Last updated: Nov 29, 2020 - 02:00 GMT

Title Indication Intervention Actions PatientSelection Sponsor Collaborator Country StartDate EndDate Identifiers Phase Recruitment Status Sites Trial Duration Enrollment Count Contacts LastChanged
Ampligen in Chronic Fatigue Syndrome Chronic fatigue syndrome, Coronavirus disease 19 infection rintatolimod alone 2,5-Oligoadenylate synthetase stimulator, Interferon type I receptor agonist, Ribonuclease stimulator, TLR-3 agonist Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) AIM ImmunoTech Inc US AMP 511, NCT00215813 Phase 3 Clinical Recruiting 2 Ann Marie Coverly, Charles Lapp, MD, Charles W. Lapp, M.D., Daniel Peterson, M.D., Daniel Peterson, MD, Diane Young 2020-10-27
Eye Diseases associated with COVID-19 Choroid disease, Coronavirus disease 19 infection, Retinopathy bedside fundus examination alone, ophthalmoscopy alone, optical coherence tomography alone, optical coherence tomography angiography alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Lilavati Hospital and Research Center India 2020-11-30 CTRI/2020/11/029393 Phase Not Applicable Not yet recruiting 0 30 Dr Salil Mehta 2020-11-27
A study of clinical profile of children with COVID-19 Infection admitted at tertiary care hospital Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs) Smt. NHL Municipal Medical College India 2020-11-28 CTRI/2020/11/029390 Phase Not Applicable Not yet recruiting 0 200 DR Sweety Patel 2020-11-27
Virtual Enhanced Lifestyle for Metabolic Syndrome (ELM) Proof-of-Concept Study Coronavirus disease 19 infection, Metabolic syndrome X virtual enhanced lifestyle for metabolic syndrome program alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rush University Medical Center Geisinger Clinic, Rochester Institute Of Technology, University of Colorado, University of Missouri US 2020-08-01 2021-03-30 20061108, NCT04637477 Phase Not Applicable No longer recruiting 0 7 Months 10 Lynda Powell, PhD 2020-11-27
Phase II, Multi-Site, Randomized, Placebo-Controlled, Double-Blind, Single-Dose Study of TY-027 for Early Treatment of COVID-19 Coronavirus disease 19 infection TY-027, Tychan alone Tychan Pte Ltd Singapore SCT-201 Phase 2 Clinical Status not specified 0 Dr Jenny Low 2020-11-27
XACT: Factor Xa Inhibitor Versus Standard of Care Heparin in Hospitalized Patients With COVID-19 Coronavirus disease 19 infection rivaroxaban alone Factor Xa antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) US 2020-12-01 2021-07-31 2020-001708-41, NCT04640181, XACT Phase 2 Clinical Not yet recruiting 0 8 Months 150 Edward Chafizadeh, MD, Matt Cowperthwaite, PhD, Theresa Pham, MD 2020-11-27
Pirdal Nasal Spray in preventing symptomatic manifestation of disease in COVID-19 proven cases Coronavirus disease 19 infection, Respiratory distress syndrome Covispray (Vitro-Bio Sarl) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Mudra Clincare, Vitro-Bio Sarl India 2020-11-27 CTRI/2020/11/029388, PIR/OBS/2020, Version No.: 4.0 Phase 2 Clinical Not yet recruiting 0 200 Dr S Sadgune, Dr Uma Mulay 2020-11-27
Evaluation of the efficacy and safety of bromhexine administration in COVID-19 Coronavirus disease 19 infection Variable regimens including bromhexine (Tolid Daru Company) , interferon beta-1a follow-on biologic (subcutaneous), CinnaGen , lopinavir + ritonavir (Hetero Labs Limited) Interferon beta ligand Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shaheed Beheshti Medical University Iran 2020-07-10 IR.SBMU.NRITLD.REC.1399.142, IRCT20151227025726N24 Phase 2 Clinical No longer recruiting 1 100 Afshin Zarghi, Farzaneh Dastan, Payam Tabarsi 2020-11-27
A phase II clinical study to assess Persavita's experimental natural health product in the treatment of patients with COVID-19 Coronavirus disease 19 infection natural health product alone Persavita Ltd Canada Phase Not Applicable Planned 1 Dr Piraee 2020-11-27
Effect of cupping on respiratory symptoms of COVID-19 Coronavirus disease 19 infection, Respiratory disease cupping therapy alone, disposable plastic cup alone, standard medication therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Shaheed Beheshti Medical University Iran 2020-09-08 IR.SBMU.RETECH.REC.1399.563, IRCT20200428047229N3 Phase 3 Clinical Recruiting 1 72 Dr. Rasool Choopani, Hanieh Tahermohammadi, Mojgan Tansaz, Zahra Aqanouri 2020-11-27
Formative research for management of serious infections in infants < 2 months of age during COVID pandemic Bacterial infection, Coronavirus disease 19 infection Healthy volunteers accepted Society for Applied Studies World Health Organization India 2020-12-15 CTRI/2020/11/029377 Phase Not Applicable Not yet recruiting 1 70 Nita Bhandari, Sarmila Mazumder 2020-11-27
An online study to assess the disposal of Personal protective equipments at home amid COVID-19 Pandemic in India Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Lady Hardinge Medical College India 2020-05-06 CTRI/2020/11/029376 Phase Not Applicable Completed 1 500 ARCHANA THAKUR 2020-11-27
Pentoxifyliine in COVID-19 Coronavirus disease 19 infection, Viral pneumonia Variable regimens including hydroxychloroquine , interferon beta-1b , lopinavir + ritonavir , pentoxyfylline, Arya company HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mazandaran University of Medical Sciences Iran 2020-11-10 IR.MAZUMS.REC.1399.744, IRCT20190804044429N4 Phase 2/Phase 3 Clinical Recruiting 1 60 Majid Saeedi, Monireh Ghazaeian 2020-11-27
A clinical study to compare high-flow nasal oxygen and non-invasive ventilation in patients with COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory failure high-flow nasal cannula therapy alone, non-invasive ventilation alone, oxygen alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) BLDE University Sri B. M. Patil Medical College India 2020-11-25 CTRI/2020/11/029356 Phase 2 Clinical Not yet recruiting 0 82 Dr Pratibha S D 2020-11-27
Assessing the knowledge and precautions taken by dentists and dental auxiliaries (operating, non-operating) in dental office during the pandemic of Corona virus (COVID-19) Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Manipal College of Dental Sciences India 2020-12-01 CTRI/2020/11/029350 Phase 2/Phase 3 Clinical Not yet recruiting 0 108 Dr Deepak Kumar Singhal, Dr Saloni Gupta 2020-11-27
Spectrum of eye infections in COVID-19 affected individuals Coronavirus disease 19 infection, Endophthalmitis, Panophthalmitis, Uveitis abscess drainage treatment alone, cycloplegic treatment alone, empirical intra-vitreal antibiotic therapy alone, exudation clearance treatment alone, intraocular antibiotic injection therapy alone, non steroidal anti inflammatory drug therapy alone, pars plana vitrectomy alone, silicone oil based retina attachment alone, steroid therapy alone, systemic broad spectrum antibiotic therapy alone, topical broad spectrum antibiotic therapy alone, vitreous biopsy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) L V Prasad Eye Institute India 2020-11-26 CTRI/2020/11/029346 Phase Not Applicable Not yet recruiting 0 20 Dr Sameera Nayak 2020-11-27
PCOVID: Clarithromycin in post Covid 19 parenchymal organizing pneumonia Coronavirus disease 19 infection, Respiratory disease, Viral pneumonia anti-tussive medication therapy alone, bronchodilator therapy alone, clarithromycin alone, mucolytics therapy alone, oral anti-fibrotic therapy alone, oral corticosteroid therapy alone, supplementary micronutrient therapy alone, clarithromycin plus oxygen Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Sri Ramachandra Hospital, Chennai India 2020-11-25 CTRI/2020/11/029305, PCOVID Phase 2 Clinical Not yet recruiting 0 120 Irfan Ismail Ayub 2020-11-27
The Efficacy and Safety of SCTA-01 in Hospitalized Patients With Severe COVID-19 Coronavirus disease 19 infection Best supportive care alone, SCTA-01 alone COVID19 Spike glycoprotein inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sinocelltech Ltd 2021-02-10 2021-10-10 NCT04644185, SCTA01-B301 Phase 2/Phase 3 Clinical Not yet recruiting 0 8 Months 795 Ji Qi, PhD, Zhanghua Lan, PhD 2020-11-27
Effectiveness of Pulmonary Rehabilitation Program in Patients With SARS-CoV-2 Pneumonia Anxiety disorder, Coronavirus disease 19 infection, Respiratory distress syndrome, Respiratory tract infection, Viral pneumonia alternate breathing alone, diaphragmatic breathing alone, early-mobilization and progressive ambulation alone, instructional exercise videos alone, joint ROM exercise alone, peripheral muscle strengthening exercises alone, pulmonary Rehabilitation program alone, pursed-lip breathing alone, respiratory muscle exercises alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sisli Etfal Hospital Turkey 2020-06-30 2021-01-31 2857, NCT04642040 Phase Not Applicable Recruiting 1 7 Months 100 Ali Sahillioglu, MD, Enes Efe Is, MD 2020-11-27
Comparative Effectiveness of IIMR Versus CDSMP Bipolar disorder, Cardiac failure, Cardiovascular disease, Chronic obstructive pulmonary disease, Coronavirus disease 19 infection, Depression, Diabetes mellitus, Drug dependence, Hyperlipidemia, Hypertension, Obesity, Respiratory disease, Schizoaffective disorder, Schizophrenia Integrated Illness Management and Recovery alone, Stanford Chronic Disease Self-Management Program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dartmouth-Hitchcock Medical Center Patient Centered Outcome Research Institute US 2019-09-02 2024-03-31 D19103 31245, NCT03966872 Phase Not Applicable No longer recruiting 2 54 Months 600 Sarah Pratt 2020-11-27
Preoperative Covid-19 Screening In Otorhinolaryngolagy, Head And Neck Elective Surgery Coronavirus disease 19 infection, Surgical procedure Otorhinolaryngolagy alone Hospital Ampang Malaysia 2020-11-26 2020-12-31 57395, NMRR-20-2530-57395 Phase Not Applicable Status not specified 1 1 Month Dr NOR AZIRAH BINTI SALAHUDDIN 2020-11-27
The Role of Hemoperfusion as a Countermeasure for Cytokine Storm in COVID-19 Patients Admitted in a Public Tertiary Hospital in Davao City Coronavirus disease 19 infection Southern Philippines Medical Center Philippines 2020-03-01 PHRR201120-003164 Phase Not Applicable Not yet recruiting 1 Nian Joy T. Ibot, MD 2020-11-27
Development and Validation of Clinical Scoring for Predicting In-Hospital 30-day Mortality Among COVID-19 Patients in University of the Philippines – Philippine General Hospital: A Retrospective, Cohort Study Coronavirus disease 19 infection Philippine General Hospital Philippines 2020-08-10 2020-11-10 PHRR201120-003161 Phase Not Applicable No longer recruiting 1 3 Months Anna Flor Malundo, MD, Dr. Regina P. Berba MD, Karla Kristel A. Banares, MD, Karla Kristel Banares, Maria Sonia Salamat, MD, Marissa M. Alejandria, MD 2020-11-27
Tele-monitoring of COVID-19 Survivors for Long-Term Impacts Coronavirus disease 19 infection Custom-designed miniaturized monitoring system alone, Tele-monitoring alone, video-conferencing sessions alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Manitoba Function Four Ltd 2020-12-01 2021-11-01 B2020:114 (HS24395), NCT04644341 Phase Not Applicable Not yet recruiting 0 11 Months 20 Zahra Moussavi, Ph.D. 2020-11-26
Characteristics of novel coronavirus pneumonia (COVID-19) patients with mild nucleic acid in hospital for over 30 days Coronavirus disease 19 infection, Viral pneumonia Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) People's Hospital of Shapingba District, Chongqing City Chongqing Science and Technology Commission China 2020-09-30 2021-08-31 ChiCTR2000040179 Phase Not Applicable Not yet recruiting 1 11 Months 170 Huang Zi-Yang 2020-11-27
A large-scale, placebo-controlled, phase II/III clinical trial of AG-0301-COVID19 for the prevention of coronavirus infection disease (COVID-19) Coronavirus disease 19 infection AG-0301-COVID19 alone Healthy volunteers accepted AnGes MG Inc 2020-11-30 2022-03-31 Phase 2/Phase 3 Clinical Recruiting 0 16 Months 500 2020-11-27
Safety and Pharmacokinetics of a Novel Niclosamide Solution in Combination With Camostat Coronavirus disease 19 infection niclosamide alone, camostat mesylate plus niclosamide Serine protease inhibitor, Transmembrane serine protease 2 inhibitor, Trypsin inhibitor Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Charite Research Organisation Bayer AG Germany 2020-11-02 2021-05-31 201767, NCT04644705, NIC-002 Phase 1 Clinical Recruiting 1 6 Months 28 Frank D Wagner, Prof. Dr. med., Maximilian Posch, Dr. med. 2020-11-26
NeuroCovid: WHO - Neurological Abnormalities in SARS-CoV-2 ICU Patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Clermont-Ferrand France 2020-10-13 2021-08-13 NCT04643548, NEUROCOVID-RNI 2020 GODET, NeuroCovid Phase Not Applicable Recruiting 1 10 Months 20 Benjamin Rieu, Lise Laclautre, Thomas Godet 2020-11-27
A phase II study to evaluate safety and effectiveness of IND-02 capsules in patients who are hospitalized SARS-CoV2 positive patients with mild to moderate COVID-19 at COVID management centers offering ayurvedic care Coronavirus disease 19 infection IND-02 alone, standard of care treatment alone ApoB editing catalytic polypeptide 3G modulator, HIV gp120 protein modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) IQVIA RDS (India) Pvt Ltd, Indus Biotech Pvt Ltd India 2020-11-30 CTRI/2020/11/029328, IND02-ORAL-COVID-19 Version 1.0 Phase 2 Clinical Not yet recruiting 5 118 Dr Ajay Javeri, Dr Amlendu Yadav, Dr Amol Laxmanrao Dange, Dr Jaya Prakash Appajigol, Dr Shrikant Deshpande, Suneela Thatte 2020-11-26
Differential Leukocyte Count and Covid-19 Diagnosis Coronavirus disease 19 infection CLDC algorithm alone, Differential leukocyte count (CLDC) device alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Istituto Neurologico Mediterraneo NEUROMED Italy 2020-12-31 2021-05-31 DEP_042020, NCT04643860 Phase Not Applicable Not yet recruiting 2 5 Months 1000 Licia Iacoviello 2020-11-26
Mask Adhesive Institutional Study Coronavirus disease 19 infection, Respiratory failure AF531 non-invasive ventilation mask (Philips) alone, PerformaTrak non-invasive ventilation mask (Philips) alone, mask adhesive (Philips) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Royal Philips Electronics US 2020-11-17 2020-12-17 NCT04644276, SRCHRCMASK ADHESIVE 2020_11130 Phase Not Applicable Not yet recruiting 1 1 Month 30 Robert Doekel, Wes Booth 2020-11-26
Telerehabilitation Following Meniscectomy Coronavirus disease 19 infection, Knee injury knee exercises alone, meniscectomy alone, proprioception and balance training alone, telerehabilitation therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) NYU Langone Health US 2020-12-01 2022-12-01 20-01584, NCT04644640 Phase Not Applicable Not yet recruiting 1 24 Months 60 Eoghan Hurley, MB, BCh, MCh, Eric Strauss, MD, Guillem Gonzalez-Lomas, MD, Kirk Campbell, MD, Laith Jazrawi, MD, Michael Alaia, MD 2020-11-26
Apprehensions and challenges faced by dentists during Covid-19 pandemic Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Manipal College of Dental Sciences India 2020-12-02 CTRI/2020/11/029335 Phase Not Applicable Not yet recruiting 1 189 Dr Sunitha Carnelio, Muskaan Chichra 2020-11-27
Improving Thinking in Everyday Life After Covid-19 Cognitive disorder, Coronavirus disease 19 infection instrumental activities of daily living shaping alone, speed of processing training alone, transfer package alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Alabama at Birmingham US 2020-11-01 2024-11-30 IRB-300002814C, NCT04644172 Phase 1/Phase 2 Clinical Recruiting 1 49 Months 40 Edward Taub, Edward Taub, Ph.D., Staci McKay 2020-11-27
Brief Video Interventions for Depression Coronavirus disease 19 infection, Depression video-based intervention on behavioral emotion regulation skill alone, video-based intervention on cognitive emotion regulation skill alone, video-based intervention on interpersonal emotion regulation skill alone, video-based intervention on three emotion regulation skill alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ohio State University US 2020-11-30 2020-11-30 2020B0326, NCT04643964 Phase Not Applicable Recruiting 1 501 Daniel R Strunk, Ph.D., Graham C Bartels, B.S., Jennifer S Cheavens, PhD, Robert J Zhou, B.A. 2020-11-27
Effects of a Biomechanical-based Tai Chi Program on Gait and Posture in People With Parkinson's Disease: Study Protocol for a Randomized, Controlled Trial Coronavirus disease 19 infection, Parkinsons disease Tai Chi training alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Ottawa Canada 2021-01-31 2021-12-31 H-01-19-2284, NCT04644367 Phase Not Applicable Not yet recruiting 1 11 Months 40 Jing Xian Li, PhD., Nok-Yeung Law, Nok-Yeung Law, M.Sc. 2020-11-26
Using Travelan to Boost Immune Response in Vitro to COVID-19 Coronavirus disease 19 infection Travelan alone Healthy volunteers accepted, Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hadassah Medical Organization Israel 2020-11-01 2020-12-31 HEALTHYTRAVELANCOV19- HMO-CTIL, NCT04643561 Phase 1/Phase 2 Clinical No longer recruiting 1 2 Months 5 Assaf Potruch, MD 2020-11-27
The Doctors for Coronavirus Prevention Project Thanksgiving Messaging Campaign Coronavirus disease 19 infection Facebook Ads alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Bureau of Economic Research Inc Harvard University, Massachusetts General Hospital, Massachusetts Institute of Technology, Stanford University, Yale University US 2020-11-14 2021-11-26 2003000118A010, NCT04644328 Phase Not Applicable Not yet recruiting 1 12 Months 20000000 Esther Duflo 2020-11-26
Management of Type 1 Supracondylar Humeral Fractures: A Multicenter, Randomized, Control Trial Coronavirus disease 19 infection, Upper limb fracture long arm soft casting alone Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs) University of British Columbia Lady Cilento Children's Hospital Canada 2021-01-31 2023-01-31 H20-02942, NCT04642807 Phase Not Applicable Not yet recruiting 1 24 Months 52 Anthony Cooper, Anthony Cooper, FRCSC, Harpreet Chhina, MSc 2020-11-27
Convalescent Plasma Transfusion in Severe COVID-19 Patients in Jamaica Coronavirus disease 19 infection convalescent plasma alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of the West Indies Jamaica 2020-12-01 2021-12-01 ECP/195,19/20, NCT04644198 Phase 2 Clinical Not yet recruiting 1 12 Months 30 Gilian G Wharfe, Giliian G Wharfe, MB, BS, DM, Tomlin Paul 2020-11-26
COVID-OISE: Longitudinal Follow-up of a Population Cohort in a French City With High SARS-CoV-2 Circulation in Early 2020 Coronavirus disease 19 infection Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institut Pasteur France 2020-11-13 2023-11-01 2020-060, COVID-OISE, NCT04644159 Phase Not Applicable Recruiting 2 35 Months 2000 Aymar KOFFI, Dr, Bruno HOEN, Pr, Cécile DURU, Dr, Laurie Pinaud, Marie-Noëlle UNGEHEUER,, Sandrine Fernandes Pellerin 2020-11-26
Develop homeopathic Nosodes for Immunity Against COVID 19 Coronavirus disease 19 infection nosode alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Council for Research in Homeopathy Ministry of Ayush, National Cancer Institute, Jhajjar, AIIMS India 2020-12-10 CTRI/2020/11/029399 Phase 1 Clinical Not yet recruiting 1 20 Dr Naval Kumar Verma, Dr Sushma Bhtanagar 2020-11-26
Palliative Care in COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kasturba Medical College and Hospital India 2020-12-07 CTRI/2020/11/029398 Phase Not Applicable Not yet recruiting 1 50 Seema Rajesh Rao 2020-11-26
Changing Trends in Presentation of Trauma Patients during Nationwide lockdown for COVID-19 Coronavirus disease 19 infection, Injury Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) India 2020-12-01 CTRI/2020/11/029297 Phase Not Applicable Not yet recruiting 1 100 Vipul Versi Nandu 2020-11-27
Study to Assess Adverse Events and How Intravenous ABBV-47D11 Moves Through the Body of Adult Participants Hospitalized With Coronavirus Disease 2019 (COVID-19) Coronavirus disease 19 infection, Lower respiratory tract infection ABBV-47D11 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) AbbVie Inc US 2020-11-27 2021-05-01 2020-005203-39, M20-404, NCT04644120 Phase 1 Clinical Not yet recruiting 11 5 Months 24 ABBVIE CALL CENTER, AbbVie Inc. 2020-11-27
Safety of an aerosol having as its active ingredient 8.4% sodium bicarbonate and xylitol 5% when administered to the nasopharynx and oropharynx Coronavirus disease 19 infection, Influenza virus infection Variable regimens including benzalkonium chloride , glycerine , propylene glycol , sodium bicarbonate , xylitol Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Myself Health Check Ltd Welcare Hospital India 2020-12-01 CTRI/2020/11/029396 Phase 2 Clinical Not yet recruiting 1 325 Dr Kshitij Mody, Dr Manoj Parmar, Dr Vidhi Hingu 2020-11-26
Semen Parameters and COVID-19 in Infertile Men Coronavirus disease 19 infection, Male infertility reverse transcriptase polymerase chain reaction test alone, spermiogram analysis alone Male, Young Adults (18-44 yrs) Ankara City Hospital Bilkent Turkey 2020-01-07 2020-10-10 E1-20-1237, NCT04643522 Phase Not Applicable Completed 1 9 Months 21 Erdem Koc 2020-11-26
Precautionary measure during surgical process during COVID-19 pandemic around the globe Coronavirus disease 19 infection FFP-2 mask alone, N-95 mask alone, nasal prongs alone, oxygen therapy alone, suction cannula alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) India 2020-12-01 CTRI/2020/11/029394 Phase Not Applicable Not yet recruiting 1 30 Dr Pradipkumar Raghuvirsinh Atodaria 2020-11-27
Circulatory Coherence in COVID and Non-COVID Patients With Sepsis Coronavirus disease 19 infection, Sepsis microcirculation recording alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Hradec Kralove Czech Republic 2020-02-01 2021-12-31 FNHK_IGS_8144, NCT04644302 Phase Not Applicable Recruiting 1 23 Months 25 David Astapenko, M.D., Pavel Dostal, M.D., Ph.D., MBA, Vladimir Cerny, Vladimir Cerny, prof. 2020-11-27
Anakinra in the Management of COVID-19 Infection: A Randomized, Clinical Trial Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia Standard of care alone, anakinra alone Type I IL-1 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hamad Medical Corp Qatar 2020-10-30 2021-10-30 MRC-05-140, NCT04643678 Phase 2/Phase 3 Clinical Recruiting 1 12 Months 80 Dr. Eman Elmekaty, PharmD 2020-11-27
Iodine treatment Coronavirus infection Coronavirus disease 19 infection iodine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Maxima Medisch Centrum Veldhoven Netherlands 2020-07-14 01-04-2020, 2020-001852-16 Phase 2 Clinical Recruiting 1 224 reumatology department 2020-11-27
PoliCOV: PoliCOV19-Serosurvey Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Bern Blutspendedienst SRK Bern AG Switzerland 2021-01-31 2022-06-30 2020-02650, NCT04643444, PoliCOV Phase Not Applicable Not yet recruiting 1 17 Months 1000 Parham Sendi, MD 2020-11-26
COVIDGEN: Genetic Predisposition to Severe Forms of COVID-19 (SARS-CoV2 Infection) Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hospices Civils De Lyon France 2020-12-01 2021-12-01 69HCL20_1072, COVIDGEN, NCT04644146 Phase Not Applicable Recruiting 1 12 Months 40 Alain CALENDER, MD 2020-11-27
Inflammatory Markers and Hematological Indices in the Prediction of Severity of COVID-19: A Single Center Study in Southern Philippines Coronavirus disease 19 infection Southern Philippines Medical Center Philippines 2020-11-30 2021-04-30 PHRR201117-003152 Phase Not Applicable Not yet recruiting 1 5 Months Meccar Moniem Haradji Elino 2020-11-27
The effect of selenium in patients with COVID-19 Coronavirus disease 19 infection selenium alone Ghoum University of Medical Sciences Qom University of Medical Science Iran 2020-03-20 2020-06-20 IR.MUQ.REC.1398.161, IRCT20160919029870N3 Phase 3 Clinical Completed 1 3 Months 80 Hamed Shafiee 2020-11-27
An interventional study on the assessment of QT interval prolongation under hydroxychloroquine/azithromycin association among inpatients with SARS-CoV-2 lower respiratory tract infection Coronavirus disease 19 infection, Lower respiratory tract infection azithromycin plus hydroxychloroquine Centre Hospitalier Universitaire De Nice Phase 2 Clinical Status not specified 0 73 2020-11-26
Repeat Computed Tomography Simulation among Head and Neck Cancer Patients experiencing Delayed Radiation Therapy in a State Referral Center during the COVID-19 Pandemic Coronavirus disease 19 infection, Head and neck tumor Computed Tomography (CT) simulation alone, external beam radiotherapy alone Philippine General Hospital Philippines 2020-06-18 2020-12-18 PHRR201117-003125 Phase Not Applicable Recruiting 1 6 Months Benedict Crisostomo 2020-11-27
A Phase II/III Study of Sargramostim Coronavirus disease 19 infection, Viral pneumonia NPC-26 alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Japanese Ancestry Nobelpharma Co Ltd Japan 2020-11-24 2021-04-30 NCT04642950, NPC-26-1 Phase 2/Phase 3 Clinical Not yet recruiting 4 5 Months 60 Masaki Taniguchi 2020-11-27
EPIC-19: Application of Convalescent Plasma in the Treatment of SARS CoV-2 Disease (COVID-19) With Evaluation of Therapy Effectiveness Coronavirus disease 19 infection, Respiratory distress syndrome anti SARS-CoV-2 convalescent plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Wroclaw Medical University Medical Research Agency (Agencja Badań Medycznych) Poland 2020-12-01 2022-05-01 2020.ABM.COVID19.0005, EPIC-19, NCT04642014 Phase 2 Clinical Not yet recruiting 1 17 Months 500 Jarocław Dybko, PhD, Siddarth Agrawal, PhD 2020-11-27
PEER MHEALTH: The impact of WASH text messages and environmental cues intervention on hand hygiene practice among healthcare workers in the greater Kampala metropolitan area, Uganda Coronavirus disease 19 infection, Sepsis Glo Germ gel alone, environmental cues intervention alone, mhealth water, sanitation and hygiene text message intervention alone, simple hand washing facility usage alone National Academy of Sciences Uganda 2020-01-01 2021-09-30 8-187, ISRCTN98148144, PEER MHEALTH Phase 2 Clinical Not yet recruiting 1 21 Months 450 Dr Richard Mugambe 2020-11-27
Mortality in Patients With Severe COVID-19 Pneumonia Who Underwent Tracheostomy Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia mechanical ventilation alone, percutaneous tracheostomy alone, surgical tracheostomy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Chile Chile 2020-03-03 2021-11-30 65/20, NCT04642703 Phase Not Applicable Recruiting 1 20 Months 100 Abraham Gajardo, MD, Carlos Romero, MD 2020-11-27
UK-REACH: United Kingdom research study into ethnicity and COVID-19 outcomes in healthcare workers Coronavirus disease 19 infection Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Leicester National Institute for Health Research (NIHR), United Kingdom Research & Innovation UK 2020-08-01 2045-08-01 IRAS 288316, ISRCTN11811602, SPONSOR REFERENCE 0801, UK-REACH Phase Not Applicable Recruiting 1 300 Months 1530180 Dr Claire Garwood, Dr Pareek 2020-11-27
Clinical Trial of the Immunogenicity, Safety, and Efficacy of the Gam-COVID-Vac Vaccine Against COVID-19 in Venezuela Coronavirus disease 19 infection Sputnik V alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Gamalei Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation Collaborator Venezuela 2020-11-30 2021-12-31 01V-GAM-COVID-VAC-2020, NCT04642339 Phase 3 Clinical Not yet recruiting 1 13 Months 2000 Alexis H García Piñero, MD 2020-11-27
A pilot, randomized, controlled trial examining the feasibility, acceptability and preliminary efficacy of an internet-delivered cognitive bias modification to reduce co-occurring social anxiety and alcohol use in young Australians Alcoholism, Anxiety disorder, Coronavirus disease 19 infection, Social phobia Approach Bias Modification alone, Interpretation Bias Modification (IBM) alone, treatment as usual alone Young Adults (18-44 yrs), Oceanic Ancestry University of Sydney Australian Rotary Health, National Health and Medical Research Council Australia 2021-01-04 ACTRN12620001273976, U1111-1252-8422 Phase Not Applicable Not yet recruiting 1 90 Dr Katrina Prior 2020-11-25
AIR: Air for Infant Resuscitation Birth complication, Coronavirus disease 19 infection, Respiratory disease Royal Hospital for Women, University of New South Wales Vietnam, Guatemala, Spain, Australia, Malaysia, India, China, US, Indonesia, Canada, Singapore 2020-12-01 2021-09-01 ACTRN12620001252909, AIR Phase Not Applicable Not yet recruiting 17 9 Months 200 A/Prof Ju-Lee Oei, Mr James Sotiropoulos 2020-11-25
A trial to evaluate aprotinin (inhalation therapy), ChemRar High Tech Center for the treatment of patients with severe COVID-19 Coronavirus disease 19 infection aprotinin (inhalation therapy), ChemRar High Tech Center alone ChemRar High Tech Center Phase Not Applicable Status not specified 0 2020-11-25
A trial to evaluate aprotinin (intravenous), ChemRar High Tech Center for the treatment of patients with moderate COVID-19 Coronavirus disease 19 infection aprotinin (intravenous), ChemRar High Tech Center alone ChemRar High Tech Center Phase Not Applicable Status not specified 0 2020-11-25
A trial to evaluate aprotinin (nasal spray) for the prevention of coronavirus infection Coronavirus disease 19 infection aprotinin (nasal spray) alone ChemRar High Tech Center Phase Not Applicable Status not specified 0 2020-11-25
The Loddon Mallee Healthcare Worker COVID-19 Study Anxiety disorder, Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bendigo Health Care Group, La Trobe University Victorian State Government Australia 2020-11-27 ACTRN12620001269921 Phase Not Applicable Not yet recruiting 1 4000 A/Prof Mark McEvoy, Dr Carol Parker 2020-11-26
Contrast Enhanced Ultrasound in COVID-19 Coronavirus disease 19 infection, Vascular disease contrast-enhanced ultrasound alone, sodium chloride plus sulphur hexafluoride microbubble ultrasound agent, Bracco Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) Childrens Hospital of Philadelphia US 2020-11-30 2022-12-31 20-017501, NCT04640038 Phase 3 Clinical Recruiting 1 25 Months 30 Luis Tierradentro, MD, Misun Hwang, Misun Hwang, MD 2020-11-27
CHAT: Intravenous immunoglobulin rich in neutralising antibodies to SARS-CoV-2 as a passive immunity modality in healthy individuals at risk of infection with COVID-19: an open-label, active control, Phase I/II Study Coronavirus disease 19 infection hyperimmune IG (HIVIG) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Australia 2020-12-01 2021-10-01 ACTRN12620001249943p, AEG-CTP-01, CHAT, U1111-1261-2497 Phase 1/Phase 2 Clinical Not yet recruiting 2 10 Months 30 A/Prof Roderick Clifton-Bligh, Dr Guy Gavagna 2020-11-26
A study to assess safety and efficacy of COR-101 for the potential use of COVID-19 Coronavirus disease 19 infection anti-SARS-CoV2 antibodies (COVID-19 infection), Corat Therapeutics alone Corat Therapeutics GmbH 2021-01-01 Phase not specified Status not specified 0 2020-11-25
Efficacy and Safety of Ovotransferrin in COVID-19 Patients Coronavirus disease 19 infection, Viral pneumonia ovotransferrin alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone Palermo Italy 2020-12-01 2021-03-30 20201116, NCT04643054 Phase Not Applicable Not yet recruiting 1 3 Months 100 Antonio Cascio, Antonio Cascio, MD, Antonio Cascio, MD, PhD 2020-11-26
Virtual models for delivery of exercise training in Cystic Fibrosis (CF): an evaluation of patient engagement and feasibility Coronavirus disease 19 infection, Cystic fibrosis online exercise classes alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The Prince Charles Hospital Australia 2020-12-31 ACTRN12620001237976p Phase Not Applicable Not yet recruiting 1 24 Miss Kelly Burgess 2020-11-26
COROBIOCHIC: Cardiac Biomarkers and Mortality in Critically Ill Patients With SARS-CoV-2 (COVID-19) Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Montpellier France 2020-02-01 2020-06-30 COROBIOCHIC, NCT04641988, RECHMPL20-0625 Phase Not Applicable Completed 1 5 Months 111 Romaric Larcher, MD, PharmD, MSc 2020-11-26
TBA: Evolution of diaphragm and abdominal muscle thickness in ventilated COVID-19 patients Coronavirus disease 19 infection, Muscle weakness Ultrasound alone, mechanical ventilation alone Amsterdam UMC Netherlands 2020-11-09 2021-01-15 2017.056, NL9053, TBA Phase Not Applicable Recruiting 1 2 Months 40 Mark Haaksma 2020-11-26
Light on COVID-19 Coronavirus disease 19 infection Respiratory physiotherapy alone, conventional treatment alone, infrared LED alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Brazil 2020-10-04 36988320.5.0000.5492, 4.269.568, 4.317.859, CAAE 37010820.0.0000.5492, RBR-2z5t7z, U1111-1261-1981 Phase 1 Clinical Recruiting 1 40 Pâmela Camila Pereira 2020-11-27
A phase Ib, open-label, single-arm, investigator-initiated trial to evaluate the safety and efficacy of motixafortide in the treatment of patients suffering from acute respiratory distress syndrome (ARDS) secondary to COVID-19 and other respiratory viral infections Coronavirus disease 19 infection, Respiratory distress syndrome, Viral respiratory tract infection motixafortide alone CXCR4 chemokine antagonist BioLineRx Ltd Israel 2020-11-18 Phase 1b Clinical Recruiting 1 25 Dr Yasmin Maor 2020-11-25
Analysis of motor response time, electromyography and muscle strength in volunteers from the group at risk for covid-19 submitted to a home exercise protocol: randomized, controlled, clinical trial, cross over Coronavirus disease 19 infection PhysioPlay alone, electromyography alone, home exercise alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Federal University of Alfenas Brazil 2021-04-05 36899320.7.0000.5142, 4.355.736, RBR-2fvw6v, U1111-1257-6957 Phase Not Applicable Not yet recruiting 0 20 Leonardo Cesar Carvalho 2020-11-27
LYMPHO-Cov-2: Clinical and Immunological Evolution of COVID-19 Occurring in a Context of Non-Hodgkin Lymphoma B-cell lymphoma, Coronavirus disease 19 infection, Non-Hodgkin lymphoma monoclonal anti-CD20 antibodies therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Versailles University Hospital France 2020-12-15 2021-09-16 LYMPHO-Cov-2, NCT04641806, P20/21-LYMPHO-COV-2 Phase Not Applicable Not yet recruiting 1 9 Months 120 Caroline BESSONHospital 2020-11-26
BCG-COVID-RCT: BCG to Reduce Absenteeism Among Health Care Workers During the COVID-19 Pandemic (EDCTP) Coronavirus disease 19 infection BCG-Denmark alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Southern Denmark Bandim Health Project, Centro de Investigacao em Saude de Manhica, European and Developing Countries Clinical Trials Partnership, Instituto De Higiene E Medicina Tropical, The University of Cape Verde Guinea-Bissau, Cape Verde, Mozambique 2020-11-30 2022-03-31 BCG-COVID-RCT, BCG-COVID-RCT, NCT04641858 Phase 4 Clinical Not yet recruiting 3 16 Months 1050 Amabélia Rodrigues, MD, PhD, Christine Stabell Benn, Professor, Helio Mucavele, MD, Inês Fronteira, PhD, Isabel Inês Araújo, Professor, Maria da Luz Lima, Pedro Aide, MD, MSc, PhD, Peter Aaby, DMSc 2020-11-26
INNOVATE: Safety, Immunogenicity and Efficacy of INO-4800 for COVID-19 in Healthy Seronegative Adults at High Risk of SARS-CoV-2 Exposure Coronavirus disease 19 infection CELLECTRA 2000 device alone, INO-4800 alone, electroporation alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Inovio Pharmaceuticals Inc US Department of Defense US 2020-11-30 2022-09-30 COVID19-311, INNOVATE, INNOVATE, NCT04642638 Phase 2/Phase 3 Clinical Not yet recruiting 16 22 Months 6578 Barbara Rizzardi, Christopher Chambers, Corey Anderson, Donna DeSantis, Ernie Riffer, Inovio Call Center, Jeffrey Rosen, John Ervin, Louis Saravolatz, Mammen P. Mammen Jr, M.D., FACP, FIDSA, Mark Adams, Melinda Hamer, Michael Jacobs, Olutola Adetona, Pablo Tebas, Patrick Yassini, Principal Investigator Christopher Chambers, Principal Investigator Melinda Hamer, Prinicipal Investigator Barbara Rizzardi, Prinicipal Investigator Corey Anderson, Prinicipal Investigator Donna DeSantis, Prinicipal Investigator Ernie Riffer, Prinicipal Investigator Jeffrey Rosen, Prinicipal Investigator Louis Saravolatz, Prinicipal Investigator Michael Jacobs, Prinicipal Investigator Olutola Adetona, Prinicipal Investigator Patrick Yassini, Prinicipal Investigator Sady A. Alpizar, Prinicipal Investigator Vickie Miller, Program Manager Amanda Bear, Program Manager Barbara Bradshaw, Program Manager Ginger Switzer, Sady A. Alpizar, Vickie Miller 2020-11-27
COVID-19 in Home Healthcare Coronavirus disease 19 infection home health care alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) University Hospital, Linkoeping Sweden 2020-05-02 2020-10-10 HOME HEALTHCARE 2020, NCT04642196 Phase Not Applicable Completed 1 5 Months 155 Lena Nilsson 2020-11-27
Study Investigating the Effects of UVC Beam and Laser Beam Therapy According to Standard Therapy in Patients With Covid-19 Diagnosis Coronavirus disease 19 infection, Dyspnea, Respiratory disease, Viral pneumonia Turkish Beam-Selective UV device (Rd Global Arastirma Gelistirme Saglik Ilac Insaat Yatirimlari AS) alone, anitibiotic therapy alone, antimalarial therapy alone, antiviral therapy alone, ultraviolet C application alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Rd Global Arastirma Gelistirme Saglik Ilac Insaat Yatirimlari Sanayi Ve Ticaret Anonim Sirketi Gazi University Turkey 2020-06-26 2021-05-04 MD2020/001, NCT04642326 Phase Not Applicable No longer recruiting 1 10 Months 50 Hikmet Selcuk Gedik 2020-11-27
Response of patients and chest X-ray improvement after Remdesivir Coronavirus disease 19 infection remdesivir alone COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kasturba Medical College, Kasturba hospital India 2020-12-04 CTRI/2020/11/029266 Phase Not Applicable Not yet recruiting 1 126 Vishal Shanbhag 2020-11-26
A trial to evaluate saliva-based test detect the presence of antibodies to SARS-CoV-2 Coronavirus disease 19 infection saliva-based test alone Johns Hopkins Bloomberg School of Public Health Phase Not Applicable Status not specified 0 2020-11-25
To study the long-term ill effects of COVID-19 infection in old age people Coronavirus disease 19 infection Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sri Ramachandra Institute of Higher Education and Research India 2020-12-01 CTRI/2020/11/029264 Phase Not Applicable Not yet recruiting 1 400 Dr Sathyamurthy 2020-11-26
A Phase III Clinical Trial for SARS-CoV-2 Vaccine, Inactivated (Vero Cell) in Malaysia Coronavirus disease 19 infection SARS-CoV-2 Vaccine, Inactivated (Vero Cell) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Institute of Medical Biology Chinese Academy of Medical Sciences Malaysia 2020-12-01 2022-01-31 20200404, 57143, NMRR-20-2514-57143 Phase 3 Clinical Not yet recruiting 5 14 Months 3000 Cheung Tian Pei, Datuk Dr. Muhammad Radzi Abu Hassan, Doctor DR Yasmin Mohamed Gani, Dr Cheah Wee Kooi, Dr Chua Hock Hin, Dr DAMENTHI NAIR A/P NARAYANAN, Dr Liew Boon Seng, Dr Looi Irene, Dr Yoon Chee Kin, Dr philip rajan 2020-11-26
Vitamin D and Zinc Supplementation for Improving Treatment Outcomes Among COVID-19 Patients in India Coronavirus disease 19 infection Vitamin D3 (cholecalciferol) alone, Zinc (zinc gluconate) alone, Vitamin D3 (cholecalciferol) plus Zinc (zinc gluconate) Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Harvard TH Chan School of Public Health The University Health Network India 2020-12-07 2021-12-31 NCT04641195, VR3- 172649 Phase 3 Clinical Not yet recruiting 2 12 Months 700 Guaray Gupta, MD, Kevin Kain, MD, Wafaie W Fawzi, MBBS, MPH, MS, DrPH, Wafaie W Wafaie, MBBS, MPH, MS, DrPH 2020-11-26
A reasearch study to utilize the AIRx Health platform to monitor COVID-19 outpatients to better understand which patients deteriorate faster and require hospitalization Coronavirus disease 19 infection AIRx Health alone Stanford Medicine US Phase Not Applicable Status not specified 1 2000 2020-11-25
Associated factors for COVID-19 infection in Terengganu Coronavirus disease 19 infection Malaysia 2020-11-20 2020-12-20 57220, NMRR-20-2468-57220, PKDD2020/1 Phase Not Applicable Not yet recruiting 1 1 Month Dr Hafizuddin Bin Awang, Dr. Effah Leiylena Binti Yaacob 2020-11-26
Accuracy of POCUS ultrasound in detecting severity of confirmed symptomatic COVID-19 patients in MTC Coronavirus disease 19 infection point-of-care lung ultrasound alone Sultanah Bahiyah Hospital Malaysia 2020-11-17 2020-12-31 56961, NMRR-20-2480-56961 Phase Not Applicable Status not specified 1 1 Month Dr Fatahul Laham Mohamed, Ong Sheue Fen 2020-11-26
A clinical study on favipiravir in mild to moderate COVID-19 patients Coronavirus disease 19 infection favipiravir alone RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Glenmark Pharmaceuticals Ltd India 2020-11-30 CTRI/2020/11/029263, GPL/CT/2020/007/IV Version 2.0 Phase 4 Clinical Not yet recruiting 3 1200 Dr Saiprasad Patil, Rajesh Gaikwad 2020-11-26
Role of vitamin C in management of COVID 19 Coronavirus disease 19 infection vitamin C alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Medical Sciences Patna India 2020-11-20 CTRI/2020/11/029230 Phase 3 Clinical Not yet recruiting 1 80 DR VIJAY KUMAR 2020-11-26
Characterization of COVID-19 long-term immunity Coronavirus disease 19 infection 6 min walking respiratory function testing alone, serological testing alone, sit-to-stand respiratory function testing alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Bristol Medical Research Council UK 2020-08-01 2021-11-30 CPMS 47414, IRAS 289646, ISRCTN11946807 Phase Not Applicable Recruiting 1 16 Months 250 Dr Lewcock, Prof Timpson 2020-11-26
REGAIN: A randomized trial to assess the effects of physical and mental health rehabilitation for people recovering from COVID-19 Coronavirus disease 19 infection home-based rehabilitation program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospitals Coventry & Warwickshire NHS Trust NIHR Evaluation, Trials and Studies Coordinating Centre (NETSCC) UK 2020-09-01 2022-08-31 CPMS 46819, IRAS 288362, ISRCTN11466448, REGAIN Phase Not Applicable Not yet recruiting 1 24 Months 535 Ms Sharisse Alleyne 2020-11-25
Evaluation of stem cells treatment in Covid-19 patients Coronavirus disease 19 infection Mensenchymal Stem Cells alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Stemcorp Brazil 2020-11-19 4.167.621, A01224210603, CAAE: 32650720.1.0000.0068, RBR-4jh63b Phase 1/Phase 2 Clinical Recruiting 1 30 Eder Zucconi, Mariane Secco, Natassia Vieira Serafini 2020-11-25
TRISTARDS: A Study to Test Whether Different Doses of Alteplase Help People With Severe Breathing Problems Because of COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome alteplase alone, standard of care alone Tissue plasminogen activator stimulator Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Boehringer Ingelheim International GmbH 2020-12-07 2022-06-01 0135-0347, 2020-002913-16, NCT04640194, TRISTARDS Phase 2/Phase 3 Clinical Not yet recruiting 0 17 Months 270 Boehringer Ingelheim 2020-11-25
Dulce: HbA1c Pre and Post-Confinement in Latin American Children With Type 1 Diabetes Coronavirus disease 19 infection, Insulin dependent diabetes Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) Hospital General Puyo Argentina 2020-11-22 2021-04-22 0019, Dulce, NCT04640064 Phase Not Applicable Not yet recruiting 1 5 Months 500 Angela Figueroa Sobrero, MD, Carlos Del Aguila Villar, MD, Diana Gonzalez, MD, Edgar Mora, MD, Edit Scaiola, MD, Fabio Palacios Porta, MD, Franco Giraudo Abarca, MD, Julie Pelicand, MD, Kesia Granela, MD, Nicole Monteverde, MD, Valeria Hirschler 2020-11-26
Effect of the drug indomethacin in the treatment of COVID-19 patients Coronavirus disease 19 infection Standard care alone, indomethacin alone, proton pump inhibitor therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Indian Institute Of Technology Madras India 2020-07-27 2021-01-01 CR/20-21/ED/208/ALUM/002553​, ISRCTN11970082 Phase 2 Clinical Recruiting 2 5 Months 250 Dr Rajan Ravichandran, Prof KrishnaKumar 2020-11-25
Prognostic value of simple computer-aided quantitative chest CT analysis among known cases of COVID-19 pneumonia in Philippine General Hospital Coronavirus disease 19 infection, Viral pneumonia chest CT analysis alone Philippine General Hospital, University of the Philippines Philippines 2020-12-01 2021-03-01 PHRR201120-003166 Phase Not Applicable Completed 1 3 Months Mark Jerome G Mauricio 2020-11-25
Patient satisfaction with psychiatry services during the pandemic Coronavirus disease 19 infection, Psychiatric disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bhabha Atomic Research Centre Hospital India 2020-12-01 CTRI/2020/11/029236 Phase 4 Clinical Recruiting 1 347 Dr Saumitra Nemlekar 2020-11-24
MATCH: MAnaging The COVID-19 in Hemodialysis Coronavirus disease 19 infection, End stage renal disease Dialysis alone Healthy volunteers accepted Hospital Kuala Lumpur Malaysia 2020-12-01 2020-12-31 54601, MATCH, NMRR-20-2484-54601 Phase Not Applicable No longer recruiting 1 1 Month Dr NG YONG MUH 2020-11-25
Clinical Trial to Assess Safety and Immunogenicity of Gam-COVID-Vac Combined Vector Vaccine for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-Сov-2) Infection Coronavirus disease 19 infection Sputnik V alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry Dr Reddy's Laboratories Ltd, Sputnik LLC Gamalei Institute of Epidemiology and Microbiology, Max Neeman International, Russian Direct Investment Fund India 2020-12-31 2021-09-30 CTRI/2020/11/029234, NCT04640233, RDI-GCV-001, RDI-GCV-001 V3.0 Phase 2/Phase 3 Clinical Not yet recruiting 12 9 Months 1600 Akash Khobragade, MD, Asim Das, MD, Dr Anand Kawade, Dr Anil Purty, Dr Jayaprakash Appajigol, Dr Lalit Lakhwani, Dr Manish Kumar Jain, Dr Sandeep Kumar Gupta, Dr Saurabh Agarwal, Dr Shariq Anwar, Dr Shilpa Avarebeel, Dr Sidram Raut, Dr Sonika Newar, Dr Winsley Rose, Dr. Agam Shah, MD, Dr. Lalit Lakhwani, MD, Manish K Jain, MD, N K Arora, MD, S K Raut, MBBS, DIH, Saurabh Agarwal, MD 2020-11-25
A clinical study to assess safety and efficacy of baricitinib in addition to standard care in the treatment of patients hospitalized with COVID-19 pneumonia  Coronavirus disease 19 infection, Viral pneumonia baricitinib alone, standard care alone Jak1 tyrosine kinase inhibitor, Jak2 tyrosine kinase inhibitor BenevolentAI Ltd Biomedical Research Networking Center on Frailty and Healthy Aging (CIBERFES), Diamond Innovative Medicines Initiative, Experimental Cancer Medicine Centre Network, Instituto de Salud Carlos III, National Institute for Health Research (NIHR), National Institutes of Health, National Science Foundation, Swedish Research Council, The European Union UK, Spain, Italy Phase Not Applicable Status not specified 3 166 Professor Justin Stebbing 2020-11-24
Measurement of Quality of food intake, mental health status, and safety measures followed by the hospital support staff during COVID-19 Acute stress disorder, Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Manipal Academy of Higher Education, Welcomgroup Graduate School of Hotel Administration India 2020-11-24 CTRI/2020/11/029221 Phase Not Applicable Not yet recruiting 1 354 Apoorva Jain, Mrs Pallavi Mahesh Shettigar, P Vaishnavi Yadav 2020-11-25
Assessing knowledge, attitudes, perceptions, and practices surrounding COVID-19 and tuberculosis (TB) in Kajang prison staff: a survey study in Kuala Lumpur Coronavirus disease 19 infection Healthy volunteers accepted University of Malaya Malaysia 2021-01-01 2021-08-15 57106, NMRR-20-2483-57106 Phase Not Applicable Status not specified 1 7 Months Dr. NUR AFIQAH BINTI MOHD SALLEH 2020-11-27
COVID-KEDAH: COVID-19 Infection among Healthcare Worker in Kedah Coronavirus disease 19 infection Healthy volunteers accepted Ministry of Health, Malaysia Malaysia 2020-11-17 2021-04-30 57138, COVID-KEDAH, NMRR-20-2478-57138 Phase Not Applicable Status not specified 1 5 Months Dr. ROSIDAH BINTI OMAR 2020-11-27
ACTT-4: Adaptive COVID-19 Treatment Trial 4 Coronavirus disease 19 infection baricitinib plus remdesivir COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, Jak1 tyrosine kinase inhibitor, Jak2 tyrosine kinase inhibitor, RNA polymerase modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Institute of Allergy and Infectious Diseases 2020-11-23 2021-06-30 20-0006 ACTT-4, ACTT-4, NCT04640168 Phase 3 Clinical Not yet recruiting 0 7 Months 1500 20-0006 Central Contact 2020-11-26
Prone Position for Nonintubated Patients With COVID-19 and Hypoxemic Respiratory Failure Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia Prone position alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Pontificia Universidad Catolica De Chile Chile 2020-07-06 2020-09-16 0001, NCT04641182 Phase Not Applicable Completed 1 2 Months 66 2020-11-25
An observational, retrospective study to evaluate the role of thromboprophylaxis regimens on the occurrence of pulmonary embolism in COVID-19 patients Coronavirus disease 19 infection CT pulmonary angiography alone, enoxaparin sodium alone, heparin alone, thromboprophylaxis alone Low molecular weight heparin Universite Libre de Bruxelles Phase Not Applicable Status not specified 0 2020-11-24
Coping during COVID-19: peer-delivered training to improve adolescent wellbeing Coronavirus disease 19 infection, Psychiatric disorder coping based COVID-19 online training alone Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs) University of Oxford Westminster Foundation UK 2020-10-01 2021-03-30 ISRCTN77941736 Phase Not Applicable No longer recruiting 1 5 Months 120 Dr Gabriela Pavarini 2020-11-24
Preventive trial of Homoeopathic medicines in COVID-19 Coronavirus disease 19 infection general hygienic measure teaching alone, healthy dietary advice alone, Variable regimens including Bryonia alba (Hahnemann Publishing Company) , Gelsemium sempervirens (Hahnemann Publishing Company) , ascorbic acid (Dusap Pharmaceuticals) , phosphorus (Hahnemann Publishing Company) Healthy volunteers accepted, Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) D.N. De Homoeopathic Medical College & Hospital, Ministry of Ayush India 2020-11-30 CTRI/2020/11/029265, U1111-1259-4250 Phase 3 Clinical Recruiting 1 20000 Prof Dr Satadal Das, Prof Dr Shyamal Kumar Mukherjee, Prof Dr Subhasish Ganguly 2020-11-25
ACE2-AVG: Angiotensin-converting Enzyme 2 (ACE2) Expression in Tonsils and Adenoids Coronavirus disease 19 infection, Tonsillitis adenoidectomy alone, tonsillectomy alone Assistance Publique Hopitaux de Paris France 2020-12-31 2021-09-30 ACE2-AVG, APHP201032, NCT04640610 Phase Not Applicable Not yet recruiting 9 9 Months 40 André Coste, MD, PhD, Benjamin Verillaud, MD, Bertrand Baujat, MD, PhD, Béatrix Barry, MD, PhD, Diane Evrard, MD, Emilie Bequignon, MD, Fiona Alvin, MD, Frédéric Tankere, MD, PhD, Hélène Morel, Jean-François Papon, MD, PhD, Philippe Herman, MD, PhD, Pierre Bonfils, MD, PhD, Pierre-Louis Tharaux, MD, PhD, Romain Luscan, MD, Sarah Atallah, MD, Vincent Couloigner, MD, PhD 2020-11-25
A phase II study of REVTx-99 for the treatment of early stage COVID‑19 patients at risk for hospitalization Coronavirus disease 19 infection REVTx-99 alone TLR-4 agonist Revelation Biosciences Phase 2 Clinical Planned 0 2020-11-24
An observation and comparison of the efficacy and relative satisfaction of health care workers while being monitored by the standard buddy technique versus the remote audio visual doffing surveillance (RADS) of the doffing process during the COVID-19 pandemic Coronavirus disease 19 infection remote audio visual surveillance technique alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Nehru HOSPITAL, Postgraduate Institute of Medical Education and Research India 2020-12-15 CTRI/2020/11/029233 Phase Not Applicable Not yet recruiting 1 200 Naveen Naik B 2020-11-24
An observational study for hospitalized patients with CAP, HAP and VAP Coronavirus disease 19 infection, Pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Nagoya University Hospital Japan 2020-11-24 UMIN000042522 Phase Not Applicable Recruiting 2 1500 Yuichiro Shindo 2020-11-25
Role Of Montelukast In Management Of COVID 19 Coronavirus disease 19 infection montelukast sodium alone, standard treatment alone Leukotriene D4 antagonist Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences Patna India 2020-11-25 CTRI/2020/11/029232 Phase 3 Clinical Not yet recruiting 1 90 DR VIJAY KUMAR 2020-11-25
The effect of the online child birth preparation classes on pregnant women during COVID-19 pandemic Anxiety disorder, Coronavirus disease 19 infection online child birth preparation educational session alone Female Tehran University of Medical Sciences Iran 2020-11-21 IR.TUMS.FNM.REC.1399.098, IRCT20190713044192N2 Phase Not Applicable Recruiting 1 100 Farnaz Farnam, Mohammadali Sahraeian 2020-11-26
A clinical trial of Siddha drugs M V kashayam (internally) for the management and treatment of COVID-19 Coronavirus disease 19 infection MV kashayam intake alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Arul Anandar College Madurai Herbal Market India 2020-11-25 CTRI/2020/11/029289 Phase 2/Phase 3 Clinical Not yet recruiting 1 130 Dr P Dharumarajan 2020-11-25
Impact of COVID-19 on screen time, physical activity, sleep pattern and food intake among students of 18 to 23 years Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs) Manipal Academy of Higher Education, Welcomgroup Graduate School of Hotel Administration India 2020-11-23 CTRI/2020/11/029235 Phase Not Applicable Not yet recruiting 1 478 Pallavi Mahesh Shettigar, Reshma Mariam Santhosh 2020-11-24
Group CBT for Intolerance of Uncertainty Coronavirus disease 19 infection, Generalized anxiety disorder Cognitive-behavioral treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Manitoba Canada 2020-11-30 2021-08-31 H2019:412, NCT04512378 Phase Not Applicable Not yet recruiting 1 9 Months 20 Elizabeth Hebert, PhD 2020-11-25
Psychotherapy Strategies for the Treatment of Professionals and Students From Essential Services With High Levels of Emotional Distress in the Context of COVID-19 Anxiety disorder, Coronavirus disease 19 infection, Depression Brief Interpersonal Telepsychotherapy alone, Cognitive Behavioral Brief-Telepsychotherapy alone Hospital de Clinicas de Porto Alegre Brazil 2020-11-05 2021-07-20 20200213_TREATMENT, NCT04635618 Phase Not Applicable Recruiting 1 8 Months 999 Giovanni Salum, MD, PhD 2020-11-25
ProneSpontCov: Awake Prone Position to Reduce Ventilation Inhomogeneity in COVID-19 Acute Respiratory Failure Coronavirus disease 19 infection, Respiratory failure Electrical impedance tomography (EIT) alone, lung ventilation in awake prone position alone, lung ventilation in dorsal decubitus alone, lung ventilation in ventral decubitus alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux De Marseille France 2020-04-04 2021-01-31 2020-17, NCT04632602, ProneSpontCov Phase Not Applicable Recruiting 1 9 Months 20 Christophe GUERVILLY, Jean-Olivier ARNAUD 2020-11-25
Evaluation of the Effects of L-carnitine Supplementation on Patients with COVID-19 Coronavirus disease 19 infection Variable regimens including L-carnitine (Karen Company) , dexamethasone , favipiravir , interferon-beta RNA polymerase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Hamadan University of Medical Sciences Iran 2020-11-20 IR.UMSHA.REC.1399.650, IRCT20200921048794N1 Phase 3 Clinical Recruiting 1 96 Dr Saman Talebi, Mehran Ghasemi, Rasool Haddadi, Saeed Bashirian 2020-11-25
A randomized, double-blind, placebo-controlled, phase III clinical trial of the effectiveness and safety of inoculation of recombinant new coronavirus vaccine (CHO cells) in the prevention of COVID-19 in people 18 years and older Coronavirus disease 19 infection SARS-CoV-2 protein subunit vaccine (COVID-19), Chongqing Zhifei Biological Products/ Institute of Microbiology, Chinese Academy of Sciences alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hunan Province Centers for Disease Control and Prevention China 2020-11-06 2021-12-31 ChiCTR2000040153 Phase 3 Clinical Not yet recruiting 1 13 Months 29000 Li Fangjun, Zhong Zaixin 2020-11-25
A Phase II clinical trial of novel coronavirus pneumonia (COVID-19) mRNA Vaccine (BNT-162b2) in China Coronavirus disease 19 infection, Viral pneumonia BNT-162b2 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry Jiangsu Province Centers for Disease Control and Prevention Shanghai Fosun Pharmaceutical Industry Development Co Ltd China 2020-11-23 2021-12-31 ChiCTR2000040044 Phase 2 Clinical Not yet recruiting 2 13 Months 960 Wang Wei, Zhu Fengcai 2020-11-27
A phase II, randomized, double-blind, placebo-controlled study to evaluate the safety and efficacy of leronlimab as a treatment for COVID-19 patients suffering from long-hauler symptoms Coronavirus disease 19 infection leronlimab alone CCR5 chemokine antagonist CytoDyn Inc US Phase 2 Clinical Planned 1 102 Dr Chris Recknor, Dr Kush Dhody, Dr Mahboob Rahman 2020-11-27
Pharmacokinetics, Safety, and Tolerability of CSL-760, an Anti-COVID-19 Hyperimmune Intravenous Immunoglobulin, in Healthy Adult Subjects Coronavirus disease 19 infection CSL-760 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) CSL Behring LLC 2020-12-31 2021-04-30 CSL760_1001, NCT04638634 Phase 1 Clinical Not yet recruiting 0 4 Months 24 Study Director, Trial Registration Coordinator 2020-11-25
Short- and Long-term Effects of Adding Oral L-arginine to Standard Therapy in Patients With COVID-19 (SARS-CoV-2) Coronavirus disease 19 infection, Viral pneumonia Bioarginina (L-arginine) alone, standard therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Campania Luigi Vanvitelli Italy 2020-11-18 2021-09-18 BIOARGININA, NCT04637906 Phase Not Applicable Not yet recruiting 1 10 Months 290 Giuseppe fiorentino 2020-11-25
A virtual global clinical trial to assess ePRO measures using Migraine Buddy mobile tracking app for an acute migraine medication in COVID-19 pandemic Coronavirus disease 19 infection, Migraine Migraine Buddy mobile tracking app alone Healint Pte Ltd 2020-11-18 COVID19_IMPACT Phase Not Applicable Recruiting 0 2020-11-23
Questionnaire Regarding the Effect of Wearing Face Masks on Oral Health Coronavirus disease 19 infection, Halitosis, Xerostomia face mask alone Healthy volunteers accepted University of Gottingen University Medical Center Goettingen Germany 2020-11-20 2021-07-01 FACEMASKS-ORALHEALTH, NCT04632004 Phase Not Applicable Recruiting 1 7 Months 3000 Philipp Kanzow, Dr. med. dent., Dr. rer. medic 2020-11-26
Effect of Home Exercise Activity on Cortisol and Depression in COPD During the Pandemic COVID Chronic obstructive pulmonary disease, Coronavirus disease 19 infection, Depression bicycle alone, moderate intensity home-exercise training alone, treadmill alone, upper and lower limb exercise alone Male, Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Cairo University Egypt 2020-11-19 2021-03-01 NCT04639349, P.T.REC/012/002897 Phase Not Applicable Recruiting 1 3 Months 40 Ali Ismail, lecturer, Ali Mohamed Ali ismail 2020-11-26
Testing Scalable, Single-Session Interventions for Adolescent Depression in the Context of COVID-19 Coronavirus disease 19 infection, Depression behavioral activation SSI alone, growth mindset SSI alone Adolescents (13-17 yrs) State University of New York at Stony Brook University of Denver US 2020-11-19 2021-07-31 1505797-3, NCT04634903 Phase Not Applicable Recruiting 1 8 Months 2400 Jessica L Schleider, PhD 2020-11-25
COVID PLEX+CCP: Plasma Exchange (PLEX) and Convalescent Plasma (CCP) in COVID-19 Patients With Multiorgan Failure Coronavirus disease 19 infection, Hypoxia, Multiple organ failure centrifuge plasma exchange therapy alone, membrane plasma exchange therapy alone, standard care alone, Variable regimens including albumin , citrate , convalescent plasma , fresh frozen plasma , heparin Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rigshospitalet Aalborg Hospital, Aarhus University Hospital, Odense University Hospital, Zealand University Hospital Denmark 2020-11-16 2022-06-30 COVID PLEX+CCP, H-20041716, NCT04634422 Phase 2 Clinical Not yet recruiting 1 19 Months 220 Anders Perner, Prof, Nicholas Carlson, MD, Wladimir M Szpirt, MD, Wladimir Szpirt 2020-11-25
A Synthetic MVA-based SARS-CoV-2 Vaccine, COH04S1, for the Prevention of COVID-19 Coronavirus disease 19 infection COH-04S1 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) City of Hope Medical Center National Cancer Institute US 2020-11-25 2022-11-10 20447, NCI-2020-08335, NCT04639466, P30CA033572 Phase 1 Clinical Recruiting 1 23 Months 129 John Zaia 2020-11-26
Targeting the Health Care Provider (HCP) Burnout Crisis During the COVID-19 Pandemic Acute stress disorder, Coronavirus disease 19 infection Transcendental meditation alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Duke University US 2020-11-30 2021-04-30 NCT04632368, PRO00106191 Phase Not Applicable Not yet recruiting 1 5 Months 80 Catherine Clinical Research Co-ordinator, Taylor Clinical Research Co-ordinator 2020-11-26
BRIDGE: Building Regulation in Dual Generations - Telehealth Model Coronavirus disease 19 infection, Depression BRIDGE therapy program alone, dialectical behavior therapy alone Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Manitoba Centre for Addiction and Mental Health, Research Manitoba, University of Oregon Canada 2020-09-01 2021-05-31 BRIDGE, BRIDGEV2.0, NCT04639557 Phase Not Applicable Recruiting 1 9 Months 40 2020-11-23
EUDOCO: Early Versus Delayed Intubation of Patients With COVID-19 Coronavirus disease 19 infection, Hypoxia, Respiratory failure endotracheal intubation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Evangelismos Hospital Greece 2020-11-18 2021-05-01 32635, 13-10-2020, EUDOCO, NCT04632043 Phase Not Applicable Not yet recruiting 1 5 Months 80 Ilias Siempos, MD, DSc 2020-11-26
Patient Centered Intervention to Prevent Tuberculosis Among Children < 5 Years Old Coronavirus disease 19 infection, Mycobacterium tuberculosis infection educational booklet alone, isoniazid alone, isoniazid preventive therapy alone, weekly SMS alone, weekly children storybook session alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidad Peruana Cayetano Heredia Peru 2019-12-01 2023-12-15 103161, NCT03881228 Phase 2 Clinical Recruiting 1 48 Months 300 Larissa Otero, MD PhD, Larissa Otero, PhD 2020-11-26
Telepsychoeducation for the Prevention of Emotional Distress in Professionals and Students From Essential Services in the Context of COVID-19 Acute stress disorder, Coronavirus disease 19 infection telepsychoeducation with personalized videos alone Hospital de Clinicas de Porto Alegre Brazil 2020-11-05 2021-07-20 20200213_PREVENTION, NCT04632082 Phase Not Applicable Recruiting 1 8 Months 2200 Giovanni Salum, MD, PhD 2020-11-23
The Effect of Ganglion Sphenopalatine Block (SPG-block) Versus Placebo on Persistent Headache Following Acute COVID-19 Infection Coronavirus disease 19 infection, Headache ganglion sphenopalatine block (SPG block) alone, lidocaine plus ropivacaine Sodium channel inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Bispebjerg and Frederiksberg Denmark 2020-12-31 2021-11-30 GSPB-COVID-2020, NCT04636034 Phase 3 Clinical Not yet recruiting 1 11 Months 60 Christian S Meyhoff, PhD, Mads S Jespersen, MD, Mads Seit Jespersen 2020-11-24
COVID_CRC: The Impact of Covid-19 Pandemic on Colorectal Cancer Prevention Due to Delays in Diagnosis: a Global Study Colorectal tumor, Coronavirus disease 19 infection Colonoscopy alone Istituto Clinico Humanitas Italy 2020-12-16 2021-03-31 100, COVID_CRC, NCT04637893 Phase Not Applicable Not yet recruiting 1 3 Months 1000 Alessandro Repici, MD, Roberta Maselli, MD 2020-11-24
Online Trial of Meditation and Behavior Coronavirus disease 19 infection Loving-Kindness Meditation training alone, Relaxation Meditation training alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Georgetown University US 2020-11-20 2021-11-20 2010-180-2, NCT04632875 Phase Not Applicable Recruiting 1 12 Months 68 Abigail A Marsh, PhD, Study Coordinator 2020-11-23
NeuroCovid Rehab and Recovery Related to COVID-19 Diagnosis Coronavirus disease 19 infection, Neurological disease Soterix taVNS model 0125-LTE stimulator alone, transcutaneous auricular vagus nerve stimulation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Medical University of South Carolina National Institute of General Medical Sciences, National Institutes of Health US 2020-11-30 2021-06-30 00101270, NCT04638673, U54GM104941-08 Phase 2 Clinical Not yet recruiting 1 7 Months 30 Mark S George, MD, Morgan Dancy, BA, Sarah Huffman, BA 2020-11-24
Prayer in Commbate to Corona Virus - COVID-19 Coronavirus disease 19 infection prayers by theologians alone, protcol treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital do Coracao Brazil 2020-08-01 2021-01-31 NCT04631380, PRAYER-COVID19 Phase Not Applicable Recruiting 1 6 Months 200 Alexandre B Cavalcanti, MD, PhD, NATHAN V SOUBIHE JR, sabrina bernardez 2020-11-24
Video Home Visits for Dietary Counselling Coronavirus disease 19 infection, Urolithiasis urologist and dietitian virtual home visits alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of California San Francisco US 2021-01-01 2024-07-01 NCT04634851, UCSFUROVV Phase Not Applicable Not yet recruiting 1 42 Months 100 David Bayne, MD, MPH, Marshall Stoller, MD 2020-11-24
UNITED: At-Home Infusion Using Bamlanivimab in Participants With Mild to Moderate COVID-19 Coronavirus disease 19 infection bamlanivimab alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Aged Adults (65-79 yrs), Elderly Adults (80 and over) UnitedHealth Group Inc Eli Lilly & Co, Optum Inc 2020-11-30 2021-05-31 2020-0081, NCT04639479, UNITED Phase 4 Clinical Not yet recruiting 0 6 Months 7500 Dan Griffin, MD PHD, Michelle Tanner, BA, Tracy Ziolek, MS 2020-11-24
Co-VIS: Benefits of Using a Transparent Visor to Replace the Face Mask in Speech Therapy Rehabilitation of Oral-Linguo-Facial Praxies in the Context of COVID-19: a Series of Cases Apraxia, Coronavirus disease 19 infection speech therapy rehabilitation alone, transparent covering visor alone, video sequence watching alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-11-30 2021-02-28 APHP200876, Co-VIS, IDRCB, NCT04639427 Phase Not Applicable Not yet recruiting 1 3 Months 4 Julie PAQUEREAU, MD 2020-11-25
NOSO-COR IMMUNO: COVID-19 - Multicenter Study on Nosocomial Transmission of SARS-CoV-2 Virus: an Ancillary Study Coronavirus disease 19 infection blood sampling alone, nasopharyngeal sampling alone, salivary sampling alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospices Civils De Lyon France 2020-11-23 2021-11-01 69HCL20_0761, NCT04637867, NOSO-COR IMMUNO Phase Not Applicable Not yet recruiting 1 11 Months 200 MITRA ELAHI, PhD, Philippe VANHEMS, MD 2020-11-25
REHABCOVID: Organization of Pulmonary Rehabilitation of Post-COVID-19 Patient With Sequela Anxiety disorder, Coronavirus disease 19 infection, Depression, Dyspnea, Fatigue, Respiratory disease aerobic exercise alone, ergocycle alone, heart rate monitor alone, medical consultation alone, muscle strengthening exercise alone, occupational therapy alone, psychomotricity alone, respiratory tele-rehabilitation program alone, sophrology alone, walking exercise alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer France 2020-11-30 2022-01-31 2020-A02838-31, 2020-CHITS-06, NCT04634318, REHABCOVID Phase Not Applicable Not yet recruiting 2 14 Months 118 Asmaa Jobic, Charles Simon, MD, Jean-Marc Vallier, MD, Nicolas Paleiron, MD 2020-11-28
Online Multi-component Psychological Intervention for Prevention of Grief Disorder Due to COVID-19 Anxiety disorder, Coronavirus disease 19 infection, Depression, Post traumatic stress disorder, Sleep disorder Multi-component psychological online intervention alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Universidad Internacional de Valencia Universidad Autonoma de Ciudad Juarez, Universidad Nacional Autonoma De Mexico, University of Buenos Aires Mexico 2020-12-15 2021-06-01 NCT04638842, VIU-GRIEF-COVID Phase Not Applicable Not yet recruiting 1 5 Months 42 Alejandro Dominguez Rodriguez, PhD, Anabel de la Rosa, Gómez, Carlos Armando Arzola, MD, Esteban Eugenio Esquivel Santoveña, PhD, Flor Rocío Ramírez Martínez, PhD, Luis Farfallini, PhD, María Jesús Hernández Jimenez, PhD, Paulina Arenas Landgrave, PhD, Rosa Olimpia Castellanos Vargas, MD, Sofía Cristina Martínez Luna, MD 2020-11-25
An observational, retrospective, propensity-matched study to evaluate the impact of famotidine use on clinical outcomes of hospitalized patients with COVID-19 Coronavirus disease 19 infection famotidine alone Histamine H2 receptor antagonist Hartford Hospital US Phase Not Applicable Status not specified 1 878 2020-11-23
CureCovid-2019: A Study to Compare the Efficacy of GNS-561 Versus Standard of Care in Patients With SARS-CoV-2 (COVID-19) Infection Coronavirus disease 19 infection GNS-561 alone, standard of care alone Autophagy protein inhibitor, Solute carrier family inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Genoscience France 2020-11-18 2021-10-30 CureCovid-2019, GNS561-CL-I-Q-0291, NCT04637828 Phase 2 Clinical Recruiting 1 11 Months 178 Christelle Ansaldi, Christelle Ansaldi, MD 2020-11-25
Polio Vaccine (IPV) for SARS-CoV-2 and Prevention of Coronavirus Disease (COVID-19) Coronavirus disease 19 infection polio vaccine, Sanofi Pasteur alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) US 2020-11-15 2021-01-15 EMO-001, NCT04639375 Phase 4 Clinical Recruiting 2 2 Months 25 Brittany Comunale, John Andrews, John Andrews, PhD 2020-11-28
COVIFAT: Impact of Adipose Tissue in COVID-19 Coronavirus disease 19 infection, Inflammatory disease, Obesity adipose tissue sampling alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-11-23 2021-11-23 2020-A02403-36, APHP200983, COVIFAT, NCT04639440 Phase Not Applicable Not yet recruiting 1 12 Months 60 Fabienne FOUFELLE, Dr, Olivier BOURRON, Dr 2020-11-24
A phase III trial of AMY-101 for the treatment of severe COVID-19 patients Coronavirus disease 19 infection AMY-101 alone Complement C3 inhibitor University of Pennsylvania Brazil Phase 3 Clinical Planned 1 2020-11-23
The effect of massage training on the resilience of pregnant women Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression telemedicine-based massage training alone Female, Young Adults (18-44 yrs) Islamic Azad University Iran 2020-11-04 IR.IAU.MSHD.REC.1399.159, IRCT20170607034378N2 Phase Not Applicable Recruiting 2 120 Ali Asghar Mahmudi, Dr Saeed Khayat Moghadam, Fatemeh Jalal Marvi, Mahdi Sayad Kame Olya 2020-11-24
The role of hemoperfusion in COVID-19 Coronavirus disease 19 infection, Respiratory failure Standard of care treatment alone, hemoperfusion alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shaheed Beheshti Medical University Iran 2020-10-17 IR.SBMU.RETECH.REC.1399.582, IRCT20200608047686N2 Phase 2 Clinical Recruiting 1 40 Afshin Zarghi, Muhanna Kazempour 2020-11-24
COVID-19 pandemic effects on depression, anxiety and help-seeking attitudes in college students Anxiety disorder, Coronavirus disease 19 infection, Depression SurveyMonkey platform alone Healthy volunteers accepted University of Porto Portugal 2019-02-01 2021-06-01 ISRCTN63459073, PMHDS-1 Phase Not Applicable No longer recruiting 1 28 Months 500 Mrs Virginia Conceicao 2020-11-25
Qualitative Study: Issues Faced by Female Staffs During the Pandemic COVID-19 Coronavirus disease 19 infection Hospital Tuanku Fauziah Malaysia 2020-11-23 2021-04-30 57017, NMRR-20-2507-57017 Phase Not Applicable Not yet recruiting 1 5 Months Dr Noor Melissa Binti Nor Hadi 2020-11-23
TECOVID: Thrombotic Complications Among COVID-19 Patients: A Multicenter Study from a Malaysian Perspective Coronavirus disease 19 infection, Phlebothrombosis Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universiti Teknologi Mara Malaysia 2020-12-01 2021-11-30 56439, NMRR-20-2465-56439, TECOVID Phase Not Applicable Status not specified 2 12 Months 3035 Dr Hanis Hanum Zulkifly, Dr Lee Chew Kiok, Dr Leong Chee Loon 2020-11-24
Cross-Sectional Study: Factors Contributing to Burnout Among Healthcare Workers in Sabah Coronavirus disease 19 infection, Psychiatric disorder Healthy volunteers accepted Hospital Tuanku Fauziah Malaysia 2020-12-01 2021-04-30 57139, NMRR-20-2494-57139 Phase Not Applicable Not yet recruiting 3 5 Months Dr Noor Melissa Binti Nor Hadi 2020-11-26
Management of Depression and Anxiety in HF Anxiety disorder, Cardiac failure, Coronavirus disease 19 infection, Depression web-based COMPASS intervention alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) King's College London UK 2020-10-02 2021-08-16 IRAS ID: 268951, NCT04636944 Phase Not Applicable Recruiting 1 10 Months 13 Annmarie Grealish, Catherine Evans, Sameera Helal, Silapiya Smith 2020-11-24
An observational, retrospective, cohort study to investigate the potential hepatotoxicity of lopinavir/ritonavir in severely ill patients for the treatment of COVID-19 infection Coronavirus disease 19 infection, Hepatotoxicity drug-induced lopinavir + ritonavir alone HIV protease inhibitor Centre Hospitalier Regional Universitaire de Lille Phase Not Applicable Status not specified 0 42 2020-11-24
Short Term Effects in Pulmonary Function Among COVID-19 Recovered Adult Patients in a Tertiary Hospital in Davao City Coronavirus disease 19 infection, Dyspnea Southern Philippines Medical Center Philippines 2021-01-18 2021-04-18 PHRR201110-003113 Phase Not Applicable Not yet recruiting 1 3 Months Benjo P. Ato, Christoper John Q. Quadra 2020-11-23
COVID-CMR: Prevalence of Myocardial Scars on CMR After COVID-19 Infection Coronavirus disease 19 infection, Myocardial disease Cardiac Magnetic Resonance Imaging alone, ECG monitoring alone, treadmill exercise test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Bordeaux Universite de Bordeaux France 2020-06-13 2021-04-13 CHUBX 2020/22, COVID-CMR, NCT04636320 Phase Not Applicable Recruiting 1 10 Months 240 Hubert COCHET, MD-PhD, Nathalie COTTIGNIES, Pierre JAïS, MD-PhD 2020-11-23
Phase I Trial of a Recombinant SARS-CoV-2 Vaccine (CHO Cell) Coronavirus disease 19 infection SARS-CoV-2 vaccine (CHO Cell) alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry Jiangsu Province Centers for Disease Control and Prevention Chinese Academy of Medical Military Sciences, Liaoning Maokangyuan, Zhongyi Anke Biotechology Co Ltd China 2020-10-30 2022-01-07 JSVCT096, NCT04636333 Phase 1 Clinical Recruiting 1 14 Months 216 Fanyue Meng, Doctor, Fengcai Zhu, Doctor, Mingwei Wei 2020-11-24
Effect of Vitamin D on Hospitalized Adults With COVID-19 Infection Coronavirus disease 19 infection cholecalciferol alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Liege Laboratoires SMB SA Belgium 2020-11-12 2021-02-28 D-COVID, NCT04636086 Phase 4 Clinical Recruiting 1 3 Months 100 Anne-Françoise Rousseau, Anne-Françoise Rousseau, MD, PhD 2020-11-23
PEACE: Perceptions, Experiences, and Activity in Cancer Survivors During COVID-19 Cancer, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Nebraska US 2020-12-01 2021-06-30 768-20, NCT04637295, PEACE Phase Not Applicable Not yet recruiting 1 7 Months 1000 Diane K Ehlers, PhD, Lindsey Page, MS, Nicholas J Foggia, MS 2020-11-23
A clinical trial of light activated photodynamic compound vaccine (COVID-19 infection), Theralase Technologies/University of Manitoba for the potential treatment of COVID-19 infection Coronavirus disease 19 infection light activated photodynamic compound vaccine (COVID-19 infection), Theralase Technologies/University of Manitoba alone Theralase Technologies Inc Phase Not Applicable Planned 0 2020-11-23
Methylene Blue Treatment of COVID-19 Coronavirus disease 19 infection methylene blue alone, standard therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Epatocentro Ticino Foundation Switzerland 2020-11-30 2022-12-31 MB TREATMENT OF COVID19, NCT04635605 Phase 2 Clinical Not yet recruiting 1 25 Months 64 Andreas Cerny, Prof, Maurizia Bissig 2020-11-24
MEDEAS: Methylprednisolone Versus Dexamethasone in COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia methylprednisolone alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) L'Universita Degli Studi di Trieste Centro Di Riferimento Oncologico (CRO Aviano), Istituto Nazionale Per Le Malattie Infettive "Lazzaro Spallanzani" Italy 2020-11-25 2021-04-30 MEDEAS, MEDEAS1, NCT04636671 Phase 3 Clinical Not yet recruiting 1 5 Months 680 Francesco Salton, MD, Marco Confalonieri, MD 2020-11-24
KORANIT: Serological Diagnostics of COVID-19 in Health Care Workers Coronavirus disease 19 infection blood test alone, nasal swab test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University Medical Centre Ljubljana Slovenia 2020-11-30 2021-01-31 KOAIT-1-2020, KORANIT, NCT04635592 Phase Not Applicable Not yet recruiting 1 2 Months 300 Marko Zlicar, MD, PhD, Peter Poredos, Assist. prof, Peter Poredos, MD, PhD 2020-11-27
An observational comparative study on the effects of second week methylprednisolone pulses in patients with severe coronavirus disease 2019 pneumonia Coronavirus disease 19 infection, Pneumonia methylprednisolone alone Hospital de Cruces Spain Phase Not Applicable Status not specified 1 242 2020-11-23
Study of a Recombinant Coronavirus-Like Particle COVID-19 Vaccine in Adults Coronavirus disease 19 infection MT-2766 alone TLR-9 agonist Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Medicago Inc GlaxoSmithKline plc Europe, Canada, US, North America 2020-11-19 2022-04-30 CP-PRO-COVLP-021, NCT04636697 Phase 2/Phase 3 Clinical Not yet recruiting 2 17 Months 30612 Brian Ward, MD, Mary Hardison 2020-11-23
Personalized Phage Treatment in COVID-19 Patients With Bacterial Co-Infections Microbials for Pneumonia or Bacteremia/Septicemia Acinetobacter baumannii infection, Bacterial infection, Coronavirus disease 19 infection, Pseudomonas aeruginosa infection, Sepsis, Staphylococcus aureus infection, Viral pneumonia Phage Therapy alone, anti-microbial therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Adaptive Phage Therapeutics Inc APT.APS.001, NCT04636554 Phase Not Applicable Recruiting 0 Robert J Hopkins, MD, MPH&TM, FACP, FIDSA, Stephanie Holland 2020-11-24
Burden of COVID-19 Infection in Populations With High or Low Risk of Infection Coronavirus disease 19 infection, Post traumatic stress disorder app alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Neuromed IRCCS Italy 2020-12-15 2022-06-15 DEP_032020, NCT04636203 Phase Not Applicable Not yet recruiting 1 18 Months 3500 Chiara Cerletti, MS, Licia Iacoviello, MD, PhD 2020-11-24
A large clinical diagnostic study to assess COVID-19 in exhaled breath condensate (EBC) using CoronaCheck diagnostic test Coronavirus disease 19 infection CoronaCheck diagnostic test alone Exhalation Technology Limited UK 2020-11-02 Phase Not Applicable Recruiting 1 300 Anoop Chauhan 2020-11-25
Immune Profiling with Antibody-based COVID-19 Testing Coronavirus disease 19 infection, Multiple myeloma Antibody-based COVID-19 Testing alone African Ancestry Quest Diagnostics Inc Dana-Farber Cancer Institute Inc US Phase Not Applicable Status not specified 1 1000 Irene Ghobrial, MD 2020-11-20
Vital Sensor Monitors for CV19 Detection Coronavirus disease 19 infection ANNE One wireless vital sign monitoring device alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Northwestern University US Department of Defense US 2020-11-05 2022-10-30 NCT04635787, STU00213040 Phase Not Applicable Recruiting 1 23 Months 300 Shuai (Steve) Xu 2020-11-23
RECIPE: Restoring Non-Emergent Cardiovascular Care in the Peri- COVID-19 Era Coronavirus disease 19 infection cardiac procedures alone Healthy volunteers accepted Pinnacle Health US 2020-08-01 2022-06-30 NCT04636021, RECIPE, UPMCP- 20-007 Phase Not Applicable Recruiting 1 23 Months 1000 William Bachinsky MD, William Bachinsky, MD 2020-11-23
INHALE-HEP: Inhaled Heparin for Hospitalized COVID-19 Patients Coronavirus disease 19 infection standard care alone, unfractionated heparin alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The Australian National University Helwan University Egypt, Argentina 2020-06-01 2021-06-01 INHALE-HEP, INHALE-HEP META-TRIAL, NCT04635241 Phase 2/Phase 3 Clinical Recruiting 2 12 Months 656 Alicia B Vilaseca, PhD, Frank MP van Haren, MD, PhD, Frank van Haren, Tarek I Ismail 2020-11-24
H2Covid: Hydrogen Therapy in Patients With Moderate Covid-19 Coronavirus disease 19 infection conventional oxygen therapy alone, hydrogen therapy alone, nasal cannula alone, Variable regimens including hydrogen , nitrogen , oxygen Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Grenoble France 2020-12-01 2021-09-30 38RC20.277, H2Covid, NCT04633980 Phase 1 Clinical Not yet recruiting 1 10 Months 10 BOUCHER François, PhD, Jean Paul Brion, MD, Saber TOUATI, PhD 2020-11-23
Impact of Social Distancing on Bariatric Versus Non-Surgical Obese Patients During COVID-19 Pandemic Coronavirus disease 19 infection, Obesity bariatric surgery alone, medical weight management alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Singapore General Hospital Pte Ltd Singapore 2020-06-01 2020-07-30 HENRYLEW, NCT04633941 Phase Not Applicable Completed 1 1 Month 272 Chin Hong Lim, FRCS 2020-11-27
Borderline COVID-19 PCR Test Result Coronavirus disease 19 infection PCR test alone Jessa Hospital Belgium 2020-08-01 2020-12-30 F/2020/166, NCT04636294 Phase Not Applicable No longer recruiting 1 4 Months 30000 2020-11-23
The Impact of COVID-19 Pandemic on Thyroid Surgery in Italy: Results From a Nation-wide, Multicentric Study Coronavirus disease 19 infection, Thyroid disease Thyroidectomy alone University of Cagliari Italy 2020-03-10 2020-11-12 NCT04635813, THYCOVIT Phase Not Applicable Completed 1 8 Months 3800 Fabio Medas 2020-11-23
PallPan AP 4: COVID-19: National strategy for palliative care during times of a pandemic - generalst palliative care in hospitals Coronavirus disease 19 infection focus group interview alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitätklinikum Düsseldorf Bundesministerium für Bildung und Forschung Germany 2020-12-01 2020-1119, DRKS00023595, PallPan AP 4 Phase Not Applicable Not yet recruiting 1 30 Martin Neukirchen 2020-11-23
A phase I clinical trial of TNX-1800 for the potential prevention of COVID-19 infection Coronavirus disease 19 infection TNX-1800 alone COVID19 Spike glycoprotein modulator Tonix Pharmaceuticals Holding Corp Phase 1 Clinical Planned 0 2020-11-20
A phase III trial of PegiHep for the treatment of COVID-19 Coronavirus disease 19 infection peginterferon alfa-2b follow-on-biologic, Zydus-Cadila alone Interferon alpha 2 ligand Zydus-Cadila Group India Phase 3 Clinical Planned 1 2020-11-23
Effect of Ivermectin in treatment of COVID-19 Coronavirus disease 19 infection Variable regimens including Lopinavir/Ritonavir , hydroxychloroquine sulfate , interferon beta-1a follow-on biologic (intramuscular), CinnaGen , ivermectin Chloride channel modulator, Interferon beta ligand Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bandare-abbas University of Medical Sciences Iran 2020-11-15 IR.HUMS.REC.1399.410, IRCT20200506047323N6 Phase 3 Clinical Recruiting 1 120 Mahdi Hasani Azad, Mohammad Fathalipour 2020-11-26
Phase I Clinical Trial on NK Cells for COVID-19 Coronavirus disease 19 infection natural killer cells alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital de Clinicas de Porto Alegre Brazil 2021-01-02 2021-03-30 20200210, NCT04634370 Phase 1 Clinical Not yet recruiting 1 2 Months 24 Annelise Pezzi, PhD, Lucia Silla, MD, PhD, Lucia Silla, Md, PhD 2020-11-23
COV-HD: Antibody Response in Hemodialysis and Non-dialysis Patients Diagnosed With COVID-19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Saint Petersburg State University Russian Federation 2020-11-30 2021-08-31 COV-HD, COVID, NCT04633915 Phase Not Applicable Not yet recruiting 1 9 Months 40 Ekaterina Parshina 2020-11-23
An observational study on the factors associated with prolonged viral shedding and impact of lopinavir/ritonavir treatment in hospitalized non-critically ill patients with SARS-CoV-2 infection Coronavirus disease 19 infection lopinavir + ritonavir alone HIV protease inhibitor Zhengzhou University China Phase Not Applicable Status not specified 1 120 2020-11-19
Ezrin Peptide (HEP-1) for Treatment of Coronavirus Disease (COVID-19) Infection Coronavirus disease 19 infection Gepon alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Shaheed Beheshti Medical University praxisgemeinschaft für zelltherapie Iran 2020-12-20 2021-04-01 IR.SBMU.REC.1399.023, NCT04627233 Phase 1 Clinical Not yet recruiting 1 3 Months 20 Farzad Ashrafi 2020-11-23
A Study Evaluating the Efficacy and Safety of CKD-314 in Hospitalized Adult Patients Diagnosed With COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia nafamostat (COVID-19 infection), Institut Pasteur Korea alone, standard of care alone Serine protease inhibitor, Transmembrane serine protease 2 inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Chong Kun Dang Pharmaceutical Corp South Korea 2020-11-20 2021-06-30 A108_01CVD2013, NCT04628143 Phase 2 Clinical Not yet recruiting 1 7 Months 100 Dongho Kim, MD 2020-11-24
The Severity of COVID-19 in Diabetes and Non-diabetes Patients (COVID-19) Coronavirus disease 19 infection, Diabetes mellitus Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dr. A. Ramachandran's Diabetes Hospitals, India Diabetes Research Foundation India 2020-11-16 2021-05-16 IDRFARH015, NCT04634214 Phase Not Applicable Not yet recruiting 4 6 Months 1050 Ambady Ramachandran, M.D,PhD,DSc, Palaniappan T, M.D, Sruti Chandrasekaran, M.D.,D.M, Su Thillai Vallal, M.D, Subair Khan, M.S 2020-11-23
STOP Severe COVID-19: Study To antagonize Plasminogen Activator Inhibitor-1 in Severe COVID-19 Coronavirus disease 19 infection TM-5614 alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Northwestern University US 2020-11-16 2022-06-30 NCT04634799, STOP Severe COVID-19, STU00213262 Phase 1/Phase 2 Clinical Recruiting 1 19 Months 80 Anna Huskin, RN, Douglas E Vaughan, MD, Lyndsay Christensen, MSN, Sanjiv J Shah, MD, Sanjiv Shah, MD 2020-11-23
MP-COVID: The MentalPlus for Assessment and Rehabilitation of Cognitive Function After Remission of the Symptoms of COVID-19 Cognitive disorder, Coronavirus disease 19 infection MentalPlus digital game alone Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Sao Paulo Brazil 2020-11-08 2023-12-29 MENTALPLUS, MP-COVID, NCT04632719 Phase Not Applicable Recruiting 1 37 Months 200 Julia S Valentin, Fellow, Julia S. Valentin, Fellow, Julia SS Valentin, Bacharel, Livia S. Valentin, Ph.D, Livia S. Valentin, Ph.D., Livia SS Valentin, Ph.D, Livia Stocco S Valentin, Ph.D, Luiz Antonio M Cesar, Ph.D, Luiz Aparecido Bortolotto, Ph.D 2020-11-25
EpiSARS2: Prevalence and Risk Factors of COVID-19 in the Upper Silesian Agglomeration Coronavirus disease 19 infection Healthy volunteers accepted Slaski Uniwersytet Medyczny w Katowicach Poland 2020-06-22 2021-04-22 2020/ABM /COVID19/0044, EpiSARS2, NCT04627623 Phase Not Applicable Recruiting 1 10 Months 6000 Grzegorz M Brozek, Prof, Jan E Zejda, Prof, Prof. Grzegorz Brożek,, Rafał Trela 2020-11-23
Assessment of Stress, Depression and Anxiety in Healthcare Caring for Patients With COVID-19 Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression, Sleep disorder Beck's Test alone, COPE test alone, Test PSS alone, Test STAI alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Jagiellonian University Poland 2020-07-01 2021-12-31 1072.6120.161.2020, NCT04631497 Phase Not Applicable Recruiting 1 18 Months 100 Tomasz Skladzien, Ph.D. M.D, Tomasz Skladzien, Ph.D. M.D., Tomasz Skladzien, PhD 2020-11-23
Exploratory Phase I Trial of the Active IMP in Healthy Volunteers in Relation to COVID-19 Coronavirus disease 19 infection ivermectin (extended release/sc/BEPO, COVID-19), MedinCell alone Healthy volunteers accepted, Male, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) MedinCell SA MAC Clinical Research UK 2020-09-22 2021-05-31 MDC-TTG-CT-001, NCT04632706 Phase 1 Clinical Recruiting 1 8 Months 24 Chief Development Officer, Joel Richard, L Cheung, P M Leung, R Kelshaw 2020-11-24
An European clinical study to assess RLF-100 in the treatment of patients with COVID-19 induced lung injury Coronavirus disease 19 infection, Lung injury aviptadil (inhaled, sarcoidosis/acute lung injury/acute respiratory distress syndrome associated COVID-19), Relief Therapeutics Holding alone Adrenergic receptor antagonist, VIP receptor agonist Relief Therapeutics Holding AG Syneos Health Inc Europe 2021-03-31 Phase Not Applicable Planned 0 2020-11-19
MEDIC-LAUMC: Managing Endothelial Dysfunction in COVID-19: A Randomized, Controlled Trial at LAUMC Coronavirus disease 19 infection, Dyspnea, Respiratory distress syndrome, Vascular disease anticoagulation therapy alone, Variable regimens including L-arginine , atorvastatin , dexamethasone , folic acid , nebivolol , nicorandil , vitamin C , zinc Beta 1 adrenoceptor antagonist, Beta 3 adrenoceptor agonist, HMG CoA reductase inhibitor, Potassium channel stimulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) LAU Medical Center Lebanon 2020-11-10 2021-05-01 LEBANESE AMERICAN UNIVERSITY, MEDIC-LAUMC, NCT04631536 Phase 0 Clinical Not yet recruiting 1 5 Months 80 Kamal Matli, Matli Kamal, MD 2020-11-23
A phase IIb, confirmatory study of Zofin in the treatment of patients with COVID-19 infection Coronavirus disease 19 infection Zofin alone Organicell Regenerative Medicine 2021-03-31 Phase 2b Clinical Planned 0 2020-11-19
IvermecPrev-Brazil: Study on the effects of using ivermectin to prevent COVID-19 in an adult population in Brazil Coronavirus disease 19 infection ivermectin alone Chloride channel modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidade Federal de Pernambuco University of Toronto Brazil 2020-04-10 2021-06-30 ISRCTN90437126, IVERMECPREV-BRAZIL SCINETN001.2020, IvermecPrev-Brazil Phase 3 Clinical Recruiting 1 14 Months 800 Prof Denia Fittipaldi-Duarte, Prof deCastro 2020-11-24
EAVE II: Early Pandemic Evaluation and Enhanced Surveillance of the coronavirus COVID-19 Coronavirus disease 19 infection vaccine programmes alone Academic and Clinical Centre Office for Research and Development [ACCORD], UK UK 2020-03-01 2021-09-30 EAVE II, IRAS 114474, ISRCTN40292537 Phase Not Applicable Recruiting 2 19 Months 5400000 Prof Sheikh 2020-11-25
Cash transfers to stimulate school re-enrollment among vulnerable adolescent girls in urban informal settlements as Kenya responds to COVID-19 Coronavirus disease 19 infection one-time cash transfer alone Healthy volunteers accepted, Female Population Council - Kenya Bill & Melinda Gates Foundation, Department for International Development, Echidna Giving Kenya 2020-10-02 2021-06-30 ISRCTN12792822, P661 Phase Not Applicable Not yet recruiting 1 8 Months 1700 Dr Austrian 2020-11-25
COVID-19 - Administration of the SARS-CoV-2-Neutralizing Monoclonal Antibody DZIF-10c (Inhalation) Coronavirus disease 19 infection DZIF-10c alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Cologne Boehringer Ingelheim International GmbH, The Clinical Trials Centre Cologne Germany 2020-11-23 2021-06-30 NCT04631705, UNI-KOELN-4370 Phase 1/Phase 2 Clinical Not yet recruiting 1 7 Months 69 Florian Klein, Univ.Prof., Gerd Fätkenheuer, Henning Gruell, Dr. med. 2020-11-23
APEL-COVID: Apelin; ACE2 and Biomarkers of Alveolar-capillary Permeability in SARS-cov-2 (COVID-19) Adult respiratory distress syndrome, Coronavirus disease 19 infection, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universite de Sherbrooke University Hospital, Angers Canada 2020-10-26 2021-12-01 2021-3862-APEL-COVID, APEL-COVID, NCT04632732 Phase Not Applicable Recruiting 1 13 Months 140 Frédéric Chagnon, MSc, Olivier Lesur, MD PhD 2020-11-23
An observational study to evaluate the pharmacokinetics and safety of lopinavir in COVID-19 patients Coronavirus disease 19 infection, SARS coronavirus infection lopinavir + ritonavir alone HIV protease inhibitor CHU De Nantes France Phase Not Applicable Status not specified 1 12 2020-11-19
Physical Activity and the Risk of COVID-19 Infection and Mortality Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry Wonju Christian Hospital South Korea 2014-01-01 2020-07-31 2020AN0292, NCT04631861 Phase Not Applicable Completed 1 79 Months 132069 Dong-Hyuk Cho 2020-11-23
A retrospective, single-center, case-control, comparative analysis on the safety and efficacy of anti-IL6 tocilizumab in patients with COVID-19 Coronavirus disease 19 infection tocilizumab alone Osped Niguarda Ca Granda Phase Not Applicable Status not specified 0 222 2020-11-19
Sleep and Covid19: Sleep Behavior in Athletes During Home Confinement Due to the Covid-19 Outbreak Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs) Istituto Ortopedico Galeazzi Spa Italy 2020-05-22 2021-02-28 NCT04632615, SLEEP&COVID19, Sleep and Covid19 Phase Not Applicable Recruiting 1 9 Months 230 Jacopo Antonino Vitale, PhD, Stefano Borghi, MSc 2020-11-19
PROPEL: Intravenous Zotatifin in Adults With Mild or Moderate COVID-19 Coronavirus disease 19 infection zotatifin alone Eukaryotic initiation factor 4A-I inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of California San Francisco, eFFECTOR Therapeutics Inc Medpace Inc 2020-11-16 2021-07-01 EFT226-0003, NCT04632381, PROPEL Phase 1b Clinical Not yet recruiting 0 7 Months 36 Mark Densel, Neil Sankar, MD, MPH, Rhonda Petsch 2020-11-24
COVID-19 - Administration of the SARS-CoV-2-Neutralizing Monoclonal Antibody DZIF-10c (Infusion) Coronavirus disease 19 infection human monoclonal antibody DZIF-10c alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Cologne Boehringer Ingelheim International GmbH Germany 2020-11-23 2021-06-30 NCT04631666, UNI-KOELN-4288 Phase 1/Phase 2 Clinical Not yet recruiting 1 7 Months 69 Florian Klein, Univ.Prof., Gerd Faetkenheuer, Univ.-Prof., Gerd Fätkenheuer, Henning Gruell, Dr. med. 2020-11-19
A Phase II Clinical Trial of Recombinant Corona Virus Disease-19 (COVID-19) Vaccine (Sf9 Cells) Coronavirus disease 19 infection SARS-CoV-2 vaccine (Sf9 Cell, COVID-19), Jiangsu Province Centers for Disease Control and Prevention alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Jiangsu Province Centers for Disease Control and Prevention, West China Hospital China 2020-11-17 2021-11-18 ChiCTR2000039994, JSVCT099, NCT04640402 Phase 2 Clinical Recruiting 1 12 Months 960 Fanyue Meng, Doctor, Fengcai Zhu, Doctor, Wei Wang 2020-11-24
Evaluation of respiratory Tele-rehabilitation in patient with COVID-19 Coronavirus disease 19 infection Diaphragmatic breathing exercise alone, Incentive spirometry exercise alone, Seated arm reaches alone, Sit to stand squats alone, Standing heel raises alone, Standing marching alone, Wall pushups alone, respiratory tele-rehabilitation alone, video conferencing program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mashhad University of Medical Sciences Iran 2020-11-21 IR.MUMS.NURSE.REC.1399.052, IRCT20200711048077N1 Phase Not Applicable Recruiting 1 60 Ali khorsand vakilzadeh, Fateme Rangani, Mohsen Tafaghodi 2020-11-23
Quality of life in post covid affected patients Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sri Ramachandra University India 2020-11-17 CTRI/2020/11/029188 Phase Not Applicable Not yet recruiting 1 500 Suja Lakshmanan 2020-11-27
Psychological effect of COVID 19 on Positive female patient Anxiety disorder, Coronavirus disease 19 infection, Psychiatric disorder Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Medical Sciences Patna India 2020-11-25 CTRI/2020/11/029200 Phase Not Applicable Not yet recruiting 1 25 Dr Poonam Kumari 2020-11-23
LATTICE: To determine the impact of latent tuberculosis on severity and outcomes in patients with suspected SARS-COV-19 infection Coronavirus disease 19 infection, Mycobacterium tuberculosis infection Interferon gamma release assay alone, Mantoux test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences India 2020-11-30 CTRI/2020/11/029203, LATTICE Phase Not Applicable Not yet recruiting 1 300 Dr Pawan Tiwari, Dr Randeep Guleria, Dr Shweta Bhopale 2020-11-27
A phase III clinical trial of SARS-CoV-2 protein subunit vaccine (COVID-19) in COVID-19 patients Coronavirus disease 19 infection SARS-CoV-2 protein subunit vaccine (COVID-19), Chongqing Zhifei Biological Products/ Institute of Microbiology, Chinese Academy of Sciences alone COVID19 Spike glycoprotein modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Anhui Zhifei Longcom Biopharmaceutical Co Ltd Uzbekistan Phase 3 Clinical Status not specified 1 5000 2020-11-18
An observational study to determine the association of vaccine coverage with the prevalence of SARS-CoV-2 infection Coronavirus disease 19 infection BCG vaccine alone Utano National Hospital Japan Phase Not Applicable Status not specified 1 2020-11-18
A clinical study to assess repurposed niclosamide in the treatment of patients with COVID-19 Coronavirus disease 19 infection repurposed niclosamide (oral/tablet, COVID-19), Hyundai Bioscience/CNPharm alone CNPharm Co Ltd Phase Not Applicable Planned 0 2020-11-18
HERODOTUS: Head and Neck cancers International Covid-19 collaboration Coronavirus disease 19 infection, Head and neck tumor, Nasal cancer, Salivary gland cancer, Thyroid tumor, Viral pneumonia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hellenic Cooperative Oncology Group Emory University, Fondazione IRCCS Istituto Nazionale Tumori, Grupo Español de Tratamiento de Tumores de Cabeza y Cuello, National Cancer Centre of Singapore, The University of Birmingham, University of Queensland, University of Toronto Greece 2020-12-01 2021-06-30 HERODOTUS, HERODOTUS, NCT04632173 Phase Not Applicable Not yet recruiting 1 7 Months 750 Amanda Psyrri, Amanda Psyrri, MD, Evita Fragou, Lisa Licitra, MD 2020-11-19
NUEVA: BCG Vaccination to Prevent COVID-19 Coronavirus disease 19 infection BCG vaccine, Organon alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Henry M Jackson Foundation for the Advancement of Military Medicine Defense Health Agency, Harvard Medical School, US Department of Defense, Uniformed Services University of the Health Sciences US 2020-11-30 2023-04-30 NCT04632537, NUEVA, USUHS.2020-062 Phase 3 Clinical Not yet recruiting 3 29 Months 550 Ansley Adams, BS, Dan Steigelman, MD, David Hrncir, MD, Dutchabond Shaw, RN, Kimberly Murphy, MSN, Marianne Spevak, BSHS, Naomi E Aronson, Thomas G Oliver, Thomas Oliver, MD 2020-11-26
RHEA-COVID19: Effectiveness and Safety of Rhea Health Tone as add-on Therapy for COVID-19 in Hospitalized Adults in Indonesia Coronavirus disease 19 infection Rhea Health Tone alone, Standard of Care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Universitas Padjadjaran PT. Rhea Pharmaceutical Sciences Indonesia, Prodia Clinical Laboratory Indonesia 2020-12-01 2021-02-15 NCT04627519, PHARM-202010.01, RHEA-COVID19 Phase 2 Clinical Not yet recruiting 1 2 Months 69 Haig YH Babikian, Keri Lestari, Keri Lestari, PhD 2020-11-25
High GRP78 Levels in Covid-19 Infection: A Case-Control Study Coronavirus disease 19 infection ELISA kit, Sun Long alone, Serum protein level analysis alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kafkas University Acibadem University, Pamukkale University Faculty of Medicine Turkey 2020-04-16 2020-10-10 CLINICAL-2, NCT04628637 Phase Not Applicable Completed 1 5 Months 144 Ramazan Sbirli, Dr. 2020-11-19
Curaneum 20 for Covid 19 Coronavirus disease 19 infection Curaneum 20 alone, standard management alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) India 2020-12-01 CTRI/2020/11/029166 Phase 3 Clinical Not yet recruiting 1 200 Arunaloke Chakrabarti, Prof Pradip Bhattaharyya 2020-11-23
Study to evaluate the knowledge, attitude and mental health of in-hospital front-line warriors of operation theatre Coronavirus disease 19 infection, Psychiatric disorder Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Government Medical College and Hospital,Chandigarh India 2020-11-20 CTRI/2020/11/029159 Phase Not Applicable Not yet recruiting 1 200 Sukanya Mitra 2020-11-20
Clinical Study Spartan COVID-19 V2 System (Canada Alternate) Coronavirus disease 19 infection Spartan COVID-19 v2 System alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Spartan Bioscience Inc US, Canada 2020-11-30 2021-01-31 NCT04628208, VNV-00635 Phase Not Applicable Not yet recruiting 2 2 Months 60 Tara Linseman 2020-11-19
Covid19-Pain: Musculoskeletal Pain In Patients With COVID-19 Who Have Hospital Care Coronavirus disease 19 infection, Musculoskeletal pain Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fondazione Don Carlo Gnocchi - Onlus Italy 2020-12-01 2021-07-31 COVID19-PAIN, Covid19-Pain, NCT04632355 Phase Not Applicable Not yet recruiting 1 8 Months 100 Jorge H Villafañe, Jorge H Villafañe, Ph.D 2020-11-20
Covid-19 Anxiety And Phobia Levels Of The Parents Anxiety disorder, Coronavirus disease 19 infection, Phobia Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Selcuk University Turkey 2020-05-01 2020-10-15 FARUKCICEKCI, NCT04631172 Phase Not Applicable Completed 1 5 Months 150 Faruk Cicekci 2020-11-20
CMR Findings in COVID-19 Patients Presenting With Myocardial Infarction Coronavirus disease 19 infection, Myocardial infarction cardiac magnetic resonance imaging alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assiut University Egypt 2021-01-01 2023-10-31 CMR IN MYOCARDIAL INFARCTION, NCT04628104 Phase Not Applicable Not yet recruiting 1 34 Months 60 Mohamed Ahmed Abdallah Hamada, hosam hasan, master, mohamed ahmed, Master 2020-11-19
mHealth Intervention for Increasing COVID-19 Prevention Practices With Urban Refugee and Displaced Youth in Uganda Coronavirus disease 19 infection Kukaa Sala mHealth intervention alone, face mask and soap provision alone Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs) University of Toronto Uganda 2021-02-01 2021-09-20 IDRC_COVID, NCT04631367 Phase Not Applicable Not yet recruiting 1 7 Months 404 Carmen H Logie, PhD, Moses Okumu, PhD 2020-11-19
ANCOR: What can the investigators learn from the implementation of a novel point-of-care antigen-based SARS-CoV-2 rapid diagnostic test to screen incoming patients in a large university hospital? (COVID-19) Coronavirus disease 19 infection novel point-of-care antigen-based SARS-CoV-2 rapid diagnostic test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Heidelberg Germany 2020-11-23 ANCOR, DRKS00023584, S-811/2020 Phase Not Applicable Not yet recruiting 1 44 Claudia Denkinger 2020-11-20
Characteristics of COVID-19 Patients in Kazakhstan in Early 2020 Coronavirus disease 19 infection, Respiratory distress syndrome, Sepsis, Septic shock, Viral pneumonia Semey State Medical University Kazakhstan 2020-02-20 2020-12-01 76.29.31_48.04.06-01, NCT04627194 Phase Not Applicable No longer recruiting 1 9 Months 1000 Maiya Goremykina, M.D, C.M.S, Raifa Ivanova, MD, D.M.S., Sergey Yegorov, Ph.D., Yersin Zhunussov, MD, D.M.S. 2020-11-19
Efficacy and safety of pentoxifylline in treatment and recovery of patients with COVID-19 Coronavirus disease 19 infection Variable regimens including hydroxychloroquine , pentoxifylline , sofosbuvir + daclatasvir Phosphoric diester hydrolase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Iran University of Medical Sciences Iran 2020-08-17 IR.IUMS.REC.1399.458, IRCT20170809035597N2 Phase 3 Clinical No longer recruiting 2 86 Azadeh Goodarzi, Azadeh Goodarzi, Simin Almasi 2020-11-20
AntagoBrad-Cov: Evaluation of the effects of bradykinin antagonists on pulmonary manifestations of COVID-19 infections Coronavirus disease 19 infection, Lung disease CE-1145 plus icatibant Bradykinin B2 receptor antagonist, Complement C1s subcomponent inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) GCS Ramsay Santé pour l’Enseignement et la Recherche France 2020-11-12 2020-002225-29, AntagoBrad-Cov, AntagoBrad-Cov Phase 2 Clinical Recruiting 1 45 SAHBANE 2020-11-20
AspCOVID-19 study: Fungal infection of the airways in severe COVID-19 pneumonia Aspergillus infection, Coronavirus disease 19 infection, Viral pneumonia standard laboratory parameters alone, standard microbiological testing alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Technical University of Munich Germany 2020-03-11 2020-07-31 AspCOVID-19 study, ISRCTN14810048 Phase Not Applicable Completed 2 4 Months 32 Dr Lahmer 2020-11-23
Prospective research for early detection of COVID-19 pneumonia using mobile CT vehicle at specialized accommodation facilities Coronavirus disease 19 infection, Viral pneumonia mobile CT vehicle alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Yokohama City University Japan Agency for Medical Research and Development Japan 2020-11-17 UMIN000042477 Phase Not Applicable Recruiting 1 150 Tsuneo Yamashiro 2020-11-19
Japanese health and safety information for international visitors: a randomized controlled trial Coronavirus disease 19 infection sa-chan game alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Human Environments, University of Tokyo Japan Science and Technology Agency Australia, North America, Europe 2020-12-15 UMIN000042483 Phase Not Applicable Not yet recruiting 1 1000 Mariko Nishikawa 2020-11-20
Antiinflammatory and anticoagulative agents in COVID-19 pneumonia treatment Coronavirus disease 19 infection, Viral pneumonia Dexamethasone plus enoxaparin sodium Low molecular weight heparin IM Sechenov Moscow Medical Academy Russian Federation, Europe 2020-04-08 UMIN000042489 Phase Not Applicable Completed 1 157 Petr Tkachenko, Vladimir Ivaashkin 2020-11-19
A retrospective study to analyze the impact of influenza A virus (IAV) exposure on COVID-19 Coronavirus disease 19 infection, Influenza virus A infection oseltamivir alone Exo-alpha sialidase inhibitor Peking University First Hospital China Phase Not Applicable Status not specified 1 70 2020-11-18
Does emergency orthopedic surgery in the pandemic era increase the risk of developing COVID-19? A combined analysis of retrospective and prospective study at a national tertiary hospital in Jakarta, Indonesia Coronavirus disease 19 infection, Surgical procedure orthopedic surgery alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Cipto Mangunkusumo Hospital, University of Indonesia Indonesia, Asia 2020-04-01 UMIN000042453 Phase Not Applicable Completed 2 14 Achmad Kamal, I Wayan Arya Mahendra Karda 2020-11-20
DemStepCare: General practitioner-based dementia care with coordinated cooperation and risk-stratified use of specialized nurses Coronavirus disease 19 infection, Dementia DemStepCare intervention alone Klinikum der Albert-Ludwigs Universitaet Freiburg Dlr Deutsches Zentrum Für Luft- Und Raumfahrt Ev Germany 2019-10-17 2019-14427, DRKS00023560, DemStepCare Phase Not Applicable Recruiting 1 2400 Erik Farin-Glattacker, Teresa Weber 2020-11-20
Clinical profiles and outcomes of COVID patients given with remdesivir: A single centre experience Coronavirus disease 19 infection remdesivir alone COVID19 non structural protein 8 modulator, COVID19 replicase polyprotein 1ab inhibitor, RNA polymerase modulator Southern Philippines Medical Center Philippines 2020-03-01 PHRR201111-003148 Phase Not Applicable Not yet recruiting 1 Ranillo V Gamutan Jr 2020-11-20
Sero-surveillance for Dengue, Chikungunya and COVID Chikungunya virus infection, Coronavirus disease 19 infection, Dengue virus infection Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) International Clinical Epidemiology Network (INCLEN) TRUST India 2020-12-01 CTRI/2020/11/029141 Phase Not Applicable Not yet recruiting 1 5000 Divya Nair, Shikha Dixit 2020-11-20
Role of Heparin inhalation in reducing the duration the patient is breathing with the help of a ventilator Coronavirus disease 19 infection Heparin alone, Standard care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Medical Sciences Patna India 2020-12-01 CTRI/2020/11/029175 Phase 2 Clinical Not yet recruiting 1 58 Shagufta Naaz 2020-11-19
Validation of immune booster potential of Kabasura Kudineer Coronavirus disease 19 infection Kabasura Kudineer alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Central Council for Research in Siddha, Ministry of Ayush India 2020-11-18 CTRI/2020/11/029137 Phase Not Applicable Not yet recruiting 1 100 Dr Aiswarya M Nair, Dr Parameswari RP, Prof SP Thyagarajan 2020-11-19
Difficulties encountered with respiration while providing analgesia for surgeries to patients who had recovered from Covid-19 infection Coronavirus disease 19 infection, General anesthesia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) SRM University India 2020-11-20 CTRI/2020/11/029148 Phase Not Applicable Not yet recruiting 1 50 Dr CR Saravanan, Dr Parameshwaran M 2020-11-19
Use of a new breathing device for covid 19 patients Coronavirus disease 19 infection InVicto alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Royal Brompton Hospital India 2020-11-23 CTRI/2020/11/029146 Phase Not Applicable Not yet recruiting 1 240 Dr Alben Sigamani, Dr Vimal Bharadwaj 2020-11-19
Impact of COVID 19 on Guillain-Barre Syndrome in India Coronavirus disease 19 infection, Guillain Barre syndrome Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences India 2020-12-01 CTRI/2020/11/029143 Phase Not Applicable Not yet recruiting 1 300 Vishnu VY 2020-11-20
Effect of Covid19 work from home on musculoskeletal disorders Coronavirus disease 19 infection, Musculoskeletal disease Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Manipal Academy of Higher Education India 2020-12-01 CTRI/2020/11/029142 Phase Not Applicable Not yet recruiting 1 498 Dr G Arun Maiya, Garima Gupta 2020-11-19
The effects of aromatherapy on the anxiety and sleep quality of the patients with COVID-19 Anxiety disorder, Coronavirus disease 19 infection aromatherapy alone, lavender essential oil (Zardband company) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Kerman University of Medical Sciences Iran 2020-11-05 IR.KMU.REC.1399.423, IRCT20201020049088N1 Phase 2 Clinical Recruiting 1 60 Abbas Pardakhti, Behnaz Bagherian, Mohammad Hossein Mehrolhassani 2020-11-20
TS-COVID: Prevention With Chloroquine in Health Personnel Exposed to Infection With Coronavirus Disease 2019 (COVID-19) Coronavirus disease 19 infection chloroquine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundacion Clinica Valle del Lili Colombia 2020-03-28 2021-02-14 FVL-1567, NCT04627467, TS-COVID Phase 2 Clinical No longer recruiting 1 10 Months 3217 Juan D Velez, MD 2020-11-19
Baseline Vitamin D Deficiency and COVID-19 Disease Severity Coronavirus disease 19 infection, Vitamin D deficiency Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Parkview Medical Center US 2020-10-27 2022-04-14 NCT04628000, PIRB78 Phase Not Applicable Recruiting 1 17 Months 50 Doug Duffee, Doug Duffee, MD, Stephaine Lucas, MD, Stephanie Lucas, MD 2020-11-18
Mothers view on the impact of increased screen time on the overall health of school going children during COVID-19 Coronavirus disease 19 infection survey alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Welcomgroup Graduate School of Hotel Administration India 2020-11-22 CTRI/2020/11/029171 Phase Not Applicable Not yet recruiting 1 261 Humaira Fatima Shah, Mrs Swathi Acharya K 2020-11-18
Efficacy of Yoga Based Self-Management Program for Chronic Pain Coronavirus disease 19 infection, Pain Yoga based self-management alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Aarogyam UK Patanjali Yog Peeth (UK) Trust UK 2020-09-17 2020-11-09 AU0211, NCT04628130 Phase Not Applicable Completed 2 1 Month 42 Deepa Modi, Neha Sharma, Sunita Poddar, Vishwesh Kulkarni 2020-11-18
A phase I/Ii clinical trial of PDS-0203 for the potential prevention of COVID-19 infection Coronavirus disease 19 infection PDS-0203 alone Coronavirus spike glycoprotein inhibitor PDS Biotechnology Corp 2021-06-30 Phase 1/Phase 2 Clinical Planned 0 2020-11-17
Covid19 Antibody prevalence and sustainability. A retrospective, longitudinal, mono-centered, observational study in Covid-19 PCR positive hospital workers Coronavirus disease 19 infection Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Ernst von Bergmann Clinic Germany 2020-11-20 DRKS00023561, S 30(bB)/2020 Phase Not Applicable Recruiting 1 207 Maria Biersack 2020-11-18
Comparison of the Surgical Facemask With the Double-trunk Mask on Oxygenation in COVID-19 Coronavirus disease 19 infection Double-Trunk Mask alone, Surgical Mask alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Clinique Universitaires Saint-Luc Belgium 2020-11-13 2021-11-13 DTM-003, NCT04629989 Phase Not Applicable Recruiting 1 12 Months 27 William Poncin, William Poncin, PT, PhD 2020-11-20
A Smartphone Intervention for Relational and Mental Well Being Coronavirus disease 19 infection, Depression daily text messages alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Washington US 2020-04-04 2020-08-03 NCT04629755, STUDY00009897 Phase Not Applicable Completed 1 4 Months 1765 Jonathan W Kanter, PhD 2020-11-21
A case-control study to assess safety and efficacy of lenzilumab in the treatment of patients with severe COVID-19 and acute respiratory distress syndrome (ARDS) Coronavirus disease 19 infection, Respiratory distress syndrome lenzilumab alone GM-CSF ligand inhibitor, Immunoglobulin G1 modulator, Immunoglobulin kappa modulator Humanigen Inc US Phase Not Applicable Status not specified 1 39 2020-11-17
LAUREL: Chronic Lung Disease and COVID-19: Understanding Severity, Recovery and Rehabilitation Needs Coronavirus disease 19 infection Rehabilitation-focused program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) VA Office of Research and Development US 2021-11-01 2024-10-31 1 I01 RX-003666-01, F3666-R, LAUREL, NCT04628039 Phase Not Applicable Not yet recruiting 1 36 Months 506 John R Kundzins, BS, Kristina A Crothers, MD 2020-11-20
General Psychological Distress, PTSD, and Co-Morbidities in Healthcare Workers Consequent to COVID-19 Acute stress disorder, Coronavirus disease 19 infection, Post traumatic stress disorder Interpersonal Psychotherapy alone, Medical Music alone, Narrative Writing alone, Prolonged Exposure Therapy alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Weill Medical College of Cornell University US 2020-11-30 2021-09-30 20-04021913, NCT04626050 Phase Not Applicable Not yet recruiting 1 10 Months 120 JoAnn Difede, PhD, Mariel Emrich, BS 2020-11-20
PASSION: Proximal Effects of Alcohol on Same-Sex Intimate Partner Violence Acute stress disorder, Coronavirus disease 19 infection CBT Text Messaging alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Georgia State University University at Buffalo US 2020-11-30 2022-09-30 NCT04625465, PASSION, R01AA025995 Phase Not Applicable Recruiting 1 22 Months 480 Dominic J Parrott, Ph.D., Konrad Bresin, Ph.D. 2020-11-19
M3Epilepsy: Making Mindfulness Matter in Children With Epilepsy Coronavirus disease 19 infection, Epilepsy Making Mindfulness Matter (M3) alone Preschool Children (2-5 yrs), Children (6-12 yrs) Lawson Health Research Institute Canadian Institutes of Health Research Canada 2019-12-02 2022-12-20 6558, M3Epilepsy, NCT04020484 Phase Not Applicable Recruiting 1 36 Months 100 Karen Bax, Ph.D., Kathy Nixon Speechley, Ph.D, Kathy Nixon Speechley, Ph.D., Mary Secco, MSc cand. 2020-11-24
Effect of the globally spread Covid-19 on the diet and lifestyle of adults (25 to 60 years) Coronavirus disease 19 infection questionnaire alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Welcomgroup Graduate School of Hotel Administration India 2020-11-23 CTRI/2020/11/029172 Phase Not Applicable Not yet recruiting 1 200 Deeksha Lobo, Jasmine Tamak, Mrs Pallavi Mahesh Shettigar 2020-11-20
What does Covid 19 do to patients with long standing Kidney disease and the impact of treatment on their course in hospital - a tertiary care hospital study Coronavirus disease 19 infection, End stage renal disease hemodialysis alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kasturba Medical College India 2020-12-01 CTRI/2020/11/029173 Phase Not Applicable Not yet recruiting 1 62 Dr B A SHASTRY, MAHAD HASAN KHAN 2020-11-21
Impact of COVID 19 on domestic responsibilities in physicians Coronavirus disease 19 infection questionnaire alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tata Memorial Hospital India 2020-11-30 CTRI/2020/11/029174 Phase Not Applicable Not yet recruiting 1 2000 Sabita Jiwnani 2020-11-19
Lignocaine nebulization in covid pneumonia Coronavirus disease 19 infection, Viral pneumonia lignocaine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute Of Medical Sciences, Rishikesh India 2020-11-20 CTRI/2020/11/029170 Phase 2 Clinical Not yet recruiting 1 60 Dr Praveen Talawar 2020-11-20
A phase II clinical study to assess STI-2099 either as a stand-alone nasal application or as a combination nasal and intravenous administration in both mild and moderate COVID-19 patients Coronavirus disease 19 infection STI-2099 alone Sorrento Therapeutics Inc Phase 2 Clinical Planned 0 2020-11-17
A phase I safety and pharmacokinetic study of STI-2099 in healthy subjects and outpatients with mild COVID-19 disease with or without a simultaneous intravenous injection of COVI-AMG Coronavirus disease 19 infection STI-2099 alone, COVI-AMG plus STI-2099 COVID19 Spike glycoprotein inhibitor Healthy volunteers accepted Sorrento Therapeutics Inc Phase 1 Clinical Planned 0 2020-11-17
A Phase II Clinical Trial of MW-33 Injection in Patients With COVID-19 Coronavirus disease 19 infection MW-33 alone COVID19 Spike glycoprotein inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mabwell (Shanghai) Bioscience Co Ltd 2020-11-30 2021-09-30 MW33-2020-CP201, NCT04627584 Phase 2 Clinical Not yet recruiting 0 10 Months 150 Bei ZHAO, Master, Song LU, Master 2020-11-18
Echo-COVID: Cardiac Performance in Mechanically Ventilated COVID-19 Patients Coronavirus disease 19 infection, Respiratory failure, Viral pneumonia Mindray M9 (Bio-Medical Electronics Co) alone, Philips CX 50 (Philips Healthcare) alone, Vivid i echocardiography system (GE Medical Systems) alone, echocardiography alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Pontificia Universidad Catolica De Chile Clinica Alemana de Santiago, Hospital Barros Luco Trudeau, University of Chile Chile 2020-04-01 2020-08-01 200422002, Echo-COVID, NCT04628195 Phase Not Applicable Completed 1 4 Months 100 Emilio Valenzuela, M.D 2020-11-18
Expanded Evaluation of the Survivorship Wellness Group Program in the Context of COVID-19 and Telehealth Anxiety disorder, Coronavirus disease 19 infection, Depression Survivorship Wellness Group Program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of California San Francisco US 2020-08-31 2023-12-31 20805, NCI-2020-08530, NCT04630015 Phase Not Applicable Recruiting 1 40 Months 250 Alison Chang, Diane Shumay, PhD, Margaret Chesney, MD, Margaret Chesney, PhD, cancertrials@ucsf.edu 2020-11-19
A retrospective cohort study to examine outcomes among patients who were treated anakinra or tocilizumab for COVID-19 -related cytokine storm Coronavirus disease 19 infection anakinra alone, tocilizumab alone Type I IL-1 receptor antagonist University of California Los Angeles US Phase Not Applicable Status not specified 1 93 2020-11-17
Face Masks to Reduce COVID-19 in Bangladesh Coronavirus disease 19 infection Face mask alone, face mask awareness alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Yale University Innovation for poverty action, North South University, Stanford University Bangladesh 2020-11-15 2021-02-28 2000028482, NCT04630054 Phase Not Applicable Recruiting 1 3 Months 450000 Jason Abaluck, PhD, Md. Alamgir Kabir, BA, Mohammad Ashraful Haque, BA, Stephen P Luby, MD 2020-11-19
Effect of Covid-19 on Outcomes of Pregnancy Coronavirus disease 19 infection PCR test alone Healthy volunteers accepted, Female, Young Adults (18-44 yrs) Assiut University Egypt 2020-09-01 2021-12-01 12789, NCT04629001 Phase Not Applicable No longer recruiting 1 15 Months 1000 Armia Michael 2020-11-19
A real-world study to evaluate T-Detect COVID for past infection Coronavirus disease 19 infection T-Detect COVID alone Adaptive Biotechnologies Corp Ospedale San Raffaele, University of Padua Italy Phase Not Applicable Status not specified 1 2020-11-19
COVID-19 Infection Rate in the Construction- and Cleaning Industry Coronavirus disease 19 infection Spirometry alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Arbeitsmedizinischer Dienst der BG BAU GmbH Berufsgenossenschaft der Bauwirtschaft Germany 2020-11-22 BO/40/2020, DRKS00023558 Phase Not Applicable Not yet recruiting 1 3000 Thomas Solbach 2020-11-20
A retrospective case-control study to evaluate the impact of tocilizumab on mortality and/or invasive mechanical ventilation requirement in a cohort COVID-19 patients Coronavirus disease 19 infection Invasive mechanical ventilation alone, tocilizumab alone Hôpital Nord Franche-Comté France Phase Not Applicable Status not specified 1 206 2020-11-17
Verification of stress relief by introducing online visits to the restrictions on visits of COVID-19 Acute stress disorder, Coronavirus disease 19 infection online visit alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Jinseikai Kohnan Hospital Japan 2020-11-16 UMIN000042384 Phase Not Applicable Not yet recruiting 1 100 Hiroshi Yamamoto 2020-11-18
Maternal Attachment and Depression Anxiety Score Evaluation in COVID-19 Positive Pregnant Women Anxiety disorder, Coronavirus disease 19 infection, Depression Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Istanbul Bakirkoy Maternity and Children Diseases Hospital Turkey 2020-08-01 2020-11-20 MATERNALATTACHMENTCOVID, NCT04629638 Phase Not Applicable No longer recruiting 1 3 Months 500 Pınar Yalcin bahat 2020-11-21
RECOVER: Regenerative Medicine for COVID-19 and Flu-Elicited ARDS Using Longeveron Mesenchymal Stem Cells (LMSCs) Adult respiratory distress syndrome, Coronavirus disease 19 infection, Influenza virus infection allogeneic human mesenchymal stem cells (aging frailty/Alzheimer's disease/metabolic syndrome/hypoplastic left heart syndrome), Longeveron alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Longeveron LLC US 2020-07-24 2025-07-31 00-006, NCT04629105, RECOVER Phase 1 Clinical Recruiting 3 60 Months 70 Andrew Quartin, MD, Anthony Oliva, PhD, Carl Shanholtz, MD, Freshta Akbari, MS, Gisel Urdaneta, MD, John P Galliard, MD, Kevin N Ramdas, MD, MPH, Kristopher Deatrick, MD, Mary- Clare Day, RN, BSN, CCRC, Roland Schein, MD, Sunjay Kaushal, MD, PhD 2020-11-20
CODED: Risk Stratification of COVID-19 Patients Discharged From the Emergency Department Coronavirus disease 19 infection chest radiography alone, lung ultrasonosgraphy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Azienda Ospedaliera Citta della Salute e della Scienza di Torino University of Turin Italy 2020-11-01 2021-07-31 CODED, COVID-ED-INTRISK, NCT04629183 Phase Not Applicable Recruiting 5 9 Months 400 Emanuele E Pivetta, MD, PhD, Enrico Lupia, MD, PhD, Franco Aprà, MD, Fulvio Morello, MD, PhD, Giuseppe Lauria, MD, Peiman Nazerian, MD, Stefano Podio, MD 2020-11-19
LAVA: The LAVA (Lateral Flow Antigen Validation and Applicability) Study for COVID-19 Coronavirus disease 19 infection Innova Lateral Flow Device alone, RT-PCR alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) Alder Hey Children's NHS Foundation Trust UK 2020-11-05 2020-11-19 290989, LAVA, NCT04629157 Phase Not Applicable Recruiting 2 400 Beatriz Larru, MD, Christopher Kelly, Laura Rad, Lucy Cooper, Rachel Harwood, MB BS, Richard Kirk 2020-11-19
Evaluation of a new adhesive system for orthodontic braces for a 6-month period Coronavirus disease 19 infection, Tooth disease conventional bracket system (CS) alone, flash-free adhesive system alone, pre-coated bracket system (PS) alone Ondokuz Mayis University Turkey 2018-06-08 2019-06-18 ISRCTN26731749, OMÜ KAEK 2018/416 Phase Not Applicable Completed 2 12 Months 30 Prof Elekdag-Turk 2020-11-26
A phase II trial of BNT-162b2 for the treatment of COVID-19 Coronavirus disease 19 infection BNT-162b2 alone COVID19 Spike glycoprotein modulator Shanghai Fosun Pharmaceutical (Group) Co Ltd China Phase 2 Clinical Not yet recruiting 1 2020-11-17
Double-Blind, Randomized, Placebo-Controlled, Adaptive-Design, Multicenter, Phase III Study to Evaluate the Efficacy and Safety of Fostamatinib in COVID-19 Subjects Coronavirus disease 19 infection fostamatinib disodium alone, standard of care alone Syk tyrosine kinase inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rigel Pharmaceuticals Inc 2020-12-31 2021-10-31 C-935788-061, NCT04629703 Phase 3 Clinical Not yet recruiting 0 10 Months 308 2020-11-24
EST-OBS-OZO-BIOPLA-SARS-COV 2: Observational study benefits rectal ozone therapy and BIOPLA as complementary therapy in convalescent patients SARS-COV-2 Coronavirus disease 19 infection BIOPLA alone, rectal ozone therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Center for Scientific Research, Cuba BioCubaFarma Cuba 2020-06-08 2020-08-15 EST-OBS-OZO-BIOPLA-SARS-COV 2, RPCEC00000342 Phase Not Applicable No longer recruiting 1 2 Months 40 Mario Slim War, Zullyt Zamora Rodriguez 2020-11-20
A clinical trial to evaluate the safety and pharmacokinetics of COVI-AMG in healthy subjects Coronavirus disease 19 infection COVI-AMG alone COVID19 Spike glycoprotein inhibitor Healthy volunteers accepted Sorrento Therapeutics Inc US Phase Not Applicable Not yet recruiting 1 2020-11-17
A retrospective study of zinc sulfate in combination with a zinc ionophore may improve outcomes in hospialized COVID-19 patients Coronavirus disease 19 infection Variable regimens including azithromycin , hydroxychloroquine , zinc sulphate New York University School of Medicine, US US Phase Not Applicable Status not specified 1 932 2020-11-17
Tracheobronchitis in Respiratory Involvement on the Lung SPECT/CT Images of COVID-19 Patients Coronavirus disease 19 infection, Dyspnea, Tracheobronchitis perfusion lung scintigraphy alone, ventilation alone Central Hospital, Nancy, France France 2020-03-11 2020-07-23 2020PI154, NCT04629222 Phase Not Applicable Completed 1 4 Months 10 Pierre Yves MARIE, PhD 2020-11-18
Clinical trial to evaluate superiority of anti-SARS-CoV-2 convalescent plasma versus standard-of-care in hospitalized patients with mild COVID-19 Coronavirus disease 19 infection Fresh frozen plasma alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Hannover Medical School German Federal Ministry of Health Germany 2020-10-19 2020-001936-86, COMET Phase 2 Clinical Recruiting 1 340 Institute of Transfusion Medicine 2020-11-20
A retrospective study of machine learning models that predict the likelihood of critical events and mortality in COVID-19 patients within clinically relevant time windows Coronavirus disease 19 infection machine learning model alone Mount Sinai School of Medicine US Phase Not Applicable Status not specified 1 4000 Benjamin Glicksberg 2020-11-18
NOTICE: A retrospective chart review study,to collect real-world data on the use of Inomax (nitric oxide) gas, for inhalation therapy in patients with respiratory complications associated with the novel coronavirus SARS-CoV-2 (COVID-19) Coronavirus disease 19 infection, Hypoxia, Respiratory disease nitric oxide (inhaled), Ikaria alone Hemoglobin modulator Mallinckrodt plc Pharmerit International NOTICE Phase 4 Clinical Status not specified 0 2020-11-16
IPCO: Prospective, open-label, randomized, controlled, phase IIb clinical study in parallel groups for the assessment of efficacy and safety of immune therapy with COVID-19 convalescent plasma plus standard treatment versus standard treatment alone of subjects with severe COVID-19 Coronavirus disease 19 infection convalescent plasma alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitatsklinikum Erlangen Germany 2020-06-12 2020-002122-82, IPCO, UKER-COV2-01 Phase 2b Clinical Recruiting 1 58 Transfusionsmedizinische Abteilung 2020-11-18
The lying in prone position effect on oxygen saturation in patients in early stage and not intubated having mild to moderate Lung Disease with COVID-19 Coronavirus disease 19 infection, Lung disease, Respiratory distress syndrome, Viral pneumonia Prone positionioning alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) All India Institute of Medical Sciences Patna India 2020-11-16 CTRI/2020/11/029130 Phase Not Applicable Not yet recruiting 1 48 Shagufta Naaz 2020-11-20
A retrospective observational cohort study of clinical characteristics and predictors of survival in adults with coronavirus disease 2019 receiving tocilizumab Coronavirus disease 19 infection tocilizumab alone Henry Ford Health System US Phase Not Applicable Status not specified 1 81 2020-11-17
Effect of COVID-19 on exercise pattern, diet pattern and weight change in athletes Coronavirus disease 19 infection questionnaire alone Healthy volunteers accepted, Young Adults (18-44 yrs) Welcomgroup Graduate School of Hotel Administration India 2020-11-21 CTRI/2020/11/029124 Phase Not Applicable Not yet recruiting 1 336 Rachana, Swathi Acharya 2020-11-18
Covid-19 risk factors among health care workers Coronavirus disease 19 infection Hydroxychloroquine alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Kasturba Medical College India 2020-11-21 CTRI/2020/11/029084 Phase Not Applicable Not yet recruiting 1 172 Cynthia Amrutha Sukumar 2020-11-20
A prospective study on the interobserver variability of COVID-19 Reporting and Data System (CO-RADS) among radiologists in the Philippine General Hospital Coronavirus disease 19 infection CO-RADS alone Philippine General Hospital, University of the Philippines Philippines 2020-08-01 2020-11-10 PHRR201116-003153 Phase Not Applicable Completed 1 3 Months Gerard Eastdon Ochoco 2020-11-17
Characteristics, Risk Factors, and Clinical outcomes of Confirmed Adult COVID Cases admitted in the Intensive Care Unit of Southern Philippines Medical Center from March to December 2020 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Southern Philippines Medical Center Philippines 2020-03-01 2021-12-31 PHRR201116-003143 Phase Not Applicable Not yet recruiting 1 22 Months Dorothy Joy Edulan Bacomo, Jonathan Jasper Ortiz Barnachea 2020-11-20
The Largest Cluster of Covid-19 in Jerantut Coronavirus disease 19 infection Jabatan Kesihatan Negeri Pahang Malaysia 2020-11-05 2020-12-01 57119, NMRR-20-2448-57119 Phase Not Applicable Status not specified 1 Dr ATIRAH BINTI MOHD AZIZUL 2020-11-17
ICED Study: Observational study on impact of Covid-19 on the emergency department (ED) attendance in Malaysia Coronavirus disease 19 infection Universiti Teknologi Mara Malaysia 2020-12-01 2021-05-31 55703, ICED Study, NMRR-20-2445-55703 Phase Not Applicable Status not specified 24 6 Months Dr Mahathar Abdul Wahab, Dr Mohamad Iqhbal Bin Kunji Mohamad, Dr Mohd Amin bin Mohd Mokhtar, Dr Nurul Huda Ahmad, Prof Sabariah Faizah Jamaluddin 2020-11-27
A clinical trial of AT-301 (nasal spray, COVID-19), Atossa Therapeutics for the treatment of covid-9 infection Coronavirus disease 19 infection AT-301 (nasal spray, COVID-19), Atossa Therapeutics alone COVID19 Spike glycoprotein inhibitor Atossa Therapeutics Inc Phase 2 Clinical Planned 0 2020-11-16
A study to evaluate the impact of COVID-19 on patients with cystic fibrosis Coronavirus disease 19 infection, Cystic fibrosis Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Cystic Fibrosis Foundation Belgium, Spain, US, Italy, UK, Netherlands, Brazil, Argentina, Germany, Switzerland, Russian Federation, New Zealand, Canada, Chile, France, Sweden, Ireland, South Africa, Australia Phase Not Applicable Status not specified 19 181 2020-11-17
HCW-Wristband: Colour-Coded Wristband to Monitor COVID-19 Exposure Status for Healthcare Workers On Early Return to Work After a COVID-19 close contact: A Pilot Study Coronavirus disease 19 infection coloured wristband alone Healthy volunteers accepted HOSPITAL QUEEN ELIZABETH II Malaysia 2020-11-30 2021-06-30 56966, HCW-Wristband, NMRR-20-2443-56966 Phase Not Applicable Status not specified 1 7 Months Dr Teoh Eu Vin, Dr. Liew Houng Bang 2020-11-18
Clinical characteristics and outcomes of ventilated COVID-19 patients in Sungai Buloh Hospital Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Sungai Buloh Malaysia 2020-12-01 2021-02-27 54853, NMRR-20-2441-54853 Phase Not Applicable Recruiting 1 2 Months 50 Dr Nor Haliza Binti Zainol Abidin 2020-11-17
To study the Influence of Food habits, Physical activity and knowledge of pregnant mothers on the problems faced in pregnancy, type of delivery and Birth weight of newborn during COVID-19 times Coronavirus disease 19 infection, Pregnancy disorder telephonic counselling alone Female, Young Adults (18-44 yrs) Welcomgroup Graduate School of Hotel Administration India 2020-11-20 CTRI/2020/11/029070 Phase Not Applicable Not yet recruiting 1 300 Anuhitha Paruchuri, Dr Meenakshi Garg, Rasmiya 2020-11-17
Study of heart injury by laboratory investigation in corona positive patients Coronavirus disease 19 infection, Heart injury Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Sardar Vallabh Bhai Patel Hospital India 2020-11-17 CTRI/2020/11/029068 Phase Not Applicable Not yet recruiting 1 200 Dr Vijaysinh Parmar 2020-11-18
A study to look out outcomes of treated COVID-19 patients admitted to a private hospital in Bangalore Coronavirus disease 19 infection, Renal injury Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Columbia Asia India 2020-11-15 CTRI/2020/11/029067 Phase Not Applicable Not yet recruiting 1 100 Girish Namagondlu 2020-11-19
A Case series, retrospective cohort study of experience with tocilizumab in severe COVID-19 pneumonia after 80 days of follow Coronavirus disease 19 infection, Pneumonia tocilizumab alone Hospital General Universitario De Alicante Spain Phase Not Applicable Status not specified 1 236 2020-11-19
LungCOVID: One year follow-ups of Chilean patients with COVID-19 Coronavirus disease 19 infection, Lung injury, Viral pneumonia blood test alone, chest scan alone, lung function test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidad de Concepcion Agencia Nacional de Investigacion y Desarrollo, Chilean government Chile 2020-09-11 2021-07-30 COVID1005, ISRCTN16865246, LungCOVID Phase Not Applicable Recruiting 2 10 Months 250 Dr Daniel Enos, Dr Gonzalo Labarca, Dr Jaime Lastra, Prof Nova-Lamperti 2020-11-19
RECAP: Assessing patients' risk of COVID-19 severe infection: developing a risk prediction score Coronavirus disease 19 infection Covid-19 templates in EMIS and SystmOne alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Imperial College London Economic and Social Research Council, NIHR Imperial Biomedical Research Centre, NIHR Oxford Biomedical Research Center UK 2020-05-15 2021-04-01 IRAS 283024, CPMS 45890, ISRCTN13953727, RECAP Phase Not Applicable Recruiting 3 10 Months 2870 Dr BelenEspinosaGonzalez 2020-11-19
RECOVERY: A clinical trial of Aspirin for the treatment of blood clots in people with COVID-19 Coronavirus disease 19 infection aspirin alone, standard of care alone Nuffield Department of Population Health UK RECOVERY Phase Not Applicable Status not specified 1 2000 Martin Landray, Peter Horby 2020-11-17
SOVEREIGN 01A: Phase I, randomized, double-blind and adaptive study to evaluate the safety, reactogenicity and explore the immunogenicity of different formulations of the Prophylactic Vaccine Candidates against SARS-CoV-2, FINLAY-FR-1 and FINLAY-FR-1A (COVID-19) Coronavirus disease 19 infection FINLAY-FR-1 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Finlay Institute Cuba 2020-10-19 2021-01-31 IFV / COR / 05, RPCEC00000338, SOVEREIGN 01A Phase 1 Clinical Recruiting 1 3 Months 60 Beatriz Moreno Walls, Meiby Rodriguez Gonzalez, Sonia Perez Rodriguez 2020-11-19
An accelerated design, combined, prospective ascending single-dose and two-dose, randomized, placebo-controlled, blinded, first-in-human adaptive study in healthy adults and patients with COVID-19 infection, to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of therapeutic antibody AOD01 Coronavirus disease 19 infection AOD01 alone Healthy volunteers accepted DSO National Laboratories Singapore AOD01-01 Phase 1/Phase 2 Clinical Planned 1 Dr Brendon Hanson, Dr David Lye Chian Boon 2020-11-20
The efficacy and safety of systemic anticoagulation in novel coronavirus pneumonia (COVID-19): A medical records based retrospective cohort study Coronavirus disease 19 infection, Viral pneumonia systemic anticoagulation alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tongji Hospital, Huazhong University of Science and Technology China 2020-09-01 2022-08-31 ChiCTR2000039855 Phase Not Applicable Not yet recruiting 1 24 Months 750 Bian Yi 2020-11-17
A Descriptive Study on the Knowledge, Perceptions, Preferences and Challenges of OBGYNE Surgeons in Using Personal Protective Equipment for COVID-19 Precaution in the Operating Room Coronavirus disease 19 infection Healthy volunteers accepted Philippine General Hospital Philippines 2020-08-24 2020-09-05 PHRR201021-003052 Phase Not Applicable Completed 1 Judith Faye M. Montero 2020-11-19
Correlation of CT severity scoring with clinical classification of disease in COVID-19 positive patients Coronavirus disease 19 infection University of the Philippines Philippines 2020-05-01 2020-08-12 PHRR201021-003070 Phase Not Applicable Completed 1 3 Months Clare Toledo 2020-11-19
MEMORY-COVID: Manganese-Enhanced Magnetic Resonance Imaging of Myocardial injury in COVID-19 Coronavirus disease 19 infection, Heart injury, Myocardial disease, Myocarditis, Systolic dysfunction computed tomography coronary angiography alone, electrocardiography alone, magnetic resonance imaging alone, gadolinium plus manganese Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Edinburgh UK 2020-06-10 2022-06-10 20/NW/0249, MEMORY-COVID, NCT04625075 Phase Not Applicable Recruiting 1 24 Months 40 Shruti Joshi, MBBS, Trisha Singh, BM, Trisha Singh, BM, BMedSci 2020-11-18
PPEDiC: A study of parents views and motivations on presenting to their local pediatric emergency department during the coronavirus pandemic (COVID-19) Coronavirus disease 19 infection Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) University Hospital Lewisham UK 2020-05-04 2020-12-31 IRAS 287536, ISRCTN12833010, PPEDiC Phase Not Applicable Not yet recruiting 3 7 Months 220 Dr Nyirenda, Dr Tina Sajjanhaar 2020-11-18
The effect of balloon-blowing on dyspnea and oxygenation in non-critical adult covid-19 patients Coronavirus disease 19 infection, Dyspnea balloon blowing alone, necessary medication alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Qazvin University Of Medical Sciences Iran 2020-07-22 2020-10-30 IR.QUMS.REC.1399.043, IRCT20201012049010N1 Phase Not Applicable Completed 1 3 Months 90 Mohammad Bargahi, Mohammadali emamjomeh, Seyed Saeed Farzam 2020-11-17
OZO-EST-OBS: Prevalence of positive evolutive PCR in patients with COVID 19 treated with rectal ozone therapy: observational study prospective cohort Coronavirus disease 19 infection Ozone therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) National Center for Scientific Research, Cuba Cuba 2020-08-15 2020-10-25 OZO-EST-OBS, OZO-EST-OBS-01, RPCEC00000341 Phase Not Applicable Completed 1 2 Months 200 Zullyt Zamora Rodriguez 2020-11-17
An Investigation of the impact of Faramir on the clinical symptoms in patients with COVID-19 Coronavirus disease 19 infection faramir containing Salvia officinalis extract (Meem Pharmaceutical Factory) alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Shaheed Beheshti Medical University Iran 2020-11-21 IR.SBMU.MSP.REC.1399.396, IRCT20170315033086N7 Phase 2 Clinical Recruiting 1 128 Minoosh Shabani, Saeed Karima, Somayeh Mahmoodi Baram 2020-11-23
ACCURATE-BL-COVID-19: COVID-19 in Baselland: Validation of Simple and Accurate Tests for COVID-19 Detection, Monitoring and Tracing Coronavirus disease 19 infection LAMP assay alone, NGS diagnostic assay alone, POCT antigen tests alone, crude RNA extraction alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Basel ETH Zurich, Kanton Basel- Landschaft Switzerland 2020-10-24 2021-03-31 2020-01112, ACCURATE-BL-COVID-19, CH20SAVIC2, NCT04625257 Phase Not Applicable Recruiting 1 5 Months 3000 Miodrag Savic, Dr. med. Dr. med. dent. 2020-11-19
SOBERANA 02: Phase I study, open, sequential and adaptive for evaluating the safety, reactogenicity and explore the immunogenicity of the prophylactic Vaccine Candidate FINLAY-FR-2 anti SARS-CoV-2 (COVID-19) Coronavirus disease 19 infection FINLAY-FR-2 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Finlay Institute Cuba 2020-11-02 2021-06-01 IFV/COR/06, RPCEC00000340, SOBERANA 02 Phase 1 Clinical Not yet recruiting 1 7 Months 40 Beatriz, Maria Toledo Romani, Meiby Rodriguez Gonzalez 2020-11-23
MSC-COVID19: Efficacy of Infusions of MSC From Wharton Jelly in the SARS-Cov-2 (COVID-19) Related Acute Respiratory Distress Syndrome Coronavirus disease 19 infection, Multiple organ failure, Respiratory distress syndrome Wharton's jelly mesenchymal stem cells alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Central Hospital, Nancy, France France 2020-11-06 2022-08-06 2020-002772-12, MSC-COVID19, NCT04625738 Phase 2a Clinical Not yet recruiting 1 21 Months 30 Bruno LEVY, MD, PhD, Cecile POCHON, MD, POCHON Cecile, Sebastien GIBOT, MD, PhD, Sébastien GIBOT, MD, PhD 2020-11-18
PROVENT: Phase III, Double-blind, Placebo-controlled Study of AZD-7442 for Pre-exposure Prophylaxis of COVID-19 in Adult Coronavirus disease 19 infection AZD-7442 alone COVID19 Spike glycoprotein inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) AstraZeneca plc Biomedical Advanced Research and Development Authority (BARDA), IQVIA Holdings Inc UK, US 2020-11-17 2021-12-14 D8850C00002, NCT04625725, PROVENT Phase 3 Clinical Not yet recruiting 2 12 Months 5000 AstraZeneca Clinical Study Information Center, Myron Levin, MD 2020-11-18
DMMETCOV19: Metformin Glycinate in Patients With MS or DM2, Hospitalized With COVID-19 and SARS Secondary to SARS-CoV-2 Coronavirus disease 19 infection, Metabolic syndrome X, Non-insulin dependent diabetes metformin glycinate (diabetes/acute respiratory distress syndrome/COVID-19), Laboratorios Silanes alone, standard treatment alone AMP activated protein kinase stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Laboratorios Silanes SA De CV Mexico 2020-11-30 2021-03-31 DMMETCOV19, NCT04626089, SIL-30000-II(1) Phase 3b Clinical Not yet recruiting 1 4 Months 20 Daniel Juarez, BPC, Fausto González-Villagrán, MD, Jorge Gonzalez-Canudas, MD, Nayeli Goreti, Yulia Romero-Antonio, B.S. 2020-11-18
DMMETCOV19-2: Metformin Glycinate, Treatment of Patients With COVID-19 and Severe Acute Respiratory Syndrome Secondary to SARS-CoV-2 Coronavirus disease 19 infection metformin glycinate (diabetes/acute respiratory distress syndrome/COVID-19), Laboratorios Silanes alone, standard treatment alone AMP activated protein kinase stimulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Laboratorios Silanes SA De CV Mexico 2020-07-14 2021-03-31 DMMETCOV19-2, NCT04625985, SIL-30000-II-20(2) Phase 3b Clinical Recruiting 1 8 Months 20 Janet S Aguirre, MD, Janet Silvia M Aguirre, MD, Jorge Gonzalez-Canudas, MD, Paulina Trapaga, MD, Yulia Romero-Antonio, B.S. 2020-11-18
COVecu: Behavior and Experience of Communities Healthcare Professionals Facing the SARS CoV-2 (COVID-19) Epidemic Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-09-17 2021-01-31 AP-HP 200512, COVecu, NCT04625296 Phase Not Applicable Recruiting 1 4 Months 75 Flora DEVOS, Nurse MSC PhD, Flora DEVOS, nurse, Flora DEVOS, nurse Msc PhD, Marie BENHAMMANI 2020-11-13
The Potential of Oral Camostat in Early COVID-19 Disease in an Ambulatory Setting to Reduce Viral Load and Disease Burden Coronavirus disease 19 infection camostat mesylate alone, standard of care alone Serine protease inhibitor, Transmembrane serine protease 2 inhibitor, Trypsin inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitair Ziekenhuis Gent Belgium 2020-11-04 2023-01-01 2020-003475-18, NCT04625114 Phase 2 Clinical Recruiting 1 25 Months 150 Linos Vandekerckhove, Marie-Angélique De Scheerder 2020-11-17
SARCODO: Coagulopathy and Vasculopathy Assessment as a Predictor of the Severity of SARS-CoV-2/COVID-19 Infection Blood clotting disorder, Coronavirus disease 19 infection, Lung disease, Respiratory distress syndrome, Vascular disease Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris Agence nationale de la recherche (ANR) France 2020-06-08 2020-12-31 2020-A01048-31, APHP200521, NCT04624997, SARCODO Phase Not Applicable Recruiting 2 6 Months 1000 David M Smadja, David Smadja, Michaela FONTENAY, Natacha Nohilé 2020-11-18
NO-mediated Vascular Function in Covid-19 Patient Coronavirus disease 19 infection, Viral pneumonia ultrasound system (General Electric Medical Systems) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Istituti Clinici Scientifici Maugeri Spa Sb Universita di Verona Italy 2020-05-30 2020-12-31 ICS MAUGERI 2437 CE, NCT04625036 Phase Not Applicable Recruiting 1 7 Months 30 Mara Paneroni, PT, Paola Baiardi, Math 2020-11-18
A case-report study of a COVID-19 patient presented with psychotic disorder Coronavirus disease 19 infection, Delirium, Respiratory disorder, Viral pneumonia corticoid bolus alone, hydroxychloroquine alone, lopinavir alone, risperidone alone, ritonavir alone, tocilizumab alone 5-HT 2 receptor antagonist, Cytochrome P450 3A4 inhibitor, Dopamine D2 receptor antagonist, HIV protease inhibitor, HIV-1 protease inhibitor Male Universidad De Salamanca Phase Not Applicable Status not specified 0 1 2020-11-13
CHLORO-VID: Hydroxychloroquine for the Treatment of SARS-CoV2 (COVID 19): Pharmacokinetic Study Coronavirus disease 19 infection, Viral pneumonia hydroxychloroquine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire de Toulouse France 2021-01-31 2021-05-31 2020-A01094-35, CHLORO-VID, NCT04625218, RC31/20/0155 Phase Not Applicable Not yet recruiting 1 4 Months 40 Stéphanie RUIZ, PH, Stéphanie RUIZ, ph 2020-11-17
UNITY Global: International Registry of Healthcare Workers Exposed to COVID-19 Patients Coronavirus disease 19 infection SARS-CoV-2 antibody serology testing alone, pharmaco-epidemiological inferential analysis alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Certara Bill & Melinda Gates Foundation, COVID -19 Therapeutics Accelerator, PAREXEL International Zambia, Senegal, Uganda, Kenya, South Africa, Pakistan, Nigeria, Zimbabwe 2020-08-13 2021-10-31 CER-HCW-001, NCT04626076, UNITY Global Phase Not Applicable Recruiting 8 14 Months 10000 Craig Rayner, PharmD, Marta Martinez, PharmD, Roman Casciano, Masters, Zainab Samad, Dr. 2020-11-17
Burnout and resilience among internal medicine physicians in-training in a tertiary government hospital in Manila, Philippines during the COVID-19 pandemic: An exploratory mixed method study Acute stress disorder, Coronavirus disease 19 infection Philippine General Hospital Philippines 2020-04-15 2020-07-30 PHRR201103-003115 Phase Not Applicable Completed 3 3 Months Jhaki A. Mendoza, Maria Rosario M. Bayan, Marvin E. Marquez, Patricia Gregoria V. Mina-Cuano, Paula Isabel G Franco, Paula Isabel Gimena Franco 2020-11-18
Study of Recombinant Protein Vaccine with Adjuvant against COVID-19 in Adults 18 Years of Age and Older Coronavirus disease 19 infection SP-0253 alone COVID19 Spike glycoprotein modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) GlaxoSmithKline plc, Sanofi Pasteur Inc Kenya 2020-12-01 2022-04-30 PACTR202011523101903, VAT00002 Phase 2 Clinical Not yet recruiting 4 17 Months 34520 Fabienne Roche, Tirhani Maluleke, Videlis Nduba 2020-11-17
To study the effect of povidone iodine gargle and nasal drops on disease transmissibility in SARS-CoV-2 infected patients Coronavirus disease 19 infection povidone iodine alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Uttar Pradesh University of Medical Sciences India 2020-11-12 CTRI/2020/11/029063 Phase 3 Clinical Not yet recruiting 1 32 Dr Amit Singh, Dr Naresh Pal Singh, Dr Pranav Sharma 2020-11-17
High chloride level, anemia and severity of COVID-19 Anemia, Coronavirus disease 19 infection, Hyperchloremia Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kasturba Medical College and Hospital India 2020-12-21 CTRI/2020/11/029060 Phase Not Applicable Not yet recruiting 1 60 Vedaghosh Amara 2020-11-17
An Efficacy and Safety Clinical Trial of an Investigational COVID-19 Vaccine (BBV-152) in Adult Volunteers Coronavirus disease 19 infection COVAXIN alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Bharat Biotech International Ltd, Indian Council of Medical Research IQVIA RDS Pty Ltd India 2020-11-25 2022-03-01 BBIL/BBV152-C/2020, BBIL/BBV152-C/2020 Version No: 3.0, CTRI/2020/11/028976, NCT04641481 Phase 3 Clinical Recruiting 24 15 Months 25800 Dr Akshata, Dr Anjan Jyoti Talukdar, Dr Azhar Ali Khan, Dr Chadramani Singh, Dr E Venkat Rao, Dr Laxmi S Kumari, Dr Manish Multani, Dr Meghana Murthy, Dr Mohammad Shameem, Dr P Venugopal, Dr Pajanivel Ranganadin, Dr Parul Bhatt, Dr Prabhakar Reddy, Dr Priti Meshram, Dr Raghavendra Gumashta, Dr Sagar Vivek Redkar, Dr Sanjay Kumar Rai, Dr Savita Verma, Dr Savita Verma, MD, Dr Shiva Narang, Dr Simmi Dube, Dr Suman Kanungo, Dr T S Selvavinayagam, Dr Tapan Kumar Saikia, Dr. N.T. Awad, Dr.V.Krishna Mohan, DrAnil Kumar Pandey 2020-11-27
Study to assess the impact of COVID 19 infection on pulmonary function tests in children Coronavirus disease 19 infection Spirometry alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Maulana Azad Medical College India 2020-11-20 CTRI/2020/11/029058 Phase Not Applicable Not yet recruiting 1 100 Dr Romit Saxena 2020-11-18
A study to assess the overall dietary practices among young and middle-aged adults pre and during COVID times Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Welcomgroup Graduate School of Hotel Administration India 2020-11-20 CTRI/2020/11/029041 Phase Not Applicable Not yet recruiting 1 317 Dr Meenakshi Garg, Kritthika Gonella, Sudeepti Pramod Nayak 2020-11-17
Can combination of Haldi, Pomegranate and Zinger extract tablets help in reducing duration of hospital stay of mild to moderate COVID-19 patients Coronavirus disease 19 infection Dantabija + Haridra + Zingiber officinale chewable tablet alone, Standard treatment alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Alchem Phytoceuticals All India Institute of Medical Sciences Patna India 2020-10-19 CTRI/2020/11/029038 Phase 3 Clinical Not yet recruiting 1 100 Dr Yogesh Kumar 2020-11-24
Multisystemic inflammatory syndrome in children (MIS-C) in COVID pandemic Coronavirus disease 19 infection, Inflammatory disease Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs) Institute of Child Health and Hospital for Children, Madras Medical College India 2020-11-29 CTRI/2020/11/029061 Phase Not Applicable Not yet recruiting 1 200 Dr V Poovazhagi, Prof Dr S Elilarasi 2020-11-17
ReCOVer: A study to identify the rehabilitation need in post-discharge COVID-19 survivors Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences India 2020-11-16 CTRI/2020/11/029036, ReCOVer Phase Not Applicable Not yet recruiting 1 384 Raktim Swarnakar, S L Yadav 2020-11-18
Biological E’s novel Covid-19 vaccine of SARS-CoV-2 for protection against Covid-19 disease Coronavirus disease 19 infection RBD-specific protein subunit vaccine (COVID-19), Biological E alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Biological E Ltd India 2020-11-16 BECT062/Covid-19-phase-I&II/CTP-01Ver: 1.1, CTRI/2020/11/029032 Phase 1/Phase 2 Clinical Recruiting 5 360 Dr A Venkateshwar Rao, Dr Chandramani Singh, Dr Puneet Misra, Dr Shiv Narang, Dr Venugopal, DrSubhash Thuluva, DrTSA Kishore 2020-11-20
Blood Glucose Management in Diabetic COVID-19 Patients Coronavirus disease 19 infection, Diabetes mellitus Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sardar Vallabh Bhai Patel Hospital India 2020-11-20 CTRI/2020/11/029059 Phase Not Applicable Not yet recruiting 1 100 Dr Janakkumar R Khambholja, Dr Suhag B Patel 2020-11-17
Measurement of nutritional and health status of Beedi workers before and during COVID times Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Welcomgroup Graduate School of Hotel Administration India 2020-11-20 CTRI/2020/11/029042 Phase Not Applicable Not yet recruiting 1 160 Dr Meenakshi Garg, Nithin, Shwetha Kotian 2020-11-18
Effect of corona virus disease on the mental state of anesthesiologists in India Coronavirus disease 19 infection, Psychiatric disorder Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Government Medical College and Hospital,Chandigarh India 2020-11-15 CTRI/2020/11/029040 Phase Not Applicable Not yet recruiting 1 383 Dr Sanjeev Palta, Kompal Jain 2020-11-15
The performance of a novel ultra-rapid diagnostic test in the detection of COVID 19, an observational and case controlled study Coronavirus disease 19 infection ASU CV19 device alone Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Canary Health Inc India 2020-11-18 CTRI/2020/11/029037 Phase Not Applicable Not yet recruiting 1 750 Prof Ashok Rattan 2020-11-16
Compare oxygen saturation from pulse oximetry and ABG in COVID-19 patients in ICU/HDU Coronavirus disease 19 infection pulse oximetry alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Rajarajeswari Medical college and Hospital India 2020-11-15 CTRI/2020/11/029035 Phase Not Applicable Not yet recruiting 1 100 Nadia Rose, Ramya B Sriram 2020-11-16
Multicentric, observational study on Pediatric Multisystem Inflammatory Syndrome (PMIS) related to Covid-19 Coronavirus disease 19 infection, Inflammatory disease Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Sir Ganga Ram Hospital India 2020-11-19 CTRI/2020/11/029030 Phase Not Applicable Not yet recruiting 8 100 Dr Bharat Mehra, Dr Chandrashekhar, Dr Dhiren Gupta, Dr Mukul Pandey, Dr Nameet Jerath, Dr Rachna Sharma, Dr Swati Kalra, Dr Vinamra Manocha 2020-11-16
A pilot study to determine health concerns developed during COVID-19 pandemic in childhood cancer survivors and siblings of Tata Memorial Hospital, who are now grown up adults Cancer, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tata Memorial Hospital India 2020-11-12 CTRI/2020/11/029029 Phase Not Applicable Not yet recruiting 1 100 Dr Maya Prasad 2020-11-15
An open-label observational study on post covid complications and radiological pattern changes on those patients treated with ZingiVir-H Coronavirus disease 19 infection ZingiVir-H alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Pankajakasthuri herbal research foundation India 2020-11-15 CTRI/2020/11/029025 Phase 2 Clinical Recruiting 1 60 Dr J Hareendran Nair, Dr Shan Sasidharan, DrJHareendran Nair 2020-11-17
An online survey to compare the diet and physical activity management before and during COVID and how it is affected by education, occupation and income in people with diabetes belonging to middle and upper socioeconomic classes Coronavirus disease 19 infection, Non-insulin dependent diabetes Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Welcomgroup Graduate School of Hotel Administration India 2020-11-20 CTRI/2020/11/029009 Phase Not Applicable Not yet recruiting 1 200 DrMeenakshi Garg, Pooja M, Susan Maria 2020-11-16
A randomized, open-label, phase IV monocentric study evaluating the clinical effect of oral immunomodulatory therapy with IMUNOR in patients with moderate COVID-19 disease Coronavirus disease 19 infection Imunor alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Thomayerova Teaching Hospital Czech Republic 2020-002497-27, KFJ-2020-01_IMUNOR Phase 4 Clinical Recruiting 1 60 Skopek -trial coordinator 2020-11-17
Signs and symptoms and outcome of babies < 28 days age admitted during pandemic in a only COVID-19 hospital in North India Coronavirus disease 19 infection Newborn Infants (up to 5 months) Maulana Azad Medical College India 2020-11-17 CTRI/2020/11/029007 Phase Not Applicable Not yet recruiting 1 1000 Dr Ajay Kumar, Dr Ashish Jain 2020-11-16
Radiological And Laboratory Tests Corelation With Clincial Severity Of COVID19 Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sardar Vallabhbhai Patel Institute of Medical Science and Research (SVPIMSR) India 2020-11-16 CTRI/2020/11/029004 Phase Not Applicable Not yet recruiting 1 100 Dr Janakkumar R Khambholja, Dr Juhi Patel 2020-11-24
Long-term lung problem of children who were affected by corona virus Coronavirus disease 19 infection Spirometry alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs) Christian Medical College, Vellore, India India 2020-11-16 CTRI/2020/11/029026 Phase Not Applicable Not yet recruiting 1 100 Dr P Madhan Kumar 2020-11-15
To assess the impact of COVID-19 on the Diet, lifestyle and physical activity of IT employees (20 to 30 years) Acute stress disorder, Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs) Welcomgroup Graduate School of Hotel Administration India 2020-11-20 CTRI/2020/11/029012 Phase Not Applicable Not yet recruiting 1 300 Dr Meenakshi Garg, Koilakonda Sreebhavya, Shivani Endabetla 2020-11-15
To study the overall impact of consumption of non-alcoholic beverages on working from home adults, pre and during COVID times Acute stress disorder, Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Welcomgroup Graduate School of Hotel Administration India 2020-11-20 CTRI/2020/11/029008 Phase Not Applicable Not yet recruiting 1 295 Dalia V R, Dr Meenakshi Garg, Shreya Majumdar 2020-11-12
KAP: Survey of Knowledge, Attitudes and Practices towards Covid-19 Pandemic Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over), Asian Ancestry Tata Memorial Hospital India 2020-11-20 CTRI/2020/11/029006, KAP Phase Not Applicable Not yet recruiting 1 1000 Dr Pabashi Poddar 2020-11-12
Evaluation of the effect of interferon beta-1b in the treatment of COVID-19 Coronavirus disease 19 infection Variable regimens including hydroxychloroquine , interferon beta-1b, Iran Pharmaceutical Company , lopinavir + ritonavir HIV protease inhibitor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Dezful University of Medical Sciences Iran 2020-09-22 IR.DUMS.REC.1399.031, IRCT20200921048786N1 Phase 3 Clinical Recruiting 1 82 Leila Masoudi Yekta 2020-11-15
Message Fatigue_COVID-19 Coronavirus disease 19 infection, Psychiatric disorder Online Survey alone Healthy volunteers accepted Institute for Health Behavioural Research (IHBR) Malaysia 2020-11-12 2021-11-11 57105, NMRR-20-2434-57105 Phase Not Applicable Status not specified 1 12 Months Mr Albeny ak Joslyn Panting, Norbaidurah binti Ithnain 2020-11-12
Correlation of Chest CT findings to the Clinical Outcomes and Final Case Classification of COVID-19 patients admitted at a tertiary hospital in the Philippines Coronavirus disease 19 infection CT scan alone Philippine General Hospital 2020-06-28 2020-08-31 PHRR201023-003084 Phase Not Applicable Completed 0 2 Months Jeffrey P. Apo 2020-11-15
MMD-HP: Moral Distress among Healthcare Professionals in Malaysia during the COVID-19 Pandemic Coronavirus disease 19 infection, Psychiatric disorder Healthy volunteers accepted HOSPITAL SERI MANJUNG Malaysia 2020-12-01 2021-02-28 56862, MMD-HP, NMRR-20-2433-56862 Phase Not Applicable Not yet recruiting 9 3 Months 660 Chiew Shoen Chuen, Dr Sheila Gopal Krishnan 2020-11-17
COPOT: Ocular Trauma Trends During Covid-19 Pandemic Coronavirus disease 19 infection, Ocular disease Hospital Ampang Malaysia 2020-11-23 2020-12-14 57109, COPOT, NMRR-20-2422-57109 Phase Not Applicable Status not specified 1 Dr Timothy Liew Khai Wing 2020-11-18
A Study of Self-risk Behavioral Assessment of Covid-19 Disease Among Sabah State Residents Coronavirus disease 19 infection Self-risk Behavioral Assessment alone National Institutes of Health Malaysia Malaysia 2020-11-13 2020-12-01 57137, NMRR-20-2415-57137 Phase Not Applicable Status not specified 1 Mr Kamarul Zaman bin Salleh 2020-11-12
Prevalence of Right Ventricular Dysfunction and Its Association with COVID-19 Clinical Outcome: A Meta-Analysis Coronavirus disease 19 infection, Heart disease, Pulmonary artery hypertension Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universitas Airlangga Indonesia 2020-11-11 UMIN000042424 Phase Not Applicable Not yet recruiting 1 1000 Eka Mulia 2020-11-15
Providing gold standard continuous medical education to combat COVID-19 Coronavirus disease 19 infection continuous medical education alone Healthy volunteers accepted Universiti Putra Malaysia Malaysia 2020-12-01 2021-05-31 57152, NMRR-20-2410-57152 Phase Not Applicable Not yet recruiting 1 6 Months Dr. Navin Kumar A/L Devaraj 2020-11-17
Prevention of Disease by SARS-CoV-2 (COVID-19) by Pre-Exposure Prophylaxis of Emtricitabine / Tenofovir disoproxil and Hydroxychloroquine in healthcare personnel: Randomized, Placebo-Controlled Clinical Trial Coronavirus disease 19 infection Variable regimens including Hydroxychloroquine , emtricitabine , tenofovir disoproxil fumarate DNA polymerase inhibitor, HIV-1 reverse transcriptase inhibitor, Nucleoside reverse transcriptase inhibitor Instituto Nac De Ciencias Medicas Y Nutricion Salvador Zubiran Mexico 3419 Phase 3 Clinical Status not specified 2 2020-11-15
Evaluating the effects of Adalimumab in patients with acute respiratory distress syndrome caused by COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome Variable regimens including Lopinavir/Ritonavir (Hetero Labs Limited) , adalimumab , interferon b1a TNF alpha ligand inhibitor, TNF binding agent Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Shahid Beheshti University of Medical Sciences, Laser Application in Medical Sciences Research Center Iran 2020-08-06 IR.SBMU.NRITLD.REC.1399.154, IRCT20151227025726N23 Phase 2/Phase 3 Clinical No longer recruiting 1 60 Atefeh Fakharian, Farzaneh Dastan, Zahra Mirshafiei Langari 2020-11-18
Covid-19 Infection and New Onset Type 1 Diabetes Coronavirus disease 19 infection, Insulin dependent diabetes Mixed-meal tolerance test alone, SARS-Cov-2 antibody test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital of South West Jutland Aarhus University Hospital, Steno Diabetes Center, Steno Diabetes Center Nordjylland, Steno Diabetes Center Odense Denmark 2020-11-01 2023-10-30 NCT04623697, S-20200119 Phase Not Applicable Recruiting 1 35 Months 600 Claus B Juhl, Claus B Juhl, MD PhD, Claus B Juhl, MD, PhD, Morten Bjerregaard-Andersen, MD PhD, Morten Bjerregaard-Andersen, MSc, PhD 2020-11-17
Melanoma Patients’ and Clinicians’ Satisfaction with Telehealth During COVID-19 Coronavirus disease 19 infection, Melanoma online survey alone, telehealth alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Melanoma Institute Australia Australia 2020-11-27 2021-01-01 ACTRN12620001167954p Phase Not Applicable Not yet recruiting 3 1 Month 100 Dr Iris Bartula 2020-11-17
The adequacy of user seal checking for N95 respirators compared to formal fit testing, a multicentered, observational study Coronavirus disease 19 infection 3M N95 Healthcare Particulate Respirator alone, Halyard Fluidshield N95 Particulate Filter Respirator alone, Surgical Mask 1860 Regular alone, Surgical Mask Regular alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Epworth HealthCare Australia 2020-05-29 2020-11-30 ACTRN12620001193965, U1111-1254-8633 Phase Not Applicable Recruiting 5 6 Months 187 Dr Helen Cass, Dr Jonathan Barrett 2020-11-12
Inroads: An open, naturalistic trial of the Inroads program, an internet-delivered early intervention to reduce anxiety and alcohol use among young people Alcoholism, Coronavirus disease 19 infection, Generalized anxiety disorder, Social phobia automated email and text reminders alone Adolescents (13-17 yrs), Young Adults (18-44 yrs) University of Sydney Australian Government Department of Health and Ageing Australia 2020-11-20 2022-06-20 ACTRN12620001195943, Inroads Phase Not Applicable Not yet recruiting 8 19 Months 541 Dr Lexine Stapinski 2020-11-17
A Pilot Study to Assess Safety and Efficacy of SIR1-365 in Patients With Severe COVID-19 Cardiovascular disease, Coronavirus disease 19 infection, Renal injury, Respiratory distress syndrome SIR1-365 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sironax USA 2020-12-15 2021-12-15 NCT04622332, SIR365-US-101 Phase 1 Clinical Not yet recruiting 0 12 Months 60 Simon Li, MD, PhD 2020-11-13
INSPIRE: Intravenous Infusion of CAP-1002 in Patients With COVID-19 Coronavirus disease 19 infection CAP-1002 alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Capricor Inc, Capricor Therapeutics Inc US 2020-11-15 2021-06-30 CAP-1002-COVID-19-02, INSPIRE, NCT04623671 Phase 2 Clinical Recruiting 2 7 Months 60 David Brabham, MD, Megan Hazelrigg, Oren Friedman, MD, Tracey S Early, BS, MA, CCRP 2020-11-25
The relationship between COVID-19 Infection and new onset and prognosis of vasospastic angina: Multicenter, prospective study Angina, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Yokohama City University Yokohama City University Medical Center Japan 2020-07-10 UMIN000042248 Phase Not Applicable Recruiting 1 300 Jin Kirigaya, Yasushi Matsuzawa 2020-11-12
Efficacy of Vitamin D Treatment in Mortality Reduction Due to COVID-19 Coronavirus disease 19 infection, Viral pneumonia, Vitamin D deficiency Hidroferol alone Investigation Institute Bioaraba Fundacion Eduardo Anitua Spain 2020-11-09 2021-11-09 NCT04621058, VITD Phase 3 Clinical Recruiting 2 12 Months 108 Joaquin Durán, Joaquín Durán Cantolla 2020-11-15
TEMPO: Telemedical psychiatry and psychotherapy for children and adolescents during the Covid-19 pandemic: feasibility, acceptance, satisfaction and pandemic-specific mental stress Acute stress disorder, Coronavirus disease 19 infection Telemedicine psychotherapy alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) University of Cologne Charite Universitaetsmedizin Berlin, Charité Campus Virchow-Klinikum, University Hospital RWTH Aachen, University of Gottingen Germany 2020-12-01 20-1537, DRKS00023525, TEMPO, U1111-1260-8886 Phase 4 Clinical Not yet recruiting 1 300 Carolina Habbel, Manfred Döpfner, Stephan Bender 2020-11-12
CARDIO-COVID: Prognostic and Clinical Impact of Cardiovascular Involvement in Patients With COVID-19 Coronavirus disease 19 infection, Myocardial disease cardiopulmonary exercise test alone, cardiovascular magnetic resonance imaging alone, chest computerized tomography scan alone, electrocardiogram analysis alone, transthoracic echocardiogram analysis alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Istituto Clinico Humanitas Centro Cardiologico Monzino Spa - Irccs, IRCCS Policlinico San Donato, Istituti Clinici Scientifici Maugeri Spa Sb, Istituto Auxologico Italiano Italy 2020-10-01 2021-10-01 CARDIO-COVID, CARDIOCOVID, NCT04624503 Phase Not Applicable Recruiting 5 12 Months 500 Gianluigi Condorelli, Prof, Giulio Stefanini, Giulio Stefanini, Prof, Giulio Stefanini, Prof., Luigi Badano, Prof., Marco Guazzi, Prof, Piergiuseppe Agostoni, Prof., Sivlia Priori, Prof.ssa 2020-11-12
PIVOT With MI: Presumptively Initiating Vaccines and Optimizing Talk With Motivational Interviewing Coronavirus disease 19 infection motivational interviewing intervention (PIVOT with MI) alone Newborn Infants (up to 5 months) University of Colorado at Denver and Health Sciences Center Eunice Kennedy Shriver National Institute of Child Health & Human Development, National Institutes of Health, Portland State University, Seattle Children's Hospital, The Childrens Mercy Hospital, University of Missouri, University of Washington US 2019-09-01 2023-07-31 17-1274, 1R01HD093628-01A1, NCT03885232, PIVOT With MI Phase Not Applicable Recruiting 2 47 Months 1000 Douglas Opel, MD, MPH, Sean O'Leary, MD, MPH 2020-11-11
A clinical trial of MP-1032 (inhalation, COPD), MetrioPharm for the treatment of covid-19 Coronavirus disease 19 infection MP-1032 (inhalation, COPD), MetrioPharm alone Superoxide dismutase stimulator MetrioPharm AG Phase 2 Clinical Planned 0 2020-11-27
CovIdentify: Using Smart Watches to Detect and Monitor COVID-19 Coronavirus disease 19 infection Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Duke University US 2020-04-02 2022-02-01 CovIdentify, NCT04623047, PRO00106404 Phase Not Applicable Recruiting 1 22 Months 100000 Chris Woods, Jessilyn Dunn, Ryan Shaw 2020-11-13
Neurocognitive Functions of Recovered COVID-19 Patients Coronavirus disease 19 infection, Inflammatory disease, Psychiatric disorder Trier Social Stress Test alone, oral calculation test alone, speech test alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) National Institute on Drug Dependence The Sixth Hospital of Peking University (Institute of Mental Health), Wuhan Wuchang Hospital China 2020-07-10 2020-12-10 NCT04622748, NIDD-2020-NEUROCOGNITION Phase Not Applicable Recruiting 1 5 Months 160 Guofu Huang, Dr, Lin Lu, Dr., Ping Wu, Dr. 2020-11-15
A Virtual Prospective Study Exploring Activity Trackers and COVID-19 Infections Coronavirus disease 19 infection Empatica E4 alone, Garmin vivosmart 4 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Evidation Health Inc Bill & Melinda Gates Foundation, Biomedical Advanced Research and Development Authority (BARDA), Eli Lilly & Co, US Department of Defense, Vir Biotechnology Inc US 2020-11-30 2021-05-31 COVID SIGNALS, NCT04623138 Phase Not Applicable Not yet recruiting 1 6 Months 950 Ernesto Ramirez, PhD, Joyce HN Nortey, MPH, MSBH, Luca Foschini, PhD 2020-11-13
Exercise Influence on COVID-19 Coronavirus disease 19 infection physical exercise alone Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Universidad De Salamanca Spain 2020-12-04 2021-04-04 08112020, NCT04624048 Phase Not Applicable Not yet recruiting 1 4 Months 30000 CARLOS MARTIN-SANCHEZ, DOCTOR 2020-11-14
Thromboprophylaxis for Patients in ICU With COVID-19 Coronavirus disease 19 infection, Thrombosis low molecular weight heparin alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto de Investigacion Sanitaria La Fe Clinica Universidad de Navarra, Hosp Univ & Politecn La Fe, Hospital Clinic of Barcelona, Hospital Universitario Doctor Peset, Hospital de Cruces, Hospital de Sant Joan Despi Moises Broggi, La Paz University Hospital (Madrid) Spain 2020-03-01 2020-11-30 NCT04623177, REGCOVID-19 Phase Not Applicable No longer recruiting 31 9 Months 950 Raquel Ferrandis, MD 2020-11-13
Clarithromycin Versus Azithromycin in Treatment of Mild COVID-19 Infection Coronavirus disease 19 infection clarithromycin alone, symptomatic treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) South Valley University Egypt 2020-04-01 2020-07-30 NCT04622891, SVU-MED-CHT019-420860 Phase 2 Clinical Completed 1 3 Months 300 Alaa Rashad, MD 2020-11-14
Clinical Role of Testosterone and Dihydrotestosterone and Which of Them Should be Inhibited in COVID-19 Patients - A Double-edged Sword? Coronavirus disease 19 infection, Respiratory failure 13-cis retinoic acid plus testosterone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Kafrelsheikh University Egypt 2020-11-30 2021-12-31 NCT04623385, SARS -2 Phase 4 Clinical Not yet recruiting 1 13 Months 1000 Mahmoud Elkazzaz, B.Sc in Biochemistry, Mahmoud Ramadan mohamed Elkazzaz 2020-11-14
RIVERSIDE: Evaluation of the use of video consultation in rheumatology in the context of the COVID-19 pandemic Coronavirus disease 19 infection video consultation alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Universitätklinikum Düsseldorf Germany 2020-11-15 DRKS00023430, IT-TEMP-36, RIVERSIDE Phase Not Applicable Not yet recruiting 1 300 Jutta Richter 2020-11-13
PROFACT-01: An Outpatient Study Investigating Non-prescription Treatments for COVID-19 Coronavirus disease 19 infection chlorine dioxide aqueous solution alone, zinc acetate alone, Variable regimens including Lactoferrin , chlorine dioxide aqueous solution , famotidine , green tea extract , zinc acetate Histamine H2 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Pakistan 2020-11-09 2021-01-31 NCT04621149, PROFACT-01, PROFACT-01 Phase 2 Clinical Not yet recruiting 1 2 Months 120 Jonathan Murphy, MD, MD(H), Mitchell B Liester, MD 2020-11-14
Longitudinal COVID-19 Antibody Testing in Indiana University Undergraduate Students Coronavirus disease 19 infection SARS-CoV-2 IgM/IgG serological test alone, SARS-CoV-2 rapid assay kit (colloidal gold) alone, personal protective behavior alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Indiana University US 2020-09-14 2020-12-31 2008293852, NCT04620798 Phase Not Applicable No longer recruiting 1 3 Months 1700 Molly Rosenberg, PhD 2020-11-15
Effectiveness and safety of plasma convalescent therapy in patients with COVID-19 Coronavirus disease 19 infection convalescent plasma alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ministry of Research and Technology Indonesia 2020-04-26 2020-12-13 003, ISRCTN16842454 Phase 2 Clinical Recruiting 1 7 Months 5 Dr Santosa 2020-11-14
CCP-Cancer UK: Companion study to educate and inform practice and guidelines regarding COVID-19 infection in cancer patients Cancer, Coronavirus disease 19 infection Aged Adults (65-79 yrs), Elderly Adults (80 and over) The Clatterbridge Cancer Centre NHS Foundation Trust Clatterbridge Cancer Research Trust, National Institute for Health Research (NIHR), United Kingdom Research & Innovation UK 2020-08-11 2022-08-24 CCP-Cancer UK, CPMS 46602, IRAS 285044, ISRCTN15019599 Phase Not Applicable Recruiting 2 24 Months 9000 Dr Coordinator 2020-11-18
Pilot, Feasibility Study of Remote Problem Management Plus for Adults Affected by COVID-19 (PM+) Coronavirus disease 19 infection, Psychiatric disorder Problem Management Plus low-intensity psychological intervention alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) New School University George Washington University US 2020-11-30 2021-09-30 2020-91-PM+, NCT04617262 Phase Not Applicable Not yet recruiting 1 10 Months 100 Adam Brown, PhD, Brandon Kohrt, MD, PhD, Kendall Pfeffer, MEd, MA 2020-11-14
TTTC: Taking Time to Connect: A Study of Programs for Hispanic Mothers Diagnosed With Cancer and Their Children Cancer, Coronavirus disease 19 infection Conexiones telephone sessions alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), European Ancestry New Mexico State University Fred Hutchinson Cancer Research Center, National Cancer Institute, University of Washington US 2019-04-16 2021-08-31 17894, NCT03951454, TTTC Phase Not Applicable Recruiting 3 28 Months 156 Frances M Lewis, PhD, Rebecca Palacios, PhD 2020-11-14
A Pilot Study on Efficacy and Safety of Ayurveda Combination in Patients With Mild-to-Moderate COVID-19 Coronavirus disease 19 infection Shanshamani Vati Plus alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Aarogyam UK All India Institute of Ayurveda, Government of India, Ministry of Ayush, Warwick University UK 2020-10-08 2020-11-03 AU/WU/ 06, NCT04621903 Phase Not Applicable Completed 1 26 Dipa Modi, Neha Sharma, Tanuja Nesari, Vishwesh Kulkarni 2020-11-20
plasmApuane CoV-2: Efficacy and Safety of Immune Covid-19 Plasma in Covid-19 Pneumonia in Non ITU Patients Coronavirus disease 19 infection, Viral pneumonia immune plasma infusion alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) L'Azienda USL Nord Ovest Italy 2020-05-15 2020-12-31 ATNONORDOVEST, NCT04622826, plasmApuane CoV-2 Phase 2 Clinical Recruiting 1 7 Months 50 Antonella Vincenti, Mirko lombardi, antonella vincenti, mirko lombardi 2020-11-14
Mental Health in Communities Affected by COVID-19 in Uganda Coronavirus disease 19 infection, Drug dependence, Generalized anxiety disorder, Major depressive disorder, Post traumatic stress disorder, Psychiatric disorder psycho-education intervention alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Makerere University Uganda 2020-11-01 2021-07-30 INTEGRATION OF MENTAL HEALTH, NCT04616989 Phase Not Applicable Not yet recruiting 1 8 Months 840 Dickens Akena, PhD 2020-11-13
Orthopedic Conservative Treatment in the Time of Covid-19 Pandemic Bone injury, Coronavirus disease 19 infection orthopedic conservative treatment alone Elderly Adults (80 and over) Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization Turkey 2020-03-11 2020-12-01 NCT04623346, TREATMENT IN THE TIME OF COVID Phase Not Applicable No longer recruiting 2 8 Months 262 Bulent KARSLIOGLU 2020-11-18
Efficacy and Safety of Acetyl L-Carnitine in COVID-19 Patients With Mild-to-Moderate Disease Coronavirus disease 19 infection, Viral pneumonia acetyl L-Carnitine alone, standard of care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone Palermo Italy 2020-12-15 2021-07-31 20201109, NCT04623619 Phase Not Applicable Not yet recruiting 1 7 Months 100 Antonio Cascio, MD, PhD 2020-11-19
A clinical trial of SARS-CoV-2-RBD nanoparticle vaccine, University of Washington for the potential prevention of COVID-19 infection Coronavirus disease 19 infection SARS-CoV-2-RBD nanoparticle vaccine, University of Washington alone Washington University School of Medicine, US Phase Not Applicable Planned 0 2020-11-11
COMPVID STUDY: Randomized, controlled study of inflammation inhibition in the treatment of pneumonia by the SARS-Cov-2 virus Coronavirus disease 19 infection, Viral pneumonia nomacopan alone Complement C5 factor inhibitor, Leukotriene BLT receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hospital Eduardo de Menezes, Universidade Federal de Minas Gerais Brazil 2020-08-19 2021-01-31 35247020.9.0000.5124, 4.165.354, COMPVID STUDY, RBR-88bjcv, U111112603293 Phase 2 Clinical Recruiting 1 5 Months Glauciene Prado Alves Prado Alves, Mauro Martins Teixeira 2020-11-13
AEROBI - COVID: Effect of Moderate Physical Training on a bicycle associated with altitude simulation on the health status of people recovered from COVID-19 Coronavirus disease 19 infection hypoxia alone, normoxia alone, recovery alone, training alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Escola de Educação Física e Esporte de Ribeirão Preto, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, University of Sao Paulo Fundacao de Amparo a Pesquisa do Estado Sao Paulo Brazil 2020-09-11 2021-04-30 33783620.6.0000.5659, 33783620.6.3001.5403, AEROBI - COVID, RBR-5d7hkv, U1111-1260-7479 Phase Not Applicable Recruiting 1 7 Months 80 Atila Alexandre Trapé 2020-11-16
Hyperbaric Oxygen for COVID-19 Patients With Moderate to Severe Respiratory Distress Coronavirus disease 19 infection, Respiratory distress syndrome Standard of Care alone, hyperbaric oxygen alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) NYU Langone Health US 2020-11-16 2021-12-15 20-00897, NCT04619719 Phase 2 Clinical Not yet recruiting 2 13 Months 600 David Lee, MD, Sandra Wainwright, MD, Scott Gorenstein, MD 2020-11-12
CortiCORONA: Biomarkers for Dexamethasone Response in Sars-Cov-2/COVID-19 Pneumonia Coronavirus disease 19 infection, Viral pneumonia dexamethasone alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital, Montpellier France 2020-11-18 2021-09-18 2020-A0206-33, CortiCORONA, NCT04619693, PHRCI-20-013, RECHMPL20_0292 Phase Not Applicable Recruiting 2 10 Months 100 Alain Makinson, MD, Boris Jung, MD, PhD, Bourdin Arnaud, MD, PhD, Camille Roubille, MD, Clement Boissin, MD, Clément Boissin, MD, Clément Le Bihan, MD, David Morquin, MD, Edouard Tuaillon, MD, PhD, Jacques Reynes, MD, PhD, Jean-Pierre Mallet, MD, Jérémy Charriot, MD, Kada Klouche, MD, PhD, Khuder Alagha, MD, Nathalie Pansu, MD, Pierre Fesler, MD, Sébastien Bommart, MD, PhD, Vincent Le Moing, MD 2020-11-26
COVISTRESSNutr: Influence of the COVID-19 Pandemic on Stress and Eating Habits Acute stress disorder, Coronavirus disease 19 infection Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Clermont-Ferrand France 2020-04-01 2025-12-31 2020 COVISTRESS NUTRITION, COVISTRESSNutr, NCT04621084 Phase Not Applicable Recruiting 1 69 Months 1000 Frederic DUTHEIL, Lise Laclautre, lise laclautre 2020-11-16
Hydroxychloroquine, Azithromycin and Zinc for the Treatment of COVID-19 in the Outpatient Setting Coronavirus disease 19 infection Variable regimens including azithromycin , hydroxychloroquine , zinc sulfate Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) St. Francis Hospital, New York US 2020-11-30 2021-05-31 20-19, NCT04621461 Phase 4 Clinical Not yet recruiting 1 6 Months 750 Avni Thakore, MD, Elizabeth Haag, RN, Elizabeth S Haag, RN 2020-11-11
Effect of a Cloth Mask Physical Exercise session on Cardiovascular health, Feeling and Exercise Effort, Oxygen Quantity and Jumping Performance: Recommendation for Physical Mask Exercise during and after the COVID-19 global outbreak Cardiovascular disease, Coronavirus disease 19 infection cloth mask alone, exercise alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Universidade Federal do Rio Grande do Norte Brazil 2020-11-02 RBR-9b6kvp, U1111-1259-3641 Phase Not Applicable Not yet recruiting 1 30 Phelipe Wilde de Alcântara Varela 2020-11-11
Effectiveness of a mouthwash and toothpaste containing PHTALOX in controlling symptoms of COVID-19 and flu Coronavirus disease 19 infection, Influenza virus infection Kit for oral care alone, PHTALOX alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto Federal do Paraná - IFPR Brazil 2020-11-01 35530020.1.0000.8156, 4.355.065, RBR-8x8g36, U1111-1260-4839 Phase 3 Clinical Not yet recruiting 1 500 Marcelo Lupion Poleti 2020-11-12
COnV-ert: Plasma for Early Treatment in Non-hospitalized Mild or Moderate COVID-19 Patients Coronavirus disease 19 infection, Lower respiratory tract infection methylene blue treated convalescent anti-SARS-CoV-2 plasma alone, standard medical treatment alone Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Fundacio Lluita Contra La Sida Banc De Sang I Teixits, Germans Trias i Pujol Hospital, Grifols Biologicals Inc, irsiCaixa Foundation Spain 2020-10-30 2021-10-31 CONV-ERT, COnV-ert, NCT04621123 Phase 2 Clinical Recruiting 1 12 Months 474 ORIOL Mitjà Villar, MD,PhD, ORIOL Mitjà Villar, MD,Phd, Oriol Mitjà Villar, PhD, MD 2020-11-13
MOMA: Measurement of the effect of mouthwash against COVID-19 Coronavirus disease 19 infection Dentyl mouthwash alone, Ultradex alone, povidone-iodine alone Cardiff University Venture Life Ltd UK 2020-05-20 2020-12-27 IRAS 285247, ISRCTN25647404, MOMA Phase 2 Clinical Recruiting 3 7 Months 104 Prof Thomas 2020-11-17
Innovation of Audio-Visual Triage System in Combating the Spread of COVID-19 Infection and Its Efficacy: A Novel Strategy Anxiety disorder, Coronavirus disease 19 infection audio-visual triage system alone Healthy volunteers accepted, Young Adults (18-44 yrs) University of Lahore, Main Campus Pakistan 2020-03-21 2020-04-28 IRBEC/BIH/013-2020, NCT04621214 Phase Not Applicable Completed 1 1 Month 60 Dr Muhammad Mansoor Hafeez 2020-11-13
PROVID-19: Efficacy of Probiotics in Reducing Duration and Symptoms of COVID-19 Coronavirus disease 19 infection probiotic intake alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre hospitalier universitaire de Sherbrooke Lallemand Health Solutions Canada 2020-11-16 2021-03-31 2021-3700, NCT04621071, PROVID-19 Phase Not Applicable Not yet recruiting 1 4 Months 84 Audrey Hamel-Thibault, MSc, Blanche Senicourt, PhD, Jean-Charles Pasquier, Dr, Jean-Charles Pasquier, MD, PhD 2020-11-27
Investigating effect of Spirulina dietary supplementation on COVID-19 disease outcomes in patients admitted to Intensive Care Units Coronavirus disease 19 infection routine medication alone, spirulina supplement alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Islamic Azad University Iran 2020-11-21 IR.IAU.PS.REC.1399.063, IRCT20200720048139N1 Phase 2 Clinical Recruiting 1 138 Farshad Hashemian, Mahdi Shadnoush, Monireh Hatami 2020-11-23
ENDCOV-I: The Study Will Evaluate the Use of Nintedanib in Slowing Lung Fibrosis in Patients With Pulmonary Infiltrates Related to COVID-19 Coronavirus disease 19 infection, Interstitial lung disease, Pulmonary fibrosis nintedanib alone CSF-1 antagonist, FGF receptor antagonist, FGF1 receptor antagonist, FGF2 receptor antagonist, FGF3 receptor antagonist, Flt3 tyrosine kinase inhibitor, Lck tyrosine kinase inhibitor, Lyn tyrosine kinase inhibitor, PDGF receptor alpha antagonist, PDGF receptor antagonist, PDGF receptor beta antagonist, Src tyrosine kinase inhibitor, VEGF receptor antagonist, VEGF-1 receptor antagonist, VEGF-2 receptor antagonist, VEGF-3 receptor antagonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mount Sinai Medical Center Boehringer Ingelheim International GmbH US 2020-11-30 2021-07-31 ENDCOV-I, GCO 20-2147, NCT04619680 Phase 4 Clinical Recruiting 2 8 Months 120 Aditi Mathur, MD, Alona Lansky, Jigna Zatakia, Maria Padilla, MD 2020-11-25
Seroprevalence of COVID-19 antibodies Coronavirus disease 19 infection Adolescents (13-17 yrs), Young Adults (18-44 yrs) Kalinga Institute of Medical Sciences India 2020-11-15 CTRI/2020/11/028967 Phase Not Applicable Not yet recruiting 6 100 Ramnath Misra 2020-11-11
A study to observe the trend of SARS-CoV-2, Dengue and Chikungunya infection transmission in the general population Chikungunya virus infection, Coronavirus disease 19 infection, Dengue virus infection Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Biotechnology Industry Research Assistance Council India 2020-11-18 CTRI/2020/11/028968 Phase Not Applicable Not yet recruiting 1 5000 DrYuvarajJayaraman 2020-11-12
Effect of Group Otago Exercise Program on Cognitive Frailty in the Nursing Home: a Randomized Controlled Trial Cognitive disorder, Coronavirus disease 19 infection Otago exercise alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) The Second XiangYa Hospital of Central South University, Xiangya School of Medicine of Central South University Health and Family Planning Commission of Hunan Province China 2020-06-01 2020-10-13 ChiCTR2000039592 Phase 0 Clinical Completed 1 4 Months 62 Chen Xi 2020-11-12
Effect Of COVID-19 on breast cancer treatment and its outcome Breast tumor, Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tata Memorial Hospital India 2020-11-16 CTRI/2020/11/028969 Phase Not Applicable Not yet recruiting 2 900 Dr Jince Mary Mathew, Dr Rajiv Sarin 2020-11-11
A clinical trial to assess JNJ-78436735 in youths aged 12 to 18 for COVID-19 Coronavirus disease 19 infection JNJ-78436735 alone Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Johnson & Johnson Phase Not Applicable Planned 0 2020-11-11
Intubation with VieScope versus Videolaryngoskopy in complete personal protecion gear in asimulated COVID-19-Patient - A randomized, controlled trial Coronavirus disease 19 infection Glidescope alone, VieScope alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Cologne Germany 2020-11-15 20-1465, DRKS00023406 Phase Not Applicable Not yet recruiting 1 35 Hannes Ecker 2020-11-12
COVID-19 Stress, Depression, and Anxiety Among Health Care Workers in Selangor Hospitals Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection, Depression Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) HOSPITAL TENGKU AMPUAN RAHIMAH KLANG Malaysia 2020-11-09 2022-12-31 56884, NMRR-20-2388-56884 Phase Not Applicable Not yet recruiting 1 25 Months Dr Natasha Subhas 2020-11-15
Evaluation of the combined effect of Hesperidin,Artemisinin- Artemisia annua, Noscapine, N-acetylcysteine, Resveratrol supplements and high dose of vitamin C on treatment, clinical symptoms of non-hospitalization and hospitalization patients with symptomatic COVID-19 Coronavirus disease 19 infection Variable regimens including Artemisia annua - Artemisinin, Longlifenutri , N-acetyl cysteine, Osvah , hesperidin, Swanson , noscapine, Faran Shimi , resveratrol, A Squard , vitamin C, Daroupakhsh Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kerman University of Medical Sciences Iran 2020-10-07 IR.SIRUMS.REC.1399.033, IRCT20181030041504N1 Phase 3 Clinical No longer recruiting 1 100 Dr. Masoomeh Mohamadpour, Dr.Ali,Amjadi, دکتر علی امجدی 2020-11-13
The Prevalence of Malnutrition among Adult Patients with the Coronavirus Disease 2019 (COVID 19) in a Tertiary Government Hospital Coronavirus disease 19 infection, Malnutrition Philippine General Hospital Philippines 2020-07-14 2020-09-15 PHRR201109-003131 Phase Not Applicable Completed 1 2 Months Blessie Marie B. Perez, Harold Henrison Chiu, MD, Lia Aileen M. Palileo-Villanueva, MD, Ramon B. Larrazabal Jr. 2020-11-13
Knowledge and attitudes of healthcare personnel towards COVID-19 disease and infection control strategies in a tertiary-level government hospital and COVID-19 referral center in the Philippines Coronavirus disease 19 infection Healthy volunteers accepted Philippine General Hospital Philippines 2020-06-01 2020-12-01 PHRR201109-003132 PHRR201109-003132 Phase Not Applicable Recruiting 1 6 Months Janine G. Mendoza, Maria Sonia Salamat, MD, Nigel Cortez Santos 2020-11-11
Determination the therapeutic effect of Ivermectin and Sovodak on patients infected with COVID-19 Coronavirus disease 19 infection standard regimen therapy alone, Sovodak plus ivermectin Chloride channel modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Akam Tejarat Fartak Farasoo Iran 2020-10-16 IR.QUMS.REC.1399.228, IRCT20200408046987N2 Phase 2/Phase 3 Clinical Recruiting 1 150 Dr. Aliakbar Karami, Dr Elham Zsabganeh, Morteza Shakhs Niaee, Nematollah Gheibi 2020-11-12
Effect of Dexamethasone on treatment of COVID-19 Coronavirus disease 19 infection dexamethasone alone, standard treatment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tehran University of Medical Sciences Iran 2020-09-11 IR.TUMS.MEDICINE.REC.1399.432, IRCT20201015049030N1 Phase 2 Clinical Recruiting 4 200 Ali Asadolahi Amin, Mahdi Mahmoudi, Maryam Akhtari, Mohamadreza Salehi, Mohammad Ali Sahraian, Mojtaba Hedayat Yaghoobi, Saeed Reza Jamali Moghadm 2020-11-11
Effect of recombinant erythropoietin in COVID-19 patients Coronavirus disease 19 infection, Viral pneumonia recombinant erythropoietin (r-EPO) alone, standard care alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) All India Institute of Medical Sciences India 2020-11-06 CTRI/2020/11/028959 Phase 2 Clinical Not yet recruiting 1 40 Ashutosh kumar singh, Prof Anjan Trikha 2020-11-11
Psychological burden in COVID-19 Anxiety disorder, Coronavirus disease 19 infection, Depression, Somatization disorder Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) All India Institute of Medical Sciences India 2020-11-10 CTRI/2020/11/028954 Phase Not Applicable Not yet recruiting 1 100 Bichitra Nanda Patra 2020-11-10
FUSIC: Ultrasonography in COVID-19 patients with a focus on possible clinical diagnosis and management decisions Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Pushpagiri Institute of Medical Sciences & Research Centre India 2020-11-19 CTRI/2020/11/028938, FUSIC Phase Not Applicable Not yet recruiting 1 44 Manju Mathew 2020-11-10
Outpatient Treatment With CoVid-19 With Prexablu Coronavirus disease 19 infection NocUlite alone, low level light therapy alone, methylene blue (Prexablu) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Instituto De Seguridad Y Servicios Sociales De Los Trabajadores Del Estado Mexico 2020-10-12 2020-12-30 064.I.2020, NCT04619290 Phase 1 Clinical Recruiting 1 2 Months 46 M. Eunice Rodríguez Arellano, Martha E. Rodríguez Arellano, MD, Paula Costa Urrutia, PhD, Robin Messier 2020-11-13
RE-CoV-ERY: Post-intensive Care Follow-up of Patients Hospitalized for an Acute Respiratory Distress Syndrome Caused by COVID-19 Coronavirus disease 19 infection, Post traumatic stress disorder, Respiratory distress syndrome Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Hospitalier Universitaire de Toulouse France 2020-07-27 2022-07-31 NCT04619368, RC31/20/0219, RE-CoV-ERY Phase Not Applicable Recruiting 1 24 Months 100 Fanny BOUNES, Fanny BOUNES, PH 2020-11-11
A trial to evaluate an at-home rapid antigen test for COVID-19 Coronavirus disease 19 infection at-home rapid antigen test alone Gauss Surgical Phase Not Applicable Status not specified 0 159 2020-11-10
Physical Activity a Vital Sign? 40 Steps to Safety Test for Patients With COVID-19 Coronavirus disease 19 infection 40-steps test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Betsi Cadwaladr University Health Board Oxford Brookes University UK 2020-11-03 2021-11-03 283998, NCT04618835 Phase Not Applicable Recruiting 1 12 Months 1000 Christian Subbe, Christian Subbe, DM, Dr Christian P Subbe, Laura Langshaw 2020-11-12
COVISTRESSWork: Influence of the COVId-19 Pandemic on Stress of Occupational Health Workers Acute stress disorder, Coronavirus disease 19 infection Healthy volunteers accepted, Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University Hospital Clermont-Ferrand France 2020-06-01 2025-12-21 2020 COVISTRESS WORK, COVISTRESSWork, NCT04619576 Phase Not Applicable Recruiting 1 66 Months 1000 Frederic DUTHEIL, Lise Laclautre, lise laclautre 2020-11-11
Safety and Immunogenicity of COVI-VAC, a Live Attenuated Vaccine Against COVID-19 Coronavirus disease 19 infection COVI-VAC alone Healthy volunteers accepted, Young Adults (18-44 yrs) Codagenix Inc UK 2020-12-31 2022-05-31 CDX-COV-001, NCT04619628 Phase 1 Clinical Not yet recruiting 1 17 Months 48 Daryl Bendel, MD, Kingsley Eze, Sybil Tasker, MD, MPH 2020-11-17
Ultramicronized Palmitoylethanolamide (PEA) Treatment in Hospitalized Participants With COVID-19 Coronavirus disease 19 infection palmidrol + morphine (ultramicronized, severe chronic pain), FSD Pharma alone, standard of care alone Cannabinoid CB2 receptor modulator, Opioid receptor mu agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) FSD Pharma Inc 2020-11-15 2021-12-05 FSD201-03, NCT04619706 Phase 2a Clinical Not yet recruiting 0 12 Months 350 FSD BioSciences Head of Clinical Research 2020-11-10
Surfactant Protein D Levels in Covid-19 Infection: Case-Control Study Coronavirus disease 19 infection, Viral pneumonia Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Kafkas University Turkey 2020-10-13 2020-11-02 CLINICAL-1, NCT04618861 Phase Not Applicable Completed 1 127 Ramazan Sbirli 2020-11-11
A Single-Dose Study to Determine the Safety and Tolerability of Intranasal REVTx-99 in Healthy Adult Volunteers Coronavirus disease 19 infection REVTx-99 alone TLR-4 agonist Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Linear Clinical Research Limited, Statistical Revelations Australia 2020-11-12 2020-12-24 2020-08-796, ACTRN12620001104943, ANZCTR380621, RVL-NHV01 Phase 1 Clinical Recruiting 1 1 Month 32 Carol Odle, George Tidmarsh, Jasmine Williams 2020-11-24
ASK: Improving access to kidney transplantation Coronavirus disease 19 infection, Kidney transplantation Clinician letter alone, Home-based patient and family education and engagement alone, Remote virtual ‘visit’/link alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Bristol, Wellcome Trust Wellcome Trust UK 2018-01-01 2023-02-01 , SPONSOR'S NUMBER 2020-4883, WT 214554/Z/18/Z, ASK, IRAS 287507, ISRCTN10989132 Phase Not Applicable Not yet recruiting 3 61 Months 60 Dr Bailey 2020-11-19
COKITS: Screening for COVID-19 in Teachers, Childcare Educators, Pupils and Preschoolers Coronavirus disease 19 infection Anti-SARS-CoV-2 antibody testing alone, SARS-CoV-2 PCR test alone Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University Medicine Greifswald Government of Mecklenburg-Western Pomerania, Landesamt für Gesundheit und Soziales M-V Germany 2020-11-04 2021-03-31 BB 179/20, COKITS, NCT04619407 Phase Not Applicable Recruiting 1 4 Months 300 Karsten Becker, Prof. Dr., Lena Ulm, Dr., Nils-Olaf Hübner, Prof. Dr. 2020-11-11
A phase II clinical trial of 7HP-349 in combination with COVID-19 vaccine for the treatment of patients with COVID-19 infection Coronavirus disease 19 infection 7HP-349 plus COVID-19 vaccine CD11a agonist, CD49d agonist, ICAM-1 stimulator, Integrin agonist, Vascular cell adhesion protein 1 agonist 7 Hills Pharma Llc Phase 2 Clinical Planned 0 2020-11-25
A Comparison of Fiberoptic Endotracheal Intubation Between the Intubating Laryngeal Tube Suction and the LMA Protector Coronavirus disease 19 infection, Respiratory disease LMA Protector alone, disposable intubating laryngeal tube suction device alone, endotracheal tube (VBM Medizintechnik GmbH) alone, fiberscope (Karl Storz) alone, Variable regimens including fentanyl , nitrous oxide , oxygen , propofol, AstraZeneca/Fresenius , rocuronium bromide , sevoflurane Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) B'nai Zion Medical Center Israel 2020-11-01 2020-12-30 NCT04618926, PROTECTOR Phase Not Applicable Not yet recruiting 1 1 Month 80 LUIS.GAITINI, Luis Gaitini, M.D., Mostafa Somri, M.D. 2020-11-13
Effect of COVID-19 Pandemic on Vaccination Compliance Coronavirus disease 19 infection Infants (6-23 months), Preschool Children (2-5 yrs) Assiut University Egypt 2021-04-01 2022-05-01 EFFECT OF COVID ON VACCINATION, NCT04618796 Phase Not Applicable Not yet recruiting 1 13 Months 100 Gehad Gamal Ahmed, Gehad Gamal, resident doctor, Ismail lotfy, associated professor, Mohamed Hamdy, professor 2020-11-10
A Phase II Clinical Trial of Influenza virus Vector COVID-19 Vaccine for intranasal Spray (DelNS1-2019-nCoV-RBD-OPT1) Coronavirus disease 19 infection, Viral pneumonia COVID-19 XWG-03 alone COVID19 Spike glycoprotein modulator Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Beijing Wantai Biological Pharmacy Enterprise Co Ltd, Jiangsu Province Centers for Disease Control and Prevention China 2020-11-17 2021-12-17 ChiCTR2000039715 Phase 2 Clinical Not yet recruiting 1 13 Months 720 Fengcai Zhu, Xiangzhong Ye 2020-11-17
The impact of COVID-19 on selective orthopedic surgery in Shanghai Sixth People's Hospital Coronavirus disease 19 infection selective orthopedic surgery alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Shanghai Sixth People’s Hospital China 2020-11-08 2020-12-08 ChiCTR2000039711 Phase Not Applicable Recruiting 1 1 Month 2000 Cunyi Fan, Tengfei Lou 2020-11-11
ProMusik: Prospective, cohort study on the incidence of SARS-CoV-2-infections (COVID-19) in professional orchestra musicians and choir singers Coronavirus disease 19 infection, Influenza virus infection, Upper respiratory tract infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Charite Universitaetsmedizin Berlin Germany 2020-10-02 DRKS00023385, EA1/237/20, ProMusik Phase Not Applicable Recruiting 10 2500 Anne Berghöfer 2020-11-11
Evaluation of the effectiveness of TAC cocktail in critically ill patients with COVID-19-induced pneumonia Coronavirus disease 19 infection, Viral pneumonia Variable regimens including ascorbic acid (Darou Pakhsh Co) , methylprednisolone (Pfizer) , thiamine (Darou Pakhsh Co) Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Tehran University of Medical Sciences Iran 2020-04-04 IR.TUMS.VCR.REC.1399.070, IRCT20200415047080N2 Phase 2/Phase 3 Clinical No longer recruiting 1 30 Mohammad ali Sahraian, Rasol Aliannejad, Rasoul Aliannejad 2020-11-10
COVID-19 With Convalescent Plasma Coronavirus disease 19 infection convalescent plasma therapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Southeast University China 2020-01-01 2020-11-01 COVID-19 CONVALESCENT PLASMA, NCT04616976 Phase Not Applicable Completed 1 10 Months 78 Chun Pan 2020-11-10
A clinical trial of NanoAgCide hand sanitizer on Coronavirus patients Coronavirus disease 19 infection colloidal silver (NanoAgCide) alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) WeInnovate Biosolutions Pvt Ltd India 2020-10-31 CTRI/2020/10/028688 Phase 2 Clinical Recruiting 1 20 Dr Ramshyam C Agarwal, Prasad Bhagat, Subham Dutta 2020-11-10
SAFE KiDS Studie: Rapidly applicable surveillance process for COVID-19 in day care centers with dual swabs Coronavirus disease 19 infection RT-PCR alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Johann Wolfgang Goethe-Universitat Frankfurt am Main Hessian Ministry for Social Affairs and Integration, Roche Holding AG Germany 2020-06-18 2020-09-10 20-724, DRKS00023500, SAFE KiDS Studie Phase Not Applicable Completed 1 2 Months 1250 Sandra Ciesek 2020-11-11
Effect of dexamethasone or ibuprofen-acetaminophen combination for pain management in symptomatic apical periodontitis during COVID-19 outbreak: a retrospective cohort study Coronavirus disease 19 infection, Pain dexamethasone alone, acetaminophen plus ibuprofen Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Istanbul Medeniyet University 2020-10-04 TCTR20201027002 Phase Not Applicable Not yet recruiting 0 50 Hakan Arslan 2020-11-10
SILVAR: Siltuximab in Viral ARds (SILVAR) Study Coronavirus disease 19 infection, Respiratory distress syndrome siltuximab alone, standard-of-care alone Heat shock protein inhibitor, IL-6 receptor antagonist Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) EUSA Pharma Syneos Health Inc US 2020-11-02 2022-06-30 EUSA SYL 0004, NCT04616586, SILVAR Phase 3 Clinical Not yet recruiting 1 19 Months 555 Melahat Samali, Nancy E Zeleniak, Tina Karunaratne, Zainab Shahid, MD, Ph.D, Zainab Shahid, MD, PhD 2020-11-11
Study of the Commercial Scale SARS-CoV-2 Vaccine Against the Pilot Scale Among Adults, and Bridging Study of the Immunogenicity in Elderly Against That in Adults Coronavirus disease 19 infection CoronaVac alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Sinovac Research & Development Co Ltd China 2020-10-31 2021-05-31 NCT04617483, PRO-NCOV-3001 Phase 3 Clinical Recruiting 1 7 Months 1040 Hengkui Zhi, Master, Hongxing Pan, Master 2020-11-09
KOVID: Impact of the COVID-19 Epidemic on the Hospital Journey of Patients With Cancer of the Digestive System Anal tumor, Biliary cancer, Colon tumor, Coronavirus disease 19 infection, Esophagus tumor, Gallbladder tumor, Gastrointestinal tumor, Liver tumor, Pancreas tumor, Rectal tumor, Small intestine cancer, Stomach tumor Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Groupe Hospitalier Paris Saint-Joseph France 2020-12-01 2021-12-31 KOVID, KOVID, NCT04616950 Phase Not Applicable Not yet recruiting 1 13 Months 800 Anne BURONFOSSE, MD, Helene BEAUSSIER, PharmD, pHD 2020-11-11
A Clinical Study of Online Active Play Program With Adolescents Anxiety disorder, Coronavirus disease 19 infection, Depression Revival Active Program alone Children (6-12 yrs), Adolescents (13-17 yrs) Revival Active Aarogyam UK UK 2020-03-30 2020-07-28 NCT04618341, RAP/003 Phase Not Applicable Completed 1 3 Months 32 Nagamani Krishnamurthy, Rakesh Patel, Tejal Patel 2020-11-17
Home-based Exercise in COVID-19 Survivors Coronavirus disease 19 infection telemonitored home-based exercise training program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) University of Sao Paulo Brazil 2020-09-26 2021-12-21 4.342.082, NCT04615052 Phase Not Applicable Recruiting 1 14 Months 60 Bruno Gualano, Bruno Gualano, PhD, Bruno Gualano, Phd 2020-11-09
Effect of Solution-Focused Support Program on Anxiety Levels of Parents During the COVID-19 Pandemic Anxiety disorder, Coronavirus disease 19 infection Solution-Focused Support Program alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Adiyaman University Research Hospital Turkey 2020-07-01 2020-12-30 2020/751, NCT04609722 Phase Not Applicable Recruiting 1 5 Months 60 Ceyda Başoğul, Ceyda Başoğul, PhD, Emriye Hilal Yayan, Mürşide .zengin, Mürşide Zengin 2020-11-09
Heart Up!: Reducing Hopelessness Through Improved Physical Activity in Adults With Heart Disease: With COVID-19 Considerations Coronavirus disease 19 infection, Ischemic heart disease, Myocardial infarction, Unstable angina Motivational social support from nurse alone, Motivational social support from nurse with additional support from significant other alone, mHealth intervention alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Illinois National Institute of Nursing Research US 2019-08-01 2023-05-31 2018-1485, 3R01NR017649-04S1, Heart Up!, NCT03907891, R01NR017649 Phase Not Applicable Recruiting 1 46 Months 225 Denise K Busman, MSN, Stacie Vanoosterhout, MS, Susan L Dunn, PhD 2020-11-11
Online MBI for Families Affected by PPDA Anxiety disorder, Coronavirus disease 19 infection, Depression mindfulness-based cognitive therapy alone, mindfulness-based stress reduction program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Children's & Women's Health Centre of British Columbia (C&W) Canada 2020-10-20 2022-08-31 H20-01884, NCT04617132 Phase Not Applicable No longer recruiting 1 22 Months 40 Katarina Tabi, S. Evelyn Stewart 2020-11-10
Nasal Photodisinfection COVID Proof of Concept Study Coronavirus disease 19 infection Steriwave nasal decolonization system (Ondine Biomedical, BC) alone, methylene blue alone, red-light exposure based photodisinfection alone Sunnybrook Health Sciences Centre Canada 2020-07-10 2021-05-31 NCT04615936, NasalPDF001 Phase 2 Clinical Recruiting 1 10 Months 100 Cari Whyne, PhD, Jeremie Larouche, MD, MSc, Ravi Tuazon, BSc 2020-11-09
Effect of Respiratory Versus Aerobic Training on Respiratory and Immunity Efficiency in Recovered COVID-19 Patients Coronavirus disease 19 infection diaphragmatic breathing training alone, endurance training alone, incentive spirometer alone, intermittent exercise alone, medical drug treatment alone, segmental breathing training alone, treadmill walking alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Cairo University Egypt 2020-07-02 2021-01-20 MAHA2020, NCT04613050 Phase Not Applicable Recruiting 1 6 Months 80 Heba Ahmed Ali Abdeen, Maii Fekry Foad, MD 2020-11-10
Management of appendicitis during the covid-19 pandemic (observational) Appendicitis, Coronavirus disease 19 infection Hyperspace Epic 2014 Version IU1, Epic Systems Corporation alone, Laparoscopic appendicectomy alone, Open appendicectomy alone Healthy volunteers accepted, Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Cambridge University Hospitals NHS Foundation Trust Addenbrookes NHS Trust, Nuffield Health Bournemouth, University of Rochester Medical Center UK 2019-11-01 2020-10-06 NCT04615728, PRN8996 Phase Not Applicable Completed 1 11 Months 207 Mr Ramez Antakia, Mr 2020-11-10
Prevalence of Thrombosis in COVID-Patients Coronavirus disease 19 infection, Thrombosis Duplex ultrasound alone, blood test alone, cognitive test alone, smelling test alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Klinikum Augsburg Germany 2020-11-04 2021-06-30 COVID THROMBOSE, NCT04615026 Phase Not Applicable Recruiting 1 7 Months 400 Alexander Hyhlik-Duerr, MD, Yvonne Gosslau, MD 2020-11-09
SUMMIT: Scaling Up Maternal Mental Health Care by Increasing Access to Treatment Anxiety disorder, Coronavirus disease 19 infection, Depression TelePsychiatry Program alone, manualized behavioral activation treatment alone Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Mount Sinai Hospital Harvard Medical School, NorthShore University HealthSystem (NorthShore), Patient Centered Outcome Research Institute, St Michaels Hospital, Sunnybrook Health Sciences Centre, University of Colorado, Boulder, University of North Carolina, Women's College Hospital US, Canada 2020-01-06 2025-12-30 NCT04153864, PCS-2018C1-10621, SUMMIT Phase Not Applicable Recruiting 5 71 Months 1368 Anastasia Harris, Cindy-Lee Dennis, Daisy R Singla, PhD, Holly Krohn, Maria Michalowska, Richard K Silver, MD, Samantha Meltzer-Brody, MD, MPH, Simone Vigod 2020-11-09
An observational, retrospective, single-center study to determine the efficacy and safety of tocilizumab in patients with severe COVID-19 infection Coronavirus disease 19 infection tocilizumab alone Albert Einstein Healthcare Network Phase Not Applicable Status not specified 0 66 2020-11-06
ENSEMBLE 2: A Study of Ad26.COV2-S for the Prevention of SARS-CoV-2-mediated COVID-19 in Adults Coronavirus disease 19 infection JNJ-78436735 alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Janssen Vaccines & Prevention BV Janssen Pharmaceuticals Inc, National Institute for Health Research (NIHR) France, Belgium, Colombia, Philippines, US, Spain, Germany, South Africa, UK 2020-11-15 2023-05-11 2020-003643-29, CPMS 46804, CR108916, ENSEMBLE 2, IRAS 288552, ISRCTN14722499, NCT04614948, VAC31518COV3009 Phase 3 Clinical Recruiting 110 29 Months 30000 Janssen Vaccines & Prevention B.V. Clinical Trial, Mr Malcolm Macartney, Ms Shola Ayeni, Study Contact 2020-11-26
FX-COVID: FX-06 to Rescue Acute Respiratory Distress Syndrome During Covid-19 Pneumonia Coronavirus disease 19 infection, Respiratory distress syndrome, Viral pneumonia FX-06 alone Cadherin-5 modulator, Factor Ia modulator Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Assistance Publique Hopitaux de Paris France 2020-11-30 2021-07-31 2020-002056-20, APHP200495, FX-COVID, NCT04618042 Phase 2 Clinical Recruiting 1 8 Months 50 BRECHOT Nicolas, MD, David HAJAGE, MD, Nicolas BRECHOT, MD 2020-11-25
An observational study to evaluate the correlation between complement activation and disease severity in patients hospitalized with COVID-19 Coronavirus disease 19 infection Apellis Pharmaceuticals Inc Phase Not Applicable Status not specified 0 41 2020-11-19
Analysis of the immunological response to coronavirus infection Coronavirus disease 19 infection Healthy volunteers accepted The University of Birmingham Department of Health and Social Care, Medical Research Council UK 2020-04-01 2025-06-05 CPMS 46588, IRAS 282164, RG_20-038 COVID-19, ISRCTN63911163 Phase Not Applicable Recruiting 4 62 Months 600 Dr Rachel Bruton, Prof Paul Moss 2020-11-09
SEMPATICO: Semaglutide to Reduce Myocardial Injury in Patients With COVID-19 Coronavirus disease 19 infection, Heart injury semaglutide (subcutaneous, diabetes/obesity/NASH), Novo Nordisk alone, standard of care alone Glucagon-like peptide 1 receptor agonist Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) The University Health Network Canadian Institutes of Health Research, St Michaels Hospital, University of Toronto Canada, UK, Brazil, Mexico 2020-11-30 2022-03-31 NCT04615871, SEMPATICO, UHNSEMPATICO1 Phase 2 Clinical Not yet recruiting 10 16 Months 400 Andrei C Sposito, MD, Anil Gupta, MD, Beatriz Villegas, DDS, Carlos Fernando, Cheryl Geen-Smith, Daniela M Rosiles, MD, Eduardo Mateos, MD, Emily McDonald, MD, Gina Dutton, Jorge Escobedo, MD, Juan A Santillan, MD, Julieta Valenzuela, MD, Kim Connelly, MD, Mansoor Husain, MD, Priscilla Griffo, Rodrigo B Esper, MD, Sarah Elsayed, Ticiane Bovi, Vinoda Sharma, MD, Vladimir Dzavik, MD, Vladimír Džavík, MD 2020-11-09
IMMUNO-COVID19: Hyperimmune Plasma for Patients With COVID-19 Coronavirus disease 19 infection, Respiratory distress syndrome hyperimmune plasma alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Ospedale Papa Giovanni XXIII Italy 2020-07-02 2022-07-02 IMMUNO-COVID19, IMMUNO-COVID19, NCT04614012 Phase Not Applicable Recruiting 1 24 Months 100 ANNA FALANGA, Anna Falanga 2020-11-09
Harnessing Network Science to Personalize Scalable Interventions for Adolescent Depression (TRACK to TREAT Phase II) Coronavirus disease 19 infection, Depression ecological sampling method app alone, psychoeducation alone, web-based behavioral activation single session intervention alone, web-based growth mindset single session intervention alone Children (6-12 yrs), Adolescents (13-17 yrs) State University of New York at Stony Brook US 2020-12-31 2024-08-31 IRB2019-00382, NCT04607902 Phase Not Applicable Not yet recruiting 1 44 Months 216 Jessica L Schleider, PhD 2020-11-09
PanDirect: Self-care Tools and Telephone Coaching for Depression and Anxiety During Pandemics Anxiety disorder, Coronavirus disease 19 infection, Depression lay telephone coaching alone, self-care tool alone Aged Adults (65-79 yrs), Elderly Adults (80 and over) St. Mary's Research Center Canada 2020-10-21 2021-05-01 NCT04609371, PanDirect, SMHC-20-10 Phase Not Applicable Recruiting 2 6 Months 176 Mark Yaffe, Mark Yaffe, Professor, 2020-11-20
NEOTHROCOVID: Thromboembolic Risk Screening in Patients With Cancer and COVID-19 Cancer, Coronavirus disease 19 infection, Thromboembolism computed tomography scan alone, electrocardiography alone, iodine alone, peripheral venous ultrasound alone, transthoracic ultrasound alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Centre Antoine Lacassagne (Nice) France, Monaco 2020-08-04 2021-09-15 2020/20, NCT04616846, NEOTHROCOVID Phase Not Applicable Recruiting 6 13 Months 120 Benjamin HOCH, MD-PHD, Christophe PERRIN, MD-PHD, Céline CELLIER-COËLLE, Denis DOYEN, MD-PHD, Jérome BARRIERE, MD-PHD, Jérôme DOYEN, MD-PHD, Ophélie CASSUTO, MD-PHD 2020-11-11
The Effects of Multi-modality Physiotherapy in Delaying or Preventing COVID-19 Patient From Admitting to ICU Coronavirus disease 19 infection, Viral pneumonia Threshold IMT device alone, conventional physical therapy alone, inspiratory muscle training alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Ministry of Health in Kuwait Kuwait 2020-11-01 2021-04-06 JALGHAITH, NCT04617119 Phase Not Applicable Not yet recruiting 1 5 Months 38 Abdulaziz Al-Husaini, MSc., DR. JASSIM ALGHAITH, Jassim M Alghaith, PhD. 2020-11-09
Food: A Three-Arm Study Examining Food Insecurity Interventions Breast tumor, Coronavirus disease 19 infection home grocery delivery alone, medically-tailored hospital-based food pantry access alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Memorial Sloan-Kettering Cancer Center Columbia University, Jacobi Medical Center, Lincoln Medical and Mental Health Center, Montefiore Health System, Queens Cancer Center of Queens Hospital, Roswell Park Comprehensive Cancer Center, St. Barnabas Medical Center, The Brooklyn Hospital Center US 2012-05-08 2022-05-31 12-099, Food, NCT01603316 Phase 2 Clinical Recruiting 7 120 Months 668 Caroline Hwang, MD, Francesca Gany, MD, MS, Francesca Gany, MD, PhD, Ilmana Fulger, MD, Jennifer Leng, MD, MPH, Tarek Elrafei, D.O. 2020-11-10
Compassionate Use of REGN-CoV2 for the Treatment of COVID-19 Coronavirus disease 19 infection REGN-CoV2 alone COVID19 Spike glycoprotein inhibitor Regeneron Pharmaceuticals Inc NCT04617535, R10933-10987-COV Phase Not Applicable Recruiting 0 2020-11-09
MIND-VR: Virtual Reality for COVID-19 Operators' Psychological Support Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection virtual reality-based protocol alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Fondazione IRCCS Istituto Neurologico Carlo Besta University of Milano-Bicocca Italy 2020-11-01 2021-11-01 MIND-VR, MIND-VR/BESTA, NCT04611399 Phase Not Applicable Not yet recruiting 1 12 Months 90 Eleonora F Orena, PhD, Federica Pallavicini, PhD 2020-11-10
Evaluation of antibody and cytokine detection in tears of COVID-19 patients Coronavirus disease 19 infection Healthy volunteers accepted, Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Postgraduate Institute of Medical Education and Research India 2020-11-10 CTRI/2020/11/028813 Phase Not Applicable Not yet recruiting 1 120 Reema Bansal 2020-11-10
AFFORD COVID: Asthma in Families Facing Out-of-pocket Requirements Due to COVID-19 Asthma, Coronavirus disease 19 infection AAFA's chat bot insurance navigation alone Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Harvard Pilgrim Health Care Asthma and Allergy Foundation of America, Harvard TH Chan School of Public Health, Patient Centered Outcome Research Institute, University of North Carolina US 2020-11-02 2023-01-31 AFFORD COVID, IHS-1602-34331, NCT04613739 Phase Not Applicable Not yet recruiting 1 26 Months 430 Alison Galbraith, MD, MPH, Lauren Cripps, MS 2020-11-10
Yoga program on COVID-19 patients Acute stress disorder, Coronavirus disease 19 infection integrated biofeedback based yoga program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Central Council for Research in Yoga and Naturopathy, Ministry of Ayush India 2020-11-04 CTRI/2020/11/028827 Phase Not Applicable Not yet recruiting 6 86 Dr Amit Agarwal, Dr Chhavi Gupta, Dr Deepak KK, Dr Minakshi Dhar, Dr Raghavendra Rao M, Dr Sudheer, Dr Sunitha Mondal 2020-11-09
CRI:SIS: COVID-19 Responsive Intervention: Systems Improvement Simulations (CRI:SIS) Acute stress disorder, Anxiety disorder, Coronavirus disease 19 infection Simulation intervention alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Yale University Agency for Healthcare Research and Quality US 2020-11-15 2022-11-15 1R01HS028340-01, 2000029372, CRI:SIS, NCT04614844 Phase Not Applicable Not yet recruiting 1 24 Months 84 Ambrose H Wong, MD, MSEd, Ambrose Wong, MD, MSEd, Leigh Evans, MD, Leigh V. Evans, MD 2020-11-10
Finding Wellness in the Pandemic Acute stress disorder, Alcoholism, Coronavirus disease 19 infection, Drug dependence trauma Informed Psychotherapy alone, trauma Informed Yoga alone Healthy volunteers accepted, Female, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) The University Of Lethbridge Canada 2020-11-01 2021-04-30 2020-096, NCT04615741 Phase Not Applicable Recruiting 1 6 Months 200 Cheryl Currie, Cheryl Currie, PhD 2020-11-11
SeroCovid < 19: A Prospective, COVID-19, Seroconversion Study in a Tertiary Pediatric Patient Cohort Coronavirus disease 19 infection SARS-CoV-2 serological assessment alone Newborn Infants (up to 5 months), Infants (6-23 months), Preschool Children (2-5 yrs), Children (6-12 yrs), Adolescents (13-17 yrs), Young Adults (18-44 yrs) Universitair Ziekenhuis Gent Universitaet Gent Belgium 2020-10-29 2021-11-01 BC-08104, NCT04615000, SeroCovid < 19 Phase Not Applicable Recruiting 1 12 Months 1000 Filomeen Haerynck, MD, PhD, Levi Hoste, MD 2020-11-10
Understanding Reactions to Emotional Material in the Media During COVID-19 Coronavirus disease 19 infection, Psychiatric disorder Tetris game alone Healthy volunteers accepted, Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) Uppsala University Sweden 2020-10-28 2021-01-15 2020-03991, NCT04608097 Phase Not Applicable Recruiting 1 2 Months 66 Emily Holmes, Prof, Laura Singh, PhD 2020-11-10
HLA-G-COVID: HLA-G Immuno-Inhibitor Checkpoint Study in Patients With COVID-19 Infection: Molecular and Cellular Assessment Coronavirus disease 19 infection cellular assessment alone, molecular assessment alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Hopital Foch France 2020-10-19 2021-10-31 2020_0082, HLA-G-COVID, NCT04613297 Phase Not Applicable Recruiting 1 12 Months 120 Elisabeth Hulier-Ammar, PhD, Olivier BRUGIERE, PhD 2020-11-09
PACBACK: Spinal Manipulation and Patient Self-Management for Preventing Acute to Chronic Back Pain Coronavirus disease 19 infection, Lower back pain Spinal manipulation therapy alone, Supported-self management program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) University of Minnesota Duke University, Oregon Health Sciences University, University of North Texas, University of Pittsburgh, University of Washington US 2018-10-25 COVID19_IMPACT, CSH-2018-26524, NCT03581123, PACBACK Phase 3 Clinical Suspended 3 1180 Gert Bronfort, PhD, DC 2020-11-09
Role of Physiotherapist in enhancing functional aerobic capacity in pulmonary rehabilitation in Covid-19 Patients Coronavirus disease 19 infection, Viral pneumonia pulmonary rehabilitation program alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs) Apollo Hospitals Educational Research Foundation Indraprastha Apollo Hospital India 2020-11-07 CTRI/2020/11/028811 Phase Not Applicable Not yet recruiting 1 50 Seema Grover 2020-11-09
Side effects of drugs used in ICU Coronavirus disease 19 infection Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs), Elderly Adults (80 and over) Government Institute of Medical Sciences, Greater Noida India 2020-11-13 CTRI/2020/11/028800 Phase Not Applicable Not yet recruiting 1 100 Dr Nazia Nazir 2020-11-10
The study of psychological interventions either individually or in groups and comparing its effect in reduction of psychological distress in covid-19 positive patients Acute stress disorder, Coronavirus disease 19 infection individual psychotherapy alone Young Adults (18-44 yrs), Middle-aged Adults (45-64 yrs), Aged Adults (65-79 yrs) HBTMC and Dr RN Cooper Municipal General Hospital India 2020-11-02 CTRI/2020/11/028799 Phase Not Applicable Not yet recruiting 1 55 Dr Deoraj sinha, Dr Tejaswini Miskin 2020-11-09