clinical |
Not yet recruiting |
1 |
41 Months |
120 |
Anat Ben Meir, BA, Etty Kruzel-Davila, DR, Etty Kruzel-Davila, Dr. |
2020-11-07 |
| CBD Oil for Reducing Emotional Impact of COVID-19 |
Acute stress disorder, Alcoholism, Anxiety disorder, Coronavirus disease 19 infection, Depression, Drug dependence, Sleep disorder |
CBD oil alone, hemp plant-derived cannabinoid intake alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
University of Texas Austin |
Way West Hemp Inc |
US |
2020-12-31 |
2021-12-31 |
2020-07-0138, NCT04603781 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
12 Months |
120 |
Cate Fischer, B.A., Cate Fischer, BA, Michael J Telch, Ph.D. |
2020-11-06 |
| Study of Niclosamide in Moderate Hospitalized Coronavirus-19 (COVID-19) Patients |
Coronavirus disease 19 infection, Lower respiratory tract infection |
repurposed niclosamide (oral/capsule, COVID-19), ANA Therapeutics alone, standard of care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
ANA Therapeutics |
|
US |
2020-10-07 |
2022-06-30 |
ANA001-001, NCT04603924 |
Phase 2/Phase 3 Clinical |
Recruiting |
4 |
20 Months |
436 |
Akash Bakshi, Andrew Bartynski, Andrew Bartyski, Doug Rank, MD |
2020-11-05 |
| Inspiratory Muscle Training in Patients With COVID-19 |
Coronavirus disease 19 infection |
aerobic exercise with cycle ergometer alone, breathing exercise alone, inspiratory muscle training alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sociedade Beneficente Israelita Brasileira Hospital Albert Einsten |
|
Brazil |
2020-06-01 |
2020-10-23 |
34931220.1.0000.0071, COVID19_IMPACT, NCT04603963 |
Phase Not Applicable |
Terminated |
1 |
4 Months |
55 |
Elaine Cristina Pereira |
2020-10-31 |
| BEMICOP: Comparison of Two Different Doses of Bemiparin in COVID-19 |
Coronavirus disease 19 infection, Viral pneumonia |
bemiparin alone |
Factor Xa antagonist, Heparin agonist, Low molecular weight heparin |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Clinica Universidad de Navarra, University of Navarra |
|
Spain |
2020-10-26 |
2021-07-31 |
BEMICOP, BEMICOP, NCT04604327 |
Phase 3 Clinical |
Recruiting |
12 |
9 Months |
164 |
David Filella, Elena Pina, Ernesto Botella, Jessica Abadía, Jorge Cuesta, Miguel Marcos, Ramon Lecumberri, MD, PhD, Ramon Lecumberri, Md, PhD, Ramón Lecumberri, MD, PhD, Rosa Vidal, Sonia Jiménez, Tania Galicia, Vanesa Sendín, Víctor Jiménez Yuste |
2020-10-31 |
| ACTION ON COVID-19: A Study to Test Whether BI-764198 Helps Lung Health of People Hospitalized With COVID-19 |
Adult respiratory distress syndrome, Coronavirus disease 19 infection |
BI-764198 alone |
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Boehringer Ingelheim International GmbH |
|
|
2020-10-28 |
2021-05-05 |
1434-0009, 2020-003211-96, ACTION ON COVID-19, NCT04604184 |
Phase 2 Clinical |
Recruiting |
0 |
6 Months |
90 |
Boehringer Ingelheim |
2020-11-04 |
| SAFE PAC Survey: online survey among anaesthesiologists about method of assessing breathing tube before administering anaesthesia duirng Covid 19 pandemic |
Coronavirus disease 19 infection |
practice of airway examination survey alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Malankara Orthodox Syrian Church Medical College, Kolenchery |
|
India |
2020-10-29 |
|
CTRI/2020/10/028696, SAFE PAC Survey |
Phase Not Applicable |
Not yet recruiting |
1 |
|
392 |
DrGirijananadan D Menon |
2020-10-29 |
| Can Vitamin C reduces COVID-19 symptoms |
Coronavirus disease 19 infection |
vitamin C alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Cancer Institute, Jhajjar, AIIMS |
|
India |
2020-11-05 |
|
CTRI/2020/10/028695 |
Phase 4 Clinical |
Not yet recruiting |
1 |
|
100 |
DR BALBIR KUMAR |
2020-10-29 |
| Expanded Access Program to Provide Bamlanivimab (LY-3819253) for the Treatment of COVID-19 |
Coronavirus disease 19 infection |
bamlanivimab alone |
COVID19 Spike glycoprotein modulator |
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Eli Lilly & Co |
AbCellera Biologics Inc |
|
|
|
18165, J2X-MC-Y001, NCT04603651 |
Phase Not Applicable |
Recruiting |
0 |
|
|
Contact Lilly at 1-800-LillyRx (1-800-545-5979) |
2020-11-11 |
| A survey to know effect of Corona pandemic on medical postgraduate student’s mental stress and their attitude to choose anesthesiology as a career |
Acute stress disorder, Coronavirus disease 19 infection, Psychiatric disorder |
Survey alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
All India Institute Of Medical Sciences, Rishikesh |
|
India |
2020-11-30 |
|
CTRI/2020/10/028672 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
500 |
Ashutosh Kaushal |
2020-10-29 |
| Role of NGAL and Cystatin C in Prediction of Acute Kidney Injury Covid-19 Infection |
Coronavirus disease 19 infection, Renal injury, Respiratory distress syndrome, Viral pneumonia |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Ain Shams University |
|
Egypt |
2020-10-30 |
2021-03-31 |
FMASU P82B/2020, NCT04603664 |
Phase Not Applicable |
Recruiting |
2 |
5 Months |
88 |
Sanaa Farag Mahmoud Wasfy, Wael S Abdelmegied, professor, eman wasfy, lecturer, sanaa fFM wasfy, MD, sanaa wasfy, lecturer, wael SO osman, MD |
2020-11-04 |
| Remdesivir effect in the treatment of corona |
Coronavirus disease 19 infection |
remdesivir alone |
COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Government Medical College, Bhavnagar |
|
India |
2020-10-30 |
|
CTRI/2020/10/028657 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
275 |
Dr Mitul Upadhyay |
2020-11-02 |
| A study to evaluate Easy Check COVID-19 IgM/IgG POC Antibody Test |
Coronavirus disease 19 infection |
Easy Check COVID-19 IgM/IgG POC Antibody Test alone |
|
|
Truvian Sciences Inc |
|
US |
|
|
|
Phase Not Applicable |
Status not specified |
1 |
|
|
Jerry Yeo, PhD |
2020-11-11 |
| Surgery complications rates in pre and post COVID era |
Coronavirus disease 19 infection |
general anesthesia alone, regional anesthesia alone |
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Homi Bhabha Cancer Hospital |
|
India |
2020-10-31 |
|
CTRI/2020/10/028649 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
888 |
Deep Kumar Jain |
2020-11-02 |
| Study to Investigate the Benefits of Colchicine in Patients With COVID-19 |
Coronavirus disease 19 infection |
colchicine alone, standard care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Liaquat University of Medical & Health Sciences |
Universidad De Murcia |
Pakistan |
2020-11-15 |
2021-06-14 |
LUMHS/REC/893, NCT04603690 |
Phase 3 Clinical |
Not yet recruiting |
1 |
7 Months |
102 |
Prof. Dr. Ikram Din Ujjan, MBBS, PhD, Prof. Dr. Saeed Khan, PhD |
2020-10-30 |
| PIOQ8: Effect of Pioglitazone on T2DM Patients With COVID-19 |
Coronavirus disease 19 infection, Non-insulin dependent diabetes |
anti-inflammatory therapy alone, antiviral therapy alone, pioglitazone alone, insulin glargine plus preprandial insulin |
Insulin ligand, Insulin receptor agonist, Insulin sensitizer, PPAR gamma agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Dasman Diabetes Institute |
Ministry of Health in Kuwait, Texas Diabetes Institute, University of Kuwait |
US, Kuwait |
2020-11-15 |
2021-06-29 |
NCT04604223, PIOQ8, RA HM-2020- 011 |
Phase 4 Clinical |
Not yet recruiting |
3 |
7 Months |
1506 |
Fahd Al-Mulla, PhD, Mohamed Abu-farha, Mohamed Abu-farha, PhD, Muhammed Abdul-Ghani, MD/PhD, Thamer Alessa, MD |
2020-10-30 |
| RINCOVID: Prevalence of COVID-19 in High Altitude: Insights From the Highest City of the World |
Coronavirus disease 19 infection |
COVID-PRESTO IgM/IgG test alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre d’Expertise sur l’Altitude EXALT |
|
Peru |
2020-10-26 |
2020-11-01 |
NCT04604249, RINCOVID, RINCOVID |
Phase Not Applicable |
Recruiting |
1 |
|
200 |
Benoit Champigneulle, MD, Ivan Hancco, MD, Samuel Verges, PhD, Samuel Vergès, PhD |
2020-10-30 |
| COVIDEIT: Electrical Impedance Tomography: Collapse in Dependent Areas as a Predictor of Response to Prone Position Ventilation in COVID-19 Acute Respiratory Distress Syndrome |
Coronavirus disease 19 infection, Respiratory distress syndrome |
electrical impedance tomography alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Centre de Recherches du Service de Sante des Armees (CRSSA) |
|
France |
2020-10-26 |
2022-04-30 |
2020-COVID19-16, COVIDEIT, NCT04603755 |
Phase Not Applicable |
Recruiting |
1 |
18 Months |
15 |
Michael CARDINALE, MD |
2020-11-11 |
| The Phase 1b, randomized, double-blind, placebo-controlled study designed to assess the safety, tolerability, and pharmacokinetic/pharmacodynamic profile of BEMPEG in adult patients with mild COVID-19 |
Coronavirus disease 19 infection |
bempegaldesleukin alone |
CD122 agonist, IL-2 receptor agonist |
|
Nektar Therapeutics |
|
US |
|
|
|
Phase 1b Clinical |
Recruiting |
1 |
|
|
|
2020-11-12 |
| Anxiety and Burnout in Anesthetists and Intensive Care Unit Nurses During COVID-19 Pandemic |
Anxiety disorder, Coronavirus disease 19 infection, Psychotic disorder |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Sisli Etfal Hospital |
|
Turkey |
2020-05-01 |
2020-06-01 |
1577, NCT04604119 |
Phase Not Applicable |
Completed |
1 |
1 Month |
104 |
Sultan Acar Sevinç |
2020-10-31 |
| To Evaluate the Safety and Efficacy of CT-P59 in Patients With Mild to Moderate Syptoms of Severe Acute Respiratory Syndrome COVID-19 |
Coronavirus disease 19 infection |
CT-P59 alone |
COVID19 Spike glycoprotein inhibitor, Moesin modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Celltrion Healthcare Co Ltd |
|
South Korea |
2020-09-25 |
2021-09-30 |
CT-P59 3.2, NCT04602000 |
Phase 2/Phase 3 Clinical |
Recruiting |
1 |
12 Months |
1020 |
ChangWoo Park, JiWoong Lim, Yeon-Sook Kim, MD, PhD |
2020-10-30 |
| COVID-19 in People With Primary Ciliary Dyskinesia |
Coronavirus disease 19 infection, Kartagener syndrome |
|
|
|
University of Bern |
EUROPEAN LUNG FOUNDATION, Kartagener Syndrome and PCD Association, PCD Australia, PCD Family Support Group, Support group Kartagener Syndrome and Primary Ciliary Dyskinesia, The Primary Ciliary Dyskinesia Foundation (PCDF), University Of Southampton |
Switzerland |
2020-05-31 |
2025-05-31 |
COVID-PCD, NCT04602481 |
Phase Not Applicable |
Recruiting |
2 |
60 Months |
1000 |
Claudia E Kuehni, Prof., Eva SL Pedersen, Dr. |
2020-11-10 |
| ITHACA: Clinical trial of the investigational drug AMY-101 for the treatment of patients with severe COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome |
AMY-101 alone |
Complement C3 inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Amyndas Pharmaceuticals |
|
Greece |
2020-10-23 |
|
2020-004408-32, AMY-101_ITHACA, ITHACA |
Phase 2 Clinical |
Recruiting |
1 |
|
62 |
Panagiotis Skendros, MD, PhD |
2020-10-29 |
| CAMOVID: Evaluation of Efficacy and Safety of Camostat Mesylate for the Treatment of SARS-CoV-2 Infection - COVID-19 in Ambulatory Adult Patients |
Coronavirus disease 19 infection |
camostat mesylate alone |
Serine protease inhibitor, Transmembrane serine protease 2 inhibitor, Trypsin inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assistance Publique Hopitaux de Paris |
|
France |
2020-11-30 |
2022-03-31 |
2020-003366-39, APHP200702, CAMOVID, NCT04608266 |
Phase 3 Clinical |
Not yet recruiting |
6 |
16 Months |
596 |
Christian Kassasseya, MD, Constance Guillaud, MD, David Boutboul, MD PhD, Dorothée Vallois, MD, Gaëtan Plantefève, MD, Mariela Skendi, MD, Pablo Bartolucci, MD PhD, Raphaël Lepeule, MD |
2020-11-06 |
| Preserving Compassionate End of Life Care in the Pandemic |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
McMaster University |
Canadian Institutes of Health Research |
Canada |
2020-03-16 |
2021-06-01 |
3WPC19, NCT04602520 |
Phase Not Applicable |
Recruiting |
1 |
14 Months |
135 |
Deborah Cook, Deborah Cook, MD MSc, Deborah J Cook, MD, France Clarke, RRT |
2020-11-03 |
| Ivermectin in Adults With Severe COVID-19 |
Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia |
ivermectin alone, standard management alone |
Chloride channel modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
CES University |
|
Colombia |
2020-10-31 |
2021-02-28 |
ECA-COVID-CES, NCT04602507 |
Phase 2 Clinical |
Not yet recruiting |
1 |
4 Months |
100 |
Federico Rodriguez-Vega, MD, Internist, Federico Rodríguez-Vega, MD, Francisco L Ochoa-Jaramillo, MD, MSc, Nora Cardona.-Castro, MD, MSc, PhD, Veronica Posada-Velez, MD, Internist |
2020-10-30 |
| COVID-19EXO2: Safety and Efficiency of Method of Exosome Inhalation in COVID-19 Associated Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
Mesenchymal Stem Cells Exosomes alone, standard therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Clinical Center of Cellular Technologies |
Samara Regional Clinical Hospital, Siberian State Medical University |
Russian Federation |
2020-10-01 |
2021-12-30 |
COVID-19 EXO EXTENDED, COVID-19EXO2, NCT04602442 |
Phase 2 Clinical |
Recruiting |
1 |
14 Months |
90 |
Olga Tyumina |
2020-10-30 |
| A case report to assess real-world effectiveness data of a patient with sickle cell disease (SCD) treated with voxelotor in the setting of COVID‐19 |
Coronavirus disease 19 infection, Sickle cell anemia |
voxelotor alone |
Hemoglobin alpha subunit modulator |
|
Global Blood Therapeutics Inc |
|
|
|
|
|
Phase 4 Clinical |
Status not specified |
0 |
|
|
|
2020-10-28 |
| A phase III trial to evaluate MT-2766 in the treatment of subjects with COVID-19 |
Coronavirus disease 19 infection |
MT-2766 alone |
TLR-9 agonist |
|
Medicago Inc |
|
|
2020-12-31 |
|
|
Phase 3 Clinical |
Planned |
0 |
|
|
|
2020-10-29 |
| The Evaluation of Nitric Oxide Generating Lozenges on Outcome in Newly Diagnosed COVID-19 Patient of African Americans |
Coronavirus disease 19 infection |
nitric oxide therapeutic (oral lozenge, COVID-19), Nitric Oxide Innovations alone |
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), African Ancestry |
Nitric Oxide Innovations LLC |
|
US |
2020-10-28 |
2021-07-31 |
IND150758 PILOT, NCT04601077 |
Phase 2/Phase 3 Clinical |
Recruiting |
4 |
9 Months |
100 |
John C Somberg, MD |
2020-11-04 |
| A phase II trial to evaluate MT-2766 in the treatment of subjects with COVID-19 |
Coronavirus disease 19 infection |
MT-2766 alone |
TLR-9 agonist |
|
Medicago Inc |
|
|
2020-11-01 |
|
|
Phase 2 Clinical |
Planned |
0 |
|
|
|
2020-10-29 |
| Survival Rates and Longterm Outcomes After COVID-19 |
Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia |
ICU treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Oslo University Hospital |
The Research Council of Norway |
Norway |
2020-09-16 |
2022-09-30 |
135310, NCT04601090 |
Phase Not Applicable |
Recruiting |
1 |
24 Months |
250 |
Kristin Hofsø, PhD |
2020-10-29 |
| Functional Recovery of Hospitalized Patients With COVID-19: The COREG Extension Study |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
McMaster University |
|
Canada |
2020-06-09 |
2021-09-30 |
COREG-EXTENSION_14567, NCT04602260 |
Phase Not Applicable |
Recruiting |
1 |
15 Months |
211 |
Hope Morrison, BA, Marla K Beauchamp, PhD |
2020-10-31 |
| A trial to evaluate AK-119 for the treatment of patients with mild to moderate COVID-19 |
Coronavirus disease 19 infection |
AK-119 alone |
CD73 antagonist |
|
Akeso Biopharma Inc |
|
US |
|
|
|
Phase Not Applicable |
Not yet recruiting |
1 |
|
|
|
2020-10-28 |
| CCP Cancer UK Companion Study |
Coronavirus disease 19 infection, Hematological neoplasm, Solid tumor |
|
|
|
The Clatterbridge Cancer Centre NHS Foundation Trust |
The University of Liverpool, University of Edinburgh, University of Oxford |
UK |
2020-10-31 |
2022-10-31 |
C1147, NCT04603105 |
Phase Not Applicable |
Not yet recruiting |
2 |
24 Months |
9000 |
Carlo Palmieri, Lance Turtle, Michael Stacckpoole, Bsc, Molly Mcevoy |
2020-11-03 |
| Be-Home-Kids: Feasibility and Effectiveness of Home-behavioral Program for Adolescents With Migraine |
Coronavirus disease 19 infection, Migraine, Migraine without aura |
Mindfulness by Smartphone alone |
|
Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) |
Fondazione IRCCS Istituto Neurologico Carlo Besta |
|
Italy |
2020-09-15 |
2021-12-31 |
BE-HOME-KIDS, Be-Home-Kids, NCT04604977 |
Phase Not Applicable |
Recruiting |
1 |
15 Months |
25 |
Licia Grazzi, Licia Grazzi, MD, Renato Mantegazza, MD |
2020-10-30 |
| Clinic-based HPV and COVID-19 Vaccine Promoting Intervention for AfAm Adolescents in Alabama |
Coronavirus disease 19 infection, Papillomavirus infection |
COVID-19 Vaccine alone, HPV vaccine alone, HPV vaccine uptake behavior and reducing sentiments alone |
|
Healthy volunteers accepted, Adolescents (13-17 yrs) |
University of Alabama at Birmingham |
|
US |
2021-01-01 |
2023-06-30 |
MISP #60590, NCT04604743 |
Phase Not Applicable |
Not yet recruiting |
1 |
30 Months |
4 |
Henna Budhwani |
2020-10-29 |
| DUO-EF-19: Point of Care Artificial Intelligence Tool for Heart Failure Diagnosis |
Cardiac failure, Coronavirus disease 19 infection |
artificial intelligence electrocardiogram alone, cardiac MRI alone, digital stethoscope alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Imperial College London |
|
|
2021-02-01 |
2022-10-01 |
285417, DUO-EF-19, NCT04601415 |
Phase Not Applicable |
Not yet recruiting |
0 |
20 Months |
1500 |
|
2020-10-29 |
| Phase II Study of Bemcentinib for the Treatment of COVID-19 in Hospitalized Patients |
Coronavirus disease 19 infection |
bemcentinib alone, standard of care alone |
Axl tyrosine kinase receptor inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
BerGenBio AS, IQVIA RDS (India) Pvt Ltd |
|
India |
2020-10-20 |
|
BGBC020, CTRI/2020/10/028602 |
Phase 2 Clinical |
Recruiting |
7 |
|
120 |
Dr Atul Arvind Joshi, Dr John Ramapuram, Dr Maheshkumar Sutariya, Dr Manojkumar Chopada, Dr Naresh Kumar, Dr Prathibha Pereira, Dr Sambit Sahu, Suneela Thatte |
2020-11-03 |
| Online cognitive behavioral therapy for distress in people who lost a loved one during the corona pandemic: A randomized waitlist-controlled trial |
Acute stress disorder, Coronavirus disease 19 infection, Major depressive disorder, Post traumatic stress disorder |
online cognitive behavioral therapy alone, psychoeducation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universiteit Utrecht |
|
Netherlands |
2020-07-01 |
2022-07-01 |
METC 20-446, NL8993 |
Phase Not Applicable |
Recruiting |
1 |
24 Months |
52 |
Lyanne Reitsma |
2020-10-30 |
| Digital Health Literacy Intervention for Disadvantaged Women During Corona |
Coronavirus disease 19 infection |
Digital Health Literacy Intervention alone, Health literacy video tutorial alone, Monthly group virtual meetings and Whatsapp group alone, Provision and guidance of a self-management alone, Virtual one-on-one weekly meetings alone |
|
Female, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Forman Christian College |
Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital, doctHERs |
|
2020-11-01 |
2021-06-01 |
FORMANCHRISTIANC, NCT04603092 |
Phase Not Applicable |
Not yet recruiting |
0 |
7 Months |
1000 |
Sara Rizvi Jafree |
2020-11-05 |
| Nurse Leadership for Hospital Infection Control |
Coronavirus disease 19 infection, Infectious disease |
Intervention for COVID-19 preventive protocols alone, digital communication of written material alone, monthly online training and discussion alone |
|
Healthy volunteers accepted, Female |
Forman Christian College |
King Edward Medical University, Shahid Hussain Foundation, Shalamar Medical and Dental College |
|
2020-11-01 |
2021-03-01 |
NCT04603079, NURSELEADERSHIP |
Phase Not Applicable |
Not yet recruiting |
0 |
4 Months |
200 |
Sara Rizvi Jafree |
2020-11-05 |
| EN-COVID-19: Enduring Happiness and Continued Self-Enhancement (ENHANCE) for COVID-19 |
Anxiety disorder, Coronavirus disease 19 infection, Insomnia, Post traumatic stress disorder |
Enduring Happiness and Continued Self-Enhancement (ENHANCE) for COVID-19 alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of British Columbia |
University of Utah, University of Virginia |
Canada |
2020-10-14 |
2020-12-31 |
EN-COVID-19, NCT04602832, UNIVERSITY OF BRITISH COLUMBIA |
Phase Not Applicable |
Recruiting |
1 |
2 Months |
350 |
Lesley Lutes |
2020-11-05 |
| How Does Mindfulness Meditation Buffer the Negative Effects of Pain and Suffering in the COVID-19 World? (Healthy Sample) |
Coronavirus disease 19 infection, Pain |
Book listening alone, Mindfulness meditation alone, focussed-attention mindfulness meditation alone, sham mindfulness meditation alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Queensland |
University of California San Diego, University of Sydney |
Australia |
2020-10-28 |
2021-03-31 |
2019000347-S4C, NCT04602312 |
Phase Not Applicable |
Recruiting |
2 |
5 Months |
624 |
Jonathan Davies, MSc, Melissa Day, PhD |
2020-11-14 |
| How Does Mindfulness Meditation Buffer the Negative Effects of Pain and Suffering in the COVID-19 World? (Pain Sample) |
Coronavirus disease 19 infection, Pain |
Mindfulness meditation alone, focussed-attention mindfulness meditation alone, sham mindfulness meditation alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Queensland |
University of California San Diego, University of Sydney |
Australia |
2020-10-28 |
2021-03-31 |
2019000347-S4P, NCT04602286 |
Phase Not Applicable |
Recruiting |
2 |
5 Months |
292 |
Jonathan Davies, MSc, Melissa Day, PhD |
2020-11-13 |
| Physiotherapist-led Exercise Within Cardiac Rehabilitation and Paroxysmal Atrial Fibrillation and COVID-19 |
Atrial fibrillation, Coronavirus disease 19 infection |
Physiotherapist-led exercise-based cardiac rehabilitation alone, Threshold Inspiratory Muscle Trainer (Respironics Inc) alone, central circulatory exercise alone, inspiratory muscle training alone, muscle exercise alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Vastra Gotaland Region |
|
Sweden |
2021-01-31 |
2025-10-31 |
273293, NCT04600713 |
Phase Not Applicable |
Not yet recruiting |
1 |
57 Months |
180 |
Maria Borland, PhD RPT, Åsa Cider, PhD RPT |
2020-11-03 |
| STAMP: Strategies to Assist With Management of Pain |
Coronavirus disease 19 infection, Lower back pain |
Mindfulness Meditation alone, usual care alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Wisconsin-Madison |
Patient Centered Outcome Research Institute |
US |
2017-06-30 |
2021-07-15 |
2017-0353, A532007, NCT03115359, SMPH/FAMILY MED/FAMILY MED, STAMP |
Phase Not Applicable |
Recruiting |
4 |
48 Months |
766 |
Aleksandra E Zgierska, MD PhD, Amy Watson, BS, Bruce P Barrett, MD PhD, Cindy A Burzinski, MS, Eric Garland, PhD, Lauren Papianou, BS, Robert Edwards, PhD |
2020-11-07 |
| Adaptive, randomized, open, controlled study to assess the efficacy and safety of Nobazit, film-coated tablets, 250 mg (JSC Avexima, Russia) in the treatment of hospitalized patients with an infection caused by the SARS-CoV-2 virus (COVID-19) |
Coronavirus disease 19 infection |
enisamium iodide (Nobazit), Avexima alone |
|
|
Avexima OJSC |
|
Russian Federation |
2020-10-27 |
2021-06-10 |
Nobazit-COVID-19-T-III-2020 |
Phase 3 Clinical |
Status not specified |
13 |
7 Months |
160 |
|
2020-10-29 |
| Odorat-Covid: Evaluation of Two Methods of Olfactory Rehabilitation in Post-viral Loss of Smell: Classic and Intensive |
Coronavirus disease 19 infection, Dysomia, Olfactory nerve disorder |
smell the odors of the olfactory rehabilitation kit according to the intensive method alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Central Hospital, Nancy, France |
|
France |
2020-07-01 |
2021-01-01 |
2020PI098, NCT04598763, Odorat-Covid |
Phase Not Applicable |
Recruiting |
1 |
6 Months |
80 |
Duc Trung NGUYEN, Duc Trung NGUYEN, MD, PhD, MPH, Julie Lecomte |
2020-10-31 |
| COVID-CARE: COVID-19, Chronic Adaptation and Response to Exercise |
Coronavirus disease 19 infection |
Aerobic Exercise Training alone, Education alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Institutes of Health Clinical Center |
|
US |
2020-11-20 |
2023-12-31 |
000102-CC, 10000102, COVID-CARE, NCT04595773 |
Phase 1/Phase 2 Clinical |
Not yet recruiting |
1 |
37 Months |
90 |
COVID-CARE Rehab Team, Leighton Chan, M.D. |
2020-11-17 |
| Detection of COVID-19 Using Breath Analysis - Validation Study (COVID-19) |
Coronavirus disease 19 infection |
Breath biopsy analysis alone, RT-PCR alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Scentech Medical Technologies Ltd |
|
Israel |
2020-11-12 |
2021-02-28 |
COV-2-SMC-2020, NCT04602949 |
Phase Not Applicable |
Not yet recruiting |
1 |
3 Months |
4000 |
Natalie Dror, PhD, Shai Efrati, Shai Efrati, MD |
2020-10-30 |
| ANTICOV EPI: Factors affecting transmission of SARS-CoV-2 in Households of SARS-CoV-2 patients in Sub-Saharan Africa Ancillary study of the ANTICOV Study: An open-label, multicenter, randomized, adaptive platform trial of the safety and efficacy of several therapies, including antiviral therapies, versus control in mild / moderate cases of COVID-19 |
Coronavirus disease 19 infection |
Hydroxychloroquine alone, lopinavir + ritonavir alone |
HIV protease inhibitor |
Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Barcelona Institute for Global Health, Bernhard-Nocht-Institute for Tropical Medicine, Drugs for Neglected Diseases Initiative, Ifakara Health Institute |
|
Equatorial Guinea, Kenya, Ghana, Mozambique |
2020-11-02 |
2021-06-01 |
ANTICOV EPI, PACTR202010718451278 |
Phase Not Applicable |
Not yet recruiting |
4 |
7 Months |
2800 |
James Arkinstall, MarcAlain Widdowson, Nathalie Strub Wourgaft |
2020-10-29 |
| Early Detection of COVID-19 Using Breath Analysis |
Coronavirus disease 19 infection |
ReCIVA breath sampler alone, breath biopsy sampling alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Scentech Medical Technologies Ltd |
|
Israel |
2020-09-22 |
2020-12-30 |
COV-2-IDF, NCT04602884 |
Phase Not Applicable |
Suspended |
1 |
3 Months |
50 |
Natalie Dror, PhD |
2020-11-03 |
| VBW: Virtual Assisted Living |
Coronavirus disease 19 infection, Muscle weakness |
ambient assisted living system scanning alone, virtual assisted living preventive care alone |
|
Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
BKK VBU |
Bahn BKK, DAK Gesundheit, HOWOGE Wohnungsbaugesellschaft mbH, Innovationsausschuss beim Gemeinsamen BundesausschussProjektträger DLR, Philips Medical Systems Technologies Ltd |
Germany |
2020-11-02 |
|
DRKS00023171, EA1/032/20, VBW |
Phase Not Applicable |
Not yet recruiting |
1 |
|
207 |
Anne Gersitz, Johanna Nordheim |
2020-11-05 |
| Training Load Management in Three Professional Tennis Players During COVID-19 Lockdown: a Case Series Study |
Coronavirus disease 19 infection |
training load monitoring alone |
|
Healthy volunteers accepted, Male |
Kine Kinesiologia Deportiva y Funcional |
|
Argentina |
2019-12-15 |
2021-01-15 |
NCT04602637, TLT01 |
Phase Not Applicable |
No longer recruiting |
1 |
13 Months |
3 |
Diego Mendez, PT |
2020-10-29 |
| Knowledge Attitude and Practice of Hand hygiene among Nursing Assistants and Trolley workers in a COVID-19 care units |
Coronavirus disease 19 infection |
questionnaire alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) |
Government Medical College Kannur |
|
India |
2020-11-05 |
|
CTRI/2020/10/028600 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Dr Venugopalan A K |
2020-10-29 |
| CoPa: Handling and coping with the corona pandemic (Covid-19) and its physical and psychological effects |
Coronavirus disease 19 infection, Psychiatric disorder |
|
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Lubeck |
Universitätsklinikum Schleswig-Holstein |
Germany |
2020-04-05 |
|
20-118, CoPa, DRKS00023393 |
Phase Not Applicable |
Recruiting |
1 |
|
5000 |
Elke Peters |
2020-11-05 |
| Factors Associated with Covid-19 Infection in Kinta District, Perak: A Case-Control Study |
Coronavirus disease 19 infection |
|
|
|
KINTA DISTRICT HEALTH OFFICE |
|
Malaysia |
2021-01-01 |
2021-02-28 |
56860, NMRR-20-2286-56860 |
Phase Not Applicable |
Not yet recruiting |
1 |
2 Months |
|
Dr Asraf Ahmad bin Qamruddin |
2020-11-05 |
| Covid-19 and Major Organ Thromboembolism: Manifestations in Neurovascular and Cardiovascular Systems |
Cardiovascular disease, Cerebrovascular disease, Coronavirus disease 19 infection, Thromboembolism |
|
|
|
Hospital Kuala Lumpur |
|
Malaysia |
2020-10-23 |
2020-10-31 |
56982, NMRR-20-2283-56982 |
Phase Not Applicable |
Status not specified |
1 |
|
|
Dr Presaad Pillai A/L Perianen |
2020-10-28 |
| The evaluation of efficacy of favipiravir in patients with mild-to-moderate COVID-19 |
Coronavirus disease 19 infection |
favipiravir (Dr. Abidi Pharmaceutical Co) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Dr.Abidi's Pharmaceutical Laboratories |
|
Iran |
2020-10-31 |
|
IR.TUMS.IKHC.REC.1399.215, IRCT20201005048936N1 |
Phase 3 Clinical |
Recruiting |
3 |
|
126 |
Ali Rakei, Ayat Ahmadi, Mahboubeh Hajabdolbaghi, Mahshid Talebi Taher, Masoud Mardani |
2020-11-02 |
| COP20: Convalescent Plasma in the Treatment of Covid-19 |
Coronavirus disease 19 infection, Respiratory disease |
convalescent plasma alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Skåne University Hospital |
|
Sweden |
2020-04-25 |
2022-02-28 |
COP20, COVID CONVALESCENT PLASMA, NCT04600440 |
Phase 2 Clinical |
Recruiting |
1 |
22 Months |
100 |
Magnus Rasmussen, MD, Prof, Maria N Lundgren, MD, Mona Landin-Olsson, MD, Prof |
2020-10-30 |
| Early Detection of COVID-19 Using Breath Analysis - Feasibility Study |
Coronavirus disease 19 infection |
ReCIVA Breath Sampler alone, breath biopsy sampling alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Scentech Medical Technologies Ltd |
|
Israel |
2020-07-03 |
2021-01-30 |
COV-2-2020, NCT04602871 |
Phase Not Applicable |
Recruiting |
2 |
6 Months |
108 |
David Shitrit, MD, Natalie Dror, PhD, Victor Novac, MD |
2020-11-05 |
| Mechanically assisted Airway clearence COVID -19 |
Coronavirus disease 19 infection |
mechanically assisted airway clearance alone |
|
|
Hospital Sungai Buloh |
|
Malaysia |
2020-11-02 |
2021-07-01 |
55173, NMRR-20-2280-55173 |
Phase Not Applicable |
Status not specified |
1 |
8 Months |
|
DR AKMAL HAFIZAH ZAMLI, swarna lata krishnabahawan |
2020-10-29 |
| DISH19: Dietary supplements use among health-care workers during the COVID-19 pandemic in Malaysia: a cross-sectional study |
Coronavirus disease 19 infection |
Dietary supplements alone |
|
|
Seberang Jaya Hospital |
|
Malaysia |
2020-12-01 |
2021-06-30 |
56853, DISH19, NMRR-20-2275-56853 |
Phase Not Applicable |
Status not specified |
1 |
7 Months |
|
Dr Looi Irene, Lee Heoy Teng |
2020-10-28 |
| OCTA Study: Retinal Vascular Changes in SARS-CoV-2 Patients |
Coronavirus disease 19 infection |
optical coherence tomography angiography alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universita degli Studi di Napoli Federico II |
|
Italy |
2020-09-20 |
2020-10-22 |
2020/03, NCT04601012 |
Phase Not Applicable |
Completed |
1 |
1 Month |
40 |
Gilda Cennamo |
2020-10-29 |
| HEPMAB: Clinical Efficacy of Heparin and Tocilizumab in Patients With Severe COVID-19 Infection: a Randomized Clinical Trial |
Coronavirus disease 19 infection |
Variable regimens including enoxaparin sodium , heparin , tocilizumab |
Low molecular weight heparin |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Sao Paulo |
Conselho Nacional de Desenvolvimento Cientifico e Tecnologico - CNPq |
Brazil |
2020-10-20 |
2021-12-31 |
5057/20/086, HEPMAB, NCT04600141 |
Phase 3 Clinical |
Not yet recruiting |
1 |
14 Months |
308 |
Lucas TC Ribeiro, Ludhmila A Hajjar, MD, PhD |
2020-10-30 |
| COVID-19 Tests: Nasopharyngeal Swab versus Saliva Collected With Salivette Cortisol for Viral RNA Sampling for RT-qPCR |
Coronavirus disease 19 infection |
Kylt detection kit alone, Salivette alone, TaqPath COVID-19 CE-IVD RT-PCR kit alone, cobas SARS-CoV-2 PCR test alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Boehringer Ingelheim International GmbH |
|
Mexico |
2020-10-20 |
2020-11-13 |
0352-2150, NCT04599959 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
80 |
|
2020-11-12 |
| ComICU: Communication in ICU During COVID-19 |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
NMC Specialty Hospital |
|
United Arab Emirates |
2020-11-01 |
2020-12-31 |
COMICU, ComICU, NCT04602351 |
Phase Not Applicable |
Not yet recruiting |
1 |
2 Months |
200 |
Gunjan Chanchalani, MD FNB, Prashant Nasa, Prashant Nasa, MD EDICM |
2020-10-29 |
| Venous Thromboembolism in Patients with COVID-19 in Japan Study |
Coronavirus disease 19 infection, Thromboembolism |
|
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kuwana East Medical Center |
|
Japan |
2020-11-01 |
|
UMIN000042235 |
Phase Not Applicable |
Recruiting |
1 |
|
200 |
Norikazu Yamada, Yugo Yamashita |
2020-10-29 |
| Long-term, Follow-up Findings of Inpatients for COVID-19 Pneumonia |
Coronavirus disease 19 infection, Viral pneumonia |
Cardiopulmonary exercise testing alone, spirometry alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Koç University Hospital |
|
Turkey |
2020-10-15 |
2021-03-01 |
2020.188.IRB1.056, NCT04599998 |
Phase Not Applicable |
Recruiting |
1 |
4 Months |
37 |
Benan Çağlayan, Prof Dr, Fatma Işıl Uzel, MD |
2020-11-06 |
| PRESECO: The Prevent Severe COVID-19 (PRESECO) Study |
Coronavirus disease 19 infection |
favipiravir alone |
RNA polymerase inhibitor |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Appili Therapeutics Inc |
|
US |
2020-11-30 |
2021-10-31 |
ATI0220, NCT04600895, PRESECO |
Phase 3 Clinical |
Not yet recruiting |
1 |
11 Months |
826 |
|
2020-10-29 |
| Co-CAT: Child anxiety treatment in the context of COVID-19 |
Anxiety disorder, Coronavirus disease 19 infection |
online psychological intervention (OSI) alone, therapist support alone |
|
Preschool Children (2-5 yrs), Children (6-12 yrs) |
University of Oxford |
United Kingdom Research & Innovation |
UK |
2020-09-01 |
2021-08-31 |
Co-CAT, IRAS 288074, CPMS 46902, ISRCTN12890382 |
Phase Not Applicable |
Not yet recruiting |
2 |
12 Months |
560 |
Mrs Taylor |
2020-10-30 |
| The protective effect of powered air purifying respirators during chest compressions: A simulation study |
Coronavirus disease 19 infection |
Mask Fitting Tester ((SIBATA Scientific Technology Ltd) alone, powered air purifying respirator (PAPR) alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Nagoya University |
Nakatani foundation |
Japan |
2020-12-01 |
|
UMIN000042239 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
54 |
Yukari Goto |
2020-10-29 |
| An essential research study to advance the use of telehealth for rehabilitation in response to public health crises such as the COVID-19 pandemic |
Brain injury, Coronavirus disease 19 infection, Spinal cord injury, Stroke |
telehealth for rehabilitation alone |
|
|
Brooks Rehabilitation Clinical Research Center, Inc |
Madonna Rehabilitation Hospital, Mary Free Bed Rehabilitation Hospital |
US |
|
|
|
Phase Not Applicable |
Recruiting |
3 |
|
|
Dr. Judith Burnfield, Dr. Raine Osborne, Jason Peoples, Kenneth Ngo, MD |
2020-10-27 |
| Assessment of SARS CoV-2 seroprevalence and clinical profiling of COVID Unsuspected patients attending Otorhinolaryngology Department at AIIMS Jodhpur |
Coronavirus disease 19 infection |
IgM and IgG antibody testing alone |
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
AIIMS Jodhpur |
|
India |
2020-11-02 |
|
CTRI/2020/10/028598 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
50 |
Dr Amit Goyal, Dr Nitika Goyal |
2020-10-29 |
| The Effects of Narrative Exposure Therapy on COVID-19 Patients with Post-Traumatic Stress Disorder: A Randomized Controlled Trial |
Coronavirus disease 19 infection, Post traumatic stress disorder |
narrative exposure therapy alone |
|
|
Xiangyang Central Hospital |
|
China |
2020-02-28 |
|
ChiCTR2000039369 |
Phase 0 Clinical |
No longer recruiting |
2 |
|
111 |
Fan Ying |
2020-10-29 |
| The clinical characteristics and the etiology of COVID-19 infected patients with myocardial damage |
Coronavirus disease 19 infection, Heart injury |
|
|
|
Tongji Hospital, Huazhong University of Science and Technology, Tongji Medical College |
|
China |
2020-10-30 |
|
ChiCTR2000039364 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
200 |
Cheng Wang, FengZhu, ZhouMin |
2020-10-28 |
| An open-label, prospective study to evaluate RLF-100 in patients admitted to an intensive care unit (ICU) with critical COVID-19 and respiratory failure |
Coronavirus disease 19 infection, Respiratory failure |
aviptadil (inhaled, sarcoidosis/acute lung injury/acute respiratory distress syndrome associated COVID-19), Relief Therapeutics Holding alone |
Adrenergic receptor antagonist, VIP receptor agonist |
|
NeuroRx Inc, Relief Therapeutics Holding AG |
|
|
|
|
|
Phase 2 Clinical |
Status not specified |
0 |
|
|
|
2020-10-26 |
| A trial to evaluate PGX-YBG for the treatment of patients with COVID-19 |
Coronavirus disease 19 infection |
PGX-YBG alone |
|
|
Ceapro Inc |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
|
|
2020-10-26 |
| EAT COVID: An investigator initiated, randomized, Phase II clinical trial evaluating its eftilagimod alpha (“efti” or “IMP321”) in hospitalized patients with COVID-19 |
Coronavirus disease 19 infection |
eftilagimod alfa alone, standard care alone |
HLA class II antigen stimulator |
|
Immutep Ltd |
University Hospital Pilsen |
Czech Republic |
|
|
EAT COVID |
Phase 2 Clinical |
Recruiting |
1 |
|
110 |
Dr. Dalibor Sedlacek, Dr. Marek Nalos,, Martin Matejovic |
2020-10-26 |
| A phase Ib clinical study to assess ProTrans in the treatment of subjects with COVID-19 |
Coronavirus disease 19 infection |
ProTrans alone |
|
|
NextCell Pharma AB |
Karolinska Trial Alliance |
Sweden |
|
|
|
Phase 1b Clinical |
Not yet recruiting |
1 |
|
9 |
Doctor Tomasz Oldak, Professor Dominique Farge, Professor Edvard Smith, Professor Farge, Professor Josefin Sundh |
2020-11-04 |
| SARS-CoV-2 (COVID-19) Immune Surveillance Among a Population Based Sample of Adults in Florida |
Coronavirus disease 19 infection |
SARS-CoV-2 antibody analysis alone, Weck-cel swab collection alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
H Lee Moffitt Cancer Center and Research Institute |
Merck Sharp & Dohme Corp |
US |
2020-10-09 |
2022-10-09 |
MCC-20635, NCT04596579 |
Phase Not Applicable |
Recruiting |
2 |
24 Months |
1200 |
Anna R Giuliano, PhD |
2020-10-27 |
| oXAKI-COV: Efficacy and Safety of a Highly Selective Semipermeable Membrane (AN69 oXiris) versus (Standard AN69) in COVID-19 |
Coronavirus disease 19 infection, Inflammatory disease, Renal injury |
AN69 oXiris alone, continuous renal replacement therapy alone, vasopressor therapy alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Instituto Nacional de Ciencias Medicas y Nutricion |
|
Mexico |
2020-10-02 |
2022-03-30 |
NCT04597034, NMM-3401-20-20-1, oXAKI-COV |
Phase Not Applicable |
Recruiting |
1 |
17 Months |
35 |
Mauricio Arvizu-Hernández, MD, Olynka Vega Vega, MD, Olynka Vega-Vega, MD, Ricardo Correa Rotter, MD, Ricardo Correa-Rotter, MD |
2020-10-28 |
| Vitamin D3 Supplementation to Prevent Respiratory Tract Infections |
Coronavirus disease 19 infection, Respiratory tract infection |
vitamin D, Cooper alone |
|
Healthy volunteers accepted, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
The Cooper Health System |
The Won Sook Chung Foundation |
|
2020-10-31 |
2021-11-30 |
20-455, NCT04596657 |
Phase Not Applicable |
Not yet recruiting |
0 |
13 Months |
2099 |
Noud van Helmond, MD |
2020-11-05 |
| Study to Evaluate Efficacy and Safety of 'Viracide' in the Management of Corona Virus Disease 2019 (COVID-19) |
Coronavirus disease 19 infection |
ViraCide alone, standard of care alone |
|
Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
|
ProRelix Services LLP |
India |
2020-09-16 |
2021-01-30 |
NCT04596085, NS-VC-CT01-20 |
Phase Not Applicable |
Recruiting |
2 |
4 Months |
124 |
Dr Ninad Naik, MD(Ayurveda), Dr. A Gopal Rao, MD Medcine, Dr. A Gopal Rao, MD(Med), Dr.Mahir Abduldaim, Dr.Ninad Naik, MD(Ayurveda), Muralidhar Gudla, Niranjan Andhalkar, Sohal Pendse |
2020-11-05 |
| APCC-19: Chemoprevention Clinical Trial of COVID-19: Hydroxychloroquine Post Exposure Prophylaxis |
Coronavirus disease 19 infection |
hydroxychloroquine alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Regional Center for Disease Control and Prevention |
Farhat Hached University Hospital, Fattouma Bourguiba University Hospital |
Jordan |
2020-10-27 |
2021-01-31 |
APCC-19, APCC-19, NCT04597775 |
Phase 2/Phase 3 Clinical |
Not yet recruiting |
1 |
3 Months |
93 |
Amer A Amous, MD, Munir A Abu-Helalah, PhD, Munir Abu-Helalah, PHD, Wissem Hachfi, MD |
2020-11-05 |
| Predicting the role of resilience, reactance, social solidarity and positive schemas on Pandemic-related Anxiety |
Anxiety disorder, Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
LVR-Klinikum DüsseldorfKliniken der Heinrich-Heine-Universität Düsseldorf |
|
Germany |
2020-11-01 |
|
2020-1071, DRKS00023321 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
85 |
Milenko Kujovic |
2020-10-29 |
| Prevalence and Temporal Evolution of Chest Radiographic Findings in Filipino Patients with Coronavirus Disease 2019 (COVID-19) |
Coronavirus disease 19 infection |
chest radiographic findings alone |
|
|
University of the Philippines |
|
Philippines |
2020-05-15 |
2021-01-15 |
PHRR201012-003027 |
Phase Not Applicable |
No longer recruiting |
1 |
8 Months |
|
Jarold P. Pauig, Johanna Patricia Adevoso-Cañal, Julian A. Santos, Rosanna E. Fragante |
2020-11-06 |
| The Knowledge, Attitudes and Practices of Resident Physicians in Southern Philippines Medical Center, Davao City Philippines towards COVID-19: a cross-sectional study |
Coronavirus disease 19 infection |
Knowledge levels, attitudes and practices alone |
|
|
Southern Philippines Medical Center |
|
Philippines |
2020-11-01 |
2020-12-01 |
PHRR201012-003017 |
Phase Not Applicable |
Not yet recruiting |
1 |
1 Month |
|
Gleno Lon Q. Llamera, Pilar Mynthia B. Vicente, Shera Elefante |
2020-10-27 |
| VTE-COVID-19: Non-invasive Prognostication of COVID-19 Patients by Use of Biomarkers in Exhaled Breath Condensate |
Coronavirus disease 19 infection, Lung injury, Respiratory insufficiency |
exhaled breath condensate analysis alone, metabolomics analysis alone, proteomics analysis alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Aalborg Universitetshospital |
Aarhus University Hospital Skejby |
Denmark |
2020-09-19 |
2021-10-01 |
ILG-VTE-COVID-19-2020, N-20200069, NCT04598620, VTE-COVID-19 |
Phase Not Applicable |
Recruiting |
2 |
12 Months |
50 |
Inger L Gade, MD, PhD, Lise T Elkjær |
2020-11-02 |
| Cytokine Storm Among Bangladeshi Patients With COVID-19 |
Coronavirus disease 19 infection, Inflammatory disease |
biological sampling alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry |
International Centre For Diarrhoeal Disease Research, Bangladesh |
|
Bangladesh |
2020-10-31 |
2021-06-30 |
20084, ICDDR,B, NCT04598334 |
Phase Not Applicable |
Not yet recruiting |
1 |
8 Months |
75 |
Mohammod J Chisti, MBBS, PhD, Mohammod J Chisti, MBBS,PhD, Monira Sarmin, Monira Sarmin, MBBS, Monira Sarmin, MBBS, MCPS, Tahmeed Ahmed, MBBS, PhD |
2020-10-30 |
| Safety of Sofosbuvir/Daclatasvir in outpatients with COVID-19 |
Coronavirus disease 19 infection |
Sovodak, Fanavaran Rojan Mohaghegh Daru Co alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Tehran University of Medical Sciences |
International Treatment Preparedness Coalition |
Iran |
2020-10-24 |
|
IR.TUMS.DDRI.REC.1399.024, IRCT20200128046294N3 |
Phase 1/Phase 2 Clinical |
Recruiting |
1 |
|
50 |
Anahita Sadeghi, Neda Alijani, Shahin Merat |
2020-10-28 |
| GlobalSurg-CovidSurg Week: Batangas Medical Center data |
Coronavirus disease 19 infection |
|
|
|
Batangas Medical Center |
|
Philippines |
2020-10-12 |
2021-04-12 |
PHRR201014-003031 |
Phase Not Applicable |
Not yet recruiting |
1 |
6 Months |
|
Amabelle A. Moreno, MD |
2020-11-05 |
| Evaluation of the combination Ivermectin and Azithromycin as treatment in outpatients with COVID-19. Controlled clinical trial |
Coronavirus disease 19 infection |
ivermectin alone, azithromycin plus ivermectin |
Chloride channel modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
National Institute of Respiratory Diseases, Mexico |
|
Mexico |
2020-11-03 |
|
C29-20 |
Phase 2 Clinical |
Status not specified |
1 |
|
306 |
Arnoldo Aquino |
2020-10-28 |
| AcNT-COVID19: Immune Responses to COVID-19; Isolation of Neutralizing Antibodies for Therapeutics and Vaccine |
Coronavirus disease 19 infection |
Blood sampling alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital, Grenoble |
Commissariat a l`Energie Atomique |
France |
2020-04-30 |
2021-09-30 |
2020-A00904-35, 38RC20.132, AcNT-COVID19, NCT04596098 |
Phase Not Applicable |
Recruiting |
2 |
17 Months |
120 |
Benjamin NEMOZ, PHD, Djamila DURIN, engineer, Pascal POIGNARD, PHD, Pierre AUDOIN, engineer |
2020-10-27 |
| Antiviral Activity and Safety of Remdesivir in Bangladeshi Patients With Severe Coronavirus Disease (COVID-19) |
Coronavirus disease 19 infection, Respiratory distress syndrome |
remdesivir alone, standard of care alone |
COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Beximco Pharmaceuticals Ltd |
|
Bangladesh |
2020-09-04 |
2021-01-31 |
BEX-06001, NCT04596839 |
Phase 2 Clinical |
Recruiting |
1 |
4 Months |
60 |
Dr. Md. Alimur Reza, Dr. Md. Alimur Reza, MBBS, MPH, Major General Md. Azizul Islam, Major General Md. Azizul Islam, MBBS, FCPS |
2020-10-28 |
| CAPTURE-2: Research and Evaluation of LumiraDx SARS-CoV-2 (COVID-19) Point of Care Ab Test |
Coronavirus disease 19 infection |
LumiraDx alone, SARS-CoV-2 Ab test alone |
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
LumiraDx UK Ltd |
|
US |
2020-08-20 |
2022-12-31 |
CAPTURE-2, NCT04597047, S-CLIN-PROT-0031 |
Phase Not Applicable |
Recruiting |
4 |
28 Months |
200 |
David Craig, Matthew Morgan, Melanie Hoppers, Vicki Kalen, William Simon |
2020-10-28 |
| NanoDxCoV19: Exploration of Feasability of Blood and Saliva Proteomic Analysis Through Harvesting by Silica Matrix |
Coronavirus disease 19 infection, Respiratory tract infection |
proteomic analysis alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital, Grenoble |
|
France |
2020-10-15 |
2021-12-31 |
38RC20.289, NCT04597216, NanoDxCoV19 |
Phase Not Applicable |
Recruiting |
1 |
14 Months |
200 |
olivier EPAULARD |
2020-10-28 |
| NICOVID-REA: Evaluation of the Efficacy of Nicotine Patches in SARS-CoV2 (COVID-19) Infection in Intensive Care Unit Patients |
Coronavirus disease 19 infection |
nicotine alone |
Nicotinic acetylcholine receptor agonist |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Assistance Publique Hopitaux de Paris |
|
France |
2020-11-30 |
2021-11-30 |
2020-003723-42, APHP200537, NCT04598594, NICOVID-REA |
Phase 3 Clinical |
Recruiting |
3 |
12 Months |
220 |
Alain COMBES, MD, Alexandre DEMOULE, MD, Guylaine LABRO, MD, Sophie DEMERET, MD |
2020-11-17 |
| Expanded Access Study of Exebacase in COVID-19 Patients With Persistent MRSA Bacteremia |
Coronavirus disease 19 infection, Endocarditis, MRSA infection |
antistaphylococcal antibiotic therapy alone, exebacase alone |
Hydrolase stimulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
ContraFect Corp |
|
US |
2020-10-26 |
|
CF-301-107, NCT04597242 |
Phase Not Applicable |
Recruiting |
1 |
|
|
Medical Director, ContraFect |
2020-10-28 |
| Schools Transmission Study (COVID-19 and Scarlet Fever) |
Coronavirus disease 19 infection, Group A Streptococcus infection |
biological sampling alone |
|
Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) |
Imperial College London |
Action Medical Research, National Institute for Health Research (NIHR) |
UK |
2017-09-01 |
2025-03-31 |
CPMS 37059, IRAS 225006, ISRCTN13773960 |
Phase Not Applicable |
Recruiting |
1 |
91 Months |
344 |
Mrs Kerri Hill-Cawthorne, Prof Sriskandan |
2020-10-28 |
| A study to assess safety and efficacy UNI-91103 in patients affected with covid-19 |
Coronavirus disease 19 infection |
UNI-91103 alone |
|
Healthy volunteers accepted |
UNION therapeutics |
|
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
44 |
|
2020-10-26 |
| Evaluation of the Possible Vertical Transmission of SARS-CoV-2 Through Study of Amniotic Fluid and Chorionic Villi of Affected Pregnant Women for the COVID-19 |
Coronavirus disease 19 infection |
|
|
Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Fundacio Institut De Recerca De L'Hospital De La Santa Creu I Sant Pau |
|
Spain |
2020-08-08 |
2022-01-23 |
IIBSP-COV-2020-59, NCT04598347 |
Phase Not Applicable |
Recruiting |
1 |
17 Months |
225 |
Obdulia Alejos Abad, PhD, MD, Obdulia Alejos, MD |
2020-10-28 |
| A prospective study to evaluate the accuracy of Cue COVID-19 Test in the diagnosis of COVID-19 infection |
Coronavirus disease 19 infection |
Cue COVID-19 Test alone |
|
|
Mayo Clinic Foundation |
|
|
|
|
|
Phase Not Applicable |
Status not specified |
0 |
|
|
|
2020-10-26 |
| A pivotal, phase III study of plitidepsin in patients with COVID-19, who require hospitalization |
Coronavirus disease 19 infection |
plitidepsin alone |
Elongation factor 1 alpha 2 modulator, VEGF-1 receptor modulator |
|
PharmaMar SA |
|
|
|
|
|
Phase 3 Clinical |
Planned |
0 |
|
|
|
2020-10-26 |
| A study of association of chest X-ray with clinical severity in hospitalized COVID-19 patients |
Coronavirus disease 19 infection, Hypoxia, Respiratory distress syndrome |
chest X-ray alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kasturba hospital |
|
India |
2020-10-31 |
|
CTRI/2020/10/028525 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
300 |
Nandakrishna B |
2020-10-29 |
| A phase III clinical trial of AT-527 to explore the potential use in patients outside of the hospital setting |
Coronavirus disease 19 infection |
AT-527 alone |
Hepatitis C virus NS5B polymerase inhibitor |
|
Atea Pharmaceuticals Inc, Roche Holding AG |
|
|
2021-03-31 |
|
|
Phase 3 Clinical |
Planned |
0 |
|
|
|
2020-10-27 |
| Hematological and biochemical abnormalities parameters in the severity of COVID-19 |
Coronavirus disease 19 infection |
tocilizumab alone |
|
Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Shree Krishna Hospital, pramukhswami medical college |
|
India |
2020-10-30 |
|
CTRI/2020/10/028523 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
200 |
Dr Abdulrahman Amer, Dr Hitesh Shah |
2020-10-27 |
| COSEVAST study: To study the relationship of COVID-19 severity with blood vessels |
Cardiovascular disease, Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
All India Institute of Medical Sciences Patna |
|
India |
2020-10-26 |
|
COSEVAST study, CTRI/2020/10/028489 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
75 |
Neeraj Kumar, Sanjeev Kumar |
2020-10-29 |
| RISEUP-PPD-COVID-19: Impact of COVID-19 Pandemic in Perinatal Mental Health |
Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder, Psychiatric disorder |
|
|
Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Universidade do Minho |
Bar-Ilan University, European University Cyprus, Havre Hospital, Instituto Presbiteriano Mackenzie, Instituto de Investigacion Biomedica de Malaga, Instituto de Saúde Pública da Universidade do Porto (ISPUP), King's College London, Kırklareli University, Mount Carmel Health System, Universidad Nacional De Educación A Distancia (UNED), Universidad de Huelva, Universidade Católica Portuguesa - Ucp, University of Athens, University of Coimbra, University of Malta, University of Sofia |
Israel, France, UK, Turkey, Brazil, Cyprus, Portugal, Bulgaria, Spain, Malta, Chile, Greece, Albania |
2020-06-15 |
2021-06-15 |
NCT04595123, RISEUP-PPD-COVID-19, RISEUP-PPD-COVID-19 |
Phase Not Applicable |
Recruiting |
13 |
12 Months |
3900 |
Ana Mesquita, PhD, Ana Rita Carlos, Andry Christoforou, PhD, Angelique Picard, PhD, Camellia Hancheva, PhD, Claire Wilson, PhD, Eleni Vousoura, PhD, Emma Motrico, PhD, Erilda Ajaz, PhD, Ethel Felice, Dr, Pelin Dikmen-Yildiz, PhD, Rena Bina, PhD, Sandra M. Saldivia, PhD, Sara Dominguez, PhD, Vera Mateus, PhD |
2020-11-06 |
| The impact of COVID-19 pandemic on colorectal cancer therapy |
Colorectal tumor, Coronavirus disease 19 infection |
|
|
Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Uji-Tokushukai Medical Center |
|
Japan |
2020-08-15 |
|
UMIN000042211 |
Phase Not Applicable |
No longer recruiting |
1 |
|
123 |
Mizuno Rei |
2020-11-06 |
| NETSCOV TRIAL: Role of blood cellular mechanism in severity of COVID-19 |
Coronavirus disease 19 infection |
|
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
All India Institute of Medical Sciences Patna |
|
India |
2020-10-26 |
|
CTRI/2020/10/028488, NETSCOV TRIAL |
Phase Not Applicable |
Not yet recruiting |
1 |
|
60 |
Abhyuday Kumar |
2020-10-28 |
| COVIDCOLLECT: Relationship Between Biological Profiles and Clinical Evolutions Within the Same Cluster COVID-19 |
Coronavirus disease 19 infection |
RT-PCR alone |
|
Healthy volunteers accepted |
University Hospital Clermont-Ferrand |
|
France |
2020-11-30 |
2022-02-28 |
2020-A02381-38, COVIDCOLLECT, NCT04597736, RBPH 2020 HENQUELL |
Phase Not Applicable |
Not yet recruiting |
1 |
15 Months |
100 |
Cécile Henquell, Céclie Henquell, Etienne Merlin, Lise LACLAUTRE, Lise Laclautre, Magali Vidal, Marc Berger, Olivier Lesens |
2020-10-30 |
| CEMS: To Study the safety of remdesivir in COVID-19 Patients |
Coronavirus disease 19 infection |
remdesivir alone |
COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator |
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
All India Institute of Medical Sciences Patna |
|
India |
2020-10-30 |
|
CEMS, CTRI/2020/10/028487 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
100 |
Dr Aakanksha Priya, Dr Shruti Singh |
2020-10-27 |
| CONSERVE-HCW: Changes in Seroprevalence and Wellness Over Time in Healthcare Workers |
Coronavirus disease 19 infection |
bbott Architect SARS-CoV-2 IgG assay alone |
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
St. Joseph's Hospital and Medical Center |
Chandler Regional Medical Center, Dignity Health, Mercy Gilbert Medical Center |
US |
2020-06-10 |
2021-12-30 |
20-510-157-66-21, CONSERVE-HCW, NCT04595175 |
Phase Not Applicable |
Recruiting |
1 |
18 Months |
2000 |
Andrea B. Garcia, MBA, Andrea Garcia, MBA, Brian Tiffany, Brian Tiffany, MD, PhD, Jennine Zumbuhl, RN, MSHA |
2020-10-28 |
| COVID-RT-01: Low Dose Radiation Therapy for Severe-Acute-Respiratory-Syndrome-Coronavirus-2 (SARS-CoV-2), COVID-19 |
Coronavirus disease 19 infection |
low dose radiation therapy (1 Gray) alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Hospital Basel |
|
Switzerland |
2020-11-02 |
2021-11-30 |
2020-02047QU20PAPACHRISTOFILOU, COVID-RT-01, NCT04598581 |
Phase Not Applicable |
Recruiting |
1 |
12 Months |
22 |
Alexandros Papachristofilou, Dr. med., Martin Siegemund, Prof. Dr. med., Tobias Finazzi, Dr. med. |
2020-11-05 |
| LungMechCoV-19: Assessment of Lung Mechanics in COVID-19 Acute Respiratory Distress Syndrome |
Coronavirus disease 19 infection, Respiratory failure |
Impedance tomography alone, indirect calorimetry alone, right-heart catheterization alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University of Zurich |
|
|
2020-10-20 |
2021-12-31 |
2020-01999, LungMechCoV-19, NCT04597853 |
Phase Not Applicable |
Not yet recruiting |
0 |
14 Months |
25 |
Philipp K Buehler, MD |
2020-10-28 |
| FIPPS: Trial of financial incentives for preventing postpartum return to smoking |
Coronavirus disease 19 infection, Nicotine dependence |
financial incentive alone |
|
Female, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
University Of Stirling |
Greater Manchester Combined Authority |
UK |
2018-02-01 |
2022-11-30 |
FIPPS, ISRCTN55218215, VERSION 6.0 |
Phase Not Applicable |
Recruiting |
5 |
58 Months |
900 |
Prof Ussher |
2020-11-10 |
| Challenges faced by PG students in conducting research |
Coronavirus disease 19 infection |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Kasturba Medical College and Hospital |
|
India |
2020-10-26 |
|
CTRI/2020/10/028520 |
Phase Not Applicable |
Not yet recruiting |
1 |
|
800 |
Divya Karanth |
2020-10-27 |
| Treatment of SARS-CoV-2 Virus Disease (COVID-19) in Humans With Hemopurifier Device |
Acute lung injury, Coronavirus disease 19 infection, Multiple organ failure, Respiratory distress syndrome, Respiratory failure, Septic shock |
Hemopurifier alone, arteriovenous fistula treatment alone, double-lumen hemodialysis catheter alone, extracorporeal therapy alone, graft treatment alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Aethlon Medical Inc |
|
US |
2020-10-31 |
2021-08-31 |
AEMD-2020-02, NCT04595903 |
Phase Not Applicable |
Not yet recruiting |
2 |
10 Months |
40 |
Lisa Boswell, Timothy C Rodell, MD, Usman Shah, MD |
2020-10-31 |
| A clinical study to assess AZD-7442 in the treatment of subjects with COVID-19 |
Coronavirus disease 19 infection |
AZD-7442 alone |
COVID19 Spike glycoprotein inhibitor |
|
AstraZeneca plc |
Biomedical Advanced Research and Development Authority (BARDA) |
|
|
|
|
Phase Not Applicable |
Planned |
0 |
|
4000 |
|
2020-10-23 |
| Impact of Covid-19 on mental health among health care workers |
Coronavirus disease 19 infection, Psychiatric disorder |
|
|
Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) |
Indira Gandhi Medical College |
|
India |
2020-12-01 |
|
CTRI/2020/10/028524 |
Phase 3 Clinical |
Not yet recruiting |
1 |
|
632 |
Shabnum Thakur |
2020-10-28 |
| Yoga for COVID-19 Patients with mild symptoms |
Coronavirus disease 19 infection, Respiratory tract infection |
Yoga modules intervention alone |
|
Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) |
Mahatma Gandhi Memorial Medical College, Indore, Swami Vivekananda Yoga Anusandhana Samsthana Svyasa |
|
India |
2020-11-02 |
|
CTRI/2020/10/028486 |
Phase 1 Clinical |
Not yet recruiting |
1 |
|
50 |
Dr Satyapriya Maharana, Pragya Jain Shrimal |
2020-10-27 |